SMED30015457
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015457 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of SMED30015457 vs. Ensembl Human
Match: SMC1A (structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111]) HSP 1 Score: 342.813 bits (878), Expect = 4.465e-105 Identity = 192/455 (42.20%), Postives = 315/455 (69.23%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K E +EA +Y++LK E+ +++L L KL++NEVE ++ KE K +E+ + + +++++++K +K++ K REQ IE+EIK+ P++IK + H + K + +KK+ ++A++ + + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK+ E + EVE A +RI+EINKEL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 175 KEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE-------KDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 619 HSP 2 Score: 94.3597 bits (233), Expect = 1.809e-19 Identity = 51/95 (53.68%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI AERKEAK + Q +K+
Sbjct: 98 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKD 192
BLAST of SMED30015457 vs. Ensembl Human
Match: SMC1A (structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111]) HSP 1 Score: 342.428 bits (877), Expect = 7.007e-105 Identity = 192/455 (42.20%), Postives = 315/455 (69.23%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K E +EA +Y++LK E+ +++L L KL++NEVE ++ KE K +E+ + + +++++++K +K++ K REQ IE+EIK+ P++IK + H + K + +KK+ ++A++ + + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK+ E + EVE A +RI+EINKEL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 197 KEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE-------KDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 94.3597 bits (233), Expect = 1.790e-19 Identity = 51/95 (53.68%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI AERKEAK + Q +K+
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKD 214
BLAST of SMED30015457 vs. Ensembl Human
Match: SMC1B (structural maintenance of chromosomes 1B [Source:HGNC Symbol;Acc:HGNC:11112]) HSP 1 Score: 266.544 bits (680), Expect = 2.040e-90 Identity = 160/464 (34.48%), Postives = 280/464 (60.34%), Query Frame = -2
Query: 2 EKRQ-KIEIDEAAKYKKLKTELNTKRIELHLLKLFYNE--VETNEIQKEHVK-----KKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFP-GVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1366
E+RQ K+E +EA +Y+ L EL +I+L L +L++NE + + EHV K+E L HEN +K+ +K+ R+ E+E+K E P++IK + H + K +KK+ + + +Q ++++ L++++ ++ +E + + + K R++ELE +QL Y +LK++V +K + ++ L+ L E ++ +RR E+ + K+ + ++ + +KR++KL EY + + E+K+ EET+ E+E R+ E+N+EL L+ + L A ++ HE R K+ E++E+LKRL+P V GRL ++C P H+KYQ+A+TKV G+++ AIV ++K AKDCI+++K++R EPETFL LD+LD++PI+E+LR+++ +V+DVI+ + +KK +QF CGN LVC+T+E AR +A + ER+KTV+L
Sbjct: 195 ERRQAKLEKEEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENI-------VKARKKEHGMLTRQLQQTEKELKSVE-------TLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPDSVFGRLFDLCHPIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELK---GCKMVIDVIKTQFPQLKKVIQFVCGNGLVCETMEEARHIALSGPERQKTVAL 641 HSP 2 Score: 87.4261 bits (215), Expect = 2.040e-90 Identity = 47/81 (58.02%), Postives = 60/81 (74.07%), Query Frame = -1
Query: 1353 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1595
+LE+ I++KA+N LVFQGTVESI++K KER Q EEIS S E EYE K +++K EE+A N NKKKNI AER++AK
Sbjct: 120 ELEKIGIIVKAQNCLVFQGTVESISVKKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAK 200
BLAST of SMED30015457 vs. Ensembl Human
Match: SMC1B (structural maintenance of chromosomes 1B [Source:HGNC Symbol;Acc:HGNC:11112]) HSP 1 Score: 266.159 bits (679), Expect = 2.390e-90 Identity = 160/464 (34.48%), Postives = 280/464 (60.34%), Query Frame = -2
Query: 2 EKRQ-KIEIDEAAKYKKLKTELNTKRIELHLLKLFYNE--VETNEIQKEHVK-----KKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFP-GVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1366
E+RQ K+E +EA +Y+ L EL +I+L L +L++NE + + EHV K+E L HEN +K+ +K+ R+ E+E+K E P++IK + H + K +KK+ + + +Q ++++ L++++ ++ +E + + + K R++ELE +QL Y +LK++V +K + ++ L+ L E ++ +RR E+ + K+ + ++ + +KR++KL EY + + E+K+ EET+ E+E R+ E+N+EL L+ + L A ++ HE R K+ E++E+LKRL+P V GRL ++C P H+KYQ+A+TKV G+++ AIV ++K AKDCI+++K++R EPETFL LD+LD++PI+E+LR+++ +V+DVI+ + +KK +QF CGN LVC+T+E AR +A + ER+KTV+L
Sbjct: 195 ERRQAKLEKEEAERYQSLLEELKMNKIQLQLFQLYHNEKKIHLLNTKLEHVNRDLSVKRESLSHHENI-------VKARKKEHGMLTRQLQQTEKELKSVE-------TLLNQKRPQYIKAKENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEVNEELNLIRSELQNAGIDTHEGKRQQKRAEVLEHLKRLYPDSVFGRLFDLCHPIHKKYQLAVTKVFGRFITAIVVASEKVAKDCIRFLKEERAEPETFLALDYLDIKPINERLRELK---GCKMVIDVIKTQFPQLKKVIQFVCGNGLVCETMEEARHIALSGPERQKTVAL 641 HSP 2 Score: 87.4261 bits (215), Expect = 2.390e-90 Identity = 47/81 (58.02%), Postives = 60/81 (74.07%), Query Frame = -1
Query: 1353 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1595
+LE+ I++KA+N LVFQGTVESI++K KER Q EEIS S E EYE K +++K EE+A N NKKKNI AER++AK
Sbjct: 120 ELEKIGIIVKAQNCLVFQGTVESISVKKPKERTQFFEEISTSGELIGEYEEKKRKLQKAEEDAQFNFNKKKNIAAERRQAK 200
BLAST of SMED30015457 vs. Ensembl Human
Match: SMC1A (structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111]) HSP 1 Score: 94.3597 bits (233), Expect = 4.385e-21 Identity = 51/95 (53.68%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI AERKEAK + Q +K+
Sbjct: 98 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKD 192
BLAST of SMED30015457 vs. Ensembl Celegans
Match: him-1 (Structural maintenance of chromosomes protein 1 [Source:UniProtKB/Swiss-Prot;Acc:O01789]) HSP 1 Score: 194.897 bits (494), Expect = 4.422e-53 Identity = 155/477 (32.49%), Postives = 252/477 (52.83%), Query Frame = -2
Query: 2 SQNEKRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKS----HRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIE-----------EINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFP-GVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGE---RKKTVSL 1375
+Q ++ K+E DEA KY+ +K EL K L L +LF+ E +E ++E +K+ + S E R++ + +I + HRK + +E++K + + + + H K + +KK +A + N +LA L+ +E+ K+ YE + Q +++G L L Q++EY +LK + +++ + L + + K + RR+ E K KE ++ ++ L + I KE EE ++ +++ K+IE E NKEL VV L EA + E R ++ E +E LK+ FP V+GRL+++CQP+H+++ +A TK+L K+M++IVCDT++TA I Y+KD R PETFLP D L V P++EKLR+I++P V LV DVI + +KALQF CGNALVC++ E A+ +A+ GE R K VS+
Sbjct: 205 AQEKREAKMEKDEAEKYQTMKNELAAKSTMLFLHQLFHCERTIDESKEEINAQKKTIASLEATRSKEEAKIAAVHQEHRKAL-----------REVQKMTRKLDQKETDLAEKQQNMLTLKVSVAHEHKKLEIAKKMLAAAESKAENNSTQLADLKKSKKELEKKKAAYE-AEIQDMMQRGE-LNLSDEQVREYGQLKDQAQRESAMVQRELLMAEQVFEGDKSSLNHELRRQKEHQERVKAKEGDVRRIETQIATLAQRI----------KETEEETKI-LKADLKKIENDVVIDKSAAAEYNKELVAVVRQLSEASGDSAEGERNQRRTEALEGLKKNFPESVYGRLVDLCQPSHKRFNIATTKILQKHMNSIVCDTEETAAKAIVYLKDHRYPPETFLPNDALVVNPLNEKLREIKKPAGVKLVFDVINPQHQAARKALQFVCGNALVCESQEDAKQLAYGGGELKDRFKAVSM 657 HSP 2 Score: 89.3521 bits (220), Expect = 2.188e-18 Identity = 46/95 (48.42%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
++E NI +KA+NFLV+QG +E+IAMK KER Q EE+S+S EF+AEYER K E+ K E++ N+NK++ I E++EAK + Q +KN
Sbjct: 132 EMESINIFIKARNFLVYQGAIENIAMKTPKERTQLFEELSRSHEFQAEYERLKVEMTKAEDDTQHNMNKRRGIAQEKREAKMEKDEAEKYQTMKN 226
BLAST of SMED30015457 vs. Ensembl Fly
Match: SMC1 (gene:FBgn0040283 transcript:FBtr0084541) HSP 1 Score: 293.123 bits (749), Expect = 7.162e-96 Identity = 164/435 (37.70%), Postives = 269/435 (61.84%), Query Frame = -2
Query: 35 EAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAF 1339
EA +Y +L+ E N K++E L +LF+ E + + + +++E+ + E ++ DE ++ +K K R+ + I+QEI++ E P +IK +K+ H K +K E+AR+ A+Q ++ +L+ Q+ +E LK +E + S +G+++ +E +QEY +LKQ+ + + LD+++RE ++D D RR + S K+ + E+ KR KL ++I SS A+ EQ ++ +R +V ++ ++I E +ELE V LG+A+ +KHE +R KKQE++E K+ PGV+ R++ MCQP H++Y VA+TKVLGK+M+AI+ DT+KTA+ CIQ +K+Q +E ETFLPLD+L V+P+ E+LR+I +P NV LV DV++FEP I++A+ FA GNALVC+T E A VA+
Sbjct: 228 EADRYTRLQNEYNEKQVEYQLFRLFHVERDIRKFTSDLEVRQQEVKAVEQRKEAADEILREKKKDAGKITRDLAKIDQEIREFE-------TQMNKRRPLYIKAKEKVTHCKKKLISLQKTLETAREADNAHQSDIRKLEKQLADVEALKKRFEDEIENESQRRGKSVNMEEGLVQEYDRLKQEAEATATQYRSELDSVNREQKSEQDTLDGETNRRASVEESFKKLTLQREEAVKRRDKLMDHIKSSQAALEEQNRIKDELRRDVGTSKEKIAEKQRELEDVRDQLGDAKSDKHEDARRKKKQEVVELFKKQVPGVYDRMINMCQPTHKRYNVAVTKVLGKFMEAIIVDTEKTARHCIQILKEQMLEVETFLPLDYLQVKPLKERLRNISDPRNVRLVFDVLKFEPQEIERAVLFATGNALVCETPEDAMKVAY 655 HSP 2 Score: 78.5666 bits (192), Expect = 7.162e-96 Identity = 46/81 (56.79%), Postives = 53/81 (65.43%), Query Frame = -1
Query: 1350 LEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKN 1592
LE+ I +KAKNFLVFQG VE+IAMK KER EEIS S K +Y R K+E+ EEE KKK I AERKEAK+
Sbjct: 144 LEKIGINVKAKNFLVFQGAVENIAMKTPKERTALFEEISGSGLLKDDYNRLKQEMIVAEEETQFTYQKKKGIAAERKEAKH 224
BLAST of SMED30015457 vs. Ensembl Fly
Match: glu (gene:FBgn0015391 transcript:FBtr0080935) HSP 1 Score: 73.9442 bits (180), Expect = 1.918e-13 Identity = 65/236 (27.54%), Postives = 118/236 (50.00%), Query Frame = -2
Query: 2 KESELNESRKRLQKLREYIDSSNRA-------INEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQ----ELIENLKRL-----FPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 661
K++E ESRK + L+ + S ++ ++E KE+ ++ E+ S + ++++ KE + + R E +E S + Q ++++ L R+ PG+ GRL ++ KY +AI+ G+ +D IV D +TA I +K+ + TF+ LD ++ + R I P NV + D+++ E ++ A FA N LVCD +E +A+ ER + V+L
Sbjct: 515 KQAETTESRK-YETLKSSYEQSQKSLEEKVTRVDELKESIPRMKTEIASKSAEVDKMVKEERNLSMQCNKLRTEINERSSVMQAQRSNNKVLDFLMRMKMEGKIPGILGRLGDLGG-IDAKYDIAISTACGR-LDNIVTDNYETASAAIGALKEYNVGRATFITLDKIEHHRREANSR-INTPENVPRLYDLVKVEDDRVRTAFYFALRNTLVCDDLEQGTRIAYGR-ERYRVVTL 745
BLAST of SMED30015457 vs. Ensembl Zebrafish
Match: smc1al (structural maintenance of chromosomes 1A, like [Source:ZFIN;Acc:ZDB-GENE-040426-57]) HSP 1 Score: 314.694 bits (805), Expect = 1.538e-104 Identity = 178/444 (40.09%), Postives = 301/444 (67.79%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ ++L L KL++NE E ++ +E + +E+ + + ++E++K +K++ + R+Q IE+EIK+ + P +IK + H + K + ++K+ ++A++ + + ++ +L + +E + E+E + + + +G++L+LE NQ++ YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL +YI +S ++++EQK EE + EVE A +RI+EIN EL V+ LG+AR+++ E+SR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR++R LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF R KTV+L
Sbjct: 208 RYQRLKDEVVRAHVQLQLFKLYHNESEIEKLNRELAHRNKEIDKDRKRMDRVEEELKDKKKELGRMMRDQQMIEKEIKEKD-------AELNQKRPLYIKAKENTAHKIKKLEAARKSLQNAQKCYKKRKGDMDELDREQGAVEMARQEFEERMEEEAQSQGQDLQLEENQVKAYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKIETEAKIKQKIREIEENQKRIEKLEDYITTSRQSLDEQKRMEEELTEEVEQAKRRIDEINMELNQVMEQLGDARIDRQENSRQQRKAEILESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELR---GAKLVIDVIRYEPPQIKKALQYACGNALVCDNVEDARRIAFGGPYRHKTVAL 641 HSP 2 Score: 85.8853 bits (211), Expect = 1.538e-104 Identity = 44/75 (58.67%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY+R K+E+ K EE+ N ++KKNI A
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDRCKKEMVKAEEDTQFNYHRKKNIAA 194
BLAST of SMED30015457 vs. Ensembl Zebrafish
Match: smc1al (structural maintenance of chromosomes 1A, like [Source:ZFIN;Acc:ZDB-GENE-040426-57]) HSP 1 Score: 314.309 bits (804), Expect = 2.144e-104 Identity = 178/444 (40.09%), Postives = 300/444 (67.57%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ ++L L KL++NE E ++ +E + +E+ + + ++E++K +K++ + R+Q IE+EIK+ P +IK + H + K + ++K+ ++A++ + + ++ +L + +E + E+E + + + +G++L+LE NQ++ YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL +YI +S ++++EQK EE + EVE A +RI+EIN EL V+ LG+AR+++ E+SR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR++R LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF R KTV+L
Sbjct: 226 RYQRLKDEVVRAHVQLQLFKLYHNESEIEKLNRELAHRNKEIDKDRKRMDRVEEELKDKKKELGRMMRDQQMIEKEIKE-------KDAELNQKRPLYIKAKENTAHKIKKLEAARKSLQNAQKCYKKRKGDMDELDREQGAVEMARQEFEERMEEEAQSQGQDLQLEENQVKAYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKIETEAKIKQKIREIEENQKRIEKLEDYITTSRQSLDEQKRMEEELTEEVEQAKRRIDEINMELNQVMEQLGDARIDRQENSRQQRKAEILESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELR---GAKLVIDVIRYEPPQIKKALQYACGNALVCDNVEDARRIAFGGPYRHKTVAL 659 HSP 2 Score: 85.8853 bits (211), Expect = 2.144e-104 Identity = 44/75 (58.67%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY+R K+E+ K EE+ N ++KKNI A
Sbjct: 138 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDRCKKEMVKAEEDTQFNYHRKKNIAA 212
BLAST of SMED30015457 vs. Ensembl Zebrafish
Match: smc1a (structural maintenance of chromosomes 1A [Source:ZFIN;Acc:ZDB-GENE-090506-9]) HSP 1 Score: 312.383 bits (799), Expect = 3.679e-103 Identity = 176/444 (39.64%), Postives = 302/444 (68.02%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ ++L L KL++NE E ++ +E ++ E+ K + ++E++K +K++ + R+Q +E+EIK+ + P++IK + H + K + ++K+ ++A++ + + ++ +L + +E + E+E + + + +G++L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL +YI +S ++++EQ+ EE + EVE A +RI+EIN EL V+ LG+AR+++ E+SR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR++R LV+DVI++EP IKKALQ+ACGNALVC+ VE AR +AF R KTV+L
Sbjct: 208 RYQRLKDEVVRAHVQLQLFKLYHNEEEIEKLNRELSQRNREIDKDRKKMDHVEEELKDKKKELGRMMRDQQNVEKEIKEKD-------AELNQKRPQYIKAKENTAHKIKKLEVARKSLQNAQKMYKKRKADIEELDREQGAVEMSRQEFEERMEEEAQSQGQDLTLEENQVKQYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKIETEAKIKQKIREIEENQKRIEKLEDYIATSRQSLDEQRRMEEELTEEVELAKRRIDEINMELNQVMEQLGDARIDRQENSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELR---GAKLVIDVIRYEPPHIKKALQYACGNALVCENVEDARRIAFGGPYRHKTVAL 641 HSP 2 Score: 83.5741 bits (205), Expect = 3.679e-103 Identity = 43/75 (57.33%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY+R K+E+ K EE+ + ++KKNI A
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDRRKKEMVKAEEDTQFSYHRKKNIAA 194
BLAST of SMED30015457 vs. Ensembl Zebrafish
Match: smc1b (structural maintenance of chromosomes 1B [Source:ZFIN;Acc:ZDB-GENE-091217-1]) HSP 1 Score: 223.402 bits (568), Expect = 3.278e-70 Identity = 146/456 (32.02%), Postives = 264/456 (57.89%), Query Frame = -2
Query: 2 EAAKYKKLKTELNTKRIELHLLKLFYNE-------VETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFP-GVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFE--PAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1339
EA +Y+ L +L +++L L +LF+NE ++Q ++K L + E + +K+ +K+ + NRE +E+EI+ EQ P++IK H K +E+ ++ + + +EL +L+ ++ +E+ E + + +G ++L+ +QL+ Y +LK+ + L+ + L E ++ RR++EI + K ++ L + +R +KL EY++++ + + EQ++ EE + E+ R+EE+N EL V+T L AR++ E+ R K+ E++E+L+RL+P V+GRL+E+CQP H+KYQ+A+TKV GK M+AIV + A DCI+Y+K++R EPETFLP+D++DV ++E+LR+++ +V+DV+Q +K+ +Q+ CGN+LVC+T++ AR +AF+ ER +TV+L
Sbjct: 205 EAQRYQSLVDDLRECKLQLTLFQLFHNEKSIDAQSASLGDMQAAAAQQKISLDAWE-------QTVKTQKKEHGRLNRELQQLEKEIRSQEQILNQQR-------PQYIKAKVNTSHHEQKVQEAHRSLQKNQNLQAKKGQELEELKRELTELERAWKTSERQMEEEEARRGAGVQLQESQLERYKELKELARRNGAILNQSAEKLHWEVKADREKLQFDLRRKSEIQGNIKHSQTHLEDISRRAEKLEEYVNTTTQTLEEQRQQEEQLSEELAKGLVRMEEVNVELAQVLTKLQNARLDSQENRRQQKRDEVLESLRRLYPDTVYGRLVELCQPIHKKYQLAVTKVFGKNMNAIVVTSAYVAHDCIRYLKEERAEPETFLPIDYIDVPILNERLREVQ---GAKMVVDVVQCSQNAPQLKRVIQYVCGNSLVCETLKDARRIAFDGPERLQTVAL 643 HSP 2 Score: 62.7734 bits (151), Expect = 3.278e-70 Identity = 35/79 (44.30%), Postives = 51/79 (64.56%), Query Frame = -1
Query: 1359 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKE 1595
+L++ I++KAKN LV+QG VESIAM NAKER + E IS S + EY ++K +E+ + N+KK AE+K+
Sbjct: 120 ELQKIGIVVKAKNCLVYQGAVESIAMMNAKERTKMFERISGSGDLNIEYFTKLAVLQKAKEDTQFHFNRKKAATAEKKQ 198
BLAST of SMED30015457 vs. Ensembl Zebrafish
Match: smc1al (structural maintenance of chromosomes 1A, like [Source:ZFIN;Acc:ZDB-GENE-040426-57]) HSP 1 Score: 85.8853 bits (211), Expect = 1.425e-19 Identity = 44/75 (58.67%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY+R K+E+ K EE+ N ++KKNI A
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDRCKKEMVKAEEDTQFNYHRKKNIAA 194 HSP 2 Score: 30.4166 bits (67), Expect = 1.425e-19 Identity = 23/78 (29.49%), Postives = 49/78 (62.82%), Query Frame = -2
Query: 1097 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIK 1330
+Y++LK E+ ++L L KL++NE E ++ +E + +E+ + + ++E++K +K++ + R+Q IE+EIK
Sbjct: 208 RYQRLKDEVVRAHVQLQLFKLYHNESEIEKLNRELAHRNKEIDKDRKRMDRVEEELKDKKKELGRMMRDQQMIEKEIK 285
BLAST of SMED30015457 vs. Ensembl Xenopus
Match: sia1 (siamois homeodomain 1 [Source:Xenbase;Acc:XB-GENE-482368]) HSP 1 Score: 330.872 bits (847), Expect = 1.319e-108 Identity = 187/444 (42.12%), Postives = 307/444 (69.14%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ +++L L KL++NE E ++ K+ K + + + ++++E++K +K + K REQ IE+EIK+ + P++IK + H + K + +KK+ ++A++Q+ + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK EET+ EVE A +RI+EIN EL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 176 RYQRLKDEVARAQVQLQLFKLYHNESEIEKLNKDLSVKNKGIEKDKKHMDKVEEELKDKKKDLGKMMREQQAIEKEIKEKD-------AELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKQYKKRKADMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYIATSKQSLEEQKNLEETLTEEVELAKRRIDEINSELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 609 HSP 2 Score: 83.9593 bits (206), Expect = 1.319e-108 Identity = 43/75 (57.33%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI A
Sbjct: 88 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAA 162
BLAST of SMED30015457 vs. Ensembl Xenopus
Match: sia1 (siamois homeodomain 1 [Source:Xenbase;Acc:XB-GENE-482368]) HSP 1 Score: 330.487 bits (846), Expect = 1.583e-108 Identity = 187/444 (42.12%), Postives = 307/444 (69.14%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ +++L L KL++NE E ++ K+ K + + + ++++E++K +K + K REQ IE+EIK+ + P++IK + H + K + +KK+ ++A++Q+ + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK EET+ EVE A +RI+EIN EL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 208 RYQRLKDEVARAQVQLQLFKLYHNESEIEKLNKDLSVKNKGIEKDKKHMDKVEEELKDKKKDLGKMMREQQAIEKEIKEKD-------AELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKQYKKRKADMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYIATSKQSLEEQKNLEETLTEEVELAKRRIDEINSELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 83.9593 bits (206), Expect = 1.583e-108 Identity = 43/75 (57.33%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI A
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAA 194
BLAST of SMED30015457 vs. Ensembl Xenopus
Match: sia1 (siamois homeodomain 1 [Source:Xenbase;Acc:XB-GENE-482368]) HSP 1 Score: 330.487 bits (846), Expect = 1.623e-108 Identity = 187/444 (42.12%), Postives = 306/444 (68.92%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ +++L L KL++NE E ++ K+ K + + + ++++E++K +K + K REQ IE+EIK+ P++IK + H + K + +KK+ ++A++Q+ + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK EET+ EVE A +RI+EIN EL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 191 RYQRLKDEVARAQVQLQLFKLYHNESEIEKLNKDLSVKNKGIEKDKKHMDKVEEELKDKKKDLGKMMREQQAIEKEIKE-------KDAELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKQYKKRKADMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYIATSKQSLEEQKNLEETLTEEVELAKRRIDEINSELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 624 HSP 2 Score: 83.9593 bits (206), Expect = 1.623e-108 Identity = 43/75 (57.33%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI A
Sbjct: 103 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAA 177
BLAST of SMED30015457 vs. Ensembl Xenopus
Match: sia1 (siamois homeodomain 1 [Source:Xenbase;Acc:XB-GENE-482368]) HSP 1 Score: 330.487 bits (846), Expect = 1.808e-108 Identity = 187/444 (42.12%), Postives = 307/444 (69.14%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ +++L L KL++NE E ++ K+ K + + + ++++E++K +K + K REQ IE+EIK+ + P++IK + H + K + +KK+ ++A++Q+ + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK EET+ EVE A +RI+EIN EL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 208 RYQRLKDEVARAQVQLQLFKLYHNESEIEKLNKDLSVKNKGIEKDKKHMDKVEEELKDKKKDLGKMMREQQAIEKEIKEKD-------AELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKQYKKRKADMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYIATSKQSLEEQKNLEETLTEEVELAKRRIDEINSELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 83.9593 bits (206), Expect = 1.808e-108 Identity = 43/75 (57.33%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI A
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAA 194
BLAST of SMED30015457 vs. Ensembl Xenopus
Match: sia1 (siamois homeodomain 1 [Source:Xenbase;Acc:XB-GENE-482368]) HSP 1 Score: 330.487 bits (846), Expect = 2.015e-108 Identity = 187/444 (42.12%), Postives = 307/444 (69.14%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ +++L L KL++NE E ++ K+ K + + + ++++E++K +K + K REQ IE+EIK+ + P++IK + H + K + +KK+ ++A++Q+ + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK EET+ EVE A +RI+EIN EL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 208 RYQRLKDEVARAQVQLQLFKLYHNESEIEKLNKDLSVKNKGIEKDKKHMDKVEEELKDKKKDLGKMMREQQAIEKEIKEKD-------AELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKQYKKRKADMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYIATSKQSLEEQKNLEETLTEEVELAKRRIDEINSELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 83.9593 bits (206), Expect = 2.015e-108 Identity = 43/75 (57.33%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI A
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAA 194
BLAST of SMED30015457 vs. Ensembl Mouse
Match: Smc1a (structural maintenance of chromosomes 1A [Source:MGI Symbol;Acc:MGI:1344345]) HSP 1 Score: 342.813 bits (878), Expect = 4.044e-105 Identity = 192/455 (42.20%), Postives = 315/455 (69.23%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K E +EA +Y++LK E+ +++L L KL++NEVE ++ KE K +E+ + + +++++++K +K++ K REQ IE+EIK+ P++IK + H + K + +KK+ ++A++ + + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK+ E + EVE A +RI+EINKEL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 197 KEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE-------KDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 94.3597 bits (233), Expect = 1.218e-19 Identity = 51/95 (53.68%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI AERKEAK + Q +K+
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKD 214
BLAST of SMED30015457 vs. Ensembl Mouse
Match: Smc1b (structural maintenance of chromosomes 1B [Source:MGI Symbol;Acc:MGI:2154049]) HSP 1 Score: 258.84 bits (660), Expect = 1.344e-88 Identity = 155/456 (33.99%), Postives = 267/456 (58.55%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSG-IEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFP-GVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K KIE +EA Y+ L EL +I+L L +L+YNE + N + E L + + + SH + + K ++ G + +++++ + P++IK + H + K SKK +Q ++ + L +++ +++ +E + + ++KGR++ELE +QL Y LK++V K ++ L+ L E +K+ +RR + + K+ + ++ E +KR++KL EY + + ++K+ EE ++ E+E+ R+ E+N+EL L+ L A ++ HE R K+ E++E+LKRL+P V GRLL++C P H+KYQ+A+TK+ G+YM AIV ++K AKDCI+++K +R EPETFL LD+LD++PI+E+LR+I+ +++DVI+ + +KK +QF CGN LVC+TVE AR +AF ER+K V+L
Sbjct: 197 KHAKIEKEEAEHYQNLLEELKINKIQLMLFQLYYNEEKINVLNTE--------LEQMDGNLSVVKDTLSHHENIFKAKKKDYGMLTRQLQQTAKELKSVEAILNQKRPQYIKAKENTSHHLKKLDLSKKLITDNEKQCSKQEDGIRALVAELADLDRAWKSFEKQMEEKILQKGRDIELENSQLDRYKLLKEQVRRKVGIMTQQLEKLQWEQKAEKERLAFEKRRHGDTQGNLKQIKEQIEEHKKRIEKLEEYTKTCMDCLEDKKQQEEALKKEIENTKSRMSEVNEELSLIRNELQNAGIDNHEGKRQQKRAEVLEHLKRLYPDSVFGRLLDLCHPIHKKYQLAVTKLFGRYMVAIVVASEKIAKDCIRFLKAERAEPETFLALDYLDIKPINERLREIK---GCKMMIDVIKTQFPQLKKVIQFVCGNGLVCETVEEARHIAFGGPERRKAVAL 641 HSP 2 Score: 88.5817 bits (218), Expect = 1.344e-88 Identity = 48/81 (59.26%), Postives = 59/81 (72.84%), Query Frame = -1
Query: 1353 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1595
QLE I++KA+N LVFQGTVESI+MK KER Q EEIS S EF EYE K++++K EE+A + N KKN+ AERK AK
Sbjct: 120 QLENIGIIVKAQNCLVFQGTVESISMKKPKERTQFFEEISTSGEFIGEYEAKKKKLQKAEEDAQFHFNVKKNVAAERKHAK 200
BLAST of SMED30015457 vs. Ensembl Mouse
Match: Smc4 (structural maintenance of chromosomes 4 [Source:MGI Symbol;Acc:MGI:1917349]) HSP 1 Score: 75.0998 bits (183), Expect = 1.188e-13 Identity = 109/439 (24.83%), Postives = 200/439 (45.56%), Query Frame = -2
Query: 2 VKKKEELLSHENK-RNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSRE---YNEQKDIYD----ALERRRNEIASSQKRKESEL-------NESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVV---TNLGEA------RVEKHESSRAAKKQE-------LIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1225
+ +K +LS+E K +N + ++ KVTKF IEQ +K Q E ++V +KLKH K K+ +K QLQ +++E+LKS ++ I+ RN + L+++ ++ L V+D+L +E ++K+I + + NE S + +SEL N + +L K +E + +++ + E+K A + I ++ + ++E KEL+ + NL +VE+ +SS A + + E PG++GRL ++ KY +AI+ +D IV D+ TA++C+ ++K I TF+ LD + V +K+ I+ P N + D+++ + I++A FA + LV + ++ A VA+ R + V+L
Sbjct: 349 ITEKSNVLSNEMKAKNSAVKDVEKKLNKVTKF------IEQNKEKFTQLDL-----------EDVQVREKLKHATSKAKKLEK-----------------QLQKDKEKVEELKSVPAKSKTVINETTTRN-----------NSLEKEREKEEKKLKEVMDSLKQETQGLQKEKEIQEKELMGFNKSVNEARSKMEVAQSELDIYLSRHNTAVSQLSKAKEALITASETLKERKAAIKDINTKLPQTQQELKEKEKELQKLTQEEINLKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLG-AIDEKYDIAISSCC-HALDYIVVDSIDTAQECVNFLKKHNIGIATFIGLDKMTVWA--KKMSKIQTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTL 738
BLAST of SMED30015457 vs. Ensembl Mouse
Match: Smc4 (structural maintenance of chromosomes 4 [Source:MGI Symbol;Acc:MGI:1917349]) HSP 1 Score: 75.0998 bits (183), Expect = 1.429e-13 Identity = 109/439 (24.83%), Postives = 200/439 (45.56%), Query Frame = -2
Query: 2 VKKKEELLSHENK-RNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSRE---YNEQKDIYD----ALERRRNEIASSQKRKESEL-------NESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVV---TNLGEA------RVEKHESSRAAKKQE-------LIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1225
+ +K +LS+E K +N + ++ KVTKF IEQ +K Q E ++V +KLKH K K+ +K QLQ +++E+LKS ++ I+ RN + L+++ ++ L V+D+L +E ++K+I + + NE S + +SEL N + +L K +E + +++ + E+K A + I ++ + ++E KEL+ + NL +VE+ +SS A + + E PG++GRL ++ KY +AI+ +D IV D+ TA++C+ ++K I TF+ LD + V +K+ I+ P N + D+++ + I++A FA + LV + ++ A VA+ R + V+L
Sbjct: 324 ITEKSNVLSNEMKAKNSAVKDVEKKLNKVTKF------IEQNKEKFTQLDL-----------EDVQVREKLKHATSKAKKLEK-----------------QLQKDKEKVEELKSVPAKSKTVINETTTRN-----------NSLEKEREKEEKKLKEVMDSLKQETQGLQKEKEIQEKELMGFNKSVNEARSKMEVAQSELDIYLSRHNTAVSQLSKAKEALITASETLKERKAAIKDINTKLPQTQQELKEKEKELQKLTQEEINLKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRLGDLG-AIDEKYDIAISSCC-HALDYIVVDSIDTAQECVNFLKKHNIGIATFIGLDKMTVWA--KKMSKIQTPENTPRLFDLVKVKNEEIRQAFYFALRDTLVANNLDQATRVAYQRDRRWRVVTL 713
BLAST of SMED30015457 vs. Ensembl Mouse
Match: Smc2 (structural maintenance of chromosomes 2 [Source:MGI Symbol;Acc:MGI:106067]) HSP 1 Score: 60.8474 bits (146), Expect = 3.806e-9 Identity = 38/134 (28.36%), Postives = 70/134 (52.24%), Query Frame = -2
Query: 2 VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPI-DEKLR---DIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 391
V G + + A+ V G+ + +V DT+ TAK ++ K + T +PL+ + R I E LR ++ P NVH+ L ++ ++P + +K ++F G VC+ +++A+ VAF+ +TV+L
Sbjct: 522 VKGLVASLINVKDNSTATALEVVAGERLYNVVVDTEVTAKKLLE--KGELKRRYTIIPLNKISARCIAPETLRVAQNLVGPDNVHVALSLVDYKPEL-QKGMEFVFGTTFVCNNMDNAKKVAFDKRIMTRTVTL 652
BLAST of SMED30015457 vs. UniProt/SwissProt
Match: sp|O93308|SMC1A_XENLA (Structural maintenance of chromosomes protein 1A OS=Xenopus laevis OX=8355 GN=smc1a PE=1 SV=1) HSP 1 Score: 331.257 bits (848), Expect = 4.810e-108 Identity = 195/455 (42.86%), Postives = 303/455 (66.59%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKV-----------TKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ +I+L L KL++NE E ++ KE LS +NK E D K H KV K REQ IE+EIK+ + P++IK + H + K + +KK+ ++A++Q+ + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K EL E++KR++KL EYI +S +++ EQK EET+ EVE A +RI+EIN EL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DE+LR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 208 RYQRLKDEVARAQIQLQLFKLYHNESEIEKLNKE--------LSVKNKGIEKD---KKHMDKVEEELKDKKKELGKMMREQQAIEKEIKEKD-------AELNQKLPQYIKAKENPSHKIKKFRAAKKSLQNAQKQYKKRKADMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRELEENQKRIEKLEEYIATSKQSLEEQKNLEETLTEEVEMAKRRIDEINSELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDERLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 83.9593 bits (206), Expect = 4.810e-108 Identity = 43/74 (58.11%), Postives = 54/74 (72.97%), Query Frame = -1
Query: 1371 LEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1592
LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI A
Sbjct: 121 LEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAA 194
BLAST of SMED30015457 vs. UniProt/SwissProt
Match: sp|O97593|SMC1A_BOVIN (Structural maintenance of chromosomes protein 1A OS=Bos taurus OX=9913 GN=SMC1A PE=1 SV=1) HSP 1 Score: 342.813 bits (878), Expect = 2.743e-104 Identity = 192/455 (42.20%), Postives = 315/455 (69.23%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K E +EA +Y++LK E+ +++L L KL++NEVE ++ KE K +E+ + + +++++++K +K++ K REQ IE+EIK+ P++IK + H + K + +KK+ ++A++ + + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK+ E + EVE A +RI+EINKEL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 197 KEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE-------KDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 94.3597 bits (233), Expect = 8.827e-19 Identity = 51/95 (53.68%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI AERKEAK + Q +K+
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKD 214
BLAST of SMED30015457 vs. UniProt/SwissProt
Match: sp|Q9CU62|SMC1A_MOUSE (Structural maintenance of chromosomes protein 1A OS=Mus musculus OX=10090 GN=Smc1a PE=1 SV=4) HSP 1 Score: 342.813 bits (878), Expect = 2.828e-104 Identity = 192/455 (42.20%), Postives = 315/455 (69.23%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K E +EA +Y++LK E+ +++L L KL++NEVE ++ KE K +E+ + + +++++++K +K++ K REQ IE+EIK+ P++IK + H + K + +KK+ ++A++ + + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK+ E + EVE A +RI+EINKEL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 197 KEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE-------KDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 94.3597 bits (233), Expect = 8.521e-19 Identity = 51/95 (53.68%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI AERKEAK + Q +K+
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKD 214
BLAST of SMED30015457 vs. UniProt/SwissProt
Match: sp|Q14683|SMC1A_HUMAN (Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2) HSP 1 Score: 342.428 bits (877), Expect = 3.365e-104 Identity = 192/455 (42.20%), Postives = 315/455 (69.23%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K E +EA +Y++LK E+ +++L L KL++NEVE ++ KE K +E+ + + +++++++K +K++ K REQ IE+EIK+ P++IK + H + K + +KK+ ++A++ + + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK+ E + EVE A +RI+EINKEL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 197 KEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE-------KDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 94.3597 bits (233), Expect = 8.597e-19 Identity = 51/95 (53.68%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI AERKEAK + Q +K+
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKD 214
BLAST of SMED30015457 vs. UniProt/SwissProt
Match: sp|Q9Z1M9|SMC1A_RAT (Structural maintenance of chromosomes protein 1A OS=Rattus norvegicus OX=10116 GN=Smc1a PE=1 SV=1) HSP 1 Score: 339.347 bits (869), Expect = 5.134e-103 Identity = 191/455 (41.98%), Postives = 313/455 (68.79%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K E +EA +Y+ LK E+ +++L L KL++NEVE ++ KE K +E+ + + +++++++K +K++ K REQ IE+EIK+ P++IK + H + K + +KK+ ++ ++ + + ++ +L+ +M +E+ + E+E + + S +GR+L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL EYI +S +++ EQK+ E + EVE A +RI+EINKEL V+ LG+AR+++ ESSR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR+++ LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF +R KTV+L
Sbjct: 197 KEAKQEKEEADRYQALKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE-------KDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNRQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGHQRHKTVAL 641 HSP 2 Score: 93.9745 bits (232), Expect = 9.063e-19 Identity = 51/95 (53.68%), Postives = 66/95 (69.47%), Query Frame = -1
Query: 1311 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAKNRNRRSS*IQEIKN 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY++ K+E+ K EE+ N ++KKNI AERKEAK + Q +K+
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQALKD 214
BLAST of SMED30015457 vs. TrEMBL
Match: H2KS10 (Structural maintenance of chromosome 1 (Fragment) OS=Clonorchis sinensis OX=79923 GN=CLF_107785 PE=4 SV=1) HSP 1 Score: 614.764 bits (1584), Expect = 0.000e+0 Identity = 307/455 (67.47%), Postives = 380/455 (83.52%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHEN-KRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K EIDEA +Y+KL+ +L KR ELHL KL+YN++E + +E +K++EELL+ E+ +R I+E++K R+++ K NR+QS +EQEIKKCEQ PE IKV Q L+H+ +K KESKK+ E+A+Q H ++ +E+ QL+++ ++I LK EYE +Q++ S+E+G NLELE QL EYH+LKQKVAE+TSHLSAVLD L+REYNEQKD+YDAL+RR+NEI SS KRKE+ELNE++KRLQKL EYI+SSNRAI EQ+E E+ IR EVE AT+RI+EIN ELE VV LGEA+VE+HESSRAAKKQELIENLKRLFPGVHGRLLEMCQP+HR+YQVAITKVLGKYMDAIVCD++KTAK+CIQYMKDQRIEPETFLPLDFLDV+PIDE+LR+I +PPNVHLV+DVIQ +P I+KKAL FACGNALVC+TVEHAR VA+ TGERKKTVSL
Sbjct: 160 KEAKFEIDEAERYRKLQQDLALKRTELHLFKLYYNDLEIRRV-REELKQREELLASEHEQRQSIEEEMKDKRRELGKVNRDQSSVEQEIKKCEQKIGKRR-------PEFIKVSQLLRHVTEKHKESKKSLENAKQLHSSHLQEIDQLEAESEKISSLKREYEQQQTKKSLEQGINLELEETQLNEYHRLKQKVAERTSHLSAVLDGLNREYNEQKDLYDALDRRKNEIESSLKRKETELNENKKRLQKLMEYIESSNRAITEQRETEKAIREEVEQATRRIDEINTELEAVVCQLGEAKVERHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPSHRRYQVAITKVLGKYMDAIVCDSEKTAKECIQYMKDQRIEPETFLPLDFLDVKPIDERLREISDPPNVHLVIDVIQCDPIIVKKALTFACGNALVCETVEHARYVAYQTGERKKTVSL 606 HSP 2 Score: 111.694 bits (278), Expect = 6.377e-22 Identity = 59/83 (71.08%), Postives = 65/83 (78.31%), Query Frame = -1
Query: 1353 AYQLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1601
A LE+ +I MK KNFLVFQG VESIAMKNA+ERCQ EEISKS E K EY+ +K E+ LEE TLNLNKKK IVAERKEAK
Sbjct: 81 AAALEKIHIFMKVKNFLVFQGAVESIAMKNARERCQMFEEISKSAELKEEYDNAKLEMHMLEENTTLNLNKKKGIVAERKEAK 163
BLAST of SMED30015457 vs. TrEMBL
Match: A0A419PXH1 (Structural maintenance of chromosomes protein OS=Clonorchis sinensis OX=79923 GN=Smc1a PE=3 SV=1) HSP 1 Score: 613.994 bits (1582), Expect = 0.000e+0 Identity = 307/455 (67.47%), Postives = 380/455 (83.52%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHEN-KRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K EIDEA +Y+KL+ +L KR ELHL KL+YN++E + +E +K++EELL+ E+ +R I+E++K R+++ K NR+QS +EQEIKKCEQ PE IKV Q L+H+ +K KESKK+ E+A+Q H ++ +E+ QL+++ ++I LK EYE +Q++ S+E+G NLELE QL EYH+LKQKVAE+TSHLSAVLD L+REYNEQKD+YDAL+RR+NEI SS KRKE+ELNE++KRLQKL EYI+SSNRAI EQ+E E+ IR EVE AT+RI+EIN ELE VV LGEA+VE+HESSRAAKKQELIENLKRLFPGVHGRLLEMCQP+HR+YQVAITKVLGKYMDAIVCD++KTAK+CIQYMKDQRIEPETFLPLDFLDV+PIDE+LR+I +PPNVHLV+DVIQ +P I+KKAL FACGNALVC+TVEHAR VA+ TGERKKTVSL
Sbjct: 201 KEAKFEIDEAERYRKLQQDLALKRTELHLFKLYYNDLEIRRV-REELKQREELLASEHEQRQSIEEEMKDKRRELGKVNRDQSSVEQEIKKCEQKIGKRR-------PEFIKVSQLLRHVTEKHKESKKSLENAKQLHSSHLQEIDQLEAESEKISSLKREYEQQQTKKSLEQGINLELEETQLNEYHRLKQKVAERTSHLSAVLDGLNREYNEQKDLYDALDRRKNEIESSLKRKETELNENKKRLQKLMEYIESSNRAITEQRETEKAIREEVEQATRRIDEINTELEAVVCQLGEAKVERHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPSHRRYQVAITKVLGKYMDAIVCDSEKTAKECIQYMKDQRIEPETFLPLDFLDVKPIDERLREISDPPNVHLVIDVIQCDPIIVKKALTFACGNALVCETVEHARYVAYQTGERKKTVSL 647 HSP 2 Score: 111.694 bits (278), Expect = 6.654e-22 Identity = 59/83 (71.08%), Postives = 65/83 (78.31%), Query Frame = -1
Query: 1353 AYQLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1601
A LE+ +I MK KNFLVFQG VESIAMKNA+ERCQ EEISKS E K EY+ +K E+ LEE TLNLNKKK IVAERKEAK
Sbjct: 122 AAALEKIHIFMKVKNFLVFQGAVESIAMKNARERCQMFEEISKSAELKEEYDNAKLEMHMLEENTTLNLNKKKGIVAERKEAK 204
BLAST of SMED30015457 vs. TrEMBL
Match: A0A4S2M8U9 (Structural maintenance of chromosomes protein OS=Opisthorchis felineus OX=147828 GN=CRM22_001815 PE=3 SV=1) HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0 Identity = 307/455 (67.47%), Postives = 379/455 (83.30%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHEN-KRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K K EIDEA +Y+KL+ +L KR ELHL KL+YN++E + +E +K++EELL+ E+ +R I+E++K R+++ K NR+QS +EQEIKKCEQ PE IKV Q L+H+ +K KESKK+ E+A+Q H ++ +E+ QL+++ ++I LK EYE +Q++ S+E+G NLELE QL EYH+LKQKVAE+TSHLSAVLD L+REYNEQKD+YDAL+RR+NEI SS KRKE+ELNE++KRLQKL EYI+SSNRAI EQ+E E+ IR EVE AT RI+EIN ELE VV LGEA+VE+HESSRAAKKQELIENLKRLFPGVHGRLLEMCQP+HR+YQVAITKVLGKYMDAIVCD++KTAK+CIQYMKDQRIEPETFLPLDFLDV+PIDE+LR+I +PPNVHLV+DVIQ +P I+KKAL FACGNALVC+TVEHAR VA+ TGERKKTVSL
Sbjct: 201 KEAKFEIDEAERYRKLQQDLALKRTELHLFKLYYNDLEIRRV-REELKQREELLASEHEQRQSIEEEMKDKRRELGKVNRDQSSVEQEIKKCEQKIGKRR-------PEFIKVSQLLRHVTEKHKESKKSLENAKQLHSSHLQEIDQLEAESEKISSLKREYEQQQTKKSLEQGINLELEETQLNEYHRLKQKVAERTSHLSAVLDGLNREYNEQKDLYDALDRRKNEIESSLKRKETELNENKKRLQKLMEYIESSNRAITEQRETEKAIREEVEQATSRIDEINTELEAVVCQLGEAKVERHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPSHRRYQVAITKVLGKYMDAIVCDSEKTAKECIQYMKDQRIEPETFLPLDFLDVKPIDERLREISDPPNVHLVIDVIQCDPIIVKKALTFACGNALVCETVEHARYVAYQTGERKKTVSL 647 HSP 2 Score: 112.079 bits (279), Expect = 5.514e-22 Identity = 59/83 (71.08%), Postives = 65/83 (78.31%), Query Frame = -1
Query: 1353 AYQLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1601
A LE+ +I MK KNFLVFQG VESIAMKNA+ERCQ EEISKS E K EY+ +K E+ LEE TLNLNKKK IVAERKEAK
Sbjct: 122 ATALEKIHIFMKVKNFLVFQGAVESIAMKNARERCQMFEEISKSAELKEEYDNAKLEMHMLEENTTLNLNKKKGIVAERKEAK 204
BLAST of SMED30015457 vs. TrEMBL
Match: A0A4E0RDR3 (Putative structural maintenance OS=Fasciola hepatica OX=6192 GN=D915_004696 PE=4 SV=1) HSP 1 Score: 610.912 bits (1574), Expect = 0.000e+0 Identity = 307/455 (67.47%), Postives = 384/455 (84.40%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHEN-KRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K KIEIDEA +Y++L+ +L +KR+ELHL +L+YN++E + +E +K++EE L+ E+ +R I+E++K R+++ K NR+QS +EQ+IKKCEQ PE IKV Q L+H+ +K KESKK+ E+A+Q H ++ +E+ QL+S+ ++I LK +YE +Q++ S+E+G NLELE QL EYH+LKQKVAE+TSHLSAVLD L+REYNEQKD+YDAL+RR+NEI SS KRKE+ELNE++KRLQKL+EYI+SSNRAI EQ+E E+ IR EVE ATKRI+EIN ELE VV LGEA+VE+HESSRAAKKQELIENLKRLFPGVHGRLLEMCQP+HR+YQVAITKVLGKYMDAIVCD++KTAK+CIQYMKDQRIEPETFLPLDFLDV+PIDEKLR+I +PPNVHLVLDVIQ +PAI+KKAL FACGNALVC+TVEHAR VA+N G+RKKTVSL
Sbjct: 201 KEAKIEIDEAERYRRLQQDLTSKRVELHLFRLYYNDLEIKRV-REDLKQREEALAAEHEQRQAIEEEMKEKRRELGKINRDQSSVEQDIKKCEQKIGKRR-------PEFIKVSQLLRHITEKHKESKKSLENAKQLHSSHLQEIDQLESEYEKISSLKRDYEQQQTKKSLEQGINLELEETQLSEYHRLKQKVAERTSHLSAVLDGLNREYNEQKDLYDALDRRKNEIESSMKRKETELNENKKRLQKLQEYIESSNRAITEQRETEKAIREEVEQATKRIDEINTELEAVVCQLGEAKVERHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPSHRRYQVAITKVLGKYMDAIVCDSEKTAKECIQYMKDQRIEPETFLPLDFLDVKPIDEKLREISDPPNVHLVLDVIQCDPAIVKKALTFACGNALVCETVEHARYVAYNMGDRKKTVSL 647 HSP 2 Score: 114.39 bits (285), Expect = 6.323e-23 Identity = 60/83 (72.29%), Postives = 66/83 (79.52%), Query Frame = -1
Query: 1353 AYQLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1601
A LE+ +I MK KNFLVFQG VESIAMKNA+ERCQ EEISKS E K EY+ +K E+ KLEE AT NLNKKK IVAERKEAK
Sbjct: 122 AVALEKIHIFMKVKNFLVFQGAVESIAMKNARERCQMFEEISKSAELKEEYDMAKMEMHKLEENATFNLNKKKGIVAERKEAK 204
BLAST of SMED30015457 vs. TrEMBL
Match: A0A504Y8H3 (Structural maintenance of chromosomes protein OS=Fasciola gigantica OX=46835 GN=FGIG_02989 PE=3 SV=1) HSP 1 Score: 609.757 bits (1571), Expect = 0.000e+0 Identity = 307/455 (67.47%), Postives = 384/455 (84.40%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHEN-KRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K KIEIDEA +Y++L+ +L +KR+ELHL +L+YN++E + +E +K++EE L+ E+ +R I+E++K R+++ K NR+QS +EQ+IKKCEQ PE IKV Q L+H+ +K KESKK+ E+A+Q H ++ +E+ QL+S+ ++I LK +YE +Q++ S+E+G NLELE QL EYH+LKQKVAE+TSHLSAVLD L+REYNEQKD+YDAL+RR+NEI SS KRKE+ELNE++KRLQKL+EYI+SSNRAI EQ+E E+ IR EVE ATKRI+EIN ELE VV LGEA+VE+HESSRAAKKQELIENLKRLFPGVHGRLLEMCQP+HR+YQVAITKVLGKYMDAIVCD++KTAK+CIQYMKDQRIEPETFLPLDFLDV+PIDEKLR+I +PPNVHLVLDVIQ +PAI+KKAL FACGNALVC+TVEHAR VA+N G+RKKTVSL
Sbjct: 201 KEAKIEIDEAERYRRLQQDLTSKRVELHLFRLYYNDLEIKRV-REDLKQREEALAAEHEQRQAIEEEMKEKRRELGKINRDQSSVEQDIKKCEQKIGKRR-------PEFIKVSQLLRHITEKHKESKKSLENAKQLHSSHLQEIDQLESEYEKISSLKRDYEQQQTKKSLEQGINLELEETQLSEYHRLKQKVAERTSHLSAVLDGLNREYNEQKDLYDALDRRKNEIESSMKRKETELNENKKRLQKLQEYIESSNRAITEQRETEKAIREEVEQATKRIDEINTELEAVVCQLGEAKVERHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPSHRRYQVAITKVLGKYMDAIVCDSEKTAKECIQYMKDQRIEPETFLPLDFLDVKPIDEKLREISDPPNVHLVLDVIQCDPAIVKKALTFACGNALVCETVEHARYVAYNMGDRKKTVSL 647 HSP 2 Score: 114.775 bits (286), Expect = 7.519e-23 Identity = 60/83 (72.29%), Postives = 66/83 (79.52%), Query Frame = -1
Query: 1353 AYQLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1601
A LE+ +I MK KNFLVFQG VESIAMKNA+ERCQ EEISKS E K EY+ +K E+ KLEE AT NLNKKK IVAERKEAK
Sbjct: 122 AVALEKIHIFMKVKNFLVFQGAVESIAMKNARERCQMFEEISKSAELKEEYDMAKMEMHKLEENATFNLNKKKGIVAERKEAK 204
BLAST of SMED30015457 vs. Ensembl Cavefish
Match: smc1al (structural maintenance of chromosomes 1A, like [Source:ZFIN;Acc:ZDB-GENE-040426-57]) HSP 1 Score: 327.405 bits (838), Expect = 3.783e-108 Identity = 178/444 (40.09%), Postives = 302/444 (68.02%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ ++L L KL++NE E ++ KE ++ +E+ + + +++++K +K++ + REQ +E+EIK+ P++IK + H + K + ++K+ ++A++ + + ++ +L + +E + E+E + + + +G++L+LE NQ++ YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL +YI +S ++++EQK EE + EVE A +RI+EIN EL V+ LG+AR+++ E+SR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR++R LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF R KTV+L
Sbjct: 208 RYQRLKDEVVRANVQLQLFKLYHNECEIEKLNKELSQRNKEIDKDRKRMDRVEDELKDKKKELGRMMREQQTVEKEIKE-------KDAELNQKRPQYIKAKENTAHKIKKLEAARKSLQNAQKCYKKRKADMDELDKEQKAVEMARQEFEERMEEEAQSQGQDLQLEENQVKAYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKIREIEENQKRIEKLEDYITTSRQSLDEQKRMEEELTEEVEQAKRRIDEINMELNQVMEQLGDARIDRQENSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELR---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGPYRHKTVAL 641 HSP 2 Score: 85.1149 bits (209), Expect = 3.783e-108 Identity = 44/74 (59.46%), Postives = 54/74 (72.97%), Query Frame = -1
Query: 1371 LEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1592
LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY+R K+E+ K EE+ N ++KKNI A
Sbjct: 121 LEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDRRKKEMVKAEEDTQFNYHRKKNIAA 194
BLAST of SMED30015457 vs. Ensembl Cavefish
Match: smc1a (structural maintenance of chromosomes 1A [Source:NCBI gene;Acc:103021942]) HSP 1 Score: 315.464 bits (807), Expect = 1.095e-104 Identity = 178/444 (40.09%), Postives = 300/444 (67.57%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ ++L L KL++NE E ++ KE ++ E+ K + I+E++K +K++ + R+Q +E+EIK+ P +IK + H + K + ++K+ ++A++ + + ++ +L + +E + E+E + + + +G++L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL +YI +S ++++EQ+ EE + EVE A +RI+EIN EL V+ LG+AR+++ E+SR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR++R LV+DVI++EP IKKALQ+ACGNALVC+ VE AR +AF R KTV+L
Sbjct: 208 RYQRLKDEVVRAHVQLQLFKLYHNEAEIEKLNKELSQRNREIEKDRKKMDHIEEELKEKKKELGRMMRDQQNVEKEIKE-------KDAELNQKRPLYIKAKENTSHKIKKLEAARKSLQNAQKMYKKRKADMDELDREQGAVETARQEFEERMEEEAQSQGQDLTLEENQVKQYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKIREIEENQKRIEKLEDYIATSRQSLDEQRRMEEELTEEVELAKRRIDEINMELNQVMEQLGDARIDRQENSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELR---GAKLVIDVIRYEPPHIKKALQYACGNALVCENVEDARRIAFGGPYRHKTVAL 641 HSP 2 Score: 85.5001 bits (210), Expect = 1.095e-104 Identity = 44/75 (58.67%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY+R K+E+ K EE+ N ++KKNI A
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDRRKKEMVKAEEDTQFNYHRKKNIAA 194
BLAST of SMED30015457 vs. Ensembl Cavefish
Match: smc1b (structural maintenance of chromosomes 1B [Source:ZFIN;Acc:ZDB-GENE-091217-1]) HSP 1 Score: 224.557 bits (571), Expect = 4.679e-63 Identity = 108/235 (45.96%), Postives = 174/235 (74.04%), Query Frame = -2
Query: 2 RRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGV-HGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFE--PAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 697
RR+NE+A++ K +++L++ +R KL +Y+ +SN+A+ EQ+E EE + E+E R++E+N+EL V++ L A ++ E+ R K+ E+ ++L RL+P V +GRL+++CQP H+KYQ+A+TKV G+YM+AIV + K A+DCIQ++K++R EPETFLP+++LDV P++E+LR++R LV+DV+Q +K+ +QF CGNALVC+T++ ART+AF ER+KTV+L
Sbjct: 343 RRKNEVAANIKHSQTQLDDLTRRAGKLEDYVITSNKALAEQREQEECLAEELECGRVRMQEVNEELAGVLSELQNAGIDSQENRRQQKRNEVFDSLHRLYPDVVYGRLVDLCQPIHKKYQLAVTKVFGRYMNAIVVSSAKVARDCIQFIKEERAEPETFLPIEYLDVNPLNERLREVR---GAKLVVDVVQCSQNAPQLKRVVQFVCGNALVCETLKDARTIAFGGPERRKTVAL 574 HSP 2 Score: 66.6254 bits (161), Expect = 4.755e-11 Identity = 35/79 (44.30%), Postives = 51/79 (64.56%), Query Frame = -1
Query: 1359 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKE 1595
QLE+ I++KA+N LVFQG VES+AM NAKER + E IS S E +Y ++K +E + N+K+ +AE+K+
Sbjct: 120 QLEKIGIVVKARNCLVFQGAVESLAMMNAKERTKLFEHISNSAELAKDYNTKLTALKKAKENTQFHFNRKRAAIAEKKQ 198
BLAST of SMED30015457 vs. Ensembl Cavefish
Match: smc1b (structural maintenance of chromosomes 1B [Source:ZFIN;Acc:ZDB-GENE-091217-1]) HSP 1 Score: 224.172 bits (570), Expect = 4.713e-63 Identity = 108/235 (45.96%), Postives = 174/235 (74.04%), Query Frame = -2
Query: 2 RRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGV-HGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFE--PAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 697
RR+NE+A++ K +++L++ +R KL +Y+ +SN+A+ EQ+E EE + E+E R++E+N+EL V++ L A ++ E+ R K+ E+ ++L RL+P V +GRL+++CQP H+KYQ+A+TKV G+YM+AIV + K A+DCIQ++K++R EPETFLP+++LDV P++E+LR++R LV+DV+Q +K+ +QF CGNALVC+T++ ART+AF ER+KTV+L
Sbjct: 343 RRKNEVAANIKHSQTQLDDLTRRAGKLEDYVITSNKALAEQREQEECLAEELECGRVRMQEVNEELAGVLSELQNAGIDSQENRRQQKRNEVFDSLHRLYPDVVYGRLVDLCQPIHKKYQLAVTKVFGRYMNAIVVSSAKVARDCIQFIKEERAEPETFLPIEYLDVNPLNERLREVR---GAKLVVDVVQCSQNAPQLKRVVQFVCGNALVCETLKDARTIAFGGPERRKTVAL 574 HSP 2 Score: 66.2402 bits (160), Expect = 5.175e-11 Identity = 35/79 (44.30%), Postives = 51/79 (64.56%), Query Frame = -1
Query: 1359 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKE 1595
QLE+ I++KA+N LVFQG VES+AM NAKER + E IS S E +Y ++K +E + N+K+ +AE+K+
Sbjct: 120 QLEKIGIVVKARNCLVFQGAVESLAMMNAKERTKLFEHISNSAELAKDYNTKLTALKKAKENTQFHFNRKRAAIAEKKQ 198
BLAST of SMED30015457 vs. Ensembl Cavefish
Match: smc4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:103045898]) HSP 1 Score: 81.2629 bits (199), Expect = 1.086e-15 Identity = 85/335 (25.37%), Postives = 162/335 (48.36%), Query Frame = -2
Query: 2 QLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQ---KVAEKTSHLS-------AVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEAR---------VEKHESSRAAKKQ--ELIENLKRL-----FPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 928
QLQ +++E++++ + I+ + ELE +++E L Q + E+TS L L LS+ NE + D + + S S+LN++++ LQ + + E++ A + ++V++ + +++ +ELE + GEAR VE+ +SS ++ + ++++ L + PG+ GRL ++ R Y VAI+ G +D I+ DT TA+ C+ ++K Q I TF+ LD + V ++ + I P N+ + D+++ + ++ A FA + LV +E A VAF +R + V+L
Sbjct: 424 QLQKDKEKLEEVRNVPASSEKIITEASAQKEELEKQKVKEEESLAQVMESLKEETSGLQNEKEQKEKELLELSKAVNETRSQMDVAQSELDIYLSQHNTAVSQLNQAKETLQ-------GTADTLRERRAAIKDLQVKIPKCEQELKKDEQELEQISGQDGEARGVVSDLRQKVEEAKSSLSSNRSRGKVLDALMQQKQSGKIPGIFGRLGDLGAIDER-YDVAISSSCGS-LDNILVDTIDTAQKCVVFLKSQNIGVATFIGLDKMKV--WEKNMVAISTPENIPRLFDMVKVKDESVRPAFYFALRDTLVAKDLEQATRVAFQKDKRWRVVTL 747
BLAST of SMED30015457 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000346.1 (pep scaffold:Pmarinus_7.0:GL477118:44770:74561:-1 gene:ENSPMAG00000000296.1 transcript:ENSPMAT00000000346.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 284.648 bits (727), Expect = 4.224e-95 Identity = 156/456 (34.21%), Postives = 281/456 (61.62%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYE-LKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K ++E +EA Y+ L+ EL + +L+L L++NE + ++ E ++L + D++++ ++++ + RE +E+ IK E P++IKV + + H + + + +++ ++AR + + ++++ +L+ ++ +E+ + E+E L +Q E + E++ +Q+ EY++LK++V + ++ L+ R ++ + R+ E S K+K+ E + + R++K+++YI+ + AI E + ++ +VE A +R EIN E+ + LG+AR E+HE+ R ++ E +++L RLFPG + GRL+ +CQP HRKYQ+A+TKVLG+ M+AI+ DT TA+DCI+Y+K+QR E E FLPLD+L VRPI+E+LR++R L++DVI+F+P + +ALQFAC NALVC+T+E AR +AF + R+K VSL
Sbjct: 197 KEARLEKEEAENYRHLRDELASAHTQLNLFLLYHNEQQMKVLENELAGVGDQLDQQRALMSTTDDELRVRKQEIGRLGRELQQVEKAIKAKEMDLGQSK-------PQYIKVKENISHRLRRMESTRQLLQNARAEWIRRKKDIDELERELVAVERARQEFEQLVGTQSQSE---DFEIDESQVLEYYRLKEEVGRRAGGMTQELETFKRAQKADQEHLELETRKMKETQSKVKQKQQEYEDQQNRIEKIKQYIEKTRSAIEELDVEQVSLTEQVEGARRRALEINDEVVALTAQLGDARTEQHENKRFKRRAEALDSLLRLFPGAIFGRLVNLCQPTHRKYQLAVTKVLGRNMEAIIVDTDSTARDCIRYLKEQRCEAEMFLPLDYLQVRPINERLRELR---GAKLLMDVIKFDPPQVSRALQFACSNALVCETLEDARHIAFGSHVRQKCVSL 639 HSP 2 Score: 82.0333 bits (201), Expect = 4.224e-95 Identity = 45/81 (55.56%), Postives = 55/81 (67.90%), Query Frame = -1
Query: 1353 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1595
QL + IL KA+NFLVFQG VESIAMK KER E+IS+S E AEYE+ K + K E+ N + K+NI AERKEA+
Sbjct: 120 QLAKRGILTKARNFLVFQGAVESIAMKTPKERTWLFEQISQSGELAAEYEQCKTAMLKANEDTQFNYHCKRNITAERKEAR 200
BLAST of SMED30015457 vs. Ensembl Sea Lamprey
Match: SMC1A (structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111]) HSP 1 Score: 249.98 bits (637), Expect = 2.514e-74 Identity = 127/274 (46.35%), Postives = 193/274 (70.44%), Query Frame = -2
Query: 2 QLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLF-PGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 820
Q++ Y+ LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E+ KR++KL EYI +S ++ EQK+ E + EVE+A +RIEEIN EL V+ LG+AR+++ E+SR ++ E++E+LKRL+ V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR PE P V+P DEKLR++R LV+DVI++EP IKKALQ+ACGN+LVC+ VE AR +AF +R K V+L
Sbjct: 1 QVKVYNSLKEEASKRAAVLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENHKRVEKLEEYIVTSRSSLEEQKKLESQLTEEVETAKRRIEEINNELNQVMGQLGDARIDRQENSRQQRRVEIMESLKRLYSSSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYVKEQRDFPEPLPPFCGRQVKPTDEKLRELR---GAKLVIDVIRYEPPQIKKALQYACGNSLVCENVEDARRIAFGGPQRHKAVAL 271
BLAST of SMED30015457 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002584.1 (pep scaffold:Pmarinus_7.0:GL477247:652:6382:-1 gene:ENSPMAG00000002354.1 transcript:ENSPMAT00000002584.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 99.7525 bits (247), Expect = 2.123e-24 Identity = 52/81 (64.20%), Postives = 61/81 (75.31%), Query Frame = -1
Query: 1353 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER Q EEIS+S E EYER K E+ K EE+ N ++KKNI AERKEAK
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTQLFEEISRSGELATEYERRKREMMKAEEDTQFNYHRKKNIAAERKEAK 200
BLAST of SMED30015457 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008608.1 (pep scaffold:Pmarinus_7.0:GL477381:37203:71735:-1 gene:ENSPMAG00000007778.1 transcript:ENSPMAT00000008608.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 77.0258 bits (188), Expect = 5.645e-15 Identity = 78/296 (26.35%), Postives = 133/296 (44.93%), Query Frame = -2
Query: 2 NLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVE------KHESSRAA-----KKQELIENL-----KRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 841
N E ET LQE ++KQ+ L ALS+E NE+ + + + S + LNE+++ L S+ + ++E + + S K + + ELE + AR E K E ++++ + ++++ L K PG++GRL ++ KY VAI+ G +D IV DT TA+ C+ Y+K I TF+ LD + V K + ++ P V + D+++ ++ A F + LV + +E A VAF R + V+L
Sbjct: 474 NFEKETKGLQEEKEVKQQE----------LLALSKEVNERCSRMEVAQSELDLYMSRHTSALAALNEAKQALT-------STTEGLCGRRENIRKLETTIPSTEKELAQAQLELEKLAPLENAARAEVRALRQKTEEAKSSLCASRSRNKVLQLLMDQKNKGSLPGIYGRLGDLG-AIEEKYDVAISSCCGA-LDNIVVDTMDTAQACVTYLKKHNIGSATFIGLDKMRVWEGTMK-KSVQGPEGVLRLFDLVRVGDEAVRTAFYFTLRDTLVANNLEQASRVAFQHQRRWRVVTL 749
BLAST of SMED30015457 vs. Ensembl Yeast
Match: SMC1 (Subunit of the multiprotein cohesin complex; essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure [Source:SGD;Acc:S000001886]) HSP 1 Score: 120.553 bits (301), Expect = 4.074e-29 Identity = 85/302 (28.15%), Postives = 163/302 (53.97%), Query Frame = -2
Query: 2 EYELKQSQISVEKGRNLELETNQLQEYHKLKQK-VAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRL----QKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDV--IQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 886
E E+KQS + +K +L N L+ Y+ L +K + E S L + L+ N++++I + LER S++R EL+ + ++L LR ++ N E+ + ++ ++ESA + ++N +L + + + + E+ + K +E I LKR FPGV G + ++C P KY +A++ +LGK D+++ + A++CI ++K QR +F+PLD I+ +L + P + +L + I +EP +KA+Q+ CG++++C+T+ A+ + + G R K V++
Sbjct: 365 EEEIKQSARNYDK---FKLNENDLKTYNCLHEKYLTEGGSILEEKIAVLN---NDKREIQEELERFNKRADISKRRITEELSITGEKLDTQLNDLRVSLNEKNALHTERLHELKKLQSDIESANNQEYDLNFKLRETLVKIDDLSANQRETMKERKLRENIAMLKRFFPGVKGLVHDLCHPKKEKYGLAVSTILGKNFDSVIVENLTVAQECIAFLKKQRAGTASFIPLD-----TIETELPTLSLPDSQDYILSINAIDYEPE-YEKAMQYVCGDSIICNTLNIAKDLKWKKGIRGKLVTI 654 HSP 2 Score: 47.7506 bits (112), Expect = 3.796e-6 Identity = 25/43 (58.14%), Postives = 31/43 (72.09%), Query Frame = -1
Query: 1464 LEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIE 1592
LE NIL+KAKNFLVFQG VE IA ++ E + EE+S SI+
Sbjct: 135 LENENILIKAKNFLVFQGDVEQIAAQSPVELSRMFEEVSGSIQ 177
BLAST of SMED30015457 vs. Ensembl Yeast
Match: SMC2 (Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; essential SMC chromosomal ATPase family member that forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for clustering of tRNA genes at the nucleolus [Source:SGD;Acc:S000001927]) HSP 1 Score: 63.1586 bits (152), Expect = 6.762e-11 Identity = 40/136 (29.41%), Postives = 75/136 (55.15%), Query Frame = -2
Query: 2 GVHGRLLEMCQPAHRKYQVAI-TKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPE-TFLPLDFLDVRPIDEKLRDIRE---PPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 394
GV G+L ++ R Y A+ T G+ + +V D+Q Q ++ R+ T +PLD + RPI ++ D+ + P V L +++I+F+ +I K A++F GN+L+C+ E A+ + F+ R ++++L
Sbjct: 525 GVVGQLFQIDNDNIR-YATALQTCAGGRLFNVVVQDSQTAT----QLLERGRLRKRVTIIPLDKIYTRPISSQVLDLAKKIAPGKVELAINLIRFDESITK-AMEFIFGNSLICEDPETAKKITFHPKIRARSITL 654
BLAST of SMED30015457 vs. Ensembl Nematostella
Match: EDO49596 (Structural maintenance of chromosomes protein [Source:UniProtKB/TrEMBL;Acc:A7RFF3]) HSP 1 Score: 309.301 bits (791), Expect = 2.906e-98 Identity = 180/451 (39.91%), Postives = 291/451 (64.52%), Query Frame = -2
Query: 2 KIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1354
K E +EA KY K +L EL L KL++NE + + + E K E ++K+ +++Q+K +++ K RE IE+ I++ E P IK +K H+M + + SKKA E A+ +Q E+ +L++ ++ ++QL ++YE Q + +G +LEL +QL+EY++LK++ +T+ + LD ++RE +++ D +++ + ++ + QK+ + + + R+R+ KL EY+ ++ + + K E++ EV A R +I+ +LE V L EA+ KHES+R KK+E+++++KRLFPGVHGRL+E+C+P H+KY +A+TKVLG MDA++ D++KTAKDCIQY+K+QR + ETFLPLD + V+P++E+LR I N L++DVI++ PA++KKALQ+ACGNALVCDT+E AR +AF ERKKTVSL
Sbjct: 185 KQEKEEADKYNKWNQDLVDSLQELQLFKLYHNEQDISHMTSEMKTKSRETEKLDSKKQAVEKQLKGKKQENAKLTREMGIIEKTIREKEDELNKKR-------PAFIKAKEKTSHVMKRHETSKKALEKAKAARKRHQAEIEELKNSLEEVKQLAAQYE--QEVAAESQGEDLELMDSQLEEYNRLKEEARRETAAVRQQLDRINREQQSDQELLDGVKQTKTDLKTRQKQLQEQSVQLRERIDKLEEYLTTNVEHVEKLKAESESLSSEVSDANTRHHDISGKLESVQLELNEAKSNKHESARHQKKKEVLDSMKRLFPGVHGRLIELCEPTHKKYNLAVTKVLGMNMDAVIVDSEKTAKDCIQYLKEQRADRETFLPLDAIKVKPVNEQLRQI--GGNTKLLIDVIRYSPAVVKKALQYACGNALVCDTMEEARKIAFGGSERKKTVSL 624 HSP 2 Score: 68.5514 bits (166), Expect = 2.906e-98 Identity = 37/65 (56.92%), Postives = 45/65 (69.23%), Query Frame = -1
Query: 1353 FQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1547
F GTVESIAMK KER E+IS+S E YE+ K E++K EEE + N +KKK I AER+EAK
Sbjct: 121 FGGTVESIAMKTPKERTAMFEKISRSGELADSYEKKKAEMQKAEEETSFNYHKKKGIAAERREAK 185
BLAST of SMED30015457 vs. Ensembl Nematostella
Match: EDO40646 (Structural maintenance of chromosomes protein [Source:UniProtKB/TrEMBL;Acc:A7S6N1]) HSP 1 Score: 94.7449 bits (234), Expect = 2.144e-20 Identity = 49/133 (36.84%), Postives = 76/133 (57.14%), Query Frame = -2
Query: 2 FPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 400
PG++GRL ++ KY +AI+ G +D IVCDT +TA+ C+QY+K I TF+ LD ++V D + I+ P NV + D+++ + A + A FA N LV D +E A +AF +R + V+L
Sbjct: 544 IPGLYGRLGDLG-AIDDKYDIAISTACGA-LDHIVCDTMETAQTCVQYLKKNNIGAATFIGLDKVEVWRKDASSK-IQTPSNVPRLYDLVRVKDAKVSTAFYFALRNTLVADELEQATRIAFQGNKRWRVVTL 673
BLAST of SMED30015457 vs. Ensembl Nematostella
Match: EDO27517 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T917]) HSP 1 Score: 60.8474 bits (146), Expect = 9.130e-11 Identity = 27/63 (42.86%), Postives = 39/63 (61.90%), Query Frame = -2
Query: 212 FPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLD 400
PG++GRL ++ KY +AI+ G +D IVCDT +TA+ C+QY+K I TF+ LD
Sbjct: 139 IPGLYGRLGDL-GAIDDKYDIAISTACGA-LDHIVCDTMETAQTCVQYLKKNNIGAATFIGLD 199
BLAST of SMED30015457 vs. Ensembl Medaka
Match: smc1al (structural maintenance of chromosomes 1A [Source:NCBI gene;Acc:100049244]) HSP 1 Score: 328.176 bits (840), Expect = 1.496e-108 Identity = 182/444 (40.99%), Postives = 304/444 (68.47%), Query Frame = -2
Query: 2 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPG-VHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1330
+Y++LK E+ ++L L KL++NE E ++ KE ++ +E+ K + ++E++K +K++ + REQ IE+EIK+ + P++IK + H + K + ++K+ ++A++ + + ++ +L +M +E K ++E + + + +G++L LE NQ+++YH+LK++ +++ + L+ L+ +R+ +D D ER++ E + K+K E+ E++KR++KL +YI +S ++++EQK EE + EVE A +RI+EIN EL V+ LG+AR+++ E+SR +K E++E++KRL+PG V+GRL+++CQP +KYQ+A+TKVLGK MDAI+ D++KT +DCIQY+K+QR EPETFLPLD+L+V+P DEKLR++R LV+DVI++EP IKKALQ+ACGNALVCD VE AR +AF R KTV+L
Sbjct: 208 RYQRLKDEVARASVQLQLFKLYHNETEIEKLNKELGQRNKEIDKDRKKMDHVEEELKDKKKELGRMMREQQTIEKEIKEKD-------SELNQKRPQYIKAKENTAHKIKKLEAARKSLQNAQKMYKKRKADMDELDKEMRAVEIAKQDFEERMEEEAQSQGQDLTLEENQVKQYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKIREIEENQKRIEKLEDYIATSRQSLDEQKRMEEELTEEVEMAKRRIDEINMELNQVMEQLGDARIDRQENSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELR---GAKLVIDVIRYEPPHIKKALQYACGNALVCDNVEDARRIAFGGPYRHKTVAL 641 HSP 2 Score: 85.5001 bits (210), Expect = 1.496e-108 Identity = 44/75 (58.67%), Postives = 55/75 (73.33%), Query Frame = -1
Query: 1371 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVA 1595
+LE+ IL+KA+NFLVFQG VESIAMKN KER EEIS+S E EY+R K+E+ K EE+ N ++KKNI A
Sbjct: 120 ELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDRRKKEMVKAEEDTQFNYHRKKNIAA 194
BLAST of SMED30015457 vs. Ensembl Medaka
Match: smc1b (meiosis-specific cohesin subunit SMC1 beta [Source:NCBI gene;Acc:100049500]) HSP 1 Score: 264.618 bits (675), Expect = 3.649e-83 Identity = 162/453 (35.76%), Postives = 269/453 (59.38%), Query Frame = -2
Query: 2 EAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREY--NEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFP-GVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQF----EPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1339
EA KY++L EL+ R++L L +L+YNE N I +++ + +++ +++ +K H+K+ REQ E+EI+ E +++K H M K +E + A + R+ Q++L + Q ++ +E+ YE + Q K R++EL +Q++ Y +LK+ V ++ + S + L E N +K +D +RR+ E+ + + + L + R +KL+EYI S ++ + + EE + E++ A +R E+N EL V+ LG AR++ HES R +++EL+E L RLFP V+GRL ++C P H+KYQ+A+TKV G M+AIV ++KTA+DCI +MK +R EPETFLP+D+L V P++E+LR+I P +V+DV+QF A +KK +Q+ CGNALVC++++ AR++AF+ +R KTVSL
Sbjct: 205 EAQKYQELLDELHENRLQLSLAELYYNEKAINTISDTLSERQNAVAVKKSELANLEQMVKLHKKEHGHLTREQQHTEKEIRDQEHALSQSR-------SQYVKAKVNTSHHMKKIEEGRCAVKKKRKCLTHKQQQLKEDQLEITELEKAWKSYEKQVQQEGASKRRDIELNEDQVERYDELKKLVRKQGAVFSQQAEKLQWELKANSEKIAFD--QRRKKEMEIAIRNSLTHLEDMTSRSEKLKEYIKSCTSSLEDCCQKEEKLSAELQWAAQRSVEVNHELTQVMEELGNARLDSHESRRQLQRRELLEKLCRLFPENVYGRLSDLCSPIHKKYQLAVTKVFGSNMNAIVVSSEKTARDCISFMKAERAEPETFLPIDYLVVSPLNERLREI---PGAKMVVDVVQFNMSTNAAQLKKVVQYVCGNALVCESIKDARSLAFDQEQRVKTVSL 645 HSP 2 Score: 64.3142 bits (155), Expect = 3.649e-83 Identity = 35/79 (44.30%), Postives = 54/79 (68.35%), Query Frame = -1
Query: 1359 QLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKE 1595
+LE+ +I+ K +N +VFQGTVE IA+K+ KER + +E IS+S E+ AEY K + K +E+ + NKKK+ E+K+
Sbjct: 120 ELEKLSIMTKVQNCMVFQGTVELIALKDPKERTKMLESISQSREYAAEYNAKKAALLKAKEDTQFHFNKKKSATVEKKQ 198
BLAST of SMED30015457 vs. Ensembl Medaka
Match: smc1b (meiosis-specific cohesin subunit SMC1 beta [Source:NCBI gene;Acc:100049500]) HSP 1 Score: 264.233 bits (674), Expect = 1.627e-77 Identity = 162/453 (35.76%), Postives = 269/453 (59.38%), Query Frame = -2
Query: 2 EAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREY--NEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFP-GVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQF----EPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1339
EA KY++L EL+ R++L L +L+YNE N I +++ + +++ +++ +K H+K+ REQ E+EI+ E +++K H M K +E + A + R+ Q++L + Q ++ +E+ YE + Q K R++EL +Q++ Y +LK+ V ++ + S + L E N +K +D +RR+ E+ + + + L + R +KL+EYI S ++ + + EE + E++ A +R E+N EL V+ LG AR++ HES R +++EL+E L RLFP V+GRL ++C P H+KYQ+A+TKV G M+AIV ++KTA+DCI +MK +R EPETFLP+D+L V P++E+LR+I P +V+DV+QF A +KK +Q+ CGNALVC++++ AR++AF+ +R KTVSL
Sbjct: 192 EAQKYQELLDELHENRLQLSLAELYYNEKAINTISDTLSERQNAVAVKKSELANLEQMVKLHKKEHGHLTREQQHTEKEIRDQEHALSQSR-------SQYVKAKVNTSHHMKKIEEGRCAVKKKRKCLTHKQQQLKEDQLEITELEKAWKSYEKQVQQEGASKRRDIELNEDQVERYDELKKLVRKQGAVFSQQAEKLQWELKANSEKIAFD--QRRKKEMEIAIRNSLTHLEDMTSRSEKLKEYIKSCTSSLEDCCQKEEKLSAELQWAAQRSVEVNHELTQVMEELGNARLDSHESRRQLQRRELLEKLCRLFPENVYGRLSDLCSPIHKKYQLAVTKVFGSNMNAIVVSSEKTARDCISFMKAERAEPETFLPIDYLVVSPLNERLREI---PGAKMVVDVVQFNMSTNAAQLKKVVQYVCGNALVCESIKDARSLAFDQEQRVKTVSL 632
BLAST of SMED30015457 vs. Ensembl Medaka
Match: smc4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:101157474]) HSP 1 Score: 80.8777 bits (198), Expect = 1.634e-15 Identity = 89/332 (26.81%), Postives = 164/332 (49.40%), Query Frame = -2
Query: 2 QLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQ---KVAEKTSHL-------SAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELEL------VVTNLGEARVEKHESSRAAKKQ--ELIENLKRL-----FPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 928
QL+ + ++E+++S + IS R +LE +++E KLK+ + E+TS L L LS+ NE + D + + S K ++LN +++ LQ + + AI K+ E I +V+ K EE+ K ++ VV L E +V++ ++S ++ + ++++ L +L PG++GRL ++ KY VAI+ G +D IV DT TA+ C+ ++K+Q I TF+ LD ++ ++ + IR P + + D+++ ++ A FA + LV +E A +AF +R + V+L
Sbjct: 400 QLEKEQKKLEEVQSIPSSSEKAISEATARKEDLEKQKVKEEDKLKEVMESLKEETSGLQQDKEKKEKELMELSKAVNETRSRMDLAQSELDIYLSRHKTALAQLNTAKQTLQTTSDTLKERRAAI---KDLEVQIPEKVQELKKDQEELEKLTKMDNETREVVKELRE-KVDEAKTSLSSNRSRGKVLDALMQLKKTGRIPGIYGRLGDLG-AIDEKYDVAISSCCGA-LDNIVVDTIDTAQKCVTFLKEQNIGVATFIGLD--KMKTWEKNMAPIRTPEDSPRLFDMVRVNDDSVRPAFYFALRDTLVAQDMEQATRMAFQKEKRWRVVTL 723
BLAST of SMED30015457 vs. Ensembl Medaka
Match: smc4 (structural maintenance of chromosomes 4 [Source:NCBI gene;Acc:101157474]) HSP 1 Score: 80.8777 bits (198), Expect = 1.697e-15 Identity = 89/332 (26.81%), Postives = 164/332 (49.40%), Query Frame = -2
Query: 2 QLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQ---KVAEKTSHL-------SAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELEL------VVTNLGEARVEKHESSRAAKKQ--ELIENLKRL-----FPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 928
QL+ + ++E+++S + IS R +LE +++E KLK+ + E+TS L L LS+ NE + D + + S K ++LN +++ LQ + + AI K+ E I +V+ K EE+ K ++ VV L E +V++ ++S ++ + ++++ L +L PG++GRL ++ KY VAI+ G +D IV DT TA+ C+ ++K+Q I TF+ LD ++ ++ + IR P + + D+++ ++ A FA + LV +E A +AF +R + V+L
Sbjct: 422 QLEKEQKKLEEVQSIPSSSEKAISEATARKEDLEKQKVKEEDKLKEVMESLKEETSGLQQDKEKKEKELMELSKAVNETRSRMDLAQSELDIYLSRHKTALAQLNTAKQTLQTTSDTLKERRAAI---KDLEVQIPEKVQELKKDQEELEKLTKMDNETREVVKELRE-KVDEAKTSLSSNRSRGKVLDALMQLKKTGRIPGIYGRLGDLG-AIDEKYDVAISSCCGA-LDNIVVDTIDTAQKCVTFLKEQNIGVATFIGLD--KMKTWEKNMAPIRTPEDSPRLFDMVRVNDDSVRPAFYFALRDTLVAQDMEQATRMAFQKEKRWRVVTL 745
BLAST of SMED30015457 vs. Planmine SMEST
Match: SMESG000022017.1 (SMESG000022017.1) HSP 1 Score: 875.159 bits (2260), Expect = 0.000e+0 Identity = 438/454 (96.48%), Postives = 439/454 (96.70%), Query Frame = -2
Query: 2 KRQKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 1363
K KIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQ PEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVV+NLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL
Sbjct: 203 KEAKIEIDEAAKYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQDISKKR-------PEHIKVHQKLKHLMDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAVLDALSREYNEQKDIYDALERRRNEIASSQKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVSNLGEARVEKHESSRAAKKQELIENLKRLFPGVHGRLLEMCQPAHRKYQVAITKVLGKYMDAIVCDTQKTAKDCIQYMKDQRIEPETFLPLDFLDVRPIDEKLRDIREPPNVHLVLDVIQFEPAIIKKALQFACGNALVCDTVEHARTVAFNTGERKKTVSL 649 HSP 2 Score: 158.688 bits (400), Expect = 7.302e-41 Identity = 81/83 (97.59%), Postives = 81/83 (97.59%), Query Frame = -1
Query: 1353 AYQLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQNVEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 1601
AYQLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQ EEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK
Sbjct: 124 AYQLEQFNILMKAKNFLVFQGTVESIAMKNAKERCQMFEEISKSIEFKAEYERSKEEVRKLEEEATLNLNKKKNIVAERKEAK 206
BLAST of SMED30015457 vs. Planmine SMEST
Match: SMESG000056013.1 (SMESG000056013.1) HSP 1 Score: 50.447 bits (119), Expect = 4.174e-6 Identity = 73/334 (21.86%), Postives = 137/334 (41.02%), Query Frame = -2
Query: 401 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLM---DKQKESKKAYESARQQHLANQEELAQLQSQM-DRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAV---LDALSREYNEQKDIYDALERR---------RNEIASS--------QKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRL 1330
K+ KLK E+ I+ +K E + EI+K + + L + +I+E I H EQ GI E+ K P LK ++ D+ + K +S Q N ++ + ++ M D I EY S E + L ++++ K+ +K+ ++ +L LDA+S+ + ++KD+ R N + S +K E +LN+S ++KL + + + A + KEA I ++ + I + KEL+ +N+ ++K + + K E++EN+K +
Sbjct: 1367 KFYKLKNEIKNFSIQFQKMKDDAKE-KYGEIEKLKTRYNKILEDLRSTFTDINETISGH---------EQLGISNELIKNATAYLETIKNIYKEMPNITLAASVLKDVLKYVDELNQIIKYTQSHIQSDQINNLKILKNKTIMADEINTNNKEYLNTMSTKKKEHELYIILINERMKDLQKIFRKMTKQRDNLRKKIQKLDAISKSFQDEKDLISINVREIEDLMKNLSSNHLVSKSLIIPDTLKKHVEQQLNKSSNLIKKLTKDFNFLHNA-EQAKEAYSNITRDILAVDYAINQTKKELDFNRSNMNIDSLKKLLAEFNSNKSEIVENIKNI 1689
BLAST of SMED30015457 vs. Planmine SMEST
Match: SMESG000056013.1 (SMESG000056013.1) HSP 1 Score: 50.0618 bits (118), Expect = 4.863e-6 Identity = 71/334 (21.26%), Postives = 137/334 (41.02%), Query Frame = -2
Query: 401 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLM---DKQKESKKAYESARQQHLANQEELAQLQSQM-DRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAV---LDALSREYNEQKDIYDALERRRNEIASS-----------------QKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRL 1330
K+ KLK E+ I+ +K E + EI+K + + L + +I+E I H EQ GI E+ K P LK ++ D+ + K +S Q N ++ + ++ M D I EY S E + L ++++ K+ +K+ ++ +L LDA+S+ + ++KD+ R ++ + +K E +LN+S ++KL + + + A + KEA I ++ + I + KEL+ +N+ ++K + + K E++EN+K +
Sbjct: 1334 KFYKLKNEIKNFSIQFQKMKDDAKE-KYGEIEKLKTRYNKILEDLRSTFTDINETISGH---------EQLGISNELIKNATAYLETIKNIYKEMPNITLAASVLKDVLKYVDELNQIIKYTQSHIQSDQINNLKILKNKTIMADEINTNNKEYLNTMSTKKKEHELYIILINERMKDLQKIFRKMTKQRDNLRKKIQKLDAISKSFQDEKDLISINVREIEDLMKNLSSNHLVSKSLIIPDTLKKHVEQQLNKSSNLIKKLTKDFNFLHNA-EQAKEAYSNITRDILAVDYAINQTKKELDFNRSNMNIDSLKKLLAEFNSNKSEIVENIKNI 1656
BLAST of SMED30015457 vs. Planmine SMEST
Match: SMESG000056013.1 (SMESG000056013.1) HSP 1 Score: 50.0618 bits (118), Expect = 4.904e-6 Identity = 71/334 (21.26%), Postives = 137/334 (41.02%), Query Frame = -2
Query: 401 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLM---DKQKESKKAYESARQQHLANQEELAQLQSQM-DRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAV---LDALSREYNEQKDIYDALERRRNEIASS-----------------QKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRL 1330
K+ KLK E+ I+ +K E + EI+K + + L + +I+E I H EQ GI E+ K P LK ++ D+ + K +S Q N ++ + ++ M D I EY S E + L ++++ K+ +K+ ++ +L LDA+S+ + ++KD+ R ++ + +K E +LN+S ++KL + + + A + KEA I ++ + I + KEL+ +N+ ++K + + K E++EN+K +
Sbjct: 1328 KFYKLKNEIKNFSIQFQKMKDDAKE-KYGEIEKLKTRYNKILEDLRSTFTDINETISGH---------EQLGISNELIKNATAYLETIKNIYKEMPNITLAASVLKDVLKYVDELNQIIKYTQSHIQSDQINNLKILKNKTIMADEINTNNKEYLNTMSTKKKEHELYIILINERMKDLQKIFRKMTKQRDNLRKKIQKLDAISKSFQDEKDLISINVREIEDLMKNLSSNHLVSKSLIIPDTLKKHVEQQLNKSSNLIKKLTKDFNFLHNA-EQAKEAYSNITRDILAVDYAINQTKKELDFNRSNMNIDSLKKLLAEFNSNKSEIVENIKNI 1650
BLAST of SMED30015457 vs. Planmine SMEST
Match: SMESG000056013.1 (SMESG000056013.1) HSP 1 Score: 50.0618 bits (118), Expect = 5.069e-6 Identity = 71/334 (21.26%), Postives = 137/334 (41.02%), Query Frame = -2
Query: 401 KYKKLKTELNTKRIELHLLKLFYNEVETNEIQKEHVKKKEELLSHENKRNEIDEQIKSHRKKVTKFNREQSGIEQEIKKCEQXXXXXXXXXXXXXPEHIKVHQKLKHLM---DKQKESKKAYESARQQHLANQEELAQLQSQM-DRIEQLKSEYELKQSQISVEKGRNLELETNQLQEYHKLKQKVAEKTSHLSAV---LDALSREYNEQKDIYDALERRRNEIASS-----------------QKRKESELNESRKRLQKLREYIDSSNRAINEQKEAEETIRVEVESATKRIEEINKELELVVTNLGEARVEKHESSRAAKKQELIENLKRL 1330
K+ KLK E+ I+ +K E + EI+K + + L + +I+E I H EQ GI E+ K P LK ++ D+ + K +S Q N ++ + ++ M D I EY S E + L ++++ K+ +K+ ++ +L LDA+S+ + ++KD+ R ++ + +K E +LN+S ++KL + + + A + KEA I ++ + I + KEL+ +N+ ++K + + K E++EN+K +
Sbjct: 1328 KFYKLKNEIKNFSIQFQKMKDDAKE-KYGEIEKLKTRYNKILEDLRSTFTDINETISGH---------EQLGISNELIKNATAYLETIKNIYKEMPNITLAASVLKDVLKYVDELNQIIKYTQSHIQSDQINNLKILKNKTIMADEINTNNKEYLNTMSTKKKEHELYIILINERMKDLQKIFRKMTKQRDNLRKKIQKLDAISKSFQDEKDLISINVREIEDLMKNLSSNHLVSKSLIIPDTLKKHVEQQLNKSSNLIKKLTKDFNFLHNA-EQAKEAYSNITRDILAVDYAINQTKKELDFNRSNMNIDSLKKLLAEFNSNKSEIVENIKNI 1650 The following BLAST results are available for this feature:
BLAST of SMED30015457 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SMED30015457 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of SMED30015457 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of SMED30015457 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SMED30015457 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SMED30015457 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SMED30015457 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SMED30015457 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SMED30015457 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SMED30015457 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of SMED30015457 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of SMED30015457 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of SMED30015457 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SMED30015457 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015457 ID=SMED30015457|Name=SMED30015457|organism=Schmidtea mediterranea sexual|type=transcript|length=1601bpback to top protein sequence of SMED30015457-orf-1 >SMED30015457-orf-1 ID=SMED30015457-orf-1|Name=SMED30015457-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=335bp MDKQKESKKAYESARQQHLANQEELAQLQSQMDRIEQLKSEYELKQSQISback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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