low density lipoprotein receptor-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015642 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11Note: Hover over icons to view figure legend
Homology
BLAST of low density lipoprotein receptor-1 vs. Ensembl Human
Match: HSPG2 (heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273]) HSP 1 Score: 127.102 bits (318), Expect = 6.404e-29 Identity = 77/216 (35.65%), Postives = 97/216 (44.91%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSF 2564
C P C+NG C+ CD C D SDE +C P CE N + L W CDG+ DC + DE NC CG F C S N IP + CDE DC DE GC PQ+ + A++ Q VT TC A G P P++ WR NWG I + R + +L I+D K D G Y CEA+++R F
Sbjct: 285 CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDE-----LDCGP-PPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVT-----SEGGRGTLIIRDVKESDQGAYTCEAMNARGMVF 489 HSP 2 Score: 51.9878 bits (123), Expect = 7.008e-6 Identity = 91/401 (22.69%), Postives = 159/401 (39.65%), Query Frame = 3
Query: 642 LQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQS--VSYKIK---IITNP--ALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIG-------NDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVS--MLVISDISQINEGNYEC----RVGSSIKEVNLIVLLDEGLIETSPPILKVKE-------GQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQ--LMNDEIADQTSFIVLMKAEVSDSGYYIC--TEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSF 1751
L++ +V + G Y+C+ S + EA+ V + S SY+++ I +P + + G+ S +C + I W +++ + N + I + N GTY+CVAS + +S+ + + + + GP V+V G+ L C S+G A W + + L R G S +L IS + G Y C +G++ K+V +IV D G + P ++ +E G + C P+ + W+ +R+ +P WQ L D + ++ + DSG YIC T P G + I++ + T P V+AG+ V ++C A G P +F
Sbjct: 2976 LRLHLVSPADSGEYVCRAASGPGPE-QEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYG------VAQSVVNLSVHGPPTVSVLPE-GP-VWVKVGKAVTLEC---VSAGEPRSSARW----TRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIV--DTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAP---TIHWS------KLRSPLP---WQHRLEGDTL-------IIPRVAQQDSGQYICNATSPAGHAEAT--IILHVESPPYATTVPEHASVQAGETVQLQCL-------AHGTPPLTF 3330
BLAST of low density lipoprotein receptor-1 vs. Ensembl Human
Match: LRP4 (LDL receptor related protein 4 [Source:HGNC Symbol;Acc:HGNC:6696]) HSP 1 Score: 75.485 bits (184), Expect = 4.574e-13 Identity = 50/127 (39.37%), Postives = 64/127 (50.39%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH--WICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C P C NG+C+ + CD N C D SDE ++C P R+CE + P +N + I W CDG+ DCG+ DEQ CD + C K F CSD I + CD + DC G DE C S
Sbjct: 71 CSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDE-----QDCPP--RECEEDE--FPCQNGYCIRSLWHCDGDNDCGDNSDEQ-CD---MRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPS 184 HSP 2 Score: 55.0694 bits (131), Expect = 6.913e-7 Identity = 38/127 (29.92%), Postives = 53/127 (41.73%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C G C +G C+ CD C D+SDE T C +C + + W CDGE+DC + DE+NC+ C F C + + I + +C+ DC DE SPQ
Sbjct: 231 CRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVR-------LSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDE----SPQ 346 HSP 3 Score: 54.6842 bits (130), Expect = 9.456e-7 Identity = 45/159 (28.30%), Postives = 55/159 (34.59%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNC-----------------------------------------DGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
CQNG C+ + CD N C D SDE +CD RKC + HW CDG+ DC +G DE+NC D S C F C I G+ CD + DC DE CT+
Sbjct: 117 CQNGYCIRSLWHCDGDNDCGDNSDE------QCD--MRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTT 267
BLAST of low density lipoprotein receptor-1 vs. Ensembl Human
Match: LRP1 (LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692]) HSP 1 Score: 74.7146 bits (182), Expect = 7.837e-13 Identity = 42/126 (33.33%), Postives = 60/126 (47.62%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH---WICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C G C++G C+ N+ C++ C D SDE + +C R P + L + W+CDG DCG+ DE++C G C +F C + IP + CD+ DC GEDET C
Sbjct: 2605 CGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHC 2730 HSP 2 Score: 74.3294 bits (181), Expect = 9.521e-13 Identity = 48/129 (37.21%), Postives = 62/129 (48.06%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETG-CTSP 2300
C PG C N C++ CD N C D SDE P C + C KCE NN+ +P + W+CDG+ DCGN DE N S C F+C+ + IP + CD + DC DE+ C P
Sbjct: 854 CQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCE-NNRCIPNR------WLCDGDNDCGNSEDESNAT-CSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYP 974 HSP 3 Score: 71.2478 bits (173), Expect = 9.667e-12 Identity = 42/131 (32.06%), Postives = 65/131 (49.62%), Query Frame = 3
Query: 1902 KIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTCSDNKTIPRGYVCDENIDCSQGEDET 2285
+ + + C CQN C+ CD + C D SDE C + C P S C + +P++ W+CDG++DC +G DE G N+ C + F C + + IP+ +VCD + DC+ G DE+
Sbjct: 2727 ETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDE-AAHCEGKTCGPSSFSCPGTHVCVPER------WLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDES 2850 HSP 4 Score: 65.855 bits (159), Expect = 4.059e-10 Identity = 43/120 (35.83%), Postives = 60/120 (50.00%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C NGEC+ + CD + HC DKSDE P C R C R+C N + + + W C+G +DCG+G DE C+ + CG F C D I C++ +DC DE C++
Sbjct: 2532 CANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCS-NGRCVSN-----MLW-CNGADDCGDGSDEIPCNKTA---CGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSA 2641 HSP 5 Score: 64.6994 bits (156), Expect = 9.373e-10 Identity = 45/121 (37.19%), Postives = 58/121 (47.93%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDE 2282
C PG C G C A CD N C D SDE C P KC N+ +P + C+G+++CG+G DE++C + C F CS K IPR +VCD + DC G DE
Sbjct: 3374 CRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGI------FRCNGQDNCGDGEDERDCPEVT---CAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE 3485 HSP 6 Score: 64.3142 bits (155), Expect = 1.249e-9 Identity = 37/111 (33.33%), Postives = 54/111 (48.65%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDPITCRECDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETG 2288
C + CD N C D SDE R+C + R +C +N P + W CD E+DC +G DE +C+ F C F C +++ I + ++CD + DC G DE
Sbjct: 2666 CYAPSWVCDGANDCGDYSDE-----RDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKF----CSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAA 2767 HSP 7 Score: 64.3142 bits (155), Expect = 1.348e-9 Identity = 41/123 (33.33%), Postives = 51/123 (41.46%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C P C+N C+ CD N C D SDE+ T R C C I + W CDG+ DC +G DE++C C F C IP + CD + DC G DE C
Sbjct: 3536 CEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGR-------WKCDGDHDCADGSDEKDC----TPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC 3647 HSP 8 Score: 62.3882 bits (150), Expect = 5.125e-9 Identity = 40/122 (32.79%), Postives = 62/122 (50.82%), Query Frame = 3
Query: 1935 YRFCQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
+R +G C+ CD + C D SDE C R C+P +C+ NN+ +P + W CD + DCG+ DE++C + C F+C++ + I + CD + DC+ G DE CT
Sbjct: 3499 FRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCK-NNRCVPGR------WQCDYDNDCGDNSDEESC---TPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCT 3610 HSP 9 Score: 60.8474 bits (146), Expect = 1.343e-8 Identity = 40/117 (34.19%), Postives = 57/117 (48.72%), Query Frame = 3
Query: 1956 ECLENAKFCDKINHCADKSDEDPITCRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE--QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
C+ CD+ N C D SDE P C + C +C+ + + +P + W CDGE+DCG+G DE + CD C F C +N+ +P + CD + DC DE CT
Sbjct: 3465 RCIPRVWVCDRDNDCVDGSDE-PANCTQMTCGVDEFRCKDSGRCIPAR------WKCDGEDDCGDGSDEPKEECDE---RTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCT 3571 HSP 10 Score: 58.151 bits (139), Expect = 9.862e-8 Identity = 39/123 (31.71%), Postives = 59/123 (47.97%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCR--ECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDET 2285
CPP C +G C+ + CD + C D+SDE +C C P+++ N + + I+W CD + DCG+ DE C ++C F C+ + IP + CD + DC DET
Sbjct: 936 CPPNQFSCASGRCIPISWTCDLDDDCGDRSDES-ASCAYPTCFPLTQFTCNNGRCIN------INWRCDNDNDCGDNSDEAGCS----HSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDET 1047 HSP 11 Score: 57.3806 bits (137), Expect = 1.530e-7 Identity = 52/171 (30.41%), Postives = 76/171 (44.44%), Query Frame = 3
Query: 1788 KISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSD-NKTIPRGYVCDENIDCSQGEDETGC 2291
K++N G ++ L +PGG + + +GR S S C+N +C+ CD + C D SDE P C E C P +C P +ICDG+ DC + DE NCD ++ C F C++ N+ IP + C+ +C GEDE C
Sbjct: 3295 KVNNGGCSNLCLLSPGGGHKCACPTNFYLGSDGRTCVSNCTASQF------VCKNDKCIPFWWKCDTEDDCGDHSDEPP-DCPEFKCRPGQFQCSTGICTNPA-------FICDGDNDCQDNSDEANCD---IHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDC 3448 HSP 12 Score: 56.225 bits (134), Expect = 3.501e-7 Identity = 38/127 (29.92%), Postives = 56/127 (44.09%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRE--------CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDN-KTIPRGYVCDENIDCSQGEDETGCTS 2297
C +G C+ CD N C D SDE C C +C ++ +P + W CDG+ DC + DE++C+G + F C D+ + I + +VCD + DC DE C S
Sbjct: 1022 CNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIP------LRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCES 1142 HSP 13 Score: 56.225 bits (134), Expect = 3.531e-7 Identity = 35/113 (30.97%), Postives = 52/113 (46.02%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C NG C+ CD + CAD SDE ++C P +C+++ + + W CD + DC +G DE+ C G + C F C++ P + CD DC DE
Sbjct: 3582 CANGRCIAGRWKCDGDHDCADGSDE-----KDCTP---RCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC-GTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDE 3685 HSP 14 Score: 51.9878 bits (123), Expect = 7.199e-6 Identity = 39/123 (31.71%), Postives = 50/123 (40.65%), Query Frame = 3
Query: 1941 FCQNGECLENAKFCDKINHCADKSDEDPITCR--ECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQ----NCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
CQN +C+ CD CAD SDE P C C P +C N + L + W CDGE DC + DE +C F CS + + +C+ DC DE GC
Sbjct: 2824 MCQNRQCIPKHFVCDHDRDCADGSDESP-ECEYPTCGPSEFRC-ANGRCLSSR-----QWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGC 2939
BLAST of low density lipoprotein receptor-1 vs. Ensembl Human
Match: LRP4 (LDL receptor related protein 4 [Source:HGNC Symbol;Acc:HGNC:6696]) HSP 1 Score: 67.3958 bits (163), Expect = 1.073e-12 Identity = 50/131 (38.17%), Postives = 65/131 (49.62%), Query Frame = 3
Query: 1905 IYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH--WICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
+V C P C NG+C+ + CD N C D SDE ++C P R+CE + P +N + I W CDG+ DCG+ DEQ CD + C K F CSD I + CD + DC G DE C
Sbjct: 16 AHVLPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDE-----QDCPP--RECEEDE--FPCQNGYCIRSLWHCDGDNDCGDNSDEQ-CD---MRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENC 133
BLAST of low density lipoprotein receptor-1 vs. Ensembl Human
Match: VLDLR (very low density lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:12698]) HSP 1 Score: 73.1738 bits (178), Expect = 1.698e-12 Identity = 49/133 (36.84%), Postives = 62/133 (46.62%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINN-QILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
V C C NG+C+ + CD C D SDE P C R C C ++ Q +P + W CDGE DC +G DE+NC + C FTCS + I R +VC+ DCS G DE C P
Sbjct: 68 VKKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQCIP------VSWRCDGENDCDSGEDEENCGNIT---CSPDEFTCSSGRCISRNFVCNGQDDCSDGSDELDCAPP 191
BLAST of low density lipoprotein receptor-1 vs. Ensembl Celegans
Match: unc-52 (Basement membrane proteoglycan [Source:UniProtKB/Swiss-Prot;Acc:Q06561]) HSP 1 Score: 102.834 bits (255), Expect = 8.292e-22 Identity = 99/333 (29.73%), Postives = 148/333 (44.44%), Query Frame = 3
Query: 1641 LTITPREIRVRAGQRVDIECFSKNTQGRA--------SGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGG-LSLSDNNMDVF--------CSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDED--PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTR---FSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
+T+ P E VR G+ V EC ++ + G P S ++ GR I+ V +L+ G + +SD N + S ++VS+ + + C + C N EC++N CD C D+SDE P R C+P KC NN+ + K W+CDG++DCG+ DE NC+ S ++C F C D + +P + CD DC G DE GC P + T + + +LTC+A P P + WR NWG + R S + T LTI D + D G Y CEA++ + R +
Sbjct: 47 ITVFPSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPLPSSAHDS----GGRLTINPV-----QLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGLRQAGQCMADEKACGNNECVKNDYVCDGEPDCRDRSDEANCPAISRTCEPNEFKCN-NNKCVQKM------WLCDGDDDCGDNSDELNCNAKPSSSDCKPTEFQCHDRRQCVPSSFHCDGTNDCHDGSDEVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT--------LTIHDAQPVDQGAYTCEAINVKGRVLA 355
BLAST of low density lipoprotein receptor-1 vs. Ensembl Celegans
Match: unc-52 (Basement membrane proteoglycan [Source:UniProtKB/Swiss-Prot;Acc:Q06561]) HSP 1 Score: 100.138 bits (248), Expect = 4.566e-21 Identity = 100/334 (29.94%), Postives = 147/334 (44.01%), Query Frame = 3
Query: 1641 LTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG---------RDGRFKISNVGPAHKRLTAPGG-LSLSDNNMDVF--------CSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDED--PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTR---FSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
+T+ P E VR G+ V EC + R S N + +G GR I+ V +L+ G + +SD N + S ++VS+ + + C + C N EC++N CD C D+SDE P R C+P KC NN+ + K W+CDG++DCG+ DE NC+ S ++C F C D + +P + CD DC G DE GC P + T + + +LTC+A P P + WR NWG + R S + T LTI D + D G Y CEA++ + R +
Sbjct: 47 ITVFPSEKEVRDGRDVSFEC-----RARTSDNSVYPTVRWARVGGPLPSSAHDSGGRLTINPV-----QLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGLRQAGQCMADEKACGNNECVKNDYVCDGEPDCRDRSDEANCPAISRTCEPNEFKCN-NNKCVQKM------WLCDGDDDCGDNSDELNCNAKPSSSDCKPTEFQCHDRRQCVPSSFHCDGTNDCHDGSDEVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT--------LTIHDAQPVDQGAYTCEAINVKGRVLA 355
BLAST of low density lipoprotein receptor-1 vs. Ensembl Celegans
Match: unc-52 (Basement membrane proteoglycan [Source:UniProtKB/Swiss-Prot;Acc:Q06561]) HSP 1 Score: 100.138 bits (248), Expect = 4.636e-21 Identity = 100/334 (29.94%), Postives = 147/334 (44.01%), Query Frame = 3
Query: 1641 LTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG---------RDGRFKISNVGPAHKRLTAPGG-LSLSDNNMDVF--------CSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDED--PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTR---FSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
+T+ P E VR G+ V EC + R S N + +G GR I+ V +L+ G + +SD N + S ++VS+ + + C + C N EC++N CD C D+SDE P R C+P KC NN+ + K W+CDG++DCG+ DE NC+ S ++C F C D + +P + CD DC G DE GC P + T + + +LTC+A P P + WR NWG + R S + T LTI D + D G Y CEA++ + R +
Sbjct: 47 ITVFPSEKEVRDGRDVSFEC-----RARTSDNSVYPTVRWARVGGPLPSSAHDSGGRLTINPV-----QLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGLRQAGQCMADEKACGNNECVKNDYVCDGEPDCRDRSDEANCPAISRTCEPNEFKCN-NNKCVQKM------WLCDGDDDCGDNSDELNCNAKPSSSDCKPTEFQCHDRRQCVPSSFHCDGTNDCHDGSDEVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT--------LTIHDAQPVDQGAYTCEAINVKGRVLA 355
BLAST of low density lipoprotein receptor-1 vs. Ensembl Celegans
Match: unc-52 (Basement membrane proteoglycan [Source:UniProtKB/Swiss-Prot;Acc:Q06561]) HSP 1 Score: 100.138 bits (248), Expect = 5.055e-21 Identity = 100/334 (29.94%), Postives = 147/334 (44.01%), Query Frame = 3
Query: 1641 LTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG---------RDGRFKISNVGPAHKRLTAPGG-LSLSDNNMDVF--------CSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDED--PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTR---FSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
+T+ P E VR G+ V EC + R S N + +G GR I+ V +L+ G + +SD N + S ++VS+ + + C + C N EC++N CD C D+SDE P R C+P KC NN+ + K W+CDG++DCG+ DE NC+ S ++C F C D + +P + CD DC G DE GC P + T + + +LTC+A P P + WR NWG + R S + T LTI D + D G Y CEA++ + R +
Sbjct: 47 ITVFPSEKEVRDGRDVSFEC-----RARTSDNSVYPTVRWARVGGPLPSSAHDSGGRLTINPV-----QLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGLRQAGQCMADEKACGNNECVKNDYVCDGEPDCRDRSDEANCPAISRTCEPNEFKCN-NNKCVQKM------WLCDGDDDCGDNSDELNCNAKPSSSDCKPTEFQCHDRRQCVPSSFHCDGTNDCHDGSDEVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT--------LTIHDAQPVDQGAYTCEAINVKGRVLA 355
BLAST of low density lipoprotein receptor-1 vs. Ensembl Celegans
Match: unc-52 (Basement membrane proteoglycan [Source:UniProtKB/Swiss-Prot;Acc:Q06561]) HSP 1 Score: 100.138 bits (248), Expect = 5.173e-21 Identity = 100/334 (29.94%), Postives = 147/334 (44.01%), Query Frame = 3
Query: 1641 LTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG---------RDGRFKISNVGPAHKRLTAPGG-LSLSDNNMDVF--------CSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDED--PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTR---FSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
+T+ P E VR G+ V EC + R S N + +G GR I+ V +L+ G + +SD N + S ++VS+ + + C + C N EC++N CD C D+SDE P R C+P KC NN+ + K W+CDG++DCG+ DE NC+ S ++C F C D + +P + CD DC G DE GC P + T + + +LTC+A P P + WR NWG + R S + T LTI D + D G Y CEA++ + R +
Sbjct: 836 ITVFPSEKEVRDGRDVSFEC-----RARTSDNSVYPTVRWARVGGPLPSSAHDSGGRLTINPV-----QLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGLRQAGQCMADEKACGNNECVKNDYVCDGEPDCRDRSDEANCPAISRTCEPNEFKCN-NNKCVQKM------WLCDGDDDCGDNSDELNCNAKPSSSDCKPTEFQCHDRRQCVPSSFHCDGTNDCHDGSDEVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT--------LTIHDAQPVDQGAYTCEAINVKGRVLA 1144 HSP 2 Score: 61.6178 bits (148), Expect = 2.720e-9 Identity = 42/140 (30.00%), Postives = 62/140 (44.29%), Query Frame = 3
Query: 1767 IGRDGRFKISNVGPAHKRL------TAPGGLSLSDNNMDVFCSLEGRQVSSKIYV-SDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNC 2165
+ DGR + G H G + ++V E R S ++ SD CP G R C++G CL A+FCD+ C D DE+ + +C +CE N +P +CDG +DC +G DE+ C
Sbjct: 216 LAEDGRVTVYKKGDKHHLHIINATDADDGTYKMIVQGINVEADFEVRITSDRVATESDECPSGERACKSGHCLPVAQFCDRRVQCPDGDDEEHCSEVQCKSNEFRCESTNVCVPTV------VVCDGWKDCHDGSDEKKC 349
BLAST of low density lipoprotein receptor-1 vs. Ensembl Fly
Match: trol (gene:FBgn0284408 transcript:FBtr0342809) HSP 1 Score: 119.783 bits (299), Expect = 5.748e-27 Identity = 69/215 (32.09%), Postives = 100/215 (46.51%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVI 2585
C NGEC++ + CD C+D SDE + + KC+ N + W CDGE DCG+ DE +CD S C F C IP+ + CD DC+ G DE GC +P + V + +++ LTC ATG P P +VWR NWG + + + T +L D + D G Y+CE +++R F N ++
Sbjct: 753 CMNGECIDKSSICDGNPDCSDASDEQSCS------LGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKS-------YGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIV 954 HSP 2 Score: 62.7734 bits (151), Expect = 1.553e-9 Identity = 100/409 (24.45%), Postives = 160/409 (39.12%), Query Frame = 3
Query: 318 IRWLDKDGKVAAANRYLYIKSLL-----KQDEGIYNCSVEKVKDPQ----IRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT---------NILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNL----KQSVSYK--IKIITNPALFRYGERFSLRCEVEPF-YQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWY-INGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKE---VNLIVLLDEGLIETSPP--ILKVKEGQSVEFHCRVENIPSVKNVNLKW 1433
+ W DG A + Y L+ K DEG Y C E ++ I + ++ + + I PEE + G+ + C Q T V Y W + +++ ++ N L++ ES G Y C T + + + VN+ +Q K I+ + L GE +S+ CE Y +IK W K +F+ + L I + +N G Y CVA S DL SI R S +++ + P V G L+C +E G EW ++G+ PL R Q +VI DI + G+YECR + + E V I + + L++ P L++ EG + C +P N ++W
Sbjct: 2118 VTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNC------QFTSVASLRYDW-SHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIK--WAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGS---DLSSTSIDIEPRERPS-VKIVSAPLQTFSV--GAPASLYCTVE---GIPDPTVEWVRVDGQ-------PLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVP---NPEVEW 2498 HSP 3 Score: 53.9138 bits (128), Expect = 9.479e-7 Identity = 160/740 (21.62%), Postives = 269/740 (36.35%), Query Frame = 3
Query: 228 PLKNDSIVKSEMQFI--------NIACNVTNYALNETSIRWLDKDG----KVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIP---VVDESVV---GRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRY--GERFSLRCEVEPFYQNIKYTW-----YKKDEFIGNDQELVIKSFK--KDNVGTYKCVASLQLPSG----KLDLMEESIQQFAFFRESKIELTTKPGPQVY---VHR-----------GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECR-VG--SSIKE--VNLIVLLDEGLIETSPPI-LKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPRE--IRVRAGQRVDIECFSKNTQG-RASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSD------NNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCAD-KSDE---------DPITCRE------CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNC-----DGFSLNNCGGKFF 2204
P N I++S Q I +I C + SI+W V + L I ++ G+Y+C E + PS+ I P ++ +G C+ G+P D T W+ + + + +Q P V+D+ + G Y C+ K+ + EA + ++II + R G+ SL C V N + W K+D + ++K ++ K + G Y C + S ++++ E +S + PQ +H+ G+ L C++ R + ++G + NRL+ I + Q N G Y C +G ++K V +VL+ I P I L V+ GQ+++ HC+VEN V+ ++ W+ + NN P + + S + + + +G Y C+ N RS++ + K P+ R R G+ + ++C + G RA N EF++ RD R + N ++ L D N+ DV + +VS + V Y + G L++ C + CAD KS + P T R C P KC + + N +CDG DC + DE NC G S +N G F
Sbjct: 2279 PFGNKPIIESLEQNILIIQGEDYSITCEASGSPY--PSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIP------DPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNI----VGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTC-VGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWER----VDGAPLPRNAYTIKNRLE--------IVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVEN---VRPEDVHWSTD-------NNRP------LPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWF------RDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLRAPQYPYNRFKGGVSLKDTP-CMVLYICADFKSSKLSSAKPIISGPATTRAPAISYVCQPNDFKCVSHPHTCVRAN-----MVCDGIYDCTDHSDEFNCIAGKGSGKSESNSGSGSF 2965
BLAST of low density lipoprotein receptor-1 vs. Ensembl Fly
Match: trol (gene:FBgn0284408 transcript:FBtr0342811) HSP 1 Score: 119.783 bits (299), Expect = 6.060e-27 Identity = 69/215 (32.09%), Postives = 100/215 (46.51%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVI 2585
C NGEC++ + CD C+D SDE + + KC+ N + W CDGE DCG+ DE +CD S C F C IP+ + CD DC+ G DE GC +P + V + +++ LTC ATG P P +VWR NWG + + + T +L D + D G Y+CE +++R F N ++
Sbjct: 723 CMNGECIDKSSICDGNPDCSDASDEQSCS------LGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKS-------YGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIV 924 HSP 2 Score: 62.7734 bits (151), Expect = 1.549e-9 Identity = 100/409 (24.45%), Postives = 160/409 (39.12%), Query Frame = 3
Query: 318 IRWLDKDGKVAAANRYLYIKSLL-----KQDEGIYNCSVEKVKDPQ----IRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT---------NILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNL----KQSVSYK--IKIITNPALFRYGERFSLRCEVEPF-YQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWY-INGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKE---VNLIVLLDEGLIETSPP--ILKVKEGQSVEFHCRVENIPSVKNVNLKW 1433
+ W DG A + Y L+ K DEG Y C E ++ I + ++ + + I PEE + G+ + C Q T V Y W + +++ ++ N L++ ES G Y C T + + + VN+ +Q K I+ + L GE +S+ CE Y +IK W K +F+ + L I + +N G Y CVA S DL SI R S +++ + P V G L+C +E G EW ++G+ PL R Q +VI DI + G+YECR + + E V I + + L++ P L++ EG + C +P N ++W
Sbjct: 2088 VTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNC------QFTSVASLRYDW-SHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIK--WAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGS---DLSSTSIDIEPRERPS-VKIVSAPLQTFSV--GAPASLYCTVE---GIPDPTVEWVRVDGQ-------PLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVP---NPEVEW 2468 HSP 3 Score: 51.9878 bits (123), Expect = 3.329e-6 Identity = 120/572 (20.98%), Postives = 220/572 (38.46%), Query Frame = 3
Query: 72 YQTNKVSSMISICKIFALICIYQSLVKAETEEFT--FGGASEEEETSPPNITFFPLKNDSIVK---SEMQFINIACNVTNYA--LNETSIRWLDKDGKVAAANRY-----LYIKSLLKQDEGIYNCS-VEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKI--GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT-----NILQIPVVDESVVGRYIC----QYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFY-----QNIKYTWYKKDE------FIGNDQELVIKSFKKDNVGTYKCVA-----SLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVH-----RGEKKELHCEIETSSGN-RGKEA---EWYINGKKF------KNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLK--WNFESKEGLVRNNIPDSRWQLMNDEIADQTSF----IVLMKAEVSDSGYYICTE--PNGQTA 1598
Y+ K + I C ++ V+ E +E GG ++ + P N +N I + +++ +I NVT + RW DG N Y L I + +Q+ G Y C+ + + + + F + L + +P I P L + G + C + E + W N+ + ++ ++L+ + ++ G Y C QY ++ S+I A +K+ + + R GE L+C V Y N+++ W++ D + Q LV+ + + ++ G Y C + QLP +DL LT P P ++ + ++ +++ S N R E+ E Y + + ++ PL N + Q + LVIS++S + GNY C+ + DEG + T+ L+V++ + + S K V K N + + G + P RW ++ S + L + +D+G YICT +G+TA
Sbjct: 2491 YRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKEL---VLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDV------HWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNR--SQIARVA----VKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQV---------------LTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVR-QVGNRLVISNVSPSDAGNYVCKCKT-----------DEGDLYTTSYKLEVED--------QPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETA 3012
BLAST of low density lipoprotein receptor-1 vs. Ensembl Fly
Match: trol (gene:FBgn0284408 transcript:FBtr0342825) HSP 1 Score: 119.783 bits (299), Expect = 6.070e-27 Identity = 69/215 (32.09%), Postives = 100/215 (46.51%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVI 2585
C NGEC++ + CD C+D SDE + + KC+ N + W CDGE DCG+ DE +CD S C F C IP+ + CD DC+ G DE GC +P + V + +++ LTC ATG P P +VWR NWG + + + T +L D + D G Y+CE +++R F N ++
Sbjct: 984 CMNGECIDKSSICDGNPDCSDASDEQSCS------LGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKS-------YGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIV 1185 HSP 2 Score: 63.1586 bits (152), Expect = 1.314e-9 Identity = 100/409 (24.45%), Postives = 160/409 (39.12%), Query Frame = 3
Query: 318 IRWLDKDGKVAAANRYLYIKSLL-----KQDEGIYNCSVEKVKDPQ----IRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT---------NILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNL----KQSVSYK--IKIITNPALFRYGERFSLRCEVE-PFYQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWY-INGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKE---VNLIVLLDEGLIETSPP--ILKVKEGQSVEFHCRVENIPSVKNVNLKW 1433
+ W DG A + Y L+ K DEG Y C E ++ I + ++ + + I PEE + G+ + C Q T V Y W + +++ ++ N L++ ES G Y C T + + + VN+ +Q K I+ + L GE +S+ CE Y +IK W K +F+ + L I + +N G Y CVA S DL SI R S +++ + P V G L+C +E G EW ++G+ PL R Q +VI DI + G+YECR + + E V I + + L++ P L++ EG + C +P N ++W
Sbjct: 2349 VTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNC------QFTSVASLRYDW-SHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIK--WAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGS---DLSSTSIDIEPRERPS-VKIVSAPLQTFSV--GAPASLYCTVE---GIPDPTVEWVRVDGQ-------PLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVP---NPEVEW 2729 HSP 3 Score: 52.373 bits (124), Expect = 2.751e-6 Identity = 120/572 (20.98%), Postives = 220/572 (38.46%), Query Frame = 3
Query: 72 YQTNKVSSMISICKIFALICIYQSLVKAETEEFT--FGGASEEEETSPPNITFFPLKNDSIVK---SEMQFINIACNVTNYA--LNETSIRWLDKDGKVAAANRY-----LYIKSLLKQDEGIYNCS-VEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKI--GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT-----NILQIPVVDESVVGRYIC----QYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFY-----QNIKYTWYKKDE------FIGNDQELVIKSFKKDNVGTYKCVA-----SLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVH-----RGEKKELHCEIETSSGN-RGKEA---EWYINGKKF------KNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLK--WNFESKEGLVRNNIPDSRWQLMNDEIADQTSF----IVLMKAEVSDSGYYICTE--PNGQTA 1598
Y+ K + I C ++ V+ E +E GG ++ + P N +N I + +++ +I NVT + RW DG N Y L I + +Q+ G Y C+ + + + + F + L + +P I P L + G + C + E + W N+ + ++ ++L+ + ++ G Y C QY ++ S+I A +K+ + + R GE L+C V Y N+++ W++ D + Q LV+ + + ++ G Y C + QLP +DL LT P P ++ + ++ +++ S N R E+ E Y + + ++ PL N + Q + LVIS++S + GNY C+ + DEG + T+ L+V++ + + S K V K N + + G + P RW ++ S + L + +D+G YICT +G+TA
Sbjct: 2752 YRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKEL---VLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDV------HWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNR--SQIARVA----VKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQV---------------LTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVR-QVGNRLVISNVSPSDAGNYVCKCKT-----------DEGDLYTTSYKLEVED--------QPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETA 3273
BLAST of low density lipoprotein receptor-1 vs. Ensembl Fly
Match: trol (gene:FBgn0284408 transcript:FBtr0342821) HSP 1 Score: 119.783 bits (299), Expect = 6.224e-27 Identity = 69/215 (32.09%), Postives = 100/215 (46.51%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVI 2585
C NGEC++ + CD C+D SDE + + KC+ N + W CDGE DCG+ DE +CD S C F C IP+ + CD DC+ G DE GC +P + V + +++ LTC ATG P P +VWR NWG + + + T +L D + D G Y+CE +++R F N ++
Sbjct: 906 CMNGECIDKSSICDGNPDCSDASDEQSCS------LGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKS-------YGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIV 1107 HSP 2 Score: 63.1586 bits (152), Expect = 1.454e-9 Identity = 100/409 (24.45%), Postives = 160/409 (39.12%), Query Frame = 3
Query: 318 IRWLDKDGKVAAANRYLYIKSLL-----KQDEGIYNCSVEKVKDPQ----IRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT---------NILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNL----KQSVSYK--IKIITNPALFRYGERFSLRCEVEPF-YQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWY-INGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKE---VNLIVLLDEGLIETSPP--ILKVKEGQSVEFHCRVENIPSVKNVNLKW 1433
+ W DG A + Y L+ K DEG Y C E ++ I + ++ + + I PEE + G+ + C Q T V Y W + +++ ++ N L++ ES G Y C T + + + VN+ +Q K I+ + L GE +S+ CE Y +IK W K +F+ + L I + +N G Y CVA S DL SI R S +++ + P V G L+C +E G EW ++G+ PL R Q +VI DI + G+YECR + + E V I + + L++ P L++ EG + C +P N ++W
Sbjct: 2333 VTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNC------QFTSVASLRYDW-SHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIK--WAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGS---DLSSTSIDIEPRERPS-VKIVSAPLQTFSV--GAPASLYCTVE---GIPDPTVEWVRVDGQ-------PLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVP---NPEVEW 2713 HSP 3 Score: 51.9878 bits (123), Expect = 3.229e-6 Identity = 120/572 (20.98%), Postives = 220/572 (38.46%), Query Frame = 3
Query: 72 YQTNKVSSMISICKIFALICIYQSLVKAETEEFT--FGGASEEEETSPPNITFFPLKNDSIVK---SEMQFINIACNVTNYA--LNETSIRWLDKDGKVAAANRY-----LYIKSLLKQDEGIYNCS-VEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKI--GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT-----NILQIPVVDESVVGRYIC----QYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFY-----QNIKYTWYKKDE------FIGNDQELVIKSFKKDNVGTYKCVA-----SLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVH-----RGEKKELHCEIETSSGN-RGKEA---EWYINGKKF------KNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLK--WNFESKEGLVRNNIPDSRWQLMNDEIADQTSF----IVLMKAEVSDSGYYICTE--PNGQTA 1598
Y+ K + I C ++ V+ E +E GG ++ + P N +N I + +++ +I NVT + RW DG N Y L I + +Q+ G Y C+ + + + + F + L + +P I P L + G + C + E + W N+ + ++ ++L+ + ++ G Y C QY ++ S+I A +K+ + + R GE L+C V Y N+++ W++ D + Q LV+ + + ++ G Y C + QLP +DL LT P P ++ + ++ +++ S N R E+ E Y + + ++ PL N + Q + LVIS++S + GNY C+ + DEG + T+ L+V++ + + S K V K N + + G + P RW ++ S + L + +D+G YICT +G+TA
Sbjct: 2736 YRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKEL---VLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDV------HWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNR--SQIARVA----VKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQV---------------LTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVR-QVGNRLVISNVSPSDAGNYVCKCKT-----------DEGDLYTTSYKLEVED--------QPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETA 3257
BLAST of low density lipoprotein receptor-1 vs. Ensembl Fly
Match: trol (gene:FBgn0284408 transcript:FBtr0342824) HSP 1 Score: 119.783 bits (299), Expect = 6.297e-27 Identity = 69/215 (32.09%), Postives = 100/215 (46.51%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVI 2585
C NGEC++ + CD C+D SDE + + KC+ N + W CDGE DCG+ DE +CD S C F C IP+ + CD DC+ G DE GC +P + V + +++ LTC ATG P P +VWR NWG + + + T +L D + D G Y+CE +++R F N ++
Sbjct: 828 CMNGECIDKSSICDGNPDCSDASDEQSCS------LGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKS-------YGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIV 1029 HSP 2 Score: 63.1586 bits (152), Expect = 1.154e-9 Identity = 100/409 (24.45%), Postives = 160/409 (39.12%), Query Frame = 3
Query: 318 IRWLDKDGKVAAANRYLYIKSLL-----KQDEGIYNCSVEKVKDPQ----IRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT---------NILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNL----KQSVSYK--IKIITNPALFRYGERFSLRCEVEPF-YQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWY-INGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKE---VNLIVLLDEGLIETSPP--ILKVKEGQSVEFHCRVENIPSVKNVNLKW 1433
+ W DG A + Y L+ K DEG Y C E ++ I + ++ + + I PEE + G+ + C Q T V Y W + +++ ++ N L++ ES G Y C T + + + VN+ +Q K I+ + L GE +S+ CE Y +IK W K +F+ + L I + +N G Y CVA S DL SI R S +++ + P V G L+C +E G EW ++G+ PL R Q +VI DI + G+YECR + + E V I + + L++ P L++ EG + C +P N ++W
Sbjct: 2193 VTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNC------QFTSVASLRYDW-SHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIK--WAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGS---DLSSTSIDIEPRERPS-VKIVSAPLQTFSV--GAPASLYCTVE---GIPDPTVEWVRVDGQ-------PLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVP---NPEVEW 2573 HSP 3 Score: 52.373 bits (124), Expect = 2.185e-6 Identity = 121/579 (20.90%), Postives = 223/579 (38.51%), Query Frame = 3
Query: 72 YQTNKVSSMISICKIFALICIYQSLVKAETEEFT--FGGASEEEETSPPNITFFPLKNDSIVK---SEMQFINIACNVTNYA--LNETSIRWLDKDGKVAAANRY-----LYIKSLLKQDEGIYNCS-VEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKI--GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNT-----NILQIPVVDESVVGRYIC----QYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFY-----QNIKYTWYKKDE------FIGNDQELVIKSFKKDNVGTYKCVA-----SLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVH-----RGEKKELHCEIETSSGN-RGKEA---EWYINGKKF------KNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLK--WNFESKEGLVRNNIPDSRWQLMNDEIADQTSF----IVLMKAEVSDSGYYICTE--PNGQTARSELIVI 1619
Y+ K + I C ++ V+ E +E GG ++ + P N +N I + +++ +I NVT + RW DG N Y L I + +Q+ G Y C+ + + + + F + L + +P I P L + G + C + E + W N+ + ++ ++L+ + ++ G Y C QY ++ S+I A +K+ + + R GE L+C V Y N+++ W++ D + Q LV+ + + ++ G Y C + QLP +DL LT P P ++ + ++ +++ S N R E+ E Y + + ++ PL N + Q + LVIS++S + GNY C+ + DEG + T+ L+V++ + + S K V K N + + G + P RW ++ S + L + +D+G YICT +G+TA I++
Sbjct: 2596 YRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKEL---VLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDV------HWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNR--SQIARVA----VKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQV---------------LTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVR-QVGNRLVISNVSPSDAGNYVCKCKT-----------DEGDLYTTSYKLEVED--------QPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILV 3124
BLAST of low density lipoprotein receptor-1 vs. Ensembl Zebrafish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 126.716 bits (317), Expect = 6.424e-29 Identity = 78/211 (36.97%), Postives = 105/211 (49.76%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPI-TCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
CQNG+C+ CD + C D SDE T C+P KC+ L W CDG+ DC + DE NC C + F C SD K IP Y CDE DC+ DE GC P +T + + A++ VT TC A G P+P++ WR NWG I + R + S + +LTI+D K GD G Y CEA++++ F+
Sbjct: 206 CQNGQCISREYLCDGESDCTDGSDESRCGTPSPCEPNEFKCQ-------NGRCALKLWRCDGDNDCQDNSDEMNCPTKRPGAACAPEQFVCLSDRKCIPASYQCDEEPDCADRSDEFGCAPPTVTVSPEESITASRGDTVTFTCSAIGVPVPIITWRLNWGHIPANNRIT--MISENGQ---GTLTIRDVKEGDQGAYTCEAINAKGLVFA 404 HSP 2 Score: 82.0333 bits (201), Expect = 3.023e-15 Identity = 129/536 (24.07%), Postives = 202/536 (37.69%), Query Frame = 3
Query: 270 INIACNVTNYALNETSIRW--LDKDGKVAAANRYLYIKSLLKQ-------DEGIYNCSVEKVKDP-QIRFNRTLHLKITIPSISIDILPEESLKI--GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKD-------EFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLD-LMEESIQQFAFFRE-------SKIELTTKPGPQVYVHRGEKKELHCEIE-TSSGNRGKEAEWYINGKKFKNGDIPLVNRL-DGQYVSMLVISDISQINEGNYECRVGSSIKEVN-----LIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQT----SFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNK 1763
IN+ C S+RW LD + K ++ S + Q D G Y CS + + + R + +P++ + E + + G C G P+ TI + L ++K + N+ IL P V G+Y+C T+ + + + L+ + N R GE L+C + ++Y W K + + G D L I K+++ GTY+CVAS ++ GK + L + S++ F F S L+ K PQV E K L +E T + G + EW G G +P + + DG +L I ++ Q NEG Y CRV S + LI L + I + V G SVEF C P P RW + + D + + + + SDSG Y CT N + +V+ + + P V G + C ASG P + T +K
Sbjct: 2166 INLECQAAGEP--RPSVRWHRLDNNRKTMLSSTVPVDSSAIIQVLVARPEDSGTYVCSAQNNQGTTETRVEVFVEGGPQVPTVPRASVREPMIIVVEGSTATLHCDAHGFPKPTITWFKERSSLPWRHKIVDNSLIL--PNVGRQDSGQYVC----NATNHLGTSEVTIMLEVDTPPYATSLPNDVSVRVGEVIRLQC-LAHGTPPLRYEWTKINGSLPSTAQLQGGD--LQINLAKENDAGTYRCVASNKV--GKSEALAKVSVRYFFTFPHLELCPVFSAASLSVKVSPQV-----EVKALGSAVEFTCAAKGGLQIEWLKEG-----GVLPPNHHIKDG----ILRIENLEQSNEGIYTCRVTSQFEHAQDSAKLLIQALPKVKINVRTSVQTVMVGNSVEFECHAIGDPE---------------------PTVRWSKVGAPLPDHVEIRGNILRIDQVFESDSGQYRCTATNDVGSEHSHVVLNIQSLPQIAALPESKEVTIGSDAVLPCI-------ASGYPVPTITWSK 2646 HSP 3 Score: 71.633 bits (174), Expect = 3.839e-12 Identity = 84/339 (24.78%), Postives = 138/339 (40.71%), Query Frame = 3
Query: 768 IKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEF-------IGNDQELV-IKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYI---NGKKFKNGDIP---------LVNRLD--GQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNS-LTITPREIRVRAGQRVDIECFSKNT 1715
I I + A+ + GE S RC+V Q ++ W + +G D ++ + + + N GTY+CVAS L M SI RES + T GP V V G+ L C+ ++G W+ N K + +P LV R + G YV +Q N+G E RV ++ + + + P++ V EG + HC P + W E R+++P W+ +I D + ++L DSG Y+C N SE+ ++ + D T P ++ VR G+ + ++C + T
Sbjct: 2059 ISIEPHSAVVKQGESASFRCKVHNGAQPVRLEWKLTNNLPLPDNVKVGPDSSIMTVTNAQAKNQGTYRCVAS------NLYGMTHSIVSL-IVRESPKAVVTPAGP-VRVRVGDPINLECQ---AAGEPRPSVRWHRLDNNRKTMLSSTVPVDSSAIIQVLVARPEDSGTYVCS------AQNNQGTTETRVEVFVEGGPQVPTVPRASVRE--PMIIVVEGSTATLHCDAHGFP---KPTITWFKE------RSSLP---WR---HKIVDNS--LILPNVGRQDSGQYVCNATN-HLGTSEVTIMLEVDTPPYATSLPNDVSVRVGEVIRLQCLAHGT 2360 HSP 4 Score: 71.2478 bits (173), Expect = 5.386e-12 Identity = 120/560 (21.43%), Postives = 209/560 (37.32%), Query Frame = 3
Query: 216 ITFFPLKNDSIVKSEMQF-INIACNVTNYALNETSIRWLDKDGK--VAAANRY-----LYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLH--LKITIPSISIDILPEE----SLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGN-----TNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVE----PFYQNIKYTWYK-KDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHR-----GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYEC----RVGSSIKEVNLIVLLDEGLIE---TSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNS------LTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPI 1769
ITF + D + E N C V+ + +W +DG+ ++A R L+ + D G+Y C+ Q NR+ + T+PS I++ EE S+++G + C+ ++ + +T W + N + N IL I V G Y+C + A YV + V + + G+ RC V P + I + + + + + +L I S + + G Y C A L+ E + +S + P QV R GE L+C + G+ +W R+D + LV+ +I + G Y C GSS +++ V E ++ PP V EG++++ +C V P ++KW+ GL+ +N Q++ + +++A D+G YICT NG + + + + S ++I P V+ G+ C N G E+ TNN P+
Sbjct: 1594 ITFIQILEDFAIPPEFNAKSNKMCQVSGSPPH--YFQWSREDGRPISSSAERRRQGEELHFPGIQSNDAGVYICTCRD----QRSSNRSKAEIVVATLPSKPIEVFIEEPKAQSVRVGSTVSFICT-----AKSKLPAYTLVWTRKGNGKLPNRAMDFNGILTIQNVQPEDAGIYVCTGSNMLGMDEGSAVLYVPAAEGVQPVATLSPPVQTVKEGDVAQFRCTVTGNPTPAVEWIGGSGKRISSKAVIRNGQLTISSVDRSDEGEYICKA--------LNTHGEHTARGVLHVQSTGQPNGLPHVQVSPQRVEIYEGETLRLYCR---AIGSPTPSLKWN-------------KARMDRTDIGTLVVPNIRLSDAGTYLCVGTNAAGSSEAHIDVSVTKGENILSGVIIQPPSASVIEGEALDLNCLV---PGTSTGSVKWSRAG--GLLSSN-----HQVLETRLR-------ILRASADDTGDYICTVENGPSPQKATVSVSVTSSASRLQTPIISIEPHSAVVKQGESASFRCKVHN--GAQPVRLEWKLTNNLPL 2099
BLAST of low density lipoprotein receptor-1 vs. Ensembl Zebrafish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 126.331 bits (316), Expect = 6.606e-29 Identity = 78/211 (36.97%), Postives = 105/211 (49.76%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPI-TCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
CQNG+C+ CD + C D SDE T C+P KC+ L W CDG+ DC + DE NC C + F C SD K IP Y CDE DC+ DE GC P +T + + A++ VT TC A G P+P++ WR NWG I + R + S + +LTI+D K GD G Y CEA++++ F+
Sbjct: 271 CQNGQCISREYLCDGESDCTDGSDESRCGTPSPCEPNEFKCQ-------NGRCALKLWRCDGDNDCQDNSDEMNCPTKRPGAACAPEQFVCLSDRKCIPASYQCDEEPDCADRSDEFGCAPPTVTVSPEESITASRGDTVTFTCSAIGVPVPIITWRLNWGHIPANNRIT--MISENGQ---GTLTIRDVKEGDQGAYTCEAINAKGLVFA 469 HSP 2 Score: 78.1814 bits (191), Expect = 4.749e-14 Identity = 125/528 (23.67%), Postives = 199/528 (37.69%), Query Frame = 3
Query: 270 INIACNVTNYALNETSIRW--LDKDGKVAAANRYLYIKSLLKQ-------DEGIYNCSVEKVKDP-QIRFNRTLHLKITIPSISIDILPEESLKI--GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKD-------EFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIE-TSSGNRGKEAEWYINGKKFKNGDIPLVNRL-DGQYVSMLVISDISQINEGNYECRVGSSIKEVN-----LIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQT----SFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNK 1763
IN+ C S+RW LD + K ++ S + Q D G Y CS + + + R + +P++ + E + + G C G P+ TI + L ++K + N+ IL P V G+Y+C T+ + + + L+ + N R GE L+C + ++Y W K + + G D L I K+++ GTY+CVAS ++ GK E++ + + + L+ K PQV E K L +E T + G + EW G G +P + + DG +L I ++ Q NEG Y CRV S + LI L + I + V G SVEF C P P RW + + D + + + + SDSG Y CT N + +V+ + + P V G + C ASG P + T +K
Sbjct: 2225 INLECQAAGEP--RPSVRWHRLDNNRKTMLSSTVPVDSSAIIQVLVARPEDSGTYVCSAQNNQGTTETRVEVFVEGGPQVPTVPRASVREPMIIVVEGSTATLHCDAHGFPKPTITWFKERSSLPWRHKIVDNSLIL--PNVGRQDSGQYVC----NATNHLGTSEVTIMLEVDTPPYATSLPNDVSVRVGEVIRLQC-LAHGTPPLRYEWTKINGSLPSTAQLQGGD--LQINLAKENDAGTYRCVASNKV--GK----SEALAKVSV----RSSLSVKVSPQV-----EVKALGSAVEFTCAAKGGLQIEWLKEG-----GVLPPNHHIKDG----ILRIENLEQSNEGIYTCRVTSQFEHAQDSAKLLIQALPKVKINVRTSVQTVMVGNSVEFECHAIGDPE---------------------PTVRWSKVGAPLPDHVEIRGNILRIDQVFESDSGQYRCTATNDVGSEHSHVVLNIQSLPQIAALPESKEVTIGSDAVLPCI-------ASGYPVPTITWSK 2689 HSP 3 Score: 72.4034 bits (176), Expect = 2.393e-12 Identity = 112/525 (21.33%), Postives = 198/525 (37.71%), Query Frame = 3
Query: 318 IRWLDKDGK--VAAANRY-----LYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLH--LKITIPSISIDILPEE----SLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGN-----TNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVE----PFYQNIKYTWYK-KDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHR-----GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYEC----RVGSSIKEVNLIVLLDEGLIE---TSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNS------LTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPI 1769
+W +DG+ ++A R L+ + D G+Y C+ Q NR+ + T+PS I++ EE S+++G + C+ ++ + +T W + N + N IL I V G Y+C + A YV + V + + G+ RC V P + I + + + + + +L I S + + G Y C A L+ E + +S + P QV R GE L+C + G+ +W N++D + LV+ +I + G Y C GSS +++ V E ++ PP V EG++++ +C V P ++KW+ GL+ +N Q++ + +++A D+G YICT NG + + + + S ++I P V+ G+ C N G E+ TNN P+
Sbjct: 1688 FQWSREDGRPISSSAERRRQGEELHFPGIQSNDAGVYICTCRD----QRSSNRSKAEIVVATLPSKPIEVFIEEPKAQSVRVGSTVSFICT-----AKSKLPAYTLVWTRKGNGKLPNRAMDFNGILTIQNVQPEDAGIYVCTGSNMLGMDEGSAVLYVPAAEGVQPVATLSPPVQTVKEGDVAQFRCTVTGNPTPAVEWIGGSGKRISSKAVIRNGQLTISSVDRSDEGEYICKA--------LNTHGEHTARGVLHVQSTGQPNGLPHVQVSPQRVEIYEGETLRLYCR---AIGSPTPSLKW---------------NKMDRTDIGTLVVPNIRLSDAGTYLCVGTNAAGSSEAHIDVSVTKGENILSGVIIQPPSASVIEGEALDLNCLV---PGTSTGSVKWSRAG--GLLSSN-----HQVLETRLR-------ILRASADDTGDYICTVENGPSPQKATVSVSVTSSASRLQTPIISIEPHSAVVKQGESASFRCKVHN--GAQPVRLEWKLTNNLPL 2158 HSP 4 Score: 71.633 bits (174), Expect = 3.876e-12 Identity = 84/339 (24.78%), Postives = 138/339 (40.71%), Query Frame = 3
Query: 768 IKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEF-------IGNDQELV-IKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYI---NGKKFKNGDIP---------LVNRLD--GQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNS-LTITPREIRVRAGQRVDIECFSKNT 1715
I I + A+ + GE S RC+V Q ++ W + +G D ++ + + + N GTY+CVAS L M SI RES + T GP V V G+ L C+ ++G W+ N K + +P LV R + G YV +Q N+G E RV ++ + + + P++ V EG + HC P + W E R+++P W+ +I D + ++L DSG Y+C N SE+ ++ + D T P ++ VR G+ + ++C + T
Sbjct: 2118 ISIEPHSAVVKQGESASFRCKVHNGAQPVRLEWKLTNNLPLPDNVKVGPDSSIMTVTNAQAKNQGTYRCVAS------NLYGMTHSIVSL-IVRESPKAVVTPAGP-VRVRVGDPINLECQ---AAGEPRPSVRWHRLDNNRKTMLSSTVPVDSSAIIQVLVARPEDSGTYVCS------AQNNQGTTETRVEVFVEGGPQVPTVPRASVRE--PMIIVVEGSTATLHCDAHGFP---KPTITWFKE------RSSLP---WR---HKIVDNS--LILPNVGRQDSGQYVCNATN-HLGTSEVTIMLEVDTPPYATSLPNDVSVRVGEVIRLQCLAHGT 2419
BLAST of low density lipoprotein receptor-1 vs. Ensembl Zebrafish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 126.331 bits (316), Expect = 6.929e-29 Identity = 78/211 (36.97%), Postives = 105/211 (49.76%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPI-TCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
CQNG+C+ CD + C D SDE T C+P KC+ L W CDG+ DC + DE NC C + F C SD K IP Y CDE DC+ DE GC P +T + + A++ VT TC A G P+P++ WR NWG I + R + S + +LTI+D K GD G Y CEA++++ F+
Sbjct: 206 CQNGQCISREYLCDGESDCTDGSDESRCGTPSPCEPNEFKCQ-------NGRCALKLWRCDGDNDCQDNSDEMNCPTKRPGAACAPEQFVCLSDRKCIPASYQCDEEPDCADRSDEFGCAPPTVTVSPEESITASRGDTVTFTCSAIGVPVPIITWRLNWGHIPANNRIT--MISENGQ---GTLTIRDVKEGDQGAYTCEAINAKGLVFA 404 HSP 2 Score: 78.1814 bits (191), Expect = 4.780e-14 Identity = 125/528 (23.67%), Postives = 199/528 (37.69%), Query Frame = 3
Query: 270 INIACNVTNYALNETSIRW--LDKDGKVAAANRYLYIKSLLKQ-------DEGIYNCSVEKVKDP-QIRFNRTLHLKITIPSISIDILPEESLKI--GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKD-------EFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIE-TSSGNRGKEAEWYINGKKFKNGDIPLVNRL-DGQYVSMLVISDISQINEGNYECRVGSSIKEVN-----LIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQT----SFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNK 1763
IN+ C S+RW LD + K ++ S + Q D G Y CS + + + R + +P++ + E + + G C G P+ TI + L ++K + N+ IL P V G+Y+C T+ + + + L+ + N R GE L+C + ++Y W K + + G D L I K+++ GTY+CVAS ++ GK E++ + + + L+ K PQV E K L +E T + G + EW G G +P + + DG +L I ++ Q NEG Y CRV S + LI L + I + V G SVEF C P P RW + + D + + + + SDSG Y CT N + +V+ + + P V G + C ASG P + T +K
Sbjct: 2160 INLECQAAGEP--RPSVRWHRLDNNRKTMLSSTVPVDSSAIIQVLVARPEDSGTYVCSAQNNQGTTETRVEVFVEGGPQVPTVPRASVREPMIIVVEGSTATLHCDAHGFPKPTITWFKERSSLPWRHKIVDNSLIL--PNVGRQDSGQYVC----NATNHLGTSEVTIMLEVDTPPYATSLPNDVSVRVGEVIRLQC-LAHGTPPLRYEWTKINGSLPSTAQLQGGD--LQINLAKENDAGTYRCVASNKV--GK----SEALAKVSV----RSSLSVKVSPQV-----EVKALGSAVEFTCAAKGGLQIEWLKEG-----GVLPPNHHIKDG----ILRIENLEQSNEGIYTCRVTSQFEHAQDSAKLLIQALPKVKINVRTSVQTVMVGNSVEFECHAIGDPE---------------------PTVRWSKVGAPLPDHVEIRGNILRIDQVFESDSGQYRCTATNDVGSEHSHVVLNIQSLPQIAALPESKEVTIGSDAVLPCI-------ASGYPVPTITWSK 2624 HSP 3 Score: 72.4034 bits (176), Expect = 2.781e-12 Identity = 112/525 (21.33%), Postives = 198/525 (37.71%), Query Frame = 3
Query: 318 IRWLDKDGK--VAAANRY-----LYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLH--LKITIPSISIDILPEE----SLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGN-----TNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVE----PFYQNIKYTWYK-KDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHR-----GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYEC----RVGSSIKEVNLIVLLDEGLIE---TSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNS------LTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPI 1769
+W +DG+ ++A R L+ + D G+Y C+ Q NR+ + T+PS I++ EE S+++G + C+ ++ + +T W + N + N IL I V G Y+C + A YV + V + + G+ RC V P + I + + + + + +L I S + + G Y C A L+ E + +S + P QV R GE L+C + G+ +W N++D + LV+ +I + G Y C GSS +++ V E ++ PP V EG++++ +C V P ++KW+ GL+ +N Q++ + +++A D+G YICT NG + + + + S ++I P V+ G+ C N G E+ TNN P+
Sbjct: 1623 FQWSREDGRPISSSAERRRQGEELHFPGIQSNDAGVYICTCRD----QRSSNRSKAEIVVATLPSKPIEVFIEEPKAQSVRVGSTVSFICT-----AKSKLPAYTLVWTRKGNGKLPNRAMDFNGILTIQNVQPEDAGIYVCTGSNMLGMDEGSAVLYVPAAEGVQPVATLSPPVQTVKEGDVAQFRCTVTGNPTPAVEWIGGSGKRISSKAVIRNGQLTISSVDRSDEGEYICKA--------LNTHGEHTARGVLHVQSTGQPNGLPHVQVSPQRVEIYEGETLRLYCR---AIGSPTPSLKW---------------NKMDRTDIGTLVVPNIRLSDAGTYLCVGTNAAGSSEAHIDVSVTKGENILSGVIIQPPSASVIEGEALDLNCLV---PGTSTGSVKWSRAG--GLLSSN-----HQVLETRLR-------ILRASADDTGDYICTVENGPSPQKATVSVSVTSSASRLQTPIISIEPHSAVVKQGESASFRCKVHN--GAQPVRLEWKLTNNLPL 2093 HSP 4 Score: 71.633 bits (174), Expect = 4.105e-12 Identity = 84/339 (24.78%), Postives = 138/339 (40.71%), Query Frame = 3
Query: 768 IKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEF-------IGNDQELV-IKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYI---NGKKFKNGDIP---------LVNRLD--GQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNS-LTITPREIRVRAGQRVDIECFSKNT 1715
I I + A+ + GE S RC+V Q ++ W + +G D ++ + + + N GTY+CVAS L M SI RES + T GP V V G+ L C+ ++G W+ N K + +P LV R + G YV +Q N+G E RV ++ + + + P++ V EG + HC P + W E R+++P W+ +I D + ++L DSG Y+C N SE+ ++ + D T P ++ VR G+ + ++C + T
Sbjct: 2053 ISIEPHSAVVKQGESASFRCKVHNGAQPVRLEWKLTNNLPLPDNVKVGPDSSIMTVTNAQAKNQGTYRCVAS------NLYGMTHSIVSL-IVRESPKAVVTPAGP-VRVRVGDPINLECQ---AAGEPRPSVRWHRLDNNRKTMLSSTVPVDSSAIIQVLVARPEDSGTYVCS------AQNNQGTTETRVEVFVEGGPQVPTVPRASVRE--PMIIVVEGSTATLHCDAHGFP---KPTITWFKE------RSSLP---WR---HKIVDNS--LILPNVGRQDSGQYVCNATN-HLGTSEVTIMLEVDTPPYATSLPNDVSVRVGEVIRLQCLAHGT 2354
BLAST of low density lipoprotein receptor-1 vs. Ensembl Zebrafish
Match: lrp2b (low density lipoprotein receptor-related protein 2b [Source:ZFIN;Acc:ZDB-GENE-111115-1]) HSP 1 Score: 82.8037 bits (203), Expect = 1.592e-15 Identity = 74/251 (29.48%), Postives = 103/251 (41.04%), Query Frame = 3
Query: 1575 TEPNGQTARSELIVIPDKDKNSLTITPRE-----IRVRAGQR--VDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTA-PGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
T P T ++ + + D NS+ + I +R G ++I+ +S + Q S N P GR F PA R+ P G+ L +N D C + + D P C G C+ N CD +N C DK+DE T C P + C N +P + W CDG +DCG+G DE NC C F C++ IP+ +VCD DC G DE C S
Sbjct: 909 THPFSLTIHTDHLFVSDWRTNSVFRMRKRDGGDNIMLRKGISGIMNIKAYSADLQDLFK-----SRCNMIPNGRCSHFCFPT--PASSRVCGCPFGMKLQENQRD--CVKDDSEPPPDDNCGDYAFP----CDGGRCVPNTYRCDGVNDCVDKTDEVNCTLPGATCSPYAFTCG-NKHCIPAR------WRCDGHDDCGDGSDETNCPTRGPTTCSSSQFACTNGNCIPKTWVCDAFNDCGDGSDERHCNS 1139 HSP 2 Score: 69.707 bits (169), Expect = 1.656e-11 Identity = 44/118 (37.29%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1938 RFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
+ C NG C NA+ C+ I C D SDE T R C +C N +P + ++CD +DCG+ DEQNC+ C G F CS+ + +P+ +VCD DC DE GC
Sbjct: 147 KTCANGACYNNAQHCNGILDCRDGSDESNCT-RHCQSHQFECA-NGFCIP------MPFVCDHWDDCGDNSDEQNCE---YRTCSGSEFACSNGRCMPQQWVCDGINDCGDFSDENGC 253 HSP 3 Score: 67.781 bits (164), Expect = 6.298e-11 Identity = 45/137 (32.85%), Postives = 57/137 (41.61%), Query Frame = 3
Query: 1893 VSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQ-NCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
+ V C G C NG+C+ CD C D SDE C KC + +P + ++CDGE DC +G DEQ C G C FTC + + IP+ Y CD DC DE C P
Sbjct: 15 IHGPYIVQGQCMSGEFQCSNGQCINQDWKCDGTKDCTDNSDELNCPLPTCSSQEFKCLTGGECIP------LEFVCDGEADCADGSDEQRTCSG---QTCSPDQFTCREGQCIPKQYNCDHVPDCVDNSDENNCNYP 142 HSP 4 Score: 66.6254 bits (161), Expect = 1.371e-10 Identity = 44/117 (37.61%), Postives = 60/117 (51.28%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRE--CDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
N C+ CD N C D SDE+ TC E CDP+ +C+ N++ +P I W CDG DCG+G DE+NC+ C + C + + IP +VCD + DC DE C
Sbjct: 3682 NYRCIPLWAVCDGTNDCLDNSDEN--TCHELTCDPLGDFRCD-NHRCVP------IRWRCDGSNDCGDGSDERNCEP---RPCSESEYRCDNQQCIPGAWVCDHDNDCGDNSDERDC 3786 HSP 5 Score: 63.5438 bits (153), Expect = 1.214e-9 Identity = 45/125 (36.00%), Postives = 53/125 (42.40%), Query Frame = 3
Query: 1923 CPPGY----RF-CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
CPP Y +F CQ+G C CD C D SDED C + +C N K+ I W CDG DC +G DE+ D C F C IP+ YVCD DC DE
Sbjct: 3541 CPPHYCKTGQFQCQDGNCTNPFFLCDGHKDCFDGSDEDAALCSD-----HRCTENQFQCKNKHCIPITWHCDGVVDCSDGSDEET-DSCIDKTCKPGQFQCKKGGCIPQSYVCDAQNDCGDNSDE 3659 HSP 6 Score: 63.5438 bits (153), Expect = 1.245e-9 Identity = 43/129 (33.33%), Postives = 60/129 (46.51%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH-W-ICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
+ C PG C+ G C+ + CD N C D SDE C D KC+ + + K NY I W +CDG DC + DE C + + G F C +++ +P + CD + DC G DE C
Sbjct: 3624 IDKTCKPGQFQCKKGGCIPQSYVCDAQNDCGDNSDEPYEVCMGPD---YKCDPDTEFPCKGNYRCIPLWAVCDGTNDCLDNSDENTCHELTCDPLGD--FRCDNHRCVPIRWRCDGSNDCGDGSDERNC 3747 HSP 7 Score: 63.1586 bits (152), Expect = 1.564e-9 Identity = 50/161 (31.06%), Postives = 60/161 (37.27%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDP-------------ITCR-------ECDPIS---------------------RKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C P C NG C++ + CD N C D SDE TC C P+S R C +N L+ + CD DCG+G DE NC N C + FTC + IP YVCD IDC G DE
Sbjct: 2899 CSPQQFNCANGNCIQQSWVCDGNNDCGDNSDEAQELQCGSRTCNPGDFTCPSWYPGSPRCIPLSYVCDGEKDCVDAADELHNCPNRTCHLNEFACANGRCILLPFHCDRVNDCGDGSDETNC---IYNTCSSREFTCQNGVCIPSTYVCDGYIDCQDGSDE 3056 HSP 8 Score: 61.2326 bits (147), Expect = 6.921e-9 Identity = 45/149 (30.20%), Postives = 63/149 (42.28%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLP 2390
C NG C+ CD + C D SDE R C C N + +P++ W+CDG DCG+ DE CD + G++ + +P VCDE+ DC G DE+ T+ + Q L+CE P P
Sbjct: 187 CANGFCIPMPFVCDHWDDCGDNSDEQNCEYRTCSGSEFACS-NGRCMPQQ------WVCDGINDCGDFSDENGCDPGIRDCYPGEWPCPGSSLCVPVNKVCDEHPDCPGGTDESNATA---------HLTCDLHQCSALSCEYRCHPTP 319 HSP 9 Score: 61.2326 bits (147), Expect = 7.039e-9 Identity = 41/127 (32.28%), Postives = 59/127 (46.46%), Query Frame = 3
Query: 1935 YRF-CQNG-ECLENAKFCDKINHCADKSDEDPITCRE---CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
Y F C +G +C+ + CD + C D SDE R C +C+++ +PK+ W CDG DC +G DE N G C F C++ + + +VCD DC DET C +P
Sbjct: 1185 YEFACASGDQCVSQSYRCDGVYDCKDHSDESGCPTRRPGLCHDNEFQCQVDGFCIPKE------WECDGHPDCVDGSDEHN--GCPPRTCSSVQFQCANGNCVSKNWVCDGENDCRDMSDETNCPTP 1303 HSP 10 Score: 61.2326 bits (147), Expect = 7.039e-9 Identity = 41/125 (32.80%), Postives = 59/125 (47.20%), Query Frame = 3
Query: 1929 PGYRF-CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH-WICDGEEDCGNGYDEQ--NCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
P ++F C N C+ CD N C D+SDE C + CE+ + Y + +C+ ++DCG+G DE+ C +L C F CS+ +P YVCD N +C DE GC
Sbjct: 3836 PAHQFQCNNKLCVNQQWVCDGFNDCGDRSDEQLSLC-----WNITCEMPTKFRCDNGYCIYSGLMCNQKDDCGDGSDEKEDQCQEPTLAPCTPNEFKCSNGHCVPLPYVCDHNNNCGDLTDELGC 3955 HSP 11 Score: 59.6918 bits (143), Expect = 1.768e-8 Identity = 39/124 (31.45%), Postives = 59/124 (47.58%), Query Frame = 3
Query: 1923 CPPGYRFCQNGE-CLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDET 2285
C PG C C+ ++ CD N+C D SDE+P+ C R C +C+ + + +P+ W+CD DC +G DE + C + F C++ I + +VCD N DC DE
Sbjct: 2815 CAPGLVKCDTTNICIPSSSLCDGHNNCGDNSDENPLFCAGRTCSADEFRCD-SGKCIPQ------FWVCDRISDCLDGTDEPPTCEDHIYTCSPQQFNCANGNCIQQSWVCDGNNDCGDNSDEA 2931 HSP 12 Score: 59.3066 bits (142), Expect = 2.417e-8 Identity = 40/124 (32.26%), Postives = 54/124 (43.55%), Query Frame = 3
Query: 1926 PPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
P G C N C+ CD N C D SDE R C +C+ N Q +P W+CD + DCG+ DE++C+ L C F C+ IP C+ DC DE+ C +
Sbjct: 3714 PLGDFRCDNHRCVPIRWRCDGSNDCGDGSDERNCEPRPCSESEYRCD-NQQCIPGA------WVCDHDNDCGDNSDERDCE---LRTCRPGTFQCTSGHCIPEALKCNGYADCLDFSDESTCPT 3827 HSP 13 Score: 55.8398 bits (133), Expect = 2.970e-7 Identity = 41/122 (33.61%), Postives = 51/122 (41.80%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRE----CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC-----SDNKTIPRGYVCDENIDCSQGEDE 2282
C +G+C+ CD+I+ C D +DE P TC + C P C N I W+CDG DCG+ DE C FTC + IP YVCD DC DE
Sbjct: 2864 CDSGKCIPQFWVCDRISDCLDGTDEPP-TCEDHIYTCSPQQFNCANGNCIQQS-------WVCDGNNDCGDNSDEAQELQCGSRTCNPGDFTCPSWYPGSPRCIPLSYVCDGEKDCVDAADE 2977 HSP 14 Score: 53.5286 bits (127), Expect = 1.581e-6 Identity = 39/120 (32.50%), Postives = 52/120 (43.33%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C PG C +G C+ A C+ C D SDE TC P R C + K W+CDG DCG+ DEQ +++ F C + I G +C++ DC G DE
Sbjct: 3791 CRPGTFQCTSGHCIPEALKCNGYADCLDFSDES--TCPTRYPGGRWCPAHQFQCNNKLCVNQQWVCDGFNDCGDRSDEQLSLCWNITCEMPTKFRCDNGYCIYSGLMCNQKDDCGDGSDE 3908 HSP 15 Score: 51.9878 bits (123), Expect = 4.247e-6 Identity = 48/179 (26.82%), Postives = 61/179 (34.08%), Query Frame = 3
Query: 1878 LEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDE----------------------------------------DPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQN--CDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
L+G ++ C P C NG C+ CD N C D SDE D + C R C P KC+ N +P + +CDG +CG+ DE C G C F C K IP+ +VCD DC G DE
Sbjct: 2719 LDGSDELERVCAFHTCSPTEFTCDNGGCVPLYYVCDYTNDCGDNSDEHGCPFPTCNPSTEFTCANGRCISAAYVCDGINDCRDNGTTDEVNCPDRTCAPGLVKCDTTNICIPSSS------LCDGHNNCGDNSDENPLFCAG---RTCSADEFRCDSGKCIPQFWVCDRISDCLDGTDE 2888 HSP 16 Score: 51.6026 bits (122), Expect = 5.565e-6 Identity = 53/161 (32.92%), Postives = 70/161 (43.48%), Query Frame = 3
Query: 1809 AHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIY-VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
+H L PGG D F L + KI V+D +R N +C+ CD + C D SDE P TC C +C+ N P +FL CDG +DC +G DE + S + C F C + IP + CD +DCS G DE
Sbjct: 3470 SHLCLIGPGGTEARCECPDHFIGLA---IGFKIQCVADCSSTQFRCGDNEKCIPIWWKCDGQSDCGDGSDE-PQTCPPHYCKTGQFQCQDGNCTNP---FFL----CDGHKDCFDGSDE-DAALCSDHRCTENQFQCKNKHCIPITWHCDGVVDCSDGSDE 3618 HSP 17 Score: 51.6026 bits (122), Expect = 6.055e-6 Identity = 38/128 (29.69%), Postives = 51/128 (39.84%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCS-DNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C PG+ C + C+ N+ CD C D SDE C C +Q + + + CDG DC + DE C C F C D IP+ + CD + DC G DE P+
Sbjct: 1144 CQPGFFLCPDHRCIYNSYVCDGDQDCLDGSDEKDCV-YTCGTYEFACASGDQCVSQS------YRCDGVYDCKDHSDESGCPTRRPGLCHDNEFQCQVDGFCIPKEWECDGHPDCVDGSDEHNGCPPR 1264
BLAST of low density lipoprotein receptor-1 vs. Ensembl Zebrafish
Match: lrp2a (low density lipoprotein receptor-related protein 2a [Source:ZFIN;Acc:ZDB-GENE-050119-2]) HSP 1 Score: 80.4925 bits (197), Expect = 9.594e-15 Identity = 47/128 (36.72%), Postives = 64/128 (50.00%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C G+ C G C+ ++ CD N C+D SDE C+ +C + + +P+ HW+CD EEDC +G DE Q+C G C FTC++ IP GY CD DC G DE C P+
Sbjct: 2 CESGFFRCGTGRCIPVSQRCDGTNDCSDNSDEIGCPQPTCESAQFQCLSDGECIPQ------HWVCDDEEDCEDGSDERQHCPG---RTCSSSQFTCTNGACIPGGYRCDRVPDCLDGADERNCFYPE 120 HSP 2 Score: 80.1073 bits (196), Expect = 1.290e-14 Identity = 72/264 (27.27%), Postives = 111/264 (42.05%), Query Frame = 3
Query: 1521 SFIVLMKAEVSDS--GYYIC---TEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH-WICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
S I+ +K+ +DS G+ C T PNG + P + + P +++ A Q+ ++ S G+ FS +N K + ++ V H DN+ + C ++ C P C N C+ + CD N C D SDE R+C + +Q + +Y + W+CD + DCG+G DE NCD S+ C F C D++ I YVCD + DC+ G DE GC
Sbjct: 926 SHIMHVKSFNADSQIGFNFCSRQTNPNGDCSH---FCFPAPNSQRVCGCPYGMKLEANQQTCVDDPSNEPPTLQCGSNSFSCSNGKCVPHS--YQCDGVDDCH------------DNSDEAHCGAH----------NNTCSPLAFTCANQRCVPRSWHCDGHNDCFDGSDE-----RDCPTQTPGTCPADQFICANHYCIPRTWLCDTDNDCGDGSDENNCD--SIGTCYPGQFQCPDHRCIDPNYVCDGDRDCADGADEQGCV 1155 HSP 3 Score: 75.485 bits (184), Expect = 2.739e-13 Identity = 41/120 (34.17%), Postives = 62/120 (51.67%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C NG+C+ ++ CD ++ C D SDE C P++ C N + +P+ W CDG DC +G DE++C + C F C+++ IPR ++CD + DC G DE C S
Sbjct: 1004 CSNGKCVPHSYQCDGVDDCHDNSDEAHCGAHNNTCSPLAFTCA-NQRCVPRS------WHCDGHNDCFDGSDERDCPTQTPGTCPADQFICANHYCIPRTWLCDTDNDCGDGSDENNCDS 1116 HSP 4 Score: 70.0922 bits (170), Expect = 1.201e-11 Identity = 46/129 (35.66%), Postives = 67/129 (51.94%), Query Frame = 3
Query: 1914 SDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH-W-ICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
S C PG C+NG C+ N CD + C D SDE PI EC + +C+ + + + NY + W +C+G DC + DEQNC+ + G F C +++ IP + CD + DC G DE C+
Sbjct: 3628 SRTCRPGQFKCRNGRCIPNTWKCDVDDDCGDNSDE-PI--EECMGPAYRCDNHTEFDCRTNYRCVPLWAVCNGHNDCRDNSDEQNCEELTCEPSGD--FRCDNHQCIPLRWRCDGDNDCGDGSDELNCS 3751 HSP 5 Score: 70.0922 bits (170), Expect = 1.286e-11 Identity = 43/120 (35.83%), Postives = 63/120 (52.50%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C NG C ++ CD++ +C D SDE T R C +C N + +P+ +ICD ++DCG+ DEQNC + C G +FTC + I + ++CD DC DE GC + Q
Sbjct: 126 CANGACFNRSQRCDQVLNCRDGSDEANCTQR-CSSGQFQCS-NGECIPRG------YICDHDDDCGDRSDEQNC---TYPTCRGTYFTCPSGRCIHQVWLCDGEDDCEDNADEKGCDNVQ 234 HSP 6 Score: 68.9366 bits (167), Expect = 2.969e-11 Identity = 44/121 (36.36%), Postives = 60/121 (49.59%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDP---ITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
C +G C+ ++ CD N C D SDED R C C +NN+ P++ W+CDG+ DC + +DE QNC + +C FTC++ I Y CD DC DE GCT
Sbjct: 2910 CDDGRCIASSWICDGDNDCGDMSDEDQRHNCANRTCSAQEFTC-VNNRP-PQRKCIPRDWVCDGDADCSDAFDEHQNC---TRRSCSTNEFTCNNGLCIRSSYRCDRRNDCGDSSDEQGCT 3025 HSP 7 Score: 68.1662 bits (165), Expect = 4.849e-11 Identity = 45/140 (32.14%), Postives = 60/140 (42.86%), Query Frame = 3
Query: 1878 LEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
L R S + + C G C NGEC+ CD + C D+SDE T C C P W+CDGE+DC + DE+ CD G++ S IP ++CD + C GEDET T+
Sbjct: 142 LNCRDGSDEANCTQRCSSGQFQCSNGECIPRGYICDHDDDCGDRSDEQNCTYPTCRGTYFTC-------PSGRCIHQVWLCDGEDDCEDNADEKGCDNVQRECYPGEWPCPSSGVCIPFDHLCDGTVHCPDGEDETNITA 274 HSP 8 Score: 68.1662 bits (165), Expect = 5.412e-11 Identity = 48/152 (31.58%), Postives = 69/152 (45.39%), Query Frame = 3
Query: 1851 DNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDE--QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
D N D + ++ S CPP C+N C++ CD N C D SDE+ C + CDP R +C+ N I H +C+ +DCG+G DE ++C + C + C + + IP Y CD+ DC DE GC
Sbjct: 3814 DGNADCLDFTDESSCPTRYPNSTYCPPFLFECKNHVCVQQHWICDGDNDCGDNSDEELHLCLDISCDPPFRFRCDNNRCIYS-------HEVCNSIDDCGDGTDERAEHCVTPTHGPCSADEYKCGNGQCIPLQYACDDYDDCEDQSDELGC 3958 HSP 9 Score: 67.3958 bits (163), Expect = 9.457e-11 Identity = 45/122 (36.89%), Postives = 58/122 (47.54%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC----RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDN-----KTIPRGYVCDENIDCSQGEDE 2282
C +G C+ +CD C D SDE PITC R C+ +C+ I WICDG+ DCG+ DE + C + FTC +N K IPR +VCD + DCS DE
Sbjct: 2868 CSSGRCIPGHWYCDGGTDCNDGSDE-PITCTSLVRTCNSEQFRCDDGRCIASS-------WICDGDNDCGDMSDEDQRHNCANRTCSAQEFTCVNNRPPQRKCIPRDWVCDGDADCSDAFDE 2981 HSP 10 Score: 62.7734 bits (151), Expect = 1.983e-9 Identity = 39/117 (33.33%), Postives = 56/117 (47.86%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG C+ ++ CD+ N C D SDE T + C C+ N + + + ++CDG+ DCG+ DE + C F C + +P+ VCD N DCS DE GC
Sbjct: 2997 CNNGLCIRSSYRCDRRNDCGDSSDEQGCTYQPCQQHQFTCQ-NGRCISRD------FLCDGDNDCGDESDELDHLCRMPAPTCPSGHFRCDNGNCVPQSQVCDRNDDCSDNSDEKGC 3106 HSP 11 Score: 61.2326 bits (147), Expect = 6.752e-9 Identity = 39/124 (31.45%), Postives = 57/124 (45.97%), Query Frame = 3
Query: 1926 PPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
P G C N +C+ CD N C D SDE + R C +C+ N +P + W+CD + DC + DE++C+ L C +F C+ I + CD N DC DE+ C +
Sbjct: 3717 PSGDFRCDNHQCIPLRWRCDGDNDCGDGSDELNCSPRPCTESEYRCD-NLHCIPDR------WVCDHDNDCEDNSDERDCE---LRTCHPGYFQCASGHCIAERFKCDGNADCLDFTDESSCPT 3830 HSP 12 Score: 60.8474 bits (146), Expect = 9.875e-9 Identity = 40/119 (33.61%), Postives = 53/119 (44.54%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C NG C+ CD++ C D +DE EC + +C N + CD +C +G DE NC C F CS+ + IPRGY+CD + DC DE CT P
Sbjct: 89 CTNGACIPGGYRCDRVPDCLDGADERNCFYPECSEL--RCA-NGACFNRSQR------CDQVLNCRDGSDEANC----TQRCSSGQFQCSNGECIPRGYICDHDDDCGDRSDEQNCTYP 194 HSP 13 Score: 60.4622 bits (145), Expect = 1.294e-8 Identity = 38/121 (31.40%), Postives = 50/121 (41.32%), Query Frame = 3
Query: 1923 CPPGYRFCQNGE-CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C P + CQ+ C+ + CD N C D SDE P C + C N HW CDG DC +G DE + C + F C D + I ++CD + DC DE
Sbjct: 2819 CQPEHTKCQSTNICIPRSYLCDGDNDCGDNSDESPTHC-----ATSTCSHNEFRCSSGRCIPGHWYCDGGTDCNDGSDEPITCTSLVRTCNSEQFRCDDGRCIASSWICDGDNDCGDMSDE 2934 HSP 14 Score: 58.9214 bits (141), Expect = 3.597e-8 Identity = 53/184 (28.80%), Postives = 71/184 (38.59%), Query Frame = 3
Query: 1887 RQVSSKIYVS--DICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDP-----------ISR-------------------------------KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQ--NCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE-TGCTS 2297
RQ ++ I +S C P C NG C+ CD N C D SDE R CDP I+R KC+ N +P+ ++CDG+ DCG+ DE +C + + C F CS + IP + CD DC+ G DE CTS
Sbjct: 2724 RQAAAFISLSAFHTCEPTVFTCGNGRCVPYHYRCDHYNDCGDNSDETGCIFRPCDPNTEFSCNNGRCIAREYICNGINNCYDNGTSDEQNCPERTCQPEHTKCQSTNICIPRS------YLCDGDNDCGDNSDESPTHC---ATSTCSHNEFRCSSGRCIPGHWYCDGGTDCNDGSDEPITCTS 2898 HSP 15 Score: 58.5362 bits (140), Expect = 4.083e-8 Identity = 43/121 (35.54%), Postives = 55/121 (45.45%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE--QNCDGFSLNNCGGKFFTCSDN-KTIPRGYVCDENIDCSQGEDETGC 2291
C N C+ A CD N C D SDEDP C R C P KC N + +P W CD ++DCG+ DE + C G + F C N + +P VC+ + DC DE C
Sbjct: 3597 CANKRCISEAWQCDGENDCGDGSDEDPAHCSSRTCRPGQFKCR-NGRCIPNT------WKCDVDDDCGDNSDEPIEECMGPAYRCDNHTEFDCRTNYRCVPLWAVCNGHNDCRDNSDEQNC 3710 HSP 16 Score: 58.5362 bits (140), Expect = 4.958e-8 Identity = 39/120 (32.50%), Postives = 50/120 (41.67%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C G C +G C C+ C D SDED + C + +CE + K W CDGE DCG+G DE S C F C + + IP + CD + DC DE
Sbjct: 3549 CRLGQFQCNDGNCTSPHFLCNSNQDCPDGSDEDTVLC-----ATHQCESHQWQCANKRCISEAWQCDGENDCGDGSDEDPAH-CSSRTCRPGQFKCRNGRCIPNTWKCDVDDDCGDNSDE 3662 HSP 17 Score: 57.7658 bits (138), Expect = 7.629e-8 Identity = 41/129 (31.78%), Postives = 60/129 (46.51%), Query Frame = 3
Query: 1932 GYRF-CQNG-ECLENAKFCDKINHCADKSDEDPITCRE---CDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
Y F C NG +C+ + CD + C D+SDE R C S +C+ + +P ++W CDG DC +G DE + C F C + + RG++CD + DC G DE C +P
Sbjct: 1160 AYEFKCANGHQCVNSYYRCDGVFDCNDRSDESGCPTRPPGMCHHESEFQCQSDGSCVP------VNWECDGHPDCEDGSDEHH--ACPPRTCPTTQFRCDNGNCVYRGWICDGDNDCRDGSDERDCPTP 1280 HSP 18 Score: 56.6102 bits (135), Expect = 1.577e-7 Identity = 45/136 (33.09%), Postives = 60/136 (44.12%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCR-----ECDPISRKCEINNQILPKKNYFLI--HWICDGEEDCGNGYDEQNCDGFSLNNCGGKF-FTCSDNKTIPRGYVCDENIDCSQGEDETG--CTSP 2300
C PGY C +G C+ CD C D +DE R C P +C KN+ + HWICDG+ DCG+ DE+ + +C F F C +N+ I VC+ DC G DE C +P
Sbjct: 3794 CHPGYFQCASGHCIAERFKCDGNADCLDFTDESSCPTRYPNSTYCPPFLFEC---------KNHVCVQQHWICDGDNDCGDNSDEELHLCLDI-SCDPPFRFRCDNNRCIYSHEVCNSIDDCGDGTDERAEHCVTP 3919
BLAST of low density lipoprotein receptor-1 vs. Ensembl Xenopus
Match: sel1l (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase [Source:Xenbase;Acc:XB-GENE-973992]) HSP 1 Score: 124.79 bits (312), Expect = 2.981e-28 Identity = 80/220 (36.36%), Postives = 104/220 (47.27%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNC--DGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS-NDFQVILK 2591
C NG+C+ CD C D SDE + C P CE N L W CDG+ DCG+G DE NC G S + C F C +T IP Y CD+ DC DE GC PQ+ ++A++ V TC A G P P++ WR NWG I S+R S + +L I+D K D G Y CEA++++ F D +ILK
Sbjct: 259 CPNGQCIPRDYLCDGEKDCKDGSDE--MHCGTPSP----CEPNEFKCKNGRCALKLWRCDGDNDCGDGSDELNCPTKGPS-DTCAPDQFVCVQARTCIPASYQCDDEADCPDRSDEVGCNPPQVITPPEESIMASRGDTVRFTCVAIGVPTPIITWRLNWGHIPTSSRVSMT-----SENGHGTLIIRDVKEADQGAYTCEAINAKGMVFGIPDGVLILK 466 HSP 2 Score: 72.4034 bits (176), Expect = 4.037e-12 Identity = 93/436 (21.33%), Postives = 160/436 (36.70%), Query Frame = 3
Query: 492 IDILPEES-LKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQN-------KTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPA-LFRYGERFSLRCEVEPFYQNIKYTWYKK------DEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV----GSSIKEVNLIVL---LDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVI----------PDKDKNSLTITPREIRVRAGQRVDIECF 1703
+ I P+++ L GG++ +C G P + + W + K +G L V + G YIC +S ++ +A V+ S + + R G + C + W ++ D + + L I+ + ++ G Y C S D+ E + + + Q+ V RG+ E C T++G EW NG + + G +L + +EG Y CRV G V+L V L E ++ SP +V+EG +V +CR P+ + W KEG ++P + S + +++A +DSG YIC NG + I+I P + +L I P + GQ +++ C
Sbjct: 1590 LRIHPQKATLSPGGEVTLRCHVSGNP------PYYFYWTREDGRPIPPSAKAVGEGENLHFSRVQPTDSGVYICTCRSPDSVNTSKAEILVSAAPSKPITVTVEEQRVQTVRPGSDVTFICTAKSKSPAYTLVWTRQHNRKLPDRAMDFNGILTIRRVQPEDAGIYVCTGS-----NMYDMDEGNATLYVQAGTATSPNAAAEPRQLTVQRGQTAEFRC---TATGTPTPAVEW-----TGPNGGLSPRAVVQG---GVLRFHSVEPSDEGQYTCRVHNSAGQHFARVDLRVHSGSLPE--VQVSPERTEVREGDTVRLYCRAGGTPAA---TISWR---KEG---GSLPPQAY----------GSKLRILQASTADSGEYICRVTNGAATQQASIIITITRSSGPQQPSGNVPALRIEPSSDTLVEGQTLELNCL 1982 HSP 3 Score: 59.3066 bits (142), Expect = 3.528e-8 Identity = 92/432 (21.30%), Postives = 158/432 (36.57%), Query Frame = 3
Query: 510 ESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTN--ILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSV----------SYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKD--------EFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV----GSSIKEVNLIV---LLDEG--LIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTIT-PREIRVRAGQRVDIECFSKNT 1715
E++++G I+ C G P + + N + + ILQ D + YIC+ S S+ EA+ +N+ S S I I + A + G+ + +C + Q I+ TW + N + I N G+Y+C+AS ++ S+ R S ++ P ++ V GE + C G+ W G + +N + LDG I + G+Y C GS+ V + V ++ G L+ P+ V G C P+ + W+ +R +P WQ ++ + T +++ DSG YIC N +E+ V D + + T P E V G+ + I+C + T
Sbjct: 2164 ETVELGQTIELNCLAEGHPGAVVTWHRSGGLPLPSNHQVSGSRMRILQASPADSGI---YICRVSSASGSQ--EASVTINVHSSAQGEPGDARLQSPVISIDPHSATVQRGQNATFKCRIHDGAQPIRVTWQMRHNQPMEDNVHISPNGSIITIVGATHKNQGSYRCMAS-----NAYGMVHSSVNLVVQGRPS---VSVIPHGKIRVKEGEPINVEC---MGIGDPRPIVSWRRTGAR-ENLKQHRLAPLDG------TIPSAKPADSGSYTCVAHNPHGSTQVHVEVHVEGHVISPGAPLVLADKPVHVVVTGGQATLSCSASGNPTP---TITWS------KLRAPLP---WQ---HQVVNNT--LIIPNVAQQDSGQYICNASNAD-GHAEVYVTLDVETPAYATTLPHEASVSPGEPIQIQCLAHGT 2554 HSP 4 Score: 58.9214 bits (141), Expect = 4.864e-8 Identity = 92/434 (21.20%), Postives = 148/434 (34.10%), Query Frame = 3
Query: 357 NRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNI----LQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLL---DEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRW-QLMNDEIADQ---TSFIVLMKAEVSDSGYYICTEPNGQ---TARSELIV 1616
N L I ++ +QD G Y C+ + + L + P+ + + E S+ G I+ QC G P + W G +I L I S G Y C ++K+ + + + S FRY F + + K D D L I K + GTY+CV ++ S K + Q + K+ + + Q V G E C + G+ + W G + +P + G L I + Q + G Y C + + EV V+L I P + ++ G + F C P +PD W +L D +D + + ++ + D+G Y+CT N Q TA S L V
Sbjct: 2489 NNTLIIPNVAQQDSGQYICNASNADGHAEVY---VTLDVETPAYATTLPHEASVSPGEPIQIQCLAHGTP------PIKFQWSRVDGTLPGQASIQDGVLHIDQASASDSGTYRC----VASNKVGSSEAFAQVTVSGGGAETGTAGSRFFRYC-FFPIIPIIRSGRLGSKVNGSLPDRATVRDSTLHINLAKAADAGTYRCVVGNKVGSSK------TFAQVSVLALPKVRINIRTSVQT-VLAGNSVEFEC---LALGDPRAKVTWSKVGSR-----LPADAVISG---GTLRIEQVKQSDAGQYRCTAANDVGEVQSHVILHVQSVPQIAAQPEMKEITAGSTAVFPCLASGFP---------------------VPDITWSKLEGDLPSDHQIDNNVLTILSVKPEDAGTYVCTAANRQGRVTAFSMLKV 2869
BLAST of low density lipoprotein receptor-1 vs. Ensembl Xenopus
Match: sel1l (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase [Source:Xenbase;Acc:XB-GENE-973992]) HSP 1 Score: 123.635 bits (309), Expect = 7.300e-28 Identity = 80/222 (36.04%), Postives = 105/222 (47.30%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCD--GFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS-NDFQVILKNN 2597
C NG+C+ CD C D SDE + C P CE N L W CDG+ DCG+G DE NC G S + C F C +T IP Y CD+ DC DE GC PQ+ ++A++ V TC A G P P++ WR NWG I S+R S + +L I+D K D G Y CEA++++ F D +ILK +
Sbjct: 226 CPNGQCIPRDYLCDGEKDCKDGSDE--MHCGTPSP----CEPNEFKCKNGRCALKLWRCDGDNDCGDGSDELNCPTKGPS-DTCAPDQFVCVQARTCIPASYQCDDEADCPDRSDEVGCNPPQVITPPEESIMASRGDTVRFTCVAIGVPTPIITWRLNWGHIPTSSRVSMTS-----ENGHGTLIIRDVKEADQGAYTCEAINAKGMVFGIPDGVLILKPH 435 HSP 2 Score: 73.9442 bits (180), Expect = 1.154e-12 Identity = 104/461 (22.56%), Postives = 168/461 (36.44%), Query Frame = 3
Query: 492 IDILPEES-LKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQN-------KTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPA-LFRYGERFSLRCEVEPFYQNIKYTWYKK------DEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV----GSSIKEVNLIVL---LDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYIC---TEPNGQTARSELIVIPDK-DKNSLTITPREIRVRAGQRVDIECFSKN-----TQGRASGNPEFSFTNNKPIGRDG 1781
+ I P+++ L GG++ +C G P + + W + K +G L V + G YIC +S ++ +A V+ S + + R G + C + W ++ D + + L I+ + ++ G Y C S D+ E + + + Q+ V RG+ E C T++G EW NG + + G +L + +EG Y CRV G V+L V L E ++ SP +V+EG +V +CR P+ + W KEG ++P D S +V+ +D G Y+C + AR E+IVI +L I P V GQ V++ C S N T R G P + N +G G
Sbjct: 1540 LRIHPQKATLSPGGEVTLRCHVSGNP------PYYFYWTREDGRPIPPSAKAVGEGENLHFSRVQPTDSGVYICTCRSPDSVNTSKAEILVSAAPSKPITVTVEEQRVQTVRPGSDVTFICTAKSKSPAYTLVWTRQHNRKLPDRAMDFNGILTIRRVQPEDAGIYVCTGS-----NMYDMDEGNATLYVQAGTATSPNAAAEPRQLTVQRGQTAEFRC---TATGTPTPAVEW-----TGPNGGLSPRAVVQG---GVLRFHSVEPSDEGQYTCRVHNSAGQHFARVDLRVHSGSLPE--VQVSPERTEVREGDTVRLYCRAGGTPA---ATISWR---KEG---GSLPPQARTERTD-----ISTLVIPSISAADGGTYLCVGTSSAGSAQARIEVIVIGAPIHGPTLRIEPSSDTVIEGQLVELNCVSANPYATVTWHRGGGRP---LSPNHQVGAYG 1959 HSP 3 Score: 68.9366 bits (167), Expect = 3.851e-11 Identity = 100/492 (20.33%), Postives = 169/492 (34.35%), Query Frame = 3
Query: 321 RWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEE----SLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGN-----TNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKE-----LHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYEC----RVGSSIKEVNLIVL---LDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVI----------PDKDKNSLTITPREIRVRAGQRVDIECF 1703
R + K L+ + D G+Y C+ + ++ L PS I + EE +++ G + C+ ++ +T W Q N+ + + IL I V G Y+C + A YV + S + G+ RC T E+ G + L ++ + V + V + + Q FA + ++ + P QV R E +E L+C + G W G G +P R + +S LVI IS + G Y C GS+ + +IV+ + + P V EGQ VE +C N + W+ L N+ ++ S + +++A +DSG YIC NG + I+I P + +L I P + GQ +++ C
Sbjct: 1577 RPIPPSAKAVGEGENLHFSRVQPTDSGVYICTCRSPDS--VNTSKAEILVSAAPSKPITVTVEEQRVQTVRPGSDVTFICT-----AKSKSPAYTLVWTRQHNRKLPDRAMDFNGILTIRRVQPEDAGIYVCTGSNMYDMDEGNATLYVQAGTATSPNAAAEPRQLTVQRGQTAEFRC-------TATGTPTPAVEWTGPNGGLSPRAVVQGGVLRFHSVEPSDEGQYTCRVHNSAGQHFARV-DLRVHSGSLPEVQVSPERTEVREGDTVRLYCR---AGGTPAATISWRKEG-----GSLPPQARTERTDISTLVIPSISAADGGTYLCVGTSSAGSAQARIEVIVIGAPIHGPTLRIEPSSDTVIEGQLVELNCVSAN----PYATVTWHRGGGRPLSPNH-----------QVGAYGSKLRILQASTADSGEYICRVTNGAATQQASIIITITRSSGPQQPSGNVPALRIEPSSDTLVEGQTLELNCL 2030
BLAST of low density lipoprotein receptor-1 vs. Ensembl Xenopus
Match: sel1l (SEL1L adaptor subunit of ERAD E3 ubiquitin ligase [Source:Xenbase;Acc:XB-GENE-973992]) HSP 1 Score: 121.324 bits (303), Expect = 4.071e-27 Identity = 81/220 (36.82%), Postives = 103/220 (46.82%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNC--DGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS-NDFQVILK 2591
C NG+C+ CD C D SDE + C P CE N L W CDG+ DCG+G DE NC G S + C F C +T IP Y CD+ DC DE GC PQ+ ++A++ V TC A G P P++ WR NWG I S+ S N T L I+D K D G Y CEA++++ F D +ILK
Sbjct: 202 CPNGQCIPRDYLCDGEKDCKDGSDE--MHCGTPSP----CEPNEFKCKNGRCALKLWRCDGDNDCGDGSDELNCPTKGPS-DTCAPDQFVCVQARTCIPASYQCDDEADCPDRSDEVGCNPPQVITPPEESIMASRGDTVRFTCVAIGVPTPIITWRLNWGHIPTSS--SENGHGT--------LIIRDVKEADQGAYTCEAINAKGMVFGIPDGVLILK 404 HSP 2 Score: 71.633 bits (174), Expect = 6.880e-12 Identity = 111/513 (21.64%), Postives = 187/513 (36.45%), Query Frame = 3
Query: 492 IDILPEES-LKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQN-------KTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPA-LFRYGERFSLRCEVEPFYQNIKYTWYKK------DEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV----GSSIKEVNLIVL---LDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYIC---TEPNGQTARSELIVIPDKDKNSLTITPREIRVRA-------GQRVDIECFSKNTQGRASGNPEFSFTNNKPIGR---------DGRFKISNVGPAHK-----RLTAPGGLSLSDNNMDVFCSLEGRQ 1892
+ I P+++ L GG++ +C G P + + W + K +G L V + G YIC +S ++ +A V+ S + + R G + C + W ++ D + + L I+ + ++ G Y C S D+ E + + + Q+ V RG+ E C T++G EW G I L+ + G +L + +EG Y CRV G V+L V L E ++ SP +V+EG +V +CR P+ + W KEG R +I S +V+ +D G Y+C + AR E+IVI + NSL P +R+ GQ +++ C +G P+ T ++ GR R +I PA R+++ G + ++V S +G Q
Sbjct: 1495 VRIHPQKATLSPGGEVTLRCHVSGNP------PYYFYWTREDGRPIPPSAKAVGEGENLHFSRVQPTDSGVYICTCRSPDSVNTSKAEILVSAAPSKPITVTVEEQRVQTVRPGSDVTFICTAKSKSPAYTLVWTRQHNRKLPDRAMDFNGILTIRRVQPEDAGIYVCTGS-----NMYDMDEGNATLYVQAGTATSPNAAAEPRQLTVQRGQTAEFRC---TATGTPTPAVEW-------TGGSIGLIAVVQG---GVLRFHSVEPSDEGQYTCRVHNSAGQHFARVDLRVHSGSLPE--VQVSPERTEVREGDTVRLYCRAGGTPA---ATISWR---KEGGKRTDI----------------STLVIPSISAADGGTYLCVGTSSAGSAQARIEVIVIGGR-SNSLGNGP-AVRIETSSGSVVEGQTLELNCV-------VAGQPDAVVTWHR-AGRLLSPNHQVSGSRMRILQASPADSGIYICRVSSASGSQEASVTINVHSSAQGLQ 1949 HSP 3 Score: 68.9366 bits (167), Expect = 4.466e-11 Identity = 99/463 (21.38%), Postives = 168/463 (36.29%), Query Frame = 3
Query: 366 LYIKSLLKQDEGIYNCSVEKVK-DPQIRFNRTLHLKITIPSISIDILPEESLKI---GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYK-----KDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV----GSSIKEVNLIV-LLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKN 1712
L I S +D G Y C+ + Q++ + ++ P + + E+ L + G + C+ +G P I L Q++ + +T I+ + +S G+YIC + E + +V L + + GE ++C +K+ W K D D L I K + GTY+CV ++ S K + FA I+ G E C T G+ +W G G +P +++ G +L I ++ NEG Y CRV G + + V L++ L + I + V G SVEF C P K + W SK G +L D + + + + + + SD+G Y CT N +++ + + P + AG C +
Sbjct: 2097 LQILSARPEDSGSYTCTAQNPSGSTQVQVEVHVEGRVITPGVP-KVTAEQPLHVVVAGDRASLSCTAVGNPAPKITWSKLRAPLPWQHEIVNDTLIIPKAALQDS--GQYICNASNAEG----YSEVFVTLDVETPPYATTLPDEVSVSVGEVIQIQCLAH-GTSPLKFQWSKVNGSLPDRATVRDSTLHINLAKAADAGTYRCVVGNKVGSSKTFAQVSVLAPFAVRVSPLIDTKAVSG---------TAEFTC---TVVGDPRARIQWSKEG-----GQLPAGHQVQG---GVLRIPNLESGNEGTYTCRVSSRFGQAQESVRLVLQALPKVRINIRTSVQTVLAGNSVEFECLALGDPRAK---VTW---SKVG----------SRLPADAVISGGT-LRIEQVKQSDAGQYRCTAANDVGEVQSHVILHVQSVPQIAAQPEMKEITAGSTAVFPCLASG 2514 HSP 4 Score: 64.3142 bits (155), Expect = 1.131e-9 Identity = 113/497 (22.74%), Postives = 189/497 (38.03%), Query Frame = 3
Query: 312 TSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNC-SVEKVKDPQIRF------NRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGN-TNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSV----SYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIG-------NDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV----GSSIKEVNLIV---LLDEGL--IETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTIT-PREIRVRAGQRVDIECFSKNT 1715
+I W + GK + L I S+ D G Y C Q R R+ L P++ I+ S+ G ++ C G P + L+ ++ G+ ILQ D + YIC+ S S+ EA+ +N+ S S I I + A + G+ + +C + Q I+ F N + I N G+Y+C+AS ++ S+ + K ++ P ++ V GE + C G+ W G + +N + LDG ++L I + G+Y C GS+ +V + V ++ G+ + P+ V G C P+ K + W+ +R +P WQ EI + T +++ KA + DSG YIC N + SE+ V D + T P E+ V G+ + I+C + T
Sbjct: 1797 ATISWRKEGGKRTDIST-LVIPSISAADGGTYLCVGTSSAGSAQARIEVIVIGGRSNSLG-NGPAVRIET-SSGSVVEGQTLELNCVVAGQPDAVVTWHRAGRLLSPNHQVSGSRMRILQASPADSGI---YICRVSSASGSQ--EASVTINVHSSAQGLQSPVISIDPHSATVQRGQNATFKCRIHDGAQPIRAALTPLSLFPTDNVHISPNGSIITIVGATHKNQGSYRCMAS-----NAYGMVHSSVN---LVVQGKC-VSVIPHGKIRVKEGEPINVEC---MGIGDPRPIVSWRRTGAR-ENLKQHRLAPLDG--TAVLQILSARPEDSGSYTCTAQNPSGSTQVQVEVHVEGRVITPGVPKVTAEQPLHVVVAGDRASLSCTAVGNPAPK---ITWS------KLRAPLP---WQ---HEIVNDT--LIIPKAALQDSGQYICNASNAE-GYSEVFVTLDVETPPYATTLPDEVSVSVGEVIQIQCLAHGT 2252
BLAST of low density lipoprotein receptor-1 vs. Ensembl Xenopus
Match: rabggtb (Rab geranylgeranyltransferase subunit beta [Source:Xenbase;Acc:XB-GENE-953600]) HSP 1 Score: 77.411 bits (189), Expect = 1.097e-13 Identity = 69/243 (28.40%), Postives = 97/243 (39.92%), Query Frame = 3
Query: 1575 TEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC---RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
T PNG + P + + P +R+R Q+ + + G+ F N K + P + R G DN+ + C SS+ + C NG+C+ CD N C D+SDE R C S C+ NN+ +P+ W+CD + DCG+G DE NC N C F C D++ I YVCD + DC G DE GCT
Sbjct: 958 TNPNGDCSH---FCYPVPNLQRVCGCPYGMRLRPDQQTCFDDPASEPPTMQCGSYSFPCANGKCV------------PVYDRCD--GVDDCHDNSDEANCGTRNNTCSSRAFT----------CGNGQCIPLNWRCDSHNDCVDRSDEQNCPTQGPRSCSSTSFTCQ-NNRCIPRI------WLCDTDNDCGDGSDELNCS----NTCEPGQFQCPDHRCIDPSYVCDGDKDCVDGSDEMGCT 1162 HSP 2 Score: 70.0922 bits (170), Expect = 1.712e-11 Identity = 43/124 (34.68%), Postives = 60/124 (48.39%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDP----ITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C + C+ + CD N C D SDED + + C P C INN+ P++ W+CDG+ DC + YDE QNC + +C F C++ + + CD DC G DE GC P
Sbjct: 2890 CDDARCIPASWICDGDNDCGDMSDEDQRHNYLCLQSCAPTEFTC-INNR-PPERRCIPQSWVCDGDADCSDAYDEHQNC---TRRSCSSSEFACANGLCVRSNFRCDRRNDCGDGSDERGCIYP 3008 HSP 3 Score: 63.1586 bits (152), Expect = 2.366e-9 Identity = 48/126 (38.10%), Postives = 58/126 (46.03%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C G C NG C+ + CD C D SDE R C +C + I W+CD EEDC +G DEQ+C G C + FTCS + IPR Y CD DC+ G DE C P
Sbjct: 13 CSSGSFRCSNGRCIPLSWRCDGTADCTDNSDEAGCPPRTCSTSQFRCGDGDCITSS-------WVCDDEEDCDDGSDEQHCPG---RTCSAQQFTCSSGQCIPRAYRCDRMKDCTDGADERNCLYP 128 HSP 4 Score: 62.3882 bits (150), Expect = 4.274e-9 Identity = 42/126 (33.33%), Postives = 66/126 (52.38%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLI-HW-ICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
C PG C NG C+ + CD + C D SDE P +EC + +C+ + + NY + W +C+G +DC + DEQ C+ + + G F C +++ IP + CD + DC+ G DE C+
Sbjct: 3613 CNPGQFRCNNGRCIPQSWKCDVDDDCGDHSDE-PF--QECMGPAYRCDNHTDFDCRTNYRCVPMWSVCNGYDDCRDNSDEQGCEQRTCDPRGD--FRCDNHRCIPLRWKCDGDNDCNDGSDERNCS 3733 HSP 5 Score: 61.2326 bits (147), Expect = 9.379e-9 Identity = 38/121 (31.40%), Postives = 50/121 (41.32%), Query Frame = 3
Query: 1923 CPPGYRFCQNGE-CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C PGY C++ C+ CD N C D SDE P C ++ C + HW CD DC +G DE + C F C D + IP ++CD + DC DE
Sbjct: 2799 CQPGYTKCRSTNICIPRTYLCDGDNDCGDMSDESPTHC-----VTLTCTESEFRCSSGRCIPGHWYCDQGVDCSDGSDEPPTCVAHVRTCSSDQFRCDDARCIPASWICDGDNDCGDMSDE 2914 HSP 6 Score: 60.8474 bits (146), Expect = 1.395e-8 Identity = 39/115 (33.91%), Postives = 56/115 (48.70%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
N C+ C+ + C D SDE R CDP +C+ N++ +P + W CDG+ DC +G DE+NC S C F C + + IP ++CD + DC DE C
Sbjct: 3667 NYRCVPMWSVCNGYDDCRDNSDEQGCEQRTCDPRGDFRCD-NHRCIP------LRWKCDGDNDCNDGSDERNC---SPRECTESEFRCDNLRCIPGRWICDHDNDCEDNSDERDC 3771 HSP 7 Score: 59.6918 bits (143), Expect = 3.193e-8 Identity = 49/176 (27.84%), Postives = 64/176 (36.36%), Query Frame = 3
Query: 1881 EGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDP-----------ISR-------------------------------KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
+G ++ CP C NG C+ CD N C D SDE R CDP ISR KC N +P+ ++CDG+ DCG+ DE +L C F CS + IP + CD+ +DCS G DE
Sbjct: 2704 DGSDELERVCAFHTCPSTSFTCGNGRCVPYHYRCDHYNDCGDNSDELGCLFRTCDPNTEFTCNNGRCISRAYVCNGVNNCFDNGTSDERNCPDRTCQPGYTKCRSTNICIPRT------YLCDGDNDCGDMSDESPTHCVTL-TCTESEFRCSSGRCIPGHWYCDQGVDCSDGSDE 2872 HSP 8 Score: 58.9214 bits (141), Expect = 4.710e-8 Identity = 40/122 (32.79%), Postives = 57/122 (46.72%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C G C +G C + C+ C D SDED I C +CD +C N + +P+ W CD E+DCG+ DE + S C F C++ + IP+ + CD + DC DE
Sbjct: 3531 CRVGQFQCNDGNCTSSYFMCNSYPDCPDGSDEDQILCANHQCDTHQWQCA-NKRCIPES------WQCDQEDDCGDNSDEDSAH-CSTRTCNPGQFRCNNGRCIPQSWKCDVDDDCGDHSDE 3644 HSP 9 Score: 58.5362 bits (140), Expect = 5.672e-8 Identity = 42/120 (35.00%), Postives = 56/120 (46.67%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRE-CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
CQN C+ CD N C D SDE + C C+P +C + I P ++CDG++DC +G DE C NC F C S ++ I GY CD DC+ DE C +
Sbjct: 1096 CQNNRCIPRIWLCDTDNDCGDGSDE--LNCSNTCEPGQFQCPDHRCIDPS-------YVCDGDKDCVDGSDEMGC----TYNCSYSEFKCASGDQCISTGYQCDGVFDCNDHSDELNCPT 1202 HSP 10 Score: 58.5362 bits (140), Expect = 5.672e-8 Identity = 46/126 (36.51%), Postives = 60/126 (47.62%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLI--HWICDGEEDCGNGYDE--QNCDGFSLNNCGGKF-FTCSDNKTIPRGYVCDENIDCSQGEDET 2285
C PGY C +G C+ CD C D SDE R P C + + KN+ I +W CDG+ DCG+G DE Q+ D C F F C +N+ + R +C+ DCS G DET
Sbjct: 3776 CHPGYFQCNSGHCIAERFRCDGTADCLDVSDEAACPTRY--PNGTYCPAS--MFECKNHVCIQPYWRCDGDNDCGDGSDEELQHLD----IPCEPPFRFRCGNNRCVYRHEICNGVDDCSDGSDET 3893 HSP 11 Score: 57.7658 bits (138), Expect = 1.069e-7 Identity = 39/124 (31.45%), Postives = 56/124 (45.16%), Query Frame = 3
Query: 1926 PPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
P G C N C+ CD N C D SDE + REC +C+ N + +P + WICD + DC + DE++C+ + C +F C+ I + CD DC DE C +
Sbjct: 3699 PRGDFRCDNHRCIPLRWKCDGDNDCNDGSDERNCSPRECTESEFRCD-NLRCIPGR------WICDHDNDCEDNSDERDCE---IRTCHPGYFQCNSGHCIAERFRCDGTADCLDVSDEAACPT 3812 HSP 12 Score: 56.6102 bits (135), Expect = 2.551e-7 Identity = 42/129 (32.56%), Postives = 61/129 (47.29%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDED----PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE--QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
CP C+N C++ CD N C D SDE+ I C P +C NN+ + + H IC+G +DC +G DE + C + C + + C ++ +P YVCD+ DC DE GC
Sbjct: 3820 CPASMFECKNHVCIQPYWRCDGDNDCGDGSDEELQHLDIPCEP--PFRFRCG-NNRCVYR------HEICNGVDDCSDGSDETEEQCRPPTPRPCTDEEYKCGNHFCVPLHYVCDDYDDCGDHSDEAGC 3939 HSP 13 Score: 55.4546 bits (132), Expect = 6.089e-7 Identity = 40/123 (32.52%), Postives = 53/123 (43.09%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDED----PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C +G+C+ A CD++ C D +DE P+ C E S C +Q CDG DC + DE NC C F C + IPR ++CD + DC DE CT P
Sbjct: 98 CSSGQCIPRAYRCDRMKDCTDGADERNCLYPV-CTELSCGSGACYNRSQR------------CDGIVDCRDSSDESNC----TQRCLSSQFQCPSGECIPRDFLCDHDDDCGDESDEKNCTYP 203 HSP 14 Score: 52.7582 bits (125), Expect = 3.587e-6 Identity = 37/123 (30.08%), Postives = 54/123 (43.90%), Query Frame = 3
Query: 1944 CQNG-ECLENAKFCDKINHCADKSDEDPITCRE---CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C +G +C+ CD + C D SDE R C +C+ + +P +W CDG DC +G DE N + +C F C + I R ++CD + DC DE C +P
Sbjct: 1172 CASGDQCISTGYQCDGVFDCNDHSDELNCPTRPAGMCHQNEFQCQSDGACIPS------NWECDGHPDCIDGSDEHN--TCPVRSCPPSMFRCDNGNCIYRSWICDGDNDCRDMSDEKDCPTP 1286
BLAST of low density lipoprotein receptor-1 vs. Ensembl Xenopus
Match: rabggtb (Rab geranylgeranyltransferase subunit beta [Source:Xenbase;Acc:XB-GENE-953600]) HSP 1 Score: 77.411 bits (189), Expect = 1.153e-13 Identity = 69/243 (28.40%), Postives = 97/243 (39.92%), Query Frame = 3
Query: 1575 TEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC---RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
T PNG + P + + P +R+R Q+ + + G+ F N K + P + R G DN+ + C SS+ + C NG+C+ CD N C D+SDE R C S C+ NN+ +P+ W+CD + DCG+G DE NC N C F C D++ I YVCD + DC G DE GCT
Sbjct: 958 TNPNGDCSH---FCYPVPNLQRVCGCPYGMRLRPDQQTCFDDPASEPPTMQCGSYSFPCANGKCV------------PVYDRCD--GVDDCHDNSDEANCGTRNNTCSSRAFT----------CGNGQCIPLNWRCDSHNDCVDRSDEQNCPTQGPRSCSSTSFTCQ-NNRCIPRI------WLCDTDNDCGDGSDELNCS----NTCEPGQFQCPDHRCIDPSYVCDGDKDCVDGSDEMGCT 1162 HSP 2 Score: 63.1586 bits (152), Expect = 2.325e-9 Identity = 48/126 (38.10%), Postives = 58/126 (46.03%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C G C NG C+ + CD C D SDE R C +C + I W+CD EEDC +G DEQ+C G C + FTCS + IPR Y CD DC+ G DE C P
Sbjct: 13 CSSGSFRCSNGRCIPLSWRCDGTADCTDNSDEAGCPPRTCSTSQFRCGDGDCITSS-------WVCDDEEDCDDGSDEQHCPG---RTCSAQQFTCSSGQCIPRAYRCDRMKDCTDGADERNCLYP 128 HSP 3 Score: 62.3882 bits (150), Expect = 4.419e-9 Identity = 42/126 (33.33%), Postives = 66/126 (52.38%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLI-HW-ICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
C PG C NG C+ + CD + C D SDE P +EC + +C+ + + NY + W +C+G +DC + DEQ C+ + + G F C +++ IP + CD + DC+ G DE C+
Sbjct: 3562 CNPGQFRCNNGRCIPQSWKCDVDDDCGDHSDE-PF--QECMGPAYRCDNHTDFDCRTNYRCVPMWSVCNGYDDCRDNSDEQGCEQRTCDPRGD--FRCDNHRCIPLRWKCDGDNDCNDGSDERNCS 3682 HSP 4 Score: 61.2326 bits (147), Expect = 9.615e-9 Identity = 38/121 (31.40%), Postives = 50/121 (41.32%), Query Frame = 3
Query: 1923 CPPGYRFCQNGE-CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C PGY C++ C+ CD N C D SDE P C ++ C + HW CD DC +G DE + C F C D + IP ++CD + DC DE
Sbjct: 2794 CQPGYTKCRSTNICIPRTYLCDGDNDCGDMSDESPTHC-----VTLTCTESEFRCSSGRCIPGHWYCDQGVDCSDGSDEPPTCVAHVRTCSSDQFRCDDARCIPASWICDGDNDCGDMSDE 2909 HSP 5 Score: 60.8474 bits (146), Expect = 1.406e-8 Identity = 39/115 (33.91%), Postives = 56/115 (48.70%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
N C+ C+ + C D SDE R CDP +C+ N++ +P + W CDG+ DC +G DE+NC S C F C + + IP ++CD + DC DE C
Sbjct: 3616 NYRCVPMWSVCNGYDDCRDNSDEQGCEQRTCDPRGDFRCD-NHRCIP------LRWKCDGDNDCNDGSDERNC---SPRECTESEFRCDNLRCIPGRWICDHDNDCEDNSDERDC 3720 HSP 6 Score: 59.3066 bits (142), Expect = 3.219e-8 Identity = 49/176 (27.84%), Postives = 64/176 (36.36%), Query Frame = 3
Query: 1881 EGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDP-----------ISR-------------------------------KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
+G ++ CP C NG C+ CD N C D SDE R CDP ISR KC N +P+ ++CDG+ DCG+ DE +L C F CS + IP + CD+ +DCS G DE
Sbjct: 2699 DGSDELERVCAFHTCPSTSFTCGNGRCVPYHYRCDHYNDCGDNSDELGCLFRTCDPNTEFTCNNGRCISRAYVCNGVNNCFDNGTSDERNCPDRTCQPGYTKCRSTNICIPRT------YLCDGDNDCGDMSDESPTHCVTL-TCTESEFRCSSGRCIPGHWYCDQGVDCSDGSDE 2867 HSP 7 Score: 58.9214 bits (141), Expect = 4.589e-8 Identity = 40/122 (32.79%), Postives = 57/122 (46.72%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C G C +G C + C+ C D SDED I C +CD +C N + +P+ W CD E+DCG+ DE + S C F C++ + IP+ + CD + DC DE
Sbjct: 3480 CRVGQFQCNDGNCTSSYFMCNSYPDCPDGSDEDQILCANHQCDTHQWQCA-NKRCIPES------WQCDQEDDCGDNSDEDSAH-CSTRTCNPGQFRCNNGRCIPQSWKCDVDDDCGDHSDE 3593 HSP 8 Score: 58.9214 bits (141), Expect = 5.480e-8 Identity = 46/126 (36.51%), Postives = 60/126 (47.62%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLI--HWICDGEEDCGNGYDE--QNCDGFSLNNCGGKF-FTCSDNKTIPRGYVCDENIDCSQGEDET 2285
C PGY C +G C+ CD C D SDE R P C + + KN+ I +W CDG+ DCG+G DE Q+ D C F F C +N+ + R +C+ DCS G DET
Sbjct: 3725 CHPGYFQCNSGHCIAERFRCDGTADCLDVSDEAACPTRY--PNGTYCPAS--MFECKNHVCIQPYWRCDGDNDCGDGSDEELQHLD----IPCEPPFRFRCGNNRCVYRHEICNGVDDCSDGSDET 3842 HSP 9 Score: 58.5362 bits (140), Expect = 5.527e-8 Identity = 42/120 (35.00%), Postives = 56/120 (46.67%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRE-CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
CQN C+ CD N C D SDE + C C+P +C + I P ++CDG++DC +G DE C NC F C S ++ I GY CD DC+ DE C +
Sbjct: 1096 CQNNRCIPRIWLCDTDNDCGDGSDE--LNCSNTCEPGQFQCPDHRCIDPS-------YVCDGDKDCVDGSDEMGC----TYNCSYSEFKCASGDQCISTGYQCDGVFDCNDHSDELNCPT 1202 HSP 10 Score: 57.7658 bits (138), Expect = 1.024e-7 Identity = 39/124 (31.45%), Postives = 56/124 (45.16%), Query Frame = 3
Query: 1926 PPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
P G C N C+ CD N C D SDE + REC +C+ N + +P + WICD + DC + DE++C+ + C +F C+ I + CD DC DE C +
Sbjct: 3648 PRGDFRCDNHRCIPLRWKCDGDNDCNDGSDERNCSPRECTESEFRCD-NLRCIPGR------WICDHDNDCEDNSDERDCE---IRTCHPGYFQCNSGHCIAERFRCDGTADCLDVSDEAACPT 3761 HSP 11 Score: 56.6102 bits (135), Expect = 2.486e-7 Identity = 42/129 (32.56%), Postives = 61/129 (47.29%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDED----PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE--QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
CP C+N C++ CD N C D SDE+ I C P +C NN+ + + H IC+G +DC +G DE + C + C + + C ++ +P YVCD+ DC DE GC
Sbjct: 3769 CPASMFECKNHVCIQPYWRCDGDNDCGDGSDEELQHLDIPCEP--PFRFRCG-NNRCVYR------HEICNGVDDCSDGSDETEEQCRPPTPRPCTDEEYKCGNHFCVPLHYVCDDYDDCGDHSDEAGC 3888 HSP 12 Score: 55.4546 bits (132), Expect = 5.140e-7 Identity = 40/128 (31.25%), Postives = 57/128 (44.53%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC----RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGY-----VCDENIDCSQGEDETGCTSP 2300
C +G C+ +CD+ C+D SDE P TC R C +C+ + + +P WICDG+ DCG+ DE +C F C++ + + CD DC G DE GC P
Sbjct: 2843 CSSGRCIPGHWYCDQGVDCSDGSDEPP-TCVAHVRTCSSDQFRCD-DARCIPAS------WICDGDNDCGDMSDEDQ-----RRSCSSSEFACANGLCVRSNFRRGNSQCDRRNDCGDGSDERGCIYP 2957 HSP 13 Score: 55.4546 bits (132), Expect = 5.984e-7 Identity = 40/123 (32.52%), Postives = 53/123 (43.09%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDED----PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C +G+C+ A CD++ C D +DE P+ C E S C +Q CDG DC + DE NC C F C + IPR ++CD + DC DE CT P
Sbjct: 98 CSSGQCIPRAYRCDRMKDCTDGADERNCLYPV-CTELSCGSGACYNRSQR------------CDGIVDCRDSSDESNC----TQRCLSSQFQCPSGECIPRDFLCDHDDDCGDESDEKNCTYP 203 HSP 14 Score: 52.7582 bits (125), Expect = 3.646e-6 Identity = 37/123 (30.08%), Postives = 54/123 (43.90%), Query Frame = 3
Query: 1944 CQNG-ECLENAKFCDKINHCADKSDEDPITCRE---CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C +G +C+ CD + C D SDE R C +C+ + +P +W CDG DC +G DE N + +C F C + I R ++CD + DC DE C +P
Sbjct: 1172 CASGDQCISTGYQCDGVFDCNDHSDELNCPTRPAGMCHQNEFQCQSDGACIPS------NWECDGHPDCIDGSDEHN--TCPVRSCPPSMFRCDNGNCIYRSWICDGDNDCRDMSDEKDCPTP 1286
BLAST of low density lipoprotein receptor-1 vs. Ensembl Mouse
Match: Hspg2 (perlecan (heparan sulfate proteoglycan 2) [Source:MGI Symbol;Acc:MGI:96257]) HSP 1 Score: 130.183 bits (326), Expect = 4.883e-30 Identity = 78/216 (36.11%), Postives = 97/216 (44.91%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSF 2564
C P C +G C+ CD C D SDE + C P CE N + L W CDG+ DC + DE NC CG F C S N+ IP + CDE DC DE GC PQ+ + A++ Q VT TC ATG P P++ WR NWG I R + +L I+D K D G Y CEA++SR F
Sbjct: 285 CGPQEASCHSGHCIPRDYLCDGQEDCRDGSDE--LGCASPPP----CEPNEFACENGHCALKLWRCDGDFDCEDRTDEANCSVKQPGEVCGPTHFQCVSTNRCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPQQSIQASRGQTVTFTCVATGVPTPIINWRLNWGHIPAHPRVTMT-----SEGGRGTLIIRDVKEADQGAYTCEAMNSRGMVF 489 HSP 2 Score: 65.855 bits (159), Expect = 2.688e-10 Identity = 119/544 (21.88%), Postives = 212/544 (38.97%), Query Frame = 3
Query: 207 PPNITFFPLK--NDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANR----YLYIKSLLKQDEGIYNCSVEKVKDPQ-----IRFNRTLHLKITIPSISIDILPEES---LKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNL--KQSVSYKIK---IITNP--ALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIG-------NDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVS--MLVISDISQINEGNYECR----VGSSIKEVNLIVLLDEGLIETSPPILKVKE-------GQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNT 1715
P + F P++ S +E Q ++++C V A + W + G + A ++ L + + D G Y+C V + + I P ++ + E S L G + +C G + + L +++T G+ +L++ + + G Y+CQ + +EA+ + + Q+ S++++ I P + + G+ S +C + IK W +D+ + N + I + N G Y+CVAS + M +S+ + + + + GP V+V G+ L C SSG W G K L R+ G S ML I+ + + G Y C+ +G++ K+V LIV D G + P ++V+E G + HC P + W+ +R +P WQ I T +V+ + DSG YIC N +V+ + TI P + G V ++C + T
Sbjct: 2818 PGEVPFPPIRIETSSSRVAEGQTLDLSCVVPGQA--HAQVTWHKRGGSLPAGHQVHGHMLRLNRVSPADSGEYSCQVTGSSGTLEASVLVTIEASEPSPIPAPGLAQPVYIESSSSHLTEGQTVDLKCVVPGQAHAQVTWHKRGSSLPARHQTHGS--LLRLYQLSPADSGEYVCQVAGSSHPE-HEASFKLTVPSSQNSSFRLRSPVISIEPPSSTVQQGQDASFKCLIHEGATPIKVEWKIRDQELEDNVHISPNGSIITIVGTRPSNHGAYRCVAS------NVYGMAQSVVNLSVHGPPTVSVLPE-GP-VHVKMGKDITLEC---ISSGEPRSSPRWTRLGIPVK-----LEPRMFGLMNSHAMLKIASVKPSDAGTYVCQAQNALGTAQKQVELIV--DTGTVAPGAPQVQVEESELTLEAGHTATLHCSATGNPPP---TIHWS------KLRAPLP---WQ---HRIEGNT--LVIPRVAQQDSGQYICNATNSAGHTEATVVLHVESPPYATIIPEHTSAQPGNLVQLQCLAHGT 3321 HSP 3 Score: 60.077 bits (144), Expect = 1.676e-8 Identity = 72/278 (25.90%), Postives = 121/278 (43.53%), Query Frame = 3
Query: 903 LVIKSFKKDNVGTYKCVAS--LQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSI-KEVNLIVLLDEG----LIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYIC--TEPNGQT-ARSELIVIPDKDKNSLT--ITPREIRVRAGQRVDIEC 1700
L I++ + + GTY C S + G L S + + PQ+ V G++ E C +++GN EW I G +G +P ++ + +L + I ++G Y CR SS + V +L G ++ SP +V EG++V +CR +PS ++ W KEG ++P Q ++ T I + A +D+G+Y+C T P G AR +++V+ NS+ I V GQ +D+ C
Sbjct: 1824 LTIRNVQPSDAGTYVCTGSNMFAMDQGTATL------HVQVSGTSTAPVASIHPPQLTVQPGQQAEFRC---SATGNPTPMLEW-IGGP---SGQLPAKAQI---HNGILRLPAIEPSDQGQYLCRALSSAGQHVARAMLQVHGGSGPRVQVSPERTQVHEGRTVRLYCRAAGVPS---ASITWR---KEG---GSLPP---QARSENTDIPTLLIPAITA--ADAGFYLCVATSPTGTAQARIQVVVLSASGANSVPVRIESSSPSVTEGQTLDLNC 2071 HSP 4 Score: 53.1434 bits (126), Expect = 2.175e-6 Identity = 123/494 (24.90%), Postives = 180/494 (36.44%), Query Frame = 3
Query: 366 LYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEES---LKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTW-----YKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPG---------PQVYVHR-GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV----GSSIKEVNLIV-LLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPN--GQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG 1772
L I S+ D G Y C + + + T+ + + EES L+ G CS G P TI L Q++ GNT L IP V + G+YIC + S + AT V +S Y II + G L+C + Y W ++ + +Q L ++ ++ G Y+C S ++ S E Q S + T+ PG PQ+ G E HC + RG W G + G + DG +L I ++ Q +G Y C+ G + LIV L LI + V G SVEF C P + K + G+V++ S I + E++D+G Y C N G T L+++ + S TP EIRV AG C ASG P + T +K G
Sbjct: 3166 LKIASVKPSDAGTYVCQAQNALGTAQKQVELIVDTGTVAPGAPQVQVEESELTLEAGHTATLHCSATGNPPPTIHWSKLRAPLPWQHRIEGNT--LVIPRVAQQDSGQYIC---NATNSAGHTEATVVLHVESPPYA-TIIPEHTSAQPGNLVQLQCLAHG-TPPLTYQWSLVGGVLPEKAVARNQVLRLEPTVPEDSGRYRCQVSNRVGSA-----EAFAQVLVQGSSSNLPDTSIPGGSTPTVQVTPQLETRNIGASVEFHCAVPNE---RGTHLRWLKEGGQLPPGH----SVQDG----VLRIQNLDQSCQGTYVCQAHGPWGQAQATAQLIVQALPSVLINVRTSVHSVVVGHSVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG-----------------SIIRIAHVELADAGQYRCAATNAAGTTQSHVLLLVQALPQIS---TPPEIRVPAGSAAVFPCM-------ASGYPTPAITWSKVDG 3609
BLAST of low density lipoprotein receptor-1 vs. Ensembl Mouse
Match: Hspg2 (perlecan (heparan sulfate proteoglycan 2) [Source:MGI Symbol;Acc:MGI:96257]) HSP 1 Score: 130.183 bits (326), Expect = 4.923e-30 Identity = 78/216 (36.11%), Postives = 97/216 (44.91%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSF 2564
C P C +G C+ CD C D SDE + C P CE N + L W CDG+ DC + DE NC CG F C S N+ IP + CDE DC DE GC PQ+ + A++ Q VT TC ATG P P++ WR NWG I R + +L I+D K D G Y CEA++SR F
Sbjct: 285 CGPQEASCHSGHCIPRDYLCDGQEDCRDGSDE--LGCASPPP----CEPNEFACENGHCALKLWRCDGDFDCEDRTDEANCSVKQPGEVCGPTHFQCVSTNRCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPQQSIQASRGQTVTFTCVATGVPTPIINWRLNWGHIPAHPRVTMT-----SEGGRGTLIIRDVKEADQGAYTCEAMNSRGMVF 489 HSP 2 Score: 64.3142 bits (155), Expect = 9.156e-10 Identity = 115/526 (21.86%), Postives = 205/526 (38.97%), Query Frame = 3
Query: 255 SEMQFINIACNVTNYALNETSIRWLDKDGKVAAANR----YLYIKSLLKQDEGIYNCSVEKVKDPQ-----IRFNRTLHLKITIPSISIDILPEES---LKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNL--KQSVSYKIK---IITNP--ALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIG-------NDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVS--MLVISDISQINEGNYECR----VGSSIKEVNLIVLLDEGLIETSPPILKVKE-------GQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNT 1715
+E Q ++++C V A + W + G + A ++ L + + D G Y+C V + + I P ++ + E S L G + +C G + + L +++T G+ +L++ + + G Y+CQ + +EA+ + + Q+ S++++ I P + + G+ S +C + IK W +D+ + N + I + N G Y+CVAS + M +S+ + + + + GP V+V G+ L C SSG W G K L R+ G S ML I+ + + G Y C+ +G++ K+V LIV D G + P ++V+E G + HC P + W+ +R +P WQ I T +V+ + DSG YIC N +V+ + TI P + G V ++C + T
Sbjct: 2828 AEGQTLDLSCVVPGQA--HAQVTWHKRGGSLPAGHQVHGHMLRLNRVSPADSGEYSCQVTGSSGTLEASVLVTIEASEPSPIPAPGLAQPVYIESSSSHLTEGQTVDLKCVVPGQAHAQVTWHKRGSSLPARHQTHGS--LLRLYQLSPADSGEYVCQVAGSSHPE-HEASFKLTVPSSQNSSFRLRSPVISIEPPSSTVQQGQDASFKCLIHEGATPIKVEWKIRDQELEDNVHISPNGSIITIVGTRPSNHGAYRCVAS------NVYGMAQSVVNLSVHGPPTVSVLPE-GP-VHVKMGKDITLEC---ISSGEPRSSPRWTRLGIPVK-----LEPRMFGLMNSHAMLKIASVKPSDAGTYVCQAQNALGTAQKQVELIV--DTGTVAPGAPQVQVEESELTLEAGHTATLHCSATGNPPP---TIHWS------KLRAPLP---WQ---HRIEGNT--LVIPRVAQQDSGQYICNATNSAGHTEATVVLHVESPPYATIIPEHTSAQPGNLVQLQCLAHGT 3313 HSP 3 Score: 55.8398 bits (133), Expect = 3.568e-7 Identity = 70/276 (25.36%), Postives = 119/276 (43.12%), Query Frame = 3
Query: 903 LVIKSFKKDNVGTYKCVAS--LQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSI-KEVNLIVLLDEG----LIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYIC--TEPNGQT-ARSELIVIPDKDKNSLTITPREIRVRAGQRVDIEC 1700
L I++ + + GTY C S + G L S + + PQ+ V G++ E C +++GN EW I G +G +P ++ + +L + I ++G Y CR SS + V +L G ++ SP +V EG++V +CR +PS ++ W KEG ++P Q ++ T I + A +D+G+Y+C T P G AR +++V+ + I V GQ +D+ C
Sbjct: 1824 LTIRNVQPSDAGTYVCTGSNMFAMDQGTATL------HVQVSGTSTAPVASIHPPQLTVQPGQQAEFRC---SATGNPTPMLEW-IGGP---SGQLPAKAQI---HNGILRLPAIEPSDQGQYLCRALSSAGQHVARAMLQVHGGSGPRVQVSPERTQVHEGRTVRLYCRAAGVPS---ASITWR---KEG---GSLPP---QARSENTDIPTLLIPAITA--ADAGFYLCVATSPTGTAQARIQVVVL----SVPVRIESSSPSVTEGQTLDLNC 2065 HSP 4 Score: 53.1434 bits (126), Expect = 2.250e-6 Identity = 123/494 (24.90%), Postives = 180/494 (36.44%), Query Frame = 3
Query: 366 LYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEES---LKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTW-----YKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPG---------PQVYVHR-GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV----GSSIKEVNLIV-LLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPN--GQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG 1772
L I S+ D G Y C + + + T+ + + EES L+ G CS G P TI L Q++ GNT L IP V + G+YIC + S + AT V +S Y II + G L+C + Y W ++ + +Q L ++ ++ G Y+C S ++ S E Q S + T+ PG PQ+ G E HC + RG W G + G + DG +L I ++ Q +G Y C+ G + LIV L LI + V G SVEF C P + K + G+V++ S I + E++D+G Y C N G T L+++ + S TP EIRV AG C ASG P + T +K G
Sbjct: 3158 LKIASVKPSDAGTYVCQAQNALGTAQKQVELIVDTGTVAPGAPQVQVEESELTLEAGHTATLHCSATGNPPPTIHWSKLRAPLPWQHRIEGNT--LVIPRVAQQDSGQYIC---NATNSAGHTEATVVLHVESPPYA-TIIPEHTSAQPGNLVQLQCLAHG-TPPLTYQWSLVGGVLPEKAVARNQVLRLEPTVPEDSGRYRCQVSNRVGSA-----EAFAQVLVQGSSSNLPDTSIPGGSTPTVQVTPQLETRNIGASVEFHCAVPNE---RGTHLRWLKEGGQLPPGH----SVQDG----VLRIQNLDQSCQGTYVCQAHGPWGQAQATAQLIVQALPSVLINVRTSVHSVVVGHSVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG-----------------SIIRIAHVELADAGQYRCAATNAAGTTQSHVLLLVQALPQIS---TPPEIRVPAGSAAVFPCM-------ASGYPTPAITWSKVDG 3601
BLAST of low density lipoprotein receptor-1 vs. Ensembl Mouse
Match: Vldlr (very low density lipoprotein receptor [Source:MGI Symbol;Acc:MGI:98935]) HSP 1 Score: 78.1814 bits (191), Expect = 3.329e-14 Identity = 48/132 (36.36%), Postives = 60/132 (45.45%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNY--FLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
V C C+NG+C+ N CD C D SDE P C R C IN ++ + W CDGE DC NG DE+NC + C FTCS + + R +VC+ DC G DE C P
Sbjct: 68 VKKTCAESDFVCKNGQCVPNRWQCDGDPDCEDGSDESPEQCH-----MRTCRINEISCGARSTQCIPVSWRCDGENDCDNGEDEENCGNIT---CSADEFTCSSGRCVSRNFVCNGQDDCDDGSDELDCAPP 191 HSP 2 Score: 51.6026 bits (122), Expect = 5.100e-6 Identity = 45/137 (32.85%), Postives = 58/137 (42.34%), Query Frame = 3
Query: 1875 SLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNC-GGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
SLE Q + + CP C +GEC+ CD C D SDE R C P +CE + I + C+G DC +G DE NC ++N C G F C + I VCD+ DC DE
Sbjct: 225 SLE--QCGRQPVIHTKCPTSEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQ-------CNGIRDCVDGSDEVNCK--NVNQCLGPGKFKCRSGECIDMSKVCDQEQDCRDWSDE 350
BLAST of low density lipoprotein receptor-1 vs. Ensembl Mouse
Match: Vldlr (very low density lipoprotein receptor [Source:MGI Symbol;Acc:MGI:98935]) HSP 1 Score: 77.7962 bits (190), Expect = 4.077e-14 Identity = 48/132 (36.36%), Postives = 60/132 (45.45%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNY--FLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
V C C+NG+C+ N CD C D SDE P C R C IN ++ + W CDGE DC NG DE+NC + C FTCS + + R +VC+ DC G DE C P
Sbjct: 68 VKKTCAESDFVCKNGQCVPNRWQCDGDPDCEDGSDESPEQCH-----MRTCRINEISCGARSTQCIPVSWRCDGENDCDNGEDEENCGNIT---CSADEFTCSSGRCVSRNFVCNGQDDCDDGSDELDCAPP 191 HSP 2 Score: 51.2174 bits (121), Expect = 6.144e-6 Identity = 45/137 (32.85%), Postives = 58/137 (42.34%), Query Frame = 3
Query: 1875 SLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNC-GGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
SLE Q + + CP C +GEC+ CD C D SDE R C P +CE + I + C+G DC +G DE NC ++N C G F C + I VCD+ DC DE
Sbjct: 225 SLE--QCGRQPVIHTKCPTSEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQ-------CNGIRDCVDGSDEVNCK--NVNQCLGPGKFKCRSGECIDMSKVCDQEQDCRDWSDE 350
BLAST of low density lipoprotein receptor-1 vs. Ensembl Mouse
Match: Lrp1b (low density lipoprotein-related protein 1B [Source:MGI Symbol;Acc:MGI:2151136]) HSP 1 Score: 75.8702 bits (185), Expect = 2.346e-13 Identity = 45/118 (38.14%), Postives = 61/118 (51.69%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG+C++ CD I HC DKSDE + C R C + C N + +P +CDG DCG+ DE +C ++ C F C+D IPR C++N+DCS DE GC
Sbjct: 2404 CGNGDCVDYVLTCDGIPHCKDKSDEKLLYCENRSCRSGFKPC-YNRRCVPHGK------LCDGTNDCGDSSDELDC---KVSTCSTVEFRCADGTCIPRSARCNQNMDCSDASDEKGC 2511 HSP 2 Score: 64.6994 bits (156), Expect = 6.795e-10 Identity = 43/124 (34.68%), Postives = 59/124 (47.58%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGC 2291
C PG C G C A CD N C D SDE C KC N + +P ++ C+G++DCG+ DE++C N+C +F C K I + +VCDE+ DC+ DE C
Sbjct: 3243 CQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLAGQFKCTKNKKCIP------VNLRCNGQDDCGDEEDEKDC---PENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEANC 3357 HSP 3 Score: 64.3142 bits (155), Expect = 7.779e-10 Identity = 45/121 (37.19%), Postives = 58/121 (47.93%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINN--QILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C +G C+ CD N C D SDE I C + + S I N Q P N W CDGE+DC +G DE+ C+G L + KF S + I +VCD ++DC DE C S
Sbjct: 899 CSSGRCIPGHWACDGDNDCGDFSDETHINCTKEEARSPAGCIGNEFQCRPDGNCIPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCRSTGRCINNAWVCDGDVDCEDQSDEEDCDS 1019 HSP 4 Score: 61.6178 bits (148), Expect = 5.440e-9 Identity = 41/123 (33.33%), Postives = 53/123 (43.09%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQN--CDGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDE 2282
C Y C +G C+ N CD C D DE CD C N K HWICDGE+DCG+ DE + C + C F+C + +P+ ++CD DC G DE
Sbjct: 2568 CEENYFGCPSGRCILNTWVCDGQKDCEDGLDE-----LHCDS---SCSWNQFACSVKKCISKHWICDGEDDCGDSLDESDSICGAVT---CAADMFSCQGSHACVPQHWLCDGERDCPDGSDE 2679 HSP 5 Score: 60.8474 bits (146), Expect = 9.750e-9 Identity = 45/125 (36.00%), Postives = 62/125 (49.60%), Query Frame = 3
Query: 1920 ICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETG 2288
IC PG C+N C++ CD + C D SDED +TC C KC+ NN+ +PK+ W+CDG DCG+ DE N + C F+C + + IP ++CD DC DE
Sbjct: 730 ICKPGEFRCKNKHCIQARWKCDGDDDCLDGSDEDSVTCFNHSCPDDQFKCQ-NNRCIPKR------WLCDGANDCGSNEDESN-QTCTARTCQADQFSCGNGRCIPTAWLCDREDDCGDQTDEVA 846 HSP 6 Score: 60.077 bits (144), Expect = 1.807e-8 Identity = 47/131 (35.88%), Postives = 62/131 (47.33%), Query Frame = 3
Query: 1923 CPPGYRF-CQNGECLENAKFCDKINHCADKSDEDPITC-RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQ--NC---DGFSLNNCGGKFFTCS-DNKTIPRGYVCDENIDCSQGEDETGC 2291
C P +F C++G C+ N CD + C D+SDE + C C +C + + +P HW CDG+ DCG+ DE NC + S C G F C D IP + CD DC G DE GC
Sbjct: 853 CEPLTQFICKSGRCISNKWHCDTDDDCGDRSDE--VGCVHSCLDDQFRCS-SGRCIPG------HWACDGDNDCGDFSDETHINCTKEEARSPAGCIGNEFQCRPDGNCIPDLWRCDGEKDCEDGSDEKGC 974 HSP 7 Score: 59.3066 bits (142), Expect = 2.689e-8 Identity = 53/170 (31.18%), Postives = 71/170 (41.76%), Query Frame = 3
Query: 1791 ISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGC 2291
++N G +H L PG + + + + R S C C+ +C+ CD ++ C D SDE P C E C P +C LP +ICDGE DCG+ DE NCD + C F C+ NK IP C+ DC EDE C
Sbjct: 3165 VNNGGCSHLCLLGPGKTHTCACPTNFYLAADNRTCLSN------CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE-PDDCPEFKCQPGRFQCGTGLCALPA-------FICDGENDCGDNSDELNCD---THVCLAGQFKCTKNKKCIPVNLRCNGQDDCGDEEDEKDC 3317 HSP 8 Score: 58.9214 bits (141), Expect = 3.350e-8 Identity = 48/169 (28.40%), Postives = 63/169 (37.28%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCR--------------ECDPISRKCEIN--------------------NQILPKKNYF----------LIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C G++ C N C+ + K CD N C D SDE + C+ C P S +C N ++ K F L WICDG DCG+ DE C + + C +F C + I +VCD DC G DE C S
Sbjct: 2438 CRSGFKPCYNRRCVPHGKLCDGTNDCGDSSDE--LDCKVSTCSTVEFRCADGTCIPRSARCNQNMDCSDASDEKGCNNTDCTHFYKLGVKSTGFIRCNSTSLCVLPSWICDGSNDCGDYSDELKCPVQNKHKCEENYFGCPSGRCILNTWVCDGQKDCEDGLDELHCDS 2604
BLAST of low density lipoprotein receptor-1 vs. UniProt/SwissProt
Match: sp|Q05793|PGBM_MOUSE (Basement membrane-specific heparan sulfate proteoglycan core protein OS=Mus musculus OX=10090 GN=Hspg2 PE=1 SV=1) HSP 1 Score: 129.798 bits (325), Expect = 5.417e-29 Identity = 78/216 (36.11%), Postives = 97/216 (44.91%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSF 2564
C P C +G C+ CD C D SDE + C P CE N + L W CDG+ DC + DE NC CG F C S N+ IP + CDE DC DE GC PQ+ + A++ Q VT TC ATG P P++ WR NWG I R + +L I+D K D G Y CEA++SR F
Sbjct: 285 CGPQEASCHSGHCIPRDYLCDGQEDCRDGSDE--LGCASPPP----CEPNEFACENGHCALKLWRCDGDFDCEDRTDEANCSVKQPGEVCGPTHFQCVSTNRCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPQQSIQASRGQTVTFTCVATGVPTPIINWRLNWGHIPAHPRVTMT-----SEGGRGTLIIRDVKEADQGAYTCEAMNSRGMVF 489 HSP 2 Score: 57.3806 bits (137), Expect = 7.323e-7 Identity = 69/283 (24.38%), Postives = 113/283 (39.93%), Query Frame = 3
Query: 903 LVIKSFKKDNVGTYKCVAS--LQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSI-KEVNLIVLLDEG----LIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVI---PDKD-------KNSLTITPREIRVRAGQRVDIEC 1700
L I++ + + GTY C S + G L S + + PQ+ V G++ E C +++GN EW I G +G +P ++ + +L + I ++G Y CR SS + V +L G ++ SP +V EG++V +CR +PS ++ W E R+ SR +L + V+DSG Y+C N A+ I+I P + + I RV GQ +D+ C
Sbjct: 1824 LTIRNVQPSDAGTYVCTGSNMFAMDQGTATL------HVQVSGTSTAPVASIHPPQLTVQPGQQAEFRC---SATGNPTPMLEW-IGGP---SGQLPAKAQI---HNGILRLPAIEPSDQGQYLCRALSSAGQHVARAMLQVHGGSGPRVQVSPERTQVHEGRTVRLYCRAAGVPS---ASITWRKEGGSLPFRHQAHGSRLRLHH--------------MSVADSGEYVCRANNNIDAQETSIMISVSPSTNSPPAPASPAPIRIESSSSRVAEGQTLDLNC 2073
BLAST of low density lipoprotein receptor-1 vs. UniProt/SwissProt
Match: sp|P98160|PGBM_HUMAN (Basement membrane-specific heparan sulfate proteoglycan core protein OS=Homo sapiens OX=9606 GN=HSPG2 PE=1 SV=4) HSP 1 Score: 127.102 bits (318), Expect = 3.075e-28 Identity = 77/216 (35.65%), Postives = 97/216 (44.91%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSF 2564
C P C+NG C+ CD C D SDE +C P CE N + L W CDG+ DC + DE NC CG F C S N IP + CDE DC DE GC PQ+ + A++ Q VT TC A G P P++ WR NWG I + R + +L I+D K D G Y CEA+++R F
Sbjct: 285 CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDE-----LDCGP-PPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVT-----SEGGRGTLIIRDVKESDQGAYTCEAMNARGMVF 489
BLAST of low density lipoprotein receptor-1 vs. UniProt/SwissProt
Match: sp|Q06561|UNC52_CAEEL (Basement membrane proteoglycan OS=Caenorhabditis elegans OX=6239 GN=unc-52 PE=1 SV=2) HSP 1 Score: 100.523 bits (249), Expect = 4.250e-20 Identity = 100/334 (29.94%), Postives = 147/334 (44.01%), Query Frame = 3
Query: 1641 LTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG---------RDGRFKISNVGPAHKRLTAPGG-LSLSDNNMDVF--------CSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDED--PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTR---FSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
+T+ P E VR G+ V EC + R S N + +G GR I+ V +L+ G + +SD N + S ++VS+ + + C + C N EC++N CD C D+SDE P R C+P KC NN+ + K W+CDG++DCG+ DE NC+ S ++C F C D + +P + CD DC G DE GC P + T + + +LTC+A P P + WR NWG + R S + T LTI D + D G Y CEA++ + R +
Sbjct: 47 ITVFPSEKEVRDGRDVSFEC-----RARTSDNSVYPTVRWARVGGPLPSSAHDSGGRLTINPV-----QLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGLRQAGQCMADEKACGNNECVKNDYVCDGEPDCRDRSDEANCPAISRTCEPNEFKCN-NNKCVQKM------WLCDGDDDCGDNSDELNCNAKPSSSDCKPTEFQCHDRRQCVPSSFHCDGTNDCHDGSDEVGCVQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT--------LTIHDAQPVDQGAYTCEAINVKGRVLA 355
BLAST of low density lipoprotein receptor-1 vs. UniProt/SwissProt
Match: sp|P98156|VLDLR_MOUSE (Very low-density lipoprotein receptor OS=Mus musculus OX=10090 GN=Vldlr PE=1 SV=1) HSP 1 Score: 78.1814 bits (191), Expect = 2.328e-13 Identity = 48/132 (36.36%), Postives = 60/132 (45.45%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNY--FLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
V C C+NG+C+ N CD C D SDE P C R C IN ++ + W CDGE DC NG DE+NC + C FTCS + + R +VC+ DC G DE C P
Sbjct: 68 VKKTCAESDFVCKNGQCVPNRWQCDGDPDCEDGSDESPEQCH-----MRTCRINEISCGARSTQCIPVSWRCDGENDCDNGEDEENCGNIT---CSADEFTCSSGRCVSRNFVCNGQDDCDDGSDELDCAPP 191
BLAST of low density lipoprotein receptor-1 vs. UniProt/SwissProt
Match: sp|P98158|LRP2_RAT (Low-density lipoprotein receptor-related protein 2 OS=Rattus norvegicus OX=10116 GN=Lrp2 PE=1 SV=1) HSP 1 Score: 78.1814 bits (191), Expect = 3.497e-13 Identity = 47/122 (38.52%), Postives = 59/122 (48.36%), Query Frame = 3
Query: 1923 CPPGYRFCQNGE-CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINN-QILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
CPP + CQ C+ A CD N C D SDE+PI C S C N Q L + +W CDGE DC +G DE + G S+N C F C + + I +VCD + DC DE
Sbjct: 2823 CPPDFTKCQTTNICVPRAFLCDGDNDCGDGSDENPIYC-----ASHTCRSNEFQCLSPQRCIPSYWFCDGEADCADGSDEPDTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCGDMSDE 2939 HSP 2 Score: 72.7886 bits (177), Expect = 1.714e-11 Identity = 43/121 (35.54%), Postives = 63/121 (52.07%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDP--ITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C NG+C+ + CD ++ C D SDE + C P + C Q +P + W CD + DC +G DEQNC + ++ C FTC ++ IP+ +VCD + DCS G DE C +
Sbjct: 1032 CNNGKCVPSFFRCDGVDDCHDNSDEHQCGVFNNTCSPSAFACVRGGQCIPGQ------WHCDRQNDCLDGSDEQNCPTHATSSTCPSTSFTCDNHVCIPKDWVCDTDNDCSDGSDEKNCQA 1146 HSP 3 Score: 70.0922 bits (170), Expect = 8.844e-11 Identity = 39/124 (31.45%), Postives = 58/124 (46.77%), Query Frame = 3
Query: 1926 PPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
P G C N C+ CD + C D SDE+ REC +C + Q +P + W+CD E DCG+ DE++C+ + C + F C+ +P+ CD DC DE+ C +
Sbjct: 3723 PSGDFRCANHHCIPLRWKCDGTDDCGDNSDEENCVPRECSESEFRCA-DQQCIPSR------WVCDQENDCGDNSDERDCE---MKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPT 3836 HSP 4 Score: 70.0922 bits (170), Expect = 9.148e-11 Identity = 44/127 (34.65%), Postives = 61/127 (48.03%), Query Frame = 3
Query: 1926 PPGYRFCQNGECLENAKFCDKINHCADKSDED----PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
P + + G+C+ CD+ N C D SDE T C S C+ N+ +PK W+CD + DC +G DE+NC + C F C D++ I YVCD + DC+ G DE GC
Sbjct: 1068 PSAFACVRGGQCIPGQWHCDRQNDCLDGSDEQNCPTHATSSTCPSTSFTCD-NHVCIPKD------WVCDTDNDCSDGSDEKNCQ--ASGTCQPTQFRCPDHRCISPLYVCDGDKDCADGSDEAGCV 1185 HSP 5 Score: 68.5514 bits (166), Expect = 2.865e-10 Identity = 44/127 (34.65%), Postives = 56/127 (44.09%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C G C NG C+ + CD C D +DE R C+ C +P W+CD ++DC +G DE QNC G C + TCS+ + IP Y CD DC G DE C P
Sbjct: 28 CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGCPPRSCESGLFLCPAEGTCIPSS------WVCDEDKDCSDGADEQQNCAG---TTCSAQQMTCSNGQCIPSEYRCDHVSDCPDGSDERNCHYP 145 HSP 6 Score: 67.0106 bits (162), Expect = 9.517e-10 Identity = 42/133 (31.58%), Postives = 61/133 (45.86%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDED-------------PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C NG C+ CD N C D SDED TC P +R+C +P+ +W+CDG+ DC + DE QNC ++ C F+C++ + + + + CD DC DE GC+ P
Sbjct: 2915 CDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQNCSSTQFTCVNSRPPNRRC------IPQ------YWVCDGDADCSDALDELQNC---TMRTCSAGEFSCANGRCVRQSFRCDRRNDCGDYSDERGCSYP 3032 HSP 7 Score: 66.2402 bits (160), Expect = 1.663e-9 Identity = 49/149 (32.89%), Postives = 70/149 (46.98%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDE--------DPITCR--ECDPISRKC-----------EINNQILPKKNYF--------LIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C NG+C+ + CD ++ C D SDE D +TC C S++C E N L + F L ++CD + DC + DE+NC+ + CGG FTCS+ + I + +VCD + DC DE GC S Q
Sbjct: 115 CSNGQCIPSEYRCDHVSDCPDGSDERNCHYPTCDQLTCANGACYNTSQRCDQKVDCRDSSDEANCTTLCSQKEFECGSGECILRAYVCDHDNDCEDNSDERNCN---YDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDEDGCESNQ 260 HSP 8 Score: 65.855 bits (159), Expect = 1.794e-9 Identity = 46/130 (35.38%), Postives = 62/130 (47.69%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLI-HW-ICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
S C PG C NG C+ + CD N C D SDE PI EC + C+ + + K NY I W +C+G +DC + DEQ C+ + G F C+++ IP + CD DC DE C
Sbjct: 3633 ASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDE-PID--ECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGD--FRCANHHCIPLRWKCDGTDDCGDNSDEENCV 3757 HSP 9 Score: 60.4622 bits (145), Expect = 7.712e-8 Identity = 40/116 (34.48%), Postives = 56/116 (48.28%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDE 2282
C NG C+ + C+ IN+C D D C C P KC+ N +P+ ++CDG+ DCG+G DE N + + C F C S + IP + CD DC+ G DE
Sbjct: 2789 CSNGRCIPLSYVCNGINNCHDNDTSDEKNCPPHTCPPDFTKCQTTNICVPRA------FLCDGDNDCGDGSDE-NPIYCASHTCRSNEFQCLSPQRCIPSYWFCDGEADCADGSDE 2897 HSP 10 Score: 59.6918 bits (143), Expect = 1.516e-7 Identity = 43/131 (32.82%), Postives = 56/131 (42.75%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCR-ECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTS 2297
S CP C N C+ CD N C+D SDE C P +C + I P ++CDG++DC +G DE C + NC F C+D + I Y CD DC DE GC +
Sbjct: 1106 TSSTCPSTSFTCDNHVCIPKDWVCDTDNDCSDGSDEKNCQASGTCQPTQFRCPDHRCISPL-------YVCDGDKDCADGSDEAGC----VLNCTSAQFKCADGSSCINSRYRCDGVYDCRDNSDEAGCPT 1225 HSP 11 Score: 59.3066 bits (142), Expect = 2.090e-7 Identity = 41/126 (32.54%), Postives = 60/126 (47.62%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLI-HWICDGEEDCGNGYDE--QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
CP C+N C+++ CD N C D SDE+ C + CE + + + H +C+G +DCG+G DE ++C + C + CS+ I + YVCD DC DETGC
Sbjct: 3844 CPAAMFECKNHVCIQSFWICDGENDCVDGSDEEIHLC-----FNIPCESPQRFRCDNSRCVYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCISQHYVCDNVNDCGDLSDETGC 3964 HSP 12 Score: 58.9214 bits (141), Expect = 2.785e-7 Identity = 44/123 (35.77%), Postives = 57/123 (46.34%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE--QNCDGFSLNNCGGKFFTCSDN-KTIPRGYVCDENIDCSQGEDETGCTS 2297
C N C+ + CD +N C D SDED C R C P KC N + +P+ W CD + DCG+ DE C + N F+C N + IP+ VC+ DC DE GC S
Sbjct: 3603 CANKRCIPQSWQCDSVNDCLDNSDEDTSHCASRTCRPGQFKCN-NGRCIPQS------WKCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCES 3718 HSP 13 Score: 57.7658 bits (138), Expect = 5.293e-7 Identity = 41/124 (33.06%), Postives = 56/124 (45.16%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLN-NCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C G C NG C+ + CD+ N C D SDE + C C+ N + +P+ ++CD + DCG+G DEQ + C F C + I G VC+ DCS DE GC
Sbjct: 2995 CSAGEFSCANGRCVRQSFRCDRRNDCGDYSDERGCSYPPCHANQFTCQ-NGRCIPR------FFVCDEDNDCGDGSDEQEHLCHTPEPTCPLHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKGC 3111 HSP 14 Score: 54.6842 bits (130), Expect = 4.561e-6 Identity = 40/129 (31.01%), Postives = 54/129 (41.86%), Query Frame = 3
Query: 1917 DICPPGYRFCQ-------NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
D+CP +RFC+ +G C C+ CAD SDED + C +CE N K W CD DC + DE S C F C++ + IP+ + CD + DC DE
Sbjct: 3548 DLCP--HRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVLCEH-----HRCESNEWQCANKRCIPQSWQCDSVNDCLDNSDEDTSHCAS-RTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDE 3668
BLAST of low density lipoprotein receptor-1 vs. TrEMBL
Match: A0A1Z1R275 (Low density lipoprotein receptor-related 1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1665.97 bits (4313), Expect = 0.000e+0 Identity = 822/823 (99.88%), Postives = 823/823 (100.00%), Query Frame = 3
Query: 129 CIYQSLVKAETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 2597
CIYQSLVKAETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQ+LPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN
Sbjct: 1 CIYQSLVKAETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQVLPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 823
BLAST of low density lipoprotein receptor-1 vs. TrEMBL
Match: T1DBM0 (LDL-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 946.806 bits (2446), Expect = 0.000e+0 Identity = 459/815 (56.32%), Postives = 594/815 (72.88%), Query Frame = 3
Query: 162 EEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQ---SVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGK-LDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKN 2594
+EFTFGGA++EEE + F +KNDSIVKSEM+++ + CNVTN N + RWLDK+G V + N+ LY KSLLK EGIY C VEK ++ N+T L ITIPSISI++LP+ESL+IGGQI R CSD +I D ++ W++++NKT+ N+N L IP+ DESV G Y C+ KS TSK+Y A T VN+++ S +YKI+I T P + + F+L C+V P I+Y W K + I ++ + I SFKK+N+G YKC+A ++L +G L L ES+QQ FR SK+EL PG + VH GEKKELHCEIE + RG E EWYIN F+ GD + RLD + VSMLVI +I NEG YECR KE+N++VL ++G+I+T+PP+L+VKEGQSVEFHCRV+N +VKNV+LKW F SK+G V +IP+ RW+ N +I ++TSF+ L A ++D+GY ICTEPNGQ+A+SELIV + N +TITP+EIRVR QR DIECF+K +GRASG P+F F+NNK +GRD RF + VG +H RL+AP GL LS++NMDVFC ++VSSKIY+ D CPPG+R+CQNG+CLENAKFCD C DKSDEDP C+ CDPIS+KCE++ I+P KNY+L+HW CDGEEDCGNGYDE+NC L NCGGKFF CSD K IPRGY+CD+N DC G+DE CT P I KTS ++ A ++Q VT+TCEA+GKPLP +VWRFNWGCIQ RFS +S++C +V+S+LTI +F+ GDDGIYNCEALSSRQR+FS+DFQV+L+N
Sbjct: 21 DEFTFGGAADEEEDEA--VINFNMKNDSIVKSEMEYLYVLCNVTNLKPNTFTARWLDKNGVVVSPNKILYFKSLLKHREGIYKCEVEK---DSVKSNKTFQLNITIPSISINVLPDESLQIGGQISRNCSDFKSMNLSITDTLSHEWVDEKNKTVSNSNFLVIPIKDESVSGTYECRLKSFATSKVYTAKTMVNVQRKVVSANYKIQISTTPGTITFAKMFTLNCDVTP-SNGIQYRWLKDNIEISTNKTIYIPSFKKENIGVYKCIAIVKLENGNNLTLEAESLQQLTLFRHSKVELDETPGYTIIVHSGEKKELHCEIEVEAKKRGVEVEWYINNTLFRRGDFRNIGRLDKELVSMLVIRNIVAQNEGKYECRYADKRKEINIVVLTEQGIIQTNPPLLRVKEGQSVEFHCRVDNFANVKNVDLKWKFRSKDGSVTYDIPNDRWETTNPDITEETSFLELNSAVMADNGYLICTEPNGQSAQSELIVTAG-EGNVITITPKEIRVRPHQRFDIECFTKTREGRASGQPKFFFSNNKAVGRDARFVETTVGQSHIRLSAPNGLPLSEDNMDVFCGSGDQRVSSKIYIKDTCPPGHRYCQNGQCLENAKFCDGKVDCEDKSDEDPNLCKACDPISKKCEVHRGIIPTKNYYLVHWACDGEEDCGNGYDEENCGEGYLENCGGKFFKCSDGKNIPRGYLCDQNADCDNGDDENLCTYPTIIKTSTKEIKAARTQQVTMTCEASGKPLPAIVWRFNWGCIQQLPRFSVRSYSSNCTTVSSTLTINNFQPGDDGIYNCEALSSRQRAFSDDFQVVLQN 828
BLAST of low density lipoprotein receptor-1 vs. TrEMBL
Match: I1ZIB9 (Low density lipoprotein receptor-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 720.694 bits (1859), Expect = 0.000e+0 Identity = 361/363 (99.45%), Postives = 361/363 (99.45%), Query Frame = 3
Query: 1509 ADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 2597
ADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSL GRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCN VTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN
Sbjct: 1 ADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLXGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNFVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 363
BLAST of low density lipoprotein receptor-1 vs. TrEMBL
Match: A0A183A6H7 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS2562 PE=4 SV=1) HSP 1 Score: 442.965 bits (1138), Expect = 1.801e-138 Identity = 263/801 (32.83%), Postives = 409/801 (51.06%), Query Frame = 3
Query: 306 NETSIRWL----DKDGKVAAANRYLYIKSLLKQD-EGIYNCSVEKVKDPQIRFNRTLHLKI-----TIPS---ISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYV---NLKQSVSYKIKIITNPALFRYGERFSLRCEVEPF-YQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQ---QFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVN------RLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNI---PDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPN-GQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGR-ASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEG--RQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDN-KTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCI-QNSTRFSTNFFSTDCN----SVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILK 2591
+E S +W+ D + ++ LY+ + +D + C V ++ D Q+ F + L++++ ++P+ ++I LP E L G+I RQC L E I F + WL+Q + + N + L + + D + +G Y C+ + +S IY+A +V + Q+ Y + I+ + G + + C VEP + + + WY KD +G+D L + S ++G+Y C A + M + A +E++IE++ PG + GE +ELHCE S +W+ G+ + P +N R+D VS++ + + + G YECRV IK+ ++IV +++GL E +P V EG VEFHCR N ++W ++ G + P++ + + A TSFI ++A SD G YIC P+ G AR L V + + ITP ++VR +++EC+ GR A P FS +++ RF+ V R GL N V CS++G R +S I + D CP G+R C++G+CL +FCD + CAD SDEDP C EC+P RKCE P K+ ++HWICDGE+DCGNG+DE NC CG FTC ++ + IPR +VCD++ DC GEDE C P I + + V LTC TG PLP ++WRFNWGC+ +N R+ + +C+ SV S+LTI + + GDDGIYNCE L+ R+ SND+ V+++
Sbjct: 69 HEYSFKWIRRLPDHSSQEVSSTAVLYLSDVRVEDMQHPLYCQVTRLSDGQV-FEKVLNIRMVGYGGSLPAELTLTIRSLPAEDLS-AGRIMRQC--LFENNEEINQQFDFRWLDQNGRVVTNGDALYLMLEDPADLGNYTCEATHRSSSNIYQAKYHVTRSSRAQASQYIVTIVPDTTQVLLGRPYEMLCRVEPMPSEPVSFRWYHKDRMVGSDARLRLPSLTYPDLGSYVCRAEWTPAYSRTGSMAANATVDLSLALTKEAEIEMSPPPGSVLVTLPGETRELHCEYGQLSN---PSVQWFFEGQPLERH--PTLNASSRVYRMDRLRVSIITLRGVEVGHGGTYECRVNGQIKQTHVIVRVEDGL-EVNPSEDTVDEGTPVEFHCRAHGADRNVNQEMQWFYQPFSGGPVEPVNLHPETGFVRQDHPYASHTSFISRLRARKSDEGIYICRLPSQGAEARGRLYVRATV-QYRVVITPSVVKVRVNNPIEMECYVMEDTGRPADVLPTFSLMDSRI-----RFEQERVAANRVRFIIRSGLGAEYNGTQVRCSVDGTDRFATSTIVIEDTCPHGFRRCRSGDCLPAGRFCDGVRDCADGSDEDPRLCNECEPTVRKCEYYQNRAPLKSTHMVHWICDGEDDCGNGFDEANCPDPLFAQCGDYMFTCPNSQRRIPRSFVCDKDQDCEYGEDERNCAGPTIESSGNYRHSVRAGTQVVLTCRVTGHPLPRVIWRFNWGCLPENDNRYRVTSVAQNCDSPMPSVVSTLTISNVRPGDDGIYNCEGLAGSMRAMSNDYFVMIE 853
BLAST of low density lipoprotein receptor-1 vs. TrEMBL
Match: A0A4E0RPR1 (Basement membrane-specific heparan sulfate proteoglycan core protein OS=Fasciola hepatica OX=6192 GN=D915_000102 PE=4 SV=1) HSP 1 Score: 426.787 bits (1096), Expect = 2.268e-132 Identity = 268/848 (31.60%), Postives = 422/848 (49.76%), Query Frame = 3
Query: 162 EEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWL----DKDGKVAAANRYLYIKSLLKQD-EGIYNCSVEKVKDPQIRFNRTLHLKI------TIPS---ISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYV---NLKQSVSYKIKIITNPA-LFRYGERFSLRCEVEPF-YQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVN------RLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNI---PDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPN-GQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGR-ASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEG--RQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDN-KTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCI-QNSTRFSTNFFSTDCN----SVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILK 2591
E+ + G +++E P IT P + + + + C V+N +E S++W+ D + ++ LYI ++ + C ++ D Q F + L++++ ++P+ ++I LP E L G +I RQC G E + + F + WL+Q + + N + L + + D + +G Y C+ + ++ IY+A +V + Q+ Y + ++ + A G + + C VEP + + Y WY D +G+D L + S ++G Y C A A+ R K ++ PG + GE +ELHCE S +W+ G+ + P +N R+D VS++ +S + + G YECR+ IK+ ++IV +++GL E +P V EG VEFHCR N ++W ++ G + P++ + + A TSFI ++A SD G YIC P+ G AR L V + + ITP ++VR ++ EC+ GR A P FS +++ RF V R GL+ N V C++EG R +S I + D CP G+R C++G+CL +FCD C D SDEDP C EC+P +KCE P K+ ++IHW+CDGE+DCGNG+DE NC S+ CG FTC ++ + IPR +VCD++ DC GEDE C P I + + V LTC TG PLP ++WRFNWGC+ +N R+ + +C+ SV S+LTI + + GDDGIYNCE LS R+ SND+ V+++
Sbjct: 26 EDISLAGYHQDDE---PEITLMPGDPGPLEVNLGEQVYSRCTVSNS--HEYSVKWIRRLPDHSTQEVSSTAMLYIPEARAEEMQHPLYCQATRLSDGQT-FEKALNIRMVGYGGASLPADLTLTIRSLPAEDLSTG-RIMRQCLFEG--NEEVNEQFDFRWLDQNGRVVTNGDALYLMLEDPADLGNYTCEATHRSSNNIYQAKYHVTRPSHAQASQYVVTVVPDAASQVLLGRPYEMLCRVEPMPSEPVTYRWYHNDRMVGSDARLRLPSLAYPDIGNYVCRAEWTP---------------AYSRSGK--MSPPPGSVLVTLPGETRELHCEFGQLSS---PSVQWFFEGQPLERH--PTLNASRRVYRMDRLRVSIVTLSGVEVGHGGTYECRINGQIKQTHVIVRVEDGL-EVNPSEDTVDEGTPVEFHCRAHGADQNVNREMQWFYQPFSGGPIQPVDLNPETGFVRQDHPYASHTSFISRLRARKSDEGIYICRLPSEGSEARGRLYVR-STVQYRVVITPPVLKVRVNNPIEFECYVVEDTGRQADVLPNFSVLDSR-----IRFDQERVAANRVRFLIRSGLTSEYNGTQVRCAVEGTDRYATSTIVIEDTCPHGFRRCRSGDCLPAGRFCDGRRDCPDGSDEDPRLCNECEPTVKKCEYYQNRPPLKSTYMIHWMCDGEDDCGNGFDEANCPDPSIAQCGDYMFTCPNSQRRIPRSFVCDKDQDCEYGEDERNCVGPTIESIADYRHSVRAGTQVILTCRVTGNPLPRVIWRFNWGCLPENDNRYRITNVAQNCDSPMPSVISTLTISNVRPGDDGIYNCEGLSGSMRAMSNDYFVMIE 835
BLAST of low density lipoprotein receptor-1 vs. Ensembl Cavefish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 128.642 bits (322), Expect = 1.114e-29 Identity = 80/228 (35.09%), Postives = 108/228 (47.37%), Query Frame = 3
Query: 1941 FCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN*STEFYY 2618
CQNG+C+ CD C D SDE + C P CE N L W CDG+ DC + DE +C + C + F C SD IP Y CDE DC+ DE GC P +T V A + VT TC+A G P P++ WR NWG I S+R + + +LTI+D K GD G Y CEA++++ F+ V+ N + F++
Sbjct: 197 MCQNGQCISRDYLCDGERDCTDGSDE--MKCGTPSP----CEPNEFKCKNGRCALKLWRCDGDNDCKDNSDEMDCPVRRPGDACAPEQFVCLSDRACIPASYQCDEEPDCADRSDEYGCAPPTVTSPPEDSVTAMRGGTVTFTCKAVGVPTPIITWRLNWGHIPVSSRITMTS-----ENGQGTLTIRDVKEGDQGAYTCEAINAKGLVFAIPDGVLTLNRNAGPFFF 413 HSP 2 Score: 78.9518 bits (193), Expect = 1.919e-14 Identity = 113/498 (22.69%), Postives = 196/498 (39.36%), Query Frame = 3
Query: 357 NRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLK-------ITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPV-----VDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSY---KIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVH-------RGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV--GSSIKEVNLIVL-------LDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPR-EIRVRAGQRVDIECFSKNTQGRASGNPEFSFT 1754
N L I+++ +D G+Y C+ + + LH++ I +P +I P +++ G + + +C+ G P + W K I + +++ V VD S G YIC+ + A YV+ SV Y +++ GE L C + TW K+ E + L + + K+ + GTY CV + + S E++IE+T G V + GE +L+C + GN W NG + +++ G + L I SQ + G Y CRV G +++ ++ V L +I P VK G+ F CRV + + V L+W + + IPD N +I+ S I + A+ + G Y C N ++ + ++ T+TP + V+ G +++EC +A+G P S +
Sbjct: 1674 NGILTIQNVQPEDYGVYVCTGSNMFG-MDESSAVLHVQGSSLIKTIQLPVATIQP-PVLTIQQGQRAEFRCTASGNPAPAV------EWTGGPGKRISSNAVIRGGVLTFTSVDRSDEGDYICRALNTHGEHTARAVLYVH-STSVPYLLPHVQVSPQQVELHEGETLRLYCRAG-GTPSPGLTWKKRVERT-DFGTLTVPNMKRSDGGTYLCVGTNAVGS----------------SEARIEVTVVKGNDVSIQPSEASVVEGETLDLNCFV---PGNPPPSVTW-----SRANGYLSPNHQVIG---TQLRILRASQEDSGEYICRVDGGPHVRQASVSVSVTSESSRLQSPIISIEPHSAAVKLGEPASFRCRVHS--GAQPVRLEWKLTNNQ-----PIPD------NAKISPDGSVITITNAQSKNKGTYRCVASNPFGITQSIVSLIVRESPRATVTPTGPVHVKVGDPINLEC-------QAAGEPRPSVS 2113 HSP 3 Score: 77.411 bits (189), Expect = 5.674e-14 Identity = 115/526 (21.86%), Postives = 190/526 (36.12%), Query Frame = 3
Query: 270 INIACNVTNYALNETSIRWLDKDGKVAAA-------NRYLYIKSLLKQDEGIYNCSVEKVKDP-QIRFNRTLHLKITIPSISIDILPEESLKI---GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEE-SIQQFAFFRESKIELTTKPGPQVYVHR-GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRL-DGQYVSMLVISDISQINEGNYECRVGSSIKEVN-----LIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQT----SFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNK 1763
IN+ C S LD K + N L I +D G Y C+ + + + R + +P++ + E +K+ G C G P+ TI L ++K + + +L P V G+YIC T+ + + + L + ++ + R GE L+C +++ W K + E L I D+ GTYKCVAS ++ G + M + S++ L+ + PQV V G E C +++G + EW G G +P + + DG +L I ++ + NEG Y CR SS + I L + +I + V G SVEF C+ P P RW + ++ D + +++ +D+G Y CT N + +V+ + + P V G C ASG P + T +K
Sbjct: 2098 INLECQAAGEPRPSVSWHRLDNARKTMLSSPVPMESNAVLQILVARAEDSGTYVCTAQNNQGTTETRIEVIVEGGPAVPTVPRASV-REPMKVVVEGSTTTLHCDGYGFPKPTISWSKLRAPLPWRHKIVNGSLVL--PSVGRQDSGQYICNV----TNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAH-GTPPLRFEWSKVGGVLPATAEQQGGDLQINLASPDDAGTYKCVASNKV--GHSEAMAKVSVRLICNRVVCSAPLSVRVSPQVDVKALGSAAEFTC---SANGGPDIKLEWLKEG-----GALPPNHHVRDG----VLRIENLEKSNEGVYICRATSSYGQAQDSARLTIQALPKVMINVRTSVQTVMVGNSVEFECQAVGEPK---------------------PTIRWSKVGGKLPDHVQVKGGMLRIIQVTEADAGQYRCTATNDVGSVQSTVVLSIQSLPQIATQPETKEVTVGSNAVFPCI-------ASGYPVPTITWSK 2573 HSP 4 Score: 71.2478 bits (173), Expect = 4.873e-12 Identity = 106/477 (22.22%), Postives = 186/477 (38.99%), Query Frame = 3
Query: 366 LYIKSLLKQDEGIYNC-SVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQ-----YKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTW-------YKKDEFIGNDQELV-IKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYI--NGKK-FKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV--GSSIKEVNLIVLLDEG-LIETSP------PILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNT 1715
L + ++ + D G Y C V + R T+ + + I P E+ + G+ + C G P ++ +L+ ++ IG L+I + G YIC+ + + + + + L+ + I I + A + GE S RC V Q ++ W + I D ++ I + + N GTY+CVAS P G + +SI RES T GP V+V G+ L C+ ++G W+ N +K + +P+ + ++L I + G Y C E + V+++ G + T P P+ V EG + HC P + W+ +R +P R +++N + VL DSG YIC N I++ + T+ P ++ VR G+ + ++C + T
Sbjct: 1860 LTVPNMKRSDGGTYLCVGTNAVGSSEARIEVTV-----VKGNDVSIQPSEASVVEGETLDLNCFVPGNPPPSVTWSRANGYLSPNHQVIGTQ--LRILRASQEDSGEYICRVDGGPHVRQASVSVSVTSESSRLQSPI---ISIEPHSAAVKLGEPASFRCRVHSGAQPVRLEWKLTNNQPIPDNAKISPDGSVITITNAQSKNKGTYRCVASN--PFG----ITQSIVSL-IVRESPRATVTPTGP-VHVKVGDPINLECQ---AAGEPRPSVSWHRLDNARKTMLSSPVPMESN------AVLQILVARAEDSGTYVCTAQNNQGTTETRIEVIVEGGPAVPTVPRASVREPMKVVVEGSTTTLHCDGYGFP---KPTISWS------KLRAPLP-WRHKIVNGSL-------VLPSVGRQDSGQYICNVTNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAHGT 2292
BLAST of low density lipoprotein receptor-1 vs. Ensembl Cavefish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 128.257 bits (321), Expect = 1.404e-29 Identity = 80/228 (35.09%), Postives = 108/228 (47.37%), Query Frame = 3
Query: 1941 FCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN*STEFYY 2618
CQNG+C+ CD C D SDE + C P CE N L W CDG+ DC + DE +C + C + F C SD IP Y CDE DC+ DE GC P +T V A + VT TC+A G P P++ WR NWG I S+R + + +LTI+D K GD G Y CEA++++ F+ V+ N + F++
Sbjct: 197 MCQNGQCISRDYLCDGERDCTDGSDE--MKCGTPSP----CEPNEFKCKNGRCALKLWRCDGDNDCKDNSDEMDCPVRRPGDACAPEQFVCLSDRACIPASYQCDEEPDCADRSDEYGCAPPTVTSPPEDSVTAMRGGTVTFTCKAVGVPTPIITWRLNWGHIPVSSRITMTS-----ENGQGTLTIRDVKEGDQGAYTCEAINAKGLVFAIPDGVLTLNRNAGPFFF 413 HSP 2 Score: 80.4925 bits (197), Expect = 7.433e-15 Identity = 111/491 (22.61%), Postives = 193/491 (39.31%), Query Frame = 3
Query: 357 NRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPV-----VDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSY---KIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVH-------RGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV--GSSIKEVNLIVL-------LDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPR-EIRVRAGQRVDIECFSKNTQGRASGNPEFSFT 1754
N L I+++ +D G+Y C+ + + LH + +I +L +++ G + + +C+ G P + W K I + +++ V VD S G YIC+ + A YV+ SV Y +++ GE L C + TW K+ E + L + + K+ + GTY CV + + S E++IE+T G V + GE +L+C + GN W NG + +++ G + L I SQ + G Y CRV G +++ ++ V L +I P VK G+ F CRV + + V L+W + + IPD N +I+ S I + A+ + G Y C N ++ + ++ T+TP + V+ G +++EC +A+G P S +
Sbjct: 1687 NGILTIQNVQPEDYGVYVCTGSNMFG-MDESSAVLHGSQPVATIQPPVL---TIQQGQRAEFRCTASGNPAPAV------EWTGGPGKRISSNAVIRGGVLTFTSVDRSDEGDYICRALNTHGEHTARAVLYVH-STSVPYLLPHVQVSPQQVELHEGETLRLYCRAG-GTPSPGLTWKKRVERT-DFGTLTVPNMKRSDGGTYLCVGTNAVGS----------------SEARIEVTVVKGNDVSIQPSEASVVEGETLDLNCFV---PGNPPPSVTW-----SRANGYLSPNHQVIG---TQLRILRASQEDSGEYICRVDGGPHVRQASVSVSVTSESSRLQSPIISIEPHSAAVKLGEPASFRCRVHS--GAQPVRLEWKLTNNQ-----PIPD------NAKISPDGSVITITNAQSKNKGTYRCVASNPFGITQSIVSLIVRESPRATVTPTGPVHVKVGDPINLEC-------QAAGEPRPSVS 2117 HSP 3 Score: 77.411 bits (189), Expect = 6.073e-14 Identity = 116/532 (21.80%), Postives = 192/532 (36.09%), Query Frame = 3
Query: 270 INIACNVTNYALNETSIRWLDKDGKVAAA-------NRYLYIKSLLKQDEGIYNCSVEKVKDP-QIRFNRTLHLKITIPSISIDILPEESLKI---GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEE---SIQQFAFFRESKI----ELTTKPGPQVYVHR-GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRL-DGQYVSMLVISDISQINEGNYECRVGSSIKEVN-----LIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQT----SFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNK 1763
IN+ C S LD K + N L I +D G Y C+ + + + R + +P++ + E +K+ G C G P+ TI L ++K + + +L P V G+YIC T+ + + + L + ++ + R GE L+C +++ W K + E L I D+ GTYKCVAS ++ G + M + F F +++ L+ + PQV V G E C +++G + EW G G +P + + DG +L I ++ + NEG Y CR SS + I L + +I + V G SVEF C+ P P RW + ++ D + +++ +D+G Y CT N + +V+ + + P V G C ASG P + T +K
Sbjct: 2102 INLECQAAGEPRPSVSWHRLDNARKTMLSSPVPMESNAVLQILVARAEDSGTYVCTAQNNQGTTETRIEVIVEGGPAVPTVPRASV-REPMKVVVEGSTTTLHCDGYGFPKPTISWSKLRAPLPWRHKIVNGSLVL--PSVGRQDSGQYICNV----TNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAH-GTPPLRFEWSKVGGVLPATAEQQGGDLQINLASPDDAGTYKCVASNKV--GHSEAMAKVSVRCDTFTFLICNRVVCSAPLSVRVSPQVDVKALGSAAEFTC---SANGGPDIKLEWLKEG-----GALPPNHHVRDG----VLRIENLEKSNEGVYICRATSSYGQAQDSARLTIQALPKVMINVRTSVQTVMVGNSVEFECQAVGEPK---------------------PTIRWSKVGGKLPDHVQVKGGMLRIIQVTEADAGQYRCTATNDVGSVQSTVVLSIQSLPQIATQPETKEVTVGSNAVFPCI-------ASGYPVPTITWSK 2583 HSP 4 Score: 71.2478 bits (173), Expect = 4.874e-12 Identity = 106/477 (22.22%), Postives = 186/477 (38.99%), Query Frame = 3
Query: 366 LYIKSLLKQDEGIYNC-SVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQ-----YKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTW-------YKKDEFIGNDQELV-IKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYI--NGKK-FKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV--GSSIKEVNLIVLLDEG-LIETSP------PILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNT 1715
L + ++ + D G Y C V + R T+ + + I P E+ + G+ + C G P ++ +L+ ++ IG L+I + G YIC+ + + + + + L+ + I I + A + GE S RC V Q ++ W + I D ++ I + + N GTY+CVAS P G + +SI RES T GP V+V G+ L C+ ++G W+ N +K + +P+ + ++L I + G Y C E + V+++ G + T P P+ V EG + HC P + W+ +R +P R +++N + VL DSG YIC N I++ + T+ P ++ VR G+ + ++C + T
Sbjct: 1864 LTVPNMKRSDGGTYLCVGTNAVGSSEARIEVTV-----VKGNDVSIQPSEASVVEGETLDLNCFVPGNPPPSVTWSRANGYLSPNHQVIGTQ--LRILRASQEDSGEYICRVDGGPHVRQASVSVSVTSESSRLQSPI---ISIEPHSAAVKLGEPASFRCRVHSGAQPVRLEWKLTNNQPIPDNAKISPDGSVITITNAQSKNKGTYRCVASN--PFG----ITQSIVSL-IVRESPRATVTPTGP-VHVKVGDPINLECQ---AAGEPRPSVSWHRLDNARKTMLSSPVPMESN------AVLQILVARAEDSGTYVCTAQNNQGTTETRIEVIVEGGPAVPTVPRASVREPMKVVVEGSTTTLHCDGYGFP---KPTISWS------KLRAPLP-WRHKIVNGSL-------VLPSVGRQDSGQYICNVTNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAHGT 2296
BLAST of low density lipoprotein receptor-1 vs. Ensembl Cavefish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 125.946 bits (315), Expect = 9.443e-29 Identity = 79/220 (35.91%), Postives = 104/220 (47.27%), Query Frame = 3
Query: 1941 FCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKN 2594
CQNG+C+ CD C D SDE + C P CE N L W CDG+ DC + DE +C + C + F C SD IP Y CDE DC+ DE GC P +T V A + VT TC+A G P P++ WR NWG I S+R + + +LTI+D K GD G Y CEA++++ F+ V+ N
Sbjct: 202 MCQNGQCISRDYLCDGERDCTDGSDE--MKCGTPSP----CEPNEFKCKNGRCALKLWRCDGDNDCKDNSDEMDCPVRRPGDACAPEQFVCLSDRACIPASYQCDEEPDCADRSDEYGCAPPTVTSPPEDSVTAMRGGTVTFTCKAVGVPTPIITWRLNWGHIPVSSRITMT-----SENGQGTLTIRDVKEGDQGAYTCEAINAKGLVFAIPDGVLTLN 410 HSP 2 Score: 75.8702 bits (185), Expect = 2.154e-13 Identity = 114/525 (21.71%), Postives = 188/525 (35.81%), Query Frame = 3
Query: 270 INIACNVTNYALNETSIRWLDKDGKVA-------AANRYLYIKSLLKQDEGIYNCSVEKVKDP-QIRFNRTLHLKITIPSISIDILPEESLKI---GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHR-GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRL-DGQYVSMLVISDISQINEGNYECRVGSSIKEVN-----LIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQT----SFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNK 1763
IN+ C S LD K +N L I +D G Y C+ + + + R + +P++ + E +K+ G C G P+ TI L ++K + + +L P V G+YIC T+ + + + L + ++ + R GE L+C +++ W K + E L I D+ GTYKCVAS ++ G + M + + L+ + PQV V G E C +++G + EW G G +P + + DG +L I ++ + NEG Y CR SS + I L + +I + V G SVEF C+ P P RW + ++ D + +++ +D+G Y CT N + +V+ + + P V G C ASG P + T +K
Sbjct: 2243 INLECQAAGEPRPSVSWHRLDNARKTMLSSPVPMESNAVLQILVARAEDSGTYVCTAQNNQGTTETRIEVIVEGGPAVPTVPRASV-REPMKVVVEGSTTTLHCDGYGFPKPTISWSKLRAPLPWRHKIVNGSLVL--PSVGRQDSGQYICNV----TNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAH-GTPPLRFEWSKVGGVLPATAEQQGGDLQINLASPDDAGTYKCVASNKV--GHSEAMAKV--------SVRSPLSVRVSPQVDVKALGSAAEFTC---SANGGPDIKLEWLKEG-----GALPPNHHVRDG----VLRIENLEKSNEGVYICRATSSYGQAQDSARLTIQALPKVMINVRTSVQTVMVGNSVEFECQAVGEPK---------------------PTIRWSKVGGKLPDHVQVKGGMLRIIQVTEADAGQYRCTATNDVGSVQSTVVLSIQSLPQIATQPETKEVTVGSNAVFPCI-------ASGYPVPTITWSK 2709 HSP 3 Score: 71.633 bits (174), Expect = 4.237e-12 Identity = 109/500 (21.80%), Postives = 192/500 (38.40%), Query Frame = 3
Query: 318 IRWLDKDGKVAAANRY-------LYIKSLLKQDEGIYNC-SVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQ-----YKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTW-------YKKDEFIGNDQELV-IKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYI--NGKK-FKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV--GSSIKEVNLIVLLDEG-LIETSP------PILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNT 1715
+ W + G + R L + ++ + D G Y C V + R T+ + + I P E+ + G+ + C G P ++ +L+ ++ IG L+I + G YIC+ + + + + + L+ + I I + A + GE S RC V Q ++ W + I D ++ I + + N GTY+CVAS P G + +SI RES T GP V+V G+ L C+ ++G W+ N +K + +P+ + ++L I + G Y C E + V+++ G + T P P+ V EG + HC P + W+ +R +P R +++N + VL DSG YIC N I++ + T+ P ++ VR G+ + ++C + T
Sbjct: 1982 LTWKKRGGTLPPQARVERTDFGTLTVPNMKRSDGGTYLCVGTNAVGSSEARIEVTV-----VKGNDVSIQPSEASVVEGETLDLNCFVPGNPPPSVTWSRANGYLSPNHQVIGTQ--LRILRASQEDSGEYICRVDGGPHVRQASVSVSVTSESSRLQSPI---ISIEPHSAAVKLGEPASFRCRVHSGAQPVRLEWKLTNNQPIPDNAKISPDGSVITITNAQSKNKGTYRCVASN--PFG----ITQSIVSL-IVRESPRATVTPTGP-VHVKVGDPINLECQ---AAGEPRPSVSWHRLDNARKTMLSSPVPMESN------AVLQILVARAEDSGTYVCTAQNNQGTTETRIEVIVEGGPAVPTVPRASVREPMKVVVEGSTTTLHCDGYGFP---KPTISWS------KLRAPLP-WRHKIVNGSL-------VLPSVGRQDSGQYICNVTNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAHGT 2437 HSP 4 Score: 70.8626 bits (172), Expect = 6.692e-12 Identity = 100/450 (22.22%), Postives = 171/450 (38.00%), Query Frame = 3
Query: 504 PEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPV-----VDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSY---KIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQE--------LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVH-------RGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV--GSSIKEVNLIVL-------LDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPR-EIRVRAGQRVDIECFSKNTQGRASGNPEFSFT 1754
P +++ G + + +C+ G P + W K I + +++ V VD S G YIC+ + A YV+ SV Y +++ GE L C + TW K+ + L + + K+ + GTY CV + + S E++IE+T G V + GE +L+C + GN W NG + +++ G + L I SQ + G Y CRV G +++ ++ V L +I P VK G+ F CRV + + V L+W + + IPD N +I+ S I + A+ + G Y C N ++ + ++ T+TP + V+ G +++EC +A+G P S +
Sbjct: 1864 PVLTIQQGQRAEFRCTASGNPAPAV------EWTGGPGKRISSNAVIRGGVLTFTSVDRSDEGDYICRALNTHGEHTARAVLYVH-STSVPYLLPHVQVSPQQVELHEGETLRLYCRAG-GTPSPGLTWKKRGGTLPPQARVERTDFGTLTVPNMKRSDGGTYLCVGTNAVGS----------------SEARIEVTVVKGNDVSIQPSEASVVEGETLDLNCFV---PGNPPPSVTW-----SRANGYLSPNHQVIG---TQLRILRASQEDSGEYICRVDGGPHVRQASVSVSVTSESSRLQSPIISIEPHSAAVKLGEPASFRCRVHS--GAQPVRLEWKLTNNQ-----PIPD------NAKISPDGSVITITNAQSKNKGTYRCVASNPFGITQSIVSLIVRESPRATVTPTGPVHVKVGDPINLEC-------QAAGEPRPSVS 2258 HSP 5 Score: 64.6994 bits (156), Expect = 5.444e-10 Identity = 71/319 (22.26%), Postives = 131/319 (41.07%), Query Frame = 3
Query: 903 LVIKSFKKDNVGTYKCVAS-----------LQLPSGKLDLMEESIQQFAFFRE----SKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYIN-GKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSS-----------IKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEV--SDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG 1772
L I++ + ++ G Y C S L + ++ + + F R+ S+ T +P P + + +G++ E C T+SGN EW GK+ + + + G +L + + + +EG+Y CR ++ + ++ LL ++ SP +++ EG+++ +CR PS L W + + G + P +R ++T F L + SD G Y+C N + I + N ++I P E V G+ +D+ CF GNP S T ++ G
Sbjct: 1798 LTIQNVQPEDYGVYVCTGSNMFGMDESSAVLHVQEANAEMFYTAYEMFEGHRQPGEGSQPVATIQP-PVLTIQQGQRAEFRC---TASGNPAPAVEWTGGPGKRISSNAV-----IRG---GVLTFTSVDRSDEGDYICRALNTHGEHTARAVLYVHSTSVPYLLPH--VQVSPQQVELHEGETLRLYCRAGGTPS---PGLTW--KKRGGTLP---PQAR--------VERTDFGTLTVPNMKRSDGGTYLCVGTNAVGSSEARIEVTVVKGNDVSIQPSEASVVEGETLDLNCF-------VPGNPPPSVTWSRANG 2079 HSP 6 Score: 53.9138 bits (128), Expect = 1.069e-6 Identity = 109/499 (21.84%), Postives = 183/499 (36.67%), Query Frame = 3
Query: 210 PNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVA----AANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDI--------LPEE-SLKIGGQIKRQCSDLGLP----QETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIG-----NDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLD-EGL--IETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVS--DSGYYICTEPNGQ---TARSELIV 1616
P + ++ V E + C+ Y + +I W + N L + S+ +QD G Y C+V T H+ + +I +D+ LP++ S+++G I+ QC G P + + V QQ LQI + G Y C +K EA V+++ +S ++ + F+ P +IK W K+ + D L I++ +K N G Y C A+ + D +IQ K+ + + Q V G E C+ + G W G G +P ++ G ML I +++ + G Y C + + V V+L + L I T P +V G + F C P + W+ +++ L ++ D VL +V+ DSG Y+CT N Q A ++LIV
Sbjct: 2321 PTVPRASVREPMKVVVEGSTTTLHCD--GYGFPKPTISWSKLRAPLPWRHKIVNGSLVLPSVGRQDSGQYICNV------------TNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAHGTPPLRFEWSKVGGVLPATAEQQGGD------LQINLASPDDAGTYKCVASNKVGHS--EAMAKVSVRSPLSVRVSPQVDVKALGSAAEFTCSANGGP---DIKLEWLKEGGALPPNHHVRDGVLRIENLEKSNEGVYICRATSSYGQAQ-DSARLTIQALP-----KVMINVRTSVQT-VMVGNSVEFECQ---AVGEPKPTIRWSKVG-----GKLPDHVQVKG---GMLRIIQVTEADAGQYRCTATNDVGSVQSTVVLSIQSLPQIATQPETKEVTVGSNAVFPCIASGYPVP---TITWSKDAE--LPPKSVQDGH---------------VLTVPDVTHEDSGTYVCTASNKQGKVQAFTKLIV 2756
BLAST of low density lipoprotein receptor-1 vs. Ensembl Cavefish
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:ZFIN;Acc:ZDB-GENE-080807-4]) HSP 1 Score: 125.561 bits (314), Expect = 1.091e-28 Identity = 77/211 (36.49%), Postives = 101/211 (47.87%), Query Frame = 3
Query: 1941 FCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-CGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFS 2567
CQNG+C+ CD C D SDE + C P CE N L W CDG+ DC + DE +C + C + F C SD IP Y CDE DC+ DE GC P +T V A + VT TC+A G P P++ WR NWG I S+R + + +LTI+D K GD G Y CEA++++ F+
Sbjct: 202 MCQNGQCISRDYLCDGERDCTDGSDE--MKCGTPSP----CEPNEFKCKNGRCALKLWRCDGDNDCKDNSDEMDCPVRRPGDACAPEQFVCLSDRACIPASYQCDEEPDCADRSDEYGCAPPTVTSPPEDSVTAMRGGTVTFTCKAVGVPTPIITWRLNWGHIPVSSRITMT-----SENGQGTLTIRDVKEGDQGAYTCEAINAKGLVFA 401 HSP 2 Score: 75.485 bits (184), Expect = 2.303e-13 Identity = 114/525 (21.71%), Postives = 188/525 (35.81%), Query Frame = 3
Query: 270 INIACNVTNYALNETSIRWLDKDGKVA-------AANRYLYIKSLLKQDEGIYNCSVEKVKDP-QIRFNRTLHLKITIPSISIDILPEESLKI---GGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQE-----LVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHR-GEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRL-DGQYVSMLVISDISQINEGNYECRVGSSIKEVN-----LIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQT----SFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNK 1763
IN+ C S LD K +N L I +D G Y C+ + + + R + +P++ + E +K+ G C G P+ TI L ++K + + +L P V G+YIC T+ + + + L + ++ + R GE L+C +++ W K + E L I D+ GTYKCVAS ++ G + M + + L+ + PQV V G E C +++G + EW G G +P + + DG +L I ++ + NEG Y CR SS + I L + +I + V G SVEF C+ P P RW + ++ D + +++ +D+G Y CT N + +V+ + + P V G C ASG P + T +K
Sbjct: 2206 INLECQAAGEPRPSVSWHRLDNARKTMLSSPVPMESNAVLQILVARAEDSGTYVCTAQNNQGTTETRIEVIVEGGPAVPTVPRASV-REPMKVVVEGSTTTLHCDGYGFPKPTISWSKLRAPLPWRHKIVNGSLVL--PSVGRQDSGQYICNV----TNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAH-GTPPLRFEWSKVGGVLPATAEQQGGDLQINLASPDDAGTYKCVASNKV--GHSEAMAKV--------SVRSPLSVRVSPQVDVKALGSAAEFTC---SANGGPDIKLEWLKEG-----GALPPNHHVRDG----VLRIENLEKSNEGVYICRATSSYGQAQDSARLTIQALPKVMINVRTSVQTVMVGNSVEFECQAVGEPK---------------------PTIRWSKVGGKLPDHVQVKGGMLRIIQVTEADAGQYRCTATNDVGSVQSTVVLSIQSLPQIATQPETKEVTVGSNAVFPCI-------ASGYPVPTITWSK 2672 HSP 3 Score: 70.8626 bits (172), Expect = 6.357e-12 Identity = 106/477 (22.22%), Postives = 186/477 (38.99%), Query Frame = 3
Query: 366 LYIKSLLKQDEGIYNC-SVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQ-IKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQ-----YKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTW-------YKKDEFIGNDQELV-IKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYI--NGKK-FKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRV--GSSIKEVNLIVLLDEG-LIETSP------PILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNT 1715
L + ++ + D G Y C V + R T+ + + I P E+ + G+ + C G P ++ +L+ ++ IG L+I + G YIC+ + + + + + L+ + I I + A + GE S RC V Q ++ W + I D ++ I + + N GTY+CVAS P G + +SI RES T GP V+V G+ L C+ ++G W+ N +K + +P+ + ++L I + G Y C E + V+++ G + T P P+ V EG + HC P + W+ +R +P R +++N + VL DSG YIC N I++ + T+ P ++ VR G+ + ++C + T
Sbjct: 1968 LTVPNMKRSDGGTYLCVGTNAVGSSEARIEVTV-----VKGNDVSIQPSEASVVEGETLDLNCFVPGNPPPSVTWSRANGYLSPNHQVIGTQ--LRILRASQEDSGEYICRVDGGPHVRQASVSVSVTSESSRLQSPI---ISIEPHSAAVKLGEPASFRCRVHSGAQPVRLEWKLTNNQPIPDNAKISPDGSVITITNAQSKNKGTYRCVASN--PFG----ITQSIVSL-IVRESPRATVTPTGP-VHVKVGDPINLECQ---AAGEPRPSVSWHRLDNARKTMLSSPVPMESN------AVLQILVARAEDSGTYVCTAQNNQGTTETRIEVIVEGGPAVPTVPRASVREPMKVVVEGSTTTLHCDGYGFP---KPTISWS------KLRAPLP-WRHKIVNGSL-------VLPSVGRQDSGQYICNVTNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAHGT 2400 HSP 4 Score: 62.3882 bits (150), Expect = 2.272e-9 Identity = 74/335 (22.09%), Postives = 130/335 (38.81%), Query Frame = 3
Query: 903 LVIKSFKKDNVGTYKCVAS-----------LQLPSGKLDLMEESIQQFAFFRE----SKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYIN-GKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSS-----------IKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEG--LVRNNIPDSRWQLMNDEIAD--------------QTSFIVLMKAEV--SDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIG 1772
L I++ + ++ G Y C S L + ++ + + F R+ S+ T +P P + + +G++ E C T+SGN EW GK+ + + + G +L + + + +EG+Y CR ++ + ++ LL ++ SP +++ EG+++ +CR PS L W K G L IP + D +T F L + SD G Y+C N + I + N ++I P E V G+ +D+ CF GNP S T ++ G
Sbjct: 1735 LTIQNVQPEDYGVYVCTGSNMFGMDESSAVLHVQEANAEMFYTAYEMFEGHRQPGEGSQPVATIQP-PVLTIQQGQRAEFRC---TASGNPAPAVEWTGGPGKRISSNAV-----IRG---GVLTFTSVDRSDEGDYICRALNTHGEHTARAVLYVHSTSVPYLLPH--VQVSPQQVELHEGETLRLYCRAGGTPS---PGLTWK---KRGGTLPPQAIPSHGFHQFKSNSLDVLQRRIEELQARVERTDFGTLTVPNMKRSDGGTYLCVGTNAVGSSEARIEVTVVKGNDVSIQPSEASVVEGETLDLNCF-------VPGNPPPSVTWSRANG 2042 HSP 5 Score: 53.5286 bits (127), Expect = 1.153e-6 Identity = 109/499 (21.84%), Postives = 183/499 (36.67%), Query Frame = 3
Query: 210 PNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVA----AANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDI--------LPEE-SLKIGGQIKRQCSDLGLP----QETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIG-----NDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLD-EGL--IETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVS--DSGYYICTEPNGQ---TARSELIV 1616
P + ++ V E + C+ Y + +I W + N L + S+ +QD G Y C+V T H+ + +I +D+ LP++ S+++G I+ QC G P + + V QQ LQI + G Y C +K EA V+++ +S ++ + F+ P +IK W K+ + D L I++ +K N G Y C A+ + D +IQ K+ + + Q V G E C+ + G W G G +P ++ G ML I +++ + G Y C + + V V+L + L I T P +V G + F C P + W+ +++ L ++ D VL +V+ DSG Y+CT N Q A ++LIV
Sbjct: 2284 PTVPRASVREPMKVVVEGSTTTLHCD--GYGFPKPTISWSKLRAPLPWRHKIVNGSLVLPSVGRQDSGQYICNV------------TNHMGTSEATIMLDVETTPYTTLLPDDVSVRVGEVIRLQCLAHGTPPLRFEWSKVGGVLPATAEQQGGD------LQINLASPDDAGTYKCVASNKVGHS--EAMAKVSVRSPLSVRVSPQVDVKALGSAAEFTCSANGGP---DIKLEWLKEGGALPPNHHVRDGVLRIENLEKSNEGVYICRATSSYGQAQ-DSARLTIQALP-----KVMINVRTSVQT-VMVGNSVEFECQ---AVGEPKPTIRWSKVG-----GKLPDHVQVKG---GMLRIIQVTEADAGQYRCTATNDVGSVQSTVVLSIQSLPQIATQPETKEVTVGSNAVFPCIASGYPVP---TITWSKDAE--LPPKSVQDGH---------------VLTVPDVTHEDSGTYVCTASNKQGKVQAFTKLIV 2719
BLAST of low density lipoprotein receptor-1 vs. Ensembl Cavefish
Match: lrp2a (low density lipoprotein receptor-related protein 2a [Source:ZFIN;Acc:ZDB-GENE-050119-2]) HSP 1 Score: 74.7146 bits (182), Expect = 4.522e-13 Identity = 47/123 (38.21%), Postives = 62/123 (50.41%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPI-----TCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
C +G C+ ++ CD N C D SDED + R C + C +NNQ P++ W+CDG+ DC + YDE QNC + +C FTCS+ I Y CD DC DE GCT
Sbjct: 2899 CDDGRCIASSWICDGDNDCGDMSDEDQRHNCGESNRTCSSLEFTC-VNNQP-PQRKCIPRDWVCDGDADCSDAYDEHQNC---TRRSCSANEFTCSNGLCIRSSYRCDRRNDCGDSSDEQGCT 3016 HSP 2 Score: 73.9442 bits (180), Expect = 7.450e-13 Identity = 41/120 (34.17%), Postives = 62/120 (51.67%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C NG+C+ + CD ++ C D SDE C + C N + +P+ +W CDG DC +G DE+ C + C F+C++++ IPR ++CD + DC G DET C S
Sbjct: 1019 CSNGKCVPQSYRCDGVDDCHDNSDEASCGANNSTCSSTAFTCA-NQRCVPR------NWRCDGHNDCFDGSDERECPTQTPGTCQADQFSCANHRCIPRTWLCDTDNDCGDGSDETNCDS 1131 HSP 3 Score: 69.707 bits (169), Expect = 1.426e-11 Identity = 43/121 (35.54%), Postives = 56/121 (46.28%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C G C+ CD C D SDE C+ +C + + +P+ W+CD EEDC +G DE Q+C G C FTC++ IP Y CD DCS G DE C P+
Sbjct: 31 CGTGRCIPAGWHCDGTADCTDDSDESGCPQSTCEAGQFQCLSDGECIPEL------WLCDDEEDCEDGSDERQHCPG---RTCSSSQFTCTNGACIPGEYRCDHLPDCSDGADERNCHYPE 142 HSP 4 Score: 69.707 bits (169), Expect = 1.619e-11 Identity = 42/120 (35.00%), Postives = 63/120 (52.50%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C NG C ++ CD++ +C D SDE T R C +C N + +P+ ++CD ++DCG+ DEQNC + C G +FTC + I + ++CD DC DE GC + Q
Sbjct: 148 CANGACYNRSQHCDQVLNCRDGSDEANCTQR-CSSGQFQCS-NGECVPRG------YVCDHDDDCGDRSDEQNC---TYPTCRGTYFTCPSGRCIHQVWLCDGEDDCGDNADERGCDNVQ 256 HSP 5 Score: 69.707 bits (169), Expect = 1.647e-11 Identity = 66/250 (26.40%), Postives = 95/250 (38.00%), Query Frame = 3
Query: 1560 GYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDE------DPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
G C P+ P + P +++ Q+ +E S G+ FS +N K + + ++ V H DN+ + C SS + C N C+ CD N C D SDE P TC+ D S N++ +P+ W+CD + DCG+G DE NCD S+ C F C D++ I YVCD + DC G DE C
Sbjct: 956 GSNFCNRPSNPNGDCSHFCFPAPYSQRVCGCPYGMKLAPNQQTCLEDPSNEPPTLQCGSNSFSCSNGKCVPQS--YRCDGVDDCH------------DNSDEASCGANNSTCSSTAFT----------CANQRCVPRNWRCDGHNDCFDGSDERECPTQTPGTCQA-DQFSCA---NHRCIPRT------WLCDTDNDCGDGSDETNCD--SIGTCHPGQFQCPDHRCIDPAYVCDGDRDCVDGADEQDC 1169 HSP 6 Score: 67.0106 bits (162), Expect = 1.006e-10 Identity = 49/125 (39.20%), Postives = 61/125 (48.80%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC----RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE---QNCDGFSLNNCGGKFFTCSDN-----KTIPRGYVCDENIDCSQGEDE 2282
C +G C+ +CD+ CAD SDE P TC R C+ +C+ I WICDG+ DCG+ DE NC G S C FTC +N K IPR +VCD + DCS DE
Sbjct: 2857 CTSGRCIPAHWYCDEGTDCADGSDE-PSTCTTMVRTCNSDQFRCDDGRCIASS-------WICDGDNDCGDMSDEDQRHNC-GESNRTCSSLEFTCVNNQPPQRKCIPRDWVCDGDADCSDAYDE 2972 HSP 7 Score: 67.0106 bits (162), Expect = 1.076e-10 Identity = 45/140 (32.14%), Postives = 59/140 (42.14%), Query Frame = 3
Query: 1878 LEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
L R S + + C G C NGEC+ CD + C D+SDE T C C P W+CDGE+DCG+ DE+ CD G++ S IP ++CD C GEDE T+
Sbjct: 164 LNCRDGSDEANCTQRCSSGQFQCSNGECVPRGYVCDHDDDCGDRSDEQNCTYPTCRGTYFTC-------PSGRCIHQVWLCDGEDDCGDNADERGCDNVQRECFPGEWPCPSSGVCIPMEHLCDGTPHCPDGEDENNSTA 296 HSP 8 Score: 66.6254 bits (161), Expect = 1.318e-10 Identity = 45/129 (34.88%), Postives = 66/129 (51.16%), Query Frame = 3
Query: 1914 SDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH-W-ICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
S C PG C NG C+ + CD + C D SDE PI EC + +C+ + + NY + W +C+G DC + DEQNC+ + + G F C +++ IP + CD + DC G DE C+
Sbjct: 3619 SRTCRPGQFKCSNGRCIPQSWKCDVDDDCGDNSDE-PID--ECMGPAYRCDNHTEFDCVTNYRCVPLWALCNGHNDCRDNSDEQNCEELTCDPAGD--FRCDNHQCIPLRWKCDGDNDCGDGSDERNCS 3742 HSP 9 Score: 62.003 bits (149), Expect = 2.957e-9 Identity = 41/115 (35.65%), Postives = 55/115 (47.83%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
N C+ C+ N C D SDE CDP +C+ N+Q +P + W CDG+ DCG+G DE+NC S C + C + IP +VCD + DC DE C
Sbjct: 3676 NYRCVPLWALCNGHNDCRDNSDEQNCEELTCDPAGDFRCD-NHQCIP------LRWKCDGDNDCGDGSDERNC---SPRACTESEYRCDNLHCIPDRWVCDHDNDCEDNSDERDC 3780 HSP 10 Score: 60.8474 bits (146), Expect = 7.364e-9 Identity = 40/119 (33.61%), Postives = 54/119 (45.38%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C NG C+ CD + C+D +DE EC + +C N + + CD +C +G DE NC C F CS+ + +PRGYVCD + DC DE CT P
Sbjct: 111 CTNGACIPGEYRCDHLPDCSDGADERNCHYPECSEL--RCA-NGACYNRSQH------CDQVLNCRDGSDEANC----TQRCSSGQFQCSNGECVPRGYVCDHDDDCGDRSDEQNCTYP 216 HSP 11 Score: 60.8474 bits (146), Expect = 7.618e-9 Identity = 38/121 (31.40%), Postives = 49/121 (40.50%), Query Frame = 3
Query: 1923 CPPGYRFCQNGE-CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C P + CQ+ C+ + CD N C D SDE P C S C N HW CD DC +G DE + + C F C D + I ++CD + DC DE
Sbjct: 2808 CQPEHTKCQSTNICIPRSYLCDGDNDCGDMSDESPTHC-----ASSTCSQNEFRCTSGRCIPAHWYCDEGTDCADGSDEPSTCTTMVRTCNSDQFRCDDGRCIASSWICDGDNDCGDMSDE 2923 HSP 12 Score: 60.077 bits (144), Expect = 1.412e-8 Identity = 38/124 (30.65%), Postives = 55/124 (44.35%), Query Frame = 3
Query: 1926 PPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
P G C N +C+ CD N C D SDE + R C +C+ N +P + W+CD + DC + DE++C+ L C +F C + + CD N DC DE C +
Sbjct: 3708 PAGDFRCDNHQCIPLRWKCDGDNDCGDGSDERNCSPRACTESEYRCD-NLHCIPDR------WVCDHDNDCEDNSDERDCE---LRTCHPGYFQCDSGHCVAERFKCDGNADCLDFTDEMSCPT 3821 HSP 13 Score: 59.6918 bits (143), Expect = 1.744e-8 Identity = 48/175 (27.43%), Postives = 67/175 (38.29%), Query Frame = 3
Query: 1902 KIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDP-----------ISR-------------------------------KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE-TGCTS 2297
++ C P C NG C+ CD N C D SDE+ R CDP I+R KC+ N +P+ ++CDG+ DCG+ DE S + C F C+ + IP + CDE DC+ G DE + CT+
Sbjct: 2720 RVCAFHTCEPTVFTCGNGRCVPYHYRCDHYNDCGDNSDEEGCVFRPCDPDTEFTCNNGRCIAREYVCNGFNNCYDNGTSDEQNCPERTCQPEHTKCQSTNICIPRS------YLCDGDNDCGDMSDESPTHCAS-STCSQNEFRCTSGRCIPAHWYCDEGTDCADGSDEPSTCTT 2887 HSP 14 Score: 58.5362 bits (140), Expect = 4.127e-8 Identity = 39/120 (32.50%), Postives = 51/120 (42.50%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C G C +G C C+ C D SDED + C + +CE + K W CDGE DCG+ DE S C F CS+ + IP+ + CD + DC DE
Sbjct: 3540 CRLGQFQCNDGNCTSPHFLCNSNQDCPDGSDEDTVLC-----ATHQCEAHQWQCNNKRCIPEAWQCDGENDCGDNSDEDP-SHCSSRTCRPGQFKCSNGRCIPQSWKCDVDDDCGDNSDE 3653 HSP 15 Score: 56.9954 bits (136), Expect = 1.081e-7 Identity = 41/125 (32.80%), Postives = 55/125 (44.00%), Query Frame = 3
Query: 1932 GYRF-CQNG-ECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
GY F C NG +C+ + CD + C D+SDE I C P E Q + W CDG DC +G DE + C F C + + R ++CD + DC G DE C +P
Sbjct: 1175 GYEFKCANGHQCINSFYRCDGVFDCNDRSDE--IGCPTRPPGMCHHESEFQCQSDGSCIPAAWECDGHPDCEDGSDEHH--ACPPRTCPTSLFRCDNGNCVFRSWLCDGDNDCRDGSDERDCPTP 1295 HSP 16 Score: 55.0694 bits (131), Expect = 4.701e-7 Identity = 36/117 (30.77%), Postives = 54/117 (46.15%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG C+ ++ CD+ N C D SDE T + C C+ N + + ++CDG+ DCG+ DE + C + C + +P VCD + DC+ DE GC
Sbjct: 2988 CSNGLCIRSSYRCDRRNDCGDSSDEQGCTYQSCQQHQFTCQ-NGRCISSD------FVCDGDNDCGDESDELDHLCRTPAPTCPPGNYRCENGNCVPASQVCDHSDDCNDNSDEKGC 3097
BLAST of low density lipoprotein receptor-1 vs. Ensembl Sea Lamprey
Match: lrp1ab (low density lipoprotein receptor-related protein 1Ab [Source:ZFIN;Acc:ZDB-GENE-030131-7126]) HSP 1 Score: 72.7886 bits (177), Expect = 3.431e-13 Identity = 45/122 (36.89%), Postives = 60/122 (49.18%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C PG C+NG C++ CD N C D SDE P C + C KC+ NN+ +P + W+CDG+ DCGN DE N + C F+C+ IP + CD + DC DE
Sbjct: 827 CHPGEFACKNGRCIQERWRCDGDNDCLDNSDEAPEICHQHTCPSDRFKCQ-NNRCIP------LRWLCDGDNDCGNSEDESN-TTCAARTCPPNQFSCASGHCIPMSWKCDLDDDCGDRSDE 940 HSP 2 Score: 69.707 bits (169), Expect = 3.120e-12 Identity = 45/121 (37.19%), Postives = 60/121 (49.59%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDE 2282
C PG C+NG C A CD N C D SDE C P KC ++ +P + C+G+++CG+G DE++C + C F CS K IPR +VCD + DC G DE
Sbjct: 3343 CRPGQFQCKNGICTNPAFICDGDNDCGDGSDEANCDVHVCLPSQFKCRTTHRCIPGI------FRCNGQDNCGDGEDEKDCPEVT---CAPNQFQCSSTKRCIPRVWVCDRDNDCGDGSDE 3454 HSP 3 Score: 66.6254 bits (161), Expect = 2.518e-11 Identity = 42/125 (33.60%), Postives = 55/125 (44.00%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C P C+N C+ CD N C D SDE+ T R C C I + W CDG+ DC +G DE++C C F C + IP+ + CD +IDC G DE C +
Sbjct: 3505 CEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEEGCTPRPCSESEFSCANGRCIAGR-------WRCDGDHDCSDGSDEKDCS----PRCDHDQFQCRNGHCIPQRWRCDADIDCIDGSDEDNCAA 3618 HSP 4 Score: 64.3142 bits (155), Expect = 1.203e-10 Identity = 50/166 (30.12%), Postives = 66/166 (39.76%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDE----------DPITCRE---------------CDPISRK-------CEINNQILPKKNYF----------LIHWICDGEEDCGNGYDEQNCDGFSLN-NCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C GY C NG C+E K C+ +N C D SDE D C + CD IS + C +++ + + + L WICDG DCG+ DE+NC S + C +F C IP + CD DC G DE C
Sbjct: 2543 CKNGYVNCLNGRCMETLKLCNGVNDCGDNSDEIACNNSTCGADEFRCGDGSCIANVTRCNQVVDCDDISDEIGCGPMNCTHYHRLGVQASGYVSCNSTSLCVLPAWICDGANDCGDYADEKNCKKKSGSPGCSPDYFNCPSGPCIPTAWKCDREPDCDDGADELNC 2708 HSP 5 Score: 61.2326 bits (147), Expect = 1.199e-9 Identity = 55/172 (31.98%), Postives = 83/172 (48.26%), Query Frame = 3
Query: 1788 KISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRF-CQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGC 2291
K++N G ++ L +PGG + + + +GR S S RF C+N +C+ CD + C D+SDE P C + C P +C+ N I + ICDG+ DCG+G DE NCD ++ C F C + ++ IP + C+ +C GEDE C
Sbjct: 3264 KVNNGGCSNLCLISPGGQYKCACPTNFYLASDGRTCLSNCTAS-------RFVCKNDKCIPFWWKCDTEDDCGDRSDE-PADCPDFKCRPGQFQCK--NGICTNPAF-----ICDGDNDCGDGSDEANCD---VHVCLPSQFKCRTTHRCIPGIFRCNGQDNCGDGEDEKDC 3417 HSP 6 Score: 59.3066 bits (142), Expect = 5.040e-9 Identity = 49/131 (37.40%), Postives = 62/131 (47.33%), Query Frame = 3
Query: 1923 CPPGYRF-CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSL-----NNCGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGC 2291
C P +F C NG C+ CD N CAD SDE I C IS+ KC + + +P HW CDG+ DCG+ DE N + L C G F C +D + IP + CD + DC DE C
Sbjct: 949 CFPLTQFACNNGRCINMNWRCDADNDCADASDE--IGCNHSCSISQFKCN-SGRCIPS------HWTCDGDNDCGDFSDETNPNCTKLATRPPGGCHGDEFQCKADGQCIPLRWRCDGDTDCIDTSDEKEC 1070 HSP 7 Score: 58.151 bits (139), Expect = 1.060e-8 Identity = 38/116 (32.76%), Postives = 51/116 (43.97%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG+C+ CD + C DKSDE P C SR+C+ +C+G DCG+ DE C+ + CG F C D I C++ +DC DE GC
Sbjct: 2509 CNNGDCIRYHLTCDGVADCKDKSDEKPFYC-----TSRQCKNGYVNCLNGRCMETLKLCNGVNDCGDNSDEIACNN---STCGADEFRCGDGSCIANVTRCNQVVDCDDISDEIGC 2616 HSP 8 Score: 56.9954 bits (136), Expect = 2.174e-8 Identity = 40/128 (31.25%), Postives = 59/128 (46.09%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRE--------CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKF-FTCSDN-KTIPRGYVCDENIDCSQGEDETGCTS 2297
C +G C+ + CD N C D SDE C + C +C+ + Q +P + W CDG+ DC + DE+ CDG + C F+C D + I + + CD + DC DE GC +
Sbjct: 995 CNSGRCIPSHWTCDGDNDCGDFSDETNPNCTKLATRPPGGCHGDEFQCKADGQCIP------LRWRCDGDTDCIDTSDEKECDGV-VRTCDPTLQFSCRDTGRCISKTWFCDGDNDCEDNSDEEGCET 1115 HSP 9 Score: 53.5286 bits (127), Expect = 2.333e-7 Identity = 41/142 (28.87%), Postives = 59/142 (41.55%), Query Frame = 3
Query: 1878 LEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNC---DGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
L+ + +I CP CQN C+ CD N C + DE TC +R C N + + W CD ++DCG+ DE +C F L F C++ + I + CD + DC+ DE GC
Sbjct: 853 LDNSDEAPEICHQHTCPSDRFKCQNNRCIPLRWLCDGDNDCGNSEDESNTTC-----AARTCPPNQFSCASGHCIPMSWKCDLDDDCGDRSDEPPSCAYPTCFPLTQ-----FACNNGRCINMNWRCDADNDCADASDEIGC 984 HSP 10 Score: 50.8322 bits (120), Expect = 1.894e-6 Identity = 38/118 (32.20%), Postives = 48/118 (40.68%), Query Frame = 3
Query: 1932 GYRFCQNGE-CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
GY C + C+ A CD N C D +DE + P C + P W CD E DC +G DE NCD C F C + K I + ++CD DC DE
Sbjct: 2633 GYVSCNSTSLCVLPAWICDGANDCGDYADEKNCKKKSGSP---GCSPDYFNCPSGPCIPTAWKCDREPDCDDGADELNCDML----CAVDHFECDNGKCITKRWMCDGEDDCGDRSDE 2743 HSP 11 Score: 49.6766 bits (117), Expect = 3.391e-6 Identity = 46/134 (34.33%), Postives = 60/134 (44.78%), Query Frame = 3
Query: 1911 VSDICPPGYRF-CQN-GECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQIL--PKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIP--RGYVCDENIDCSQGEDETGC 2291
V C P +F C++ G C+ FCD N C D SDE+ C P S C ++ I PKK +CDG DC +G DE CD +NN G C+ N T+ G VC G+D+ C
Sbjct: 1073 VVRTCDPTLQFSCRDTGRCISKTWFCDGDNDCEDNSDEEGCETMLCKPPSHSCANDSSICLSPKK-------LCDGHSDCPDGSDEGMLCDQCQVNNGG-----CTHNCTVAPGEGVVCSCPSGMQLGKDKKSC 1194
BLAST of low density lipoprotein receptor-1 vs. Ensembl Sea Lamprey
Match: lrp2a (low density lipoprotein receptor-related protein 2a [Source:ZFIN;Acc:ZDB-GENE-050119-2]) HSP 1 Score: 70.4774 bits (171), Expect = 1.896e-12 Identity = 48/145 (33.10%), Postives = 62/145 (42.76%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDP-----ITC---------RECDPISRK--------------CEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
C NG C+ CD + C D SDE +TC R C PI + C N+ +P+ +WICD + DCG+G DE+ CD C F C D++ I YVCD + DC G DE GC
Sbjct: 1010 CANGRCVPRLFLCDGYDDCHDGSDERGCGTGNVTCSPYAFTCTNRRCIPIDWRPTRLATTCRADQFTCASGNRCIPR------YWICDTDNDCGDGSDERGCD--MSGTCHPMQFQCPDHRCIDNAYVCDGDSDCVDGADERGCV 1146 HSP 2 Score: 69.707 bits (169), Expect = 3.044e-12 Identity = 45/129 (34.88%), Postives = 60/129 (46.51%), Query Frame = 3
Query: 1929 PGYRF-CQNGECLENAKFCDKINHCADKSDED---PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
PG +F C +G C+ + CD N C D SDED R C P C + P++ ++CDG+ DC + DE QNC + +C F C + + Y CD DC G DE GCT P
Sbjct: 2869 PGTQFTCDSGRCIPGSWICDGDNDCGDGSDEDGRHACGARTCGPHEFTCA--DASPPRRRCIQRRFVCDGDADCSDALDEHQNC---TRRSCTAGEFACDNGLCVHSRYRCDRRNDCGDGSDERGCTYP 2992 HSP 3 Score: 68.9366 bits (167), Expect = 4.686e-12 Identity = 41/127 (32.28%), Postives = 59/127 (46.46%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C G C +G C+ + CD IN C+D SDE + C + +C +N+ + + ++CDGE DC + DE QNC G + C FTC+ + + CD DC DE C P
Sbjct: 1 CDSGQFRCGSGACIPRSWVCDSINDCSDDSDERGCSPATCTTLQFRCRSDNRCIARA------FVCDGEADCADRSDEHQNCPG---STCSSSHFTCASGHCVQSAFRCDHFQDCDDRSDEQSCQYP 118 HSP 4 Score: 65.0846 bits (157), Expect = 8.514e-11 Identity = 43/118 (36.44%), Postives = 54/118 (45.76%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSD-----NKTIPRGYVCDENIDCSQGEDE 2282
C NG+C+ + CD C D +DE P +C DP R C WICDG+ DCG+G DE CG FTC+D + I R +VCD + DCS DE
Sbjct: 2833 CGNGQCIPLSWVCDSEQDCTDNADE-PSSCS--DP-GRTCPGTQFTCDSGRCIPGSWICDGDNDCGDGSDEDGRHACGARTCGPHEFTCADASPPRRRCIQRRFVCDGDADCSDALDE 2946 HSP 5 Score: 63.1586 bits (152), Expect = 3.377e-10 Identity = 45/161 (27.95%), Postives = 62/161 (38.51%), Query Frame = 3
Query: 1923 CPPGYRF-CQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEINN-----------------------QILPKKNYFL-------------IHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETG 2288
C P F C NG C+ ++ C+ +N+C D + D C R C P KC N LP F+ + W+CD E+DC + DE + C G FTC + IP ++CD + DC G DE G
Sbjct: 2741 CDPAAEFACTNGRCIARSQVCNGVNNCRDNATSDEQRCPERTCQPGLLKCLTTNICVLRHYLSGGAAEWRRNDLRRPPPLPLHTCFIANEFRCGNGQCIPLSWVCDSEQDCTDNADEPSSCSDPGRTCPGTQFTCDSGRCIPGSWICDGDNDCGDGSDEDG 2901 HSP 6 Score: 62.7734 bits (151), Expect = 3.833e-10 Identity = 44/125 (35.20%), Postives = 58/125 (46.40%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQN--CDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C G C NG C+ + CD+ N C D SDE T C CE N + +P+ + CDG+ DCG+G DE C S C FF C + + VC++ DC+ G DE GC
Sbjct: 2955 CTAGEFACDNGLCVHSRYRCDRRNDCGDGSDERGCTYPTCRQNQFTCE-NGRCIPRI------FACDGDNDCGDGSDEDTHLCHQPS-PTCAPGFFRCGAGECVAIHLVCNQANDCADGSDEKGC 3071 HSP 7 Score: 62.7734 bits (151), Expect = 4.066e-10 Identity = 45/132 (34.09%), Postives = 61/132 (46.21%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRE--CDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDE--QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
CPP C N C+ + CD N C D SDE+ C + C+P R +C+ N I H IC+ +DCG+G DE C + C + F C+ + IP VC+ +C DETGC Q
Sbjct: 3807 CPPSSFECDNHVCIPPSWKCDGDNDCGDGSDEELHHCLDTPCNPPGRFRCDNNRCIYS-------HEICNAVDDCGDGSDETPDKCKEPTFAPCTEEEFKCASGRCIPMAAVCNNYNECRDNTDETGCNQGQ 3931 HSP 8 Score: 62.3882 bits (150), Expect = 4.981e-10 Identity = 39/124 (31.45%), Postives = 56/124 (45.16%), Query Frame = 3
Query: 1926 PPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
P G C N C+ CD+ + C D SDE R C +C N + +P + W+C+ E DCG+ DE++C+ L C +F C IP CD + DC DE+ C +
Sbjct: 3686 PLGDYRCDNHRCIPLRWRCDRYDDCGDGSDERNCAPRPCSESEFRC-TNQRCIPGR------WVCNHENDCGDNSDERDCE---LQTCLPGYFQCGSGHCIPERLKCDGSADCQDFSDESLCPT 3799 HSP 9 Score: 60.077 bits (144), Expect = 2.280e-9 Identity = 36/114 (31.58%), Postives = 54/114 (47.37%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
N C+ C+ ++ C D SDE CDP+ N++ +P + W CD +DCG+G DE+NC + C F C++ + IP +VC+ DC DE C
Sbjct: 3654 NYRCIPTWAVCNGMDDCRDNSDEQGCAEITCDPLGDYRCDNHRCIP------LRWRCDRYDDCGDGSDERNC---APRPCSESEFRCTNQRCIPGRWVCNHENDCGDNSDERDC 3758 HSP 10 Score: 57.3806 bits (137), Expect = 1.791e-8 Identity = 45/128 (35.16%), Postives = 58/128 (45.31%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRE-----CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQ--NCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDET 2285
C PGY C +G C+ CD C D SDE R C P S +C+ + I P W CDG+ DCG+G DE+ +C N G F C +N+ I +C+ DC G DET
Sbjct: 3763 CLPGYFQCGSGHCIPERLKCDGSADCQDFSDESLCPTRYPNGTWCPPSSFECDNHVCIPPS-------WKCDGDNDCGDGSDEELHHCLDTPCNPPG--RFRCDNNRCIYSHEICNAVDDCGDGSDET 3881 HSP 11 Score: 55.4546 bits (132), Expect = 7.278e-8 Identity = 44/140 (31.43%), Postives = 65/140 (46.43%), Query Frame = 3
Query: 1881 EGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLI-HW-ICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
+G S + C PG C NG C+ + CD + C D SDE TC S +C+ + + + NY I W +C+G +DC + DEQ C + + G + C +++ IP + CD DC G DE C
Sbjct: 3586 DGSDEDSATCAARTCAPGQFRCNNGRCIPRSWVCDVDDDCGDGSDEPHDTCMG---PSHRCDSHTEFACRTNYRCIPTWAVCNGMDDCRDNSDEQGCAEITCDPLGD--YRCDNHRCIPLRWRCDRYDDCGDGSDERNCA 3720 HSP 12 Score: 54.6842 bits (130), Expect = 1.188e-7 Identity = 38/127 (29.92%), Postives = 54/127 (42.52%), Query Frame = 3
Query: 1935 YRF-CQNG-ECLENAKFCDKINHCADKSDEDPITCRE---CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
Y+F C +G +C+ CD C D+SDE R C +C+ + +P W CDG DC +G DE G C + C + +P + CD + DC G DE C +P
Sbjct: 1152 YQFSCSSGDQCIATYYRCDGAFDCRDRSDEVGCPTRAPGLCHNDEFQCQSDGLCIPAG------WECDGHPDCDDGSDEH--PGCPPRTCAAGYLRCDNGNCVPESWRCDGDNDCRDGTDERDCPTP 1270 HSP 13 Score: 52.7582 bits (125), Expect = 4.398e-7 Identity = 39/125 (31.20%), Postives = 53/125 (42.40%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDE 2282
+S C P C + C++NA CD + C D +DE C C +Q + ++ CDG DC + DE C + C F C SD IP G+ CD + DC G DE
Sbjct: 1107 MSGTCHPMQFQCPDHRCIDNAYVCDGDSDCVDGADERGCV-FNCTSYQFSCSSGDQCI------ATYYRCDGAFDCRDRSDEVGCPTRAPGLCHNDEFQCQSDGLCIPAGWECDGHPDCDDGSDE 1224
BLAST of low density lipoprotein receptor-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001137.1 (pep scaffold:Pmarinus_7.0:GL476464:95621:179961:-1 gene:ENSPMAG00000001008.1 transcript:ENSPMAT00000001137.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 68.1662 bits (165), Expect = 7.805e-12 Identity = 46/124 (37.10%), Postives = 59/124 (47.58%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC-------RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGC 2291
C+NG C+ + CD N C D SDE TC R+C +C IN +P + W CDG+ DC + DE+ CDG G FTC N I + +VCD + DC DE GC
Sbjct: 157 CKNGHCIPSQWVCDGDNDCGDVSDETH-TCEFPARPLRQCREDEFRCAINGNCIP------LRWRCDGDADCMDISDEKECDGQRRTCNPGTHFTCVSNGICIRKAWVCDGDNDCEDNSDEAGC 273 HSP 2 Score: 63.929 bits (154), Expect = 1.609e-10 Identity = 44/125 (35.20%), Postives = 56/125 (44.80%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C P C+N C+ CD N C D SDE+ T R C C I + W CDG+ DC +G DE++C SL C F C + IP+ + CD + DC G DE C S
Sbjct: 876 CEPYQFRCKNNRCIPGRWHCDYDNDCGDNSDEEGCTPRPCSESEFSCANGRCIAGR-------WRCDGDHDCMDGSDEKDC---SL-RCEQDQFQCQNGHCIPQRWRCDNDADCLDGSDEENCGS 989 HSP 3 Score: 63.929 bits (154), Expect = 1.766e-10 Identity = 42/110 (38.18%), Postives = 59/110 (53.64%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDPITCRECDPISR--KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
C+++ CD N C D SDE P C++ IS KC+ NN+ +P + W+CDG+ DCG DE N ++ C + FTC + K IP + CD + DCS DE
Sbjct: 1 CIQDQWRCDGDNDCQDGSDELPEICQQHTCISDRFKCK-NNRCIP------MRWLCDGDNDCGENEDESN-TTCTVRTCPAEQFTCGNGKCIPIAWKCDLDNDCSDNSDE 102 HSP 4 Score: 60.4622 bits (145), Expect = 1.598e-9 Identity = 43/123 (34.96%), Postives = 59/123 (47.97%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCR--ECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDET 2285
CP C NG+C+ A CD N C+D SDE P +C C P+++ N + + I W CD + DC + DE C+ N C F+C + IP +VCD + DC DET
Sbjct: 71 CPAEQFTCGNGKCIPIAWKCDLDNDCSDNSDEPP-SCAYPTCLPLTQFSCNNGRCIN------IRWRCDSDNDCADSSDEAGCN----NTCADSQFSCKNGHCIPSQWVCDGDNDCGDVSDET 182
BLAST of low density lipoprotein receptor-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003195.1 (pep scaffold:Pmarinus_7.0:GL476689:250750:275904:-1 gene:ENSPMAG00000002894.1 transcript:ENSPMAT00000003195.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 60.8474 bits (146), Expect = 1.375e-9 Identity = 45/125 (36.00%), Postives = 60/125 (48.00%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDP-ITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDET----GCTSPQI 2306
C+ + +CD + CAD+SDE P CR + C N N + WI CDGE DC G DE +C+ C + C S+N+ + YVCD DCS G DE+ GCT+ Q
Sbjct: 477 CIRGSLYCDGVTDCADQSDETPDCACRS----DQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE---REGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCARGCTANQY 594 HSP 2 Score: 53.9138 bits (128), Expect = 1.595e-7 Identity = 49/141 (34.75%), Postives = 59/141 (41.84%), Query Frame = 3
Query: 1905 IYVSDI--CPPGYRFCQNG--ECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
IYV D C C N ECLE CD C+ SDE +R C N N + WI CDGE DC G DE +C+ C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 744 IYVCDGEGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC--------ARGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE----RGCPANLYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 872 HSP 3 Score: 53.5286 bits (127), Expect = 2.358e-7 Identity = 45/127 (35.43%), Postives = 56/127 (44.09%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDET----GCTSPQI 2306
N ECLE CD C+ SDE +R C N N + WI CDGE DC G DE +C+ C + C S+N+ + YVCD DCS G DE+ GCT+ Q
Sbjct: 560 NNECLEWIYVCDGEADCSGGSDESDC--------ARGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE----RGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERGCTANQY 674 HSP 4 Score: 51.9878 bits (123), Expect = 6.483e-7 Identity = 43/122 (35.25%), Postives = 53/122 (43.44%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
N ECLE CD C+ SDE R C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 803 NNECLEWIYVCDGEADCSGGSDESDC--------ERGCPANLYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCPANLYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 914 HSP 5 Score: 51.9878 bits (123), Expect = 6.594e-7 Identity = 42/120 (35.00%), Postives = 52/120 (43.33%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG CL CD C+ SDE R C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C
Sbjct: 354 CGNGSCLGWIYVCDGEADCSGGSDE--------SDCERGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC 463 HSP 6 Score: 51.9878 bits (123), Expect = 7.179e-7 Identity = 48/139 (34.53%), Postives = 63/139 (45.32%), Query Frame = 3
Query: 1923 CPPGYRFCQNG--ECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDET-----GCTSPQI 2306
CP C N ECLE CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ GCT+ Q
Sbjct: 832 CPANLYACNNSNNECLEWIYVCDGEADCSGGSDE-----SDCERV-QGCPANLYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCEREGCTANQY 962 HSP 7 Score: 51.6026 bits (122), Expect = 9.030e-7 Identity = 42/119 (35.29%), Postives = 51/119 (42.86%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCT 2294
N ECLE CD C+ SDE R C N N + WI CDGE DC G DE +C+ C + C S+N+ + YVCD DCS G DE+ C
Sbjct: 600 NNECLEWIYVCDGEADCSGGSDESDC--------ERGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE----RGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCA 706 HSP 8 Score: 51.2174 bits (121), Expect = 1.136e-6 Identity = 44/121 (36.36%), Postives = 57/121 (47.11%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCD-GF--SLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGC 2291
N ECLE CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C+ G L C + C S+N+ + YVCD DCS G DE+ C
Sbjct: 81 NNECLEWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERGMFEHLQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC 195 HSP 9 Score: 50.8322 bits (120), Expect = 1.312e-6 Identity = 45/127 (35.43%), Postives = 54/127 (42.52%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDET----GCTSPQI 2306
N ECLE CD C+ SDE D C N N + WI CDGE DC G DE +C C + C S+N+ + YVCD DCS G DE+ GCT+ Q
Sbjct: 519 NNECLEWIYVCDGEADCSGGSDES-------DCEREGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC----ARGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERGCTANQY 634 HSP 10 Score: 50.8322 bits (120), Expect = 1.346e-6 Identity = 43/120 (35.83%), Postives = 51/120 (42.50%), Query Frame = 3
Query: 1956 ECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
ECLE CD C+ SDE D C N N + WI CDGE DC G DE NC+ C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1 ECLEWIYVCDGEADCSGGSDES-------DCEREGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESNCE---REGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 110 HSP 11 Score: 50.0618 bits (118), Expect = 2.702e-6 Identity = 43/118 (36.44%), Postives = 53/118 (44.92%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGC 2291
N ECLE CD C+ SDE RE C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C
Sbjct: 40 NNECLEWIYVCDGEADCSGGSDESNCE-RE------GCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC 148 HSP 12 Score: 50.0618 bits (118), Expect = 2.725e-6 Identity = 43/140 (30.71%), Postives = 56/140 (40.00%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLN--------------------NCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG CL A CD +N C D +DE + ++ C N N + WI CDGE DC G DE +C+ C + C S+N+ + YVCD DCS G DE+ C
Sbjct: 208 CGNGSCLGIASLCDGVNDCGDFTDESNCS-------NQGCTENQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERGMFEQLCMPLRPNTLWQWELPGNKGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESNC 340
BLAST of low density lipoprotein receptor-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003181.1 (pep scaffold:Pmarinus_7.0:GL476689:240399:277283:-1 gene:ENSPMAG00000002894.1 transcript:ENSPMAT00000003181.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 60.8474 bits (146), Expect = 1.464e-9 Identity = 43/120 (35.83%), Postives = 57/120 (47.50%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDP-ITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C+ + +CD + CAD+SDE P CR + C N N + WI CDGE DC G DE +C + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1077 CIRGSLYCDGVTDCADQSDETPDCACRS----DQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC--ARVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 1190 HSP 2 Score: 58.151 bits (139), Expect = 1.010e-8 Identity = 46/128 (35.94%), Postives = 57/128 (44.53%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDET----GCTSPQ 2303
C NG CL A CD +N C D +DE + C N N + WI CDGE DC G DE +C+ C + C S+N+ + YVCD DCS G DE+ GCT Q
Sbjct: 417 CGNGSCLGIASLCDGVNDCGDFTDESNCI--------QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE----RGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERGCTENQ 532 HSP 3 Score: 55.8398 bits (133), Expect = 4.758e-8 Identity = 42/123 (34.15%), Postives = 59/123 (47.97%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDET----GCTSPQ 2303
C+ + +CD + CAD+SDE P C + + N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ GCT+ Q
Sbjct: 645 CIRGSLYCDGVTDCADQSDETP-----------DCACRSDQIRCGNGSCLGWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERGCTANQ 754 HSP 4 Score: 55.4546 bits (132), Expect = 6.790e-8 Identity = 40/119 (33.61%), Postives = 56/119 (47.06%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C+ + +CD + CAD+SDE P C + + N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 880 CIRGSLYCDGVTDCADQSDETP-----------DCACRSDQIRCGNGSCLGWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 985 HSP 5 Score: 55.4546 bits (132), Expect = 6.790e-8 Identity = 40/119 (33.61%), Postives = 56/119 (47.06%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C+ + +CD + CAD+SDE P C + + N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1238 CIRGSLYCDGVTDCADQSDETP-----------DCACRSDQIRCGNGSCLGWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 1343 HSP 6 Score: 55.0694 bits (131), Expect = 8.903e-8 Identity = 40/119 (33.61%), Postives = 56/119 (47.06%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C+ + +CD + CAD+SDE P C + + N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1594 CIRGSLYCDGLTDCADQSDETP-----------DCACRSDQIRCGNGSCLGWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 1699 HSP 7 Score: 53.1434 bits (126), Expect = 3.280e-7 Identity = 43/122 (35.25%), Postives = 53/122 (43.44%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
N ECLE CD C+ SDE R C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 721 NNECLEWIYVCDGEADCSGGSDESDC--------ERGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 832 HSP 8 Score: 52.373 bits (124), Expect = 5.735e-7 Identity = 43/122 (35.25%), Postives = 56/122 (45.90%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
N ECLE CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C+ C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1314 NNECLEWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE---REGCPANLYACNNSNNECLEWIYVCDGEADCSGGSDESDCERDQ 1426 HSP 9 Score: 51.9878 bits (123), Expect = 6.402e-7 Identity = 43/122 (35.25%), Postives = 57/122 (46.72%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
N ECLE CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1433 NNECLEWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 1546 HSP 10 Score: 51.9878 bits (123), Expect = 7.455e-7 Identity = 43/118 (36.44%), Postives = 55/118 (46.61%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGC 2291
N ECLE CD C+ SDE +C+ + + C N N + WI CDGE DC G DE NC+ C + C S+N+ + YVCD DCS G DE+ C
Sbjct: 1712 NNECLEWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESNCE---REGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC 1820 HSP 11 Score: 51.6026 bits (122), Expect = 8.183e-7 Identity = 45/129 (34.88%), Postives = 60/129 (46.51%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDET-----GCTSPQ 2303
C NG CL CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ GCT+ Q
Sbjct: 912 CGNGSCLGWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCAREGCTANQ 1032 HSP 12 Score: 51.6026 bits (122), Expect = 8.906e-7 Identity = 43/124 (34.68%), Postives = 57/124 (45.97%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C NG CL CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1626 CGNGSCLGWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 1741 HSP 13 Score: 51.6026 bits (122), Expect = 9.370e-7 Identity = 42/122 (34.43%), Postives = 54/122 (44.26%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYV-CDENIDCSQGEDET---GCTSPQI 2306
C+ + +CD + CAD+SDE P C + + N + WI CDGE DC G DE NC+ F C+D K RG + CD DC+ DET C S QI
Sbjct: 117 CIRGSLYCDGVTDCADQSDETP-----------DCACRSDQIRCGNGSCLGWIYVCDGEADCSGGSDESNCE--------RGMFECADKKHCIRGSLYCDGVTDCADQSDETPDCACRSDQI 219 HSP 14 Score: 51.6026 bits (122), Expect = 9.370e-7 Identity = 42/119 (35.29%), Postives = 56/119 (47.06%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCT 2294
N ECLE CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C
Sbjct: 761 NNECLEWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCA 871 HSP 15 Score: 51.2174 bits (121), Expect = 1.371e-6 Identity = 45/133 (33.83%), Postives = 56/133 (42.11%), Query Frame = 3
Query: 1923 CPPGYRFCQNG--ECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
CP C N ECLE CD C+ SDE CE + N + WI CDGE DC G DE +C+ + C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1386 CPANLYACNNSNNECLEWIYVCDGEADCSGGSDE------------SDCERDQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE--RVQGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 1504 HSP 16 Score: 50.8322 bits (120), Expect = 1.783e-6 Identity = 42/122 (34.43%), Postives = 55/122 (45.08%), Query Frame = 3
Query: 1959 CLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYV-CDENIDCSQGEDET---GCTSPQI 2306
C+ + +CD + CAD+SDE P C + + N + WI CDGE DC G DE +C+ G F C+D K RG + CD DC+ DET C S QI
Sbjct: 312 CIRGSLYCDGVTDCADESDETP-----------DCACRSDQIRCGNGSCLGWIYVCDGEADCSGGSDESDCE-------RGMFEHCADKKHCIRGSLYCDGVTDCADQSDETPDCACRSDQI 415 HSP 17 Score: 50.447 bits (119), Expect = 1.876e-6 Identity = 42/118 (35.59%), Postives = 55/118 (46.61%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGC 2291
N ECLE CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C + C + C S+N+ + YVCD DCS G DE+ C
Sbjct: 956 NNECLEWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC---AREGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDC 1064 HSP 18 Score: 50.447 bits (119), Expect = 2.076e-6 Identity = 43/124 (34.68%), Postives = 56/124 (45.16%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C NG CL CD C+ SDE +C+ + + C N N + WI CDGE DC G DE +C+ C + C S+N+ + YVCD DCS G DE+ C Q
Sbjct: 677 CGNGSCLGWIYVCDGEADCSGGSDE-----SDCERV-QGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCE----RGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERVQ 790 HSP 19 Score: 50.447 bits (119), Expect = 2.358e-6 Identity = 42/118 (35.59%), Postives = 51/118 (43.22%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGC 2291
N ECLE CD C+ SDE R C N N + WI CDGE DC G DE +C+ N + C S+N+ + YVCD DCS G DE+ C
Sbjct: 459 NNECLEWIYVCDGEADCSGGSDESDC--------ERGCTANQYACNNSNNECLEWIYVCDGEADCSGGSDESDCERGCTEN----QYACNNSNNECLEWIYVCDGEADCSGGSDESDC 564 HSP 20 Score: 50.0618 bits (118), Expect = 2.746e-6 Identity = 44/122 (36.07%), Postives = 53/122 (43.44%), Query Frame = 3
Query: 1950 NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWI--CDGEEDCGNGYDEQNC--DGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
N ECLE CD C+ SDE D C N N + WI CDGE DC G DE +C D ++ NN S+N+ + YVCD DCS G DE+ C Q
Sbjct: 1356 NNECLEWIYVCDGEADCSGGSDES-------DCEREGCPANLYACNNSNNECLEWIYVCDGEADCSGGSDESDCERDQYACNN--------SNNECLEWIYVCDGEADCSGGSDESDCERVQ 1462
BLAST of low density lipoprotein receptor-1 vs. Ensembl Nematostella
Match: EDO45218 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTH9]) HSP 1 Score: 81.2629 bits (199), Expect = 1.242e-15 Identity = 45/124 (36.29%), Postives = 65/124 (52.42%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
C PG C NG+C+ ++ CD N C D SDE+ C+P KC+ N + + K W CD + DCG+ DE+NC + + C +F C++ + IP +VCD + DC DE CT
Sbjct: 1027 CAPGQFKCGNGKCIPSSWKCDHDNDCGDNSDENNCPYSTCNPSQFKCD-NGRCISSK------WRCDHDNDCGDMSDERNC---TFSTCASNYFRCANQRCIPMRWVCDFDNDCRDNSDERDCT 1140 HSP 2 Score: 76.6406 bits (187), Expect = 3.434e-14 Identity = 45/123 (36.59%), Postives = 60/123 (48.78%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C PG C NG+C+ ++ CD N C D SDE+ C+P KC+ N + + K W CD + DCG+ DE+NC G C F C + K IP + CD + DC DE C
Sbjct: 950 CAPGQFKCGNGKCIPSSWKCDHDNDCGDNSDENNCPYSTCNPSQFKCD-NGRCISSK------WRCDHDNDCGDMSDERNCTG----TCAPGQFKCGNGKCIPSSWKCDHDNDCGDNSDENNC 1061 HSP 3 Score: 73.559 bits (179), Expect = 3.603e-13 Identity = 42/126 (33.33%), Postives = 59/126 (46.83%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C Y C N C+ CD N C D SDE R+C P C N + + W+CD + DC + DE++C + +C F+CS+ + I R +VCD + DC G DE C+ P
Sbjct: 1105 CASNYFRCANQRCIPMRWVCDFDNDCRDNSDE-----RDCTPTFSTCASNYFRCANQRCIPMRWVCDFDNDCRDNSDERDCTP-TGRSCNSGQFSCSNGRCISRSWVCDRDNDCGDGSDERNCSYP 1224 HSP 4 Score: 65.855 bits (159), Expect = 7.860e-11 Identity = 45/140 (32.14%), Postives = 61/140 (43.57%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDE--------DPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG----FSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQI 2306
C G C NG C+ + CD+ N C D SDE P T R PI L + F +CDG +DCG+ DE +C+ F +C F C++ + + CD DC DETGC++P I
Sbjct: 1187 CNSGQFSCSNGRCISRSWVCDRDNDCGDGSDERNCSYPTTGPWTTRPWTPIFSCRSWEFSCLNGRCVFY-RLVCDGVDDCGDSSDEMSCNATATPFVPRSCHYWEFQCANRRCVYNSQRCDGQNDCGDWSDETGCSTPPI 1325 HSP 5 Score: 64.3142 bits (155), Expect = 2.366e-10 Identity = 42/126 (33.33%), Postives = 55/126 (43.65%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDED----PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQ----NCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C N C+ N++ CD N C D SDE P C +C N+ L W+C+G DC + +DEQ C + + C + IP Y CD I CS G DETGCT+
Sbjct: 1293 CANRRCVYNSQRCDGQNDCGDWSDETGCSTPPIPTTCPADWVRCFYNSSGL----CISTSWLCNGRVDCPDAWDEQPAQCRTSPAPTRTCSPQEYQCDNGACIPSRYECDGRIQCSDGSDETGCTA 1414 HSP 6 Score: 50.447 bits (119), Expect = 3.573e-6 Identity = 41/144 (28.47%), Postives = 59/144 (40.97%), Query Frame = 3
Query: 1911 VSDICPPGYRFC---QNGECLENAKFCDKINHCADKSDEDPITCRE-------CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDG-FSLNNCGGKFFTCSDNKT-IPRGYVCDENIDCSQGEDETGCTSPQI 2306
+ CP + C +G C+ + C+ C D DE P CR C P +C+ N +P + + CDG C +G DE C S ++C G F C N +P CD + DC DE C+ P +
Sbjct: 1325 IPTTCPADWVRCFYNSSGLCISTSWLCNGRVDCPDAWDEQPAQCRTSPAPTRTCSPQEYQCD-NGACIPSR------YECDGRIQCSDGSDETGCTATISPSSCPG--FLCDGNTLCLPFYKRCDGSYDCKDYTDEFNCSMPLM 1459
BLAST of low density lipoprotein receptor-1 vs. Ensembl Nematostella
Match: EDO49498 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGB0]) HSP 1 Score: 73.1738 bits (178), Expect = 2.403e-13 Identity = 44/114 (38.60%), Postives = 59/114 (51.75%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSD-NKTIPRGYVCDENIDCSQGEDE 2282
C NG+C+ A CD + CADKSDE T + C P C + +K WICDGE DCG+ DE +C L +CG + CS+ ++ I + VCD +DC DE
Sbjct: 171 CSNGQCISLAWRCDGDHDCADKSDERNCTGKTCKPFEFACANGRHCIQRK------WICDGENDCGDRSDEVDC---GLESCGNDRWRCSNTSRCIAKSQVCDGRVDCPDASDE 275 HSP 2 Score: 68.5514 bits (166), Expect = 7.717e-12 Identity = 46/129 (35.66%), Postives = 60/129 (46.51%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPIT-CRE--CDPISRKCEINNQILPKKNYFLIHWICDGEEDC--GNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
C G C+NG C+ CD N C D SDED C E C +C+ + + +P + W CDG+ DC + DE NC NC F C++ + PR +VCD DC G DE GC
Sbjct: 1 CSAGKFTCKNGHCISLRWKCDGENDCVDNSDEDEYAGCAEWSCRASEFRCQASRKCIP------LSWRCDGDYDCLAPDLSDEANCS--VATNCSASMFRCANGQCKPRDWVCDGFDDCGDGSDEKGCA 121 HSP 3 Score: 65.0846 bits (157), Expect = 9.338e-11 Identity = 41/128 (32.03%), Postives = 54/128 (42.19%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
V+ C C NG+C CD + C D SDE C P C P + W CDG+ DC +G DE+ C NC F+CS+ + I + CD + DC+ DE CT
Sbjct: 82 VATNCSASMFRCANGQCKPRDWVCDGFDDCGDGSDEKGCANHSCTPAQFSC-------PSGRCIPLRWRCDGDGDCSDGADERGC---PPKNCTDSQFSCSNGQCISLAWRCDGDHDCADKSDERNCT 199
BLAST of low density lipoprotein receptor-1 vs. Ensembl Nematostella
Match: EDO45747 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS53]) HSP 1 Score: 63.5438 bits (153), Expect = 3.721e-12 Identity = 43/116 (37.07%), Postives = 52/116 (44.83%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG C+ CD N C D SDE + R C P +C P W+CDGE DC G DE++C + + C F C IPR VCD DC Q +DE C
Sbjct: 7 CDNGRCISATWVCDTENDCGDNSDEMNCSQRSCSPDEYQC-------PNGECIRKRWVCDGEPDCEGGADEKDC---ANSKCKESQFRCMGGVCIPRDLVCDGFPDCKQKDDEDNC 112
BLAST of low density lipoprotein receptor-1 vs. Ensembl Nematostella
Match: EDO43938 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXB8]) HSP 1 Score: 68.1662 bits (165), Expect = 8.738e-12 Identity = 45/118 (38.14%), Postives = 56/118 (47.46%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIH--WICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C+NG C+ CD ++ C D SDED R P KC N ++ N +H WICDGE DC +G DE C C FTC++ K IP CD +C G DE C
Sbjct: 128 CRNGRCVLKEWLCDGMDDCGDSSDEDNCLTRP-TPPPVKCRKNERMCADGN-GCVHRRWICDGERDCLDGSDEAGCGTIG---CSSDEFTCTNQKCIPLPQKCDGTDNCGDGSDEKMC 240 HSP 2 Score: 52.7582 bits (125), Expect = 6.148e-7 Identity = 41/133 (30.83%), Postives = 57/133 (42.86%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQ-NGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCE-INNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLN---NCGGKFFTCSD-NKTIPRGYVCDENIDCSQGEDETGC 2291
V+ C P C +G C+ CD + C D SDE + C ++ C + + L W+CDG +DCG+ DE NC C C+D N + R ++CD DC G DE GC
Sbjct: 74 VNKTCAPYEFTCAFSGRCIPGRFRCDHRSDCLDGSDE-----QNCQNAAKTCNPVTDHTCRNGRCVLKEWLCDGMDDCGDSSDEDNCLTRPTPPPVKCRKNERMCADGNGCVHRRWICDGERDCLDGSDEAGC 201 HSP 3 Score: 51.2174 bits (121), Expect = 1.588e-6 Identity = 41/125 (32.80%), Postives = 52/125 (41.60%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDE-DPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCS-DNKTIPRGYVCDENIDCSQGEDETGC 2291
CPP C N +C+ N+ CD N C D+SDE +P T C N + CD E DC + DE+ C C FTC+ + IP + CD DC G DE C
Sbjct: 1 CPPSDFTCANSQCVPNSFRCDGENDCGDRSDESEPTT---------TCSANEFRCDDGRCITSTFRCDREFDCTDRSDERGCVN---KTCAPYEFTCAFSGRCIPGRFRCDHRSDCLDGSDEQNC 113
BLAST of low density lipoprotein receptor-1 vs. Ensembl Nematostella
Match: EDO43726 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXU8]) HSP 1 Score: 68.1662 bits (165), Expect = 1.098e-11 Identity = 50/171 (29.24%), Postives = 68/171 (39.77%), Query Frame = 3
Query: 1911 VSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC----------------RECDPISRKCEINN--------------QILPKK-----------NYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
V C C NG+C+ N+ CD N C D SDE C R+C P KC+ +N + P++ L HW CDGE+DC +G DE+ C +NC FTC++ + IP CD +C DE C +P
Sbjct: 116 VQRTCASNQFTCSNGDCISNSWTCDGDNDCNDGSDEKESLCASKSCKITEFTCRTSRRKCIPSQWKCDGDNDCPDSSDESGCPTASVSPRRCSVGMFKCRNGECVLGHWRCDGEKDCSDGSDEKGC---RKSNCASSEFTCANGQCIPSSQRCDGTSNCRDSSDEKACVTP 283 HSP 2 Score: 57.3806 bits (137), Expect = 1.985e-8 Identity = 46/157 (29.30%), Postives = 63/157 (40.13%), Query Frame = 3
Query: 1890 QVSSKIYVSDICPPGYR----------------FCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC--SDNKTIPRGYVCDENIDCSQGEDETGCTSPQI 2306
Q + K D C GYR C N +C+ + CD + C D SDED + R C N + W CDG+ DC +G DE+ + +C FTC S K IP + CD + DC DE+GC + +
Sbjct: 54 QATWKCDGEDDCRDGYRSDESNCGNVTCGADEFMCSNRKCISRSWTCDNQDDCGDNSDEDR-------NVQRTCASNQFTCSNGDCISNSWTCDGDNDCNDGSDEKE-SLCASKSCKITEFTCRTSRRKCIPSQWKCDGDNDCPDSSDESGCPTASV 202 HSP 3 Score: 52.7582 bits (125), Expect = 5.806e-7 Identity = 38/106 (35.85%), Postives = 49/106 (46.23%), Query Frame = 3
Query: 1980 CDKINHCADKSDED--PITCRECDPISRKCEINNQILPKKNYFL-IHWICDGEEDCGNGY--DEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE 2282
CD + C+D SDE P TC + +Q + + W CDGE+DC +GY DE NC + CG F CS+ K I R + CD DC DE
Sbjct: 21 CDGEDDCSDGSDEQGSPKTC-----------LQDQFTCRNGKCIQATWKCDGEDDCRDGYRSDESNCGNVT---CGADEFMCSNRKCISRSWTCDNQDDCGDNSDE 112
BLAST of low density lipoprotein receptor-1 vs. Ensembl Medaka
Match: hspg2 (heparan sulfate proteoglycan 2 [Source:NCBI gene;Acc:101159991]) HSP 1 Score: 127.102 bits (318), Expect = 3.653e-29 Identity = 78/208 (37.50%), Postives = 99/208 (47.60%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSF 2564
CQ+GEC+ CD CAD SDE T C+P +C+ L W CDG+ DC + DE +C C K F C SD K IP Y CDE DC+ DE GC P +T + A + V TC A G P P++ WR NWG I S R S N + +LTI+D K D G Y CEA++++ F
Sbjct: 190 CQSGECISRDYICDGERDCADGSDEFRCTPSPCEPNEFRCK-------NGRCALKLWRCDGDNDCEDNSDEMDCTKGPEEQCASKHFECVSDRKCIPASYQCDEEPDCADRSDEYGC-PPTVTTPPEESIQAVRGSTVMFTCRAVGVPTPMITWRLNWGHIPVSGRVSMNN-----KNGFGTLTIRDVKESDQGAYTCEAINAKGLVF 384 HSP 2 Score: 66.2402 bits (160), Expect = 1.592e-10 Identity = 103/465 (22.15%), Postives = 176/465 (37.85%), Query Frame = 3
Query: 354 ANRYLYIKSLLKQDEGIYNCSVEKVKD-PQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKD-------EFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVH-RGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRL-DGQYVSMLVISDISQINEGNYECRVGSSIKEVN----LIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFS 1706
+N L I +D G Y C+ + + + +P+ + PE + + ++ Q L P + + L ++K + + L++P V G YIC + T EA +++ ++ Y N R GE L+C + + + W K D E G D L I ++ G+YKCVAS ++ S + AF + + L + PQV V RG E C +++G + W G G +P + + DG ++I ++ Q NEG Y CR S E L + L + +I + V G SVEF C+ P +KW+ V ++P I + + + + D+G Y CT N + +V+ + + P + V G + C +
Sbjct: 2096 SNALLQILVARPEDSGTYVCTAQNSNGLSETNVEVIVQGGPLVPTAPMVTAPEPFMVV---VEGQSVTLHFPSPLMSWSKLRSPLPWRHKLVNGS--LELPSVGRQDSGEYIC--SGRNTMGTSEATIMLDV-EAPPYTTST-QNDVAVRVGEVIRLQC-LAHGTPPLTFVWTKVDGQLPPRAEVDGGD--LQINLATAEDAGSYKCVASNKVGSSE-----------AFVKVTVRPLAVRVSPQVEVKARGGTVEFTC---SAAGGVETKIRWLKEG-----GALPPNHHIKDG-----VLIENLEQSNEGVYICRASSVYGEAQDTARLTIQLPKVMINVRTSVQTVMIGTSVEFECQAVGDP---EPTIKWS------KVDGSLP--------AHIVVKGGMLKIERVTEVDAGQYRCTATNNVGSVQSQVVL-NVQLPQIATLPEKKEVTVGSDAVLPCVA 2506 HSP 3 Score: 57.7658 bits (138), Expect = 5.680e-8 Identity = 92/387 (23.77%), Postives = 157/387 (40.57%), Query Frame = 3
Query: 675 GRYICQYK-SKETSKIYEAATYVNLKQSVSYKIKIIT---NPALFRYGERFSLRCEVEPFYQNIKYTWYKKD-------EFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSS--IKEVNLIVLLDEG-LIETSP------PILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGR 1775
G YIC+ + S S ++A+ V++ S + II + A G+ S RC+V + +K W + + + L I + +++N G Y+C+AS L + +SI + + +T QV V G+ L C+ + G W+ + N L + L + ++L I + G Y C +S + E N+ V++ G L+ T+P P + V EGQSV H PS + W+ +R+ +P R +L+N + L DSG YIC+ N I++ + T T ++ VR G+ + ++C A G P +F K G+
Sbjct: 1921 GEYICRVEGSPGNSHFHQASVSVSVTSPSSLQSPIIAIEPHSAAVEEGKSTSFRCKVYGGAEPVKLEWKMANNQPLPNAKVSPDGSVLTITNARRENYGPYRCIAS------NLFGVTQSIVSL-IVKSPVVTVTPVGPVQVRV--GDPITLECQ---AGGEPHPSVSWH---RLDNNRKTMLKSPLPMESNALLQILVARPEDSGTYVCTAQNSNGLSETNVEVIVQGGPLVPTAPMVTAPEPFMVVVEGQSVTLH-----FPSPL---MSWS------KLRSPLP-WRHKLVNGSLE-------LPSVGRQDSGEYICSGRNTMGTSEATIMLDVEAPPYTTSTQNDVAVRVGEVIRLQCL-------AHGTPPLTFVWTKVDGQ 2263 HSP 4 Score: 57.7658 bits (138), Expect = 6.394e-8 Identity = 93/460 (20.22%), Postives = 169/460 (36.74%), Query Frame = 3
Query: 246 IVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNI----LQIPVVDESVVGRYICQYKSK-ETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQEL----VIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGL--IETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQ 1592
+V+ + ++ + +++ + + W K N L + S+ +QD G Y CS T+ L + P + + ++++G I+ QC G P T+ W + + LQI + G Y C +K +S+ + T L VS ++++ G C + K W K+ + + + +I++ ++ N G Y C AS + D +IQ + + T V G E C+ + G+ +W +G +P + G ML I +++++ G Y C +++ V V+L+ L I T P +V G C P+ N+KW+ +E +P +Q N + + + DSG YICT N Q
Sbjct: 2153 VVEGQSVTLHFPSPLMSWSKLRSPLPWRHK-----LVNGSLELPSVGRQDSGEYICSGRNTMGTS---EATIMLDVEAPPYTTSTQNDVAVRVGEVIRLQCLAHGTP------PLTFVWTKVDGQLPPRAEVDGGDLQINLATAEDAGSYKCVASNKVGSSEAFVKVTVRPLAVRVSPQVEVKAR------GGTVEFTCSAAGGVET-KIRWLKEGGALPPNHHIKDGVLIENLEQSNEGVYICRASSVYGEAQ-DTARLTIQLPKVMINVRTSVQT-------VMIGTSVEFECQ---AVGDPEPTIKW-----SKVDGSLPAHIVVKG---GMLKIERVTEVDAGQYRCTATNNVGSVQSQVVLNVQLPQIATLPEKKEVTVGSDAVLPCVASGYPA---PNIKWSKMEEE------LPSKCFQEAN--------VLTVPQVTHEDSGTYICTASNKQ 2555
BLAST of low density lipoprotein receptor-1 vs. Ensembl Medaka
Match: lrp2b (low density lipoprotein receptor-related protein 2b [Source:ZFIN;Acc:ZDB-GENE-111115-1]) HSP 1 Score: 82.4185 bits (202), Expect = 1.578e-15 Identity = 44/118 (37.29%), Postives = 62/118 (52.54%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C G C N+ CD I C DK+DE C C P++ C NN K+ W CDG +DCG+G DE NC + + C ++FTC + + + + ++CD + DC G DE C S
Sbjct: 56 CDEGRCRPNSYRCDGIFDCVDKTDE--ANCTSCSPLAFTC--NN-----KHCIYSSWRCDGMDDCGDGSDEVNCPTYIPSTCSSEYFTCDNKRCVSKAWLCDGDNDCGDGSDERNCNS 164 HSP 2 Score: 72.4034 bits (176), Expect = 2.099e-12 Identity = 43/123 (34.96%), Postives = 62/123 (50.41%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C P C N C+ ++ CD ++ C D SDE + C P + C K W+CDG+ DCG+G DE+NC+ S++ C +F C D++ I +VCD + DC G DE C
Sbjct: 86 CSPLAFTCNNKHCIYSSWRCDGMDDCGDGSDE--VNCPTYIPST--CSSEYFTCDNKRCVSKAWLCDGDNDCGDGSDERNCNS-SISTCRPGYFLCPDHRCISSYFVCDGDQDCLDGSDEKNC 203 HSP 3 Score: 66.6254 bits (161), Expect = 1.076e-10 Identity = 44/135 (32.59%), Postives = 61/135 (45.19%), Query Frame = 3
Query: 1890 QVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTC-SDNKTIPRGYVCDENIDCSQGEDETGC 2291
+V+ Y+ C Y C N C+ A CD N C D SDE R C+ C + P +++CDG++DC +G DE+NC+ FS C F C S ++ + Y CD DC DE C
Sbjct: 117 EVNCPTYIPSTCSSEYFTCDNKRCVSKAWLCDGDNDCGDGSDE-----RNCNSSISTCRPGYFLCPDHRCISSYFVCDGDQDCLDGSDEKNCE-FS---CQSYQFACASGDQCVSSSYRCDGVFDCRDHSDERNC 242 HSP 4 Score: 59.6918 bits (143), Expect = 1.341e-8 Identity = 39/125 (31.20%), Postives = 60/125 (48.00%), Query Frame = 3
Query: 1935 YRF-CQNG-ECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQN-CDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
Y+F C +G +C+ ++ CD + C D SDE C +C+++ +P +W CDG DC +G DE N C + C +F C++ IP ++CD DC DE C +P
Sbjct: 210 YQFACASGDQCVSSSYRCDGVFDCRDHSDERNCRPGLCHDDEFQCQMDGFCIPA------NWECDGHPDCEDGSDEHNTCPAVT---CLSSYFQCANKMCIPMSWLCDGENDCRDMSDEQNCPTP 325
BLAST of low density lipoprotein receptor-1 vs. Ensembl Medaka
Match: ldlrb (low-density lipoprotein receptor [Source:NCBI gene;Acc:101161779]) HSP 1 Score: 77.7962 bits (190), Expect = 3.097e-14 Identity = 47/122 (38.52%), Postives = 62/122 (50.82%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC--RECDPISRKCEIN-NQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C NG C+ CD + C D +DE TC + C P C NQ +PK W CDG+ DC NG DE+NC ++ C F C++ + I +VCD + DCS G DET C+ P
Sbjct: 37 CGNGRCVTRRWICDGTDDCGDGTDELLSTCASKTCLPSQFNCGAPINQCVPKS------WHCDGKADCSNGADEKNC---TVKQCKNDEFRCANGQCISLSFVCDNDNDCSDGSDETTCSKP 149 HSP 2 Score: 71.633 bits (174), Expect = 2.735e-12 Identity = 44/122 (36.07%), Postives = 62/122 (50.82%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE--QNCDGFS-LNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C NG+C+ + CD N C+D SDE + C+P+S +C N+ +P W CDG+EDC +G DE + C G C F C++ + IP + CD IDC DE C+ P
Sbjct: 119 CANGQCISLSFVCDNDNDCSDGSDETTCSKPTCNPLSFQCN-NSVCVPSL------WRCDGDEDCADGSDEWPETCGGKKPAAKCSVSEFECANGQCIPGSWRCDGGIDCDDRSDELNCSRP 233 HSP 3 Score: 55.4546 bits (132), Expect = 2.347e-7 Identity = 46/131 (35.11%), Postives = 56/131 (42.75%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEI------NNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTS 2297
C P C N C+ + CD CAD SDE P TC P + KC + N Q +P W CDG DC + DE NC S C F C D + C+ DCS G DET C++
Sbjct: 151 CNPLSFQCNNSVCVPSLWRCDGDEDCADGSDEWPETCGGKKPAA-KCSVSEFECANGQCIPGS------WRCDGGIDCDDRSDELNC---SRPVCLEGQFQCGDGSCLQGNLKCNSVRDCSDGSDETDCST 271 HSP 4 Score: 50.447 bits (119), Expect = 9.470e-6 Identity = 29/72 (40.28%), Postives = 36/72 (50.00%), Query Frame = 3
Query: 2109 HWICDGEEDCGNGYDEQNCDGFSLNNCGGKF-----FTCSD--NKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
WICDG +DCG+G DE L+ C K F C N+ +P+ + CD DCS G DE CT Q
Sbjct: 46 RWICDGTDDCGDGTDEL------LSTCASKTCLPSQFNCGAPINQCVPKSWHCDGKADCSNGADEKNCTVKQ 111
BLAST of low density lipoprotein receptor-1 vs. Ensembl Medaka
Match: lrp2a (LDL receptor related protein 2 [Source:NCBI gene;Acc:101157655]) HSP 1 Score: 74.7146 bits (182), Expect = 3.653e-13 Identity = 49/128 (38.28%), Postives = 59/128 (46.09%), Query Frame = 3
Query: 1923 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDE-QNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQ 2303
C G C G C+ CD + C D SDE CD +C + + +P W+CD EEDC +G DE QNC G C G FTCS+ IP Y CD DCS G DE C P+
Sbjct: 5 CELGQFRCGTGRCIPGDWHCDGTSDCVDDSDEQDCPQVTCDHSHFQCLSDGECIPDV------WVCDDEEDCEDGSDERQNCPG---RTCTGDQFTCSNGMCIPALYRCDHMADCSDGSDERHCNYPE 123 HSP 2 Score: 67.781 bits (164), Expect = 4.675e-11 Identity = 42/120 (35.00%), Postives = 60/120 (50.00%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITC----RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG+C+ N+ CD ++ C D SDE ++C C P + C N + +P + W CDG DC + DE NC C FTC++++ IP + CD + DC G DE C
Sbjct: 799 CGNGKCVPNSYRCDGVDDCHDNSDE--MSCGVNSTTCSPSAFTCA-NRRCVP------VGWRCDGHNDCLDDSDEINCPTRVPGTCPANQFTCANHRCIPHTWRCDTDNDCGDGSDEVDC 909 HSP 3 Score: 64.3142 bits (155), Expect = 5.897e-10 Identity = 39/116 (33.62%), Postives = 60/116 (51.72%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C NG C + + CD + C D SDE T + C+ +C+ N +P++ ++CD ++DCG+ DE NC + C G +FTC + I + ++CD DC DE GC
Sbjct: 129 CTNGACYDRTQRCDHVLDCRDGSDEANCT-QHCNAGMFQCQ-NGLCIPQR------YVCDHDDDCGDRSDELNC---TYPTCKGNYFTCPSGRCIHQVWLCDGEDDCEDNADEKGC 233 HSP 4 Score: 62.003 bits (149), Expect = 2.358e-9 Identity = 53/175 (30.29%), Postives = 75/175 (42.86%), Query Frame = 3
Query: 1872 CSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRE-CDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSD-NKTIPRGYVCDENIDCSQGEDETGCTS--PQIXXXXXXXXXXXXXQLVTLTCEATGKP 2384
C + +++ V CP C N C+ + CD N C D SDE + CR C+P +C + I P +ICDG+ DC +G DEQ+C NC F C++ ++ I Y CD DCS DE C + P + + + V T E G P
Sbjct: 858 CLDDSDEINCPTRVPGTCPANQFTCANHRCIPHTWRCDTDNDCGDGSDE--VDCRNTCNPEQFQCPDHRCIDPN-------YICDGDRDCVDGADEQDCS----YNCTANEFKCTNGHQCISSYYHCDGVFDCSDRSDEHNCPTRPPGMCHHESEFQCQSDGSCVPSTWECDGHP 1019 HSP 5 Score: 62.003 bits (149), Expect = 2.967e-9 Identity = 45/133 (33.83%), Postives = 60/133 (45.11%), Query Frame = 3
Query: 1914 SDICPPGYRFCQNGECLENAKFCDKINHCADKSDE------DPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
S C P C N C+ CD N C D SDE P TC P ++ N++ +P W CD + DCG+G DE +C N C + F C D++ I Y+CD + DC G DE C+
Sbjct: 830 STTCSPSAFTCANRRCVPVGWRCDGHNDCLDDSDEINCPTRVPGTC----PANQFTCANHRCIPHT------WRCDTDNDCGDGSDEVDC----RNTCNPEQFQCPDHRCIDPNYICDGDRDCVDGADEQDCS 948 HSP 6 Score: 55.4546 bits (132), Expect = 2.920e-7 Identity = 40/119 (33.61%), Postives = 51/119 (42.86%), Query Frame = 3
Query: 1944 CQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C NG C+ CD + C+D SDE EC + +C N + CD DC +G DE NC +C F C + IP+ YVCD + DC DE CT P
Sbjct: 92 CSNGMCIPALYRCDHMADCSDGSDERHCNYPECTQL--RC-TNGACYDRTQR------CDHVLDCRDGSDEANC----TQHCNAGMFQCQNGLCIPQRYVCDHDDDCGDRSDELNCTYP 197 HSP 7 Score: 53.1434 bits (126), Expect = 1.570e-6 Identity = 37/124 (29.84%), Postives = 55/124 (44.35%), Query Frame = 3
Query: 1944 CQNG-ECLENAKFCDKINHCADKSDEDPITCRE---CDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSP 2300
C NG +C+ + CD + C+D+SDE R C S +C+ + +P W CDG DC +G DE + C F C + + R ++CD + DC DE C +P
Sbjct: 958 CTNGHQCISSYYHCDGVFDCSDRSDEHNCPTRPPGMCHHESEFQCQSDGSCVPST------WECDGHPDCEDGSDEHH--ACPPRTCSSSLFRCDNGNCVLRSWICDGDNDCRDMSDERDCPTP 1073
BLAST of low density lipoprotein receptor-1 vs. Ensembl Medaka
Match: sorl1 (sortilin related receptor 1 [Source:NCBI gene;Acc:101160573]) HSP 1 Score: 74.3294 bits (181), Expect = 5.656e-13 Identity = 51/170 (30.00%), Postives = 78/170 (45.88%), Query Frame = 3
Query: 1806 PAHKRL-TAPGGL---SLSDNNMDVFCSLEGRQVSSK--IYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISR-KCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCT 2294
P HK P G+ ++ + + C G Q+ +K + C P C+NG C+ + CD N C D SDE CDP + +C + +P + + CD E+DCG+ DE+ C+ + CG FTC+ I ++CD + DC DE+ CT
Sbjct: 931 PGHKHTCVCPDGVPMVTMPEGELQCKCPF-GYQLRNKTCVKTERTCLPNQYHCRNGRCISSIWKCDSDNDCGDMSDEQECPTTTCDPSHQFRCMASGSCIP------LAFKCDHEDDCGDNSDEEQCEA---HQCGPGEFTCARGVCIREAWLCDGDNDCRDWSDESNCT 1090 HSP 2 Score: 58.151 bits (139), Expect = 4.209e-8 Identity = 41/127 (32.28%), Postives = 56/127 (44.09%), Query Frame = 3
Query: 1944 CQN-GECLENAKFCDKINHCADKSDEDPITC--------RECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFT--CSDNKTIPRGYVCDENIDCSQGEDETGC 2291
C+N +CL + CD I HC D SDED + CD + +C N + + W CDG +DCG+ DE NC + +FF C + + IP + CD DC DE C
Sbjct: 1181 CRNRAQCLFQSLVCDGIKHCEDGSDEDAAYAGSTPSEFGKVCDAYTFQCA--NGVCVS-----LEWKCDGMDDCGDYSDEANCAAPTEAPGCSRFFQYECRNGRCIPTWWKCDGENDCGDWSDEALC 1300 HSP 3 Score: 55.8398 bits (133), Expect = 2.230e-7 Identity = 43/132 (32.58%), Postives = 53/132 (40.15%), Query Frame = 3
Query: 1932 GYRF-CQNGECLENAKFCDKINHCADKSDED----PITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNN-------CGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGC 2291
Y F C NG C+ CD ++ C D SDE P C + N + +P W CDGE DCG+ DE C G + + C F C I +VCD DC G DE GC
Sbjct: 1224 AYTFQCANGVCVSLEWKCDGMDDCGDYSDEANCAAPTEAPGCSRFFQYECRNGRCIP------TWWKCDGENDCGDWSDEALC-GVTPHTVTPGPTTCASNRFHCGSGACIINTWVCDGYADCRDGSDELGC 1348
BLAST of low density lipoprotein receptor-1 vs. Planmine SMEST
Match: SMESG000027815.1 (SMESG000027815.1) HSP 1 Score: 1645.56 bits (4260), Expect = 0.000e+0 Identity = 814/825 (98.67%), Postives = 817/825 (99.03%), Query Frame = 3
Query: 123 LICIYQSLVKAETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 2597
++ I S +TEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCN VTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN
Sbjct: 1 MLIISPSFCIRKTEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNFVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 825
BLAST of low density lipoprotein receptor-1 vs. Planmine SMEST
Match: SMESG000027815.1 (SMESG000027815.1) HSP 1 Score: 1644.02 bits (4256), Expect = 0.000e+0 Identity = 813/814 (99.88%), Postives = 813/814 (99.88%), Query Frame = 3
Query: 156 ETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 2597
ETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCN VTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN
Sbjct: 16 ETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNFVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 829
BLAST of low density lipoprotein receptor-1 vs. Planmine SMEST
Match: SMESG000027815.1 (SMESG000027815.1) HSP 1 Score: 1633.23 bits (4228), Expect = 0.000e+0 Identity = 810/825 (98.18%), Postives = 814/825 (98.67%), Query Frame = 3
Query: 123 LICIYQSLVKAETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 2597
++ I S +TEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRE +LTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCN VTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN
Sbjct: 1 MLIISPSFCIRKTEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRE---KLTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNFVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 822
BLAST of low density lipoprotein receptor-1 vs. Planmine SMEST
Match: SMESG000027815.1 (SMESG000027815.1) HSP 1 Score: 1631.69 bits (4224), Expect = 0.000e+0 Identity = 809/814 (99.39%), Postives = 810/814 (99.51%), Query Frame = 3
Query: 156 ETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 2597
ETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRE +LTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCN VTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN
Sbjct: 16 ETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRE---KLTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCRECDPISRKCEINNQILPKKNYFLIHWICDGEEDCGNGYDEQNCDGFSLNNCGGKFFTCSDNKTIPRGYVCDENIDCSQGEDETGCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNFVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 826
BLAST of low density lipoprotein receptor-1 vs. Planmine SMEST
Match: SMESG000027815.1 (SMESG000027815.1) HSP 1 Score: 1282.7 bits (3318), Expect = 0.000e+0 Identity = 627/637 (98.43%), Postives = 630/637 (98.90%), Query Frame = 3
Query: 123 LICIYQSLVKAETEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC 2033
++ I S +TEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC
Sbjct: 1 MLIISPSFCIRKTEEFTFGGASEEEETSPPNITFFPLKNDSIVKSEMQFINIACNVTNYALNETSIRWLDKDGKVAAANRYLYIKSLLKQDEGIYNCSVEKVKDPQIRFNRTLHLKITIPSISIDILPEESLKIGGQIKRQCSDLGLPQETIVDDFTYTWLNQQNKTIGNTNILQIPVVDESVVGRYICQYKSKETSKIYEAATYVNLKQSVSYKIKIITNPALFRYGERFSLRCEVEPFYQNIKYTWYKKDEFIGNDQELVIKSFKKDNVGTYKCVASLQLPSGKLDLMEESIQQFAFFRESKIELTTKPGPQVYVHRGEKKELHCEIETSSGNRGKEAEWYINGKKFKNGDIPLVNRLDGQYVSMLVISDISQINEGNYECRVGSSIKEVNLIVLLDEGLIETSPPILKVKEGQSVEFHCRVENIPSVKNVNLKWNFESKEGLVRNNIPDSRWQLMNDEIADQTSFIVLMKAEVSDSGYYICTEPNGQTARSELIVIPDKDKNSLTITPREIRVRAGQRVDIECFSKNTQGRASGNPEFSFTNNKPIGRDGRFKISNVGPAHKRLTAPGGLSLSDNNMDVFCSLEGRQVSSKIYVSDICPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITC 637 HSP 2 Score: 192.2 bits (487), Expect = 6.233e-51 Identity = 109/139 (78.42%), Postives = 115/139 (82.73%), Query Frame = 3
Query: 2187 CGGKFFTCSDNKTIPRGYVCDENIDCSQGEDE--TGCTSPQIXXXXXXXXXXXXXQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNSVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 2597
C + C + + + CD+ C+ DE CTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCN VTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN
Sbjct: 601 CPPGYRFCQNGECLENAKFCDKINHCADKSDEDPITCTSPQITKTSATKVVATKSQLVTLTCEATGKPLPVLVWRFNWGCIQNSTRFSTNFFSTDCNFVTSSLTIKDFKAGDDGIYNCEALSSRQRSFSNDFQVILKNN 739 The following BLAST results are available for this feature:
BLAST of low density lipoprotein receptor-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of low density lipoprotein receptor-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of low density lipoprotein receptor-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015642 ID=SMED30015642|Name=low density lipoprotein receptor-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2673bpback to top protein sequence of SMED30015642-orf-1 >SMED30015642-orf-1 ID=SMED30015642-orf-1|Name=SMED30015642-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=835bp MISICKIFALICIYQSLVKAETEEFTFGGASEEEETSPPNITFFPLKNDSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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