Kinase

Overview
NameKinase
Smed IDSMED30015577
Length (bp)976
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Kinase (SMED30015577) t-SNE clustered cells

Violin plots show distribution of expression levels for Kinase (SMED30015577) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Kinase (SMED30015577) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Kinase (SMED30015577) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30015577

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30015577SMESG000022299.1 dd_Smed_v4_3701_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30015577SMESG000022299.1 dd_Smed_v4_3701_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30015577SMESG000022299.1 dd_Smed_v4_3701_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30015577SMESG000022299.1 dd_Smed_v4_3701_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30015577SMESG000022299.1 dd_Smed_v4_3701_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015577SMESG000022299.1 Contig41225newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015577SMESG000022299.1 Contig41225uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Kinase vs. Ensembl Human
Match: IPMK (inositol polyphosphate multikinase [Source:HGNC Symbol;Acc:HGNC:20739])

HSP 1 Score: 94.3597 bits (233), Expect = 4.882e-21
Identity = 51/138 (36.96%), Postives = 82/138 (59.42%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIK---VHEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS 711
            +LY+ +ED+ ++F  P + DVKIG+ SY+P  SSEK   ++ KY   E +GFL+ G++   VH  +    ++++GRSL + E    G+  F    +   K      I  ++K+L+WF +QKQ+ F ASS+L  YE +S
Sbjct:  125 DLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTK-ETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQKQLNFYASSLLFVYEGSS 261
[Close]
BLAST of Kinase vs. Ensembl Human
Match: IP6K3 (inositol hexakisphosphate kinase 3 [Source:HGNC Symbol;Acc:HGNC:17269])

HSP 1 Score: 51.6026 bits (122), Expect = 8.531e-7
Identity = 44/183 (24.04%), Postives = 86/183 (46.99%), Query Frame = 1 
Query:  301 KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRES--VGFLITGIKVHEPTPLFF---DRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS----SXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHV 822
            K + ++ +E+++ Q+  P V D+K+G   +    S EKK   + K     S  +G  I G++V++    +F   D+Y+GR L+  E + + +  FL    +  + L    +  L+ LL     Q    F +SS+L+ Y+       +  + + +   +   G    G   ++V +++IDF H 
Sbjct:  194 KRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSV-EGFRQALYQFLHNGSHLRRELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQEPPERAPGSPHPHEAPQAAHGSSPGGL--TKVDIRMIDFAHT 373
[Close]
BLAST of Kinase vs. Ensembl Human
Match: IP6K3 (inositol hexakisphosphate kinase 3 [Source:HGNC Symbol;Acc:HGNC:17269])

HSP 1 Score: 51.6026 bits (122), Expect = 8.531e-7
Identity = 44/183 (24.04%), Postives = 86/183 (46.99%), Query Frame = 1 
Query:  301 KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRES--VGFLITGIKVHEPTPLFF---DRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS----SXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHV 822
            K + ++ +E+++ Q+  P V D+K+G   +    S EKK   + K     S  +G  I G++V++    +F   D+Y+GR L+  E + + +  FL    +  + L    +  L+ LL     Q    F +SS+L+ Y+       +  + + +   +   G    G   ++V +++IDF H 
Sbjct:  194 KRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSV-EGFRQALYQFLHNGSHLRRELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQEPPERAPGSPHPHEAPQAAHGSSPGGL--TKVDIRMIDFAHT 373
[Close]
BLAST of Kinase vs. Ensembl Celegans
Match: ipmk-1 (Kinase [Source:UniProtKB/TrEMBL;Acc:O62519])

HSP 1 Score: 56.9954 bits (136), Expect = 4.140e-9
Identity = 40/151 (26.49%), Postives = 77/151 (50.99%), Query Frame = 1 
Query:  271 HGIQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPL--FFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQF----ITNLQKLLEWFNHQKQMGFIASSILMAYES 705
            +GIQ      ++  ++ +ED+   ++ P++ D+K+G+V+Y+P    EK   E  KY  +  +G  I G ++H         D+  G+S ++  V T G++ F      R++   NQ     +  L+ +  +F  Q+ + F ASS+L  +E+
Sbjct:  105 YGIQTIFVDGQDREFLAMEDVTIGYQRPAILDLKMGQVTYDPIAKPEKIEKERIKYPPQAKMGMRILGYRIHRSDNQVEVRDKDWGKSFDETTVET-GLREFFSA---RSEADLNQVLLEALDKLKIIKNFFETQRSLQFFASSLLFVFEA 251
[Close]
BLAST of Kinase vs. Ensembl Fly
Match: Ipk2 (gene:FBgn0031267 transcript:FBtr0078074)

HSP 1 Score: 86.2705 bits (212), Expect = 6.158e-19
Identity = 64/225 (28.44%), Postives = 110/225 (48.89%), Query Frame = 1 
Query:  298 QKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKY-KWRESVGFLITGIKVHEP--------TPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAK-------YLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQE--INGYHDSE------VLVKLIDFTHVLPITEH--DTNCIYALNSLIKYFHRV 894
            ++E  ++ +EDL   +  P V DVK+GK +++P  S  K+  E  KY   ++ +G  + G +V+ P        T L   + +G+SLN  E + + + +F     + +K        L  + +  LQ++L WF  Q+ + F ASS+L+ Y+ +            +  D  +  INGYH ++      V VK+IDF HV P  +   D N ++ L SLI+    +
Sbjct:   95 RRERTFLRLEDLTRSYAKPCVMDVKMGKRTWDPESSPNKRKVEEAKYVMCKQKLGLCLPGFQVYLPKEEHTQETTILRHGKDYGKSLNV-EGFKQTMALFFNASTSDSKSRRAGCELLLKEVLRQLQEILAWFQRQRLLHFYASSLLICYDYS------------RLADPPKPLINGYHQNDDDPATWVRVKMIDFAHVYPAEQGLPDENYMFGLQSLIEVVQSI 306
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: ipmka (inositol polyphosphate multikinase a [Source:ZFIN;Acc:ZDB-GENE-090312-161])

HSP 1 Score: 94.7449 bits (234), Expect = 3.468e-22
Identity = 62/226 (27.43%), Postives = 107/226 (47.35%), Query Frame = 1 
Query:  310 LYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVH---EPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSX-------------XXXXXXXXRKWCDGQEINGY---------------------HDSEVLVKLIDFTHVLPITEHDTNCIYALNSLI 876
            LY+ +ED+  +F  P + DVKIG+ SY+P  S EK+  +I KY   E +GFL+ G++V+     + +  D+++GRSL +D +   G+  F     +  +   +  I+ ++++L WF  Q Q+ F ASS+L+ YE +                 N + ++  +       NG                       +  V V++IDF HV P    D + +Y L +L+
Sbjct:   41 LYLKLEDVTRRFLRPCIMDVKIGRKSYDPFASKEKRQEQISKYPLMEEIGFLLLGMRVYLINSDSYITHDQFYGRSLGKDTI-KNGLSRFFHNGQDLRRGAISLIISKIRRILRWFETQTQLHFYASSLLLVYEGSPHTLDGQKHKQTQHRPQNNFSSHQSRSTHTPNTNGTLGGAGGEDDGDVGVEDKKQFGQEEAVEVRMIDFAHVFPSDTADQSYMYGLRNLL 265
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: ipmka (inositol polyphosphate multikinase a [Source:ZFIN;Acc:ZDB-GENE-090312-161])

HSP 1 Score: 94.7449 bits (234), Expect = 7.244e-22
Identity = 61/226 (26.99%), Postives = 106/226 (46.90%), Query Frame = 1 
Query:  310 LYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVH---EPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXX-------------XXXXRKWCDGQEINGY---------------------HDSEVLVKLIDFTHVLPITEHDTNCIYALNSLI 876
            LY+ +ED+  +F  P + DVKIG+ SY+P  S EK+  +I KY   E +GFL+ G++V+     + +  D+++GRSL +D +   G+  F     +  +   +  I+ ++++L WF  Q Q+ F ASS+L+ YE +    +                ++  +       NG                       +  V V++IDF HV P    D + +Y L +L+
Sbjct:   87 LYLKLEDVTRRFLRPCIMDVKIGRKSYDPFASKEKRQEQISKYPLMEEIGFLLLGMRVYLINSDSYITHDQFYGRSLGKDTI-KNGLSRFFHNGQDLRRGAISLIISKIRRILRWFETQTQLHFYASSLLLVYEGSPHTLDGQKHKQTQHRPQNNFSSHQSRSTHTPNTNGTLGGAGGEDDGDVGVEDKKQFGQEEAVEVRMIDFAHVFPSDTADQSYMYGLRNLL 311
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: ipmkb (inositol polyphosphate multikinase b [Source:ZFIN;Acc:ZDB-GENE-061215-5])

HSP 1 Score: 93.5893 bits (231), Expect = 4.403e-21
Identity = 50/139 (35.97%), Postives = 78/139 (56.12%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRY---HGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASS 714
            +LY+ +ED+  +F+ P + DVKIG+ SY+P  S EK+  +I KY   E +GFL+ G++V++     FD Y   +GR L +D +  +G+  F        K      I  +QK+L+WF  Q +  F ASS+L  YE   +
Sbjct:  116 DLYLKLEDVTRRFQKPCIMDVKIGQRSYDPFASQEKREQQIRKYPLMEEIGFLVLGMRVYKVGSDGFDTYDQHYGRGLGKDTI-MEGLSKFFYNGETLRKDAITASILKVQKILQWFEGQSRFNFYASSLLFVYEGVCA 253
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: ip6k2a (inositol hexakisphosphate kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030131-760])

HSP 1 Score: 55.8398 bits (133), Expect = 2.645e-8
Identity = 36/147 (24.49%), Postives = 72/147 (48.98%), Query Frame = 1 
Query:  277 IQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKW--RESVGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYE 702
            ++ N K++ +  +I +E+L + + +P V D+K+G   +    S EKK  +I K +     S+G  + G++V+ P     +F ++YHGR L     + + I  F        + L +  +  L+ +       +   F +SS+L+ Y+
Sbjct:  189 MKENAKHRNQYKFILLENLTWSYAVPCVLDLKMGTRQHGDDASEEKKAMQIRKCQQSTSASIGVRLCGMQVYHPATGQLMFMNKYHGRKLTLSG-FKEAIFQFFHDGRRLRRELLSPVLRRLRDMQAALEACESYRFYSSSLLIIYD 334
[Close]
BLAST of Kinase vs. Ensembl Zebrafish
Match: ip6k2b (inositol hexakisphosphate kinase 2b [Source:ZFIN;Acc:ZDB-GENE-040718-85])

HSP 1 Score: 54.6842 bits (130), Expect = 6.067e-8
Identity = 41/151 (27.15%), Postives = 79/151 (52.32%), Query Frame = 1 
Query:  277 IQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKW--RESVGFLITGIKV-HEPTP--LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITN-LQKLLEW---FNHQKQMGFIASSILMAYE 702
            ++ N K++ ++ +I +E+L +++++P V D+K+G   +    S EKK  +I K +     S+G  + G+++ H  T   +F ++YHGR L+       G K  L    +  + L  + +T  LQ+L E        +   F +SS+L+ Y+
Sbjct:  186 MKENSKHRNQHKFILLENLTWRYRVPCVLDLKMGTRQHGDDASEEKKANQIRKCQQSTSSSIGVRLCGMQMFHNATGQLIFMNKYHGRKLS-----LAGFKEALCQFFSDGRVLRRELLTPVLQRLREMRAVLEACESYRFFSSSLLIIYD 331
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: IPMK (inositol polyphosphate multikinase [Source:NCBI gene;Acc:100485175])

HSP 1 Score: 86.2705 bits (212), Expect = 2.893e-18
Identity = 48/141 (34.04%), Postives = 83/141 (58.87%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFF---DRYHGRSLNQDEVYTKGIKMFLGPDHNRAKY---LANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS 711
            +LY+ +ED+  +F  P + D+KIG+ SY+P  S+EK   ++ KY   E +GFL+ G++V+      +   ++++GRSL ++ V  +G+  F    HN A+      ++ I  +Q +L+WF  Q+   F ASS+L  YE +S
Sbjct:  108 DLYLKLEDITRKFNKPCIMDIKIGQKSYDPFASAEKIQQQVSKYPLMEEIGFLVLGMRVYNVLSDSYETQNQHYGRSLTKETV-KEGVSKFF---HNGARLRNDAVSECIRKVQNILQWFEFQENYHFYASSLLFVYEGSS 244
[Close]
BLAST of Kinase vs. Ensembl Xenopus
Match: sall1 (spalt-like transcription factor 1 [Source:Xenbase;Acc:XB-GENE-491393])

HSP 1 Score: 53.9138 bits (128), Expect = 1.493e-7
Identity = 55/255 (21.57%), Postives = 110/255 (43.14%), Query Frame = 1 
Query:  232 PQTLKEYTYQVGGHGIQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRES--VGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQE---------------INGYHDSEVLVKLIDFTHV---------LPITEHDTNCIYALNSLIKYFHRVKTDHN 909
            P ++K +  Q+    ++ N K++ +  +I +E+L  + ++P V D+K+G   +    + EKK  +I K +   S  +G  + G++V++      +F ++YHGR L+  + + + +  F     N  + L    +  L +L      Q    F +SS+L+ Y+   +      ++     D  E                N    S V V++IDF H          +     DT  I+ L +LI     ++ +++
Sbjct:  177 PWSMKCHQQQL--QRMKENAKHRNQYKFILLENLTCRHQVPCVLDLKMGTRQHGDDATEEKKANQIRKCQQSTSAIIGVRVCGMQVYQTGTGQLMFMNKYHGRKLSV-QGFKEALYQFFHNGKNLRRELIEPVLKKLTELKVVLETQDSYRFYSSSLLIIYDGKETQEVPMDSDPEDLEDLSEESSDESAGAYAYKPSKNKPSASTVDVRMIDFAHTTCKFYGEDSIVHEGQDTGYIFGLQNLIAIIKEIRDENS 428
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Ipmk (inositol polyphosphate multikinase [Source:MGI Symbol;Acc:MGI:1916968])

HSP 1 Score: 90.8929 bits (224), Expect = 4.470e-20
Identity = 50/150 (33.33%), Postives = 85/150 (56.67%), Query Frame = 1 
Query:  271 HGIQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKV---HEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS 711
            +G+ +       ++Y+ +ED+ ++F  P + DVKIG+ SY+P  SSEK   ++ KY   E +GFL+ G++V   H  +    ++++GR L + E   +G+  F        K      I  ++K+L+WF +QKQ+ F ASS+L  YE +S
Sbjct:   97 YGVWSPPTAPNADVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTK-ETLKEGVSKFFHNGFCLRKDAIAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSS 245
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Ipmk (inositol polyphosphate multikinase [Source:MGI Symbol;Acc:MGI:1916968])

HSP 1 Score: 90.1225 bits (222), Expect = 7.990e-20
Identity = 49/138 (35.51%), Postives = 81/138 (58.70%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKV---HEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS 711
            ++Y+ +ED+ ++F  P + DVKIG+ SY+P  SSEK   ++ KY   E +GFL+ G++V   H  +    ++++GR L + E   +G+  F        K      I  ++K+L+WF +QKQ+ F ASS+L  YE +S
Sbjct:  108 DVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTK-ETLKEGVSKFFHNGFCLRKDAIAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSS 244
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Ipmk (inositol polyphosphate multikinase [Source:MGI Symbol;Acc:MGI:1916968])

HSP 1 Score: 62.003 bits (149), Expect = 7.310e-11
Identity = 31/85 (36.47%), Postives = 52/85 (61.18%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRYHGRSLNQDEVYTKGI 561
            ++Y+ +ED+ ++F  P + DVKIG+ SY+P  SSEK   ++ KY   E +GFL+ G++V+    L  D Y      Q++ Y +G+
Sbjct:  108 DVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYH---LHSDSYE----TQNQHYGRGL 185
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Ipmk (inositol polyphosphate multikinase [Source:MGI Symbol;Acc:MGI:1916968])

HSP 1 Score: 62.003 bits (149), Expect = 7.310e-11
Identity = 31/85 (36.47%), Postives = 52/85 (61.18%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRYHGRSLNQDEVYTKGI 561
            ++Y+ +ED+ ++F  P + DVKIG+ SY+P  SSEK   ++ KY   E +GFL+ G++V+    L  D Y      Q++ Y +G+
Sbjct:  108 DVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYH---LHSDSYE----TQNQHYGRGL 185
[Close]
BLAST of Kinase vs. Ensembl Mouse
Match: Ip6k3 (inositol hexaphosphate kinase 3 [Source:MGI Symbol;Acc:MGI:3045325])

HSP 1 Score: 55.8398 bits (133), Expect = 2.935e-8
Identity = 46/179 (25.70%), Postives = 81/179 (45.25%), Query Frame = 1 
Query:  301 KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRES--VGFLITGIKVHEPTPLFF---DRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHV 822
            K + ++ +E+++ Q+K P + D+K+G   +    S EKK   ++K     S  +G  I G++V++     F   D+Y+GR L+  E + + +  FL         L    +  LQ LL     Q    F +SS+L+ Y+                  G   +G   ++V V++IDF H 
Sbjct:  189 KRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKARHMKKCAQSTSACLGVRICGMQVYQTDQKSFLCKDKYYGRKLSV-EGFRQALSQFLHDGTRLRAELLEPILRRLQALLTVIRSQSSYRFYSSSVLIIYDGEPPQTTQGST------SGGVTSG-DPAKVDVRMIDFAHT 359
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q8NFU5|IPMK_HUMAN (Inositol polyphosphate multikinase OS=Homo sapiens OX=9606 GN=IPMK PE=1 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 2.345e-20
Identity = 51/138 (36.96%), Postives = 82/138 (59.42%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIK---VHEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS 711
            +LY+ +ED+ ++F  P + DVKIG+ SY+P  SSEK   ++ KY   E +GFL+ G++   VH  +    ++++GRSL + E    G+  F    +   K      I  ++K+L+WF +QKQ+ F ASS+L  YE +S
Sbjct:  125 DLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTK-ETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQKQLNFYASSLLFVYEGSS 261
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q7TT16|IPMK_MOUSE (Inositol polyphosphate multikinase OS=Mus musculus OX=10090 GN=Ipmk PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 5.589e-19
Identity = 49/138 (35.51%), Postives = 81/138 (58.70%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKV---HEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS 711
            ++Y+ +ED+ ++F  P + DVKIG+ SY+P  SSEK   ++ KY   E +GFL+ G++V   H  +    ++++GR L + E   +G+  F        K      I  ++K+L+WF +QKQ+ F ASS+L  YE +S
Sbjct:  108 DVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASSEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTK-ETLKEGVSKFFHNGFCLRKDAIAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSS 244
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q99NI4|IPMK_RAT (Inositol polyphosphate multikinase OS=Rattus norvegicus OX=10116 GN=Ipmk PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 6.155e-19
Identity = 48/138 (34.78%), Postives = 81/138 (58.70%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKV---HEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESAS 711
            ++Y+ +ED+ ++F  P + DVKIG+ SY+P  S+EK   ++ KY   E +GFL+ G++V   H  +    ++++GR L + E   +G+  F        K      I  ++K+L+WF +QKQ+ F ASS+L  YE +S
Sbjct:  108 DVYLKLEDVTHKFNKPCIMDVKIGRKSYDPFASAEKIQQQVSKYPLMEEIGFLVLGMRVYHLHSDSYETQNQHYGRGLTK-ETLKEGVSKFFHNGFCLRKDAVAASIQKVEKILQWFENQKQLNFYASSLLFVYEGSS 244
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q8BWD2|IP6K3_MOUSE (Inositol hexakisphosphate kinase 3 OS=Mus musculus OX=10090 GN=Ip6k3 PE=2 SV=1)

HSP 1 Score: 55.8398 bits (133), Expect = 2.053e-7
Identity = 46/179 (25.70%), Postives = 81/179 (45.25%), Query Frame = 1 
Query:  301 KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRES--VGFLITGIKVHEPTPLFF---DRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHV 822
            K + ++ +E+++ Q+K P + D+K+G   +    S EKK   ++K     S  +G  I G++V++     F   D+Y+GR L+  E + + +  FL         L    +  LQ LL     Q    F +SS+L+ Y+                  G   +G   ++V V++IDF H 
Sbjct:  189 KRHRFLLLENVVSQYKQPCILDLKMGTRQHGDDASEEKKARHMKKCAQSTSACLGVRICGMQVYQTDQKSFLCKDKYYGRKLSV-EGFRQALSQFLHDGTRLRAELLEPILRRLQALLTVIRSQSSYRFYSSSVLIIYDGEPPQTTQGST------SGGVTSG-DPAKVDVRMIDFAHT 359
[Close]
BLAST of Kinase vs. UniProt/SwissProt
Match: sp|Q9LY23|IPMKA_ARATH (Inositol polyphosphate multikinase alpha OS=Arabidopsis thaliana OX=3702 GN=IPK2a PE=1 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 1.923e-6
Identity = 62/229 (27.07%), Postives = 99/229 (43.23%), Query Frame = 1 
Query:  271 HGIQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESV--GFLITGIKVHEPTPLFF---DRYHGRSLNQDEVYTKGIKMFLG----------PDHNRAKYL---ANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHVLP---ITEHDTNCIYALNSLIKYFHRV 894
            HG Q  +      + + +E+LL ++  PSV DVK+G  ++ P  S E     ++K     +V  GF I+G +V++     F   +R   R L+ D      ++ F+           PD   A  +   ++  +T L +L  WF +Q    F + SILM YE+ S           K  D        D+   VKL+DF HVL    + +H  N +  L S I +   +
Sbjct:   68 HGTQAVEGSDGAAMMV-LENLLAEYTKPSVMDVKMGSRTWYPDASEEYIQKCLKKDTGTTTVSSGFRISGFEVYDHKESSFWKPERKLLRGLDVDGARLT-LRKFVSSNSLSDTGSKPDSAFASSVYGGSHGILTQLLELKTWFENQTLYHFNSCSILMVYENES---------ILKGND-------DDARPQVKLVDFAHVLDGNGVIDH--NFLGGLCSFINFIREI 276
[Close]
BLAST of Kinase vs. TrEMBL
Match: G7YU38 (Kinase OS=Clonorchis sinensis OX=79923 GN=CLF_110952 PE=3 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 2.898e-39
Identity = 78/211 (36.97%), Postives = 120/211 (56.87%), Query Frame = 1 
Query:  295 YQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPT----PLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHVLPIT----EHDTNCIYALNSLIKYFHRVKTD 903
            +Q   LY+G+ D+L + K PS+ D+KIG+ +Y P  S++K   E  KYKW+  +GFLI+ I+V + +    P++ DR  GRSL+   VY  GI++FLGP+  R++ LA +F+T L +L EWF  Q ++ F ASS+L+AY+S     +           G +    +D  V+  LIDF    P+       D N +Y L +LI+ F R   +
Sbjct:   21 HQLSALYLGMSDVLEKLKHPSICDIKIGRNTYAPDASAKKIAIEKAKYKWQAELGFLISAIRVVDSSDDLRPVYIDRTFGRSLSPSTVYDHGIRVFLGPNMKRSRSLARRFVTQLTRLSEWFEQQDRLSFYASSLLLAYDSHQDGLHSEPTVISPSFPGADEEHDNDELVVTFLIDFARWRPLEPGAGSRDENFLYGLRNLIQLFQRASVE 231
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A4V6RGX2 (Kinase OS=Opisthorchis felineus OX=147828 GN=CRM22_006990 PE=3 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 3.569e-39
Identity = 82/209 (39.23%), Postives = 124/209 (59.33%), Query Frame = 1 
Query:  310 LYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPT----PLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYES-ASSXXXXXXXXXRKWCDGQEINGYHDSEVLVK--LIDFTHVLPIT----EHDTNCIYALNSLIKYFHRVKTD 903
            LY+G+ D+L + K PS+ D+KIG+ +Y P  S++K   E  KYKW+  +GFLI+ I+V + +    P++ DR  GRSL+   VY  GI++FLGP+  R++ LA +F+T L KL EWF  Q ++ F ASS+L+AY+S     ++     +  + D  E    HD++ LV   LIDF    P+       D N +Y L +LI+ F RV  +
Sbjct:   29 LYLGMSDVLEKLKHPSICDIKIGRNTYAPDASAKKIAIEKAKYKWQAELGFLISAIRVVDSSDDLRPVYIDRTFGRSLSPSTVYDHGIRVFLGPNMKRSRSLARRFVTQLNKLSEWFGQQDKLSFYASSLLLAYDSHQDGLHSEPTLTSSSFPDADE---EHDNDELVVTYLIDFARWRPLEPGAGSRDENFLYGLRNLIQLFQRVSAE 234
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A1S8WXA3 (Kinase (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_05050 PE=3 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 7.784e-39
Identity = 83/209 (39.71%), Postives = 124/209 (59.33%), Query Frame = 1 
Query:  310 LYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPT----PLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYES-ASSXXXXXXXXXRKWCDGQEINGYHDSEVLVK--LIDFTHVLPI----TEHDTNCIYALNSLIKYFHRVKTD 903
            LY+G+ D+L Q K PS+ D+KIG+ +Y P  S++K   E  KYKW+  +GFLI+ I+V + +    P++ DR  GRSL+   VY  GI++FLGP+  R++ LA +F+T L KL EWF  Q ++ F ASS+L+AY+S     ++     +  + D  E    HD++ LV   LIDF    P+       D N +Y L +LI+ F RV  +
Sbjct:  106 LYLGMSDVLEQLKHPSICDIKIGRNTYAPDASAKKIAVEKAKYKWQAELGFLISAIRVVDSSDDLRPVYIDRTFGRSLSPSTVYDHGIRVFLGPNMKRSRSLARRFVTQLNKLSEWFEQQDKLSFYASSLLLAYDSHQDDLHSEPTLTSSSFSDAGE---EHDNDELVVTYLIDFARWRPLESGAGSRDENFLYGLRNLIQLFQRVSAE 311
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A4S2LIB8 (Kinase OS=Opisthorchis felineus OX=147828 GN=CRM22_006990 PE=3 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 9.539e-39
Identity = 82/209 (39.23%), Postives = 124/209 (59.33%), Query Frame = 1 
Query:  310 LYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPT----PLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYES-ASSXXXXXXXXXRKWCDGQEINGYHDSEVLVK--LIDFTHVLPIT----EHDTNCIYALNSLIKYFHRVKTD 903
            LY+G+ D+L + K PS+ D+KIG+ +Y P  S++K   E  KYKW+  +GFLI+ I+V + +    P++ DR  GRSL+   VY  GI++FLGP+  R++ LA +F+T L KL EWF  Q ++ F ASS+L+AY+S     ++     +  + D  E    HD++ LV   LIDF    P+       D N +Y L +LI+ F RV  +
Sbjct:   59 LYLGMSDVLEKLKHPSICDIKIGRNTYAPDASAKKIAIEKAKYKWQAELGFLISAIRVVDSSDDLRPVYIDRTFGRSLSPSTVYDHGIRVFLGPNMKRSRSLARRFVTQLNKLSEWFGQQDKLSFYASSLLLAYDSHQDGLHSEPTLTSSSFPDADE---EHDNDELVVTYLIDFARWRPLEPGAGSRDENFLYGLRNLIQLFQRVSAE 264
[Close]
BLAST of Kinase vs. TrEMBL
Match: A0A095A5B3 (Kinase OS=Schistosoma haematobium OX=6185 GN=MS3_10661 PE=3 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 1.202e-38
Identity = 93/236 (39.41%), Postives = 124/236 (52.54%), Query Frame = 1 
Query:  298 QKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQEI---------------------------NGYHDSEVLVKLIDFTHVLPITE----HDTNCIYALNSLIKYFHRVKTD 903
            ++++LY+G++DLL  FK PS+ D+K+G+ +Y P  S  K   E  KYKWRE +GFL+TG+KV  P       FD + GRSLN   +Y  GI++FLGPD NRAK LANQF+  L +L +WF +Q    F ASS+L+AY+S   N     + N      Q                             N   D  VLV LIDFT    +T+     D N +Y LN LI+ F R   D
Sbjct:  108 EQKHLYLGLKDLLANFKHPSLCDLKMGRRTYAPDSSPSKIMIECAKYKWREEIGFLVTGLKVFYPDINEYTTFDIFFGRSLNPSTIYDNGIRLFLGPDVNRAKRLANQFVKKLTQLAKWFENQNCYHFYASSLLLAYDSVDVNDEIMSSPNTTTATTQLPYSYYHHDHDHHHSCQDNNKESIISNIDNNEADEYVLVYLIDFTRWELVTDCSQIKDENFLYGLNYLIELFQRASLD 343
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ipmkb (inositol polyphosphate multikinase [Source:NCBI gene;Acc:103035921])

HSP 1 Score: 95.1301 bits (235), Expect = 1.036e-21
Identity = 51/139 (36.69%), Postives = 80/139 (57.55%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRY---HGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASS 714
            +LY+ +ED+  +F+ P + DVKIG+ S++P  S EK+  +I KY   E +GFL+ G++V+  +   FD Y   +GR L +D +     K F   +  R   +    I  +QK+L+WF  Q Q+ F ASS+L  Y+  SS
Sbjct:  115 DLYLKLEDVTRRFQKPCIMDVKIGQRSFDPFASQEKREQQIRKYPLMEEIGFLVLGMRVYNVSLDSFDSYDQHYGRGLVKDTIKDGLSKFFFNGEVLRKDAITAS-IVKVQKILQWFEGQSQLNFYASSLLFVYDGVSS 252
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ipmka (inositol polyphosphate multikinase [Source:NCBI gene;Acc:103031896])

HSP 1 Score: 83.9593 bits (206), Expect = 8.572e-18
Identity = 46/136 (33.82%), Postives = 74/136 (54.41%), Query Frame = 1 
Query:  310 LYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESA 708
            +Y+ +ED   +F  P + DVKIG+ SY+P  S +K+  +I KY   E +GFL+ G++V+       +  D+ +GR L + E    G+  F        K + +  I  ++ +L WF  QKQ+ F ASS+L  YE +
Sbjct:  117 VYLKLEDATRRFARPCIMDVKIGRKSYDPYASQKKREEQIRKYPPMEEIGFLLLGMRVYHVNSESYISHDKLYGRGLRK-ETLKSGLAEFFHNGEELRKDVISLSICKIRDILHWFEGQKQLHFYASSLLFVYEGS 251
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ENSAMXT00000057629.1 (inositol hexakisphosphate kinase 2-like [Source:NCBI gene;Acc:103024783])

HSP 1 Score: 54.6842 bits (130), Expect = 6.114e-8
Identity = 33/147 (22.45%), Postives = 75/147 (51.02%), Query Frame = 1 
Query:  277 IQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKW--RESVGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYE 702
            ++ N K++ ++ +I +E+L +++++P V D+K+G   +    + EKK  +I K +     S+G  + G++V+       +F ++YHGR L+    + + +  F        + L    +  L+++       +   F +SS+L+ Y+
Sbjct:  175 MKENSKHRNQHKFILLENLTWRYRVPCVLDLKMGTRQHGDDATEEKKANQIRKCQQSTSSSIGVRLCGMQVYHSVTGQLMFMNKYHGRKLSLPG-FKEALCQFFSDGQVLRRELLTPVLQRLKEMRAVLESCESYRFFSSSLLIIYD 320
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ENSAMXT00000038029.1 (inositol hexakisphosphate kinase 2-like [Source:NCBI gene;Acc:103024783])

HSP 1 Score: 54.299 bits (129), Expect = 6.504e-8
Identity = 33/148 (22.30%), Postives = 75/148 (50.68%), Query Frame = 1 
Query:  277 IQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKW--RESVGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYES 705
            ++ N K++ ++ +I +E+L +++++P V D+K+G   +    + EKK  +I K +     S+G  + G++V+       +F ++YHGR L+    + + +  F        + L    +  L+++       +   F +SS+L+ Y+ 
Sbjct:  185 MKENSKHRNQHKFILLENLTWRYRVPCVLDLKMGTRQHGDDATEEKKANQIRKCQQSTSSSIGVRLCGMQVYHSVTGQLMFMNKYHGRKLSLPG-FKEALCQFFSDGQVLRRELLTPVLQRLKEMRAVLESCESYRFFSSSLLIIYDG 331
[Close]
BLAST of Kinase vs. Ensembl Cavefish
Match: ip6k2a (inositol hexakisphosphate kinase 2-like [Source:NCBI gene;Acc:103037522])

HSP 1 Score: 52.373 bits (124), Expect = 3.297e-7
Identity = 36/148 (24.32%), Postives = 75/148 (50.68%), Query Frame = 1 
Query:  277 IQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKW--RESVGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKY-LANQFITNLQKLLEWFNHQKQMGFIASSILMAYE 702
            ++ N K++ +  +I +E+L ++ ++P V D+K+G   +    S EKK  +I K +     S+G  + G++V++      +F ++YHGR L          + F   D  R ++ L +  +  L+++       +   F +SS+L+ Y+
Sbjct:  185 MKENAKHRNQYKFILLENLTWRHRVPCVLDLKMGTRQHGDDASEEKKAVQIRKCQQSTSASIGVRLCGMQVYQSDSGQLMFMNKYHGRKLTLSGFKEALFQFF--HDGRRLRHELLSPVLRRLREMQAALEACESYRFYSSSLLIIYD 330
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: ipmka (inositol polyphosphate multikinase a [Source:ZFIN;Acc:ZDB-GENE-090312-161])

HSP 1 Score: 90.1225 bits (222), Expect = 8.208e-21
Identity = 52/157 (33.12%), Postives = 82/157 (52.23%), Query Frame = 1 
Query:  241 LKEYTYQVGGHGIQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEP---TPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYE 702
            L+E   +  G  I  N       +Y+ +ED+  +F  P + DVK+G+ SY+P  S EK + E  KY   + +GFL+ G++V++P   T + +D++ GRSL  D +  +GI  F    H          I  L+ +  WF  Q+   F +SS+LM YE
Sbjct:   43 LREQVPRFMGTWIPPNSP---NTVYLKLEDVTCKFNKPCIMDVKMGRQSYDPCASQEKVDYERAKYPLMQEIGFLVLGMRVYQPETNTDVVYDKFFGRSLEPDNL-REGISKFFHNGHCLRLDALECVIQRLENIYTWFQQQRIWNFYSSSLLMVYE 195
[Close]
BLAST of Kinase vs. Ensembl Sea Lamprey
Match: IP6K2 (inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313])

HSP 1 Score: 49.6766 bits (117), Expect = 1.992e-7
Identity = 56/220 (25.45%), Postives = 93/220 (42.27%), Query Frame = 1 
Query:  313 YIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKK--NTEIEKYKWRESVGFLITGIKV-HEPTPLF--FDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQE----INGYHD-------SEVLVKLIDFTHVL-------PITEH--DTNCIYALNSLIKYFHRVK 897
            +I +E+L+  +  P + D+K+G   Y      +KK  +T   +      +G  I+G++V H  T  +   ++Y GR L+ +  + + +  F        K L    +  L +L      Q    F +SS+L+ YE                  GQE     NG+ D       ++V V++IDF H         P+     D NCI  L SLI++  +VK
Sbjct:    1 FILLENLVSTYLAPCILDLKMGVRQYGDDAPEDKKALHTRTCQQSTSSVLGVRISGMQVYHVDTRQYVHMNKYIGRKLSVNG-FKETLSQFFHNGQRLRKDLLEPVLRKLSELRVALERQDSYRFYSSSLLIIYE------------------GQEECRVGNGHGDGATSALTAKVDVRMIDFAHTTCRTFLDDPVAYDGPDENCIIGLRSLIRFLGQVK 201
[Close]
BLAST of Kinase vs. Ensembl Yeast
Match: ARG82 (Inositol polyphosphate multikinase (IPMK); sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes [Source:SGD;Acc:S000002580])

HSP 1 Score: 51.9878 bits (123), Expect = 4.341e-8
Identity = 44/162 (27.16%), Postives = 78/162 (48.15%), Query Frame = 1 
Query:  292 KYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNT--EIEKYKWRESVGFLITGIKVHE-PTPL-----------------FFDRYHGRSLNQDEVYTKGIKMFLGPDH---NRAKYLANQFITNLQKLLEWFNH--QKQMGFIASSILMAYE 702
            K +K   Y+ +E+LLY F  P++ D+K+GK  Y+   S EK+     + +     S+GF I G+K+ + P+ L                 F ++ +GRS   D+  +  I+++    H    R   L   F+  LQ    ++N   ++++  I+SS+L  YE
Sbjct:  107 KSEKSKQYLVLENLLYGFSKPNILDIKLGKTLYDSKASLEKRERMKRVSETTTSGSLGFRICGMKIQKNPSVLNQLSLEYYEEEADSDYIFINKLYGRS-RTDQNVSDAIELYFNNPHLSDARKHQLKKTFLKRLQL---FYNTMLEEEVRMISSSLLFIYE 264
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO31288 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYC7])

HSP 1 Score: 87.8113 bits (216), Expect = 5.971e-20
Identity = 55/192 (28.65%), Postives = 93/192 (48.44%), Query Frame = 1 
Query:  313 YIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPL---FFDRYHGRSLNQDEVYTKGIKMFL-GPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHVLPITEHDTNCIYALNSLI 876
            Y+ +ED+   F++P + DVKIGK+ ++P    +K   E+ K   +   G  I G KV  PT     +F    G++L  DE        FL G    R   + ++ +  ++ +L+W+  Q+     ASS+++ YE  +      + +++       I+  H  EV VK+IDF H    +E D N + AL  L+
Sbjct:  105 YLQLEDMTKGFRVPCILDVKIGKICWDPLAKEDKIKRELSKSALQRKYGLRILGFKVFNPTRQEYEYFSNADGKALITDEQLLNAFVYFLSGASGCRKTSVLSKILREMESILQWWEKQRTFLIRASSLMIIYEGENRTMAEERASDKG------IDLLH--EVKVKMIDFAHAFECSEKDDNFLEALKELM 288
[Close]
BLAST of Kinase vs. Ensembl Nematostella
Match: EDO40953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5S0])

HSP 1 Score: 46.2098 bits (108), Expect = 9.601e-6
Identity = 47/218 (21.56%), Postives = 93/218 (42.66%), Query Frame = 1 
Query:  313 YIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRES--VGFLITGIKVHEPTPLFF---DRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYE------------SASSXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHVL---PITEHDTNCIYALNSLIKYFHRVKTDH 906
            +I +E++ YQF  P + D+K+G   +     SEK+   + K +   S  +G    G++V++     F   ++Y+G  L + E + + +  FL         L    +  L++L +  + Q    F +SS+L+ YE            S         + +R        N  H ++V V++IDF H       +  D   ++ + +LI+    + + +
Sbjct:  155 FIVLENVAYQFSYPCILDLKMGTRQHGDDAPSEKRARIMAKVESSTSKTLGVRACGLQVYQQNSGRFMCRNKYYGLKLTE-EGFKRELVSFLNNGQRLRLELIEPLVQRLRRLYKVLDKQHSYRFYSSSLLLMYEGDEAIGHYERENSTHEKSEEENSLSRSNSTASFKNLRH-TKVDVRMIDFAHTTWGNTRSGPDKGYLFGIENLIRLLEEIMSSY 370
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BLAST of Kinase vs. Ensembl Medaka
Match: ipmkb (inositol polyphosphate multikinase [Source:NCBI gene;Acc:101168158])

HSP 1 Score: 87.8113 bits (216), Expect = 6.394e-19
Identity = 48/139 (34.53%), Postives = 80/139 (57.55%), Query Frame = 1 
Query:  307 NLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFF---DRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNL---QKLLEWFNHQKQMGFIASSILMAYES 705
            +LY+ +ED+   F  P + DVK+G+ SY+P  S +K+  +I+KY   E +GFLI G++V+      F   D+++GR L +D V   G+  F    HN A    +  + ++   +++L WF  Q+++ F ASS+L  YE 
Sbjct:  133 DLYLKLEDVTRHFVKPCIMDVKLGQQSYDPFASQDKREQQIKKYPLMEEIGFLILGMRVYNMCSDSFCSYDQHYGRGLVKDSV-KDGLARFF---HNGAGVRGDAVLASIWKVRQILHWFQSQRKLAFYASSLLFVYEG 267
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BLAST of Kinase vs. Ensembl Medaka
Match: ENSORLT00000001533.2 (inositol hexakisphosphate kinase 2 [Source:NCBI gene;Acc:101155919])

HSP 1 Score: 51.6026 bits (122), Expect = 5.664e-7
Identity = 38/162 (23.46%), Postives = 81/162 (50.00%), Query Frame = 1 
Query:  232 PQTLKEYTYQVGGHGIQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKW--RESVGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYE 702
            P +LK +  Q+    ++ N K++ +  +I +E+L +++ +P V D+K+G   +    S EKK  +I K +     S+G  + G++V++      +F ++YHGR L     + + +  F          L +  + +L+++       +   F +SS+L+ Y+
Sbjct:  169 PWSLKCHQQQL--QRMKENAKHRNQYKFILLENLTWRYTVPCVLDLKMGTRQHGDDASEEKKANQIRKCQQSTSASIGVRLCGMQVYQSDTGQLMFMNKYHGRKLAL-AGFKEALYQFFHNGRRLRHELLSPVLRSLREMQAALEACESYRFYSSSLLIIYD 327
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: ENSORLT00000001534.2 (inositol hexakisphosphate kinase 2 [Source:NCBI gene;Acc:101155919])

HSP 1 Score: 51.2174 bits (121), Expect = 7.137e-7
Identity = 38/162 (23.46%), Postives = 81/162 (50.00%), Query Frame = 1 
Query:  232 PQTLKEYTYQVGGHGIQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKW--RESVGFLITGIKVHEPTP---LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYE 702
            P +LK +  Q+    ++ N K++ +  +I +E+L +++ +P V D+K+G   +    S EKK  +I K +     S+G  + G++V++      +F ++YHGR L     + + +  F          L +  + +L+++       +   F +SS+L+ Y+
Sbjct:  180 PWSLKCHQQQL--QRMKENAKHRNQYKFILLENLTWRYTVPCVLDLKMGTRQHGDDASEEKKANQIRKCQQSTSASIGVRLCGMQVYQSDTGQLMFMNKYHGRKLAL-AGFKEALYQFFHNGRRLRHELLSPVLRSLREMQAALEACESYRFYSSSLLIIYD 338
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: ENSORLT00000021058.2 (inositol hexakisphosphate kinase 2 [Source:NCBI gene;Acc:101163245])

HSP 1 Score: 48.521 bits (114), Expect = 5.108e-6
Identity = 34/149 (22.82%), Postives = 75/149 (50.34%), Query Frame = 1 
Query:  277 IQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRES--VGFLITGIKV-HEPTP--LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESA 708
            +++N K++ +  +I +E+L ++  +P V D+K+G   +    + EKK  +I K +   S  +G    G++V H  T   ++ ++Y GR L     + + +  F        + L +  ++ L+++ +     +   F +SS+L+ Y+ A
Sbjct:  189 MKDNAKHRNQYKFILLENLTWRHAVPCVLDLKMGTRQHGDDATEEKKALQIRKCQQSTSALIGVRFCGMQVYHSDTDQLIYMNKYQGRKLTL-AGFKEALYQFFHSGRRLRQELLSPVLSRLREMKDALEACESYRFYSSSLLIIYDGA 336
[Close]
BLAST of Kinase vs. Ensembl Medaka
Match: ENSORLT00000030323.1 (inositol hexakisphosphate kinase 2 [Source:NCBI gene;Acc:101163245])

HSP 1 Score: 48.1358 bits (113), Expect = 6.452e-6
Identity = 34/149 (22.82%), Postives = 75/149 (50.34%), Query Frame = 1 
Query:  277 IQNNKKYQKENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRES--VGFLITGIKV-HEPTP--LFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESA 708
            +++N K++ +  +I +E+L ++  +P V D+K+G   +    + EKK  +I K +   S  +G    G++V H  T   ++ ++Y GR L     + + +  F        + L +  ++ L+++ +     +   F +SS+L+ Y+ A
Sbjct:  200 MKDNAKHRNQYKFILLENLTWRHAVPCVLDLKMGTRQHGDDATEEKKALQIRKCQQSTSALIGVRFCGMQVYHSDTDQLIYMNKYQGRKLTL-AGFKEALYQFFHSGRRLRQELLSPVLSRLREMKDALEACESYRFYSSSLLIIYDGA 347
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000022299.1 (SMESG000022299.1)

HSP 1 Score: 402.519 bits (1033), Expect = 1.738e-142
Identity = 203/204 (99.51%), Postives = 203/204 (99.51%), Query Frame = 1 
Query:  301 KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHVLPITEHDTNCIYALNSLIKYFHRVKTDHNY 912
            KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVS EKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSNYNYYKNNNRKWCDGQEINGYHDSEVLVKLIDFTHVLPITEHDTNCIYALNSLIKYFHRVKTDHNY
Sbjct:   41 KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSPEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSNYNYYKNNNRKWCDGQEINGYHDSEVLVKLIDFTHVLPITEHDTNCIYALNSLIKYFHRVKTDHNY 244
[Close]
BLAST of Kinase vs. Planmine SMEST
Match: SMESG000022299.1 (SMESG000022299.1)

HSP 1 Score: 402.134 bits (1032), Expect = 9.312e-142
Identity = 203/204 (99.51%), Postives = 203/204 (99.51%), Query Frame = 1 
Query:  301 KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSSEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSXXXXXXXXXRKWCDGQEINGYHDSEVLVKLIDFTHVLPITEHDTNCIYALNSLIKYFHRVKTDHNY 912
            KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVS EKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSNYNYYKNNNRKWCDGQEINGYHDSEVLVKLIDFTHVLPITEHDTNCIYALNSLIKYFHRVKTDHNY
Sbjct:   74 KENLYIGIEDLLYQFKLPSVADVKIGKVSYEPTVSPEKKNTEIEKYKWRESVGFLITGIKVHEPTPLFFDRYHGRSLNQDEVYTKGIKMFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASSNYNYYKNNNRKWCDGQEINGYHDSEVLVKLIDFTHVLPITEHDTNCIYALNSLIKYFHRVKTDHNY 277
The following BLAST results are available for this feature:
BLAST of Kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
IPMK4.882e-2136.96inositol polyphosphate multikinase [Source:HGNC Sy... [more]
IP6K38.531e-724.04inositol hexakisphosphate kinase 3 [Source:HGNC Sy... [more]
IP6K38.531e-724.04inositol hexakisphosphate kinase 3 [Source:HGNC Sy... [more]
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BLAST of Kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ipmk-14.140e-926.49Kinase [Source:UniProtKB/TrEMBL;Acc:O62519][more]
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BLAST of Kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Ipk26.158e-1928.44gene:FBgn0031267 transcript:FBtr0078074[more]
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BLAST of Kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ipmka3.468e-2227.43inositol polyphosphate multikinase a [Source:ZFIN;... [more]
ipmka7.244e-2226.99inositol polyphosphate multikinase a [Source:ZFIN;... [more]
ipmkb4.403e-2135.97inositol polyphosphate multikinase b [Source:ZFIN;... [more]
ip6k2a2.645e-824.49inositol hexakisphosphate kinase 2a [Source:ZFIN;A... [more]
ip6k2b6.067e-827.15inositol hexakisphosphate kinase 2b [Source:ZFIN;A... [more]
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BLAST of Kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
IPMK2.893e-1834.04inositol polyphosphate multikinase [Source:NCBI ge... [more]
sall11.493e-721.57spalt-like transcription factor 1 [Source:Xenbase;... [more]
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BLAST of Kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ipmk4.470e-2033.33inositol polyphosphate multikinase [Source:MGI Sym... [more]
Ipmk7.990e-2035.51inositol polyphosphate multikinase [Source:MGI Sym... [more]
Ipmk7.310e-1136.47inositol polyphosphate multikinase [Source:MGI Sym... [more]
Ipmk7.310e-1136.47inositol polyphosphate multikinase [Source:MGI Sym... [more]
Ip6k32.935e-825.70inositol hexaphosphate kinase 3 [Source:MGI Symbol... [more]
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BLAST of Kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8NFU5|IPMK_HUMAN2.345e-2036.96Inositol polyphosphate multikinase OS=Homo sapiens... [more]
sp|Q7TT16|IPMK_MOUSE5.589e-1935.51Inositol polyphosphate multikinase OS=Mus musculus... [more]
sp|Q99NI4|IPMK_RAT6.155e-1934.78Inositol polyphosphate multikinase OS=Rattus norve... [more]
sp|Q8BWD2|IP6K3_MOUSE2.053e-725.70Inositol hexakisphosphate kinase 3 OS=Mus musculus... [more]
sp|Q9LY23|IPMKA_ARATH1.923e-627.07Inositol polyphosphate multikinase alpha OS=Arabid... [more]
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BLAST of Kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G7YU382.898e-3936.97Kinase OS=Clonorchis sinensis OX=79923 GN=CLF_1109... [more]
A0A4V6RGX23.569e-3939.23Kinase OS=Opisthorchis felineus OX=147828 GN=CRM22... [more]
A0A1S8WXA37.784e-3939.71Kinase (Fragment) OS=Opisthorchis viverrini OX=619... [more]
A0A4S2LIB89.539e-3939.23Kinase OS=Opisthorchis felineus OX=147828 GN=CRM22... [more]
A0A095A5B31.202e-3839.41Kinase OS=Schistosoma haematobium OX=6185 GN=MS3_1... [more]
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BLAST of Kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ipmkb1.036e-2136.69inositol polyphosphate multikinase [Source:NCBI ge... [more]
ipmka8.572e-1833.82inositol polyphosphate multikinase [Source:NCBI ge... [more]
ENSAMXT00000057629.16.114e-822.45inositol hexakisphosphate kinase 2-like [Source:NC... [more]
ENSAMXT00000038029.16.504e-822.30inositol hexakisphosphate kinase 2-like [Source:NC... [more]
ip6k2a3.297e-724.32inositol hexakisphosphate kinase 2-like [Source:NC... [more]
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BLAST of Kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ipmka8.208e-2133.12inositol polyphosphate multikinase a [Source:ZFIN;... [more]
IP6K21.992e-725.45inositol hexakisphosphate kinase 2 [Source:HGNC Sy... [more]
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BLAST of Kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ARG824.341e-827.16Inositol polyphosphate multikinase (IPMK); sequent... [more]
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BLAST of Kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO312885.971e-2028.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO409539.601e-621.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ipmkb6.394e-1934.53inositol polyphosphate multikinase [Source:NCBI ge... [more]
ENSORLT00000001533.25.664e-723.46inositol hexakisphosphate kinase 2 [Source:NCBI ge... [more]
ENSORLT00000001534.27.137e-723.46inositol hexakisphosphate kinase 2 [Source:NCBI ge... [more]
ENSORLT00000021058.25.108e-622.82inositol hexakisphosphate kinase 2 [Source:NCBI ge... [more]
ENSORLT00000030323.16.452e-622.82inositol hexakisphosphate kinase 2 [Source:NCBI ge... [more]
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BLAST of Kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000022299.11.738e-14299.51SMESG000022299.1[more]
SMESG000022299.19.312e-14299.51SMESG000022299.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015577 ID=SMED30015577|Name=Kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=976bp
TGACTAATTAATACCGCTACTTTTGAAAACTTGAATGTGATTAATTCATT
TAATATTGTTTGCTGCACACTATTAGTAGTATAAATTAGTTATACTGTTT
CTTAAACGACATTTTATTTTTTATTAAAACCCTTTGTATTTCTTATTAAA
TATTTTACAATATAGAAATTTATAACAATTTTTTAGACGTCGAAAAGCCG
AGAACAATATGTTGAAGAATATCCTTCCATTCCCCAAACACTGAAGGAAT
ATACTTACCAAGTTGGAGGCCATGGTATTCAAAACAACAAAAAATATCAA
AAAGAAAATTTATACATTGGAATTGAAGATTTGCTCTATCAATTTAAACT
ACCATCAGTGGCAGATGTAAAAATTGGAAAAGTGAGTTACGAACCAACCG
TGTCATCCGAGAAAAAGAATACAGAAATAGAAAAATATAAATGGAGAGAA
TCAGTTGGATTTCTAATTACTGGAATTAAAGTACACGAGCCAACACCGCT
ATTCTTTGACAGATATCACGGCAGAAGTTTGAATCAGGATGAAGTTTATA
CAAAAGGAATTAAAATGTTTTTGGGTCCCGATCACAATCGGGCCAAATAT
CTTGCAAATCAATTCATCACTAACCTACAAAAGCTTCTCGAATGGTTCAA
TCATCAAAAGCAAATGGGATTCATAGCCTCATCAATTTTAATGGCCTATG
AAAGTGCCAGTAGTAACTATAATTATTATAAGAATAATAACAGAAAATGG
TGCGATGGACAAGAAATAAATGGATATCACGATTCAGAAGTGCTTGTAAA
ACTGATCGATTTCACTCATGTATTGCCGATAACAGAGCACGACACAAACT
GTATATATGCTCTCAATTCTTTGATCAAATATTTTCATCGCGTCAAAACG
GATCATAATTATTGATTTATTTGCAATTTGGTGGTTGTTTGTAAACTATT
CAAATCGGTAAAATGCCATTTAAATT
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protein sequence of SMED30015577-orf-1

>SMED30015577-orf-1 ID=SMED30015577-orf-1|Name=SMED30015577-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=117bp
MFLGPDHNRAKYLANQFITNLQKLLEWFNHQKQMGFIASSILMAYESASS
NYNYYKNNNRKWCDGQEINGYHDSEVLVKLIDFTHVLPITEHDTNCIYAL
NSLIKYFHRVKTDHNY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0032958inositol phosphate biosynthetic process
GO:0016310phosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0002056medial muscle cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR038286IPK_sf
IPR005522IPK
Vocabulary: molecular function
TermDefinition
GO:0008440inositol-1,4,5-trisphosphate 3-kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR038286Inositol polyphosphate kinase superfamilyGENE3DG3DSA:1.10.510.50coord: 3..116
e-value: 1.7E-19
score: 72.3
IPR005522Inositol polyphosphate kinasePFAMPF03770IPKcoord: 7..107
e-value: 3.4E-19
score: 69.5
IPR005522Inositol polyphosphate kinasePANTHERPTHR12400INOSITOL POLYPHOSPHATE KINASEcoord: 9..114
NoneNo IPR availablePANTHERPTHR12400:SF51INOSITOL POLYPHOSPHATE MULTIKINASEcoord: 9..114
NoneNo IPR availableSUPERFAMILYSSF56104SAICAR synthase-likecoord: 2..110