bax-1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015261 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of bax-1 vs. Ensembl Human
Match: BAX (BCL2 associated X, apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:959]) HSP 1 Score: 52.7582 bits (125), Expect = 7.973e-8 Identity = 30/102 (29.41%), Postives = 50/102 (49.02%), Query Frame = 2 Query: 677 SDSSDWLRTNALQMNQM----DKIQARQELNKIFLSIFSE-KINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 + S ++T AL + M D R+ ++ +FS+ NWGR+VA+ F +L A +LI + ++ F+ E L WI GGW+GL+ + Sbjct: 14 TSSEQIMKTGALLLQGMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSY 115
BLAST of bax-1 vs. Ensembl Human
Match: BAX (BCL2 associated X, apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:959]) HSP 1 Score: 50.0618 bits (118), Expect = 5.973e-7 Identity = 25/82 (30.49%), Postives = 42/82 (51.22%), Query Frame = 2 Query: 725 MDKIQARQELNKIFLSIFSE-KINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 +D R+ ++ +FS+ NWGR+VA+ F +L A +LI + ++ F+ E L WI GGW+GL+ + Sbjct: 17 VDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSY 98
BLAST of bax-1 vs. Ensembl Human
Match: BAX (BCL2 associated X, apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:959]) HSP 1 Score: 50.8322 bits (120), Expect = 6.567e-7 Identity = 34/130 (26.15%), Postives = 60/130 (46.15%), Query Frame = 2 Query: 593 QCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQM----DKIQARQELNKIFLSIFSEK-INWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 + AL P D K L +K ++ +S+ +++ +M D R+ ++ +FS+ NWGR+VA+ F +L A +LI + ++ F+ E L WI GGW+GL+ + Sbjct: 27 ELALDPVPQDASTKKLSECLKRIGDELDSN---------MELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSY 147
BLAST of bax-1 vs. Ensembl Human
Match: BAX (BCL2 associated X, apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:959]) HSP 1 Score: 50.447 bits (119), Expect = 1.205e-6 Identity = 34/130 (26.15%), Postives = 60/130 (46.15%), Query Frame = 2 Query: 593 QCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQM----DKIQARQELNKIFLSIFSEK-INWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 + AL P D K L +K ++ +S+ +++ +M D R+ ++ +FS+ NWGR+VA+ F +L A +LI + ++ F+ E L WI GGW+GL+ + Sbjct: 44 ELALDPVPQDASTKKLSECLKRIGDELDSN---------MELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSY 164
BLAST of bax-1 vs. Ensembl Zebrafish
Match: baxa (BCL2 associated X, apoptosis regulator a [Source:ZFIN;Acc:ZDB-GENE-000511-6]) HSP 1 Score: 56.225 bits (134), Expect = 9.631e-9 Identity = 24/71 (33.80%), Postives = 42/71 (59.15%), Query Frame = 2 Query: 758 KIFLSIFSE-KINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 ++ IFS+ K NWGR+VA+ F C L A D+I + ++S++ E++ +WI + GGW+G+ + Sbjct: 96 RVAREIFSDGKFNWGRVVALFYFACRLVIKAISTRVPDIIRTIISWTMSYIQEHVINWIREQGGWDGIRSY 166
BLAST of bax-1 vs. Ensembl Zebrafish
Match: zgc:153993 (zgc:153993 [Source:ZFIN;Acc:ZDB-GENE-060929-176]) HSP 1 Score: 50.447 bits (119), Expect = 8.225e-7 Identity = 23/68 (33.82%), Postives = 38/68 (55.88%), Query Frame = 2 Query: 770 SIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQT 973 SIF + INWGR+VA+ L A + ++I+ + + F+ +++ +WI Q GGWEG+ T Sbjct: 113 SIFDDGINWGRVVALFHLAYRLIFQALTQNHLEIIKNIISWFLQFMKKHISAWIRQQGGWEGIFRSMT 180
BLAST of bax-1 vs. Ensembl Xenopus
Match: bax (BCL2-associated X protein [Source:NCBI gene;Acc:394793]) HSP 1 Score: 52.373 bits (124), Expect = 3.047e-7 Identity = 21/66 (31.82%), Postives = 39/66 (59.09%), Query Frame = 2 Query: 773 IFSEKI-NWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 +F++ + NWGR+VA+ F C+L A ++I + ++ ++ EY+ WI GGWEG++ + Sbjct: 118 LFADGVFNWGRVVALFYFACKLVVKALCTKVPEMIRTIINWTMEYLREYVVQWIRDQGGWEGMLSY 183
BLAST of bax-1 vs. Ensembl Xenopus
Match: bax (BCL2-associated X protein [Source:NCBI gene;Acc:394793]) HSP 1 Score: 52.373 bits (124), Expect = 4.064e-7 Identity = 21/66 (31.82%), Postives = 39/66 (59.09%), Query Frame = 2 Query: 773 IFSEKI-NWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 +F++ + NWGR+VA+ F C+L A ++I + ++ ++ EY+ WI GGWEG++ + Sbjct: 129 LFADGVFNWGRVVALFYFACKLVVKALCTKVPEMIRTIINWTMEYLREYVVQWIRDQGGWEGMLSY 194
BLAST of bax-1 vs. Ensembl Mouse
Match: Bax (BCL2-associated X protein [Source:MGI Symbol;Acc:MGI:99702]) HSP 1 Score: 47.7506 bits (112), Expect = 4.735e-6 Identity = 22/59 (37.29%), Postives = 32/59 (54.24%), Query Frame = 2 Query: 791 NWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 NWGR+VA+ F +L A +LI + ++ F+ E L WI GGWEGL+ + Sbjct: 87 NWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSY 145
BLAST of bax-1 vs. Ensembl Mouse
Match: Bax (BCL2-associated X protein [Source:MGI Symbol;Acc:MGI:99702]) HSP 1 Score: 48.1358 bits (113), Expect = 5.359e-6 Identity = 25/82 (30.49%), Postives = 42/82 (51.22%), Query Frame = 2 Query: 725 MDKIQARQELNKIFLSIFSEK-INWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 +D R+ ++ +F++ NWGR+VA+ F +L A +LI + ++ F+ E L WI GGWEGL+ + Sbjct: 83 VDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSY 164
BLAST of bax-1 vs. UniProt/SwissProt
Match: sp|Q07812|BAX_HUMAN (Apoptosis regulator BAX OS=Homo sapiens OX=9606 GN=BAX PE=1 SV=1) HSP 1 Score: 50.447 bits (119), Expect = 5.786e-6 Identity = 34/130 (26.15%), Postives = 60/130 (46.15%), Query Frame = 2 Query: 593 QCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQM----DKIQARQELNKIFLSIFSEK-INWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 + AL P D K L +K ++ +S+ +++ +M D R+ ++ +FS+ NWGR+VA+ F +L A +LI + ++ F+ E L WI GGW+GL+ + Sbjct: 44 ELALDPVPQDASTKKLSECLKRIGDELDSN---------MELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSY 164
BLAST of bax-1 vs. TrEMBL
Match: H2DL15 (Bax-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 624.394 bits (1609), Expect = 0.000e+0 Identity = 335/336 (99.70%), Postives = 336/336 (100.00%), Query Frame = 2 Query: 86 MGDYDTDDELKNDAHFDDSIPSMESESICDRITNNSSNATPVNNGDDYXXXXXXXXXXXXXXCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQTGQSGSNNELENIFXXXXXXXXXXXXXXXXXXFCKYVADHI 1093 MGDYDTDDELKNDAHFDDSIPSME+ESICDRITNNSSNATPVNNGDDYSSSNSHRNHRHNPRCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQTGQSGSNNELENIFSSLSRIARVAALALAGVAFCKYVADHI Sbjct: 1 MGDYDTDDELKNDAHFDDSIPSMEAESICDRITNNSSNATPVNNGDDYSSSNSHRNHRHNPRCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQTGQSGSNNELENIFSSLSRIARVAALALAGVAFCKYVADHI 336
BLAST of bax-1 vs. TrEMBL
Match: A0A182YTM2 (BH4_2 domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106067260 PE=4 SV=1) HSP 1 Score: 68.9366 bits (167), Expect = 9.726e-10 Identity = 39/114 (34.21%), Postives = 62/114 (54.39%), Query Frame = 2 Query: 635 SLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQTG 976 ++ L FEE+F+S D + Q+N D+ A + I IFS+ INWGRIVA+ GF + + +++ L++ + ++VD L SW+ H W+G MEFQ+G Sbjct: 64 AMRTLGDEFEERFSSRFDDLIN----QLNINDE-NAYETYTAIVNEIFSDSINWGRIVALFGFSGRFAVRCYELNKTHLVDNLLEWLTTYVDTRLSSWMNTHNNWQGFMEFQSG 172
BLAST of bax-1 vs. TrEMBL
Match: A0A1D1VDS4 (Uncharacterized protein OS=Ramazzottius varieornatus OX=947166 GN=RvY_10015-1 PE=4 SV=1) HSP 1 Score: 67.3958 bits (163), Expect = 1.453e-8 Identity = 37/124 (29.84%), Postives = 71/124 (57.26%), Query Frame = 2 Query: 599 ALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQ 970 AL D ++++S E + + F+S++++ LR L M+Q D Q++ +++ EKINWGRI+ F +L++ A + +++L+ + F+ +L +WI HGGWEGL++++ Sbjct: 159 ALGDHLDSRYWQSFEE--AFPADWFDSNTTEELRNRFLDMSQ-DLYSNVQDVED--EALYEEKINWGRIITHFCFTSQLATVAVLSKQYELVNQLTGWLTQFITLHLRTWIEHHGGWEGLVDYR 277
BLAST of bax-1 vs. TrEMBL
Match: A0A0B7AMK5 (BH4_2 domain-containing protein OS=Arion vulgaris OX=1028688 GN=ORF124635 PE=4 SV=1) HSP 1 Score: 64.3142 bits (155), Expect = 4.151e-8 Identity = 40/147 (27.21%), Postives = 65/147 (44.22%), Query Frame = 2 Query: 563 KQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQTGQSGSNNELE 1003 +Q+ PN Q A+ DD FEE++NS D +Q + A I IF++ +NWGR++A+ GF + F ++++ V ++VD L W+ H W+G MEFQ Q S +++ Sbjct: 45 RQSNITPNPVQSAMRRLGDD------------FEERYNSRFVD-----MIQKLNITSDNASDTFTAIMDEIFTDGVNWGRVIALFGFSGRFAVYCFEHDMDEMVDHIVELVTAYVDNTLRDWMLNHNNWQGFMEFQAVQPESEKDIQ 174
BLAST of bax-1 vs. TrEMBL
Match: A0A2T7PBP0 (BH4_2 domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_10104 PE=4 SV=1) HSP 1 Score: 63.929 bits (154), Expect = 5.035e-8 Identity = 42/140 (30.00%), Postives = 63/140 (45.00%), Query Frame = 2 Query: 557 KLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQTG 976 +L++N N Q + P ++ +++ L FE KF++ D + Q+ A Q I IF + +NWGRIVA+ G L+ + LIE V ++VD L WI H GW G +EF G Sbjct: 27 RLERNGLAWQNGQRDVTP---NEIQRAMRALGDEFESKFSAQFDD-----MMSQLQLTPDTAYQTFRTIVTEIFHDGVNWGRIVALFGLAGRLAVLSSHQEMPRLIESIVDWVSAYVDTNLKQWITDHDGWAGFLEFYAG 158
BLAST of bax-1 vs. Ensembl Cavefish
Match: ENSAMXT00000005311.2 (pep primary_assembly:Astyanax_mexicanus-2.0:2:7917921:7922418:1 gene:ENSAMXG00000005183.2 transcript:ENSAMXT00000005311.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 57.7658 bits (138), Expect = 1.984e-9 Identity = 28/91 (30.77%), Postives = 47/91 (51.65%), Query Frame = 2 Query: 710 LQMNQMDKIQARQELNKIFLSIFSE-----KINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 +Q+ M A Q +F+ + E K NWGR+VA+ F C L A + D+I + +V ++ E++ +WI + GGWEG+ + Sbjct: 74 VQLQSMINDSALQPTQDVFVKVACEIFSDGKFNWGRVVALFYFACRLVIKAVLTKLPDIIRTIINWTVDYLREHVINWIREQGGWEGIRSY 164
BLAST of bax-1 vs. Ensembl Cavefish
Match: zgc:153993 (apoptosis regulator BAX-like [Source:NCBI gene;Acc:103047816]) HSP 1 Score: 51.6026 bits (122), Expect = 2.865e-7 Identity = 21/65 (32.31%), Postives = 41/65 (63.08%), Query Frame = 2 Query: 770 SIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLME 964 +IF++ INWGRIVA+ +L +A + ++I+ + + ++ +++ +WI Q GGWEG++ Sbjct: 113 TIFTDGINWGRIVALFHLAYQLIYNALTQNHLEIIKNIISWVLQYIRQHVSAWIRQQGGWEGVIR 177
BLAST of bax-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008674.1 (pep scaffold:Pmarinus_7.0:GL477107:593792:611133:1 gene:ENSPMAG00000007850.1 transcript:ENSPMAT00000008674.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.5286 bits (127), Expect = 2.882e-9 Identity = 23/76 (30.26%), Postives = 43/76 (56.58%), Query Frame = 2 Query: 743 RQELNKIFLSIFSE-KINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEF 967 R+ ++ + IF++ NWGR+VA+ F L A+ D+++ + +V F+ E++ WI + GGWEG+ + Sbjct: 13 RELFMRVAIQIFADGTFNWGRVVALFYFAYRLVMKAYSRQLLDIVKTIISWAVDFIREHVIQWIREQGGWEGVRTY 88
BLAST of bax-1 vs. Ensembl Nematostella
Match: EDO33714 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRF5]) HSP 1 Score: 47.7506 bits (112), Expect = 3.929e-7 Identity = 25/73 (34.25%), Postives = 36/73 (49.32%), Query Frame = 2 Query: 740 ARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGL 958 AR + IF INWGRIVA+ F ++ R +++ V SF+ + L SWI ++GGW L Sbjct: 30 ARSTFFSVAKEIFQTGINWGRIVALFTFGGVVAHHFIESERPEMVPHVVEWIPSFIADNLLSWIMENGGWVSL 102
BLAST of bax-1 vs. Ensembl Nematostella
Match: EDO47196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN20]) HSP 1 Score: 46.2098 bits (108), Expect = 1.494e-6 Identity = 21/79 (26.58%), Postives = 42/79 (53.16%), Query Frame = 2 Query: 731 KIQARQEL--NKIFLS----IFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGW 949 KI+ R E+ +F + +F + ++W +++A+ F +S M R +L++ + ++V ++L WI HGGW Sbjct: 24 KIRLRSEVIVGDVFRTFGRELFRDGVSWAKVIALFAFAASMSEDCVMQGRPELVKSILNNVRAYVRDHLAVWIRNHGGW 102
BLAST of bax-1 vs. Ensembl Nematostella
Match: EDO42793 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0T4]) HSP 1 Score: 46.2098 bits (108), Expect = 1.631e-6 Identity = 27/67 (40.30%), Postives = 38/67 (56.72%), Query Frame = 2 Query: 761 IFLSIFSEK-INWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGL 958 + L IF + INWGRIV + F +L+ ++++ LI+ + V FV E L WIFQ GGW L Sbjct: 39 VALQIFQDGVINWGRIVTLFYFGYKLALK--VLNQIPLIKMIIEWVVKFVKEKLVKWIFQQGGWVSL 103
BLAST of bax-1 vs. Ensembl Medaka
Match: baxa (apoptosis regulator BAX [Source:NCBI gene;Acc:101168213]) HSP 1 Score: 55.0694 bits (131), Expect = 1.535e-8 Identity = 23/68 (33.82%), Postives = 40/68 (58.82%), Query Frame = 2 Query: 758 KIFLSIFSEKI-NWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGL 958 K+ L IFS+ + NWGR+V + F C L A + D+I ++ ++ +Y+ +WI + GGW+G+ Sbjct: 95 KVALEIFSDGVYNWGRVVTLFYFACRLVIKALITKVPDIIRTIFTWTIDYLRDYVIAWIREQGGWDGI 162
BLAST of bax-1 vs. Ensembl Medaka
Match: zgc:153993 (apoptosis regulator BAX [Source:NCBI gene;Acc:101168687]) HSP 1 Score: 51.6026 bits (122), Expect = 6.448e-7 Identity = 30/107 (28.04%), Postives = 51/107 (47.66%), Query Frame = 2 Query: 650 IKYFEEKFNSDSSDWLRTNALQ--MNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLME 964 IK E+ + D R LQ +NQ A+ ++ SIF++ INWGR+VA+ + A + + I + + + E L+ W+ Q GGW G+++ Sbjct: 160 IKEVVEQLLKIADDINRNAVLQQLINQASGSGAQDIFMEVARSIFADGINWGRVVALFHLAYKFIYKALTSNHLETIRMIISWVLQVIKEVLYPWLVQQGGWVGVIQ 266
BLAST of bax-1 vs. Ensembl Medaka
Match: ENSORLT00000046675.1 (bcl-2-like protein 1 [Source:NCBI gene;Acc:101165300]) HSP 1 Score: 48.1358 bits (113), Expect = 6.201e-6 Identity = 31/123 (25.20%), Postives = 55/123 (44.72%), Query Frame = 2 Query: 620 DKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGWEGLMEFQTGQSGS 988 D +L+ FE +F+ SD ++Q++ + A Q ++ +F + INWGR+V + F L + +L+ ++DE + WI HGGW+ GQ+G+ Sbjct: 67 DAIKSTLKDSADEFERRFHQGFSDL----SVQLH-ITPDTAYQNFKRVLDELFKDGINWGRVVGLFVFGGALCVECVERNMGELVSRIAEWMTQYLDEQISPWIHSHGGWDCFARL-YGQNGA 183
BLAST of bax-1 vs. Planmine SMEST
Match: SMESG000037989.1 (SMESG000037989.1) HSP 1 Score: 565.844 bits (1457), Expect = 0.000e+0 Identity = 286/288 (99.31%), Postives = 288/288 (100.00%), Query Frame = 2 Query: 86 MGDYDTDDELKNDAHFDDSIPSMESESICDRITNNSSNATPVNNGDDYXXXXXXXXXXXXXXCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGW 949 MGDY+TDDELKNDAHFDDSIPSME+ESICDRITNNSSNATPVNNGDDYSSSNSHRNHRHNPRCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGW Sbjct: 1 MGDYNTDDELKNDAHFDDSIPSMEAESICDRITNNSSNATPVNNGDDYSSSNSHRNHRHNPRCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEKINWGRIVAMIGFVCELSSSAFMIHRHDLIEEYVYTSVSFVDEYLWSWIFQHGGW 288
BLAST of bax-1 vs. Planmine SMEST
Match: SMESG000037406.1 (SMESG000037406.1) HSP 1 Score: 449.514 bits (1155), Expect = 8.413e-159 Identity = 233/234 (99.57%), Postives = 234/234 (100.00%), Query Frame = 2 Query: 86 MGDYDTDDELKNDAHFDDSIPSMESESICDRITNNSSNATPVNNGDDYXXXXXXXXXXXXXXCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEK 787 MGDYDTDDELKNDAHFDDSIPSME+ESICDRITNNSSNATPVNNGDDYSSSNSHRNHRHNPRCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEK Sbjct: 1 MGDYDTDDELKNDAHFDDSIPSMEAESICDRITNNSSNATPVNNGDDYSSSNSHRNHRHNPRCYTAEVFVKGISYVLKKKIKNCSPSNIPTERKYVNLLSVDDGFQEDNPSPLMSSICSDRDQGALSDASSEGFYCQNDYNHACNEGLCMHVTPFISKLKQNFFLPNNDQCALLPKFDDKFYKSLEHLIKYFEEKFNSDSSDWLRTNALQMNQMDKIQARQELNKIFLSIFSEK 234 The following BLAST results are available for this feature:
BLAST of bax-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 4
BLAST of bax-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of bax-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of bax-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of bax-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 2
BLAST of bax-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 2
BLAST of bax-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 1
BLAST of bax-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of bax-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of bax-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of bax-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of bax-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of bax-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of bax-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015261 ID=SMED30015261|Name=bax-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1393bpback to top protein sequence of SMED30015261-orf-1 >SMED30015261-orf-1 ID=SMED30015261-orf-1|Name=SMED30015261-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=337bp MGDYDTDDELKNDAHFDDSIPSMESESICDRITNNSSNATPVNNGDDYSSback to top Annotated Terms
The following terms have been associated with this transcript:
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