Innexin

Overview
NameInnexin
Smed IDSMED30015595
Length (bp)1709
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30015595) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30015595) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30015595) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30015595) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30015595

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 22

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymaSMED30015595h1SMcG0001481 AY066375smed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30015595h1SMcG0001481 AY066375smed_ncbi_20240424PMID:17670787
Oviedo et al., 2007		whole organism asexual adult colorimetric in situ hybridization evidence
Smed sexual biotypeSMED30015595h1SMcG0001481 Contig39933uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015595h1SMcG0001481 Contig39933newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015595h1SMcG0001481 Contig39933uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015595h1SMcG0001481 Contig39933newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30015595h1SMcG0001481 dd_Smed_v4_3879_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887])

HSP 1 Score: 263.462 bits (672), Expect = 1.345e-82
Identity = 138/362 (38.12%), Postives = 208/362 (57.46%), Query Frame = 1 
Query:  340 GDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRN----SKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERD---CGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNY 1404
            GD  S ID LNY ++  +LV+F   +  +QY+G+PIQCW+P +FT AWE Y+EN C+VQNTYF+ P+K +PDS+++   AE I YYQW+  ++G QA+L YLP + WR+ +    V L+     +K+A   D + R +A     A L E      RF K  S           G+ L+ L++ V+FL++   + Q  ++ +FLGT++T +G+ I  DIL G +W+ SGHFPRVT C  E+R +G      +T+QCVL IN F EK+Y FLWFW V +  AT  N + W   L  ++ +   + +YL+     S    R+     +FV+  L +DG+F+   + N    + + DV   MW  +
Sbjct:   15 GDDDS-IDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGAWEQYSENYCFVQNTYFISPDKYIPDSEIDREGAE-IGYYQWVPFILGLQAILFYLPSLFWRLMNFNSGVALKKMLFGAKKADRVDEKARNEAAKSTGAHLYESLTLQSRFAKYTSAF------TYGGSYLTYLYLFVKFLYLVQIVFQFIILNNFLGTSYTFWGLGILSDILNGREWEESGHFPRVTMCDFEVRVLGN--KHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRF 366
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393])

HSP 1 Score: 258.84 bits (660), Expect = 8.376e-81
Identity = 136/359 (37.88%), Postives = 205/359 (57.10%), Query Frame = 1 
Query:  358 IDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPV----LLRNSKEAILPDRELRRKAVACLVAALEE------QAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNY 1404
            ID LNY Y++A++ VF  ++  +QY+G PIQCWVP  FT   E Y EN CWVQNTYFLP    +P +  E  + + I YYQW+  V+  +A+L Y+P I+WR+ S +  +    L++ + ++ L D E R +A+  +   +EE      Q +   R +  N  I    C    GA ++ L++ V+ L+  N +GQ++L+  FLG     +G+ +  D++ G +W+ SGHFPRVT C  E++ +G +    +T+QCVL IN F EKI+ FLWFW+  LA AT  +   W     V +RQ+ FV  YL  ++     + +   RFV   L  DG+FLLR VA  A +L   ++   +W NY
Sbjct:   24 IDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQ-IGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLII----CTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHR--HTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 248.825 bits (634), Expect = 5.874e-77
Identity = 126/371 (33.96%), Postives = 209/371 (56.33%), Query Frame = 1 
Query:  310 LGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWR-----VGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYK 1407
            L  IF+         F+D LNY Y+SA++  F  I+  +QY+G PIQCWVP +FT AWE Y EN CWV+NTY+LP   A P  +     A  ISYYQW+  V+  +A+  Y+P I+WR             L + + +A + D + R   V  +   +E+        ++  + +  +         +++L++ ++ L++GN + Q++++  FLGT++  +G  I +D+L G +W+VSG+FPRVT C  E+R +G +    +T+QCVL IN F EKI+ FLWFW+  +A  ++ +   W I  F+  + + F+  YL+A     +T+ +   +FV   LG DG+F +R ++  A D++A ++   +W N+ 
Sbjct:    6 LAAIFKGLHPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFP-LEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDA----LEIQREVTDVSGMCVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHH--HTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL--ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFN 367
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 248.825 bits (634), Expect = 5.874e-77
Identity = 126/371 (33.96%), Postives = 209/371 (56.33%), Query Frame = 1 
Query:  310 LGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWR-----VGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYK 1407
            L  IF+         F+D LNY Y+SA++  F  I+  +QY+G PIQCWVP +FT AWE Y EN CWV+NTY+LP   A P  +     A  ISYYQW+  V+  +A+  Y+P I+WR             L + + +A + D + R   V  +   +E+        ++  + +  +         +++L++ ++ L++GN + Q++++  FLGT++  +G  I +D+L G +W+VSG+FPRVT C  E+R +G +    +T+QCVL IN F EKI+ FLWFW+  +A  ++ +   W I  F+  + + F+  YL+A     +T+ +   +FV   LG DG+F +R ++  A D++A ++   +W N+ 
Sbjct:    6 LAAIFKGLHPRVDDDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFP-LEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDA----LEIQREVTDVSGMCVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHH--HTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL--ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFN 367
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 247.669 bits (631), Expect = 6.537e-76
Identity = 123/357 (34.45%), Postives = 205/357 (57.42%), Query Frame = 1 
Query:  352 SFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWR-----VGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYK 1407
             F+D LNY Y+SA++  F  I+  +QY+G PIQCWVP +FT AWE Y EN CWV+NTY+LP   A P  +     A  ISYYQW+  V+  +A+  Y+P I+WR             L + + +A + D + R   V  +   +E+        ++  + +  +         +++L++ ++ L++GN + Q++++  FLGT++  +G  I +D+L G +W+VSG+FPRVT C  E+R +G +    +T+QCVL IN F EKI+ FLWFW+  +A  ++ +   W I  F+  + + F+  YL+A     +T+ +   +FV   LG DG+F +R ++  A D++A ++   +W N+ 
Sbjct:   20 DFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDAWEQYTENYCWVENTYYLPLTSAFP-LEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDA----LEIQREVTDVSGMCVQKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHH--HTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL--ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFN 367
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0112571)

HSP 1 Score: 92.0485 bits (227), Expect = 9.025e-20
Identity = 75/276 (27.17%), Postives = 120/276 (43.48%), Query Frame = 1 
Query:  367 LNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLP-----------PEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRV-GSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGH---FPRVTFCPV-EIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFW 1146
            L+Y  +  +L+ F  II TRQY+G PI C   ++     ED     CW+Q+TY L            P   + +SD +    +   YYQW+   +  QA+L Y P+ +W+     +   L+ +    I  + E ++K    L    E         R +N   Y+              + V   L + N IGQ++LM  F      TFG+ +   +    + ++      FPR+T C   +    G+++   +   C+LP+N   EKIY FLWFW
Sbjct:   26 LHYSITVMILMSFSLIITTRQYVGNPIDCVHTKDIP---EDVLNTYCWIQSTYTLKSLFLKKQGVSVPYPGIGNSDGDPADKKHYKYYQWVCFCLFFQAILFYTPRWLWKSWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWEN-------LRYHNWWAYR--------------YYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEK--HDAICILPLNVVNEKIYIFLWFW 275
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 90.8929 bits (224), Expect = 1.645e-19
Identity = 73/289 (25.26%), Postives = 123/289 (42.56%), Query Frame = 1 
Query:  367 LNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPE------KAVPDSDVELH-----SAEFISYYQWIVIVMGAQAVLCYLPQIIWRV-GSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGH---FPRVTFCPVEIRKMGQIKPA-IYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTL 1185
            ++Y+ +  +L+ F  ++ +RQYIG PI C V +      + Y    CW+ +T+ +P        + V    V  H       ++  YYQW+  V+  QA+L Y+P+ +W+     R  +L+ +    I+ D                      C+  +    +   +  L      +  F V   L   N IGQ+Y +  FL    +T+G  + +      D ++      FP+VT C     K G       +   CVLP+N   EKIY FLWFWF+ L+  +  + +
Sbjct:   26 MHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTY----CWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVNDE---------------------CKNDRKKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKC--TFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 90.8929 bits (224), Expect = 1.645e-19
Identity = 73/289 (25.26%), Postives = 123/289 (42.56%), Query Frame = 1 
Query:  367 LNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPE------KAVPDSDVELH-----SAEFISYYQWIVIVMGAQAVLCYLPQIIWRV-GSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGH---FPRVTFCPVEIRKMGQIKPA-IYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTL 1185
            ++Y+ +  +L+ F  ++ +RQYIG PI C V +      + Y    CW+ +T+ +P        + V    V  H       ++  YYQW+  V+  QA+L Y+P+ +W+     R  +L+ +    I+ D                      C+  +    +   +  L      +  F V   L   N IGQ+Y +  FL    +T+G  + +      D ++      FP+VT C     K G       +   CVLP+N   EKIY FLWFWF+ L+  +  + +
Sbjct:   26 MHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTY----CWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVNDE---------------------CKNDRKKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKC--TFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314)

HSP 1 Score: 90.8929 bits (224), Expect = 1.645e-19
Identity = 73/289 (25.26%), Postives = 123/289 (42.56%), Query Frame = 1 
Query:  367 LNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPE------KAVPDSDVELH-----SAEFISYYQWIVIVMGAQAVLCYLPQIIWRV-GSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGH---FPRVTFCPVEIRKMGQIKPA-IYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTL 1185
            ++Y+ +  +L+ F  ++ +RQYIG PI C V +      + Y    CW+ +T+ +P        + V    V  H       ++  YYQW+  V+  QA+L Y+P+ +W+     R  +L+ +    I+ D                      C+  +    +   +  L      +  F V   L   N IGQ+Y +  FL    +T+G  + +      D ++      FP+VT C     K G       +   CVLP+N   EKIY FLWFWF+ L+  +  + +
Sbjct:   26 MHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTY----CWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVNDE---------------------CKNDRKKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKC--TFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287
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BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006)

HSP 1 Score: 90.8929 bits (224), Expect = 1.645e-19
Identity = 73/289 (25.26%), Postives = 123/289 (42.56%), Query Frame = 1 
Query:  367 LNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPE------KAVPDSDVELH-----SAEFISYYQWIVIVMGAQAVLCYLPQIIWRV-GSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGH---FPRVTFCPVEIRKMGQIKPA-IYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTL 1185
            ++Y+ +  +L+ F  ++ +RQYIG PI C V +      + Y    CW+ +T+ +P        + V    V  H       ++  YYQW+  V+  QA+L Y+P+ +W+     R  +L+ +    I+ D                      C+  +    +   +  L      +  F V   L   N IGQ+Y +  FL    +T+G  + +      D ++      FP+VT C     K G       +   CVLP+N   EKIY FLWFWF+ L+  +  + +
Sbjct:   26 MHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGVMDTY----CWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHKYYQWVCFVLFFQAILFYVPRYLWKSWEGGRLKMLVMDLNSPIVNDE---------------------CKNDRKKILVDYFIGNLNRHNFYAFRFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKC--TFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLI 287
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 258.84 bits (660), Expect = 1.065e-79
Identity = 136/359 (37.88%), Postives = 205/359 (57.10%), Query Frame = 1 
Query:  358 IDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPV----LLRNSKEAILPDRELRRKAVACLVAALEE------QAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNY 1404
            ID LNY Y++A++ VF  ++  +QY+G PIQCWVP  FT   E Y EN CWVQNTYFLP    +P +  E  + + I YYQW+  V+  +A+L Y+P I+WR+ S +  +    L++ + ++ L D E R +A+  +   +EE      Q +   R +  N  I    C    GA ++ L++ V+ L+  N +GQ++L+  FLG     +G+ +  D++ G +W+ SGHFPRVT C  E++ +G +    +T+QCVL IN F EKI+ FLWFW+  LA AT  +   W     V +RQ+ FV  YL  ++     + +   RFV   L  DG+FLLR VA  A +L   ++   +W NY
Sbjct:   24 IDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTEPMEQYTENYCWVQNTYFLPLHDYIPHNYAERENRQ-IGYYQWVPFVLALEALLFYVPTIVWRLLSWQSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLII----CTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHR--HTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNY 375
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 233.417 bits (594), Expect = 1.749e-68
Identity = 122/388 (31.44%), Postives = 215/388 (55.41%), Query Frame = 1 
Query:  310 LGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWR-----VGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQA-IRNCRFRKNNSTIYKLL-----CGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERD---CGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTE 1431
            L   FR+        F+D LNY Y++ +L  F  ++  +QY+G PIQCWVP  FT A E Y EN CWVQNTY++P ++ +P  ++       I YYQW+  ++  +A+L Y+P I+WR             L++ + +A L D E++ + V  +   ++++  + N   + ++ + +  L     CG   G  +++L++ ++ L+  N + Q +L+   LG+N   +G  + +D++   +W+ +G FPRVT C  E+R +G I    +T+QCVL IN F EKI+ FLWFWF++    T  NT+ W + +F+ ++ + FV  YL+ L    +    D     +F    L  DG+F+LR ++  A +LM+ ++   +W+++ +   + T+
Sbjct:  126 LASAFRALYPRLDDDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENYCWVQNTYWVPMQEDIP-REIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHR--HTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFNNVDRSPTQ 510
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q27295|EAT5_CAEEL (Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN=eat-5 PE=2 SV=1)

HSP 1 Score: 210.305 bits (534), Expect = 9.164e-61
Identity = 118/371 (31.81%), Postives = 198/371 (53.37%), Query Frame = 1 
Query:  361 DVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPV----LLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKL-----LCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFV------EVVLGN--------DGIFLLRAVANVASDLMALDVTGIMWRNY 1404
            D LNY YS+ +++     I  RQY+G P+QCWVP +FT+AWE YAE+ C+V NTY++ P   VP +  E  S + I YYQW   +M  +A   YLP I W + S +  +    L+  +++A   + E R+K +  +   +      N R R+N     K+     + G+  G  ++ +++V + +++ N+  Q Y    FLG N   +G+ I  DIL G DW+ SG+FPR+  C  ++R +G ++   Y++QCVL +N F EKI+ FL+ WF+ +   T F+++    ++F  ++ V F+  +L    Q  + E++   R V       ++L          D I LL+ + N   D++  ++ G MW  +
Sbjct:   21 DRLNYYYSTLIIMGMSLTITARQYVGSPLQCWVPAQFTKAWEQYAEDYCFVYNTYWVKPNDKVPLTVEERVSQQLI-YYQWAPFIMAIEAAFFYLPVIFWSMLSTKSGINIIKLVETAQKAEGAESEERKKQIDIICRHIS----NNLRKRRNEEETTKMAKIQRIFGMQHGKYITNVYLVTKLIYMTNSFLQFYSTNKFLGQNDPYWGMRILDDILKGTDWEHSGNFPRIAMCDFQVRVLGNLQR--YSIQCVLTLNMFNEKIFLFLYIWFLLVFFVTLFDSIFLCYNMFSSHKLVEFLQQFLDNQDQDENDEKKPEERKVYRKEQHSILLSEFCLHKFTPDIIILLKMINNHTGDIVCTEIVGRMWNEF 384
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 208.764 bits (530), Expect = 2.881e-60
Identity = 119/369 (32.25%), Postives = 187/369 (50.68%), Query Frame = 1 
Query:  310 LGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRR----FPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNY 1404
            L   F+     D V   D L+Y  ++ +L  F  ++  +QY+G  IQCW+P EF   WE YAE+ C++QNT+F+P    +P  DVE      I YYQW+ IV+  QA + YLP  IW    ++    FP ++  ++     D E R K V  LV  + +  I + R +      Y    G G G+  S+L++ ++ +++ N   Q  ++  FLG     +G   F D+ AG +W+ SG FPRVT C   +RK+  +    YT+QCVL IN F EKIY F+WFWFV +   T  NTL     L   + +  ++ + L         E+     F    L  DG+ L+R + + A  ++  ++   +++ +
Sbjct:   11 LSETFKPKTFDDAV---DRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKGGWEQYAEDYCFIQNTFFIPERSEIP-GDVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYKQCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFIGD--ILDTRSKNEYGRFYCYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFADLYAGREWQDSGVFPRVTLCDFSVRKLANVHR--YTVQCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRSLLSGPVNNFKDEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKH 371
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BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q23157|INX11_CAEEL (Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=inx-11 PE=3 SV=1)

HSP 1 Score: 204.527 bits (519), Expect = 4.078e-58
Identity = 130/407 (31.94%), Postives = 203/407 (49.88%), Query Frame = 1 
Query:  328 SPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVP--DSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSR----RFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLG---PGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTN-HTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQL-------SSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNY----KHAKVTGT--EEDMAIVWLEAHTKIHK 1479
            SP   D  S  D LNY  +  +L+ F  +I  +Q+ G+PI+C  P +F  +WE YAEN CW Q+TYF+ P + V     +        +SYYQW+   +  QA     P  +W+  S     R   ++  +K++   + E+R K +  L   L           +    ++K +  L        +S +++  + L+  N   QLYLM  FLGTN H  +G  + QDI+ G  W+ SG+FPR   C  E+R++  I+   Y++QCVL IN F EKI+  LWFW+V L  +++ + +QWFI L        FV  +L AL  L       S  E+ D  +FV   L  DG+F+LR V++ A  + A D+   ++  Y    K+  V G+   +D+  +   A + I +
Sbjct:   15 SPREDDDWS--DRLNYLMTPNILLAFSVLISFKQFGGRPIECMFPNKFPGSWEQYAENYCWSQDTYFVEPTQDVSLLKKEERYTPDRQLSYYQWVPFFLLLQAAFFRAPSYLWKYFSNHSGIRIHEVVEKAKDSANVEEEVREKNILILKRHLSSALRFQANMERKKVQVHKTVTFLNFQYSSGFISWIYLFTKVLYFLNVFAQLYLMNYFLGTNRHHWYGFGVVQDIVQGEPWERSGYFPRAAVCDFEVRQVANIQR--YSVQCVLVINIFNEKIFVLLWFWYVILLLSSTVSLVQWFIVLVFPCFSKWFVKQHL-ALSTLQNFNQRNSRREDSDVSKFVTQYLHKDGVFVLRMVSSHAGIIFATDLVQALYEAYDFQDKNKDVQGSPVSDDLQTISTGAESSIRQ 416
[Close]
BLAST of Innexin vs. TrEMBL
Match: I7FTZ1 (Innexin OS=Dugesia japonica OX=6161 GN=Inx12 PE=2 SV=1)

HSP 1 Score: 792.727 bits (2046), Expect = 0.000e+0
Identity = 374/404 (92.57%), Postives = 393/404 (97.28%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDMAIVWLEAHTKIHKPSSNIV 1497
            MDSDSILKL R+FRSPLGGDGVSFIDVLNYQYSSAVLV+FIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEK +P+SDVELH+ EFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRK NS ++KL+CGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVT+CPVEIRKMGQ+KPAIYTLQCVLPINYFVEKIYAFLWFWFV+LACATSFNT  WF DLFV+NRQV FVS+YL+ALKQLSSTEERDCGRFV++VLG DGIFLL+AVANVASDLMALDVTGIMWRN++HAKVTGTEEDMAIVWLEAHTKIHKP SNIV
Sbjct:    1 MDSDSILKLTRVFRSPLGGDGVSFIDVLNYQYSSAVLVLFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKHIPESDVELHAVEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKKNSMLHKLMCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTYCPVEIRKMGQMKPAIYTLQCVLPINYFVEKIYAFLWFWFVTLACATSFNTFLWFFDLFVRNRQVAFVSSYLRALKQLSSTEERDCGRFVDIVLGKDGIFLLKAVANVASDLMALDVTGIMWRNFRHAKVTGTEEDMAIVWLEAHTKIHKPGSNIV 404
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A3Q0KNG6 (Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3 SV=1)

HSP 1 Score: 530.02 bits (1364), Expect = 0.000e+0
Identity = 228/385 (59.22%), Postives = 302/385 (78.44%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDM 1440
            M+ D++L++G++F +P GGDGV F+D LNYQ++  +L++FIA+IG RQY+GKPIQCWVPQEFT +WE+YAEN+CWVQNTYFL P   VP+ D EL    +I YYQWI IV+  QA+LC++PQI+WRVGS+R PVLLR++KEA +PDRELR+KA++CLVA LEEQA    R R+  STI ++LC   P   ++ LF +VR  FIGN++GQ+YLM+ F+GTN T FG+ +  D++ G +W+ SG FPRVTFC V +RKMGQIKPA YTLQCVLPINYFVEK+Y FLWFWFV L+  T  +TLQW  +  V  R++ ++  Y++A++QLS+TEERDC RFV   LG DG+ +L+ V+ V+SDL+ALDVT  +W NY+HAK+TGTEED+
Sbjct:    1 MNPDTVLRIGKVFETPYGGDGVDFVDQLNYQFTGGLLIIFIAVIGVRQYVGKPIQCWVPQEFTHSWEEYAENLCWVQNTYFLHPSDQVPEDDYELTKVRYIGYYQWIAIVLAGQAMLCWVPQILWRVGSKRLPVLLRSAKEASVPDRELRQKAISCLVATLEEQAESTARHRRATSTIKRILCSFRPNTRITFLFFIVRICFIGNSVGQIYLMKKFIGTNSTMFGMDVLNDLITGQEWETSGKFPRVTFCTVRVRKMGQIKPASYTLQCVLPINYFVEKVYVFLWFWFVILSIVTILSTLQWAFNTLVPVRRIAYIKQYIRAIRQLSNTEERDCTRFVNYNLGPDGVLILQVVSRVSSDLIALDVTATLWSNYRHAKITGTEEDI 385
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4S2LVS8 (Innexin OS=Opisthorchis felineus OX=147828 GN=inx PE=3 SV=1)

HSP 1 Score: 520.005 bits (1338), Expect = 5.368e-179
Identity = 224/385 (58.18%), Postives = 300/385 (77.92%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDM 1440
            M+ DS+L++G++F +P GG+GV F+D LNYQ++  +L++FIA+IG RQY+GKPIQCWVPQEFT +WE+YAEN+CWVQNTYFL P   VP+ D EL   + I YYQWI IV+  Q +L ++P ++WRVGS+R P+LLR++KEA +PDRELR+KA++CLVA LEEQA    R+R+  S + + LC L P   ++ LF +VRF FIGN++GQ+YLM+ F+GTN T FGV +  DI++G DW+ SG FPRVTFC V +RKMGQIKPA YTLQCVLPINYFVEK+Y FLWFWFV L C T  +T+ W  +  +  R++ ++  Y++A++QLS+TEERDC RFV   LG DG+ +L+ V+ V+SDL+ALDVT  +W NY+HAK+TGTEED+
Sbjct:    1 MNPDSVLRIGKVFYTPYGGEGVDFVDQLNYQFTGGLLIIFIAVIGIRQYVGKPIQCWVPQEFTHSWEEYAENLCWVQNTYFLHPSDNVPEDDYELTKVKHIGYYQWIAIVLAGQVMLSWVPYLLWRVGSKRLPILLRSAKEASVPDRELRQKAISCLVATLEEQAESTARYRRMTSGLKRFLCQLRPNTRITFLFFIVRFCFIGNSVGQIYLMKHFIGTNSTMFGVEVLNDIVSGKDWETSGKFPRVTFCTVRVRKMGQIKPASYTLQCVLPINYFVEKVYVFLWFWFVILTCITLLSTIHWAFNTLLPVRRIAYIKQYIRAIRQLSNTEERDCTRFVNNNLGPDGVLILQVVSRVSSDLIALDVTATLWSNYRHAKITGTEEDI 385
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A074ZMI3 (Innexin OS=Opisthorchis viverrini OX=6198 GN=inx PE=3 SV=1)

HSP 1 Score: 520.005 bits (1338), Expect = 5.368e-179
Identity = 224/385 (58.18%), Postives = 300/385 (77.92%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDM 1440
            M+ DS+L++G++F +P GG+GV F+D LNYQ++  +L++FIA+IG RQY+GKPIQCWVPQEFT +WE+YAEN+CWVQNTYFL P   VP+ D EL   + I YYQWI IV+  Q +L ++P ++WRVGS+R P+LLR++KEA +PDRELR+KA++CLVA LEEQA    R+R+  S + + LC L P   ++ LF +VRF FIGN++GQ+YLM+ F+GTN T FGV +  DI++G DW+ SG FPRVTFC V +RKMGQIKPA YTLQCVLPINYFVEK+Y FLWFWFV L C T  +T+ W  +  +  R++ ++  Y++A++QLS+TEERDC RFV   LG DG+ +L+ V+ V+SDL+ALDVT  +W NY+HAK+TGTEED+
Sbjct:    1 MNPDSVLRIGKVFYTPYGGEGVDFVDQLNYQFTGGLLIIFIAVIGIRQYVGKPIQCWVPQEFTHSWEEYAENLCWVQNTYFLHPSDNVPEDDYELTKVKHIGYYQWIAIVLAGQVMLSWVPYLLWRVGSKRLPILLRSAKEASVPDRELRQKAISCLVATLEEQAESTARYRRMTSGLKRFLCQLRPNTRITFLFFIVRFCFIGNSVGQIYLMKHFIGTNSTMFGVEVLNDIVSGKDWETSGKFPRVTFCTVRVRKMGQIKPASYTLQCVLPINYFVEKVYVFLWFWFVILTCITLLSTIHWAFNTLLPVRRIAYIKQYIRAIRQLSNTEERDCTRFVNNNLGPDGVLILQVVSRVSSDLIALDVTATLWSNYRHAKITGTEEDI 385
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A504YQY5 (Innexin OS=Fasciola gigantica OX=46835 GN=inx PE=3 SV=1)

HSP 1 Score: 518.85 bits (1335), Expect = 1.428e-178
Identity = 223/385 (57.92%), Postives = 300/385 (77.92%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDM 1440
            M+ D++L++G++F +P GG+GV F+D LNYQ++  +L++FIA+IG RQY+GKPIQCWVPQEFT +WE+YAEN+CWVQNTYFL P   VP+ D EL   + I YYQWI IV+  Q +L ++P ++WRVGS+R PVLLR++KEA +PDRELR+KA++CLVA LEEQA    R+R+  S + + LC L P   ++ LF +VRF F+GN+IGQ+YLM++F+GTN T FG+ +  D++ G DW+ SG FPRVTFC V +RKMGQIKPA YTLQCVLPINYFVEK+Y FLWFWFV L C T  +T+ W  +  +  R+V ++  Y++A++QLS+TEERDC RFV   LG DG+ +L+ V+ V+SDL+ALDVT  +W NY+HAK+TGTEED+
Sbjct:    1 MNPDAVLRIGKVFYTPYGGEGVDFVDQLNYQFTGGLLIIFIAVIGIRQYVGKPIQCWVPQEFTHSWEEYAENLCWVQNTYFLHPSDQVPEDDYELTHVKHIGYYQWIAIVLAGQVMLSWIPYLLWRVGSKRLPVLLRSAKEASVPDRELRQKAISCLVATLEEQAESTARYRRMTSNLKRFLCQLRPNTRITFLFFIVRFCFLGNSIGQIYLMKNFIGTNSTMFGIDVLNDLITGKDWETSGKFPRVTFCTVRVRKMGQIKPASYTLQCVLPINYFVEKVYVFLWFWFVILTCVTILSTIHWAFNTLLPVRRVAYIKQYIRAIRQLSNTEERDCTRFVNNNLGPDGVLILQVVSRVSSDLIALDVTATLWSNYRHAKITGTEEDI 385
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000032206.1 (SMESG000032206.1)

HSP 1 Score: 794.267 bits (2050), Expect = 0.000e+0
Identity = 387/404 (95.79%), Postives = 387/404 (95.79%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDMAIVWLEAHTKIHKPSSNIV 1497
            MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAEL                 QLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDMAIVWLEAHTKIHKPSSNIV
Sbjct:    1 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELR----------------QLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDMAIVWLEAHTKIHKPSSNIV 388
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000068735.1 (SMESG000068735.1)

HSP 1 Score: 495.738 bits (1275), Expect = 8.507e-173
Identity = 216/387 (55.81%), Postives = 302/387 (78.04%), Query Frame = 1 
Query:  283 LMDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDMA 1443
            LM+S  + K+GR+F++P GG+GV F D LNYQ++S ++V+FI I+  RQY+GKPIQCWVPQEFT+AWE+YAEN+CWV NTYFL  ++ +P  D E  + ++ISYYQWIVIV+  QA+L ++P + WRV SRR PVLLR+++EA+LPDR+LR KAV+C+VA+LEEQA    R R+      + L GL P   L+VLF+VVR +FIGNA+GQ+YLM+ F+G+N+  FG  + +D+LAG DW+++G+FPRVT+C + +R+MGQ+K A YTLQCVLPIN+F+EK+Y FLWFWF+ +A  T  +TLQW  +  +  ++V +V  YLKA++ ++STEERDC RFV   LG DG+FLL  V++ ASDL++LDVT  +W+N++ AK+TGTEED++
Sbjct:   11 LMESGFVFKIGRLFKTPYGGEGVDFADQLNYQFTSGLIVIFITIVSIRQYVGKPIQCWVPQEFTKAWEEYAENLCWVSNTYFLLADQEIPVDDKEFKNVKYISYYQWIVIVLAGQALLSWVPHLAWRVASRRLPVLLRSAREAVLPDRDLRVKAVSCMVASLEEQADATMRARRVKGIFRRCLGGLPPNTRLTVLFIVVRIMFIGNAVGQIYLMQKFVGSNNIMFGWTLLKDLLAGQDWELTGNFPRVTYCTILVRRMGQVKQASYTLQCVLPINHFIEKVYVFLWFWFILIAGITILSTLQWMFNTLLPMKRVHYVRQYLKAMRLITSTEERDCSRFVNNNLGPDGVFLLHVVSSTASDLISLDVTATLWKNFRQAKITGTEEDLS 397
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000033444.1 (SMESG000033444.1)

HSP 1 Score: 488.419 bits (1256), Expect = 4.196e-170
Identity = 225/385 (58.44%), Postives = 303/385 (78.70%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDM 1440
            M+S    ++G++FR P GG+GV F+D LNYQ++S +L+VFI IIG RQY+GKPIQCWVPQEFTR+WE+YAEN+CWVQNTYFL P + VP++D EL    +ISYYQW+ IV+  QAV+ ++P +IWRV SRR P+LLR+++EA  PDRE+RRKA++CLVAALEEQ     RFRK      K L G+ P A +++LF+ VR LFI N +GQ+++M+ F+GTN TTFG+ +F+D+L G++ ++S  FPRVT+C +++RKMGQIKP  YTLQCVLPINYFVEK+Y FLWFWF+ L+  T+ NT+QW +++ +  R+V FV  YLKALK ++ST+ERDC RFV   LG DGIFLL++V+ ++SDL+ALDVTG +W NYK AK+ G E+D+
Sbjct:    1 MESGIFFRIGQLFRVPYGGEGVDFVDQLNYQFTSGLLIVFIIIIGIRQYVGKPIQCWVPQEFTRSWEEYAENVCWVQNTYFLLPHEDVPNNDFELSKVRYISYYQWVAIVLAGQAVMSWVPHLIWRVWSRRVPILLRSAREASFPDREIRRKAISCLVAALEEQTESGARFRKIKGIFGKCLGGVNPTARVTLLFIFVRILFIANNVGQIFMMKKFIGTNETTFGITVFRDLLNGNEGQISETFPRVTYCTIKVRKMGQIKPGSYTLQCVLPINYFVEKVYVFLWFWFIILSILTTLNTVQWTLNVCLPLRRVQFVRQYLKALKVITSTDERDCVRFVRKNLGCDGIFLLQSVSRISSDLIALDVTGTLWNNYKRAKLAGNEDDI 385
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000051126.1 (SMESG000051126.1)

HSP 1 Score: 456.447 bits (1173), Expect = 1.630e-157
Identity = 203/389 (52.19%), Postives = 287/389 (73.78%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTI---YKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDMA 1443
            M++++ LK+G+ F +  GG+ + F+D LNYQYS+ +L +FI+IIG RQY+GKPIQCWVPQ+FT++WE+YAEN+CW+Q+TY L   + +P+ D E+HS ++ISYYQW+ IVMG QA++ YLP +IWR+ S+R P+LL+ ++EA +PDRE+R KA+ C+V  LEE      R+R+    I   Y   C   P   L++LF+ VR LFI N IGQ+YLM++F+ TN+T FG+ +  D+L G++WK  G+FPR+T+C + +RK GQIK A +T QCVLPIN+FVEKIY FLW WF  LA  T+ NTLQW + + +  +Q  F+  YLKALK +S++E R+C RFV   LG DGIF+L+AV+ V+SDL+ALDVT  +W NY+ AK+ G E+D+ 
Sbjct:    1 METNTFLKIGKHFHTAYGGNDIDFVDQLNYQYSTGLLFIFISIIGFRQYVGKPIQCWVPQQFTKSWEEYAENLCWIQSTYKLLDNEDIPEDDFEIHSLKYISYYQWVAIVMGGQAIMSYLPHLIWRLWSKRLPILLKTAREASIPDREMRAKAIQCIVTKLEEGTEAQIRYRRGEPGIFTRYVFFC-FNPSTRLTILFLFVRTLFILNNIGQIYLMKNFIKTNNTWFGIKVISDLLKGYEWKDYGNFPRITYCTINVRKFGQIKQASHTFQCVLPINHFVEKIYVFLWLWFTLLAVLTTLNTLQWGLIVCLPWKQTQFIQRYLKALKLISNSEGRECQRFVARNLGCDGIFVLQAVSKVSSDLIALDVTATLWTNYRQAKLNGAEDDIT 388
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000016539.1 (SMESG000016539.1)

HSP 1 Score: 452.595 bits (1163), Expect = 5.206e-156
Identity = 214/400 (53.50%), Postives = 300/400 (75.00%), Query Frame = 1 
Query:  286 MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYIGKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEFISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELRRKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRFLFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFCPVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTLQWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLLRAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDMAIVWLEAHTKIHKPS 1485
            MDS SIL+ G +F    GG GV F+D LN+Q++ A++++ I++I  RQYIGKPIQCWVPQEFT AWEDY E++CWVQNTYFL P + VP +D+E    + ++YYQW+ I +G QAVL YLP + W++GS RFP+LLR+++EA LPD++LR+KA++ L A++EEQA  + RF++NNS IY+ +C   P +  + +F+V R L IGN++GQ+YLM+ +LG  H  FG+ I + + +G+DWK SG+FPRVT+C V IR+ G +K A YT+QCVL +NYF+EK+Y FLWFWF SLAC T  NTL W I+L +  R+  F++ YL+ALKQ+SS +ERDC RFV+ +LG DG+ LLRAV++ ASDL+ALDV+  +W  YK ++ T T++D++  +LE    IHK S
Sbjct:    1 MDSGSILRFGNLFHLNYGG-GVDFVDKLNHQFTGAIILIIISLISARQYIGKPIQCWVPQEFTHAWEDYLEHMCWVQNTYFLLPSQPVPINDLETFDQKHVTYYQWVTIFLGLQAVLSYLPHLFWQLGSHRFPLLLRSAREAALPDKDLRKKAISILTASIEEQAEFSARFQRNNSPIYRFICSFAPNSRNTTIFLVSRVLSIGNSVGQIYLMQTYLGYRHPFFGIQILRSVTSGNDWKQSGYFPRVTYCRVLIRRWG-VKDASYTVQCVLSLNYFLEKVYVFLWFWFFSLACVTFCNTLMWAINLCIPFRRNQFITQYLRALKQVSSNDERDCDRFVKNILGADGVLLLRAVSSAASDLIALDVSAKLWAKYKRSRFTCTDDDLS-RFLE---NIHKSS 394
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inx-131.345e-8238.12Innexin [Source:UniProtKB/TrEMBL;Acc:O44887][more]
unc-98.376e-8137.88Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O0... [more]
inx-15.874e-7733.96Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-15.874e-7733.96Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-16.537e-7634.45Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shakB9.025e-2027.17gene:FBgn0085387 transcript:FBtr0112571[more]
Inx21.645e-1925.26gene:FBgn0027108 transcript:FBtr0301860[more]
Inx21.645e-1925.26gene:FBgn0027108 transcript:FBtr0071005[more]
Inx21.645e-1925.26gene:FBgn0027108 transcript:FBtr0332314[more]
Inx21.645e-1925.26gene:FBgn0027108 transcript:FBtr0071006[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O01393|UNC9_CAEEL1.065e-7937.88Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q03412|UNC7_CAEEL1.749e-6831.44Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q27295|EAT5_CAEEL9.164e-6131.81Innexin eat-5 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|Q19746|INX3_CAEEL2.881e-6032.25Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
sp|Q23157|INX11_CAEEL4.078e-5831.94Innexin-11 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
I7FTZ10.000e+092.57Innexin OS=Dugesia japonica OX=6161 GN=Inx12 PE=2 ... [more]
A0A3Q0KNG60.000e+059.22Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3... [more]
A0A4S2LVS85.368e-17958.18Innexin OS=Opisthorchis felineus OX=147828 GN=inx ... [more]
A0A074ZMI35.368e-17958.18Innexin OS=Opisthorchis viverrini OX=6198 GN=inx P... [more]
A0A504YQY51.428e-17857.92Innexin OS=Fasciola gigantica OX=46835 GN=inx PE=3... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000032206.10.000e+095.79SMESG000032206.1[more]
SMESG000068735.18.507e-17355.81SMESG000068735.1[more]
SMESG000033444.14.196e-17058.44SMESG000033444.1[more]
SMESG000051126.11.630e-15752.19SMESG000051126.1[more]
SMESG000016539.15.206e-15653.50SMESG000016539.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015595 ID=SMED30015595|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1709bp
TAAGATGTGCCATGAATGAACTAATTAATCGACCAATCAAAATCAAACAC
GCACGATTTTAACTGCCAGTGGAATTGAACGAAATCAGCAGGAGTAAAAT
AAATTCAACGTTCATTTTAAACAAAAGTGAAGAGAAACTTTTCTACTGCC
AGTACAGTAATAAAAAAAAACTAATCCCGCACATTTGTACCAGTTCAAAA
TCAAAAATTCAATCGCTAGTGTTGGAATTGAACAAAATGAAAACAGTCTC
GCTGTGGAAGTTTTAATTGTTGATTGACAATCCTCATGGATTCTGATTCG
ATTCTCAAATTAGGGCGAATATTTCGCTCACCTCTTGGAGGCGATGGAGT
TAGCTTTATAGACGTGTTGAATTATCAGTACAGTTCCGCGGTTCTCGTCG
TGTTCATCGCAATTATCGGCACTCGGCAATATATAGGGAAACCAATTCAG
TGTTGGGTGCCACAGGAGTTCACTCGAGCATGGGAAGATTACGCGGAAAA
CATTTGTTGGGTGCAAAATACATACTTTCTGCCGCCGGAAAAAGCCGTTC
CCGATTCAGACGTTGAGCTTCATTCGGCAGAATTTATCAGTTACTATCAG
TGGATTGTTATCGTTATGGGAGCTCAAGCTGTTCTCTGTTATCTGCCACA
GATTATCTGGAGAGTCGGATCGAGACGATTTCCAGTGTTGTTGAGAAATT
CTAAAGAAGCAATTCTTCCAGACCGAGAGCTTCGACGGAAAGCAGTCGCC
TGTTTGGTGGCGGCTCTCGAAGAACAAGCGATAAGAAATTGTCGATTTCG
AAAAAACAATTCCACGATTTATAAATTGCTTTGTGGTCTTGGTCCAGGAG
CGGAACTAAGTGTTCTTTTCATGGTCGTTCGATTTCTTTTTATTGGAAAC
GCTATAGGACAATTGTATTTGATGAGAGATTTCTTGGGTACAAATCACAC
AACTTTTGGAGTGATGATTTTTCAAGACATTCTAGCCGGTCACGATTGGA
AGGTTTCTGGCCATTTTCCTCGAGTTACTTTTTGTCCGGTTGAAATTAGA
AAGATGGGACAAATCAAACCAGCGATATACACTTTGCAGTGTGTTCTGCC
AATAAATTATTTTGTTGAAAAGATTTATGCTTTCCTTTGGTTTTGGTTTG
TCAGTCTTGCCTGTGCCACTAGTTTCAATACTCTGCAATGGTTCATTGAC
CTTTTTGTTAAAAACAGACAAGTTGTTTTTGTATCAAACTATTTAAAAGC
TCTAAAACAATTGTCAAGCACTGAAGAAAGAGATTGCGGTCGATTTGTGG
AAGTTGTTCTTGGGAATGATGGAATATTTCTTCTGCGAGCAGTTGCCAAC
GTTGCGAGTGATCTTATGGCTCTTGATGTGACGGGTATAATGTGGAGGAA
CTATAAACATGCCAAGGTAACTGGAACAGAAGAAGACATGGCTATAGTGT
GGTTAGAAGCTCATACAAAGATACATAAACCTTCATCAAATATTGTTTGA
TAGTTGTTATCTTTTCCTATTAATATTGTACATAATCTCGATTTACTGAC
CTTTATTTATTGACTCCAGTAAATCTTTTCTTCCTTGTAAATGACCAAAT
CGTATGATTGAAGTCTTCGACCTATTAATAATTATAAAATAAGTTTTATT
ACTTTATTTTTGCAATTGGATTGAGTAAAAGTTGTTTTATTAGCTACCAT
AATTTGGAA
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protein sequence of SMED30015595-orf-1

>SMED30015595-orf-1 ID=SMED30015595-orf-1|Name=SMED30015595-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=405bp
MDSDSILKLGRIFRSPLGGDGVSFIDVLNYQYSSAVLVVFIAIIGTRQYI
GKPIQCWVPQEFTRAWEDYAENICWVQNTYFLPPEKAVPDSDVELHSAEF
ISYYQWIVIVMGAQAVLCYLPQIIWRVGSRRFPVLLRNSKEAILPDRELR
RKAVACLVAALEEQAIRNCRFRKNNSTIYKLLCGLGPGAELSVLFMVVRF
LFIGNAIGQLYLMRDFLGTNHTTFGVMIFQDILAGHDWKVSGHFPRVTFC
PVEIRKMGQIKPAIYTLQCVLPINYFVEKIYAFLWFWFVSLACATSFNTL
QWFIDLFVKNRQVVFVSNYLKALKQLSSTEERDCGRFVEVVLGNDGIFLL
RAVANVASDLMALDVTGIMWRNYKHAKVTGTEEDMAIVWLEAHTKIHKPS
SNIV*
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Aliases
The feature 'Innexin' has the following synonyms
Synonym
Dj-inx12
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002142parenchyma
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR000990Innexin
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000990InnexinPRINTSPR01262INNEXINcoord: 45..56
score: 48.0
coord: 103..125
score: 43.13
coord: 269..285
score: 60.94
coord: 195..209
score: 27.47
coord: 73..82
score: 54.0
coord: 243..252
score: 57.2
IPR000990InnexinPFAMPF00876Innexincoord: 24..373
e-value: 4.1E-102
score: 342.1
IPR000990InnexinPANTHERPTHR11893INNEXINcoord: 23..383
IPR000990InnexinPROSITEPS51013PANNEXINcoord: 17..379
score: 30.4
NoneNo IPR availablePANTHERPTHR11893:SF36INNEXIN-5coord: 23..383
NoneNo IPR availableTMHMMTMhelixcoord: 21..43
NoneNo IPR availableTMHMMTMhelixcoord: 106..128
NoneNo IPR availableTMHMMTMhelixcoord: 181..203
NoneNo IPR availableTMHMMTMhelixcoord: 282..304