Poly [ADP-ribose] polymerase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015453 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 16
Homology
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Human
Match: PARP3 (poly(ADP-ribose) polymerase family member 3 [Source:HGNC Symbol;Acc:HGNC:273]) HSP 1 Score: 400.979 bits (1029), Expect = 4.898e-133 Identity = 241/506 (47.63%), Postives = 326/506 (64.43%), Query Frame = 2
Query: 137 NEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYF-VWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDA---SEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC--RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYV---ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPV--HRNITSSFGQSEYLIYQESQCRIRY 1621
+ F S AL P+ ++ + G V +DY+C LNQTNI+ NNNK+Y+IQ++Q + ++F W RWGRVGE G + K+ + EDA K F+KKF++KTKN+W RD+F S GKYTL+E+ +DE + + V V +++ P L TQ L+ IF +MF + +A + LD KK+PLGKLSK QI +GFE LE L+ + + L ELSS FYT+IPH+FG +P I + + ++ K DMLLVL DIE QAL + E + ++ P+PLD +++L L +LD + EYK+I+ Y+E T R + ++WKV++ EE F+ H + NRKLLWHGTN+AVVAAIL SGLRIMPHSGGRVG+GIYFASEN KSAGYV C G MFL EVALG+E + D+ S+ PP GF+SV+A+G TEPD + E++LDG +VVVP G+PV +S+F QSEYLIYQESQCR+RY
Sbjct: 27 DPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQS-KINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEV----PHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRY 527
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Human
Match: PARP3 (poly(ADP-ribose) polymerase family member 3 [Source:HGNC Symbol;Acc:HGNC:273]) HSP 1 Score: 400.979 bits (1029), Expect = 4.898e-133 Identity = 241/506 (47.63%), Postives = 326/506 (64.43%), Query Frame = 2
Query: 137 NEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYF-VWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDA---SEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC--RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYV---ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPV--HRNITSSFGQSEYLIYQESQCRIRY 1621
+ F S AL P+ ++ + G V +DY+C LNQTNI+ NNNK+Y+IQ++Q + ++F W RWGRVGE G + K+ + EDA K F+KKF++KTKN+W RD+F S GKYTL+E+ +DE + + V V +++ P L TQ L+ IF +MF + +A + LD KK+PLGKLSK QI +GFE LE L+ + + L ELSS FYT+IPH+FG +P I + + ++ K DMLLVL DIE QAL + E + ++ P+PLD +++L L +LD + EYK+I+ Y+E T R + ++WKV++ EE F+ H + NRKLLWHGTN+AVVAAIL SGLRIMPHSGGRVG+GIYFASEN KSAGYV C G MFL EVALG+E + D+ S+ PP GF+SV+A+G TEPD + E++LDG +VVVP G+PV +S+F QSEYLIYQESQCR+RY
Sbjct: 27 DPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQS-KINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEV----PHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRY 527
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Human
Match: PARP3 (poly(ADP-ribose) polymerase family member 3 [Source:HGNC Symbol;Acc:HGNC:273]) HSP 1 Score: 400.979 bits (1029), Expect = 5.074e-133 Identity = 241/506 (47.63%), Postives = 326/506 (64.43%), Query Frame = 2
Query: 137 NEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYF-VWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDA---SEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC--RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYV---ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPV--HRNITSSFGQSEYLIYQESQCRIRY 1621
+ F S AL P+ ++ + G V +DY+C LNQTNI+ NNNK+Y+IQ++Q + ++F W RWGRVGE G + K+ + EDA K F+KKF++KTKN+W RD+F S GKYTL+E+ +DE + + V V +++ P L TQ L+ IF +MF + +A + LD KK+PLGKLSK QI +GFE LE L+ + + L ELSS FYT+IPH+FG +P I + + ++ K DMLLVL DIE QAL + E + ++ P+PLD +++L L +LD + EYK+I+ Y+E T R + ++WKV++ EE F+ H + NRKLLWHGTN+AVVAAIL SGLRIMPHSGGRVG+GIYFASEN KSAGYV C G MFL EVALG+E + D+ S+ PP GF+SV+A+G TEPD + E++LDG +VVVP G+PV +S+F QSEYLIYQESQCR+RY
Sbjct: 34 DPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQS-KINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEV----PHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRY 534
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Human
Match: PARP2 (poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272]) HSP 1 Score: 244.973 bits (624), Expect = 1.261e-72 Identity = 183/516 (35.47%), Postives = 275/516 (53.29%), Query Frame = 2
Query: 146 DSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEM----GVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKT--KKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSRF---GVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
+S+K L KG + T A ++ G D YD MLNQTN+ NNNKYY+IQ+++ + + + VW RWGRVG+ G + A + F KKF DKTKN+W++R+ F+ V GKY +L+M +DE+ET + S S S+L Q L+ LI + ++K +TKK PLGKL+ QI G++ L+++++ I A L+E ++FYT IPHDFG R P I T + EK+ +L L DIE L+KT + PE +PLD+ ++ L L LDH+S E+K+I QY+++T + ++++++V++ E++ FR + + NR LLWHG+ ++ IL GLRI P +G G+GIYFA + KSA Y C SR G++ L+EVALG+ L + G S GK P S + + L+G+ VPLG I + G + EY++Y +Q R+RY
Sbjct: 68 ESVKALLLKGKAPVDPECTAKVGKAHVYCEG--NDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKMGQHSLVACSGNLNKAKEIFQKKFLDKTKNNWEDREKFEKVPGKYDMLQMDYATNTQDEEETKK---EESLKSPLKPESQLDLRVQELIKLICNVQAMEEMMMEMKYNTKKAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRA-LMEACNEFYTRIPHDFGLRTPPLIRTQKELSEKIQLLEALGDIEIAIKLVKTELQSPE-----------HPLDQHYRNLHCALRPLDHESYEFKVISQYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAFR--EDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSANY--CFASRLKNTGLLLLSEVALGQCNELLEANPKAEGLLQGKHSTKGLGKMAPSSAHF--VTLNGS--TVPLGPASDTGILNPDGYTLNYNEYIVYNPNQVRMRY 558
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Human
Match: PARP1 (poly(ADP-ribose) polymerase 1 [Source:HGNC Symbol;Acc:HGNC:270]) HSP 1 Score: 252.677 bits (644), Expect = 1.830e-72 Identity = 169/482 (35.06%), Postives = 265/482 (54.98%), Query Frame = 2
Query: 215 AATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYN--GKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQS-RFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNIT-SSFGQSEYLIYQESQCRIRY 1621
A L GG V + L +I N YY +Q+++ + +Y+++ WGRVG + KL +KEDA + F K +++KT N W ++ NF K+ LE+ ++E + L N + SKL K Q L+ +IF + A+ + ++D +K+PLGKLSK QI + +L E+Q +S+ + + ++L+LS++FYT+IPHDFG ++P + D+V+ K++ML L DIE +LL+ +SS +P+D ++ L D+ ++D SEE +II +YV+NT ++++I+++K++R E + ++ K + NR+LLWHG+ A IL GLRI P +G G+GIYFA KSA Y +Q G++ L EVALG L H I K P G SV GKT PD N I LDG V VPLG + + +S +EY++Y +Q ++Y
Sbjct: 543 AHVLEKGGKV---FSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTVNPG-----TKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDS-QILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSK--------DPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHAS-HISKLPKGKHSVKGLGKTTPDPSAN--ISLDG--VDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKY 1001
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Celegans
Match: parp-1 (Poly [ADP-ribose] polymerase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9N4H4]) HSP 1 Score: 199.519 bits (506), Expect = 1.928e-54 Identity = 148/475 (31.16%), Postives = 239/475 (50.32%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIE-STQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRN----VKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDG-SIVKPPAGFESVVAQGKTEPD--SKYNKEIDLDGNKVVVPLGKPV-----HRNITSSFGQSEYLIYQESQCRIRY 1621
Y L+ T++ N N YY IQ+++ + + Y+V+ WGRVG K Y+ +A +F F +KTKN W R +F+ + G ++ +E + + ++ +T S + L K + +V IF + AL ++D K+PLG+LS QI FEVL ++ + + K +++L+ S+KFYTIIPH+FG R P I + ++EK +ML L DI+ + + P S+S L +P+D ++ L ++ L +++ +I QY++NT V++I++ K++R +E F+ H I NR+LLWHG+ A IL GLRI P SG G+G+YFA KS Y N + L +VALG + L S PAGF+SV G+ P YN DG +PLG +++ +E+++Y Q +++Y
Sbjct: 477 YQATLSFTDLTQNKNSYYKIQLLKDDQRENYYVFRSWGRVGTEVGGNKHESYSNSNEAILKFQDVFHEKTKNDWIYRKHFRKMPGMFSYVETDYSEFAQITDTEITPG------SKTLLPKSVKEVVMSIFDVENMKSALKSFEMDVNKMPLGRLSHNQINLAFEVLNDISDLLVKLPIDASRILDFSNKFYTIIPHNFGMRVPEPIDSFHKIKEKNNMLNALLDIKFAYDQISGGDVPASTS-----LGIDPVDINYQKLKCIMEPLQQGCDDWNMIHQYLKNTHGATHDLKVELIDILKLNRDNESSKFKRH--IGNRRLLWHGSGKMNFAGILGQGLRIAPPEAPVSGYMFGKGVYFADMFSKSFFYCRANAKEEAYLLLCDVALGNVQQLMASKNVSRQTLPAGFQSVQGLGRQCPREIGSYNHP---DG--YTIPLGLTYMQLQGKQDVDYHLLYNEFIVYDVDQIQLKY 933
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Celegans
Match: parp-1 (Poly [ADP-ribose] polymerase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9N4H4]) HSP 1 Score: 161.77 bits (408), Expect = 2.224e-44 Identity = 113/346 (32.66%), Postives = 177/346 (51.16%), Query Frame = 2
Query: 635 IFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIE-STQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRN----VKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHD-DGSIVKPPAGFESVVAQGKTEPD--SKYNKEIDLDGNKVVVPLGKPVH-----RNITSSFGQSEYLIYQESQCRIRY 1621
IF + AL ++D K+PLG+LS QI FEVL ++ + + K +++L+ S+KFYTIIPH+FG R P I + ++EK +ML L DI+ + + P S+S L +P+D ++ L ++ L +++ +I QY++NT V++I++ K++R +E F+ H I NR+LLWHG+ A IL GLRI P SG G+G+YFA KS Y N + L +VALG + L + S PAGF+SV G+ P YN DG +PLG +++ +E+++Y Q +++Y
Sbjct: 3 IFDVENMKSALKSFEMDVNKMPLGRLSHNQINLAFEVLNDISDLLVKLPIDASRILDFSNKFYTIIPHNFGMRVPEPIDSFHKIKEKNNMLNALLDIKFAYDQISGGDVPASTS-----LGIDPVDINYQKLKCIMEPLQQGCDDWNMIHQYLKNTHGATHDLKVELIDILKLNRDNESSKFKRH--IGNRRLLWHGSGKMNFAGILGQGLRIAPPEAPVSGYMFGKGVYFADMFSKSFFYCRANAKEEAYLLLCDVALGNVQQLMASKNVSRQTLPAGFQSVQGLGRQCPREIGSYNHP---DG--YTIPLGLTYMQLQGKQDVDYHLLYNEFIVYDVDQIQLKY 336
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Celegans
Match: parp-1 (Poly [ADP-ribose] polymerase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9N4H4]) HSP 1 Score: 94.7449 bits (234), Expect = 1.590e-21 Identity = 78/257 (30.35%), Postives = 123/257 (47.86%), Query Frame = 2
Query: 902 MLLVLTDIE-STQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRN----VKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHD-DGSIVKPPAGFESVVAQGKTEPD--SKYNKEIDLDGNKVVVPLGKPVH-----RNITSSFGQSEYLIYQESQCRIRY 1621
ML L DI+ + + P S+S L +P+D ++ L ++ L +++ +I QY++NT V++I++ K++R +E F+ H I NR+LLWHG+ A IL GLRI P SG G+G+YFA KS Y N + L +VALG + L + S PAGF+SV G+ P YN DG +PLG +++ +E+++Y Q +++Y
Sbjct: 1 MLNALLDIKFAYDQISGGDVPASTS-----LGIDPVDINYQKLKCIMEPLQQGCDDWNMIHQYLKNTHGATHDLKVELIDILKLNRDNESSKFKRH--IGNRRLLWHGSGKMNFAGILGQGLRIAPPEAPVSGYMFGKGVYFADMFSKSFFYCRANAKEEAYLLLCDVALGNVQQLMASKNVSRQTLPAGFQSVQGLGRQCPREIGSYNHP---DG--YTIPLGLTYMQLQGKQDVDYHLLYNEFIVYDVDQIQLKY 245
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Celegans
Match: tank-1 (Poly [ADP-ribose] polymerase tankyrase [Source:UniProtKB/Swiss-Prot;Acc:Q9TXQ1]) HSP 1 Score: 83.9593 bits (206), Expect = 1.671e-16 Identity = 107/415 (25.78%), Postives = 183/415 (44.10%), Query Frame = 2
Query: 254 YDCMLNQTNI----DGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETS--EVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQ---NEISKNNEKTAKLL------------ELSSKFYTIIPHDFGRRRPLTITTLDTVRE---KMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHS----GGRVGRGIYFASENGKSAGYVACNQSRFGV--MFLNEVALGKEKPL 1402
+D ++N+T++ G +N +Y +Q+I+ + ++T WGR+G + P+N+ E A K+F F+ K+ N W NF+ + KY L+E D TS E+ +T +EK P + + + D+ + +A P G+ +K I K VL++L+ N I + E ++ ELS +Y++IP G +T LD V E L +IE+ LL +++ + DL + +D + + + S+ + + Q++ N+ + K+ + ++ + F N+K LWHGT + +ILK+G I P S G G GIY A KS Y C S G+ M + + ALGK + L
Sbjct: 1762 FDVLMNKTDLMYGRCGFHN-FYRMQIIKRRDAELFILFTNWGRIGSGMGEFQTTPFNSLELAAKEFKSIFKSKSGNEWAPLANFRDMPKKYRLVET---DSTPTSLAEIELTWKKNTEK-DPIR-----RMIADISDAKTLKTYASQVQMYGGSSQPFGRFTKENIEKAKLVLDKLEKNANRIKQMVEAQTGVVESNLLDAYITTSELSGDYYSLIPS--GEYEFSNLTRLDNVEEIARHRARLNRCQEIETATRLL------CAAEFRQDL--DRVDYIRSAIQCEYRLETPDSDISQRLLQWIHNSGGKQAKVKMILEISPMLSTEKFEPFVNDDNQKFLWHGTKATNLMSILKNGFLIDPPSACKNGNLFGSGIYLADSFEKSTHY--CQPSAGGINYMLVCQTALGKVRTL 2154
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Celegans
Match: tank-1 (Poly [ADP-ribose] polymerase tankyrase [Source:UniProtKB/Swiss-Prot;Acc:Q9TXQ1]) HSP 1 Score: 83.9593 bits (206), Expect = 1.796e-16 Identity = 107/415 (25.78%), Postives = 183/415 (44.10%), Query Frame = 2
Query: 254 YDCMLNQTNI----DGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETS--EVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQ---NEISKNNEKTAKLL------------ELSSKFYTIIPHDFGRRRPLTITTLDTVRE---KMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHS----GGRVGRGIYFASENGKSAGYVACNQSRFGV--MFLNEVALGKEKPL 1402
+D ++N+T++ G +N +Y +Q+I+ + ++T WGR+G + P+N+ E A K+F F+ K+ N W NF+ + KY L+E D TS E+ +T +EK P + + + D+ + +A P G+ +K I K VL++L+ N I + E ++ ELS +Y++IP G +T LD V E L +IE+ LL +++ + DL + +D + + + S+ + + Q++ N+ + K+ + ++ + F N+K LWHGT + +ILK+G I P S G G GIY A KS Y C S G+ M + + ALGK + L
Sbjct: 1800 FDVLMNKTDLMYGRCGFHN-FYRMQIIKRRDAELFILFTNWGRIGSGMGEFQTTPFNSLELAAKEFKSIFKSKSGNEWAPLANFRDMPKKYRLVET---DSTPTSLAEIELTWKKNTEK-DPIR-----RMIADISDAKTLKTYASQVQMYGGSSQPFGRFTKENIEKAKLVLDKLEKNANRIKQMVEAQTGVVESNLLDAYITTSELSGDYYSLIPS--GEYEFSNLTRLDNVEEIARHRARLNRCQEIETATRLL------CAAEFRQDL--DRVDYIRSAIQCEYRLETPDSDISQRLLQWIHNSGGKQAKVKMILEISPMLSTEKFEPFVNDDNQKFLWHGTKATNLMSILKNGFLIDPPSACKNGNLFGSGIYLADSFEKSTHY--CQPSAGGINYMLVCQTALGKVRTL 2192
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Fly
Match: Parp (gene:FBgn0010247 transcript:FBtr0113885) HSP 1 Score: 240.35 bits (612), Expect = 1.920e-68 Identity = 163/469 (34.75%), Postives = 248/469 (52.88%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT-----KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRI----MPHSGGRVGRGIYFASENGKSAGYVACN-QSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPV-HRNITSSFGQSEYLIYQESQCRIRY 1621
Y +L T+I N N YY +Q+++ + K Y+++ WGR+G N KL ++T E A + F + + DKT N ++ RDNF G+ +E+ D+ + LV + F SKL Q L+ LIF D N L + +D K+PLGKLS QI + V++E+ N + + TAKL++ +++FYT+IPH+FG + P I T + + ML L +IE +++K++ + NPLD + + L LD SEE+ I+ QYV+NT K ++KI++V+KV R+ E + F+ K + NRKLLWHG+ + IL GLRI P +G G+GIYFA KSA Y + Q+ G+M L+EVALG I K S +G+T PD I DG V +P G+ + ++ SS +EY++Y +Q I+Y
Sbjct: 536 YSVVLGLTDIQRNKNSYYKVQLLKADKKEKYWIFRSWGRIGTNIGNSKLEEFDTSESAKRNFKEIYADKTGNEYEQRDNFVKRTGRMYPIEIQYDDDQK----LVKHE---SHFFTSKLEISVQNLIKLIFDIDSMNKTLMEFHIDMDKMPLGKLSAHQIQSAYRVVKEIYN-VLECGSNTAKLIDATNRFYTLIPHNFGVQLPTLIETHQQIEDLRQMLDSLAEIEVAYSIIKSEDVSDAC--------NPLDNHYAQIKTQLVALDKNSEEFSILSQYVKNTHASTHKSYDLKIVDVFKVSRQGEARRFKPFKKLHNRKLLWHGSRLTNFVGILSHGLRIAPPEAPPTGYMFGKGIYFADMVSKSANYCCTSQQNSTGLMLLSEVALGDMMEC-TSAKYINKLSNNKHSCFGRGRTMPDPT-KSYIRSDG--VEIPYGETITDEHLKSSLLYNEYIVYDVAQVNIQY 984
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Zebrafish
Match: parp3 (poly (ADP-ribose) polymerase family, member 3 [Source:ZFIN;Acc:ZDB-GENE-030131-7435]) HSP 1 Score: 444.121 bits (1141), Expect = 4.114e-150 Identity = 259/504 (51.39%), Postives = 341/504 (67.66%), Query Frame = 2
Query: 137 NEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDAS-------EKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNI--TSSFGQSEYLIYQESQCRIRY 1621
++F S K AL S K T D + V +DYDCMLNQTNI NNNK+YVIQ++ GKY+ WTRWGRVGE+G GP + + A K F+KKF++KTKN+W +R+NF S GKYTL+E+ D D+ +EV V + D + P L ETQ L+ IF DMF A+ + LD KK+PLGKLSK QI KGFE LEE++ I K+ + +K EL++KF+TIIPH+FGR RP I+ ++ K +MLLVL DIE Q+L + E + ++ D P+P+D+ ++ L L+++D KS+EYKIIE+Y++ T + +++VW+VDR +E + FR + A+ NRKLLWHGTN+AVVAAILKSGLRIMPHSGGRVGRGIYFASEN KSAGYV + ++ G+MFLNEVALGKE + DD S+ K PAG++SV+A+G EPD + I+LDG KVVVP GK + + S F SEYLIY+ESQCRIRY
Sbjct: 30 DKFTSAKEALKATGSQVKGTRNPD--SVCHLSNAEVHEDYDCMLNQTNIGNNNNKFYVIQVLVSGGKYYCWTRWGRVGESGQNALAGP-SAADAAIKSFEKKFKEKTKNNWSDRENFVSHSGKYTLIEV---DGDQDAEVKVDSVDGGAVKVKREQNVLPCTLDAETQRLMRFIFDNDMFKEAMTSMDLDIKKMPLGKLSKQQIAKGFEALEEIEAAIKKS--ERSKFEELTNKFFTIIPHNFGRNRPPVISDDSVLQSKKEMLLVLADIEVAQSL--KAESEKAKEEMEDTVPHPVDQNYQSLKCSLNLVDKKSKEYKIIEKYLKATGQEGLTLVDVWEVDRETEAERFRENDALENRKLLWHGTNVAVVAAILKSGLRIMPHSGGRVGRGIYFASENSKSAGYVRPS-NKIGIMFLNEVALGKEYTITRDDPSLRKAPAGYDSVIARGNQEPDPSKDVFIELDGKKVVVPQGKAIKQQQYEGSHFYNSEYLIYKESQCRIRY 522
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Zebrafish
Match: parp2 (poly (ADP-ribose) polymerase 2 [Source:ZFIN;Acc:ZDB-GENE-031113-6]) HSP 1 Score: 262.692 bits (670), Expect = 9.174e-79 Identity = 182/510 (35.69%), Postives = 276/510 (54.12%), Query Frame = 2
Query: 140 EFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYV-ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
E + +KT + KG + A +++ G D YD MLNQTN+ NNNKYY+IQ+++ + Y VW RWGRVG+ G + A F KKF DKTKN W++R +F+ V GKY ++ M ED+ E V S +K P +L + Q L++LI + ++K DTKK PLGKL+ QI G+ L+ ++ E K +LL+ ++FYT IPHDFG R P I + + ++EK+ +L L+DI+ +++ S K+D +PLD ++ L+ L LD S EYK+IE+Y+++T + +++V+ V+R E+ NF + + NR LLWHG+ ++ IL GLR+ P +G G+GIYFA + KSA Y A ++ G++ L+EVALG L D + + P+G S G+T PD K K + L+G V VPLG V + G S EY++Y +Q +++Y
Sbjct: 147 ECEVVKTLVMKGKAPVDPECKAKLGKAHVYNEG--ADVYDVMLNQTNLQFNNNKYYLIQLLEDDSAKAYSVWLRWGRVGKVGQNNLVSCGANLAQAKDTFKKKFFDKTKNEWEHRASFEKVAGKYDMVFMDYSTEDKGEEKAVVPSATQKK--PCQLNSKVQSLLELICDLKAMEECVLEMKFDTKKAPLGKLTAEQIRAGYASLKRIE-ECLKKKGSNKELLDACNQFYTRIPHDFGLRTPPIIRSEEELKEKITLLETLSDIQIAVKMVQ-------SNVKSD--EHPLDRQYHSLNCQLQPLDTDSNEYKVIEKYLKSTHAPTHTDYTMTLLDVFAVEREVEKDNF--NSELQNRMLLWHGSRLSNWVGILSQGLRVAPAEAPVTGYMFGKGIYFADMSSKSANYCFASQKNNQGLLLLSEVALGDSNELLDADYNADQLPSGKHSTKGLGQTAPDPK--KSVSLNG--VTVPLGPSVKTGVGQKGGYSLLYNEYIVYNPAQIQMKY 636
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Zebrafish
Match: parp2 (poly (ADP-ribose) polymerase 2 [Source:ZFIN;Acc:ZDB-GENE-031113-6]) HSP 1 Score: 262.692 bits (670), Expect = 9.375e-79 Identity = 182/510 (35.69%), Postives = 276/510 (54.12%), Query Frame = 2
Query: 140 EFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYV-ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
E + +KT + KG + A +++ G D YD MLNQTN+ NNNKYY+IQ+++ + Y VW RWGRVG+ G + A F KKF DKTKN W++R +F+ V GKY ++ M ED+ E V S +K P +L + Q L++LI + ++K DTKK PLGKL+ QI G+ L+ ++ E K +LL+ ++FYT IPHDFG R P I + + ++EK+ +L L+DI+ +++ S K+D +PLD ++ L+ L LD S EYK+IE+Y+++T + +++V+ V+R E+ NF + + NR LLWHG+ ++ IL GLR+ P +G G+GIYFA + KSA Y A ++ G++ L+EVALG L D + + P+G S G+T PD K K + L+G V VPLG V + G S EY++Y +Q +++Y
Sbjct: 148 ECEVVKTLVMKGKAPVDPECKAKLGKAHVYNEG--ADVYDVMLNQTNLQFNNNKYYLIQLLEDDSAKAYSVWLRWGRVGKVGQNNLVSCGANLAQAKDTFKKKFFDKTKNEWEHRASFEKVAGKYDMVFMDYSTEDKGEEKAVVPSATQKK--PCQLNSKVQSLLELICDLKAMEECVLEMKFDTKKAPLGKLTAEQIRAGYASLKRIE-ECLKKKGSNKELLDACNQFYTRIPHDFGLRTPPIIRSEEELKEKITLLETLSDIQIAVKMVQ-------SNVKSD--EHPLDRQYHSLNCQLQPLDTDSNEYKVIEKYLKSTHAPTHTDYTMTLLDVFAVEREVEKDNF--NSELQNRMLLWHGSRLSNWVGILSQGLRVAPAEAPVTGYMFGKGIYFADMSSKSANYCFASQKNNQGLLLLSEVALGDSNELLDADYNADQLPSGKHSTKGLGQTAPDPK--KSVSLNG--VTVPLGPSVKTGVGQKGGYSLLYNEYIVYNPAQIQMKY 637
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Zebrafish
Match: parp2 (poly (ADP-ribose) polymerase 2 [Source:ZFIN;Acc:ZDB-GENE-031113-6]) HSP 1 Score: 247.669 bits (631), Expect = 3.489e-73 Identity = 176/515 (34.17%), Postives = 270/515 (52.43%), Query Frame = 2
Query: 140 EFDSIKTALTKG-----PSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYV-ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
E + +KT + KG P + K + H ++ TN+ NNNKYY+IQ+++ + Y VW RWGRVG+ G + A F KKF DKTKN W++R +F+ V GKY ++ M ED+ E V S +K P +L + Q L++LI + ++K DTKK PLGKL+ QI G+ L+ ++ E K +LL+ ++FYT IPHDFG R P I + + ++EK+ +L L+DI+ +++ S K+D +PLD ++ L+ L LD S EYK+IE+Y+++T + +++V+ V+R E+ NF + + NR LLWHG+ ++ IL GLR+ P +G G+GIYFA + KSA Y A ++ G++ L+EVALG L D + + P+G S G+T PD K K + L+G V VPLG V + G S EY++Y +Q +++Y
Sbjct: 148 ECEVVKTLVMKGKAPVDPECKAKLGKVIALNVLFGHKVLIA---------TNLQFNNNKYYLIQLLEDDSAKAYSVWLRWGRVGKVGQNNLVSCGANLAQAKDTFKKKFFDKTKNEWEHRASFEKVAGKYDMVFMDYSTEDKGEEKAVVPSATQKK--PCQLNSKVQSLLELICDLKAMEECVLEMKFDTKKAPLGKLTAEQIRAGYASLKRIE-ECLKKKGSNKELLDACNQFYTRIPHDFGLRTPPIIRSEEELKEKITLLETLSDIQIAVKMVQ-------SNVKSD--EHPLDRQYHSLNCQLQPLDTDSNEYKVIEKYLKSTHAPTHTDYTMTLLDVFAVEREVEKDNF--NSELQNRMLLWHGSRLSNWVGILSQGLRVAPAEAPVTGYMFGKGIYFADMSSKSANYCFASQKNNQGLLLLSEVALGDSNELLDADYNADQLPSGKHSTKGLGQTAPDPK--KSVSLNG--VTVPLGPSVKTGVGQKGGYSLLYNEYIVYNPAQIQMKY 635
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Zebrafish
Match: parp1 (poly (ADP-ribose) polymerase 1 [Source:ZFIN;Acc:ZDB-GENE-030131-3955]) HSP 1 Score: 231.106 bits (588), Expect = 4.825e-65 Identity = 154/469 (32.84%), Postives = 254/469 (54.16%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQ--YNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSR-FGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNI-TSSFGQSEYLIYQESQCRIRY 1621
Y L +I N YY +Q+++ +Y+V+ WGRVG KL + K A F +++KT N W + NF K+ LE+ ++E + L ++ A S+L K Q L+ +IF + A+ + ++D +K+PLGKLSK QI + +L E+Q ++ ++ ++ +L+LS++FYT+IPHDFG ++P ++ +D +++K+ ML L DIE +LL+ E++ K +P+D ++ L ++++D S E ++I QYV+NT + + ++K++R E + +R K + NR+LLWHG+ A IL GLRI P +G G+G+YFA KSA Y +Q+ G++ L EVALG L I K P G SV G++ PD + + L+G V +PLGK ++ NI +S +EY++Y SQ ++Y
Sbjct: 550 YSATLGLVDIVRGTNSYYKLQLLEDDVQKRYWVFRSWGRVGTTIGGNKLDKFYDKNSAMDNFCGVYEEKTGNAWAS-SNFTKYPNKFYPLEIDYGQDEEAVKKLTQSAGAK-----SQLEKPVQDLIRMIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSLLSEVQQAVADSSSESL-ILDLSNRFYTLIPHDFGMKKPPLLSNVDYIQQKVQMLDNLLDIEVAYSLLRG-GVENNEK-------DPIDINYEKLKTKIEVVDKSSHEAQLILQYVKNTHAATHNTYTLDVEEIFKIEREGEYQRYRPFKELPNRQLLWHGSRTTNYAGILSQGLRIAPPEAPVTGYMFGKGVYFADMVSKSANYCHTSQADPVGLILLGEVALGNMHEL-KKASHITKLPKGKHSVKGLGRSAPDPRAT--VSLNG--VDIPLGKGMNTNIDDTSLLYNEYIVYDVSQVNLKY 998
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Xenopus
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:NCBI gene;Acc:100145803]) HSP 1 Score: 491.5 bits (1264), Expect = 2.226e-168 Identity = 268/503 (53.28%), Postives = 337/503 (67.00%), Query Frame = 2
Query: 137 NEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGI-VVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLV---TNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT--KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPV--HRNITSSFGQSEYLIYQESQCRIRY 1621
+ F S AL K S +K ID +G V +DYDCMLNQTNI NNNK+YVIQ+I +Y+ W RWGRVGE G + KL P+ E+A K F+KKF+DKTKN W R+NF GKYT++E+ D++ + E V T +K P L K TQ L+ LIF TDMF A+ + LD KK+PLGKLSK QI KGFE L+ELQ + + K L +LSS+FYTIIPH+FGRR P I T + ++ K DMLLVL DIE Q L K + ++K P+PLD +++L DL +LD +EEYK+I+ YVENT R +KI NVW V+R +EE+ F HK I NR+LLWHGTNIAVV AILKSGLRIMPHSGGRVG+GIYFASEN KSAGYV C G+MFLNEVALG+E + DD S+ PP G++SVVA+G TEP+ ++++DLDG K+ VP G+PV + SSFGQSEYL+Y+ESQ R+RY
Sbjct: 39 DRFQSAVQAL-KAASGKKGKAKIDSSCHLSSYGDYEVYEDYDCMLNQTNIGSNNNKFYVIQLITKKNEYYCWNRWGRVGEVGQS-KLSPFPKLENAQKDFEKKFKDKTKNSWSERENFTPHPGKYTIIEVEHDDDNGSGEATVKADTVDGTVQKVRPCSLDKPTQDLISLIFSTDMFKEAMQTMNLDIKKMPLGKLSKAQIAKGFEALDELQAALDRKANKGV-LSDLSSRFYTIIPHNFGRRTPPVIDTSEVLQAKKDMLLVLADIELAQTLQADKVKKEEEEEKVQEVPHPLDVDYELLKCDLSLLDTSTEEYKVIKTYVENTGPTYRTLKIQNVWCVNRETEEERFSAHKDIENRRLLWHGTNIAVVVAILKSGLRIMPHSGGRVGKGIYFASENSKSAGYVGCTSKNLGIMFLNEVALGREHHIKMDDCSLQSPPKGYDSVVARGLTEPEPAKDRKLDLDGRKITVPQGRPVKMEKYSDSSFGQSEYLVYKESQARMRY 538
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Xenopus
Match: ENSXETT00000011320.1 (poly(ADP-ribose) polymerase 1 [Source:NCBI gene;Acc:100490557]) HSP 1 Score: 251.906 bits (642), Expect = 3.034e-72 Identity = 165/471 (35.03%), Postives = 262/471 (55.63%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQY--NGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQ---SRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNIT-SSFGQSEYLIYQESQCRIRY 1621
+ L +I N YY +Q+I++ N +Y+V+ WGRVG + KL ++KEDA F +Q+KT N W + NF K+ LE+ E++ + L + + SKLA+ Q L+ LIF + A+ + ++D +K+PLGKLSK QI + +L ++Q +S+++ + A+LL+LS++FYT+IPHDFG ++P + L+ ++ K+ ML L DIE +LL+ D + +P+D +++ + D+ ++D +SEE +II YV+NT +++++ ++K++R E + ++ K + NR+LLWHG+ A IL GLRI P +G G+GIYFA KSA Y CN + G++ L EVALG L I K P G SV G+T PD + + LDG V VPLGK NIT +S +EY++Y +Q ++Y
Sbjct: 536 FSATLGLVDITRGTNSYYKLQLIEHDRNSRYWVFRSWGRVGTVIGSNKLEEMSSKEDAIDHFLNLYQEKTGNAW-HSPNFTKYPNKFYPLEIDYGQEEDVVKKLSVGAG-----TKSKLAQPVQELIKLIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSILNQVQQAVSESSSE-ARLLDLSNQFYTLIPHDFGMKKPPLLNNLEYIQAKVQMLDNLLDIEVAYSLLRGGAD--------DGEKDPIDVKYEKIKTDIKVVDKESEESRIIRDYVKNTHAETHNAYDLEVLEIFKIEREGEYQRYKPFKQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANY--CNAMPGNPIGLILLGEVALGNMHEL-RAASHITKLPKGKHSVKGLGRTAPDP--SATVKLDG--VDVPLGKGSATNITDASLLYNEYIVYDVAQVNLKY 984
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Xenopus
Match: ENSXETT00000011326.1 (poly(ADP-ribose) polymerase 1 [Source:NCBI gene;Acc:100490557]) HSP 1 Score: 251.906 bits (642), Expect = 3.226e-72 Identity = 165/471 (35.03%), Postives = 262/471 (55.63%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQY--NGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQ---SRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNIT-SSFGQSEYLIYQESQCRIRY 1621
+ L +I N YY +Q+I++ N +Y+V+ WGRVG + KL ++KEDA F +Q+KT N W + NF K+ LE+ E++ + L + + SKLA+ Q L+ LIF + A+ + ++D +K+PLGKLSK QI + +L ++Q +S+++ + A+LL+LS++FYT+IPHDFG ++P + L+ ++ K+ ML L DIE +LL+ D + +P+D +++ + D+ ++D +SEE +II YV+NT +++++ ++K++R E + ++ K + NR+LLWHG+ A IL GLRI P +G G+GIYFA KSA Y CN + G++ L EVALG L I K P G SV G+T PD + + LDG V VPLGK NIT +S +EY++Y +Q ++Y
Sbjct: 550 FSATLGLVDITRGTNSYYKLQLIEHDRNSRYWVFRSWGRVGTVIGSNKLEEMSSKEDAIDHFLNLYQEKTGNAW-HSPNFTKYPNKFYPLEIDYGQEEDVVKKLSVGAG-----TKSKLAQPVQELIKLIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSILNQVQQAVSESSSE-ARLLDLSNQFYTLIPHDFGMKKPPLLNNLEYIQAKVQMLDNLLDIEVAYSLLRG--------GADDGEKDPIDVKYEKIKTDIKVVDKESEESRIIRDYVKNTHAETHNAYDLEVLEIFKIEREGEYQRYKPFKQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANY--CNAMPGNPIGLILLGEVALGNMHEL-RAASHITKLPKGKHSVKGLGRTAPDP--SATVKLDG--VDVPLGKGSATNITDASLLYNEYIVYDVAQVNLKY 998
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Xenopus
Match: ENSXETT00000011323.1 (poly(ADP-ribose) polymerase 1 [Source:NCBI gene;Acc:100490557]) HSP 1 Score: 251.136 bits (640), Expect = 5.416e-72 Identity = 165/471 (35.03%), Postives = 262/471 (55.63%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQY--NGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQ---SRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNIT-SSFGQSEYLIYQESQCRIRY 1621
+ L +I N YY +Q+I++ N +Y+V+ WGRVG + KL ++KEDA F +Q+KT N W + NF K+ LE+ E++ + L + + SKLA+ Q L+ LIF + A+ + ++D +K+PLGKLSK QI + +L ++Q +S+++ + A+LL+LS++FYT+IPHDFG ++P + L+ ++ K+ ML L DIE +LL+ D + +P+D +++ + D+ ++D +SEE +II YV+NT +++++ ++K++R E + ++ K + NR+LLWHG+ A IL GLRI P +G G+GIYFA KSA Y CN + G++ L EVALG L I K P G SV G+T PD + + LDG V VPLGK NIT +S +EY++Y +Q ++Y
Sbjct: 547 FSATLGLVDITRGTNSYYKLQLIEHDRNSRYWVFRSWGRVGTVIGSNKLEEMSSKEDAIDHFLNLYQEKTGNAW-HSPNFTKYPNKFYPLEIDYGQEEDVVKKLSVGAG-----TKSKLAQPVQELIKLIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSILNQVQQAVSESSSE-ARLLDLSNQFYTLIPHDFGMKKPPLLNNLEYIQAKVQMLDNLLDIEVAYSLLRG--------GADDGEKDPIDVKYEKIKTDIKVVDKESEESRIIRDYVKNTHAETHNAYDLEVLEIFKIEREGEYQRYKPFKQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANY--CNAMPGNPIGLILLGEVALGNMHEL-RAASHITKLPKGKHSVKGLGRTAPDP--SATVKLDG--VDVPLGKGSATNITDASLLYNEYIVYDVAQVNLKY 995
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Xenopus
Match: ENSXETT00000004148.1 (poly(ADP-ribose) polymerase 1 [Source:NCBI gene;Acc:100490557]) HSP 1 Score: 247.284 bits (630), Expect = 1.226e-70 Identity = 162/471 (34.39%), Postives = 257/471 (54.56%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQY--NGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQ---SRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNIT-SSFGQSEYLIYQESQCRIRY 1621
+ L +I N YY +Q+I++ N +Y+V+ WGRVG + KL ++KED KT N W + NF K+ LE+ E++ + L + + SKLA+ Q L+ LIF + A+ + ++D +K+PLGKLSK QI + +L ++Q +S+++ + A+LL+LS++FYT+IPHDFG ++P + L+ ++ K+ ML L DIE +LL+ D + +P+D +++ + D+ ++D +SEE +II YV+NT +++++ ++K++R E + ++ K + NR+LLWHG+ A IL GLRI P +G G+GIYFA KSA Y CN + G++ L EVALG L I K P G SV G+T PD + + LDG V VPLGK NIT +S +EY++Y +Q ++Y
Sbjct: 549 FSATLGLVDITRGTNSYYKLQLIEHDRNSRYWVFRSWGRVGTVIGSNKLEEMSSKED-----------KTGNAW-HSPNFTKYPNKFYPLEIDYGQEEDVVKKLSVGAG-----TKSKLAQPVQELIKLIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYSILNQVQQAVSESSSE-ARLLDLSNQFYTLIPHDFGMKKPPLLNNLEYIQAKVQMLDNLLDIEVAYSLLRGGAD--------DGEKDPIDVKYEKIKTDIKVVDKESEESRIIRDYVKNTHAETHNAYDLEVLEIFKIEREGEYQRYKPFKQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANY--CNAMPGNPIGLILLGEVALGNMHEL-RAASHITKLPKGKHSVKGLGRTAPDP--SATVKLDG--VDVPLGKGSATNITDASLLYNEYIVYDVAQVNLKY 986
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Mouse
Match: Parp3 (poly (ADP-ribose) polymerase family, member 3 [Source:MGI Symbol;Acc:MGI:1891258]) HSP 1 Score: 373.629 bits (958), Expect = 1.148e-122 Identity = 243/529 (45.94%), Postives = 327/529 (61.81%), Query Frame = 2
Query: 74 MPPKRXXXXXXXXXXXXXXXXNEFDSIKT---ALTKGPSFRKKTHTIDKFAATLFHGGIVV-DDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT----KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVA---CNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLD--GNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
M PKRKAS + + + +++ E DS ++ AL P+ + +D + GI V +DYDC LNQTNI NNNK+Y+IQ+++ ++F W RWGRVGE G + K+ + EDA K F KKF +KTKN W+ RD F + KYTL+E+ + E + + V V + P L TQ L+ IF +MF +A+ + LD KK+PLGKL+K QI +GFE LE L+ + L ELSS FYT+IPH+FGR RP I + D ++ K DMLLVL DIE Q L + ++K + P+PLD +++L L +LD EYK I+ Y++ T +C +++ +VWKV+R E F+ H + NR+LLWHGTN+AVVAAIL SGLRIMPHSGGRVG+GIYFASEN KSAGYV C + G MFL EVALGKE + DD S+ PP+GF+SV+A+G+TEPD + E++LD V +SSF QSEYLIY+ESQCR+RY
Sbjct: 1 MAPKRKASVQTEGSKKRRQGTEEEDSFRSTAEALRAAPA-DNRVIRVDPSCPFSRNPGIQVHEDYDCTLNQTNIGNNNNKFYIIQLLEEGSRFFCWNRWGRVGEVGQS-KMNHFTCLEDAKKDFKKKFWEKTKNKWEERDRFVAQPNKYTLIEVQGEAESQEAVVKVYSGPVRTVVKPCSLDPATQNLITNIFSKEMFKNAMTLMNLDVKKMPLGKLTKQQIARGFEALEALEEAMKNPTGDGQSLEELSSCFYTVIPHNFGRSRPPPINSPDVLQAKKDMLLVLADIELAQTL---QAAPGEEEEKVEEVPHPLDRDYQLLRCQLQLLDSGESEYKAIQTYLKQTGNSYRCPDLR--HVWKVNREGEGDRFQAHSKLGNRRLLWHGTNVAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVTTMHCGGHQVGYMFLGEVALGKEHHITIDDPSLKSPPSGFDSVIARGQTEPDPAQDIELELDGQPVVVPQGPPVQCPSFKSSSFSQSEYLIYKESQCRLRY 522
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Mouse
Match: Parp3 (poly (ADP-ribose) polymerase family, member 3 [Source:MGI Symbol;Acc:MGI:1891258]) HSP 1 Score: 373.629 bits (958), Expect = 1.148e-122 Identity = 243/529 (45.94%), Postives = 327/529 (61.81%), Query Frame = 2
Query: 74 MPPKRXXXXXXXXXXXXXXXXNEFDSIKT---ALTKGPSFRKKTHTIDKFAATLFHGGIVV-DDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT----KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVA---CNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLD--GNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
M PKRKAS + + + +++ E DS ++ AL P+ + +D + GI V +DYDC LNQTNI NNNK+Y+IQ+++ ++F W RWGRVGE G + K+ + EDA K F KKF +KTKN W+ RD F + KYTL+E+ + E + + V V + P L TQ L+ IF +MF +A+ + LD KK+PLGKL+K QI +GFE LE L+ + L ELSS FYT+IPH+FGR RP I + D ++ K DMLLVL DIE Q L + ++K + P+PLD +++L L +LD EYK I+ Y++ T +C +++ +VWKV+R E F+ H + NR+LLWHGTN+AVVAAIL SGLRIMPHSGGRVG+GIYFASEN KSAGYV C + G MFL EVALGKE + DD S+ PP+GF+SV+A+G+TEPD + E++LD V +SSF QSEYLIY+ESQCR+RY
Sbjct: 1 MAPKRKASVQTEGSKKRRQGTEEEDSFRSTAEALRAAPA-DNRVIRVDPSCPFSRNPGIQVHEDYDCTLNQTNIGNNNNKFYIIQLLEEGSRFFCWNRWGRVGEVGQS-KMNHFTCLEDAKKDFKKKFWEKTKNKWEERDRFVAQPNKYTLIEVQGEAESQEAVVKVYSGPVRTVVKPCSLDPATQNLITNIFSKEMFKNAMTLMNLDVKKMPLGKLTKQQIARGFEALEALEEAMKNPTGDGQSLEELSSCFYTVIPHNFGRSRPPPINSPDVLQAKKDMLLVLADIELAQTL---QAAPGEEEEKVEEVPHPLDRDYQLLRCQLQLLDSGESEYKAIQTYLKQTGNSYRCPDLR--HVWKVNREGEGDRFQAHSKLGNRRLLWHGTNVAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVTTMHCGGHQVGYMFLGEVALGKEHHITIDDPSLKSPPSGFDSVIARGQTEPDPAQDIELELDGQPVVVPQGPPVQCPSFKSSSFSQSEYLIYKESQCRLRY 522
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Mouse
Match: Parp3 (poly (ADP-ribose) polymerase family, member 3 [Source:MGI Symbol;Acc:MGI:1891258]) HSP 1 Score: 369.777 bits (948), Expect = 4.098e-121 Identity = 245/536 (45.71%), Postives = 328/536 (61.19%), Query Frame = 2
Query: 74 MPPKRXXXXXXXXXXXXXXXXNEFDSIKT---ALTKGPSFRKKTHTIDKFAATLFHGGIVV-DDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVT-------NSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT----KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVA---CNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLD--GNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
M PKRKAS + + + +++ E DS ++ AL P+ + +D + GI V +DYDC LNQTNI NNNK+Y+IQ+++ ++F W RWGRVGE G + K+ + EDA K F KKF +KTKN W+ RD F + KYTL+E V+ E E+ E +V + P L TQ L+ IF +MF +A+ + LD KK+PLGKL+K QI +GFE LE L+ + L ELSS FYT+IPH+FGR RP I + D ++ K DMLLVL DIE Q L + ++K + P+PLD +++L L +LD EYK I+ Y++ T +C +++ +VWKV+R E F+ H + NR+LLWHGTN+AVVAAIL SGLRIMPHSGGRVG+GIYFASEN KSAGYV C + G MFL EVALGKE + DD S+ PP+GF+SV+A+G+TEPD + E++LD V +SSF QSEYLIY+ESQCR+RY
Sbjct: 1 MAPKRKASVQTEGSKKRRQGTEEEDSFRSTAEALRAAPA-DNRVIRVDPSCPFSRNPGIQVHEDYDCTLNQTNIGNNNNKFYIIQLLEEGSRFFCWNRWGRVGEVGQS-KMNHFTCLEDAKKDFKKKFWEKTKNKWEERDRFVAQPNKYTLIE--VQGEAESQEAVVKALSPQVYSGPVRTVVKPCSLDPATQNLITNIFSKEMFKNAMTLMNLDVKKMPLGKLTKQQIARGFEALEALEEAMKNPTGDGQSLEELSSCFYTVIPHNFGRSRPPPINSPDVLQAKKDMLLVLADIELAQTL---QAAPGEEEEKVEEVPHPLDRDYQLLRCQLQLLDSGESEYKAIQTYLKQTGNSYRCPDLR--HVWKVNREGEGDRFQAHSKLGNRRLLWHGTNVAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVTTMHCGGHQVGYMFLGEVALGKEHHITIDDPSLKSPPSGFDSVIARGQTEPDPAQDIELELDGQPVVVPQGPPVQCPSFKSSSFSQSEYLIYKESQCRLRY 527
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Mouse
Match: Parp2 (poly (ADP-ribose) polymerase family, member 2 [Source:MGI Symbol;Acc:MGI:1341112]) HSP 1 Score: 248.44 bits (633), Expect = 2.639e-74 Identity = 184/518 (35.52%), Postives = 275/518 (53.09%), Query Frame = 2
Query: 146 DSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVV---DDYDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEM----GVKDEDETSEVLVTNSDASEKFSP-SKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT-----KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSRF---GVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
DS+KT L KG K + AA L + D YD MLNQTN+ NNNKYY+IQ+++ + + + VW RWGRVG+ G + A + F KKF DKTKN+W++R+NF+ V GKY +L+M +DE +T E E P S+L Q L+ LI + ++K DTK+ PLGKL+ QI G++ L+++++ I A L+E ++FYT IPHDFG P I T + +K+ +L L DIE L+K S +Q + +PLD+ ++ L L LDH+S E+K+I QY+++T K + +++V++V++ E++ FR + + NR LLWHG+ ++ IL GLR+ P +G G+GIYFA + KSA Y C SR G++ L+EVALG+ L + G S GK P + I L+G+ VPLG I + G + E+++Y +Q R+RY
Sbjct: 61 DSVKTLLLKG-----KAPVDPECAAKLGKAHVYCEGDDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKTGQHSLVTCSGDLNKAKEIFQKKFLDKTKNNWEDRENFEKVPGKYDMLQMDYAASTQDESKTKE--------EETLKPESQLDLRVQELLKLICNVQTMEEMMIEMKYDTKRAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRA-LVEACNEFYTRIPHDFGLSIPPVIRTEKELSDKVKLLEALGDIEIALKLVK------SERQGLE---HPLDQHYRNLHCALRPLDHESNEFKVISQYLQSTHAPTHKDYTMTLLDVFEVEKEGEKEAFR--EDLPNRMLLWHGSRLSNWVGILSHGLRVAPPEAPITGYMFGKGIYFADMSSKSANY--CFASRLKNTGLLLLSEVALGQCNELLEANPKAQGLLRGKHSTKGMGKMAPSPAHF--ITLNGS--TVPLGPASDTGILNPEGYTLNYNEFIVYSPNQVRMRY 547
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Mouse
Match: Parp1 (poly (ADP-ribose) polymerase family, member 1 [Source:MGI Symbol;Acc:MGI:1340806]) HSP 1 Score: 246.128 bits (627), Expect = 3.030e-70 Identity = 164/486 (33.74%), Postives = 266/486 (54.73%), Query Frame = 2
Query: 203 IDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYN--GKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQS-RFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNIT-SSFGQSEYLIYQESQCRIRY 1621
++ A L GG V + L +I N YY +Q+++ + +Y+++ WGRVG + KL +KEDA + F K +++KT N W ++ NF K+ LE+ ++E + L + SKL K Q LV +IF + AL + ++D +K+PLGKLS+ QI + +L E+Q +S+ + ++ ++L+LS++FYT+IPHDFG ++P + D+V+ K++ML L DIE +LL+ +SS +P+D ++ L D+ ++D SEE ++I +YV+NT ++++I+++K++R E + ++ + + NR+LLWHG+ A IL GLRI P +G G+GIYFA KSA Y +Q G++ L EVALG L H I K P G SV GKT PD + I L+G V VPLG + + + +EY++Y +Q ++Y
Sbjct: 539 LEHSAHVLEKGGKV---FSATLGLVDIVKGTNSYYKLQLLEDDKESRYWIFRSWGRVGTVIGSNKLEQMPSKEDAVEHFMKLYEEKTGNAWHSK-NFTKYPKKFYPLEIDYGQDEEAVKKLTVKPG-----TKSKLPKPVQELVGMIFDVESMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQAVSQGSSES-QILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSK--------DPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHAS-HISKLPKGKHSVKGLGKTTPDP--SASITLEG--VEVPLGTGIPSGVNDTCLLYNEYIVYDIAQVNLKY 1001
BLAST of Poly [ADP-ribose] polymerase vs. UniProt/SwissProt
Match: sp|Q9Y6F1|PARP3_HUMAN (Protein mono-ADP-ribosyltransferase PARP3 OS=Homo sapiens OX=9606 GN=PARP3 PE=1 SV=4) HSP 1 Score: 400.979 bits (1029), Expect = 2.352e-132 Identity = 241/506 (47.63%), Postives = 326/506 (64.43%), Query Frame = 2
Query: 137 NEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYF-VWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDA---SEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC--RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYV---ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPV--HRNITSSFGQSEYLIYQESQCRIRY 1621
+ F S AL P+ ++ + G V +DY+C LNQTNI+ NNNK+Y+IQ++Q + ++F W RWGRVGE G + K+ + EDA K F+KKF++KTKN+W RD+F S GKYTL+E+ +DE + + V V +++ P L TQ L+ IF +MF + +A + LD KK+PLGKLSK QI +GFE LE L+ + + L ELSS FYT+IPH+FG +P I + + ++ K DMLLVL DIE QAL + E + ++ P+PLD +++L L +LD + EYK+I+ Y+E T R + ++WKV++ EE F+ H + NRKLLWHGTN+AVVAAIL SGLRIMPHSGGRVG+GIYFASEN KSAGYV C G MFL EVALG+E + D+ S+ PP GF+SV+A+G TEPD + E++LDG +VVVP G+PV +S+F QSEYLIYQESQCR+RY
Sbjct: 27 DPFRSTAEALKAIPAEKRIIRVDPTCPLSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNRWGRVGEVGQS-KINHFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPVRTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEALEALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIELAQALQAVSEQEKTVEEV----PHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCPTLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARGHTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRY 527
BLAST of Poly [ADP-ribose] polymerase vs. UniProt/SwissProt
Match: sp|Q3ULW8|PARP3_MOUSE (Protein mono-ADP-ribosyltransferase PARP3 OS=Mus musculus OX=10090 GN=Parp3 PE=2 SV=1) HSP 1 Score: 369.777 bits (948), Expect = 2.867e-120 Identity = 245/536 (45.71%), Postives = 328/536 (61.19%), Query Frame = 2
Query: 74 MPPKRXXXXXXXXXXXXXXXXNEFDSIKT---ALTKGPSFRKKTHTIDKFAATLFHGGIVV-DDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVT-------NSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT----KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVA---CNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLD--GNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
M PKRKAS + + + +++ E DS ++ AL P+ + +D + GI V +DYDC LNQTNI NNNK+Y+IQ+++ ++F W RWGRVGE G + K+ + EDA K F KKF +KTKN W+ RD F + KYTL+E V+ E E+ E +V + P L TQ L+ IF +MF +A+ + LD KK+PLGKL+K QI +GFE LE L+ + L ELSS FYT+IPH+FGR RP I + D ++ K DMLLVL DIE Q L + ++K + P+PLD +++L L +LD EYK I+ Y++ T +C +++ +VWKV+R E F+ H + NR+LLWHGTN+AVVAAIL SGLRIMPHSGGRVG+GIYFASEN KSAGYV C + G MFL EVALGKE + DD S+ PP+GF+SV+A+G+TEPD + E++LD V +SSF QSEYLIY+ESQCR+RY
Sbjct: 1 MAPKRKASVQTEGSKKRRQGTEEEDSFRSTAEALRAAPA-DNRVIRVDPSCPFSRNPGIQVHEDYDCTLNQTNIGNNNNKFYIIQLLEEGSRFFCWNRWGRVGEVGQS-KMNHFTCLEDAKKDFKKKFWEKTKNKWEERDRFVAQPNKYTLIE--VQGEAESQEAVVKALSPQVYSGPVRTVVKPCSLDPATQNLITNIFSKEMFKNAMTLMNLDVKKMPLGKLTKQQIARGFEALEALEEAMKNPTGDGQSLEELSSCFYTVIPHNFGRSRPPPINSPDVLQAKKDMLLVLADIELAQTL---QAAPGEEEEKVEEVPHPLDRDYQLLRCQLQLLDSGESEYKAIQTYLKQTGNSYRCPDLR--HVWKVNREGEGDRFQAHSKLGNRRLLWHGTNVAVVAAILTSGLRIMPHSGGRVGKGIYFASENSKSAGYVTTMHCGGHQVGYMFLGEVALGKEHHITIDDPSLKSPPSGFDSVIARGQTEPDPAQDIELELDGQPVVVPQGPPVQCPSFKSSSFSQSEYLIYKESQCRLRY 527
BLAST of Poly [ADP-ribose] polymerase vs. UniProt/SwissProt
Match: sp|Q5Z8Q9|PRP2A_ORYSJ (Poly [ADP-ribose] polymerase 2-A OS=Oryza sativa subsp. japonica OX=39947 GN=PARP2-A PE=3 SV=2) HSP 1 Score: 271.552 bits (693), Expect = 4.137e-81 Identity = 175/471 (37.15%), Postives = 257/471 (54.56%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYN--GKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFG--RRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYV-ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKP-VHRNITSSFGQSEYLIYQESQCRIRY 1621
YD +NQTN+ NNNK+Y+IQ ++ + G + V+ RWGRVG G GP++++E A +F+ KF KT NHW +R +F+ KYT LEM + D + V+ S +++ +KL + LI M + ++ ++ KLPLGKLSK I KG++VL+ + N IS+ + + +L +L+ +FYT+IPHDFG + R I T ++ K++M+ L +IE + TK E S + D PL R+K L D L+ SEEY +I+ Y+ NT + V ++ ++KV R E + F+ NR LLWHG+ + A IL GLRI P +G G+G+YFA KSA Y A R GV+ L EVALG+ L + D P G S G+TEP++ +K D DG VVVPLGKP + S +E+++Y Q R+RY
Sbjct: 195 YDATMNQTNVGDNNNKFYIIQALESDAGGSFMVYNRWGRVGARGQDKLHGPFSSREQAIYEFEGKFHGKTNNHWSDRKSFECYARKYTWLEMDYGEADRETNKKVSPS--TDQIKETKLETRIASFISLICNISMMKQQMVEIGYNSDKLPLGKLSKSTIFKGYDVLKRISNVISRADRR--QLEQLTGEFYTVIPHDFGFKKMREFIIDTPQKLKAKLEMVEALGEIE-----IATKLLEDDSTDQDD----PLYARYKQLSCDFTPLEVGSEEYSMIKTYLANTHGKTHTSYTVDVVQIFKVSRHGEMERFQKFATAGNRMLLWHGSRLTNWAGILSQGLRIAPPEAPVTGYMFGKGVYFADMFSKSANYCYASEACRSGVLLLCEVALGEMNELLNADYDANNLPKGKLSTKGVGQTEPNTAESKITD-DG--VVVPLGKPKAEPSKRGSLLYNEFIVYNVDQIRMRY 649
BLAST of Poly [ADP-ribose] polymerase vs. UniProt/SwissProt
Match: sp|O50017|PARP2_MAIZE (Poly [ADP-ribose] polymerase 2 OS=Zea mays OX=4577 GN=PARP2 PE=2 SV=1) HSP 1 Score: 260.381 bits (664), Expect = 6.198e-77 Identity = 176/471 (37.37%), Postives = 252/471 (53.50%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYN--GKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRR--RPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYV-ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHR-NITSSFGQSEYLIYQESQCRIRY 1621
YD LNQTN+ NNNK+Y+IQ+++ + G + V+ RWGRVG G GP T++ A +F+ KF +KT NHW +R NFK KYT LEM D ET E + +++ +KL + LI M + ++ + +KLPLGKL K I+KG+ VL+ + + ISK + + L +L+ +FYT+IPHDFG R R I T ++ K++M+ L +IE LL+ + SS Q +PL R+K L D L+ S+EY +I+ Y+ NT + V I+ ++KV R E + F+ + NR LLWHG+ ++ A IL GLRI P +G G+G+YFA KSA Y A R GV+ L EVALG L + D P G G+T P+ +K D DG VVVPLG+P + +EY++Y Q R+RY
Sbjct: 190 YDATLNQTNVGDNNNKFYIIQVLESDAGGSFMVYNRWGRVGVRGQDKLHGPSPTRDQAIYEFEGKFHNKTNNHWSDRKNFKCYAKKYTWLEM---DYGET-EKEIEKGSITDQIKETKLETRIAQFISLICNISMMKQRMVEIGYNAEKLPLGKLRKATILKGYHVLKRISDVISKADRR--HLEQLTGEFYTVIPHDFGFRKMREFIIDTPQKLKAKLEMVEALGEIEIATKLLE----DDSSDQD-----DPLYARYKQLHCDFTPLEADSDEYSMIKSYLRNTHGKTHSGYTVDIVQIFKVSRHGETERFQKFASTRNRMLLWHGSRLSNWAGILSQGLRIAPPEAPVTGYMFGKGVYFADMFSKSANYCYASEACRSGVLLLCEVALGDMNELLNADYDANNLPKGKLRSKGVGQTAPNMVESKVAD-DG--VVVPLGEPKQEPSKRGGLLYNEYIVYNVDQIRMRY 642
BLAST of Poly [ADP-ribose] polymerase vs. UniProt/SwissProt
Match: sp|Q11207|PARP2_ARATH (Poly [ADP-ribose] polymerase 2 OS=Arabidopsis thaliana OX=3702 GN=PARP2 PE=2 SV=1) HSP 1 Score: 253.447 bits (646), Expect = 1.335e-74 Identity = 171/475 (36.00%), Postives = 253/475 (53.26%), Query Frame = 2
Query: 248 DDYDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVL--VTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRR--PLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQ-SRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSS-FGQSEYLIYQESQCRIRY 1621
D YD +LNQTN+ NNNK++V+Q+++ + K Y V+TRWGRVG G + GPY++ + A + F KF DKTKN+W +R F YT LEM E+ S V + +S + K SKL + LI M + ++ + KLPLGK+SK I KG+EVL+ + I + + +L ELS +FYT+IPHDFG ++ I T +++K++M+ L +IE LL L+ +PL ++ L+ L + + SEE+ ++ Y+ENT + V+I +++ R E F+ + NR LLWHG+ + A IL GLRI P +G G+G+YFA KSA Y N + GV+ L EVALG L + D + P G S GKT P+ + ++ DG VVVPLGKPV R+ + +EY++Y Q ++RY
Sbjct: 167 DVYDAILNQTNVRDNNNKFFVLQVLESDSKKTYMVYTRWGRVGVKGQSKLDGPYDSWDRAIEIFTNKFNDKTKNYWSDRKEFIPHPKSYTWLEMDYGKEENDSPVNNDIPSSSSEVKPEQSKLDTRVAKFISLICNVSMMAQHMMEIGYNANKLPLGKISKSTISKGYEVLKRISEVIDRYDR--TRLEELSGEFYTVIPHDFGFKKMSQFVIDTPQKLKQKIEMVEALGEIELATKLLSV---------DPGLQDDPLYYHYQQLNCGLTPVGNDSEEFSMVANYMENTHAKTHSGYTVEIAQLFRASRAVEADRFQQFSSSKNRMLLWHGSRLTNWAGILSQGLRIAPPEAPVTGYMFGKGVYFADMFSKSANYCYANTGANDGVLLLCEVALGDMNELLYSDYNADNLPPGKLSTKGVGKTAPNPSEAQTLE-DG--VVVPLGKPVERSCSKGMLLYNEYIVYNVEQIKMRY 627
BLAST of Poly [ADP-ribose] polymerase vs. TrEMBL
Match: C3Z2P3 (Poly [ADP-ribose] polymerase (Fragment) OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_203655 PE=4 SV=1) HSP 1 Score: 504.212 bits (1297), Expect = 1.599e-170 Identity = 271/494 (54.86%), Postives = 343/494 (69.43%), Query Frame = 2
Query: 164 LTKGPSFRKKTHTIDKFAATLFHGGI-VVDDYDCMLNQTNIDGNNNKYYVIQMIQYNG--KYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTK---CRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHR--NITSSFGQSEYLIYQESQCRIRY 1621
L K S KK + +D + FH V DDYDCMLNQTNI NNNKYYVIQ+++ G +YFVW RWGRVGE G GP++ E A K F+KKF+DKTKN W R +F V GKYTLLEM + +E + + K PS L TQ L+ LIF DMF +A++++D +K+PLGKLSK QI KGFEVL+E++ E+ + +T++L ELSS+FYT+IPHDFGR+ P I + +R+KMDMLLVL DIE QA+ K K + S + D+K +PLD + +L+ L+++ SEE+K+IE+Y E TK R+ KI+NVWKVDR E F+ H + NRKLLWHGTN+AVVAAILK+GLRIMPHSGGRVGRGIYFASEN KSAGYV C G+MFLNEVALGKE + DD S+ KPPAGF+SVVA G+ EPD K N + LDG VVVP G+P+++ +SSF QSEYL+Y+E+QCRIRY
Sbjct: 22 LKKSASPTKKVYKVDSYCP--FHNCAEVQDDYDCMLNQTNIGHNNNKYYVIQLLRTIGISRYFVWNRWGRVGEPGQNAMKGPWDL-ETAKKDFEKKFKDKTKNDWSKRGSFVPVPGKYTLLEMDTDETEEDEQDTAEKVRRTRKVLPSSLNSPTQSLIKLIFDNDMFKEQMAKMEIDVRKMPLGKLSKSQIAKGFEVLDEIEEELKMS--RTSRLTELSSRFYTVIPHDFGRKVPPVINDQEKLRKKMDMLLVLGDIEIAQAMQKDKDKDDGS-EAMDIK-HPLDLNYDLLNCGLELVKPSSEEFKVIEKYTEATKYSGWRDPKILNVWKVDRGGEGDRFQEHDHLENRKLLWHGTNVAVVAAILKTGLRIMPHSGGRVGRGIYFASENSKSAGYVGCASGNVGIMFLNEVALGKENRITRDDSSLTKPPAGFDSVVAVGRKEPDPKKNTTMKLDGRTVVVPQGQPINQTEGQSSSFSQSEYLVYKENQCRIRY 508
BLAST of Poly [ADP-ribose] polymerase vs. TrEMBL
Match: H3BCR5 (Poly [ADP-ribose] polymerase OS=Latimeria chalumnae OX=7897 GN=PARP3 PE=4 SV=1) HSP 1 Score: 491.886 bits (1265), Expect = 1.662e-165 Identity = 278/526 (52.85%), Postives = 352/526 (66.92%), Query Frame = 2
Query: 74 MPPKRXXXXXXXXXXXXXXXXNE--FDSIKTALTKGPSFRKKTHTIDKFAATLFH--GGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASE--KFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC--RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRN--ITSSFGQSEYLIYQESQCRIRY 1621
MPPKRKA++ K+A K E F S AL P + KT ID A +L H V +DYDCMLNQTNI NNNK+Y+IQ+I+ NG YF W RWGRVGE G + KL P N+ + A K F+KKF+DKTKN W NR+NF + GKYT++E+ DE E EV + D + K P L TQ LV LIF DMF A+ + LD KK+PLGKLSK QI KGFE LEE++ + K K +L EL SKFYTIIPH+FGR RP I+T + ++ K DMLLVL DI +AL K ES+ K+ + P+PLDE +++L +L +L+ EEYKII++Y+E T R +K++N WKV+R E + F H + NR+LLWHGT+IAV+AAILKSGLRIMPHSGGRVGRGIYFASENGKS+ YV + G+MFL EVALGKE + DD S+ P G+ VVA+G TEPD + I +DG KVVVP GKP+ ++ +S+F QSEY+IY+E+QCRIRY
Sbjct: 1 MPPKRKAASSSKRAKKGKVEPQEDTFRSTVEALKAAPKEKVKTK-IDS-ACSLSHDQASQVYEDYDCMLNQTNIGHNNNKFYIIQLIEKNGAYFCWNRWGRVGEVGQS-KLSPANSLDAAKKDFEKKFKDKTKNDWSNRENFTAHAGKYTMIEVEAGDEGEV-EVKIDAVDGGKLKKVRPCTLNNPTQDLVSLIFNNDMFKDAMETMNLDVKKMPLGKLSKQQIAKGFEALEEIEASLQKKGSKK-QLEELCSKFYTIIPHNFGRMRPPVISTTEVIQAKKDMLLVLADIVLAKALQAEK--ESNKKEDIEEVPHPLDEDYQLLKCELSLLEPDIEEYKIIKKYIEATGSTHRTLKLLNAWKVNREGESERFSTHDDLDNRRLLWHGTSIAVIAAILKSGLRIMPHSGGRVGRGIYFASENGKSSAYVGTTSNSIGIMFLGEVALGKEYHITTDDSSLRAAPPGYNCVVARGCTEPDPSKDTAITVDGKKVVVPQGKPIRQDKFASSNFSQSEYVIYKENQCRIRY 519
BLAST of Poly [ADP-ribose] polymerase vs. TrEMBL
Match: B1WBK7 (Poly [ADP-ribose] polymerase OS=Xenopus tropicalis OX=8364 GN=parp3 PE=2 SV=1) HSP 1 Score: 491.5 bits (1264), Expect = 3.495e-165 Identity = 268/503 (53.28%), Postives = 337/503 (67.00%), Query Frame = 2
Query: 137 NEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGI-VVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLV---TNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT--KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPV--HRNITSSFGQSEYLIYQESQCRIRY 1621
+ F S AL K S +K ID +G V +DYDCMLNQTNI NNNK+YVIQ+I +Y+ W RWGRVGE G + KL P+ E+A K F+KKF+DKTKN W R+NF GKYT++E+ D++ + E V T +K P L K TQ L+ LIF TDMF A+ + LD KK+PLGKLSK QI KGFE L+ELQ + + K L +LSS+FYTIIPH+FGRR P I T + ++ K DMLLVL DIE Q L K + ++K P+PLD +++L DL +LD +EEYK+I+ YVENT R +KI NVW V+R +EE+ F HK I NR+LLWHGTNIAVV AILKSGLRIMPHSGGRVG+GIYFASEN KSAGYV C G+MFLNEVALG+E + DD S+ PP G++SVVA+G TEP+ ++++DLDG K+ VP G+PV + SSFGQSEYL+Y+ESQ R+RY
Sbjct: 39 DRFQSAVQAL-KAASGKKGKAKIDSSCHLSSYGDYEVYEDYDCMLNQTNIGSNNNKFYVIQLITKKNEYYCWNRWGRVGEVGQS-KLSPFPKLENAQKDFEKKFKDKTKNSWSERENFTPHPGKYTIIEVEHDDDNGSGEATVKADTVDGTVQKVRPCSLDKPTQDLISLIFSTDMFKEAMQTMNLDIKKMPLGKLSKAQIAKGFEALDELQAALDRKANKGV-LSDLSSRFYTIIPHNFGRRTPPVIDTSEVLQAKKDMLLVLADIELAQTLQADKVKKEEEEEKVQEVPHPLDVDYELLKCDLSLLDTSTEEYKVIKTYVENTGPTYRTLKIQNVWCVNRETEEERFSAHKDIENRRLLWHGTNIAVVVAILKSGLRIMPHSGGRVGKGIYFASENSKSAGYVGCTSKNLGIMFLNEVALGREHHIKMDDCSLQSPPKGYDSVVARGLTEPEPAKDRKLDLDGRKITVPQGRPVKMEKYSDSSFGQSEYLVYKESQARMRY 538
BLAST of Poly [ADP-ribose] polymerase vs. TrEMBL
Match: G1KLC9 (Poly [ADP-ribose] polymerase OS=Anolis carolinensis OX=28377 GN=PARP3 PE=4 SV=2) HSP 1 Score: 489.574 bits (1259), Expect = 2.235e-164 Identity = 264/506 (52.17%), Postives = 341/506 (67.39%), Query Frame = 2
Query: 137 NEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGG--IVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSD-----ASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC--RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGK--PVHRNITSSFGQSEYLIYQESQCRIRY 1621
+ F S AL P + K+ ID G + +DYDCMLNQTNI NNNK+Y+IQ+I+ NGKY W RWGRVGE G + KL + + E A K F+KKF+DKTKN+W +RDNF GKYTL+E+ DE++ ++ +S A +K P L K TQ LV LIF DMF A+ + +D KK+PLGKLSK QI KGFE LE ++ + + + KL ELSS+FYTIIPH+FGR RP I T + ++ K DMLLVL DIE Q+L KK E +++ P+PLD+ + +L L ++D +YK+I Y+E T C R + ++N+WKV+R SE F+IH + NR+LLWHGTNIAVVAAILKSGLRIMPHSGGRVG+G+YFASEN KSAGYV + G+MFLNEVALGKE + DD S+ KPP G++SV+A G+TEPD ++KE+ LDG KV++ GK P+ + +SSF QSEYLIYQESQCRIRY
Sbjct: 33 DSFHSTLVALKAAPKEKLKS-KIDSACWLSSSAGDAKIYEDYDCMLNQTNIGHNNNKFYIIQLIEENGKYSCWNRWGRVGEAGQS-KLNSFPSLEAAKKDFEKKFRDKTKNNWADRDNFVCHDGKYTLIEVQQGDEEDQEVIVKVDSTDGVKPAKQKIRPCTLDKPTQELVSLIFSNDMFKDAMQTMNIDVKKMPLGKLSKQQIAKGFEALEAIETTLQEQSYSQKKLEELSSRFYTIIPHNFGRCRPPAINTQEIIQAKKDMLLVLADIELAQSLQAQKKEEEEEEEEMKEVPHPLDKDYGLLKCQLTLVDPSVADYKLIVNYIEKTGCSYRKLNVMNIWKVNRESENSRFKIHDHLQNRRLLWHGTNIAVVAAILKSGLRIMPHSGGRVGKGLYFASENSKSAGYVGTTSKQVGIMFLNEVALGKEHRITCDDSSLRKPPDGYDSVLACGRTEPDPAHDKELILDGKKVLISQGKPIPIKQYESSSFSQSEYLIYQESQCRIRY 536
BLAST of Poly [ADP-ribose] polymerase vs. TrEMBL
Match: V3ZW97 (Poly [ADP-ribose] polymerase OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_214893 PE=4 SV=1) HSP 1 Score: 483.026 bits (1242), Expect = 4.835e-162 Identity = 261/484 (53.93%), Postives = 341/484 (70.45%), Query Frame = 2
Query: 185 RKKTHTIDKFAATLFH-GGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLK---PNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
+KK+H IDK + V+DDY+CMLNQTNI NNNK+Y+IQ+I+ NG+Y W RWGRVGE G K +TK +A K F+KKFQDKTKN W NRD+F++ GKYT+++M DE+E + + + SKL K TQ V LIF DMF ++ + +D KK+PLGKLSK QI KGFEVL+E++ + N +K+ L+ELSS+FYT IPHDFGRR P I + +R+KMDML+VL DIE Q + K K K+ A +K PNP+D ++ML +L++L+ KSEEYK+IE Y T+ R+VK+ +VWK DR ++ F+ H + NRKLLWHGTNIAVVAAILK+GLRIMPHSGGRVG+GIYFASENGKSAGYV+CN ++ G+MFL+EVALGK+ + DD ++ P GF+SV+A+G TEPD K +K I ++G KVV+P GKP SSF QSEYL+Y+ESQ R+RY
Sbjct: 48 KKKSHAIDKACYLASNTNARVLDDYNCMLNQTNIGHNNNKFYIIQVIETNGQYCAWNRWGRVGEMG-DFKDMMCSTKAEAIKLFEKKFQDKTKNKWANRDSFEAKTGKYTMIDMAGDDEEEDEVDAPKVDLSGKTIAESKLDKVTQKFVSLIFDLDMFKESMKKFDIDVKKMPLGKLSKTQIAKGFEVLDEIEEVL--NKKKSGNLVELSSRFYTAIPHDFGRRVPPKIDNAEALRQKMDMLMVLADIEIAQEMTKEK-----DKKMATVKGEVPNPIDVNYEMLKCNLELLNPKSEEYKLIETYTNETQGYRSVKLQHVWKCDREGDDDRFKAHDKLGNRKLLWHGTNIAVVAAILKTGLRIMPHSGGRVGKGIYFASENGKSAGYVSCN-NKTGIMFLSEVALGKQNVILRDDHTLKAAPKGFDSVLAKGNTEPDCKKDKTITINGKKVVIPQGKPTKFATGSSFSQSEYLVYKESQNRLRY 522
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Cavefish
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:NCBI gene;Acc:103034813]) HSP 1 Score: 429.098 bits (1102), Expect = 2.239e-144 Identity = 253/469 (53.94%), Postives = 324/469 (69.08%), Query Frame = 2
Query: 242 VVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDA-----SEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGK----PVHRNITSSFGQSEYLIYQESQCRIRY 1621
V +DYDCMLNQTNI NNNK+YVIQ++ G Y+ WTRWGRVGE+G GP N + A K F+KKF+DKTKN+W +R+NF S GKYTL+E+ D D+ +EV V D + P L TQ L+ IF DMF A+ + LD KK+PLGKLSK QI KGFE LEE++ KN + + L ELSSKF+TIIPH+FGR RP I T + + K +MLLVL DIE Q+L + E + ++ + P+P+D+ ++ L +L IL KS+E+KIIE+Y++ T + I++VW+VDR E + F+ + A+ NRKLLWHGTN+AVVAAILKSGLRIMPHSGGRVG+GIYFASEN KSAGYV + +R G+MFLNEVALG+E + DD ++ K PAG++SVVA+G+ EPDS + IDLDG KV VP GK P + S F SEYLIY+ESQCRIRY
Sbjct: 61 VHEDYDCMLNQTNIGNNNNKFYVIQVLVDGGTYYCWTRWGRVGESGQNNLAGPTNA-DAAIKNFEKKFKDKTKNNWSDRENFVSHSGKYTLIEV---DGDQDAEVKVDAVDGRAAEVKKNILPCTLDDPTQRLIKFIFNNDMFKEAMENMNLDIKKMPLGKLSKQQIAKGFEALEEIEEA-IKNKSRESTLSELSSKFFTIIPHNFGRNRPPVINTDEIIHSKKEMLLVLADIEIAQSL--KAESEKAKEEMVETVPHPIDQDYQSLKCNLSILKKKSKEFKIIEKYLKAT-GHGLTIVDVWQVDREKEAERFKENNALENRKLLWHGTNVAVVAAILKSGLRIMPHSGGRVGQGIYFASENEKSAGYVRLS-NRIGIMFLNEVALGREYTITQDDHTLRKAPAGYDSVVARGRQEPDSANDVTIDLDGKKVTVPQGKAKKQPQYEE--SYFHNSEYLIYKESQCRIRY 518
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Cavefish
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:NCBI gene;Acc:103034813]) HSP 1 Score: 402.134 bits (1032), Expect = 1.862e-132 Identity = 238/438 (54.34%), Postives = 307/438 (70.09%), Query Frame = 2
Query: 242 VVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSD--ASE---KFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGK 1540
V +DYDCMLNQTNI NNNK+YVIQ++ G Y+ WTRWGRVGE+G GP N + A K F+KKF+DKTKN+W +R+NF S GKYTL+E+ D D+ +EV V D A+E P L TQ L+ IF DMF A+ + LD KK+PLGKLSK QI KGFE LEE++ KN + + L ELSSKF+TIIPH+FGR RP I T + + K +MLLVL DIE Q+L + E + ++ + P+P+D+ ++ L +L IL KS+E+KIIE+Y++ T + I++VW+VDR E + F+ + A+ NRKLLWHGTN+AVVAAILKSGLRIMPHSGGRVG+GIYFASEN KSAGYV + +R G+MFLNEVALG+E + DD ++ K PAG++SVVA+G+ EPDS + IDLDG KV VP GK
Sbjct: 61 VHEDYDCMLNQTNIGNNNNKFYVIQVLVDGGTYYCWTRWGRVGESGQNNLAGPTNA-DAAIKNFEKKFKDKTKNNWSDRENFVSHSGKYTLIEV---DGDQDAEVKVDAVDGRAAEVKKNILPCTLDDPTQRLIKFIFNNDMFKEAMENMNLDIKKMPLGKLSKQQIAKGFEALEEIEEA-IKNKSRESTLSELSSKFFTIIPHNFGRNRPPVINTDEIIHSKKEMLLVLADIEIAQSL--KAESEKAKEEMVETVPHPIDQDYQSLKCNLSILKKKSKEFKIIEKYLKATG-HGLTIVDVWQVDREKEAERFKENNALENRKLLWHGTNVAVVAAILKSGLRIMPHSGGRVGQGIYFASENEKSAGYVRLS-NRIGIMFLNEVALGREYTITQDDHTLRKAPAGYDSVVARGRQEPDSANDVTIDLDGKKVTVPQGK 489
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Cavefish
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:NCBI gene;Acc:103034813]) HSP 1 Score: 380.948 bits (977), Expect = 3.092e-126 Identity = 223/417 (53.48%), Postives = 291/417 (69.78%), Query Frame = 2
Query: 242 VVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDA-----SEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEP 1477
V +DYDCMLNQTNI NNNK+YVIQ++ G Y+ WTRWGRVGE+G GP N + A K F+KKF+DKTKN+W +R+NF S GKYTL+E+ D D+ +EV V D + P L TQ L+ IF DMF A+ + LD KK+PLGKLSK QI KGFE LEE++ KN + + L ELSSKF+TIIPH+FGR RP I T + + K +MLLVL DIE Q+L + E + ++ + P+P+D+ ++ L +L IL KS+E+KIIE+Y++ T + I++VW+VDR E + F+ + A+ NRKLLWHGTN+AVVAAILKSGLRIMPHSGGRVG+GIYFASEN KSAGYV + +R G+MFLNEVALG+E + DD ++ K PAG++SVVA+G+ EP
Sbjct: 61 VHEDYDCMLNQTNIGNNNNKFYVIQVLVDGGTYYCWTRWGRVGESGQNNLAGPTNA-DAAIKNFEKKFKDKTKNNWSDRENFVSHSGKYTLIEV---DGDQDAEVKVDAVDGRAAEVKKNILPCTLDDPTQRLIKFIFNNDMFKEAMENMNLDIKKMPLGKLSKQQIAKGFEALEEIEEA-IKNKSRESTLSELSSKFFTIIPHNFGRNRPPVINTDEIIHSKKEMLLVLADIEIAQSL--KAESEKAKEEMVETVPHPIDQDYQSLKCNLSILKKKSKEFKIIEKYLKAT-GHGLTIVDVWQVDREKEAERFKENNALENRKLLWHGTNVAVVAAILKSGLRIMPHSGGRVGQGIYFASENEKSAGYVRLS-NRIGIMFLNEVALGREYTITQDDHTLRKAPAGYDSVVARGRQEP 468
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Cavefish
Match: parp2 (poly(ADP-ribose) polymerase 2 [Source:NCBI gene;Acc:103030103]) HSP 1 Score: 259.996 bits (663), Expect = 7.669e-78 Identity = 175/474 (36.92%), Postives = 255/474 (53.80%), Query Frame = 2
Query: 248 DDYDCMLNQTNIDGNNNKYYVIQMIQ--YNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQ-SRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
D YD MLNQTN+ NNNKYY+IQ++Q + Y VW RWGRVG+ G + +A + F KKF DKTKN W++R NF+ V GKY L+ M D E ++ +K PS+L + Q L++LI + ++K DTKK PLGKL+ QI G+ L+ ++ E K +LLE ++FYT IPHDFG R P TI T + ++EKM +L L+DI+ + K ESSS +PLD ++ L L + S E+++IE+Y+++T + +++++ VDR E +F + NR LLWHG+ ++ IL GLR+ P +G G+GIYFA + KSA Y NQ + G++ L EVALG + + + P+G S G+T PD K + LDG VP+G V + G S E+++Y +Q R+RY
Sbjct: 175 DIYDVMLNQTNLQFNNNKYYLIQLLQDDHAKAYSVWMRWGRVGKVGQNNLVSCGGNLAEAKEIFKKKFLDKTKNEWEDRANFEKVPGKYDLVFMDYTGNDNEEESCDVSTSVQKK--PSQLDLKLQSLLELICDIKAMEECVLEMKFDTKKAPLGKLTVEQIRAGYASLKRIE-ECLKKKGSNRELLEACNQFYTRIPHDFGLRVPPTIRTEEELKEKMALLEALSDIQ-----IAVKMVESSSHSDE----HPLDRQYHSLKCQLQPVTPNSHEFQVIEKYLQSTHAPTHSDYTMTVLDIFLVDREGERDSFLTE--MHNRMLLWHGSRLSNWVGILSQGLRVAPPEAPVTGYMFGKGIYFADMSSKSANYCFTNQKNNIGLLLLCEVALGDCNEMLDANYDADRLPSGKHSTKGLGQTGPDPK--NFVTLDG--ATVPMGPGVKTGVGQGGGCSLLYNEFVVYNPAQTRMRY 630
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Cavefish
Match: parp2 (poly(ADP-ribose) polymerase 2 [Source:NCBI gene;Acc:103030103]) HSP 1 Score: 248.825 bits (634), Expect = 7.903e-74 Identity = 173/485 (35.67%), Postives = 256/485 (52.78%), Query Frame = 2
Query: 221 TLFHGGIVVDDYDCM--LNQTNIDGNNNKYYVIQMIQ--YNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQ-SRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
T+ G D +C L +TN+ NNNKYY+IQ++Q + Y VW RWGRVG+ G + +A + F KKF DKTKN W++R NF+ V GKY L+ M D E ++ +K PS+L + Q L++LI + ++K DTKK PLGKL+ QI G+ L+ ++ E K +LLE ++FYT IPHDFG R P TI T + ++EKM +L L+DI+ + K ESSS +PLD ++ L L + S E+++IE+Y+++T + +++++ VDR E +F + NR LLWHG+ ++ IL GLR+ P +G G+GIYFA + KSA Y NQ + G++ L EVALG + + + P+G S G+T PD K + LDG VP+G V + G S E+++Y +Q R+RY
Sbjct: 147 TVVMKGKAPVDLECKAKLGKTNLQFNNNKYYLIQLLQDDHAKAYSVWMRWGRVGKVGQNNLVSCGGNLAEAKEIFKKKFLDKTKNEWEDRANFEKVPGKYDLVFMDYTGNDNEEESCDVSTSVQKK--PSQLDLKLQSLLELICDIKAMEECVLEMKFDTKKAPLGKLTVEQIRAGYASLKRIE-ECLKKKGSNRELLEACNQFYTRIPHDFGLRVPPTIRTEEELKEKMALLEALSDIQ-----IAVKMVESSSHSDE----HPLDRQYHSLKCQLQPVTPNSHEFQVIEKYLQSTHAPTHSDYTMTVLDIFLVDREGERDSFLTE--MHNRMLLWHGSRLSNWVGILSQGLRVAPPEAPVTGYMFGKGIYFADMSSKSANYCFTNQKNNIGLLLLCEVALGDCNEMLDANYDADRLPSGKHSTKGLGQTGPDPK--NFVTLDG--ATVPMGPGVKTGVGQGGGCSLLYNEFVVYNPAQTRMRY 613
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003213.1 (pep scaffold:Pmarinus_7.0:GL484848:6623:9574:1 gene:ENSPMAG00000002936.1 transcript:ENSPMAT00000003213.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 52.7582 bits (125), Expect = 1.514e-8 Identity = 22/39 (56.41%), Postives = 29/39 (74.36%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYNG--KYFVWTRWGR 364
YD MLNQTN+ NNNK+Y+IQ+++ N + VW RWGR
Sbjct: 100 YDVMLNQTNVGLNNNKFYLIQLLRDNDIKSFSVWMRWGR 138
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009885.1 (pep scaffold:Pmarinus_7.0:GL476547:520883:546470:1 gene:ENSPMAG00000008938.1 transcript:ENSPMAT00000009885.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.5286 bits (127), Expect = 1.192e-7 Identity = 60/237 (25.32%), Postives = 106/237 (44.73%), Query Frame = 2
Query: 638 FQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEI-SKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIE-QYVENTKCR--NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSG-----------GRVGRGIYFA 1303
F + +++ AL L ++P+ + Q+ K +L +L+ + SK+ L LS++FY IIP PL T + ++ K+D+ + + L KK +SS L +F L L L+ S ++ I Q ++++ R KI+ +++VDR +E FR + N + L+H + IL GL ++P + G +G GIYF+
Sbjct: 8 FVSTVWSEALGHLS-QILQVPILLIEPKQVTKAEAILLQLKKAVLSKDVHDEGALERLSNEFYKIIPQKHVAVCPL--TGMASISAKLDL------CQMRKENLALKKLTASSHSATTLA------QFTALRCSLLHLEPNSSDFNSIRNQLLQSSHGRLDGFKILKIFRVDRPAEIGQFR--SEVGNTRSLFHAFAPRSLLGILSRGL-LLPKTVVGEFGVERTDIGMLGCGIYFS 226
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009886.1 (pep scaffold:Pmarinus_7.0:GL476547:520883:541043:1 gene:ENSPMAG00000008938.1 transcript:ENSPMAT00000009886.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.1434 bits (126), Expect = 1.340e-7 Identity = 60/239 (25.10%), Postives = 107/239 (44.77%), Query Frame = 2
Query: 638 FQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEI-SKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIE-QYVENTKCRNVK----IINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSG-----------GRVGRGIYFA 1303
F + +++ AL L ++P+ + Q+ K +L +L+ + SK+ L LS++FY IIP PL T + ++ K+D+ + + L KK +SS L +F L L L+ S ++ I Q ++++ R+V I+ +++VDR +E FR + N + L+H + IL GL ++P + G +G GIYF+
Sbjct: 8 FVSTVWSEALGHLS-QILQVPILLIEPKQVTKAEAILLQLKKAVLSKDVHDEGALERLSNEFYKIIPQKHVAVCPL--TGMASISAKLDL------CQMRKENLALKKLTASSHSATTLA------QFTALRCSLLHLEPNSSDFNSIRNQLLQSSHGRSVAAPSDILKIFRVDRPAEIGQFR--SEVGNTRSLFHAFAPRSLLGILSRGL-LLPKTVVGEFGVERTDIGMLGCGIYFS 228
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Nematostella
Match: EDO46812 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNW1]) HSP 1 Score: 241.121 bits (614), Expect = 3.367e-69 Identity = 165/470 (35.11%), Postives = 251/470 (53.40%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYN--GKYFVWTRWGRVGENGATLKLGPY-NTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRN-----VKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQS-RFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNIT-SSFGQSEYLIYQESQCRIRY 1621
Y L +I N YY +Q+++ + + +++ WGRVG KL N+ A + F++ +++KT N W RDNF ++ LE+ D + E +V E S SKL + Q L+ +IF + L + ++D KK+PLGKL+K QI K + VL E Q +S+ KTA +L++S++FYT+IPHDFG R+P + + ++ K++ML L DIE +LL++ E + +P+D +K L D+++LDHKS E+ +I +YV NT +++++V+K+ R EE F+ K + NR+LLWHG+ A IL GLRI P +G G+G+YFA KSA Y + S G++ L EVALG L H I K P G SV GKT PD + DG +VP GK + SS +EY++Y +Q ++Y
Sbjct: 505 YSATLGMVDISRGTNSYYKLQVLKKDKSSRCYLFRSWGRVGTTIGGSKLEDCGNSHNSAVQSFEELYREKTGNEWSERDNFVKHPNRFYPLEI---DYGQAHEDVVKAK--IEMGSKSKLPSQIQELIKMIFDVESMKKTLIEFEIDLKKMPLGKLTKRQIEKAYSVLGEAQQILSEAASKTA-VLDVSNRFYTLIPHDFGMRKPPLLDNQELIKTKIEMLDNLIDIEVAFSLLQSSDGEDAE--------DPIDINYKKLKTDIEVLDHKSAEFGLISEYVSNTHADTHRQYELELLDVFKIKREGEEALFKPFKQLHNRQLLWHGSRTTNYAGILSQGLRIAPPEAPVTGYMFGKGVYFADMVSKSANYCCTSPSNNIGLLLLCEVALGNMHELKH-ASFIKKVPKGKHSVKGLGKTAPDPSATHTFE-DGT--IVPKGKGCPAPVKDSSLLYNEYIVYDTAQINMKY 956
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Nematostella
Match: EDO46480 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ13]) HSP 1 Score: 219.55 bits (558), Expect = 1.494e-64 Identity = 170/473 (35.94%), Postives = 254/473 (53.70%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYNG--KYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXX-XXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRN-----VKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSR-FGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
+D MLNQTN+ NNNKYY+IQ+++ N KY+ W RWGRVG +G L + DA K+ +K DKTKN W++R +F V+GKY LL M K E E EV + SKL + LV+LI AL ++K DTKK PLG S+ + + + + I + + + SS + T + +RP + T + V+EK+++L L DI+ +LK +K D K +P D+ ++ L DL+ LDH +++K+++ YVENT + +++ +V+ V R ++++F + NR LLWHG+ + A ILK GLRI P +G G+GIYFA + KSA Y +S+ G++ L+EV+LGK L D + K PAG +SV A GK PD N + DG + +P GK + +TS G + EY++Y Q R+RY
Sbjct: 32 WDAMLNQTNVMNNNNKYYLIQLLEDNTAKKYYTWMRWGRVGFDGQK-NLQAFGANLDAAKRTFEKKFSDKTKNDWEDRASFTKVQGKYDLLIMDYKAE-ENDEVDAPVKEEKPAKPESKLDCRVRELVELICNVQAMEEALKEMKYDTKKAPLGSFSEYHVCH-YTIQLRMTGRIVPVSPRCKGSMTCSS-WITRLKRTMKMKRPPLLRTNEEVKEKLELLEALGDIQVAITMLK---------EKVDDKMHPADKHYESLHCDLEPLDHAHDDFKMVKMYVENTHAQTHNQYKMEVEDVFVV--RHQKEDFL---DVGNRMLLWHGSRLTNWAGILKQGLRIAPPEAPVTGYMFGKGIYFADMSSKSANYCFATRSKNTGLVLLSEVSLGKSNVLLTADYNAAKLPAGHQSVKALGKFAPDPTQN-VVRPDG--LTIPCGKGIATGVTSPNGYTLMYNEYIVYDTRQVRMRY 483
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Nematostella
Match: EDO26345 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TC91]) HSP 1 Score: 103.605 bits (257), Expect = 4.870e-25 Identity = 63/153 (41.18%), Postives = 90/153 (58.82%), Query Frame = 2
Query: 455 TKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLV 913
TKN W++R +F V+GKY LL M K E E EV + SKL + LV+LI AL ++K DTKK PLGKL+ QI G+E L+++++ ISK + KL++ +FYT IPH FG +RP + T + V+EK+++L V
Sbjct: 5 TKNDWEDRASFTKVQGKYDLLIMDYKAE-ENDEVDAPVKEEKPAKPESKLDCRVRELVELICNVQAMEEALKEMKYDTKKAPLGKLTTDQIKAGYEALKKIESCISKGDYGN-KLVKACDEFYTRIPHCFGMKRPPLLRTNEEVKEKLELLEV 155 HSP 2 Score: 56.6102 bits (135), Expect = 4.860e-9 Identity = 30/77 (38.96%), Postives = 45/77 (58.44%), Query Frame = 2
Query: 1160 NFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSR-FGVMFLNE 1375
++ I + ++ LLWHG+ + A ILK GLRI P +G G+GIYFA + KSA Y +S+ G++ L+E
Sbjct: 165 SYTIQPLLYSQMLLWHGSRLTNWAGILKQGLRIAPPEAPVTGYMFGKGIYFADMSSKSANYCFATRSKNTGLVLLSE 241
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Nematostella
Match: EDO46659 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPC2]) HSP 1 Score: 77.7962 bits (190), Expect = 6.538e-15 Identity = 78/308 (25.32%), Postives = 132/308 (42.86%), Query Frame = 2
Query: 743 VLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYV--ENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMP-----------HSGGRVGRGIYFASENGKSAGYVACNQ--SRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
++EE N ++N EK +KL E +F ++IPH + L + EK ++ ++ D ++ + + S + L ++K L ++ L + EYK I++ E T ++ ++NV+ + R E+ N+R + +KLL+H + + IL GL ++P G +G GIYFA SA Y + SRF M +N+VALGK K + +PP G+ SV+ TE S F E+++Y Q ++RY
Sbjct: 71 MIEEFDN--TQNKEKISKLWE---EFDSLIPHQIKIKDSTVNKGL--IAEKQNLCQLIRD------MVTISEATNMSTVSSHLA------KYKALRCHIEALHPEEAEYKAIKELAIEEQTGSNDIIVLNVFSLHRPVEDINYR--HGLGRQKLLFHASRVRNFVGILSRGL-LLPTIVVDDFGGQRSDAGMLGHGIYFADRASTSAKYSSPGMLGSRF--MLVNKVALGKSKEYRKFTKDLTRPPDGYNSVIGVKATETQP--------------------------SDFKDDEFVVYDTKQQQMRY 328
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Nematostella
Match: EDO29976 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T240]) HSP 1 Score: 62.7734 bits (151), Expect = 9.090e-11 Identity = 63/227 (27.75%), Postives = 109/227 (48.02%), Query Frame = 2
Query: 254 YDCMLNQTNID----GNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLL--EMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQ--LKLDTKKLPLGKLSKPQIMKGFEVLE-------------ELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLT 865
YD ++ + ++ G NN +Y +Q+I GK + + TRWGR+G+ G +L P++ + A +F K F+ KT N WD + +F KY+L+ E + + ++ D E PSKL K Q L+ I + +++ L++D + +P G+LS I + VLE ++ + + ++ L+ LS Y +I H G RR L+
Sbjct: 89 YDILMTKVDVKYGYFGLNN-FYKMQVIFEKGKNLWVLLTRWGRIGDRGQH-QLTPFSDAKAATDEFKKIFRSKTGNLWDEKGSFVKHPKKYSLVLPERNPQFHHRKPKDILKPFDL-EACPPSKLPKPLQTLMKAITDQEWLRKSVSHHSLQVDPEFMPFGRLSLETINRARGVLEKICKRDGYVISFSKIDDYVISFSKIDGYLISLSKSGYFVISHSVGPRRKLS 312
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Medaka
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:NCBI gene;Acc:101172069]) HSP 1 Score: 439.884 bits (1130), Expect = 1.348e-148 Identity = 253/502 (50.40%), Postives = 330/502 (65.74%), Query Frame = 2
Query: 143 FDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDA-----SEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT--KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVH--RNITSSFGQSEYLIYQESQCRIRY 1621
F S K AL + K +D+ L G V +DY CMLNQTNI NNNK+YVIQ++Q N +++ W RWGRVGE G KL ++T E A K F+KKF+DKTKN W NR NF + GKYTL+E+ + ++ +EV V + D + P L + TQ L+ LIF DMF A+ + LD KK+PLGKLSK QI KGFEVLEE++ ++K N++ L ELSSKF+T IPH+FGR RP TI T + + K ML+VL DIE Q L + E + ++ + P+ LD+ + L L +LD KS+ +KIIE Y++ T K N I+NVW+VDR E + F + + NR+LLWHGTNIAVVAAILKSGLRIMP SGGRVGRGIYFASEN KS YV + ++ GVMFL+EVALG+E + D+ S+ + P+GF+SVVA+G+ EPD + I L+G +V VP GK H R SSF SEYLIY+ESQCR+R+
Sbjct: 26 FTSAKEALLAAGAQPKGRRAVDE-QCPLASTGEVYEDYGCMLNQTNIGHNNNKFYVIQVVQENKRFYSWNRWGRVGEVGQN-KLNSFDTPEKAVKDFEKKFKDKTKNDWSNRSNFVTHPGKYTLIEV---EGEQDAEVKVDSVDGKAVKVPKNTLPCTLDEATQKLITLIFSNDMFKEAMECMDLDIKKMPLGKLSKVQIAKGFEVLEEIEAALNKPNQRHL-LEELSSKFFTTIPHNFGRNRPPTINTKEIIEHKKQMLMVLADIELAQTL--KSETEKAQEEMIETVPHHLDQDYMSLKCKLSLLDKKSKTFKIIETYLKATSDKFYNPTIVNVWEVDREMEGQRFAENDKLENRRLLWHGTNIAVVAAILKSGLRIMPQSGGRVGRGIYFASENSKSICYVRTS-NKTGVMFLSEVALGREYTITKDEPSLKEAPSGFDSVVARGRVEPDPSKDTFITLEGKEVAVPQGKAQHQPRFSNSSFCNSEYLIYKESQCRLRF 518
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Medaka
Match: parp2 (poly(ADP-ribose) polymerase 2 [Source:NCBI gene;Acc:101165670]) HSP 1 Score: 259.996 bits (663), Expect = 5.329e-78 Identity = 182/508 (35.83%), Postives = 268/508 (52.76%), Query Frame = 2
Query: 152 IKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEM--GVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQS-RFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
+KT + KG + A ++ G +V YD MLNQTN+ NNNK+Y+IQ++Q + + VW RWGRVG+ G A F KKF DKT+N W+ R +F V GKY ++ M +++E + V+ DA+ KL + Q L++LI + ++K DT+K PLGKL+ QI G+ L++++ E K + LLE ++FYT IPHDFG R P I T ++EK+ +L L+DI+ + K +SS AD + +PLD + L +L LD S E+K+IE+Y+++T + +++++ VDR E ++F + NR LLWHG+ ++ IL GLR+ P +G G+GIYFA + KSA Y NQS G++ L EVALG L D PAG S G+T PD K + LDG V VP+G V +S G S E+++Y +Q R+RY
Sbjct: 141 VKTVVMKGRAPVDPECNAKLGKAHVYSEGSIV--YDVMLNQTNLQFNNNKFYLIQLLQDDSSKSFSVWMRWGRVGKVGQNSLTACGGDLLKAKDIFKKKFFDKTRNEWEQRGSFVKVAGKYDMVFMDYSTNEKEENTTVV----DAATNKRSCKLDPKVQSLLELICDLKAMEECVLEMKFDTRKAPLGKLTSEQIRAGYAALKKIE-ECLKRKGSSRDLLEACNQFYTRIPHDFGLRPPPVIHTDAELKEKISLLEALSDIQ-----IAVKMVQSS----ADSEEHPLDRHYHSLKCNLQPLDSTSSEFKVIEKYLQSTHAPTHRDYGMTVLDIFSVDRDGESESFL--SDLHNRTLLWHGSRLSNWVGILSKGLRVAPPEAPVTGYMFGKGIYFADMSSKSANYCFANQSNHVGLLLLCEVALGDCNELLDADYEANNLPAGKHSTKGLGQTAPDPK--NSVTLDG--VTVPMGPGVKTGAANSSGYSLLYNEFIVYSPAQTRMRY 626
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Medaka
Match: parp2 (poly(ADP-ribose) polymerase 2 [Source:NCBI gene;Acc:101165670]) HSP 1 Score: 243.817 bits (621), Expect = 6.055e-73 Identity = 169/469 (36.03%), Postives = 248/469 (52.88%), Query Frame = 2
Query: 263 MLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQS-RFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQS----EYLIYQESQCRIRY 1621
+L TN+ NNNK+Y+IQ++Q + + VW RWGRVG+ G A F KKF DKT+N W+ R +F V GKY ++ M + T+E + T + S L + Q L++LI + ++K DT+K PLGKL+ QI G+ L++++ E K + LLE ++FYT IPHDFG R P I T ++EK+ +L L+DI+ + K +SS AD + +PLD + L +L LD S E+K+IE+Y+++T + +++++ VDR E ++F + NR LLWHG+ ++ IL GLR+ P +G G+GIYFA + KSA Y NQS G++ L EVALG L D PAG S G+T PD K + LDG V VP+G V +S G S E+++Y +Q R+RY
Sbjct: 67 LLTSTNLQFNNNKFYLIQLLQDDSSKSFSVWMRWGRVGKVGQNSLTACGGDLLKAKDIFKKKFFDKTRNEWEQRGSFVKVAGKYDMVFM----DYSTNEKVETKTRVLSLKVFSSLDPKVQSLLELICDLKAMEECVLEMKFDTRKAPLGKLTSEQIRAGYAALKKIE-ECLKRKGSSRDLLEACNQFYTRIPHDFGLRPPPVIHTDAELKEKISLLEALSDIQ-----IAVKMVQSS----ADSEEHPLDRHYHSLKCNLQPLDSTSSEFKVIEKYLQSTHAPTHRDYGMTVLDIFSVDRDGESESFL--SDLHNRTLLWHGSRLSNWVGILSKGLRVAPPEAPVTGYMFGKGIYFADMSSKSANYCFANQSNHVGLLLLCEVALGDCNELLDADYEANNLPAGKHSTKGLGQTAPDPK--NSVTLDG--VTVPMGPGVKTGAANSSGYSLLYNEFIVYSPAQTRMRY 515
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Medaka
Match: parp1 (poly(ADP-ribose) polymerase 1 [Source:NCBI gene;Acc:101157338]) HSP 1 Score: 238.424 bits (607), Expect = 1.213e-67 Identity = 158/469 (33.69%), Postives = 252/469 (53.73%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQ--YNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCR-----NVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSR-FGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNI-TSSFGQSEYLIYQESQCRIRY 1621
Y L +I N YY +Q+++ +Y+V+ WGRVG KL ++ K A F +++KT N W + NF K+ LE+ ++E + L ++ + SKL K Q L+ +IF + A+ + ++D +K+PLGKLSK QI + +L E+Q +S + A++L+LS++FYT+IPHDFG ++P + +LD ++ K++ML L DIE +LL+ D + +P+D ++ L ++++D ++E ++I QYV+NT +++ ++K+ R E + FR + + NR+LLWHG+ A I+ GLRI P +G G+G+YFA KSA Y +QS G++ L EVALG L I K P G SV G+T PD + + LDG V VPLGK V NI +S +EY++Y +Q ++Y
Sbjct: 554 YSATLGLVDIVRGTNSYYKLQLLEDDLQKRYWVFRSWGRVGTTIGGNKLDKFHDKNSALDNFLSVYKEKTGNEWGS-SNFIKYPTKFYPLEIDYGQDEEAVKRLTASAG-----TKSKLPKPVQELIKMIFDVESMKKAMVEFEIDLQKMPLGKLSKRQIQSAYALLTEVQQAVS-DCVPEAQILDLSNRFYTLIPHDFGMKKPPLLNSLDYIQAKVEMLDNLLDIEVAYSLLRGG--------AQDNEHDPIDINYEKLKTKIEVVDKSTQEAEVITQYVKNTHAATHNTYTLEVQEIFKIGREGERQRFRPFEELHNRQLLWHGSRATNYAGIMSQGLRIAPPEAPVTGYMFGKGVYFADMVSKSANYCHTSQSDPVGLILLAEVALGNMHEL-KKASHITKLPKGKHSVKGLGRTAPDP--SATVTLDG--VQVPLGKGVQTNIDDTSLLYNEYIVYDVAQINLKY 1002
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Medaka
Match: parp2 (poly(ADP-ribose) polymerase 2 [Source:NCBI gene;Acc:101165670]) HSP 1 Score: 220.705 bits (561), Expect = 3.118e-63 Identity = 164/503 (32.60%), Postives = 242/503 (48.11%), Query Frame = 2
Query: 152 IKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEM--GVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC-----RNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGG------------------------------------------------RVGRGIYFASENGKSAGYVACNQS-RFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSK 1486
+KT + KG + A ++ G +V YD MLNQTN+ NNNK+Y+IQ++Q + + VW RWGRVG+ G A F KKF DKT+N W+ R +F V GKY ++ M +++E + V+ DA+ KL + Q L++LI + ++K DT+K PLGKL+ QI G+ L++++ E K + LLE ++FYT IPHDFG R P I T ++EK+ +L L+DI+ + K +SS AD + +PLD + L +L LD S E+K+IE+Y+++T + +++++ VDR E ++F + NR LLWHG+ ++ IL GLR+ P + G+GIYFA + KSA Y NQS G++ L EVALG L D PAG S G+T PD K
Sbjct: 141 VKTVVMKGRAPVDPECNAKLGKAHVYSEGSIV--YDVMLNQTNLQFNNNKFYLIQLLQDDSSKSFSVWMRWGRVGKVGQNSLTACGGDLLKAKDIFKKKFFDKTRNEWEQRGSFVKVAGKYDMVFMDYSTNEKEENTTVV----DAATNKRSCKLDPKVQSLLELICDLKAMEECVLEMKFDTRKAPLGKLTSEQIRAGYAALKKIE-ECLKRKGSSRDLLEACNQFYTRIPHDFGLRPPPVIHTDAELKEKISLLEALSDIQ-----IAVKMVQSS----ADSEEHPLDRHYHSLKCNLQPLDSTSSEFKVIEKYLQSTHAPTHRDYGMTVLDIFSVDRDGESESFL--SDLHNRTLLWHGSRLSNWVGILSKGLRVAPPEAPVTGYMVCQEEASRCCTFVLFLFPILREFSRFGLNHFDPLKPTILSFSMQFGKGIYFADMSSKSANYCFANQSNHVGLLLLCEVALGDCNELLDADYEANNLPAGKHSTKGLGQTAPDPK 625
BLAST of Poly [ADP-ribose] polymerase vs. Planmine SMEST
Match: SMESG000011115.1 (SMESG000011115.1) HSP 1 Score: 971.459 bits (2510), Expect = 0.000e+0 Identity = 502/516 (97.29%), Postives = 502/516 (97.29%), Query Frame = 2
Query: 74 MPPKRXXXXXXXXXXXXXXXXNEFDSIKTALTKGPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
MPPKRKASAKLKKAPVKKKVKNEFDSIKTALTKGPSFRKK HTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHKQFDKKFQDKTKNHWDNRDNFKS DEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY
Sbjct: 1 MPPKRKASAKLKKAPVKKKVKNEFDSIKTALTKGPSFRKKIHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYNGKYFVWTRWGRVGENGATLKLGPYNTKEDAHKQFDKKFQDKTKNHWDNRDNFKS-------------DEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPHSGGRVGRGIYFASENGKSAGYVACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 503
BLAST of Poly [ADP-ribose] polymerase vs. Planmine SMEST
Match: SMESG000045968.1 (SMESG000045968.1) HSP 1 Score: 232.261 bits (591), Expect = 6.619e-66 Identity = 160/494 (32.39%), Postives = 256/494 (51.82%), Query Frame = 2
Query: 173 GPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYN--GKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC--RNVKII--NVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYV-ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
G + + IDK A L+ D + +L +I +N +Y IQ+++ + K++V+ WGR+G + KL ++ + A K F + +KT N W+NR+ FK K+ L++ + + E + S S L + + L+ IF + A+ + K+D+ K+PLGK+S+ QI + +L+ELQ+ + +N KL ELS++FYT++PH+FG P I +L V++K +M+ L +IE L++ +K + N +D +++ L + LD S+ YK +E Y++NT N KI+ +++ V R E + K + NR +LWHG+ A IL GLRI P +G G+G+YFA KSA Y + + S G++ L EVALGK + D +IV P G S G TEPD N D N V+ P+GK V ++I SS +EY++Y Q + RY
Sbjct: 461 GAAVDPDSGLIDK--AHLYQDRKTRDPLNAILGTADIITGSNSFYKIQLLESDKLSKWWVFRSWGRIGTAIGSNKLELFHDLDSAIKNFCGIYLEKTGNKWENRNEFKKCPYKFVPLDIDYGNRAKVIENITEES--------SNLPQTVEGLIRFIFDVESMKRAMLEFKIDSNKMPLGKVSQKQIDISYTILKELQDLLINSNPTKTKLCELSNRFYTMMPHNFGMMSPPLINSLSMVKDKCEMIESLMEIEVAYKLMEAEKGK-----------NIIDSQYEKLHNCISPLDKSSDVYKRLETYLQNTHAPTHNYKIMIEDIFDVSREGESNRYHSFKRLPNRMMLWHGSRRTNWAGILSQGLRIAPPEAPVTGYMFGKGVYFADVVSKSANYCHSSSTSPDGILLLCEVALGKMTERYQADSNIVLKP-GEHSCKGVGLTEPDPNGN----FDDNGVIYPMGKLVQQDIKSSLLYNEYIVYDIGQIKQRY 928
BLAST of Poly [ADP-ribose] polymerase vs. Planmine SMEST
Match: SMESG000045968.1 (SMESG000045968.1) HSP 1 Score: 232.261 bits (591), Expect = 8.848e-66 Identity = 160/494 (32.39%), Postives = 256/494 (51.82%), Query Frame = 2
Query: 173 GPSFRKKTHTIDKFAATLFHGGIVVDDYDCMLNQTNIDGNNNKYYVIQMIQYN--GKYFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASEKFSPSKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTKC--RNVKII--NVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYV-ACNQSRFGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPDSKYNKEIDLDGNKVVVPLGKPVHRNITSSFGQSEYLIYQESQCRIRY 1621
G + + IDK A L+ D + +L +I +N +Y IQ+++ + K++V+ WGR+G + KL ++ + A K F + +KT N W+NR+ FK K+ L++ + + E + S S L + + L+ IF + A+ + K+D+ K+PLGK+S+ QI + +L+ELQ+ + +N KL ELS++FYT++PH+FG P I +L V++K +M+ L +IE L++ +K + N +D +++ L + LD S+ YK +E Y++NT N KI+ +++ V R E + K + NR +LWHG+ A IL GLRI P +G G+G+YFA KSA Y + + S G++ L EVALGK + D +IV P G S G TEPD N D N V+ P+GK V ++I SS +EY++Y Q + RY
Sbjct: 468 GAAVDPDSGLIDK--AHLYQDRKTRDPLNAILGTADIITGSNSFYKIQLLESDKLSKWWVFRSWGRIGTAIGSNKLELFHDLDSAIKNFCGIYLEKTGNKWENRNEFKKCPYKFVPLDIDYGNRAKVIENITEES--------SNLPQTVEGLIRFIFDVESMKRAMLEFKIDSNKMPLGKVSQKQIDISYTILKELQDLLINSNPTKTKLCELSNRFYTMMPHNFGMMSPPLINSLSMVKDKCEMIESLMEIEVAYKLMEAEKGK-----------NIIDSQYEKLHNCISPLDKSSDVYKRLETYLQNTHAPTHNYKIMIEDIFDVSREGESNRYHSFKRLPNRMMLWHGSRRTNWAGILSQGLRIAPPEAPVTGYMFGKGVYFADVVSKSANYCHSSSTSPDGILLLCEVALGKMTERYQADSNIVLKP-GEHSCKGVGLTEPDPNGN----FDDNGVIYPMGKLVQQDIKSSLLYNEYIVYDIGQIKQRY 935
BLAST of Poly [ADP-ribose] polymerase vs. Planmine SMEST
Match: SMESG000067451.1 (SMESG000067451.1) HSP 1 Score: 214.542 bits (545), Expect = 6.730e-61 Identity = 141/424 (33.25%), Postives = 230/424 (54.25%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASE-KFSP--SKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENTK-----CRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSR-FGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPD 1480
+D MLNQTN+ NNNK+Y+IQ+++ + Y+VW RW RVG+ G YN A + F KKF DKTKN W +R F+ + GKY L+++ + E+L TN AS+ K P SKL ++ Q L+ ++F N A++++K D K+PLG+L++ QI G+ L E++ +S+ + L++ + +YT IPHDFG R P I ++ ++ ++++L L+DI+ L+ + D+ +PLD ++ L ++++ + Y++I Y+ T N++++++++V + E +NF NR LLWHG+ I+ GLRI P +G G+GIYFA + KSA Y+ +S+ G + L EV+LG L ++ K P SV G PD
Sbjct: 264 FDVMLNQTNLQFNNNKFYIIQLLKDEKEPIYYVWMRWARVGKIGQMKLTRFYNNLAAAKECFMKKFYDKTKNDWQDRQKFEKINGKYDLVQIDYCKK----EILETNKIASQVKLEPIESKLEEKLQDLMRIVFDLKEMNDAVSEMKYDNNKVPLGRLTEAQIKAGYLALREIEGLLSEGHSSNKSLVQACNTYYTRIPHDFGMRIPPLIRSISEIKRELELLETLSDIKIALKLI---------NENEDVHVHPLDRHYQNLHCIINLVTIDNPIYQLINDYLLLTHGSTHTTYNLEMLDLFEVRKEQEWQNF---DDKGNRMLLWHGSRTTNYGGIISQGLRIAPAEAPVTGHMFGKGIYFADMSTKSANYIYPTRSKNTGFLLLCEVSLGTCNELIKENSRANKLPPNCHSVKGLGIIAPD 671
BLAST of Poly [ADP-ribose] polymerase vs. Planmine SMEST
Match: SMESG000067451.1 (SMESG000067451.1) HSP 1 Score: 214.542 bits (545), Expect = 1.134e-60 Identity = 141/424 (33.25%), Postives = 230/424 (54.25%), Query Frame = 2
Query: 254 YDCMLNQTNIDGNNNKYYVIQMIQYNGK--YFVWTRWGRVGENGATLKLGPYNTKEDAHXXXXXXXXXXTKNHWDNRDNFKSVKGKYTLLEMGVKDEDETSEVLVTNSDASE-KFSP--SKLAKETQFLVDLIFQTDMFNHALAQLKLDTKKLPLGKLSKPQIMKGFEVLEELQNEISKNNEKTAKLLELSSKFYTIIPHDFGRRRPLTITTLDTVREKMDMLLVLTDIESTQALLKTKKPESSSKQKADLKPNPLDERFKMLDVDLDILDHKSEEYKIIEQYVENT-----KCRNVKIINVWKVDRRSEEKNFRIHKAIANRKLLWHGTNIAVVAAILKSGLRIMPH----SGGRVGRGIYFASENGKSAGYVACNQSR-FGVMFLNEVALGKEKPLFHDDGSIVKPPAGFESVVAQGKTEPD 1480
+D MLNQTN+ NNNK+Y+IQ+++ + Y+VW RW RVG+ G YN A + F KKF DKTKN W +R F+ + GKY L+++ + E+L TN AS+ K P SKL ++ Q L+ ++F N A++++K D K+PLG+L++ QI G+ L E++ +S+ + L++ + +YT IPHDFG R P I ++ ++ ++++L L+DI+ L+ + D+ +PLD ++ L ++++ + Y++I Y+ T N++++++++V + E +NF NR LLWHG+ I+ GLRI P +G G+GIYFA + KSA Y+ +S+ G + L EV+LG L ++ K P SV G PD
Sbjct: 290 FDVMLNQTNLQFNNNKFYIIQLLKDEKEPIYYVWMRWARVGKIGQMKLTRFYNNLAAAKECFMKKFYDKTKNDWQDRQKFEKINGKYDLVQIDYCKK----EILETNKIASQVKLEPIESKLEEKLQDLMRIVFDLKEMNDAVSEMKYDNNKVPLGRLTEAQIKAGYLALREIEGLLSEGHSSNKSLVQACNTYYTRIPHDFGMRIPPLIRSISEIKRELELLETLSDIKIALKLI---------NENEDVHVHPLDRHYQNLHCIINLVTIDNPIYQLINDYLLLTHGSTHTTYNLEMLDLFEVRKEQEWQNF---DDKGNRMLLWHGSRTTNYGGIISQGLRIAPAEAPVTGHMFGKGIYFADMSTKSANYIYPTRSKNTGFLLLCEVSLGTCNELIKENSRANKLPPNCHSVKGLGIIAPD 697 The following BLAST results are available for this feature:
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Poly [ADP-ribose] polymerase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015453 ID=SMED30015453|Name=Poly [ADP-ribose] polymerase|organism=Schmidtea mediterranea sexual|type=transcript|length=1796bpback to top protein sequence of SMED30015453-orf-1 >SMED30015453-orf-1 ID=SMED30015453-orf-1|Name=SMED30015453-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=523bp MPPKRKASAKLKKAPVKKKVKNEFDSIKTALTKGPSFRKKTHTIDKFAATback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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