Netrin-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015232 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Netrin-1 vs. Ensembl Human
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]) HSP 1 Score: 390.578 bits (1002), Expect = 1.130e-125 Identity = 224/613 (36.54%), Postives = 334/613 (54.49%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI-----PSSGMADMANTSPVCK---KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+Q PC NG P++C+P F N +STCG P + C + E + C +C+A +++PP+ +TD + P N TCW S + P + V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + + P + IT N E +C + R G ++ FST+ GRPS + S L +W+T TD+R++ R F E L Y + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P + A C K ++ + +I KK+C++ + L + G+ ++ + I ++ K + R ++ WI S D+ C CPK++ + YL+L A+ + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKADKAGDWWKFTVNIISVY---KQGTSRIRRGDQSL-----WIRSRDIACKCPKIKPLKKYLLLGNAED--SPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. Ensembl Human
Match: NTN3 (netrin 3 [Source:HGNC Symbol;Acc:HGNC:8030]) HSP 1 Score: 307.375 bits (786), Expect = 2.876e-94 Identity = 196/613 (31.97%), Postives = 291/613 (47.47%), Query Frame = 2
Query: 56 ILNLSVWIHSVKVIFESQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAF-KMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKK-----CNEKRK--RIVFKKFCRRK-SVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSY---LILTRAKYYLYLRNKELYIDSR-SVMLPWHNSW 1840
+L ++ + + PC+ G P+ C+P N + +STCG R CDA R++ P+ +T + CW S L P V +TV L K+FE+ +++L+ C P S+A+ KS D G SW P FFS C + ++P + P E LC AP D +L FS P G S L +W+T TD+R+ L R + P ++ + ++ + +DL VGGRCKCNGHA+RCL+D + CDC H TEG +C RCK Y DRPWQRAT + ++ C C CN H+ RC FN ++Y + +GGVC+NCRH+T G +C C GF+R+ + R AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC G++QS S V PC+ + ++SPV + C R RI KKFC++ +V A E G R+ + + ++R + E R + A+ W+ + D C CP++ G+ Y A I +R S++LPW ++W
Sbjct: 9 LLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCG-------------------RPATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAP--LNVTLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGP----EALC--FPAPLAQPD---GSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPS-TAGDPRDMEAVVPYS--------------------YAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKT-CNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSHCKPARGSYRISLKKFCKKDYAVQVAVGARGEARGAWTRFPVAVLAVFRSGE---ERARRGSSAL-----WVPAGDAACGCPRLLPGRRYLLLGGGPGAAAGGAGGRGPGLIAARGSLVLPWRDAW 561
BLAST of Netrin-1 vs. Ensembl Human
Match: LAMC1 (laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492]) HSP 1 Score: 234.187 bits (596), Expect = 1.043e-63 Identity = 152/446 (34.08%), Postives = 226/446 (50.67%), Query Frame = 2
Query: 128 NGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPG-QNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQ-SNSTVRPC 1432
GRPQ+C+P F N NV T+TCGT PE+ C + C +CDA H + + +TD + + T W S + + +N+T+ L K+F++ Y+ L+ + P+S AIYK W P+Q++S C + + T + + LC + ++D + FST+ GRPS + L EW+T TD+R++L R F E + P LK YY +SD AVGGRCKCNGHA+ C+ ++ D++ C+C HNT G +CE+C + DRPW+RAT ++A+ C CDCN S CYF+ ++Y + GG C NC+ +T G +CE C FFR + AC+SC C +GS+ +CD G+C C+ GV G CDRC+ G+ + + RPC
Sbjct: 44 GGRPQRCMPEFVNAAFNVTVVATNTCGTP-PEEYC---VQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKAN---RGFIRTGGDEQQALCTD-----EFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYY-----------------------AISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGH--GGHCTNCQDNTDGAHCERCRENFFRLG-----NNEACSSCHCSPVGSLS-TQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPC 445 HSP 2 Score: 76.2554 bits (186), Expect = 2.171e-13 Identity = 51/134 (38.06%), Postives = 67/134 (50.00%), Query Frame = 2
Query: 992 CHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCK 1393
C +NT G C+RCK + P A+ CK C+CNL+ Q N T G C C H TG +C C+ GF+ N Q C C CH +GS +CD +TGQC C+ G+TGQ C+RC+
Sbjct: 852 CIYNTAGFYCDRCKDGFFGNPL---APNPADKCKACNCNLYGTM----KQQSSCNPVT--GQC-ECLPHVTGQDCGACDPGFY-NLQSGQ----GCERCDCHALGSTN-GQCDIRTGQCECQPGITGQHCERCE 969 HSP 3 Score: 72.0182 bits (175), Expect = 4.306e-12 Identity = 50/160 (31.25%), Postives = 74/160 (46.25%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKC-DCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQ-NECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
C C G ++ ++ E+ C +C T G+ CE C Y P R +C+ C C+ + V N G C+ C ++T G C+ C++GFF N P C +C C+ G++KQ + C+ TGQC C VTGQ C C G+
Sbjct: 773 CPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGR--NGPVRLCRLCQCSDNI------DPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADK-CKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGF 923 HSP 4 Score: 67.781 bits (164), Expect = 6.776e-11 Identity = 68/252 (26.98%), Postives = 98/252 (38.89%), Query Frame = 2
Query: 704 RPSGPPWS-QDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFG-LSDLAVGG---------------RCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKC-HTIGSIKQNECDKKTGQCY-CRDGVTGQTCDRCKDGY 1402
RP+ P+ Q L+ +T +R + E+S Y P P V T P+ + G ++ + G C CNGH+ C D + C+C NT G CE+C Y + +T ++ C+ C C S V VC NC TTG CE C++G+F + C C+C I C++ TG+C C G CDRCKDG+
Sbjct: 636 RPALTPFEFQKLLNNLTSIKIRGTY----SERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETC---DPETGVCNCRDNTAGPHCEKCSDGY----YGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEV--------VCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868
BLAST of Netrin-1 vs. Ensembl Human
Match: LAMC3 (laminin subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:6494]) HSP 1 Score: 223.787 bits (569), Expect = 3.078e-60 Identity = 152/444 (34.23%), Postives = 223/444 (50.23%), Query Frame = 2
Query: 131 GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ--NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEV-LCVELKAPERYNDYGQ-AETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQ-SNSTVRPCI 1435
GRPQ+CLP F N A+ + TCG+ PE C + A A +C CDA R + S++TD H ++++ W+ P Q VNIT+ L K++E+ Y+ L+ + P+S AIYK W+P+QF+S C + + P + + P V C ++D + + FST+ GRPS + S L EW+T T+L ISL R L + + + P L ++ ++ +SD +VGGRCKCNGHA+ C D ++ C C HNT G +CERC + DRPW R T + A+ C C+C+ S C F+ +++ + GG C +CR HT G +CE C+ F+ +W + R C C C + GS+ +CD TG C C+ VTG CDRC G+ S RPC
Sbjct: 30 GRPQRCLPVFENAAFGRLAQASHTCGSP-PEDFCPHV---GAAGAGAHCQRCDAADPQRHHNASYLTDFHS-QDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRP----EGQYLRPGEDERVAFCTS-----EFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDR-------------LNTFGDDIFKDPKVLQSY------YYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH--GGRCHHCRDHTAGPHCERCQENFY-HW----DPRMPCQPCDCQSAGSL-HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCT 431 HSP 2 Score: 79.7221 bits (195), Expect = 1.527e-14 Identity = 59/167 (35.33%), Postives = 80/167 (47.90%), Query Frame = 2
Query: 926 RCKCNGHANRCLIDDNDEIKCD--------CHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
+C+C+G+ +D N CD C HNT G CE C+ + + A+ C C C+ S+ + T G C +C H T +C C GFF Q R C SCKCH +GS ++++C KTGQC CR GVTGQ CDRC+ G+
Sbjct: 809 QCQCSGN-----VDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSAL---APRPADKCMPCSCHPQGS----VSEQMPCDPVT--GQC-SCLPHVTARDCSRCYPGFF----DLQPGRG-CRSCKCHPLGS-QEDQCHPKTGQCTCRPGVTGQACDRCQLGF 954 HSP 3 Score: 76.2554 bits (186), Expect = 1.853e-13 Identity = 59/204 (28.92%), Postives = 78/204 (38.24%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRAT------------------RQNANVCKYCDCNLHSYRC------YFNSQI---------------------YVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSI-KQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
C CN H D N I C C H+TEG CERC + P+ VC +C RC +F + V N G C+ C H+TTG++CE+C+ GF+ + P+ C C CH GS+ +Q CD TGQC C VT + C RC G+
Sbjct: 707 CTCNQHGT---CDPNTGI-CVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPAD-KCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
BLAST of Netrin-1 vs. Ensembl Human
Match: LAMA5 (laminin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6485]) HSP 1 Score: 204.527 bits (519), Expect = 8.533e-54 Identity = 134/450 (29.78%), Postives = 211/450 (46.89%), Query Frame = 2
Query: 152 PSFTNIIENVKAETTSTCGTNGPEQ----ICRNWY-----------DKTTAEARQYCSICDA--KHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGT-LPDSIAIYKSLDFGVSWKPWQFFS---QDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDE---IKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVR-------NNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
P + N+ E + ++TCG P + + Y D QYC IC A ++++P S+ D + W S PL NEVN+T+ L + F V Y+ ++ + PD + +S+DFG +++PWQFF+ +DC F P T E+ ++ A +C + R E V+ S + GRP +S L E+ T++R+ +R L H P + ++ + D+++GGRC C+GHA+ C D + ++C C HNT G C+RC + +PW+ AT +AN C+ C+C H+ CY++ ++ R Y GGVCI+C+HHTTG NCE C GF+R+ P + C C C + C+ TG+CYCR +G+ CD C +G+
Sbjct: 47 PPYFNLAEGARIAASATCGEEAPARGSPRPTEDLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASNAID----GTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASSKRDCLERFG-PQTLERITRDDAA-----ICTTEYS--RIVPLENGEIVV--SLVNGRPGAMNFSYSPLLREFTKATNVRLRFLR----------TNTLLGHLMGKALRDPTVTRR-----YYYSIKDISIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCES--DFTDGTCEDLTGRCYCRPNFSGERCDVCAEGF 465 HSP 2 Score: 91.6633 bits (226), Expect = 4.559e-18 Identity = 70/254 (27.56%), Postives = 95/254 (37.40%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANV-CKYCDCNLHSYRCYFNSQIYVRNNYT--------------------------------------NG-------------GVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNST--VRPCI-----------PSSGMADM--ANTSPVCKKC 1489
C+C+GH++RCL + DC HNTEG CERC++ ++ ++R + + C C C L F +R T NG G C C HTTG CE C GF+ N P CT C C G+ CD +G C C+ GVTG+ CDRC++G+ + RPC P SG P C++C
Sbjct: 1864 CQCHGHSDRCL--PGSGVCVDCQHNTEGAHCERCQAGFV------SSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLP----GNCTRCDCTPCGT---EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCREC 2102 HSP 3 Score: 70.8626 bits (172), Expect = 9.467e-12 Identity = 47/159 (29.56%), Postives = 69/159 (43.40%), Query Frame = 2
Query: 986 CDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNE----CDKKTG--QCYCRDGVTGQTCDRCKDGYKQS----NSTVRPC 1432
C C + G C+ C + ++ C C C+ HS RC S GVC++C+H+T G +CE C+ GF + P A C SC C S+ N C + G QC C+ G G +C+RC G+ + S+ +PC
Sbjct: 1831 CLCPASYRGDSCQECAPGF----YRDVKGLFLGRCVPCQCHGHSDRCLPGS-----------GVCVDCQHNTEGAHCERCQAGFVSSRDDPS---APCVSCPCPL--SVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPC 1969 HSP 4 Score: 66.2402 bits (160), Expect = 2.415e-10 Identity = 47/172 (27.33%), Postives = 69/172 (40.12%), Query Frame = 2
Query: 926 RCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKY----------CDCNLHSYR---CYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
RC C +D +C C N G+ C+ C + P T ++N + CDC+ + C + ++ G C+ C+ + G +CE C GF+ C C+C + G + + CD TGQC CR G G TCDRC GY
Sbjct: 428 RCNCESDFTDGTCEDLTG-RCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRV---------GRCL-CKPNFQGTHCELCAPGFYG---------PGCQPCQCSSPG-VADDRCDPDTGQCRCRVGFEGATCDRCAPGY 578 HSP 5 Score: 66.2402 bits (160), Expect = 2.742e-10 Identity = 43/159 (27.04%), Postives = 59/159 (37.11%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQ-NECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
C C+ + D +C C G C+ C + P YC+ C+ V V CR H G +C+ C+ GF W + CT C C G++ EC TGQC+C+ V GQ C CKDG+
Sbjct: 677 CHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFP-------------YCEAG----SCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGF---WGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGF 815 HSP 6 Score: 65.0846 bits (157), Expect = 5.831e-10 Identity = 41/135 (30.37%), Postives = 59/135 (43.70%), Query Frame = 2
Query: 977 EIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTC 1381
++ C C + EG C+RCK + W + N C C C+L + V G C C+ H G C +C++GFF Q C SC+C G++ Q+ C+ +TG C CR G TC
Sbjct: 741 QVPCMCRAHVEGPSCDRCKPGF----WGLSP-SNPEGCTRCSCDLRG------TLGGVAECQPGTGQCF-CKPHVCGQACASCKDGFF---GLDQADYFGCRSCRCDIGGALGQS-CEPRTGVCRCRPNTQGPTC 859 HSP 7 Score: 63.1586 bits (152), Expect = 2.483e-9 Identity = 44/168 (26.19%), Postives = 62/168 (36.90%), Query Frame = 2
Query: 983 KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCD----------------CNLHSYRCY-------------FNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDG 1399
+C CH + G++C RC + Y P R A +C C ++ C+ ++ T+ G C CR + TG C+ C GF C C CH G+ CD TGQCYC++ V G CD+C G
Sbjct: 1456 QCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGF--------HGYPRCRPCDCHEAGT-APGVCDPLTGQCYCKENVQGPKCDQCSLG 1613 HSP 8 Score: 55.4546 bits (132), Expect = 4.540e-7 Identity = 51/193 (26.42%), Postives = 73/193 (37.82%), Query Frame = 2
Query: 929 CKCNGHA---NRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGF--FRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCN 1492
C+C+ +RC D D +C C EG C+RC Y P +C+ C C+ + G C+ C+ G +C+ C G+ F N C +C C G++ Q C G C CR G TG C C G+ S V PC S+ + A P +C+
Sbjct: 541 CQCSSPGVADDRC---DPDTGQCRCRVGFEGATCDRCAPGYFHFP----------LCQLCGCSPAGT---------LPEGCDEAGRCL-CQPEFAGPHCDRCRPGYHGFPN----------CQACTCDPRGALDQ-LCGAG-GLCRCRPGYTGTACQECSPGFHGFPSCV-PCHCSAEGSLHAACDPRSGQCS 697 HSP 9 Score: 53.5286 bits (127), Expect = 2.137e-6 Identity = 40/163 (24.54%), Postives = 59/163 (36.20%), Query Frame = 2
Query: 923 GRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCN--LHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYK 1405
G C+ H+ CL C G+ C+RC+ + C+ C C C+ S G C +CR T G C C G+ W P++ C C+C CD TG+C C G++G+ CD C ++
Sbjct: 2029 GTEACDPHSGHCL----------CKAGVTGRRCDRCQEGHFGF-------DGCGGCRPCACGPAAEGSECHPQS-----------GQC-HCRPGTMGPQCRECAPGY---WGLPEQ---GCRRCQC------PGGRCDPHTGRCNCPPGLSGERCDTCSQQHQ 2150 HSP 10 Score: 53.5286 bits (127), Expect = 2.210e-6 Identity = 46/192 (23.96%), Postives = 68/192 (35.42%), Query Frame = 2
Query: 920 GGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCN---LHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQ-SNSTVRPCIPSSGMADMANTSPVCK 1483
G C+ + RCL C N +G CE C + C+ C C+ + RC ++ G C CR G C+ C G+F H C C C G++ + CD+ G+C C+ G CDRC+ GY N C P + + +C+
Sbjct: 503 GNACRKDPRVGRCL----------CKPNFQGTHCELCAPGFY-----------GPGCQPCQCSSPGVADDRCDPDT-----------GQC-RCRVGFEGATCDRCAPGYF--------HFPLCQLCGCSPAGTLPEG-CDE-AGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCR 651
BLAST of Netrin-1 vs. Ensembl Celegans
Match: unc-6 (Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34710]) HSP 1 Score: 391.349 bits (1004), Expect = 2.615e-126 Identity = 218/605 (36.03%), Postives = 337/605 (55.70%), Query Frame = 2
Query: 116 PCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCV--ELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTS-----PVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
PC+ + GRP +C+P F N + TCGTN P++ C + R+ C CDA++ +S+P S +TD + N TCW S P + V++T+SL K FE+ Y+++ C LPDS+A+YKS DFG +W P+QF+S +C R F + + IT +N E +C + P G PF + RPS + S L +W+T TD+++ R +P+++ ELY + + + N + + + + + +LAVGGRCKCNGHA+RC+ D CDC HNT G ECE CK + DRPW RAT +AN C C+CN H+ RC F+++++ + +GGVC+NCRH+T G NC C+ GF R+ + P HR AC SC CH +GS+ ++ C++ +GQC C+ GVTG TC+RC GY+QS STV PCI AD +S C KC KR+ KKFC+R + +S+E+ +Y++ ++ ++ K E + R ++ WI+ + V C CPK+ +G+ YL+L K L ++ ++V++ W + ++ +F K++K G+C +
Sbjct: 36 PCHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYC-TVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVSTP---SLSPQNVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFG----RDPDVSITKSNEQEAVCTASHIMGP------GGNRVAFPF--LENRPSAQNFENSPVLQDWVTATDIKVVFSRLSPDQA------ELYGLSNDV-NSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKACKSCGCHPVGSLGKS-CNQSSGQCVCKPGVTGTTCNRCAKGYQQSRSTVTPCIKIPTKADFIGSSHSEEQDQCSKCRIVPKRLNQKKFCKRDHAVQMVVVSREMVDGWAKYKIVVESVF---KRGTENMQRGETSL-----WISPQGVICKCPKLRVGRRYLLL--GKNDSDHERDGLMVNPQTVLVEWEDDIMDKVLRFSKKDKLGQCPE 606
BLAST of Netrin-1 vs. Ensembl Celegans
Match: unc-6 (Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34710]) HSP 1 Score: 391.349 bits (1004), Expect = 2.615e-126 Identity = 218/605 (36.03%), Postives = 337/605 (55.70%), Query Frame = 2
Query: 116 PCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCV--ELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTS-----PVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
PC+ + GRP +C+P F N + TCGTN P++ C + R+ C CDA++ +S+P S +TD + N TCW S P + V++T+SL K FE+ Y+++ C LPDS+A+YKS DFG +W P+QF+S +C R F + + IT +N E +C + P G PF + RPS + S L +W+T TD+++ R +P+++ ELY + + + N + + + + + +LAVGGRCKCNGHA+RC+ D CDC HNT G ECE CK + DRPW RAT +AN C C+CN H+ RC F+++++ + +GGVC+NCRH+T G NC C+ GF R+ + P HR AC SC CH +GS+ ++ C++ +GQC C+ GVTG TC+RC GY+QS STV PCI AD +S C KC KR+ KKFC+R + +S+E+ +Y++ ++ ++ K E + R ++ WI+ + V C CPK+ +G+ YL+L K L ++ ++V++ W + ++ +F K++K G+C +
Sbjct: 36 PCHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYC-TVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVSTP---SLSPQNVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFG----RDPDVSITKSNEQEAVCTASHIMGP------GGNRVAFPF--LENRPSAQNFENSPVLQDWVTATDIKVVFSRLSPDQA------ELYGLSNDV-NSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKACKSCGCHPVGSLGKS-CNQSSGQCVCKPGVTGTTCNRCAKGYQQSRSTVTPCIKIPTKADFIGSSHSEEQDQCSKCRIVPKRLNQKKFCKRDHAVQMVVVSREMVDGWAKYKIVVESVF---KRGTENMQRGETSL-----WISPQGVICKCPKLRVGRRYLLL--GKNDSDHERDGLMVNPQTVLVEWEDDIMDKVLRFSKKDKLGQCPE 606
BLAST of Netrin-1 vs. Ensembl Celegans
Match: lam-2 (Laminin-like protein lam-2 [Source:UniProtKB/Swiss-Prot;Acc:Q18823]) HSP 1 Score: 247.284 bits (630), Expect = 1.713e-68 Identity = 156/453 (34.44%), Postives = 230/453 (50.77%), Query Frame = 2
Query: 98 FESQSSPCYLNG--RPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHR--SYPPSHITDRHIPKNQTCWFSGPLQENPGQN---EVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCL----IDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
F + +PCY +PQ+C+P F N N++ + T+TCGT P + C R C CD +H S+P ++TD ++ N+T W S +QE GQ N+T+ L KSF++ Y+ L+ P+S IYK W+PWQF+S C + + + I P N C + ++D + FST+ GRPS + S+ L +W+T + +RISL R F E P L+ YY +SD AVGGRCKCNGHA+ C+ +D + + C C HNT+G +C C Y DRPW+ T AN C C+C+ S RCYF+ Q++ + GG CI+C+ +T G +CE C +W +P E+ C +C C+ IGS+ +CD + G+C C+ GVTG+ CD+C DG+
Sbjct: 33 FGADGNPCYDRATRQPQRCVPDFVNAAFNLEVQVTNTCGTKRPTKFC---VQSGHTGQRSVCETCDDRHEGFSHPAKYLTDFNVGNNETWWQSDTMQE--GQQYPTTTNLTLVLGKSFDITYVRLKFISPRPESFTIYKKTHTDSEWEPWQFYSGSCRATYGLS----DRAPILPGNEATAQCTK-----EFSDISPITGGNIAFSTLEGRPSAHAFEESEVLQKWVTASAIRISLNRMNTFGDEVFKDPQVLRSYYY-----------------------AISDFAVGGRCKCNGHASECVGSSSVDGENRLVCRCEHNTQGADCNECLPFYNDRPWRSGTSVEANECIACNCSQLSNRCYFDQQLFEETGH--GGHCIDCQGNTQGVHCEQC---IANHWRRPGENY--CVACGCNEIGSLS-TQCDNE-GKCQCKPGVTGRFCDQCLDGF 439 HSP 2 Score: 75.8702 bits (185), Expect = 8.656e-14 Identity = 81/282 (28.72%), Postives = 114/282 (40.43%), Query Frame = 2
Query: 926 RCKCNGHANRCLIDDNDEIKCDCHH---NTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKD-GYKQSNSTVRPC----IPSSGMADMANTSPV----------CKKCNEKRKRIV---------FKKFCRRKSVFRATALS-----KEIHG-----NMIRYELKIDEIWRVDKNVWEFLPRET 1660
C C+G+ + I + D+I +C NT G CE CK Y W A + C+ C C R N + N +G +C + G C+ C +GF+ N T C C C +GS + N CD TGQC C+ GVTGQ CDRC D + S + +PC I S N+ C +C E R I + R +VFR S +EI N +++ K+ E R VWE + ++T
Sbjct: 834 ECACSGNTDPNSIGNCDKITGECKKCIFNTHGFNCENCKPGY----WGDALIEPKGNCQSCGCFAAGTRRPNNDYTLLECNQQDGQC--DCLPNVIGIQCDQCAHGFY-NITSG----LGCQECNCDPLGS-EGNTCDVNTGQCQCKPGVTGQRCDRCADYHFGFSANGCQPCDCEYIGSENQQCDVNSGQCLCKENVEGRRCDQCAENRYGITQGCLPCDDCYTLIQSRVNVFREKVKSLDNTLQEIIENPAPVNDTKFDEKVKETSRAASEVWEAVKQKT 1103 HSP 3 Score: 61.2326 bits (147), Expect = 2.727e-9 Identity = 55/206 (26.70%), Postives = 75/206 (36.41%), Query Frame = 2
Query: 926 RCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNAN------------------VCKYCDCNLHSYRCYFNSQIYVRNNYTN-----------------------GGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQN------ECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
+C C+ H+N C + C C HNT G CERC Y Q T ++ +C C RC S Y N G C C +T G NCENC+ G++ + E + C SC C G+ + N EC+++ GQC C V G CD+C G+
Sbjct: 735 KCDCHNHSNSCEAESG---SCICEHNTAGDTCERCARGYYGDALQ-GTEEDCQKCPCPNDGPCILHADGDVICTECPNGYTGRRCDECSDGYFGNPKDGTECVECACSGNTDPNSIGNCDKITGECKKCIFNTHGFNCENCKPGYWGDALI--EPKGNCQSCGCFAAGTRRPNNDYTLLECNQQDGQCDCLPNVIGIQCDQCAHGF 934 HSP 4 Score: 57.3806 bits (137), Expect = 4.026e-8 Identity = 56/189 (29.63%), Postives = 77/189 (40.74%), Query Frame = 2
Query: 986 CDCHHNTEGQECERCKSNYLDRPWQRATRQNA--NVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKC--------HTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI--PSSGMADMANTSPVCKKCNEKRKRIVF 1516
C+C GQ CE C+S + +R T+ N C CDC+ HS C S G CI C H+T G+ CE C G++ + + E C C C H G + E C +G TG+ CD C DGY + C+ SG D N+ C K + K+ +F
Sbjct: 702 CECLPGFVGQFCESCESGF-----RRETKFGGPFNHCIKCDCHNHSNSCEAES-----------GSCI-CEHNTAGDTCERCARGYYGDALQGTEED--CQKCPCPNDGPCILHADGDVICTE---------CPNGYTGRRCDECSDGYFGNPKDGTECVECACSGNTD-PNSIGNCDKITGECKKCIF 861
BLAST of Netrin-1 vs. Ensembl Celegans
Match: lam-1 (LAMinin related. See also lmb [Source:UniProtKB/TrEMBL;Acc:V6CIX7]) HSP 1 Score: 175.252 bits (443), Expect = 8.406e-45 Identity = 127/455 (27.91%), Postives = 214/455 (47.03%), Query Frame = 2
Query: 146 CLPSFTNIIENVKAE--TTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK------HRSYPPSH-----ITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTE--PIVHFGLSDLAVGGRCKCNGHANRCL-ID------------DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKK--------TGQCYCRDGVTGQTCDRCKDGY 1402
C P N++ K++ TSTCG+ G ++ C + E + C CD++ Y SH +T+ KN+ W+ EN QN V+I+ L+ F ++ + P ++ I +S DFG +W+ +++F+ DC +F P E P +V+C +Y+D P + + + ++ ++ + E ST ++ L ++ L +L++++ E ++ + ++ V G C C GHA+RC+ ID D +C+C HNTEG CE+CK+ Y D PW+ A N C+ C+CN H+ RC+F+ +Y + + +GGVC +C H+T G NCE C+ F+R+ + + C C+C GS + C+ + G+CYC+ V G CDRCK+GY
Sbjct: 37 CYPITGNLLIGRKSQLKATSTCGSQGRQRFCIVSH----LEEQTKCFYCDSRTEWKPQREPYRLSHRIENVVTEVMDDKNRN-WYQ---SENGAQN-VSISFDLEAEFHFTHLIMTFKSFRPAAMIIERSADFGKTWQVYRYFAYDCDSSF--PGIPEG----PPKKHTDVICTS-----QYSDVA------------------PSTGGEIVYKVISPHIVTENPYADEISTLLKITNLRFNFTKLHTLGDDLLDYRPEIDEKYYYAIYEIVVRGSCSCYGHASRCIPIDPHVSPNTVMERADIVHGRCECMHNTEGLNCEKCKAFYNDLPWRPAIGDEKNECRQCNCNRHALRCHFDRAVYESSGFVSGGVCDDCMHNTQGKNCEQCKPFFYRDPRRTIDDPHVCLPCECDKAGSQNKGICEGEEDAERGLVAGKCYCKTNVDGNRCDRCKNGY 453 HSP 2 Score: 72.7886 bits (177), Expect = 8.346e-13 Identity = 52/186 (27.96%), Postives = 84/186 (45.16%), Query Frame = 2
Query: 893 HFGLSDLAVGGRCK---CNG-------HANRCLI----DDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNG-GVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGS-IKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
++G L VG CK C G HA+ C + ++ +I C+C +G+ C C N+ P R+ C+ CDCN N + + + G C+ C HHT G CE+C +G++ + C C C+ +G+ + CD+ +GQC C D + G CD+C + +
Sbjct: 909 YYGDPRLGVGIPCKPCPCPGGPTSGYQHADTCYLRNSGNNTQDIVCNCKSGYQGERCGECAQNHWGSP-----REVGGTCERCDCN-------GNIDMAMEGSCDAATGECLKCLHHTEGAQCEHCVDGYYGDA-----KLKTCQRCVCNELGTNSTKGACDRVSGQCPCHDNIIGMQCDQCAENH 1077 HSP 3 Score: 56.9954 bits (136), Expect = 5.541e-8 Identity = 60/195 (30.77%), Postives = 78/195 (40.00%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANV-CKYCDCNLHSYRCYFNSQI-YVRN--NYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCH-TIGSIKQNECDKKTGQC-------------YCRDGVTG----QTCDRCKDGYKQSNSTVRPCIPSSG 1447
C+CN HAN C D + +C T G C+RC+ Y P R + CK C C Y ++ Y+RN N T VC NC+ G C C +W P+E C C C+ I + CD TG+C +C DG G +TC RC +NST C SG
Sbjct: 874 CQCNDHANIC--DQSSGACIECRDLTTGHYCDRCQDGYYGDP-----RLGVGIPCKPCPCPGGPTSGYQHADTCYLRNSGNNTQDIVC-NCKSGYQGERCGECAQ---NHWGSPREVGGTCERCDCNGNIDMAMEGSCDAATGECLKCLHHTEGAQCEHCVDGYYGDAKLKTCQRCVCNELGTNSTKGACDRVSG 1057 HSP 4 Score: 56.9954 bits (136), Expect = 6.401e-8 Identity = 45/182 (24.73%), Postives = 75/182 (41.21%), Query Frame = 2
Query: 893 HFGLSDLAVGGRCKCNGHANRCLIDDNDEI--KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPC 1432
++G + L RC CN D + +C CH N G +C++C N+ + + C+ C C+ + +++ N +G C+ G C+ CE+ ++ + T P C C+C+ GS K +C + G C C+ G G C+ C GY PC
Sbjct: 1026 YYGDAKLKTCQRCVCNELGTNSTKGACDRVSGQCPCHDNIIGMQCDQCAENHFNLA-------SGAGCEACGCDSNGVVLNHEGVPHLQCNIFDGQC--QCKPGRGGRKCDQCEDLYWGDPTTPD----GCHRCECNPTGS-KSLQCHRNNGTCECQAGSGGALCNECARGYTGQWPYCNPC 1193 HSP 5 Score: 49.6766 bits (117), Expect = 9.150e-6 Identity = 45/160 (28.12%), Postives = 66/160 (41.25%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCK-SNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCY-CRDGVTGQTCDRCKDGY 1402
C C+ + I + +C+C N G+ C++C Y P + CK CDC+ + G C+ G C C+ GF W P+ C +C+C+ +I CD+ +G C CRD TG CDRC+DGY
Sbjct: 779 CNCDATGSVSGICNVQGGQCECKPNVVGRRCDQCAIGTYGFGP---------SGCKKCDCDAVGS--------LGNDCDKQSGQCVCREKGIYGRQCNQCQPGF---WGFPE-----CRTCQCNDHANI----CDQSSGACIECRDLTTGHYCDRCQDGY 909
BLAST of Netrin-1 vs. Ensembl Celegans
Match: lam-3 (LAMinin related. See also lmb; Laminin alpha chain [Source:UniProtKB/TrEMBL;Acc:G5ECE3]) HSP 1 Score: 173.326 bits (438), Expect = 3.995e-44 Identity = 131/455 (28.79%), Postives = 207/455 (45.49%), Query Frame = 2
Query: 149 LPSFTNIIENVKAETTSTCGTNGPEQICR----NWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGT-LPDSIAIYKSLDFGVSWKPWQFFSQ---DCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHF-GLSDLAVGGRCKCNGHANRCLIDD-NDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQ-------IYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSI--------KQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPC 1432
P+ N+ N T TCG E+ C+ KTT C ICDA H+ +P + D + W S L +VNIT+ L++ ++V YI L++ + P + + KSLD G ++PWQ+++ +C R F +P T +H C + + G+ T L + GRP S +E T R +R ++ L + ++SL K+ + +F +SD+++GG+C C GHA C D + KC+C HNT G+ C RC + PW+ T + NVC+ C C H++ C ++ + I Y GG C+ C H+T G NCE C++G++R AC +C+C +GS+ + E +K G C C+ G G+ C+RC GY+ ++ T PC
Sbjct: 49 FPNIFNLATNSLITATDTCGQYTAEEYCKLVEHVLLRKTTNTQSPQCDICDANNVHKRHPIEYAID----GTRRWWQSPSLANGLRFEKVNITIDLRQEYQVAYIILKMGNSPRPGTWVLEKSLD-GEYYEPWQYYAMQDAECMRQFGIPATTGVPRFQKEDEVH---CTSEYSKITPLENGEIHTSL----VNGRPGAENTS---LELQKFTRARFVRLRLISPRTLNADLMIINKKSDSL---------DKSVTMRYFYSISDISIGGQCICYGHAESCPSDPVTGQFKCECRHNTCGESCNRCCPLFNQLPWKPGTNSHPNVCQQCQCFNHAHSCVYDDELDRNKWSITPEGVYEGGGRCLECAHNTEGFNCERCKDGYYRPSGLSHYREDACRTCECDPVGSVSDACVRDDQSAENGQKPGDCICKPGFGGRRCERCAPGYR-NHPTCEPC 478 HSP 2 Score: 84.7297 bits (208), Expect = 1.994e-16 Identity = 57/168 (33.93%), Postives = 81/168 (48.21%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPC 1432
C C+GH+ C D + + DC HNT G CE C Y+ A AN C C C L + +S + V ++ G VC +C+ TG CE C G++ + PQ C+ C CH GS+ C+ +GQC C+ GVTG+TC C++ + N C
Sbjct: 1540 CSCHGHSQTCNPDTS--VCTDCEHNTFGDFCEHCLPGYIGD----AREGGANACTKCACPLVE-NSFSDSCVAV--DHGRGYVCNSCKPGYTGQYCETCVAGYYGD---PQHIGGTCSPCDCHPDGSL-HGACNPLSGQCECKPGVTGRTCSMCQERHAFINRVCTSC 1694 HSP 3 Score: 77.7962 bits (190), Expect = 2.759e-14 Identity = 57/172 (33.14%), Postives = 79/172 (45.93%), Query Frame = 2
Query: 893 HFGLSDLAVGGRCKCN--GHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
H+G + L C C+ G N ++N E C+C N G +C+RCK N+ D N C CDCN Q+ G C NC+ G C+ C +F N+T A C C C+ GSI+ +CD+ TG+C CR+ V G C++C DGY
Sbjct: 929 HWGNAQLHTCKPCGCHTQGAVNPQCSEENGE--CECKENYIGAQCDRCKENHGDV---------ENGCPACDCNDTGSIGSDCDQV--------SGQC-NCKQGVFGKQCDQCRPSYF-NFTD-----AGCQFCHCNIYGSIEDGKCDQTTGKCECRENVEGTMCEKCADGY 1074 HSP 4 Score: 75.485 bits (184), Expect = 1.328e-13 Identity = 80/315 (25.40%), Postives = 123/315 (39.05%), Query Frame = 2
Query: 812 LKELYYHTES-------LPQAPPNLVNHKTEPIV--HFGLSDLAVGGRC-KCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQR---------------------------------ATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYT--------NG--------------GVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCR--RKSVFRAT 1555
LK L YHT+ + + P N + E V + +++ GGRC KC+ H N D +C HNT G CE CK ++ P + A+ ++ VC C +C + S + + T NG G C+ C HTTG++CE+C+ +W Q H C C CHT G++ +C ++ G+C C++ G CDRCK+ + + C + + ++ V +CN K+ VF K C R S F T
Sbjct: 723 LKALAYHTQDTLMGGVEVCECPENFAGNSCESCVPGYRRVNNQLYGGRCEKCDCHGNSEECDPFTGECLNCRHNTTGSRCELCKPGHVGNPSRGGELGACEQCECPSLDLNPNPECISTELAVLGSVASNEDNYVCINCPLGYEGNKCEYCSDGFFEDPLTGKCIECTCNGNIDPMGIGNCDSETGKCLKCIGHTTGDSCESCKE---HHWGNAQLH--TCKPCGCHTQGAVNP-QCSEENGECECKENYIGAQCDRCKENHGDVENGCPACDCNDTGSIGSDCDQVSGQCNCKQG--VFGKQCDQCRPSYFNFT 1029 HSP 5 Score: 60.8474 bits (146), Expect = 3.743e-9 Identity = 53/190 (27.89%), Postives = 84/190 (44.21%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEI--KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY----KQSNSTVRPCIPSSGMADMANTSPVC 1480
C CN + + D D++ +C+C G++C++C+ +Y + + A C++C CN+ + S + + T G CR + G CE C +G+F N T C C C GS + C+ TGQC C+ GVTG CD C + + + PC + D + S VC
Sbjct: 988 CDCNDTGS--IGSDCDQVSGQCNCKQGVFGKQCDQCRPSYFN--FTDAG------CQFCHCNI------YGSIEDGKCDQTTGKC--ECRENVEGTMCEKCADGYF-NITSGD----GCEDCGCDPTGS-EDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEGCTECEPCPAPGQVCDPIDGSCVC 1153
BLAST of Netrin-1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0073942) HSP 1 Score: 356.295 bits (913), Expect = 1.899e-111 Identity = 236/720 (32.78%), Postives = 340/720 (47.22%), Query Frame = 2
Query: 95 IFESQS---SPCYLNG-RPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQIC--GTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFT-PEKSTPYRLK-----ELYYHTESLPQAPPNLVNH----------KTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSS----GMADMANTSP----------------------------------VCKKCNEKRKRIVFKKFCRR------KSVFRAT---ALSKEIH---------------------------------------------GNMIRYELKIDEIWRVDK--------NVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREK 1876
+F Q+ PCY P+ C+P F N + +STCG++G ++ C + + C CD RS+P +TD + N TCW S P+ + G N V +T+SL K FE+ Y+ LQ+C PDS+ IYKS D G+SW+P+QFFS C R F P N HE C ++ P + + FST+ GRPS S L +W+T TD+R+ R P+ L+ +L S+P A N+ + +H+ +SD +VGGRCKCNGHA++C D + ++ C+C HNT G++CERCK + DRPW RAT + AN CK C+CN H+ +C FN +I+ + +GGVC NCRH TTG NC C+ GF+R+ TKP HR C +C CH IGS + C+ +GQC C+DGVTG TC+RC GY+QS S + PCI M D NT+P C KC KR+ KFC+R K + R T A+S+E+ M R++L+I +++ + NV+ +P T I ++D+ C CP++ + +SYLIL R L I S+++ W W RR+++FQ+R +
Sbjct: 29 MFSQQAPPEDPCYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYCE------YQDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGS-GDN-VTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH----NEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGSSGK-ICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIKQPPRMINMLDTQNTAPEPDEPESSPGSGGDRNGAAGMAAQSQYYRTEGGRECGKCRVSTKRLNLNKFCKRDYAIMAKVIGRDTSSEAVSREVQRRAMDPDVADYEMDQVQPGSARSPITGVYEFQAADYPNPNPNPRGSEMERFDLQIQAVFKRSRPGESSGAGNVYG-MPNTTLKRGPMTWIIPTKDLECRCPRIRVNRSYLILGRDS---EAPPGYLGIGPHSIVIEWKEDWYRRMKRFQRRAR 723
BLAST of Netrin-1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0346088) HSP 1 Score: 356.295 bits (913), Expect = 1.899e-111 Identity = 236/720 (32.78%), Postives = 340/720 (47.22%), Query Frame = 2
Query: 95 IFESQS---SPCYLNG-RPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQIC--GTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFT-PEKSTPYRLK-----ELYYHTESLPQAPPNLVNH----------KTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSS----GMADMANTSP----------------------------------VCKKCNEKRKRIVFKKFCRR------KSVFRAT---ALSKEIH---------------------------------------------GNMIRYELKIDEIWRVDK--------NVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREK 1876
+F Q+ PCY P+ C+P F N + +STCG++G ++ C + + C CD RS+P +TD + N TCW S P+ + G N V +T+SL K FE+ Y+ LQ+C PDS+ IYKS D G+SW+P+QFFS C R F P N HE C ++ P + + FST+ GRPS S L +W+T TD+R+ R P+ L+ +L S+P A N+ + +H+ +SD +VGGRCKCNGHA++C D + ++ C+C HNT G++CERCK + DRPW RAT + AN CK C+CN H+ +C FN +I+ + +GGVC NCRH TTG NC C+ GF+R+ TKP HR C +C CH IGS + C+ +GQC C+DGVTG TC+RC GY+QS S + PCI M D NT+P C KC KR+ KFC+R K + R T A+S+E+ M R++L+I +++ + NV+ +P T I ++D+ C CP++ + +SYLIL R L I S+++ W W RR+++FQ+R +
Sbjct: 29 MFSQQAPPEDPCYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYCE------YQDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGS-GDN-VTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH----NEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGSSGK-ICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIKQPPRMINMLDTQNTAPEPDEPESSPGSGGDRNGAAGMAAQSQYYRTEGGRECGKCRVSTKRLNLNKFCKRDYAIMAKVIGRDTSSEAVSREVQRRAMDPDVADYEMDQVQPGSARSPITGVYEFQAADYPNPNPNPRGSEMERFDLQIQAVFKRSRPGESSGAGNVYG-MPNTTLKRGPMTWIIPTKDLECRCPRIRVNRSYLILGRDS---EAPPGYLGIGPHSIVIEWKEDWYRRMKRFQRRAR 723
BLAST of Netrin-1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0308337) HSP 1 Score: 331.643 bits (849), Expect = 8.768e-103 Identity = 192/490 (39.18%), Postives = 266/490 (54.29%), Query Frame = 2
Query: 95 IFESQS---SPCYLNG-RPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQIC--GTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFT-PEKSTPYRLK-----ELYYHTESLPQAPPNLVNH----------KTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSS----GMADMANTSP 1474
+F Q+ PCY P+ C+P F N + +STCG++G ++ C + D + C CD RS+P +TD + N TCW S P+ + G N V +T+SL K FE+ Y+ LQ+C PDS+ IYKS D G+SW+P+QFFS C R F P N HE C ++ P + + FST+ GRPS L +W+T TD+R+ R P+ L+ +L S+P A N+ + +H+ +SD +VGGRCKCNGHA++C D + ++ C+C HNT G++CERCK + DRPW RAT + AN CK C+CN H+ +C FN +I+ + +GGVC NCRH TTG NC C+ GF+R+ TKP HR C +C CH IGS + C+ +GQC C+DGVTG TC+RC GY+QS S + PCI M D NT+P
Sbjct: 29 MFSQQAPPEDPCYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYC-EYQDH-----ERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGS-GDN-VTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH----NEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVCKACDCHPIGSSGK-ICNSTSGQCPCKDGVTGLTCNRCARGYQQSRSHIAPCIKQPPRMINMLDTQNTAP 497
BLAST of Netrin-1 vs. Ensembl Fly
Match: NetB (gene:FBgn0015774 transcript:FBtr0331596) HSP 1 Score: 234.572 bits (597), Expect = 7.162e-66 Identity = 141/410 (34.39%), Postives = 191/410 (46.59%), Query Frame = 2
Query: 878 TEPIV-HFGLSDLAVGGRCKCNGHANRCLI--------------DDNDE-----------------------IKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPV-------------------------CKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYEL----KIDEIWRVDKNVWEFLPRETPAMHTYRAWIN---------SEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKR 1879
T PI H+ +SD AVGGRCKCNGHA+ C+ D DE + C C HNT G ECERCK Y DRPW RAT +AN CK C CN H+ RC FN ++Y + +GGVC NC+H TTG C C G++R+ TKP HR C C CH +GS + C+ +GQC C++GVTG TC+RC GY+Q+ S V PCI A+M C KC K++ KFC A + + I E + +EI++ + N+ R P T + + + + C CPK++L +SYLIL R L I SV+L W + W R+++FQ+R ++
Sbjct: 379 TLPISQHYAVSDFAVGGRCKCNGHASECVATVSSGSGTALSDQDDGQDEDTPSAPSLANHFGRSTQMSAKLTMTCACKHNTAGPECERCKPFYFDRPWGRATDNDANECKMCQCNGHARRCRFNLELYKLSGRVSGGVCYNCQHDTTGRYCHYCREGYYRDATKPPNHRKVCKRCDCHPVGSTGKT-CNHLSGQCPCKEGVTGLTCNRCARGYQQTRSHVAPCIKVPTNANMIQAESAGGGGGGGTGDYKDGGGSQVEEMKKYCGKCKASPKKLNLNKFCMEDYAILAKVIGHDRASQDISTEKFSIERQNEIYKYEINIQTIFKR-NPMSGTTSSLLGRGNMMLLVPRKSIECQCPKIKLNKSYLILGRDS---EAAPGYLAIGPSSVVLEWKDEWSLRMKRFQRRARK 783 HSP 2 Score: 142.51 bits (358), Expect = 1.157e-34 Identity = 80/236 (33.90%), Postives = 121/236 (51.27%), Query Frame = 2
Query: 104 SQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQ-----ENPGQNEVNITVSLKKSFEVYYIALQIC--GTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLV--EWMTMTDLRISLMRF 784
S + PCY G+P++CLPSF N + +S CG PE+ C D E R + + Y P+ +TD + P N TCW SG + ++ + V +T+SL K +E+ YI+L C PDS+AI+KS DFG +W+P+QF+S C + + P ++I+ N E C+ + +D G A F+T+ GRPS LV +W+T TD+R+ R
Sbjct: 21 SSNDPCYFEGKPRKCLPSFVNAAYGNPVQASSVCGAQQPERYCELLRDGNAGECRS------CEQQRYGPAALTDLNNPSNVTCWRSGAVNVPHDPDSAPPDNVTLTLSLGKKYELTYISLSFCPRSPRPDSLAIFKSSDFGQTWQPFQFYSSQCQKFYGRP----DRAKISKFNEQEARCINSQ-----HDTGGAAQRFAFNTLEGRPSANDLDSSLVLQDWVTATDIRVVFHRL 241
BLAST of Netrin-1 vs. Ensembl Fly
Match: NetB (gene:FBgn0015774 transcript:FBtr0304875) HSP 1 Score: 234.958 bits (598), Expect = 7.496e-66 Identity = 141/410 (34.39%), Postives = 191/410 (46.59%), Query Frame = 2
Query: 878 TEPIV-HFGLSDLAVGGRCKCNGHANRCLI--------------DDNDE-----------------------IKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPV-------------------------CKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYEL----KIDEIWRVDKNVWEFLPRETPAMHTYRAWIN---------SEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKR 1879
T PI H+ +SD AVGGRCKCNGHA+ C+ D DE + C C HNT G ECERCK Y DRPW RAT +AN CK C CN H+ RC FN ++Y + +GGVC NC+H TTG C C G++R+ TKP HR C C CH +GS + C+ +GQC C++GVTG TC+RC GY+Q+ S V PCI A+M C KC K++ KFC A + + I E + +EI++ + N+ R P T + + + + C CPK++L +SYLIL R L I SV+L W + W R+++FQ+R ++
Sbjct: 387 TLPISQHYAVSDFAVGGRCKCNGHASECVATVSSGSGTALSDQDDGQDEDTPSAPSLANHFGRSTQMSAKLTMTCACKHNTAGPECERCKPFYFDRPWGRATDNDANECKMCQCNGHARRCRFNLELYKLSGRVSGGVCYNCQHDTTGRYCHYCREGYYRDATKPPNHRKVCKRCDCHPVGSTGKT-CNHLSGQCPCKEGVTGLTCNRCARGYQQTRSHVAPCIKVPTNANMIQAESAGGGGGGGTGDYKDGGGSQVEEMKKYCGKCKASPKKLNLNKFCMEDYAILAKVIGHDRASQDISTEKFSIERQNEIYKYEINIQTIFKR-NPMSGTTSSLLGRGNMMLLVPRKSIECQCPKIKLNKSYLILGRDSEAA---PGYLAIGPSSVVLEWKDEWSLRMKRFQRRARK 791 HSP 2 Score: 142.51 bits (358), Expect = 1.288e-34 Identity = 80/236 (33.90%), Postives = 121/236 (51.27%), Query Frame = 2
Query: 104 SQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQ-----ENPGQNEVNITVSLKKSFEVYYIALQIC--GTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLV--EWMTMTDLRISLMRF 784
S + PCY G+P++CLPSF N + +S CG PE+ C D E R + + Y P+ +TD + P N TCW SG + ++ + V +T+SL K +E+ YI+L C PDS+AI+KS DFG +W+P+QF+S C + + P ++I+ N E C+ + +D G A F+T+ GRPS LV +W+T TD+R+ R
Sbjct: 29 SSNDPCYFEGKPRKCLPSFVNAAYGNPVQASSVCGAQQPERYCELLRDGNAGECRS------CEQQRYGPAALTDLNNPSNVTCWRSGAVNVPHDPDSAPPDNVTLTLSLGKKYELTYISLSFCPRSPRPDSLAIFKSSDFGQTWQPFQFYSSQCQKFYGRP----DRAKISKFNEQEARCINSQ-----HDTGGAAQRFAFNTLEGRPSANDLDSSLVLQDWVTATDIRVVFHRL 249
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn2 (netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2]) HSP 1 Score: 403.29 bits (1035), Expect = 8.536e-131 Identity = 223/609 (36.62%), Postives = 344/609 (56.49%), Query Frame = 2
Query: 110 SSPCYL-NGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------PSSGMA---DMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+ PCY G ++C+P F N + +S CG P + ++ A + C ICDA ++P S++TD + N TCW S LQ +P V +T+SL K FE+ Y++LQ C P+S+AIYKS+D+G +W P+QF+S C R + P + IT N E LC + + Y + ++ FST+ GRPSG + S L +W+T+TD+R+ R ++ P +E +E AP +L P ++ + D VGGRCKCNGHA+RC+ + + ++ C+C HNTEG EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ K HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S V PCI P++ ++ + A+ CK K I KK+C++ + + L E G+ ++ + + ++ K+ + L R + W++ +D+ C CP++ +G+ +LIL + L D S+++ W + W RRL+KFQ++EK+GKC +
Sbjct: 23 TDPCYEETGAARRCIPEFINAAFGQEVSVSSVCGR--PVSRSCSLVERDDRPAVRTCQICDASDPRNAHPASYLTDLNSAHNLTCWQSENLQSSP--LNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGRTWTPYQFYSSQCRRMYNRP----NKAAITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSGKDFDSSPVLQDWVTVTDIRVVFSRPQHTRALPMSGRE----SEDALGAPGSL------PTYYYAVGDFQVGGRCKCNGHASRCVREKDGKLLCECKHNTEGPECDRCKPFHYDRPWQRATGKEANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGKAITHRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVIKPTAVISTTEEPADCDSYCKPLKGNLK-INMKKYCKKDYAVQVSVLDMETVGDWAKFSVSLMSVY---KSRGDPLKR-----GDHMLWVHMKDLACKCPRIHMGKRFLILGSTEGTANPERPGLQADKNSLVIQWRDIWTRRLRKFQRKEKKGKCSK 599
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn2 (netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2]) HSP 1 Score: 402.905 bits (1034), Expect = 1.244e-130 Identity = 229/644 (35.56%), Postives = 356/644 (55.28%), Query Frame = 2
Query: 14 VYRFFVMIFIRTIAILNLSVWIHSVKVIFESQ---SSPCYL-NGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------PSSGMA---DMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
++RF ++ + T+ HS Q + PCY G ++C+P F N + +S CG P + ++ A + C ICDA ++P S++TD + N TCW S LQ +P V +T+SL K FE+ Y++LQ C P+S+AIYKS+D+G +W P+QF+S C R + P + IT N E LC + + Y + ++ FST+ GRPSG + S L +W+T+TD+R+ R ++ P +E +E AP +L P ++ + D VGGRCKCNGHA+RC+ + + ++ C+C HNTEG EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ K HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S V PCI P++ ++ + A+ CK K I KK+C++ + + L E G+ ++ + + ++ K+ + L R + W++ +D+ C CP++ +G+ +LIL + L D S+++ W + W RRL+KFQ++EK+GKC +
Sbjct: 1 MWRFQTLLSMLTV----FQASSHSPNPFSGPQVTPTDPCYEETGAARRCIPEFINAAFGQEVSVSSVCGR--PVSRSCSLVERDDRPAVRTCQICDASDPRNAHPASYLTDLNSAHNLTCWQSENLQSSP--LNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGRTWTPYQFYSSQCRRMYNRP----NKAAITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSGKDFDSSPVLQDWVTVTDIRVVFSRPQHTRALPMSGRE----SEDALGAPGSL------PTYYYAVGDFQVGGRCKCNGHASRCVREKDGKLLCECKHNTEGPECDRCKPFHYDRPWQRATGKEANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGKAITHRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVIKPTAVISTTEEPADCDSYCKPLKGNLK-INMKKYCKKDYAVQVSVLDMETVGDWAKFSVSLMSVY---KSRGDPLKR-----GDHMLWVHMKDLACKCPRIHMGKRFLILGSTEGTANPERPGLQADKNSLVIQWRDIWTRRLRKFQRKEKKGKCSK 608
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn1a (netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169]) HSP 1 Score: 393.275 bits (1009), Expect = 5.566e-127 Identity = 225/645 (34.88%), Postives = 356/645 (55.19%), Query Frame = 2
Query: 29 VMIFIRTIAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI-----PSSGMADMANTSPVCK---KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVW----EFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
++ + +L +V + + +F +Q+SP CY NG P++C+P F N + +STCG P + C + E + C CDA +++PP+++TD + P N TCW S + P QN V +T+SL K FEV Y++LQ C P+S+AI+KS+D+G SW P+Q++S C + + P+ + IT N E +C + + + + ++ FST+ GRPS + S L +W+T TD++++ R F E L Y + +SDL VGGRCKCNGHA+RC+ D + + C+C HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ +KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC +GY+QS S + PCI P + A C+ K ++ + +I KK+C++ + L + G ++ + I +++ ++ +FL W+ ++DV C CPK++ G+ YL+L + + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 8 LVTLVTLCCVLKGTVGGYGMS-MFAAQTSPPDPCYDENGHPRRCIPDFVNAAFGKEVRASSTCGKT-PSRYC--VVTEKGDERHRNCHTCDASDPKKNHPPAYLTDLNNPHNLTCWQSDNYLQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKSWVPFQYYSTQCRKMYNKPS----KATITKQNEQEAICTD----SHTDMHPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASRCVKDRDGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKPISHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCANGYQQSRSPIAPCIKIPIAPPTTTASSTEEPSDCESYCKASKGKLKINMKKYCKKDYAVQVHILKADKAGEWWKFTVNIISVYKQGESRIRRGDQFL------------WVRAKDVACKCPKIKSGKKYLLLGNDED--SPGQSGMVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 602
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn1a (netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169]) HSP 1 Score: 393.275 bits (1009), Expect = 5.566e-127 Identity = 225/645 (34.88%), Postives = 356/645 (55.19%), Query Frame = 2
Query: 29 VMIFIRTIAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI-----PSSGMADMANTSPVCK---KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVW----EFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
++ + +L +V + + +F +Q+SP CY NG P++C+P F N + +STCG P + C + E + C CDA +++PP+++TD + P N TCW S + P QN V +T+SL K FEV Y++LQ C P+S+AI+KS+D+G SW P+Q++S C + + P+ + IT N E +C + + + + ++ FST+ GRPS + S L +W+T TD++++ R F E L Y + +SDL VGGRCKCNGHA+RC+ D + + C+C HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ +KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC +GY+QS S + PCI P + A C+ K ++ + +I KK+C++ + L + G ++ + I +++ ++ +FL W+ ++DV C CPK++ G+ YL+L + + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 8 LVTLVTLCCVLKGTVGGYGMS-MFAAQTSPPDPCYDENGHPRRCIPDFVNAAFGKEVRASSTCGKT-PSRYC--VVTEKGDERHRNCHTCDASDPKKNHPPAYLTDLNNPHNLTCWQSDNYLQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKSWVPFQYYSTQCRKMYNKPS----KATITKQNEQEAICTD----SHTDMHPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASRCVKDRDGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKPISHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCANGYQQSRSPIAPCIKIPIAPPTTTASSTEEPSDCESYCKASKGKLKINMKKYCKKDYAVQVHILKADKAGEWWKFTVNIISVYKQGESRIRRGDQFL------------WVRAKDVACKCPKIKSGKKYLLLGNDED--SPGQSGMVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 602
BLAST of Netrin-1 vs. Ensembl Zebrafish
Match: ntn1b (netrin 1b [Source:ZFIN;Acc:ZDB-GENE-990415-168]) HSP 1 Score: 392.504 bits (1007), Expect = 1.081e-126 Identity = 223/645 (34.57%), Postives = 351/645 (54.42%), Query Frame = 2
Query: 26 FVMIFIRTIAILNLSVWIHSVK-----VIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------PSSGMADMANTSPVCKKCN--EKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKC 1888
+ I + +++++++ + + +F +QSSP CY NG P++C+P F N +STCG+ P + C + E + C+ICDA +++PP+++TD + P N TCW S + P QN V +T+SL K FEV Y++LQ C P+S+AI+KS+D+G +W P+QF+S C + + P+ + IT N E +C + + G ++ FST+ GRPS + S L +W+T TD++++ R F E L Y + +SDL VGGRCKCNGHA++C+ D + C+C HNT G EC+RCK + DRPWQRAT + AN C C CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ +K HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P+S + + C + + ++ KK+C++ + L + G ++ + I ++ K + R + W+ ++DV C CPK++ G+ YL++ + + D S+++PW + W RRL+KFQ+R+KRGKC
Sbjct: 1 MIRILVTCVSMVSITSMVSGARGGYGMSMFAAQSSPPDPCYDENGNPRRCIPDFVNSAFGKDVRVSSTCGSP-PSRYC--VVTEKGEERSRDCNICDATDPKKTHPPAYLTDLNNPHNLTCWQSENYVQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKTWVPFQFYSTQCKKMYNKPS----KAAITKQNEQEAICTDSHTDMQPLTGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFNRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASKCVKDREGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKAISHRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAAPTSSYSSPDGPTDCDSHCKAPKGKMKVTMKKYCKKDFAVQVHVLKGDKAGEWWKFTINIISVY---KQGGHRIRRGDQLL-----WVRAKDVACKCPKIKPGRKYLLMGSDEEEDSRGQSGVVADRGSLLIPWKDLWARRLRKFQQRDKRGKC 602
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: rps16 (ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-5786511]) HSP 1 Score: 383.259 bits (983), Expect = 4.215e-123 Identity = 226/651 (34.72%), Postives = 341/651 (52.38%), Query Frame = 2
Query: 32 MIFIRTIAILNLSVWI-----HSVKVIFESQS------SPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTE------PIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------PSSGMADMANTSPVCKKCNEKRK--RIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVD----KNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKC 1888
M ++R + L L V HS F Q PCY +G P++C+P F N N + + +STCG A ++C D + +SYP S++TD + N TCW S + QN V++T+SL K FEV Y++LQ C P+S+AI+KS+D+G SW P+Q++S C + + P+ + +T N E LC + + E Y G ++ FST+ GRPS S L +W+T TD+R+ R P+L+ +K P ++ + + VGGRCKCNGHA+RC D + CDC HNTEG EC+RCK + DRPWQRAT + AN C C CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ ++ R AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P+ + + + C + +I KK+C++ V + L E+ G+ ++ + I +++ K FL WI+ +D+ C CPK+ L + YL++ ++ L D S+++ W ++W RRL+K Q+REK+GKC
Sbjct: 1 MFYLREMPHLFLLVSFFPMLPHSTSSPFSGQQQQHSIPDPCYDEHGLPRRCVPEFVNAAFNKEVQASSTCGR----------------LATRHCDTTDPR-KSYPASYLTDLNTAGNMTCWRSETFPRHSSQN-VSLTLSLGKKFEVTYVSLQFCSPRPESVAIFKSMDYGKSWVPYQYYSSQCRKVYGKPS----RASVTKQNEQEALCTDGQT-ELYPLTG---GLIAFSTLDGRPSAQDLDNSPVLQDWLTATDIRVFFSR-------------------------PHLLGNKESEASDEGPGFYYSVGEFQVGGRCKCNGHASRCGKDKEARLICDCKHNTEGPECDRCKPFHYDRPWQRATAREANECMACTCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDVSRAITDRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGLTCNRCAKGYQQSRSPIAPCIKIPAVVPTPALTSTEEPADCEQYCKPPKGNYKINLKKYCKKDFVVQVNVLEMEMVGSWAKFTVNILSVYKCRDDRIKRGDNFL------------WIHIKDLSCKCPKILLSRRYLVMGSSEG--PSERPGLTADKNSMVIQWRDAWTRRLRKLQRREKKGKC 585
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: rps16 (ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-5786511]) HSP 1 Score: 371.318 bits (952), Expect = 7.975e-119 Identity = 222/643 (34.53%), Postives = 331/643 (51.48%), Query Frame = 2
Query: 32 MIFIRTIAILNLSVWI-----HSVKVIFESQS------SPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTE------PIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVD----KNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKC 1888
M ++R + L L V HS F Q PCY +G P++C+P F N N + + +STCG A ++C D + +SYP S++TD + N TCW S + QN V++T+SL K FEV Y++LQ C P+S+AI+KS+D+G SW P+Q++S C + + P+ + +T N E LC + + E Y G ++ FST+ GRPS S L +W+T TD+R+ R P+L+ +K P ++ + + VGGRCKCNGHA+RC D + CDC HNTEG EC+RCK + DRPWQRAT + AN C C CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ ++ R AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI + +P E +V + L E+ G+ ++ + I +++ K FL WI+ +D+ C CPK+ L + YL++ ++ L D S+++ W ++W RRL+K Q+REK+GKC
Sbjct: 1 MFYLREMPHLFLLVSFFPMLPHSTSSPFSGQQQQHSIPDPCYDEHGLPRRCVPEFVNAAFNKEVQASSTCGR----------------LATRHCDTTDPR-KSYPASYLTDLNTAGNMTCWRSETFPRHSSQN-VSLTLSLGKKFEVTYVSLQFCSPRPESVAIFKSMDYGKSWVPYQYYSSQCRKVYGKPS----RASVTKQNEQEALCTDGQT-ELYPLTG---GLIAFSTLDGRPSAQDLDNSPVLQDWLTATDIRVFFSR-------------------------PHLLGNKESEASDEGPGFYYSVGEFQVGGRCKCNGHASRCGKDKEARLICDCKHNTEGPECDRCKPFHYDRPWQRATAREANECMACTCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDVSRAITDRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGLTCNRCAKGYQQSRSPIAPCIKIPAVV----PTPALTSTEE-------------PAVVQVNVLEMEMVGSWAKFTVNILSVYKCRDDRIKRGDNFL------------WIHIKDLSCKCPKILLSRRYLVMGSSEG--PSERPGLTADKNSMVIQWRDAWTRRLRKLQRREKKGKC 560
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: ntn1 (netrin 1 [Source:NCBI gene;Acc:779839]) HSP 1 Score: 367.081 bits (941), Expect = 8.652e-117 Identity = 221/612 (36.11%), Postives = 323/612 (52.78%), Query Frame = 2
Query: 113 SPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGP--PWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------------PSSGMADMANT--SPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRA-WINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKC 1888
PCY RP+ C+P F N+ + T++TCG P+++C + D T +R+ C +CD K SYPPS++TD QTCW S P V +T+ L + FE+ Y +L+ C PDS+AIYKS+D+G +W P+QF+S C R + TT S I+ HE C + + + G ++ F + GRPS +S L +W+T TD+R+ R K R K +Y G+S++ VGGRCKCNGHA+RC + + C+C HNT G EC+ CK Y DRPWQRAT NA+ C C+CNLHS+RC FN ++Y + +GGVC+NCRH+T G +C C+ G+ R+ +KP R AC C+CH IG++ C++ TGQC C+ GVTG TC+RC GY+QS S PC+ P A T CK + R + +K+C++ V RA LS E G ++ + ++R R P + W+ D+ C+C +V++G+SYLI+ + L +D S+ LPW + W +L++FQ++E+RGKC
Sbjct: 40 GPCYDAKQRPKYCIPDFINVALGQEVITSNTCGRT-PQKLC-YFLDSTNVTSRR-CQLCDQKRPENSYPPSYMTDTDA---QTCWKSESGITFP--QNVTLTLPLGRRFELVYASLRFCSPRPDSMAIYKSMDYGKTWIPFQFYSTHCRRVYDQATT----SAISKPMQHEATCTDFQTGVKPLTKG----LVAFMPLAGRPSARRFEYSPVLQDWVTATDIRVVFNRLHHGKKMGIRRKTAFY-----------------------GVSEIQVGGRCKCNGHASRCTAG-KEGLMCECQHNTIGPECDACKPFYYDRPWQRATPSNAHECVACECNLHSHRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKQGYKRDLSKPITSRKACKPCQCHPIGAVNA-MCNQTTGQCQCKTGVTGPTCNRCAPGYQQSRSAHMPCVRIQEEMTTTASYPQEWKAGTNGTECQSYCKP-SHSRVHMNLRKYCKKDYVLRAQLLSMEKSGEWWQFTATVLTVYRQ---------RRVPIRRGDQPLWVPDHDLACDCLRVQVGKSYLIIGNDEE--SPDPARLILDKNSLALPWRDVWGHKLRRFQQQERRGKC 598
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: utp4 (UTP4 small subunit processome component [Source:Xenbase;Acc:XB-GENE-977755]) HSP 1 Score: 227.254 bits (578), Expect = 2.134e-61 Identity = 154/488 (31.56%), Postives = 238/488 (48.77%), Query Frame = 2
Query: 2 EYLHVYRFFVMIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPG-QNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQ-SNSTVRPC 1432
EY+ R + R + L+V + + CY G PQ+C+P F N N T+TCGT PE+ C + C ICD+ H + ++TD + T W S + + +N+T+ L K+F++ Y+ L+ + P+S A+YK W P+Q++S C + ++ + T + + LC + ++D + FST+ GRPS + L EW+T TD+R++L R F E S P LK YY +SD AVGGRCKCNGHA+ C+ ++ ++I C+C HNT G +CE+C Y DRPW+R+T + N C C+CN S CYF+ ++Y + GG C C +T G NCE C ++R Q++ C +C+C+ +GS+ +CD G+C C+ GV G+ CDRC+ G+ + + RPC
Sbjct: 2 EYIGSRRELPALMCRRMRAPVLAVLAVLLLGTVRAAMDECYEEGSPQRCMPEFVNAAFNATVVATNTCGTP-PEEYC---VQTGVTGVTKSCHICDSGQFHLQHGAEYLTDYNNQAEITWWQSQTMLAGIQYPSTINLTLHLGKAFDITYVRLKFHTSRPESFALYKRTHEDGPWIPYQYYSGSCEKTYQKFN---RGFIRTGEDEQQALCTD-----EFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFSDPKVLKSYYY-----------------------AISDFAVGGRCKCNGHASECVRNEFEKIVCNCKHNTFGSDCEKCLPFYNDRPWRRSTADSPNECLPCNCNGRSQECYFDPELYRSTGH--GGHCTGCADNTDGPNCERCRENYYR-----QDNNEPCHACQCNPVGSLS-TQCD-NYGRCSCKPGVMGEKCDRCQPGFHSLTEAGCRPC 445 HSP 2 Score: 78.9518 bits (193), Expect = 2.400e-14 Identity = 56/160 (35.00%), Postives = 76/160 (47.50%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKC-HTIGSIKQNECDKKTGQCY-CRDGVTGQTCDRCKDGY 1402
C CNGH++ C D + CDC HNT G CERC Y + +T +A+ C+ C C S + + R T VC NC TTG CE C++G+F + C C+C + I CD+ TG+C C G CDRC+DG+
Sbjct: 722 CTCNGHSDTC---DPESGVCDCQHNTAGPHCERCSEGY----YGDSTTGSASDCQPCPCPGGS-----SCAVVPR---TKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPCRICECSNNIDPNAVGNCDRLTGECLKCIYNTGGFYCDRCRDGF 866 HSP 3 Score: 63.5438 bits (153), Expect = 1.514e-9 Identity = 48/153 (31.37%), Postives = 67/153 (43.79%), Query Frame = 2
Query: 962 IDDNDEIKCD--------CHHNTEGQECERCKSNYLDRPWQRATRQNANV-CKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCK 1393
ID N CD C +NT G C+RC+ + P QN ++ C+ C CN Y + N G C H T +C CE GF+ + C C CH++GS +CD +TGQC C G++GQ C +C+
Sbjct: 832 IDPNAVGNCDRLTGECLKCIYNTGGFYCDRCRDGFYGNPLA----QNPDLKCRACSCNP-----YGTVKGQSGCNQVTGQC--ECLPHVTERDCSACEPGFYNLLSG-----RGCERCDCHSLGSTS-GQCDVRTGQCECHPGISGQQCQQCE 967 HSP 4 Score: 52.373 bits (124), Expect = 3.409e-6 Identity = 47/153 (30.72%), Postives = 62/153 (40.52%), Query Frame = 2
Query: 986 CDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY----KQSNSTVRPC 1432
C C GQ CERC Y + ++ + C C CN HS C S GVC +C+H+T G +CE C G++ + T + C C C S K+ C G TG+ C+ C DGY N RPC
Sbjct: 688 CSCPTGYIGQFCERCAPGYR---RENPSQGPYSPCVLCTCNGHSDTCDPES-----------GVC-DCQHNTAGPHCERCSEGYYGDSTTGSA--SDCQPCPCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPC 823
BLAST of Netrin-1 vs. Ensembl Xenopus
Match: utp4 (UTP4 small subunit processome component [Source:Xenbase;Acc:XB-GENE-977755]) HSP 1 Score: 225.713 bits (574), Expect = 5.267e-61 Identity = 148/449 (32.96%), Postives = 226/449 (50.33%), Query Frame = 2
Query: 119 CYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPG-QNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQ-SNSTVRPC 1432
CY G PQ+C+P F N N T+TCGT PE+ C + C ICD+ H + ++TD + T W S + + +N+T+ L K+F++ Y+ L+ + P+S A+YK W P+Q++S C + ++ + T + + LC + ++D + FST+ GRPS + L EW+T TD+R++L R F E S P LK YY +SD AVGGRCKCNGHA+ C+ ++ ++I C+C HNT G +CE+C Y DRPW+R+T + N C C+CN S CYF+ ++Y + GG C C +T G NCE C ++R Q++ C +C+C+ +GS+ +CD G+C C+ GV G+ CDRC+ G+ + + RPC
Sbjct: 28 CYEEGSPQRCMPEFVNAAFNATVVATNTCGTP-PEEYC---VQTGVTGVTKSCHICDSGQFHLQHGAEYLTDYNNQAEITWWQSQTMLAGIQYPSTINLTLHLGKAFDITYVRLKFHTSRPESFALYKRTHEDGPWIPYQYYSGSCEKTYQKFN---RGFIRTGEDEQQALCTD-----EFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFSDPKVLKSYYY-----------------------AISDFAVGGRCKCNGHASECVRNEFEKIVCNCKHNTFGSDCEKCLPFYNDRPWRRSTADSPNECLPCNCNGRSQECYFDPELYRSTGH--GGHCTGCADNTDGPNCERCRENYYR-----QDNNEPCHACQCNPVGSLS-TQCD-NYGRCSCKPGVMGEKCDRCQPGFHSLTEAGCRPC 432 HSP 2 Score: 79.337 bits (194), Expect = 1.773e-14 Identity = 56/160 (35.00%), Postives = 76/160 (47.50%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKC-HTIGSIKQNECDKKTGQCY-CRDGVTGQTCDRCKDGY 1402
C CNGH++ C D + CDC HNT G CERC Y + +T +A+ C+ C C S + + R T VC NC TTG CE C++G+F + C C+C + I CD+ TG+C C G CDRC+DG+
Sbjct: 711 CTCNGHSDTC---DPESGVCDCQHNTAGPHCERCSEGY----YGDSTTGSASDCQPCPCPGGS-----SCAVVPR---TKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPCRICECSNNIDPNAVGNCDRLTGECLKCIYNTGGFYCDRCRDGF 855 HSP 3 Score: 62.003 bits (149), Expect = 4.477e-9 Identity = 48/152 (31.58%), Postives = 66/152 (43.42%), Query Frame = 2
Query: 962 IDDNDEIKCD--------CHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCK 1393
ID N CD C +NT G C+RC+ + P QN ++ K C CN Y + N G C H T +C CE GF+ + C C CH++GS +CD +TGQC C G++GQ C +C+
Sbjct: 821 IDPNAVGNCDRLTGECLKCIYNTGGFYCDRCRDGFYGNPLA----QNPDL-KSCSCNP-----YGTVKGQSGCNQVTGQC--ECLPHVTERDCSACEPGFYNLLSG-----RGCERCDCHSLGSTS-GQCDVRTGQCECHPGISGQQCQQCE 954 HSP 4 Score: 52.7582 bits (125), Expect = 2.547e-6 Identity = 47/153 (30.72%), Postives = 62/153 (40.52%), Query Frame = 2
Query: 986 CDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY----KQSNSTVRPC 1432
C C GQ CERC Y + ++ + C C CN HS C S GVC +C+H+T G +CE C G++ + T + C C C S K+ C G TG+ C+ C DGY N RPC
Sbjct: 677 CSCPTGYIGQFCERCAPGYR---RENPSQGPYSPCVLCTCNGHSDTCDPES-----------GVC-DCQHNTAGPHCERCSEGYYGDSTTGSA--SDCQPCPCPGGSSCAVVPRTKEVVCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPC 812
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Ntn1 (netrin 1 [Source:MGI Symbol;Acc:MGI:105088]) HSP 1 Score: 391.734 bits (1005), Expect = 2.970e-126 Identity = 224/613 (36.54%), Postives = 335/613 (54.65%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI-----PSSGMADMANTSPVCK---KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+Q PC NG P++C+P F N +STCG P + C + E + C +C++ +++PP+ +TD + P N TCW S + P + V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + + P + IT N E +C + R G ++ FST+ GRPS + S L +W+T TD+R++ R F E L Y+ + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P + A C K ++ + ++ KK+CR+ + L + G+ ++ + I ++ K + R ++ WI S D+ C CPK++ + YL+L A+ + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYY---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKAGDWWKFTVNIISVY---KQGTSRIRRGDQSL-----WIRSRDIACKCPKIKPLKKYLLLGNAED--SPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Ntn1 (netrin 1 [Source:MGI Symbol;Acc:MGI:105088]) HSP 1 Score: 391.734 bits (1005), Expect = 2.970e-126 Identity = 224/613 (36.54%), Postives = 335/613 (54.65%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI-----PSSGMADMANTSPVCK---KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+Q PC NG P++C+P F N +STCG P + C + E + C +C++ +++PP+ +TD + P N TCW S + P + V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + + P + IT N E +C + R G ++ FST+ GRPS + S L +W+T TD+R++ R F E L Y+ + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P + A C K ++ + ++ KK+CR+ + L + G+ ++ + I ++ K + R ++ WI S D+ C CPK++ + YL+L A+ + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYY---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKAGDWWKFTVNIISVY---KQGTSRIRRGDQSL-----WIRSRDIACKCPKIKPLKKYLLLGNAED--SPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Ntn3 (netrin 3 [Source:MGI Symbol;Acc:MGI:1341188]) HSP 1 Score: 326.25 bits (835), Expect = 1.607e-101 Identity = 206/613 (33.61%), Postives = 298/613 (48.61%), Query Frame = 2
Query: 56 ILNLSVWIHSVKVIFESQSSPCYLNGR-PQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAF-KMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPV----CKK-CNEKRK--RIVFKKFCRRK-SVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLIL----TRAKYYLYLRNKELYIDSRSVMLPWHNSW 1840
+L ++ + + PCY R P+ C+P N + +STCG R +CD+ R++ +T + CW S LQ+ P V +TV L K+FE+ +++L+ C P S+A+ KS D G SW P FFS C + ++P + S P E LC AP+ D G +L FS G P G S L +W+T TD+RI L R + T + Y + ++L VGGRCKCNGHA+RCL+D + + CDC H TEG +C RCK Y DRPWQRAT Q A+ C C CN H+ RC FN ++Y + +GGVC+NCRH+T G +C C GF+R+ + R AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC G++QS S V PC+ + +SPV C+ C R RI KKFCR+ +V A E G+ R+ + + ++R + E R + A+ W+ + D C CP++ G+ YL+L A R + L S++LPW ++W
Sbjct: 9 LLTAGTLSAALSPGLPASADPCYDEAREPRSCIPGLVNAALGREVLASSTCG-------------------RSANRVCDSSDPQRAHSADLLTSAPGTASPLCWRSDLLQQAP--FNVTLTVPLGKAFELVFVSLRFCSAPPTSVALLKSQDHGRSWVPLGFFSSSCTLDYGRLPAPADGPSGPGP----EALC--FPAPQAQPDGGG---LLAFSVQDGSPQGLDLDNSPVLQDWVTATDIRIVLTRPAIQGDTRDGGVTVPYS---------------------YSATELQVGGRCKCNGHASRCLLDTHGHLVCDCQHGTEGPDCSRCKPFYCDRPWQRATGQEAHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRVLSDRRACRACDCHPVGAAGKT-CNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPCVKTPVPGPTEESSPVEPQDCESHCRPARGSYRISLKKFCRKDYAVQVAVGARGEARGSWTRFPVAVLAVFRSGE---ERARRGSSAL-----WVPTLDAACGCPRLLPGRRYLLLGGGPGAAAGSTAGRGQGLSAARGSLVLPWRDAW 561
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Lamc1 (laminin, gamma 1 [Source:MGI Symbol;Acc:MGI:99914]) HSP 1 Score: 236.498 bits (602), Expect = 1.327e-64 Identity = 160/467 (34.26%), Postives = 232/467 (49.68%), Query Frame = 2
Query: 128 NGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDA--KHRSYPPSHITDRHIPKNQTCWFSGPLQENPG-QNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQ-SNSTVRPC-IPSSGMADMANTSP---VCK 1483
GRPQ+C+P F N NV T+TCGT PE+ C + C +CDA +H + + +TD + + T W S + N +N+T+ L K+F++ Y+ L+ + P+S AIYK W P+Q++S C + + T + + LC + ++D + FST+ GRPS + L EW+T TD+R++L R F E + P LK YY +SD AVGGRCKCNGHA+ C+ ++ D++ C+C HNT G +CE+C + DRPW+RAT ++A+ C CDCN S CYF+ ++Y + GG C NCR +T G CE C FFR + AC+ C C +GS+ +CD G+C C+ GV G CDRC+ G+ + + RPC SG D N VCK
Sbjct: 42 GGRPQRCMPEFVNAAFNVTVVATNTCGTP-PEEYC---VQTGVTGVTKSCHLCDAGQQHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKAN---RGFIRTGGDEQQALCTD-----EFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYY-----------------------AISDFAVGGRCKCNGHASECVKNEFDKLMCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGH--GGHCTNCRDNTDGAKCERCRENFFRLG-----NTEACSPCHCSPVGSLS-TQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSTDECNVETGRCVCK 464 HSP 2 Score: 70.0922 bits (170), Expect = 9.086e-12 Identity = 47/134 (35.07%), Postives = 63/134 (47.01%), Query Frame = 2
Query: 992 CHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCK 1393
C +NT G C+RCK + P A+ CK C CN Y Q N G C H +G +C C+ G++ N Q C C CH +GS +CD +TGQC C+ G+TGQ C+RC+
Sbjct: 850 CIYNTAGFYCDRCKEGFFGNPL---APNPADKCKACACNP-----YGTVQQQSSCNPVTGQC--QCLPHVSGRDCGTCDPGYY-NLQSGQ----GCERCDCHALGSTN-GQCDIRTGQCECQPGITGQHCERCE 967 HSP 3 Score: 66.6254 bits (161), Expect = 1.258e-10 Identity = 54/204 (26.47%), Postives = 76/204 (37.25%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRAT------------------RQNANVCKYCDCNLHSYRCYFNSQIYVRNNY-TNG--------------------------GVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSI-KQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
C CNGH+ C D + CDC NT G CE+C Y + + VC +C RC Y + +NG G C+ C ++T G C+ C+ GFF N P C +C C+ G++ +Q+ C+ TGQC C V+G+ C C GY
Sbjct: 722 CTCNGHSETC---DPETGVCDCRDNTAGPHCEKCSDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTAGKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKEGFFGNPLAPNPAD-KCKACACNPYGTVQQQSSCNPVTGQCQCLPHVSGRDCGTCDPGY 921 HSP 4 Score: 54.299 bits (129), Expect = 7.106e-7 Identity = 43/140 (30.71%), Postives = 63/140 (45.00%), Query Frame = 2
Query: 983 KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
+C C + G++C C Y + Q+ C+ CDC+ N Q +R G C C+ TG +CE CE F P+ C C CH GS+ +C K+ G+C CR+G G CD+C++ Y
Sbjct: 902 QCQCLPHVSGRDCGTCDPGYYNL-------QSGQGCERCDCHALGST---NGQCDIRT-----GQC-ECQPGITGQHCERCETNHF--GFGPE----GCKPCDCHHEGSLSL-QC-KEDGRCECREGFVGNRCDQCEENY 1017
BLAST of Netrin-1 vs. Ensembl Mouse
Match: Lamc3 (laminin gamma 3 [Source:MGI Symbol;Acc:MGI:1344394]) HSP 1 Score: 233.417 bits (594), Expect = 1.396e-63 Identity = 159/479 (33.19%), Postives = 231/479 (48.23%), Query Frame = 2
Query: 29 VMIFIRTIAILNLSVWIHSVKVIFESQSSPCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ--NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEV-LCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQ-SNSTVRPC 1432
V+ + T+A ++++ I + CY GR Q+CLP F N +AE + TCG PE C + Q C D R + S++TD H P + T W+ P Q VN+T+SL K++E+ Y+ L+ + P+S AIYK W+P+Q++S C + + P + + P V C ++D + FST+ GRPS + + L EW+T TD+ ISL R F + R+ + YY + +SD +VGGRCKCNGHA+ C + ++ C C HNT G +CERC + DRPW R T ++AN C C+C+ HS C F+ ++Y + GG C CR HTTG +CE CE ++R W+ + C C CH GS+ +CD +G C C+ VTG CDRC G+ S RPC
Sbjct: 6 VLSLLATVA--SMALVIQETHFAAGADMGSCYDGVGRAQRCLPEFENAAFGRRAEASHTCGRP-PEDFCPHVGAPGAGLQCQRCDDADPGRR-HDASYLTDFHSPDDST-WWQSPSMAFGVQYPTSVNLTLSLGKAYEITYVRLKFHTSRPESFAIYKRTYASGPWEPYQYYSASCQKTYGRP----EGHYLRPGEDERVAFCTS-----EFSDISPLNGGNVAFSTLEGRPSAYNFEESPVLQEWVTSTDILISLDRLNTFGDDIFKDPRVLQSYY----------------------YAVSDFSVGGRCKCNGHASECEPNAAGQLACRCQHNTTGVDCERCLPFFQDRPWARGTAEDANECLPCNCSGHSEECTFDRELYRSTGH--GGHCQRCRDHTTGPHCERCEKNYYR-WSP----KTPCQPCDCHPAGSLSL-QCD-NSGVCPCKPTVTGWKCDRCLPGFHSLSEGGCRPC 439 HSP 2 Score: 83.1889 bits (204), Expect = 1.060e-15 Identity = 59/167 (35.33%), Postives = 81/167 (48.50%), Query Frame = 2
Query: 926 RCKCNGHANRCLIDDNDEIKCD--------CHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
RC+C+G+ +D N CD C +NT G CE C+ + ATR + C C C+L + + G C+ C + +G +C C GF+ Q R C SCKCH +GS+ +N+C KTGQC CR GVTGQ CDRC+ G+
Sbjct: 821 RCQCSGN-----VDLNAVGNCDPHSGHCLRCLYNTTGAHCEHCREGFYGSAV--ATRP-VDKCAPCSCDL-------RGSVSEKTCNPVTGQCV-CLPYVSGRDCSRCSPGFY----DLQSGRG-CQSCKCHPLGSL-ENKCHPKTGQCPCRPGVTGQACDRCQLGF 965 HSP 3 Score: 67.3958 bits (163), Expect = 6.137e-11 Identity = 60/198 (30.30%), Postives = 79/198 (39.90%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNE---CDKKTGQCY-CRDGVTGQTCDRCKDGYKQSNSTVRP---CIPSS----GMADMANTSPVCKKC 1489
C CN H D N I C C H+TEG CERC + + A A+ C+ C C S V VC +C G CE+CE+GFF + C C+C G++ N CD +G C C TG C+ C++G+ S RP C P S G +PV +C
Sbjct: 719 CTCNQHGT---CDPNTGI-CLCGHHTEGPSCERCMPGF----YGNAFSGRADDCQPCPCPGQSACATIPESGDV--------VCTHCPPGQRGRRCESCEDGFFGDPLGLSGAPQPCRRCQCS--GNVDLNAVGNCDPHSGHCLRCLYNTTGAHCEHCREGFYGSAVATRPVDKCAPCSCDLRGSVSEKTCNPVTGQC 898
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|Q90922|NET1_CHICK (Netrin-1 OS=Gallus gallus OX=9031 GN=NTN1 PE=1 SV=1) HSP 1 Score: 394.815 bits (1013), Expect = 1.318e-126 Identity = 227/618 (36.73%), Postives = 340/618 (55.02%), Query Frame = 2
Query: 92 VIFESQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIP---------SSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+ +Q PCY +G P++C+P F N + + +STCG P + C + E + C +C+A R++PPS +TD + P N TCW S + P + V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + + P+ + IT N E +C + R G ++ FST+ GRP+ + S L +W+T TD++++ R F E L Y + +SDL VGGRCKCNGHA+RC+ D +D + CDC HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ +KP HR AC C CH +G+ Q C++ TGQC C+DGVTG TC+RC GY+QS S + PCI +S + A+ CK K K I KK+C++ + L E + + ++ + I +++ N L R + W++++D+ C CPKV+ + YL+L + + D S+++ W ++W RRL+KFQ+REK+GKC +
Sbjct: 34 AVQTAQPDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCG-KPPSRYC--VVTEKGEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPS----RAAITKQNEQEAICTDSHTDVRPLSGG----LIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKECDCHPVGAAGQT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPAAPPPTAASSTEEPADCDSYCKASKGKLK-INMKKYCKKDYAVQIHILKAEKNADWWKFTVNIISVYKQGSNR---LRRGDQTL-----WVHAKDIACKCPKVKPMKKYLLLGSTED--SPDQSGIIADKSSLVIQWRDTWARRLRKFQQREKKGKCRK 605
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|O09118|NET1_MOUSE (Netrin-1 OS=Mus musculus OX=10090 GN=Ntn1 PE=1 SV=3) HSP 1 Score: 391.734 bits (1005), Expect = 2.077e-125 Identity = 224/613 (36.54%), Postives = 335/613 (54.65%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI-----PSSGMADMANTSPVCK---KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+Q PC NG P++C+P F N +STCG P + C + E + C +C++ +++PP+ +TD + P N TCW S + P + V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + + P + IT N E +C + R G ++ FST+ GRPS + S L +W+T TD+R++ R F E L Y+ + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P + A C K ++ + ++ KK+CR+ + L + G+ ++ + I ++ K + R ++ WI S D+ C CPK++ + YL+L A+ + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYY---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKMNMKKYCRKDYAVQIHILKADKAGDWWKFTVNIISVY---KQGTSRIRRGDQSL-----WIRSRDIACKCPKIKPLKKYLLLGNAED--SPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|P34710|UNC6_CAEEL (Netrin unc-6 OS=Caenorhabditis elegans OX=6239 GN=unc-6 PE=1 SV=1) HSP 1 Score: 391.349 bits (1004), Expect = 3.327e-125 Identity = 218/605 (36.03%), Postives = 337/605 (55.70%), Query Frame = 2
Query: 116 PCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCV--ELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTS-----PVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
PC+ + GRP +C+P F N + TCGTN P++ C + R+ C CDA++ +S+P S +TD + N TCW S P + V++T+SL K FE+ Y+++ C LPDS+A+YKS DFG +W P+QF+S +C R F + + IT +N E +C + P G PF + RPS + S L +W+T TD+++ R +P+++ ELY + + + N + + + + + +LAVGGRCKCNGHA+RC+ D CDC HNT G ECE CK + DRPW RAT +AN C C+CN H+ RC F+++++ + +GGVC+NCRH+T G NC C+ GF R+ + P HR AC SC CH +GS+ ++ C++ +GQC C+ GVTG TC+RC GY+QS STV PCI AD +S C KC KR+ KKFC+R + +S+E+ +Y++ ++ ++ K E + R ++ WI+ + V C CPK+ +G+ YL+L K L ++ ++V++ W + ++ +F K++K G+C +
Sbjct: 36 PCHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYC-TVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVSTP---SLSPQNVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFG----RDPDVSITKSNEQEAVCTASHIMGP------GGNRVAFPF--LENRPSAQNFENSPVLQDWVTATDIKVVFSRLSPDQA------ELYGLSNDV-NSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKACKSCGCHPVGSLGKS-CNQSSGQCVCKPGVTGTTCNRCAKGYQQSRSTVTPCIKIPTKADFIGSSHSEEQDQCSKCRIVPKRLNQKKFCKRDHAVQMVVVSREMVDGWAKYKIVVESVF---KRGTENMQRGETSL-----WISPQGVICKCPKLRVGRRYLLL--GKNDSDHERDGLMVNPQTVLVEWEDDIMDKVLRFSKKDKLGQCPE 606
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|O95631|NET1_HUMAN (Netrin-1 OS=Homo sapiens OX=9606 GN=NTN1 PE=1 SV=2) HSP 1 Score: 390.578 bits (1002), Expect = 5.425e-125 Identity = 224/613 (36.54%), Postives = 334/613 (54.49%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI-----PSSGMADMANTSPVCK---KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+Q PC NG P++C+P F N +STCG P + C + E + C +C+A +++PP+ +TD + P N TCW S + P + V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + + P + IT N E +C + R G ++ FST+ GRPS + S L +W+T TD+R++ R F E L Y + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P + A C K ++ + +I KK+C++ + L + G+ ++ + I ++ K + R ++ WI S D+ C CPK++ + YL+L A+ + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSVEEPEDCDSYCKASKGKLKINMKKYCKKDYAVQIHILKADKAGDWWKFTVNIISVY---KQGTSRIRRGDQSL-----WIRSRDIACKCPKIKPLKKYLLLGNAED--SPDQSGIVADKSSLVIQWRDTWARRLRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. UniProt/SwissProt
Match: sp|Q924Z9|NET1_RAT (Netrin-1 OS=Rattus norvegicus OX=10116 GN=Ntn1 PE=1 SV=1) HSP 1 Score: 385.571 bits (989), Expect = 4.529e-123 Identity = 223/614 (36.32%), Postives = 332/614 (54.07%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI---------PSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+Q PC NG P++C+P F N +STCG P + C + E + C +C++ +++PP+ +TD + P N TCW S + P + V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + + P + IT N E +C + R G ++ FST+ GRPS + S L +W+T TD+R++ R F E L Y+ + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI +S M + + CK K K + KK+CR+ + L + G+ ++ + I ++ K + R ++ WI S D+ CPK++ + YL+L A+ + D +++ W ++W RR +KFQ+REK+GKC++
Sbjct: 36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYY---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTAASSMEEPEDCDSYCKASKGKLK-MNMKKYCRKDYAVQIHILKADKAGDWWKFTVNIISVY---KQGTSRIRRGDQSL-----WIRSRDIAXKCPKIKPLKKYLLLGNAED--SPDQSGIVADKSXLVIQWRDTWARRXRKFQQREKKGKCKK 603
BLAST of Netrin-1 vs. TrEMBL
Match: Q49BF8 (Netrin 2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 902.123 bits (2330), Expect = 0.000e+0 Identity = 430/469 (91.68%), Postives = 443/469 (94.46%), Query Frame = 2
Query: 35 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPS 1441
IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCK C C HS +C F+ +Y + +GGVC+ C+H+T G+ C+ C +R+ TKP H ACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIP+
Sbjct: 1 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPT 469
BLAST of Netrin-1 vs. TrEMBL
Match: E1CHK4 (Netrin OS=Dugesia japonica OX=6161 GN=DjnetB PE=2 SV=1) HSP 1 Score: 852.047 bits (2200), Expect = 0.000e+0 Identity = 393/461 (85.25%), Postives = 431/461 (93.49%), Query Frame = 2
Query: 35 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNS 1417
+FI+T ILNLSVWIHSVKVI+ESQ+S CY NG+PQQCLPSFTNIIE+VK ETTSTCGTNGPEQICRNWYD++T EARQYCSICDAKHRSYPP H+TDRHIP NQTCWFSGPLQE GQNEVNITV+LKKSFEVYY+ALQICGTLPDSIAIYKSLDFGV+W+PWQFFSQDCYRAFKMPTTNEQNSQITP NI EVLCVELKAP+RYND+GQAETVLPFST GRPSGPPWSQ L+EWMTMT+L+ISLMRF P KSTP R KEL+YHTE+LP PN +N+K+EPIVHFGLSDLAVGGRCKCNGHA+RCLIDDNDEI+CDCHHNTEGQ+CERCKSNYLDRPW RATRQNANVCKYCDCNLHSYRC FN Q+YV+NN+TNGGVCINC+H+TTGNNCE C+NG++RNWTKPQEHR+AC SCKCHTIGSIK NEC KKTGQCYC+DGVTGQTCDRCK+GYKQ+NS
Sbjct: 1 MFIKTFVILNLSVWIHSVKVIYESQTSSCYSNGKPQQCLPSFTNIIEDVKVETTSTCGTNGPEQICRNWYDRSTTEARQYCSICDAKHRSYPPLHLTDRHIPNNQTCWFSGPLQEVSGQNEVNITVALKKSFEVYYVALQICGTLPDSIAIYKSLDFGVTWRPWQFFSQDCYRAFKMPTTNEQNSQITPTNIQEVLCVELKAPDRYNDFGQAETVLPFSTTVGRPSGPPWSQSLIEWMTMTNLKISLMRFPPVKSTPDRYKELFYHTETLPHGLPNSINYKSEPIVHFGLSDLAVGGRCKCNGHASRCLIDDNDEIRCDCHHNTEGQDCERCKSNYLDRPWHRATRQNANVCKYCDCNLHSYRCNFNHQLYVKNNFTNGGVCINCQHNTTGNNCEICQNGYYRNWTKPQEHRSACISCKCHTIGSIKPNECHKKTGQCYCKDGVTGQTCDRCKEGYKQTNS 461
BLAST of Netrin-1 vs. TrEMBL
Match: A0A4Z2D9H4 (Netrin-A OS=Schistosoma japonicum OX=6182 GN=EWB00_003107 PE=4 SV=1) HSP 1 Score: 574.704 bits (1480), Expect = 0.000e+0 Identity = 304/690 (44.06%), Postives = 399/690 (57.83%), Query Frame = 2
Query: 83 SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNG-PEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAP--------------PNLVNHKTEPI-----------------------------VHFGLSDLAVGGRCKCNGHANRCLID---------DND--------EIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------------------PSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPR-ETPAMHTYRAWI----NSEDVR---CNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCE 1891
+VKVI+E+ S CY G+ +C P FTNI E++ + TSTCG G E+ICR ++ C ICD+ + + +TDRH N+TCW SG + PG + VN+T+SL K FEVYYI+LQ CG LPDSIA+YKS DFG++WKPWQ+FS DCYRAF++PT+NE N+QI+ ANI EVLCV LK+P+ ++ G++ ++ FST GRPS PWS L++WMTMTDLRISLMRF P +E+ + + L P PN+ P VHF SDL++GGRCKCNGHANRC+ D +ND ++CDC HNTEG +CERC S YLDRPW R T ++AN CK CDCNLHS C F++Q+Y+ + +GGVC +C+H+T G C NC G++R+WTKP H C C+CH IGSI CD+KTGQC C+ GV GQ C+RC+DGYKQ+ PCI P+ C C +KRI FKKFCR ++VFR S+ IHG+++R E+ I WR+ LP+ +P + YR W+ NS D R C CP + +GQSYL +TR+ Y EL +DS+SV+L W SW RRL KF +R R C+
Sbjct: 42 NVKVIYEATRSVCYTKGQAIECSPPFTNIAESIDIKATSTCGQFGQSEEICR------YVLGQRKCDICDSSEK-FGTHLLTDRHQMNNETCWISGSVL--PG-DTVNLTLSLGKRFEVYYISLQPCGQLPDSIALYKSSDFGITWKPWQYFSTDCYRAFRLPTSNEHNAQISLANIQEVLCVALKSPDIHDAIGKSSNIIAFSTTIGRPSTQPWSSALIDWMTMTDLRISLMRF------PEHREEVQHDSNGLFLNPGLLKPSKVFRVSGSPNIGGFGINPALSETGALDMSQHLYQSDMHYAKTPNSKSPVHFSFSDLSIGGRCKCNGHANRCVRDRIVSTSSTKENDGLAKSQWGPLRCDCQHNTEGTDCERCSSGYLDRPWARGTSESANECKRCDCNLHSNSCIFSNQLYLMSMKVSGGVCQDCQHNTVGRRCHNCATGYYRDWTKPVSHDQVCLECRCHPIGSIANQHCDRKTGQCPCKPGVIGQACNRCQDGYKQTRLPDAPCIKAMEHYAHRRKENDQTSHPTKSQMSRLEPDTNCPPCERSKKRIRFKKFCRCEAVFRGIIKSRTIHGDLMRLEVGIQNTWRITGAAEHLLPKTASPNLPAYRVWLRIKNNSADKRHSFCLCPNLLVGQSYLFITRSHQVPYGDRMELLLDSQSVILRWRESWRRRLSKFVRRAARESCD 715
BLAST of Netrin-1 vs. TrEMBL
Match: A0A3Q0KPX7 (Putative netrin OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0 Identity = 306/690 (44.35%), Postives = 398/690 (57.68%), Query Frame = 2
Query: 83 SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGT-NGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAP--------------PNLVNHKTEPI-----------------------------VHFGLSDLAVGGRCKCNGHANRCLID---------DND--------EIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------------------PSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPR-ETPAMHTYRAWI----NSED---VRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCE 1891
++KVI+E+ S CY G+ +C P FTNI E+V + TSTCG + E+ICR + C C K + +TDRH N+TCW SG + PG + VN+T+SL K FEVYYI+LQ CG LPDSIA+YKS DFGV+WKPWQ+FS DCYRAF +PT+NE N+QI+ ANI EVLCV LK+P+ + + GQ+ V+ FST GRPS PWS L++WMTMTDLRISLMRF PE YR E+ Y + L P P++ T P+ VHF SDL++GGRCKCNGHANRC+ D DN+ ++CDC HNTEG +CERC YLDRPW R T ++AN CK CDCNLHS C F++Q+Y+ + +GGVC +C+H+T G C NC G++R+WTKP H C C+CH IGSI CD+KTGQC C+ GV GQ C+RC++GYKQ+ PCI + T+ C C +KRI FKKFCR ++VFR S+ IHG+++R E+ I WR+ LP+ +P + YR W+ NS D RC CP +++GQSYL +TR+ Y EL +D+ SV+L W SW RRL KF +R R C+
Sbjct: 42 NIKVIYEATRSVCYTKGQAIECSPPFTNIAESVDIKATSTCGQFDQSEEICR------YVMGHEKCETC-GKGEKFGTHLLTDRHQMNNETCWVSGSVL--PG-DTVNLTLSLGKRFEVYYISLQPCGQLPDSIALYKSSDFGVTWKPWQYFSTDCYRAFHLPTSNEHNAQISLANIQEVLCVALKSPDVHGNSGQSSNVIAFSTTIGRPSMQPWSSALIDWMTMTDLRISLMRF-PE----YR-DEVQYDSNGLFLNPSFLKPTNVFRVSGSPSIGGFGTNPVLSEAGTLDMSQHLYQSDMHYSKTPKSKTPVHFSFSDLSIGGRCKCNGHANRCIRDRIVGTGITTDNNGQTKSQWGPLRCDCQHNTEGADCERCSPGYLDRPWARGTSESANDCKRCDCNLHSNSCVFSNQLYLMSMKVSGGVCQDCQHNTVGRKCHNCVTGYYRDWTKPVSHDQVCLECRCHPIGSIANQHCDRKTGQCPCKPGVVGQACNRCQEGYKQTRLPDAPCIKAMEHYAHRRKENDQTSHSTKSQLSKPETNIDCPPCERSKKRIRFKKFCRNEAVFRGIVKSRTIHGDLMRLEVGIQNTWRITGAAEHLLPKTASPNLPAYRVWLRIKNNSADKRHSRCLCPNLQVGQSYLFITRSHQVPYGDRMELLLDTHSVVLKWRESWRRRLSKFVRRAARESCD 715
BLAST of Netrin-1 vs. TrEMBL
Match: A0A5K3F9D3 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1) HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0 Identity = 295/700 (42.14%), Postives = 394/700 (56.29%), Query Frame = 2
Query: 89 KVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNG-PEQICRNWYDKTTAEARQYCSICDAKHR--SYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRF-------------------------------TPEKSTPYRLK--ELYYHTESLP--QAPPNLVN-------------------HKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDE-------------IKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI----------------PSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWR-------------VDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCE 1891
KVI+ES +S CY + + C P FTNI E + TSTCG G E++C++W + + + YC CD++ S +TDRHI NQTCW SG + PG + VN+T+SL K FE++YI+LQ CG LPDSIA+YKS DFG +WKPWQ+FS DCYRAF +PT++E N+QI+ ANI EVLCV +K P +YN GQ V+ FST GRP+ WS L++WMTMTDL+ISL RF P+K+ +RL L++ L QA +N H + V+F SD+AVGGRCKCNGHANRC+ D E ++CDC HNT G +CERC YLDRPW RAT ++AN CK C+CNLHS C F+ Y+ + +GGVC +CRHHTTG C C GF+R+WTKP H C C+CH IGSI CD+KTGQC+C+ GVTGQTC+RC DGYKQ+ S + PC+ P + + C C + KR FKKFCRR++VFRAT +S+E G ++R ++I ++WR V +N +P P S V C CP+ ++ QSYL +++ + EL +D +S +LPW +W RRL +F R++RG+C+
Sbjct: 35 KVIYESPNSVCYADNKAYLCTPPFTNIAEGIPVVATSTCGQGGRAERVCKSWTSQNGQKRQTYCETCDSRKAATSRGAERLTDRHITSNQTCWVSGKVA--PG-STVNLTLSLGKRFEIFYISLQPCGPLPDSIALYKSSDFGRTWKPWQYFSTDCYRAFGLPTSSEHNAQISSANIQEVLCVAIKPPVKYNAQGQVSNVIAFSTTIGRPTSQSWSPALIDWMTMTDLQISLSRFPARRKSRTVERSGGDNTVVLHRRDRSSGQRRVPQKAPVFRLGGGRLFHQGAELEEMQADGTTLNATASTATNARNEVNTHEIHHDEDDAVYFAFSDIAVGGRCKCNGHANRCVRDRIVEKNAAGEEIVTWGPLRCDCQHNTVGADCERCAPGYLDRPWARATNEDANECKACECNLHSNSCTFSQYFYLLSKKVSGGVCEDCRHHTTGEKCHQCMEGFYRDWTKPISHPMVCLKCQCHPIGSIGSRPCDRKTGQCHCKTGVTGQTCNRCLDGYKQTRSKITPCVKAVDALVFAGSATRSSPQTSIVGQPTADDACPPCEKNNKRFRFKKFCRRQAVFRATVISQEARGELVRLVIRIHDVWRNKGSLAQRYLPAHVRRNQAPIIPLWVPLTKKPSTSRESHAV-CVCPRFKIDQSYLFISQVYEIPFHERNELLLDQKSTILPWVENWRRRLMRFAIRQERGRCD 730
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]) HSP 1 Score: 397.897 bits (1021), Expect = 6.401e-129 Identity = 229/612 (37.42%), Postives = 336/612 (54.90%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIP---------SSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
S PCY +G ++C+P F N + +STCG GP + C DK AR C CDA R++P S++TD + P N TCW S Q V +T+SL K FEV Y+++Q C PDS+AI+KS+D+G +W P+QF+S C + F P + IT N E +C + A R G ++ FST+ GRPS + S L +W+T TD+R++ R T P P + E + + +SDL VGGRCKCNGHA+RC+ + D + CDC HNT G EC+RCK + DRPWQRAT + A+ C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ +KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI +S + A+ CK K K I KK+C++ + L + G ++ + I +++ E R + W+ ++DV C CPK++ G+ YL+L + + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 32 SSPDPCYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGART-CHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRPN----RAAITKQNEQEAVCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLT------------------APGEP-----DEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTTASSPEEPADCDSYCKASKGKLK-INMKKYCKKDYAVQVHILKSDKAGEWWKFTVNIISVYKQG----ESRIRRGDQL----LWVRAKDVACKCPKIKTGKKYLLLGNDEDSPG--QSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 596
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]) HSP 1 Score: 399.438 bits (1025), Expect = 2.281e-127 Identity = 226/611 (36.99%), Postives = 338/611 (55.32%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI-----PSSGMADMANTSPVCK---KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
S PCY +G ++C+P F N + +STCG GP + C DK AR C CDA R++P S++TD + P N TCW S Q V +T+SL K FEV Y+++Q C PDS+AI+KS+D+G +W P+QF+S C + F P + IT N E +C + A R G ++ FST+ GRPS + S L +W+T TD+R++ R T P P + E + + +SDL VGGRCKCNGHA+RC+ + D + CDC HNT G EC+RCK + DRPWQRAT + A+ C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ +KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P + A C K ++ + +I KK+C++ + L + G ++ + I +++ ++ + R + W+ ++DV C CPK++ G+ YL+L + + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 209 SSPDPCYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGART-CHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRP----NRAAITKQNEQEAVCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLT------------------APGEP-----DEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAPPTTTASSPEEPADCDSYCKASKGKLKINMKKYCKKDYAVQVHILKSDKAGEWWKFTVNIISVYKQGES---RIRRGDQLL-----WVRAKDVACKCPKIKTGKKYLLLGNDED--SPGQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 773
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: ntn1b (netrin-1-like [Source:NCBI gene;Acc:111191060]) HSP 1 Score: 392.504 bits (1007), Expect = 1.401e-126 Identity = 225/618 (36.41%), Postives = 339/618 (54.85%), Query Frame = 2
Query: 95 IFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCK--------KCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKC 1888
+F +QSSP CY NG+P++C+P F N + +STCG + C + E + C CDA +++P +++TD + P N TCW S ++P QN V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + F P+ + IT N E +C + R A ++ FST+ GRPS + S L +W+T TD+R++ R F E L Y + +SDL VGGRCKCNGHA++C+ D D + C+C HNT G EC+RCK + DRPWQRAT + AN C C CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ TK HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI + A + + K ++ + ++ KK+C++ + L + G ++ + I +++ E R + W+ ++DV C CPK++ G+ YL+L ++ + D S+++PW + W RRL+KFQ+R+KRGKC
Sbjct: 46 VFAAQSSPPDPCYDENGQPRRCIPDFVNAAFGKEVRASSTCGAQTAARYC--VVTERGEERSRECHTCDAADPKKAHPAAYLTDLNNPHNLTCWQSESYVQHP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCKKMFNRPS----RAAITKQNEQEAVCTDSHTDMR----PLAGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASKCVKDRDGGGLVCECKHNTAGAECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMTKAISHRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVASPTATYTSAEEPTDCDSHCKASKGKMKVTMKKYCKKDFAVQVHVLKGDKAGEWWKFTINIISVYKQG----EHRIRRGDQL----LWVRAKDVACKCPKIKPGKKYLLLGSDDDDSRGQSG-VVADKGSLLIPWKDLWARRLRKFQQRDKRGKC 620
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029]) HSP 1 Score: 329.717 bits (844), Expect = 1.981e-101 Identity = 202/603 (33.50%), Postives = 303/603 (50.25%), Query Frame = 2
Query: 104 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
S PCY +G ++C+P F N + +STCG GP + C DK AR C CDA R++P S++TD + P N TCW S Q V +T+SL K FEV Y+++Q C PDS+AI+KS+D+G +W P+QF+S C + F P + IT N E +C + A R G ++ FST+ GRPS + S L +W+T TD+R++ R T P P + E + + +SDL VGGRCKCNGHA+RC+ + D + CDC HNT G EC+RCK + DRPWQRAT + A+ C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ +KP HR AC + P +S + A+ CK K K I KK+C++ + L + G ++ + I +++ ++ + R + W+ ++DV C CPK++ G+ YL+L + + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 209 SSPDPCYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGART-CHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRP----NRAAITKQNEQEAVCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLT------------------APGEP-----DEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKAC------------------------------------------KEIPVAPPTTTASSPEEPADCDSYCKASKGKLK-INMKKYCKKDYAVQVHILKSDKAGEWWKFTVNIISVYKQGESR---IRRGDQLL-----WVRAKDVACKCPKIKTGKKYLLLGNDED--SPGQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 723
BLAST of Netrin-1 vs. Ensembl Cavefish
Match: ntn1b (netrin-1-like [Source:NCBI gene;Acc:111191060]) HSP 1 Score: 323.553 bits (828), Expect = 1.092e-100 Identity = 200/610 (32.79%), Postives = 301/610 (49.34%), Query Frame = 2
Query: 95 IFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKC 1888
+F +QSSP CY NG+P++C+P F N + +STCG + C + E + C CDA +++P +++TD + P N TCW S ++P QN V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G +W P+QF+S C + F P+ + IT N E +C + R A ++ FST+ GRPS + L +W+T TD+R++ R F E L Y + +SDL VGGRCKCNGHA++C+ D D + C+C HNT G EC+RCK + DRPWQRAT + AN C C CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G++R+ TK HR AC + P + + + CK K K + KK+C++ + L + G ++ + I +++ E R + W+ ++DV C CPK++ G+ YL+L ++ + D S+++PW + W RRL+KFQ+R+KRGKC
Sbjct: 46 VFAAQSSPPDPCYDENGQPRRCIPDFVNAAFGKEVRASSTCGAQTAARYC--VVTERGEERSRECHTCDAADPKKAHPAAYLTDLNNPHNLTCWQSESYVQHP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCKKMFNRPS----RAAITKQNEQEAVCTDSHTDMR----PLAGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASKCVKDRDGGGLVCECKHNTAGAECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMTKAISHRRAC------------------------------------------KEIPVASPTATYTSAEEPTDCDSHCKASKGKMK-VTMKKYCKKDFAVQVHVLKGDKAGEWWKFTINIISVYKQG----EHRIRRGDQL----LWVRAKDVACKCPKIKPGKKYLLLGSDDDDSRGQSG-VVADKGSLLIPWKDLWARRLRKFQQRDKRGKC 570
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009682.1 (pep scaffold:Pmarinus_7.0:GL479835:738:11671:-1 gene:ENSPMAG00000008750.1 transcript:ENSPMAT00000009682.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 186.808 bits (473), Expect = 2.957e-53 Identity = 117/350 (33.43%), Postives = 175/350 (50.00%), Query Frame = 2
Query: 422 KSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY-KQSNSTVRPCI--PSSGMAD 1456
K+F++ Y+ L+ + P+S AIYK W P+Q++S C PT ++N + E L E + + FST+ GRPS + L +W+T T++R++L R + +HK ++ +SD AVGGRCKCNGHA+ C+ ++ + C C HNT G +CE+C Y DRPW RAT ++AN C CDCN + CYF+ ++Y + GG C NCR +T G CE C F+R EH C C C+ +GS + +CD++ G+C C+ GV G+ CD+C G+ + RPC P+ + D
Sbjct: 2 KAFDITYVRLKFHTSRPESFAIYKRASMDGPWTPYQYYSGSC-----EPTYGKRNRGFLRSGDDEQ--TPLCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQDWVTSTEIRVTLNRLNTFGDEVFN-------------------DHKVLRSYYYAISDFAVGGRCKCNGHASECVKNELGALACKCRHNTMGADCEKCLPLYNDRPWHRATSESANECTLCDCNGRADECYFDPELYRATGH--GGHCTNCRDNTDGKTCERCLENFYRR--SASEH---CLPCNCNPVGSYSR-QCDEQ-GRCSCKQGVMGERCDQCLPGFHSMDEAGCRPCTCNPAGTLED 316
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008925.1 (pep scaffold:Pmarinus_7.0:GL476496:30277:70426:-1 gene:ENSPMAG00000008054.1 transcript:ENSPMAT00000008925.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 147.517 bits (371), Expect = 1.423e-36 Identity = 109/382 (28.53%), Postives = 175/382 (45.81%), Query Frame = 2
Query: 428 FEVYYIALQICGT-LPDSIAIYKSLDFGVSWKPWQFFS---QDCYRAFKM-PTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRC-LIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQI-------YVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQ----------NECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRK 1504
F+V Y+ ++ + P + + +SLD G ++ PWQ++S +C + + PT + EV+C G+ T L I GRPS S L+++ + +R+ L R ++ L +L P V+ ++ + D++VGG C C+GHA+ C +D +++C C HNT G+ C+ C Y R W+ T N N C+ C+C+ + CY+++++ V ++ GGVC+NC +T G NCE C +GF+R C C+C GS+ Q E D GQC CR G G+ C+RC Y+ +PC+ S MA N P + C K +
Sbjct: 3 FQVAYVIVKAANSPRPGNWILERSLD-GATYHPWQYYSVSDSECLTRYGITPTVGNPVYR----RDDEVICTSYYVVLLMLARGKIHTSL----INGRPSADDPSPKLLDFTSARYIRLRLQR----------IRTLNADLMTLSHRDPREVDPIVTRRYYYSIKDISVGGMCICSGHASTCPWNEDTQKMECQCEHNTCGENCQHCCPGYNQRRWRPGTINNGNTCEKCNCHGKTEDCYYDAEVDRTNRSLSVHGRFSGGGVCVNCSANTAGTNCETCRDGFYRPTGVLPNDPYPCRLCQCDPQGSLSQVCIKDEKHADPEKDLSPGQCLCRPGFAGERCERCAFAYR-GYPDCKPCLCS--MAGGTNDDPCSEPCVCKER 362 HSP 2 Score: 71.2478 bits (173), Expect = 6.725e-13 Identity = 67/251 (26.69%), Postives = 97/251 (38.65%), Query Frame = 2
Query: 920 GGRC---KCNGHANRCLIDDNDEIKCD-------CHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLH----------------------------SYRCYFNSQIYVRNNYTNGGV-------------------------CINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY--KQSNSTVRPC----IPSSGMADMAN 1465
GGRC +C+GHA DD D++ D C HNT G CE C+ + + ATR A+ C C C L RC + + + GG C+ CR T G +CE C +GF+ + T C C+CH G+ +CD+ GQC CR V G+TC++C G+ S + PC + ++G+A A+
Sbjct: 619 GGRCEPCRCHGHA-----DDCDDLSGDCMLPLSGCRHNTMGPHCELCRPGF----YGNATRGTADDCLPCTCPLSIASNNFSPTCHQDPRGVLTCDQCLPGYIGLRCERCADDFFGEPSSPGGSCRRCECNGNEEAWGGGRVCDARTGQCLRCRERTAGFHCERCADGFYGDATG----TGGCQPCQCHPEGATAP-QCDRINGQCPCRPSVVGRTCEQCAIGFYGLSSGAGCSPCPCHPVGTAGVACSAD 855 HSP 3 Score: 51.9878 bits (123), Expect = 5.190e-7 Identity = 50/203 (24.63%), Postives = 71/203 (34.98%), Query Frame = 2
Query: 938 NGHANRCLIDDNDEIKCD-CHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNG--GVCINCRHHTTGNNCENCENGFF----------------RNWTKPQEHR-----------------------------AACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
N + C D + CD C G CERC ++ P C+ C+CN N + + + G C+ CR T G +CE C +GF+ T PQ R A C+ C CH +G+ C G+C+C GV G++CDRC G+
Sbjct: 688 NNFSPTCHQDPRGVLTCDQCLPGYIGLRCERCADDFFGEP-----SSPGGSCRRCECN-------GNEEAWGGGRVCDARTGQCLRCRERTAGFHCERCADGFYGDATGTGGCQPCQCHPEGATAPQCDRINGQCPCRPSVVGRTCEQCAIGFYGLSSGAGCSPCPCHPVGTAGV-ACSAD-GRCHCWPGVEGRSCDRCTSGH 876
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004606.1 (pep scaffold:Pmarinus_7.0:GL477874:5526:15188:-1 gene:ENSPMAG00000004198.1 transcript:ENSPMAT00000004606.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 113.235 bits (282), Expect = 7.181e-29 Identity = 75/231 (32.47%), Postives = 110/231 (47.62%), Query Frame = 2
Query: 422 KSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHE--VLCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD---LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNAN 1084
K+F++ Y+ L+ + P+S AIYK W+P+QF+S C R F +P+ A E LC + ++D + FST+ GRP + + EW+T TD+R+SL R F E P L+ YY +SDLAVGGRCKC+GHA+ C + + C C HNT G +CERC ++ RPW +A+ +A+
Sbjct: 4 KAFQITYVRLRFHTSRPESFAIYKRTSPASPWQPYQFYSGTCERTFGLPSRG-----FLRAGDEERTALCSD-----EFSDISPLTGGNVAFSTLEGRPGALAFDGNDKLQQEWVTATDVRVSLRRLNTFGDEVFGDPKVLRSYYY-----------------------AVSDLAVGGRCKCHGHASECGRGSDGRLVCRCQHNTTGDDCERCLPSHNSRPWAQASSDDAH 201
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004614.1 (pep scaffold:Pmarinus_7.0:GL477874:5547:15173:-1 gene:ENSPMAG00000004198.1 transcript:ENSPMAT00000004614.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 107.071 bits (266), Expect = 6.492e-27 Identity = 74/221 (33.48%), Postives = 103/221 (46.61%), Query Frame = 2
Query: 428 FEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHE--VLCVELKAPERYNDYGQAETV-LPFSTIYGR-PSGPPWSQDLVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRA 1066
F++ Y+ L+ + P+S AIYK W+P+QF+S C R F +P+ A E LC + ++D + FST+ G S P S EW+T TD+R+SL R F E P L+ YY +SDLAVGGRCKC+GHA+ C + + C C HNT G +CERC ++ RPW +A
Sbjct: 1 FQITYVRLRFHTSRPESFAIYKRTSPASPWQPYQFYSGTCERTFGLPSRG-----FLRAGDEERTALC-----SDEFSDISPLTGGNVAFSTLEGLFHSTGPLSSATQEWVTATDVRVSLRRLNTFGDEVFGDPKVLRSYYY-----------------------AVSDLAVGGRCKCHGHASECGRGSDGRLVCRCQHNTTGDDCERCLPSHNSRPWAQA 188
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003212.1 (pep scaffold:Pmarinus_7.0:GL478430:191288:204969:1 gene:ENSPMAG00000002937.1 transcript:ENSPMAT00000003212.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 87.8113 bits (216), Expect = 2.978e-19 Identity = 62/255 (24.31%), Postives = 111/255 (43.53%), Query Frame = 2
Query: 350 TCWFSGPLQENPGQNEVNITVSLKKSFEVYY-IALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVE------LKAPERYNDYGQAETVLPF--------STIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRAT 1069
T W S + +P VNIT+S K+ E+ + + P ++ + KSLD+G +W Q+++ DC+ F+ + +T A+ +V+C E + +R + F +++Y R G +L + T+TDLR L++ P ++ + ++ +S++ V GRC CN HA C + ++ C+C HNT G +C +CK + R W+ T
Sbjct: 59 TYWQSVSWRRHPEPLRVNITMSWGKTIELTDDVVITFESRRPSAMVLDKSLDYGRTWSAVQYYADDCHELFRREARRALD--LTQASATQVICTEEYSRSFVAKQDRTVRFEVLNRTALFAGVGLRNVASLYARLDG---DGELRRFFTLTDLRARLLQ---------------------PATGDTFIDKENLKKYYYAVSNVQVRGRCTCNLHAKECKFEKG-QLLCECEHNTTGSDCGKCKRGFRGRLWKAGT 286
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO36836 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHI5]) HSP 1 Score: 325.094 bits (832), Expect = 5.177e-102 Identity = 197/613 (32.14%), Postives = 306/613 (49.92%), Query Frame = 2
Query: 107 QSSPCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHR--SYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVE--LKAPERYNDYGQAETVLPFSTIYGRPSGPP--WSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEP--IVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI--PSSGMADMANT----SPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIW-RVDKNVWEFLPRETPAMHTYR---AWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKC 1888
Q+ CY R Q C P+F ++ N + TCG R + + R C CD ++ S+P ++TD H N TCW + P+Q + V + +S K++++ Y++LQ CG PDS+ IYKS+D+G SW+ +QF+S C + + T N +I+P N LC + L P YG + FST+ GRPS +S + EW+ TD+++ N+++ P +++ +S+ VGGRC CNGHA+ C+ D N CDC HNT G +C C+ + DRPW+ AT +AN CK C+CNLH+ C F+ +++ + +GGVC+ CRH+T G C C GF+++ K H C C CH GS + C++ TGQC C++GV G++CD+C GYK + S + PCI P+ M+ ++T C +C +R + K+FCR+ + T ++R E K+ W R N+ R WI D RC CPK++ G+SY I + R + + ++ RSV+LPW+ +R+ +F K ++ C
Sbjct: 1 QAKDCYNEFNRAQLCQPAFHDLAYNKDVYVSHTCGEKS-----RRFCPPMSVRGRTACGFCDERNAKTSHPAKYLTDVHNENNVTCWQADPVQS---RENVTLILSFGKTYDITYVSLQFCGIRPDSMGIYKSMDYGKSWQAYQFYSSRCEKMYGRVT----NGEISPENEQVALCTDGHLLRPL----YGGR---IAFSTLEGRPSASKMDYSAVMQEWVMATDIKVEF----------------------------NMISRSARPRDSLYYAVSEFNVGGRCHCNGHASECVSDRNGRQVCDCKHNTVGVDCGACRPFFNDRPWRPATHHSANECKMCNCNLHARTCVFSMELFKLSGGRSGGVCVKCRHNTAGRYCHYCREGFYKDPNKHITHIKVCRQCNCHPHGS-RGRVCNQSTGQCPCKEGVVGRSCDKCAPGYKSTKSNIVPCIETPNVVMSQESSTPRSRDQGCSQC--RRVPLKVKRFCRKDFALKVT---------VVRVEKKLPNSWVRATVNINTLFKRSRTRRVRRGDGYVWIKKRDFRCRCPKLKPGRSYFIAGNLRG--QSRKRSIVLNGRSVVLPWNEKLLKRIYRFIKLQRNNNC 552
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO36523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF3]) HSP 1 Score: 229.565 bits (584), Expect = 6.321e-63 Identity = 155/465 (33.33%), Postives = 230/465 (49.46%), Query Frame = 2
Query: 131 GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRS--YPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRC----LIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY-KQSNSTVRPCIPSSGMADMANTSPVCKKCNEK 1498
GR Q+C+P F N + + +TCG + P++ C E R+ C +C++ + +P ITD N+T W S L ENP + V +T+ L KS++V YI ++ P+S+AIYK W P+Q+FS C + + + T N + P N LC + + G + FST+ RP + S L EW+T +RI L R + PN++ ++ + DL++GGRCKCNGHA+ C L D ++C C H+TEG +CERCK Y DRPW RA+ +NAN C C+CN + C F+ +Y + + GG C NC+ +T G NCE C+ F+R + C +C C+ +GS+ +C+ + GQC C+ GVTG CD+C+ Y S + RPC T P +CNEK
Sbjct: 26 GRAQRCMPQFGNAAFGKRVISNNTCG-DPPKKFC---VQTGVLEVRKECEMCNSSDPALEHPALKITDIKDDTNRTWWQSETLLENPDK-PVTLTLDLGKSYDVSYIRIRFRSPRPESMAIYKKTTPSSKWIPYQYFSATCEKTYGVTT----NGIVDPRNQQVALCTDAFSTITPLTGGN----VAFSTLEDRPDAYNFDNSPALQEWVTAVAVRIHLRRMNTFGDEVF--------------GDPNVLRS-----YYYAIIDLSIGGRCKCNGHASECEETRLWDGQTRLQCKCQHDTEGVDCERCKPLYNDRPWARASSRNANECVRCNCNGLAESCVFDEALYRQTGH--GGRCQNCKQNTDGPNCERCKENFYR-----KTSLEPCVACGCNPVGSVSL-QCNSE-GQCRCKPGVTGIKCDKCQANYFGFSQTGCRPC-----QCFGPGTDPAKTQCNEK 444 HSP 2 Score: 67.781 bits (164), Expect = 1.388e-11 Identity = 56/167 (33.53%), Postives = 79/167 (47.31%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSC-KCHTIGSIKQN---ECDKKTGQCY-----CRDGVTGQTCDRCKDGY 1402
C+C GH++ C D KC+C HNT G C++C Y P T+ + CK C C + RC I + N VC +C GN C+ C++G++ + P R A T+C KC+ G+I N CD+ TG C R+G Q C+ C GY
Sbjct: 704 CQCYGHSDTC---DPVTGKCNCKHNTTGIRCDKCIDGYYGNP----TQGTPDDCKKCPCKFGT-RC-----IQIGANV----VCTDCPEGHVGNLCDMCQDGYYGD---PMGKRGAPTTCQKCNCSGNIDPNAIGSCDRLTGDCLKCIHNTRNGPISQ-CELCAIGY 849 HSP 3 Score: 52.373 bits (124), Expect = 7.388e-7 Identity = 32/94 (34.04%), Postives = 45/94 (47.87%), Query Frame = 2
Query: 1127 YFNSQIY--VRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
+F S +Y N N +C GNNCE C++G+ R + A C C+C+ + CD TG+C C+ TG CD+C DGY
Sbjct: 650 FFESAVYDPTSPNQVNWVEQCSCPKEYKGNNCEQCKDGYTRQAGSTDRY-AQCVPCQCYG----HSDTCDPVTGKCNCKHNTTGIRCDKCIDGY 738 HSP 4 Score: 51.9878 bits (123), Expect = 1.110e-6 Identity = 46/161 (28.57%), Postives = 68/161 (42.24%), Query Frame = 2
Query: 926 RCKCNGHANRCLIDDNDEIKCDCH---HNTEG---QECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRC 1390
+C C+G+ + I D + DC HNT +CE C Y + AT CK C+C + + + G C C + +G+ C+ C ++ + C C C T GS N C TGQC+C+ GVTG+ CD+C
Sbjct: 805 KCNCSGNIDPNAIGSCDRLTGDCLKCIHNTRNGPISQCELCAIGY----YGNATHYPKPQCKACECYVQGTVSPPGHDPTLPFPCDDKGRCT-CLPNVSGDKCDTCRPEYWNVASGK-----GCEPCNCDTTGSW-NNTCSVTTGQCHCKPGVTGRRCDQC 954
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO39502 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9X8]) HSP 1 Score: 179.489 bits (454), Expect = 2.083e-46 Identity = 124/451 (27.49%), Postives = 199/451 (44.12%), Query Frame = 2
Query: 140 QQCLPSFTNII---ENVKAETTSTCGTNGPEQICRNWYDKTTAEARQY--CSICDAKHRSYPPSHITDRHIPKNQTCWFSGPL-----QENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGR-----PSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEI-------KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKK--------TGQCYCRDGVTGQTCDRCKDGY 1402
+ C P+ +++ EN K +STCG GPE+ C + + Y C ICD++ P H+PK F G Q G+ V + + L+ F ++ ++ P + I +S D+G W+ +++FS DC + F E P +I +V+C N Y E I+ P +S + + +T++RI+ + L+ + L P + ++ + DL + G C C GHA +CL + +C+C HNT G+ CERC+ Y D PW+ A N N C+ C+CN H+ +C F+ +Y + +GGVC +C H+T G NCE C+ +++ +K AC +C C G + EC+ K G+C C+ V G CDRCK G+
Sbjct: 21 RSCYPATGDLLVGREN-KIYASSTCGLRGPEEYC------VVSNLQDYGDCHICDSRPYQTNPQF---SHVPKYMLSSFDGRKKDEWWQSENGRENVYLQLDLESEFHFTHLIMRFRTFRPAGMVIERSWDYGKKWQIYRYFSADCDKIFPGIPKGE------PKDIDDVICT--------NKYSTVEPSTNGEVIFRALKSQIPIKNAYSSKVQNLLKITNIRINFTK-------------LHTLGDDLLDPRPEIKRK-----YYYAVYDLVIRGSCSCYGHAEQCLPEPGQPTTPGMVYGRCNCTHNTTGKNCERCQDGYFDVPWRPADADNPNECRKCNCNGHAVKCRFDPAVYQASGNVSGGVCQDCEHNTVGRNCERCKPLHYQDPSKKFSDPDACIACNCDPTGGVNGGECEAKNDPAAGLVAGRCICKRNVGGVRCDRCKAGF 429 HSP 2 Score: 67.3958 bits (163), Expect = 2.006e-11 Identity = 60/215 (27.91%), Postives = 81/215 (37.67%), Query Frame = 2
Query: 929 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDC------NLHSYRCYFNSQI-------------------------YVRNNYTNGGVC------------------------INCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIK--QNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
C+C GHA+ C + + DC HNT G+ CE C + + AT+ N CK C C N S CY ++ Y N GG C + C ++T G NCE C+ G+F + CTSC C G+ C+ KTGQC C V G+ CDRC +G+
Sbjct: 850 CRCYGHASSC--NPKTGVCVDCQHNTVGKNCEACAVGF----YGIATKGTPNDCKRCQCPGGSSGNKFSESCYVDTSTTPPSVLCDKCQVGYTGRQCEECADGYYGNPLVPGGSCKPCSCNNNIDPTVSGNCDRLTGSCLQCLYNTAGFNCERCKPGYFGDAIARN-----CTSCVCDKKGTNPGFHYSCNHKTGQCNCLPDVEGKQCDRCAEGF 1053 HSP 3 Score: 58.151 bits (139), Expect = 1.223e-8 Identity = 46/171 (26.90%), Postives = 72/171 (42.11%), Query Frame = 2
Query: 983 KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNE 1495
+C+C + EG++C+RC + W ++ + C+ CDC + +QI G C C+ G C CE+ F W P + C++C C+ GS+ +CD+ TG+C C+ G G CD C AD + P C+ C E
Sbjct: 1034 QCNCLPDVEGKQCDRCAEGF----WNLSSGKG---CQQCDCCIEGSLRSMCNQIT--------GQC-QCKAGFGGPRCCECEDNF---WGSPPD---GCSACNCNPAGSVHL-QCDRDTGKCLCKVGHIGDKCDMC-------------------AADTSGKMPQCEICGE 1162 HSP 4 Score: 52.373 bits (124), Expect = 9.108e-7 Identity = 43/154 (27.92%), Postives = 63/154 (40.91%), Query Frame = 2
Query: 983 KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCY--------------CRDGVTGQTCDRCKDGY 1402
+C C + G++C C N P +C+ C C H+ C + GVC++C+H+T G NCE C GF+ TK + C C+C S +K + CY C+ G TG+ C+ C DGY
Sbjct: 822 QCQCRNWASGRQCSLCPPNMWGFP----------LCRPCRCYGHASSCNPKT-----------GVCVDCQHNTVGKNCEACAVGFYGIATKGTPND--CKRCQCPGGSSG-----NKFSESCYVDTSTTPPSVLCDKCQVGYTGRQCEECADGY 947
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO36501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF6]) HSP 1 Score: 159.844 bits (403), Expect = 4.248e-40 Identity = 127/463 (27.43%), Postives = 209/463 (45.14%), Query Frame = 2
Query: 59 LNLSVWIHSVKVIFESQSSPCYLNGR---PQQCLPS--FTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRS--YPPSHITDRHIPKNQTCWFSGP----LQENPGQN-EVNITVSLKKSFEVY-YIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYG-QAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNA-NVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
L + +++ +V + +S C+ N + Q C+P F +++ +TSTCG+ P + CR + C C+A + +P +I D+ + T W S Q+NP + +VN+++S K++++ +I P + KS D G +W P Q++S +C + F M T+ ++ K E+Y+ Q + F + + + ++++ TDLR L+ Y T+ L A + T ++ +SDL V RCKC+GHA C CDC HNT G +CERC + ++ W AT + N C+ C+C+ H+ C ++ Q Y G C +C H+T G+ CE C++ F+RN + H C C C G C++ TGQC CR VTG+ CD C D +
Sbjct: 4 LGMVLFLLTVSKV----NSECFENEKYDDVQTCVPEPRFAAKMKHRAVSSTSTCGSP-PSEYCR-------VKPLNGCFKCNASSPTERHPIEYIADKSPGSDATFWQSETWWDWYQKNPRDDLKVNVSISFNKTYDITGHIMFTFESPRPSKAILEKSFDKGQTWDPLQYYSFNCRKDFGMENTDPTENRFGD--------FSAKCTEKYSSSSPQQNGKVTFDFLRRYNKASFFDTQVQQYLSATDLR---------------LRMEYPGTDGLEVAKDEV----TLKQYYYAVSDLEVIARCKCHGHARWCDFPHETGKNCDCLHNTTGDDCERCLPLFNNKTWMPATSETEPNPCERCECHSHADSCTYSQQ----EGY---GTCDDCYHNTEGHFCERCKDKFYRNMSLSLNHPEICPDCNCFPQGITNNGTCNQTTGQCECRANVTGRQCDSCADTF 420 HSP 2 Score: 53.5286 bits (127), Expect = 3.314e-7 Identity = 54/205 (26.34%), Postives = 77/205 (37.56%), Query Frame = 2
Query: 926 RCKCNGHANRCLIDDNDEIKC--DCHHNTEGQECERCKSNY-------LDRP--------WQRATRQNAN---VCKYCDC--NLHSYRC----------------YFNSQIYVRNNYTNG--------GVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
RC+C+ HA+ C + DC+HNTEG CERCK + L+ P + + N C+C N+ +C Y + V N N G C +C+ + C+ C++G+ W P+ C C C GS+ Q C K TG C CR + G C GY
Sbjct: 325 RCECHSHADSCTYSQQEGYGTCDDCYHNTEGHFCERCKDKFYRNMSLSLNHPEICPDCNCFPQGITNNGTCNQTTGQCECRANVTGRQCDSCADTFWGYTLEPIGYCTECLCVGNGTVNASFNCDQYNGQC-SCKPNVHTRTCQECKHGY---WDFPKTLDTDCKRCDCDYGGSVLQ-ICSKTTGSCMCRTNIIGTRCTDVTTGY 524 HSP 3 Score: 53.1434 bits (126), Expect = 5.151e-7 Identity = 47/184 (25.54%), Postives = 69/184 (37.50%), Query Frame = 2
Query: 983 KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDC----------NLHSYRCYFNSQIYVRN---------NYTNGGVCINCR---------------------HHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSN 1414
KC C G+ C++CK + + ++ C CDC N S +C + R YT G C+ CR + T G C C GF+ N+T A C +C CH GS Q +C+ +TG C C+ G+ C+ C+ G S+
Sbjct: 753 KCQCKPGVTGRTCDKCKPGFYNF--------TSSGCAPCDCVSTGSHHLVCNAVSGQCPCKPGVITRTCSRCNDSFYGYTTGSGCVECRCNMSGSADAQCDDVTGNCTCKNSTDGAKCAECRFGFY-NFTS-----AGCQACNCHEGGSQSQ-QCNLQTGICTCKSNALGEKCESCRPGTYHSD 921 HSP 4 Score: 50.0618 bits (118), Expect = 3.975e-6 Identity = 22/51 (43.14%), Postives = 34/51 (66.67%), Query Frame = 2
Query: 1283 SCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDG-YKQSNSTVRPC 1432
+C C ++G+ + CD+ G+C C+ GVTG+TCD+CK G Y ++S PC
Sbjct: 733 ACGCDSVGTYLNSTCDRYGGKCQCKPGVTGRTCDKCKPGFYNFTSSGCAPC 783 HSP 5 Score: 49.6766 bits (117), Expect = 5.922e-6 Identity = 36/99 (36.36%), Postives = 48/99 (48.48%), Query Frame = 2
Query: 1169 GGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKD---GYKQSNSTVRPCIPSSGMAD 1456
GG C C+ TG C+ C+ GF+ N+T + C C C + GS C+ +GQC C+ GV +TC RC D GY + V SG AD
Sbjct: 751 GGKC-QCKPGVTGRTCDKCKPGFY-NFTS-----SGCAPCDCVSTGS-HHLVCNAVSGQCPCKPGVITRTCSRCNDSFYGYTTGSGCVECRCNMSGSAD 841
BLAST of Netrin-1 vs. Ensembl Nematostella
Match: EDO36500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF5]) HSP 1 Score: 147.517 bits (371), Expect = 2.682e-36 Identity = 128/484 (26.45%), Postives = 219/484 (45.25%), Query Frame = 2
Query: 53 AILNLSVWIHSVKVIFESQSS----PCYL--NGRPQQCLP--SFTNIIENVKAETTSTCGTN--------GPEQICRNWYDKTTAEARQYCSICDA----KHRSYPPSHITDRHIP-----------KNQTCWFSGPLQENPGQN--EVNITVSLKKSFEVY-YIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGY 1402
A L + + S+ V SQ++ CY GR C+P SF ++ NV T++TCGT GPE C CDA + +P +++ D + ++QT W + L + +N +VNIT+S K +++ +I P ++ KS DFG +W+ ++ C R + M E S PAN ++ C E + G ++ F ++ ++ +++++TD+R+ L E ++ LY ++L + +++ +S++ V GRC CNGHA C +C+C HNT G +CE C+ + +RPW RA + + N C+ C+CN H+ C +N + G+C C+H+T G++C+NC +R+ +KP H AC + + Q ++ GQC C+ V G+ CD+C G+
Sbjct: 6 ATLEILCVVGSLVVCLNSQNTCRFETCYERDTGRATPCMPFTSFMSLTRNVT--TSNTCGTTRAKYCELPGPEP----------------CYYCDANSSNSNEQHPVTNLVDNELVLPFYAQKYTWWQSQTWWETNQLGLSSIENPPKVNITLSFGKRYQLSGHIKATFYSKRPKAMCFDKSNDFGHTWETLLCYAWRCDRFYNM----EPQSNPDPANPFKLYCTEEYSGHEPRKLG----IVEFIASKRYEICDYFNPEVQDYLSVTDVRLRL-----EYPASDGMELLYQDEQTLNK-------------LYYAISNVEVTGRCSCNGHAMGCSGPIMSR-RCECEHNTMGTDCEMCEPLFNNRPWMRANQTHGNECQECNCNNHATSCVYNETLGY-------GLCKGCQHNTQGDHCQNCTAKHYRDLSKPINHVNACLGIT-NNGSCLTQATDTEQIGQCSCKPNVYGRRCDQCIPGH 436 HSP 2 Score: 61.6178 bits (148), Expect = 1.209e-9 Identity = 50/156 (32.05%), Postives = 69/156 (44.23%), Query Frame = 2
Query: 983 KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCEN---GFFRNWTKPQ---EHRAACTSCKCHTIGSIKQNE--CDKKTGQCYCRDG--VTGQTCDRCKD-GYKQSNS 1417
+ +CH N G CE C Y +P + C C CN S C+ + GVC +C+ T G CE C N G KPQ + C +C C+ G++ N CD+ TGQC C + GQ CDRC++ Y +S+S
Sbjct: 1073 RAECHRNYTGLSCEVCAEGYTRQPMGGTP---FDRCVLCSCNDRSRFCHPET-----------GVCTDCKIGTHGYRCELCTNNVQGPECVRCKPQYWGLSKDGCKACDCNLPGTLYSNTSVCDQTTGQCSCNATLHIGGQLCDRCEENAYNKSDS 1214
BLAST of Netrin-1 vs. Ensembl Medaka
Match: NTN1 (netrin-1 [Source:NCBI gene;Acc:101155405]) HSP 1 Score: 397.127 bits (1019), Expect = 1.384e-128 Identity = 232/650 (35.69%), Postives = 350/650 (53.85%), Query Frame = 2
Query: 32 MIFIRTIAILNLSVWIHSV-----KVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI---------PSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVW----EFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
M+ +L S+W S +F +Q+SP CY +G P++C+P F N + + +STCG P + C + E + C CDA + +PP+++TD + P N TCW S + P QN V +T+SL K FEV Y++LQ C P+S+ IYKS+D G +W P+QF+S C + + P + IT N E +C + + Y ++ FST+ GRPS + S L +W+T TD+++ R F E L Y + +SDL VGGRCKCNGHA+RC+ D + + CDC HNT G EC+RCK + DRPWQRAT + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ +KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P+S + ++ CK K K I KK+C++ + L + G ++ + I +++ ++ +FL W+ ++DV C CPK++ G+ YL+L + + + D S+++ W ++W RRL+KFQ+REK+GKC++
Sbjct: 1 MMRAVHAVLLAASLWCRSAFGGYGIGLFAAQTSPPDPCYDEHGNPRRCIPDFVNAAFGKEVKVSSTCGKT-PSRYCVVTSAEKGEERTRNCHSCDASDPKKYHPPAYLTDLNNPHNLTCWQSENFIQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMVIYKSMDNGKTWVPFQFYSTQCRKMYNKP----NRAVITKQNEQEAVCTD----SHTDMYPLTGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVVFSRLHTFGDENEDDSELARDSY---------------------FYAVSDLQVGGRCKCNGHASRCVKDRDGSLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVSPPTTPASSTEEASDCESYCKASKGKLK-INMKKYCKKDYAVQVHILKADKMGEWWKFTVNIISVYKQGESRIRRGDQFL------------WVRAKDVACKCPKIKPGKKYLLLGNDE--VSPSQSGVVADKGSLVIQWRDTWARRLRKFQQREKKGKCKK 602
BLAST of Netrin-1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359]) HSP 1 Score: 390.578 bits (1002), Expect = 1.243e-125 Identity = 228/645 (35.35%), Postives = 346/645 (53.64%), Query Frame = 2
Query: 50 IAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------PS---SGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKE-------------LYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+ +L SV HS F Q +P CY G ++C+P F N + +S CG P + C + + C ICDA R++P S++TD + N TCW S L +P + V +T+SL K FE+ Y++LQ C P+S+AIYKS+D+G +W P+QF+S C R + P + IT N E LC + + Y + ++ FST+ GRPS + S L +W+T+TD+R+ R P+ S + L + + + + T + + D VGGRCKCNGHA+RCL D ++ CDC HNTEG EC+RCK + DRPWQRA + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ +P HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S V PCI P+ S + A+ CK K I KK+C++ + L E G+ ++ + + ++ K+ E L R + W++ +D+ C CPK+++ + +L++ ++ L D S+++ W + W RRL+KFQ++EK+GKC +
Sbjct: 11 LFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCG-RPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKP----NKATITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGA---GSNNGGRDDDPVAVTSTLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVVNPTAVVSSTEEPADCESYCKPVKGNLK-INMKKYCKKDYAVQVNVLDMETVGDWAKFSVSLVSVY---KSRGEPLKRGDNIL-----WVHMKDLACKCPKIQMSKKFLVMGGSEGGTGPAAGPGVGATSPGAERVGLVADKNSLVIQWRDVWSRRLRKFQRKEKKGKCSK 629
BLAST of Netrin-1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359]) HSP 1 Score: 390.578 bits (1002), Expect = 1.243e-125 Identity = 228/645 (35.35%), Postives = 346/645 (53.64%), Query Frame = 2
Query: 50 IAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------PS---SGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKE-------------LYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+ +L SV HS F Q +P CY G ++C+P F N + +S CG P + C + + C ICDA R++P S++TD + N TCW S L +P + V +T+SL K FE+ Y++LQ C P+S+AIYKS+D+G +W P+QF+S C R + P + IT N E LC + + Y + ++ FST+ GRPS + S L +W+T+TD+R+ R P+ S + L + + + + T + + D VGGRCKCNGHA+RCL D ++ CDC HNTEG EC+RCK + DRPWQRA + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ +P HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S V PCI P+ S + A+ CK K I KK+C++ + L E G+ ++ + + ++ K+ E L R + W++ +D+ C CPK+++ + +L++ ++ L D S+++ W + W RRL+KFQ++EK+GKC +
Sbjct: 11 LFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCG-RPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKP----NKATITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGA---GSNNGGRDDDPVAVTSTLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVVNPTAVVSSTEEPADCESYCKPVKGNLK-INMKKYCKKDYAVQVNVLDMETVGDWAKFSVSLVSVY---KSRGEPLKRGDNIL-----WVHMKDLACKCPKIQMSKKFLVMGGSEGGTGPAAGPGVGATSPGAERVGLVADKNSLVIQWRDVWSRRLRKFQRKEKKGKCSK 629
BLAST of Netrin-1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359]) HSP 1 Score: 390.578 bits (1002), Expect = 1.243e-125 Identity = 228/645 (35.35%), Postives = 346/645 (53.64%), Query Frame = 2
Query: 50 IAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------PS---SGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKE-------------LYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQ 1894
+ +L SV HS F Q +P CY G ++C+P F N + +S CG P + C + + C ICDA R++P S++TD + N TCW S L +P + V +T+SL K FE+ Y++LQ C P+S+AIYKS+D+G +W P+QF+S C R + P + IT N E LC + + Y + ++ FST+ GRPS + S L +W+T+TD+R+ R P+ S + L + + + + T + + D VGGRCKCNGHA+RCL D ++ CDC HNTEG EC+RCK + DRPWQRA + AN C C+CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ GF+R+ +P HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S V PCI P+ S + A+ CK K I KK+C++ + L E G+ ++ + + ++ K+ E L R + W++ +D+ C CPK+++ + +L++ ++ L D S+++ W + W RRL+KFQ++EK+GKC +
Sbjct: 11 LFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCG-RPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKP----NKATITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGA---GSNNGGRDDDPVAVTSTLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPVAPCIKIPVVNPTAVVSSTEEPADCESYCKPVKGNLK-INMKKYCKKDYAVQVNVLDMETVGDWAKFSVSLVSVY---KSRGEPLKRGDNIL-----WVHMKDLACKCPKIQMSKKFLVMGGSEGGTGPAAGPGVGATSPGAERVGLVADKNSLVIQWRDVWSRRLRKFQRKEKKGKCSK 629
BLAST of Netrin-1 vs. Ensembl Medaka
Match: ntn1b (netrin-1 [Source:NCBI gene;Acc:101161061]) HSP 1 Score: 389.423 bits (999), Expect = 1.360e-125 Identity = 229/640 (35.78%), Postives = 347/640 (54.22%), Query Frame = 2
Query: 29 VMIFIRTIAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQN-SQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCI------PSSGMADMANTSPVCKKC--NEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKC 1888
+ I + T++ + +F +QSSP CY NG P++C+P F N +STCG N + C + E + C CD+ +++PP+++TD + P N TCW S + P QN V +T+SL K FEV Y++LQ C P+S+AIYKS+D+G SW P+QF+S C + + N QN + IT N E +C + + + ++ FST+ GRPS + S L +W+T TD+++ R F E L Y + +SDL VGGRCKCNGHA++C+ D + C+C HNT G EC+RCK + DRPWQRAT + AN C C CNLH+ RC FN ++Y + +GGVC+NCRH+T G +C C+ G+FR+ +KP HR AC +C CH +G+ + C++ TGQC C+DGVTG TC+RC GY+QS S + PCI P+S + S C ++ + +I KK+C++ + L + G ++ + I +++ ++ + R + W+ ++DV C CPK++ G+ YL+L + + D S+++PW + W RRL+KFQ+R+KRGKC
Sbjct: 7 IWISLLTVSAVTTGALAGYGLSMFAAQSSPPDPCYDENGNPRRCIPDFVNSAFGKDVRVSSTCG-NPAARFC--VVSEKGEERTRDCHTCDSNDPKKAHPPAYLTDLNNPHNLTCWQSETYVQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKSWVPFQFYSTQCKKMY-----NRQNKATITKQNEQEAICTD----SHTDMHPLTGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVIFSRLHTFGDENEDDSELARDSY---------------------FYAVSDLQVGGRCKCNGHASKCVKDREGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYFRDMSKPISHRRACKACDCHPVGAAGKT-CNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVASPTSTYSSYEEPSDCDSYCKASKGKMKITMKKYCKKDYAVQVHVLKGDKAGEWWKFTVNIISVYKQGRHR---IRRGDQLL-----WVRAKDVACRCPKIKPGRKYLLLGTDDD--SPGHSGVVADKGSLLIPWKDLWGRRLRKFQQRDKRGKC 600
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1) HSP 1 Score: 1364.75 bits (3531), Expect = 0.000e+0 Identity = 684/684 (100.00%), Postives = 684/684 (100.00%), Query Frame = 2
Query: 32 MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFXXXXXXXXXXXXXXXXQTKLXXXXXXXXXXXXXXVKENVPVYEKFHDTKYNPNYGYYGTHK 2083
MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFKKKMKIIDKSKIDESIQTKLKPKPKPKPKPKPKPVKENVPVYEKFHDTKYNPNYGYYGTHK
Sbjct: 1 MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFKKKMKIIDKSKIDESIQTKLKPKPKPKPKPKPKPVKENVPVYEKFHDTKYNPNYGYYGTHK 684
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1) HSP 1 Score: 1281.16 bits (3314), Expect = 0.000e+0 Identity = 646/684 (94.44%), Postives = 658/684 (96.20%), Query Frame = 2
Query: 32 MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFXXXXXXXXXXXXXXXXQTKLXXXXXXXXXXXXXXVKENVPVYEKFHDTKYNPNYGYYGTHK 2083
MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCK C C HS +C F+ +Y + +GGVC+ C+H+T G+ C+ C +R+ TKP H ACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFKKKMKIIDKSKIDESIQTKLKPKPKPKPKPKPKPVKENVPVYEKFHDTKYNPNYGYYGTHK
Sbjct: 1 MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYFKKKMKIIDKSKIDESIQTKLKPKPKPKPKPKPKPVKENVPVYEKFHDTKYNPNYGYYGTHK 684
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1) HSP 1 Score: 797.734 bits (2059), Expect = 0.000e+0 Identity = 381/420 (90.71%), Postives = 393/420 (93.57%), Query Frame = 2
Query: 32 MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCK 1291
MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCK C C HS +C F+ +Y + +GGVC+ C+H+T G+ C+ C +R+ TKP H ACTS K
Sbjct: 1 MIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTSEK 420
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000076695.1 (SMESG000076695.1) HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0 Identity = 276/644 (42.86%), Postives = 393/644 (61.02%), Query Frame = 2
Query: 35 IFIRTIAILNLSVWIH-SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICD--AKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNL----VNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPS---------------SGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLPRETPAMHTYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDSRSVMLPWHNSWERRLQKFQKREKRGKCEQYF 1900
+I +L S + ++ V++E++ + C +G+ C P F NI + K TS+CG P+ IC +W ++ R CSICD K+ Y +TD N TCWFSGP+ G N VNI+++ KK+FEV+Y+ALQ C LPDSI IYKS D G W PWQ++S++C +AF +P T E Q C +L ++ + GQAE++LPFS+ GR + L++W+T+TDLRI+L RF + S+ + + + + N+ VN K+ V++G+SDL+VGGRC+C GH+N+C+I+++ I CDC HNTEG +C++CK + D W+RA++ N CK C CNLHS C F +Y++ +GGVC C+H+T GN C C+NG++R+WTKP H AC CKCH +GS N CDKK GQC+C++GV G+ CD+CK GY Q+ S ++PC+ + S DM NT CK C+EKRKRI FKKFCRR SVF SKE+HG M+R+EL+I E+WRV + +F+ + + WI+ E+VRC+CP + LG+SYLIL + K Y + +EL +DSR+VML W SWERRLQKFQ + KCE++
Sbjct: 4 FLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRD-CSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRK----MNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLACKKCKCHAVGSTNVNSCDKKLGQCFCKEGVIGRKCDKCKIGYLQTRSMLKPCVKTYDIIESSQTKKSDLNSKYMDMPNTESECKPCDEKRKRIRFKKFCRRDSVFMGVIESKEVHGKMVRFELQIKEVWRVSGKISQFISEISQEQYAVPLWISHEEVRCDCPNISLGRSYLILMKYKIYHHRHREELLLDSRTVMLQWRPSWERRLQKFQTKANEEKCEKFL 642
BLAST of Netrin-1 vs. Planmine SMEST
Match: SMESG000069610.1 (SMESG000069610.1) HSP 1 Score: 439.884 bits (1130), Expect = 2.995e-145 Identity = 236/618 (38.19%), Postives = 344/618 (55.66%), Query Frame = 2
Query: 113 SPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGT-LPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHE----VLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRF---TPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDD-NDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACTSCKCHTIGSIKQNECDKKTGQCYCRDGVTGQTCDRCKDGYKQSNSTVRPCIPSSGMADMANTSPVCKKCNEKRKRIVFKKFCRRKSVFRATALSKEIHGNMIRYELKIDEIWRVDKNVWEFLP--------RETPAMH-----TYRAWINSEDVRCNCPKVELGQSYLILTRAKYYLYLRNKELYIDS-RSVMLPWHNSWERRLQKFQKREKRGKCEQY 1897
SPCY +G QC+P FTNI+EN+ + + C + ++ C I +S + ITD H+ NQTCW S PLQ N VNIT S K FEVYYI+L C + +P++IA YKS +FG++WKPW + + +C F M T + Q I C LK N E V+ F+T+ L++WM+ +D+RI+L +F P+KS +R + P +SD+++GGRCKCNGHAN C + ++I+C C HNTEGQ+CE+CK NYLD PW RAT + CK C+CNLHS CYF+ +Y+ GGVC NC+H+T G C C +G++R+WTKP +H+ C C CH IG+ + CDK+TGQC C+ GVTG+ C+RC G++QSNST PC+ M N CK C+ KR RI F+KFCR+ +VF T S+EI G+ IR+++ +D IW ++ + P R + T W+ D++CNC +++LGQ+YL + ++ Y Y EL I S RS++L W+ +W+RRL +F++++++G+C ++
Sbjct: 7 SPCYAHGSAYQCMPPFTNIVENMIPKIETLC------------------KKKEVCPI-----KSPRDNLITDYHLTHNQTCWKSVPLQAN----HVNITFSFAKRFEVYYISLTPCESGIPNAIAFYKSNNFGITWKPWHYLATNCLSMFNMKETTIPSLQFNDFRIQRREQAARCFPLKLSLTDN-----EPVVAFNTVLEGAYENVGDSSLIDWMSASDIRITLFKFDNPKPKKSNIFRFA-------------------RNSPKKILSISDISIGGRCKCNGHANACNKNPITNKIECVCQHNTEGQDCEKCKKNYLDLPWARATVNSPAQCKKCECNLHSSNCYFSQDLYILRKQITGGVCTNCQHNTAGVRCHYCNDGYYRDWTKPLDHKFVCKKCTCHIIGAKFPDRCDKRTGQCLCKSGVTGEMCNRCASGFRQSNSTETPCVKYIQMESAENK---CKACDSKRTRIRFRKFCRKDAVFSVTLQSQEIIGDFIRFDVTVDNIWHSKNSIKDLYPGIFIESIMRPSSKSRLNNRPTNPIWLKLRDLKCNCVQLQLGQTYLFIIKSTTYHYQNRAELLIKSPRSIILIWNPTWKRRLNRFKQKKEKGECSKF 570 The following BLAST results are available for this feature:
BLAST of Netrin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Netrin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Netrin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Netrin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Netrin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Netrin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015232 ID=SMED30015232|Name=Netrin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2364bpback to top protein sequence of SMED30015232-orf-1 >SMED30015232-orf-1 ID=SMED30015232-orf-1|Name=SMED30015232-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=695bp EYLHVYRFFVMIFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLback to top Aliases
The feature 'Netrin-1' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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