Nesprin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015584 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 53Note: Hover over icons to view figure legend
Homology
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 204.527 bits (519), Expect = 7.480e-54 Identity = 122/266 (45.86%), Postives = 173/266 (65.04%), Query Frame = 1
Query: 142 IGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSASDKG-----------VKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
I N++++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G MK++H ++N+ AL +L RKIKLVNIN +DI +G+P IVLGL+W IIL+FQI+E +L S + +V ++ + S K LL W+Q ++ + + DFGKSW SG+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 14 IANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 279
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 202.216 bits (513), Expect = 3.316e-52 Identity = 122/266 (45.86%), Postives = 173/266 (65.04%), Query Frame = 1
Query: 142 IGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
I N++++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G MK++H ++N+ AL +L RKIKLVNIN +DI +G+P IVLGL+W IIL+FQI+E +L S + +V ++ + S K LL W+Q ++ + + DFGKSW SG+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 14 IANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 279
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 204.142 bits (518), Expect = 4.926e-51 Identity = 121/266 (45.49%), Postives = 172/266 (64.66%), Query Frame = 1
Query: 142 IGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE--------HELDKKSQQSGAVRQANANNSASDKGVKLK--------LLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
I N++++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G MK++H ++N+ AL +L RKIKLVNIN +DI +G+P IVLGL+W IIL+FQI+E L + ++ + + S + V K LL W+Q ++ + + DFGKSW SG+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 14 IANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 279
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 203.756 bits (517), Expect = 4.979e-51 Identity = 122/266 (45.86%), Postives = 173/266 (65.04%), Query Frame = 1
Query: 142 IGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
I N++++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G MK++H ++N+ AL +L RKIKLVNIN +DI +G+P IVLGL+W IIL+FQI+E +L S + +V ++ + S K LL W+Q ++ + + DFGKSW SG+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 14 IANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 279
BLAST of Nesprin-1 vs. Ensembl Human
Match: SYNE1 (spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]) HSP 1 Score: 190.274 bits (482), Expect = 2.865e-50 Identity = 119/269 (44.24%), Postives = 169/269 (62.83%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERK-------IKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE--------HELDKKSQQSGAVRQANANNSASDKGVKLK--------LLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
+++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G MK++H ++N+ AL +L RK IKLVNIN +DI +G+P IVLGL+W IIL+FQI+E L + ++ + + S + V K LL W+Q ++ + + DFGKSW SG+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 1 MQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 269
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 156.762 bits (395), Expect = 7.133e-37 Identity = 98/267 (36.70%), Postives = 143/267 (53.56%), Query Frame = 1
Query: 160 KYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXX----XXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKG-----VKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKN---LDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPR 924
KY DE+D +QKKTFTKW+NK+L K D + DLFVD+RDG LI LLE L+G ++KE G + H + NV+ L++L ++ IKLVNI P DIVEG + L +I + Q L+ + + + N+ S G + LL W + + + + +F SW G+AF+A++ + + +D + D N L++AF A+R G+ +LLD+EDV PDEKSI+TYVS PE R
Sbjct: 32 KYNDERDNVQKKTFTKWVNKHLSKTDHK--IDDLFVDLRDGYALIALLEALTGERIQKENG--YTRFHRIQNVQYCLDFLKKKNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKI-SSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSR 293
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 156.762 bits (395), Expect = 7.139e-37 Identity = 98/267 (36.70%), Postives = 143/267 (53.56%), Query Frame = 1
Query: 160 KYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXX----XXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKG-----VKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKN---LDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPR 924
KY DE+D +QKKTFTKW+NK+L K D + DLFVD+RDG LI LLE L+G ++KE G + H + NV+ L++L ++ IKLVNI P DIVEG + L +I + Q L+ + + + N+ S G + LL W + + + + +F SW G+AF+A++ + + +D + D N L++AF A+R G+ +LLD+EDV PDEKSI+TYVS PE R
Sbjct: 32 KYNDERDNVQKKTFTKWVNKHLSKTDHK--IDDLFVDLRDGYALIALLEALTGERIQKENG--YTRFHRIQNVQYCLDFLKKKNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKI-SSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSR 293
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 156.762 bits (395), Expect = 7.349e-37 Identity = 102/267 (38.20%), Postives = 146/267 (54.68%), Query Frame = 1
Query: 160 KYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXX----XXXXXXXEHELDKKSQQSGAVRQANANNSASDKG-----VKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKN---LDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPR 924
KY DE+D +QKKTFTKW+NK+L K D + DLFVD+RDG LI LLE L+G ++KE G + H + NV+ L++L ++ IKLVNI P DIVEG + LGLIW I + Q L+ + + + N+ S G + LL W + + + + +F SW G+AF+A++ + + +D + D N L++AF A+R G+ +LLD+EDV PDEKSI+TYVS PE R
Sbjct: 32 KYNDERDNVQKKTFTKWVNKHLSKTDHK--IDDLFVDLRDGYALIALLEALTGERIQKENG--YTRFHRIQNVQYCLDFLKKKNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKI-SSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSR 293
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 156.762 bits (395), Expect = 7.504e-37 Identity = 98/267 (36.70%), Postives = 143/267 (53.56%), Query Frame = 1
Query: 160 KYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXX----XXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKG-----VKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKN---LDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPR 924
KY DE+D +QKKTFTKW+NK+L K D + DLFVD+RDG LI LLE L+G ++KE G + H + NV+ L++L ++ IKLVNI P DIVEG + L +I + Q L+ + + + N+ S G + LL W + + + + +F SW G+AF+A++ + + +D + D N L++AF A+R G+ +LLD+EDV PDEKSI+TYVS PE R
Sbjct: 32 KYNDERDNVQKKTFTKWVNKHLSKTDHK--IDDLFVDLRDGYALIALLEALTGERIQKENG--YTRFHRIQNVQYCLDFLKKKNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKI-SSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSR 293
BLAST of Nesprin-1 vs. Ensembl Celegans
Match: vab-10 (VAB-10B protein [Source:UniProtKB/TrEMBL;Acc:G5EFM4]) HSP 1 Score: 156.377 bits (394), Expect = 8.685e-37 Identity = 98/267 (36.70%), Postives = 143/267 (53.56%), Query Frame = 1
Query: 160 KYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXX----XXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKG-----VKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKN---LDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPR 924
KY DE+D +QKKTFTKW+NK+L K D + DLFVD+RDG LI LLE L+G ++KE G + H + NV+ L++L ++ IKLVNI P DIVEG + L +I + Q L+ + + + N+ S G + LL W + + + + +F SW G+AF+A++ + + +D + D N L++AF A+R G+ +LLD+EDV PDEKSI+TYVS PE R
Sbjct: 32 KYNDERDNVQKKTFTKWVNKHLSKTDHK--IDDLFVDLRDGYALIALLEALTGERIQKENG--YTRFHRIQNVQYCLDFLKKKNIKLVNIRPEDIVEGNGKLTLGLIWTIILNFQVSVIRQRLLLESSQHEQMSAKHTTTNSQVSLHGSDATSARDALLQWARRVTAGYPRVNVNNFSSSWRDGLAFNAILHRYRSSAIDWNKI-SSDSVSNTERLNNAFAAADREFGVERLLDAEDVDTNNPDEKSIITYVSSLYNALPHEPEMSR 293
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0332405) HSP 1 Score: 239.965 bits (611), Expect = 7.954e-62 Identity = 223/806 (27.67%), Postives = 400/806 (49.63%), Query Frame = 1
Query: 139 QIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASD------------KGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVN---DKIKRFIINVKESRIEKLKQIENFNDVF--------------KLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLL-HK---IASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIER--------------EIKYIETSLRTYIEEWHKMEELYNETVDWM-------NSTDDFSIS-PQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHEN--KSLHVDNL---RKEYKIKVENIKKWLEKSEA-LESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKL 2373
Q + I++ ++EQ+ +QKKTFT WIN YL K L + DL D+RDG LI LLEVLSG + E+G +++ H+LSN AL +L+ ++IKLVNINP+D+V+G+P +VLGLIW IIL+FQI+E+ + + G ++ +S + +G + LL W+ N +P++ + + DFG SW G+AF ALI+ NLV++ + + ++ L++AFD+AE LGIAKLLD+EDV KPDEKSIMTYV+QFL K P+ A ++ V D+++RF++ K + E + + +F F + LK +E + Q S +++ ++ + ++ WLLD + + + KWL +E++L +N D+ ++ E ++ +++E++ F + P KR + ++ + ++ERR+Q+V + R +L L HK IA L + E K++ W ++ +L +++ ++ + D+++++ +K + I+DI+R E+K + SL + W +L +W+ N ++D + Q+ K K + + +L + + L ++ ++ F R N + +H ++ R+EYK +E + +WL +E+ L+ + +++ V EY Q L + ++ +E FK +S+ Q + + S++E ++M+ LK +K L+ + R +L KL
Sbjct: 616 QYDSHIKEKREEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLASKRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLH-------------KYPEPKGASRDQSHVQQEADELRRFLVE-KTTEYEPMVMMSSFPRDFGEYLLARSEVDAHLAAYNRLKQLIESQSGFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGTVGKWLAEAEKLL---MDN--DIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPV----AQQIPLEQLRNMERRLQEVGPKAAERRIRLKFLEHKCCLIAFLNLVEN----KMRGWTGKYGHEEKVAQQLEQYKNFVSRNKIFQEFQKAFVDMQQVVE---EYKRDGNVPRKEINDIDRFMYETEERWKRVSMELKCCQNSLEEVVNCWRSWNQLAPTCEEWLQLAEQKVNQSEDERLDFFQDIPVWKDKFDALASSANYLIASCEEPIAQQLRQRHGALSERFERLFANTKQYMHAGDIIRSRQEYKSGIEQLSRWLRGAESVLDQRQVLGNSEQVKEYGQQLQQLASEIDDNEELFKTISRNFQSLIQDLSRDEVDKMMKLLKQEKESLVRI---RAQLPAKL 1388
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0303385) HSP 1 Score: 239.965 bits (611), Expect = 8.227e-62 Identity = 223/806 (27.67%), Postives = 400/806 (49.63%), Query Frame = 1
Query: 139 QIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASD------------KGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVN---DKIKRFIINVKESRIEKLKQIENFNDVF--------------KLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLL-HK---IASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIER--------------EIKYIETSLRTYIEEWHKMEELYNETVDWM-------NSTDDFSIS-PQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHEN--KSLHVDNL---RKEYKIKVENIKKWLEKSEA-LESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKL 2373
Q + I++ ++EQ+ +QKKTFT WIN YL K L + DL D+RDG LI LLEVLSG + E+G +++ H+LSN AL +L+ ++IKLVNINP+D+V+G+P +VLGLIW IIL+FQI+E+ + + G ++ +S + +G + LL W+ N +P++ + + DFG SW G+AF ALI+ NLV++ + + ++ L++AFD+AE LGIAKLLD+EDV KPDEKSIMTYV+QFL K P+ A ++ V D+++RF++ K + E + + +F F + LK +E + Q S +++ ++ + ++ WLLD + + + KWL +E++L +N D+ ++ E ++ +++E++ F + P KR + ++ + ++ERR+Q+V + R +L L HK IA L + E K++ W ++ +L +++ ++ + D+++++ +K + I+DI+R E+K + SL + W +L +W+ N ++D + Q+ K K + + +L + + L ++ ++ F R N + +H ++ R+EYK +E + +WL +E+ L+ + +++ V EY Q L + ++ +E FK +S+ Q + + S++E ++M+ LK +K L+ + R +L KL
Sbjct: 616 QYDSHIKEKREEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLASKRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLH-------------KYPEPKGASRDQSHVQQEADELRRFLVE-KTTEYEPMVMMSSFPRDFGEYLLARSEVDAHLAAYNRLKQLIESQSGFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGTVGKWLAEAEKLL---MDN--DIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPV----AQQIPLEQLRNMERRLQEVGPKAAERRIRLKFLEHKCCLIAFLNLVEN----KMRGWTGKYGHEEKVAQQLEQYKNFVSRNKIFQEFQKAFVDMQQVVE---EYKRDGNVPRKEINDIDRFMYETEERWKRVSMELKCCQNSLEEVVNCWRSWNQLAPTCEEWLQLAEQKVNQSEDERLDFFQDIPVWKDKFDALASSANYLIASCEEPIAQQLRQRHGALSERFERLFANTKQYMHAGDIIRSRQEYKSGIEQLSRWLRGAESVLDQRQVLGNSEQVKEYGQQLQQLASEIDDNEELFKTISRNFQSLIQDLSRDEVDKMMKLLKQEKESLVRI---RAQLPAKL 1388
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0303383) HSP 1 Score: 239.58 bits (610), Expect = 1.113e-61 Identity = 222/806 (27.54%), Postives = 399/806 (49.50%), Query Frame = 1
Query: 139 QIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASD------------KGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVN---DKIKRFIINVKESRIEKLKQIENFNDVF--------------KLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLL-HK---IASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIER--------------EIKYIETSLRTYIEEWHKMEELYNETVDWM-------NSTDDFSIS-PQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHEN--KSLHVDNL---RKEYKIKVENIKKWLEKSEA-LESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKL 2373
Q + I++ ++EQ+ +QKKTFT WIN YL K L + DL D+RDG LI LLEVLSG + E+G +++ H+LSN AL +L+ ++IKLVNINP+D+V+G+P +VLGLIW IIL+FQI+E+ + + G ++ +S + +G + LL W+ N +P++ + + DFG SW G+AF ALI+ NLV++ + + ++ L++AFD+AE LGIAKLLD+EDV KPDEKSIMTYV+QFL K P+ A ++ V D+++RF++ K + E + + +F F + LK +E + Q S +++ ++ + ++ WLLD + + + KWL +E++L + D+ ++ E ++ +++E++ F + P KR + ++ + ++ERR+Q+V + R +L L HK IA L + E K++ W ++ +L +++ ++ + D+++++ +K + I+DI+R E+K + SL + W +L +W+ N ++D + Q+ K K + + +L + + L ++ ++ F R N + +H ++ R+EYK +E + +WL +E+ L+ + +++ V EY Q L + ++ +E FK +S+ Q + + S++E ++M+ LK +K L+ + R +L KL
Sbjct: 616 QYDSHIKEKREEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLASKRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLH-------------KYPEPKGASRDQSHVQQEADELRRFLVE-KTTEYEPMVMMSSFPRDFGEYLLARSEVDAHLAAYNRLKQLIESQSGFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGTVGKWLAEAEKLLMDN-----DIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPV----AQQIPLEQLRNMERRLQEVGPKAAERRIRLKFLEHKCCLIAFLNLVEN----KMRGWTGKYGHEEKVAQQLEQYKNFVSRNKIFQEFQKAFVDMQQVVE---EYKRDGNVPRKEINDIDRFMYETEERWKRVSMELKCCQNSLEEVVNCWRSWNQLAPTCEEWLQLAEQKVNQSEDERLDFFQDIPVWKDKFDALASSANYLIASCEEPIAQQLRQRHGALSERFERLFANTKQYMHAGDIIRSRQEYKSGIEQLSRWLRGAESVLDQRQVLGNSEQVKEYGQQLQQLASEIDDNEELFKTISRNFQSLIQDLSRDEVDKMMKLLKQEKESLVRI---RAQLPAKL 1388
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0332404) HSP 1 Score: 238.424 bits (607), Expect = 2.410e-61 Identity = 222/801 (27.72%), Postives = 397/801 (49.56%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDK------------GVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVN---DKIKRFIINVKESRIEKLKQIENFNDVF--------------KLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLL-HK---IASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIER--------------EIKYIETSLRTYIEEWHKMEELYNETVDWM-------NSTDDFSIS-PQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHEN--KSLHVDNL---RKEYKIKVENIKKWLEKSEA-LESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKL 2373
I + ++EQ+ +QKKTFT WIN YL K L + DL D+RDG LI LLEVLSG + E+G +++ H+LSN AL +L+ ++IKLVNINP+D+V+G+P +VLGLIW IIL+FQI+E+ + + G ++ +S ++ G + LL W+ N +P++ + + DFG SW G+AF ALI+ NLV++ + + ++ L++AFD+AE LGIAKLLD+EDV KPDEKSIMTYV+QFL K P+ A ++ V D+++RF++ K + E + + +F F + LK +E + Q S +++ ++ + ++ WLLD + + + KWL +E++L +N D+ ++ E ++ +++E++ F + P KR + ++ + ++ERR+Q+V + R +L L HK IA L + E K++ W ++ +L +++ ++ + D+++++ +K + I+DI+R E+K + SL + W +L +W+ N ++D + Q+ K K + + +L + + L ++ ++ F R N + +H ++ R+EYK +E + +WL +E+ L+ + +++ V EY Q L + ++ +E FK +S+ Q + + S++E ++M+ LK +K L+ + R +L KL
Sbjct: 262 ILQLQEEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLASKRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLH-------------KYPEPKGASRDQSHVQQEADELRRFLVE-KTTEYEPMVMMSSFPRDFGEYLLARSEVDAHLAAYNRLKQLIESQSGFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGTVGKWLAEAEKLL---MDN--DIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPV----AQQIPLEQLRNMERRLQEVGPKAAERRIRLKFLEHKCCLIAFLNLVEN----KMRGWTGKYGHEEKVAQQLEQYKNFVSRNKIFQEFQKAFVDMQQVVE---EYKRDGNVPRKEINDIDRFMYETEERWKRVSMELKCCQNSLEEVVNCWRSWNQLAPTCEEWLQLAEQKVNQSEDERLDFFQDIPVWKDKFDALASSANYLIASCEEPIAQQLRQRHGALSERFERLFANTKQYMHAGDIIRSRQEYKSGIEQLSRWLRGAESVLDQRQVLGNSEQVKEYGQQLQQLASEIDDNEELFKTISRNFQSLIQDLSRDEVDKMMKLLKQEKESLVRI---RAQLPAKL 1029
BLAST of Nesprin-1 vs. Ensembl Fly
Match: Msp300 (gene:FBgn0261836 transcript:FBtr0303388) HSP 1 Score: 238.424 bits (607), Expect = 2.493e-61 Identity = 222/801 (27.72%), Postives = 397/801 (49.56%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDK------------GVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVN---DKIKRFIINVKESRIEKLKQIENFNDVF--------------KLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLL-HK---IASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIER--------------EIKYIETSLRTYIEEWHKMEELYNETVDWM-------NSTDDFSIS-PQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHEN--KSLHVDNL---RKEYKIKVENIKKWLEKSEA-LESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKL 2373
I + ++EQ+ +QKKTFT WIN YL K L + DL D+RDG LI LLEVLSG + E+G +++ H+LSN AL +L+ ++IKLVNINP+D+V+G+P +VLGLIW IIL+FQI+E+ + + G ++ +S ++ G + LL W+ N +P++ + + DFG SW G+AF ALI+ NLV++ + + ++ L++AFD+AE LGIAKLLD+EDV KPDEKSIMTYV+QFL K P+ A ++ V D+++RF++ K + E + + +F F + LK +E + Q S +++ ++ + ++ WLLD + + + KWL +E++L +N D+ ++ E ++ +++E++ F + P KR + ++ + ++ERR+Q+V + R +L L HK IA L + E K++ W ++ +L +++ ++ + D+++++ +K + I+DI+R E+K + SL + W +L +W+ N ++D + Q+ K K + + +L + + L ++ ++ F R N + +H ++ R+EYK +E + +WL +E+ L+ + +++ V EY Q L + ++ +E FK +S+ Q + + S++E ++M+ LK +K L+ + R +L KL
Sbjct: 262 ILQLQEEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLASKRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLH-------------KYPEPKGASRDQSHVQQEADELRRFLVE-KTTEYEPMVMMSSFPRDFGEYLLARSEVDAHLAAYNRLKQLIESQSGFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGTVGKWLAEAEKLL---MDN--DIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPV----AQQIPLEQLRNMERRLQEVGPKAAERRIRLKFLEHKCCLIAFLNLVEN----KMRGWTGKYGHEEKVAQQLEQYKNFVSRNKIFQEFQKAFVDMQQVVE---EYKRDGNVPRKEINDIDRFMYETEERWKRVSMELKCCQNSLEEVVNCWRSWNQLAPTCEEWLQLAEQKVNQSEDERLDFFQDIPVWKDKFDALASSANYLIASCEEPIAQQLRQRHGALSERFERLFANTKQYMHAGDIIRSRQEYKSGIEQLSRWLRGAESVLDQRQVLGNSEQVKEYGQQLQQLASEIDDNEELFKTISRNFQSLIQDLSRDEVDKMMKLLKQEKESLVRI---RAQLPAKL 1029
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: syne1a (spectrin repeat containing, nuclear envelope 1a [Source:ZFIN;Acc:ZDB-GENE-030131-4172]) HSP 1 Score: 186.037 bits (471), Expect = 1.659e-45 Identity = 121/266 (45.49%), Postives = 174/266 (65.41%), Query Frame = 1
Query: 166 KDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERK-------IKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDK----------------GVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLE 894
+DEQ+ +QK+TFTKWIN +L K + L+V DLF D++DG+ML+ LLEVLSG + E+G ++++H+++NV AL +L R+ IKLVNIN +D+V+G+P IVLGLIW IIL+FQI+E + Q + ++ +S S + G K LL W+QN + + + DFG SW +G+AFHA+I P+LV+M+ V + ++NL+ AF +AER LGI +LLD EDV +KPDEKSIMTYV+QFL+
Sbjct: 35 RDEQEAVQKRTFTKWINSHLAKRNPPLVVSDLFEDVKDGVMLLALLEVLSGHKLPCEQGRKLRRIHWVANVGRALKFLEGRRVRQSIPTIKLVNINTTDVVDGRPSIVLGLIWTIILYFQIEELTSHLPALQPQSSSNSSVESSNSTETSSPPVKRKPRLSFQGGAKRALLKWVQNTATKRMGLDVKDFGPSWRTGVAFHAVIFALRPHLVNMERVWRRGNRENLEEAFSLAERELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLK 300
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: pleca (plectin a [Source:ZFIN;Acc:ZDB-GENE-030131-8984]) HSP 1 Score: 175.252 bits (443), Expect = 3.107e-42 Identity = 112/256 (43.75%), Postives = 151/256 (58.98%), Query Frame = 1
Query: 148 NIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPE 915
N+ KYKDE+D +QKKTFTKW+NK+L K + + DL+ D+RDG LI LLEVLSG T+ +E+G + H L NV+IAL++L R++KLVNI DI +G P + LGLIW IIL FQ + N + D K KLL W Q ++ + +F SW G F+A+I PNL+D+ V + +NL+ AF IAER LG+ +LLD EDV PDEKSI+TYVS ++ P+
Sbjct: 24 NVREKYKDERDRVQKKTFTKWVNKHLVKAQRH--ITDLYEDLRDGHNLISLLEVLSGETLPREKG--RMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ---------------ISDIQVNGQSDDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHKHRPNLIDINKVYRQTNLENLEQAFSIAERDLGVTRLLDPEDVDVPHPDEKSIITYVSSMYDVMPRVPD 260
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: plecb (plectin b [Source:ZFIN;Acc:ZDB-GENE-100917-2]) HSP 1 Score: 172.555 bits (436), Expect = 1.751e-41 Identity = 115/271 (42.44%), Postives = 155/271 (57.20%), Query Frame = 1
Query: 166 KDEQDFIQKKTFTKWINKYLKKH---DSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNE 969
KDE+D +QKKTFTKW+NK+L KH ++ V DL+ D+RDG LI LLEVLSG T+ +ERG + H L NV+IAL++L R++KLVNI DI +G P + LGLIW IIL FQ + N + D K KLL W Q ++ + + +F SW G F+A+I P L+DM V + +NL+ AF +AE+ LG+ +LLD EDV PDEKSI+TYVS + P P + + AK+NE
Sbjct: 40 KDERDRVQKKTFTKWVNKHLIKHWRSETQRHVNDLYEDLRDGHNLISLLEVLSGETLPRERG--RMRFHKLQNVQIALDFLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ---------------ISDIQVNGQSDDMSAKEKLLFWSQRMVDGYHGIRCDNFTTSWRDGKLFNAIIHKHEPRLIDMPKVYRQTNMENLEQAFTVAEKELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAM---PRVP------DVQDGAKTNE 284
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: plecb (plectin b [Source:ZFIN;Acc:ZDB-GENE-100917-2]) HSP 1 Score: 171.4 bits (433), Expect = 4.947e-41 Identity = 109/246 (44.31%), Postives = 146/246 (59.35%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKH---DSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVS 882
I + DE+D +QKKTFTKW+NK+L KH ++ V DL+ D+RDG LI LLEVLSG T+ +ERG + H L NV+IAL++L R++KLVNI DI +G P + LGLIW IIL FQ + N + D K KLL W Q ++ + + +F SW G F+A+I P L+DM V + +NL+ AF +AE+ LG+ +LLD EDV PDEKSI+TYVS
Sbjct: 60 ILRIADERDRVQKKTFTKWVNKHLIKHWRSETQRHVNDLYEDLRDGHNLISLLEVLSGETLPRERG--RMRFHKLQNVQIALDFLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ---------------ISDIQVNGQSDDMSAKEKLLFWSQRMVDGYHGIRCDNFTTSWRDGKLFNAIIHKHEPRLIDMPKVYRQTNMENLEQAFTVAEKELGVTRLLDPEDVDVPHPDEKSIITYVS 288
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Match: plecb (plectin b [Source:ZFIN;Acc:ZDB-GENE-100917-2]) HSP 1 Score: 169.474 bits (428), Expect = 1.568e-40 Identity = 114/268 (42.54%), Postives = 153/268 (57.09%), Query Frame = 1
Query: 166 KDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNE 969
KDE+D +QKKTFTKW+NK+L K + V DL+ D+RDG LI LLEVLSG T+ +ERG + H L NV+IAL++L R++KLVNI DI +G P + LGLIW IIL FQ + N + D K KLL W Q ++ + + +F SW G F+A+I P L+DM V + +NL+ AF +AE+ LG+ +LLD EDV PDEKSI+TYVS + P P + + AK+NE
Sbjct: 40 KDERDRVQKKTFTKWVNKHLIKTQRH--VNDLYEDLRDGHNLISLLEVLSGETLPRERG--RMRFHKLQNVQIALDFLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ---------------ISDIQVNGQSDDMSAKEKLLFWSQRMVDGYHGIRCDNFTTSWRDGKLFNAIIHKHEPRLIDMPKVYRQTNMENLEQAFTVAEKELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAM---PRVP------DVQDGAKTNE 279
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 189.504 bits (480), Expect = 2.416e-46 Identity = 122/301 (40.53%), Postives = 176/301 (58.47%), Query Frame = 1
Query: 163 YKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERK--------IKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE--------HELDKKSQQSGAVRQANANNSASDKGV--------KLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKI--VLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDK 987
+ DEQ+ +QK+TFTKWIN +L K +++ +LF DI+DG LI LLEVLSG + E+G +K++H+++N+ AL +L R+ IKLVNIN +DI +G+P IVLGLIW IIL+FQI+E H + + +V + A + + + K LL W+Q + + + DFG SW +GIAFH++I P+LVDM I + + ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTY++QFL+ P+P ++ G DK
Sbjct: 29 FSDEQEAVQKRTFTKWINSHLAKRHPPMVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEGRRVMTFLIFQIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFLK---------------HYPDPHHTSLDGQEDK 314
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 171.4 bits (433), Expect = 6.904e-41 Identity = 106/250 (42.40%), Postives = 157/250 (62.80%), Query Frame = 1
Query: 196 TFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE--------HELDKKSQQSGAVRQANANNSASDKGV--------KLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKI--VLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
T +++ +L++H +++ +LF DI+DG LI LLEVLSG + E+G +K++H+++N+ AL +L R+IKLVNIN +DI +G+P IVLGLIW IIL+FQI+E H + + +V + A + + + K LL W+Q + + + DFG SW +GIAFH++I P+LVDM I + + ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTY++QFL
Sbjct: 29 TLNQYVISFLQRHPP-MVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEGRRIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFL 277
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 170.244 bits (430), Expect = 1.774e-40 Identity = 106/250 (42.40%), Postives = 157/250 (62.80%), Query Frame = 1
Query: 196 TFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE--------HELDKKSQQSGAVRQANANNSASDKGV--------KLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKI--VLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
T +++ +L++H +++ +LF DI+DG LI LLEVLSG + E+G +K++H+++N+ AL +L R+IKLVNIN +DI +G+P IVLGLIW IIL+FQI+E H + + +V + A + + + K LL W+Q + + + DFG SW +GIAFH++I P+LVDM I + + ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTY++QFL
Sbjct: 8 TLNQYVISFLQRHPP-MVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEGRRIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFL 256
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 169.859 bits (429), Expect = 2.193e-40 Identity = 106/250 (42.40%), Postives = 157/250 (62.80%), Query Frame = 1
Query: 196 TFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE--------HELDKKSQQSGAVRQANANNSASDKGV--------KLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKI--VLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
T +++ +L++H +++ +LF DI+DG LI LLEVLSG + E+G +K++H+++N+ AL +L R+IKLVNIN +DI +G+P IVLGLIW IIL+FQI+E H + + +V + A + + + K LL W+Q + + + DFG SW +GIAFH++I P+LVDM I + + ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTY++QFL
Sbjct: 8 TLNQYVISFLQRHPP-MVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEGRRIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFL 256
BLAST of Nesprin-1 vs. Ensembl Xenopus
Match: SYNE1 (spectrin repeat containing, nuclear envelope 1 [Source:NCBI gene;Acc:100145637]) HSP 1 Score: 169.474 bits (428), Expect = 2.339e-40 Identity = 106/250 (42.40%), Postives = 157/250 (62.80%), Query Frame = 1
Query: 196 TFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE--------HELDKKSQQSGAVRQANANNSASDKGV--------KLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKI--VLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
T +++ +L++H +++ +LF DI+DG LI LLEVLSG + E+G +K++H+++N+ AL +L R+IKLVNIN +DI +G+P IVLGLIW IIL+FQI+E H + + +V + A + + + K LL W+Q + + + DFG SW +GIAFH++I P+LVDM I + + ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTY++QFL
Sbjct: 8 TLNQYVISFLQRHPP-MVINELFEDIKDGTKLIALLEVLSGQKLPCEQGRQLKRIHWVANIGAALKFLEGRRIKLVNINSTDIADGRPSIVLGLIWTIILYFQIEELTSNLPQLHAMSSSTSSVDSVVSSEAASPPIKRKIVNKIQGSAKKALLRWVQYTAAKRLGIEVKDFGPSWRNGIAFHSVIYAIRPDLVDMDIEKLKRRTNRENLEEAFSIAENELGIPRLLDPEDVDVDKPDEKSIMTYIAQFL 256
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Syne1 (spectrin repeat containing, nuclear envelope 1 [Source:MGI Symbol;Acc:MGI:1927152]) HSP 1 Score: 202.216 bits (513), Expect = 2.497e-53 Identity = 121/266 (45.49%), Postives = 174/266 (65.41%), Query Frame = 1
Query: 142 IGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
I N++++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G +K++H ++N+ AL +L RKIKLVNIN +DI +G+P IVLGL+W IIL+FQI+E +L S + +V + +AS K LL W+Q+ ++ + + DFGKSW +G+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 14 ITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 279
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Syne1 (spectrin repeat containing, nuclear envelope 1 [Source:MGI Symbol;Acc:MGI:1927152]) HSP 1 Score: 196.438 bits (498), Expect = 5.468e-49 Identity = 121/273 (44.32%), Postives = 174/273 (63.74%), Query Frame = 1
Query: 142 IGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERK-------IKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
I N++++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G +K++H ++N+ AL +L RK IKLVNIN +DI +G+P IVLGL+W IIL+FQI+E +L S + +V + +AS K LL W+Q+ ++ + + DFGKSW +G+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 14 ITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 286
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Syne1 (spectrin repeat containing, nuclear envelope 1 [Source:MGI Symbol;Acc:MGI:1927152]) HSP 1 Score: 197.593 bits (501), Expect = 5.963e-49 Identity = 121/273 (44.32%), Postives = 174/273 (63.74%), Query Frame = 1
Query: 142 IGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERK-------IKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
I N++++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G +K++H ++N+ AL +L RK IKLVNIN +DI +G+P IVLGL+W IIL+FQI+E +L S + +V + +AS K LL W+Q+ ++ + + DFGKSW +G+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 14 ITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 286
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Macf1 (microtubule-actin crosslinking factor 1 [Source:MGI Symbol;Acc:MGI:108559]) HSP 1 Score: 165.236 bits (417), Expect = 1.555e-43 Identity = 113/254 (44.49%), Postives = 155/254 (61.02%), Query Frame = 1
Query: 166 KDEQDFIQKKTFTKWINKYL---KKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPES 918
+DE+D +QKKTFTKW+NK+L +KH + DL+ D+RDG LI LLEVLSG + +E+G + H L NV+IAL++L +R++KLVNI DI +G P + LGLIW IIL FQI + + S +SG D K KLL W Q + + T+F WS G F+ALI + P+LVDM+ V ++NL+ AF++AER LG+ +LLD+EDV PDEKS++TYVS + PE
Sbjct: 17 RDERDRVQKKTFTKWVNKHLMKVRKH-----INDLYEDLRDGHNLISLLEVLSGIKLPREKG--RMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIYI---SGESG------------DMSAKEKLLLWTQKVTAGYTGVKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQVQSNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEG 247
BLAST of Nesprin-1 vs. Ensembl Mouse
Match: Plec (plectin [Source:MGI Symbol;Acc:MGI:1277961]) HSP 1 Score: 170.244 bits (430), Expect = 2.557e-42 Identity = 115/271 (42.44%), Postives = 160/271 (59.04%), Query Frame = 1
Query: 118 TVVGNIMQIGNII------RKYKDEQD---FIQKKTFTKWINKYLKKH---DSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLE 894
VVG+++ + + R+ KDEQD +QKKTFTKW+NK+L KH ++ + DL+ D+RDG LI LLEVLSG ++ +E+G + H L NV+IAL+YL R++KLVNI DI +G P + LGLIW IIL FQI + ++ +S+ D K KLL W Q ++ + +F SW G F+A+I P L+DM V + +NLD AF +AER LG+ +LLD EDV +PDEKSI+TYVS +
Sbjct: 12 VVVGHVVTLAAVWHWRKGHRQAKDEQDERDRVQKKTFTKWVNKHLIKHWRAEAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKG--RMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSE---------------DMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYD 265
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q6ZWR6|SYNE1_MOUSE (Nesprin-1 OS=Mus musculus OX=10090 GN=Syne1 PE=1 SV=2) HSP 1 Score: 204.527 bits (519), Expect = 3.832e-50 Identity = 121/266 (45.49%), Postives = 174/266 (65.41%), Query Frame = 1
Query: 142 IGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
I N++++ +DEQ+ +QK+TFTKWIN +L K ++V DLF D++DG+ L+ LLEVLSG + E+G +K++H ++N+ AL +L RKIKLVNIN +DI +G+P IVLGL+W IIL+FQI+E +L S + +V + +AS K LL W+Q+ ++ + + DFGKSW +G+AFH++I P LVD++ V ++NL+ AF IAE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 14 ITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 279
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q6ZWQ0|SYNE2_MOUSE (Nesprin-2 OS=Mus musculus OX=10090 GN=Syne2 PE=1 SV=2) HSP 1 Score: 167.933 bits (424), Expect = 3.671e-39 Identity = 116/327 (35.47%), Postives = 165/327 (50.46%), Query Frame = 1
Query: 115 PTVVG-NIMQIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXX------XXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDK-------------GVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKL 1035
PT G + I ++ + EQ+ QKKTFT WIN L KH +V DLF DI+ G +L+ LLEVLSG + +++G N + N++ AL +L R IKL+NI+ +DIVEG P I + L + I Q + ++ S + +V ++ +S K K LL W Q R ++ +TDF SW +G+AF A+I P+L+DM + + NL AF IAE L I KLL+ EDV PDEKSIMTYV+QFL K P P S + V D + + ++E R +K+
Sbjct: 8 PTEDGEGFLGIDDLHFSLQAEQEDTQKKTFTCWINSQLAKHTPPSVVSDLFADIKKGHVLLDLLEVLSGQQLPRDKGSNTFQCRI--NIEHALTFLKNRSIKLINIHVADIVEGNPSIILGLIWTIILHFHIEKLAQTLSCDYNQPSPEVVSVAASSPTSSPPTKKCSKAQAQARWQWSAKKALLQWAQEQCARSESVNVTDFKSSWRNGMAFLAVIHALRPDLIDMDSMRHRSNKDNLKEAFRIAEHELKIPKLLEPEDVDVVNPDEKSIMTYVAQFL------------KYSKDAPGPGDSTQAKVRDAL--VWLTLQEKRFQKM 318
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|D3ZHV2|MACF1_RAT (Microtubule-actin cross-linking factor 1 OS=Rattus norvegicus OX=10116 GN=Macf1 PE=1 SV=1) HSP 1 Score: 167.162 bits (422), Expect = 6.641e-39 Identity = 109/256 (42.58%), Postives = 151/256 (58.98%), Query Frame = 1
Query: 160 KYKDEQDFIQKKTFTKWINKYL---KKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPES 918
+ DE+D +QKKTFTKW+NK+L +KH + DL+ D+RDG LI LLEVLSG + +E+G + H L NV+IAL++L +R++KLVNI DI +G P + LGLIW IIL FQ + + + D K KLL W Q + + T+F WS G F+ALI + P+LVDM+ V ++NL+ AF++AER LG+ +LLD+EDV PDEKS++TYVS + PE
Sbjct: 71 RVADERDRVQKKTFTKWVNKHLMKVRKH-----INDLYEDLRDGHNLISLLEVLSGIKLPREKG--RMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ---------------ISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEG 303
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q9QXS1|PLEC_MOUSE (Plectin OS=Mus musculus OX=10090 GN=Plec PE=1 SV=3) HSP 1 Score: 167.162 bits (422), Expect = 6.688e-39 Identity = 113/262 (43.13%), Postives = 155/262 (59.16%), Query Frame = 1
Query: 118 TVVGNIMQIGNIIRKYKDEQDFIQKKTFTKWINKYLKKH---DSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLE 894
T VG + + G DE+D +QKKTFTKW+NK+L KH ++ + DL+ D+RDG LI LLEVLSG ++ +E+G + H L NV+IAL+YL R++KLVNI DI +G P + LGLIW IIL FQI + ++ +S+ D K KLL W Q ++ + +F SW G F+A+I P L+DM V + +NLD AF +AER LG+ +LLD EDV +PDEKSI+TYVS +
Sbjct: 164 TTVGTLARPGPEPAPATDERDRVQKKTFTKWVNKHLIKHWRAEAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKG--RMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSE---------------DMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYD 408
BLAST of Nesprin-1 vs. UniProt/SwissProt
Match: sp|Q9UPN3|MACF1_HUMAN (Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4) HSP 1 Score: 166.777 bits (421), Expect = 8.334e-39 Identity = 109/258 (42.25%), Postives = 152/258 (58.91%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYL---KKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPES 918
+ + DE+D +QKKTFTKW+NK+L +KH + DL+ D+RDG LI LLEVLSG + +E+G + H L NV+IAL++L +R++KLVNI DI +G P + LGLIW IIL FQ + + + D K KLL W Q + + T+F WS G F+ALI + P+LVDM+ V ++NL+ AF++AER LG+ +LLD+EDV PDEKS++TYVS + PE
Sbjct: 69 VVRVADERDRVQKKTFTKWVNKHLMKVRKH-----INDLYEDLRDGHNLISLLEVLSGIKLPREKG--RMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ---------------ISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAER-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKVPEG 303
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A267EWS2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031215g1 PE=4 SV=1) HSP 1 Score: 257.684 bits (657), Expect = 2.418e-64 Identity = 319/1192 (26.76%), Postives = 531/1192 (44.55%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLK------LLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKL--------SMPEPAK-SNERGVND---------KIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLL---------LDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILE--FHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHK----IASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDI----EKLLSAD-----PTFKE---WAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNST-----------DDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHEN--KSLHVDNL---RKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEI---ERELAEMLTNFQSKANQQQ----EMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFA-LLVSKKIQE---SSWLTPF------KSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDS---------------MRIALDEILLKIQESDDD-------ELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQE----IIYKHNVYFEECDFKVTSLSYLSEMK---TLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLS 3390
++ +DEQ+ +QKKTFT WIN YL + + DLF +++DG+ L+ LLEVLSG + E M+++H LSNV+ AL++L +KIKLVNINP+DIV+GKP IVLGLIW IIL+FQI+E E + ++ +++G K K LL W QN + +Y + I DFG SW G AF+A++ +P+LVDM+ + ++NL++AF AE L I +L+D EDV +KPDEKSIMTYV+QFL+ PE +KK KL S E AK + E+ ND ++R + + R + ++ + F + + + LK E + + + G LL L+ ++AA + +W LD ++ + WL +ER L F + + I+ L LT E+ F ++P E ++ + ++RR+ +V ++E +RQKL L +A + E+ KL W + L E L D+++ + G + V + ++ E L D P +E +A E + RE++ L+ E W + + W+ S D F + +R ++ + L+ + + + + ++L+ IN + E +S +D RK Y + WL+++E L ++ + + E + L + E ++ +FK +SK Q + + ++ MLG LKI K RL L R +L ++ L +L +SL + +++ V I ER LA+ + + K +++ + G+IN + K + LT +K S KV N + A+ E LN R F LL + + E +WL KS L W+ E LA D N L++S+A S A +++L + ES D ++ E L+++FN I LSEA + R R+ + C + + T D E+ L + +E I+ H YF + ++ L+EM+ + + A + E L + E L R+ + + E+ L E + N+L+ + S+ D +
Sbjct: 11 VKNLRDEQERVQKKTFTNWINTYLIQCQPPCKIADLFPEVKDGIKLLLLLEVLSGQKLPHESRKVMQRVHCLSNVRTALSFLESKKIKLVNINPADIVDGKPSIVLGLIWTIILYFQIEEQE--------DTIMKSLEGTELAERGEKFKGSAKKALLAWAQNNLGDKYAIDIRDFGNSWRDGSAFNAMVHNIDPSLVDMEKLGDRTNRENLEAAFAAAESGLNIPRLIDPEDVDVDKPDEKSIMTYVAQFLK---AYPEGSKKKPKLLEQIEDAQSKVEAAKQAAEQERNDLRKISDFCEAVERELPTSGKGRGDPVENYKKFEEFRQQQAALKEAYEALL---KRRADGHLLTLKPDEVDALEAQWRAASDQLNEWRWQLDSALPGDLGKVGGWLARAERCLREPFPDTAAGEPDEAIAQALHQRLT----EHRAIFADAPAMRKAFQEARKSA-----GRGLPAEQLADIDRRLTQVQQDEPEVRQKLEFLESKYRVLAYFIVTER----KLPEWTGNYGHLPEVEALLADYDNFVVAGKLLPSVDQALDSFRQQAEALKKRDSGKSMPETRENDRFATEATRKWDRLRREVQAAPEPLKRIAESWKQFLDEAEAIESWLPSAQAALRGSAEERDSFFADFANWEARHRRLNDAG---GLLTANCAPAAADEVRQRLQRINRQWKELSEGHKQSERMDAAEKSRKGYHASTTALTDWLDRAEQLVEAELPCNVRCIRENLASLQATQDQQEPMEAEFKSVSKTAQSMVKDLPEQTVNEMLGNLKIIKDRLQNL---RKRLPERSRGLKSVLPNVESLENGLEELVSWIEAGERLLAQHGGDSEDKTIEEKIEAHKTHFGQINYFKSVLDGKNRFLTKIK-------SSKVKNLNTDEVDAQ----FEDLN--RRFKDLLAASRSWERRLDAWLRRLDAYEKKKSELTAWLGEAGGALA------QDDAN--LDDSIARHRSFFDSNQQKQRQLLTNFLTASNDLLNSLTESGDGGATELARRIEAETQQLEADFNDI---LSEAPN-RLLRLTLDSCDAKLNQLLT--DGEDALASFNQRVEAKEPLDRILKNHETYFFKSHYRQNCEQLLNEMRQADVIAGAAARIDAQTDRFETLWQAAESLRTRLKDLPAKWKLFEDRLHEIQAFAEHSNDLLDRLAGLESSPDTA 1142
BLAST of Nesprin-1 vs. TrEMBL
Match: R7T5N2 (Uncharacterized protein (Fragment) OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_118770 PE=4 SV=1) HSP 1 Score: 258.455 bits (659), Expect = 5.209e-64 Identity = 313/1202 (26.04%), Postives = 555/1202 (46.17%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE--HELDKKSQQS------------GAVRQANANNSASDK---GVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKES----------RIEKLKQIENFNDVFKLISNLKNELELIPEWDQ---TSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEF-------HKNNQIDVSKEIS--PELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQ----YWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSAD---PTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVD----WMNSTDDFSISPQEYISR--------KHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHV-----DNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIES-----LKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESS-------W--LTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALD--------EILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYR----KFRILENKCIEFIKNIETQ----LDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENF----PKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLD-LSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVA 3480
DEQ+ +QKKTFT WIN YL + D +++LF DI+DG L+ LLEVLSG + E+GP +K+LH++SN+ AL++L ++IKLVNIN +D+V+GKP IVLGL+W IIL+FQI+E L ++SQ + GA A + SA DK G K +L W Q + + + + + DFG+SW SG+AF+A++ P+L+DM + Q + NL++AFD AE+HLGI +LLDSEDV +KPDEKSIMTYV+QFLE P++ + + S +R ND ++ ++ +E+ R ++ KQ F + K + + LE D + ++ Q + + + QW LD ++ + WL +E ++E H++ ++ ++ DL KE+ + NS + L R I +D N + F + T + ++++ EE R LL +A K+K + Q +++ + + ++ +++ + A V + D + + AD + + +++++ ++ EI ++T L +E W + Y+ VD W+ + P E + + K+ +++ FL E + + + ++ +I+ + ++++ + R+EY + +E ++ WL +E L + + +++ L E ++ FK +S+ Q + + + ML LK K RL++L D P+ +K L SL + ++ +S++ Q + ER L + G INV + + + + Y + +ES KVS K + E + N R + + S K E+ W L LE W++E LA D++N L+ + A D++ +D E+L + E D +EL+ L + +I E R +F++ E EF++NIET +++ L + N I+EI+ KH V F+E T L L EM T + + P++ + E R+ E+L I+ + L E + +E +K + + V + L + +++++Y L+KF +I ++D ++ A
Sbjct: 1 DEQERVQKKTFTNWINSYLLRRDPPCRIEELFEDIKDGTKLLMLLEVLSGEKLAMEKGPRLKRLHFISNISTALSFLESKRIKLVNINSTDVVDGKPAIVLGLVWTIILYFQIEEFTKSLAQQSQHTPMSSTSSLGSHDGAT-PAKKSRSALDKFKGGAKKMMLGWAQKAVTKRFGIEVKDFGRSWRSGLAFNAMVHNVRPDLIDMNSLAQNPNRVNLENAFDCAEKHLGIPRLLDSEDVDVDKPDEKSIMTYVAQFLE-KYPDPDA-------DVTDSGDSKQRHYNDLLE-WLTQAEETLSIVDLPVNDRQQEYKQYMTFTEELKTKTKMYERLEKHGNDDSFLTLTQEKWTVVRQRWTSVTQQTRIWQWKLDSNLPGQLGYIGDWLYRAEEMVESEIQYVDKHEDTATNIKMKLDELKGFFQDLEQIKKEFHSIKGNSTYEGVVLP---RSQI-SDMNLR-FQTLTKKSDTMVRRLEYEEMQYR--LLAFLVVAEAKLKAWTVKCGRQDEVEALCKDYMNFVHEQELFKEYDKTYQDCKRRADVHKR-QDPQNTVEADRVNKSLDDITEKWRH----LKVEISSVQTMLEEVVEYWKR----YHACVDLFHVWLGDAEQMLKKPPEERADFFENLDKWEEKLQVLKEASNFLVEAVDEPIAQEVKEQVLFIDRRWHDVQGQVTVYLSKQTTEKSRQEYSVGLETMQNWLRNAEELLKKKPQSTHGEIRKHLTQLDSILAEEEQLEAQFKVVSRTAQSLVKDSDQATIREMLELLKACKQRLVSLQRDVPEKLKPLKSLMAQVESLENGISDLSQWLDSGERLLDSHRID-------------GNINVVEDRLVAHKDHFKETTYYKSMLESKNKVYQKVSKNGTKHLQISSLEEVMVEINKRFQSCVTSSKDWENRLEKGLRLWRNLQSKAQPLEEWVQEAEVVLA----QGGDNINDLIASHRAFFDTVDSQMDSDFTRAGQELLAVLAEEDCEELETSMGVLHDKQKEI----LEFAPIRLIKLQFQLPEE---EFLQNIETAEKTLAQQKQALEQKGN---IKEILRKHKVIFQESGLSRTCLQCLEEMATCVHDLQQRQPEHLGLQEAYEDHVRRWENLRLEIEALRVQL---EEVPQRWQEYNTKRDAFISWMGTVEETIQRLEEQTLSTNEYKETLDKFQEVIRNIDQHRDDA 1146
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A1I8GMD0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 247.284 bits (630), Expect = 8.785e-63 Identity = 232/806 (28.78%), Postives = 392/806 (48.64%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKG------VKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPES----PRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELE-LIP---EWDQTSSTGDLL----LDQD-----FKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYT--ISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEK----LLSADPTFKEWAQEF----KYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWM-NSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSS--------------DSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVD 2427
++ +DEQ+ +QKKTFT WIN YL + DLF +I+DG L+ LLEVLSG+ ++KE NM+++H LSNV+ AL++L ++IKLVNINP+DIV+GKP IVLGL+W IIL+FQI+E E +R++ +++G K LL W QN + +Y++ + DFG SW G AF+A++ +P+LVDM + ++NL++AF AE L I +LLD+EDV +KPDEKSIMTY++QFL+ PE P+ + +L A ER D I F V + E N ++ ++ L+ E + L P + + S G LL D D ++ A + +W LD + + + +WL +E L + D + + E +L+ +++E+ F P ++R + + +S +++ R+ +V+ +E +R++L L L + KL W + ED D+ + + +G V V + ++ + K + DP+ A F + ++R+++ L I W L E DW+ ++ +P E I + E ++ L+E +S + ++T+ R+ + + +F + + SL + R++Y ++ WL++SE L ++ S + V E + + E E ++ +FK LSK Q +++ K + ML LK + RL + R L +K L IL + ++L S +D
Sbjct: 10 VKSLRDEQERVQKKTFTNWINTYLITCQPPCKISDLFTEIKDGTRLLLLLEVLSGNKLQKENRGNMQRVHCLSNVRTALSFLESKQIKLVNINPADIVDGKPTIVLGLMWTIILYFQIEEQE--------DMIRKSLEGTELAERGELFKGSAKKALLAWAQNNLGDKYDVDLKDFGSSWRDGAAFNAMVHNIDPSLVDMDALRSRSNRENLEAAFQAAENGLNIPRLLDAEDVDVDKPDEKSIMTYIAQFLK---AYPEGGKNRPKLQDQLDAARQAGEKERLDLDSINDFCRKV---------ESEAPNGDYQTLAELQAERDNLQPSVEDLAKRSKDGRLLSTPPADVDAALAAWRQADDQLRKLRWRLDAELPGDFGRIGQWLGRAEACL-YQDWPADDAPDDSAAE---ELSERLREHNEVFSEDP------QSVRRDLQAARRAPPAGVSDAQIANMDTRLGRVIADEPDVRRRLEFLEPKRRLLASLAQCERKLPLWTGKCGKQQEVEDLFSDYNAFVIDGKLVDGVEQALDSLRKQAEPMRKRDPSGSREADRFLSDTRKRWDKVKRDVQGAGGPLEKAISCWKTYSRLSVEFNDWLPDAEQALRSTPDERDRFFADIRKRESDMRELNEAASYLTGCCVEPVASEIRTQQQTIGRRWKALFEDFKKTEKLDSLERN--RRDYHDGSGRLRDWLDRSETLADAEVACSREKVKESLDQIQELVDQQEAMEGEFKTLSKAAQDMAKELPKASLDEMLASLKEARERLQKV---RRSLPEKGRGLRGILPQIETLESGLD 780
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A267EZS9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015905g1 PE=4 SV=1) HSP 1 Score: 252.292 bits (643), Expect = 1.461e-62 Identity = 265/960 (27.60%), Postives = 445/960 (46.35%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLK------LLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKL--------SMPEPAKSNERGVND---KIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLL---------LDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILE--FHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHK----IASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDI----EKLLSAD-----PTFKE---WAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNST-----------DDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHEN--KSLHVDNL---RKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEI---ERELAEMLTNFQSKANQQQ----EMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRL---ETWIEETTSNLAILKNLETDSVNSL 2823
++ +DEQ+ +QKKTFT WIN YL + + DLF +++DG+ L+ LLEVLSG + E M+++H LSNV+ AL++L +KIKLVNINP+DIV+GKP IVLGLIW IIL+FQI+E E + ++ +++G K K LL W QN + +Y + I DFG SW G AF+A++ +P+LVDM+ + ++NL++AF AE L I +L+D EDV +KPDEKSIMTYV+QFL+ PE +KK KL E +++ R ++D ++R + + R + ++ + F + + + LK E + + + G LL L+ ++AA + +W LD ++ + WL +ER L F + + I+ L LT E+ F ++P E ++ + ++RR+ +V ++E +RQKL L +A + E+ KL W + L E L D+++ + G + V + ++ E L D P +E +A E + RE++ L+ E W + + W+ S D F + +R ++ + L+ + + + + ++L+ IN + E +S +D RK Y + WL++++ L ++ + + E + L + E ++ +FK +SK Q + + ++ MLG LKI K RL L R +L ++ L +L +SL + +++ V I ER LA+ + + K +++ + G+ N + K + LT +K S KV N + A+ E LN R F L+S+ QE+ + +S L + W+ L L + E SL
Sbjct: 11 VKNLRDEQERVQKKTFTNWINTYLIQCQPPCKIADLFPEVKDGIKLLLLLEVLSGQKLPHESRKVMQRVHCLSNVRTALSFLESKKIKLVNINPADIVDGKPSIVLGLIWTIILYFQIEEQE--------DTIMKSLEGTELAERGEKFKGSAKKALLAWAQNNLGDKYAIDIRDFGNSWRDGSAFNAMVHNIDPSLVDMEKLGDRTNRENLEAAFAAAESGLNIPRLIDPEDVDVDKPDEKSIMTYVAQFLK---AYPEGSKKKPKLLEQVEAAKQAAEQERNDLRKISDFCEAVERELPTSGKGRGDPVENYKKFEEFRQQQAALKEAYEALL---KRRADGHLLTLKPDEVDALEAQWRAASDQLNEWRWQLDSALPGDLGKVGGWLARAERCLREPFPDTAAGEPDEAIAQALHQRLT----EHRAIFADAPAMRKAFQEARKSA-----GRGLPAEQLADIDRRLTQVQQDEPEVRQKLEFLESKYRVLAYFIVTER----KLPEWTGNYGHLPEVEALLADYDNFVVAGKLLPSVDQALDSFRQQAEALKKRDSGKSMPETRENDRFATEATRKWDRLRREVQAAPEPLKRIAESWKQFLDEAEAIESWLPSAQAALRGSAEERDSFFADFANWEARHRRLNDAG---GLLTANCAPAAADEVRQRLQRINRQWKELSEGHKQSERMDAAEKSRKGYHASTTALTDWLDRAKQLVEAELPCNVRCIRENLASLQATQDQQEPMEAEFKSVSKTAQSMVKDLPEQTVNEMLGNLKIIKDRLQNL---RKRLPERSRGLKSVLPNVESLENGLEELVSWIEAGERLLAQHGGDSEDKTIEEKIEAHKTHFGQTNYFKSVLDGKNRFLTKIK-------SSKVKNLNTDEVDAQ----FEDLN--RRFKALLSRAEQEAQDMQAAQSSLKLAKDWLRTAGDRLEPLTSTEAGDKASL 924
BLAST of Nesprin-1 vs. TrEMBL
Match: A0A267F524 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010703g1 PE=4 SV=1) HSP 1 Score: 248.825 bits (634), Expect = 2.063e-61 Identity = 232/806 (28.78%), Postives = 392/806 (48.64%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKG------VKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPES----PRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELE-LIP---EWDQTSSTGDLL----LDQD-----FKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYT--ISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEK----LLSADPTFKEWAQEF----KYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWM-NSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSS--------------DSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVD 2427
++ +DEQ+ +QKKTFT WIN YL + DLF +I+DG L+ LLEVLSG+ ++KE NM+++H LSNV+ AL++L ++IKLVNINP+DIV+GKP IVLGL+W IIL+FQI+E E +R++ +++G K LL W QN + +Y++ + DFG SW G AF+A++ +P+LVDM + ++NL++AF AE L I +LLD+EDV +KPDEKSIMTY++QFL+ PE P+ + +L A ER D I F V + E N ++ ++ L+ E + L P + + S G LL D D ++ A + +W LD + + + +WL +E L + D + + E +L+ +++E+ F P ++R + + +S +++ R+ +V+ +E +R++L L L + KL W + ED D+ + + +G V V + ++ + K + DP+ A F + ++R+++ L I W L E DW+ ++ +P E I + E ++ L+E +S + ++T+ R+ + + +F + + SL + R++Y ++ WL++SE L ++ S + V E + + E E ++ +FK LSK Q +++ K + ML LK + RL + R L +K L IL + ++L S +D
Sbjct: 10 VKSLRDEQERVQKKTFTNWINTYLISCQPPCKISDLFTEIKDGTRLLLLLEVLSGNKLQKENRGNMQRVHCLSNVRTALSFLESKQIKLVNINPADIVDGKPTIVLGLMWTIILYFQIEEQE--------DMIRKSLEGTELAERGELFKGSAKKALLAWAQNNLGDKYDVDLKDFGSSWRDGAAFNAMVHNIDPSLVDMDALRSRSNRENLEAAFQAAENGLNIPRLLDAEDVDVDKPDEKSIMTYIAQFLK---AYPEGGKNRPKLQDQLDAARQAGEKERLDLDSINDFCRKV---------ESEAPNGDYQTLAELQAERDNLQPSVEDLAKRSKDGRLLSTPPADVDAALAAWRQADDQLRKLRWRLDAELPGDFGRIGQWLGRAEACL-YQDWPADDAPDDSAAE---ELSERLREHNEVFSEDP------QSVRRDLQAARRAPPAGVSDAQIANMDTRLGRVIADEPDVRRRLEFLEPKRRLLASLAQCERKLPLWTGKCGKQQEVEDLFSDYNAFVIDGKLVDGVEQALDSLRKQAEPMRKRDPSGSREADRFLSDTRKRWDKVKRDVQGAGGPLEKAISCWKTYSRLSVEFNDWLPDAEQALRSTPDERDRFFADIRKRESDMRELNEAASYLTGCCVEPVASEIRTQQQTIGRRWKALFEDFKKTEKLDSLERN--RRDYHDGSGRLRDWLDRSETLADAEVACSREKVKESLDQIQELVDQQEAMEGEFKTLSKAAQDMAKELPKASLDEMLASLKEARERLQKV---RRSLPEKGRGLRGILPQIETLESGLD 780
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000036923.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:24166584:24185412:1 gene:ENSAMXG00000043596.1 transcript:ENSAMXT00000036923.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 195.282 bits (495), Expect = 2.832e-52 Identity = 127/318 (39.94%), Postives = 187/318 (58.81%), Query Frame = 1
Query: 148 NIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERK-------IKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEK 1032
+I + +EQ+ +QK+TFTKWIN +L K + L + DLF DI+DG+ L+ LLEVLSG + E+G +K++H++SN+ AL +L R+ IKLVNIN +DI +G+P IVLGL+W IIL+FQI+E L S + +V ++ +AS K LL W+Q + + + DFG SW +G+AFH++I P+LVDM++V + ++NL+ AF +AE LGI +LLD EDV +KPDEKSIMTYV+QFL+ P+P +S G +++ +NV R E+
Sbjct: 5 SIKSRCPNEQESVQKRTFTKWINSHLAKRNPPLEINDLFEDIKDGVKLLALLEVLSGQRLPSEQGRQLKRIHWVSNIGTALKFLEGRRSVYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSNSASSVDSMASSETASPPMKRKVVTKFQGNAKRALLRWVQCTATKRLGIEVKDFGSSWRTGVAFHSVIYAIRPDLVDMELVKRRSNRENLEEAFTVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLK---------------HYPDPHQSETDGQQEEVLNSSLNVFVQREER 307
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000039764.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:24167966:24185412:1 gene:ENSAMXG00000043596.1 transcript:ENSAMXT00000039764.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 194.512 bits (493), Expect = 3.929e-52 Identity = 126/310 (40.65%), Postives = 183/310 (59.03%), Query Frame = 1
Query: 172 EQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERK-------IKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEK 1032
EQ+ +QK+TFTKWIN +L K + L + DLF DI+DG+ L+ LLEVLSG + E+G +K++H++SN+ AL +L R+ IKLVNIN +DI +G+P IVLGL+W IIL+FQI+E L S + +V ++ +AS K LL W+Q + + + DFG SW +G+AFH++I P+LVDM++V + ++NL+ AF +AE LGI +LLD EDV +KPDEKSIMTYV+QFL+ P+P +S G +++ +NV R E+
Sbjct: 10 EQESVQKRTFTKWINSHLAKRNPPLEINDLFEDIKDGVKLLALLEVLSGQRLPSEQGRQLKRIHWVSNIGTALKFLEGRRSVYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSNSASSVDSMASSETASPPMKRKVVTKFQGNAKRALLRWVQCTATKRLGIEVKDFGSSWRTGVAFHSVIYAIRPDLVDMELVKRRSNRENLEEAFTVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLK---------------HYPDPHQSETDGQQEEVLNSSLNVFVQREER 304
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: ENSAMXT00000045503.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:24166584:24193162:1 gene:ENSAMXG00000043596.1 transcript:ENSAMXT00000045503.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 195.667 bits (496), Expect = 8.638e-49 Identity = 119/271 (43.91%), Postives = 171/271 (63.10%), Query Frame = 1
Query: 148 NIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERK-------IKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSAS-----------DKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFL 891
+I + +EQ+ +QK+TFTKWIN +L K + L + DLF DI+DG+ L+ LLEVLSG + E+G +K++H++SN+ AL +L R+ IKLVNIN +DI +G+P IVLGL+W IIL+FQI+E L S + +V ++ +AS K LL W+Q + + + DFG SW +G+AFH++I P+LVDM++V + ++NL+ AF +AE LGI +LLD EDV +KPDEKSIMTYV+QFL
Sbjct: 5 SIKSRCPNEQESVQKRTFTKWINSHLAKRNPPLEINDLFEDIKDGVKLLALLEVLSGQRLPSEQGRQLKRIHWVSNIGTALKFLEGRRSVYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSNSASSVDSMASSETASPPMKRKVVTKFQGNAKRALLRWVQCTATKRLGIEVKDFGSSWRTGVAFHSVIYAIRPDLVDMELVKRRSNRENLEEAFTVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFL 275
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: MACF1 (microtubule actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]) HSP 1 Score: 166.007 bits (419), Expect = 2.960e-41 Identity = 107/256 (41.80%), Postives = 154/256 (60.16%), Query Frame = 1
Query: 160 KYKDEQDFIQKKTFTKWINKYL---KKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPES 918
+ DE+D +QKKTFTKW+NK+L +KH + DL+ D+RDG LI LLEVLSG + +E+G + H L NV+IAL++L +R++KLVNI DI +G P + LGLIW IIL FQ + + + + D K KLL W Q + ++F SWS+G F+AL+ + P+L+DM++V + ++NL+ AF+IAE LG+ +LLD+EDV PDEKS++TYVS + PE
Sbjct: 62 RVADERDRVQKKTFTKWVNKHLIKVRKH-----ITDLYEDLRDGHNLISLLEVLSGVQLPREKG--RMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQ---------------ISEIYVSGESGDLTAKEKLLLWTQQATEGYPGLRCSNFSSSWSNGRMFNALLHRYRPDLIDMEVVARQSNRENLEQAFEIAES-LGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAFPKIPEG 294
BLAST of Nesprin-1 vs. Ensembl Cavefish
Match: plecb (plectin b [Source:ZFIN;Acc:ZDB-GENE-100917-2]) HSP 1 Score: 169.088 bits (427), Expect = 2.135e-40 Identity = 108/240 (45.00%), Postives = 143/240 (59.58%), Query Frame = 1
Query: 163 YKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVS 882
+ DE+D +QKKTFTKW+NK+L K + V DL+ D+RDG LI LLEVLSG T+ +E+G + H L NV+IAL++L R++KLVNI DI +G P + LGLIW IIL FQ + N + D K KLL W Q ++ M +F SW G F+A+I P LVDM V + +NL+ AF++AE+ LG+ +LLD EDV PDEKSI+TYVS
Sbjct: 7 FPDERDRVQKKTFTKWVNKHLIKAQRH--VSDLYEDLRDGHNLISLLEVLSGETLPREKG--RMRFHKLQNVQIALDFLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ---------------ISDIQVNGQSDDMSAKEKLLLWSQRMVEGYQGMRCDNFTTSWRDGKLFNAVIHRHEPRLVDMSKVYRQTNLQNLEQAFNVAEKELGVTRLLDPEDVDVPHPDEKSIITYVS 227
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009426.1 (pep scaffold:Pmarinus_7.0:GL476614:383620:553344:1 gene:ENSPMAG00000008375.1 transcript:ENSPMAT00000009426.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 185.267 bits (469), Expect = 6.086e-46 Identity = 109/260 (41.92%), Postives = 146/260 (56.15%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKP--------------XXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIP----REYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLE 894
DEQ+ +QK+TFTKWIN +L L+V DLF D+RDG+ LI LLEVL+G + E+G +K++H LSN+ AL ++ R+IKLVNIN I +GKP I L+ + E L S A Q + K LL W+Q ++P R I DFG SW +GIAFH +I P LV+++ V Q +NL+ AF +AE LGI +LLD +DV +KPDEK IMTYV+QFL+
Sbjct: 1 DEQEAVQKRTFTKWINSHLALVRPPLVVDDLFKDLRDGVKLIALLEVLTGERLPYEQGRQLKRIHALSNIGTALKFMEARRIKLVNINAPYIADGKPSIVLGLIWTIILYFQIEEATNNLLPISPWSSETSLSSMEGSSTASPQRKRRQTPMRSTAKKALLKWVQLVVPSLESRVGGTEIRDFGASWRTGIAFHLMIRAIQPELVNLEQVTQRSNHENLEEAFIVAEEKLGIPRLLDPKDVDVDKPDEKIIMTYVAQFLK 260
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002838.1 (pep scaffold:Pmarinus_7.0:GL477168:22072:87306:1 gene:ENSPMAG00000002584.1 transcript:ENSPMAT00000002838.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 163.31 bits (412), Expect = 2.126e-40 Identity = 109/252 (43.25%), Postives = 150/252 (59.52%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYL---KKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPE 915
DE+D +QKKTFTKW+NK+L +KH V D++ D+RDG LI LLEVLSG + +E+G + H L NV+IAL++L R+IKLVNI DI +G P + LGLIW IIL FQI + ++ +S+ D K +LL W Q ++ + +F SW G F+A+I P L+DMK V ++NL+ AF +AER +G+ +LLD EDV PDEKSI+TYVS ++ PE
Sbjct: 6 DERDRVQKKTFTKWVNKHLMKVRKH-----VNDMYEDLRDGHNLISLLEVLSGEKLPREKG--RMRFHRLHNVQIALDFLRLRQIKLVNIRSDDIADGNPKLTLGLIWTIILHFQIADIQVSGQSE---------------DMTAKDRLLLWSQRMVEGYPGIRCDNFTTSWRDGRLFNAIIHRHRPELIDMKRVAVRANRENLEQAFTVAERDMGVTRLLDPEDVDVPSPDEKSIITYVSSLYDVIPRMPE 235
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006515.1 (pep scaffold:Pmarinus_7.0:GL476558:286719:335794:-1 gene:ENSPMAG00000005865.1 transcript:ENSPMAT00000006515.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 151.754 bits (382), Expect = 4.277e-37 Identity = 94/240 (39.17%), Postives = 138/240 (57.50%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQF 888
DE+D +QKKTFTKWIN +L++ N + DL+ D+RDG LI LLE LSG + +E+G ++H++ N++I LNYL +++KLVNI DIV+G P + LGLIW IIL + Q +A + +LL W + + ++ +F SW G A++ P LVD++ V + ++NL+ A +AE LG+ +LLD EDV + PDEKSI+TYVS
Sbjct: 1 DERDRVQKKTFTKWINSHLQQVRMN--IGDLYEDLRDGQALISLLESLSGDCIIREKG--RLRVHHVQNIQIVLNYLQHQQVKLVNIRKEDIVDGNPKLTLGLIWTIILHY------------------QVSAGQVGGGTPGRERLLAWARLVAKDVPGLSCHNFSSSWRDGRLLCAIVHAHRPGLVDLEEVRRRGARQNLEEALSLAESELGVPRLLDPEDVDVDAPDEKSIITYVSAL 218
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006506.1 (pep scaffold:Pmarinus_7.0:GL476558:286440:335800:-1 gene:ENSPMAG00000005865.1 transcript:ENSPMAT00000006506.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 152.14 bits (383), Expect = 7.590e-37 Identity = 95/240 (39.58%), Postives = 142/240 (59.17%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQF 888
DE+D +QKKTFTKWIN +L++ N + DL+ D+RDG LI LLE LSG + +E+G ++H++ N++I LNYL +++KLVNI DIV+G P + LGLIW IIL + Q+ + N+S+ + +LL W + + ++ +F SW G A++ P LVD++ V + ++NL+ A +AE LG+ +LLD EDV + PDEKSI+TYVS
Sbjct: 3 DERDRVQKKTFTKWINSHLQQVRMN--IGDLYEDLRDGQALISLLESLSGDCIIREKG--RLRVHHVQNIQIVLNYLQHQQVKLVNIRKEDIVDGNPKLTLGLIWTIILHY------------QNASFAHIEGNHSSMQS--RERLLAWARLVAKDVPGLSCHNFSSSWRDGRLLCAIVHAHRPGLVDLEEVRRRGARQNLEEALSLAESELGVPRLLDPEDVDVDAPDEKSIITYVSAL 224
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004049.1 (pep scaffold:Pmarinus_7.0:GL476488:489896:554954:1 gene:ENSPMAG00000003699.1 transcript:ENSPMAT00000004049.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 152.525 bits (384), Expect = 1.269e-36 Identity = 99/240 (41.25%), Postives = 145/240 (60.42%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQF 888
DE++ +QKKTFTKW+N +L + + + DL+ D+RDG MLI LLEVLSG + K M ++H L NV+ AL +L E+++ L N+ DIV+G + LGLIW IIL FQIQ+ ++ + +S K K LL W Q N+ + +F SW G+AF+ALI P+L+D + DP N+ +AF++AE+ LG+ +LLD+ED+ E PDEKS++TYV +
Sbjct: 2 DEREEVQKKTFTKWVNSHLSR--VSCRIGDLYADLRDGRMLIKLLEVLSGERLPKPTKGKM-RIHCLENVEKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETE-------------DSREVKSAKDALLLWCQMKTAGYPNVRVHNFTTSWRDGLAFNALIHKHRPDLIDFDALDPADPYGNMQTAFNVAEQKLGLTQLLDAEDIAVEHPDEKSVITYVVTY 225
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO37406 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFT6]) HSP 1 Score: 162.925 bits (411), Expect = 5.330e-44 Identity = 109/260 (41.92%), Postives = 159/260 (61.15%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGA--VRQANANNS----------------ASDKGVKLK--LLTWIQNIIPREY--NMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVS 882
D+Q+ IQKKTFTKW+N YL K ++ V D+F +++DG L+ LLEVLSG +RKERG K+ H L+N+ +++L+E+K+KLVNI+P IV+G I+LGL+W+II +Q + + K+Q+S + R A+NS A+ K V+ + +L W + + N I DF SW +G AF +I F P+LV++ + + D NL AFD+A HL + KLL+ EDV EKPDEKSIMTY++
Sbjct: 7 DDQEKIQKKTFTKWMNFYLAKSKPSVQVDDIFTELQDGTKLLTLLEVLSGEKLRKERGN--KRPHQLANLGHVIDFLTEKKVKLVNIHPESIVDGNTTIILGLLWIIIHHYQSSKIAQNIKAQRSLSEKYRIVPASNSLVPCAFETISQIQGFYATKKKVRTRKFMLEWAKKATSKASGSNEAIKDFSTSWRTGQAFLQIIHSFRPDLVNIATIAERDNITNLTEAFDLAYTHLNVPKLLEPEDVDVEKPDEKSIMTYMA 264
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO41099 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5D1]) HSP 1 Score: 151.369 bits (381), Expect = 2.092e-37 Identity = 96/238 (40.34%), Postives = 143/238 (60.08%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVS 882
DE + QKKTFTKWIN L + +N+ V DLF D++DG +LI LLEVL+G +++ERG NM +LH+L+NV A+ L E I+L+NI+ +DIV+G + LGLIW +I F Q Q + + + V LL+W QN +++T+F SW G+AF+A+I + P+L ++ P N + AF +A LG+ LLD+EDV+ ++PD+KSI+ YV+
Sbjct: 2 DEHEGTQKKTFTKWINIQLSRAGNNVRVGDLFNDLKDGTILIALLEVLTGKKIKRERG-NM-RLHHLNNVNNAMMILEENDIRLINISNNDIVDGNHKMTLGLIWSVIAHF------------QLNFALQFLMDEEGTPEEV---LLSWCQNTTKGYKGVSVTNFTTSWRDGLAFNAVIHRYRPDLFSYDALVGSSPMSNCEHAFKVARDSLGVDSLLDAEDVVRDRPDKKSIIMYVT 222
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO29101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4L2]) HSP 1 Score: 139.428 bits (350), Expect = 9.023e-35 Identity = 90/248 (36.29%), Postives = 141/248 (56.85%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMR-KERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLE 894
I+ K+E+ F QKKTFTKW+N +L K S L V DLF D+ DG +LI LLE++SG + RG ++H + NV AL +L ++ +KL +I D+V+G + L +++ I ++ S Q + S K K LL W Q + ++ I +F SW +G+AF+AL+ P+L+D + + NL++AF +AE LGI +LLD+EDV +PD++S+MTYV+ + +
Sbjct: 14 IKTLKNERIFSQKKTFTKWVNSFLDKVRSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKF--RVHNIQNVNKALEFL-QKSVKLESIGAEDVVDGN-----ERLILGLIWMIILRFQIADISYQD--------DMSKERKSAKEALLLWCQRMTRGYPDVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAEEKLGITRLLDAEDVDCPRPDDRSVMTYVAAYYQ 245
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO42431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1C0]) HSP 1 Score: 146.362 bits (368), Expect = 4.605e-34 Identity = 98/245 (40.00%), Postives = 153/245 (62.45%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQF 888
I+ DE++ +QKKTFTKWIN +L++ + V +L+ D++DG LI LLEVLSG + K M+ +H L NV+ +L +L ++++ L N+ DIV+G I LGLIW IIL FQIQ+ ++ ++ + + + A LL W Q+ ++TIT+F SW G+AF+A+I P+L++ + + + D ++NL+ AF++AE LGI LLD+EDV + PDEKSI+TYV+ +
Sbjct: 15 IKVLADERERVQKKTFTKWINSHLQRVGAR--VNELYHDLQDGRKLILLLEVLSGEKLPKPSKGRMR-IHNLENVEKSLVFLKKQRVHLENVGAHDIVDGNQKITLGLIWTIILRFQIQDITIEGETTEKRSAKDA--------------LLLWCQSKTVGYVHVTITNFTTSWRDGLAFNAIIHRHRPDLIEFEKLTKADAEQNLEQAFEVAETQLGITPLLDAEDVNVDFPDEKSILTYVAAY 242
BLAST of Nesprin-1 vs. Ensembl Nematostella
Match: EDO49576 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP7]) HSP 1 Score: 134.035 bits (336), Expect = 7.653e-31 Identity = 95/248 (38.31%), Postives = 144/248 (58.06%), Query Frame = 1
Query: 154 IRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMR-KERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLE 894
I+ K+E+ F QKKTFTKW+N +L K S L V DLF D+ DG +LI LLE++SG + RG ++H + NV AL +L ++ +KL +I D+V+G ++LGLIW+IIL ++ S Q + S K K LL W Q + + I +F SW +G+AF+AL+ P+L+D + + NL++AF +A LGI +LLD+EDV +PD++S+MTYV+ + +
Sbjct: 14 IKTLKNERIFSQKKTFTKWVNSFLDK--SGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKF--RVHNIQNVNKALEFL-QKSVKLESIGAEDVVDGNERLILGLIWMIIL-----RFQIADISYQD--------DMSKERKSAKEALLLWCQRMTRGYPGVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAAEKLGITRLLDAEDVDCPRPDDRSVMTYVAAYYQ 243
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: ENSORLT00000033742.1 (pep primary_assembly:ASM223467v1:24:9030654:9050235:-1 gene:ENSORLG00000028886.1 transcript:ENSORLT00000033742.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 195.667 bits (496), Expect = 2.451e-50 Identity = 123/262 (46.95%), Postives = 170/262 (64.89%), Query Frame = 1
Query: 175 QDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXE-----HELDKKSQQSGAVRQANANNSASDKGVKLK------------LLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITR 909
Q+ +QK+TFTKWIN +L KH L VKDLF DI+DG+ML+ LLEVLSG + E+G +K++H+++N+ AL +L RKIKLVNIN +DIV+G+P IVLGL+W IIL++QI+E EL S + ++ + ++ + VK K LL W+Q + + + DFG SW +G+AF ALI PNLVDM+ V + ++NL AF +AE LGI +LLD EDV +KPDEKS+MTYV+QFL+ R
Sbjct: 19 QEAVQKRTFTKWINSHLAKHAPPLEVKDLFEDIKDGVMLLALLEVLSGQKLPCEQGKKLKRIHWVANIGTALKFLEGRKIKLVNINSTDIVDGRPSIVLGLVWTIILYYQIEELTSSLPELPLLSSSTSSMDSSTSSTDTTSPPVKRKPLPPVQGGARKALLRWVQQTSTKCLRLEVKDFGPSWRTGLAFFALINALRPNLVDMERVRRRSNRENLQEAFLLAETELGIPQLLDPEDVDVDKPDEKSVMTYVAQFLKYPPQR 280
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: ENSORLT00000000374.2 (pep primary_assembly:ASM223467v1:22:316712:329038:1 gene:ENSORLG00000000306.2 transcript:ENSORLT00000000374.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 182.956 bits (463), Expect = 1.881e-46 Identity = 140/397 (35.26%), Postives = 219/397 (55.16%), Query Frame = 1
Query: 172 EQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQS----GAVRQANANNSASDKGVKLK------------LLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSN----ERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELI-----PEWDQTSSTGDLLLDQ-------DFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERIL 1266
EQ+ +QK+TFTKWIN +L+K + DLF DI+DG+ L+ LLEVLSG + E+G ++K++H++SN+ AL +L RKIKLVNI+ +D+ +G+P IVLGLIW IIL+FQI+E + + Q+ + + ++ VK K LL W+Q + + + + DFG SW G+AF +++ P+LVDM+ V + ++NL+ AF +AE LGI +LLD EDV +KPDEKSIMTYV+QFL+ P P + + PA N ER + ++K F+ +++ + N +D +++ + + E+ P G L +DQ D +A+ +L LD+S+ ++ WL +E L
Sbjct: 5 EQEAVQKRTFTKWINSHLEK------MNDLFEDIKDGVKLLALLEVLSGQRLPCEQGRHLKRIHWVSNISTALKFLEGRKIKLVNIHATDVADGRPSIVLGLIWTIILYFQIEELTSNLPALQAFSNSSSSVDSLTSSETGSPPVKRKVLHKFQGNAKKVLLRWVQCTAAKHHGIEVKDFGPSWRDGVAFQSMVHAIRPDLVDMEEVRRRSNRENLEEAFSLAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLK-HYPNP-GPAAGQQEVLLWPADCNLTREERKMLRELKVFLDQLEKDVLRAQGSDGNLSDKYQVFKHFHVQFEMKKKQAEPLLQPVHPDGKLSVDQALVKQAWDHVSAR--LLDWHIHLDKSLPGPLGSIGAWLHRAEMAL 391
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: pleca (plectin [Source:NCBI gene;Acc:101160251]) HSP 1 Score: 176.407 bits (446), Expect = 1.241e-42 Identity = 112/272 (41.18%), Postives = 150/272 (55.15%), Query Frame = 1
Query: 148 NIIRKYKDEQDFIQKKTFTKWINKYLKKH----------------DSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPE 915
N+ KYKDE+D +QKKTFTKW+NK+L KH + + DL+ D+RDG LI LLEVLSG T+ +E+G + H L NV+IAL++L R++KLVNI DI +G P + LGLIW IIL FQ + N + D K +LL W Q ++ + +F SW G F A+I P L+DM V + Q+NL+ AF +AER LG+ +LLD EDV PDEKSI+TYVS + P+
Sbjct: 24 NVREKYKDERDRVQKKTFTKWVNKHLIKHWKAECFISLGVLRKQEEVQRHITDLYEDLRDGHNLISLLEVLSGETLPREKG--RMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ---------------ISDIQVNGQSDDMTAKERLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFSAIIHKHRPALIDMNQVYRQTNQENLEQAFSVAERELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPD 278
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: pleca (plectin [Source:NCBI gene;Acc:101160251]) HSP 1 Score: 172.94 bits (437), Expect = 1.129e-41 Identity = 108/252 (42.86%), Postives = 145/252 (57.54%), Query Frame = 1
Query: 169 DEQDFIQKKTFTKWINKYLKKH---DSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPE 915
DE+D +QKKTFTKW+NK+L KH + + DL+ D+RDG LI LLEVLSG T+ +E+G + H L NV+IAL++L R++KLVNI DI +G P + LGLIW IIL FQ + N + D K +LL W Q ++ + +F SW G F A+I P L+DM V + Q+NL+ AF +AER LG+ +LLD EDV PDEKSI+TYVS + P+
Sbjct: 15 DERDRVQKKTFTKWVNKHLIKHWKAEVQRHITDLYEDLRDGHNLISLLEVLSGETLPREKG--RMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ---------------ISDIQVNGQSDDMTAKERLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFSAIIHKHRPALIDMNQVYRQTNQENLEQAFSVAERELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPD 249
BLAST of Nesprin-1 vs. Ensembl Medaka
Match: plecb (plectin b [Source:ZFIN;Acc:ZDB-GENE-100917-2]) HSP 1 Score: 172.17 bits (435), Expect = 2.149e-41 Identity = 112/255 (43.92%), Postives = 149/255 (58.43%), Query Frame = 1
Query: 133 IMQIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLEL 897
I N+ KYKDE+D +QKKTFTKW+NK+L K + V DL+ D+RDG LI LLEVLSG T+ +E+G + H L NV+IAL++L R++KLVNI DI +G P + LGLIW IIL FQ + N + D K KLL W Q + + +F SW G F+A+I P L+DM V Q +NL+ AF++AE+ LG+ +LLD EDV PDEKSI+TYVS ++
Sbjct: 19 IQAYENVREKYKDERDRVQKKTFTKWVNKHLIKAQRH--VTDLYEDLRDGHNLISLLEVLSGDTLPREKG--RMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQ---------------ISDIQVNGQSEDMSAKEKLLFWSQRMTEGYPGIRCDNFTTSWRDGKLFNAVIHKHYPRLIDMGKVYQQSNLENLEHAFNVAEKDLGVTRLLDPEDVDVPHPDEKSIITYVSSLYDV 254
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000016745.1 (SMESG000016745.1) HSP 1 Score: 12377.6 bits (32121), Expect = 0.000e+0 Identity = 6584/6646 (99.07%), Postives = 6595/6646 (99.23%), Query Frame = 1
Query: 136 MQIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIXXXXXXXXXXXXXQDLQAKLRLFNSITXXXXXXXXXXXXXXXXXXXXXXXXXKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGXXXXXXXXXXXXXQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSXXXXXXXXXXXXXXSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDXXXXXXXXXXXXXXEIETEKQMIFXXXXXXXXXXSEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNXXXXXXXXXXXXXXKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDXXXXXXXXXXXXXXDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRXXXXXXXXXXXDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFXXXXXXXXXXXXTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDXXXXXXXXXXXXXXXXVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQXXXXXXXXXXXXINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMXXXXXXXXXXXXVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNXXXXXXXXXXXXXRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETXXXXXXXXXXKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQXXXXXXXXXXXXXSISQLRDXXXXXXXXXXXXXXXXXXXDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLKNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYXXXXXXXXXXXXKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESAXXXXXXXXXXXXXXXXXXXXXXXYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIKIF*MTFLVSMNI*VRLMRLAKNR*W*LSLK*AMN*LS*KVRPVKYLIIYPNPLKI----KKHTIQSREILKAIAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTXXXXXXXXXXXXXNYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRXXXXXXXXXXXXXXXXXXXEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEKK 20061
MQIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIKLKEEAENEAEKLQDLQAKLRLFNSITIGEELILLGELRQQERVVEQIQELRKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGENFTEIENEIEIFQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSLQELNEEYQELLIQSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDSNISQLSQSINSQLEIETEKQMIFNNLKNKLINISEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNQISQIQQTISSEITKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDNRLKEIENLLENLEDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRSTESTITIEEIDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFSESSELSEDNSSTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDESKSIEIENINNLLNKVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQDLSDLVKKLDDSINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMEENRISEEIINSVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNSLSSADDCDSLLLRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETELLSSEAEASKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQLELKKNDLNLLENSISQLRDKESFASELLLLKSKLAAYEDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLKNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYVLLPLAPELVEEKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESALNSKLELLLNLKNLIDQQQNNIKYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIK + + S + + + ++L N L+ V K I+ N K K + I IAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTEEIIELDIKEKLENYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRDVDLMSDMSLHSSLSDTDHEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEK+
Sbjct: 1 MQIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIKLKEEAENEAEKLQDLQAKLRLFNSITIGEELILLGELRQQERVVEQIQELRKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGENFTEIENEIEIFQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSLQELNEEYQELLIQSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDSNISQLSQSINSQLEIETEKQMIFNNLKNKLINISEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNQISQIQQTISSEITKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDNRLKEIENLLENLEDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRSTESTITIEEIDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFSESSELSEDNSSTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDESKSIEIENINNLLNKVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQDLSDLVKKLDDSINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMEENRISEEIINSVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNSLSSADDCDSLLLRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETELLSSEAEASKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQLELKKNDLNLLENSISQLRDKESFASELLLLKSKLAAYEDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLKNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYVLLPLAPELVEEKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESALNSKLELLLNLKNLIDQQQNNIKYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIKDL-LNDISSFHEYLSSFDASGKESLMVALTEVSNELT--VLEGKTGEIFNNISKSLENQKTYNSIKGNIEGKIAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTEEIIELDIKEKLENYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRDVDLMSDMSLHSSLSDTDHEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEKE 6643 HSP 2 Score: 2159.41 bits (5594), Expect = 0.000e+0 Identity = 1104/1118 (98.75%), Postives = 1110/1118 (99.28%), Query Frame = 3
Query: 20022 KDEEIEQVYHGKENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILXXXXXXXXXXXXXXXXXYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHXXXXXXXXXXXXDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELKTNEEL 23375
K ++ + KENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILSDFEKDKDKDSFMKDQKYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHEGTNEGTENENNDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELK+ +E+
Sbjct: 6631 KTRKLNRCIMEKENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILSDFEKDKDKDSFMKDQKYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHEGTNEGTENENNDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELKSLDEI 7748 HSP 3 Score: 136.346 bits (342), Expect = 1.107e-30 Identity = 68/68 (100.00%), Postives = 68/68 (100.00%), Query Frame = 3
Query: 17412 DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG 17615
DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG
Sbjct: 5760 DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG 5827
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000016745.1 (SMESG000016745.1) HSP 1 Score: 12353.3 bits (32058), Expect = 0.000e+0 Identity = 6573/6645 (98.92%), Postives = 6589/6645 (99.16%), Query Frame = 1
Query: 139 QIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIXXXXXXXXXXXXXQDLQAKLRLFNSITXXXXXXXXXXXXXXXXXXXXXXXXXKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGXXXXXXXXXXXXXQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSXXXXXXXXXXXXXXSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDXXXXXXXXXXXXXXEIETEKQMIFXXXXXXXXXXSEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNXXXXXXXXXXXXXXKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDXXXXXXXXXXXXXXDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRXXXXXXXXXXXDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFXXXXXXXXXXXXTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDXXXXXXXXXXXXXXXXVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQXXXXXXXXXXXXINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMXXXXXXXXXXXXVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNXXXXXXXXXXXXXRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETXXXXXXXXXXKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQXXXXXXXXXXXXXSISQLRDXXXXXXXXXXXXXXXXXXXDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLKNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYXXXXXXXXXXXXKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESAXXXXXXXXXXXXXXXXXXXXXXXYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIKIF*MTFLVSMNI*VRLMRLAKNR*W*LSLK*AMN*LS*KVRPVKYLIIYPNPLKI----KKHTIQSREILKAIAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTXXXXXXXXXXXXXNYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRXXXXXXXXXXXXXXXXXXXEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEKK 20061
++ + K ++EQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIKLKEEAENEAEKLQDLQAKLRLFNSITIGEELILLGELRQQERVVEQIQELRKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGENFTEIENEIEIFQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSLQELNEEYQELLIQSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDSNISQLSQSINSQLEIETEKQMIFNNLKNKLINISEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNQISQIQQTISSEITKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDNRLKEIENLLENLEDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRSTESTITIEEIDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFSESSELSEDNSSTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDESKSIEIENINNLLNKVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQDLSDLVKKLDDSINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMEENRISEEIINSVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNSLSSADDCDSLLLRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETELLSSEAEASKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQLELKKNDLNLLENSISQLRDKESFASELLLLKSKLAAYEDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLKNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYVLLPLAPELVEEKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESALNSKLELLLNLKNLIDQQQNNIKYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIK + + S + + + ++L N L+ V K I+ N K K + I IAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTEEIIELDIKEKLENYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRDVDLMSDMSLHSSLSDTDHEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEK+
Sbjct: 43 RLSKTMAKRRNEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIKLKEEAENEAEKLQDLQAKLRLFNSITIGEELILLGELRQQERVVEQIQELRKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGENFTEIENEIEIFQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSLQELNEEYQELLIQSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDSNISQLSQSINSQLEIETEKQMIFNNLKNKLINISEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNQISQIQQTISSEITKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDNRLKEIENLLENLEDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRSTESTITIEEIDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFSESSELSEDNSSTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDESKSIEIENINNLLNKVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQDLSDLVKKLDDSINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMEENRISEEIINSVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNSLSSADDCDSLLLRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETELLSSEAEASKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQLELKKNDLNLLENSISQLRDKESFASELLLLKSKLAAYEDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLKNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYVLLPLAPELVEEKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESALNSKLELLLNLKNLIDQQQNNIKYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIKDL-LNDISSFHEYLSSFDASGKESLMVALTEVSNELT--VLEGKTGEIFNNISKSLENQKTYNSIKGNIEGKIAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTEEIIELDIKEKLENYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRDVDLMSDMSLHSSLSDTDHEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEKE 6684 HSP 2 Score: 2159.41 bits (5594), Expect = 0.000e+0 Identity = 1104/1118 (98.75%), Postives = 1110/1118 (99.28%), Query Frame = 3
Query: 20022 KDEEIEQVYHGKENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILXXXXXXXXXXXXXXXXXYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHXXXXXXXXXXXXDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELKTNEEL 23375
K ++ + KENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILSDFEKDKDKDSFMKDQKYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHEGTNEGTENENNDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELK+ +E+
Sbjct: 6672 KTRKLNRCIMEKENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILSDFEKDKDKDSFMKDQKYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHEGTNEGTENENNDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELKSLDEI 7789 HSP 3 Score: 136.346 bits (342), Expect = 1.135e-30 Identity = 68/68 (100.00%), Postives = 68/68 (100.00%), Query Frame = 3
Query: 17412 DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG 17615
DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG
Sbjct: 5801 DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG 5868
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000016745.1 (SMESG000016745.1) HSP 1 Score: 10007.5 bits (25968), Expect = 0.000e+0 Identity = 5324/5334 (99.81%), Postives = 5329/5334 (99.91%), Query Frame = 1
Query: 139 QIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIXXXXXXXXXXXXXQDLQAKLRLFNSITXXXXXXXXXXXXXXXXXXXXXXXXXKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGXXXXXXXXXXXXXQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSXXXXXXXXXXXXXXSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDXXXXXXXXXXXXXXEIETEKQMIFXXXXXXXXXXSEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNXXXXXXXXXXXXXXKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDXXXXXXXXXXXXXXDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRXXXXXXXXXXXDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFXXXXXXXXXXXXTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDXXXXXXXXXXXXXXXXVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQXXXXXXXXXXXXINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMXXXXXXXXXXXXVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNXXXXXXXXXXXXXRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETXXXXXXXXXXKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQXXXXXXXXXXXXXSISQLRDXXXXXXXXXXXXXXXXXXXDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLK 16140
++ + K ++EQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIKLKEEAENEAEKLQDLQAKLRLFNSITIGEELILLGELRQQERVVEQIQELRKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGENFTEIENEIEIFQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSLQELNEEYQELLIQSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDSNISQLSQSINSQLEIETEKQMIFNNLKNKLINISEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNQISQIQQTISSEITKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDNRLKEIENLLENLEDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRSTESTITIEEIDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFSESSELSEDNSSTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDESKSIEIENINNLLNKVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQDLSDLVKKLDDSINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMEENRISEEIINSVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNSLSSADDCDSLLLRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETELLSSEAEASKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQLELKKNDLNLLENSISQLRDKESFASELLLLKSKLAAYEDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLK
Sbjct: 43 RLSKTMAKRRNEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIKLKEEAENEAEKLQDLQAKLRLFNSITIGEELILLGELRQQERVVEQIQELRKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGENFTEIENEIEIFQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSLQELNEEYQELLIQSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDSNISQLSQSINSQLEIETEKQMIFNNLKNKLINISEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNQISQIQQTISSEITKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDNRLKEIENLLENLEDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRSTESTITIEEIDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFSESSELSEDNSSTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDESKSIEIENINNLLNKVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQDLSDLVKKLDDSINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMEENRISEEIINSVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNSLSSADDCDSLLLRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETELLSSEAEASKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQLELKKNDLNLLENSISQLRDKESFASELLLLKSKLAAYEDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLK 5376
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000016745.1 (SMESG000016745.1) HSP 1 Score: 9981.28 bits (25900), Expect = 0.000e+0 Identity = 5324/5334 (99.81%), Postives = 5329/5334 (99.91%), Query Frame = 1
Query: 139 QIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIXXXXXXXXXXXXXQDLQAKLRLFNSITXXXXXXXXXXXXXXXXXXXXXXXXXKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGXXXXXXXXXXXXXQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSXXXXXXXXXXXXXXSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDXXXXXXXXXXXXXXEIETEKQMIFXXXXXXXXXXSEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNXXXXXXXXXXXXXXKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDXXXXXXXXXXXXXXDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRXXXXXXXXXXXDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFXXXXXXXXXXXXTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDXXXXXXXXXXXXXXXXVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQXXXXXXXXXXXXINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMXXXXXXXXXXXXVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNXXXXXXXXXXXXXRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETXXXXXXXXXXKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQXXXXXXXXXXXXXSISQLRDXXXXXXXXXXXXXXXXXXXDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLK 16140
++ + K ++EQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIKLKEEAENEAEKLQDLQAKLRLFNSITIGEELILLGELRQQERVVEQIQELRKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGENFTEIENEIEIFQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSLQELNEEYQELLIQSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDSNISQLSQSINSQLEIETEKQMIFNNLKNKLINISEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNQISQIQQTISSEITKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDNRLKEIENLLENLEDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRSTESTITIEEIDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFSESSELSEDNSSTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDESKSIEIENINNLLNKVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQDLSDLVKKLDDSINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMEENRISEEIINSVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNSLSSADDCDSLLLRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETELLSSEAEASKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQLELKKNDLNLLENSISQLRDKESFASELLLLKSKLAAYEDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLK
Sbjct: 43 RLSKTMAKRRNEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYLSERKIKLVNINPSDIVEGKPVIVLGLIWLIILFFQIQEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTITRPESPRKKLKLSMPEPAKSNERGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQDFKAAKRLVLSCQWLLDESVNNGWKNLCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQIKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGNFVAIVTEMINDIEKLLSADPTFKEWAQEFKYHISDIEREIKYIETSLRTYIEEWHKMEELYNETVDWMNSTDDFSISPQEYISRKHKIAEMEKNIAFLSEQSSDSGKETLSRKLEYINLNFSRFHENKSLHVDNLRKEYKIKVENIKKWLEKSEALESLDINFSTDSVNEYVQILVESNKTSENVKEDFKDLSKIGQVISRTCSKEETERMLGELKIQKIRLLTLIEDRPKLIKKLSSLCEILNKCDSLLSNVDQAVGEIERELAEMLTNFQSKANQQQEMFLGEINVALESIKSKEQLLTNLKVYIAEIESLKVSNFPLKPIYARENETIEKLNNLRSFALLVSKKIQESSWLTPFKSRLETWIEETTSNLAILKNLETDSVNSLLENSLAMKDSMRIALDEILLKIQESDDDELKDEGNNLQSEFNKISSQLSEAESYRKFRILENKCIEFIKNIETQLDEEEMLVKHANLDKIQEIIYKHNVYFEECDFKVTSLSYLSEMKTLLENFPKNQAILSKAEMLERQCEDLSKRIDTVGSDLSNSENSLREKKEKISKLNELVINFTNVSSNLDLSDLNVTSDQYDMVLNKFCSLIPDVDNMKEVALELRNDGILSQEDIFEETISNFESIAPSVESLKRRGSNISDAIKLKEEAENEAEKLQDLQAKLRLFNSITIGEELILLGELRQQERVVEQIQELRKEIIENTGMKFTELELKDPTVALMVLPTIENLQLLCELAESQSVELLSHNSHIVNTKLSIKKEMDTLEAKIMNLQEAIVPSTFENEQIHPTILEAQMSIDFINESQSQFESQLSKDYTDFLSNFCKEKSEELEQIQQDAARKSNRKNVEKILRNCISHIELDLTNFDKFIYKIPLEKAKTILIEEKRICENAIKSNVDRLDHDLGEIVISHGDLNGEVRGIDLSEDASKVLVKVQTFSEQSNSLQKRLLDIQTVEDVRAWKDAWCELGNNIHSLCQSIDNIQSLLNYSNPSLKAELSLEKIDEIFTKIELLESNFDKQNVKIQSQLSRINEFESSIEGSIVSDMNQLLEYKEALSKYSEVINEIKQEEIIPFELKEFVTNLNENPGIELVVNQISKIRHNIESKVGMILDQENEKNSQIVNEVSLQLYDEFTETDNQLDARETISVLESSRIRLETLKTNTEALKSLSEKFGHYLSYEKTNKQINKTLKDCMEILDLCGAKIDVMEHCRSFVDQLNELEERVNRISEPLNDKEEIILDKITEINALKQNIMLLGESLVNLRERFSTNQIVICSAIEERYENLKSQSQSIETILDKKIKLLNEDKKRLDLLLNQRIEVSNNVEELIKSLDQIQWNSSDQMSIEHNYTVIQQLSDQFNDQITIINYCKQNLPGENFTEIENEIEIFQLKLANNNKKYEEQIDLISNVVEKSKCASLCFTLHSDPNSEVDVSNLIKNTMENTHDKLKSIELLKRKVDEQFESDDGELLQLLDRKQSQLANDLELIRSVSENHNSLIDLSGEVNSISNKIDKSIGTLKSILKSPEKSIIDVEGILEHTNCNLEKIMKIQTRQPILETPVSKEILSKIQEKLSKDINEVIHVTQSSLDPIHSLMSQYQRLKTDGDKCSDEVHYLEQMVTDNMGMPMIQEQLEHIDHITTTLCSIYDQVETNKQVFGIREICELSDHCISNKDKLNQIKYKILKQQEQIMKDQEQLETLTNQFNNIKADTLKKLSDFGSELHLKETVLSLDSLENTLCFGKEKIDLLKGIAMNIKNFNSEISMDCAKQVEEMEILLVDLDKSFMEIGEVIKVGNNRVNEIKEKYENLLARLDLESENVDFDFDEITGAIENCHVLKTELIETINGNYFKFEEVNDLLNRTVPINNDIDSLISRLELKLNVEQENQNQFINTKDILIAKSEDIRSIIERINQLVTELSKDLQSSNLEIKNVVNVLDIIQKDVERLLYIQSNELNLSSPVLNNEIVNLQTSISHEIAECTQSTQSFYNSIDNALGKYRRLKQQCDQYSDEIDFLQHEFLAEMDLEVLSKRLDEVNNLVQNENHLKDEIEVCKKVLNILETVGLHDECEGQIKALNGLHQNIEAQIKIINTDKQRLVELITYFTEIRNCAEESLTDFMVKVNNKKELLSLEKMSTITMKAIDSLDILNETKEKIKEYDLPESINKEIDIKNLSESLSEFKVNFNNITKIVEDGNKSLQELNEEYQELLIQSDVEKAEKNKNDFLEILKSKKDRIENLDKRLGFIINKIYPNFEEVNEVIRKTKLLDSNISQLSQSINSQLEIETEKQMIFNNLKNKLINISEEVKLIYQKILKTLNLIHKSSHSSMEEIELLIDNIEQDVAQLISIQLHKLNITSPVFFDNQISQIQQTISSEITKYVDDTKTSINHIRESIRQFLSCREDLTKLSDESHFLQLESLSDSNMASFDNRLKEIENLLENLEDICDRVDNLKPNFNCSEIEDLYNKITDLKLKLQELSTKTKDLQETNRINEEKLKNLLLIFQENAEKISAQLQMILDKSIDESACLNLKDTENCLCEFNNAADTLNGIIDNIGQLNNSSADKCRLRLDSLKLLNADLTNLYNNVDNIVKEKSTELNKIDSEYEALIKIDDFGMLKNLELKRDQLKELKDQMSMFNRIDQLNFKEIRHLELKTTNIIDKIDSSIEYLNGKIETEQSKEELLSQIDSELDENLKMITILFSRLRSTESTITIEEIDEMLHNISENMKIVIEEINDEILNQCPVPDEISKKINEINDKRVQLSGISLEIKENLKNNIQTLNFYKPLIDCHNSTLIKFSESSELSEDNSSTIEDISRQLIQSKDSLLALSESPSEYICKDKADFDESKSIEIENINNLLNKVQMLSDKFQFEKSKKEFLDELGKVKCENDSLKELIESGDPNLSNEEILNRIDRNIFAISDLEINYQDNPIVAEYLQRMIDYKHIAEGIKNQFNHYLSVLGNHGTFIDNIDQVLRQVKEQLNTDDLQSADDPTARMEKLTDLKNQLKYPELPIENKSKESEILLVKLQNINENIQQLSKEISKKEQHEKIKGKLNEIHRILKVFIENNIENPLKDINNYFSQSNSLMESVLRDVSEIDPETDRAQELISEINSQKCLISQVEESIGDLYGQMKTGAAIYGEHCQKIKDWTARKPIENFNDIINFKSLFKEHLKNLICWKKNLEPKIRCQDLSDLVKKLDDSINETITILENLECEEKKMRIESEMLTVLEAINTDITQLEQGGKGENKASFSKREIDENLSAIKNNLSIIQTQIDENEANMIDEKLKSSFLCTSNRVVQLDKTFEEKLQILSQLDIEKESIIQNLPTYEGVIDDTNEIRDLLTHLDNVTDIISKLTDIGIRYQEEGLQCIERTDSMSNVHAELANINHAKLLLEAKIKSKLEREAAFSDIKVFLGEIEKRLDNFKISLQMDNQDVPLANIEQTLGDIEKDFLNLQTPELLDETEFEEVIRDIGQNINTNKEYLLTLSQEITDKENVQKDLENQFNNCTNLKQFIPIDLVTQYKNHQSNFNQYERWRLLNCELCKEVKDLETEIHCREVHNLKEDIDRLGNNIKTIMTSEEGKIKETIEKLQENLERAKIEQETWLKEMIKTLQNSTQSSNLVPTIIQSKKEALESLIGSLETGHGLIDKIFELEEQMKEINSEFSDNQCTHRDRKASVIQYMELIQESQRRFADIADKYSQALEIANSLESFLKNIQIQLTNIPKENINAEKINQIISDLQSYRNSVESKLPMKDKLLLLEKALISESVSTNDLNTIDIENLYVKTVEDVDDFIGMISEIVKIYDELNVRLMEENRISEEIINSVTVLLDKEVTREQSLLSERPETLKALRQKLLDQHVTVKELRNEIENVHSEKSLISEMIPTVRKMESDLETNLKFVTERIDEIKSKMEIMDQVNVQAQELSNNLDGIEKDIQCLRSDNNLSQELMFWESKIENLQDISLNLSECEGKLNRLIEEVKGNEVEINPTDLKGRIRENERTINNLLQNWQHIQAISMEKENILNLINFLDNRIKFAEICENEIDLLQNALRDLLKLNEDIHSLDNKIHTINCIKMTGLSVDEQSYINFIVGDLERKLLDSSTKKKLIGDNLDEKLKQLTLLNDIHMDVLKITGGIFTNSLSSADDCDSLLLRFDEMKLRLEDLKHPEVIRDKKPMIDHLTQVFHETHNIIEEIKNRITLFECIQNDIESSALQIQNTQQLLLDPHSIAVDQIEDDLANIENQLETIQRNLQRNSLNLDFFHNDLLHFMSNNLQENLSSQIQRLDDIKFELNEHVKSLESQPEERFEPTFIENLNRESNFSFLIENDETELLSSEAEASKNPSNDLGLDENSINTTSSSHLTHKEELNELSGWISTEMDSLNNIEKSLTFHNPSISLIKPLIEQLELKKNDLNLLENSISQLRDKESFASELLLLKSKLAAYEDYLLNTLESTTDLDNHLSNFRLLADSLFDWMRRSREMLEGELTPLQQKSTVDKLKIESDEIQMTKIKKLKSLLCEIDKFEIIQDNANIQTSVKALFEEVLGKYDDLNTQIMDLYNDSPMKELENLIDVCEEFVYAIFPKWYKDQLRNTIVSGKECIIRITENRMKLAFIEENAEKLNKLIERCKVPWYKIQLDRDVNIPPHDINATNNILQIRHAKVVAKMFEIFKSLEKWMIILEDLKIKWQELNANQDQFQYWLIEIEKERDLREGKPLHLNDNSLKEKINFLKNLKIEIDKNSSELVKMMMIDDEVTTATFSPQLNNGENLRSTNTLSDRINNQYTLLTNKVLNQIEKWHNIFDKVEVFHKSADDLKEDFVHLKERVQKLETQGPLTKDKLNSLK 5376 HSP 2 Score: 2371.27 bits (6144), Expect = 0.000e+0 Identity = 1250/1312 (95.27%), Postives = 1261/1312 (96.11%), Query Frame = 1
Query: 16138 KNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYXXXXXXXXXXXXKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESAXXXXXXXXXXXXXXXXXXXXXXXYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIKIF*MTFLVSMNI*VRLMRLAKNR*W*LSLK*AMN*LS*KVRPVKYLIIYPNPLKI----KKHTIQSREILKAIAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTXXXXXXXXXXXXXNYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRXXXXXXXXXXXXXXXXXXXEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEKK 20061
KNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYVLLPLAPELVEEKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESALNSKLELLLNLKNLIDQQQNNIKYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIK + + S + + + ++L N L+ V K I+ N K K + I IAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTEEIIELDIKEKLENYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRDVDLMSDMSLHSSLSDTDHEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEK+
Sbjct: 5525 KNVELALNRIWAKFEYYRQAAHSLFLHLSEADKLILIEDIRQWEQNINDLKESLYTKNSFLIHSMNNYADLLYQIDENLSALEHLRNKLKNYVLLPLAPELVEEKQIEFQQLTSDIVDQEQRNEIIKISLECCVENLTKPEILRLQSDLDRLLNIFSAVKSDVENTRVYIDQVYNLRKNIHEILHKIEINRIENSRLSACFQHPTNDESALNSKLELLLNLKNLIDQQQNNIKYLDEYWHDISISTINEDRDMLENNIRDWNTSNQDLLTRTRREVQTTEKMIKYYQSCSNDFKIVKAYVNELDDHFQQNHPFNINSYYFLKKKQNRLGETFTALNRIFETLVENERSIPVECYQSMFDDAIQLKSRLINLEEKLGSEIEINEQSSLPVEIINWNGKLTDLIDRFNYFNQPFLCENNEIILVDIKDL-LNDISSFHEYLSSFDASGKESLMVALTEVSNELT--VLEGKTGEIFNNISKSLENQKTYNSIKGNIEGKIAEIKNHLDITEIPGVSLAARNYRYESDGQSLGNINENFDQLCSLSQKLTENGDDNYKEKIVGELLMIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTPEKVGLEVKDVDQRIQFYQLMKTQFLDLIEQSSEWVESLNDDYKSTEEIIELDIKEKLENYSEFKEIFQEYHPKKVAALYGARETRIRMSRFRKAISDWIESATILRNRTEVQSATIDRNQGILKNLDIVDNLMNLDLGNLEGERSQLNMIFGDGTFCPCDEAYESYISLCENLIPYVAENDSLSLKSDLTNLSSSIGELKIFNSKSLEKIGFLQDLLETFKTDCEHLDTQMDSIEICVMNISKNLNAVDSEGELTHQNFAALTMTVDYIRDNLTPRLDRMFGSCQKMYTICNPASLQVIIDDYQHRKIRLKDTESNCCQLTAFIDNQLKSKTTEDLLNNRVKVELTSASGAIWSDEFIEKESSKHILNNIEDIKSHQRILTDLEETITLSCNGADCLHNLNSSQTGHQQLMFEQIEKVKNSLNLCLLKCEDEVDFRNQINLFKQQISPQLSELNQSFDYPIDIKQLAEIADNFRNVFLKVCRFQDEVRQHYQYGSDRNSAILFDVIQSCQSVKSKIKSVLEVTDMNNVDSDVLLNITELIGEFDEDEKTTTQIRDVDLMSDMSLHSSLSDTDHEAIVTDWLVSARRILKETYFEDVNDLVLKIEESNQLLEWDVNKNIEKILQSSESSDRSTEVIGEYRNTREHLHRSLNDFMLKSMKYNECVLAAHKCFQWLDISDIQMADADEKTRKLNRCIMEKE 6833 HSP 3 Score: 2157.87 bits (5590), Expect = 0.000e+0 Identity = 1104/1118 (98.75%), Postives = 1110/1118 (99.28%), Query Frame = 3
Query: 20022 KDEEIEQVYHGKENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILXXXXXXXXXXXXXXXXXYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHXXXXXXXXXXXXDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELKTNEEL 23375
K ++ + KENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILSDFEKDKDKDSFMKDQKYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHEGTNEGTENENNDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELK+ +E+
Sbjct: 6821 KTRKLNRCIMEKENIEQLLLDLQDGDHFRAKPAIIVNVLSNLSAEIERLCEESLTNTKTFDCEESSFPNAIKKPTTSLDINDDTYEEYLQKNYDNQGDSGSKDFSDIPFKKLKTNELSLSESMLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSSIGDYSSTETESICIDSNESGNDDANENRIITNLKSSSNVNDLYFTPFQANDDFSTDIKQENEDAANQKALNSNNNAVESKNENPAIELEIYENVPGIEGNEKKSVFDTLSVDVNPAELLNAGGHLQSGNAYNQEFEISHRDNLSKESKCLETNLNKEPTDSINEKSGFQNNFSKISDNNYANEEFTDEMLTERDNLFYSEDEDDFISTEERIECEIIPLTKTSVGFNFEIETTADGIINKEVYNEEDLAARFKDLDIYRKEIGNENFDRSNKKELNDNQEIDSLLIDKSVDLDIESIKQDSVELIENDSPLVVELAHPLEMMLERKISLPDIKTHFDNLENSDGNIEKDIQINFKVENNDSKENMEFIEKDQKSLDENLLMENDNSSERKPDGSEDGIQDKDSELSNTDNLVEIGKSPVEIPKLLIKKVDVIMKDQKSVITMEDSPEMSLILSPERNSLEKDEIDPSKLKDADILVTGLGLDMVSVMSDSDYYTATTGTGDPLNTYNMLLSCSSNVDESEKVDSYSKLKPPVEIDETIVKDFDYVISKAPEDQNDDLDINKNETLILSDFEKDKDKDSFMKDQKYLTAKGDLSEIPLVSTSERNALPMDELKPFDPSKEIINLQEIESRFHEGTNEGTENENNDMATVISDPINVNYKSVNSECGDPDYNTATAAVDPLNTGNTSYFCSSNAGDSGSFSDISKTALKEDNVTFMAEDEVEKQYEIKYSETTLLLEPERKTLGSIEENPVDQLNENGNIFLEGIDTFTERDLNIKGSAAQTDNTEYAVDCESAETENRMVESPDNTRKPDLENKEKDNIVNSNYINDSFHLTMESSIHDKDPLMQNIEGEMSSLAPKLSDSAFSRCHRSSSGGDLDYVSNPEFDIHEGSQNVGDTKLNLSESTGDDSYRSRSPLFEIESEIIPTEVGIQRIQRDNKSKELKSLDEI 7938 HSP 4 Score: 136.346 bits (342), Expect = 1.136e-30 Identity = 68/68 (100.00%), Postives = 68/68 (100.00%), Query Frame = 3
Query: 17412 DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG 17615
DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG
Sbjct: 5950 DLLNDISSFHEYLSSFDASGKESLMVALTEVSNELTVLEGKTGEIFNNISKSLENQKTYNSIKGNIEG 6017
BLAST of Nesprin-1 vs. Planmine SMEST
Match: SMESG000077685.1 (SMESG000077685.1) HSP 1 Score: 215.312 bits (547), Expect = 1.677e-54 Identity = 190/552 (34.42%), Postives = 302/552 (54.71%), Query Frame = 1
Query: 166 KDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLMLIYLLEVLSGSTMRKERGPNMKKLHYLSNVKIALNYL-SERKIKLVNINPSDIVEGKPXXXXXXXXXXXXXXXXXEHELDKKSQQSGAVRQANANNSASDKGVKLKLLTWIQNIIPREYNMTITDFGKSWSSGIAFHALIEVFNPNLVDMKIVLQGDPQKNLDSAFDIAERHLGIAKLLDSEDVIAEKPDEKSIMTYVSQFLELTI--TRPESPRKKLK-------LSMPEPAKSNE----RGVNDKIKRFIINVKESRIEKLKQIENFNDVFKLISNLKNELELIPEWDQTSSTGDLLLDQ--------DFKAAKRLVLSCQWLLDESVNNGWKN-LCKWLISSERILEFHKNNQIDVSKEISPELLDDLTVQ-IKEYETHFKNSPFHSPTLAELKRCMINTDKNNKVFISYTISVERRIQKVVKEEFSIRQKLLLLHKIASLKMKEKEINYKLQYWKREFDSLANAEDRLLDFESAMANGN----FVAIVTEMINDIEKLLSADPTFKE 1737
KDEQ+ +QKKTFTKW+N YL + +I+KDL D+ DGL+L+ LLE+L+ +T++KE+ NM+K+H LSN++ AL ++ +++KIKLVNINPSD+V+GKP IVLGL+W IL FQI+E E A+ AN N+ K L+ W N + +Y + I DFG+SW G AF+AL+ +P LV+M+ + +G ++ L++AF+IAE LGI KLLDSEDV EKPDEKSIMTYV+QFL+ +PE+ +++ +SM +P NE + NDK+ + E L N+ D+F + + +++++L+ D+ S+ L LD DF + + QW LD+ + + + WL +E L ++ + + +D +Q +KE+E+ F + LA+ + + N N + +++ R++ V K E +R+KL + A+LK K ++ L W S + D++ F +M NG F + + E++ K +P E
Sbjct: 15 KDEQEKMQKKTFTKWMNSYLCQKKPPIIIKDLMKDLSDGLLLLDLLEILTKTTLKKEKPKNMQKIHCLSNIRTALEFMENDKKIKLVNINPSDVVDGKPAIVLGLVWTAILHFQIEEQE----EFLLQALGMANDPNAKVKGQAKKGLMAWTNNALSDKYGLNIKDFGESWCDGRAFNALVHNIDPTLVNMEEIEKGTNKERLENAFNIAENELGIPKLLDSEDVDVEKPDEKSIMTYVAQFLKSYPEGKKPENISEEITAEINSGLMSMVQPP--NELDIVKDFNDKVDK--------NFENLNSKNNY-DIFADLMSQRDDMKLL--LDKMSTDNYLDLDANDVRQVIGDFDKTEMKLNEWQWDLDKVLPGILGSEIGSWLQDAEESL-------MEPFPNVHDKTFNDKVLQKLKEHESIFNKK---NDVLAKFREVLQNPPAN--ISPKQLEAMKTRMENVCKAEGPVREKLNIFGIQANLKNKAQKWAVDLNSWDSPIQSKQDLLDKIEQFNISMENGTSMDKFTSQLDELVKRKVKFCKENPVLDE 537 The following BLAST results are available for this feature:
BLAST of Nesprin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Nesprin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Nesprin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Nesprin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Nesprin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Nesprin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015584 ID=SMED30015584|Name=Nesprin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=23779bpback to top protein sequence of SMED30015584-orf-1 >SMED30015584-orf-1 ID=SMED30015584-orf-1|Name=SMED30015584-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=772bp MIRSSINELTQHIATASLQTKSSIKERKNLLEMIMKALEKLKLMSDSVSTback to top protein sequence of SMED30015584-orf-2 >SMED30015584-orf-2 ID=SMED30015584-orf-2|Name=SMED30015584-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1101bp MLTEDTSIKFNQDSSTGVNFADSKYNSNEYGSENNGQLSNGIDDNESRLSback to top protein sequence of SMED30015584-orf-3 >SMED30015584-orf-3 ID=SMED30015584-orf-3|Name=SMED30015584-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=5762bp MQIGNIIRKYKDEQDFIQKKTFTKWINKYLKKHDSNLIVKDLFVDIRDGLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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