cAMP-responsive element modulator

Overview
NamecAMP-responsive element modulator
Smed IDSMED30015409
Length (bp)1844
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of cAMP-responsive element modulator (SMED30015409) t-SNE clustered cells

Violin plots show distribution of expression levels for cAMP-responsive element modulator (SMED30015409) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of cAMP-responsive element modulator (SMED30015409) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for cAMP-responsive element modulator (SMED30015409) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30015409

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30015409h1SMcG0006635 Contig4585GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30015409h1SMcG0006635 Contig4585GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30015409h1SMcG0006635 Contig4585GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
pharynxSMED30015409h1SMcG0021023 Contig4585GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30015409h1SMcG0021023 Contig4585GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30015409h1SMcG0021023 Contig4585GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30015409h1SMcG0006635 dd_Smed_v4_4685_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30015409h1SMcG0006635 dd_Smed_v4_4685_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Human
Match: CREB1 (cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345])

HSP 1 Score: 64.3142 bits (155), Expect = 2.021e-10
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  256 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 326
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Human
Match: CREB1 (cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345])

HSP 1 Score: 64.3142 bits (155), Expect = 2.021e-10
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  256 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 326
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Human
Match: CREB1 (cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345])

HSP 1 Score: 63.929 bits (154), Expect = 2.501e-10
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  270 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 340
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Human
Match: ATF1 (activating transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:783])

HSP 1 Score: 60.4622 bits (145), Expect = 2.324e-9
Identity = 42/56 (75.00%), Postives = 50/56 (89.29%), Query Frame = 1 
Query: 1015 RKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            ++EIRL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+YS KS
Sbjct:  215 KREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSNKS 270
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Human
Match: CREM (cAMP responsive element modulator [Source:HGNC Symbol;Acc:HGNC:2352])

HSP 1 Score: 60.077 bits (144), Expect = 2.662e-9
Identity = 41/60 (68.33%), Postives = 51/60 (85.00%), Query Frame = 1 
Query: 1000 EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKK 1179
            EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  K
Sbjct:  208 EEATRKRELRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHK 267
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Celegans
Match: crh-1 (CREB Homolog; Cyclic AMP-response element binding protein 1 beta [Source:UniProtKB/TrEMBL;Acc:G5ECG1])

HSP 1 Score: 56.9954 bits (136), Expect = 4.132e-9
Identity = 39/66 (59.09%), Postives = 54/66 (81.82%), Query Frame = 1 
Query:  988 LMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            L   +E  +++++RLLKNREAA+ECRRKKKEYVKCLENRV+ LE QNK L++E+  +K++Y +K K
Sbjct:  121 LHGEDESNRKRQVRLLKNREAAKECRRKKKEYVKCLENRVSVLENQNKALIEELKTLKELYCRKEK 186
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Celegans
Match: crh-1 (CREB Homolog; Cyclic AMP-response element binding protein 1 beta [Source:UniProtKB/TrEMBL;Acc:G5ECG1])

HSP 1 Score: 58.151 bits (139), Expect = 6.821e-9
Identity = 39/66 (59.09%), Postives = 54/66 (81.82%), Query Frame = 1 
Query:  988 LMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            L   +E  +++++RLLKNREAA+ECRRKKKEYVKCLENRV+ LE QNK L++E+  +K++Y +K K
Sbjct:  246 LHGEDESNRKRQVRLLKNREAAKECRRKKKEYVKCLENRVSVLENQNKALIEELKTLKELYCRKEK 311
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Celegans
Match: crh-1 (CREB Homolog; Cyclic AMP-response element binding protein 1 beta [Source:UniProtKB/TrEMBL;Acc:G5ECG1])

HSP 1 Score: 57.7658 bits (138), Expect = 8.187e-9
Identity = 39/66 (59.09%), Postives = 54/66 (81.82%), Query Frame = 1 
Query:  988 LMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            L   +E  +++++RLLKNREAA+ECRRKKKEYVKCLENRV+ LE QNK L++E+  +K++Y +K K
Sbjct:  263 LHGEDESNRKRQVRLLKNREAAKECRRKKKEYVKCLENRVSVLENQNKALIEELKTLKELYCRKEK 328
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Celegans
Match: crh-1 (CREB Homolog; Cyclic AMP-response element binding protein 1 beta [Source:UniProtKB/TrEMBL;Acc:G5ECG1])

HSP 1 Score: 57.7658 bits (138), Expect = 9.406e-9
Identity = 39/66 (59.09%), Postives = 54/66 (81.82%), Query Frame = 1 
Query:  988 LMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            L   +E  +++++RLLKNREAA+ECRRKKKEYVKCLENRV+ LE QNK L++E+  +K++Y +K K
Sbjct:  259 LHGEDESNRKRQVRLLKNREAAKECRRKKKEYVKCLENRVSVLENQNKALIEELKTLKELYCRKEK 324
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Celegans
Match: crh-1 (CREB Homolog; Cyclic AMP-response element binding protein 1 beta [Source:UniProtKB/TrEMBL;Acc:G5ECG1])

HSP 1 Score: 57.7658 bits (138), Expect = 9.552e-9
Identity = 39/66 (59.09%), Postives = 54/66 (81.82%), Query Frame = 1 
Query:  988 LMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            L   +E  +++++RLLKNREAA+ECRRKKKEYVKCLENRV+ LE QNK L++E+  +K++Y +K K
Sbjct:  257 LHGEDESNRKRQVRLLKNREAAKECRRKKKEYVKCLENRVSVLENQNKALIEELKTLKELYCRKEK 322
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Fly
Match: CrebB (gene:FBgn0265784 transcript:FBtr0346093)

HSP 1 Score: 53.9138 bits (128), Expect = 1.383e-7
Identity = 42/75 (56.00%), Postives = 56/75 (74.67%), Query Frame = 1 
Query:  964 LTHKSKPGLMNN----EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSK 1176
             T  S P + +N    E+  +++EIRL KNREAARECRRKKKEY+KCLENRVA LE QNK L++E+  +K++Y +
Sbjct:  203 FTEISGPDMSDNSGIAEDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSLKELYCQ 277
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Fly
Match: CrebB (gene:FBgn0265784 transcript:FBtr0310341)

HSP 1 Score: 53.9138 bits (128), Expect = 1.383e-7
Identity = 42/75 (56.00%), Postives = 56/75 (74.67%), Query Frame = 1 
Query:  964 LTHKSKPGLMNN----EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSK 1176
             T  S P + +N    E+  +++EIRL KNREAARECRRKKKEY+KCLENRVA LE QNK L++E+  +K++Y +
Sbjct:  203 FTEISGPDMSDNSGIAEDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSLKELYCQ 277
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Fly
Match: CrebB (gene:FBgn0265784 transcript:FBtr0112879)

HSP 1 Score: 53.9138 bits (128), Expect = 1.383e-7
Identity = 42/75 (56.00%), Postives = 56/75 (74.67%), Query Frame = 1 
Query:  964 LTHKSKPGLMNN----EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSK 1176
             T  S P + +N    E+  +++EIRL KNREAARECRRKKKEY+KCLENRVA LE QNK L++E+  +K++Y +
Sbjct:  203 FTEISGPDMSDNSGIAEDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSLKELYCQ 277
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Fly
Match: CrebB (gene:FBgn0265784 transcript:FBtr0074557)

HSP 1 Score: 53.9138 bits (128), Expect = 1.615e-7
Identity = 42/75 (56.00%), Postives = 56/75 (74.67%), Query Frame = 1 
Query:  964 LTHKSKPGLMNN----EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSK 1176
             T  S P + +N    E+  +++EIRL KNREAARECRRKKKEY+KCLENRVA LE QNK L++E+  +K++Y +
Sbjct:  207 FTEISGPDMSDNSGIAEDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSLKELYCQ 281
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Fly
Match: CrebB (gene:FBgn0265784 transcript:FBtr0310340)

HSP 1 Score: 53.5286 bits (127), Expect = 2.403e-7
Identity = 38/59 (64.41%), Postives = 50/59 (84.75%), Query Frame = 1 
Query: 1000 EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSK 1176
            E+  +++EIRL KNREAARECRRKKKEY+KCLENRVA LE QNK L++E+  +K++Y +
Sbjct:  265 EDQTRKREIRLQKNREAARECRRKKKEYIKCLENRVAVLENQNKALIEELKSLKELYCQ 323
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Zebrafish
Match: crema (cAMP responsive element modulator a [Source:ZFIN;Acc:ZDB-GENE-030131-7031])

HSP 1 Score: 66.2402 bits (160), Expect = 2.162e-11
Identity = 47/75 (62.67%), Postives = 57/75 (76.00%), Query Frame = 1 
Query:  976 SKPGLM-----NNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            S PG M     N EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K +
Sbjct:  226 SSPGAMHSPQPNAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHKPE 300
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Zebrafish
Match: crema (cAMP responsive element modulator a [Source:ZFIN;Acc:ZDB-GENE-030131-7031])

HSP 1 Score: 59.3066 bits (142), Expect = 1.758e-10
Identity = 47/73 (64.38%), Postives = 56/73 (76.71%), Query Frame = 1 
Query:  976 SKPGLM-----NNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKK 1179
            S PG M     N EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K
Sbjct:   36 SSPGAMHSPQPNAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHK 108
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Zebrafish
Match: creb1b (cAMP responsive element binding protein 1b [Source:ZFIN;Acc:ZDB-GENE-050417-355])

HSP 1 Score: 63.5438 bits (153), Expect = 1.994e-10
Identity = 43/68 (63.24%), Postives = 54/68 (79.41%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            P     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  257 PSQGGAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 324
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Zebrafish
Match: creb1a (cAMP responsive element binding protein 1a [Source:ZFIN;Acc:ZDB-GENE-040426-750])

HSP 1 Score: 63.1586 bits (152), Expect = 2.547e-10
Identity = 45/72 (62.50%), Postives = 56/72 (77.78%), Query Frame = 1 
Query:  976 SKPGL--MNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  247 SSPALPSQGAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 318
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Zebrafish
Match: creb1a (cAMP responsive element binding protein 1a [Source:ZFIN;Acc:ZDB-GENE-040426-750])

HSP 1 Score: 63.1586 bits (152), Expect = 2.547e-10
Identity = 45/72 (62.50%), Postives = 56/72 (77.78%), Query Frame = 1 
Query:  976 SKPGL--MNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  247 SSPALPSQGAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 318
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Xenopus
Match: ubl4a (ubiquitin like 4A [Source:Xenbase;Acc:XB-GENE-6455973])

HSP 1 Score: 59.6918 bits (143), Expect = 1.595e-10
Identity = 43/67 (64.18%), Postives = 55/67 (82.09%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            P +M  EE  +++E+RLLKNREAARECR+KKKEYVKCLENRVA LE QNK L++E+  +KD+Y  K+
Sbjct:   40 PQIMA-EEVTRKRELRLLKNREAARECRKKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKT 105
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Xenopus
Match: det1 (DET1, COP1 ubiquitin ligase partner [Source:Xenbase;Acc:XB-GENE-960176])

HSP 1 Score: 63.929 bits (154), Expect = 2.023e-10
Identity = 42/61 (68.85%), Postives = 52/61 (85.25%), Query Frame = 1 
Query: 1000 EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  266 EEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 326
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Xenopus
Match: det1 (DET1, COP1 ubiquitin ligase partner [Source:Xenbase;Acc:XB-GENE-960176])

HSP 1 Score: 63.929 bits (154), Expect = 2.526e-10
Identity = 42/61 (68.85%), Postives = 52/61 (85.25%), Query Frame = 1 
Query: 1000 EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  280 EEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 340
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Xenopus
Match: ubl4a (ubiquitin like 4A [Source:Xenbase;Acc:XB-GENE-6455973])

HSP 1 Score: 55.0694 bits (131), Expect = 6.935e-9
Identity = 41/61 (67.21%), Postives = 52/61 (85.25%), Query Frame = 1 
Query: 1000 EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            EE  +++E+RLLKNREAARECR+KKKEYVKCLENRVA LE QNK L++E+  +KD+Y  K+
Sbjct:   41 EEVTRKRELRLLKNREAARECRKKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKT 101
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Xenopus
Match: tars3 (threonyl-tRNA synthetase 3 [Source:Xenbase;Acc:XB-GENE-5954362])

HSP 1 Score: 58.5362 bits (140), Expect = 7.608e-9
Identity = 41/56 (73.21%), Postives = 49/56 (87.50%), Query Frame = 1 
Query: 1015 RKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            ++EIRLLKNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  K+
Sbjct:  225 KREIRLLKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYCHKT 280
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Mouse
Match: Creb1 (cAMP responsive element binding protein 1 [Source:MGI Symbol;Acc:MGI:88494])

HSP 1 Score: 63.929 bits (154), Expect = 1.238e-10
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  216 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 286
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Mouse
Match: Creb1 (cAMP responsive element binding protein 1 [Source:MGI Symbol;Acc:MGI:88494])

HSP 1 Score: 63.929 bits (154), Expect = 1.425e-10
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  256 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 326
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Mouse
Match: Creb1 (cAMP responsive element binding protein 1 [Source:MGI Symbol;Acc:MGI:88494])

HSP 1 Score: 63.929 bits (154), Expect = 1.425e-10
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  256 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 326
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Mouse
Match: Creb1 (cAMP responsive element binding protein 1 [Source:MGI Symbol;Acc:MGI:88494])

HSP 1 Score: 63.929 bits (154), Expect = 1.627e-10
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  270 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 340
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Mouse
Match: Creb1 (cAMP responsive element binding protein 1 [Source:MGI Symbol;Acc:MGI:88494])

HSP 1 Score: 63.929 bits (154), Expect = 1.627e-10
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  270 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 340
[Close]
BLAST of cAMP-responsive element modulator vs. UniProt/SwissProt
Match: sp|P27925|CREB1_BOVIN (Cyclic AMP-responsive element-binding protein 1 OS=Bos taurus OX=9913 GN=CREB1 PE=1 SV=2)

HSP 1 Score: 63.929 bits (154), Expect = 1.019e-9
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  254 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 324
[Close]
BLAST of cAMP-responsive element modulator vs. UniProt/SwissProt
Match: sp|P15337|CREB1_RAT (Cyclic AMP-responsive element-binding protein 1 OS=Rattus norvegicus OX=10116 GN=Creb1 PE=1 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 1.088e-9
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  270 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 340
[Close]
BLAST of cAMP-responsive element modulator vs. UniProt/SwissProt
Match: sp|Q01147|CREB1_MOUSE (Cyclic AMP-responsive element-binding protein 1 OS=Mus musculus OX=10090 GN=Creb1 PE=1 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 1.138e-9
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  270 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 340
[Close]
BLAST of cAMP-responsive element modulator vs. UniProt/SwissProt
Match: sp|P16220|CREB1_HUMAN (Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=2)

HSP 1 Score: 63.929 bits (154), Expect = 1.201e-9
Identity = 45/71 (63.38%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  976 SKPGLMNN--EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            S P L     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS
Sbjct:  270 SSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKS 340
[Close]
BLAST of cAMP-responsive element modulator vs. UniProt/SwissProt
Match: sp|P81269|ATF1_MOUSE (Cyclic AMP-dependent transcription factor ATF-1 OS=Mus musculus OX=10090 GN=Atf1 PE=1 SV=1)

HSP 1 Score: 62.003 bits (149), Expect = 2.651e-9
Identity = 43/56 (76.79%), Postives = 50/56 (89.29%), Query Frame = 1 
Query: 1015 RKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            R+EIRL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+YS KS
Sbjct:  213 RREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSHKS 268
[Close]
BLAST of cAMP-responsive element modulator vs. TrEMBL
Match: A0A3B4TYX1 (BZIP domain-containing protein OS=Seriola dumerili OX=41447 PE=4 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 5.532e-9
Identity = 46/73 (63.01%), Postives = 56/73 (76.71%), Query Frame = 1 
Query:  982 PGLMNN------EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            PG M N      EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K+
Sbjct:   33 PGTMQNPSSQHAEEITRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHKA 105
[Close]
BLAST of cAMP-responsive element modulator vs. TrEMBL
Match: A0A3B4WKI3 (cAMP responsive element modulator a OS=Seriola lalandi dorsalis OX=1841481 PE=4 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 1.971e-8
Identity = 46/74 (62.16%), Postives = 57/74 (77.03%), Query Frame = 1 
Query:  982 PGLMNN------EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            PG M N      EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K++
Sbjct:  183 PGTMQNPSSQHAEEITRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHKAE 256
[Close]
BLAST of cAMP-responsive element modulator vs. TrEMBL
Match: A0A3B3BAN1 (BZIP domain-containing protein OS=Oryzias melastigma OX=30732 PE=4 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 2.954e-8
Identity = 43/68 (63.24%), Postives = 55/68 (80.88%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            P   + EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K++
Sbjct:   44 PSSQHAEEITRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHKAE 111
[Close]
BLAST of cAMP-responsive element modulator vs. TrEMBL
Match: A0A3B3IGV4 (BZIP domain-containing protein OS=Oryzias latipes OX=8090 GN=LOC101157884 PE=4 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 2.954e-8
Identity = 43/68 (63.24%), Postives = 55/68 (80.88%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            P   + EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K++
Sbjct:   44 PSSQHAEEITRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHKAE 111
[Close]
BLAST of cAMP-responsive element modulator vs. TrEMBL
Match: A0A3P9KGX9 (BZIP domain-containing protein OS=Oryzias latipes OX=8090 PE=4 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 2.954e-8
Identity = 43/68 (63.24%), Postives = 55/68 (80.88%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            P   + EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K++
Sbjct:   44 PSSQHAEEITRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHKAE 111
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Cavefish
Match: ENSAMXT00000045163.1 (cyclic AMP-responsive element-binding protein 1-like [Source:NCBI gene;Acc:103024012])

HSP 1 Score: 62.7734 bits (151), Expect = 1.647e-10
Identity = 43/67 (64.18%), Postives = 54/67 (80.60%), Query Frame = 1 
Query:  985 GLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            G    EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  202 GQGGAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 268
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Cavefish
Match: creb1b (cAMP responsive element binding protein 1 [Source:NCBI gene;Acc:103036831])

HSP 1 Score: 62.7734 bits (151), Expect = 1.744e-10
Identity = 43/68 (63.24%), Postives = 54/68 (79.41%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            P     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  208 PSQGGAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 275
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Cavefish
Match: creb1b (cAMP responsive element binding protein 1 [Source:NCBI gene;Acc:103036831])

HSP 1 Score: 63.5438 bits (153), Expect = 1.931e-10
Identity = 43/68 (63.24%), Postives = 54/68 (79.41%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            P     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  267 PSQGGAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 334
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Cavefish
Match: ENSAMXT00000052688.1 (cyclic AMP-responsive element-binding protein 1-like [Source:NCBI gene;Acc:103024012])

HSP 1 Score: 63.1586 bits (152), Expect = 1.934e-10
Identity = 43/67 (64.18%), Postives = 54/67 (80.60%), Query Frame = 1 
Query:  985 GLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            G    EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  253 GQGGAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 319
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Cavefish
Match: crema (cAMP responsive element modulator a [Source:ZFIN;Acc:ZDB-GENE-030131-7031])

HSP 1 Score: 62.003 bits (149), Expect = 2.425e-10
Identity = 44/71 (61.97%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  982 PGLMNN-----EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKK 1179
            PG +++     EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K
Sbjct:  180 PGAIHSPQQQAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHK 250
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000478.1 (pep scaffold:Pmarinus_7.0:GL478554:185228:188045:1 gene:ENSPMAG00000000425.1 transcript:ENSPMAT00000000478.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.5362 bits (140), Expect = 9.877e-10
Identity = 40/62 (64.52%), Postives = 52/62 (83.87%), Query Frame = 1 
Query: 1000 EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            EE  +++E+RL+KNREAARECRRKKKEYVKCLENRV  LE QNK L++E+  +KD+Y  K++
Sbjct:  219 EEGTRKREVRLMKNREAARECRRKKKEYVKCLENRVTVLENQNKTLIEELKALKDLYCHKAE 280
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006902.1 (pep scaffold:Pmarinus_7.0:GL479181:8648:17720:-1 gene:ENSPMAG00000006211.1 transcript:ENSPMAT00000006902.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.151 bits (139), Expect = 1.614e-9
Identity = 40/64 (62.50%), Postives = 53/64 (82.81%), Query Frame = 1 
Query:  991 MNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKS 1182
            ++ E   +++EIRL+KNREAARECRRKKKEYVKCLENR+A LE QNK L++E+  +KD+Y  K+
Sbjct:  255 IHEEPVTRKREIRLMKNREAARECRRKKKEYVKCLENRLAVLENQNKTLIEELKALKDLYCHKT 318
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006494.1 (pep scaffold:Pmarinus_7.0:GL478796:6798:14081:1 gene:ENSPMAG00000005844.1 transcript:ENSPMAT00000006494.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.5362 bits (140), Expect = 1.683e-9
Identity = 42/62 (67.74%), Postives = 50/62 (80.65%), Query Frame = 1 
Query:  994 NNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKK 1179
              EE  +++EIRL KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  K
Sbjct:  274 GAEESTRKREIRLYKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYCHK 335
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Nematostella
Match: EDO41380 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4F1])

HSP 1 Score: 61.2326 bits (147), Expect = 2.531e-10
Identity = 41/62 (66.13%), Postives = 53/62 (85.48%), Query Frame = 1 
Query: 1000 EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            EE  +++E+RL+KNREAA+ECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  236 EEATRKREMRLMKNREAAKECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 297
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Medaka
Match: ENSORLT00000027248.1 (cAMP-responsive element modulator [Source:NCBI gene;Acc:101157884])

HSP 1 Score: 62.7734 bits (151), Expect = 1.112e-11
Identity = 43/68 (63.24%), Postives = 55/68 (80.88%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            P   + EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K++
Sbjct:   44 PSSQHAEEITRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHKAE 111
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Medaka
Match: ENSORLT00000044925.1 (cAMP-responsive element modulator [Source:NCBI gene;Acc:101157884])

HSP 1 Score: 62.7734 bits (151), Expect = 4.206e-11
Identity = 43/68 (63.24%), Postives = 55/68 (80.88%), Query Frame = 1 
Query:  982 PGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            P   + EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KDIY  K++
Sbjct:  110 PSSQHAEEITRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDIYCHKAE 177
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Medaka
Match: ENSORLT00000002935.2 (cyclic AMP-responsive element-binding protein 1 [Source:NCBI gene;Acc:101158674])

HSP 1 Score: 63.5438 bits (153), Expect = 1.583e-10
Identity = 42/64 (65.62%), Postives = 53/64 (82.81%), Query Frame = 1 
Query:  994 NNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
              EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  252 GTEEVTRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 315
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Medaka
Match: ENSORLT00000002931.2 (cyclic AMP-responsive element-binding protein 1 [Source:NCBI gene;Acc:101158674])

HSP 1 Score: 62.7734 bits (151), Expect = 1.615e-10
Identity = 42/64 (65.62%), Postives = 53/64 (82.81%), Query Frame = 1 
Query:  994 NNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
              EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  203 GTEEVTRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 266
[Close]
BLAST of cAMP-responsive element modulator vs. Ensembl Medaka
Match: creb1b (cyclic AMP-responsive element-binding protein 1-like [Source:NCBI gene;Acc:101164105])

HSP 1 Score: 63.1586 bits (152), Expect = 2.475e-10
Identity = 42/62 (67.74%), Postives = 53/62 (85.48%), Query Frame = 1 
Query: 1000 EEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSK 1185
            EE  +++E+RL+KNREAARECRRKKKEYVKCLENRVA LE QNK L++E+  +KD+Y  KS+
Sbjct:  268 EEVTRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE 329
[Close]
BLAST of cAMP-responsive element modulator vs. Planmine SMEST
Match: SMESG000033655.1 (SMESG000033655.1)

HSP 1 Score: 828.55 bits (2139), Expect = 0.000e+0
Identity = 513/513 (100.00%), Postives = 513/513 (100.00%), Query Frame = 1 
Query:  112 MSFDDSHQYLIAIPNANGESQTIIFTPEVLPEQLIPLVQKKHLKEEKSDYSNLSSVYKKIXXXXXXXXXXXXXXXIDVSSIVNLGDKPKISNAESITDSINSKNINSTAPSIIRNLQANLNSGSSLPTTFXXXXXXXXXXXXXXXXXXXXTGHSENSSNYITTIQISQNNSNLSTLAFNQPQALLHYSKQNQDSQNTVLIPISLQNSNQYTQQQIIVAAGGYNQNCGESVNNTISSNSNHSESLNVTSLAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKLTHKSKPGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSKPTLHILNPDMNNKFMDVYSSDNAMKEDIFDSATEENSQISSIDKSYSITISGNTQTSTTSDVNNFNISKSKLHPTHLDNSRVIINASNLSTNKDSQNLLLKLKKENTSALSLLLSGDHKPYNQQVFEPNSIIFPESLHESNPIDYNNSRNNCDSN 1650
            MSFDDSHQYLIAIPNANGESQTIIFTPEVLPEQLIPLVQKKHLKEEKSDYSNLSSVYKKILENLESGNSSNLSNLIDVSSIVNLGDKPKISNAESITDSINSKNINSTAPSIIRNLQANLNSGSSLPTTFLLQTSNLNQNSQNLGSSSDQTGHSENSSNYITTIQISQNNSNLSTLAFNQPQALLHYSKQNQDSQNTVLIPISLQNSNQYTQQQIIVAAGGYNQNCGESVNNTISSNSNHSESLNVTSLAKLISSNCSNPLSISLNNLPNKSNSSCSEVSPNSKLTHKSKPGLMNNEEFGKRKEIRLLKNREAARECRRKKKEYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSKPTLHILNPDMNNKFMDVYSSDNAMKEDIFDSATEENSQISSIDKSYSITISGNTQTSTTSDVNNFNISKSKLHPTHLDNSRVIINASNLSTNKDSQNLLLKLKKENTSALSLLLSGDHKPYNQQVFEPNSIIFPESLHESNPIDYNNSRNNCDSN
Sbjct:    1 MSFDDSHQYLIAIPNANGESQTIIFTPEVLPEQLIPLVQKKHLKEEKSDYSNLSSVYKKILENLESGNSSNLSNLIDVSSIVNLGDKPKISNAESITDSINSKNINSTAPSIIRNLQANLNSGSSLPTTFLLQTSNLNQNSQNLGSSSDQTGHSENSSNYITTIQISQNNSNLSTLAFNQPQALLHYSKQNQDSQNTVLIPISLQNSNQYTQQQIIVAAGGYNQNCGESVNNTISSNSNHSESLNVTSLAKLISSNCSNPLSISLNNLPNKSNSSCSEVSPNSKLTHKSKPGLMNNEEFGKRKEIRLLKNREAARECRRKKKEYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSKPTLHILNPDMNNKFMDVYSSDNAMKEDIFDSATEENSQISSIDKSYSITISGNTQTSTTSDVNNFNISKSKLHPTHLDNSRVIINASNLSTNKDSQNLLLKLKKENTSALSLLLSGDHKPYNQQVFEPNSIIFPESLHESNPIDYNNSRNNCDSN 513
[Close]
BLAST of cAMP-responsive element modulator vs. Planmine SMEST
Match: SMESG000033655.1 (SMESG000033655.1)

HSP 1 Score: 826.239 bits (2133), Expect = 0.000e+0
Identity = 487/513 (94.93%), Postives = 488/513 (95.13%), Query Frame = 1 
Query:  112 MSFDDSHQYLIAIPNANGESQTIIFTPEVLPEQLIPLVQKKHLKEEKSDYSNLSSVYKKIXXXXXXXXXXXXXXXIDVSSIVNLGDKPKISNAESITDSINSKNINSTAPSIIRNLQANLNSGSSLPTTFXXXXXXXXXXXXXXXXXXXXTGHSENSSNYITTIQISQNNSNLSTLAFNQPQALLHYSKQNQDSQNTVLIPISLQNSNQYTQQQIIVAAGGYNQNCGESVNNTISSNSNHSESLNVTSLAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKLTHKSKPGLMNNEEFGKRKEIRLLXXXXXXXXXXXXXXXYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSKPTLHILNPDMNNKFMDVYSSDNAMKEDIFDSATEENSQISSIDKSYSITISGNTQTSTTSDVNNFNISKSKLHPTHLDNSRVIINASNLSTNKDSQNLLLKLKKENTSALSLLLSGDHKPYNQQVFEPNSIIFPESLHESNPIDYNNSRNNCDSN 1650
            MSFDDSHQYLIAIPNANGESQTIIFTPEVLPEQLIPLVQKKHLKEEKSDYSNLSSVYKKILENLESGNSSNLSNLIDVSSIVNLGDKPKISNAESITDSINSKNINSTAPSIIRNLQANLNSGSSLPTTFLLQTSNLNQNSQNLGSSSDQTGHSENSSNYITTIQISQNNSNLSTLAFNQPQALLHYSKQNQDSQNTVLIPISLQNSNQYTQQQIIVAAGGYNQNCGESVNNTISSNSNHSESLNVTSLAKLISSNC    +                     KLTHKSKPGLMNNEEFGKRKEIRLLKNREAARECRRKKKEYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSKPTLHILNPDMNNKFMDVYSSDNAMKEDIFDSATEENSQISSIDKSYSITISGNTQTSTTSDVNNFNISKSKLHPTHLDNSRVIINASNLSTNKDSQNLLLKLKKENTSALSLLLSGDHKPYNQQVFEPNSIIFPESLHESNPIDYNNSRNNCDSN
Sbjct:    1 MSFDDSHQYLIAIPNANGESQTIIFTPEVLPEQLIPLVQKKHLKEEKSDYSNLSSVYKKILENLESGNSSNLSNLIDVSSIVNLGDKPKISNAESITDSINSKNINSTAPSIIRNLQANLNSGSSLPTTFLLQTSNLNQNSQNLGSSSDQTGHSENSSNYITTIQISQNNSNLSTLAFNQPQALLHYSKQNQDSQNTVLIPISLQNSNQYTQQQIIVAAGGYNQNCGESVNNTISSNSNHSESLNVTSLAKLISSNCKVSPNS--------------------KLTHKSKPGLMNNEEFGKRKEIRLLKNREAARECRRKKKEYVKCLENRVANLEQQNKVLVDEINRMKDIYSKKSKPTLHILNPDMNNKFMDVYSSDNAMKEDIFDSATEENSQISSIDKSYSITISGNTQTSTTSDVNNFNISKSKLHPTHLDNSRVIINASNLSTNKDSQNLLLKLKKENTSALSLLLSGDHKPYNQQVFEPNSIIFPESLHESNPIDYNNSRNNCDSN 493
The following BLAST results are available for this feature:
BLAST of cAMP-responsive element modulator vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CREB12.021e-1063.38cAMP responsive element binding protein 1 [Source:... [more]
CREB12.021e-1063.38cAMP responsive element binding protein 1 [Source:... [more]
CREB12.501e-1063.38cAMP responsive element binding protein 1 [Source:... [more]
ATF12.324e-975.00activating transcription factor 1 [Source:HGNC Sym... [more]
CREM2.662e-968.33cAMP responsive element modulator [Source:HGNC Sym... [more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
crh-14.132e-959.09CREB Homolog; Cyclic AMP-response element binding ... [more]
crh-16.821e-959.09CREB Homolog; Cyclic AMP-response element binding ... [more]
crh-18.187e-959.09CREB Homolog; Cyclic AMP-response element binding ... [more]
crh-19.406e-959.09CREB Homolog; Cyclic AMP-response element binding ... [more]
crh-19.552e-959.09CREB Homolog; Cyclic AMP-response element binding ... [more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CrebB1.383e-756.00gene:FBgn0265784 transcript:FBtr0346093[more]
CrebB1.383e-756.00gene:FBgn0265784 transcript:FBtr0310341[more]
CrebB1.383e-756.00gene:FBgn0265784 transcript:FBtr0112879[more]
CrebB1.615e-756.00gene:FBgn0265784 transcript:FBtr0074557[more]
CrebB2.403e-764.41gene:FBgn0265784 transcript:FBtr0310340[more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
crema2.162e-1162.67cAMP responsive element modulator a [Source:ZFIN;A... [more]
crema1.758e-1064.38cAMP responsive element modulator a [Source:ZFIN;A... [more]
creb1b1.994e-1063.24cAMP responsive element binding protein 1b [Source... [more]
creb1a2.547e-1062.50cAMP responsive element binding protein 1a [Source... [more]
creb1a2.547e-1062.50cAMP responsive element binding protein 1a [Source... [more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ubl4a1.595e-1064.18ubiquitin like 4A [Source:Xenbase;Acc:XB-GENE-6455... [more]
det12.023e-1068.85DET1, COP1 ubiquitin ligase partner [Source:Xenbas... [more]
det12.526e-1068.85DET1, COP1 ubiquitin ligase partner [Source:Xenbas... [more]
ubl4a6.935e-967.21ubiquitin like 4A [Source:Xenbase;Acc:XB-GENE-6455... [more]
tars37.608e-973.21threonyl-tRNA synthetase 3 [Source:Xenbase;Acc:XB-... [more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Creb11.238e-1063.38cAMP responsive element binding protein 1 [Source:... [more]
Creb11.425e-1063.38cAMP responsive element binding protein 1 [Source:... [more]
Creb11.425e-1063.38cAMP responsive element binding protein 1 [Source:... [more]
Creb11.627e-1063.38cAMP responsive element binding protein 1 [Source:... [more]
Creb11.627e-1063.38cAMP responsive element binding protein 1 [Source:... [more]
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BLAST of cAMP-responsive element modulator vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P27925|CREB1_BOVIN1.019e-963.38Cyclic AMP-responsive element-binding protein 1 OS... [more]
sp|P15337|CREB1_RAT1.088e-963.38Cyclic AMP-responsive element-binding protein 1 OS... [more]
sp|Q01147|CREB1_MOUSE1.138e-963.38Cyclic AMP-responsive element-binding protein 1 OS... [more]
sp|P16220|CREB1_HUMAN1.201e-963.38Cyclic AMP-responsive element-binding protein 1 OS... [more]
sp|P81269|ATF1_MOUSE2.651e-976.79Cyclic AMP-dependent transcription factor ATF-1 OS... [more]
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BLAST of cAMP-responsive element modulator vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3B4TYX15.532e-963.01BZIP domain-containing protein OS=Seriola dumerili... [more]
A0A3B4WKI31.971e-862.16cAMP responsive element modulator a OS=Seriola lal... [more]
A0A3B3BAN12.954e-863.24BZIP domain-containing protein OS=Oryzias melastig... [more]
A0A3B3IGV42.954e-863.24BZIP domain-containing protein OS=Oryzias latipes ... [more]
A0A3P9KGX92.954e-863.24BZIP domain-containing protein OS=Oryzias latipes ... [more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000045163.11.647e-1064.18cyclic AMP-responsive element-binding protein 1-li... [more]
creb1b1.744e-1063.24cAMP responsive element binding protein 1 [Source:... [more]
creb1b1.931e-1063.24cAMP responsive element binding protein 1 [Source:... [more]
ENSAMXT00000052688.11.934e-1064.18cyclic AMP-responsive element-binding protein 1-li... [more]
crema2.425e-1061.97cAMP responsive element modulator a [Source:ZFIN;A... [more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000000478.19.877e-1064.52pep scaffold:Pmarinus_7.0:GL478554:185228:188045:1... [more]
ENSPMAT00000006902.11.614e-962.50pep scaffold:Pmarinus_7.0:GL479181:8648:17720:-1 g... [more]
ENSPMAT00000006494.11.683e-967.74pep scaffold:Pmarinus_7.0:GL478796:6798:14081:1 ge... [more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of cAMP-responsive element modulator vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO413802.531e-1066.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of cAMP-responsive element modulator vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000027248.11.112e-1163.24cAMP-responsive element modulator [Source:NCBI gen... [more]
ENSORLT00000044925.14.206e-1163.24cAMP-responsive element modulator [Source:NCBI gen... [more]
ENSORLT00000002935.21.583e-1065.63cyclic AMP-responsive element-binding protein 1 [S... [more]
ENSORLT00000002931.21.615e-1065.63cyclic AMP-responsive element-binding protein 1 [S... [more]
creb1b2.475e-1067.74cyclic AMP-responsive element-binding protein 1-li... [more]
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BLAST of cAMP-responsive element modulator vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000033655.10.000e+0100.00SMESG000033655.1[more]
SMESG000033655.10.000e+094.93SMESG000033655.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015409 ID=SMED30015409|Name=cAMP-responsive element modulator|organism=Schmidtea mediterranea sexual|type=transcript|length=1844bp
TAACCTTGTAAGTTATGACGCCAAATTGACGTCCTCAAGATTGTTATGAC
GTGACAGCCATCTTGATTAAGAGTGGTTAATTTTTTAATACATATTTCAA
GCTAACTTTAAATGTCGTTTGATGATAGTCATCAATATCTGATAGCAATA
CCTAATGCGAATGGAGAATCACAAACAATTATTTTTACTCCTGAAGTTTT
ACCGGAACAATTAATACCATTAGTGCAAAAGAAGCACTTAAAAGAAGAAA
AGTCTGATTATTCCAACTTAAGTTCTGTTTATAAGAAAATTCTTGAAAAT
TTAGAGAGTGGAAATTCAAGTAATTTGAGTAATTTAATAGATGTAAGTTC
TATTGTAAATCTTGGTGACAAACCGAAAATATCCAACGCAGAATCTATTA
CTGATAGCATCAATTCTAAAAATATCAATTCTACTGCTCCTTCAATAATT
CGAAATCTTCAAGCTAATCTCAATTCCGGTTCATCCCTACCAACAACCTT
TCTTTTACAGACATCAAATTTAAACCAAAACTCACAGAATCTAGGATCAT
CGAGTGATCAAACTGGCCATTCTGAAAATTCGTCGAATTACATAACAACC
ATACAAATATCGCAAAACAATTCTAATCTATCTACTCTGGCATTTAATCA
GCCTCAAGCATTGTTACATTATTCAAAGCAAAATCAAGATTCTCAAAATA
CAGTTTTGATACCAATATCACTTCAAAATTCTAATCAATATACTCAACAA
CAAATAATCGTTGCTGCCGGAGGTTATAATCAAAATTGTGGAGAAAGTGT
TAACAATACTATATCATCTAATTCCAATCATTCTGAATCTTTAAATGTCA
CATCTTTAGCGAAATTAATTTCTAGTAATTGTAGTAATCCTCTTTCAATC
AGTTTAAATAATCTTCCAAATAAATCGAATTCGTCGTGTTCAGAAGTATC
TCCGAATTCTAAATTGACACACAAATCAAAACCAGGATTAATGAATAACG
AAGAGTTTGGGAAGCGTAAAGAAATTAGATTGTTGAAAAATAGAGAGGCA
GCTAGAGAATGTCGACGAAAAAAGAAAGAATATGTAAAGTGTTTAGAAAA
CAGAGTCGCAAACCTGGAACAACAAAATAAAGTGTTAGTCGATGAAATCA
ATAGAATGAAAGATATTTATTCAAAAAAATCCAAGCCTACCTTACACATT
TTAAATCCTGATATGAACAATAAATTCATGGATGTTTATTCTTCTGATAA
TGCAATGAAAGAAGATATTTTTGATTCAGCGACTGAAGAAAATAGTCAAA
TATCATCCATAGATAAATCCTATTCCATAACTATTTCTGGAAATACACAA
ACTAGCACCACATCGGATGTTAATAATTTCAACATTTCCAAATCAAAATT
GCATCCAACGCATCTTGATAATTCTCGCGTAATTATAAATGCTTCGAATT
TGTCGACAAATAAAGATAGTCAAAATTTATTATTAAAATTGAAAAAAGAA
AACACTTCCGCTCTGTCATTATTACTGTCAGGGGATCATAAGCCGTATAA
TCAACAAGTATTTGAACCGAATTCGATTATTTTCCCAGAAAGCTTGCACG
AATCCAATCCTATTGACTATAATAATTCTAGAAACAATTGTGATTCAAAT
TGAGTATATTTTGATATGTATATATATAATATGTATGTATATATATATAA
TAAAATATTACGTATTGCAAAGTAATTAGAAAAGATTCAAATGGTCTCAT
CAAAAAGCCATGTATATATAATTTTATCACTTTTTTGCTTTATTTTAATT
TGAGATTGAAAAATATTTTCTGAAGCCCGTTTGATAATAAATTG
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protein sequence of SMED30015409-orf-1

>SMED30015409-orf-1 ID=SMED30015409-orf-1|Name=SMED30015409-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=514bp
MSFDDSHQYLIAIPNANGESQTIIFTPEVLPEQLIPLVQKKHLKEEKSDY
SNLSSVYKKILENLESGNSSNLSNLIDVSSIVNLGDKPKISNAESITDSI
NSKNINSTAPSIIRNLQANLNSGSSLPTTFLLQTSNLNQNSQNLGSSSDQ
TGHSENSSNYITTIQISQNNSNLSTLAFNQPQALLHYSKQNQDSQNTVLI
PISLQNSNQYTQQQIIVAAGGYNQNCGESVNNTISSNSNHSESLNVTSLA
KLISSNCSNPLSISLNNLPNKSNSSCSEVSPNSKLTHKSKPGLMNNEEFG
KRKEIRLLKNREAARECRRKKKEYVKCLENRVANLEQQNKVLVDEINRMK
DIYSKKSKPTLHILNPDMNNKFMDVYSSDNAMKEDIFDSATEENSQISSI
DKSYSITISGNTQTSTTSDVNNFNISKSKLHPTHLDNSRVIINASNLSTN
KDSQNLLLKLKKENTSALSLLLSGDHKPYNQQVFEPNSIIFPESLHESNP
IDYNNSRNNCDSN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR004827bZIP
Vocabulary: molecular function
TermDefinition
GO:0043565sequence-specific DNA binding
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0035035histone acetyltransferase binding
GO:0035497cAMP response element binding
GO:0042802identical protein binding
GO:0044212transcription regulatory region DNA binding
GO:0001190transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0003677DNA binding
GO:0003690double-stranded DNA binding
GO:0003705transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515protein binding
GO:0008134transcription factor binding
GO:0019899enzyme binding
GO:0030544Hsp70 protein binding
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001102RNA polymerase II activating transcription factor binding
GO:1990763arrestin family protein binding
GO:0000975regulatory region DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0035094response to nicotine
GO:0035729cellular response to hepatocyte growth factor stimulus
GO:0036120cellular response to platelet-derived growth factor stimulus
GO:0040018positive regulation of multicellular organism growth
GO:0042493response to drug
GO:0042752regulation of circadian rhythm
GO:0042981regulation of apoptotic process
GO:0043065positive regulation of apoptotic process
GO:0045600positive regulation of fat cell differentiation
GO:0045672positive regulation of osteoclast differentiation
GO:0045893positive regulation of transcription, DNA-templated
GO:0045899positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0045944positive regulation of transcription from RNA polymerase II promoter
GO:0046887positive regulation of hormone secretion
GO:0046889positive regulation of lipid biosynthetic process
GO:0048145regulation of fibroblast proliferation
GO:0048511rhythmic process
GO:0050821protein stabilization
GO:0055025positive regulation of cardiac muscle tissue development
GO:0060251regulation of glial cell proliferation
GO:0060428lung epithelium development
GO:0060430lung saccule development
GO:0060509Type I pneumocyte differentiation
GO:0071294cellular response to zinc ion
GO:0071363cellular response to growth factor stimulus
GO:0071398cellular response to fatty acid
GO:0071560cellular response to transforming growth factor beta stimulus
GO:1900273positive regulation of long-term synaptic potentiation
GO:1901215negative regulation of neuron death
GO:1902065response to L-glutamate
GO:1990090cellular response to nerve growth factor stimulus
GO:0001666response to hypoxia
GO:0006351transcription, DNA-templated
GO:0006366transcription from RNA polymerase II promoter
GO:0006468protein phosphorylation
GO:0007179transforming growth factor beta receptor signaling pathway
GO:0007409axonogenesis
GO:0007568aging
GO:0007595lactation
GO:0007613memory
GO:0007623circadian rhythm
GO:0008361regulation of cell size
GO:0008542visual learning
GO:0010033response to organic substance
GO:0010629negative regulation of gene expression
GO:0010944negative regulation of transcription by competitive promoter binding
GO:0014823response to activity
GO:0021983pituitary gland development
GO:0030154cell differentiation
GO:0030879mammary gland development
GO:0032916positive regulation of transforming growth factor beta3 production
GO:0033363secretory granule organization
GO:0033762response to glucagon
GO:0034670chemotaxis to arachidonic acid
GO:1990314cellular response to insulin-like growth factor stimulus
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005667transcription factor complex
GO:0005719nuclear euchromatin
GO:0005739mitochondrion
GO:0005759mitochondrial matrix
GO:0030424axon
GO:1990589ATF4-CREB1 transcription factor complex
GO:0000785chromatin
GO:0000790nuclear chromatin
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 318..352
NoneNo IPR availableGENE3DG3DSA:1.20.5.170coord: 302..356
e-value: 1.3E-17
score: 65.5
NoneNo IPR availablePANTHERPTHR45879:SF3CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN Bcoord: 149..358
NoneNo IPR availablePANTHERPTHR45879FAMILY NOT NAMEDcoord: 149..358
NoneNo IPR availableCDDcd14690bZIP_CREB1coord: 302..356
e-value: 8.34091E-24
score: 92.3091
NoneNo IPR availableSUPERFAMILYSSF57959Leucine zipper domaincoord: 302..352
IPR004827Basic-leucine zipper domainSMARTSM00338brlzneucoord: 298..362
e-value: 2.5E-10
score: 50.3
IPR004827Basic-leucine zipper domainPFAMPF00170bZIP_1coord: 302..356
e-value: 3.0E-16
score: 59.2
IPR004827Basic-leucine zipper domainPROSITEPS00036BZIP_BASICcoord: 306..320
IPR004827Basic-leucine zipper domainPROSITEPS50217BZIPcoord: 300..351
score: 10.818