TAR DNA-binding protein 43

Overview


Name	TAR DNA-binding protein 43
Smed ID	SMED30015674
Length (bp)	4210

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of TAR DNA-binding protein 43 (SMED30015674) t-SNE clustered cells

Violin plots show distribution of expression levels for TAR DNA-binding protein 43 (SMED30015674) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TAR DNA-binding protein 43 (SMED30015674) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TAR DNA-binding protein 43 (SMED30015674) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30015674

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X2 cell	SMED30015674	SMESG000032661.1	SmedASXL_013532	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30015674	SMESG000032660.1	SmedASXL_014553	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30015674	SMESG000032661.1 SMESG000006486.1	dd_Smed_v4_1408_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30015674	SMESG000032661.1 SMESG000006486.1	dd_Smed_v4_1408_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30015674	SMESG000032661.1 SMESG000006486.1	dd_Smed_v4_1408_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015674	SMESG000032661.1	Contig22709	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015674	SMESG000032661.1	Contig22709	newmark_ests	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30015674	SMESG000045974.1	Contig4859	GPL15192	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30015674	SMESG000032661.1	Contig4859	GPL15192	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Match: TARDBP (TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571])

HSP 1 Score: 251.521 bits (641), Expect = 6.278e-73
Identity = 121/249 (48.59%), Postives = 167/249 (67.07%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L++YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 80.1073 bits (196), Expect = 7.960e-15
Identity = 35/81 (43.21%), Postives = 55/81 (67.90%), Query Frame = -2

Query: 3904 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4146
            ++K+ V    E++  ++LR+ F +YG V+D+FIPKPFR FAFVTF   ++AQ L G  + +KG ++ I +A PK   N++L
Sbjct:  190 SRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQL 270

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Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L++YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 80.1073 bits (196), Expect = 7.960e-15
Identity = 35/81 (43.21%), Postives = 55/81 (67.90%), Query Frame = -2

Query: 3904 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4146
            ++K+ V    E++  ++LR+ F +YG V+D+FIPKPFR FAFVTF   ++AQ L G  + +KG ++ I +A PK   N++L
Sbjct:  190 SRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQL 270

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Match: TARDBP (TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571])

HSP 1 Score: 246.899 bits (629), Expect = 7.571e-73
Identity = 121/249 (48.59%), Postives = 167/249 (67.07%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L++YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 78.9518 bits (193), Expect = 4.894e-15
Identity = 36/87 (41.38%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  ++LR+ F +YG V+D+FIPKPFR FAFVTF   ++AQ L G  + +KG ++ I +A PK   N++L    +F
Sbjct:  190 SRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF 276

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Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L++YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 78.9518 bits (193), Expect = 4.894e-15
Identity = 36/87 (41.38%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  ++LR+ F +YG V+D+FIPKPFR FAFVTF   ++AQ L G  + +KG ++ I +A PK   N++L    +F
Sbjct:  190 SRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF 276

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Match: AL109811.3 (novel protein)

HSP 1 Score: 246.899 bits (629), Expect = 7.571e-73
Identity = 121/249 (48.59%), Postives = 167/249 (67.07%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L++YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 78.9518 bits (193), Expect = 4.894e-15
Identity = 36/87 (41.38%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  ++LR+ F +YG V+D+FIPKPFR FAFVTF   ++AQ L G  + +KG ++ I +A PK   N++L    +F
Sbjct:  190 SRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF 276

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: tdp-1 (Tar DNA-binding protein homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:D0VWM8])

HSP 1 Score: 143.28 bits (360), Expect = 2.881e-36
Identity = 86/282 (30.50%), Postives = 145/282 (51.42%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKL--SDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRL-----------------------EGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLA-EKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFE-------QYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQ-SININGITLTIGSAVPKINSNR 887
            D  VL+TTL   FP   GLKY+ P+T   RA+++  S  K   P +GWE+  F+ +    + + +     +    K +++                          +  DLIVL + +K  +E  +KYF   G +V  ++K+ +   +SKG+ F+R +    Q   LA  +H+IDGR C VKVP  +++  +  IS+ I VG  ++++    LR  F        +   VTD+FIPKPFR FAFVT  S++ A+ ++ + S+ +NG+++ +  A P+  +N+
Sbjct:   65 DGVVLMTTLQASFPGATGLKYKNPKTGANRAVQVDPSGLKLIAPADGWENKTFFVIVAPQSERVRALSSADATSAKRRKVGSSDDSDSDDGRDGRSGRKRAVERDSQPVDLIVLGVDFKTTDECFQKYFEDIGTVVFCEIKR-KSDGNSKGFGFVRMSSVGEQNKVLAIPQHMIDGRRCDVKVPDGRDKQGRPSISR-IFVGRLTDKVDEHQLRKVFGDEAKSYIETAVVTDVFIPKPFRGFAFVTLSSAEAAERIVSKGSLTVNGLSVGLSIAQPREENNQ 344

HSP 2 Score: 52.7582 bits (125), Expect = 1.361e-6
Identity = 29/87 (33.33%), Postives = 48/87 (55.17%), Query Frame = -2

Query: 3904 KIHVSYSAEELEMEDLRKAFE-------EYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGR-CVTVKGHTLTIGSAVPKITGNKKL 4140
            +I V    ++++   LRK F        E   V D+FIPKPFR FAFVT   +E A++++ +  +TV G ++ +  A P+   N+ +
Sbjct:  260 RIFVGRLTDKVDEHQLRKVFGDEAKSYIETAVVTDVFIPKPFRGFAFVTLSSAEAAERIVSKGSLTVNGLSVGLSIAQPREENNQSV 346

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: tdp-1 (Tar DNA-binding protein homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:D0VWM8])

HSP 1 Score: 142.895 bits (359), Expect = 4.701e-36
Identity = 89/285 (31.23%), Postives = 146/285 (51.23%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKL--SDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRL-----------------------EGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLA-EKHLIDGRWCAVKVPFSKNEADKQ---EISKKIHVGYASEEISMEDLRIAFE-------QYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQ-SININGITLTIGSAVPKINSNR 887
            D  VL+TTL   FP   GLKY+ P+T   RA+++  S  K   P +GWE+  F+ +    + + +     +    K +++                          +  DLIVL + +K  +E  +KYF   G +V  ++K+ +   +SKG+ F+R +    Q   LA  +H+IDGR C VKVP  ++  DKQ    IS+ I VG  ++++    LR  F        +   VTD+FIPKPFR FAFVT  S++ A+ ++ + S+ +NG+++ +  A P+  +N+
Sbjct:   65 DGVVLMTTLQASFPGATGLKYKNPKTGANRAVQVDPSGLKLIAPADGWENKTFFVIVAPQSERVRALSSADATSAKRRKVGSSDDSDSDDGRDGRSGRKRAVERDSQPVDLIVLGVDFKTTDECFQKYFEDIGTVVFCEIKR-KSDGNSKGFGFVRMSSVGEQNKVLAIPQHMIDGRRCDVKVPDGRSLQDKQGRPSISR-IFVGRLTDKVDEHQLRKVFGDEAKSYIETAVVTDVFIPKPFRGFAFVTLSSAEAAERIVSKGSLTVNGLSVGLSIAQPREENNQ 347

HSP 2 Score: 52.7582 bits (125), Expect = 1.347e-6
Identity = 29/87 (33.33%), Postives = 48/87 (55.17%), Query Frame = -2

Query: 3904 KIHVSYSAEELEMEDLRKAFE-------EYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGR-CVTVKGHTLTIGSAVPKITGNKKL 4140
            +I V    ++++   LRK F        E   V D+FIPKPFR FAFVT   +E A++++ +  +TV G ++ +  A P+   N+ +
Sbjct:  263 RIFVGRLTDKVDEHQLRKVFGDEAKSYIETAVVTDVFIPKPFRGFAFVTLSSAEAAERIVSKGSLTVNGLSVGLSIAQPREENNQSV 349

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: msi-1 (MuSashI (Fly neural) family; Neural RNA-binding protein MSI-1 [Source:UniProtKB/TrEMBL;Acc:G5EFS2])

HSP 1 Score: 84.3445 bits (207), Expect = 4.699e-17
Identity = 54/166 (32.53%), Postives = 82/166 (49.40%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEK-HLIDGRWCAVKVPFSK-NEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSLIGQSIN-INGITLTIGSAVPK 872
            + +  L W+   E LR YF +FGE+    V +D  T  ++G+ FI F D ++    L  + H +DG+    KV F K  +A     +KK+ +G  S   ++ED++  FE YG V D  +      +  R F FVTFDS + A  +     + ING  +    A PK
Sbjct:   47 MFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDPATKRARGFGFITFVDPSSVDKVLNNREHELDGKKIDPKVAFPKRTQAKLVTKTKKVFIGGLSATSTLEDMKQYFETYGKVEDAMLMFDKATQRHRGFGFVTFDSDEVADKVCEIHFHEINGKMVECKKAQPK 212

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Match: sqd-1 (Homologous to Drosophila SQD (Squid) protein [Source:UniProtKB/TrEMBL;Acc:Q8MXR6])

HSP 1 Score: 81.2629 bits (199), Expect = 3.638e-16
Identity = 55/173 (31.79%), Postives = 84/173 (48.55%), Query Frame = 3

Query:  375 LEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEK-HLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIP-----KPFRNFAFVTFDSSDTAQSLIGQSININGI-TLTIGSAVPK 872
             +G +   + V  +  +V+ E L  +F+++GE+   QVK DR    S+G+AF+ F       L LA +   I G+   VK   S+        +KK+ VG    + S +DLR  FEQ+G V DI  P     K  RNFAF+ F+  ++A     Q+    G     +  AVP+
Sbjct:   23 TKGNEDKKIFVGGISPEVNNEDLSSHFTQYGEVAQAQVKYDRTNGRSRGFAFVEFTTGEGCKLALAAREQTIKGKSVEVKPAKSRE-------NKKVFVGGLPSDYSEQDLRSHFEQFGKVDDIEWPFDKQTKARRNFAFIVFEEEESADKASSQTKQTFGTRECDVKKAVPQ 188

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Query:  375 LEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEK-HLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIP-----KPFRNFAFVTFDSSDTAQSLIGQSININGI-TLTIGSAVPK 872
             +G +   + V  +  +V+ E L  +F+++GE+   QVK DR    S+G+AF+ F       L LA +   I G+   VK   S+        +KK+ VG    + S +DLR  FEQ+G V DI  P     K  RNFAF+ F+  ++A     Q+    G     +  AVP+
Sbjct:   23 TKGNEDKKIFVGGISPEVNNEDLSSHFTQYGEVAQAQVKYDRTNGRSRGFAFVEFTTGEGCKLALAAREQTIKGKSVEVKPAKSRE-------NKKVFVGGLPSDYSEQDLRSHFEQFGKVDDIEWPFDKQTKARRNFAFIVFEEEESADKASSQTKQTFGTRECDVKKAVPQ 188

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: TBPH (gene:FBgn0025790 transcript:FBtr0089626)

HSP 1 Score: 250.366 bits (638), Expect = 5.843e-74
Identity = 121/251 (48.21%), Postives = 170/251 (67.73%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKP-VE-GWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGR-KCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNR 887
            D T+LL+TL   FP  CGLKYR  +T   R ++ ++G+ + P VE GW +  ++CVFPK+N KRK D+ +E    K+KR+E R +CTDLIVL L WK  EE+LR+YF  +GE+++ Q+KKD ++  SKG+ F+RF  Y AQ+  L  +HLIDGRWC VKVP SK      ++  K+ VG  +E+I+ +DLR  F ++G VTD+FIP+PFR F+FVTF   D AQSL G+   I G+++ + +A PK   NR
Sbjct:   22 DGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKEN-KRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDGRWCEVKVPNSKGMG--HQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNR 269

HSP 2 Score: 76.6406 bits (187), Expect = 2.449e-14
Identity = 43/131 (32.82%), Postives = 70/131 (53.44%), Query Frame = -2

Query: 3778 QEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQFPICPYNEQGPMTAGRYGWSSYEPA-----PMQSSRYKARQF 4155
             ++  K+ V    E++  +DLR+ F ++G V D+FIP+PFR F+FVTF   +VAQ L G    +KG ++ + +A PK   N+   + +      YN     +A  +G  SY P      P ++  ++ RQF
Sbjct:  188 HQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQS------YNYN---SANSFGMHSYHPQGNHMNPGRNGHHRGRQF 309

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: TBPH (gene:FBgn0025790 transcript:FBtr0089625)

HSP 1 Score: 254.988 bits (650), Expect = 4.365e-73
Identity = 121/252 (48.02%), Postives = 170/252 (67.46%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKP-VE-GWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGR-KCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D T+LL+TL   FP  CGLKYR  +T   R ++ ++G+ + P VE GW +  ++CVFPK+N KRK D+ +E    K+KR+E R +CTDLIVL L WK  EE+LR+YF  +GE+++ Q+KKD ++  SKG+ F+RF  Y AQ+  L  +HLIDGRWC VKVP SK      ++  K+ VG  +E+I+ +DLR  F ++G VTD+FIP+PFR F+FVTF   D AQSL G+   I G+++ + +A PK   NR 
Sbjct:   22 DGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKEN-KRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDGRWCEVKVPNSKGMG--HQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRN 270

HSP 2 Score: 75.485 bits (184), Expect = 2.055e-13
Identity = 41/120 (34.17%), Postives = 65/120 (54.17%), Query Frame = -2

Query: 3835 SEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPA-------QFPICPYNEQGP-MTAGRYG 4170
            S+    ++  K+ V    E++  +DLR+ F ++G V D+FIP+PFR F+FVTF   +VAQ L G    +KG ++ + +A PK   N+   + +        F +  Y+ QG  M  GR G
Sbjct:  183 SKGMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQGNHMNPGRNG 302

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: TBPH (gene:FBgn0025790 transcript:FBtr0089624)

HSP 1 Score: 254.988 bits (650), Expect = 4.365e-73
Identity = 121/252 (48.02%), Postives = 170/252 (67.46%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKP-VE-GWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGR-KCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D T+LL+TL   FP  CGLKYR  +T   R ++ ++G+ + P VE GW +  ++CVFPK+N KRK D+ +E    K+KR+E R +CTDLIVL L WK  EE+LR+YF  +GE+++ Q+KKD ++  SKG+ F+RF  Y AQ+  L  +HLIDGRWC VKVP SK      ++  K+ VG  +E+I+ +DLR  F ++G VTD+FIP+PFR F+FVTF   D AQSL G+   I G+++ + +A PK   NR 
Sbjct:   22 DGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKEN-KRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDGRWCEVKVPNSKGMG--HQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRN 270

HSP 2 Score: 75.485 bits (184), Expect = 2.055e-13
Identity = 41/120 (34.17%), Postives = 65/120 (54.17%), Query Frame = -2

Query: 3835 SEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPA-------QFPICPYNEQGP-MTAGRYG 4170
            S+    ++  K+ V    E++  +DLR+ F ++G V D+FIP+PFR F+FVTF   +VAQ L G    +KG ++ + +A PK   N+   + +        F +  Y+ QG  M  GR G
Sbjct:  183 SKGMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQGNHMNPGRNG 302

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: TBPH (gene:FBgn0025790 transcript:FBtr0089627)

HSP 1 Score: 254.988 bits (650), Expect = 4.365e-73
Identity = 121/252 (48.02%), Postives = 170/252 (67.46%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKP-VE-GWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGR-KCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D T+LL+TL   FP  CGLKYR  +T   R ++ ++G+ + P VE GW +  ++CVFPK+N KRK D+ +E    K+KR+E R +CTDLIVL L WK  EE+LR+YF  +GE+++ Q+KKD ++  SKG+ F+RF  Y AQ+  L  +HLIDGRWC VKVP SK      ++  K+ VG  +E+I+ +DLR  F ++G VTD+FIP+PFR F+FVTF   D AQSL G+   I G+++ + +A PK   NR 
Sbjct:   22 DGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKEN-KRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDGRWCEVKVPNSKGMG--HQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRN 270

HSP 2 Score: 75.485 bits (184), Expect = 2.055e-13
Identity = 41/120 (34.17%), Postives = 65/120 (54.17%), Query Frame = -2

Query: 3835 SEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPA-------QFPICPYNEQGP-MTAGRYG 4170
            S+    ++  K+ V    E++  +DLR+ F ++G V D+FIP+PFR F+FVTF   +VAQ L G    +KG ++ + +A PK   N+   + +        F +  Y+ QG  M  GR G
Sbjct:  183 SKGMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQGNHMNPGRNG 302

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Match: TBPH (gene:FBgn0025790 transcript:FBtr0301643)

HSP 1 Score: 254.988 bits (650), Expect = 4.365e-73
Identity = 121/252 (48.02%), Postives = 170/252 (67.46%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKP-VE-GWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGR-KCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D T+LL+TL   FP  CGLKYR  +T   R ++ ++G+ + P VE GW +  ++CVFPK+N KRK D+ +E    K+KR+E R +CTDLIVL L WK  EE+LR+YF  +GE+++ Q+KKD ++  SKG+ F+RF  Y AQ+  L  +HLIDGRWC VKVP SK      ++  K+ VG  +E+I+ +DLR  F ++G VTD+FIP+PFR F+FVTF   D AQSL G+   I G+++ + +A PK   NR 
Sbjct:   22 DGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVESGWGEYAYFCVFPKEN-KRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDGRWCEVKVPNSKGMG--HQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRN 270

HSP 2 Score: 75.485 bits (184), Expect = 2.055e-13
Identity = 41/120 (34.17%), Postives = 65/120 (54.17%), Query Frame = -2

Query: 3835 SEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPA-------QFPICPYNEQGP-MTAGRYG 4170
            S+    ++  K+ V    E++  +DLR+ F ++G V D+FIP+PFR F+FVTF   +VAQ L G    +KG ++ + +A PK   N+   + +        F +  Y+ QG  M  GR G
Sbjct:  183 SKGMGHQVPCKVFVGRCTEDINSDDLREYFSKFGEVTDVFIPRPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHPQGNHMNPGRNG 302

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Match: tardbp (TAR DNA binding protein [Source:ZFIN;Acc:ZDB-GENE-030131-3777])

HSP 1 Score: 238.039 bits (606), Expect = 1.748e-68
Identity = 112/253 (44.27%), Postives = 165/253 (65.22%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKD----NNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL++R+P +   R ++L DG  + P  GW +L +   +PK+    +NKRK+DE       K KR + +K +DLIVL L WK  E+ L+ YF  FGE+++VQVK+D +T +SKG+ F+RF D+  Q   + ++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG VTD+FIPKPFR FAFVTF     A +L G+ + I G+++ I +A PK N+ R+
Sbjct:   24 DGTVLLSTVSAQFPGACGLRFRSPVSQCMRGVRLVDGILHAPENGWGNLVYVVNYPKETVLPDNKRKMDEIDASSATKIKRGD-QKTSDLIVLGLPWKTSEQDLKDYFGTFGEVIMVQVKRDVKTGNSKGFGFVRFGDWETQSKVMTQRHMIDGRWCDCKLPNSKQGIDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAAALCGEDLIIKGVSVHISNAEPKHNNTRQ 275

HSP 2 Score: 73.9442 bits (180), Expect = 4.128e-13
Identity = 33/81 (40.74%), Postives = 52/81 (64.20%), Query Frame = -2

Query: 3904 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4146
            ++K+ V    E++  ++LR+ F +YG V D+FIPKPFR FAFVTF   +VA  L G  + +KG ++ I +A PK    +++
Sbjct:  196 SRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAAALCGEDLIIKGVSVHISNAEPKHNNTRQM 276

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Match: tardbpl (TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB-GENE-031030-1])

HSP 1 Score: 233.417 bits (594), Expect = 2.678e-68
Identity = 113/246 (45.93%), Postives = 162/246 (65.85%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINS 881
            D TVLL+T+   FP  CGL+YR+P +   R ++L +G  + P   W +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YF  FGE+++VQVK+D ++ +SKG+ F+RF DY  Q+  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG VTD+FIPKPFR FAFVTF     AQSL G+ + I G ++ I +A PK N+
Sbjct:   24 DGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEGVLHAPEADWGNLVYVVNYPKDN-KRKMDEMDAASAVKIKR-GIQKTSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPKHNN 267

HSP 2 Score: 75.0998 bits (183), Expect = 6.071e-14
Identity = 34/74 (45.95%), Postives = 50/74 (67.57%), Query Frame = -2

Query: 3925 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPK 4146
            ++K+ V    E++  ++LR+ F +YG V D+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK
Sbjct:  191 SRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPK 264

[Close]

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINS 881
            D TVLL+T+   FP  CGL+YR+P +   R ++L +G  + P   W +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YF  FGE+++VQVK+D ++ +SKG+ F+RF DY  Q+  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG VTD+FIPKPFR FAFVTF     AQSL G+ + I G ++ I +A PK N+
Sbjct:   24 DGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEGVLHAPEADWGNLVYVVNYPKDN-KRKMDEMDAASAVKIKR-GIQKTSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPKHNN 267

HSP 2 Score: 75.0998 bits (183), Expect = 6.071e-14
Identity = 34/74 (45.95%), Postives = 50/74 (67.57%), Query Frame = -2

Query: 3925 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPK 4146
            ++K+ V    E++  ++LR+ F +YG V D+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK
Sbjct:  191 SRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPK 264

[Close]

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINS 881
            D TVLL+T+   FP  CGL+YR+P +   R ++L +G  + P   W +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YF  FGE+++VQVK+D ++ +SKG+ F+RF DY  Q+  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG VTD+FIPKPFR FAFVTF     AQSL G+ + I G ++ I +A PK N+
Sbjct:   24 DGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEGVLHAPEADWGNLVYVVNYPKDN-KRKMDEMDAASAVKIKR-GIQKTSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPKHNN 267

HSP 2 Score: 75.0998 bits (183), Expect = 6.071e-14
Identity = 34/74 (45.95%), Postives = 50/74 (67.57%), Query Frame = -2

Query: 3925 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPK 4146
            ++K+ V    E++  ++LR+ F +YG V D+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK
Sbjct:  191 SRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPK 264

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Match: tardbp (TAR DNA binding protein [Source:ZFIN;Acc:ZDB-GENE-030131-3777])

HSP 1 Score: 235.343 bits (599), Expect = 1.410e-67
Identity = 113/256 (44.14%), Postives = 167/256 (65.23%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKD----NNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTF---DSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL++R+P +   R ++L DG  + P  GW +L +   +PK+    +NKRK+DE       K KR + +K +DLIVL L WK  E+ L+ YF  FGE+++VQVK+D +T +SKG+ F+RF D+  Q   + ++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG VTD+FIPKPFR FAFVTF    +S  A +L G+ + I G+++ I +A PK N+ R+
Sbjct:   24 DGTVLLSTVSAQFPGACGLRFRSPVSQCMRGVRLVDGILHAPENGWGNLVYVVNYPKETVLPDNKRKMDEIDASSATKIKRGD-QKTSDLIVLGLPWKTSEQDLKDYFGTFGEVIMVQVKRDVKTGNSKGFGFVRFGDWETQSKVMTQRHMIDGRWCDCKLPNSKQGIDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQASHVAAALCGEDLIIKGVSVHISNAEPKHNNTRQ 278

HSP 2 Score: 71.2478 bits (173), Expect = 3.670e-12
Identity = 34/84 (40.48%), Postives = 53/84 (63.10%), Query Frame = -2

Query: 3904 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTF---ELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4146
            ++K+ V    E++  ++LR+ F +YG V D+FIPKPFR FAFVTF   + S VA  L G  + +KG ++ I +A PK    +++
Sbjct:  196 SRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQASHVAAALCGEDLIIKGVSVHISNAEPKHNNTRQM 279

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: jarid2 (jumonji and AT-rich interaction domain containing 2 [Source:Xenbase;Acc:XB-GENE-982166])

HSP 1 Score: 253.062 bits (645), Expect = 1.516e-73
Identity = 133/270 (49.26%), Postives = 179/270 (66.30%), Query Frame = 3

Query:   81 MYYIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            M YI V E E  E +EIP E+D TVLL+T+   FP  CGL+YR P     R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR    K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RFADY  QV  ++++H+IDGRWC  K+P SK+  D+   S+K+ VG  +E++S E+LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I G+++ + +A PK N+NR+
Sbjct:   12 MEYIRVAEDENEEPMEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVNQCMRGVRLVEGILHAPENGWGNLVYVVNYPKDN-KRKMDETDASSAVKIKRAV-TKTSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKKDAKTGHSKGFGFVRFADYETQVKVMSQRHMIDGRWCDCKLPNSKS-PDEPMRSRKVFVGRCTEDMSAEELRQFFSQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGVSVHVSTAEPKHNNNRQ 278

HSP 2 Score: 88.9669 bits (219), Expect = 9.418e-18
Identity = 41/96 (42.71%), Postives = 61/96 (63.54%), Query Frame = -2

Query: 3859 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQFPICPYNEQG 4146
            ++K+ V    E++  E+LR+ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ + +A PK   N++L    +FP   +  QG
Sbjct:  199 SRKVFVGRCTEDMSAEELRQFFSQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGVSVHVSTAEPKHNNNRQLERGGRFPGPSFGNQG 294

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: jarid2 (jumonji and AT-rich interaction domain containing 2 [Source:Xenbase;Acc:XB-GENE-982166])

HSP 1 Score: 172.555 bits (436), Expect = 1.928e-46
Identity = 91/182 (50.00%), Postives = 119/182 (65.38%), Query Frame = 3

Query:   81 MYYIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSK 626
            M YI V E E  E +EIP E+D TVLL+T+   FP  CGL+YR P     R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR    K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RFADY  QV  ++++H+IDGRWC  K+P SK
Sbjct:    3 MEYIRVAEDENEEPMEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVNQCMRGVRLVEGILHAPENGWGNLVYVVNYPKDN-KRKMDETDASSAVKIKRAV-TKTSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKKDAKTGHSKGFGFVRFADYETQVKVMSQRHMIDGRWCDCKLPNSK 182

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: kcnj4 (potassium inwardly rectifying channel subfamily J member 4 [Source:Xenbase;Acc:XB-GENE-493748])

HSP 1 Score: 83.5741 bits (205), Expect = 2.074e-16
Identity = 49/145 (33.79%), Postives = 74/145 (51.03%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHL-IDGRWCAVKVPFSKNEADKQEI-SKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSL 812
            + +  L W+   ++LR YF+KFGE+    V +D  T  S+G+ F+ FAD A+    LA+ H  +D +    KV F +    K    +KKI VG  S    +ED++  FEQ+G V D  +         R F FVTF+  D  + +
Sbjct:   23 MFIGGLSWQTSPDSLRDYFNKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFEIEDVVEKV 167

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: kcnj4 (potassium inwardly rectifying channel subfamily J member 4 [Source:Xenbase;Acc:XB-GENE-493748])

HSP 1 Score: 83.5741 bits (205), Expect = 2.569e-16
Identity = 49/145 (33.79%), Postives = 74/145 (51.03%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHL-IDGRWCAVKVPFSKNEADKQEI-SKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSL 812
            + +  L W+   ++LR YF+KFGE+    V +D  T  S+G+ F+ FAD A+    LA+ H  +D +    KV F +    K    +KKI VG  S    +ED++  FEQ+G V D  +         R F FVTF+  D  + +
Sbjct:   23 MFIGGLSWQTSPDSLRDYFNKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFEIEDVVEKV 167

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Match: kcnj4 (potassium inwardly rectifying channel subfamily J member 4 [Source:Xenbase;Acc:XB-GENE-493748])

HSP 1 Score: 83.9593 bits (206), Expect = 2.781e-16
Identity = 49/145 (33.79%), Postives = 74/145 (51.03%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHL-IDGRWCAVKVPFSKNEADKQEI-SKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSL 812
            + +  L W+   ++LR YF+KFGE+    V +D  T  S+G+ F+ FAD A+    LA+ H  +D +    KV F +    K    +KKI VG  S    +ED++  FEQ+G V D  +         R F FVTF+  D  + +
Sbjct:   23 MFIGGLSWQTSPDSLRDYFNKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLAQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFEIEDVVEKV 167

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 245.743 bits (626), Expect = 7.918e-73
Identity = 121/249 (48.59%), Postives = 166/249 (66.67%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ E+L+  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 79.337 bits (194), Expect = 2.196e-15
Identity = 38/87 (43.68%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  E+L++ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK   N++L    +F
Sbjct:  190 SRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF 276

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 245.743 bits (626), Expect = 1.184e-72
Identity = 121/249 (48.59%), Postives = 166/249 (66.67%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ E+L+  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 79.337 bits (194), Expect = 2.765e-15
Identity = 38/87 (43.68%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  E+L++ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK   N++L    +F
Sbjct:  190 SRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF 276

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 245.743 bits (626), Expect = 1.184e-72
Identity = 121/249 (48.59%), Postives = 166/249 (66.67%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ E+L+  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 79.337 bits (194), Expect = 2.765e-15
Identity = 38/87 (43.68%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  E+L++ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK   N++L    +F
Sbjct:  190 SRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF 276

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 245.743 bits (626), Expect = 1.184e-72
Identity = 121/249 (48.59%), Postives = 166/249 (66.67%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ E+L+  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 79.337 bits (194), Expect = 2.765e-15
Identity = 38/87 (43.68%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  E+L++ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK   N++L    +F
Sbjct:  190 SRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF 276

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Match: Tardbp (TAR DNA binding protein [Source:MGI Symbol;Acc:MGI:2387629])

HSP 1 Score: 245.743 bits (626), Expect = 1.184e-72
Identity = 121/249 (48.59%), Postives = 166/249 (66.67%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ E+L+  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 79.337 bits (194), Expect = 2.765e-15
Identity = 38/87 (43.68%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  E+L++ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK   N++L    +F
Sbjct:  190 SRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRF 276

[Close]

BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q28F51|TADBP_XENTR (TAR DNA-binding protein 43 OS=Xenopus tropicalis OX=8364 GN=tardbp PE=2 SV=1)

HSP 1 Score: 253.062 bits (645), Expect = 7.247e-73
Identity = 133/270 (49.26%), Postives = 179/270 (66.30%), Query Frame = 3

Query:   81 MYYIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            M YI V E E  E +EIP E+D TVLL+T+   FP  CGL+YR P     R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR    K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RFADY  QV  ++++H+IDGRWC  K+P SK+  D+   S+K+ VG  +E++S E+LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I G+++ + +A PK N+NR+
Sbjct:    3 MEYIRVAEDENEEPMEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVNQCMRGVRLVEGILHAPENGWGNLVYVVNYPKDN-KRKMDETDASSAVKIKRAV-TKTSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKKDAKTGHSKGFGFVRFADYETQVKVMSQRHMIDGRWCDCKLPNSKS-PDEPMRSRKVFVGRCTEDMSAEELRQFFSQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGVSVHVSTAEPKHNNNRQ 269

HSP 2 Score: 88.9669 bits (219), Expect = 4.510e-17
Identity = 41/96 (42.71%), Postives = 61/96 (63.54%), Query Frame = -2

Query: 3859 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQFPICPYNEQG 4146
            ++K+ V    E++  E+LR+ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ + +A PK   N++L    +FP   +  QG
Sbjct:  190 SRKVFVGRCTEDMSAEELRQFFSQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGVSVHVSTAEPKHNNNRQLERGGRFPGPSFGNQG 285

[Close]

BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q5R5W2|TADBP_PONAB (TAR DNA-binding protein 43 OS=Pongo abelii OX=9601 GN=TARDBP PE=2 SV=1)

HSP 1 Score: 251.521 bits (641), Expect = 2.901e-72
Identity = 121/249 (48.59%), Postives = 167/249 (67.07%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L++YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 80.1073 bits (196), Expect = 3.857e-14
Identity = 35/81 (43.21%), Postives = 55/81 (67.90%), Query Frame = -2

Query: 3904 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4146
            ++K+ V    E++  ++LR+ F +YG V+D+FIPKPFR FAFVTF   ++AQ L G  + +KG ++ I +A PK   N++L
Sbjct:  190 SRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQL 270

[Close]

BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q13148|TADBP_HUMAN (TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1)

HSP 1 Score: 251.521 bits (641), Expect = 3.015e-72
Identity = 121/249 (48.59%), Postives = 167/249 (67.07%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L++YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++LR  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 80.1073 bits (196), Expect = 3.823e-14
Identity = 35/81 (43.21%), Postives = 55/81 (67.90%), Query Frame = -2

Query: 3904 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4146
            ++K+ V    E++  ++LR+ F +YG V+D+FIPKPFR FAFVTF   ++AQ L G  + +KG ++ I +A PK   N++L
Sbjct:  190 SRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQL 270

[Close]

BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q921F2|TADBP_MOUSE (TAR DNA-binding protein 43 OS=Mus musculus OX=10090 GN=Tardbp PE=1 SV=1)

HSP 1 Score: 249.595 bits (636), Expect = 1.292e-71
Identity = 121/249 (48.59%), Postives = 166/249 (66.67%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +   R ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVKKD +T HSKG+ F+RF +Y  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ E+L+  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 80.1073 bits (196), Expect = 3.373e-14
Identity = 37/81 (45.68%), Postives = 55/81 (67.90%), Query Frame = -2

Query: 3904 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4146
            ++K+ V    E++  E+L++ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK   N++L
Sbjct:  190 SRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQL 270

[Close]

BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Match: sp|Q5ZLN5|TADBP_CHICK (TAR DNA-binding protein 43 OS=Gallus gallus OX=9031 GN=TARDBP PE=2 SV=1)

HSP 1 Score: 248.44 bits (633), Expect = 3.517e-71
Identity = 120/249 (48.19%), Postives = 166/249 (66.67%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR P +     ++L +G  + P  GW +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L++YFS FGE+++VQVKKD +T HSKG+ F+RF DY  QV  ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ ++L+  F QYG V D+FIPKPFR FAFVTF     AQSL G+ + I GI++ I +A PK NSNR+
Sbjct:   23 DGTVLLSTVTAQFPGACGLRYRNPVSQCMWGVRLVEGILHAPEAGWGNLVYVVNYPKDN-KRKMDETDASSAVKVKRAV-QKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDIKTGHSKGFGFVRFTDYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTADELQQFFAQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGISVHISNAEPKHNSNRQ 269

HSP 2 Score: 79.7221 bits (195), Expect = 4.449e-14
Identity = 36/81 (44.44%), Postives = 55/81 (67.90%), Query Frame = -2

Query: 3904 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4146
            ++K+ V    E++  ++L++ F +YG VVD+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK   N++L
Sbjct:  190 SRKVFVGRCTEDMTADELQQFFAQYGEVVDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGISVHISNAEPKHNSNRQL 270

[Close]

BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A4E0RSY0 (TAR DNA-binding protein 43 OS=Fasciola hepatica OX=6192 GN=D915_009315 PE=4 SV=1)

HSP 1 Score: 311.997 bits (798), Expect = 3.090e-91
Identity = 148/269 (55.02%), Postives = 197/269 (73.23%), Query Frame = 3

Query:   87 YIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPV-EGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            YI VCE +    +E+P+E+D T+LL TL   FP   GLKY+APE+  FR L+L+D   Y P   GW D  F+CVFPK  +KRK +   +   QK KRLEGRKCTDLIVLNL W  DE+TLR+YFS FGE+V+VQ+K+D +T+ S+GY F+RF+DYAAQV+CLAE+H+ID R C V++P SK E D+QE+ +KIHVG  +E++  + LR  F +YG V D+FIP+PFR+FAFVTFD  D A  L+G+ + I+G  +TIGSAVPK+  N++
Sbjct:    6 YIRVCEDDGEIPVELPLEQDGTLLLATLTAQFPRCTGLKYKAPESGCFRGLRLADDHIYPPSGSGWSDTDFFCVFPKAESKRKAEGSEDDSTQKVKRLEGRKCTDLIVLNLSWNTDEDTLREYFSGFGEVVMVQLKRDLKTNKSRGYGFVRFSDYAAQVMCLAERHMIDNRLCDVRIPNSKVEGDRQEVGRKIHVGNLTEDVGSDVLRQFFSEYGRVIDVFIPRPFRSFAFVTFDDPDVASGLMGKDLVIHGCRVTIGSAVPKLPQNKQ 274

HSP 2 Score: 101.679 bits (252), Expect = 8.876e-19
Identity = 45/88 (51.14%), Postives = 65/88 (73.86%), Query Frame = -2

Query: 3904 EADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4167
            E D+QE+ +KIHV    E++  + LR+ F EYG V+D+FIP+PFR+FAFVTF+  +VA  L+G+ + + G  +TIGSAVPK+  NK+L
Sbjct:  188 EGDRQEVGRKIHVGNLTEDVGSDVLRQFFSEYGRVIDVFIPRPFRSFAFVTFDDPDVASGLMGKDLVIHGCRVTIGSAVPKLPQNKQL 275

[Close]

BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A504Z4S8 (TAR DNA-binding protein 43 OS=Fasciola gigantica OX=46835 GN=FGIG_02376 PE=4 SV=1)

HSP 1 Score: 310.071 bits (793), Expect = 3.472e-91
Identity = 149/263 (56.65%), Postives = 198/263 (75.29%), Query Frame = 3

Query:   87 YIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKI 875
            YI V E +E   IE+P+E D +VLLTTL G+FP   GLKY AP++  +R ++L+DGK Y P EGW    + CVFPK + KRK DE+ +    KSK+LEG+KCTDLIVLNL WK DE  LR YFS++GELV+VQVK+   T  SKGY FIRF++Y +Q +CLAE+H IDGRWC V+VP SK E DKQE+S+K+HVG  +E+++ + LR  F Q+G V D+F+PKPFR+FAFVTF+ ++TA  L+G+ ++I+G  +TIGSAVPK+
Sbjct:    6 YIRVSEDDEESPIEVPIETDGSVLLTTLNGVFPKATGLKYMAPDSGCYRGVRLNDGKLYAPDEGWVH-TYVCVFPKSDKKRKGDEDQDSLSAKSKKLEGKKCTDLIVLNLAWKTDEAALRDYFSRYGELVMVQVKRHPGTQQSKGYGFIRFSEYESQPMCLAERHYIDGRWCDVRVPMSKLEGDKQEVSRKVHVGGVTEKMTADTLREYFLQFGQVLDVFVPKPFRSFAFVTFEDAETAAGLLGKELSIDGSKVTIGSAVPKL 267

HSP 2 Score: 97.4413 bits (241), Expect = 1.193e-17
Identity = 41/82 (50.00%), Postives = 63/82 (76.83%), Query Frame = -2

Query: 3922 EADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKI 4167
            E DKQE+++K+HV    E++  + LR+ F ++G V+D+F+PKPFR+FAFVTFE +E A  L+G+ +++ G  +TIGSAVPK+
Sbjct:  186 EGDKQEVSRKVHVGGVTEKMTADTLREYFLQFGQVLDVFVPKPFRSFAFVTFEDAETAAGLLGKELSIDGSKVTIGSAVPKL 267

[Close]

BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A2H1BSY3 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_15054 PE=4 SV=1)

HSP 1 Score: 309.301 bits (791), Expect = 6.321e-91
Identity = 150/263 (57.03%), Postives = 197/263 (74.90%), Query Frame = 3

Query:   87 YIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKI 875
            YI V E +E   IEIP+E D +VLLTTL G+FP   GLKY AP++  +R ++L+DGK Y P EGW    + CVFPK + KRK DE+ +    KSK+LEG+KCTDLIVLNL WK DE  LR YFS++GELV+VQVK+   T  SKGY FIRF++Y +Q +CLAE+H IDGRWC V+VP SK E DKQE+S+K+HVG  +E+++ + LR  F Q+G V D+F+PKPFR+FAFVTF+ ++TA  L+G+ + I+G  +TIGSAVPK+
Sbjct:    6 YIRVSEDDEESPIEIPIETDGSVLLTTLNGVFPKATGLKYMAPDSGCYRGVRLNDGKLYAPDEGWVH-TYVCVFPKSDKKRKGDEDQDSLSAKSKKLEGKKCTDLIVLNLAWKTDEAALRDYFSRYGELVMVQVKRHPGTQQSKGYGFIRFSEYESQPMCLAERHYIDGRWCDVRVPMSKLEGDKQEVSRKVHVGGVTEKMTADALREYFLQFGQVLDVFVPKPFRSFAFVTFEDAETAAGLLGKELTIDGSKVTIGSAVPKL 267

HSP 2 Score: 98.5969 bits (244), Expect = 5.459e-18
Identity = 42/82 (51.22%), Postives = 63/82 (76.83%), Query Frame = -2

Query: 3922 EADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKI 4167
            E DKQE+++K+HV    E++  + LR+ F ++G V+D+F+PKPFR+FAFVTFE +E A  L+G+ +T+ G  +TIGSAVPK+
Sbjct:  186 EGDKQEVSRKVHVGGVTEKMTADALREYFLQFGQVLDVFVPKPFRSFAFVTFEDAETAAGLLGKELTIDGSKVTIGSAVPKL 267

[Close]

BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A504YT28 (TAR DNA-binding protein 43 OS=Fasciola gigantica OX=46835 GN=FGIG_10236 PE=4 SV=1)

HSP 1 Score: 308.531 bits (789), Expect = 5.612e-90
Identity = 140/250 (56.00%), Postives = 184/250 (73.60%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPV-EGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D T+LL TL   FP   GLKY+APE+  FR L+L+D   Y P   GW D  F+CVFPK  +KRK +   +   QK KRLEGRKCTDLIVLNL W  DE+TLR+YFS FGE+V+VQ+K+D +T+ S+GY F+RF+DYAAQV+CLAE+H+ID R C V++P SK E D+QE+ +KIHVG  +E++  + LR  F +YG V D+FIP+PFR+FAFVTFD  D A  L+G+ + I+G  +TIGSAVPK+  N++
Sbjct:   25 DGTLLLATLTAQFPRCTGLKYKAPESGCFRGLRLADDHIYPPSGSGWSDTDFFCVFPKAESKRKAEGSEDDSTQKVKRLEGRKCTDLIVLNLSWNTDEDTLREYFSGFGEVVMVQLKRDLKTNKSRGYGFVRFSDYAAQVMCLAERHMIDNRLCDVRIPNSKVEGDRQEVGRKIHVGNLTEDVGSDVLRQFFSEYGRVIDVFIPRPFRSFAFVTFDDPDVASGLMGKDLVIHGCRVTIGSAVPKLPQNKQ 274

HSP 2 Score: 101.679 bits (252), Expect = 9.463e-19
Identity = 45/88 (51.14%), Postives = 65/88 (73.86%), Query Frame = -2

Query: 3904 EADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4167
            E D+QE+ +KIHV    E++  + LR+ F EYG V+D+FIP+PFR+FAFVTF+  +VA  L+G+ + + G  +TIGSAVPK+  NK+L
Sbjct:  188 EGDRQEVGRKIHVGNLTEDVGSDVLRQFFSEYGRVIDVFIPRPFRSFAFVTFDDPDVASGLMGKDLVIHGCRVTIGSAVPKLPQNKQL 275

[Close]

BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Match: A0A1S8WSG9 (Uncharacterized protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_06808 PE=4 SV=1)

HSP 1 Score: 306.605 bits (784), Expect = 3.273e-89
Identity = 163/315 (51.75%), Postives = 207/315 (65.71%), Query Frame = 3

Query:   81 MYYIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKXXXXXXXXXXXXXXHYPMYGDNMQSAQGYQTRYAP--GMIPTYGA 1019
            + Y  +CE E +E +E+PVE D T+LL TL   FP   GLKY++ ++  FR L+L     Y PVE   D  FYCVFPKD  KRK DE+ E   QK K LEGRKCTDLIVLNL W+ DE  LR YFS+FG+LV+VQ+KKD +T  S+GY F+RF+DY+ Q +CLAE+H+IDGR C V++P SK E D+QE+S+KIHVG   E I  + LR  F QYG V D+FIPKPFR+FAFVTFD  D A SL+G+ + I G  +TIGSAVPK+ S+ +         G     YP  G  M     + + ++P  GM P  GA
Sbjct:    4 VVYARICEEEGTEPVELPVEADGTLLLPTLTAQFPKCTGLKYKSEDSGCFRGLRLVGDHIYPPVETDWDNVFYCVFPKDK-KRKGDEDTEDTKQKVKCLEGRKCTDLIVLNLAWQTDETKLRNYFSQFGDLVMVQIKKDPDTGKSRGYGFVRFSDYSGQAMCLAERHMIDGRLCDVRIPLSKQEGDRQEVSRKIHVGNLPESIGADALRQHFLQYGLVIDVFIPKPFRSFAFVTFDDPDVAASLLGKDLTIQGHKVTIGSAVPKLPSHVRQNPAFENAGGNLRSPYP--GSPMAHGPLWNSPWSPALGMFPGGGA 315

HSP 2 Score: 105.145 bits (261), Expect = 7.872e-20
Identity = 45/86 (52.33%), Postives = 66/86 (76.74%), Query Frame = -2

Query: 3922 LMQSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKI 4179
            L + E D+QE+++KIHV    E +  + LR+ F +YG V+D+FIPKPFR+FAFVTF+  +VA  L+G+ +T++GH +TIGSAVPK+
Sbjct:  182 LSKQEGDRQEVSRKIHVGNLPESIGADALRQHFLQYGLVIDVFIPKPFRSFAFVTFDDPDVAASLLGKDLTIQGHKVTIGSAVPKL 267

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: tardbp (TAR DNA-binding protein 43-like [Source:NCBI gene;Acc:103044966])

HSP 1 Score: 240.736 bits (613), Expect = 1.218e-69
Identity = 116/252 (46.03%), Postives = 168/252 (66.67%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKD----NNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNR 887
            D TVLL+T+   FP  CGL+YR+P +   R ++L +G  + P  GW +L +   +PK+    +NKRK+DE IE    K KR +  K +DLIVL L WK  E+ L+ YFS FGE+++VQVK+D +T +SKG+ F+RF ++  Q   +A++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ +DLR  F QYG VTD+FIPKPFR FAFVTF     A SL G+ + + G+++ I +A PK N++R
Sbjct:   24 DGTVLLSTVSAQFPGACGLRYRSPISQCMRGVRLVEGVLHAPENGWGNLVYVVNYPKEPALPDNKRKMDE-IEASSAKMKRGD-HKTSDLIVLGLPWKTSEQDLKDYFSTFGEVIMVQVKRDVKTGNSKGFGFVRFGEWETQSKVIAQRHMIDGRWCDCKLPNSKQGPDEPMRSRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVASSLCGEDLIVKGVSVHISNAEPKHNNSR 273

HSP 2 Score: 76.6406 bits (187), Expect = 5.596e-14
Identity = 35/74 (47.30%), Postives = 49/74 (66.22%), Query Frame = -2

Query: 3925 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPK 4146
            ++K+ V    E++  +DLR+ F +YG V D+FIPKPFR FAFVTF   +VA  L G  + VKG ++ I +A PK
Sbjct:  195 SRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVASSLCGEDLIVKGVSVHISNAEPK 268

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: tardbpl (TAR DNA binding protein [Source:NCBI gene;Acc:103025275])

HSP 1 Score: 238.81 bits (608), Expect = 5.150e-69
Identity = 117/254 (46.06%), Postives = 166/254 (65.35%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSK-----NEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL+YR+P +   R ++L +G  + P   W +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVK+D +T +SKG+ F+RF DY  Q+  ++++H+IDGRWC  K+P SK        D+   S+K+ VG  +E+++ +DLR  F QYG VTD+FIPKPFR FAFVTF     AQSL G+ + I G ++ I +A PK N++R+
Sbjct:   24 DGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEGVLHAPDADWGNLVYVVNYPKDN-KRKMDEMDAASAVKIKR-GIQKTSDLIVLGLPWKTSEQDLKDYFSTFGEVIMVQVKRDVKTGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKYFLEQAGPDEPMRSRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPKHNNSRQ 275

HSP 2 Score: 83.9593 bits (206), Expect = 2.138e-16
Identity = 39/93 (41.94%), Postives = 60/93 (64.52%), Query Frame = -2

Query: 3904 FLMQSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKL 4182
            FL Q+  D+   ++K+ V    E++  +DLR+ F +YG V D+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK   ++++
Sbjct:  184 FLEQAGPDEPMRSRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPKHNNSRQM 276

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: tardbpl (TAR DNA binding protein [Source:NCBI gene;Acc:103025275])

HSP 1 Score: 231.491 bits (589), Expect = 1.103e-67
Identity = 116/251 (46.22%), Postives = 163/251 (64.94%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSK-----NEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINS 881
            D TVLL+T+   FP  CGL+YR+P +   R ++L +G  + P   W +L +   +PKDN KRK+DE       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVK+D +T +SKG+ F+RF DY  Q+  ++++H+IDGRWC  K+P SK        D+   S+K+ VG  +E+++ +DLR  F QYG VTD+FIPKPFR FAFVTF     AQSL G+ + I G ++ I +A PK N+
Sbjct:   24 DGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEGVLHAPDADWGNLVYVVNYPKDN-KRKMDEMDAASAVKIKR-GIQKTSDLIVLGLPWKTSEQDLKDYFSTFGEVIMVQVKRDVKTGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKYFLEQAGPDEPMRSRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPKHNN 272

HSP 2 Score: 81.2629 bits (199), Expect = 5.670e-16
Identity = 39/86 (45.35%), Postives = 56/86 (65.12%), Query Frame = -2

Query: 3925 FLMQSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPK 4182
            FL Q+  D+   ++K+ V    E++  +DLR+ F +YG V D+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK
Sbjct:  184 FLEQAGPDEPMRSRKVFVGRCTEDMTADDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPK 269

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: msi2b (RNA-binding protein Musashi homolog 2 [Source:NCBI gene;Acc:103023867])

HSP 1 Score: 87.8113 bits (216), Expect = 3.026e-18
Identity = 50/148 (33.78%), Postives = 76/148 (51.35%), Query Frame = 3

Query:  390 CTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHL-IDGRWCAVKVPFSKNEADKQEI-SKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSL 812
            C+ + +  L W+   ++LR YFSKFGE+    V +D  T  S+G+ F+ FAD A+    L + H  +D +    KV F +    K    +KKI VG  S    +ED++  FEQ+G V D  +         R F FVTF++ D  + +
Sbjct:   16 CSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADAASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKV 163

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Match: msi2b (RNA-binding protein Musashi homolog 2 [Source:NCBI gene;Acc:103023867])

HSP 1 Score: 88.1965 bits (217), Expect = 3.880e-18
Identity = 50/148 (33.78%), Postives = 76/148 (51.35%), Query Frame = 3

Query:  390 CTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHL-IDGRWCAVKVPFSKNEADKQEI-SKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSL 812
            C+ + +  L W+   ++LR YFSKFGE+    V +D  T  S+G+ F+ FAD A+    L + H  +D +    KV F +    K    +KKI VG  S    +ED++  FEQ+G V D  +         R F FVTF++ D  + +
Sbjct:   16 CSKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADAASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKV 163

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009806.1 (pep scaffold:Pmarinus_7.0:GL479354:9188:12030:-1 gene:ENSPMAG00000008859.1 transcript:ENSPMAT00000009806.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 218.009 bits (554), Expect = 3.147e-63
Identity = 111/252 (44.05%), Postives = 151/252 (59.92%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKD------NNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSK---NEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPK 872
            D T+L++ +   FP   GL+YR P+  +FR ++L DG  + P  GW    FY  FPKD       NKRK++E       K  R E R  +DL+VL L W   E+ L+ YFS FG +VL Q+K D  T  SKGY F+RFAD+ +Q+  +  +H+I GRWC  K+P SK    + D+     +I VG   E+I+ EDLR  F Q+G VTD++IPKPFR+F FVTF +   AQSL GQ + + G ++ I SA PK
Sbjct:   23 DGTLLVSNVAAQFPGAVGLRYRPPDAQSFRGVRLVDGVLHPPENGWASYTFYVNFPKDPCVLGLENKRKMEEVDMASASKMLRSEPR-VSDLVVLGLPWTTTEDELKDYFSAFGSVVLSQIKTDPATGKSKGYGFVRFADHESQLKAMGMRHMIGGRWCDAKLPQSKMYPTDPDRN----RIFVGRCPEDITPEDLRSFFGQFGDVTDVYIPKPFRSFGFVTFANEHVAQSLCGQDVIVKGASVHIASAEPK 269

HSP 2 Score: 74.7146 bits (182), Expect = 2.396e-14
Identity = 36/72 (50.00%), Postives = 47/72 (65.28%), Query Frame = -2

Query: 3925 KIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPK 4140
            +I V    E++  EDLR  F ++G V D++IPKPFR+F FVTF    VAQ L G+ V VKG ++ I SA PK
Sbjct:  198 RIFVGRCPEDITPEDLRSFFGQFGDVTDVYIPKPFRSFGFVTFANEHVAQSLCGQDVIVKGASVHIASAEPK 269

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: TARDBP (TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571])

HSP 1 Score: 186.037 bits (471), Expect = 9.252e-54
Identity = 94/191 (49.21%), Postives = 126/191 (65.97%), Query Frame = 3

Query:  318 NNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEI-SKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNR 887
            +NKRK+DE     + K KR   +K +DLIVL L WK  E+ +R YFS FGE+++ QVK+D +T +SKG+ F+RF DY  Q+  LA++H+IDGRWC  K+P SK +       S+KI VG  +E+I+ +DLR  F Q+G VTD+FIPKPFR FAFVTF     AQ L G+ + I G ++ I SA PK    R
Sbjct:    1 DNKRKMDEAEMSNVAKVKR-SVQKTSDLIVLGLPWKASEQDIRDYFSTFGEVLMAQVKRDIKTGNSKGFGFVRFRDYETQLKVLAQRHMIDGRWCDCKLPNSKEQQVGDAFRSRKIFVGRCTEDITADDLRQFFSQFGEVTDVFIPKPFRAFAFVTFSDDQIAQGLCGEDLIIKGTSVHISSAEPKFGYAR 190

HSP 2 Score: 77.7962 bits (190), Expect = 3.825e-16
Identity = 35/75 (46.67%), Postives = 50/75 (66.67%), Query Frame = -2

Query: 3922 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKI 4146
            ++KI V    E++  +DLR+ F ++G V D+FIPKPFR FAFVTF   ++AQ L G  + +KG ++ I SA PK 
Sbjct:  112 SRKIFVGRCTEDITADDLRQFFSQFGEVTDVFIPKPFRAFAFVTFSDDQIAQGLCGEDLIIKGTSVHISSAEPKF 186

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007723.1 (pep scaffold:Pmarinus_7.0:GL496487:1152:2091:-1 gene:ENSPMAG00000006977.1 transcript:ENSPMAT00000007723.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 104.375 bits (259), Expect = 9.459e-27
Identity = 47/103 (45.63%), Postives = 76/103 (73.79%), Query Frame = 3

Query:  318 NNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSK 626
            +NKRK+DE     + K KR   +K +DLIVL L WK +E+ LR YF++ G++++VQVK+D ++  SKG+ F+RF+++ +Q+  ++++HLI GRWC VK+P +K
Sbjct:    1 DNKRKMDESDAWNVAKIKR-SVQKTSDLIVLGLPWKCNEQDLRDYFTEVGDVLMVQVKRDAKSGTSKGFGFVRFSEFESQLKAISQRHLIGGRWCDVKLPNTK 102

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004893.1 (pep scaffold:Pmarinus_7.0:GL479484:4:2056:-1 gene:ENSPMAG00000004449.1 transcript:ENSPMAT00000004893.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 1.364e-15
Identity = 55/168 (32.74%), Postives = 84/168 (50.00%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCL-AEKHLIDGRWCAVKVPFSKNEADK--QEIS-KKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSLIGQSIN-INGITLTIGSAVPK 872
            L V  L ++  EE LR+YF ++G L    V KD ++  S+G+ F+ F+  +     + A  H IDGR    K   S+ ++ +    +S KKI VG   ++   E LR  FE+YG +  + +         R FAFVTF+  D    ++ Q  + ING    I  A+PK
Sbjct:   13 LFVGGLSFETTEEGLRQYFEQWGSLTDCVVMKDTQSKRSRGFGFVTFSSMSEVDAAMSARPHKIDGRMVEPKRAVSREDSMRPGAHLSVKKIFVGGIKDDTDEEHLRDYFEKYGRIEIVEVMTERESGKKRGFAFVTFNDHDPVDKIVVQKYHTINGHNCEIRKALPK 180

HSP 2 Score: 53.1434 bits (126), Expect = 9.336e-8
Identity = 24/70 (34.29%), Postives = 40/70 (57.14%), Query Frame = 3

Query:  426 VDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADY-AAQVLCLAEKHLIDGRWCAVKVPFSKNE 632
             DEE LR YF K+G + +V+V  +RE+   +G+AF+ F D+     + + + H I+G  C ++    K E
Sbjct:  113 TDEEHLRDYFEKYGRIEIVEVMTERESGKKRGFAFVTFNDHDPVDKIVVQKYHTINGHNCEIRKALPKQE 182

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Match: HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:HGNC:5033])

HSP 1 Score: 64.3142 bits (155), Expect = 2.133e-11
Identity = 50/167 (29.94%), Postives = 78/167 (46.71%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCL-AEKHLIDGRWCAVK--VPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYV--TDIFIPKPF---RNFAFVTFDSSDTAQSLIGQSIN-INGITLTIGSAVPK 872
            L +  L ++  EE+LR+Y+ ++G +V   V KD  +  S+G+ FI ++        + A  H +DGR    K  VP   +    Q   KK+ VG   +      LR  F ++G V   D+   K     R FAFVTFD  D    ++ Q  + IN   L +  A+ +
Sbjct:   16 LFIGGLSFETTEESLREYYEQWGTIVDCVVMKDPSSKRSRGFGFITYSVMEEVNSAMQARPHTVDGRVVEAKRAVPRDDSRPGIQVTVKKLFVGGIKDNTDESHLRDYFSKFGRVESVDMVTDKQTGKKRGFAFVTFDDYDPVDQIVFQKFHTINCHKLEVRKALSR 182

HSP 2 Score: 48.1358 bits (113), Expect = 5.381e-6
Identity = 26/87 (29.89%), Postives = 45/87 (51.72%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADY-AAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISK 656
            L V  +    DE  LR YFSKFG +  V +  D++T   +G+AF+ F DY     +   + H I+     V+   S++E +  ++++
Sbjct:  106 LFVGGIKDNTDESHLRDYFSKFGRVESVDMVTDKQTGKKRGFAFVTFDDYDPVDQIVFQKFHTINCHKLEVRKALSRHEMETMQMNQ 192

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Yeast
Match: HRP1 (Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483])

HSP 1 Score: 77.0258 bits (188), Expect = 8.360e-15
Identity = 46/177 (25.99%), Postives = 87/177 (49.15%), Query Frame = 3

Query:  360 QKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTD--IFIPKPF---RNFAFVTFDSSDTAQSLI-GQSININGITLTIGSAVPK 872
            ++SK    ++   + +  L W   E+ LR+YF K+G +  +++ KD  T  S+G+ F+ F   ++    +  +H++DG+    K    ++E DK   + KI VG    ++  ++    F Q+G + D  + + K     R F FVT+DS+D    +   + I+     + I  A P+
Sbjct:  148 ERSKADLSKESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKTQHILDGKVIDPKRAIPRDEQDK---TGKIFVGGIGPDVRPKEFEEFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQNKFIDFKDRKIEIKRAEPR 321

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Yeast
Match: NSR1 (Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by polyphosphorylation [Source:SGD;Acc:S000003391])

HSP 1 Score: 53.5286 bits (127), Expect = 1.367e-7
Identity = 51/205 (24.88%), Postives = 90/205 (43.90%), Query Frame = 3

Query:  321 NKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFAD--YAAQVLCLAEKHLIDGRWC----AVKVPFSKNEADKQ------EISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIP------KPFRNFAFVTFDSSDTAQ----SLIGQSININGITLTIGSAVP 869
            NK++ +EE E+P              + V  L W +D+E L+K F   G ++  +V  +R T  S+GY ++ F +  YA + +   +   IDGR      +   P   N+  K+      E S  + +G  S     + +   F ++G V  + IP      +P + F +V F + + A+    +L G+ I+   + L   S  P
Sbjct:  156 NKKQKNEETEEPAT------------IFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQP-KGFGYVQFSNMEDAKKALDALQGEYIDNRPVRLDFSSPRP 347

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Yeast
Match: SNP1 (Component of U1 snRNP required for mRNA splicing via spliceosome; substrate of the arginine methyltransferase Hmt1p; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001323])

HSP 1 Score: 51.9878 bits (123), Expect = 3.172e-7
Identity = 28/77 (36.36%), Postives = 42/77 (54.55%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHL-----IDGRWCAVKV 614
            + +  L + +DE  L+KYF KFGE+  +++ KD+ T  SKGYAFI F D  +  +   E  +     I  R C V +
Sbjct:  109 IFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKEIGVHRGIQIKDRICIVDI 185

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO44940 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU25])

HSP 1 Score: 178.333 bits (451), Expect = 7.562e-50
Identity = 100/249 (40.16%), Postives = 142/249 (57.03%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVE-GWEDLKFYCVFPK---DNNKRKIDEEI--EKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPK 872
            D T+LL+ + G FP  CGL+YR PET  FR ++L +   Y P E GW D  F  V  K     +KRKI+E    ++P  K  ++EG    DLIVL L +   E  +++YF++FGE+   +VK D  T  S+G+ F+RF         L+  H I GR C V++P  K E +   + KK+ VG   E  + + L   F Q+G VTD++IPKPFR+F FVTF S + A+ ++ Q+  I+G  L I  A PK
Sbjct:   26 DGTLLLSNVNGQFPGACGLRYRNPETQAFRGVRLVEDVLYPPFEDGWGDTLFLVVPSKAADSASKRKIEESPIGKEPETKITKVEGVDVGDLIVLGLPYATTESEMKEYFTRFGEIDFCEVKLDPNTRRSRGFGFVRFKKDEDAKNVLSTSHRIQGRLCEVRLPRPKEELN---VPKKLFVGRLPESTTEKTLMEYFAQFGEVTDVYIPKPFRHFGFVTFASGELAKKVLSQNHRISGSLLNITFAEPK 271

HSP 2 Score: 56.225 bits (134), Expect = 2.828e-8
Identity = 29/77 (37.66%), Postives = 45/77 (58.44%), Query Frame = -2

Query: 3919 ITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKIT 4149
            + KK+ V    E    + L + F ++G V D++IPKPFR+F FVTF   E+A++++ +   + G  L I  A PK T
Sbjct:  197 VPKKLFVGRLPESTTEKTLMEYFAQFGEVTDVYIPKPFRHFGFVTFASGELAKKVLSQNHRISGSLLNITFAEPKST 273

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO36522 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF0])

HSP 1 Score: 78.1814 bits (191), Expect = 2.605e-16
Identity = 58/174 (33.33%), Postives = 83/174 (47.70%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEK-----HLIDGRWCAVK--VPFSKNEADKQEISKKIHVGYASEEISMEDLRIA----FEQYGYVTDIFIPKP----FRNFAFVTFDSSDTAQSLIG-QSININGITLTIGSAVPK 872
            L V  L  +   ETLR+YF  +GEL  V V  D  T  S+G+ ++ FADY      L +K     H IDG+   VK  +P   N A   E +KKI VG   E+ + ED++ A     E+     D+ + K      R FAFV  ++ D A  L   + I++ G  +    A P+
Sbjct:   16 LFVGGLNRETTNETLREYFEAYGELTDVVVICDSATKKSRGFGYVTFADYKVTRNVLKDKVENGAHRIDGKEVEVKRAIPRDDNSATSHEKTKKIFVGGLPEDATKEDIQEAIESLLEEKVDKVDLIMKKEDETKHRGFAFVELNNEDQADELCCVKKIHVKGKMVEAKKATPR 189

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO38417 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCX6])

HSP 1 Score: 76.2554 bits (186), Expect = 8.563e-15
Identity = 60/167 (35.93%), Postives = 86/167 (51.50%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFA--DYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAF-EQYGYVTDI-FIPKPF----RNFAFVTFDSSDTAQSLI-GQSININGITLTIGSAVPK 872
            L V  L ++  +E+L++YFSK+GELV V +K D  T   +G+AF++F     A  VL   + H++DGR    K P +          KKI VG    E S E +R  F + Y  V +I +I +      R F FV+FDS DT   +   Q  NI G  + +  A+PK
Sbjct:   31 LFVGGLSYETTKESLKEYFSKYGELVGVDIKMDALTGRPRGFAFVQFKHQSEADAVLNQVDPHVLDGRTIDPK-PAAPIGKPPHLRVKKIFVGGLKPETSDEKIREYFGKAYAPVKEIEYITEHSSNRRRGFCFVSFDSEDTVDKICETQFHNIEGNKVEVKRALPK 196

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO39879 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8S5])

HSP 1 Score: 73.1738 bits (178), Expect = 1.183e-14
Identity = 51/166 (30.72%), Postives = 80/166 (48.19%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFAD-YAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQ-EISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSLIGQSIN-INGITLTIGSAVPK 872
            + +  L W+   E LR++F KFGEL    V +D  T  S+G+ F+ F D  A  V+  +    +DG+    K+   K    K    +KKI +G  S   S ED++  F Q+G +T+  +      +  R F FVTF+S ++A        + IN   + +  A PK
Sbjct:    2 MFIGGLSWQTTAEGLRQHFEKFGELKECVVMRDPVTKRSRGFGFLTFKDPKAVDVVLNSGAQELDGKKIDPKLAVPKRAPAKMVTTTKKIFIGGLSTNTSEEDMKKYFSQFGKITETMLMFDKATQRHRGFGFVTFESENSADKACDTQYHLINNKKVEVKKAQPK 167

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Match: EDO40104 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S851])

HSP 1 Score: 55.4546 bits (132), Expect = 2.394e-9
Identity = 30/84 (35.71%), Postives = 49/84 (58.33%), Query Frame = 3

Query:  372 RLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADY-AAQVLCLAEKHLIDGRWCAVKVPF 620
            R +  K T L V  + ++  ++ LRK+F++FGE+    V KDR T  SKGY F+  A   AA++ C  ++ +I+GR   V + +
Sbjct:    3 RNQDTKFTKLFVGGIPYESGDDALRKFFAQFGEIREAVVIKDRVTKKSKGYGFVTMATSDAAELACKNKRPMIEGRQANVNLAY 86

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BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: tardbp (TAR DNA-binding protein 43-like [Source:NCBI gene;Acc:101167445])

HSP 1 Score: 239.965 bits (611), Expect = 2.660e-69
Identity = 116/249 (46.59%), Postives = 167/249 (67.07%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            D TVLL+T+   FP  CGL++R+P +   R ++L +G  + P  GW ++ +   +PKDN KRK+DE       K KR +  K +DLIVL L WK  E+ L+ YFS FGE+++VQVK+D +T +SKG+ F+RF +Y AQ   ++++H+IDGRWC  K+P SK   D+   S+K+ VG  +E+++ +DLR  F QYG VTD+FIPKPFR FAFVTF     AQSL G+ + I G+++ I +A PK + NR+
Sbjct:   24 DGTVLLSTVAAQFPGACGLRFRSPVSQCMRGVRLVEGVLHAPETGWGNVVYVVNYPKDN-KRKMDEIDASSAVKMKRGD-MKTSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKRDAKTGNSKGFGFVRFTEYEAQEKVISQRHMIDGRWCDCKLPNSKQGPDEPLRSRKVFVGRCTEDMTTDDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGVSVHISNAEPK-HGNRQ 269

HSP 2 Score: 81.2629 bits (199), Expect = 1.694e-15
Identity = 39/87 (44.83%), Postives = 57/87 (65.52%), Query Frame = -2

Query: 3886 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQF 4146
            ++K+ V    E++  +DLR+ F +YG V D+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK  GN++    A+F
Sbjct:  191 SRKVFVGRCTEDMTTDDLRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGVSVHISNAEPK-HGNRQYDRTARF 276

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: tardbpl (TAR DNA binding protein [Source:NCBI gene;Acc:101173545])

HSP 1 Score: 234.187 bits (596), Expect = 1.024e-68
Identity = 115/246 (46.75%), Postives = 163/246 (66.26%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINS 881
            D TVLL+++   FP  CGL+YR PE+   R ++L +G  + P   W +L +   +PKDN KRK++E       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVK+D +T +SKG+ F+RFADY  Q   + ++H+IDGRWC  K+P SK   D+   S+KI VG  +E+++ ++LR  F QYG VTD+FIPKPFR FAFVTF     AQ+L G+ + I G+++ I +A PK N+
Sbjct:   24 DGTVLLSSVAAQFPGACGLRYRNPESQCMRGVRLVEGVLHAPENEWGNLVYVVNYPKDN-KRKMEEIDAASAVKVKR-GFQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKRDAKTGNSKGFGFVRFADYETQTKVITQRHMIDGRWCDCKLPNSKVCPDEPMRSRKIFVGRCTEDMTPDELRQYFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQALCGEDLIIKGVSVHISNAEPKHNN 267

HSP 2 Score: 74.3294 bits (181), Expect = 1.007e-13
Identity = 35/74 (47.30%), Postives = 50/74 (67.57%), Query Frame = -2

Query: 3925 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPK 4146
            ++KI V    E++  ++LR+ F +YG V D+FIPKPFR FAFVTF   +VAQ L G  + +KG ++ I +A PK
Sbjct:  191 SRKIFVGRCTEDMTPDELRQYFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQALCGEDLIIKGVSVHISNAEPK 264

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: tardbpl (TAR DNA binding protein [Source:NCBI gene;Acc:101173545])

HSP 1 Score: 210.305 bits (534), Expect = 6.222e-61
Identity = 104/214 (48.60%), Postives = 144/214 (67.29%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTF 785
            D TVLL+++   FP  CGL+YR PE+   R ++L +G  + P   W +L +   +PKDN KRK++E       K KR   +K +DLIVL L WK  E+ L+ YFS FGE+++VQVK+D +T +SKG+ F+RFADY  Q   + ++H+IDGRWC  K+P SK   D+   S+KI VG  +E+++ ++LR  F QYG VTD+FIPKPFR FAFVTF
Sbjct:   24 DGTVLLSSVAAQFPGACGLRYRNPESQCMRGVRLVEGVLHAPENEWGNLVYVVNYPKDN-KRKMEEIDAASAVKVKR-GFQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVIMVQVKRDAKTGNSKGFGFVRFADYETQTKVITQRHMIDGRWCDCKLPNSKVCPDEPMRSRKIFVGRCTEDMTPDELRQYFMQYGEVTDVFIPKPFRAFAFVTF 235

HSP 2 Score: 56.225 bits (134), Expect = 7.496e-8
Identity = 24/45 (53.33%), Postives = 33/45 (73.33%), Query Frame = -2

Query: 4012 TKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTF 4146
            ++KI V    E++  ++LR+ F +YG V D+FIPKPFR FAFVTF
Sbjct:  191 SRKIFVGRCTEDMTPDELRQYFMQYGEVTDVFIPKPFRAFAFVTF 235

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: msi2a (musashi RNA binding protein 2 [Source:NCBI gene;Acc:101163923])

HSP 1 Score: 85.8853 bits (211), Expect = 1.417e-17
Identity = 49/145 (33.79%), Postives = 75/145 (51.72%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHL-IDGRWCAVKVPFSKNEADKQEI-SKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSL 812
            + +  L W+   ++LR YFSKFGE+    V +D  T  S+G+ F+ F D A+    LA++H  +D +    KV F +    K    +KKI VG  S    +ED++  FEQ+G V D  +         R F F+TF+S D  + +
Sbjct:   23 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFTDAASVDKVLAQQHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFITFESEDIVEKV 167

[Close]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Match: msi2a (musashi RNA binding protein 2 [Source:NCBI gene;Acc:101163923])

HSP 1 Score: 86.2705 bits (212), Expect = 1.738e-17
Identity = 49/145 (33.79%), Postives = 75/145 (51.72%), Query Frame = 3

Query:  399 LIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHL-IDGRWCAVKVPFSKNEADKQEI-SKKIHVGYASEEISMEDLRIAFEQYGYVTDIFI-----PKPFRNFAFVTFDSSDTAQSL 812
            + +  L W+   ++LR YFSKFGE+    V +D  T  S+G+ F+ F D A+    LA++H  +D +    KV F +    K    +KKI VG  S    +ED++  FEQ+G V D  +         R F F+TF+S D  + +
Sbjct:   23 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFTDAASVDKVLAQQHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFITFESEDIVEKV 167

[Close]

BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000032661.1 (SMESG000032661.1)

HSP 1 Score: 766.148 bits (1977), Expect = 0.000e+0
Identity = 448/448 (100.00%), Postives = 448/448 (100.00%), Query Frame = 3

Query:   81 MYYIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKXXXXXXXXXXXXXXHYPMYGDNMQSAQGYQTRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNXXXXXXXXXXXXXXXXXXXXMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQYGAGDPNQHGSXXXXXXXXXXXPEXXXXXXXXXXXXXXSNSMHSGGGGGKYNMK 1424
            MYYIAVCEYEESETIEIPVEEDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKGGAGGGGGSGGGGGHYPMYGDNMQSAQGYQTRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNAYAGATAAAAAAAAGYPGGGMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQYGAGDPNQHGSAANAALNILNNPEVVAAIVAAANKAGVSNSMHSGGGGGKYNMK
Sbjct:    1 MYYIAVCEYEESETIEIPVEEDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKGGAGGGGGSGGGGGHYPMYGDNMQSAQGYQTRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNAYAGATAAAAAAAAGYPGGGMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQYGAGDPNQHGSAANAALNILNNPEVVAAIVAAANKAGVSNSMHSGGGGGKYNMK 448

HSP 2 Score: 141.354 bits (355), Expect = 2.685e-35
Identity = 102/239 (42.68%), Postives = 127/239 (53.14%), Query Frame = -2

Query: 3547 QSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKK---------LPIPAQFPICPYNEQ---------GPMTAGRYG--W-SSYEPAPMQ-SSRYKARQFRNSAIMGNYGTLMSTAAVANSSSNQSY-LMSNGR------IHPHGLISFEYNHQQSSQQAVPAATDIGQN-TAAMAALNILNNPD 4173
            ++EADKQEI+KKIHV Y++EE+ MEDLR AFE+YGYV DIFIPKPFRNFAFVTF+ S+ AQ LIG+ + + G TLTIGSAVPKI  N+K               +P+   N Q          P     YG  W  SY+ A  Q ++R  +      A                 +   +Y LMSNG       +   G  S E  HQ    Q    A D  Q+ +AA AALNILNNP+
Sbjct:  182 KNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKGGAGGGGGSGGGGGHYPMYGDNMQSAQGYQTRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNAYAGATAAAAAAAAGYPGGGMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQY--GAGDPNQHGSAANAALNILNNPE 418

[Close]

BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000032661.1 (SMESG000032661.1)

HSP 1 Score: 710.679 bits (1833), Expect = 0.000e+0
Identity = 427/448 (95.31%), Postives = 428/448 (95.54%), Query Frame = 3

Query:   81 MYYIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKXXXXXXXXXXXXXXHYPMYGDNMQSAQGYQTRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNXXXXXXXXXXXXXXXXXXXXMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQYGAGDPNQHGSXXXXXXXXXXXPEXXXXXXXXXXXXXXSNSMHSGGGGGKYNMK 1424
            MYYIAVCEYEESETIEIPVEEDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQK                    +DEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKGGAGGGGGSGGGGGHYPMYGDNMQSAQGYQTRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNAYAGATAAAAAAAAGYPGGGMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQYGAGDPNQHGSAANAALNILNNPEVVAAIVAAANKAGVSNSMHSGGGGGKYNMK
Sbjct:    1 MYYIAVCEYEESETIEIPVEEDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQK--------------------IDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKGGAGGGGGSGGGGGHYPMYGDNMQSAQGYQTRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNAYAGATAAAAAAAAGYPGGGMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQYGAGDPNQHGSAANAALNILNNPEVVAAIVAAANKAGVSNSMHSGGGGGKYNMK 428

HSP 2 Score: 141.354 bits (355), Expect = 2.146e-35
Identity = 102/239 (42.68%), Postives = 127/239 (53.14%), Query Frame = -2

Query: 3547 QSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKK---------LPIPAQFPICPYNEQ---------GPMTAGRYG--W-SSYEPAPMQ-SSRYKARQFRNSAIMGNYGTLMSTAAVANSSSNQSY-LMSNGR------IHPHGLISFEYNHQQSSQQAVPAATDIGQN-TAAMAALNILNNPD 4173
            ++EADKQEI+KKIHV Y++EE+ MEDLR AFE+YGYV DIFIPKPFRNFAFVTF+ S+ AQ LIG+ + + G TLTIGSAVPKI  N+K               +P+   N Q          P     YG  W  SY+ A  Q ++R  +      A                 +   +Y LMSNG       +   G  S E  HQ    Q    A D  Q+ +AA AALNILNNP+
Sbjct:  162 KNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRKGGAGGGGGSGGGGGHYPMYGDNMQSAQGYQTRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNAYAGATAAAAAAAAGYPGGGMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQY--GAGDPNQHGSAANAALNILNNPE 398

[Close]

BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000032660.1 (SMESG000032660.1)

HSP 1 Score: 471.085 bits (1211), Expect = 2.747e-153
Identity = 245/246 (99.59%), Postives = 246/246 (100.00%), Query Frame = -2

Query: 3436 QSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQFPICPYNEQGPMTAGRYGWSSYEPAPMQSSRYKARQFRNSAIMGNYGTLMSTAAVANSSSNQSYLMSNGRIHPHGLISFEYNHQQSSQQAVPAATDIGQNTAAMAALNILNNPDXXXXXXXXXXXANKSGLSHHXXXXXQNLYSHQHGAMQ 4173
            +SEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQFPICPYNEQGPMTAGRYGWSSYEPAPMQSSRYKARQFRNSAIMGNYGTLMSTAAVANSSSNQSYLMSNGRIHPHGLISFEYNHQQSSQQAVPAATDIGQNTAAMAALNILNNPDVVAAIVAAAAAANKSGLSHHQQQQQQNLYSHQHGAMQ
Sbjct:  183 KSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKKLPIPAQFPICPYNEQGPMTAGRYGWSSYEPAPMQSSRYKARQFRNSAIMGNYGTLMSTAAVANSSSNQSYLMSNGRIHPHGLISFEYNHQQSSQQAVPAATDIGQNTAAMAALNILNNPDVVAAIVAAAAAANKSGLSHHQQQQQQNLYSHQHGAMQ 428

HSP 2 Score: 390.193 bits (1001), Expect = 4.401e-123
Identity = 182/250 (72.80%), Postives = 210/250 (84.00%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKD-NNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKINSNRK 890
            DDT+L TTL G FP V GLKYR   +  FRA+KLS+GK +KP+EGW  LK  CVFPK+ +NKRK  EE E P  K+KRL+ RKCTDLIVLNLGWKVDEE LR YFSKFG+LVLVQ+KKDRET+HSKGYAF+RFADY  QVLCLAE+HLIDGRWC+VKVPFSK+EADKQEI+KKIHV Y++EE+ MEDLR AFE+YGYV DIFIPKPFRNFAFVTF+ S+ AQ LIG+ + + G TLTIGSAVPKI  N+K
Sbjct:   22 DDTILFTTLSGQFPKVSGLKYRFSGSLNFRAIKLSEGKLFKPLEGWGSLKLICVFPKEIDNKRKCKEEYEIPTPKTKRLDTRKCTDLIVLNLGWKVDEEMLRNYFSKFGDLVLVQIKKDRETNHSKGYAFVRFADYDGQVLCLAEQHLIDGRWCSVKVPFSKSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNKK 271

[Close]

BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000032660.1 (SMESG000032660.1)

HSP 1 Score: 381.719 bits (979), Expect = 3.738e-122
Identity = 180/246 (73.17%), Postives = 207/246 (84.15%), Query Frame = 3

Query:  144 DDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKD-NNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININGITLTIGSAVPKIN 878
            DDT+L TTL G FP V GLKYR   +  FRA+KLS+GK +KP+EGW  LK  CVFPK+ +NKRK  EE E P  K+KRL+ RKCTDLIVLNLGWKVDEE LR YFSKFG+LVLVQ+KKDRET+HSKGYAF+RFADY  QVLCLAE+HLIDGRWC+VKVPFSK+EADKQEI+KKIHV Y++EE+ MEDLR AFE+YGYV DIFIPKPFRNFAFVTF+ S+ AQ LIG+ + + G TLTIGSAVPKI 
Sbjct:   22 DDTILFTTLSGQFPKVSGLKYRFSGSLNFRAIKLSEGKLFKPLEGWGSLKLICVFPKEIDNKRKCKEEYEIPTPKTKRLDTRKCTDLIVLNLGWKVDEEMLRNYFSKFGDLVLVQIKKDRETNHSKGYAFVRFADYDGQVLCLAEQHLIDGRWCSVKVPFSKSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKIT 267

HSP 2 Score: 178.333 bits (451), Expect = 1.295e-49
Identity = 85/86 (98.84%), Postives = 86/86 (100.00%), Query Frame = -2

Query: 3916 QSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITG 4173
            +SEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITG
Sbjct:  183 KSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITG 268

[Close]

BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Match: SMESG000012144.1 (SMESG000012144.1)

HSP 1 Score: 283.493 bits (724), Expect = 2.255e-84
Identity = 145/270 (53.70%), Postives = 195/270 (72.22%), Query Frame = 3

Query:   81 MYYIAVCXXXXXXXXXXXXXXDDTVLLTTLGGIFPNVCGLKYRAPETNTFRALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLEGRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAFIRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYASEEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSININ-GITLTIGSAVPKINSNR 887
            M Y+ VCE EE  TIE+P+EED T+LL+TL   FP   GLKY++ +T  +R ++ +  +FY P EGWE   + CV  KDN KRK D+E +  L K+K++EG+KCTDLIVLN+ W+ D+E L+ YFSKFG++V+VQVK++ +T  SKGYAFIRFADY AQV+CLAE+H ID RWC VK+P+SK   +  E+  KIHVG  SE ++ + LR  F QYG V  I+IP+PFR+FAFV+F+   TAQSL+G+ + IN    +TI +A PK N N+
Sbjct:    1 MKYVIVCEEEEEPTIELPLEEDGTLLLSTLTCQFPKATGLKYKSKDTGIYRGVRFASDRFYPPPEGWETYTYSCVLFKDN-KRKSDDE-QYTLAKTKKMEGKKCTDLIVLNIPWRTDDEALKMYFSKFGDVVMVQVKREPDTLKSKGYAFIRFADYDAQVMCLAEQHCIDNRWCEVKIPYSKMNPEANEVRNKIHVGRLSEAVTADVLRSFFNQYGKVESIYIPRPFRSFAFVSFEDESTAQSLLGRELKINDDCVVTISAASPKSNHNQ 268

HSP 2 Score: 87.0409 bits (214), Expect = 1.931e-17
Identity = 68/214 (31.78%), Postives = 98/214 (45.79%), Query Frame = -2

Query: 3550 MQSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVVDIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHT-LTIGSAVPKITGNKKLPIPAQFPICPYNEQGPMTAGRYGWSSYEPAPMQSSRYKARQFRNSAIMGNYGTLMSTAAVANSSSNQSYLMSNGRIHPHGLISF-EYNHQQSSQ---QAVPAATDIGQNTAAMAALNILNNP 4176
            M  EA+  E+  KIHV   +E +  + LR  F +YG V  I+IP+PFR+FAFV+FE    AQ L+GR + +     +TI +A PK   N+             N  G    G   W++Y+                  +  +         +  + S Q+ LM N    PH   ++ +  H  +SQ   Q      D+ QNT AMAALNI+NNP
Sbjct:  181 MNPEAN--EVRNKIHVGRLSEAVTADVLRSFFNQYGKVESIYIPRPFRSFAFVSFEDESTAQSLLGRELKINDDCVVTISAASPKSNHNQN------------NMNGRAQPGYGHWNTYD------------------VFSD-----GRGGMNRNRSCQNKLMPNSNQMPHEWSNYLQQQHMHASQAQAQRQFTTPDMSQNTNAMAALNIINNP 357

The following BLAST results are available for this feature:

BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
BLAST of TAR DNA-binding protein 43 vs. TrEMBL
BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
BLAST of TAR DNA-binding protein 43 vs. Ensembl Yeast
BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST

BLAST of TAR DNA-binding protein 43 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TARDBP	6.278e-73	48.59	TAR DNA binding protein [Source:HGNC Symbol;Acc:HG...	[more]
TARDBP	6.278e-73	48.59	TAR DNA binding protein [Source:HGNC Symbol;Acc:HG...	[more]
TARDBP	7.571e-73	48.59	TAR DNA binding protein [Source:HGNC Symbol;Acc:HG...	[more]
TARDBP	7.571e-73	48.59	TAR DNA binding protein [Source:HGNC Symbol;Acc:HG...	[more]
AL109811.3	7.571e-73	48.59	novel protein	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tdp-1	2.881e-36	30.50	Tar DNA-binding protein homolog 1 [Source:UniProt...	[more]
tdp-1	4.701e-36	31.23	Tar DNA-binding protein homolog 1 [Source:UniProt...	[more]
msi-1	4.699e-17	32.53	MuSashI (Fly neural) family; Neural RNA-binding pr...	[more]
sqd-1	3.638e-16	31.79	Homologous to Drosophila SQD (Squid) protein [Sou...	[more]
sqd-1	3.638e-16	31.79	Homologous to Drosophila SQD (Squid) protein [Sou...	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TBPH	5.843e-74	48.21	gene:FBgn0025790 transcript:FBtr0089626	[more]
TBPH	4.365e-73	48.02	gene:FBgn0025790 transcript:FBtr0089625	[more]
TBPH	4.365e-73	48.02	gene:FBgn0025790 transcript:FBtr0089624	[more]
TBPH	4.365e-73	48.02	gene:FBgn0025790 transcript:FBtr0089627	[more]
TBPH	4.365e-73	48.02	gene:FBgn0025790 transcript:FBtr0301643	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tardbp	1.748e-68	44.27	TAR DNA binding protein [Source:ZFIN;Acc:ZDB-GENE-...	[more]
tardbpl	2.678e-68	45.93	TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB...	[more]
tardbpl	2.678e-68	45.93	TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB...	[more]
tardbpl	2.678e-68	45.93	TAR DNA binding protein, like [Source:ZFIN;Acc:ZDB...	[more]
tardbp	1.410e-67	44.14	TAR DNA binding protein [Source:ZFIN;Acc:ZDB-GENE-...	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
jarid2	1.516e-73	49.26	jumonji and AT-rich interaction domain containing ...	[more]
jarid2	1.928e-46	50.00	jumonji and AT-rich interaction domain containing ...	[more]
kcnj4	2.074e-16	33.79	potassium inwardly rectifying channel subfamily J ...	[more]
kcnj4	2.569e-16	33.79	potassium inwardly rectifying channel subfamily J ...	[more]
kcnj4	2.781e-16	33.79	potassium inwardly rectifying channel subfamily J ...	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tardbp	7.918e-73	48.59	TAR DNA binding protein [Source:MGI Symbol;Acc:MGI...	[more]
Tardbp	1.184e-72	48.59	TAR DNA binding protein [Source:MGI Symbol;Acc:MGI...	[more]
Tardbp	1.184e-72	48.59	TAR DNA binding protein [Source:MGI Symbol;Acc:MGI...	[more]
Tardbp	1.184e-72	48.59	TAR DNA binding protein [Source:MGI Symbol;Acc:MGI...	[more]
Tardbp	1.184e-72	48.59	TAR DNA binding protein [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of TAR DNA-binding protein 43 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q28F51\|TADBP_XENTR	7.247e-73	49.26	TAR DNA-binding protein 43 OS=Xenopus tropicalis O...	[more]
sp\|Q5R5W2\|TADBP_PONAB	2.901e-72	48.59	TAR DNA-binding protein 43 OS=Pongo abelii OX=9601...	[more]
sp\|Q13148\|TADBP_HUMAN	3.015e-72	48.59	TAR DNA-binding protein 43 OS=Homo sapiens OX=9606...	[more]
sp\|Q921F2\|TADBP_MOUSE	1.292e-71	48.59	TAR DNA-binding protein 43 OS=Mus musculus OX=1009...	[more]
sp\|Q5ZLN5\|TADBP_CHICK	3.517e-71	48.19	TAR DNA-binding protein 43 OS=Gallus gallus OX=903...	[more]

BLAST of TAR DNA-binding protein 43 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4E0RSY0	3.090e-91	55.02	TAR DNA-binding protein 43 OS=Fasciola hepatica OX...	[more]
A0A504Z4S8	3.472e-91	56.65	TAR DNA-binding protein 43 OS=Fasciola gigantica O...	[more]
A0A2H1BSY3	6.321e-91	57.03	Uncharacterized protein OS=Fasciola hepatica OX=61...	[more]
A0A504YT28	5.612e-90	56.00	TAR DNA-binding protein 43 OS=Fasciola gigantica O...	[more]
A0A1S8WSG9	3.273e-89	51.75	Uncharacterized protein (Fragment) OS=Opisthorchis...	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tardbp	1.218e-69	46.03	TAR DNA-binding protein 43-like [Source:NCBI gene;...	[more]
tardbpl	5.150e-69	46.06	TAR DNA binding protein [Source:NCBI gene;Acc:1030...	[more]
tardbpl	1.103e-67	46.22	TAR DNA binding protein [Source:NCBI gene;Acc:1030...	[more]
msi2b	3.026e-18	33.78	RNA-binding protein Musashi homolog 2 [Source:NCBI...	[more]
msi2b	3.880e-18	33.78	RNA-binding protein Musashi homolog 2 [Source:NCBI...	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000009806.1	3.147e-63	44.05	pep scaffold:Pmarinus_7.0:GL479354:9188:12030:-1 g...	[more]
TARDBP	9.252e-54	49.21	TAR DNA binding protein [Source:HGNC Symbol;Acc:HG...	[more]
ENSPMAT00000007723.1	9.459e-27	45.63	pep scaffold:Pmarinus_7.0:GL496487:1152:2091:-1 ge...	[more]
ENSPMAT00000004893.1	1.364e-15	32.74	pep scaffold:Pmarinus_7.0:GL479484:4:2056:-1 gene:...	[more]
HNRNPA2B1	2.133e-11	29.94	heterogeneous nuclear ribonucleoprotein A2/B1 [Sou...	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
HRP1	8.360e-15	25.99	Subunit of cleavage factor I; cleavage factor I is...	[more]
NSR1	1.367e-7	24.88	Nucleolar protein that binds nuclear localization ...	[more]
SNP1	3.172e-7	36.36	Component of U1 snRNP required for mRNA splicing v...	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO44940	7.562e-50	40.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36522	2.605e-16	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38417	8.563e-15	35.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39879	1.183e-14	30.72	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40104	2.394e-9	35.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of TAR DNA-binding protein 43 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tardbp	2.660e-69	46.59	TAR DNA-binding protein 43-like [Source:NCBI gene;...	[more]
tardbpl	1.024e-68	46.75	TAR DNA binding protein [Source:NCBI gene;Acc:1011...	[more]
tardbpl	6.222e-61	48.60	TAR DNA binding protein [Source:NCBI gene;Acc:1011...	[more]
msi2a	1.417e-17	33.79	musashi RNA binding protein 2 [Source:NCBI gene;Ac...	[more]
msi2a	1.738e-17	33.79	musashi RNA binding protein 2 [Source:NCBI gene;Ac...	[more]

BLAST of TAR DNA-binding protein 43 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000032661.1	2.685e-35	100.00	SMESG000032661.1	[more]
SMESG000032661.1	2.146e-35	95.31	SMESG000032661.1	[more]
SMESG000032660.1	2.747e-153	99.59	SMESG000032660.1	[more]
SMESG000032660.1	3.738e-122	73.17	SMESG000032660.1	[more]
SMESG000012144.1	2.255e-84	53.70	SMESG000012144.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30015674 ID=SMED30015674|Name=TAR DNA-binding protein 43|organism=Schmidtea mediterranea sexual|type=transcript|length=4210bp
ATTGACTTGTCAAATATTTGATATTTTTGTTTTGAATTTTTATCTTTGAA
TTGAATATATTTCAATTTATTAATTAGTAAATGTATTATATTGCCGTATG
TGAGTATGAGGAATCAGAAACTATTGAAATTCCTGTAGAAGAAGATGACA
CGGTCTTATTAACTACTTTAGGTGGAATATTTCCCAATGTATGTGGACTG
AAATATCGAGCTCCCGAAACTAATACATTCAGGGCATTAAAATTAAGCGA
TGGCAAGTTTTACAAACCTGTTGAAGGATGGGAAGACCTTAAATTTTATT
GTGTATTTCCGAAAGATAACAATAAACGAAAAATTGACGAGGAGATAGAA
AAACCGTTACAGAAAAGTAAGAGATTAGAAGGTAGAAAATGCACAGATTT
GATCGTGTTAAACCTTGGTTGGAAAGTTGATGAAGAAACTTTACGAAAGT
ATTTCTCCAAATTTGGTGAACTTGTATTGGTGCAAGTAAAGAAAGACCGG
GAAACTAGCCACAGTAAAGGTTACGCATTTATTCGATTTGCCGATTACGC
CGCACAAGTGCTTTGCCTAGCTGAGAAGCATTTGATTGATGGCCGCTGGT
GTGCAGTTAAAGTTCCTTTTTCTAAGAACGAGGCTGACAAGCAGGAGATC
TCAAAGAAAATCCATGTCGGATACGCGTCGGAGGAGATCTCAATGGAGGA
TTTGCGCATCGCATTCGAGCAGTACGGATATGTCACCGATATTTTCATTC
CGAAACCTTTCCGTAATTTCGCATTCGTGACGTTTGACTCGAGTGACACG
GCGCAATCACTGATTGGACAGTCGATCAATATTAACGGTATCACGCTGAC
TATCGGGAGCGCGGTGCCCAAAATCAACAGCAACAGGAAAGGCGGAGCAG
GAGGAGGAGGCGGCAGTGGCGGCGGAGGGGGGCATTACCCCATGTATGGG
GACAACATGCAATCGGCACAAGGATATCAGACCAGGTACGCACCGGGAAT
GATACCGACATATGGCGCTGCTTGGCCACCCAGTTATGACATGGCAGCGG
CACAGAAGGCCGCCAGGATGAATTCCAGCAATGCTTATGCAGGGGCAACG
GCGGCAGCGGCTGCGGCTGCTGCTGGGTATCCGGGCGGCGGCATGCTCAC
TGGGCAAGCCGCATATCATCTCATGTCCAATGGCAACCGCGCCGGGCAAG
AGGCAATGCAGCAAGGCGGCTATGCCAGTCAGGAGATGATGCACCAGAAC
TACATGAGCCAATACGGTGCCGGGGATCCTAATCAGCACGGCAGCGCTGC
CAATGCCGCTCTCAACATCCTCAATAATCCAGAGGTGGTAGCTGCTATCG
TTGCGGCCGCAAACAAAGCCGGCGTCAGCAACTCGATGCATTCGGGTGGT
GGCGGTGGCAAGTACAACATGAAAAATGAGAGCTTCCAATGAGCAGGCAA
TTAGCTGCCGCCGGTTGGTCAAGTGGAGTGATCTGGTCTGGTGGTGCAGT
GCAGTGTGTAATGCTTGACTGTGTTGCTATGGGAATCGTTGTCAGTAGTC
GATGATCGATCGGGTTTATGTGAGTGCCGCAGCATTGTTGCTTGTGTAAT
AATTGTTGGTGTGCGCGCACACATTTGTTCTGAATGTAACTGCAATCGTG
CGCGTGTGTGTCGCCCTGTTGGTGTGTTCCTTCTGTGTTTGTGTGTCTGT
GTAAATATATGTAAATTGATTACACCAATAGTTTGATTTGCTGCTGTGAT
AAATTGTGTCGTGTTCACAGATTGTTTTGTGAGATTGGATTTATTTGTCA
ATATCGATTACTTCTTGCATTTGCTAATTAATAAATTAATTTCGTGAAAC
ATGAAGGCATTTTGATTGGTGGCCTCAATCAAGTAATTATTATTGATTTC
GGCGCTAATGCTCGGCACCTGACTACAACGGGCTGTCGTTGCCGGGTAAA
TGCGATTGATGATAGACTGATTGATGGGATCGTCGATTACTAACGGAGTT
GATGGGCTTGTCTTGACTGGTTATATGGACATTGAGGTATTGTCGGTATT
TAGTGAGGGATTGAGATATTAATTGGGGACCGTTCCACACCTTTGTGGTG
CATTTAGGTAACTGTCATGGCAAGGGATAAGGCAGGGCTGATAAAATTAG
CTAATCATGCCTATCAGGTTTATACAAAACTTTAAAGATTTTTTTTATTT
TGTTTTCGATAATAATAAATTGTTGGGATTGTGTAACTTGCTGTGAAACG
GAATATTTAGCAACTTGCATTGCAAGTGAAATGATAAATAGGATCAATTG
ATACGGTTATCTATAACTAGAGCAAATGATAATTCCTAATTTAGTGCAGA
ATTAAATGTAGAAATTTTTATTGATATCTATTTTATTACGATTTTCCTAC
TACCGGCTCCGATATTGCAGTGTAAGCGCCGCTTGCCAACGTTTTATTTG
CGTGAAATATTAAAACCGCACGATTTTTTTGTGTGCATGAAACGGATTAT
TAAATTCATATATGCACGAGTAAACTCGTAGTTGGCAGAGAATGGGGTAA
ATTTGTAACGGTTCAGCCGGCATCAATGGAAGCCCTCAATGGATATTCTC
AAATTCATGATTGTATTTATTTTATAAATTTTTATTAGGGCAATTGTGAC
CATATCTGATACATTTATAGCATAATCAGAATTCCAGCACGTTTCCTCGT
GATAATTGGGGTAACCTCAGAATTATTACCCAATTTGTGGATCATTCAAT
ATAAATATGAAATGCTCATAAAATCAAACTGAATTGACTTTAAAAATGGC
ATCGCATGAAATGTCGATTACTTTGCAGACATTCATAATAAAAAAGCTTT
TCTACAAGCCCAATCAACATCACACGTGTAAAATCGATAATGCAATGAAA
TGTTAAATATTATATTAAATTGCCAACTACATAATGATTCAAATGACAGA
ATGCGCACTGGGAACAATCAGCAATCATCAAGTGGAAACATATTTACAGC
CAATACAATGGACACCAAACCAGGAACGCAATTGGCACCGCATTTAGATC
ACTTGTAAAGCATCTCTAGCTCACCTCCAGACATCATTAACCAGCCAGAC
GACTAAAAATGGAAAATCACATCAAATTAATCAATAGAATTCACCATAAA
AAAGTTATTTTATCCAATCAAATAATGCCACAACAATCGATTCCAACACA
GGACAATGATAAAGGGCCGAGCAATTCATTGAAACGCCCCAATTTGCTGG
AGGAACCGCATCGATTTCCCCTGCAAAATCATATTACACAAGTGAGACAC
GCCAGTGACCAGATGACAACGCTATAAAGGTAGCGCAATTGGTAACAACC
CAAGGGTAGCCCTGTCCCCGGTACTCCTACAGCCCCCTCAAGCAACACAT
CATAATTGATTCGTCCCACACAAGGCACTCACCTACTGCATGGCACCGTG
CTGATGGCTGTATAAATTCTGCTGTTGCTGTTGCTGGTGGTGAGACAGAC
CGGATTTATTGGCAGCAGCCGCTGCCGCAACAATTGCCGCTACCACATCG
GGATTGTTGAGGATATTCAGTGCAGCCATGGCAGCAGTATTCTGTCCGAT
ATCTGTGGCAGCAGGGACGGCTTGCTGTGATGACTGCTGATGGTTGTACT
CGAATGAAATCAGGCCATGCGGATGGATTCGGCCGTTACTCATCAGATAC
GACTGATTGGATGAGGAGTTAGCAACGGCAGCAGTGGACATCAATGTCCC
GTAATTGCCCATAATTGCCGAGTTGCGGAATTGCCTGGCCTTGTACCGCG
ATGATTGCATCGGTGCCGGCTCGTAACTAGACCAGCCGTAGCGACCGGCT
GTCATTGGGCCCTGCTCATTATAAGGACAAATGGGAAATTGTGCTGGAAT
CGGTAATTTCTTGTTACCGGTAATTTTCGGCACAGCGCTGCCGATAGTGA
GCGTGTGGCCTTTCACCGTCACGCATCTGCCAATCAGCTGCTGGGCCACT
TCGCTCAATTCAAATGTTACGAAGGCGAAATTCCGGAACGGTTTCGGTAT
AAAAATGTCCACAACATAGCCATACTCCTCAAACGCTTTCCTCAGATCTT
CCATTTCCAGCTCCTCCGCACTGTAGCTAACGTGGATTTTCTTGGTAATT
TCCTGCTTGTCAGCCTCGCTCTGCATTAGAAACCGTAGGGTAACAATCGG
AGATCGGAAG

protein sequence of SMED30015674-orf-1

>SMED30015674-orf-1 ID=SMED30015674-orf-1|Name=SMED30015674-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=259bp
FRSPIVTLRFLMQSEADKQEITKKIHVSYSAEELEMEDLRKAFEEYGYVV
DIFIPKPFRNFAFVTFELSEVAQQLIGRCVTVKGHTLTIGSAVPKITGNK
KLPIPAQFPICPYNEQGPMTAGRYGWSSYEPAPMQSSRYKARQFRNSAIM
GNYGTLMSTAAVANSSSNQSYLMSNGRIHPHGLISFEYNHQQSSQQAVPA
ATDIGQNTAAMAALNILNNPDVVAAIVAAAAAANKSGLSHHQQQQQQNLY
SHQHGAMQ*

protein sequence of SMED30015674-orf-2

>SMED30015674-orf-2 ID=SMED30015674-orf-2|Name=SMED30015674-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=454bp
MYYIAVCEYEESETIEIPVEEDDTVLLTTLGGIFPNVCGLKYRAPETNTF
RALKLSDGKFYKPVEGWEDLKFYCVFPKDNNKRKIDEEIEKPLQKSKRLE
GRKCTDLIVLNLGWKVDEETLRKYFSKFGELVLVQVKKDRETSHSKGYAF
IRFADYAAQVLCLAEKHLIDGRWCAVKVPFSKNEADKQEISKKIHVGYAS
EEISMEDLRIAFEQYGYVTDIFIPKPFRNFAFVTFDSSDTAQSLIGQSIN
INGITLTIGSAVPKINSNRKGGAGGGGGSGGGGGHYPMYGDNMQSAQGYQ
TRYAPGMIPTYGAAWPPSYDMAAAQKAARMNSSNAYAGATAAAAAAAAGY
PGGGMLTGQAAYHLMSNGNRAGQEAMQQGGYASQEMMHQNYMSQYGAGDP
NQHGSAANAALNILNNPEVVAAIVAAANKAGVSNSMHSGGGGGKYNMKNE
SFQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0003676	nucleic acid binding
GO:0000166	nucleotide binding
GO:0003677	DNA binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0002089	reproductive organ
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR041105	TDP43_N
IPR035979	RBD_domain_sf
IPR000504	RRM_dom
IPR012677	Nucleotide-bd_a/b_plait_sf
IPR011528	NERD
IPR009465	Spondin_N

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000504	RNA recognition motif domain	SMART	SM00360	rrm1_1	coord: 193..259 e-value: 2.7E-6 score: 36.9 coord: 106..177 e-value: 1.1E-14 score: 64.8
IPR000504	RNA recognition motif domain	PFAM	PF00076	RRM_1	coord: 196..245 e-value: 4.5E-7 score: 29.6 coord: 107..163 e-value: 1.1E-11 score: 44.3
IPR000504	RNA recognition motif domain	PROSITE	PS50102	RRM	coord: 105..201 score: 13.771
IPR000504	RNA recognition motif domain	PROSITE	PS50102	RRM	coord: 192..270 score: 12.185
IPR041105	TAR DNA-binding protein 43, N-terminal	PFAM	PF18694	TDP43_N	coord: 3..76 e-value: 2.5E-26 score: 91.3
IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	GENE3D	G3DSA:3.30.70.330		coord: 188..270 e-value: 5.8E-16 score: 60.4
IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	GENE3D	G3DSA:3.30.70.330		coord: 93..187 e-value: 3.5E-20 score: 74.1
None	No IPR available	PANTHER	PTHR23147	SERINE/ARGININE RICH SPLICING FACTOR	coord: 2..393
None	No IPR available	PANTHER	PTHR23147:SF103	TAR DNA-BINDING PROTEIN 43	coord: 2..393
None	No IPR available	CDD	cd12321	RRM1_TDP43	coord: 106..182 e-value: 1.68166E-40 score: 137.518
IPR035979	RNA-binding domain superfamily	SUPERFAMILY	SSF54928	RNA-binding domain, RBD	coord: 107..246