MRG-1

Overview


Name	MRG-1 (AFD29601.1)
Smed ID	SMED30015533
Length (bp)	1363

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of MRG-1 (SMED30015533) t-SNE clustered cells

Violin plots show distribution of expression levels for MRG-1 (SMED30015533) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of MRG-1 (SMED30015533) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for MRG-1 (SMED30015533) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30015533

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 11

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30015533	SMESG000022376.1	SmedASXL_006373	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30015533	SMESG000022376.1	SmedASXL_006373	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30015533	SMESG000022376.1	dd_Smed_v4_5890_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30015533	SMESG000022376.1	dd_Smed_v4_5890_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30015533	SMESG000022376.1	dd_Smed_v4_5890_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015533	SMESG000022376.1	dd_Smed_v4_5890_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30015533	SMESG000022376.1	dd_Smed_v4_5890_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30015533	SMESG000022376.1	dd_Smed_v4_5890_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30015533	SMESG000022376.1	dd_Smed_v4_5890_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30015533	SMESG000022376.1	SMED_31964_V2	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30015533	SMESG000022376.1	SMED_31964_V2	GPL14150	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of MRG-1 vs. Ensembl Human
Match: MORF4L1 (mortality factor 4 like 1 [Source:HGNC Symbol;Acc:HGNC:16989])

HSP 1 Score: 126.716 bits (317), Expect = 3.217e-33
Identity = 71/196 (36.22%), Postives = 109/196 (55.61%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV + +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +VD +L  Y ++ +  R    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS +YG+ +LLRL V I  +++YT  D  S+  L + +  F+++L  N    F   DY  A  +Y R+A+
Sbjct:   52 VDPTVENEETFMNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKS-RGNTDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYAEIL-ADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRKAV 235

[Close]

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV + +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +VD +L  Y ++ +  R    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS +YG+ +LLRL V I  +++YT  D  S+  L + +  F+++L  N    F   DY  A  +Y R+A+
Sbjct:   52 VDPTVENEETFMNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKS-RGNTDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYAEIL-ADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRKAV 235

[Close]

BLAST of MRG-1 vs. Ensembl Human
Match: MORF4L2 (mortality factor 4 like 2 [Source:HGNC Symbol;Acc:HGNC:16849])

HSP 1 Score: 126.331 bits (316), Expect = 4.796e-33
Identity = 66/181 (36.46%), Postives = 103/181 (56.91%), Query Frame = 3

Query:  804 NVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            N   +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS +YG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+A+Y R+A+
Sbjct:   66 NRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASAEYHRKAL 237

[Close]

BLAST of MRG-1 vs. Ensembl Human
Match: MORF4L2 (mortality factor 4 like 2 [Source:HGNC Symbol;Acc:HGNC:16849])

HSP 1 Score: 126.331 bits (316), Expect = 1.677e-32
Identity = 66/181 (36.46%), Postives = 103/181 (56.91%), Query Frame = 3

Query:  804 NVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            N   +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS +YG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+A+Y R+A+
Sbjct:  117 NRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASAEYHRKAL 288

[Close]

Query:  804 NVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            N   +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS +YG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+A+Y R+A+
Sbjct:  117 NRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASAEYHRKAL 288

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BLAST of MRG-1 vs. Ensembl Celegans
Match: mrg-1 (MRG (Mortality factor-Related Gene) related [Source:UniProtKB/TrEMBL;Acc:A7DTF0])

HSP 1 Score: 58.9214 bits (141), Expect = 2.645e-9
Identity = 54/209 (25.84%), Postives = 93/209 (44.50%), Query Frame = 3

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVE---------------GMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDM---------------SSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFK-LEDYITATADYTRRAMC 1349
            +K    + LR  L DD+DL+ R   ++ +P   SVD ++  Y      ++     NE     + D+  E+ E               G+  YFN ++G  LLYKFER QY ++V     +K +               S  YG ++ LR+L  +   +  T+ +   I+ +   +   I FL+ N  ++++   DY  A+ DY RR++ 
Sbjct:  126 MKVELPKPLRKILIDDYDLVCRYF-INIVPHEYSVDQIIEDY------IKTIPVSNEQMRTVD-DLLIEYEEADIKITNLALICTARGLVDYFNVTLGYQLLYKFERPQYNDLVKKRAMEKGIDITNPTALQDSGFRPSQEYGIVHFLRMLAKLPDYLKLTQWNDHVINRIMIGVHDLIVFLNKNHGKYYRGSSDYQGASNDYYRRSLA 326

[Close]

BLAST of MRG-1 vs. Ensembl Celegans
Match: mrg-1 (MRG (Mortality factor-Related Gene) related [Source:UniProtKB/TrEMBL;Acc:A7DTF0])

HSP 1 Score: 56.225 bits (134), Expect = 2.012e-8
Identity = 55/211 (26.07%), Postives = 94/211 (44.55%), Query Frame = 3

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVE---------------GMRKYFNTSIGS--LLLYKFERQQYFEVVNTNESKKDM---------------SSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFK-LEDYITATADYTRRAMC 1349
            +K    + LR  L DD+DL+ R   ++ +P   SVD ++  Y      ++     NE     + D+  E+ E               G+  YFN ++GS   LLYKFER QY ++V     +K +               S  YG ++ LR+L  +   +  T+ +   I+ +   +   I FL+ N  ++++   DY  A+ DY RR++ 
Sbjct:  126 MKVELPKPLRKILIDDYDLVCRYF-INIVPHEYSVDQIIEDY------IKTIPVSNEQMRTVD-DLLIEYEEADIKITNLALICTARGLVDYFNVTLGSSYQLLYKFERPQYNDLVKKRAMEKGIDITNPTALQDSGFRPSQEYGIVHFLRMLAKLPDYLKLTQWNDHVINRIMIGVHDLIVFLNKNHGKYYRGSSDYQGASNDYYRRSLA 328

[Close]

BLAST of MRG-1 vs. Ensembl Fly
Match: MRG15 (gene:FBgn0027378 transcript:FBtr0083125)

HSP 1 Score: 107.457 bits (267), Expect = 4.710e-25
Identity = 56/176 (31.82%), Postives = 96/176 (54.55%), Query Frame = 3

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRA 1343
            +K    + L+ +L DDW  + R+ +L  LP +++V  +  +Y +H + ++      E   N       + ++G+ +YFN  +GS LLYKFER QY +V+  +     +S +YGS +LLRL V +  ++SY+  D  S+  L   +Q F++FL  N   FF + ++I    +Y R A
Sbjct:  256 VKIKIPDELKHYLTDDWYAVVREHKLLELPAKVTVQQISEQYLAHKKSVKSTSASKEVAIN-------DVLDGIVEYFNVMLGSQLLYKFERTQYADVMQKHPDT-PLSELYGSFHLLRLFVRLGSMLSYSALDQQSMQNLLTHVQDFLKFLVKNSSIFFSMSNFINVDPEYVRNA 423

HSP 2 Score: 86.2705 bits (212), Expect = 5.790e-18
Identity = 31/63 (49.21%), Postives = 51/63 (80.95%), Query Frame = 3

Query:  120 GEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKEL 305
            GE++LC+HGPL+YEAK ++ + +++ + Y IHY GW+K WDEWV + R+LK+N+  +K+++EL
Sbjct:   25 GERVLCFHGPLIYEAKVLKTKPDATPVEYYIHYAGWSKNWDEWVPENRVLKYNDDNVKRRQEL 87

[Close]

BLAST of MRG-1 vs. Ensembl Fly
Match: MRG15 (gene:FBgn0027378 transcript:FBtr0333921)

HSP 1 Score: 107.457 bits (267), Expect = 4.864e-25
Identity = 56/176 (31.82%), Postives = 96/176 (54.55%), Query Frame = 3

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRA 1343
            +K    + L+ +L DDW  + R+ +L  LP +++V  +  +Y +H + ++      E   N       + ++G+ +YFN  +GS LLYKFER QY +V+  +     +S +YGS +LLRL V +  ++SY+  D  S+  L   +Q F++FL  N   FF + ++I    +Y R A
Sbjct:  261 VKIKIPDELKHYLTDDWYAVVREHKLLELPAKVTVQQISEQYLAHKKSVKSTSASKEVAIN-------DVLDGIVEYFNVMLGSQLLYKFERTQYADVMQKHPDT-PLSELYGSFHLLRLFVRLGSMLSYSALDQQSMQNLLTHVQDFLKFLVKNSSIFFSMSNFINVDPEYVRNA 428

HSP 2 Score: 86.2705 bits (212), Expect = 5.964e-18
Identity = 31/63 (49.21%), Postives = 51/63 (80.95%), Query Frame = 3

Query:  120 GEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKEL 305
            GE++LC+HGPL+YEAK ++ + +++ + Y IHY GW+K WDEWV + R+LK+N+  +K+++EL
Sbjct:   25 GERVLCFHGPLIYEAKVLKTKPDATPVEYYIHYAGWSKNWDEWVPENRVLKYNDDNVKRRQEL 87

[Close]

BLAST of MRG-1 vs. Ensembl Zebrafish
Match: morf4l1 (mortality factor 4 like 1 [Source:ZFIN;Acc:ZDB-GENE-040718-348])

HSP 1 Score: 132.88 bits (333), Expect = 7.372e-35
Identity = 76/196 (38.78%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +VD VL  Y ++ +  R    + E   N       E V G+R+YFN  +G+ LLYKFER QY E++  N     MS IYG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  134 VDPTVESEETFINRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKNVDAVLEDYANYKKS-RGNSDNKEYAVN-------EVVAGIREYFNVMLGTQLLYKFERPQYAEIL-ANHPDTSMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLSYLQDFLKYLVKNSSSLFSASDYEVAPPEYHRKAV 317

HSP 2 Score: 70.0922 bits (170), Expect = 7.487e-13
Identity = 31/77 (40.26%), Postives = 49/77 (63.64%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D KPK+  G+         +   +C++I  +  +++Y IHY GWNK WDEWV ++R+LK+ ++ ++KQKELQ
Sbjct:    1 MAPKQDPKPKFQEGKMRF------VSSTRCVKINIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDSNLQKQKELQ 71

[Close]

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +VD VL  Y ++ +  R    + E   N       E V G+R+YFN  +G+ LLYKFER QY E++  N     MS IYG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  134 VDPTVESEETFINRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKNVDAVLEDYANYKKS-RGNSDNKEYAVN-------EVVAGIREYFNVMLGTQLLYKFERPQYAEIL-ANHPDTSMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLSYLQDFLKYLVKNSSSLFSASDYEVAPPEYHRKAV 317

HSP 2 Score: 70.0922 bits (170), Expect = 7.487e-13
Identity = 31/77 (40.26%), Postives = 49/77 (63.64%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D KPK+  G+         +   +C++I  +  +++Y IHY GWNK WDEWV ++R+LK+ ++ ++KQKELQ
Sbjct:    1 MAPKQDPKPKFQEGKMRF------VSSTRCVKINIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDSNLQKQKELQ 71

[Close]

BLAST of MRG-1 vs. Ensembl Zebrafish
Match: morf4l1 (mortality factor 4 like 1 [Source:ZFIN;Acc:ZDB-GENE-040718-348])

HSP 1 Score: 132.88 bits (333), Expect = 1.082e-34
Identity = 76/196 (38.78%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +VD VL  Y ++ +  R    + E   N       E V G+R+YFN  +G+ LLYKFER QY E++  N     MS IYG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  140 VDPTVESEETFINRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKNVDAVLEDYANYKKS-RGNSDNKEYAVN-------EVVAGIREYFNVMLGTQLLYKFERPQYAEIL-ANHPDTSMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLSYLQDFLKYLVKNSSSLFSASDYEVAPPEYHRKAV 323

HSP 2 Score: 108.227 bits (269), Expect = 7.314e-26
Identity = 43/77 (55.84%), Postives = 61/77 (79.22%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D KPK+  GE++LC+HGPLLYEAKC++I  +  +++Y IHY GWNK WDEWV ++R+LK+ ++ ++KQKELQ
Sbjct:    1 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKINIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDSNLQKQKELQ 77

[Close]

BLAST of MRG-1 vs. Ensembl Xenopus
Match: cog3 (component of oligomeric golgi complex 3 [Source:Xenbase;Acc:XB-GENE-855843])

HSP 1 Score: 125.946 bits (315), Expect = 1.534e-32
Identity = 71/196 (36.22%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +V+ VL  Y ++ +  R    + E   N       E V G+++YFN  +G+ LLYKFER QY +++  +     MS +YG+ +LLRL V I  ++SYT  D  S+  L + +  F+++L  N    F   DY  A  +Y R+A+
Sbjct:   96 IDPTVESEETFMNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFNLPAKKNVETVLEEYATYKKS-RGNTDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYADIL-ADHPDAPMSQVYGAPHLLRLFVRIGAMLSYTPLDEKSLALLLNYLHDFLKYLAKNSSLLFSASDYEVAPPEYHRKAV 279

HSP 2 Score: 51.9878 bits (123), Expect = 7.303e-7
Identity = 19/33 (57.58%), Postives = 27/33 (81.82%), Query Frame = 3

Query:  210 HYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            H+ GWNK WDEWV ++R+LK+ +  ++KQKELQ
Sbjct:    1 HWLGWNKNWDEWVPESRVLKYVDTNLQKQKELQ 33

[Close]

BLAST of MRG-1 vs. Ensembl Xenopus
Match: cog3 (component of oligomeric golgi complex 3 [Source:Xenbase;Acc:XB-GENE-855843])

HSP 1 Score: 125.561 bits (314), Expect = 4.578e-32
Identity = 71/196 (36.22%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +V+ VL  Y ++ +  R    + E   N       E V G+++YFN  +G+ LLYKFER QY +++  +     MS +YG+ +LLRL V I  ++SYT  D  S+  L + +  F+++L  N    F   DY  A  +Y R+A+
Sbjct:  122 IDPTVESEETFMNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFNLPAKKNVETVLEEYATYKKS-RGNTDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYADIL-ADHPDAPMSQVYGAPHLLRLFVRIGAMLSYTPLDEKSLALLLNYLHDFLKYLAKNSSLLFSASDYEVAPPEYHRKAV 305

HSP 2 Score: 64.3142 bits (155), Expect = 7.707e-11
Identity = 23/51 (45.10%), Postives = 39/51 (76.47%), Query Frame = 3

Query:  159 EAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            ++ C+++  +  +++Y IHY GWNK WDEWV ++R+LK+ +  ++KQKELQ
Sbjct:    9 KSHCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKELQ 59

[Close]

BLAST of MRG-1 vs. Ensembl Xenopus
Match: cog3 (component of oligomeric golgi complex 3 [Source:Xenbase;Acc:XB-GENE-855843])

HSP 1 Score: 125.176 bits (313), Expect = 7.509e-32
Identity = 71/196 (36.22%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +V+ VL  Y ++ +  R    + E   N       E V G+++YFN  +G+ LLYKFER QY +++  +     MS +YG+ +LLRL V I  ++SYT  D  S+  L + +  F+++L  N    F   DY  A  +Y R+A+
Sbjct:  140 IDPTVESEETFMNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFNLPAKKNVETVLEEYATYKKS-RGNTDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYADIL-ADHPDAPMSQVYGAPHLLRLFVRIGAMLSYTPLDEKSLALLLNYLHDFLKYLAKNSSLLFSASDYEVAPPEYHRKAV 323

HSP 2 Score: 105.916 bits (263), Expect = 6.032e-25
Identity = 41/77 (53.25%), Postives = 60/77 (77.92%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D +PK+  GE++LC+HGPLLYEAKC+++  +  +++Y IHY GWNK WDEWV ++R+LK+ +  ++KQKELQ
Sbjct:    1 MAPKQDPRPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKELQ 77

[Close]

BLAST of MRG-1 vs. Ensembl Xenopus
Match: cog3 (component of oligomeric golgi complex 3 [Source:Xenbase;Acc:XB-GENE-855843])

HSP 1 Score: 124.79 bits (312), Expect = 1.578e-31
Identity = 71/196 (36.22%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +V+ VL  Y ++ +  R    + E   N       E V G+++YFN  +G+ LLYKFER QY +++  +     MS +YG+ +LLRL V I  ++SYT  D  S+  L + +  F+++L  N    F   DY  A  +Y R+A+
Sbjct:  149 IDPTVESEETFMNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFNLPAKKNVETVLEEYATYKKS-RGNTDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYADIL-ADHPDAPMSQVYGAPHLLRLFVRIGAMLSYTPLDEKSLALLLNYLHDFLKYLAKNSSLLFSASDYEVAPPEYHRKAV 332

HSP 2 Score: 65.4698 bits (158), Expect = 3.813e-11
Identity = 25/54 (46.30%), Postives = 40/54 (74.07%), Query Frame = 3

Query:  150 LLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            +L  A C+++  +  +++Y IHY GWNK WDEWV ++R+LK+ +  ++KQKELQ
Sbjct:   33 ILLIAHCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKELQ 86

[Close]

BLAST of MRG-1 vs. Ensembl Xenopus
Match: cog3 (component of oligomeric golgi complex 3 [Source:Xenbase;Acc:XB-GENE-855843])

HSP 1 Score: 124.79 bits (312), Expect = 1.593e-31
Identity = 71/196 (36.22%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +V+ VL  Y ++ +  R    + E   N       E V G+++YFN  +G+ LLYKFER QY +++  +     MS +YG+ +LLRL V I  ++SYT  D  S+  L + +  F+++L  N    F   DY  A  +Y R+A+
Sbjct:  150 IDPTVESEETFMNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFNLPAKKNVETVLEEYATYKKS-RGNTDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYADIL-ADHPDAPMSQVYGAPHLLRLFVRIGAMLSYTPLDEKSLALLLNYLHDFLKYLAKNSSLLFSASDYEVAPPEYHRKAV 333

HSP 2 Score: 94.3597 bits (233), Expect = 7.927e-21
Identity = 35/63 (55.56%), Postives = 52/63 (82.54%), Query Frame = 3

Query:  123 EKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            E++LC+HGPLLYEAKC+++  +  +++Y IHY GWNK WDEWV ++R+LK+ +  ++KQKELQ
Sbjct:   25 ERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKELQ 87

[Close]

BLAST of MRG-1 vs. Ensembl Mouse
Match: Morf4l2 (mortality factor 4 like 2 [Source:MGI Symbol;Acc:MGI:1927167])

HSP 1 Score: 128.642 bits (322), Expect = 1.962e-33
Identity = 67/177 (37.85%), Postives = 102/177 (57.63%), Query Frame = 3

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS IYG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+ADY R+A+
Sbjct:  121 VKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL 288

[Close]

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS IYG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+ADY R+A+
Sbjct:  121 VKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL 288

[Close]

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS IYG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+ADY R+A+
Sbjct:  121 VKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL 288

[Close]

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS IYG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+ADY R+A+
Sbjct:  121 VKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL 288

[Close]

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS IYG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+ADY R+A+
Sbjct:  121 VKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL 288

[Close]

BLAST of MRG-1 vs. UniProt/SwissProt
Match: sp|Q9R0Q4|MO4L2_MOUSE (Mortality factor 4-like protein 2 OS=Mus musculus OX=10090 GN=Morf4l2 PE=1 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 1.372e-32
Identity = 67/177 (37.85%), Postives = 102/177 (57.63%), Query Frame = 3

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS IYG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+ADY R+A+
Sbjct:  121 VKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL 288

[Close]

BLAST of MRG-1 vs. UniProt/SwissProt
Match: sp|Q6QI89|MO4L2_RAT (Mortality factor 4-like protein 2 OS=Rattus norvegicus OX=10116 GN=Morf4l2 PE=2 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 1.444e-32
Identity = 67/177 (37.85%), Postives = 102/177 (57.63%), Query Frame = 3

Query:  816 LKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS IYG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+ADY R+A+
Sbjct:  121 VKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVGGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASADYHRKAL 288

[Close]

BLAST of MRG-1 vs. UniProt/SwissProt
Match: sp|Q4R578|MO4L2_MACFA (Mortality factor 4-like protein 2 OS=Macaca fascicularis OX=9541 GN=MORF4L2 PE=2 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 7.735e-32
Identity = 66/181 (36.46%), Postives = 103/181 (56.91%), Query Frame = 3

Query:  804 NVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            N   +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS +YG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+A+Y R+A+
Sbjct:  117 NRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASAEYHRKAL 288

[Close]

BLAST of MRG-1 vs. UniProt/SwissProt
Match: sp|Q5R905|MO4L2_PONAB (Mortality factor 4-like protein 2 OS=Pongo abelii OX=9601 GN=MORF4L2 PE=2 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 8.056e-32
Identity = 66/181 (36.46%), Postives = 103/181 (56.91%), Query Frame = 3

Query:  804 NVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            N   +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS +YG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+A+Y R+A+
Sbjct:  117 NRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASAEYHRKAL 288

[Close]

BLAST of MRG-1 vs. UniProt/SwissProt
Match: sp|A5A6J5|MO4L2_PANTR (Mortality factor 4-like protein 2 OS=Pan troglodytes OX=9598 GN=MORF4L2 PE=2 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 8.056e-32
Identity = 66/181 (36.46%), Postives = 103/181 (56.91%), Query Frame = 3

Query:  804 NVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            N   +K    E L+ WL +DWDL+TRQ +L +LP + +VD +L  Y ++C+  +    + E   N       E V G+++YFN  +G+ LLYKFER QY E++  +     MS +YG+ +LLRL V I  +++YT  D  S+  L   +  F+++L  N    F   DY  A+A+Y R+A+
Sbjct:  117 NRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEY-ANCKKSQGNVDNKEYAVN-------EVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDA-PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASAEYHRKAL 288

[Close]

BLAST of MRG-1 vs. TrEMBL
Match: H9CXT0 (MRG-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 738.028 bits (1904), Expect = 0.000e+0
Identity = 423/423 (100.00%), Postives = 423/423 (100.00%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYXXXXXXXXXXXXXXXXXRKSSRSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTDAGTSVVSEELLXXXXXXXXXXXXXXXXXXXXXXXXNSEISVDKSLVTEEKSTIEDISLTNNEAXXXXXXXXXXXXXXXRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAMC 1349
            MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYKESRKKKDNRKKMINEKRKSSRSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTDAGTSVVSEELLDDQKSSIKDKSVSSKTRTRKRRLSNSEISVDKSLVTEEKSTIEDISLTNNEATNSNKSTNSSKSKKSRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAMC
Sbjct:    1 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYKESRKKKDNRKKMINEKRKSSRSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTDAGTSVVSEELLDDQKSSIKDKSVSSKTRTRKRRLSNSEISVDKSLVTEEKSTIEDISLTNNEATNSNKSTNSSKSKKSRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAMC 423

[Close]

BLAST of MRG-1 vs. TrEMBL
Match: A0A0A1XPQ2 (NuA4 complex subunit EAF3 homolog OS=Zeugodacus cucurbitae OX=28588 GN=MRG15 PE=4 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 3.567e-48
Identity = 120/414 (28.99%), Postives = 211/414 (50.97%), Query Frame = 3

Query:  108 KYSIGEKLLCYHGPLLYEAKCIE--IQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYXXXXXXXXXXXXXXXXXRKSSRSSQDKIRFMGSASETS-NRSFGESEDGKASKITTED-ENLENKTDAGTSVVSEELLXXXXXXXXXXXXXXXXXXXXXXXXNSEISVDKSLVTEEKSTIEDISLTNNEAXXXXXXXXXXXXXXXRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTR 1337
            K++ GEK+LC+HGPL+YEAK ++  I +  +I+Y IHY GWNK WDEWV + R+LK+NEA +++QKE+   +  +  K         +   +  +S+D     G+AS +S +R+   S+D   + +         N++   TS    +  D           +       +     +     +    +KS    +  +NN  T ++ ST++  S ++RL   D  V + +T+++ + V   K    + L+  LADDWD ITRQ +L  +P +++V D++ +Y +  +  +      E   N       + + G+ +YFN  IGS LLYKFER QY E++     +  +S +YG  +LLRL V +  ++ ++  D  S+  L   +  F++FL  N   +F + +++  + +Y R
Sbjct:    6 KFAEGEKVLCFHGPLIYEAKALKSTITKDKQIKYYIHYAGWNKNWDEWVPENRVLKYNEANVQRQKEVFKQHSNAAGKNKKSTPKGKKGEGAGATSKD-----GTASGSSESRASTPSKDLNTTPLAAPSTSGRGNRSKPTTSTPVAKDSDGSAKEDTTAPSAGNKDETTKEEPPKKKRGGSTSNASDKSNGSGVGTSNNPITPASTSTSTGNSLQNRL---DTCVENEETFLSKVEV---KIKIPDELKQCLADDWDAITRQHKLLDIPAKITVQDIVDQYIAFKKTSKSTNASKEVAIN-------DVLNGVVEYFNVMIGSQLLYKFERPQYAEILQ-QHPETPLSKLYGGFHLLRLFVKLGSMLGFSALDEKSMQMLLVHLHDFLKFLVKNSATYFSMTNFVNVSPEYHR 400

[Close]

BLAST of MRG-1 vs. TrEMBL
Match: A0A087ZV33 (MRG domain-containing protein OS=Apis mellifera OX=7460 GN=LOC413181 PE=4 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 4.540e-47
Identity = 132/425 (31.06%), Postives = 208/425 (48.94%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIE--IQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYXXXXXXXXXXXXXXXXXRKSSRSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTD--AGTSVVSEELLXXXXXXXXXXXXXXXXXXXXXXXXNSEISVDKSLVTEEKSTIEDISLTNNEAXXXXXXXXXXXXXXXRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKL-EDYITATADYTRR 1340
            MP K     K+  GEK+LC+HGPL+YEAKC++  I +  +I+Y IHY GWNK WDEWV ++R+LK+NEA +++Q+E+Q  +                   S++ S  K +   ++S+T  R    SE G+           E  TD  A T V                                  +VDK +    KST  +++ +++     + ++++ + K+SRL P  ET    + Y+T + V   K    E L+  L D+ ++I +  +L  LP + +VD +L  Y          E  + G  +  R+   E  +G+R+YFN S+G  LLYK+ER Q+ +++N N      S +YG+ +LLRL V +  ++SYT  D  SI  L      F+ +L  N  E F L +DY  +  DY R+
Sbjct:    1 MPPKC----KFQEGEKVLCFHGPLIYEAKCLKSSITKEKQIKYFIHYAGWNKNWDEWVPESRVLKYNEANVQRQREVQRAH-------------------SNQQSAQKNKKGSTSSKTQGR---RSEGGR-----------EKDTDSRASTPVA---------------------------------TVDKGVSRFNKSTSSNVTPSSSH----DSTSDAPRKKRSRLEPTGET----EEYLTKVEV---KIKIPEELKYVLIDESEVILKHHKLPALPVKNTVDKILDDY---------VESKSIGKNDSVRESTLEITKGIREYFNISLGLQLLYKWERPQFIQIMNDNPETLP-SQLYGAFHLLRLFVRLGGMLSYTTLDERSIQLLLSHFHDFLLYLQKNNTELFNLQQDYADSPPDYHRK 334

[Close]

BLAST of MRG-1 vs. TrEMBL
Match: A0A1I8MAE3 (MRG domain-containing protein OS=Musca domestica OX=7370 GN=101900840 PE=4 SV=1)

HSP 1 Score: 176.792 bits (447), Expect = 7.108e-47
Identity = 122/427 (28.57%), Postives = 208/427 (48.71%), Query Frame = 3

Query:  108 KYSIGEKLLCYHGPLLYEAKCIE--IQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYXXXXXXXXXXXXXXXXXRKSSRSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTDAGTSVVSEELLXXXXXXXXXXXXXXXXXXXXXXXXNSEISVDK-----SLVTEEKSTIEDISLTNNEAXXXXXXXXXXXX---------XXXRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRR 1340
            K++ GEK+LC+HGPL+YEAK ++  + +  +++Y +HY GWNK WDEWV + R+LK+NE  +++QK+LQ  +                 ++ +R +  K +   +    S  S   S  G  S+ +T  + L   T A T+  S      ++ S   +S    +        + +  V K     S  + EKST    +++N  A+    ++ S  +              V LD  V   +T+++ I V   K    + L+  LADDWD ITRQ +L  +P +++V D++ +Y S  +  +      E           + + G+ +YFN  +GS LLYKFER QY +++   +    +S +YGS +LLRL V +  ++ Y+  D  S+  L   +  F+++L  N   FF +  ++  T +Y R 
Sbjct:    6 KFAEGEKVLCFHGPLIYEAKALKSTVTKDKQLKYFVHYAGWNKNWDEWVPEHRVLKYNETNLQRQKDLQKEHDAK--------------KEKNRKNTAKGKKGETVGANSKESGATSSGGSESRASTPSKELN--TSASTNASSGRANRSKQISSATESKKDGSGREDSSKDDKDEPVVKKKRGASTSSSEKSTANTTAVSNASASGPGATSASPATLSNNNISNTTSQTNVRLDPCVESEETFLSKIEV---KIKIPDELKQCLADDWDAITRQHKLLDIPAKITVQDIVDQYISFKKSAKSTNAGKELAIT-------DVLNGVVEYFNVMLGSQLLYKFERPQYADILQQYQDI-PLSKLYGSFHLLRLFVKLGSMLGYSDLDEKSMQLLLVHLHDFLKYLVKNSATFFSMSSFVNVTPEYHRH 405

[Close]

BLAST of MRG-1 vs. TrEMBL
Match: A0A0K8VCW1 (NuA4 complex subunit EAF3 OS=Bactrocera latifrons OX=174628 GN=MRG15 PE=4 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 2.636e-46
Identity = 123/432 (28.47%), Postives = 213/432 (49.31%), Query Frame = 3

Query:  108 KYSIGEKLLCYHGPLLYEAKCIE--IQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYXXXXXXXXXXXXXXXXXRKSSRSSQDKIRFMGSASETS-NRSFGESED--------------GKASKITT-----EDENLENKTDAGTSVVSEELLXXXXXXXXXXXXXXXXXXXXXXXXNSEISVDKSLVTEEKSTIEDISLTNNEAXXXXXXXXXXXXXXXRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTR 1337
            K++ GEK+LC+HGPL+YEAK ++  I +  +I+Y IHY GWNK WDEWV + R+LK+NEA +++QKE+   +  +  K         +   +  +S+D     G+AS +S +R+   S+D              G  SK TT     +D ++  K D+  +  +++  +  K     K     T     + + S      + +T   +T   I    +               ++RL   D  V + +T+++ + V   K    + L+  LADDWD ITRQ +L  +P +++V D++ +Y +  +  +      E   N       + + G+ +YFN  IGS LLYKFER QY E++     +  +S +YG  +LLRL V +  ++ ++  D  S+  L   +  F++FL  N   +F + +++  + +Y R
Sbjct:    6 KFAEGEKVLCFHGPLIYEAKALKSTITKDKQIKYYIHYAGWNKNWDEWVPENRVLKYNEANVQRQKEVYKQHSNAAGKNKKSTPKGKKSEGAGATSKD-----GTASGSSESRASTPSKDLNTTPLAAPSTSGRGNRSKPTTSTPIAKDSDVSAKDDSTAATSNKD--ETTKDEPPKKKRGGSTSNASDKSNGSGAGTSSNTITTPAATGTSIGSAGSS-------------HQNRL---DTCVENEETFLSKVEV---KIKIPDELKQCLADDWDAITRQHKLLDIPAKITVQDIVDQYIAFKKTSKSTNASKEVAIN-------DVLNGVVEYFNVMIGSQLLYKFERPQYAEILQ-QHPETPLSKLYGGFHLLRLFVKLGSMLGFSALDEKSMQMLLVHLHDFLKFLVKNSATYFSMTNFVNVSPEYHR 403

[Close]

BLAST of MRG-1 vs. Ensembl Cavefish
Match: morf4l1 (mortality factor 4 like 1 [Source:NCBI gene;Acc:103024642])

HSP 1 Score: 131.724 bits (330), Expect = 1.108e-34
Identity = 76/196 (38.78%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +VD VL  Y ++ +  R    + E   N       E V G+R+YFN  +G+ LLYKFER QY E++  N     MS IYG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  113 VDPTVESEETFINRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKNVDAVLEDYANYKKS-RGTSDNKEYAVN-------EVVAGIREYFNVMLGTQLLYKFERPQYAEIL-ANHPDTSMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLSYLQDFLKYLVKNSSSLFNASDYEVAPPEYHRKAV 296

HSP 2 Score: 107.842 bits (268), Expect = 6.183e-26
Identity = 43/77 (55.84%), Postives = 61/77 (79.22%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D KPK+  GE++LC+HGPLLYEAKC++I  +  +++Y IHY GWNK WDEWV ++R+LK+ ++ ++KQKELQ
Sbjct:    1 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKINIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDSNLQKQKELQ 77

[Close]

BLAST of MRG-1 vs. Ensembl Cavefish
Match: morf4l1 (mortality factor 4 like 1 [Source:NCBI gene;Acc:103024642])

HSP 1 Score: 132.494 bits (332), Expect = 1.232e-34
Identity = 76/196 (38.78%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +VD VL  Y ++ +  R    + E   N       E V G+R+YFN  +G+ LLYKFER QY E++  N     MS IYG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  140 VDPTVESEETFINRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKNVDAVLEDYANYKKS-RGTSDNKEYAVN-------EVVAGIREYFNVMLGTQLLYKFERPQYAEIL-ANHPDTSMSQIYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLSYLQDFLKYLVKNSSSLFNASDYEVAPPEYHRKAV 323

HSP 2 Score: 108.227 bits (269), Expect = 7.043e-26
Identity = 43/77 (55.84%), Postives = 61/77 (79.22%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D KPK+  GE++LC+HGPLLYEAKC++I  +  +++Y IHY GWNK WDEWV ++R+LK+ ++ ++KQKELQ
Sbjct:    1 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKINIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDSNLQKQKELQ 77

[Close]

BLAST of MRG-1 vs. Ensembl Cavefish
Match: MSL3 (MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7370])

HSP 1 Score: 55.4546 bits (132), Expect = 7.810e-8
Identity = 28/81 (34.57%), Postives = 48/81 (59.26%), Query Frame = 3

Query:   99 IKPKYSIGEKLLCYH-----GPLLYEAKCIEI------QESSEI-RYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKEL 305
            +K K+  GEK+LC+        +LY+AK ++I      + S  + +YLIH+ GWN++WD W  +  +L+ +E   K Q++L
Sbjct:    6 MKFKFRKGEKVLCFEPDPSKAKVLYDAKVVDIVVGKDEKGSRRVPKYLIHFNGWNRSWDRWAAEDHVLRDSEENRKLQRKL 86

[Close]

BLAST of MRG-1 vs. Ensembl Cavefish
Match: MSL3 (MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7370])

HSP 1 Score: 55.0694 bits (131), Expect = 9.889e-8
Identity = 28/81 (34.57%), Postives = 48/81 (59.26%), Query Frame = 3

Query:   99 IKPKYSIGEKLLCYH-----GPLLYEAKCIEI------QESSEI-RYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKEL 305
            +K K+  GEK+LC+        +LY+AK ++I      + S  + +YLIH+ GWN++WD W  +  +L+ +E   K Q++L
Sbjct:    6 MKFKFRKGEKVLCFEPDPSKAKVLYDAKVVDIVVGKDEKGSRRVPKYLIHFNGWNRSWDRWAAEDHVLRDSEENRKLQRKL 86

[Close]

BLAST of MRG-1 vs. Ensembl Cavefish
Match: MSL3 (MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7370])

HSP 1 Score: 55.0694 bits (131), Expect = 1.086e-7
Identity = 28/81 (34.57%), Postives = 48/81 (59.26%), Query Frame = 3

Query:   99 IKPKYSIGEKLLCYH-----GPLLYEAKCIEI------QESSEI-RYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKEL 305
            +K K+  GEK+LC+        +LY+AK ++I      + S  + +YLIH+ GWN++WD W  +  +L+ +E   K Q++L
Sbjct:    6 MKFKFRKGEKVLCFEPDPSKAKVLYDAKVVDIVVGKDEKGSRRVPKYLIHFNGWNRSWDRWAAEDHVLRDSEENRKLQRKL 86

[Close]

BLAST of MRG-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007775.1 (pep scaffold:Pmarinus_7.0:GL479621:8992:20190:-1 gene:ENSPMAG00000007032.1 transcript:ENSPMAT00000007775.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 87.0409 bits (214), Expect = 6.680e-21
Identity = 51/137 (37.23%), Postives = 81/137 (59.12%), Query Frame = 3

Query:  768 TVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLL 1178
            T +  +T+++ + V   K    E L+ WL DDWDLITRQ +L  LP + +VD +L  Y ++    +   G+++   NK   +  + V G+R+YFN  +G+ LLYKFER QY +++  +     MS +YG+ +LLRL 
Sbjct:    2 TCVQEETFMSRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKNVDSILEDYSNY----KKSRGNSD---NKEYAVS-DVVAGIREYFNVMLGTQLLYKFERPQYADIL-ADHPDAPMSHVYGAPHLLRLF 126

[Close]

BLAST of MRG-1 vs. Ensembl Sea Lamprey
Match: arid4a (AT rich interactive domain 4A (RBP1-like) [Source:ZFIN;Acc:ZDB-GENE-050809-105])

HSP 1 Score: 50.8322 bits (120), Expect = 5.963e-7
Identity = 26/72 (36.11%), Postives = 41/72 (56.94%), Query Frame = 3

Query:   84 PLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQK 299
            PL + ++ KY  G+ L  Y    + +    E +E S++ YL+HY GWN  +DEWV + RI++  +  I K K
Sbjct:  587 PLGTKVRVKYGRGKSLKIYEA--IIKDVDTEGEEDSDVIYLVHYYGWNVRYDEWVKEDRIIRPVDKNIPKIK 656

[Close]

BLAST of MRG-1 vs. Ensembl Yeast
Match: EAF3 (Component of the Rpd3S histone deacetylase complex; Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition [Source:SGD;Acc:S000006227])

HSP 1 Score: 85.5001 bits (210), Expect = 1.282e-18
Identity = 56/199 (28.14%), Postives = 103/199 (51.76%), Query Frame = 3

Query:  789 YVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSS-----IYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLED--------YITATADYTRRAM 1346
            ++ G     +       L+  L DDW+ +T+  ++ RLP  ++V+ VL +Y+        +E ++ G    ++    E+  G++ YF+  +G++LLY+ ER QY E++   +S KD        IYG+++LLRL+  + +LIS T  D+ S   L    + F+ +L  +VDE+F  +D        Y+  ++ Y   A+
Sbjct:  211 HIAGYPTPKISLQIPIKLKSVLVDDWEYVTKDKKICRLPADVTVEMVLNKYEHEVS----QELESPG----SQSQLSEYCAGLKLYFDKCLGNMLLYRLERLQYDELLK--KSSKDQKPLVPIRIYGAIHLLRLISVLPELISSTTMDLQSCQLLIKQTEDFLVWLLMHVDEYFNDKDPNRSDDALYVNTSSQYEGVAL 399

HSP 2 Score: 61.6178 bits (148), Expect = 8.546e-11
Identity = 33/111 (29.73%), Postives = 51/111 (45.95%), Query Frame = 3

Query:   96 DIKPKYSIGEKLLCYHGPLLYEAKCIEI--------------------QESSEIR-------------------YLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQD 311
            D++ ++++G + L +HGPL+YEAK ++I                    Q + EI+                   + IHYQGW  +WDEWV   RI  +NE  I  +K L +
Sbjct:    3 DLEQEFALGGRCLAFHGPLMYEAKILKIWDPSSKMYTSIPNDKPGGSSQATKEIKPQKLGEDESIPEEIINGKCFFIHYQGWKSSWDEWVGYDRIRAYNEENIAMKKRLAN 113

[Close]

BLAST of MRG-1 vs. Ensembl Nematostella
Match: EDO49765 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFQ8])

HSP 1 Score: 122.865 bits (307), Expect = 1.101e-31
Identity = 72/195 (36.92%), Postives = 108/195 (55.38%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRA 1343
            L+ T+ + + YV  ++V   K V  ++L+ WL DDW+LITRQ +L  LP + +V D+L  Y  H    +   G   G          E  +G+++YFN  +G+ LLYKFER QY E++  N S   MS +YG+ +LLRL V +   +SY+  D   +  +   IQ  ++++  N D  F   DY TAT +Y RRA
Sbjct:  125 LNNTLDNDENYVPRVDV---KIVIPDDLKQWLVDDWELITRQKQLVPLPRKKTVADILDEYAKHRA--KTSNGVKPGVVR-------EVADGIQEYFNVMLGTQLLYKFERPQYGEILVEN-SNLPMSQVYGAEHLLRLFVRLGSALSYSNLDEKGVKFIVHHIQDLLDYMVKNADNLFST-DYETATPEYHRRA 305

HSP 2 Score: 101.679 bits (252), Expect = 3.214e-24
Identity = 41/69 (59.42%), Postives = 57/69 (82.61%), Query Frame = 3

Query:  108 KYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQD 311
            K++ GE++LCYHGPL+YEAKCI  Q +    RYLIHY GWNK WDEWV ++R+LK+N+A ++KQ+EL++
Sbjct:    6 KFAEGERVLCYHGPLIYEAKCIRGQLKEKTARYLIHYNGWNKNWDEWVPESRVLKYNDANLQKQRELRE 74

[Close]

BLAST of MRG-1 vs. Ensembl Nematostella
Match: EDO38666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCD5])

HSP 1 Score: 53.5286 bits (127), Expect = 3.003e-9
Identity = 28/80 (35.00%), Postives = 45/80 (56.25%), Query Frame = 3

Query:  105 PKYSIGEKLLCYH-----GPLLYEAKCIEIQESSEIR------YLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQD 311
            PK+  G+ +LCY        +LYEAK +E+  + + +      Y IH+ GWNK+WD WV +  +LK +EA    + +L +
Sbjct:   12 PKHEQGDTVLCYEPDPTKARVLYEAKVLEVDITKDEKGKKVPEYFIHFNGWNKSWDRWVVEESVLKNSEANQALKAKLHE 91

[Close]

BLAST of MRG-1 vs. Ensembl Medaka
Match: ENSORLT00000002558.2 (mortality factor 4-like protein 1 [Source:NCBI gene;Acc:101169275])

HSP 1 Score: 125.561 bits (314), Expect = 3.380e-32
Identity = 74/196 (37.76%), Postives = 109/196 (55.61%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   + +   + V   K    E L+ WL DDWDLITRQ +L  LP + SVD VL  Y ++    +  +G+++   NK   +  E V G+R+YFN  +G+ LLYKFER QY E++        MS +YG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  140 VDPTVESEEMFTNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKSVDMVLEDYANY----KKSKGNSD---NKEYAVN-EVVAGIREYFNVMLGTQLLYKFERPQYAEIL-AEHPDTPMSQVYGAPHLLRLFVRIGAMLAYTLLDEKSLALLLTYLQDFLKYLVKNSATLFSATDYEVAPPEYHRKAV 323

HSP 2 Score: 107.071 bits (266), Expect = 1.565e-25
Identity = 43/77 (55.84%), Postives = 60/77 (77.92%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D KPK+  GE++LC+HGPLLYEAKC++I  +  +I+Y IHY GWNK WDEWV ++R+LK+ ++ + KQ+ELQ
Sbjct:    1 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKISIKDKQIKYFIHYSGWNKNWDEWVPESRVLKYVDSNLAKQRELQ 77

[Close]

BLAST of MRG-1 vs. Ensembl Medaka
Match: ENSORLT00000002559.2 (mortality factor 4-like protein 1 [Source:NCBI gene;Acc:101169275])

HSP 1 Score: 124.79 bits (312), Expect = 3.773e-32
Identity = 74/196 (37.76%), Postives = 109/196 (55.61%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   + +   + V   K    E L+ WL DDWDLITRQ +L  LP + SVD VL  Y ++    +  +G+++   NK   +  E V G+R+YFN  +G+ LLYKFER QY E++        MS +YG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  113 VDPTVESEEMFTNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKSVDMVLEDYANY----KKSKGNSD---NKEYAVN-EVVAGIREYFNVMLGTQLLYKFERPQYAEIL-AEHPDTPMSQVYGAPHLLRLFVRIGAMLAYTLLDEKSLALLLTYLQDFLKYLVKNSATLFSATDYEVAPPEYHRKAV 296

HSP 2 Score: 104.76 bits (260), Expect = 7.436e-25
Identity = 42/76 (55.26%), Postives = 59/76 (77.63%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKEL 305
            M  K D KPK+  GE++LC+HGPLLYEAKC++I  +  +I+Y IHY GWNK WDEWV ++R+LK+ ++ + KQ+EL
Sbjct:    1 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKISIKDKQIKYFIHYSGWNKNWDEWVPESRVLKYVDSNLAKQREL 76

[Close]

BLAST of MRG-1 vs. Ensembl Medaka
Match: morf4l1 (mortality factor 4-like protein 1 [Source:NCBI gene;Acc:101170839])

HSP 1 Score: 125.176 bits (313), Expect = 4.529e-32
Identity = 75/196 (38.27%), Postives = 107/196 (54.59%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   +T++  + V   K    E L+ WL DDWDLITRQ +L  LP + +VD VL  Y ++ +  R      E   N       E V G+R+YFN  +G+ LLYKFER QY +++  N     MS IYG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  140 VDPTVESEETFINRVEV---KVKIPEELKPWLVDDWDLITRQKQLVHLPAKKNVDGVLEDYANYKKS-RGNSDSKEFAVN-------EVVAGIREYFNVMLGTQLLYKFERPQYADIL-ANHPDTPMSQIYGASHLLRLFVRIGAMLAYTPLDEKSLSLLLSYLQDFLKYLVKNSASLFNASDYEVAPPEYHRKAV 323

HSP 2 Score: 106.686 bits (265), Expect = 2.060e-25
Identity = 43/77 (55.84%), Postives = 60/77 (77.92%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D KPK+  GE++LC+HGPLLYEAKC++   +  +I+Y IHY GWNK WDEWV ++R+LK+ ++ ++KQKELQ
Sbjct:    1 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKTNIKDKQIKYFIHYSGWNKNWDEWVPESRVLKYVDSNLQKQKELQ 77

[Close]

BLAST of MRG-1 vs. Ensembl Medaka
Match: ENSORLT00000002555.2 (mortality factor 4-like protein 1 [Source:NCBI gene;Acc:101169275])

HSP 1 Score: 125.561 bits (314), Expect = 5.519e-32
Identity = 74/196 (37.76%), Postives = 109/196 (55.61%), Query Frame = 3

Query:  759 LDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAM 1346
            +D TV   + +   + V   K    E L+ WL DDWDLITRQ +L  LP + SVD VL  Y ++    +  +G+++   NK   +  E V G+R+YFN  +G+ LLYKFER QY E++        MS +YG+ +LLRL V I  +++YT  D  S+  L   +Q F+++L  N    F   DY  A  +Y R+A+
Sbjct:  152 VDPTVESEEMFTNRVEV---KVKIPEELKPWLVDDWDLITRQKQLFHLPAKKSVDMVLEDYANY----KKSKGNSD---NKEYAVN-EVVAGIREYFNVMLGTQLLYKFERPQYAEIL-AEHPDTPMSQVYGAPHLLRLFVRIGAMLAYTLLDEKSLALLLTYLQDFLKYLVKNSATLFSATDYEVAPPEYHRKAV 335

HSP 2 Score: 107.071 bits (266), Expect = 1.964e-25
Identity = 43/77 (55.84%), Postives = 60/77 (77.92%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQ-ESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQ 308
            M  K D KPK+  GE++LC+HGPLLYEAKC++I  +  +I+Y IHY GWNK WDEWV ++R+LK+ ++ + KQ+ELQ
Sbjct:    1 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKISIKDKQIKYFIHYSGWNKNWDEWVPESRVLKYVDSNLAKQRELQ 77

[Close]

BLAST of MRG-1 vs. Ensembl Medaka
Match: MSL3 (MSL complex subunit 3 [Source:NCBI gene;Acc:101160633])

HSP 1 Score: 50.447 bits (119), Expect = 2.938e-6
Identity = 24/80 (30.00%), Postives = 44/80 (55.00%), Query Frame = 3

Query:   99 IKPKYSIGEKLLCYH-----GPLLYEAKCIEIQESSE------IRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKEL 305
            IK  +  GE++LC+        +LY+AK +++   ++       +YLIH+ GW+++WD W  +  +L+  E   K Q+ L
Sbjct:    6 IKYHFHKGERVLCFEPDPSKAKVLYDAKVLDVLIGTDEHGRRVPKYLIHFNGWSRSWDRWAAEDHVLRDTEENRKLQRRL 85

[Close]

BLAST of MRG-1 vs. Planmine SMEST
Match: SMESG000022376.1 (SMESG000022376.1)

HSP 1 Score: 738.028 bits (1904), Expect = 0.000e+0
Identity = 423/423 (100.00%), Postives = 423/423 (100.00%), Query Frame = 3

Query:   81 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYXXXXXXXXXXXXXXXXXRKSSRSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTDAGTSVVSEELLXXXXXXXXXXXXXXXXXXXXXXXXNSEISVDKSLVTEEKSTIEDISLTNNEAXXXXXXXXXXXXXXXRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAMC 1349
            MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYKESRKKKDNRKKMINEKRKSSRSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTDAGTSVVSEELLDDQKSSIKDKSVSSKTRTRKRRLSNSEISVDKSLVTEEKSTIEDISLTNNEATNSNKSTNSSKSKKSRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAMC
Sbjct:    1 MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQESSEIRYLIHYQGWNKTWDEWVNDTRILKFNEAGIKKQKELQDLYKESRKKKDNRKKMINEKRKSSRSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTDAGTSVVSEELLDDQKSSIKDKSVSSKTRTRKRRLSNSEISVDKSLVTEEKSTIEDISLTNNEATNSNKSTNSSKSKKSRLVPLDETVLDLDTYVTGINVQSLKFVFTENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGDNEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESKKDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNNVDEFFKLEDYITATADYTRRAMC 423

The following BLAST results are available for this feature:

BLAST of MRG-1 vs. Ensembl Human
BLAST of MRG-1 vs. Ensembl Celegans
BLAST of MRG-1 vs. Ensembl Fly
BLAST of MRG-1 vs. Ensembl Zebrafish
BLAST of MRG-1 vs. Ensembl Xenopus
BLAST of MRG-1 vs. Ensembl Mouse
BLAST of MRG-1 vs. UniProt/SwissProt
BLAST of MRG-1 vs. TrEMBL
BLAST of MRG-1 vs. Ensembl Cavefish
BLAST of MRG-1 vs. Ensembl Sea Lamprey
BLAST of MRG-1 vs. Ensembl Yeast
BLAST of MRG-1 vs. Ensembl Nematostella
BLAST of MRG-1 vs. Ensembl Medaka
BLAST of MRG-1 vs. Planmine SMEST

BLAST of MRG-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MORF4L1	3.217e-33	36.22	mortality factor 4 like 1 [Source:HGNC Symbol;Acc:...	[more]
MORF4L1	3.217e-33	36.22	mortality factor 4 like 1 [Source:HGNC Symbol;Acc:...	[more]
MORF4L2	4.796e-33	36.46	mortality factor 4 like 2 [Source:HGNC Symbol;Acc:...	[more]
MORF4L2	1.677e-32	36.46	mortality factor 4 like 2 [Source:HGNC Symbol;Acc:...	[more]
MORF4L2	1.677e-32	36.46	mortality factor 4 like 2 [Source:HGNC Symbol;Acc:...	[more]

BLAST of MRG-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
mrg-1	2.645e-9	25.84	MRG (Mortality factor-Related Gene) related [Sour...	[more]
mrg-1	2.012e-8	26.07	MRG (Mortality factor-Related Gene) related [Sour...	[more]

BLAST of MRG-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
MRG15	4.710e-25	31.82	gene:FBgn0027378 transcript:FBtr0083125	[more]
MRG15	4.864e-25	31.82	gene:FBgn0027378 transcript:FBtr0333921	[more]

BLAST of MRG-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
morf4l1	7.372e-35	38.78	mortality factor 4 like 1 [Source:ZFIN;Acc:ZDB-GEN...	[more]
morf4l1	7.372e-35	38.78	mortality factor 4 like 1 [Source:ZFIN;Acc:ZDB-GEN...	[more]
morf4l1	1.082e-34	38.78	mortality factor 4 like 1 [Source:ZFIN;Acc:ZDB-GEN...	[more]

BLAST of MRG-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cog3	1.534e-32	36.22	component of oligomeric golgi complex 3 [Source:Xe...	[more]
cog3	4.578e-32	36.22	component of oligomeric golgi complex 3 [Source:Xe...	[more]
cog3	7.509e-32	36.22	component of oligomeric golgi complex 3 [Source:Xe...	[more]
cog3	1.578e-31	36.22	component of oligomeric golgi complex 3 [Source:Xe...	[more]
cog3	1.593e-31	36.22	component of oligomeric golgi complex 3 [Source:Xe...	[more]

BLAST of MRG-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Morf4l2	1.962e-33	37.85	mortality factor 4 like 2 [Source:MGI Symbol;Acc:M...	[more]
Morf4l2	1.962e-33	37.85	mortality factor 4 like 2 [Source:MGI Symbol;Acc:M...	[more]
Morf4l2	1.962e-33	37.85	mortality factor 4 like 2 [Source:MGI Symbol;Acc:M...	[more]
Morf4l2	1.962e-33	37.85	mortality factor 4 like 2 [Source:MGI Symbol;Acc:M...	[more]
Morf4l2	1.962e-33	37.85	mortality factor 4 like 2 [Source:MGI Symbol;Acc:M...	[more]

BLAST of MRG-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9R0Q4\|MO4L2_MOUSE	1.372e-32	37.85	Mortality factor 4-like protein 2 OS=Mus musculus ...	[more]
sp\|Q6QI89\|MO4L2_RAT	1.444e-32	37.85	Mortality factor 4-like protein 2 OS=Rattus norveg...	[more]
sp\|Q4R578\|MO4L2_MACFA	7.735e-32	36.46	Mortality factor 4-like protein 2 OS=Macaca fascic...	[more]
sp\|Q5R905\|MO4L2_PONAB	8.056e-32	36.46	Mortality factor 4-like protein 2 OS=Pongo abelii ...	[more]
sp\|A5A6J5\|MO4L2_PANTR	8.056e-32	36.46	Mortality factor 4-like protein 2 OS=Pan troglodyt...	[more]

BLAST of MRG-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H9CXT0	0.000e+0	100.00	MRG-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
A0A0A1XPQ2	3.567e-48	28.99	NuA4 complex subunit EAF3 homolog OS=Zeugodacus cu...	[more]
A0A087ZV33	4.540e-47	31.06	MRG domain-containing protein OS=Apis mellifera OX...	[more]
A0A1I8MAE3	7.108e-47	28.57	MRG domain-containing protein OS=Musca domestica O...	[more]
A0A0K8VCW1	2.636e-46	28.47	NuA4 complex subunit EAF3 OS=Bactrocera latifrons ...	[more]

BLAST of MRG-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
morf4l1	1.108e-34	38.78	mortality factor 4 like 1 [Source:NCBI gene;Acc:10...	[more]
morf4l1	1.232e-34	38.78	mortality factor 4 like 1 [Source:NCBI gene;Acc:10...	[more]
MSL3	7.810e-8	34.57	MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC...	[more]
MSL3	9.889e-8	34.57	MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC...	[more]
MSL3	1.086e-7	34.57	MSL complex subunit 3 [Source:HGNC Symbol;Acc:HGNC...	[more]

BLAST of MRG-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000007775.1	6.680e-21	37.23	pep scaffold:Pmarinus_7.0:GL479621:8992:20190:-1 g...	[more]
arid4a	5.963e-7	36.11	AT rich interactive domain 4A (RBP1-like) [Source:...	[more]

BLAST of MRG-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
EAF3	1.282e-18	28.14	Component of the Rpd3S histone deacetylase complex...	[more]

BLAST of MRG-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO49765	1.101e-31	36.92	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38666	3.003e-9	35.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of MRG-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000002558.2	3.380e-32	37.76	mortality factor 4-like protein 1 [Source:NCBI gen...	[more]
ENSORLT00000002559.2	3.773e-32	37.76	mortality factor 4-like protein 1 [Source:NCBI gen...	[more]
morf4l1	4.529e-32	38.27	mortality factor 4-like protein 1 [Source:NCBI gen...	[more]
ENSORLT00000002555.2	5.519e-32	37.76	mortality factor 4-like protein 1 [Source:NCBI gen...	[more]
MSL3	2.938e-6	30.00	MSL complex subunit 3 [Source:NCBI gene;Acc:101160...	[more]

BLAST of MRG-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000022376.1	0.000e+0	100.00	SMESG000022376.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30015533
GenBank	AFD29601.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30015533 ID=SMED30015533|Name=MRG-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1363bp
ATAAAGTAGACATTTTAAAATTATAATTTGATATTAAATTTTAAATTTGA
GACAATTATCTATTTATGCTTATTTTTTAAATGCCTCTGAAATCTGATAT
AAAGCCTAAATATTCAATAGGTGAAAAATTACTCTGCTATCACGGACCCT
TGCTTTATGAAGCAAAGTGTATTGAAATTCAGGAAAGTTCTGAAATTCGA
TATCTTATACACTACCAAGGATGGAATAAAACTTGGGATGAATGGGTTAA
TGATACAAGAATATTGAAATTTAATGAGGCTGGAATCAAAAAGCAAAAAG
AATTGCAAGATCTTTATAAGGAATCTCGAAAGAAAAAAGATAATAGAAAA
AAAATGATAAACGAAAAACGCAAATCTAGTCGTAGTTCTCAAGATAAGAT
TCGTTTCATGGGTTCGGCTTCTGAAACATCAAATCGTAGTTTTGGTGAAT
CAGAAGACGGCAAGGCTTCTAAAATAACTACAGAAGATGAAAATTTAGAA
AATAAAACTGATGCTGGAACATCGGTTGTAAGTGAAGAGCTATTAGATGA
TCAAAAATCATCCATAAAAGATAAATCTGTGTCATCAAAGACAAGAACAA
GAAAGCGCCGCCTGTCTAATAGTGAAATAAGTGTTGATAAATCTCTAGTG
ACAGAAGAAAAATCAACAATCGAAGATATTTCGCTAACTAATAATGAAGC
TACTAATTCTAATAAATCTACAAACAGTTCGAAATCAAAAAAAAGTCGAC
TAGTTCCATTAGATGAAACTGTTTTGGATTTGGACACCTATGTCACCGGA
ATCAACGTTCAATCGCTTAAATTTGTTTTCACTGAAAATCTTCGATTATG
GTTGGCTGATGATTGGGATTTAATAACCCGCCAATCGCGTCTTTCTCGTT
TGCCGACTCGAATGTCGGTCGATGATGTTTTAGCACGATATAAATCCCAT
TGCGAATGTCTTCGAATGGAGGAAGGAGACAACGAAGGATTCTTCAACAA
AAACCGAGACATGCGTTTCGAATTCGTTGAAGGAATGAGAAAGTATTTCA
ATACGTCCATCGGTTCGTTATTGTTGTACAAATTTGAGCGGCAGCAATAT
TTTGAAGTTGTCAACACCAACGAATCGAAAAAGGACATGAGCAGCATTTA
CGGTTCCATGTATTTATTGAGATTATTAGTTAATATAAAGAAACTTATTT
CCTACACTCGTACCGATGTGCCGAGTATTGATTGTTTAGGAGACTTGATA
CAGCATTTCATTGAGTTTTTAGATAATAATGTTGACGAGTTTTTCAAATT
GGAAGATTACATAACGGCAACTGCGGATTACACTCGCAGGGCAATGTGTT
GAATGTTGTAATG

protein sequence of SMED30015533-orf-1

>SMED30015533-orf-1 ID=SMED30015533-orf-1|Name=SMED30015533-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=424bp
MPLKSDIKPKYSIGEKLLCYHGPLLYEAKCIEIQESSEIRYLIHYQGWNK
TWDEWVNDTRILKFNEAGIKKQKELQDLYKESRKKKDNRKKMINEKRKSS
RSSQDKIRFMGSASETSNRSFGESEDGKASKITTEDENLENKTDAGTSVV
SEELLDDQKSSIKDKSVSSKTRTRKRRLSNSEISVDKSLVTEEKSTIEDI
SLTNNEATNSNKSTNSSKSKKSRLVPLDETVLDLDTYVTGINVQSLKFVF
TENLRLWLADDWDLITRQSRLSRLPTRMSVDDVLARYKSHCECLRMEEGD
NEGFFNKNRDMRFEFVEGMRKYFNTSIGSLLLYKFERQQYFEVVNTNESK
KDMSSIYGSMYLLRLLVNIKKLISYTRTDVPSIDCLGDLIQHFIEFLDNN
VDEFFKLEDYITATADYTRRAMC*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000429	neoblast
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR038217	MRG_C_sf
IPR008676	MRG
IPR000953	Chromo/chromo_shadow_dom
IPR026541	MRG_dom
IPR025995	Tudor-knot
IPR016197	Chromo-like_dom_sf

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

Vocabulary: **biological process**
Term	Definition
GO:0006325	chromatin organization
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 75..95
None	No IPR available	GENE3D	G3DSA:2.30.30.140		coord: 2..93 e-value: 1.8E-31 score: 110.0
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 121..142
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 201..221
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 105..120
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 201..222
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 81..180
None	No IPR available	CDD	cd18983	CBD_MSL3_like	coord: 15..70 e-value: 9.39261E-19 score: 77.4893
IPR000953	Chromo/chromo shadow domain	SMART	SM00298	chromo_7	coord: 10..77 e-value: 6.5E-4 score: 29.0
IPR026541	MRG domain	PFAM	PF05712	MRG	coord: 247..411 e-value: 2.0E-39 score: 135.0
IPR026541	MRG domain	PROSITE	PS51640	MRG	coord: 242..422 score: 46.412
IPR038217	MRG, C-terminal domain superfamily	GENE3D	G3DSA:1.10.274.30		coord: 241..423 e-value: 2.2E-48 score: 165.9
IPR025995	RNA binding activity-knot of a chromodomain	PFAM	PF11717	Tudor-knot	coord: 13..61 e-value: 3.6E-12 score: 46.0
IPR008676	MRG	PANTHER	PTHR10880	MORTALITY FACTOR 4-LIKE PROTEIN	coord: 7..421
IPR016197	Chromo-like domain superfamily	SUPERFAMILY	SSF54160	Chromo domain-like	coord: 5..267