F-box and WD-40 domain-containing protein 1/11
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015580 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Human
Match: FBXW11 (F-box and WD repeat domain containing 11 [Source:HGNC Symbol;Acc:HGNC:13607]) HSP 1 Score: 59.6918 bits (143), Expect = 3.864e-13 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L FS+ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 309 AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 504 HSP 2 Score: 36.1946 bits (82), Expect = 3.864e-13 Identity = 22/84 (26.19%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I ++E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 223 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHH 306 HSP 3 Score: 51.9878 bits (123), Expect = 3.809e-6 Identity = 60/256 (23.44%), Postives = 113/256 (44.14%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W + + +K+L GH GS+ L+ + S D T+R+ + G L+ L+ ++ +R + L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 226 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KTSLECLKVLTGHTGSVLCLQYDERVIVT--GSSDSTVRVWDVNTGEVLNTLI------HHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 460
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Human
Match: FBXW11 (F-box and WD repeat domain containing 11 [Source:HGNC Symbol;Acc:HGNC:13607]) HSP 1 Score: 59.3066 bits (142), Expect = 5.023e-13 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L FS+ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 288 AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 483 HSP 2 Score: 35.8094 bits (81), Expect = 5.023e-13 Identity = 22/84 (26.19%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I ++E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 202 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHH 285 HSP 3 Score: 51.9878 bits (123), Expect = 4.337e-6 Identity = 60/256 (23.44%), Postives = 113/256 (44.14%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W + + +K+L GH GS+ L+ + S D T+R+ + G L+ L+ ++ +R + L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 205 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KTSLECLKVLTGHTGSVLCLQYDERVIVT--GSSDSTVRVWDVNTGEVLNTLI------HHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 439
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Human
Match: FBXW11 (F-box and WD repeat domain containing 11 [Source:HGNC Symbol;Acc:HGNC:13607]) HSP 1 Score: 59.3066 bits (142), Expect = 5.950e-13 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L FS+ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 322 AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 517 HSP 2 Score: 35.8094 bits (81), Expect = 5.950e-13 Identity = 22/84 (26.19%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I ++E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 236 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHH 319 HSP 3 Score: 51.6026 bits (122), Expect = 5.134e-6 Identity = 60/256 (23.44%), Postives = 113/256 (44.14%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W + + +K+L GH GS+ L+ + S D T+R+ + G L+ L+ ++ +R + L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 239 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KTSLECLKVLTGHTGSVLCLQYDERVIVT--GSSDSTVRVWDVNTGEVLNTLI------HHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 473
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Human
Match: BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:1144]) HSP 1 Score: 53.1434 bits (126), Expect = 2.383e-11 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 349 AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 496 HSP 2 Score: 36.5798 bits (83), Expect = 2.383e-11 Identity = 23/84 (27.38%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 263 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH 346
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Human
Match: BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:1144]) HSP 1 Score: 52.7582 bits (125), Expect = 3.137e-11 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 385 AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 532 HSP 2 Score: 36.5798 bits (83), Expect = 3.137e-11 Identity = 23/84 (27.38%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 299 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH 382
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Celegans
Match: lin-23 (F-box/WD repeat-containing protein lin-23 [Source:UniProtKB/Swiss-Prot;Acc:Q09990]) HSP 1 Score: 55.8398 bits (133), Expect = 1.226e-12 Identity = 42/171 (24.56%), Postives = 85/171 (49.71%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEI 2121
AV L F++ I+V+ D SI VW + ++ ++ ++L GH ++ + AS D T+++ SM D L ++++ GI ++ L+ +G D TIRL D+ C+ + +++++C+ F ++SG + G ++ W+ ++ A +EI
Sbjct: 304 AVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVS--ASGDRTIKVWSM-----DTLEFVRTLAGHRRGIACLQYRG--RLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEI 465 HSP 2 Score: 36.965 bits (84), Expect = 1.226e-12 Identity = 15/44 (34.09%), Postives = 25/44 (56.82%), Query Frame = 2
Query: 1436 LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
L+GH V +++D + S S D ++R+WD +G I+ L H
Sbjct: 258 LSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHH 301 HSP 3 Score: 50.447 bits (119), Expect = 5.602e-6 Identity = 60/255 (23.53%), Postives = 113/255 (44.31%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDM--DRLDCIYNI--GYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + +VSG D +I +W +++S +IL GH GS+ L+ S D T+R+ + ++ IK++ ++ +R ++ T D++I + DM R I + G++ + + F ++S ++ W+ + F V T I L Y R + + +D +I+ W + S C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 221 NSKGVYCLQYDDDKIVSGLRDNTIKIWD-RKDYSCSRILSGHTGSVLCLQYDNRVIIS--GSSDATVRV-----WDVETGECIKTLIHHCEAVLHLRF--ANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRA-AVNVVDFDDRYIVSASGDRTIKVWSMDTLEF---------VRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAA 455
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Celegans
Match: lin-23 (F-box/WD repeat-containing protein lin-23 [Source:UniProtKB/Swiss-Prot;Acc:Q09990]) HSP 1 Score: 55.8398 bits (133), Expect = 1.226e-12 Identity = 42/171 (24.56%), Postives = 85/171 (49.71%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEI 2121
AV L F++ I+V+ D SI VW + ++ ++ ++L GH ++ + AS D T+++ SM D L ++++ GI ++ L+ +G D TIRL D+ C+ + +++++C+ F ++SG + G ++ W+ ++ A +EI
Sbjct: 304 AVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVS--ASGDRTIKVWSM-----DTLEFVRTLAGHRRGIACLQYRG--RLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEI 465 HSP 2 Score: 36.965 bits (84), Expect = 1.226e-12 Identity = 15/44 (34.09%), Postives = 25/44 (56.82%), Query Frame = 2
Query: 1436 LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
L+GH V +++D + S S D ++R+WD +G I+ L H
Sbjct: 258 LSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHH 301 HSP 3 Score: 50.447 bits (119), Expect = 5.602e-6 Identity = 60/255 (23.53%), Postives = 113/255 (44.31%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDM--DRLDCIYNI--GYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + +VSG D +I +W +++S +IL GH GS+ L+ S D T+R+ + ++ IK++ ++ +R ++ T D++I + DM R I + G++ + + F ++S ++ W+ + F V T I L Y R + + +D +I+ W + S C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 221 NSKGVYCLQYDDDKIVSGLRDNTIKIWD-RKDYSCSRILSGHTGSVLCLQYDNRVIIS--GSSDATVRV-----WDVETGECIKTLIHHCEAVLHLRF--ANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRA-AVNVVDFDDRYIVSASGDRTIKVWSMDTLEF---------VRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAA 455
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Celegans
Match: lin-23 (F-box/WD repeat-containing protein lin-23 [Source:UniProtKB/Swiss-Prot;Acc:Q09990]) HSP 1 Score: 55.8398 bits (133), Expect = 1.301e-12 Identity = 42/171 (24.56%), Postives = 85/171 (49.71%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEI 2121
AV L F++ I+V+ D SI VW + ++ ++ ++L GH ++ + AS D T+++ SM D L ++++ GI ++ L+ +G D TIRL D+ C+ + +++++C+ F ++SG + G ++ W+ ++ A +EI
Sbjct: 249 AVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVS--ASGDRTIKVWSM-----DTLEFVRTLAGHRRGIACLQYRG--RLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEI 410 HSP 2 Score: 36.965 bits (84), Expect = 1.301e-12 Identity = 15/44 (34.09%), Postives = 25/44 (56.82%), Query Frame = 2
Query: 1436 LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
L+GH V +++D + S S D ++R+WD +G I+ L H
Sbjct: 203 LSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHH 246 HSP 3 Score: 49.6766 bits (117), Expect = 7.739e-6 Identity = 60/255 (23.53%), Postives = 113/255 (44.31%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDM--DRLDCIYNI--GYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + +VSG D +I +W +++S +IL GH GS+ L+ S D T+R+ + ++ IK++ ++ +R ++ T D++I + DM R I + G++ + + F ++S ++ W+ + F V T I L Y R + + +D +I+ W + S C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 166 NSKGVYCLQYDDDKIVSGLRDNTIKIWD-RKDYSCSRILSGHTGSVLCLQYDNRVIIS--GSSDATVRV-----WDVETGECIKTLIHHCEAVLHLRF--ANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRA-AVNVVDFDDRYIVSASGDRTIKVWSMDTLEF---------VRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAA 400
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Celegans
Match: lin-23 (F-box/WD repeat-containing protein lin-23 [Source:UniProtKB/Swiss-Prot;Acc:Q09990]) HSP 1 Score: 55.8398 bits (133), Expect = 1.334e-12 Identity = 42/171 (24.56%), Postives = 85/171 (49.71%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEI 2121
AV L F++ I+V+ D SI VW + ++ ++ ++L GH ++ + AS D T+++ SM D L ++++ GI ++ L+ +G D TIRL D+ C+ + +++++C+ F ++SG + G ++ W+ ++ A +EI
Sbjct: 249 AVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVS--ASGDRTIKVWSM-----DTLEFVRTLAGHRRGIACLQYRG--RLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEI 410 HSP 2 Score: 36.965 bits (84), Expect = 1.334e-12 Identity = 15/44 (34.09%), Postives = 25/44 (56.82%), Query Frame = 2
Query: 1436 LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
L+GH V +++D + S S D ++R+WD +G I+ L H
Sbjct: 203 LSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHH 246 HSP 3 Score: 49.6766 bits (117), Expect = 7.862e-6 Identity = 60/255 (23.53%), Postives = 113/255 (44.31%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDM--DRLDCIYNI--GYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + +VSG D +I +W +++S +IL GH GS+ L+ S D T+R+ + ++ IK++ ++ +R ++ T D++I + DM R I + G++ + + F ++S ++ W+ + F V T I L Y R + + +D +I+ W + S C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 166 NSKGVYCLQYDDDKIVSGLRDNTIKIWD-RKDYSCSRILSGHTGSVLCLQYDNRVIIS--GSSDATVRV-----WDVETGECIKTLIHHCEAVLHLRF--ANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRA-AVNVVDFDDRYIVSASGDRTIKVWSMDTLEF---------VRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAA 400
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Celegans
Match: lin-23 (F-box/WD repeat-containing protein lin-23 [Source:UniProtKB/Swiss-Prot;Acc:Q09990]) HSP 1 Score: 55.8398 bits (133), Expect = 1.341e-12 Identity = 42/171 (24.56%), Postives = 85/171 (49.71%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEI 2121
AV L F++ I+V+ D SI VW + ++ ++ ++L GH ++ + AS D T+++ SM D L ++++ GI ++ L+ +G D TIRL D+ C+ + +++++C+ F ++SG + G ++ W+ ++ A +EI
Sbjct: 304 AVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVS--ASGDRTIKVWSM-----DTLEFVRTLAGHRRGIACLQYRG--RLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEI 465 HSP 2 Score: 36.965 bits (84), Expect = 1.341e-12 Identity = 15/44 (34.09%), Postives = 25/44 (56.82%), Query Frame = 2
Query: 1436 LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
L+GH V +++D + S S D ++R+WD +G I+ L H
Sbjct: 258 LSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHH 301 HSP 3 Score: 50.0618 bits (118), Expect = 6.254e-6 Identity = 60/255 (23.53%), Postives = 113/255 (44.31%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDM--DRLDCIYNI--GYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + +VSG D +I +W +++S +IL GH GS+ L+ S D T+R+ + ++ IK++ ++ +R ++ T D++I + DM R I + G++ + + F ++S ++ W+ + F V T I L Y R + + +D +I+ W + S C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 221 NSKGVYCLQYDDDKIVSGLRDNTIKIWD-RKDYSCSRILSGHTGSVLCLQYDNRVIIS--GSSDATVRV-----WDVETGECIKTLIHHCEAVLHLRF--ANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRA-AVNVVDFDDRYIVSASGDRTIKVWSMDTLEF---------VRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAA 455
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Fly
Match: slmb (gene:FBgn0283468 transcript:FBtr0084032) HSP 1 Score: 53.1434 bits (126), Expect = 8.661e-11 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + +L ++L GH ++ + + AS D T+++ S + ++++N GI ++ + L+ +G D +IRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 292 AVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVS--ASGDRTIKVWSTSSCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWD 439 HSP 2 Score: 33.8834 bits (76), Expect = 8.661e-11 Identity = 16/49 (32.65%), Postives = 25/49 (51.02%), Query Frame = 2
Query: 1424 NCYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K L GH V +++D + S S D ++R+WD +G + L H
Sbjct: 241 QCVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHH 289
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Fly
Match: slmb (gene:FBgn0283468 transcript:FBtr0333931) HSP 1 Score: 53.1434 bits (126), Expect = 8.661e-11 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + +L ++L GH ++ + + AS D T+++ S + ++++N GI ++ + L+ +G D +IRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 292 AVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVS--ASGDRTIKVWSTSSCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWD 439 HSP 2 Score: 33.8834 bits (76), Expect = 8.661e-11 Identity = 16/49 (32.65%), Postives = 25/49 (51.02%), Query Frame = 2
Query: 1424 NCYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K L GH V +++D + S S D ++R+WD +G + L H
Sbjct: 241 QCVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHH 289
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Fly
Match: slmb (gene:FBgn0283468 transcript:FBtr0330049) HSP 1 Score: 52.7582 bits (125), Expect = 1.118e-10 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + +L ++L GH ++ + + AS D T+++ S + ++++N GI ++ + L+ +G D +IRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 292 AVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVS--ASGDRTIKVWSTSSCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWD 439 HSP 2 Score: 33.8834 bits (76), Expect = 1.118e-10 Identity = 16/48 (33.33%), Postives = 25/48 (52.08%), Query Frame = 2
Query: 1427 CYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K L GH V +++D + S S D ++R+WD +G + L H
Sbjct: 242 CVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHH 289
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Fly
Match: Lis-1 (gene:FBgn0015754 transcript:FBtr0087241) HSP 1 Score: 48.521 bits (114), Expect = 1.920e-10 Identity = 48/238 (20.17%), Postives = 104/238 (43.70%), Query Frame = 1
Query: 1627 LDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCL----------------------YFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHM--RSLWTAHNDGSIKEWYLASMTCIRTLYGHK 2268
D ++L S D+SI +W +Q++ IK ++GH +++S+ + + ++SAS D T+++ +++ +K+ + +R+ ++ AT D+TIR+ + DC + + ++C+ + Q L SG ++ W+ + + + T + L +H + L +A +D +I+ W L + C++TLY H+
Sbjct: 158 FDAQGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKM-----WEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLC---------LLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQ 381 HSP 2 Score: 36.965 bits (84), Expect = 1.920e-10 Identity = 20/48 (41.67%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1430 YKLTGHLDGVTMVKFDK--SRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
+ LTGH +T V F + M S+S D ++RIWD +G R L GH
Sbjct: 102 FSLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGH 149
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Fly
Match: Lis-1 (gene:FBgn0015754 transcript:FBtr0304747) HSP 1 Score: 48.521 bits (114), Expect = 1.920e-10 Identity = 48/238 (20.17%), Postives = 104/238 (43.70%), Query Frame = 1
Query: 1627 LDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCL----------------------YFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHM--RSLWTAHNDGSIKEWYLASMTCIRTLYGHK 2268
D ++L S D+SI +W +Q++ IK ++GH +++S+ + + ++SAS D T+++ +++ +K+ + +R+ ++ AT D+TIR+ + DC + + ++C+ + Q L SG ++ W+ + + + T + L +H + L +A +D +I+ W L + C++TLY H+
Sbjct: 158 FDAQGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKM-----WEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLC---------LLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQ 381 HSP 2 Score: 36.965 bits (84), Expect = 1.920e-10 Identity = 20/48 (41.67%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1430 YKLTGHLDGVTMVKFDK--SRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
+ LTGH +T V F + M S+S D ++RIWD +G R L GH
Sbjct: 102 FSLTGHRASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGH 149
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Zebrafish
Match: fbxw11b (F-box and WD repeat domain containing 11b [Source:ZFIN;Acc:ZDB-GENE-040426-2903]) HSP 1 Score: 58.9214 bits (141), Expect = 1.567e-13 Identity = 62/261 (23.75%), Postives = 112/261 (42.91%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWR-LKKSHSRETHDEKP 2388
AV L F + ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW L S + +T P
Sbjct: 304 AVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSTNGQTEGRSP 515 HSP 2 Score: 37.7354 bits (86), Expect = 1.567e-13 Identity = 24/84 (28.57%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I T+E LTGH V +++D+ + + S D ++R+WD SG + L H
Sbjct: 218 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHH 301 HSP 3 Score: 53.5286 bits (127), Expect = 7.333e-7 Identity = 62/256 (24.22%), Postives = 114/256 (44.53%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W +Q +KIL GH G + L L + +++ S D T+R+ + G L+ L+ ++ +R L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 221 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KQTLECLKILTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLI------HHNEAVLHLRF--CNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 455
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Zebrafish
Match: fbxw11b (F-box and WD repeat domain containing 11b [Source:ZFIN;Acc:ZDB-GENE-040426-2903]) HSP 1 Score: 58.9214 bits (141), Expect = 1.714e-13 Identity = 62/261 (23.75%), Postives = 112/261 (42.91%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWR-LKKSHSRETHDEKP 2388
AV L F + ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW L S + +T P
Sbjct: 311 AVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSTNGQTEGRSP 522 HSP 2 Score: 37.7354 bits (86), Expect = 1.714e-13 Identity = 24/84 (28.57%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I T+E LTGH V +++D+ + + S D ++R+WD SG + L H
Sbjct: 225 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHH 308 HSP 3 Score: 53.5286 bits (127), Expect = 7.856e-7 Identity = 62/256 (24.22%), Postives = 114/256 (44.53%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W +Q +KIL GH G + L L + +++ S D T+R+ + G L+ L+ ++ +R L+ T D++I + DM I +G+ + + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 228 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KQTLECLKILTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLI------HHNEAVLHLRF--CNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGH-RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 462
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Zebrafish
Match: fbxw11b (F-box and WD repeat domain containing 11b [Source:ZFIN;Acc:ZDB-GENE-040426-2903]) HSP 1 Score: 58.9214 bits (141), Expect = 1.743e-13 Identity = 62/261 (23.75%), Postives = 112/261 (42.91%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWR-LKKSHSRETHDEKP 2388
AV L F + ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW L S + +T P
Sbjct: 307 AVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSTNGQTEGRSP 518 HSP 2 Score: 37.7354 bits (86), Expect = 1.743e-13 Identity = 24/84 (28.57%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I T+E LTGH V +++D+ + + S D ++R+WD SG + L H
Sbjct: 221 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHH 304 HSP 3 Score: 53.5286 bits (127), Expect = 9.209e-7 Identity = 62/256 (24.22%), Postives = 114/256 (44.53%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W +Q +KIL GH G + L L + +++ S D T+R+ + G L+ L+ ++ +R L+ T D++I + DM I +G+ + + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 224 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KQTLECLKILTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLI------HHNEAVLHLRF--CNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGH-RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 458
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Zebrafish
Match: fbxw11b (F-box and WD repeat domain containing 11b [Source:ZFIN;Acc:ZDB-GENE-040426-2903]) HSP 1 Score: 58.9214 bits (141), Expect = 1.743e-13 Identity = 62/261 (23.75%), Postives = 112/261 (42.91%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWR-LKKSHSRETHDEKP 2388
AV L F + ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW L S + +T P
Sbjct: 307 AVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSTNGQTEGRSP 518 HSP 2 Score: 37.7354 bits (86), Expect = 1.743e-13 Identity = 24/84 (28.57%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I T+E LTGH V +++D+ + + S D ++R+WD SG + L H
Sbjct: 221 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHH 304 HSP 3 Score: 53.5286 bits (127), Expect = 9.209e-7 Identity = 62/256 (24.22%), Postives = 114/256 (44.53%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W +Q +KIL GH G + L L + +++ S D T+R+ + G L+ L+ ++ +R L+ T D++I + DM I +G+ + + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 224 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KQTLECLKILTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLI------HHNEAVLHLRF--CNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGH-RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 458
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Zebrafish
Match: fbxw11b (F-box and WD repeat domain containing 11b [Source:ZFIN;Acc:ZDB-GENE-040426-2903]) HSP 1 Score: 58.5362 bits (140), Expect = 1.815e-13 Identity = 62/261 (23.75%), Postives = 112/261 (42.91%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWR-LKKSHSRETHDEKP 2388
AV L F + ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW L S + +T P
Sbjct: 314 AVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVSTNGQTEGRSP 525 HSP 2 Score: 37.7354 bits (86), Expect = 1.815e-13 Identity = 24/84 (28.57%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I T+E LTGH V +++D+ + + S D ++R+WD SG + L H
Sbjct: 228 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHH 311 HSP 3 Score: 53.1434 bits (126), Expect = 1.048e-6 Identity = 62/256 (24.22%), Postives = 114/256 (44.53%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W +Q +KIL GH G + L L + +++ S D T+R+ + G L+ L+ ++ +R L+ T D++I + DM I +G+ + + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 231 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KQTLECLKILTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLI------HHNEAVLHLRF--CNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGH-RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 465
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Xenopus
Match: btrc (beta-transducin repeat containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:549140]) HSP 1 Score: 53.1434 bits (126), Expect = 1.243e-10 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 266 AVLHLRFNNGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 413 HSP 2 Score: 34.2686 bits (77), Expect = 1.243e-10 Identity = 22/84 (26.19%), Postives = 40/84 (47.62%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E L GH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 180 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH 263
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Xenopus
Match: btrc (beta-transducin repeat containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:549140]) HSP 1 Score: 53.1434 bits (126), Expect = 1.288e-10 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 347 AVLHLRFNNGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 494 HSP 2 Score: 34.2686 bits (77), Expect = 1.288e-10 Identity = 22/84 (26.19%), Postives = 40/84 (47.62%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E L GH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 261 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH 344
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Xenopus
Match: btrc (beta-transducin repeat containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:549140]) HSP 1 Score: 53.1434 bits (126), Expect = 1.309e-10 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 344 AVLHLRFNNGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 491 HSP 2 Score: 34.2686 bits (77), Expect = 1.309e-10 Identity = 22/84 (26.19%), Postives = 40/84 (47.62%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E L GH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 258 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH 341
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Xenopus
Match: btrc (beta-transducin repeat containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:549140]) HSP 1 Score: 52.7582 bits (125), Expect = 1.320e-10 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 350 AVLHLRFNNGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 497 HSP 2 Score: 34.2686 bits (77), Expect = 1.320e-10 Identity = 22/84 (26.19%), Postives = 40/84 (47.62%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E L GH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 264 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH 347
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Xenopus
Match: btrc (beta-transducin repeat containing E3 ubiquitin protein ligase [Source:NCBI gene;Acc:549140]) HSP 1 Score: 53.1434 bits (126), Expect = 1.353e-10 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 339 AVLHLRFNNGMMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 486 HSP 2 Score: 34.2686 bits (77), Expect = 1.353e-10 Identity = 22/84 (26.19%), Postives = 40/84 (47.62%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E L GH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 253 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH 336
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Mouse
Match: Fbxw11 (F-box and WD-40 domain protein 11 [Source:MGI Symbol;Acc:MGI:2144023]) HSP 1 Score: 59.6918 bits (143), Expect = 5.813e-13 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L FS+ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 309 AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 504 HSP 2 Score: 35.039 bits (79), Expect = 5.813e-13 Identity = 16/48 (33.33%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1427 CYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 259 CLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHH 306 HSP 3 Score: 51.2174 bits (121), Expect = 4.657e-6 Identity = 60/256 (23.44%), Postives = 112/256 (43.75%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + ++SG D SI +W + + +K+L GH GS+ L+ + S D T+R+ + G L+ L+ ++ +R + L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 226 NSKGVYCLQYDDDKIISGLRDNSIKIWD-KSSLECLKVLTGHTGSVLCLQYDERVIVT--GSSDSTVRVWDVNTGEVLNTLI------HHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 460
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Mouse
Match: Fbxw11 (F-box and WD-40 domain protein 11 [Source:MGI Symbol;Acc:MGI:2144023]) HSP 1 Score: 59.3066 bits (142), Expect = 6.452e-13 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L FS+ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 343 AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 538 HSP 2 Score: 35.039 bits (79), Expect = 6.452e-13 Identity = 16/48 (33.33%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1427 CYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 293 CLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHH 340 HSP 3 Score: 51.2174 bits (121), Expect = 5.347e-6 Identity = 60/256 (23.44%), Postives = 112/256 (43.75%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + ++SG D SI +W + + +K+L GH GS+ L+ + S D T+R+ + G L+ L+ ++ +R + L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 260 NSKGVYCLQYDDDKIISGLRDNSIKIWD-KSSLECLKVLTGHTGSVLCLQYDERVIVT--GSSDSTVRVWDVNTGEVLNTLI------HHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 494
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Mouse
Match: Fbxw11 (F-box and WD-40 domain protein 11 [Source:MGI Symbol;Acc:MGI:2144023]) HSP 1 Score: 59.3066 bits (142), Expect = 8.734e-13 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L FS+ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 322 AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 517 HSP 2 Score: 35.039 bits (79), Expect = 8.734e-13 Identity = 16/48 (33.33%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1427 CYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 272 CLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHH 319 HSP 3 Score: 50.8322 bits (120), Expect = 6.061e-6 Identity = 60/256 (23.44%), Postives = 112/256 (43.75%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + ++SG D SI +W + + +K+L GH GS+ L+ + S D T+R+ + G L+ L+ ++ +R + L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 239 NSKGVYCLQYDDDKIISGLRDNSIKIWD-KSSLECLKVLTGHTGSVLCLQYDERVIVT--GSSDSTVRVWDVNTGEVLNTLI------HHNEAVLHLRF--SNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 473
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Mouse
Match: Btrc (beta-transducin repeat containing protein [Source:MGI Symbol;Acc:MGI:1338871]) HSP 1 Score: 53.9138 bits (128), Expect = 7.621e-12 Identity = 57/261 (21.84%), Postives = 110/261 (42.15%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRETHDEKPQ 2391
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++ D + P A C+RTL H G + L F + + SSS D +I IW + H E P+
Sbjct: 349 AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLMAALDPRAP---------------------------AGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPA--AHAEPPR 558 HSP 2 Score: 36.965 bits (84), Expect = 7.621e-12 Identity = 23/84 (27.38%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 263 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKSTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHH 346
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Mouse
Match: Btrc (beta-transducin repeat containing protein [Source:MGI Symbol;Acc:MGI:1338871]) HSP 1 Score: 53.5286 bits (127), Expect = 1.059e-11 Identity = 57/261 (21.84%), Postives = 110/261 (42.15%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRETHDEKPQ 2391
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++ D + P A C+RTL H G + L F + + SSS D +I IW + H E P+
Sbjct: 286 AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLMAALDPRAP---------------------------AGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPA--AHAEPPR 495 HSP 2 Score: 36.5798 bits (83), Expect = 1.059e-11 Identity = 23/84 (27.38%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 200 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKSTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHH 283
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. UniProt/SwissProt
Match: sp|Q9UKB1|FBW1B_HUMAN (F-box/WD repeat-containing protein 11 OS=Homo sapiens OX=9606 GN=FBXW11 PE=1 SV=1) HSP 1 Score: 59.3066 bits (142), Expect = 2.638e-12 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L FS+ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 322 AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 517 HSP 2 Score: 35.8094 bits (81), Expect = 2.638e-12 Identity = 22/84 (26.19%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I ++E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 236 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHH 319
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. UniProt/SwissProt
Match: sp|Q5SRY7|FBW1B_MOUSE (F-box/WD repeat-containing protein 11 OS=Mus musculus OX=10090 GN=Fbxw11 PE=1 SV=1) HSP 1 Score: 59.3066 bits (142), Expect = 5.321e-12 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L FS+ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 322 AVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 517 HSP 2 Score: 35.039 bits (79), Expect = 5.321e-12 Identity = 16/48 (33.33%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1427 CYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 272 CLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHH 319
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. UniProt/SwissProt
Match: sp|Q09990|LIN23_CAEEL (F-box/WD repeat-containing protein lin-23 OS=Caenorhabditis elegans OX=6239 GN=lin-23 PE=1 SV=2) HSP 1 Score: 55.8398 bits (133), Expect = 1.407e-11 Identity = 42/171 (24.56%), Postives = 85/171 (49.71%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEI 2121
AV L F++ I+V+ D SI VW + ++ ++ ++L GH ++ + AS D T+++ SM D L ++++ GI ++ L+ +G D TIRL D+ C+ + +++++C+ F ++SG + G ++ W+ ++ A +EI
Sbjct: 304 AVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVS--ASGDRTIKVWSM-----DTLEFVRTLAGHRRGIACLQYRG--RLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEI 465 HSP 2 Score: 36.965 bits (84), Expect = 1.407e-11 Identity = 15/44 (34.09%), Postives = 25/44 (56.82%), Query Frame = 2
Query: 1436 LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
L+GH V +++D + S S D ++R+WD +G I+ L H
Sbjct: 258 LSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHH 301
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. UniProt/SwissProt
Match: sp|Q3ULA2|FBW1A_MOUSE (F-box/WD repeat-containing protein 1A OS=Mus musculus OX=10090 GN=Btrc PE=1 SV=2) HSP 1 Score: 53.5286 bits (127), Expect = 6.631e-11 Identity = 57/261 (21.84%), Postives = 110/261 (42.15%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRETHDEKPQ 2391
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++ D + P A C+RTL H G + L F + + SSS D +I IW + H E P+
Sbjct: 385 AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLMAALDPRAP---------------------------AGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPA--AHAEPPR 594 HSP 2 Score: 36.965 bits (84), Expect = 6.631e-11 Identity = 23/84 (27.38%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 299 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKSTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHH 382
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. UniProt/SwissProt
Match: sp|Q9Y297|FBW1A_HUMAN (F-box/WD repeat-containing protein 1A OS=Homo sapiens OX=9606 GN=BTRC PE=1 SV=1) HSP 1 Score: 52.7582 bits (125), Expect = 1.391e-10 Identity = 36/157 (22.93%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW + + +L ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 385 AVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 532 HSP 2 Score: 36.5798 bits (83), Expect = 1.391e-10 Identity = 23/84 (27.38%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + + S T++I T+E LTGH V +++D+ + + S D ++R+WD +G + L H
Sbjct: 299 RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHH 382
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. TrEMBL
Match: A0A267GEN7 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002741g3 PE=4 SV=1) HSP 1 Score: 124.79 bits (312), Expect = 6.551e-50 Identity = 74/249 (29.72%), Postives = 123/249 (49.40%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLK 2352
++G V CL +L +G WDMS+ +WSLE +F +++L H S+ + +L L++A+ D T R++ ++ L P+ + + + L AT D+ +RL D+ + G +D + CL+ LL++G G L FW+ A A+ + L++ L SLW H+DG+I+EW++ASMTC+R+L GHK ++ L + S S D RIW +
Sbjct: 760 HKGGVTCLHMRDNVLATGSWDMSVMLWSLEPDFRRLRMLTDHEDSVCYVHILPGSRNLVTAAFDATARVYEPPTYRQVALARF------PSPVTQAAVAGEQQL-ATAHADRQLRLTDLATGRLLRQFGAHRDAVTCLHASGDLLVTGTRRGRLHFWDARTGQCEAAVQAD-----PGRAALTV--LRLRRGSLWAGHSDGTIREWHVASMTCVRSLAGHKAAVRDLQATAKRVASVSEDAFARIWEFR 994 HSP 2 Score: 104.76 bits (260), Expect = 6.551e-50 Identity = 59/125 (47.20%), Postives = 78/125 (62.40%), Query Frame = 2
Query: 1199 DTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWL-DSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHK 1570
D R LMKPI+G+LKQFQ+SE++A+D + LV D ++SESK L + D + A G+ +L I C L GHLD V ++FD+ R+ + S D S+RIWD SGRSIRKLYGHK
Sbjct: 644 DRRPLMKPILGRLKQFQDSEDVALDIRP-RLVEATDLTEKSESKERLIYKKDLEKLGQRGAFVGD------ILPILQCRLLQGHLDAVQCLQFDERRLVTGSRDMSVRIWDVRSGRSIRKLYGHK 761
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. TrEMBL
Match: A0A267DQU3 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002741g2 PE=4 SV=1) HSP 1 Score: 124.79 bits (312), Expect = 6.661e-50 Identity = 74/249 (29.72%), Postives = 123/249 (49.40%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLK 2352
++G V CL +L +G WDMS+ +WSLE +F +++L H S+ + +L L++A+ D T R++ ++ L P+ + + + L AT D+ +RL D+ + G +D + CL+ LL++G G L FW+ A A+ + L++ L SLW H+DG+I+EW++ASMTC+R+L GHK ++ L + S S D RIW +
Sbjct: 758 HKGGVTCLHMRDNVLATGSWDMSVMLWSLEPDFRRLRMLTDHEDSVCYVHILPGSRNLVTAAFDATARVYEPPTYRQVALARF------PSPVTQAAVAGEQQL-ATAHADRQLRLTDLATGRLLRQFGAHRDAVTCLHASGDLLVTGTRRGRLHFWDARTGQCEAAVQAD-----PGRAALTV--LRLRRGSLWAGHSDGTIREWHVASMTCVRSLAGHKAAVRDLQATAKRVASVSEDAFARIWEFR 992 HSP 2 Score: 104.76 bits (260), Expect = 6.661e-50 Identity = 59/125 (47.20%), Postives = 78/125 (62.40%), Query Frame = 2
Query: 1199 DTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWL-DSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHK 1570
D R LMKPI+G+LKQFQ+SE++A+D + LV D ++SESK L + D + A G+ +L I C L GHLD V ++FD+ R+ + S D S+RIWD SGRSIRKLYGHK
Sbjct: 642 DRRPLMKPILGRLKQFQDSEDVALDIRP-RLVEATDLTEKSESKERLIYKKDLEKLGQRGAFVGD------ILPILQCRLLQGHLDAVQCLQFDERRLVTGSRDMSVRIWDVRSGRSIRKLYGHK 759
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. TrEMBL
Match: A0A267GQQ0 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002741g1 PE=4 SV=1) HSP 1 Score: 124.79 bits (312), Expect = 6.942e-50 Identity = 74/249 (29.72%), Postives = 123/249 (49.40%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLK 2352
++G V CL +L +G WDMS+ +WSLE +F +++L H S+ + +L L++A+ D T R++ ++ L P+ + + + L AT D+ +RL D+ + G +D + CL+ LL++G G L FW+ A A+ + L++ L SLW H+DG+I+EW++ASMTC+R+L GHK ++ L + S S D RIW +
Sbjct: 761 HKGGVTCLHMRDNVLATGSWDMSVMLWSLEPDFRRLRMLTDHEDSVCFVHILPGSRNLVTAAFDATARVYEPPTYRQLALARF------PSPVTQAAVAGEQQL-ATAHADRQLRLTDLATGRLLRQFGAHRDAVTCLHASGDLLVTGTRRGRLHFWDARTGQCEAAVQAD-----PGRAALTV--LRLRRGSLWAGHSDGTIREWHVASMTCVRSLAGHKAAVRDLQATAKRVASVSEDAFARIWEFR 995 HSP 2 Score: 104.76 bits (260), Expect = 6.942e-50 Identity = 59/125 (47.20%), Postives = 78/125 (62.40%), Query Frame = 2
Query: 1199 DTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWL-DSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHK 1570
D R LMKPI+G+LKQFQ+SE++A+D + LV D ++SESK L + D + A G+ +L I C L GHLD V ++FD+ R+ + S D S+RIWD SGRSIRKLYGHK
Sbjct: 645 DRRPLMKPILGRLKQFQDSEDVALDIRP-RLVEATDLTEKSESKERLIYKKDLEKLGQRGAFVGD------ILPILQCRLLQGHLDAVQCLQFDERRLVTGSRDMSVRIWDVRSGRSIRKLYGHK 762
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. TrEMBL
Match: A0A1I8H7A0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 122.479 bits (306), Expect = 3.794e-32 Identity = 88/315 (27.94%), Postives = 148/315 (46.98%), Query Frame = 2
Query: 635 TKIDKYKILIEILCAENWDIQFHVYQCVKSRLLDRWSMDSIPTKILENIFYYFSPDELIKASLVNKQWLSVALNNGLWENHCATLGKSLGFTKFVEMMEENIADSARINWFEIYKAIRKLSRQNNSVIDVKNNIRKSKITFYEAAXXXXXXXXXXXFLXXXXXXXXXXXXXXKTSIKFNNVLDPDPEN--DTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWL-DSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHK 1570
+ ++ +L E++ + + ++ C+ R+ D + +P + L IF +L+ + V++ W +A + +W C +G G ++ + + I+W Y + ++ RQ + + ++ + EA + RR + + +VLD D R LMKPI+G+LKQFQ+SE++A+D + LV D ++SESK L + D + A G+ +L I C L GHLD V ++FD+ R+ + S D S+RIWD SGRSIRKLYGHK
Sbjct: 239 PEFERINLLSELVTVCSQQLIAYLADCIMQRIHDCTDIGILPDRTLLKIFSMLPVRDLLSCAQVSRHWWVLASHESIWLRRCEQIGFENGLLNLAGVLRQRLG-LQHIDWKLTYGELERMLRQARQSLPLPRHLTHNAAVDGEA---------------------KAKRREQQQQLDGVSVLDRIHREYADRRPLMKPILGRLKQFQDSEDVALDIRP-RLVEATDLTEKSESKERLIYKKDLEKLGQRGAFVGD------ILPILQCRLLQGHLDAVQCLQFDERRLVTGSRDMSVRIWDVRSGRSIRKLYGHK 524 HSP 2 Score: 47.3654 bits (111), Expect = 3.794e-32 Identity = 17/42 (40.48%), Postives = 27/42 (64.29%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGH 1731
++G V CL +L +G WDMS+ +WSLE +F +++L H
Sbjct: 523 HKGGVTCLHMRDNVLATGSWDMSVMLWSLEPDFRRLRMLTDH 564
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. TrEMBL
Match: A0A1I8GRM3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 120.553 bits (301), Expect = 1.760e-31 Identity = 84/313 (26.84%), Postives = 144/313 (46.01%), Query Frame = 2
Query: 635 TKIDKYKILIEILCAENWDIQFHVYQCVKSRLLDRWSMDSIPTKILENIFYYFSPDELIKASLVNKQWLSVALNNGLWENHCATLGKSLGFTKFVEMMEENIADSARINWFEIYKAIRKLSRQNNSVIDVKNNIRKSKITFYEAAXXXXXXXXXXXFLXXXXXXXXXXXXXXKTSIKFNNVLDPDPENDTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWL-DSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHK 1570
+ ++ +L E++ + + ++ C+ R+ D + +P + L IF +L+ + V++ W +A + +W C +G G ++ + + I+W Y + ++ RQ + + ++ + EA + + + +S D R LMKPI+G+LKQFQ+SE++A+D + LV D ++SESK L + D + A G+ +L I C L GHLD V ++FD+ R+ + S D S+RIWD SGRSIRKLYGHK
Sbjct: 301 PEFERINLLSELVTVCSQQLIAYLADCIMQRIHDCTDIGILPDRTLLKIFSLLPVRDLLSCAQVSRHWWVLASHESIWLRRCEQIGFENGLLNLAGVLRQRLG-LQHIDWKLTYGELERMLRQARQSLPLPRHLTHNAAVDGEAKAKRREQQQQLDGVSVLERIHREYA-------------------DRRPLMKPILGRLKQFQDSEDVALDIRP-RLVEATDLTEKSESKERLIYKKDLEKLGQRGAFVGD------ILPILQCRLLQGHLDAVQCLQFDERRLVTGSRDMSVRIWDVRSGRSIRKLYGHK 586 HSP 2 Score: 46.9802 bits (110), Expect = 1.760e-31 Identity = 17/42 (40.48%), Postives = 27/42 (64.29%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGH 1731
++G V CL +L +G WDMS+ +WSLE +F +++L H
Sbjct: 585 HKGGVTCLHMRDNVLATGSWDMSVMLWSLEPDFRRLRMLTDH 626
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Cavefish
Match: fbxw11a (F-box/WD repeat-containing protein 11 [Source:NCBI gene;Acc:103028966]) HSP 1 Score: 58.9214 bits (141), Expect = 2.554e-13 Identity = 58/245 (23.67%), Postives = 106/245 (43.27%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L F + ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 305 AVLHLRFCNGLMVTCSKDRSIAVWDMASATDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 500 HSP 2 Score: 36.965 bits (84), Expect = 2.554e-13 Identity = 17/48 (35.42%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1427 CYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K LTGH V +++D + + S D ++R+WD+ SG + L H
Sbjct: 255 CLKILTGHTGSVLCLQYDDRVIVTGSSDSTVRVWDASSGEVLNTLIHH 302 HSP 3 Score: 51.2174 bits (121), Expect = 3.609e-6 Identity = 61/256 (23.83%), Postives = 110/256 (42.97%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRI-HSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + ++SG D SI +W + + +KIL GH GS+ L+ S D T+R+ + G L+ L+ ++ +R L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 222 NSKGVYCLQYDDDKIISGLRDNSIKIWD-KHSLECLKILTGHTGSVLCLQYDDRVIVT--GSSDSTVRVWDASSGEVLNTLI------HHNEAVLHLRF--CNGLMVTCSKDRSIAVWDMASATDISLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 456
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Cavefish
Match: fbxw11a (F-box/WD repeat-containing protein 11 [Source:NCBI gene;Acc:103028966]) HSP 1 Score: 58.5362 bits (140), Expect = 2.699e-13 Identity = 58/245 (23.67%), Postives = 106/245 (43.27%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L F + ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 340 AVLHLRFCNGLMVTCSKDRSIAVWDMASATDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 535 HSP 2 Score: 36.965 bits (84), Expect = 2.699e-13 Identity = 17/48 (35.42%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1427 CYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K LTGH V +++D + + S D ++R+WD+ SG + L H
Sbjct: 290 CLKILTGHTGSVLCLQYDDRVIVTGSSDSTVRVWDASSGEVLNTLIHH 337 HSP 3 Score: 51.2174 bits (121), Expect = 4.259e-6 Identity = 61/256 (23.83%), Postives = 110/256 (42.97%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRI-HSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + ++SG D SI +W + + +KIL GH GS+ L+ S D T+R+ + G L+ L+ ++ +R L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 257 NSKGVYCLQYDDDKIISGLRDNSIKIWD-KHSLECLKILTGHTGSVLCLQYDDRVIVT--GSSDSTVRVWDASSGEVLNTLI------HHNEAVLHLRF--CNGLMVTCSKDRSIAVWDMASATDISLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 491
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Cavefish
Match: fbxw11b (F-box/WD repeat-containing protein 11-like [Source:NCBI gene;Acc:103029337]) HSP 1 Score: 58.5362 bits (140), Expect = 5.915e-13 Identity = 58/245 (23.67%), Postives = 106/245 (43.27%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L F + ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 313 AVLHLRFCNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 508 HSP 2 Score: 35.8094 bits (81), Expect = 5.915e-13 Identity = 17/48 (35.42%), Postives = 27/48 (56.25%), Query Frame = 2
Query: 1427 CYK-LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
C K LTGH V +++D+ + + S D ++R+WD SG + L H
Sbjct: 263 CLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLIHH 310 HSP 3 Score: 52.7582 bits (125), Expect = 1.285e-6 Identity = 62/256 (24.22%), Postives = 114/256 (44.53%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + ++SG D SI +W +Q+ +KIL GH G + L L + +++ S D T+R+ + G L+ L+ ++ +R L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 230 NSKGVYCLQYDDDKIISGLRDNSIKIWD-KQSLECLKILTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNSGEVLNTLI------HHNEAVLHLRF--CNGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 464
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Cavefish
Match: fbxw7 (F-box and WD repeat domain containing 7 [Source:NCBI gene;Acc:103046885]) HSP 1 Score: 43.5134 bits (101), Expect = 4.127e-10 Identity = 39/166 (23.49%), Postives = 74/166 (44.58%), Query Frame = 1
Query: 1612 GAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNI-GYQK--DVIKCLYFQSHLLISGGHSGFLQFWNTNPSVF 2097
AV C+ + + +VSG +D + VW E + + L GH L ++S SLD ++R+ ++ G + L +S+ S +E N++ +G D T+++ D+ C+ + G K + CL F + +I+ G ++ W+ F
Sbjct: 585 AAVRCVQYDGRRVVSGAYDFMVKVWDPETE-TCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG--------MELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEF 739 HSP 2 Score: 41.2022 bits (95), Expect = 4.127e-10 Identity = 20/65 (30.77%), Postives = 33/65 (50.77%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
S + TL++ T + + L GH V + + R+ S S D +LR+WD +G+ + L GH
Sbjct: 519 SGSTDRTLKVWNAETGDCIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 583 HSP 3 Score: 59.3066 bits (142), Expect = 1.333e-8 Identity = 57/252 (22.62%), Postives = 114/252 (45.24%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRET 2373
+ CL F +VSG D ++ VWS L + L GH G + S ++ S D TL++ + + I ++ + + M + E R + +G D T+R+ D++ C++ + ++C+ + ++SG + ++ W+ E + +Q T++ L + + SL D SI+ W + + CI TL GH+ + + D+++ S + D +++IW +K +T
Sbjct: 467 ITCLQFCGNRIVSGSDDNTLKVWSAVTGKCL-RTLVGHTGGVWSSQMRDNIIIS--GSTDRTLKV-----WNAETGDCIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPET----ETCLHTLQGHTNRVYSLQFDGIHVVSGSL-----DTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQT 699 HSP 4 Score: 39.6614 bits (91), Expect = 1.824e-6 Identity = 19/70 (27.14%), Postives = 36/70 (51.43%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHKVKSY 1582
S + TL++ + T + + L GH+ V V++D R+ S + D +++WD + + L GH + Y
Sbjct: 559 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 628 HSP 5 Score: 32.3426 bits (72), Expect = 1.824e-6 Identity = 33/124 (26.61%), Postives = 58/124 (46.77%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNI 1989
VY L F +VSG D SI VW +E + I L GH + ++L +A D T++I +K + L T++ + + + ++ +N + T D T++L D+ + I N+
Sbjct: 627 VYSLQFDGIHVVSGSLDTSIRVWDVETG-NCIHTLTGHQSLTSGMELKDNILVSGNA--DSTVKIWDIKTGQC--LQTLQGPHKHQSAVTCLQF--NKNFVITSSDDGTVKLWDLRTGEFIRNL 743
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Cavefish
Match: fbxw7 (F-box and WD repeat domain containing 7 [Source:NCBI gene;Acc:103046885]) HSP 1 Score: 43.5134 bits (101), Expect = 5.371e-10 Identity = 37/166 (22.29%), Postives = 73/166 (43.98%), Query Frame = 1
Query: 1612 GAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIG---YQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVF 2097
AV C+ + + +VSG +D + VW E + + L GH L ++S SLD ++R+ ++ G + L +S+ S +E N++ +G D T+++ D+ C+ + + + CL F + +I+ G ++ W+ F
Sbjct: 343 AAVRCVQYDGRRVVSGAYDFMVKVWDPETE-TCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG--------MELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLRTGEF 497 HSP 2 Score: 40.817 bits (94), Expect = 5.371e-10 Identity = 20/65 (30.77%), Postives = 33/65 (50.77%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
S + TL++ T + + L GH V + + R+ S S D +LR+WD +G+ + L GH
Sbjct: 277 SGSTDRTLKVWNAETGDCIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 341 HSP 3 Score: 59.6918 bits (143), Expect = 9.950e-9 Identity = 57/252 (22.62%), Postives = 114/252 (45.24%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRET 2373
+ CL F +VSG D ++ VWS L + L GH G + S ++ S D TL++ + + I ++ + + M + E R + +G D T+R+ D++ C++ + ++C+ + ++SG + ++ W+ E + +Q T++ L + + SL D SI+ W + + CI TL GH+ + + D+++ S + D +++IW +K +T
Sbjct: 225 ITCLQFCGNRIVSGSDDNTLKVWSAVTGKCL-RTLVGHTGGVWSSQMRDNIIIS--GSTDRTLKV-----WNAETGDCIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPET----ETCLHTLQGHTNRVYSLQFDGIHVVSGSL-----DTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQT 457 HSP 4 Score: 39.6614 bits (91), Expect = 3.255e-6 Identity = 19/70 (27.14%), Postives = 36/70 (51.43%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHKVKSY 1582
S + TL++ + T + + L GH+ V V++D R+ S + D +++WD + + L GH + Y
Sbjct: 317 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 386 HSP 5 Score: 31.5722 bits (70), Expect = 3.255e-6 Identity = 33/124 (26.61%), Postives = 58/124 (46.77%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNI 1989
VY L F +VSG D SI VW +E + I L GH + ++L +A D T++I +K + L T++ + + + ++ +N + T D T++L D+ + I N+
Sbjct: 385 VYSLQFDGIHVVSGSLDTSIRVWDVETG-NCIHTLTGHQSLTSGMELKDNILVSGNA--DSTVKIWDIKTGQC--LQTLQGPHKHQSAVTCLQFN--KNFVITSSDDGTVKLWDLRTGEFIRNL 501
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Sea Lamprey
Match: BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:1144]) HSP 1 Score: 55.0694 bits (131), Expect = 7.008e-11 Identity = 38/157 (24.20%), Postives = 80/157 (50.96%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F++ ++V+ D SI VW L + SL ++L GH ++ + AS D T+++ + + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+
Sbjct: 351 AVLHLRFTNGLMVTCSKDRSIAVWDLASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWNTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 498 HSP 2 Score: 29.6462 bits (65), Expect = 7.008e-11 Identity = 28/128 (21.88%), Postives = 55/128 (42.97%), Query Frame = 2
Query: 1184 PDPENDTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
P + R L IIG ++ +++ NL + + RSES + L + E S T++++ + ++ GHL + + + +F+ S D ++R+WD +G + L H
Sbjct: 229 PQANSFYRALYPKIIGDIETIESNWRCG----RHNLQRI---QCRSESSKGVYCLQYDDEKIVSGLRDNTIKVKATIKVKATTH-HGHLIFFMFLLYVQLYVFTGSSDSTVRVWDVNTGEMVNTLIHH 348
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008862.1 (pep scaffold:Pmarinus_7.0:GL476579:86637:114999:1 gene:ENSPMAG00000008000.1 transcript:ENSPMAT00000008862.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 59.6918 bits (143), Expect = 1.881e-9 Identity = 56/252 (22.22%), Postives = 113/252 (44.84%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRET 2373
+ CL F +VSG D ++ VWS L + L GH G + S ++ S D TL++ + D + ++ + + M + R + +G D T+R+ D++ C++ + ++C+ + ++SG + ++ W+ E + +Q T++ L + + SL D SI+ W + TC+ TL GH+ + + D+++ S + D +++IW +K +T
Sbjct: 237 ITCLQFCGNRIVSGSDDNTLKVWSAVTGKCL-RTLVGHTGGVWSSQMRGNIIVS--GSTDRTLKV-----WNADTGQCVHTLYGHTSTVRCMHLHGNR--VVSGSRDATLRVWDIETGQCLHVLAGHVAAVRCVQYDGRRVVSGAYDYTVKVWDPE----SETCLHTLQGHTNRVYSLQFDGVHIVSGSL-----DTSIRVWDAETGTCLHTLVGHQSLTSGMELRDNILVSGNADSTVKIWDIKTGQCLQT 469
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Yeast
Match: MET30 (F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus; dissociation of Met30p from SCF complex in response to cadmium stress is regulated by Cdc48p [Source:SGD;Acc:S000001308]) HSP 1 Score: 46.2098 bits (108), Expect = 8.736e-10 Identity = 21/65 (32.31%), Postives = 37/65 (56.92%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
+ + T+ I + T + +L+GH DGV + FD ++ + SLD ++R+W+ I+G I GH
Sbjct: 317 TGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYFDDRKLITGSLDKTIRVWNYITGECISTYRGH 381 HSP 2 Score: 34.2686 bits (77), Expect = 8.736e-10 Identity = 55/235 (23.40%), Postives = 90/235 (38.30%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLID------MDRLDCIYNIGYQKDVI-KCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLW----------TAHNDGSIKEWYLASMTCIRTLYGHK 2268
+V +D +++VSG D ++ VW +E L GH + +KL S S D T+R+ ++ L + + II + I++ NL D + D D D N Q+ V+ + + + +HLL S G ++ W D K I + F H+ +W + +DGSIK W L S C+ T G +
Sbjct: 384 SVLSVDSYQKVIVSGSADKTVKVWHVESRTCYT--LRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSC--LKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTMTDGADESDTPSN--EQETVLDENIPYPTHLL-SCGLDNTIKLW-------------------DVKTGKCIRTQFGHVEGVWDIAADNFRIISGSHDGSIKVWDLQSGKCMHTFNGRR 592
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Yeast
Match: CAF4 (WD40 repeat-containing protein associated with the CCR4-NOT complex; interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission; CAF4 has a paralog, MDV1, that arose from the whole genome duplication [Source:SGD;Acc:S000001744]) HSP 1 Score: 49.6766 bits (117), Expect = 1.486e-6 Identity = 49/184 (26.63%), Postives = 75/184 (40.76%), Query Frame = 1
Query: 1912 NLIATGLCDKTIRLIDMD-----RLD--------------CIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN-TNPSVFHEASMAEIQVFTDKKLPLS---------------IESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N++ TG D T++L D++ LD CI+N KD I L F S L+SG + W+ T + + +D K+P I +L + +L T DG ++ W L +R L GH I L F + + + S+D S+RIW L+ S
Sbjct: 376 NMLITGSKDATLKLWDLNLSREIYLDHSPLKEKTEEIVTPCIHNFELHKDEITALSFDSEALVSGSRDKKIFHWDLTTGKCIQQLDLIFTPTHSDIKMPARSLNNGACLLGTEAPMIGALQCYNSALATGTKDGIVRLWDLRVGKPVRLLEGHTDGITSLKFDSEKLVTGSMDNSVRIWDLRTS 559
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Nematostella
Match: EDO44093 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWV7]) HSP 1 Score: 91.2781 bits (225), Expect = 3.214e-28 Identity = 67/248 (27.02%), Postives = 120/248 (48.39%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRL 2349
++G V CL F ++ ++SG WDM+I VW + + F+ + +LYGH G ++ L+ + S D T+R+ M+ ++ ++ ++ + + E + +G DKTI+L +++ DC+ + D + + L++SG G + FW+ + A A + SL Y ++A D IKEW + + TC+RTL GH+G + + + DGS+RIW L
Sbjct: 188 HKGGVRCLQFDNERIISGSWDMTIMVWHIVK-FTRLHVLYGHKGCVSCLRFDENTLVS--GSHDSTIRVWDMRTWEC--VLVLQGHEGAVSCL-----EFDAPFVLSGSADKTIKLWNVESGDCLNTLRGHADAVTSVKVIGELILSGSADGMILFWDLDSGHCEAAIQAH---------EGPVHSLSYANDHFFSAGGDNMIKEWDVGTCTCLRTLQGHRGPVQDVMVGHHYILVEHYDGSVRIWDL 416 HSP 2 Score: 53.1434 bits (126), Expect = 3.214e-28 Identity = 26/59 (44.07%), Postives = 39/59 (66.10%), Query Frame = 2
Query: 1394 LQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHK 1570
L +R L ++ L GH+D V ++FD+ R+ + S D ++R+WD SGRSIRK+ GHK
Sbjct: 132 LDVRPAL-VQAANVLKGHMDVVLCLQFDRRRVVTGSSDRTIRMWDVRSGRSIRKMKGHK 189 HSP 3 Score: 55.4546 bits (132), Expect = 4.746e-8 Identity = 39/148 (26.35%), Postives = 71/148 (47.97%), Query Frame = 1
Query: 1909 RNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLK 2352
R + TG D+TIR+ D+ I + K ++CL F + +ISG W+ V+H + V K +S L + +L + +D +I+ W + + C+ L GH+G+++ L F + S S D +I++W ++
Sbjct: 159 RRRVVTGSSDRTIRMWDVRSGRSIRKMKGHKGGVRCLQFDNERIISGS-------WDMTIMVWHIVKFTRLHVLYGHKGCVS--CLRFDENTLVSGSHDSTIRVWDMRTWECVLVLQGHEGAVSCLEFDAPFVLSGSADKTIKLWNVE 297
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Nematostella
Match: EDO48720 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIJ5]) HSP 1 Score: 58.9214 bits (141), Expect = 1.051e-13 Identity = 60/256 (23.44%), Postives = 109/256 (42.58%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRETH 2376
AV L F ++V+ D SI VW ++ + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W ++Q D + P A C+RTL H G + L F D + SSS D +I IW K + T+
Sbjct: 246 AVLHLRFQEGMMVTCSKDRSIAVWDMQSPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHRRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVW-------------DLQAALDPRAP---------------------------AGTLCLRTLVEHTGRVFRLQFDDFQIVSSSHDDTILIWDFLKDATERTY 452 HSP 2 Score: 36.1946 bits (82), Expect = 1.051e-13 Identity = 34/132 (25.76%), Postives = 62/132 (46.97%), Query Frame = 2
Query: 1184 PDPENDT--RLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWLDSNFETHK--SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
PDP N+ R L II Q+ E I +++ N +L RSE+ + L ++ HK S T+++ ++ LTGH V +++D++ + + S D ++R+W+ +G + L H
Sbjct: 121 PDPPNNDFFRKLYPKII------QDLETIETNWRCGNH-ALHKIPCRSENSKGVYCL--QYDDHKIVSGLRDNTIKVWDKKSLACVKVLTGHTGSVLCLQYDENVIVTGSSDSTVRVWNVHAGDMLNTLIHH 243 HSP 3 Score: 54.299 bits (129), Expect = 1.324e-7 Identity = 61/256 (23.83%), Postives = 116/256 (45.31%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSM-KGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + +VSG D +I VW +++ + +K+L GH GS+ L+ + S D T+R+ ++ G L+ L+ ++ +R +E ++ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 163 NSKGVYCLQYDDHKIVSGLRDNTIKVWD-KKSLACVKVLTGHTGSVLCLQYDENVIVT--GSSDSTVRVWNVHAGDMLNTLI------HHCEAVLHLRFQE--GMMVTCSKDRSIAVWDMQSPTDISLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHRRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 397
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Nematostella
Match: EDO42306 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1V2]) HSP 1 Score: 49.6766 bits (117), Expect = 3.790e-12 Identity = 43/166 (25.90%), Postives = 72/166 (43.37%), Query Frame = 1
Query: 1612 GAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRI-HSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIG---YQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVF 2097
AV C+ + +VSG +D + VW E I L GH + SL+ T SLD ++R+ H+ G L LV +S+ S +E N + +G D T+++ D+ C+ + + + CL F S +I+ G ++ W+ F
Sbjct: 412 AAVRCVKYDGHRVVSGAYDFLVKVWDPETE-QCIHTLQGHTNRVYSLQFDGTYIVS--GSLDTSIRVWHAETGQCLHTLVGHQSLTSG--------MELRNNTLVSGNADSTVKIWDITTGQCLQTLAGPNKHQSAVTCLQFSSKFVITSSDDGTVKIWDLQTGEF 566 HSP 2 Score: 40.0466 bits (92), Expect = 3.790e-12 Identity = 20/65 (30.77%), Postives = 32/65 (49.23%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
S + TL++ T + L GH V + + + S S DG+LR+WD+ +G + L GH
Sbjct: 346 SGSTDRTLKVWNAETGYCMHTLYGHTSTVRCMDMHEEVVVSGSRDGTLRVWDTTTGNCLHVLVGH 410 HSP 3 Score: 52.373 bits (124), Expect = 5.826e-7 Identity = 51/254 (20.08%), Postives = 101/254 (39.76%), Query Frame = 1
Query: 1612 GAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRET 2373
G V+ S I+VSG D ++ VW+ E + + LYGH T+R +DM E ++ +G D T+R+ D +C++ + ++C+ + H ++SG + ++ W+ E + +Q T++ L + + SL D SI+ W+ + C+ TL GH+ + + ++ + S + D +++IW + +T
Sbjct: 332 GGVWSSQLSGHIIVSGSTDRTLKVWNAETGYCM-HTLYGHT---------------------STVR------------------------CMDMHEE----VVVSGSRDGTLRVWDTTTGNCLHVLVGHLAAVRCVKYDGHRVVSGAYDFLVKVWDPET----EQCIHTLQGHTNRVYSLQFDGTYIVSGSL-----DTSIRVWHAETGQCLHTLVGHQSLTSGMELRNNTLVSGNADSTVKIWDITTGQCLQT 526
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Nematostella
Match: EDO39072 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB92]) HSP 1 Score: 48.521 bits (114), Expect = 3.164e-10 Identity = 66/262 (25.19%), Postives = 111/262 (42.37%), Query Frame = 1
Query: 1612 GAVYCLDFSSQILVSGGWDMSIFVWSLE-----QNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKC--LYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRETH 2376
G V CL+ + LVSG D SI VW L S + GHM T L EK++S S D TL++ +K +T++ N+ ++ ++ +E++ I +G D TI++ + C+ + D + C L +ISG L+FW+ + + + I L + +A +D ++K W L S + TL H + L F D + S S D ++++W H +H
Sbjct: 197 GTVRCLNLNGNRLVSGSVDRSIKVWDLSFESYWSGASCKVTMVGHM--HTVRCLQVDDEKVVSGSYDKTLKVWDIKTGNCK--LTLRGHNA---AVLCVQFDESK--IVSGSYDNTIKVWSLVEGSCLMTLAGHHDAVTCLNLTLDRRKVISGSLDHNLKFWDLATG----KCIGTLDWIRSEGHTGVIRCLQSDSWRIVSAGDDKTLKMWSLESGQRLLTLRCHTDGVTCLQFNDYRIVSGSYDKTVKVWDFSPKHEFLSH 445 HSP 2 Score: 35.039 bits (79), Expect = 3.164e-10 Identity = 12/29 (41.38%), Postives = 21/29 (72.41%), Query Frame = 2
Query: 1442 GHLDGVTMVKFDKSRMFSSSLDGSLRIWD 1528
GH G++ V+FD +R+ S S D ++++WD
Sbjct: 152 GHTQGISCVQFDDTRIVSGSSDKTIKVWD 180 HSP 3 Score: 53.9138 bits (128), Expect = 1.890e-7 Identity = 48/168 (28.57%), Postives = 86/168 (51.19%), Query Frame = 1
Query: 1588 KLNYI*NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEP-TGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNP 2088
KL + AV C+ F +VSG +D +I VWSL + S + L GH ++T L L + K+IS SLD L+ + K + T+ + SE TG+I ++ +++ G DKT+++ ++ + + D + CL F + ++SG + ++ W+ +P
Sbjct: 275 KLTLRGHNAAVLCVQFDESKIVSGSYDNTIKVWSLVEG-SCLMTLAGHHDAVTCLNLTLDRRKVISGSLDHNLKFWDLATGKC--IGTLDWIRSEGHTGVIRCLQSDSWRIVSAGD-DKTLKMWSLESGQRLLTLRCHTDGVTCLQFNDYRIVSGSYDKTVKVWDFSP 438
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Nematostella
Match: EDO48004 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKK9]) HSP 1 Score: 57.3806 bits (137), Expect = 1.726e-8 Identity = 72/290 (24.83%), Postives = 122/290 (42.07%), Query Frame = 1
Query: 1588 KLNYI*NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXA----------SLDGTLRIH-------------------SMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCD--------KTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWR 2346
K ++ + G V+ L ++L SG D +I VW + +K L GH G + +L K SA +L+ IH S+K K+ NL T++ V E TG+ R L+A CD +TI+L D+D L+C+ + + L +I G + +Q W+ N E + L + S R L++A D S++ W L + TC++TL H+GS++ L + S ++D ++++W+
Sbjct: 392 KGTFVGHTGPVWALCVHGELLFSGSSDKTIKVWDTLTTYKCVKTLEGHTGIVLALCTHDKKLFSGSADCVINIWSIETLELLDSIHGHENPVCTLVTKRNILFSGSLKKIKVWNLDTLELVR-EMTGLNHW----VRALVA---CDSYLYSGSYQTIKLWDLDTLECVRVLQTSGGSVYSLAVTKEYIICGTYENCIQVWDVNTHKLIETLNGHVGTV----YALVVLSAPGQTR-LFSASYDRSLRVWNLETFTCLQTLLRHQGSVSTLALSKGRIFSGAVDSTVKVWQ 668
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Medaka
Match: fbxw11a (F-box and WD repeat domain containing 11 [Source:NCBI gene;Acc:101174029]) HSP 1 Score: 59.6918 bits (143), Expect = 2.287e-13 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L F++ ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+ +Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 307 AVLHLRFANGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD-------------LQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 502 HSP 2 Score: 36.1946 bits (82), Expect = 2.287e-13 Identity = 22/84 (26.19%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I T+E LTGH V +++D+ + + S D ++R+W+ +G + L H
Sbjct: 221 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWEVTTGEVLNTLIHH 304 HSP 3 Score: 53.9138 bits (128), Expect = 5.687e-7 Identity = 62/256 (24.22%), Postives = 111/256 (43.36%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRI-HSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W +Q +KIL GH GS+ L+ + S D T+R+ G L+ L+ ++ +R L+ T D++I + DM I +G++ + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 224 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KQTLECLKILTGHTGSVLCLQYDERVIVT--GSSDSTVRVWEVTTGEVLNTLI------HHNEAVLHLRF--ANGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRA-AVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 458
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Medaka
Match: fbxw11a (F-box and WD repeat domain containing 11 [Source:NCBI gene;Acc:101174029]) HSP 1 Score: 59.6918 bits (143), Expect = 2.477e-13 Identity = 58/245 (23.67%), Postives = 107/245 (43.67%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQ--NFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIW 2343
AV L F++ ++V+ D SI VW + + SL ++L GH ++ + AS D T+++ S + ++++N GI ++ + L+ +G D TIRL D++ C+ + +++++C+ F + ++SG + G ++ W+ +Q D + P AS C+RTL H G + L F + + SSS D +I IW
Sbjct: 342 AVLHLRFANGLMVTCSKDRSIAVWDMASPTDISLRRVLVGHRAAVNVVDFDDKYIVS--ASGDRTIKVWSTSTCEF-----VRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD-------------LQAALDPRAP---------------------------ASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIW 537 HSP 2 Score: 36.1946 bits (82), Expect = 2.477e-13 Identity = 22/84 (26.19%), Postives = 41/84 (48.81%), Query Frame = 2
Query: 1316 RSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
RSE+ + L + E S +++I T+E LTGH V +++D+ + + S D ++R+W+ +G + L H
Sbjct: 256 RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKQTLECLKILTGHTGSVLCLQYDERVIVTGSSDSTVRVWEVTTGEVLNTLIHH 339 HSP 3 Score: 53.5286 bits (127), Expect = 6.395e-7 Identity = 62/256 (24.22%), Postives = 111/256 (43.36%), Query Frame = 1
Query: 1606 NQGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRI-HSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCI----YNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKS 2358
N VYCL + + ++SG D SI +W +Q +KIL GH GS+ L+ + S D T+R+ G L+ L+ ++ +R L+ T D++I + DM I +G+ + + + F ++S ++ W+T+ F V T I L Y R + + +D +I+ W + C+R L GH+ + + F + + S + DG I++W L+ +
Sbjct: 259 NSKGVYCLQYDDEKIISGLRDNSIKIWD-KQTLECLKILTGHTGSVLCLQYDERVIVT--GSSDSTVRVWEVTTGEVLNTLI------HHNEAVLHLRF--ANGLMVTCSKDRSIAVWDMASPTDISLRRVLVGH-RAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEF---------VRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAA 493
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Medaka
Match: fbxw7 (F-box and WD repeat domain containing 7 [Source:NCBI gene;Acc:101155087]) HSP 1 Score: 43.5134 bits (101), Expect = 1.590e-10 Identity = 39/166 (23.49%), Postives = 74/166 (44.58%), Query Frame = 1
Query: 1612 GAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNI-GYQK--DVIKCLYFQSHLLISGGHSGFLQFWNTNPSVF 2097
AV C+ + + +VSG +D + VW E + + L GH L ++S SLD ++R+ ++ G + L +S+ S +E N++ +G D T+++ D+ C+ + G K + CL F + +I+ G ++ W+ F
Sbjct: 573 AAVRCVQYDGRRVVSGAYDFMVKVWDPETE-TCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG--------MELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEF 727 HSP 2 Score: 42.743 bits (99), Expect = 1.590e-10 Identity = 21/65 (32.31%), Postives = 33/65 (50.77%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
S + TL++ T E + L GH V + + R+ S S D +LR+WD +G+ + L GH
Sbjct: 507 SGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 571 HSP 3 Score: 58.9214 bits (141), Expect = 2.001e-8 Identity = 57/252 (22.62%), Postives = 115/252 (45.63%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRET 2373
+ CL F +VSG D ++ VWS L + L GH G + S ++ + S D TL++ + + I ++ + + M + E R + +G D T+R+ D++ C++ + ++C+ + ++SG + ++ W+ E + +Q T++ L + + SL D SI+ W + + CI TL GH+ + + D+++ S + D +++IW +K +T
Sbjct: 455 ITCLQFCGNRIVSGSDDNTLKVWSAVTGKCL-RTLVGHTGGVWSSQMRENIIIS--GSTDRTLKV-----WNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPE----TETCLHTLQGHTNRVYSLQFDGIHVVSGSL-----DTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQT 687
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Medaka
Match: fbxw7 (F-box and WD repeat domain containing 7 [Source:NCBI gene;Acc:101155087]) HSP 1 Score: 43.8986 bits (102), Expect = 1.815e-10 Identity = 39/166 (23.49%), Postives = 74/166 (44.58%), Query Frame = 1
Query: 1612 GAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMK-GFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNI-GYQK--DVIKCLYFQSHLLISGGHSGFLQFWNTNPSVF 2097
AV C+ + + +VSG +D + VW E + + L GH L ++S SLD ++R+ ++ G + L +S+ S +E N++ +G D T+++ D+ C+ + G K + CL F + +I+ G ++ W+ F
Sbjct: 348 AAVRCVQYDGRRVVSGAYDFMVKVWDPETE-TCLHTLQGHTN--RVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG--------MELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPHKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEF 502 HSP 2 Score: 42.3578 bits (98), Expect = 1.815e-10 Identity = 21/65 (32.31%), Postives = 33/65 (50.77%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
S + TL++ T E + L GH V + + R+ S S D +LR+WD +G+ + L GH
Sbjct: 282 SGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGH 346 HSP 3 Score: 60.4622 bits (145), Expect = 5.634e-9 Identity = 57/252 (22.62%), Postives = 115/252 (45.63%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLKKSHSRET 2373
+ CL F +VSG D ++ VWS L + L GH G + S ++ + S D TL++ + + I ++ + + M + E R + +G D T+R+ D++ C++ + ++C+ + ++SG + ++ W+ E + +Q T++ L + + SL D SI+ W + + CI TL GH+ + + D+++ S + D +++IW +K +T
Sbjct: 230 ITCLQFCGNRIVSGSDDNTLKVWSAVTGKCL-RTLVGHTGGVWSSQMRENIIIS--GSTDRTLKV-----WNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPET----ETCLHTLQGHTNRVYSLQFDGIHVVSGSL-----DTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQT 462 HSP 4 Score: 39.6614 bits (91), Expect = 2.425e-6 Identity = 19/70 (27.14%), Postives = 36/70 (51.43%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHKVKSY 1582
S + TL++ + T + + L GH+ V V++D R+ S + D +++WD + + L GH + Y
Sbjct: 322 SGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVY 391 HSP 5 Score: 31.9574 bits (71), Expect = 2.425e-6 Identity = 33/124 (26.61%), Postives = 58/124 (46.77%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNI 1989
VY L F +VSG D SI VW +E + I L GH + ++L +A D T++I +K + L T++ + + + ++ +N + T D T++L D+ + I N+
Sbjct: 390 VYSLQFDGIHVVSGSLDTSIRVWDVETG-NCIHTLTGHQSLTSGMELKDNILVSGNA--DSTVKIWDIKTGQC--LQTLQGPHKHQSAVTCLQFN--KNFVITSSDDGTVKLWDLKTGEFIRNL 506
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Medaka
Match: ENSORLT00000003546.2 (F-box/WD repeat-containing protein 7 [Source:NCBI gene;Acc:101171440]) HSP 1 Score: 58.9214 bits (141), Expect = 1.330e-8 Identity = 54/245 (22.04%), Postives = 111/245 (45.31%), Query Frame = 1
Query: 1618 VYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRLK 2352
+ CL FS ++VSG D ++ VWS L + L GH G + ++ S D TLR+ + ++ + ++ + + M + R + +G D T+R+ ++ C + + ++C+ + ++SGG+ ++ W+ E + +Q T++ L + F SL D SI+ W + C+ TL GH+ + + D+++ S + D ++R+W ++
Sbjct: 229 ITCLQFSGDLIVSGSDDNTLKVWSAVTGKCL-QTLTGHTGGVWCSQMAVATVIS--GSTDRTLRV-----WDAESGECVHTLYGHTSTVRCMHLHGNR--VVSGSRDTTLRVWNVTTGQCEHVLTGHVAAVRCVQYDGRRVVSGGYDYMVKVWDPET----EVCLHTLQGHTNRVYSLQFDGAFVVSGSL-----DTSIRVWDAETGGCVHTLTGHQSLTSGMELRDNILVSGNADSTVRVWDIR 454 HSP 2 Score: 52.373 bits (124), Expect = 1.878e-6 Identity = 33/116 (28.45%), Postives = 56/116 (48.28%), Query Frame = 2
Query: 1373 SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH----KVKSYLSN*IISKIREQFIVWISLLRFWFQVDGTCQYLYGLSSKISA 1708
S + TL++ +T + LTGH GV + + + S S D +LR+WD+ SG + LYGH + N ++S R+ + LR W G C+++ L+ ++A
Sbjct: 241 SGSDDNTLKVWSAVTGKCLQTLTGHTGGVWCSQMAVATVISGSTDRTLRVWDAESGECVHTLYGHTSTVRCMHLHGNRVVSGSRD------TTLRVWNVTTGQCEHV--LTGHVAA 348
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Planmine SMEST
Match: SMESG000025496.1 (SMESG000025496.1) HSP 1 Score: 505.368 bits (1300), Expect = 0.000e+0 Identity = 276/279 (98.92%), Postives = 276/279 (98.92%), Query Frame = 2
Query: 746 MDSIPTKILENIFYYFSPDELIKASLVNKQWLSVALNNGLWENHCATLGKSLGFTKFVEMMEENIADSARINWFEIYKAIRKLSRQNNSVIDVKNNIRKSKITFYEAAXXXXXXXXXXXFLXXXXXXXXXXXXXXKTSIKFNNVLDPDPENDTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHKVKSY 1582
MDSIPTKILENIFYYFSPDELIKASLVNKQWLSVALNNGLWENHCATLGKSLGFTKFVEMMEENIADSARINWFEIYKAIRKLSRQNNSVIDVKNNIRKSKITFYEAAKSVKIKSKVSKFLSNRSTSVNSSRRASKTSIKFNNVLDPDPENDTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHK Y
Sbjct: 1 MDSIPTKILENIFYYFSPDELIKASLVNKQWLSVALNNGLWENHCATLGKSLGFTKFVEMMEENIADSARINWFEIYKAIRKLSRQNNSVIDVKNNIRKSKITFYEAAKSVKIKSKVSKFLSNRSTSVNSSRRASKTSIKFNNVLDPDPENDTRLLMKPIIGQLKQFQNSEEIAIDFKSSNLVSLVDSKKRSESKFNLKWLDSNFETHKSAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHKGAVY 279 HSP 2 Score: 351.288 bits (900), Expect = 0.000e+0 Identity = 186/187 (99.47%), Postives = 187/187 (100.00%), Query Frame = 1
Query: 1609 QGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLF 2169
+GAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGSITSLKLLKTKEKLISASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLF
Sbjct: 275 KGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGSITSLKLLKTKEKLISASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLF 461 HSP 3 Score: 28.8758 bits (63), Expect = 0.000e+0 Identity = 11/11 (100.00%), Postives = 11/11 (100.00%), Query Frame = 3
Query: 2166 FLSYEKFMDCP 2198
FLSYEKFMDCP
Sbjct: 461 FLSYEKFMDCP 471
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Planmine SMEST
Match: SMESG000025494.1 (SMESG000025494.1) HSP 1 Score: 392.504 bits (1007), Expect = 1.668e-132 Identity = 196/196 (100.00%), Postives = 196/196 (100.00%), Query Frame = 2
Query: 140 MSEIFIKTVFKFQKLKIQEKKFVLCSFIGLIDRESLYSLKQTLEPFNLSKFQNQFGTIDLGNKNEDEDEIPNLQLISEKLVNEILSSSVRIVENEFLSSNSLEKFILNTNNSKLIDSFALPPIEHKHAVKLDRNLRGQSQRSKKQLKGFPDTIKLLIKNLATEFSTKIDKYKILIEILCAENWDIQFHVYQCVKSR 727
MSEIFIKTVFKFQKLKIQEKKFVLCSFIGLIDRESLYSLKQTLEPFNLSKFQNQFGTIDLGNKNEDEDEIPNLQLISEKLVNEILSSSVRIVENEFLSSNSLEKFILNTNNSKLIDSFALPPIEHKHAVKLDRNLRGQSQRSKKQLKGFPDTIKLLIKNLATEFSTKIDKYKILIEILCAENWDIQFHVYQCVKSR
Sbjct: 1 MSEIFIKTVFKFQKLKIQEKKFVLCSFIGLIDRESLYSLKQTLEPFNLSKFQNQFGTIDLGNKNEDEDEIPNLQLISEKLVNEILSSSVRIVENEFLSSNSLEKFILNTNNSKLIDSFALPPIEHKHAVKLDRNLRGQSQRSKKQLKGFPDTIKLLIKNLATEFSTKIDKYKILIEILCAENWDIQFHVYQCVKSR 196
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Planmine SMEST
Match: SMESG000011456.1 (SMESG000011456.1) HSP 1 Score: 53.1434 bits (126), Expect = 1.235e-14 Identity = 42/157 (26.75%), Postives = 77/157 (49.04%), Query Frame = 1
Query: 1609 QGAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
Q A+ C+ + ++VSG D +I +W N + L+GH+ + L L ++IS S D TL+ ++ K + TI + SE + ++ R +G DKTI++ D++ ++ KD + CL F + +L+SG + + W+
Sbjct: 344 QDAILCVQYDDSVIVSGSLDKTIKIWLF--NGECLFTLHGHVDPVACLHLDYKHNRIISGSHDNTLKFWDIRNKKC--IRTIDWIESEGHKRVVRCLQADRYKFISGSDDKTIKVWDIENGTRLHTYQGHKDGVSCLQFNNEMLVSGSYDHSVILWD 496 HSP 2 Score: 46.595 bits (109), Expect = 1.235e-14 Identity = 20/45 (44.44%), Postives = 29/45 (64.44%), Query Frame = 2
Query: 1436 LTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGHK 1570
LTGHL+ V ++ D ++ S S DGSL++W +G IR L GH+
Sbjct: 300 LTGHLNSVRCLQADHDKIVSGSYDGSLKVWCMATGELIRTLRGHQ 344 HSP 3 Score: 51.6026 bits (122), Expect = 2.037e-6 Identity = 54/222 (24.32%), Postives = 106/222 (47.75%), Query Frame = 1
Query: 1648 LVSGGWDMSIFVWSL--EQNFSLI---KILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLY--FQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHF 2292
LVSG D +I +W+L ++S I L GH+ S+ L+ K S DG+L++ M +L I+++ I+ ++ +++ +I +G DKTI++ + +C++ + D + CL+ ++ + +ISG H L+FW+ + ++ + I + + L + +D +IK W + + T + T GHK ++ L F
Sbjct: 271 LVSGSNDKTIKIWALAARNDWSSIICRATLTGHLNSVRCLQADHDKIVS--GSYDGSLKVWCMATGEL-----IRTLRGHQDAILCVQYDDS--VIVSGSLDKTIKIWLFNG-ECLFTLHGHVDPVACLHLDYKHNRIISGSHDNTLKFWD----IRNKKCIRTIDWIESEGHKRVVRCLQADRYKFISGSDDKTIKVWDIENGTRLHTYQGHKDGVSCLQF 478
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Planmine SMEST
Match: SMESG000052999.1 (SMESG000052999.1) HSP 1 Score: 55.0694 bits (131), Expect = 1.096e-12 Identity = 39/157 (24.84%), Postives = 78/157 (49.68%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSL--EQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWN 2079
AV L F+ ILV+ D SI VW + + L ++L GH ++ + + AS D T+++ + + + + ++N GI ++ NL+ +G D TIRL ++ C+ + +++++C+ F S ++SG + G ++ W+
Sbjct: 342 AVLHLRFAHSILVTCSKDRSIAVWDMFAPSDIRLRRVLVGHRAAVNVVDFDQKNIVS--ASGDRTIKVWNTQSCEF-----LHTMNGHRRGIACLQYRN--NLVVSGSSDNTIRLWQIETGTCLRTLEGHEELVRCIRFDSKYIVSGAYDGKIKVWD 489 HSP 2 Score: 38.1206 bits (87), Expect = 1.096e-12 Identity = 23/93 (24.73%), Postives = 44/93 (47.31%), Query Frame = 2
Query: 1328 KFNLKWLDSNFETHK-------------SAAAGETLQIRKVLTIENCYKLTGHLDGVTMVKFDKSRMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
K+NLK ++ + E+ K S ++++ T+E LTGH+ V +++D + + S S D ++R+W S + +Y H
Sbjct: 247 KYNLKKIECHSESSKGVYCLQYDDKKIVSGLRDNSIKVWDARTLECVRVLTGHVGSVLCLQYDNNVIISGSSDSTVRVWSLSSWTCVNTIYHH 339 HSP 3 Score: 53.9138 bits (128), Expect = 4.345e-7 Identity = 59/250 (23.60%), Postives = 111/250 (44.40%), Query Frame = 1
Query: 1615 AVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSMKGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDM-----DRLDCIYNIGYQKDVIKCLYFQSHLLISGGHSGFLQFWNTNPSVFHEASMAEIQVFTDKKLPLSIESLFYHMRSLWTAHNDGSIKEWYLASMTCIRTLYGHKGSIAYLHFFXXXXXXXXXXXXIRIWRL 2349
VYCL + + +VSG D SI VW + +++L GH+GS+ L+ S D T+R+ S+ + + ++ ++ +R + ++ T D++I + DM RL + +G++ + + F ++S ++ WNT F + T I L Y + + +D +I+ W + + TC+RTL GH+ + + F + S + DG I++W L
Sbjct: 262 GVYCLQYDDKKIVSGLRDNSIKVWD-ARTLECVRVLTGHVGSVLCLQYDNNVIIS--GSSDSTVRVWSLSSW-----TCVNTIYHHCEAVLHLRFAHS--ILVTCSKDRSIAVWDMFAPSDIRLRRVL-VGHRA-AVNVVDFDQKNIVSASGDRTIKVWNTQSCEF---------LHTMNGHRRGIACLQYRNNLVVSGSSDNTIRLWQIETGTCLRTLEGHEELVRCIRFDSKYIVSGAYDGKIKVWDL 490
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Planmine SMEST
Match: SMESG000065201.1 (SMESG000065201.1) HSP 1 Score: 44.669 bits (104), Expect = 9.936e-6 Identity = 46/167 (27.54%), Postives = 74/167 (44.31%), Query Frame = 1
Query: 1612 GAVYCLDFSSQILVSGGWDMSIFVWSLEQNFSLIKILYGHMGXXXXXXXXXXXXXXXXASLDGTLRIHSM-KGFKLDNLVTIKSVNSEPTGIIDMRIEETRNLIATGLCDKTIRLIDMDRLDCIYN-IGYQKDVIKCLYFQ---SHLLISGGHSGFLQFWNTNPSVF 2097
GA+ C+ SS +VSG +D ++ VW + +L GH + ++SASLD T+R+ + G LV KS+ S M + +L+ +G D TIR+ + +CI +G Q Q ++S SG ++ WN + VF
Sbjct: 220 GAIRCVQASSVCVVSGSYDCTVRVWDIITGICAF-VLNGHTD--RVYTIHLGATVILSASLDTTIRVWDIHTGICTHVLVGHKSLTS------GMVMNSDESLVVSGNADSTIRVWRVSTGECILELLGQQAHTSPLTGIQIVLDKFIVSSELSGTVKLWNLDDGVF 377 HSP 2 Score: 24.6386 bits (52), Expect = 9.936e-6 Identity = 10/28 (35.71%), Postives = 16/28 (57.14%), Query Frame = 2
Query: 1484 RMFSSSLDGSLRIWDSISGRSIRKLYGH 1567
++ S S D ++RIWD + + L GH
Sbjct: 191 KLISGSRDSTIRIWDVFTRKCDHLLEGH 218 The following BLAST results are available for this feature:
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of F-box and WD-40 domain-containing protein 1/11 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015580 ID=SMED30015580|Name=F-box and WD-40 domain-containing protein 1/11|organism=Schmidtea mediterranea sexual|type=transcript|length=2418bpback to top protein sequence of SMED30015580-orf-1 >SMED30015580-orf-1 ID=SMED30015580-orf-1|Name=SMED30015580-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=485bp MSEIFIKTVFKFQKLKIQEKKFVLCSFIGLIDRESLYSLKQTLEPFNLSKback to top protein sequence of SMED30015580-orf-2 >SMED30015580-orf-2 ID=SMED30015580-orf-2|Name=SMED30015580-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=250bp MSIFVWSLEQNFSLIKILYGHMGSITSLKLLKTKEKLISASLDGTLRIHSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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