Tyrosine-protein kinase

Overview
NameTyrosine-protein kinase
Smed IDSMED30015527
Length (bp)1660
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Tyrosine-protein kinase (SMED30015527) t-SNE clustered cells

Violin plots show distribution of expression levels for Tyrosine-protein kinase (SMED30015527) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tyrosine-protein kinase (SMED30015527) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tyrosine-protein kinase (SMED30015527) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30015527

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30015527SMESG000077919.1 dd_Smed_v4_5996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30015527SMESG000077919.1 dd_Smed_v4_5996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30015527SMESG000077919.1 dd_Smed_v4_5996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015527SMESG000077919.1 SMESG000077918.1 Contig44249newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015527SMESG000077919.1 SMESG000077918.1 Contig44249uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015527SMESG000077919.1 Contig35040newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30015527SMESG000077919.1 Contig35040uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283])

HSP 1 Score: 299.671 bits (766), Expect = 1.777e-94
Identity = 164/440 (37.27%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 515
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283])

HSP 1 Score: 299.671 bits (766), Expect = 1.777e-94
Identity = 164/440 (37.27%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 515
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283])

HSP 1 Score: 299.671 bits (766), Expect = 1.777e-94
Identity = 164/440 (37.27%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 515
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283])

HSP 1 Score: 293.123 bits (749), Expect = 7.268e-92
Identity = 164/446 (36.77%), Postives = 246/446 (55.16%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEI------DENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN        + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 521
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Match: FRK (fyn related Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:3955])

HSP 1 Score: 288.886 bits (738), Expect = 1.117e-90
Identity = 169/459 (36.82%), Postives = 260/459 (56.64%), Query Frame = 3 
Query:  177 HYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENW-----LEVVKPQS--QIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKE-NSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA--------RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVKNTR----FPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            HY V A + Y+A    D+SF   + +QV++ + E W     LE  +  S  Q++G IPS+YV++    Q     +  I R +AEK L+    + G+++IR S  +   F+LSV D         V+H++IK  +  G   +++  + F ++   +  + KT  G          +I++ +PF  +Y+    +   EI+R+++ +L  +G G FG V+   W     VAVK +     + N FL+EA+IM  LRH K+++L  +C+   E PI II E M++GSL+ YL +D    + L++ V M A +A GM+YLES+N +HRDL A N+LV      KVADFGL   FK D  ++  +R     P KWTAPEA +S  F+ KSD+WSFG+++YE++T+GKMPY  +   +VI +L   YR+P P        CP   Y IM+ECWN +P++RP+F  L
Sbjct:   45 HYFV-ALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAV------VKHYRIKRLDEGG--FFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQW---EIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCT--LEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSN------CPQQFYNIMLECWNAEPKERPTFETL 483
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-2 (Tyrosine protein-kinase src-2 [Source:UniProtKB/Swiss-Prot;Acc:O45539])

HSP 1 Score: 270.396 bits (690), Expect = 6.452e-84
Identity = 157/481 (32.64%), Postives = 268/481 (55.72%), Query Frame = 3 
Query:   72 MGQTQSSENLRKSSRNKIVSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSR-KENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQP---PIHFQD-IEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVK---NTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            +G+     + R  S   I + +  N+I+  +         A ++Y+A  + D+SF+ ++I++++N+   +W       +   G IPS+YV+++   +     +  ++R +AEK L+    E G +++R S  +++  +LSVR+   N     V+H++I+  +  G   +I+  + F ++  +I  +++   G   + L +P   +  P      + D  E++R +V ++ +IG G FG V+  +W     VAVK + +  ++   FL EA+IM KLRH K++ L  +C+  ++ PILI+ E M+   L  +L   + R   + ++V + A +A GM+YLE  N +HRDL A NIL++  L+VK+ADFGL      +NE +     RFP KWTAPEAA    FT+KSD+WSFG+++ E+VT+G++PYP +    V+  +  GYRMP P        CP  +Y IM +CW   P+KRP+F  L
Sbjct:   24 LGRESLPSHPRIPSIGPIAASSSGNTIDKNQNISQSANFVALFQYDARTDDDLSFKKDDILEILNDTQGDWWFARHKATGRTGYIPSNYVAREKSIESQPWYFGKMRRIDAEKCLLHTLNEHGAFLVRDSESRQHDLSLSVRE---NDS---VKHYRIRQLDHGG--YFIARRRPFATLHDLIAHYQREADGLC-VNLGAPCAKSEAPQTTTFTYDDQWEVDRRSVRLIRQIGAGQFGEVWEGRWNVNVPVAVKKLKAGTADPTDFLAEAQIMKKLRHPKLLSLYAVCT--RDEPILIVTELMQENLLT-FLQR-RGRQCQMPQLVEISAQVAAGMAYLEEMNFIHRDLAARNILINNSLSVKIADFGLARILMKENEYEARTGARFPIKWTAPEAANYNRFTTKSDVWSFGILLTEIVTFGRLPYPGMTNAEVLQQVDAGYRMPCP------AGCPVTLYDIMQQCWRSDPDKRPTFETL 485
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 264.618 bits (675), Expect = 5.023e-82
Identity = 156/454 (34.36%), Postives = 253/454 (55.73%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKEN-SFALSVRDLCKNSKIFRVRHFQIK-ISESKGKVLYISGNQKFYSIPSMIKFFRKTGIG-NARIRLKSPFPDNYQPPIHF---QDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLT----VKVADFGLTE--FKDDKNEVK-NTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIY-QIMVECWNDKPEKRPSFSCLLDRF 1502
            T+ A Y Y++  + D+SF+  + M +++  + +W  V   ++   G +P ++V+KQ   +        I R  AE+L++   L KGT++IR    +   FAL++RD         V+H++IK +   +G   +I+  + F S+  +++++     G   ++   +P     +P +     Q+ EI R+ +++  ++G G FG V+  KW    EVA+K M         FLQEA+IM +  H  +V+L  +C+  +E P  II E+M NGSL  YL +D    L +  +V M A IA GM YLE + +VHRDL A N+LV   ++    VKVADFGL     ++D  E +   +FP KWTAPEAA    FT KSD+WS+G+++YE++T G++PYP +    V++ +  GYRMP P        CP  IY +++++CW+  P++RP+F  L   F
Sbjct:   19 TLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQG--YFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCT--REEPFYIITEYMINGSLLQYLRTDGS-TLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPR------GCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFF 461
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 264.233 bits (674), Expect = 2.698e-81
Identity = 156/454 (34.36%), Postives = 253/454 (55.73%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKEN-SFALSVRDLCKNSKIFRVRHFQIK-ISESKGKVLYISGNQKFYSIPSMIKFFRKTGIG-NARIRLKSPFPDNYQPPIHF---QDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLT----VKVADFGLTE--FKDDKNEVK-NTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIY-QIMVECWNDKPEKRPSFSCLLDRF 1502
            T+ A Y Y++  + D+SF+  + M +++  + +W  V   ++   G +P ++V+KQ   +        I R  AE+L++   L KGT++IR    +   FAL++RD         V+H++IK +   +G   +I+  + F S+  +++++     G   ++   +P     +P +     Q+ EI R+ +++  ++G G FG V+  KW    EVA+K M         FLQEA+IM +  H  +V+L  +C+  +E P  II E+M NGSL  YL +D    L +  +V M A IA GM YLE + +VHRDL A N+LV   ++    VKVADFGL     ++D  E +   +FP KWTAPEAA    FT KSD+WS+G+++YE++T G++PYP +    V++ +  GYRMP P        CP  IY +++++CW+  P++RP+F  L   F
Sbjct:   75 TLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQG--YFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCT--REEPFYIITEYMINGSLLQYLRTDGS-TLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPR------GCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFF 517
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 264.233 bits (674), Expect = 2.698e-81
Identity = 156/454 (34.36%), Postives = 253/454 (55.73%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKEN-SFALSVRDLCKNSKIFRVRHFQIK-ISESKGKVLYISGNQKFYSIPSMIKFFRKTGIG-NARIRLKSPFPDNYQPPIHF---QDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLT----VKVADFGLTE--FKDDKNEVK-NTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIY-QIMVECWNDKPEKRPSFSCLLDRF 1502
            T+ A Y Y++  + D+SF+  + M +++  + +W  V   ++   G +P ++V+KQ   +        I R  AE+L++   L KGT++IR    +   FAL++RD         V+H++IK +   +G   +I+  + F S+  +++++     G   ++   +P     +P +     Q+ EI R+ +++  ++G G FG V+  KW    EVA+K M         FLQEA+IM +  H  +V+L  +C+  +E P  II E+M NGSL  YL +D    L +  +V M A IA GM YLE + +VHRDL A N+LV   ++    VKVADFGL     ++D  E +   +FP KWTAPEAA    FT KSD+WS+G+++YE++T G++PYP +    V++ +  GYRMP P        CP  IY +++++CW+  P++RP+F  L   F
Sbjct:   75 TLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQG--YFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCT--REEPFYIITEYMINGSLLQYLRTDGS-TLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPR------GCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFF 517
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Match: src-1 (Tyrosine protein-kinase src-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EE56])

HSP 1 Score: 264.233 bits (674), Expect = 3.536e-81
Identity = 156/454 (34.36%), Postives = 253/454 (55.73%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKEN-SFALSVRDLCKNSKIFRVRHFQIK-ISESKGKVLYISGNQKFYSIPSMIKFFRKTGIG-NARIRLKSPFPDNYQPPIHF---QDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLT----VKVADFGLTE--FKDDKNEVK-NTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIY-QIMVECWNDKPEKRPSFSCLLDRF 1502
            T+ A Y Y++  + D+SF+  + M +++  + +W  V   ++   G +P ++V+KQ   +        I R  AE+L++   L KGT++IR    +   FAL++RD         V+H++IK +   +G   +I+  + F S+  +++++     G   ++   +P     +P +     Q+ EI R+ +++  ++G G FG V+  KW    EVA+K M         FLQEA+IM +  H  +V+L  +C+  +E P  II E+M NGSL  YL +D    L +  +V M A IA GM YLE + +VHRDL A N+LV   ++    VKVADFGL     ++D  E +   +FP KWTAPEAA    FT KSD+WS+G+++YE++T G++PYP +    V++ +  GYRMP P        CP  IY +++++CW+  P++RP+F  L   F
Sbjct:   79 TLVALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAGKIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQG--YFITTRRTFRSLQELVRYYSDVPDGLCCQLTFPAPRLAPTRPDLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVEVAIKTMKPGTMSPEAFLQEAQIMKQCDHPNLVKLYAVCT--REEPFYIITEYMINGSLLQYLRTDGS-TLGIQALVDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPR------GCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFF 521
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100508)

HSP 1 Score: 294.278 bits (752), Expect = 1.983e-92
Identity = 161/450 (35.78%), Postives = 260/450 (57.78%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKE-NSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDI--------EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEF--KDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            V A Y Y++  E D+SF   + M+V+++ + +W  VV   ++ +GLIP ++V+++         ++++ R EA+KLL+     +GT+++RPS    N ++LSV+D  ++ + + V+H++IK  ++ G   YI+ NQ F S+ +++  + K  +G   I L  P P   +P     D+        EI R  + +L ++G G FG V+  KW  + +VAVK +         FLQEA IM K RH ++V L  +CS  QE PI I+ E+M  GSL  +L     R L    ++++   +A GM YLESK ++HRDL A N+L+  +   K+ DFGL      D+    + +RFP KWTAPEA     F+ KSD+WS+G+++ E+ T+G++PYP + +  VI+ +  G+RMP P   Y     P+ IYQ++++CW+  PEKRP+F  L   F
Sbjct:  100 VVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDW-EDGRGYHVKHYRIKPLDNGG--YYIATNQTFPSLQALVMAYSKNALGLCHI-LSRPCP---KPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCS--QEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHY----FPDNIYQLLLQCWDAVPEKRPTFEFLNHYF 536
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100505)

HSP 1 Score: 294.278 bits (752), Expect = 1.983e-92
Identity = 161/450 (35.78%), Postives = 260/450 (57.78%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKE-NSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDI--------EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEF--KDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            V A Y Y++  E D+SF   + M+V+++ + +W  VV   ++ +GLIP ++V+++         ++++ R EA+KLL+     +GT+++RPS    N ++LSV+D  ++ + + V+H++IK  ++ G   YI+ NQ F S+ +++  + K  +G   I L  P P   +P     D+        EI R  + +L ++G G FG V+  KW  + +VAVK +         FLQEA IM K RH ++V L  +CS  QE PI I+ E+M  GSL  +L     R L    ++++   +A GM YLESK ++HRDL A N+L+  +   K+ DFGL      D+    + +RFP KWTAPEA     F+ KSD+WS+G+++ E+ T+G++PYP + +  VI+ +  G+RMP P   Y     P+ IYQ++++CW+  PEKRP+F  L   F
Sbjct:  100 VVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDW-EDGRGYHVKHYRIKPLDNGG--YYIATNQTFPSLQALVMAYSKNALGLCHI-LSRPCP---KPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCS--QEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHY----FPDNIYQLLLQCWDAVPEKRPTFEFLNHYF 536
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0100504)

HSP 1 Score: 294.278 bits (752), Expect = 1.983e-92
Identity = 161/450 (35.78%), Postives = 260/450 (57.78%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKE-NSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDI--------EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEF--KDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            V A Y Y++  E D+SF   + M+V+++ + +W  VV   ++ +GLIP ++V+++         ++++ R EA+KLL+     +GT+++RPS    N ++LSV+D  ++ + + V+H++IK  ++ G   YI+ NQ F S+ +++  + K  +G   I L  P P   +P     D+        EI R  + +L ++G G FG V+  KW  + +VAVK +         FLQEA IM K RH ++V L  +CS  QE PI I+ E+M  GSL  +L     R L    ++++   +A GM YLESK ++HRDL A N+L+  +   K+ DFGL      D+    + +RFP KWTAPEA     F+ KSD+WS+G+++ E+ T+G++PYP + +  VI+ +  G+RMP P   Y     P+ IYQ++++CW+  PEKRP+F  L   F
Sbjct:  100 VVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDW-EDGRGYHVKHYRIKPLDNGG--YYIATNQTFPSLQALVMAYSKNALGLCHI-LSRPCP---KPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCS--QEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHY----FPDNIYQLLLQCWDAVPEKRPTFEFLNHYF 536
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0304990)

HSP 1 Score: 294.278 bits (752), Expect = 1.983e-92
Identity = 161/450 (35.78%), Postives = 260/450 (57.78%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKE-NSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDI--------EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEF--KDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            V A Y Y++  E D+SF   + M+V+++ + +W  VV   ++ +GLIP ++V+++         ++++ R EA+KLL+     +GT+++RPS    N ++LSV+D  ++ + + V+H++IK  ++ G   YI+ NQ F S+ +++  + K  +G   I L  P P   +P     D+        EI R  + +L ++G G FG V+  KW  + +VAVK +         FLQEA IM K RH ++V L  +CS  QE PI I+ E+M  GSL  +L     R L    ++++   +A GM YLESK ++HRDL A N+L+  +   K+ DFGL      D+    + +RFP KWTAPEA     F+ KSD+WS+G+++ E+ T+G++PYP + +  VI+ +  G+RMP P   Y     P+ IYQ++++CW+  PEKRP+F  L   F
Sbjct:  100 VVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDW-EDGRGYHVKHYRIKPLDNGG--YYIATNQTFPSLQALVMAYSKNALGLCHI-LSRPCP---KPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCS--QEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHY----FPDNIYQLLLQCWDAVPEKRPTFEFLNHYF 536
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Match: Src64B (gene:FBgn0262733 transcript:FBtr0304989)

HSP 1 Score: 294.278 bits (752), Expect = 1.983e-92
Identity = 161/450 (35.78%), Postives = 260/450 (57.78%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKE-NSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDI--------EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEF--KDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            V A Y Y++  E D+SF   + M+V+++ + +W  VV   ++ +GLIP ++V+++         ++++ R EA+KLL+     +GT+++RPS    N ++LSV+D  ++ + + V+H++IK  ++ G   YI+ NQ F S+ +++  + K  +G   I L  P P   +P     D+        EI R  + +L ++G G FG V+  KW  + +VAVK +         FLQEA IM K RH ++V L  +CS  QE PI I+ E+M  GSL  +L     R L    ++++   +A GM YLESK ++HRDL A N+L+  +   K+ DFGL      D+    + +RFP KWTAPEA     F+ KSD+WS+G+++ E+ T+G++PYP + +  VI+ +  G+RMP P   Y     P+ IYQ++++CW+  PEKRP+F  L   F
Sbjct:  100 VVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDW-EDGRGYHVKHYRIKPLDNGG--YYIATNQTFPSLQALVMAYSKNALGLCHI-LSRPCP---KPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHNRLVALYAVCS--QEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHY----FPDNIYQLLLQCWDAVPEKRPTFEFLNHYF 536
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: lyn (LYN proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040912-7])

HSP 1 Score: 295.049 bits (754), Expect = 4.622e-93
Identity = 170/445 (38.20%), Postives = 258/445 (57.98%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSR-KENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVK-NTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSF---SCLLDRF 1502
            V A Y YEA+   D+ F+  E ++++ E  E W +     ++ +G IPS+YV++ D  +     ++DI R +AE+ L+    + G+Y+IR S   + S++LS+RD+    +   V+H++I+  ++ G   YIS    F  I SMIK + K   G  R   K+      Q P      EI++D++ M+ ++G G FG V+ A +  + +VAVK +         FL+EA +M  L+H ++V L  + ++ +  PI II E+M NGSL  +L S     + L K++   A IAEGM+Y+E KN +HRDLRA N+LV   L  K+ADFGL    +DD+   +   +FP KWTAPEA     FT KSD+WSFGV++YE++T+GK+PYP +  + V+  +  GYRMP PE       CP  +Y+IM  CW +KPE RP+F     +LD F
Sbjct:   66 VVALYPYEAIHADDLGFKKGEKLKIIEEHGE-WWKARSLTTRKEGFIPSNYVAEADTMETEEWFYKDITRKDAERQLLAPANKPGSYLIRESETSKGSYSLSIRDVDAQGQDV-VKHYKIRSLDNGG--YYISPKITFSDISSMIKHYHKQSDGLCRKLDKACEKPKAQKPWDKDAWEISKDSIKMVKKLGAGQFGEVWMAFYNNSTKVAVKTLKPGTMSVEAFLEEANLMKTLQHDRLVRLYAVVTKTE--PIYIITEYMANGSLLDFLKSQAGSKIQLPKLIDFSAQIAEGMAYIEKKNYIHRDLRAANVLVSEMLLCKIADFGLARVIEDDQYTAREGAKFPIKWTAPEAINYGSFTIKSDMWSFGVLLYEIITYGKIPYPGMSNSEVMSSVQRGYRMPRPEN------CPVELYEIMTTCWKNKPEDRPTFDYIQSVLDDF 498
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: src (v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog [Source:NCBI gene;Acc:325084])

HSP 1 Score: 293.893 bits (751), Expect = 2.074e-92
Identity = 165/442 (37.33%), Postives = 250/442 (56.56%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIH--FQDI-EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+    D+SF   E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R ++E+LL+ +   +GT+++R S   + ++ LSV D   N K   V+H++I+  +S G   YI+   +F ++  ++  +R+   G     L    P   +PP     +D  EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  D  ++L L ++V M + IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP+ ++++M+ CW  +PE+RP+F  L
Sbjct:   86 TFVALYDYESRTASDLSFRKGERLQIVNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRESETTKGAYCLSVLDY-DNVKGLNVKHYKIRKLDSGG--FYITSRTQFSTLQQLVNHYRQHADGLCH-SLTDVCP-VLKPPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCP------AECPDSLHELMLTCWRKEPEERPTFEYL 513
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: src (v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog [Source:NCBI gene;Acc:325084])

HSP 1 Score: 293.893 bits (751), Expect = 2.074e-92
Identity = 165/442 (37.33%), Postives = 250/442 (56.56%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIH--FQDI-EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+    D+SF   E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R ++E+LL+ +   +GT+++R S   + ++ LSV D   N K   V+H++I+  +S G   YI+   +F ++  ++  +R+   G     L    P   +PP     +D  EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  D  ++L L ++V M + IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP+ ++++M+ CW  +PE+RP+F  L
Sbjct:   86 TFVALYDYESRTASDLSFRKGERLQIVNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLENRRGTFLVRESETTKGAYCLSVLDY-DNVKGLNVKHYKIRKLDSGG--FYITSRTQFSTLQQLVNHYRQHADGLCH-SLTDVCP-VLKPPTQGLARDAWEIPRDSLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCP------AECPDSLHELMLTCWRKEPEERPTFEYL 513
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: blk (BLK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040724-106])

HSP 1 Score: 287.73 bits (735), Expect = 1.329e-90
Identity = 163/442 (36.88%), Postives = 256/442 (57.92%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGW--QDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNY-QPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLD 1496
            V A+Y ++   E D+ F+  + ++++ E  E WL      +  +G IPS+YV++    Q  V+ W  +D+ R + E+LL+  G + G++++R S   + +F+LS+RD         V+H++I+  ++ G   YIS +  F S+  ++K++ +T  G  + RL +P      Q P    + EI R+ + ++ ++G G FG V+   +    +VA+K +     E   FLQEA +M +L+H ++V+L  + +     PI I+ E+M NGSL  +L +D    L LSK++ M A IAEGM+Y+E KN +HRDLRA NILV   L  K+ADFGL    + +    +  +FP KWTAPEA     FT KSD+WSFG+++ E+VT+G++PYP +    VI  L   YRMP P+       CP  +Y IM +CW +KPE RP+F  L D
Sbjct:   43 VIAQYDFQPASENDLQFKKGDRLRIIKENGEWWL-AKSLVTGYEGFIPSTYVARAQTLQ--VERWFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPEQGDV-VKHYKIRALDNGG--YYISPSTSFSSLQELVKYYSRTADGLCQ-RLGNPCKSTAPQRPWAQDEWEIPRETLKLVKKLGAGQFGEVWMGFYKNNQKVAIKTLKEGTMEPEAFLQEANLMKQLQHERLVKLHAVVTR---EPIYIVTEYMANGSLLDFLKTDDGHKLKLSKLIDMTAQIAEGMAYIERKNYIHRDLRAANILVSETLHCKIADFGLARIIETEYTAQEGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRVPYPGMTNPEVIRNLDRNYRMPCPDA------CPGELYDIMTKCWMEKPEDRPTFEYLQD 468
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Match: blk (BLK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-040724-106])

HSP 1 Score: 287.73 bits (735), Expect = 1.329e-90
Identity = 163/442 (36.88%), Postives = 256/442 (57.92%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGW--QDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNY-QPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLD 1496
            V A+Y ++   E D+ F+  + ++++ E  E WL      +  +G IPS+YV++    Q  V+ W  +D+ R + E+LL+  G + G++++R S   + +F+LS+RD         V+H++I+  ++ G   YIS +  F S+  ++K++ +T  G  + RL +P      Q P    + EI R+ + ++ ++G G FG V+   +    +VA+K +     E   FLQEA +M +L+H ++V+L  + +     PI I+ E+M NGSL  +L +D    L LSK++ M A IAEGM+Y+E KN +HRDLRA NILV   L  K+ADFGL    + +    +  +FP KWTAPEA     FT KSD+WSFG+++ E+VT+G++PYP +    VI  L   YRMP P+       CP  +Y IM +CW +KPE RP+F  L D
Sbjct:   43 VIAQYDFQPASENDLQFKKGDRLRIIKENGEWWL-AKSLVTGYEGFIPSTYVARAQTLQ--VERWFFKDMNRRDTERLLLAPGNKPGSFLVRESETTKGAFSLSIRDSTPEQGDV-VKHYKIRALDNGG--YYISPSTSFSSLQELVKYYSRTADGLCQ-RLGNPCKSTAPQRPWAQDEWEIPRETLKLVKKLGAGQFGEVWMGFYKNNQKVAIKTLKEGTMEPEAFLQEANLMKQLQHERLVKLHAVVTR---EPIYIVTEYMANGSLLDFLKTDDGHKLKLSKLIDMTAQIAEGMAYIERKNYIHRDLRAANILVSETLHCKIADFGLARIIETEYTAQEGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTYGRVPYPGMTNPEVIRNLDRNYRMPCPDA------CPGELYDIMTKCWMEKPEDRPTFEYLQD 468
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161])

HSP 1 Score: 301.597 bits (771), Expect = 7.822e-96
Identity = 167/440 (37.95%), Postives = 243/440 (55.23%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       S   G IPS+YV+  D  Q        I R EAE+LL+ +   +GT+++R S   + ++ LSV D   N  +  V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  R L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P        CP  ++ +M +CW   PE+RP+F  L
Sbjct:   34 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGL-NVKHYKIRKLDSGG--FYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------DCPESLHDLMCQCWRKDPEERPTFEYL 461
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161])

HSP 1 Score: 301.212 bits (770), Expect = 1.167e-95
Identity = 167/440 (37.95%), Postives = 243/440 (55.23%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       S   G IPS+YV+  D  Q        I R EAE+LL+ +   +GT+++R S   + ++ LSV D   N  +  V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  R L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P        CP  ++ +M +CW   PE+RP+F  L
Sbjct:   36 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGL-NVKHYKIRKLDSGG--FYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------DCPESLHDLMCQCWRKDPEERPTFEYL 463
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161])

HSP 1 Score: 301.212 bits (770), Expect = 1.185e-95
Identity = 172/463 (37.15%), Postives = 249/463 (53.78%), Query Frame = 3 
Query:  114 RNKIVSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            + KI SKN               T  A Y YE+  E D+SF+  E +Q+VN  + +W       S   G IPS+YV+  D  Q        I R EAE+LL+ +   +GT+++R S   + ++ LSV D   N  +  V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  R L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P        CP  ++ +M +CW   PE+RP+F  L
Sbjct:   28 KGKIYSKNHGGVT----------TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGL-NVKHYKIRKLDSGG--FYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------DCPESLHDLMCQCWRKDPEERPTFEYL 468
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161])

HSP 1 Score: 301.212 bits (770), Expect = 2.185e-95
Identity = 167/440 (37.95%), Postives = 243/440 (55.23%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       S   G IPS+YV+  D  Q        I R EAE+LL+ +   +GT+++R S   + ++ LSV D   N  +  V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  R L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P        CP  ++ +M +CW   PE+RP+F  L
Sbjct:   58 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDANRGL-NVKHYKIRKLDSGG--FYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------DCPESLHDLMCQCWRKDPEERPTFEYL 485
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Match: cthrc1 (collagen triple helix repeat containing 1 [Source:Xenbase;Acc:XB-GENE-980161])

HSP 1 Score: 301.212 bits (770), Expect = 4.759e-95
Identity = 167/440 (37.95%), Postives = 243/440 (55.23%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       S   G IPS+YV+  D  Q        I R EAE+LL+ +   +GT+++R S   + ++ LSV D   N +   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  R L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P        CP  ++ +M +CW   PE+RP+F  L
Sbjct:   84 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDAN-RGLNVKHYKIRKLDSGG--FYITSRTQFSSLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------DCPESLHDLMCQCWRKDPEERPTFEYL 511
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397])

HSP 1 Score: 298.901 bits (764), Expect = 2.505e-94
Identity = 164/440 (37.27%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   87 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 514
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397])

HSP 1 Score: 298.901 bits (764), Expect = 2.505e-94
Identity = 164/440 (37.27%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   87 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 514
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397])

HSP 1 Score: 298.901 bits (764), Expect = 2.505e-94
Identity = 164/440 (37.27%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   87 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 514
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397])

HSP 1 Score: 292.352 bits (747), Expect = 1.002e-91
Identity = 164/446 (36.77%), Postives = 246/446 (55.16%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEI------DENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN        + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   87 TFVALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 520
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Match: Src (Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:98397])

HSP 1 Score: 292.352 bits (747), Expect = 1.002e-91
Identity = 164/446 (36.77%), Postives = 246/446 (55.16%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEI------DENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN        + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   87 TFVALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 520
[Close]
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P42687|SPK1_GIRTI (Tyrosine-protein kinase SPK-1 OS=Girardia tigrina OX=6162 PE=2 SV=1)

HSP 1 Score: 589.341 bits (1518), Expect = 0.000e+0
Identity = 288/480 (60.00%), Postives = 363/480 (75.62%), Query Frame = 3 
Query:   72 MGQTQSSENLRKSSRNKIVSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDK---NEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            MGQ + S   +K S+NK  SK Q+   +  + P   Y VKAKYKY A  + DISFE  EIM V+ + DE WL+VVK +   +GL+PS+YVSKQDGS +SV+ W++IQRWEAEK LMK+GL+KGTYIIRPSRKENS+ALSVRD  +  KI  V+HFQIK  + +  + Y    + F +I ++I+F+ K GIGN  I L  P PDNYQPP+HFQDIEINR+N+ +LNEIG G FGSV+RAKWGR+YEVA K++ S+K+ER  F+ EAKIMHKLRHRKIVELLG+C+EPQ+ P+LII+E+MKNGSLK YL +   +  +L++MVHMMA+I+EGM+YLES+ VVHRDLRADNILV  DLT KVADFGLTE  D      E K  RFP+KWTAPEAAKSK+FTSKSD+WS+G+VM+E++TW   PYPDI A  VI+ +  GYRMPNPE     V CP+ IY+IM+ CW+  PEKRP+F  L ++ 
Sbjct:    1 MGQ-KFSIKCKKQSKNKNTSKCQKIPKKAYEGPPGSYMVKAKYKYAASGDTDISFEEKEIMYVLEQFDEFWLKVVKQKDNKEGLVPSNYVSKQDGSPQSVEAWREIQRWEAEKSLMKIGLQKGTYIIRPSRKENSYALSVRDFDEKKKICIVKHFQIKTLQDEKGISYSVNIRNFPNILTLIQFYEKNGIGNTHIPLTDPMPDNYQPPVHFQDIEINRENIEILNEIGRGFFGSVHRAKWGRSYEVAAKMLQSSKAEREKFVLEAKIMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAEISEGMAYLESEKVVHRDLRADNILVANDLTRKVADFGLTELTDGSLGDQEKKTLRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILTWASSPYPDIPAKEVIEKVSKGYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKM 479
[Close]
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P13116|SRC2_XENLA (Tyrosine-protein kinase Src-2 OS=Xenopus laevis OX=8355 GN=src-b PE=2 SV=3)

HSP 1 Score: 300.827 bits (769), Expect = 3.822e-94
Identity = 167/440 (37.95%), Postives = 242/440 (55.00%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF   E +Q+VN  + +W       S   G IPS+YV+  D  Q        I R EAE+LL+ +   +GT+++R S   + ++ LSV D    S+   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  R L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P        CP  ++ +M +CW   PE+RP+F  L
Sbjct:   84 TFVALYDYESRTETDLSFRKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDY-DASRGLNVKHYKIRKLDSGG--FYITSRTQFSSLQQLVAYYSKHADGLCHRLTAVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------DCPESLHDLMFQCWRKDPEERPTFEYL 511
[Close]
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P12931|SRC_HUMAN (Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3)

HSP 1 Score: 299.671 bits (766), Expect = 8.534e-94
Identity = 164/440 (37.27%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 515
[Close]
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|P13115|SRC1_XENLA (Tyrosine-protein kinase Src-1 OS=Xenopus laevis OX=8355 GN=src-a PE=2 SV=4)

HSP 1 Score: 299.286 bits (765), Expect = 1.223e-93
Identity = 166/440 (37.73%), Postives = 243/440 (55.23%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       S   G IPS+YV+  D  Q        I R EAE+LL+ +   +GT+++R S   + ++ LSV D   N +   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI RD++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E++  GSL  +L  +  R L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P        CP  ++ +M +CW   PE+RP+F  L
Sbjct:   84 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDAN-RGLNVKHYKIRKLDSGG--FYITSRTQFISLQQLVAYYSKHADGLCHRLTTVCPTAKPQTQGLSRDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYISKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------DCPESLHDLMFQCWRKDPEERPTFEYL 511
[Close]
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Match: sp|Q9WUD9|SRC_RAT (Proto-oncogene tyrosine-protein kinase Src OS=Rattus norvegicus OX=10116 GN=Src PE=1 SV=4)

HSP 1 Score: 299.286 bits (765), Expect = 1.636e-93
Identity = 164/440 (37.27%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+  E D+SF+  E +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R E+E+LL+     +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++ ++ K   G   R+    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  +  + L L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP  ++ +M +CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDF-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPP------ECPESLHDLMCQCWRKEPEERPTFEYL 515
[Close]
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: G7YFZ5 (Tyrosine-protein kinase OS=Clonorchis sinensis OX=79923 GN=CLF_106945 PE=3 SV=1)

HSP 1 Score: 393.66 bits (1010), Expect = 1.914e-127
Identity = 193/446 (43.27%), Postives = 285/446 (63.90%), Query Frame = 3 
Query:  168 PFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            P     V+A Y Y    + D+ F   + M  V+++   W      ++   G IPS+YV   DG   S+D W DI R EA+K L+++G  KGTY+IR S +  ++ALSVR   +   I+ V+H++I++ ++     +IS    F +I  +I ++ +T  G    RL  P P +Y+PP+ F+D E+NR+++ M+ ++GHG FG VY AKW  + EVAVK M  + ++R  F++EA++MH+  H +IV+LLG+C++P++ P+ II E M  G+L  +L  D+ + L LS ++ MMA IA GM+YLE +N VHRDLRA NILVD D +VKV+DFGL +   DD     +T+FP KWTAPEAA   IF+ KSD+WSFGV+MYE+VT+G  PYP +   + I  +  GYR+PNP T   +  CP+ +Y IM++CW+ +PE RP+F  L D F
Sbjct:  103 PVKQIRVRALYTYTGQHQDDLPFRKGDTM-FVSDVSAQWWLARHQKTGATGYIPSNYVLIDDGLPTSLDAWYDISRREADKRLLRVGNPKGTYLIRSSSETQNYALSVRHYDQERNIYVVKHYRIRVLDNDNG-YFISNRITFPNIKDLISYYSRTAEGLC-CRLTVPCPRDYRPPVQFRDFEVNRNSITMVRQLGHGSFGEVYLAKWNDSVEVAVK-MRLSHTDRTKFIEEARLMHEFHHPRIVQLLGVCTQPEDEPVYIITELMAKGALVDFLRGDEGQQLSLSDLIDMMAQIASGMTYLEERNSVHRDLRAANILVDSDNSVKVSDFGLAKIISDDAQADHSTKFPIKWTAPEAALQHIFSIKSDVWSFGVLMYEIVTYGGTPYPGMSTRQTIVEVDKGYRLPNPHT--ANHPCPDDLYNIMLKCWDVRPENRPTFRSLYDVF 542
[Close]
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A4S2LUM5 (Tyrosine-protein kinase OS=Opisthorchis felineus OX=147828 GN=CRM22_004736 PE=3 SV=1)

HSP 1 Score: 393.66 bits (1010), Expect = 2.203e-127
Identity = 193/446 (43.27%), Postives = 285/446 (63.90%), Query Frame = 3 
Query:  168 PFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            P     V+A Y Y    + D+ F   + M  V+++   W      ++   G IPS+YV   DG   S+D W DI R EA+K L+++G  KGTY+IR S +  ++ALSVR   +   I+ V+H++I++ ++     +IS    F +I  +I ++ +T  G    RL  P P +Y+PP+ F+D E+NR+++ M+ ++GHG FG VY AKW  + EVAVK M  + ++R  F++EA++MH+  H +IV+LLG+C++P++ P+ II E M  G+L  +L  D+ + L LS ++ MMA IA GM+YLE +N VHRDLRA NILVD D +VKV+DFGL +   DD     +T+FP KWTAPEAA   IF+ KSD+WSFGV+MYE+VT+G  PYP +   + I  +  GYR+PNP T   +  CP+ +Y IM++CW+ +PE RP+F  L D F
Sbjct:  103 PVKQIRVRALYTYTGQHQDDLPFRKGDTM-FVSDVSAQWWLARHQKTGATGYIPSNYVLIDDGLPTSLDAWYDISRREADKRLLRVGNPKGTYLIRSSSETQNYALSVRHYDQERNIYVVKHYRIRVLDNDNG-YFISNRITFPNIKDLISYYSRTAEGLC-CRLTVPCPRDYRPPVQFRDFEVNRNSITMVRQLGHGSFGEVYLAKWNDSVEVAVK-MRLSHTDRTKFIEEARLMHEFHHPRIVQLLGVCTQPEDEPVYIITELMAKGALVDFLRGDEGQQLSLSDLIDMMAQIASGMTYLEERNSVHRDLRAANILVDSDNSVKVSDFGLAKIISDDAQADHSTKFPIKWTAPEAALQHIFSIKSDVWSFGVLMYEIVTYGGTPYPGMSTRQTIVEVDKGYRLPNPHT--ANHPCPDDLYNIMLKCWDVRPENRPTFRSLYDVF 542
[Close]
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A074ZSJ9 (Tyrosine-protein kinase OS=Opisthorchis viverrini OX=6198 GN=T265_04412 PE=3 SV=1)

HSP 1 Score: 393.275 bits (1009), Expect = 2.704e-127
Identity = 193/446 (43.27%), Postives = 285/446 (63.90%), Query Frame = 3 
Query:  168 PFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            P     V+A Y Y    + D+ F   + M  V+++   W      ++   G IPS+YV   DG   S+D W DI R EA+K L+++G  KGTY+IR S +  ++ALSVR   +   I+ V+H++I++ ++     +IS    F +I  +I ++ +T  G    RL  P P +Y+PP+ F+D E+NR+++ M+ ++GHG FG VY AKW  + EVAVK M  + ++R  F++EA++MH+  H +IV+LLG+C++P++ P+ II E M  G+L  +L  D+ + L LS ++ MMA IA GM+YLE +N VHRDLRA NILVD D +VKV+DFGL +   DD     +T+FP KWTAPEAA   IF+ KSD+WSFGV+MYE+VT+G  PYP +   + I  +  GYR+PNP T   +  CP+ +Y IM++CW+ +PE RP+F  L D F
Sbjct:  103 PVKQIRVRALYTYTGQHQDDLPFRKGDTM-FVSDVSAQWWLARHQKTGATGYIPSNYVLIDDGLPTSLDAWYDISRREADKRLLRVGNPKGTYLIRSSSETQNYALSVRHYDQERNIYVVKHYRIRVLDNDNG-YFISNRITFPNIKDLISYYSRTAEGLC-CRLTVPCPRDYRPPVQFRDFEVNRNSITMVRQLGHGSFGEVYLAKWNDSVEVAVK-MRLSHTDRTKFIEEARLMHEFHHPRIVQLLGVCTQPEDEPVYIITELMAKGALVDFLRGDEGQQLSLSDLIDMMAQIASGMTYLEERNSVHRDLRAANILVDSDNSVKVSDFGLAKIISDDAQADHSTKFPIKWTAPEAALQHIFSIKSDVWSFGVLMYEIVTYGGTPYPGMSTRQTIVEVDKGYRLPNPHT--ANHPCPDDLYNIMLKCWDVRPENRPTFRSLYDVF 542
[Close]
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A430QHK8 (Tyrosine-protein kinase OS=Schistosoma bovis OX=6184 GN=DC041_0007532 PE=3 SV=1)

HSP 1 Score: 389.423 bits (999), Expect = 8.841e-127
Identity = 194/460 (42.17%), Postives = 288/460 (62.61%), Query Frame = 3 
Query:  126 VSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            +S      I +  +P V   V+A Y Y+   + D+SF+  +IM V++ + + W       + + G IPS+YV   DG   S+D W DI R EA++ L+ +G  KGTY+IRPS +  ++ALSVR       ++ V+H++I+I ++ G   +IS    F +I  +I ++     G    RL  P P  Y+PP+ F+D EINRD++  + ++G G FG VY AKW  + EVAVK M    ++R+ F++EA++MH   H +IV+LLG+C+EP++ P+ II E M+ G+L  +L +++   L L  ++ +MA IA GMSYLE  N VHRDLRA NILVD D +VKV+DFGL +   DD +   NT+FP KWTAPEAA   IF+ KSD+WSFG++MYE+VT+G  PYP +   + +  +  GYR+P P T   +  CP+ +Y +M +CW+ +PE RP+F  L D F
Sbjct:   15 ISTVSPGGIGVQARPLVQ--VRALYSYQGHNQDDLSFQKGDIMFVISGMSDAWWFARHSDTGMSGYIPSNYVCLNDGLPTSLDAWYDIGRREADRKLLLVGNPKGTYLIRPSSETQNYALSVRHYDSEKNMWVVKHYRIRILDNNGG-FFISIRTTFPNIQDLINYYTVHPDGLC-CRLSIPCPRAYRPPVQFRDFEINRDSITRIRKLGQGTFGEVYLAKWNGSVEVAVK-MRLDPTDRSRFIEEARLMHAFHHPRIVQLLGVCTEPEDQPVYIITELMRKGALYDFLRTEEGHKLTLDDLIDIMAQIASGMSYLEEMNSVHRDLRAANILVDQDYSVKVSDFGLAKIISDDSHADPNTKFPIKWTAPEAALQHIFSIKSDVWSFGILMYEIVTYGGTPYPGMTTRQTVAEVEKGYRLPCPHT--PEHPCPDDLYNLMRKCWDARPENRPTFRSLYDVF 467
[Close]
BLAST of Tyrosine-protein kinase vs. TrEMBL
Match: A0A5K3ET40 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 390.963 bits (1003), Expect = 3.262e-126
Identity = 194/441 (43.99%), Postives = 281/441 (63.72%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNT-RFPFKWTAPEAA-KSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            V A Y Y A    D+SF+  ++M V   + E W      ++   G IPS+YVS ++G    +D W DI R +A+++L+  GL +GTYIIRPS    S+ALS+R       ++ ++H++I+  ++ G   YI+    F ++  +I  ++    G     L  P P  Y+PP+ F+DIE NR ++  + E+G G FG VYRA+W + ++VAVK   +T ++R +F++EAK+MHKL HR+IV LLG+C+EP E P+ II E ++ G+L+++L+S + R L LS ++ M+A IAEGM+YLE  N VHRDLRA NILVD D +VKVADFGL +  D    V    +FP KWTAPEAA    +F+ KSD+WSFGV+MYE+VT+G  PYP       +  +  GYRMPNP T  +   CP+ +Y IM++CW+ +PE RP+F  L D F
Sbjct:  117 VHALYTYVAQNADDLSFQKGDVMLVQAGLSEAWWMARHLRTGQHGYIPSNYVSVENGLLTQMDAWYDITRKDADRMLLMPGLPQGTYIIRPSSDSRSYALSIR-FQTEKNMYAIKHYKIRTRDN-GAGFYITNRTNFATVADLISHYQSINDGLC-CALTQPCPRKYKPPVQFRDIEANRKSLEFICELGKGSFGEVYRARWNKTFDVAVKQRLAT-TDRALFIEEAKVMHKLHHRRIVRLLGVCTEPPEEPVFIITELLEKGALRNFLDSAEGRQLVLSDLIDMIAQIAEGMAYLEEMNFVHRDLRAANILVDRDNSVKVADFGLAKMLDSNTPVGGVIKFPIKWTAPEAALPDHLFSIKSDVWSFGVLMYEIVTYGGTPYPRFTNRETVQQVERGYRMPNPSTPTQ--PCPDDLYVIMLQCWSARPEDRPTFRNLYDIF 551
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: ENSAMXT00000007450.2 (YES proto-oncogene 1, Src family tyrosine kinase [Source:NCBI gene;Acc:103026537])

HSP 1 Score: 297.36 bits (760), Expect = 1.155e-93
Identity = 161/438 (36.76%), Postives = 260/438 (59.36%), Query Frame = 3 
Query:  192 AKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDI-----EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSF 1481
            A Y YEA    D+SF+  E  Q++N  + +W E     S ++G IPS+YV+  D  Q     +  + R +AE+LL++ G+++G +++R S   + +F+LS+ D  +  K   V+H++++  +S G   YI+   +F ++ S+IK +     G    RL    P   +P  H Q +     EI+RD++++  ++G GCFG V+   W  + +VAVK +         FLQEA+IM KLRH K+V+L  + S+    PI I+ EFM  GSL  +L   + ++L L ++V M A I++GM+++E  N +HRDLRA NILV  ++  K+ADFGL    +D      +  +FP KWTAPEAA    F+ KSD+WSFG+++ E+VT G++PYP ++   V++ +  GYRMP P        CP  ++++M++CW  +P++RP+F
Sbjct:  101 ALYDYEARTTDDLSFKKGERFQIINNTEGDWWEACSLSSGLQGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLQPGIQRGMFLMRESETTKGAFSLSICDW-EEDKGENVKHYKVRTLDSGG--YYITTRAQFSTLQSLIKHYTAHADGLCH-RLTGVCP-TVRP--HTQGLAKDAWEISRDSLSLEVKLGQGCFGEVWMGTWKSSTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHDKLVQLYAVVSQ---EPIYIVTEFMSKGSLLDFLKEGEGKVLKLPQLVDMAAQISDGMAFIERMNYIHRDLRAANILVTDNMVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGKFSIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVDRGYRMPCPPA------CPASLHELMLQCWRREPDERPTF 522
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: SRC (proto-oncogene tyrosine-protein kinase Src-like [Source:NCBI gene;Acc:103042998])

HSP 1 Score: 290.812 bits (743), Expect = 3.724e-91
Identity = 158/440 (35.91%), Postives = 246/440 (55.91%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLK-SPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+    D++F+  E +Q++N  + +W       +   G IPS+YV+  D  Q     +  I R ++E+LL+ +   +GT+++R S   + ++ LSV D   N K   ++H++I+  +S G   YI+   +F S+  ++  +R    G   +     P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FL+EA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  DK + L L ++V M + IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P       +CP+ ++++M+ CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTTADLTFKKGERLQILNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWFFGKITRRDSERLLLNIQNRRGTFLVRESETTKGAYCLSVLDY-DNMKGLNIKHYKIRKLDSGG--FYITSRTQFTSLQQLVLHYRTHADGLCHVLTDICPMLKPQTQGLARDAWEIPRESLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKRGTMSPEAFLEEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDKGKFLRLPQLVDMASQIAAGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQVERGYRMPCP------AECPSSMHELMLSCWRKEPEERPTFEYL 515
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: ENSAMXT00000051946.1 (pep primary_assembly:Astyanax_mexicanus-2.0:22:15135214:15165330:-1 gene:ENSAMXG00000039996.1 transcript:ENSAMXT00000051946.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 288.5 bits (737), Expect = 2.947e-90
Identity = 157/440 (35.68%), Postives = 247/440 (56.14%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLK-SPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+    D++F+  E +Q++N ++ +W       ++  G IPS+YV+  D  Q     +  I R ++E+LL+ M   KGT+++R S   + ++ LSV D   N K   ++H++    +S G   YI+   +F S+  ++  +R    G   +     P        +     EI R+++ +  ++G G F  V+   W R  +VA+K +         FL+EA++M KLRH K+V+L  + SE    PI I+ E+M  G+L  +LN D  + L L ++V M + IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL     D   +  +   FP KWT+PEAA    FT KSD+WSFG+++ EVVT G++PYP +  + V++ ++ GYRMP P       +CP+ ++++M+ CW  +PE+RP+F  L
Sbjct:   98 TFVALYDYESRTSSDLTFKKGERLQILNNMEGDWWLARSLTTEESGYIPSNYVAPSDSVQAEEWFFGKITRRDSERLLLNMQNRKGTFLVRESETTKGAYCLSVLD-HDNMKGLNIKHYKFHKLDSGG--FYITSRTQFTSLQQLVLHYRAHADGLCHVLTDICPMLKPQTQGLARDAWEIPRESLRLDVKLGQGSFAEVWMGTWNRTTQVAIKTLKRGTMSPEAFLEEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGNLLDFLNGDNGKSLRLPQLVDMASQIAAGMAYMERMNYVHRDLRAANILVGDNLVCKVADFGLARLIKDNEYMAGQGATFPIKWTSPEAALYGRFTVKSDVWSFGILLTEVVTKGRVPYPGMTKSEVLEEVVQGYRMPCP------AECPSSMHELMLSCWQKEPEERPTFEYL 525
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:103038924])

HSP 1 Score: 286.574 bits (732), Expect = 1.313e-89
Identity = 163/449 (36.30%), Postives = 244/449 (54.34%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKS-------VDGW--QDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLK-SPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+    D+SF   E +Q+VN  + +W       +   G IPS+YV+  D  Q            W    I R ++E+LL+ +   +GT+++R S   + ++ LSV D   N K   V+H++I+  +S G   YI+   +F ++  ++  +RK   G         P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  D  ++L L ++V M + IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFGV++ E+ T G++PYP ++   V+D +  GYRMP P       +CP+ ++ +M+ CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTASDLSFRKGERLQIVNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEDHLRLTLEKRWYFGKITRRDSERLLLSLDNRRGTFLVRESETTKGAYCLSVLDF-DNVKGLNVKHYKIRKLDSGG--FYITSRTQFSNLQQLVSHYRKHADGLCHFLTDVCPVLKPQTQGLARDAWEIPRESLRLDLKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKILRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELATKGRVPYPGMVNREVLDQVERGYRMPCP------AECPDSLHDLMLTCWRKEPEERPTFEYL 524
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:103038924])

HSP 1 Score: 286.189 bits (731), Expect = 1.760e-89
Identity = 162/446 (36.32%), Postives = 244/446 (54.71%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEI------DENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLK-SPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+    D+SF   E +Q+VN        + +W       +   G IPS+YV+  D  Q     +  I R ++E+LL+ +   +GT+++R S   + ++ LSV D   N K   V+H++I+  +S G   YI+   +F ++  ++  +RK   G         P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  D  ++L L ++V M + IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFGV++ E+ T G++PYP ++   V+D +  GYRMP P       +CP+ ++ +M+ CW  +PE+RP+F  L
Sbjct:   88 TFVALYDYESRTASDLSFRKGERLQIVNNTRKLNCREGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLSLDNRRGTFLVRESETTKGAYCLSVLDF-DNVKGLNVKHYKIRKLDSGG--FYITSRTQFSNLQQLVSHYRKHADGLCHFLTDVCPVLKPQTQGLARDAWEIPRESLRLDLKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMGQGSLLDFLKGDMGKILRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELATKGRVPYPGMVNREVLDQVERGYRMPCP------AECPDSLHDLMLTCWRKEPEERPTFEYL 521
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: clul1 (clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GENE-031118-57])

HSP 1 Score: 281.952 bits (720), Expect = 2.533e-89
Identity = 166/467 (35.55%), Postives = 255/467 (54.60%), Query Frame = 3 
Query:  126 VSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDE--------NWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            VS  QR  +      FV     A Y Y+A  + D+SF   E  Q++N   E        +W E     +  KG IPS+YV+  D  Q     +  + R +AE+ L+  G  +GT++IR S   + +++LS+RD     K   V+H++I+  ++ G   YI+   +F ++  +++ + +   G   ++ L  P        +     E+ RD++ +  ++G GCFG V+   W    +VA+K +         FL+EA+IM KLRH K+V+L  + SE    PI I+ EFM  GSL  +L     R L L ++V M A IA GM+Y+E  N +HRDLRA NILV  +L  K+ADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+VT G++PYP ++   V++ +  GYRMP P +      CP  ++++M++CW   PE+RP+F  L
Sbjct:    3 VSSPQRTHLTGGVTLFV-----ALYDYDARTQDDLSFRKGEKFQIINNTIEVAVVYREGDWWEARSLSTGNKGYIPSNYVAPADSVQAEEWYFGKVSRKDAERQLLCPGNPRGTFLIRESETTKGAYSLSIRDW-DEVKGDNVKHYKIRKLDNGG--YYITTRAQFDTLQKLVQHYSEHADGLCYKLTLVCPNEKPQTQGLARDAWEMPRDSLKLELKLGQGCFGEVWAGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSE---EPIYIVTEFMSKGSLLDFLKEGDGRYLKLPQLVDMAAQIAAGMAYIERMNYIHRDLRAANILVGDNLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAAMFGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPPS------CPESLHELMMQCWKKDPEERPTFEYL 452
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72])

HSP 1 Score: 274.633 bits (701), Expect = 8.313e-87
Identity = 158/439 (35.99%), Postives = 245/439 (55.81%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDL-CKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            V A Y +E +   D+ F+  + M+++ E  E W+  +   S  KG IPS+YV+K +  +     +  + R E E+LL+  G   G Y++R S   + S++LSVRD    N  +  VRH++I+  ++ G   +IS    F  + ++I+ +     G  +  L+       Q        EI RD++ +   +G G FG V+   +    +VA+K M         FL EA +M  L+H ++V L  + ++    PI I+ EFM+NGSL  YL S +   L + KM+ M A IAEGM+++E KN +HRDLRA NILV+  L  K+ADFGL    +D      +  +FP KWTAPEA     F+ KSD+WSFG+++ E++T+G++PYP +  + VI  L  GYRMP PE      + P  +Y +M++CW ++PE+RP+F  L
Sbjct:    3 VVALYDFEQLNPDDMGFKKGDKMRIIQERGEWWMAELMDGSH-KGYIPSNYVAKANSLETEEWFFSGVSRKEGERLLLAPGNSIGAYLLRDSESNKGSYSLSVRDYDITNGDV--VRHYKIRTLDNGG--YFISARLTFPDLFALIQHYTAHSDGLCQKLLRPCVSKKPQQLWEKDAWEIPRDSLKLSKRLGAGQFGEVWMGIYNNRTKVAIKTMKPGSMSPEAFLDEANLMKTLQHPRLVRLYAVVTQ---EPIYIVTEFMENGSLLDYLKSTEGSTLPMPKMIDMAAQIAEGMAFIERKNYIHRDLRAANILVNEQLASKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEIITFGRIPYPGMSNSDVIRQLERGYRMPCPE------QAPKQLYGVMMDCWKERPEERPTFEYL 427
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: frk (fyn-related Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-110411-7])

HSP 1 Score: 268.085 bits (684), Expect = 3.311e-84
Identity = 158/459 (34.42%), Postives = 249/459 (54.25%), Query Frame = 3 
Query:  192 AKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQI-------KGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSR-KENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPP---IHFQDI---EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-----FKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL---LDRF 1502
            A Y Y+     D+SF+  E+++V ++ + +W    K  +         +G IP++YV++          + DI+R +AEK L+      G ++IR S  ++  ++LSVRD         V+H++I+  +  G   +IS    F ++  ++++++    G   + L+ P      P    + +  +   EI R ++ +   +G G FG V++  W  +  VAVK +     ++  F+ EA+IM +LRH  +++L  +CS  QE PI II E M++GSL  YL     + L   ++V M   IA GM+YLES+N +HRDL A NILV      KVADFGL       ++D+       + P KWTAPEA     F+ KSD+WSFG+++YE++T+G+MPYP++    V+  L  GYRMP P+       CP + Y IM+ECWN K E+RP+F  L   LD F
Sbjct:    3 ALYDYDGRTNEDLSFKEGELLEVTDKTNSDWWYAQKKTASTSNERYNTRGYIPANYVAEYQSLDAEPWFFGDIKRADAEKYLLADVNTTGAFLIRQSESRKTDYSLSVRDGST------VKHYRIRQLDENGG-FFISRRVTFQNLIELVQYYKSNSDGLC-MALQKPCVVIEAPTTIGLSYNTVDKWEIPRASIQLQKRLGAGMFGEVWQGLWNNSTLVAVKTLKPGAMKKEEFIGEAQIMKQLRHANLIQLYAVCS--QEEPIYIITELMRHGSLLDYLRGPLGKQLKAPELVDMARQIAAGMAYLESQNYIHRDLAARNILVGEGKVCKVADFGLARIIKVRYEDEYEGKAGAKVPIKWTAPEAVNFHRFSVKSDVWSFGILLYELITYGRMPYPEMGNMEVLKQLDRGYRMPQPDN------CPPLFYSIMLECWNKKEEERPTFETLQWRLDYF 445
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: hck (HCK proto-oncogene, Src family tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-090313-72])

HSP 1 Score: 265.774 bits (678), Expect = 1.085e-82
Identity = 152/438 (34.70%), Postives = 246/438 (56.16%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSR-KENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            V A Y Y+ +   D+ F   + + +V E   +W +     ++ +G IPS++V+K +  +K    ++ + R +AE+ L+  G + G+Y+IR S   + S++LSVRD         V+H++I+  +  G   +I+    F+++  ++ ++     G  +   K       Q P      EI R+++ +  ++G G FG V+   + +  +VAVK+M         FL+EA +M  L+H K+V L  + ++    PI I+ E+M+ GSL  +L + +   L   KM+ M A +AEGM+++E KN +HRDLRA NILV+++L  K+ADFGL    +D      +  +FP KWTAPEA     F+ KSD+WSFG+++ E+VT+G++PYP +    VI  L  GYRMP P+       CP  +Y IM ECW  KPE+RP+F  L
Sbjct:   68 VVALYDYDPIHADDLCFRRGDQLVIVEE-GNDWWKARSVATKKEGYIPSNFVAKVNSIEKEEWFFKGLSRKDAERQLLLCGNKIGSYLIRDSETNKGSYSLSVRDHIVEVGD-TVKHYKIRTLDKGG--YFITSRITFHTLQELVVYYHLKADGLCQKLGKPCIAIQPQKPWEKDAWEIPRESIKLEKKLGAGQFGDVWMGVYNKKTKVAVKMMKPGSMAPQAFLEEANLMKTLQHDKLVRLHAVVTD---EPIFIVTEYMEKGSLLDFLKTSEGSRLKQPKMIDMCAQVAEGMAFIEDKNYIHRDLRAANILVNVNLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFSIKSDVWSFGILLTEMVTFGRIPYPGMTNPEVIRSLERGYRMPKPDN------CPCELYSIMQECWRQKPEERPTFEYL 492
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006670.1 (pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene:ENSPMAG00000006016.1 transcript:ENSPMAT00000006670.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 255.373 bits (651), Expect = 3.790e-80
Identity = 141/371 (38.01%), Postives = 215/371 (57.95%), Query Frame = 3 
Query:  414 LMKMGLEKGTYIIRPSRKE-NSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHF--QDI----EINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEF----KDDKNEVK-NTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            LMK G   G++++R S    + ++LSVRD         V+H++I++ E KG   +I+   +F ++  +++ + +   G   + L  P      P       D+    EI R +V ++  +G G FG V++  W +   VA+K +     +R+ FL+EA++M +LRH K+++L  +C+  QE PI II E M NGSL +YL + + R LDL ++V M A +A GM+YLE++N +HRDL A NILV      KVADFGL        +D+ E +  ++FP KWTAPEAA    F+ KSD+WSFGV+++E++T+GK+PYP      V+  +  GYRMP P        CP   Y +M+ECWN   + RP+F  L
Sbjct:   10 LMKSGNVHGSFLVRQSETSGHGYSLSVRDGDT------VKHYKIRVLE-KGS-FFITRRNQFATLRDLVQSYSRDANGLC-VTLNQPCLKKEMPQTEGLSSDMADKWEIPRSSVQLVKRLGAGQFGEVWQGLWNKTTPVAIKTLKQGTMDRDDFLREAQLMKRLRHPKLIQLYAVCT--QEEPIYIITELMSNGSLANYLQTPEGRSLDLVELVDMAAQVAAGMAYLEAQNYIHRDLAARNILVAEHNACKVADFGLARVIKMSNEDEYEARVGSKFPIKWTAPEAANYNRFSIKSDVWSFGVLLHEIITYGKLPYPGQTNAEVLAAVDRGYRMPCPP------GCPQAFYDLMLECWNVDDQARPTFETL 363
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999])

HSP 1 Score: 94.7449 bits (234), Expect = 9.171e-21
Identity = 75/257 (29.18%), Postives = 130/257 (50.58%), Query Frame = 3 
Query:  741 LNEIGHGCFGSVYRA-KWGRAYEVAVKVMNSTKS-ERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNTRF--PFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTG--YRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLL 1493
            L +IG G  G VY A + G    VA+K MN  K  ++ + + E  +M   +H  IV    I S   +  + +I+E+M+ GSL   +      +L   ++  +  +   G+ +L SK V+HRD+++DNIL+ ++  +K+ DFG     ++ N  + T    P+ W APE    K +  K DIWS G+++ E++  G+ PY +    R + ++ T    ++  PE +   +K      + +  C   +PE R S + LL
Sbjct:  623 LVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNF--IDSYVLKGDLWVIMEYMEGGSLTDVVT---HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTPY-WMAPEVVSRKEYGPKVDIWSLGIMIIEMI-EGEPPYLNETPLRALYLIATNGTPKLKEPENLSSSLK------KFLDWCLCVEPEDRASATELL 866
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354])

HSP 1 Score: 93.9745 bits (232), Expect = 1.332e-20
Identity = 56/169 (33.14%), Postives = 89/169 (52.66%), Query Frame = 3 
Query:  858 QEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNTRFPFK----WTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVI 1352
             E  ++ +L H  IV   G   E     + I LE++  GS+   LN+      + S + +    I  G++YL  KN++HRD++  NIL+D+   VK+ DFG+++     N+ +N R   +    W +PE  K    T+K+DIWS G V+ E+ T GK P+PD    + I
Sbjct:  503 HEMNLLKELHHENIVTYYGASQEG--GNLNIFLEYVPGGSVSSMLNNYGP--FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT-GKHPFPDFSQMQAI 666
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 92.8189 bits (229), Expect = 3.655e-20
Identity = 70/250 (28.00%), Postives = 117/250 (46.80%), Query Frame = 3 
Query:  750 IGHGCFGSVYRAKWGRAYEV-AVK-VMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLL 1493
            IG G +G VY+A      +V A+K V+     E N  + E  ++  L H  IV+  G   +  E  + I+LE+  NGSL+  ++     L +     ++   +  G+ YL  + V+HRD++A NIL+  D TVK+ADFG++   +  +          W APE   ++  ++ SDIWS G  + E++T    PY ++    +       Y     +T Y        +   + +C+     KRP+   LL
Sbjct:   31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYE--LYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLL-GLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVN--SSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNP-PYHNLTDANI-------YYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLL 267
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: CLA4 (Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242])

HSP 1 Score: 92.4337 bits (228), Expect = 4.080e-20
Identity = 68/273 (24.91%), Postives = 130/273 (47.62%), Query Frame = 3 
Query:  738 MLNEIGHGCFGSVYRAKWGR--------------------AYEVAVKVMNSTKSERN-IFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYL-----NSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNTRF--PFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTG--YRMPNPETIYKDVK-------CPNIIYQIMVE 1445
            ++ + G G  GSVY A+                         +VA+K M  +K  R  + + E  +M   RH+ IV  L       +  + +++EFM+ GSL   +     N +    L   ++ +++ +  +G+ +L  K+++HRD+++DN+L+D    VK+ DFG      DK   + T    P+ W APE  K + +  K D+WS G++  E++  G+ PY +    + + ++ T    ++ +PE++  ++K       C ++ Y+   E
Sbjct:  548 VIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDD-LWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPY-WMAPEVVKQREYDEKIDVWSLGIMTIEMLE-GEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTE 817
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631])

HSP 1 Score: 92.0485 bits (227), Expect = 7.961e-20
Identity = 78/265 (29.43%), Postives = 126/265 (47.55%), Query Frame = 3 
Query:  750 IGHGCFGSVYRAKWGRAYEV-AVKVMNSTK-SERN--------IFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERL---LDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDD--KNEVKNTRFPFKWTAPEAAKSKI-FTSKSDIWSFGVVMYEVVTWGKMPYPDI-LATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLL 1493
            IG G FG+VY        E+ AVK +   K S +N            E   +  L H  IV+ LG   E + +   + LE++  GS+   +     R+    D   + H+   + +G++YL SK ++HRD++ADN+L+D D   K++DFG++    D   N     R    W APE   +K  +++K DIWS G ++ E+   GK P+ ++ +   +  I  +    P PE     +    I    +  C+   PEKRP+ + LL
Sbjct: 1181 IGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGF--ENKNNIYSLFLEYVAGGSVGSLI-----RMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFA-GKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLIS--QIGRNFLDACFEINPEKRPTANELL 1435
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO47195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN18])

HSP 1 Score: 216.468 bits (550), Expect = 3.524e-66
Identity = 115/275 (41.82%), Postives = 159/275 (57.82%), Query Frame = 3 
Query:  666 SPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYE-VAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEF--KDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSF 1481
            SP PD +         EI R  + M +++G G +G VY   W +  + VAVK +     E   FL+EA +M  ++H+ +V+LLG+C+  +E P  II EFM NG+L  YL S K + LD   +++M   +   MSYLES N +HRDL A N LV  +  VKVADFGL+    +D     +  +FP KWTAPEA     F+ KSD+W+FG++++E+ T+G  PYP I  ++V D L  GYRMP PE       CP  +Y +M  CW   P  RPSF
Sbjct:    1 SPEPDEW---------EIERTEIAMKHKLGGGQYGEVYEGTWKKYNKTVAVKTLREETMEVEEFLKEASVMKGIKHQNLVQLLGVCT--REPPFYIITEFMMNGNLLDYLRSPKGKDLDAVTLMYMATQVGSAMSYLESMNFIHRDLAARNCLVGDNNLVKVADFGLSRLVSEDIYTAHQGAKFPIKWTAPEALAHNTFSIKSDVWAFGILLWELATYGMSPYPGIDLSQVYDKLDGGYRMPCPE------GCPPEVYSLMQTCWCWDPNSRPSF 258
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO40994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5K8])

HSP 1 Score: 192.586 bits (488), Expect = 9.882e-56
Identity = 109/286 (38.11%), Postives = 161/286 (56.29%), Query Frame = 3 
Query:  675 PDNYQPP---IHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYE----VAVKVM--NSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLT-EFKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            P NY  P   +     E+++  + +   IG G FG VY+    R  E    VA+K +   ST   R  FL EA +M +     ++ L G+ S+    P++I+ EFM NGSL ++L     +L  L +++ M   IA GM YL   N VHRDL A NILV   L  KVADFGL+ E +D   E    + P +WTAPEA K + F++ SD+WS+G++++E  ++ + PY D     V+D + TGYR+P P      + CP +I+QIM+ECW+    KRPSF+ ++ + 
Sbjct:   36 PSNYNDPEEALRNFAKELDKRWLKLEKVIGGGEFGDVYKGTLKRPGENTIPVAIKTLKQGSTSKNRGDFLSEASVMGQFCDPNVIFLEGVVSKTH--PLMIVTEFMSNGSLDNFLKKMDSKL-SLIQLMGMARGIASGMKYLSEMNFVHRDLAARNILVTETLVCKVADFGLSRELEDSAYETSGGKIPVRWTAPEAIKYRKFSTSSDVWSYGILLWETFSFAERPYWDWSNFEVMDRVETGYRLPPP------MSCPKVIHQIMLECWDADRTKRPSFALIVKQL 312
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO49804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFY7])

HSP 1 Score: 185.652 bits (470), Expect = 1.675e-55
Identity = 94/225 (41.78%), Postives = 132/225 (58.67%), Query Frame = 3 
Query:  789 WGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEF--KDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWND 1457
            W     VAVK+M         F++EAK+M + +H  +V+L GICSE    PI II E MK G L HYL   + +L   ++M  M+  +A  M YLES N +HRDL A N L+  + TVKVADFGL  +   D+    + T+FP KW APE      F+SKSD+W+FG++ +EV T GK PYP    T V+ +++ GYR+  P      ++CP+  Y  M +CW++
Sbjct:    2 WRGTIPVAVKMMKDGAMSEEDFIEEAKVMKQFQHGNLVQLYGICSE---KPIYIIQELMKGGCLLHYLRKSQFKLQS-AEMTEMVRQVAAAMKYLESHNFIHRDLAARNCLIGENRTVKVADFGLARYVIDDEYTASEGTKFPIKWAAPEVILYSKFSSKSDVWAFGILAWEVYTGGKQPYPATNNTDVVQMVINGYRLEKP------LRCPDAAYSTMRKCWHE 216
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO33736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRD7])

HSP 1 Score: 190.274 bits (482), Expect = 3.890e-55
Identity = 106/292 (36.30%), Postives = 170/292 (58.22%), Query Frame = 3 
Query:  675 PDNYQPPIH-FQDI--EINRDNVNMLNEIGHGCFGSVYRAKWGR----AYEVAVKVM--NSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNE-------VKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            P NY  P+     +  EIN+D++ +   IG G F  VYR           +VAVK++   S+   R  F  EA IM +  H  ++ L G+ +  +  P++II EF++NGSL ++L S+  RL  L ++V +   +A GM+YL   N +HRDL A NILV  +L  KV+DFGL+   DD  E        +  + P +WTAPEA + + F+S SD+WS+G++++E++++G+ PY      +V+D +  GYR+P P      +KCP +I+ +M++CW+ +   RP F+ ++ RF
Sbjct:    5 PSNYGDPMEALMSVAKEINKDDLKLEIIIGGGEFADVYRGVLTNEDKTQEKVAVKILKPGSSHKNREDFCVEASIMGQFDHPNVIALKGVITRTR--PMMIITEFLENGSLDNFLKSNDGRLTTL-QLVGIGRGVAAGMAYLSEMNFIHRDLAARNILVSDNLAAKVSDFGLSRELDDSPENEQSEYQTQGGKIPVRWTAPEAIRYRKFSSASDVWSYGILLWEIMSFGERPYWTWDNFQVMDRVEGGYRLPAP------MKCPKVIHNLMLDCWDKEKTSRPKFADIVRRF 287
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Match: EDO47652 (Tyrosine-protein kinase receptor [Source:UniProtKB/TrEMBL;Acc:A7RLS3])

HSP 1 Score: 187.578 bits (475), Expect = 4.436e-55
Identity = 107/290 (36.90%), Postives = 160/290 (55.17%), Query Frame = 3 
Query:  690 PPIHFQD-IEINRDNVNMLNEIGHGCFGSVYRAKWGRAYE---------VAVKVM--NSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLL--------DLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNTR------FPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSF 1481
            P ++  D  E+ R+ + ++ E+G+G FG VY    G A +         VAVK +  N++  +R  FLQEA IM   +   +V LLG+ S+ Q  P L+++E M NG LK++L S +  +          L +M+ M  +IA+GM+YL ++  VHRDL A N +V+ +LTVK+ DFG+T    D  E    R       P +W APE+ K  +FTS SD+WSFGVVM+E+ T    PYP      V+  ++ G  MP P+       CP+ ++ +M  CW   P+ RP+F
Sbjct:    3 PSVYIADEWEVPREKIKLIRELGNGSFGMVYE---GEATDIVPNKPKCKVAVKTVSENASIRDRIEFLQEASIMKAFQCNHVVRLLGVVSDGQ--PTLVVMELMDNGDLKNFLRSHRPEVTMESDEPPPTLQQMLQMAGEIADGMAYLAARKFVHRDLAARNCMVNANLTVKIGDFGMTR---DIYETDYYRKGGKGLLPVRWMAPESLKDGVFTSPSDVWSFGVVMWEMATLASQPYPGKSNEEVLKYVVDGGVMPKPD------DCPDRLFDLMTLCWQFSPKARPTF 278
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: blk (BLK proto-oncogene, Src family tyrosine kinase [Source:NCBI gene;Acc:101163706])

HSP 1 Score: 294.664 bits (753), Expect = 1.996e-93
Identity = 169/453 (37.31%), Postives = 263/453 (58.06%), Query Frame = 3 
Query:  138 QRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGW--QDIQRWEAEKLLMKMGLEKGTYIIRPSR-KENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPF-PDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSF 1481
            QR +  L    FV     A++ ++A    D+SF+  + +++++E  E W       +  +G IPS+YV++ D  +  V+ W  +D+ R E E+LL+  G + GT++IR S   + S++LS+RD  +      V+H++I+  +  G   YIS +  F S+  ++K++ +T  G    RL SP  P + Q P    + EI RD + M  ++G G FG V+   +    +VA+K +     E   FLQEA +M +L+H ++V L  + ++    PILI+ E+M NGSL  +L SD+   L ++K++ M A IAEGM+Y+E KN +HRDLRA NILV   L  K+ADFGL    + +    +  +FP KWTAPEA     FT KSD+WSFG+++ E+VT+G++PYP +    V+  L   YRMP P+       CP  +Y IM+ CW  +PE+RP+F
Sbjct:   34 QRGNTSLDNDVFV-----AQHDFKATNGSDLSFKKGDKLKILHERGE-WCLAKSISTGDEGYIPSNYVARADSLE--VEKWFFKDVSRRETERLLLAPGNKPGTFLIRESETSKGSYSLSIRDHDQQQGDV-VKHYKIRCLDKGG--FYISPSTTFSSLSELVKYYSRTADGLCE-RLNSPCKPKDPQEPWAHDEWEIPRDTLKMTKKLGAGQFGEVWMGYYKNTQKVAIKTLKEGTMEPEAFLQEANLMKQLQHDRLVRLHAVVTK---EPILIVTEYMVNGSLLDFLKSDEGGKLKMNKLIDMSAQIAEGMAYIEKKNYIHRDLRAANILVSETLHCKIADFGLARIIETEYTAQEGAKFPIKWTAPEAINFGTFTIKSDVWSFGILLTEIVTYGRIPYPGMTNPEVVRCLDQSYRMPRPD------DCPVELYDIMMMCWRQRPEERPTF 465
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: SRC (SRC proto-oncogene, non-receptor tyrosine kinase [Source:NCBI gene;Acc:101173856])

HSP 1 Score: 296.204 bits (757), Expect = 3.399e-93
Identity = 164/441 (37.19%), Postives = 249/441 (56.46%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRK--TGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            T  A Y YE+    D++F   + +Q+VN  + +W       +   G IPS+YV+  D  Q     +  I R ++E+LL+ +   +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F S+  ++  +RK   G+ +A   +  P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  D  +LL L ++V M A IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFGV++ E+ T G++PYP ++   V+D +  GYRMP P       +CP+ ++++M+ CW   PE+RP+F  L
Sbjct:   96 TFVALYDYESRTASDLTFRKGDRLQIVNNTEGDWWLARSLTTGESGYIPSNYVAPSDSIQAEEWYFGKITRRDSERLLLNLQNRRGTFLVRESETTKGAYCLSVLDY-DNAKGLNVKHYKIRKLDSGG--FYITSRTQFTSLQQLVFHYRKHSDGLCHALTDV-CPVAKPQTQGLARDAWEIPRESLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDTGKLLRLPQLVDMAAQIAAGMAYVEKMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELATKGRVPYPGMVNREVLDQVERGYRMPCP------AECPSSLHELMLSCWRKDPEERPTFEYL 523
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: lyn (tyrosine-protein kinase Lyn [Source:NCBI gene;Acc:101167902])

HSP 1 Score: 290.041 bits (741), Expect = 3.276e-91
Identity = 168/442 (38.01%), Postives = 254/442 (57.47%), Query Frame = 3 
Query:  198 YKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSR-KENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSP-FPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTE-FKDDKNEVK-NTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSF---SCLLDRF 1502
            Y YEA+   D+ F+  E M+V+ E  E W +     +  +G IP +YV++ +  +     ++D+ R +AE+ LM    + G+Y+IR S   + S++LS+RD   N  +  V+H++I+  ++ G   +IS    F  I SM+K +     G  R +L+SP      Q P      EI++D++ M+ ++G G FG V+ A +    +VAVK +         FL+EA IM  L+H ++V L  + ++ +  PI II E+M NGSL  +L S+    L L K++   A IAEGMS++E +N +HRDLRA N+LV   L  K+ADFGL    +DD+   +   +FP KWTAPEA     FT KSD+WSFGV++YE++T+GK+PYP +    V+  +  GYRMP PE       CP  +Y+IM  CW  +PE RP+F     +LD F
Sbjct:   71 YPYEAVHSDDLGFKKGEKMKVLEERGE-WWKARSLTTNKEGFIPCNYVAQANTMETEEWFFKDLTRKDAERQLMAPANKPGSYLIRESETSKGSYSLSIRDR-DNQGMDLVKHYKIRKLDNGG--FFISPKISFNDIGSMVKHYHSKADGLCR-KLESPCVKPKAQKPWAKDAWEISKDSIKMVKKLGAGQFGEVWMAYYNNTTKVAVKTLKPGTMTVEAFLEEANIMKTLQHERLVRLYAVVTKTE--PIYIITEYMANGSLLDFLKSEVGGKLQLPKLIDFSAQIAEGMSFIEKRNYIHRDLRAANVLVSESLLCKIADFGLARVIEDDEYSAREGAKFPIKWTAPEAINYGSFTIKSDMWSFGVLLYEIITFGKIPYPGMTKGEVVSSIQRGYRMPRPEN------CPTQLYEIMTSCWKFRPEDRPTFEYMQSVLDDF 499
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: src (proto-oncogene tyrosine-protein kinase Src [Source:NCBI gene;Acc:101164480])

HSP 1 Score: 285.419 bits (729), Expect = 3.698e-89
Identity = 166/471 (35.24%), Postives = 253/471 (53.72%), Query Frame = 3 
Query:  117 NKIVSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVD---------GWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNAR-IRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            N IVS + R ++      FV     A Y YE+    D+SF   E +Q+VN  + +W       +   G IPS+YV+  +  Q   D          +  I R ++E+LL+ +   +GT+++R S   + ++ LSV D   N+K   V+H++I+  +S G   YI+   +F  +  ++  +RK   G    +    P        +     EI R+++ +  ++G GCFG V+   W     VA+K +         FLQEA++M KLRH K+V+L  + SE    PI I+ E+M  GSL  +L  D  ++L L ++V M + IA GM+Y+E  N VHRDLRA NILV  +L  KVADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+ T G++PYP ++   V+D +  GYRMP P        CP  ++++M+ CW  + E+RP+F  L
Sbjct:   71 NNIVSSSTRITLAGGVTTFV-----ALYDYESRTASDLSFRKGERLQIVNNTEGDWWLARSLATGESGYIPSNYVAPSESIQAEDDLKLTLDSRWYFGKITRRDSERLLLSLENRRGTFLVRESETTKGAYCLSVLDY-DNTKGLNVKHYKIRKLDSGG--FYITSRTQFSGLQPLVNHYRKHADGLCHSLTDICPVLKPQTQGLAKDAWEIPRESLRLDVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSE---EPIYIVTEYMSQGSLLDFLKGDMGKMLRLPQLVDMASQIASGMAYVERMNYVHRDLRAANILVGDNLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELATKGRVPYPGMVNREVLDQVDRGYRMPCP------ADCPESLHELMLTCWRKEAEERPTFEYL 524
[Close]
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Match: YES1 (YES proto-oncogene 1, Src family tyrosine kinase [Source:NCBI gene;Acc:101158313])

HSP 1 Score: 285.419 bits (729), Expect = 4.172e-89
Identity = 156/437 (35.70%), Postives = 252/437 (57.67%), Query Frame = 3 
Query:  192 AKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRK-ENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNA-RIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEV--KNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCL 1490
            A Y YEA    D++F+  +  Q++N  + +W E     +  KG IPS+YV+  D  Q     +  + R +AE+LL+  G ++GT+++R S   + +++LS+RD   ++K   V+H++I+  ++ G   YI+   +F ++  ++K + +   G   R+    P        +     EI+R+++ +  ++G GCFG V+   W    +VA+K +         FLQEA+IM KLRH K+V L  + SE    PI I+ E+M  GSL  +L   + + L+L  +V M A IA+GM+++E  N +HRDLRA NILV  +L  K+ADFGL    +D      +  +FP KWTAPEAA    FT KSD+WSFG+++ E+VT G++PYP ++   V++ +  GYRMP P+       CP  ++++M  CW  +P++RP+F  L
Sbjct:  105 ALYDYEARTSDDLTFKKGDRFQIINNTEGDWWEARSITTGKKGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNDRGTFLVRESETTKGAYSLSIRDW-DSAKGDNVKHYKIRKLDNGG--YYITTRAQFDTLQKLVKHYTEHADGLCHRLTTVCPTVKPQTQGLAKDAWEISRESLQLELKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLQEAQIMKKLRHDKLVPLFAVVSE---EPIYIVTEYMSKGSLLDFLKEGEGKFLNLVMLVDMAAKIADGMAFIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQ------GCPESLHEMMKLCWKKEPDERPTFEYL 529
[Close]
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000077919.1 (SMESG000077919.1)

HSP 1 Score: 990.719 bits (2560), Expect = 0.000e+0
Identity = 492/495 (99.39%), Postives = 494/495 (99.80%), Query Frame = 3 
Query:   72 MGQTQSSENLRKSSRNKIVSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRFXXXXXXXXXXXXFNGFDK 1556
            MGQTQSSENLRKSSRNKIVSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGK+LYISGNQKFYSIPSMIKFF+KTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWN KPEKRPSFSCLLDRFDSIIVDDISKVDFNGFDK
Sbjct:    1 MGQTQSSENLRKSSRNKIVSKNQRNSIELLKKPFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKLLYISGNQKFYSIPSMIKFFQKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNGKPEKRPSFSCLLDRFDSIIVDDISKVDFNGFDK 495
[Close]
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000072548.1 (SMESG000072548.1)

HSP 1 Score: 607.06 bits (1564), Expect = 0.000e+0
Identity = 285/448 (63.62%), Postives = 354/448 (79.02%), Query Frame = 3 
Query:  168 PFVHYTVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDDKN---EVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            P   Y VKAKYKY A  E DISFE  E+M V+   DE+WL V    S+++GL+P++YVSKQDGS +SV+ W++IQRWEAEKLLM++GL+KGTYIIRPSRKEN FALSVRD  +  KIF V+HFQIK++      LY    + F  I ++I+F+ K GIGN+ + L  P PDNYQPPIHFQDIEINR+N+ +LNEIG GCFGSV++AKWGRAYEVA K++ STK+ER  FLQEAKIMHKLRHRKIVELLG+C+EPQ+ P++II+EFMK GSLK YL SD+ +  +LS+M+HMMA+I+EGM+YLES+ VVHRDLRADNILV  DLTVKVADFGLTE  +  N   E KN RFP+KWTAPEAAKSK+FTSKSD+WSFG+VMYE++TW   PYPD  A  VID + +GYRMPNPET    V CP+ IY+IM++CW+  P +RP+F+ L ++ 
Sbjct:   30 PPGSYMVKAKYKYTATAETDISFEDKEVMFVLEVFDEHWLRVELKNSKLQGLVPANYVSKQDGSPQSVEAWREIQRWEAEKLLMRVGLQKGTYIIRPSRKENCFALSVRDFDEKKKIFLVKHFQIKVNIEDKNTLYSINVRGFPDILTLIQFYEKNGIGNSHVPLTDPLPDNYQPPIHFQDIEINRENIEILNEIGRGCFGSVHKAKWGRAYEVAAKMLQSTKAEREKFLQEAKIMHKLRHRKIVELLGVCTEPQDMPMIIIVEFMKFGSLKEYLKSDEGKKTNLSQMIHMMAEISEGMAYLESEKVVHRDLRADNILVADDLTVKVADFGLTEITEGANENQEKKNLRFPYKWTAPEAAKSKVFTSKSDVWSFGIVMYEILTWSNPPYPDTPAKEVIDKVSSGYRMPNPETFIPGVHCPDEIYKIMIDCWHADPAQRPTFASLQEQL 477
[Close]
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000072546.1 (SMESG000072546.1)

HSP 1 Score: 415.231 bits (1066), Expect = 2.544e-140
Identity = 199/435 (45.75%), Postives = 300/435 (68.97%), Query Frame = 3 
Query:  186 VKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDD--KNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFS 1484
            V A+YKY+A+  +DISF+ NE+M VV E D+ W EV+K + + +GL+PS+YV KQDGS +SV+GW  I+RWEAEKLLM   +   TY+IRPS+K+  + +S++     +K + V+HF I++ + K KV+Y +G   F     +I+ F+K GIG   + + +PF +   PPIH  ++ I ++++ +++EIG   +G V RA WG++Y V  K ++ + S+R  F+ E  + +KLRH++IVE+LGIC+EP+ SPI++I E+++NGSLK +L S +   L+L  M    A+I+EGM+YLE K +VH +L+++NILVD D++VK++DFGL    D+  K+E  +     KW APE A   IFTSKSD+WSFG+V++E++TW K PYP I A  V+  ++ GYRM NP+  +  V CP  IY +MV CW++KPE RP+FS
Sbjct:   29 VIAQYKYDAIGSMDISFQQNEVMVVVKEFDQFWYEVIKMKDKTRGLVPSNYVMKQDGSPQSVEGWWYIERWEAEKLLMNPDVTNETYLIRPSKKKRDYIISLKKQDNYTKEYNVKHFIIRVIKEKNKVIYFNGLSTFSDFGMIIEHFKKHGIGKKNLPINNPFVNVRAPPIHSVNMIIKKEHIQIVSEIGKTSYGIVNRAIWGKSYIVTAKSLSISSSKRQQFIDEVLLFNKLRHKRIVEVLGICTEPKHSPIILICEYLQNGSLKDFLKSARGAKLNLLDMTERFAEISEGMAYLERKGLVHCNLKSENILVDYDMSVKISDFGLRRMIDEQLKDEEDD-----KWLAPEVATDHIFTSKSDVWSFGIVLFEILTWCKAPYPGIPANEVMQKVIAGYRMENPQCYFPGVCCPCEIYNLMVRCWDNKPELRPTFS 458
[Close]
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000045588.1 (SMESG000045588.1)

HSP 1 Score: 399.823 bits (1026), Expect = 7.350e-134
Identity = 199/441 (45.12%), Postives = 283/441 (64.17%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDD-KNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            TV+A + YEA    D+ F   ++M + +++ E W   +   ++  G IPS+YV   DGS  S +GW DI   EA+K L++MG   GTYIIRP      +ALSVR        + V+H++I+  ++     YIS   KF +I S+IK++ +T       +L    P  ++PPI F+DIE++RD + +   +G+G FG VY  KW  + EVAVK +     +R+ F+ EA++MHKL H +IV++LG+C++P E P+ II E M NG+L +YL S + + L L++M+ MM+ IAEGM+YLES+N VHRDLRA NILVD DL+VKVADFGL    DD  N    T+FP KWTAPEA   + F+ KSD+WSFGV+MYE+VT+G+ PYP I   +V+D +  GYR+PNP      + CP+ +Y I ++CW+  PE RP+FS L D F
Sbjct:   68 TVRALFSYEARHTDDLEFSKGDLMYISSDMSEAWWLALHATTKKTGYIPSNYVVLDDGSPSSHEGWYDITHKEADKKLLRMGNPIGTYIIRPCSDSKHYALSVRHFDTTKNYYVVKHYKIRTLDNNLG-FYISNRSKFPNISSLIKYY-QTNTDGLCCKLTLSCPQRHKPPIQFKDIEVSRDCIRLERVLGNGSFGEVYLGKWNNSVEVAVKQLKPNSMDRSRFIAEAELMHKLNHPRIVQILGVCTQPPEQPVFIITELMANGALLNYLRSPEGQKLRLNEMLDMMSQIAEGMAYLESRNFVHRDLRAANILVDEDLSVKVADFGLARVTDDVYNADTGTKFPIKWTAPEAGMQRRFSVKSDVWSFGVLMYEIVTYGRTPYPGIPNRQVLDEVSKGYRLPNPAG--GKIVCPDELYAIKLKCWDAYPENRPTFSHLQDIF 504
[Close]
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Match: SMESG000029204.1 (SMESG000029204.1)

HSP 1 Score: 399.823 bits (1026), Expect = 7.350e-134
Identity = 199/441 (45.12%), Postives = 283/441 (64.17%), Query Frame = 3 
Query:  183 TVKAKYKYEAMREVDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSVDGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIFRVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSPFPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKVMNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKNGSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNILVDLDLTVKVADFGLTEFKDD-KNEVKNTRFPFKWTAPEAAKSKIFTSKSDIWSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPNIIYQIMVECWNDKPEKRPSFSCLLDRF 1502
            TV+A + YEA    D+ F   ++M + +++ E W   +   ++  G IPS+YV   DGS  S +GW DI   EA+K L++MG   GTYIIRP      +ALSVR        + V+H++I+  ++     YIS   KF +I S+IK++ +T       +L    P  ++PPI F+DIE++RD + +   +G+G FG VY  KW  + EVAVK +     +R+ F+ EA++MHKL H +IV++LG+C++P E P+ II E M NG+L +YL S + + L L++M+ MM+ IAEGM+YLES+N VHRDLRA NILVD DL+VKVADFGL    DD  N    T+FP KWTAPEA   + F+ KSD+WSFGV+MYE+VT+G+ PYP I   +V+D +  GYR+PNP      + CP+ +Y I ++CW+  PE RP+FS L D F
Sbjct:   68 TVRALFSYEARHTDDLEFSKGDLMYISSDMSEAWWLALHATTKKTGYIPSNYVVLDDGSPSSHEGWYDITHKEADKKLLRMGNPIGTYIIRPCSDSKHYALSVRHFDTTKNYYVVKHYKIRTLDNNLG-FYISNRSKFPNISSLIKYY-QTNTDGLCCKLTLSCPQRHKPPIQFKDIEVSRDCIRLERVLGNGSFGEVYLGKWNNSVEVAVKQLKPNSMDRSRFIAEAELMHKLNHPRIVQILGVCTQPPEQPVFIITELMANGALLNYLRSPEGQKLRLNEMLDMMSQIAEGMAYLESRNFVHRDLRAANILVDEDLSVKVADFGLARVTDDVYNADTGTKFPIKWTAPEAGMQRRFSVKSDVWSFGVLMYEIVTYGRTPYPGIPNRQVLDEVSKGYRLPNPAG--GKIVCPDELYAIKLKCWDAYPENRPTFSHLQDIF 504
The following BLAST results are available for this feature:
BLAST of Tyrosine-protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SRC1.777e-9437.27SRC proto-oncogene, non-receptor tyrosine kinase [... [more]
SRC1.777e-9437.27SRC proto-oncogene, non-receptor tyrosine kinase [... [more]
SRC1.777e-9437.27SRC proto-oncogene, non-receptor tyrosine kinase [... [more]
SRC7.268e-9236.77SRC proto-oncogene, non-receptor tyrosine kinase [... [more]
FRK1.117e-9036.82fyn related Src family tyrosine kinase [Source:HGN... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
src-26.452e-8432.64Tyrosine protein-kinase src-2 [Source:UniProtKB/S... [more]
src-15.023e-8234.36Tyrosine protein-kinase src-1 [Source:UniProtKB/S... [more]
src-12.698e-8134.36Tyrosine protein-kinase src-1 [Source:UniProtKB/S... [more]
src-12.698e-8134.36Tyrosine protein-kinase src-1 [Source:UniProtKB/S... [more]
src-13.536e-8134.36Tyrosine protein-kinase src-1 [Source:UniProtKB/S... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Src64B1.983e-9235.78gene:FBgn0262733 transcript:FBtr0100508[more]
Src64B1.983e-9235.78gene:FBgn0262733 transcript:FBtr0100505[more]
Src64B1.983e-9235.78gene:FBgn0262733 transcript:FBtr0100504[more]
Src64B1.983e-9235.78gene:FBgn0262733 transcript:FBtr0304990[more]
Src64B1.983e-9235.78gene:FBgn0262733 transcript:FBtr0304989[more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lyn4.622e-9338.20LYN proto-oncogene, Src family tyrosine kinase [So... [more]
src2.074e-9237.33v-src avian sarcoma (Schmidt-Ruppin A-2) viral onc... [more]
src2.074e-9237.33v-src avian sarcoma (Schmidt-Ruppin A-2) viral onc... [more]
blk1.329e-9036.88BLK proto-oncogene, Src family tyrosine kinase [So... [more]
blk1.329e-9036.88BLK proto-oncogene, Src family tyrosine kinase [So... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cthrc17.822e-9637.95collagen triple helix repeat containing 1 [Source:... [more]
cthrc11.167e-9537.95collagen triple helix repeat containing 1 [Source:... [more]
cthrc11.185e-9537.15collagen triple helix repeat containing 1 [Source:... [more]
cthrc12.185e-9537.95collagen triple helix repeat containing 1 [Source:... [more]
cthrc14.759e-9537.95collagen triple helix repeat containing 1 [Source:... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Src2.505e-9437.27Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9... [more]
Src2.505e-9437.27Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9... [more]
Src2.505e-9437.27Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9... [more]
Src1.002e-9136.77Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9... [more]
Src1.002e-9136.77Rous sarcoma oncogene [Source:MGI Symbol;Acc:MGI:9... [more]
back to top
BLAST of Tyrosine-protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P42687|SPK1_GIRTI0.000e+060.00Tyrosine-protein kinase SPK-1 OS=Girardia tigrina ... [more]
sp|P13116|SRC2_XENLA3.822e-9437.95Tyrosine-protein kinase Src-2 OS=Xenopus laevis OX... [more]
sp|P12931|SRC_HUMAN8.534e-9437.27Proto-oncogene tyrosine-protein kinase Src OS=Homo... [more]
sp|P13115|SRC1_XENLA1.223e-9337.73Tyrosine-protein kinase Src-1 OS=Xenopus laevis OX... [more]
sp|Q9WUD9|SRC_RAT1.636e-9337.27Proto-oncogene tyrosine-protein kinase Src OS=Ratt... [more]
back to top
BLAST of Tyrosine-protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G7YFZ51.914e-12743.27Tyrosine-protein kinase OS=Clonorchis sinensis OX=... [more]
A0A4S2LUM52.203e-12743.27Tyrosine-protein kinase OS=Opisthorchis felineus O... [more]
A0A074ZSJ92.704e-12743.27Tyrosine-protein kinase OS=Opisthorchis viverrini ... [more]
A0A430QHK88.841e-12742.17Tyrosine-protein kinase OS=Schistosoma bovis OX=61... [more]
A0A5K3ET403.262e-12643.99Uncharacterized protein OS=Mesocestoides corti OX=... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000007450.21.155e-9336.76YES proto-oncogene 1, Src family tyrosine kinase [... [more]
SRC3.724e-9135.91proto-oncogene tyrosine-protein kinase Src-like [S... [more]
ENSAMXT00000051946.12.947e-9035.68pep primary_assembly:Astyanax_mexicanus-2.0:22:151... [more]
src1.313e-8936.30proto-oncogene tyrosine-protein kinase Src [Source... [more]
src1.760e-8936.32proto-oncogene tyrosine-protein kinase Src [Source... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
clul12.533e-8935.55clusterin-like 1 (retinal) [Source:ZFIN;Acc:ZDB-GE... [more]
hck8.313e-8735.99HCK proto-oncogene, Src family tyrosine kinase [So... [more]
frk3.311e-8434.42fyn-related Src family tyrosine kinase [Source:ZFI... [more]
hck1.085e-8234.70HCK proto-oncogene, Src family tyrosine kinase [So... [more]
ENSPMAT00000006670.13.790e-8038.01pep scaffold:Pmarinus_7.0:GL482639:18:11990:1 gene... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
STE209.171e-2129.18Cdc42p-activated signal transducing kinase; involv... [more]
STE111.332e-2033.14Signal transducing MEK kinase; involved in pheromo... [more]
CDC153.655e-2028.00Protein kinase of the Mitotic Exit Network; locali... [more]
CLA44.080e-2024.91Cdc42p-activated signal transducing kinase; member... [more]
BCK17.961e-2029.43MAPKKK acting in the protein kinase C signaling pa... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO471953.524e-6641.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO409949.882e-5638.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO498041.675e-5541.78Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO337363.890e-5536.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO476524.436e-5536.90Tyrosine-protein kinase receptor [Source:UniProtK... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
blk1.996e-9337.31BLK proto-oncogene, Src family tyrosine kinase [So... [more]
SRC3.399e-9337.19SRC proto-oncogene, non-receptor tyrosine kinase [... [more]
lyn3.276e-9138.01tyrosine-protein kinase Lyn [Source:NCBI gene;Acc:... [more]
src3.698e-8935.24proto-oncogene tyrosine-protein kinase Src [Source... [more]
YES14.172e-8935.70YES proto-oncogene 1, Src family tyrosine kinase [... [more]
back to top
BLAST of Tyrosine-protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000077919.10.000e+099.39SMESG000077919.1[more]
SMESG000072548.10.000e+063.62SMESG000072548.1[more]
SMESG000072546.12.544e-14045.75SMESG000072546.1[more]
SMESG000045588.17.350e-13445.12SMESG000045588.1[more]
SMESG000029204.17.350e-13445.12SMESG000029204.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015527 ID=SMED30015527|Name=Tyrosine-protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1660bp
TATCACAAACAGTTGAATATTTGTAAAATTAATTTCATCTCATAGTATCG
CTTTTAACATAGAGTTTTTGGATGGGACAAACCCAATCTTCTGAAAACCT
CCGAAAATCTTCTAGAAACAAGATAGTCTCCAAGAACCAAAGAAATTCAA
TAGAATTATTAAAAAAACCCTTTGTCCATTATACAGTAAAAGCCAAATAT
AAATACGAAGCCATGAGAGAAGTGGATATTTCTTTCGAAATTAACGAAAT
TATGCAAGTTGTCAATGAAATTGATGAAAACTGGTTGGAGGTAGTCAAAC
CGCAGAGTCAAATAAAAGGACTTATACCATCGAGTTATGTCAGCAAACAA
GACGGAAGTCAGAAAAGTGTTGATGGTTGGCAAGATATTCAGAGATGGGA
AGCAGAAAAATTGTTAATGAAAATGGGTTTGGAAAAAGGAACCTATATTA
TAAGACCTTCAAGAAAAGAAAACAGTTTCGCCTTATCTGTAAGAGATTTA
TGTAAAAATTCCAAAATATTCAGGGTTAGGCACTTCCAGATTAAAATATC
TGAATCTAAAGGAAAAGTATTATACATTAGTGGAAATCAAAAGTTTTACA
GCATTCCATCGATGATCAAATTCTTTCGAAAGACTGGCATAGGTAATGCC
CGTATCCGATTAAAAAGTCCATTTCCGGACAATTATCAACCTCCAATTCA
TTTTCAGGATATAGAAATCAACCGGGATAATGTAAATATGCTAAATGAAA
TTGGACATGGTTGTTTTGGTTCCGTTTATCGAGCTAAATGGGGAAGAGCA
TATGAAGTGGCAGTAAAAGTCATGAATTCAACAAAATCGGAAAGAAACAT
TTTTCTTCAAGAAGCAAAAATAATGCATAAATTGCGACACAGGAAAATCG
TTGAGTTGCTTGGAATATGTTCTGAACCTCAGGAATCACCGATACTGATT
ATATTGGAATTTATGAAAAATGGTTCACTGAAACATTATTTAAATTCCGA
CAAAGAAAGATTATTGGATCTTTCAAAGATGGTTCACATGATGGCGGATA
TAGCGGAAGGAATGTCGTACCTTGAAAGTAAAAATGTTGTTCATCGGGAT
TTAAGAGCTGATAACATTTTAGTGGATTTAGACTTGACAGTTAAAGTTGC
TGATTTCGGATTAACGGAATTTAAAGATGACAAAAATGAAGTAAAAAACA
CAAGATTTCCATTTAAATGGACAGCACCAGAAGCAGCGAAGAGCAAAATA
TTTACTTCGAAATCAGATATTTGGTCATTTGGTGTGGTTATGTATGAAGT
TGTTACTTGGGGTAAAATGCCATATCCTGATATTCTTGCGACTCGAGTGA
TTGACATACTTCTAACAGGTTACAGGATGCCAAATCCGGAGACAATCTAT
AAAGATGTAAAATGTCCAAATATTATTTATCAAATTATGGTTGAATGTTG
GAATGACAAACCTGAAAAACGGCCGTCTTTTTCATGTCTTCTTGACCGAT
TTGATTCTATAATTGTCGACGACATTTCAAAAGTTGATTTTAATGGTTTT
GATAAATAATTCATAGCTACCAAAGTATGCAAAAATATTATTCGTCCGAG
TTGTTAATTTTTAATATTTATAGTATCAATAATTAATATGCGAACGAATT
TTGACTTAAT
back to top

protein sequence of SMED30015527-orf-1

>SMED30015527-orf-1 ID=SMED30015527-orf-1|Name=SMED30015527-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=496bp
MGQTQSSENLRKSSRNKIVSKNQRNSIELLKKPFVHYTVKAKYKYEAMRE
VDISFEINEIMQVVNEIDENWLEVVKPQSQIKGLIPSSYVSKQDGSQKSV
DGWQDIQRWEAEKLLMKMGLEKGTYIIRPSRKENSFALSVRDLCKNSKIF
RVRHFQIKISESKGKVLYISGNQKFYSIPSMIKFFRKTGIGNARIRLKSP
FPDNYQPPIHFQDIEINRDNVNMLNEIGHGCFGSVYRAKWGRAYEVAVKV
MNSTKSERNIFLQEAKIMHKLRHRKIVELLGICSEPQESPILIILEFMKN
GSLKHYLNSDKERLLDLSKMVHMMADIAEGMSYLESKNVVHRDLRADNIL
VDLDLTVKVADFGLTEFKDDKNEVKNTRFPFKWTAPEAAKSKIFTSKSDI
WSFGVVMYEVVTWGKMPYPDILATRVIDILLTGYRMPNPETIYKDVKCPN
IIYQIMVECWNDKPEKRPSFSCLLDRFDSIIVDDISKVDFNGFDK*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036860SH2_dom_sf
IPR036028SH3-like_dom_sf
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR001452SH3_domain
IPR000980SH2
IPR000719Prot_kinase_dom
IPR020635Tyr_kinase_cat_dom
IPR008266Tyr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR011009Kinase-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
GO:0018108peptidyl-tyrosine phosphorylation
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005515protein binding
GO:0005524ATP binding
GO:0004713protein tyrosine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
GO:0000166nucleotide binding
GO:0004715non-membrane spanning protein tyrosine kinase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 379..389
score: 63.14
coord: 295..308
score: 41.75
coord: 398..420
score: 53.95
coord: 333..351
score: 62.8
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 222..475
e-value: 5.6E-84
score: 281.5
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 221..477
e-value: 9.5E-116
score: 400.5
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 221..481
e-value: 1.7E-45
score: 167.1
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 221..481
score: 42.52
IPR000980SH2 domainSMARTSM00252SH2_5coord: 103..191
e-value: 2.4E-12
score: 57.0
IPR000980SH2 domainPFAMPF00017SH2coord: 104..185
e-value: 5.8E-11
score: 42.3
IPR000980SH2 domainPROSITEPS50001SH2coord: 106..201
score: 15.536
IPR001452SH3 domainSMARTSM00326SH3_2coord: 37..94
e-value: 4.0E-12
score: 56.3
IPR001452SH3 domainPFAMPF00018SH3_1coord: 40..87
e-value: 3.8E-8
score: 32.8
IPR001452SH3 domainPROSITEPS50002SH3coord: 34..95
score: 18.901
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 214..483
e-value: 4.3E-83
score: 280.4
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 307..495
e-value: 1.3E-45
score: 153.6
coord: 5..135
e-value: 370.0
score: -3.5
coord: 208..325
e-value: 5.1E-11
score: 39.0
NoneNo IPR availableGENE3DG3DSA:2.30.30.40coord: 23..103
e-value: 4.0E-12
score: 47.4
NoneNo IPR availablePANTHERPTHR24418TYROSINE-PROTEIN KINASEcoord: 39..482
NoneNo IPR availablePANTHERPTHR24418:SF402TYROSINE PROTEIN-KINASE SRC-1coord: 39..482
NoneNo IPR availableCDDcd00192PTKccoord: 225..478
e-value: 3.33845E-110
score: 325.648
NoneNo IPR availableCDDcd00174SH3coord: 38..89
e-value: 3.69652E-9
score: 50.5391
IPR036860SH2 domain superfamilyGENE3DG3DSA:3.30.505.10coord: 104..211
e-value: 2.0E-17
score: 65.1
IPR036860SH2 domain superfamilySUPERFAMILYSSF55550SH2 domaincoord: 103..240
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 227..249
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 339..351
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 200..475
IPR036028SH3-like domain superfamilySUPERFAMILYSSF50044SH3-domaincoord: 34..119