HTH CENPB-type domain-containing protein

Overview
NameHTH CENPB-type domain-containing protein
Smed IDSMED30015452
Length (bp)2507
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of HTH CENPB-type domain-containing protein (SMED30015452) t-SNE clustered cells

Violin plots show distribution of expression levels for HTH CENPB-type domain-containing protein (SMED30015452) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HTH CENPB-type domain-containing protein (SMED30015452) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HTH CENPB-type domain-containing protein (SMED30015452) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30015452

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30015452SMESG000039309.1 SmedASXL_009927SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Celegans
Match: Y44A6D.3 (pep chromosome:WBcel235:V:20790768:20792411:-1 gene:WBGene00012854.1 transcript:Y44A6D.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y44A6D.3)

HSP 1 Score: 56.6102 bits (135), Expect = 1.260e-8
Identity = 25/39 (64.10%), Postives = 30/39 (76.92%), Query Frame = 2 
Query: 1799 YEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            Y  D KL+ ISHA  HGNRAA REFN++ES +R+WRK E
Sbjct:   21 YSIDEKLAIISHAKNHGNRAAGREFNVAESSIREWRKNE 59
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Celegans
Match: Y44A6D.3 (pep chromosome:WBcel235:V:20790768:20792413:-1 gene:WBGene00012854.1 transcript:Y44A6D.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y44A6D.3)

HSP 1 Score: 56.6102 bits (135), Expect = 1.338e-8
Identity = 25/39 (64.10%), Postives = 30/39 (76.92%), Query Frame = 2 
Query: 1799 YEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            Y  D KL+ ISHA  HGNRAA REFN++ES +R+WRK E
Sbjct:   22 YSIDEKLAIISHAKNHGNRAAGREFNVAESSIREWRKNE 60
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Zebrafish
Match: CR352209.1 (pep chromosome:GRCz11:24:26088143:26089609:1 gene:ENSDARG00000103972.2 transcript:ENSDART00000171129.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR352209.1)

HSP 1 Score: 92.0485 bits (227), Expect = 2.077e-27
Identity = 46/86 (53.49%), Postives = 56/86 (65.12%), Query Frame = 3 
Query: 1869 NSTLVNQWYGSGGS----KNTKLSFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESPLGAYFFEK 2114
            N ++V +W          K TK SFRGNKARWPQLE+++EQW+IEQRT GRSVSTV  RL+ T IA DM I  F+  P   + F K
Sbjct:   36 NESMVRKWRKQENELRQVKKTKQSFRGNKARWPQLEDQLEQWIIEQRTAGRSVSTVTIRLRATKIAQDMGIEHFQGGPSWCFRFMK 121

HSP 2 Score: 51.2174 bits (121), Expect = 2.077e-27
Identity = 23/32 (71.88%), Postives = 27/32 (84.38%), Query Frame = 1 
Query: 2104 FLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRT 2199
            F+KRR+LSIR RT ++ QLP DYKEKL IFRT
Sbjct:  119 FMKRRHLSIRARTTVAQQLPADYKEKLDIFRT 150

HSP 3 Score: 76.6406 bits (187), Expect = 2.985e-14
Identity = 35/47 (74.47%), Postives = 42/47 (89.36%), Query Frame = 2 
Query: 1775 MAPVKRHSYEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            MAP+KRH+YEA FKL AIS+AV +GNRAA ++F I+ESMVRKWRKQE
Sbjct:    1 MAPMKRHAYEAQFKLQAISYAVVNGNRAAAKQFQINESMVRKWRKQE 47
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Zebrafish
Match: BX914205.2 (pep chromosome:GRCz11:4:64121772:64123545:-1 gene:ENSDARG00000099590.2 transcript:ENSDART00000170040.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX914205.2)

HSP 1 Score: 92.0485 bits (227), Expect = 2.369e-27
Identity = 46/86 (53.49%), Postives = 56/86 (65.12%), Query Frame = 3 
Query: 1869 NSTLVNQWYGSGGS----KNTKLSFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESPLGAYFFEK 2114
            N ++V +W          K TK SFRGNKARWPQLE+++EQW+IEQRT GRSVSTV  RL+ T IA DM I  F+  P   + F K
Sbjct:   36 NESMVRKWRKQENELRQVKKTKQSFRGNKARWPQLEDQLEQWIIEQRTAGRSVSTVTIRLRATKIAQDMGIEHFQGGPSWCFRFMK 121

HSP 2 Score: 51.2174 bits (121), Expect = 2.369e-27
Identity = 23/32 (71.88%), Postives = 27/32 (84.38%), Query Frame = 1 
Query: 2104 FLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRT 2199
            F+KRR+LSIR RT ++ QLP DYKEKL IFRT
Sbjct:  119 FMKRRHLSIRARTTVAQQLPADYKEKLDIFRT 150

HSP 3 Score: 76.6406 bits (187), Expect = 2.912e-14
Identity = 35/47 (74.47%), Postives = 42/47 (89.36%), Query Frame = 2 
Query: 1775 MAPVKRHSYEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            MAP+KRH+YEA FKL AIS+AV +GNRAA ++F I+ESMVRKWRKQE
Sbjct:    1 MAPMKRHAYEAQFKLQAISYAVVNGNRAAAKQFQINESMVRKWRKQE 47
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Zebrafish
Match: CR354398.1 (pep chromosome:GRCz11:7:64150332:64152087:-1 gene:ENSDARG00000101994.2 transcript:ENSDART00000165234.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR354398.1)

HSP 1 Score: 91.6633 bits (226), Expect = 2.466e-27
Identity = 46/86 (53.49%), Postives = 56/86 (65.12%), Query Frame = 3 
Query: 1869 NSTLVNQWYGSGGS----KNTKLSFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESPLGAYFFEK 2114
            N ++V +W          K TK SFRGNKARWPQLE+++EQW+IEQRT GRSVSTV  RL+ T IA DM I  F+  P   + F K
Sbjct:   36 NESMVRKWRKQENELRQVKKTKQSFRGNKARWPQLEDQLEQWIIEQRTAGRSVSTVTIRLRATKIAQDMGIEHFQGGPSWCFRFMK 121

HSP 2 Score: 51.6026 bits (122), Expect = 2.466e-27
Identity = 23/32 (71.88%), Postives = 27/32 (84.38%), Query Frame = 1 
Query: 2104 FLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRT 2199
            F+KRR+LSIR RT ++ QLP DYKEKL IFRT
Sbjct:  119 FMKRRHLSIRARTTVAQQLPADYKEKLDIFRT 150

HSP 3 Score: 76.6406 bits (187), Expect = 3.788e-14
Identity = 35/47 (74.47%), Postives = 42/47 (89.36%), Query Frame = 2 
Query: 1775 MAPVKRHSYEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            MAP+KRH+YEA FKL AIS+AV +GNRAA ++F I+ESMVRKWRKQE
Sbjct:    1 MAPMKRHAYEAQFKLQAISYAVVNGNRAAAKQFQINESMVRKWRKQE 47
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A3P8QW97 (HTH CENPB-type domain-containing protein OS=Astatotilapia calliptera OX=8154 PE=4 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 6.606e-36
Identity = 37/68 (54.41%), Postives = 49/68 (72.06%), Query Frame = 3 
Query: 1911 KNTKLSFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESPLGAYFFEK 2114
            K T+LSFRG+KARWP+LE ++E+W+IEQR  GRSVSTV  RLK   +A +M+I  F+  P   + F K
Sbjct:   66 KKTQLSFRGHKARWPELEERLERWIIEQRASGRSVSTVTIRLKAVSLAEEMNIEHFQGGPSWCFRFMK 133

HSP 2 Score: 70.8626 bits (172), Expect = 6.606e-36
Identity = 37/55 (67.27%), Postives = 42/55 (76.36%), Query Frame = 2 
Query: 1751 ISIHAAPKMAPVKRHSYEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            I +    KMA  KRH+YEA FKL AIS+A +HGNRAA REF I+ESMVRKWRK E
Sbjct:    7 IVVLTTLKMA--KRHAYEAQFKLKAISYAEEHGNRAAAREFKINESMVRKWRKLE 59

HSP 3 Score: 50.447 bits (119), Expect = 6.606e-36
Identity = 23/32 (71.88%), Postives = 27/32 (84.38%), Query Frame = 1 
Query: 2104 FLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRT 2199
            F+KR + SIRTRT I+ QLP DYKEKLAIFR+
Sbjct:  131 FMKRCHFSIRTRTTIAQQLPADYKEKLAIFRS 162
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A3P9C0G3 (HTH CENPB-type domain-containing protein OS=Maylandia zebra OX=106582 PE=4 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 7.976e-36
Identity = 37/68 (54.41%), Postives = 49/68 (72.06%), Query Frame = 3 
Query: 1911 KNTKLSFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESPLGAYFFEK 2114
            K T+LSFRG+KARWP+LE ++E+W+IEQR  GRSVSTV  RLK   +A +M+I  F+  P   + F K
Sbjct:   66 KKTQLSFRGHKARWPELEERLERWIIEQRASGRSVSTVTIRLKAVSLAEEMNIEHFQGGPSWCFRFMK 133

HSP 2 Score: 70.8626 bits (172), Expect = 7.976e-36
Identity = 37/55 (67.27%), Postives = 42/55 (76.36%), Query Frame = 2 
Query: 1751 ISIHAAPKMAPVKRHSYEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            I +    KMA  KRH+YEA FKL AIS+A +HGNRAA REF I+ESMVRKWRK E
Sbjct:    7 IVVLTTLKMA--KRHAYEAQFKLKAISYAEEHGNRAAAREFKINESMVRKWRKLE 59

HSP 3 Score: 50.447 bits (119), Expect = 7.976e-36
Identity = 23/32 (71.88%), Postives = 27/32 (84.38%), Query Frame = 1 
Query: 2104 FLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRT 2199
            F+KR + SIRTRT I+ QLP DYKEKLAIFR+
Sbjct:  131 FMKRCHFSIRTRTTIAQQLPADYKEKLAIFRS 162
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A3P8N666 (HTH CENPB-type domain-containing protein OS=Astatotilapia calliptera OX=8154 PE=4 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 7.976e-36
Identity = 35/60 (58.33%), Postives = 46/60 (76.67%), Query Frame = 3 
Query: 1911 KNTKLSFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESP 2090
            K T+LSFRG+KARWP+LE ++E+W+IEQR  GRSVSTV  RLK   +A +M+I  F+  P
Sbjct:   66 KKTQLSFRGHKARWPELEERLERWIIEQRASGRSVSTVTIRLKAVSLAEEMNIEHFQGGP 125

HSP 2 Score: 70.8626 bits (172), Expect = 7.976e-36
Identity = 37/55 (67.27%), Postives = 42/55 (76.36%), Query Frame = 2 
Query: 1751 ISIHAAPKMAPVKRHSYEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            I +    KMA  KRH+YEA FKL AIS+A +HGNRAA REF I+ESMVRKWRK E
Sbjct:    7 IVVLTTLKMA--KRHAYEAQFKLKAISYAEEHGNRAAAREFKINESMVRKWRKLE 59

HSP 3 Score: 51.6026 bits (122), Expect = 7.976e-36
Identity = 24/35 (68.57%), Postives = 28/35 (80.00%), Query Frame = 1 
Query: 2095 VLTFLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRT 2199
             L F+KR + SIRTRT I+ QLP DYKEKLAIFR+
Sbjct:  128 CLRFMKRCHFSIRTRTTIAQQLPADYKEKLAIFRS 162
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A3P8RKB0 (HTH CENPB-type domain-containing protein OS=Astatotilapia calliptera OX=8154 PE=4 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 1.172e-35
Identity = 37/68 (54.41%), Postives = 49/68 (72.06%), Query Frame = 3 
Query: 1911 KNTKLSFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESPLGAYFFEK 2114
            K T+LSFRG+KARWP+LE ++E+W+IEQR  GRSVSTV  RLK   +A +M+I  F+  P   + F K
Sbjct:   66 KKTQLSFRGHKARWPELEERLERWIIEQRASGRSVSTVTIRLKAVSLAEEMNIEHFQGGPSWCFRFMK 133

HSP 2 Score: 70.8626 bits (172), Expect = 1.172e-35
Identity = 37/55 (67.27%), Postives = 42/55 (76.36%), Query Frame = 2 
Query: 1751 ISIHAAPKMAPVKRHSYEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            I +    KMA  KRH+YEA FKL AIS+A +HGNRAA REF I+ESMVRKWRK E
Sbjct:    7 IVVLTTLKMA--KRHAYEAQFKLKAISYAEEHGNRAAAREFKINESMVRKWRKLE 59

HSP 3 Score: 49.6766 bits (117), Expect = 1.172e-35
Identity = 22/32 (68.75%), Postives = 27/32 (84.38%), Query Frame = 1 
Query: 2104 FLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRT 2199
            F+KR + SIRTRT ++ QLP DYKEKLAIFR+
Sbjct:  131 FMKRCHFSIRTRTTVAQQLPADYKEKLAIFRS 162
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Match: A0A3P9BX81 (HTH CENPB-type domain-containing protein OS=Maylandia zebra OX=106582 PE=3 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 1.241e-35
Identity = 37/68 (54.41%), Postives = 49/68 (72.06%), Query Frame = 3 
Query: 1911 KNTKLSFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESPLGAYFFEK 2114
            K T+LSFRG+KARWP+LE ++E+W+IEQR  GRSVSTV  RLK   +A +M+I  F+  P   + F K
Sbjct:  230 KKTQLSFRGHKARWPELEERLERWIIEQRASGRSVSTVTIRLKAVSLAEEMNIEHFQGGPSWCFRFMK 297

HSP 2 Score: 70.4774 bits (171), Expect = 1.241e-35
Identity = 37/62 (59.68%), Postives = 43/62 (69.35%), Query Frame = 2 
Query: 1730 CVKFKH*ISIHAAPKMAPVKRHSYEADFKLSAISHAVQHGNRAADREFNISESMVRKWRKQE 1915
            C+     I +    KMA  KRH+YEA FKL AIS+A +HGNRA  REF I+ESMVRKWRK E
Sbjct:  164 CMCIMQDIVVLTTLKMA--KRHAYEAQFKLKAISYAEEHGNRAVAREFKINESMVRKWRKLE 223

HSP 3 Score: 50.447 bits (119), Expect = 1.241e-35
Identity = 23/32 (71.88%), Postives = 27/32 (84.38%), Query Frame = 1 
Query: 2104 FLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRT 2199
            F+KR + SIRTRT I+ QLP DYKEKLAIFR+
Sbjct:  295 FMKRCHFSIRTRTTIAQQLPADYKEKLAIFRS 326
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000039309.1 (SMESG000039309.1)

HSP 1 Score: 370.933 bits (951), Expect = 1.656e-119
Identity = 189/193 (97.93%), Postives = 190/193 (98.45%), Query Frame = 1 
Query:  403 YFKTLHLMNKFHFPVPFTPEITFPGXXXXXXXTDVSTNRRMKRNRDKGIGTAEMEISSGNESEISDEEHFPQIKRQKLSFPKIPSNPLTNNYEFKTQPTKCIPLVDAFERKEEKSGSHIEFRPIASLPDTSINSNGNLSDSTVENGFGTIPKPETESVELYPKENITETSQISHLINESINLMFDDFKLRKGK 981
            Y +TLHLMNKFHFPVPFTPEITFPGNVVVVNNTDVSTNRRMKRNRDKGIGTAEMEISSGNESEISDEEHFPQIKRQKLSFPKIPSNPLTNNYEFKTQPTKCIPLVDAFERKEEKSGSHIEFRPIASLPDTSINSNGNLSDS VENGFGTIPKPETESVELYPKENITETSQISHLINESINLMFDDFKLRK K
Sbjct:  161 YTQTLHLMNKFHFPVPFTPEITFPGNVVVVNNTDVSTNRRMKRNRDKGIGTAEMEISSGNESEISDEEHFPQIKRQKLSFPKIPSNPLTNNYEFKTQPTKCIPLVDAFERKEEKSGSHIEFRPIASLPDTSINSNGNLSDSAVENGFGTIPKPETESVELYPKENITETSQISHLINESINLMFDDFKLRKEK 353
[Close]
BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Match: SMESG000052069.1 (SMESG000052069.1)

HSP 1 Score: 47.7506 bits (112), Expect = 4.405e-9
Identity = 23/54 (42.59%), Postives = 31/54 (57.41%), Query Frame = 3 
Query: 1926 SFRGNKARWPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRES 2087
            S RG  AR+P+LE K+ +W++ QR     VS    RL+  VIA +M I  F  S
Sbjct:    7 SLRGGNARYPELETKLHEWILIQRERELQVSVFRIRLQAQVIAKEMKIEGFAAS 60

HSP 2 Score: 33.113 bits (74), Expect = 4.405e-9
Identity = 17/48 (35.42%), Postives = 27/48 (56.25%), Query Frame = 1 
Query: 2065 ISTIFVKALLVLTFLKRRNLSIRTRTAIS*QLPKDYKEKLAIFRTVLV 2208
            I      + L   F+KR+N+ +R RT    QLPKD++ ++A FR  + 
Sbjct:   54 IEGFAASSQLTDNFMKRKNICVR-RTITKQQLPKDWEFQMAKFRNTIA 100
The following BLAST results are available for this feature:
BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Y44A6D.31.260e-864.10pep chromosome:WBcel235:V:20790768:20792411:-1 gen... [more]
Y44A6D.31.338e-864.10pep chromosome:WBcel235:V:20790768:20792413:-1 gen... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CR352209.12.077e-2753.49pep chromosome:GRCz11:24:26088143:26089609:1 gene:... [more]
BX914205.22.369e-2753.49pep chromosome:GRCz11:4:64121772:64123545:-1 gene:... [more]
CR354398.12.466e-2753.49pep chromosome:GRCz11:7:64150332:64152087:-1 gene:... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3P8QW976.606e-3654.41HTH CENPB-type domain-containing protein OS=Astato... [more]
A0A3P9C0G37.976e-3654.41HTH CENPB-type domain-containing protein OS=Maylan... [more]
A0A3P8N6667.976e-3658.33HTH CENPB-type domain-containing protein OS=Astato... [more]
A0A3P8RKB01.172e-3554.41HTH CENPB-type domain-containing protein OS=Astato... [more]
A0A3P9BX811.241e-3554.41HTH CENPB-type domain-containing protein OS=Maylan... [more]
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of HTH CENPB-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000039309.11.656e-11997.93SMESG000039309.1[more]
SMESG000052069.14.405e-942.59SMESG000052069.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015452 ID=SMED30015452|Name=HTH CENPB-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2507bp
CCGAAATTAATTTCGGTTTCCATCGCTGAATAAATTTATTAATAATAACA
AATAAATGTATTTATAATCTTGAATAAGACTTCATGGTAATAAAGCTACA
CTTATGTTATTAAAATCATCTTTCGTATCAGATTTAAATAAATTTCAACT
TGACTGTCAGACGGATCACTCAGTACCTTTCAGTATGACAATATAGCTAT
ATTACCGTATATAGCCTTATATGACACGTTATACACGCCCATAAAATATC
AAATCGGACAAAATTAGAGTTATAGTTTATAACAACAGCCGAACATTTAA
TATTTCATCAATATTCTTTTACCTCATTATATTCTGATTTTCATTTGTCT
ACCTTTGCTCTATTTTTACTAAAAGAATCAAATTTTACAAATCTACATTT
GATATTTTAAGACTCTCCATCTGATGAATAAGTTCCATTTTCCGGTGCCA
TTTACGCCTGAAATAACCTTTCCCGGTAACGTGGTTGTTGTCAATAATAC
CGATGTATCAACCAATAGGCGTATGAAACGTAACCGAGACAAAGGGATTG
GAACTGCAGAAATGGAAATTTCTAGTGGAAATGAGAGTGAGATATCAGAT
GAAGAGCATTTTCCCCAAATTAAGCGACAGAAGCTTTCTTTTCCGAAAAT
TCCATCTAATCCATTGACTAATAATTATGAGTTTAAAACTCAACCGACTA
AGTGCATTCCATTAGTTGATGCATTCGAAAGGAAAGAGGAAAAATCCGGC
TCACACATTGAATTTCGTCCTATAGCCTCATTGCCAGACACGAGTATAAA
TAGTAATGGAAATCTATCGGATTCCACTGTTGAAAATGGGTTCGGTACAA
TTCCTAAACCTGAAACAGAATCTGTAGAATTATACCCCAAAGAAAATATC
ACCGAAACAAGTCAAATTAGTCATTTAATTAATGAAAGCATTAATTTGAT
GTTTGATGATTTCAAATTAAGAAAAGGTAAAAATGGAATATTATTATATT
ATAAGAATGCATCCATTAAGGACATCTCTAGAACATTAAAATTTTATCTC
CTCCCTGTCTCATTATGTTTCTTCTGTATTATTAATTGTGTCCCCTTTGG
TATGATTCCCTCTCCCCATTCTCCGAATCGTCCTTAATGGGTGCTCCCTA
ATTGAAAATTTTATTTATTATTCATTATTATTAATTTATTATTAGTATTA
TTTAAACTTTTAAAATATTTATTTATCGATATCGGAATCATTTAAATTAA
CATAATTTATATAAATAATAATGTCAGCCAGTTTCCTCAGTGATTATTAT
TATTAAAATGTTTATAAAATGACATATAACATATTTCTACTTAAATTAGA
TAGTGATCACTCCAAAACAAAATTTAACAAGTTTTTGGCCTTCTGCTTCT
TCTTTGCTTGACGAGTTCAAAAAATACTTACACAACATTGAGAAAATAGC
ACATTGATATTTACTGGGCATTTTGATTGTAAATTATTTTCAATAATTTG
TCTACCGTATTTTTCGGACCACTTAAAAGGCACTTAAAATCCTTTCATTT
TCTATAAAATCTTCAGTGCGCCTTATAATGTAGGATTGTGCTTTCTGGCT
TTCTGACCTAGAACCGATTTTATTTGGTACACGACGCTCAAAAATCTGTC
AACATGTTTTAGCATGGCCTTAGTAAGCTTCAAAGCTGCACTGATTGGAT
TGAGCATTACAACCATCGTAGTCAGCAGGTGTGTAAAATTCAAACATTAA
ATTTCTATACACGCTGCCCCAAAAATGGCTCCTGTTAAGAGACATAGTTA
TGAAGCGGATTTCAAACTCAGCGCTATCAGTCACGCAGTACAACATGGAA
ATAGAGCAGCTGATAGAGAATTCAACATTAGTGAATCAATGGTACGGAAG
TGGAGGAAGCAAGAATACCAAACTGAGTTTCCGAGGGAACAAAGCGAGAT
GGCCACAGTTGGAGAACAAAATTGAACAGTGGGTTATTGAACAGAGAACC
GTAGGTAGAAGCGTCTCTACGGTCTTTTTTCGGCTCAAAACAACAGTGAT
AGCACACGACATGGATATCAACGATTTTCGTGAAAGCCCTCTTGGTGCTT
ACTTTTTTGAAAAGGCGTAATCTCTCCATCCGCACAAGAACTGCTATCTC
ATAGCAACTGCCAAAGGATTATAAAGAAAAGCTAGCCATTTTCCGCACGG
TTTTAGTAATTCGACAAAAGTCTTTAACATGGACAAACGTGAACGTATTT
TCATTATATATTGAAGTGGAACTTTCCACTGTCTCGTTATTGCAGTCACA
TAAAAGAAATTTCATTTCTGTCACGTGTAGTTTTTGAAATATTTTTTCAA
AAGCGTATCTGCTTCAGAATATGATTCAATCGATTGAATAGAATTACCTT
CATATGATTATGTAAAGCAATGCTCCGCAACTTTTTTTCACCTACGGCAC
ACTAAATCCTTTCTAGAAATCTCTGGCAAACGACAATGGAAAATATAGAT
CGGAAGA
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protein sequence of SMED30015452-orf-1

>SMED30015452-orf-1 ID=SMED30015452-orf-1|Name=SMED30015452-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=107bp
MKRISNSALSVTQYNMEIEQLIENSTLVNQWYGSGGSKNTKLSFRGNKAR
WPQLENKIEQWVIEQRTVGRSVSTVFFRLKTTVIAHDMDINDFRESPLGA
YFFEKA*
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protein sequence of SMED30015452-orf-2

>SMED30015452-orf-2 ID=SMED30015452-orf-2|Name=SMED30015452-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=238bp
MNKFHFPVPFTPEITFPGNVVVVNNTDVSTNRRMKRNRDKGIGTAEMEIS
SGNESEISDEEHFPQIKRQKLSFPKIPSNPLTNNYEFKTQPTKCIPLVDA
FERKEEKSGSHIEFRPIASLPDTSINSNGNLSDSTVENGFGTIPKPETES
VELYPKENITETSQISHLINESINLMFDDFKLRKGKNGILLYYKNASIKD
ISRTLKFYLLPVSLCFFCIINCVPFGMIPSPHSPNRP*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR018586Brinker_DNA-bd
IPR009057Homeobox-like_sf
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003676nucleic acid binding