Protocadherin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015204 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 245.743 bits (626), Expect = 7.956e-66 Identity = 230/812 (28.33%), Postives = 398/812 (49.01%), Query Frame = 3
Query: 210 FIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFVK-ADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSAT--DMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
F + L+ V F + + + ++E +LIG+L ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ T D D++ + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E + K++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y+F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P +++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 42 FAVLLVCVVF---HSGAQEKNYTIREEIPENVLIGNL-----LKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG-INGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLP-----STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 809
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 243.817 bits (621), Expect = 8.685e-66 Identity = 230/812 (28.33%), Postives = 398/812 (49.01%), Query Frame = 3
Query: 210 FIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFVK-ADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSAT--DMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
F + L+ V F + + + ++E +LIG+L ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ T D D++ + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E + K++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y+F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P +++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 42 FAVLLVCVVF---HSGAQEKNYTIREEIPENVLIGNL-----LKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLP-----STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 809
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 243.432 bits (620), Expect = 8.796e-66 Identity = 230/812 (28.33%), Postives = 397/812 (48.89%), Query Frame = 3
Query: 210 FIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFVK-ADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
F + L+ V F + + + ++E +LIG+L ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ TD D + + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E + K++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y+F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P +++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 31 FAVLLVCVVF---HSGAQEKNYTIREEIPENVLIGNL-----LKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLP-----STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 798
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 243.432 bits (620), Expect = 8.796e-66 Identity = 230/812 (28.33%), Postives = 397/812 (48.89%), Query Frame = 3
Query: 210 FIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFVK-ADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
F + L+ V F + + + ++E +LIG+L ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ TD D + + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E + K++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y+F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P +++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 31 FAVLLVCVVF---HSGAQEKNYTIREEIPENVLIGNL-----LKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLP-----STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 798
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH11Y (protocadherin 11 Y-linked [Source:HGNC Symbol;Acc:HGNC:15813]) HSP 1 Score: 243.432 bits (620), Expect = 1.151e-65 Identity = 230/812 (28.33%), Postives = 397/812 (48.89%), Query Frame = 3
Query: 210 FIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFVK-ADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
F + L+ V F + + + ++E +LIG+L ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ TD D + + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E + K++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y+F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P +++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 42 FAVLLVCVVF---HSGAQEKNYTIREEIPENVLIGNL-----LKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGI-NGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLP-----STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 809
BLAST of Protocadherin vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 150.599 bits (379), Expect = 2.929e-36 Identity = 162/590 (27.46%), Postives = 275/590 (46.61%), Query Frame = 3
Query: 789 LRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQ--NENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH-FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
+R+ ++DRE ++K L + A + P ++ ST + +++ D+ DNSP+F K I+E+ I + +FA+DLD +N ++ +S G ++ IN K+G I LD + L I T E+ +V++ + NDNAPV + + S NV ++ ENI IA++ ATD D + S + + + D S + L + +D + N A I+ +D P +T + I V+D ND P AA + ++E V + V ++ A D D G N + Y ++ + F IDE++G+++T + DRE T Y L+ T D P+ L+++T I V++KDIND AP F K Y +I E + ++ A D+D + ++I+Y + E S + G I + L R+ + + I A D G + R V+V I+D+N + +D S+ I +G V LKA D D G N+ + Y I + + F+++ SG + + D ++V SD PL +T + +
Sbjct: 222 IRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEG---NGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFA-----SDSYNVTIL-ENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYST---GEVTLRERIDAK-NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDM-----GTPS---LNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDED---QKITYRIEEADREVFS-----ILDIGDQGAILSVSGELKRQDHKVR-VEISATDQGGLQGRCVVNVF--IDDVNSA----PYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI---DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEV 772 HSP 2 Score: 128.642 bits (322), Expect = 1.580e-29 Identity = 167/673 (24.81%), Postives = 298/673 (44.28%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETI-LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILL--TKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEK-VLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEH---ELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTT 2537
+ + + D+ D+SP++ + I E + IG+ A+DLDS + I Y+L N L + N+ +++ A +DRE + I L ++A D G+P + + I + D+NDN+PVF ++I EN I + + A D D N K+ +S +S I I+ G++ +++ +D T ++ + + T+ L + V + ND+AP + ++ ++ +EEN+ + + A D D+ +G +K S ++ ++ + + L+ TK LDRET + + +D G P T+ I + + D ND P F V I E +P S + L A D D + ++ YRI+ A + + +I +GE K + D + V+ T++ L ++ V I D+N AP F + IPE S V ++ AED D N +I Y++ S +F + P + LDRE S + A D S + V ++D+NDN PQ++ SS + I+ + VG + A+D+D G N ++Y + + + +LF+L++ SG+L + + +I L + D G L+ +
Sbjct: 256 VVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEI-EYSLGEGNGKNL----LAINA-------KSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGI---GGLTIDYSTGEVTLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLI------AAQKMITLEENVAIGEEVGRVYAIDEDS--------GPNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEADREVFSILDIGDQGAIL--SVSGELKRQ----DHKVRVEISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHD-RGDNARIVYSI----------DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSS---YAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAAS 876 HSP 3 Score: 117.472 bits (293), Expect = 3.933e-26 Identity = 152/591 (25.72%), Postives = 254/591 (42.98%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYI--NGKNGKIF--VKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGG--LKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH-------FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHS------FSIEAWDSGPITHRVSVDVVVKIEDLNDNFP 2255
+ I++ DINDH+P ++ +I + E+ IG A D DS P N I +Y+++ + F I +S L++ +DRE + L + A D G+P L ST + + + DINDN+P F K ++I E + + A D D ++ K+T+ + DR F I G G I ++ D +V + I TD ++ ++ ++AP + P + + E+ + +L A D D S ++ D+SV + LDRE F + D PP T+ I + + D ND +P F ++ I E +PV + +++A D D+G N + Y ++ + F +D +G LR +S DRE+ L DR P+ LS+ + I + + D+ND AP F++L Y+ I E S VG+++A D+D E N IS+ + +KL F + D L R +D + F ++A SG ++ +V V + + D+NDN P
Sbjct: 465 LTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGP-NGIIKYSMEGSED-----FIIDEDS---------GLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEA----DREVFSILDIGDQGAILSVSGELKRQDHKVR---VEISATDQGGLQGRCVVNVFIDDVNSAPYFNDHPF------SVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRIDPSSGDISV--------SSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDR-----GTPS---LSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDAD-EGDNADISFRIF------GGADAKL-FDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQA-SSGQLSS--TVPVRIHVSDVNDNKP 998 HSP 4 Score: 116.316 bits (290), Expect = 8.572e-26 Identity = 163/636 (25.63%), Postives = 276/636 (43.40%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD----STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHF-SIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKS 2432
++I++ D+ND++PV+ + I E+ I + A D D + + Y++ ++S + +I Y+ T L R+DA I ++ A+D P L+ + LTIN+ DIND++P + I+++EN I + + +++A D D N + +S +E F I+ +G I ++LD + Y L + D S + TI +V +++ NDNAP NV + EE + + I +L A D D I + V + L + + IL + + + I D G ++N+ + D N P+F +V I E P+ V L A D D G N+++VY ID + F ID ++G + +S DRE + + T SD L+++T I VI+ DIND +P F Y +I E V A D+DI N + Y + E+ S S F + LDRE + + I A D G + + ++ + + D+NDN P + L + I VG V + A D+D G N+ +++ I G + +LF + + +
Sbjct: 361 VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKV-HYSM--ASSSGIGGLTIDYS-----TGEVTLRERIDAK-----NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYS------MEGSEDFIIDEDSGLIKTTKLLDRETTAR-YSLKVTARDMGTPSLNTSTTIAVV-LKDINDNAPTFD-----KKEYNVTISEE-MPRGSQIITLKAVDNDEDQKITYRIEEAD----REVFSILDIGDQGAILSVSGELKRQDHKVRVEISATDQGGLQGRC--VVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTA--------SDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADI-GPNGIVDYFL----NESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQ---LSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDA 946 HSP 5 Score: 92.4337 bits (228), Expect = 1.840e-18 Identity = 82/339 (24.19%), Postives = 161/339 (47.49%), Query Frame = 3
Query: 276 QVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNF-VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSN-----YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFS-FGNS----MNIEDRSKFYINGKNG--KIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVI 1253
++ EHS IG + L + +D D + + + F + +G + V +D+DRE T F ++ ++ +I++ ++DIND+SP +T S I E +G+ + A D D P+ + + + ++ ++LF + D+T LRV + +DRE+ I L + A D G+P L+ ++ +T+ ++D+NDN+P F + ++ I EN+ + + + A+D D DN ++F FG + +IE+ ++ +NG +I + DY+ + N + +Q + + + + V + NDN P +
Sbjct: 690 KIPEHSPIGYPVITL----KAEDHDRGDNARIVYSIDSSQFFRIDPSSGDISVSSDLDREDRAT----------FSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRL------DRT---SGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAE-----QNGVVRILTRAEFDYEAKANKFFFELQASSGQLSSTVPVRIHVSDVNDNKPAL 1000 HSP 6 Score: 92.0485 bits (227), Expect = 2.411e-18 Identity = 106/429 (24.71%), Postives = 185/429 (43.12%), Query Frame = 3
Query: 1086 FYINGKNGKIFVKQILDYDQEVNTYLLPI---QVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTK-PLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRN------LVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKA 2342
F ++ +G+I + + +D + ++ ++L + + D T A T ++V V + DN+P+ + + E+ T + S+ A D+D+ S G + L++ K ++ T PLDRET + + D G P + +T ++ I V+D ND P F + V I E + + + + + A+D D G N ++ H+S+ ++G+ + TGE L + D +N + D + LSST + + + DIND AP ++ E + VG V A D D N I Y+M F + D + T + LDRET +S + A D G + S + V ++D+NDN P + ++ I+ E G + LKA
Sbjct: 213 FTLDTMSGEIRLAKSMDR-EVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGE------IREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNL----LAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKV-------HYSMASSSGI---GGLTIDYSTGEVTLRERI-DAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDED-SGPNGIIKYSME----------GSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKE---YNVTISEEMPRGSQIITLKA 605 HSP 7 Score: 78.9518 bits (193), Expect = 2.116e-14 Identity = 121/481 (25.16%), Postives = 204/481 (42.41%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFY-INGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD---NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENT---GVLR--TNSIFDREKTGE---YKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFK 1925
I + ++DIND++P + + + + I E GS+ + K +D+ D I+ + + ++FSI+ + D+ +L V + R+ + + + G L G + + I D+N ++P F + I E++ I + + A+D D DN ++ +S D S+F+ I+ +G I V LD + T+ + + +D T + V + + NDN+P SS+ + E+I T+ +SA D D N SS + D T T+ ++ LDRE I +D G P I + + D ND P F +YI E PV S V + A D D G N+ + +RI D F I+E+ GV+R T + FD E ++L+A + LSST +R+ + D+ND P K
Sbjct: 567 IAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQ--IITLKAVDNDEDQKITYR----IEEADREVFSIL--DIGDQG----AILSVSGELKRQDHKVRVEISATDQGG---LQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI-------DSSQFFRIDPSSGDISVSSDLDREDRA-TFSVIVTASDHASPPLNTSTQIEVILDDINDNSP------QFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDR---TSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQA-------------SSGQLSSTVPVRIHVSDVNDNKPALK 1001
BLAST of Protocadherin vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 116.316 bits (290), Expect = 7.380e-26 Identity = 152/591 (25.72%), Postives = 254/591 (42.98%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYIN--GKNGKIFV--KQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGG--LKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH-------FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHS------FSIEAWDSGPITHRVSVDVVVKIEDLNDNFP 2255
+ I++ DINDH+P ++ +I + E+ IG A D DS P N I +Y+++ + F I +S L++ +DRE + L + A D G+P L ST + + + DINDN+P F K ++I E + + A D D ++ K+T+ + DR F I G G I ++ D +V + I TD ++ ++ ++AP + P + + E+ + +L A D D S ++ D+SV + LDRE F + D PP T+ I + + D ND +P F ++ I E +PV + +++A D D+G N + Y ++ + F +D +G LR +S DRE+ L DR P+ LS+ + I + + D+ND AP F++L Y+ I E S VG+++A D+D E N IS+ + +KL F + D L R +D + F ++A SG ++ +V V + + D+NDN P
Sbjct: 106 LTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGP-NGIIKYSMEGSED-----FIIDEDSG---------LIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDND--EDQKITYRIEEA----DREVFSILDIGDQGAILSVSGELKRQDHKVR---VEISATDQGGLQGRCVVNVFIDDVNSAPYFNDHPFS------VKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRIDPSSGDISV--------SSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDR-----GTPS---LSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDAD-EGDNADISFRIF------GGADAKL-FDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQA-SSGQLSS--TVPVRIHVSDVNDNKP 639 HSP 2 Score: 114.775 bits (286), Expect = 2.220e-25 Identity = 165/637 (25.90%), Postives = 281/637 (44.11%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD----STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTIL-LTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH-FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKS 2432
++I++ D+ND++PV+ + I E+ I + A D D + + Y++ ++S + +I Y+ T L R+DA I ++ A+D P L+ + LTIN+ DIND++P + I+++EN I + + +++A D D N + +S +E F I+ +G I ++LD + Y L + D S + TI +V +++ NDNAP NV + EE + + I +L A D D I + V + L + + IL ++ L R+ ++ + I D G ++N+ + D N P+F +V I E P+ V L A D D G N+++VY ID + F ID ++G + +S DRE + + T SD L+++T I VI+ DIND +P F Y +I E V A D+DI N + Y + E+ S S F + LDRE + + I A D G + + ++ + + D+NDN P + L + I VG V + A D+D G N+ +++ I G + +LF + + +
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKV-HYSM--ASSSGIGGLTIDYS-----TGEVTLRERIDAK-----NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYS------MEGSEDFIIDEDSGLIKTTKLLDRETTAR-YSLKVTARDMGTPSLNTSTTIAVV-LKDINDNAPTFD-----KKEYNVTISEE-MPRGSQIITLKAVDNDEDQKITYRIEEAD----REVFSILDIGDQGAILSVSGELKRQDHK-VRVEISATDQGGLQGRC--VVNVFIDDVNS-APYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTA--------SDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADI-GPNGIVDYFL----NESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQ---LSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDA 587 HSP 3 Score: 92.0485 bits (227), Expect = 2.170e-18 Identity = 82/339 (24.19%), Postives = 161/339 (47.49%), Query Frame = 3
Query: 276 QVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNF-VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSN-----YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFS-FGNS----MNIEDRSKFYINGKNG--KIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVI 1253
++ EHS IG + L + +D D + + + F + +G + V +D+DRE T F ++ ++ +I++ ++DIND+SP +T S I E +G+ + A D D P+ + + + ++ ++LF + D+T LRV + +DRE+ I L + A D G+P L+ ++ +T+ ++D+NDN+P F + ++ I EN+ + + + A+D D DN ++F FG + +IE+ ++ +NG +I + DY+ + N + +Q + + + + V + NDN P +
Sbjct: 331 KIPEHSPIGYPVITL----KAEDHDRGDNARIVYSIDSSQFFRIDPSSGDISVSSDLDREDRAT----------FSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRL------DRT---SGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAE-----QNGVVRILTRAEFDYEAKANKFFFELQASSGQLSSTVPVRIHVSDVNDNKPAL 641 HSP 4 Score: 77.7962 bits (190), Expect = 4.096e-14 Identity = 121/481 (25.16%), Postives = 204/481 (42.41%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFY-INGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD---NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENT---GVLR--TNSIFDREKTGE---YKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFK 1925
I + ++DIND++P + + + + I E GS+ + K +D+ D I+ + + ++FSI+ + D+ +L V + R+ + + + G L G + + I D+N ++P F + I E++ I + + A+D D DN ++ +S D S+F+ I+ +G I V LD + T+ + + +D T + V + + NDN+P SS+ + E+I T+ +SA D D N SS + D T T+ ++ LDRE I +D G P I + + D ND P F +YI E PV S V + A D D G N+ + +RI D F I+E+ GV+R T + FD E ++L+A + LSST +R+ + D+ND P K
Sbjct: 208 IAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQ--IITLKAVDNDEDQKITYR----IEEADREVFSIL--DIGDQ----GAILSVSGELKRQDHKVRVEISATDQGG---LQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI-------DSSQFFRIDPSSGDISVSSDLDREDRA-TFSVIVTASDHASPPLNTSTQIEVILDDINDNSP------QFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDR---TSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQA-------------SSGQLSSTVPVRIHVSDVNDNKPALK 642
BLAST of Protocadherin vs. Ensembl Celegans
Match: cdh-3 (Cadherin-3 [Source:UniProtKB/Swiss-Prot;Acc:P34616]) HSP 1 Score: 115.931 bits (289), Expect = 1.127e-25 Identity = 196/770 (25.45%), Postives = 344/770 (44.68%), Query Frame = 3
Query: 264 SLQFQVKE----HSEIG--LLIGDLVEN--YRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPL------AKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPA---AITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGE---YKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG 2513
+ +F + E +E+G +++G +E +RIQD D NF +S +G +F + +D E I T + +N+ + ++ I + D ND +P + +V N+ ++ + Y PL A+DLD N + Y++ N S LF++ + T + L L +DRE+ ELL+ A+D+G P L+ ++ + I++ DINDN+P F I I EN+ I + ++ A D D + +L +S N E F IN G I V ++ +E + ++VTD K ++ I+ + V++ NDN P+I N N+ + V + + I ++ D+D S LK S ++L++ I L PL +T + T+ D G+ + ++ L HFP + TV + E E V K N + S+ H ++++TG+L+T S D E+ E + + T +D K LS+ T + I DIND +P F + Y F++ E S P++ +G V+A DI+ +R YE + F V+ G+I + ++ LDRET + +EA D G R + V+V + D +DN P++S + + + +G V L A SD+ +S+ +E+ G E F++++ +G +++ + R+ VK++D
Sbjct: 1559 TFEFNISETADRFTEVGKIVILGAGLEGSVFRIQDNDY------NFT-------ISPFDGTIFTNSPLDFENIKTYR------------FNITAGKSTSQVIIHVTDENDEAPRFITGDVV-NLKVLEELDTVSY-PLIIGSSIAEDLDEG-QNGLVTYSILSGNTS---LFAV------NSTTGDILSL---IPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKD--KDAELQYSL--ESNDEITIPFRINVATGWITVAGKVNR-EENEEFRFFVKVTDGEKSSKVIVEIHVEDFNDNHPMI------NDRNSDIFVPDPTRSVEIIHVINVHDLDKSDH----------LKFSLNNSNLNLSENGEITLKSPL--QTAVPVRVTV-SDDAGH-------VAFMEYLFHPHSRKHFPVFVEKLDTVSVREHDEQELAVFKANGDSIRYSIVSRC-----SDHLEMEKSTGILKTKSSLDAEEYSECLVFIIATTYFDN----------KPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSGPKL-IGHVIAR--DIDRSSRVF--------YEIVGGDANHEFMVTESGQIESVRD-LDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRI----FHVEVPEDVRIGEPVIQLSA--SDADEHSNHRFELDGGGEGIPFRVDENTGMVFVNDSLDFEKKQSYRIKVKLTDGA 2224 HSP 2 Score: 79.337 bits (194), Expect = 1.547e-14 Identity = 65/203 (32.02%), Postives = 100/203 (49.26%), Query Frame = 3
Query: 1461 KPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPY 2057
+ LDRET + ++ DDG P + + + VLD++D P F + I V + E V + V +L+ASD D N + + +D F +DENTG++ N D EK Y+++ + D L++ T + V +KD+ND AP+F+K Y F E S+ +G A D D E N +I Y+ V PY
Sbjct: 2102 RDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRF-SRIFHVEVPEDVRIGEPVIQLSASDADEHSNHR--FELDGGGEGIPFRVDENTGMVFVNDSLDFEKKQSYRIKVKLTDGAWLIE-----------TSLFVNVKDVNDNAPIFEKPEYLFISEENSAE---IGQFHASDMDSEN-NGKIRYS-VTSPY 2285 HSP 3 Score: 72.7886 bits (177), Expect = 1.587e-12 Identity = 80/317 (25.24%), Postives = 140/317 (44.16%), Query Frame = 3
Query: 417 GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSK---IGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDN 1358
G L K+ +D E + ++C + ++ K S + I I DIND+SP + Q N+ E+S IG +A+D+D S SR + V F + + + ++DRE + L++ A D G P G+T + + + D +DN+P F + + + + E+ I + + Q+ A D D N + G + F ++ G +FV LD++++ +Y + +++TD ET L V V++ NDNAP+ + + EEN I A+DMD+
Sbjct: 1994 GILKTKSSLDAE----EYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSGPKLIGH----VIARDIDRS-----SRVFYEIVGGDANHEFMVTESGQIESV----------RDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSR-IFHVEVPEDVRIGEPVIQLSASDADEHSNHRFELDGGG-----EGIPFRVDENTGMVFVNDSLDFEKK-QSYRIKVKLTDGAWLIETSLFVNVKDVNDNAPIFE------KPEYLFISEEN---SAEIGQFHASDMDS 2271 HSP 4 Score: 72.4034 bits (176), Expect = 2.420e-12 Identity = 84/299 (28.09%), Postives = 138/299 (46.15%), Query Frame = 3
Query: 870 PLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT-YLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVL 1754
PL+ T TI I DINDNSP F + L ++ EN+ + + + A+D+D S G D + ++ ++G+I + + D D+E + Y L ++ D K T ++V V +E+DNAP S + HV +V + E IQ LSA+D D S G RV + +V + LD E + ++ +K D + + T+ +N++ D ND P F ++I E E + + +ASD D N ++ Y + +F I+ +TGVL
Sbjct: 2024 PLSTITKATIKIVDINDNSPRFDQQLYRFNVTENSG-PKLIGHVIARDIDRSSRVFYEIVGG------DANHEFMVTESGQI--ESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRIFHVEVPEDVRIGEPVIQ-------LSASDADEHSNHRFELDGGGEGIPFRVDENTGMV-----FVNDSLDFEKKQSYRIKVKLTDGAWLIE-TSLFVNVK--DVNDNAPIFEKP-EYLFISEENSAE--IGQFHASDMDSENNGKIRYSVTSPYFKIEPSTGVL 2295 HSP 5 Score: 67.781 bits (164), Expect = 5.037e-11 Identity = 55/171 (32.16%), Postives = 81/171 (47.37%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTL--KYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTF 1046
I I + D+ND+SP++ + IPE + IG R + A D D + +I +Y L + F IV + L L V +DRE + + L A D G P L+ S HL I I DINDN P F + +++ N + L + A DLD ++N LT+
Sbjct: 103 ILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSD-------GFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNF--GIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTY 264
BLAST of Protocadherin vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 115.161 bits (287), Expect = 2.233e-25 Identity = 170/724 (23.48%), Postives = 290/724 (40.06%), Query Frame = 3
Query: 456 ICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPL-----AKDLDSSPDNSISRYTLKYVNNSQLKLFSI-----VYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSK----FY--INGKNGKI-FVKQILDYDQEVNTYLLPIQVTDSTKFAETI-----LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSA-TDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT-------ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNA----------SDCDVGVNSQLVYRI-------DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTI-IRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVG---RLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDP 2474
+ + + CC VY K ++Y + I IED+N++ P + +I + + + P A D DSS + I Y+L Y + K F I V P + + R D + A D G PL G ++ + DINDNSP F +P E S+ + + +FA D D + N ++T+S + + F+ +N ++G+I +K I + ++ + + D E + + + V ++ AP P + V+EN++ I A + D+ ++ + ++ G ++ + K+ +++ + LD E + T+ D +TK ++V D ND P F + T IDE + + K N +D D G +++ YRI + HF IDE TG + N FDREK Y L DR V + P + + ++++I D+ND AP F++ Y + E V ++ A D D + + Y ++ + ++ F V D KE LD E D + + A D H + +V + IED+NDN PQ+ I EE V L V +S + Y + E+F++ + SG++ L+K L DP
Sbjct: 829 VIVQDDGSCC------VYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIV-YSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTV------------KATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPI---PMKTQKFIFNV-IADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPG---ITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD-MTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSD-GPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRS--VSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHS---NLRYHLI------GAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG---RHNATTNVYIHIEDVNDNAPQFEQQKYATTVI----EEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVK-ALDRDP 1505 HSP 2 Score: 98.5969 bits (244), Expect = 2.204e-20 Identity = 134/526 (25.48%), Postives = 218/526 (41.44%), Query Frame = 3
Query: 891 LTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLL------------PIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQA------TIKCQDDG----YPPQVTTKIIN--IQVLDKNDCTPHFPAAITTVYIDEGVPVES-------FVTKLNASDCDVGVNSQLVYRIDHAH------FSIDENTGVLRTNS--IFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFS--VSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKA 2342
LTI I D+NDN P F +PL ++E+ ++Q + ++ A D D DN ++T+S D F IN NG+I K LD DQ + + P+ ++ S ++ ++ +N ND + V LP +S V E+ Q T + + A D D S +G S +L + ++T L+ + +A T+ QDDG YP + T I + D N+ P FP Y D +E + K+ A+D D N +VY + + F ID TGVL + +FDRE + DR ++ L V + DIND +P F++ YE S+ + V +V A D+D A N +I+Y++ I + H + L F V+ T + + +T F++ A D+G P + S V + + D P+W S D I + + +++ +A
Sbjct: 628 LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSV-------DNHNFSIN-SNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSS-----AMIHIRTENTNDESAV--FLP---TSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNG---RSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAK--YSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDR--------GDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDA-AHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKF-IFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRA 1120 HSP 3 Score: 93.2041 bits (230), Expect = 9.626e-19 Identity = 150/629 (23.85%), Postives = 250/629 (39.75%), Query Frame = 3
Query: 546 ISIEDINDHSPVWTQSKIVINIPEH-------SKIGSRYYLPL-AKDLDS-SPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKY--TILLTKPLDRETNEF---FQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGV-PVES---FVTKLNASDCD--VGVNSQLVYRI-------DHAHFSIDENTGVLRTNSIFDREKTGE--YKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGR-----IFTTKESLDRE---TYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGR 2321
+ + D+ND P +T I E K + + + A D DS P N + + N + K F I + L + + N+ R ++ +E + + A + P + + I I D+NDN+P F + +KE+ + + A DLD N + I F + +G IFVK+ LD++ + Y L + +D A T + + +++ NDNAP + + ++EE++ + ++ ATD D G V + KY TI L K LDR+ + ++ DD V + + V D ND +P FP + YI+E P+ S + + A D D N+ + Y I + F ID+NTG + DRE + E + +E DR P+ + ++ TI + D+ND AP F+K YE S+ E + V S A D+D EA + +Y + Y + D + + K+ LD E D I D H V V + D ND+ P +++ + ++ R ++GR
Sbjct: 1199 VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRI--DELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGGRI----PFGVRTDSGTIFVKEPLDFEAS-DQYHLVLIASDGRHNATTNVYIHIEDVNDNAPQFEQQKYATT-----VIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFR----IGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFG-YIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDR-----GVPSREGFANVTIK---VTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQL-------SEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDG---RHDAEAAVHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGR 1792 HSP 4 Score: 89.3521 bits (220), Expect = 1.412e-17 Identity = 169/713 (23.70%), Postives = 286/713 (40.11%), Query Frame = 3
Query: 336 IQDFDLSRRENLNFQMMKENNF-----VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVIN-IPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKEN----NFIDQYLCQMFAKDLDISDNDKLTFSFGNSMN--IEDRSKFYINGKNGKIFVKQILDYDQEVNT---YLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSR------VLTDL-SVVTKYTILLTK-PLDRE---TNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA-----HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIP-----EGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGR----IFTTKESLDRET---YDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINI----TREETVGRL 2324
I+ DL + NL + ++ V +G +FVK +D E +Q +L +I + + + + I IED+ND++P + Q K I E I + A D D D SR + ++F I S +L+ +D + ++ +D G+ L G + +N+ DINDNSP+F + L I+EN + Y + A+D D + +G N I S F I+ GKIF + L D+E+++ +++ ++ D ++ + +KV + NDNAP + S VEE A+ S SA D D + +LS V TD S + +L K PLD E + F I+ D + + +++ ++D+ND PH A T + E VP + + + A+D D G ++ +RI+ F+ID++ G LR DRE Y L YD N + ++ V ++D+ND P +++P ++P +G+ +D + + M + P S + F+ + DG T + DRE + + D + SV V+ I DLNDN H + + +N +E +GR+
Sbjct: 1357 IKAHDLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFE----ASDQ---YHLVLIASDGRHNATT-NVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQ--DEKSSRIVYRLEGQGADEVFRIGKYS-----GTIELVKALDRDPPAGVPSWNFVVQAIDDDGN-GLVGYADVQVNVRDINDNSPIFPERLFGY-IEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSL--DREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGS------VEETAPIGAAVMSFSAFDADEEAKDNVFT-----YQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAA---VHVALVDRNDHAPHIHGA-TEHRVREDVPRGTSIGRYTATDRDAGDTAR--FRINRQSDPKRQFTIDQD-GTLRVAHTLDREDIAVYNLIIEAYDNSNNI----------GRQMVAVYLQDVNDNGP------EPYTVPRPCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGSMTITPLQEFDREAPVPGKILEIPLILADRAGRRNEASVHVI--IGDLNDNT---MHDGRMTIHVNSYLGRLKETVIGRV 2011 HSP 5 Score: 60.8474 bits (146), Expect = 7.569e-9 Identity = 144/604 (23.84%), Postives = 255/604 (42.22%), Query Frame = 3
Query: 915 NDNSPVFLKPLTEISIKENNFIDQYL----CQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVT--DSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLD----RETNEFFQATIKCQDDGYPPQV-TTKIINIQVLDKNDCTPHF-PAAITTVYIDEGVPVESFVTKLNASDCD--------VGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYK--LEATVYDRRNLVDSDPT-----EKVLSSTTIIRVIIKDINDCAPVF---KKLFYEFSIPEG---SSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESL--DRETYDMHSFSIEAWDSG--PITH--RVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI----IQGNEHE----LFKL-NQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVSKLP 2579
++ P F K E+++ E+N +D + Q F D +T+S ++ F I+ G I + ++LD+D L ++VT + + + L +++ + NDN P + P + V E+I I ++A D D + S + S+ + I LD E + ++ + +D G P + ++ +I+I+ + ND + F P + T ++ E + V ++ A D D + N + +++ FSIDE+TG+++ E + + TV +V D + K +S + + I+D+N+ P F K I EG + P V V A D D A N I Y++ Y T+S S+ F + + T + DRET +++A D G P+ + SV+VV D+NDN PQ+ S +++R E VG V + A D+D+ N+ + Y + G EH+ F+L N++SG + L+K P+ + V D+G P L ++ V + + K P
Sbjct: 524 DERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTFT-RPLYTAQ-----VREDIPLNQTILKVTAVDKDTGDNSR--------ITYSVDNHNFSINSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNGRSTQKMN--LFSIDEHTGLVKLRHGVSAADLAEAENPINLTV-----IVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIV-KVEATDDDSSA-NGDIVYSL----YYTQSE-SRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVV----DINDNSPQFERPS---YETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIK-PIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAP 1091 HSP 6 Score: 60.4622 bits (145), Expect = 9.189e-9 Identity = 166/730 (22.74%), Postives = 309/730 (42.33%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSP-PLTGSTHLTINITDINDNSPVFLKPLTEIS--IKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQ---ILDYDQEVNTYLLPIQVTD---------STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENI--QDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKP----LDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF--PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRN------LVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSH--ISKLYFSVSPDGRI------------------FTTKESLDRETYDMHSFSIEAWDSGPITHRVSV--DVVVKIEDLNDNFPQ-----WSHSSDLGLSINITREETVGRLVTVLKAXXXXXXX-XXXXXYEII---QGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPL 2525
+ ++ ++ I I+D+ND+ P +T+ + E + A D D+ DNS Y++ N FSI N +R+DA+ E+ + A D G P L+ S + I + ND S VFL P ++ + + E+ + Q+ A+D +D D++T+SF N + + + F I+ G + ++ D + N L + V D T + LL+ +++ N+N P P +++ + E D I + ATD D+S+ S SR V+ + T +LT DRET T+K D G P + +++V+D ND +P F P+ T+V E V V + A D D N+++ Y ++ + +E+ L + +R ++GE L + + + D + + L S+ + + + D AP ++ +SP G + D ++E +N+ I + ++++ I KL S P + E LD E + ++ ++ A D +T RV+ VV++ D+ND PQ ++ + D ++ N E+T G+ + +KA+D+DS + ++Y I+ G E + F++++ +G ++ ++ ++ L V+ SD S L
Sbjct: 622 RESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTG-DNSRITYSVDNHN------FSINSNGEISAK------VRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFL-PTSQYTAFVAEDAQGGTPVIQIQARD---ADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPE---FPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESR---KAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTS--VITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNR-RSGEITLIKPIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQ-----------TSPDCKPG--ITVDENVE-LNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD---MTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSAL 1308
BLAST of Protocadherin vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 115.161 bits (287), Expect = 2.233e-25 Identity = 170/724 (23.48%), Postives = 290/724 (40.06%), Query Frame = 3
Query: 456 ICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPL-----AKDLDSSPDNSISRYTLKYVNNSQLKLFSI-----VYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSK----FY--INGKNGKI-FVKQILDYDQEVNTYLLPIQVTDSTKFAETI-----LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSA-TDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT-------ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNA----------SDCDVGVNSQLVYRI-------DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTI-IRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVG---RLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDP 2474
+ + + CC VY K ++Y + I IED+N++ P + +I + + + P A D DSS + I Y+L Y + K F I V P + + R D + A D G PL G ++ + DINDNSP F +P E S+ + + +FA D D + N ++T+S + + F+ +N ++G+I +K I + ++ + + D E + + + V ++ AP P + V+EN++ I A + D+ ++ + ++ G ++ + K+ +++ + LD E + T+ D +TK ++V D ND P F + T IDE + + K N +D D G +++ YRI + HF IDE TG + N FDREK Y L DR V + P + + ++++I D+ND AP F++ Y + E V ++ A D D + + Y ++ + ++ F V D KE LD E D + + A D H + +V + IED+NDN PQ+ I EE V L V +S + Y + E+F++ + SG++ L+K L DP
Sbjct: 829 VIVQDDGSCC------VYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIV-YSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTV------------KATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPI---PMKTQKFIFNV-IADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPG---ITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD-MTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSD-GPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRS--VSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHS---NLRYHLI------GAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG---RHNATTNVYIHIEDVNDNAPQFEQQKYATTVI----EEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVK-ALDRDP 1505 HSP 2 Score: 98.5969 bits (244), Expect = 2.204e-20 Identity = 134/526 (25.48%), Postives = 218/526 (41.44%), Query Frame = 3
Query: 891 LTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLL------------PIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQA------TIKCQDDG----YPPQVTTKIIN--IQVLDKNDCTPHFPAAITTVYIDEGVPVES-------FVTKLNASDCDVGVNSQLVYRIDHAH------FSIDENTGVLRTNS--IFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFS--VSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKA 2342
LTI I D+NDN P F +PL ++E+ ++Q + ++ A D D DN ++T+S D F IN NG+I K LD DQ + + P+ ++ S ++ ++ +N ND + V LP +S V E+ Q T + + A D D S +G S +L + ++T L+ + +A T+ QDDG YP + T I + D N+ P FP Y D +E + K+ A+D D N +VY + + F ID TGVL + +FDRE + DR ++ L V + DIND +P F++ YE S+ + V +V A D+D A N +I+Y++ I + H + L F V+ T + + +T F++ A D+G P + S V + + D P+W S D I + + +++ +A
Sbjct: 628 LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSV-------DNHNFSIN-SNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSS-----AMIHIRTENTNDESAV--FLP---TSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNG---RSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAK--YSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDR--------GDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDA-AHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKF-IFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRA 1120 HSP 3 Score: 93.2041 bits (230), Expect = 9.626e-19 Identity = 150/629 (23.85%), Postives = 250/629 (39.75%), Query Frame = 3
Query: 546 ISIEDINDHSPVWTQSKIVINIPEH-------SKIGSRYYLPL-AKDLDS-SPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKY--TILLTKPLDRETNEF---FQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGV-PVES---FVTKLNASDCD--VGVNSQLVYRI-------DHAHFSIDENTGVLRTNSIFDREKTGE--YKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGR-----IFTTKESLDRE---TYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGR 2321
+ + D+ND P +T I E K + + + A D DS P N + + N + K F I + L + + N+ R ++ +E + + A + P + + I I D+NDN+P F + +KE+ + + A DLD N + I F + +G IFVK+ LD++ + Y L + +D A T + + +++ NDNAP + + ++EE++ + ++ ATD D G V + KY TI L K LDR+ + ++ DD V + + V D ND +P FP + YI+E P+ S + + A D D N+ + Y I + F ID+NTG + DRE + E + +E DR P+ + ++ TI + D+ND AP F+K YE S+ E + V S A D+D EA + +Y + Y + D + + K+ LD E D I D H V V + D ND+ P +++ + ++ R ++GR
Sbjct: 1199 VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRI--DELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGGRI----PFGVRTDSGTIFVKEPLDFEAS-DQYHLVLIASDGRHNATTNVYIHIEDVNDNAPQFEQQKYATT-----VIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFR----IGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFG-YIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDR-----GVPSREGFANVTIK---VTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQL-------SEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDG---RHDAEAAVHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGR 1792 HSP 4 Score: 89.3521 bits (220), Expect = 1.412e-17 Identity = 169/713 (23.70%), Postives = 286/713 (40.11%), Query Frame = 3
Query: 336 IQDFDLSRRENLNFQMMKENNF-----VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVIN-IPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKEN----NFIDQYLCQMFAKDLDISDNDKLTFSFGNSMN--IEDRSKFYINGKNGKIFVKQILDYDQEVNT---YLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSR------VLTDL-SVVTKYTILLTK-PLDRE---TNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA-----HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIP-----EGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGR----IFTTKESLDRET---YDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINI----TREETVGRL 2324
I+ DL + NL + ++ V +G +FVK +D E +Q +L +I + + + + I IED+ND++P + Q K I E I + A D D D SR + ++F I S +L+ +D + ++ +D G+ L G + +N+ DINDNSP+F + L I+EN + Y + A+D D + +G N I S F I+ GKIF + L D+E+++ +++ ++ D ++ + +KV + NDNAP + S VEE A+ S SA D D + +LS V TD S + +L K PLD E + F I+ D + + +++ ++D+ND PH A T + E VP + + + A+D D G ++ +RI+ F+ID++ G LR DRE Y L YD N + ++ V ++D+ND P +++P ++P +G+ +D + + M + P S + F+ + DG T + DRE + + D + SV V+ I DLNDN H + + +N +E +GR+
Sbjct: 1357 IKAHDLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFE----ASDQ---YHLVLIASDGRHNATT-NVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQ--DEKSSRIVYRLEGQGADEVFRIGKYS-----GTIELVKALDRDPPAGVPSWNFVVQAIDDDGN-GLVGYADVQVNVRDINDNSPIFPERLFGY-IEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSL--DREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGS------VEETAPIGAAVMSFSAFDADEEAKDNVFT-----YQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAA---VHVALVDRNDHAPHIHGA-TEHRVREDVPRGTSIGRYTATDRDAGDTAR--FRINRQSDPKRQFTIDQD-GTLRVAHTLDREDIAVYNLIIEAYDNSNNI----------GRQMVAVYLQDVNDNGP------EPYTVPRPCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGSMTITPLQEFDREAPVPGKILEIPLILADRAGRRNEASVHVI--IGDLNDNT---MHDGRMTIHVNSYLGRLKETVIGRV 2011 HSP 5 Score: 60.8474 bits (146), Expect = 7.569e-9 Identity = 144/604 (23.84%), Postives = 255/604 (42.22%), Query Frame = 3
Query: 915 NDNSPVFLKPLTEISIKENNFIDQYL----CQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVT--DSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLD----RETNEFFQATIKCQDDGYPPQV-TTKIINIQVLDKNDCTPHF-PAAITTVYIDEGVPVESFVTKLNASDCD--------VGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYK--LEATVYDRRNLVDSDPT-----EKVLSSTTIIRVIIKDINDCAPVF---KKLFYEFSIPEG---SSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESL--DRETYDMHSFSIEAWDSG--PITH--RVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI----IQGNEHE----LFKL-NQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVSKLP 2579
++ P F K E+++ E+N +D + Q F D +T+S ++ F I+ G I + ++LD+D L ++VT + + + L +++ + NDN P + P + V E+I I ++A D D + S + S+ + I LD E + ++ + +D G P + ++ +I+I+ + ND + F P + T ++ E + V ++ A D D + N + +++ FSIDE+TG+++ E + + TV +V D + K +S + + I+D+N+ P F K I EG + P V V A D D A N I Y++ Y T+S S+ F + + T + DRET +++A D G P+ + SV+VV D+NDN PQ+ S +++R E VG V + A D+D+ N+ + Y + G EH+ F+L N++SG + L+K P+ + V D+G P L ++ V + + K P
Sbjct: 524 DERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTFT-RPLYTAQ-----VREDIPLNQTILKVTAVDKDTGDNSR--------ITYSVDNHNFSINSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNGRSTQKMN--LFSIDEHTGLVKLRHGVSAADLAEAENPINLTV-----IVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIV-KVEATDDDSSA-NGDIVYSL----YYTQSE-SRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVV----DINDNSPQFERPS---YETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIK-PIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAP 1091 HSP 6 Score: 60.4622 bits (145), Expect = 9.189e-9 Identity = 166/730 (22.74%), Postives = 309/730 (42.33%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSP-PLTGSTHLTINITDINDNSPVFLKPLTEIS--IKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQ---ILDYDQEVNTYLLPIQVTD---------STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENI--QDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKP----LDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF--PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRN------LVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSH--ISKLYFSVSPDGRI------------------FTTKESLDRETYDMHSFSIEAWDSGPITHRVSV--DVVVKIEDLNDNFPQ-----WSHSSDLGLSINITREETVGRLVTVLKAXXXXXXX-XXXXXYEII---QGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPL 2525
+ ++ ++ I I+D+ND+ P +T+ + E + A D D+ DNS Y++ N FSI N +R+DA+ E+ + A D G P L+ S + I + ND S VFL P ++ + + E+ + Q+ A+D +D D++T+SF N + + + F I+ G + ++ D + N L + V D T + LL+ +++ N+N P P +++ + E D I + ATD D+S+ S SR V+ + T +LT DRET T+K D G P + +++V+D ND +P F P+ T+V E V V + A D D N+++ Y ++ + +E+ L + +R ++GE L + + + D + + L S+ + + + D AP ++ +SP G + D ++E +N+ I + ++++ I KL S P + E LD E + ++ ++ A D +T RV+ VV++ D+ND PQ ++ + D ++ N E+T G+ + +KA+D+DS + ++Y I+ G E + F++++ +G ++ ++ ++ L V+ SD S L
Sbjct: 622 RESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTG-DNSRITYSVDNHN------FSINSNGEISAK------VRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFL-PTSQYTAFVAEDAQGGTPVIQIQARD---ADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPE---FPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESR---KAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTS--VITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNR-RSGEITLIKPIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQ-----------TSPDCKPG--ITVDENVE-LNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD---MTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSAL 1308
BLAST of Protocadherin vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 186.037 bits (471), Expect = 4.671e-47 Identity = 193/715 (26.99%), Postives = 317/715 (44.34%), Query Frame = 3
Query: 513 LKIQSNY-FEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVN-NSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS-TKFAE----------TILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVDVVVKIEDLNDNFPQWSHS------SDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSN---DPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKL 2576
L Q Y E++I + D+ND+SP + + I I+ E + G+R L A D D + +Y + N +++ +L + N D +YL+ L N+DRE +L + A D GSPP G + + I D+NDN P+F +S+ E + + A D D+ DN K+T+ E +F +N + G I + ++ Q+ N Q + T FA T + V + + ND+ P+IS V V+EN + T +A+++ D D+ + G +L + + + + LDRE + T+ D G P + TT + I V D ND P F + + + E P SFV + A+D D GVN+Q+ Y I + FS+D TG++ T DRE +L + D P K + T ++VII D ND AP F + ++ E + P+ V + A D D + N +++A+ + + L F++ TT+ LDRE + S+ A D G P + V + + D+NDN PQ+ +D I + +E R++ + A D D G N+ + Y + G E LF+L+ +SG++ L ++ P +L+V D+G IV I S++ L
Sbjct: 132 LSSQPTYPIEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTA-NPSGDTSYLH---LETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLA-----ETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFR-FFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLE-EAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISAR------DGGPNPKF--AYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHD-QGTNGSVTFALA----PSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGEG-LFQLDARSGAISLRGDAPASMHWKPH-YKLLVSARDAGQRRSQQDAIVEIVLKSKLEML 820 HSP 2 Score: 167.933 bits (424), Expect = 1.907e-41 Identity = 185/687 (26.93%), Postives = 304/687 (44.25%), Query Frame = 3
Query: 552 IEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEV-----------------------NTYLLPIQVTDST--KFAETI-LLVKVQNENDNAPVISILP-HVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYP-PQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVD--VVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSD 2507
I D+NDH+PV+ + ++PE +K+ +R++ A D+D DN R + + + + ++F + PD L V A +DRE+ + L + D+G P + + I++ D NDN+P F SI EN D ++ ++ A D DI N +L+F+ S +D F I+ +NG F+K + +D+E N LL V+D+ + + + + V V + NDNAP P HV + E + T I + D D S + G + + D + + L + LDRE+ E + +D P + I I VLD+ND P F + + V + E P + + + ASD D GVNSQ+V+ I + F ID TG L + D E Y L N+ SD LS+T + V++ D ND P+F I EG + + +V A+D D +N ++SYA+ + + +F ++ + + T +DRE+ D ++ A D P ++S + V V +ED+NDN P + + L + + V + A D+DS N + YEI+ G + ELFKL + +G + P +L +K +D
Sbjct: 1039 IADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLG-DN--GRISYEIIEGNTERMFGV----FPDG------YLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTL--SSQTQD---FTIDTRNG--FIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVT-------ISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSAT---GQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTL--------NITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPD-SGLNGKVSYAISKQEPQLP---QGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQ-ELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTD 1682 HSP 3 Score: 159.073 bits (401), Expect = 1.166e-38 Identity = 158/589 (26.83%), Postives = 267/589 (45.33%), Query Frame = 3
Query: 879 GSTHLTINITDINDNSPVF-LKPLTE--ISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQE--VNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH--AHFSIDENTGVLRTNSIFDREK---------------------TGEYK-LEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG---PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
G + I I D+NDN+PVF L +E IS+ EN + Q + +D D N ++++S N+ N +F I G +++++ + + ++ L+ ++ L V + + ND+ PV + S + E + T +L+ATD+D G R+ V + + PLDRE +++ T+ C+D G P + + + I V+D+ND P F + T I E P ++FV KL A D D+G N++L + + F+ID G ++T FDRE G Y LEATV SD L ++VI+ D+ND AP F + Y +I EG+S ++ V +D+D E +N + Y++ K + + + S G++ + LDRE+ ++H + A D+ P++ S+ +VV D NDN P+++ SS +++ G + +A D+D G+NS + + I GN + F ++ +GSLYL K D L + SD G L+ T + +
Sbjct: 924 GQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPN----QQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETS------LPETTKVNTRFFALAATDIDLGDNGRISYEIIEG-NTERMF---GVFPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATV--------SDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDAD-EGLNGDVYYSLA------KGNEAGQFNLDSATGQL-SLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVL--DENDNAPEFTQSSS---EVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNV 1477 HSP 4 Score: 154.836 bits (390), Expect = 2.301e-37 Identity = 159/605 (26.28%), Postives = 272/605 (44.96%), Query Frame = 3
Query: 342 DFDLSRRENLNFQMMKENN---FVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKT---YLNQLLLRVDANIDRXXXXXXXXXXXX----------XDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKF---AETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA--------HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFY-----EFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYE 2060
D DL +++++++ N F +G LFV+A +DRE C + +S+ + I + D ND++P +T S +IPE++ + A D D + +S +TL +SQ + F+I + KT + + L++V N + + +A D+G P L + + +TD+NDN+P FL+ ++I E ++ +F +D D N + +S + +F ++ G++ + + LD + + +L+ + + K + + + V +ENDNAP + SS+ V ++E + T + A+D D S S G + D + Y L KPLD E + I D G P TT + N+ V+D ND P FP+ I EG+P+++ + + A D D G+N ++ Y I HF I+ TGV+ T DRE ++L DR + P+E+ LS+ ++ VI++DIND APVF + +FS +GSS V V A+D+D + N ++Y +V P E
Sbjct: 1075 DIDLGDNGRISYEIIEGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDA-----GQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELS-FTL----SSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKG---NEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFT-----QSSSEVSVLETSPTG-TELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLY---LHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDR-----AQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSS--TAVMQVHAKDAD-SSSNGLVTYEIVSGPQE 1649 HSP 5 Score: 130.568 bits (327), Expect = 5.011e-30 Identity = 187/773 (24.19%), Postives = 324/773 (41.91%), Query Frame = 3
Query: 417 GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLF------SIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSK--FYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK--FAETILL-VKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQD--DGYPP--------------------------------QVTTKIINIQVL--DKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH-----------FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG---PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEI-IRLVVKVSDSGPSPLTNTTIVRI 2549
G L A++DRE + + ++ I + +++ ++++++ D ND P + + V N+ E +IG A D D+ + T ++ K ++ N D+ ++ LR+ + + + TI ++D NDN P+F + I EN + Q+ A+D D+ N +L++ + D + F +N + G + + LDY +EV Y+L +Q D+ + + TI + V + NDNAP+ + + + V EN+ T + ++SA D+D+ + + S + G V ++ + + TI + LDRE + T+ +D D + Q + + + +L D ND P F +A T I E V + + V + A D D G N + Y + A FS++ G LR DRE Y L T DR +P + S +IR++ D ND +PVF Y S+ E +S V V A D D E N +I Y++V+ ++H FS+S D + ++L+ E +S ++ A D P + ++ + I D+NDN P + S L + T G ++TV LNS + Y + +G+ +LF++N SG + L+K PL + + L + D+G PLT T IVR+
Sbjct: 1772 GILSTAAELDREAGPEEYE----VEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDT-----LGSVTFLLMDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYT-------------------EAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGV-----VSDWANDVFSLNPQTGMLTLTARLDY-EEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSE------VFENVPIATEVVTVSAKDIDSGNNGLIEYSITAG----DVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETA-IMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDR-----GEPPQST-ESQLLIRIL--DENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVD-EGANGRIRYSIVLG---DQNHD----FSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGD--TAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDS-DLFRINASSGDIALLK-PLDREQQSEYTLTLVAMDTGSPPLTGTGIVRV 2479 HSP 6 Score: 128.257 bits (321), Expect = 3.091e-29 Identity = 185/707 (26.17%), Postives = 306/707 (43.28%), Query Frame = 3
Query: 303 LLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLV---NGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQ--------SNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLN--QLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEIS-IKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD-STKFA------ETILLVKV-------------------QNENDNAPVISILPHVNS------SNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTD---LSV-VTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI---DHAH-FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSP--RMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFP 2255
L IG + R D D ++ F +M ++ L+ GKL + +DRE TK Y L+I+ Y IQ+S D ND+ P++ + +IPE+++ G + +A+D D N+QL + +V + D LN +L + A +D E+++ L++ A+D+G P L+ + + N+ D+NDN+P+F P++ S + EN I + + AKD+D +N + +S + +++ S+F I+ NG I ++ LD + +TY L + D + +FA ET L +K Q + V ++ VN S N + EN+ T + ++ A D D +D S+ T + + LDRE + I +D G PPQ T + I++LD+ND +P F + + E + + V +++A+D D G N ++ Y I D H FSI E+TGV+R + E+ Y L D E T + + I DIND P F Y + E + P YV +V A D+D +N Q+ Y + K S L+ + G I K LDRE ++ ++ A D+G + V V+++D+NDN P
Sbjct: 1836 LQIGHTISTLRAHDPDT--LGSVTFLLMDGHDGKFLLEPSTGKLILNDTLDRE---TKSK-----------YELRIRVSDGVQYTEAYATIQVS--DTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLG-------------QNAQLS-YGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIF-DPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSI-TAGDVD--SEFGID-SNGTIRTRRNLDREHR-STYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDC-------ALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFL-------KEGDSDLFRINASSGDIALLK-PLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDP 2489 HSP 7 Score: 124.405 bits (311), Expect = 4.047e-28 Identity = 154/612 (25.16%), Postives = 263/612 (42.97%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWT---QSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLF---SIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETI---LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT-KPLDRE-----------TNE-------------FFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFP 2255
+ I+I D+ND++PV+ +S+ I++PE++ +G YL +D D+ ++ IS Y+L N Q ++ ++Y P + L+ + L+A D+GSPPL+ L++ I D+ND++PVF E S+ E ++ + A D+D+ DN ++++ GN+ + + +G +FV+ LD +E + Y L + D+ + + + +++ V +ENDNA P +S + EN +T + L+A D D LS D ++ T+ + T +P DRE + E +AT+ D+G P + + V D ND P F A V I EG + +T + D D G+N + Y + + F++D TG L DRE + L D + LSS I +++ D ND AP F + E S+ E S + A D+D + +N Q+ +++ HI + G ++ K LD E ++ +I A D G + +V V + D NDN P
Sbjct: 928 VNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRIS-YSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLI---------------HVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNT------ERMFGVFPDGYLFVRAPLDR-EERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNA------PQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELS------FTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVS--DNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDA-------ALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDAD-QGVNSQVVFSISAGNRRDTFHIDSIT------GSLYLHK-PLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPP 1487 HSP 8 Score: 123.635 bits (309), Expect = 6.443e-28 Identity = 179/656 (27.29%), Postives = 289/656 (44.05%), Query Frame = 3
Query: 537 EIQISIEDINDHSPVWTQSKIVINIPEHS-KIGSRYYLPL-AKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFS-FGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST----KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXG--------GLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFP-AAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA----HFSIDENTGVLRTNS-IFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSL 2441
E+ I+I DIND+ P + S + + E++ Y L + A D D+ P NS RY LK ++ LF I +S D L L DRE+ + L L+A D+GSPPLTG+ + + + DINDN PVF +++EN ++ A D D N KL F+ G M+ +F+I+ + G+I LD +E + Y L + DS+ + + L + V + NDN +P +S+ + V E I + A D+D+ + + SG K V T L + TK TK D T + I D G +++K +L + P F A + + E V +TK++A+ G+ ++ Y I +D N+G+L D E T Y++ + +D L S T+I + + D ND APV ++L Y + E SP + V A D D N + Y + T F ++ G I+ T+ LDRE ++F +EA D G + V++ + D NDN P+++ S+N+T +G V + + D D G N++ +Y + N E F++ +SG++
Sbjct: 2369 ELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDS---DLFRINASS-GDIALLKPL--------DREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMH-----RFHIDSETGEISTATTLDR-EETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDN------IPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTK-----TKSHDDLT---YTIVISAMDQG-EQSLSSKAELTVILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIW--------IEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRD-SGDNGNVIYRLQNDFDGT--------FEITESGEIY-TRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRL----FSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSE-NPGEKFRIEPQSGNI 2968 HSP 9 Score: 118.627 bits (296), Expect = 2.486e-26 Identity = 175/779 (22.46%), Postives = 317/779 (40.69%), Query Frame = 3
Query: 333 RIQDFDLSRRENLNFQMMKENNF---VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKI---QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFL-KPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFS-----FGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT----ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH---AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSP-DGRIFTTK------ESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEI-IRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLP 2579
R D D L F ++ E+ + G++ +DRE + +L ++ + I +++ + IS+ D+ND+ P + + + +PE G + A DLD +N++ YT+ + Y + KT + L + +++ A D G L+ LT+ I + P F + ++ E+ + + ++ A K+ ++ G+S+ ++ S G++G LDY+ + Y + I+ D + + T++ + V + NDNAPV+ L + N ++EE + IA + A+D D+ G + R+ D + T I LDRE + ++ D G P T + + +LDKND P F + ++ + E + SFV ++ +SD D+G N+ Y F I+ +G + DRE+ EY L+ D + T I + I+D ND AP F+ FY FS PE VG ++A D D + N ISY++ FS+ P G +F+ K R +M++ ++ A D+G V + I D ++N P++ + L + ++ G+ + + A D + ++Y ++ N +F + + G + L+K P+ P LVV+ +D G P ++ T V I E P
Sbjct: 2514 RATDKDEGLNAKLRFNLLGEHMHRFHIDSETGEISTATTLDRE-------ETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDG-ENAVVHYTISGRDQH--------YFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDG-------LDYEL-THLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIY-----NAEVLEEESPPQL-IAVVKASDRDSGDN---------GNVIYRLQNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASD-----------GAWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSL---------QQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLA---PLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWITLVK-PIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTP 3227 HSP 10 Score: 117.087 bits (292), Expect = 7.213e-26 Identity = 193/806 (23.95%), Postives = 338/806 (41.94%), Query Frame = 3
Query: 234 DFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMK---ENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVF-----LKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFA---------------ETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT-ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVS--VDVVVKIEDLND--NFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXX-XYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
D P K + SL V E++EIG + + + D DL N ++ + E + +G + V +DRE ++++ + +V + I I+I+D ND++P + S + PE + + +A D D NS+ Y+L+ + +FSI + + + + + + R L +LA D+G PPL + INI D ++N P F L PL + +++ Q + ++ A D +++ +S M S F + +G I T + PIQV +T++ ET +++ V EN + P S VNS ++V EN + I ++ ATD D + S SGG + D SV + I++ + LD + + + I QD GY P + ++ I + D ND P F YI E PV +FV + +A+D D N+ + Y D F ++++ G + + FD E+ Y L+ + + + + S + V + +N+ P F + + F + E S+ VG+V A D D R Y +++ K F + + + LDRET + ++ A + G I + V++ I+D ND F + ++S I+ VG VT +KA+D D ++ +Y II GN + FK++ ++G + + + LV+ D+G P T + V I
Sbjct: 2908 DNPPKFTRLFSLN--VTENAEIGSFVIRVTSS----DLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDRE----QQDEY----ILKVVASDGAWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPS----PMFSI--DPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVR-----GQRIVRVHANDKQDLGTNEMDYSL---MTFNLSSIFSVGRHDGWI-------------TLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFS----VNSYQ--VIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQ----DFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQ---------IKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGR--VYYLLVGSSNDKG------FRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDPPEFIKHYYTS------TISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHI 3639 HSP 11 Score: 113.62 bits (283), Expect = 8.800e-25 Identity = 196/765 (25.62%), Postives = 317/765 (41.44%), Query Frame = 3
Query: 339 QDFDLSRRENLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSG-SPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFI--DQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGY-PPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI---DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLF-YEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPD-GRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRFF 2597
+D D+ + + L F + + +G+L V +DRE LN+ QS ++ I I D ND+SPV+ + ++ E++ IG+ A D+D + I RY++ V Q FSI ++ ++RV N++ E++ + L + AED P + LTINI DINDN P FL + EN Y+ + A D D + F + D F IN +G I + + LD +Q+ + Y L + D+ I+ V+VQ+ NDN PV + + + V EN+ T + + ATD D + G + R D I LDRE + T+ QD P+ ++ + I V D ND P F + V + E + FV A D D G N+ + Y I D +F I+ TGV+ T + L T+ + D E+ LSS + VI++ + P F + F++ E P + V A S + + +I YA+ I V P+ G + ++ LD E ++ IEA D + R + + + D NDN P L + + EE+ +L+ V+KA D DSG N ++ Y +Q + F++ + SG +Y + + VV+ D G +T T V ++ + P +R F
Sbjct: 2209 RDEDMGQSDPLPFSL-------NPTDGQLRVVDALDREL-----RSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRI-RYSI--VLGDQNHDFSISEDTG---------VVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYF---LKEGDSDLFRINASSGDIALLKPLDREQQ-SEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHAT------VRENLPSGTHVLTPRATDKDEGLNAKLRFNLL-GEHMHRFHIDSET---GEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIV----ISAMDQGEQSLSSKAELTVILRP-PELFPTFAYMANSHFAMSEDVRPGKMITKVSAT-SPKKGLVGKIRYAIA-------GGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQ---LIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYR-LQNDFDGTFEITE-SGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLF 2917 HSP 12 Score: 107.457 bits (267), Expect = 6.112e-23 Identity = 158/609 (25.94%), Postives = 247/609 (40.56%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQ-----LKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVT--DSTKFAETILLVKVQNENDNAP-VISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTK----IINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGV-NSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSI 2291
QS+ + I + N +P ++ + + +PE+ +GS A D D+ P N + RY++ N Q + IV D + + L + +D G PL+ LTI +TD+NDN PVF I EN + ++ Q A D D N + ++F S DR F +N NG I DY +E Y L I+ DS+ + L V V N+ P + + H + V E T + ++ ATD D+ G K R+ T+ + I + + LDRET T+ ++ G T II+IQ D ND P F T I E PV + VT + A D DV N+Q Y I + + F ID TG + T S DRE+T Y L +D+ + S+T + + ++D+ND P F I E + +++A D D+ +Y ++ + K + SV + + + S DRE + IE DSG + + + + D NDN P + S + +S+
Sbjct: 3209 QSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGP-NGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNI----------------TVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSG--PDRHFFIMNQSNGTISSAVSFDY-EERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFD-------VSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGL-----IYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQ--DGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVI------GAIDTGLPPQTGSAT--VHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKH-------KSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDN-PSTTRSLHIAVSL 3766 HSP 13 Score: 92.8189 bits (229), Expect = 1.891e-18 Identity = 96/389 (24.68%), Postives = 171/389 (43.96%), Query Frame = 3
Query: 1458 TKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA--HFSIDENTGVLRTNSIFDREKTGEYKLEA-------TVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYE-----FSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSND-PEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLP 2579
T LDRE+ +Q I +D G PP+ +N+ +LD ND P F + V ++E + V + ASD D+G NS++ Y + F+++ TGV+ T + + K A TV+ R D T + V + D ND P+ F+ ++ E + V +V +DSD +N + S +V + + + + D I LDRE ++ ++ A D G + +++ + D+ND+ P + S S ++ G V + A D D+G+N+ ++Y+I+ GNE + F ++ +G L + PL + + + L + D GP+P T +++ E + P
Sbjct: 225 TGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFAR------DHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSD-SGLNGRTSVRIV-----SGNELGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSE---YSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTG-LIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAP 597 HSP 14 Score: 87.0409 bits (214), Expect = 9.555e-17 Identity = 122/495 (24.65%), Postives = 210/495 (42.42%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTY--LNQ----LLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFA-----ETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD--NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNS-----QLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSD-PTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSP 1967
+ I + D+ND+ PV+ + IPE+ +G+ + A D DS P N+I Y S PD+ + +NQ + V + + +I +++ DS + +L +++ +N+ P FL+P+ + E + + + + A D D ++ ++ + S N D+ F I+ G I+V + LD + + N +L + + E +++ +Q+ ND I H +S + E T + ++ A D D + S + +G LK S + V I LDRE + I D G PPQ + ++I++ D ND P F YI E P + + L ASD D+ N QL+ + S+D N+GV+R+ + FDRE T LEA + + DS P +K S ++ + + D ND + L S+ G P
Sbjct: 3320 LTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDS-PKNAIIHYAF--------------LPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDSS---MESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSN--DKG-FRIDTNTGLIYVARHLDRETQ-NRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDPPEFIK---HYYTST----ISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKID----VQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTP--ILEAII----EVEDSGKPKQK---SQHLLTITVLDQNDNPSTTRSLHIAVSLFNGDLP 3772 HSP 15 Score: 80.4925 bits (197), Expect = 9.462e-15 Identity = 169/740 (22.84%), Postives = 311/740 (42.03%), Query Frame = 3
Query: 429 VKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD----STKFAETILLVKVQNENDNAPVISILPHVNS---SNNVLLVEENIQDETAIASLSATDMDNXXXXXXX-XXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNAS-DCDVGV----------NSQLVYRI---DHAH-FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVF---KKLFYEFSIPEGSS--PRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDP-EIIRLVVKVSDSG-PSPLTNTTIVRIYFH 2558
V +DRE I K N L + + ++ + I + D+NDH PV+ +S+ + E + GS A D D+ N+ Y + ++ ++LK FS+ L L++ +DRE + +EL + A D G P T L + I D ND +P F + +++ E+ + M A D D N +TF+ S+ +F ++ G++ ++ LD ++++ Y + + D + + A + + V + NDN P ++ S ++ + +++ ++ E + ++A+D D+ + SGG L ++ ++ + P ++ + +D G I+ I + K + A E VE + N+ + +VG+ NS + Y I D A F ID +G + T DRE+ Y+L T+ + S V I+ + I D+ND APVF ++ S+PE ++ +Y+ V D+ +N +ISY++ P + F + P + + + E + + A D+G + + V I D+ND+ P + H+S ++ V L A D D G N ++YEII+GN +F + G L++ + PL + + L V D+G PS +++V + H
Sbjct: 448 VNGVLDREEIG-KYN----LTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGV-NAQVHYDI--LSGNELKWFSM--------DPLTGLIVTT-GPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDR-EKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGEGLFQLDARSGAIS---LRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQAGGY---EFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSGRITTARPLDREEQANYRL--TILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDA---GVNSRISYSLTNNPNQQ--------FRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTS---YETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVF-PDGYLFV-RAPLDREERDYYALTVSCRDAGQPS---RSSVVPVVIH 1142 HSP 16 Score: 77.411 bits (189), Expect = 9.692e-14 Identity = 133/550 (24.18%), Postives = 225/550 (40.91%), Query Frame = 3
Query: 1074 DRSK-FYINGKNGKIFVKQILDYDQEVNTYLLPI---------QVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTD-------LSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENT---------GVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAM-----------------VIKPYETKS--HISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAW--DSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVSKLP 2579
DR++ F I+ ++G+I + LD +++ N Y L I S + + I+ + + + NDNAPV ++ S + + EN I D D ++S LT+ + VT + L +P+ E + D G PP + +++ + D ND TP F + E V + L A+D D+G N ++ Y I I+ NT G L + DRE+ Y L TV R D + SS + + + D ND AP F + FSIPE + +VG + A D DI N ++S+ + ++P++ ++ +S+ + DG + R + + +EA D+G + V V V + D+NDN P++ + + I+ + G +T + D+D GLN + Y + +GNE F L+ +G L L ++ EI L+V D+ PL++ + I E P
Sbjct: 874 DRAQNFRIDTRSGRITTARPLDREEQAN-YRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFAL---DRESEPTISLPENAAVGQEIYLSRVRDRDAGVNS----------RISYSLTNNPNQQFRIGPVTG-VLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEI------IEGNTERMFGVFPDGYLFVRAPLDREERDYYAL--TVSCR------DAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDI-GRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSL--------RGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAP---YHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAP 1382 HSP 17 Score: 52.373 bits (124), Expect = 3.037e-6 Identity = 54/196 (27.55%), Postives = 89/196 (45.41%), Query Frame = 3
Query: 1725 FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRI----FTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINIT 2300
F++D TG ++TN + DRE ++ YD ++ S PT + +R+ + D+ND +P F + S E ++ + A D+D+ Y +V + K +L + +P G T +LDRE+ + +I A D G + V V I D+NDN P + H SD +S+N T
Sbjct: 103 FTLDPVTGEVKTNVVLDREGMRDH------YDLV-VLSSQPTYPIE-----VRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNK---FRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDH-SDYNVSLNET 282
BLAST of Protocadherin vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 174.096 bits (440), Expect = 2.460e-43 Identity = 183/686 (26.68%), Postives = 314/686 (45.77%), Query Frame = 3
Query: 528 NYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTF--------SFGNSMNIEDRSK-FYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD---NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFP-AAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-------DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAM-------VIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIE--DLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEII----QGNEHE-----LFKLNQKSGSLYLMKQPL 2462
+ ++ I +ED+ND++P + S + I++PE +++G+ Y A D DS S + T V S LF+I S L+L ++D E ++ L++ A D G P L+ + + +++ D+NDN PVF K +++ E+ I+ + Q+ A DLD +N ++T+ + NS++ D S+ F I +G I+++ LD + + Y L + TD+ A+T ++V+V + NDN P S +EEN++ + + ++A+D+D N++ S + ++ V ++S +PLDRE E + ++ +D G P + + I V D ND P V + E P + V ++ A D D G N+ + Y I H FSID +GV+RT + D E+ Y+L D N P E V ++RV + D+ND P F F + E ++ VGS+ + + + + + + P TK I + G + + LDRE I A D+ + S + VKIE D+NDN P+W + + ++ VG ++ A D+D+G N L Y +I Q NE + LF+++ +G+L L + PL
Sbjct: 913 GHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDS---GSSGQVTYSLVKESGKGLFAIDARS-------GHLIL--SQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETR-DRYQLTVLATDNGTPAAHAKTRVIVRVLDANDND------PKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEIST--------REPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGN----PPRETV----RMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPL-TKDLIEAAFDIDRHSGNLVVAR-LLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDP---IDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSL-QAPL 1557 HSP 2 Score: 169.859 bits (429), Expect = 4.592e-42 Identity = 183/694 (26.37%), Postives = 320/694 (46.11%), Query Frame = 3
Query: 417 GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVN-NSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLV--KVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLT--DLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-----DHAH-FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSV-SPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW---SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMK 2453
G++ K +DRE T+ + + + + ++++D ND++P + Q+ + I PE++ + L A+DLD P N+ RY + N N +L S + YL+ L++ +DRE LL+ A D G+PPL G + I I D+NDN P+F + ++ EN + + Q++A D D +N + ++ N + F I+ + G I++ + LD++ + L+ + + ET V +V + NDN P I+++ S + + E+ Q +A +S D D+ + + + G LT D S+ Y +++ PLDRE + ++ D G PP +K I +++ D ND P F + + E + V ++ A D D G+NS L Y + HA F ID TG++ T S D E +L +V D LSST + V I D+ND P+F + FY S+ E + V A D D +N ++Y + E H+++ F V S G I E LD E + F + A D G ++ + + +++ D+NDN P + + L S + + + +V V+ A D D G ++Y I+ GNE +F++++ +G +++++
Sbjct: 130 GEIRTKVKLDRE---TRASYSLVA--------IPLSGRNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNT-QRYNIVSGNVNDAFRLSS--HRERDGVLYLD---LQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAI-NRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVI--FLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSI---YLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQL--------TVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDC-GVNAMVNYTI----GEGFKHLTE--FEVRSASGEICIAGE-LDFERRSSYEFPVLATDRGGLS--TTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVV-ATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVR 781 HSP 3 Score: 141.739 bits (356), Expect = 2.026e-33 Identity = 136/504 (26.98%), Postives = 224/504 (44.44%), Query Frame = 3
Query: 861 GSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD--NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTIL-------LTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI--DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYE-FSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLV 2327
G PP+ G T + I + D+NDN+P F + IS+ E+ + L A D D + ++T+S + + F I+ ++G + + Q LDY+ + L + TD + +LV VQ+ NDN PV + V E+ I ++A+D+D N++ I +G ++ ++ V + I L PLDRET + +Q T+ D+G P + ++VLD ND P F + I+E + S V + ASD D+G N+ + Y + ++ F + TG + T DRE Y L V + R D V S+ +R+ + D+ND AP + S+ E P V V A D D N I+Y+ ++K ++ H FS+ P + T+ LD E ++ + A D G + V++ DLNDN P ++ SS L + + +G +V
Sbjct: 907 GEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSL---VKESGKGLFAIDARSGHLILSQHLDYESS-QRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVF------EKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRELRELYDL---VVEAR-----DQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRD-HGQNASITYS-IVKGRDSDGH---GLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSS---LVFRVREDAALGHVV 1384 HSP 4 Score: 125.176 bits (313), Expect = 2.597e-28 Identity = 178/724 (24.59%), Postives = 307/724 (42.40%), Query Frame = 3
Query: 528 NYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSP----VFLKPLTEISIKENNFIDQYLCQMFAKDLDISD---NDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQI-LDYDQE-VNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISI-LPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT--KPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA-----HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMY-------VGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTK-ESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSS-DLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRFFEKDLV 2612
+ + I+I+D+ND+ P++ QS+ +PE++ +G+ A D D+ +N + Y + + + ++F I + Y+N+ L D E E EL+++A+D G PL + ++I +TD+NDN P +FL I E+ +++ ++ D D N +T + G+ F + ++ I++ + L D+E V+ Y L + TD A + +++ + NDN P L H N V E T++ + A D D S + + + T L+T +D ET Q T+ +D G PP +T + + + D ND P F + V + E PV + K++ASD D GVN+ + Y I F + +G + D E+ Y+ DR LS+T +I++ + D+ND PVF Y+ S+ E SP+ + +V+A D D Q+SY +V ++ I ++ S G IF + + L T MH +I A D G + V + I D P + + + + +I R VG ++ A D S + Y I G+ F + SG++ + K PL ++ + L+ + G P+ T V I EV + + FE +V
Sbjct: 268 GFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDAD-ENGLVEYAINRRQSDKEQMFRI--DPRTGAIYINKAL-------DFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDG-------HFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHAN-------VMEVADPGTSVLQVLAHDRDEGLNSALTYSLA---ETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGG----------LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRE--SPKASSQASSTPIVAVVATDPDYGNFG-QVSYRIVAG---NEAGIFRIDRST---GEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVI----AASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAK-PLDHEAKSQVLLNIQATLGEPPVYGHTQVNI----EVEDVNDNAPEFEASMV 936 HSP 5 Score: 122.479 bits (306), Expect = 1.411e-27 Identity = 167/705 (23.69%), Postives = 288/705 (40.85%), Query Frame = 3
Query: 267 LQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMK--------ENNFVSL-----VNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFE-------IQISIEDINDHSPVWTQ------SKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVN-------NSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSP-PLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK--------------------------FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKI-INIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA---HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG 2189
+ QV E + +G +I N+ D D +L +++++ + +SL + G L ++A +D E +IV L SN E +++ I D NDH+P + + I + ++IG +A D DS DN Y + N NSQ + +V SLP T + R + I A+D G P P S +L + + ++N P FL+ + +I EN ++ Q+ AK L ++N L++ + F+++ + G I + D + + +Y+LP+ V D+ + F + + V + NDN+P P S L V EN + I ++ A+D+D S +GG + S+ + L +PLDRE + + I+ D G P I I V D+ND P F + T + E P+ + V +++A D D+GVN++LVY + + F+ID +G++ T DRE Y D +V S+T +++ + DIND P+F++ Y +P P + V A D+D+ A N +I Y++ ++ F ++P + +SL E+ + + A D G
Sbjct: 1490 IDLQVSEATPVGTII----HNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFE---------AVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSG-DNGQLTYEITGGNGEGRFRINSQTGIIELV-KSLPPATEDVEKGGRFNLIIG------------AKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVA---NDLFHVDWQRGIITTRGQFDRESQA-SYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSP--EFRP---GSCYGLSVPEN-SEPGVIHTVVASDLDEGPNADLIYSITGG----NLGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRY-------EVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGA-NAEIVYSL-----NAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKG 2140 HSP 6 Score: 118.242 bits (295), Expect = 3.370e-26 Identity = 149/626 (23.80%), Postives = 271/626 (43.29%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGS--RYYLPLAKDLD---SSPDNSISRYTLKYVNNSQLK-LFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSP--PLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF------GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS----TKFAETILLVKVQ--NENDNAPVISILPHVNSSNNV-LLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSR--VLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYP-PQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA----HFSIDENTGVLRTNSIFDREKTGEYKLEATVYD--RRNLVDSDPTEKVLSSTTI-------------IRVIIKDINDCAPVFK-KLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVDVVVKIEDLNDNFPQWSHSSDLG 2282
+++ + D+ND+ P +T S +V + E + +G P+ + D +S + S + Y N K L ++ D+ N ++ R+ +DRE + L + A D+ + P + + + I + D+NDN+P + + ++ + E + + A D D N L + N + S F ++ G + ++ LD+ + V YLL +Q D T+ +T + V+++ + ND+AP + P+ + L + + + +A + A D D+ +GG R + + ++ L D E F I +D G P P+ ++ +++ V ++ P F A+ I E VP SFV ++ A N+ L Y I F +D G++ T FDRE Y L V D R++ + S K SS +I I + + D+ND +P F+ Y S+PE S P + + +V+A D D E N + Y++ T ++ + S G + + LDRE + ++ I+A D G P + + ++ + +ED NDN P++ S G
Sbjct: 1351 LRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDI--DRHSGNLVVARL---LDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDF-EAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHF-VSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLD-EGPNADLIYSI------TGGNLGNKFSIDSSSGEL--SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTG 1959 HSP 7 Score: 108.612 bits (270), Expect = 2.446e-23 Identity = 119/508 (23.43%), Postives = 227/508 (44.69%), Query Frame = 3
Query: 525 SNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFG--NSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPV---------ISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVF-KKLFYEFSIPEGSSPRMYVGSVLAEDSDIE 2012
++Y E+ I +ED ND+SP ++Q + V + E + G+ A D D+ N+ RY + N+ + ++ + +R + +DRE + +L ++A D G P +TG+ + + I D+NDN P F P +++ E + + + A D+D LT+ G ++++IE+ S F ++ +GK+ +K+ LDY+ + Y L + +D+ A T+L V+V +ENDNAPV +ILP ++ + E++ + + +++ATD D+ + + + V + +P + ++F I +D G P ++ ++ +Q D F I E P+ S V +L D + ++ + + F + ++ ++ + DRE+ YKL + + II ++ D ND P+F + YE I E + R + + A D+D E
Sbjct: 2303 ASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAG-SNARLRYHIVDGNHDNAFVIEPAFSGI----------VRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTF-PPNNLVTVSEATELGAVITSISANDVDTY--PALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQ-QEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISE------ISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYF-VRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSL--AIIAGNEESAFELLQSKAIVLVKPL-DRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITIL--DANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQE 2783 HSP 8 Score: 99.7525 bits (247), Expect = 1.187e-20 Identity = 151/595 (25.38%), Postives = 251/595 (42.18%), Query Frame = 3
Query: 807 IDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK--FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT-ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESF-----VTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTG---VLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIV 2543
+DRE + L ++A D G+PPL S + + ITD+NDN P F + L ++ E + Q+ A D D N LT+S + + F I+ + G I + +D + E L + + +LV + + NDN P+ + S + V EN I +SA+D D + + G K LT+ V + I + LD E ++ + D G TT +I +Q+ D ND P F V + E S + + A+D D G Q+ YRI + F ID +TG V+R + + R + + L + D NL + + ++ + I D P+F+K Y + + E VGSV+A D+ A + Y++ S YFS+ + + LD E +I+A P + V +++ED+NDN P++ S + I++ +G + A D DSG + + Y +++ + LF ++ +SG L L + + L+V +D G PS TN TI+
Sbjct: 462 LDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQ-WFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIF------DQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKH---LTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQP-MHMLNISATDGGNLRSN--------ADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDV-AHRSPVRYSIY-------SGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYG-HTQVNIEVEDVNDNAPEFEASM---VRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTIL 1023 HSP 9 Score: 96.6709 bits (239), Expect = 1.132e-19 Identity = 187/834 (22.42%), Postives = 336/834 (40.29%), Query Frame = 3
Query: 270 QFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNF--VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLK-----IQSNYFEIQISIEDINDHSP-VWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQM--FAKDLDISDND--------KLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT-YLLPIQVTDST-----KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD-----------------------NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF------PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLR-----TNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDS--------------------GPITHRVSVDVV---VKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEI-IRLVVKVSDSG 2513
+F+++E+ G ++G + + D DL + + ++ N+ V V G++ + +DRE L+ +V + ++S ++I + D+ND++P + + V+++ E G+ A D D + SI+ +K ++ LFSI D T ++R +D E+ L + A D G+PP L + + D+NDN P F ++E+ + + + + D+ N ++T++ + F I+ +G + V ++LD +EV + + L I+ D+T + + + ++V + NDNAP P L V E T I + +ATD D + ++ S +G L L L D V +Y +L+ + LD+ +N T + Q T+ + +++LD ND PHF +++I + + V + A D D G N QL Y I F I+ TG++ + D EK G + L + ++ +P + L+ + +I++ ++ P F + Y +I E +V V A+ S A N +SY E + ++ F V I TT+ DRE+ + + D+ G ++ DV + + D+NDN P++ S GLS+ E V + + A D D G N+ L Y I GN F ++ SG L +PL + L ++ SD G
Sbjct: 1159 EFRIEENLRRGSVVGVVTAS----DLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRE----------LRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSI------DPT---SGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLD--REVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPID------LQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPL-DFEAVQEY-LLIVQALDQSSN----VTERLQ--------TSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNL---IIGAKDHGQPEPKKSSLN----LHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAK-SLHGAENANLSY-------EIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV---IHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGE--LSARPLDREQHSRYTLQIQASDRG 1927 HSP 10 Score: 92.8189 bits (229), Expect = 1.899e-18 Identity = 148/656 (22.56%), Postives = 271/656 (41.31%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIV-INIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDAN-IDRXXXXXXXXXXXXXDSGSP-PLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQ----NENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTI-------LLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTP--HFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTN---------------SIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTI---------IRVII--------------------KDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW--------SHSSDLGLSI 2291
I I++ D+ND+SP + +++PE+S+ G + + +A DLD P+ + ++SI +L +K ++ + A +DRE+ + L + A D G P G ++TI + D NDN+P F S++E+ + + Q+ A D D+ N +L +S N E + +F I+G++G I LD + + +Y + TD ++ V VQ + NDN P+ P++ V IQ + + A D D ++ + S + +V K+ I ++ L E+ + + +D G PPQ + +I + + + TP F V + E P + + ++ A D G ++ + + S+D +G +R N S R + Y+ E + +S +++ L+S++ IRV++ +D ND +P F + + ++ EG++ +V V A DSD + N ++ Y +V ++ I + I T LDRE D++ I A D G + + V+I D+NDN P + S +++LG I
Sbjct: 1833 IYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTV-VASDLDEGPNADL--------------IYSITGGNLGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLAN----ETQWQFAIDGQSGLITTVGKLDRELQA-SYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQ------VPALIQPGQTLLKVQALDAD--------LGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGS-NARLRYHIVDGNHDNAFVIEPAFSG------IVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVI 2446 HSP 11 Score: 84.7297 bits (208), Expect = 4.432e-16 Identity = 88/284 (30.99%), Postives = 127/284 (44.72%), Query Frame = 3
Query: 1725 FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVL-AEDSDIEAINRQ---ISYAMVIKPYETKSHISK---LYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI--IQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
+ID TG +RT DRE Y L A RN+ +VL V +KD ND AP F + PE ++PR ++L A D D+E N Q I V + SH + LY + G LDRET +S IEA D G R + V + I+D+NDN P ++ S + TVG V + A D+D+ N + Y I Q ++ ++F+++ ++G++Y+ K E+ LVV D G PL T V I
Sbjct: 123 LAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNI-------RVL-------VTVKDENDNAPTFPQTSMHIEFPE-NTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISG-------FLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFA---TVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSI 381 HSP 12 Score: 79.337 bits (194), Expect = 2.025e-14 Identity = 142/604 (23.51%), Postives = 255/604 (42.22%), Query Frame = 3
Query: 864 SPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEV-NTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT--ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVY---------IDEGVPVESFVTKLNASDCDV-GVNSQLVYRIDHAH--FSIDENTGVLRTNSIFDR-----EKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHI--SKLYFSVSPDGRIFTTKESLDRETYDMHSFS-IEAWDSGP-----ITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXX--XXXXYEIIQGNEHELFKLNQKSGSLYLMKQ-PLSNDPEIIRLVVKVSDS-GPSPLTNTTIVRIYFHSE 2564
+P L L I + D NDNSP F + ++ E N ++ Q+ A D D N +L + GN N F I I I+ D+E+ + Y L I TD + V++ + NDN P NN++ V E + I S+SA D+D + + + + + + + +Y+ ++L + LD E + ++ + D + + ++ ++V D+ND P F A Y I E + V+ + +NA+D D G NS+++Y I+ A FS+ + GV+ N R +G+Y + ++ D + L S+T++RV D F + Y I E + +GSV+ + +A+++ S A++ E+ + SK V P LDRE D++ + + GP + + V++ I D NDNFP + S+ I+ + + L+A+D+D S + Y+I GN+ +F ++ +G L++ + + + L+++ DS PL + R+ H E
Sbjct: 2299 APFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDN-----AFVIEPAFSGIVRTNIV-LDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFP-------PNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENM--SIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEART---VLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVN--MSRLQPAVSSSGDYFVR--------IIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAP----LGSVVLQLGQ-DALDQ--SLAIIAGNEESAFELLQSKAIVLVKP----------LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKY--EAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDE 2855 HSP 13 Score: 65.855 bits (159), Expect = 2.603e-10 Identity = 102/408 (25.00%), Postives = 164/408 (40.20%), Query Frame = 3
Query: 855 DSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT-YLL---------PIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD--NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETN-EFFQATIK-CQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA--------HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSS-PRMY-VGSVLAEDSD 2006
D+G P L ST L + D FL+ I E + + Q+ LD S L GN + S F + + VK + D+E N Y L P ++ + +++ + + NDN P+ S+ + E +IA L A D D N+ + G DL VT + + LD ++ + ++ I+ C P + + +++ D+ND P FP ++ E PV S V + +ASD D G QL Y I A F +D +G++ + +FD E+ Y +E L+ SD K ++ +RV I+ ++ P F + Y F +P + P+ Y VG V A DSD
Sbjct: 2622 DAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS----LAIIAGN-----EESAFELLQSKAIVLVKPL---DRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFD-----RSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDL--VTG-VLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDME--------LLASDMGGK--KASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSD 2999
BLAST of Protocadherin vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0343249) HSP 1 Score: 174.096 bits (440), Expect = 2.460e-43 Identity = 183/686 (26.68%), Postives = 314/686 (45.77%), Query Frame = 3
Query: 528 NYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTF--------SFGNSMNIEDRSK-FYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD---NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFP-AAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-------DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAM-------VIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIE--DLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEII----QGNEHE-----LFKLNQKSGSLYLMKQPL 2462
+ ++ I +ED+ND++P + S + I++PE +++G+ Y A D DS S + T V S LF+I S L+L ++D E ++ L++ A D G P L+ + + +++ D+NDN PVF K +++ E+ I+ + Q+ A DLD +N ++T+ + NS++ D S+ F I +G I+++ LD + + Y L + TD+ A+T ++V+V + NDN P S +EEN++ + + ++A+D+D N++ S + ++ V ++S +PLDRE E + ++ +D G P + + I V D ND P V + E P + V ++ A D D G N+ + Y I H FSID +GV+RT + D E+ Y+L D N P E V ++RV + D+ND P F F + E ++ VGS+ + + + + + + P TK I + G + + LDRE I A D+ + S + VKIE D+NDN P+W + + ++ VG ++ A D+D+G N L Y +I Q NE + LF+++ +G+L L + PL
Sbjct: 913 GHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDS---GSSGQVTYSLVKESGKGLFAIDARS-------GHLIL--SQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETR-DRYQLTVLATDNGTPAAHAKTRVIVRVLDANDND------PKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEIST--------REPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGN----PPRETV----RMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPL-TKDLIEAAFDIDRHSGNLVVAR-LLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDP---IDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSL-QAPL 1557 HSP 2 Score: 169.859 bits (429), Expect = 4.592e-42 Identity = 183/694 (26.37%), Postives = 320/694 (46.11%), Query Frame = 3
Query: 417 GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVN-NSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLV--KVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLT--DLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-----DHAH-FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSV-SPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW---SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMK 2453
G++ K +DRE T+ + + + + ++++D ND++P + Q+ + I PE++ + L A+DLD P N+ RY + N N +L S + YL+ L++ +DRE LL+ A D G+PPL G + I I D+NDN P+F + ++ EN + + Q++A D D +N + ++ N + F I+ + G I++ + LD++ + L+ + + ET V +V + NDN P I+++ S + + E+ Q +A +S D D+ + + + G LT D S+ Y +++ PLDRE + ++ D G PP +K I +++ D ND P F + + E + V ++ A D D G+NS L Y + HA F ID TG++ T S D E +L +V D LSST + V I D+ND P+F + FY S+ E + V A D D +N ++Y + E H+++ F V S G I E LD E + F + A D G ++ + + +++ D+NDN P + + L S + + + +V V+ A D D G ++Y I+ GNE +F++++ +G +++++
Sbjct: 130 GEIRTKVKLDRE---TRASYSLVA--------IPLSGRNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNT-QRYNIVSGNVNDAFRLSS--HRERDGVLYLD---LQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAI-NRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVI--FLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSI---YLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQL--------TVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDC-GVNAMVNYTI----GEGFKHLTE--FEVRSASGEICIAGE-LDFERRSSYEFPVLATDRGGLS--TTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVV-ATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVR 781 HSP 3 Score: 141.739 bits (356), Expect = 2.026e-33 Identity = 136/504 (26.98%), Postives = 224/504 (44.44%), Query Frame = 3
Query: 861 GSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD--NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTIL-------LTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI--DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYE-FSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLV 2327
G PP+ G T + I + D+NDN+P F + IS+ E+ + L A D D + ++T+S + + F I+ ++G + + Q LDY+ + L + TD + +LV VQ+ NDN PV + V E+ I ++A+D+D N++ I +G ++ ++ V + I L PLDRET + +Q T+ D+G P + ++VLD ND P F + I+E + S V + ASD D+G N+ + Y + ++ F + TG + T DRE Y L V + R D V S+ +R+ + D+ND AP + S+ E P V V A D D N I+Y+ ++K ++ H FS+ P + T+ LD E ++ + A D G + V++ DLNDN P ++ SS L + + +G +V
Sbjct: 907 GEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSL---VKESGKGLFAIDARSGHLILSQHLDYESS-QRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVF------EKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRELRELYDL---VVEAR-----DQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRD-HGQNASITYS-IVKGRDSDGH---GLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSS---LVFRVREDAALGHVV 1384 HSP 4 Score: 125.176 bits (313), Expect = 2.597e-28 Identity = 178/724 (24.59%), Postives = 307/724 (42.40%), Query Frame = 3
Query: 528 NYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSP----VFLKPLTEISIKENNFIDQYLCQMFAKDLDISD---NDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQI-LDYDQE-VNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISI-LPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT--KPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA-----HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMY-------VGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTK-ESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSS-DLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRFFEKDLV 2612
+ + I+I+D+ND+ P++ QS+ +PE++ +G+ A D D+ +N + Y + + + ++F I + Y+N+ L D E E EL+++A+D G PL + ++I +TD+NDN P +FL I E+ +++ ++ D D N +T + G+ F + ++ I++ + L D+E V+ Y L + TD A + +++ + NDN P L H N V E T++ + A D D S + + + T L+T +D ET Q T+ +D G PP +T + + + D ND P F + V + E PV + K++ASD D GVN+ + Y I F + +G + D E+ Y+ DR LS+T +I++ + D+ND PVF Y+ S+ E SP+ + +V+A D D Q+SY +V ++ I ++ S G IF + + L T MH +I A D G + V + I D P + + + + +I R VG ++ A D S + Y I G+ F + SG++ + K PL ++ + L+ + G P+ T V I EV + + FE +V
Sbjct: 268 GFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDAD-ENGLVEYAINRRQSDKEQMFRI--DPRTGAIYINKAL-------DFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDG-------HFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHAN-------VMEVADPGTSVLQVLAHDRDEGLNSALTYSLA---ETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGG----------LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRE--SPKASSQASSTPIVAVVATDPDYGNFG-QVSYRIVAG---NEAGIFRIDRST---GEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVI----AASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAK-PLDHEAKSQVLLNIQATLGEPPVYGHTQVNI----EVEDVNDNAPEFEASMV 936 HSP 5 Score: 122.479 bits (306), Expect = 1.411e-27 Identity = 167/705 (23.69%), Postives = 288/705 (40.85%), Query Frame = 3
Query: 267 LQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMK--------ENNFVSL-----VNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFE-------IQISIEDINDHSPVWTQ------SKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVN-------NSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSP-PLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK--------------------------FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKI-INIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA---HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG 2189
+ QV E + +G +I N+ D D +L +++++ + +SL + G L ++A +D E +IV L SN E +++ I D NDH+P + + I + ++IG +A D DS DN Y + N NSQ + +V SLP T + R + I A+D G P P S +L + + ++N P FL+ + +I EN ++ Q+ AK L ++N L++ + F+++ + G I + D + + +Y+LP+ V D+ + F + + V + NDN+P P S L V EN + I ++ A+D+D S +GG + S+ + L +PLDRE + + I+ D G P I I V D+ND P F + T + E P+ + V +++A D D+GVN++LVY + + F+ID +G++ T DRE Y D +V S+T +++ + DIND P+F++ Y +P P + V A D+D+ A N +I Y++ ++ F ++P + +SL E+ + + A D G
Sbjct: 1490 IDLQVSEATPVGTII----HNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFE---------AVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSG-DNGQLTYEITGGNGEGRFRINSQTGIIELV-KSLPPATEDVEKGGRFNLIIG------------AKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVA---NDLFHVDWQRGIITTRGQFDRESQA-SYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSP--EFRP---GSCYGLSVPEN-SEPGVIHTVVASDLDEGPNADLIYSITGG----NLGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRY-------EVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGA-NAEIVYSL-----NAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKG 2140 HSP 6 Score: 118.242 bits (295), Expect = 3.370e-26 Identity = 149/626 (23.80%), Postives = 271/626 (43.29%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGS--RYYLPLAKDLD---SSPDNSISRYTLKYVNNSQLK-LFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSP--PLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF------GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS----TKFAETILLVKVQ--NENDNAPVISILPHVNSSNNV-LLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSR--VLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYP-PQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA----HFSIDENTGVLRTNSIFDREKTGEYKLEATVYD--RRNLVDSDPTEKVLSSTTI-------------IRVIIKDINDCAPVFK-KLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVDVVVKIEDLNDNFPQWSHSSDLG 2282
+++ + D+ND+ P +T S +V + E + +G P+ + D +S + S + Y N K L ++ D+ N ++ R+ +DRE + L + A D+ + P + + + I + D+NDN+P + + ++ + E + + A D D N L + N + S F ++ G + ++ LD+ + V YLL +Q D T+ +T + V+++ + ND+AP + P+ + L + + + +A + A D D+ +GG R + + ++ L D E F I +D G P P+ ++ +++ V ++ P F A+ I E VP SFV ++ A N+ L Y I F +D G++ T FDRE Y L V D R++ + S K SS +I I + + D+ND +P F+ Y S+PE S P + + +V+A D D E N + Y++ T ++ + S G + + LDRE + ++ I+A D G P + + ++ + +ED NDN P++ S G
Sbjct: 1351 LRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDI--DRHSGNLVVARL---LDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDF-EAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHF-VSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLD-EGPNADLIYSI------TGGNLGNKFSIDSSSGEL--SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTG 1959 HSP 7 Score: 108.612 bits (270), Expect = 2.446e-23 Identity = 119/508 (23.43%), Postives = 227/508 (44.69%), Query Frame = 3
Query: 525 SNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFG--NSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPV---------ISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVF-KKLFYEFSIPEGSSPRMYVGSVLAEDSDIE 2012
++Y E+ I +ED ND+SP ++Q + V + E + G+ A D D+ N+ RY + N+ + ++ + +R + +DRE + +L ++A D G P +TG+ + + I D+NDN P F P +++ E + + + A D+D LT+ G ++++IE+ S F ++ +GK+ +K+ LDY+ + Y L + +D+ A T+L V+V +ENDNAPV +ILP ++ + E++ + + +++ATD D+ + + + V + +P + ++F I +D G P ++ ++ +Q D F I E P+ S V +L D + ++ + + F + ++ ++ + DRE+ YKL + + II ++ D ND P+F + YE I E + R + + A D+D E
Sbjct: 2303 ASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAG-SNARLRYHIVDGNHDNAFVIEPAFSGI----------VRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTF-PPNNLVTVSEATELGAVITSISANDVDTY--PALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQ-QEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISE------ISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYF-VRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSL--AIIAGNEESAFELLQSKAIVLVKPL-DRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITIL--DANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQE 2783 HSP 8 Score: 99.7525 bits (247), Expect = 1.187e-20 Identity = 151/595 (25.38%), Postives = 251/595 (42.18%), Query Frame = 3
Query: 807 IDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK--FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT-ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESF-----VTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTG---VLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIV 2543
+DRE + L ++A D G+PPL S + + ITD+NDN P F + L ++ E + Q+ A D D N LT+S + + F I+ + G I + +D + E L + + +LV + + NDN P+ + S + V EN I +SA+D D + + G K LT+ V + I + LD E ++ + D G TT +I +Q+ D ND P F V + E S + + A+D D G Q+ YRI + F ID +TG V+R + + R + + L + D NL + + ++ + I D P+F+K Y + + E VGSV+A D+ A + Y++ S YFS+ + + LD E +I+A P + V +++ED+NDN P++ S + I++ +G + A D DSG + + Y +++ + LF ++ +SG L L + + L+V +D G PS TN TI+
Sbjct: 462 LDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQ-WFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIF------DQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKH---LTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQP-MHMLNISATDGGNLRSN--------ADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDV-AHRSPVRYSIY-------SGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYG-HTQVNIEVEDVNDNAPEFEASM---VRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTIL 1023 HSP 9 Score: 96.6709 bits (239), Expect = 1.132e-19 Identity = 187/834 (22.42%), Postives = 336/834 (40.29%), Query Frame = 3
Query: 270 QFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNF--VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLK-----IQSNYFEIQISIEDINDHSP-VWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQM--FAKDLDISDND--------KLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT-YLLPIQVTDST-----KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD-----------------------NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF------PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLR-----TNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDS--------------------GPITHRVSVDVV---VKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEI-IRLVVKVSDSG 2513
+F+++E+ G ++G + + D DL + + ++ N+ V V G++ + +DRE L+ +V + ++S ++I + D+ND++P + + V+++ E G+ A D D + SI+ +K ++ LFSI D T ++R +D E+ L + A D G+PP L + + D+NDN P F ++E+ + + + + D+ N ++T++ + F I+ +G + V ++LD +EV + + L I+ D+T + + + ++V + NDNAP P L V E T I + +ATD D + ++ S +G L L L D V +Y +L+ + LD+ +N T + Q T+ + +++LD ND PHF +++I + + V + A D D G N QL Y I F I+ TG++ + D EK G + L + ++ +P + L+ + +I++ ++ P F + Y +I E +V V A+ S A N +SY E + ++ F V I TT+ DRE+ + + D+ G ++ DV + + D+NDN P++ S GLS+ E V + + A D D G N+ L Y I GN F ++ SG L +PL + L ++ SD G
Sbjct: 1159 EFRIEENLRRGSVVGVVTAS----DLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRE----------LRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSI------DPT---SGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLD--REVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPID------LQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPL-DFEAVQEY-LLIVQALDQSSN----VTERLQ--------TSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNL---IIGAKDHGQPEPKKSSLN----LHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAK-SLHGAENANLSY-------EIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV---IHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGE--LSARPLDREQHSRYTLQIQASDRG 1927 HSP 10 Score: 92.8189 bits (229), Expect = 1.899e-18 Identity = 148/656 (22.56%), Postives = 271/656 (41.31%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIV-INIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDAN-IDRXXXXXXXXXXXXXDSGSP-PLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQ----NENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTI-------LLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTP--HFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTN---------------SIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTI---------IRVII--------------------KDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW--------SHSSDLGLSI 2291
I I++ D+ND+SP + +++PE+S+ G + + +A DLD P+ + ++SI +L +K ++ + A +DRE+ + L + A D G P G ++TI + D NDN+P F S++E+ + + Q+ A D D+ N +L +S N E + +F I+G++G I LD + + +Y + TD ++ V VQ + NDN P+ P++ V IQ + + A D D ++ + S + +V K+ I ++ L E+ + + +D G PPQ + +I + + + TP F V + E P + + ++ A D G ++ + + S+D +G +R N S R + Y+ E + +S +++ L+S++ IRV++ +D ND +P F + + ++ EG++ +V V A DSD + N ++ Y +V ++ I + I T LDRE D++ I A D G + + V+I D+NDN P + S +++LG I
Sbjct: 1833 IYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTV-VASDLDEGPNADL--------------IYSITGGNLGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLAN----ETQWQFAIDGQSGLITTVGKLDRELQA-SYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQ------VPALIQPGQTLLKVQALDAD--------LGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGS-NARLRYHIVDGNHDNAFVIEPAFSG------IVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVI 2446 HSP 11 Score: 84.7297 bits (208), Expect = 4.432e-16 Identity = 88/284 (30.99%), Postives = 127/284 (44.72%), Query Frame = 3
Query: 1725 FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVL-AEDSDIEAINRQ---ISYAMVIKPYETKSHISK---LYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI--IQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
+ID TG +RT DRE Y L A RN+ +VL V +KD ND AP F + PE ++PR ++L A D D+E N Q I V + SH + LY + G LDRET +S IEA D G R + V + I+D+NDN P ++ S + TVG V + A D+D+ N + Y I Q ++ ++F+++ ++G++Y+ K E+ LVV D G PL T V I
Sbjct: 123 LAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNI-------RVL-------VTVKDENDNAPTFPQTSMHIEFPE-NTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISG-------FLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFA---TVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSI 381 HSP 12 Score: 79.337 bits (194), Expect = 2.025e-14 Identity = 142/604 (23.51%), Postives = 255/604 (42.22%), Query Frame = 3
Query: 864 SPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEV-NTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT--ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVY---------IDEGVPVESFVTKLNASDCDV-GVNSQLVYRIDHAH--FSIDENTGVLRTNSIFDR-----EKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHI--SKLYFSVSPDGRIFTTKESLDRETYDMHSFS-IEAWDSGP-----ITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXX--XXXXYEIIQGNEHELFKLNQKSGSLYLMKQ-PLSNDPEIIRLVVKVSDS-GPSPLTNTTIVRIYFHSE 2564
+P L L I + D NDNSP F + ++ E N ++ Q+ A D D N +L + GN N F I I I+ D+E+ + Y L I TD + V++ + NDN P NN++ V E + I S+SA D+D + + + + + + + +Y+ ++L + LD E + ++ + D + + ++ ++V D+ND P F A Y I E + V+ + +NA+D D G NS+++Y I+ A FS+ + GV+ N R +G+Y + ++ D + L S+T++RV D F + Y I E + +GSV+ + +A+++ S A++ E+ + SK V P LDRE D++ + + GP + + V++ I D NDNFP + S+ I+ + + L+A+D+D S + Y+I GN+ +F ++ +G L++ + + + L+++ DS PL + R+ H E
Sbjct: 2299 APFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDN-----AFVIEPAFSGIVRTNIV-LDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFP-------PNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENM--SIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEART---VLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVN--MSRLQPAVSSSGDYFVR--------IIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAP----LGSVVLQLGQ-DALDQ--SLAIIAGNEESAFELLQSKAIVLVKP----------LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKY--EAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDE 2855 HSP 13 Score: 65.855 bits (159), Expect = 2.603e-10 Identity = 102/408 (25.00%), Postives = 164/408 (40.20%), Query Frame = 3
Query: 855 DSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT-YLL---------PIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD--NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETN-EFFQATIK-CQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA--------HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSS-PRMY-VGSVLAEDSD 2006
D+G P L ST L + D FL+ I E + + Q+ LD S L GN + S F + + VK + D+E N Y L P ++ + +++ + + NDN P+ S+ + E +IA L A D D N+ + G DL VT + + LD ++ + ++ I+ C P + + +++ D+ND P FP ++ E PV S V + +ASD D G QL Y I A F +D +G++ + +FD E+ Y +E L+ SD K ++ +RV I+ ++ P F + Y F +P + P+ Y VG V A DSD
Sbjct: 2622 DAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS----LAIIAGN-----EESAFELLQSKAIVLVKPL---DRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFD-----RSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDL--VTG-VLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDME--------LLASDMGGK--KASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSD 2999
BLAST of Protocadherin vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0339463) HSP 1 Score: 157.918 bits (398), Expect = 1.908e-38 Identity = 182/679 (26.80%), Postives = 305/679 (44.92%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGK--IFVKQILDYDQEVNTYLLPIQVTDSTKFAETILL-VKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD----NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVY-----RIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREE----TVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDS 2510
+SN ++ +++ D ND++P + S+ ++ E+ +G A D D + I+ Y++ +++ F + + P ++ + +DRE+ + ++A+D G PP + S+ + I + D+NDN P F E ++ E+ + + A D D + GN+ R +F I +NG+ I + Q LDY QE +LL + TDS ++T + + + + N+ AP+ P+ S V E+ T + +SATD D T S GL + ++ T I+ PLDRET + T+ +D G P T + I V D ND P F + + I E V + V ++ ASD DVG+N ++ Y I+ F ID +G +RTN DRE + L A D+ S P LSST +++ ++D+ND P F +PE S VG + A D D E +N + Y+++ + + S + S ++ T E LD E+ + S P+ + ++++V D+NDN P D + N R+ +GR+ D+ ++ L+Y I+ GN L +LN SG L L Q +N P+ + V VSD
Sbjct: 669 RSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEIT-YSISERDDN----FPLAVD--PRTGWVQTI-----KPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNT-----RGRFAITSQNGRGLITIAQSLDYKQE-KRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSAS------VFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFS-INPQTG-AIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDK----GSPP----LSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPD-EGVNAVVHYSIIGG--DDSNAFSLVTRPGSERAQLLTMTE-LDYESTRKRFELVVRAASPPLRNDAHIEILVT--DVNDNAPVLR---DFQVIFNNFRDHFPSGEIGRIPAF------DADVSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSDG 1298 HSP 2 Score: 149.443 bits (376), Expect = 9.845e-36 Identity = 174/698 (24.93%), Postives = 306/698 (43.84%), Query Frame = 3
Query: 558 DINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVD---------ANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF------GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD------STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQ--DETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGR-IFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXY----EIIQG-NEHELFKLNQKSGSLYLMKQPLSND-PEIIRLVVKVSDSGPSPLTNTTIVRI 2549
++ + SP + Q+ V ++ E G+ A+D + SP +VY+ + +Q L +VD A++DRE ++ ++A D PP +G+T L +N+ D ND+SP F E SI+E + + + A D DI N ++ + ++ F I+ ++G I + LD + ++Y L + D + A + VKV ++NDN P S + V + E+ ++ +A + ATD D + + GG S+ D + L KPLD E+ ++ I+ QD G P + T + + V+D ND P F + + E VPV + ++ A D D G N+++ Y I D+ ++D TG ++T DRE+ G + + +V D S+++ + + ++D+ND P F +YE ++ E P V +V A D D ++ ++ Y + T + + S +GR + T +SLD + ++ A DSG + +V + I D N+ P + ++ S ++ + VG V V+ A DSD G+N+ + Y E I G + F +N ++G++ + PL + L V D G L++TT V I
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP---------------------VVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETS-DSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFS-----ERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSID---SMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQ--------VVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDS---RLHYEI------TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVH--INITDANNFAPIFENAP---YSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAI-VTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEI 995 HSP 3 Score: 129.028 bits (323), Expect = 1.733e-29 Identity = 186/714 (26.05%), Postives = 311/714 (43.56%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNS-------QLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXD---SGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFI---DQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVI-------SILPHVNSSNNVLLVEENIQDETAIASL--SATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT-KPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKV-LSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLY----FSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGN-EHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
+S +Q+++ D NDHSP + + +I E + +GS A D D + I Y ++ V + ++ +F I S ++ +++DRE + LL+ A D + S T + + + + D NDN P F + + + E+ + D + + A D D +N + ++ GN+ +S+F I+ +G + + + LDY + V +Y L I+ D ++ T LLV V + NDNAP S+L +V N++ V+ DE A A + S ++ D++ L+V + + T KPLDRE F + +D G PP+ + + I V D ND P F + E P + VT + A+D D +S+L Y I F+I G + ++ +YK E +R L+ T+ S T + + I D N+ AP+F+ Y S+ E + V V A DSD+ +N QI+Y++ + I+ L FS++P T LDRET + ++ A D G + + DV + + D+NDN P + S L +I + VG V + A D D GLN + Y + + E F ++ SG++ K + L D G PL++T V+I
Sbjct: 444 RSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEI-EYGIEAVTDGAGLAQDQEMPIFRIDSRSG---------VISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNT-----QSQFSIDSMSGDVSLVKPLDY-ESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFP-------------------LAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNG----RGLITIAQSLDYKQE-----KRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDV-GVNAQITYSL------NEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAF--KSPL-YQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQI 1101 HSP 4 Score: 67.0106 bits (162), Expect = 1.284e-10 Identity = 62/239 (25.94%), Postives = 113/239 (47.28%), Query Frame = 3
Query: 525 SNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQY----LCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYL-LPIQVTDSTKFAETILLVKVQ 1226
S+ E+QI +ED+ND P + KI + +PE+S +GS A D D N++ Y++ + FS+V ++ QLL + + + + ++ + SPPL H+ I +TD+NDN+PV L + + NNF D + + ++ A D D+SD GN+ N+ +N +G + + L+ + V + + + V+D A+ I+ + V+
Sbjct: 1094 SSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGV-NAVVHYSI--IGGDDSNAFSLVTRPGSERA---QLLTMTELDYESTRKRFELVVR----AASPPLRNDAHIEILVTDVNDNAPV----LRDFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRILSGNNANL-----LRLNSSSGGLVLSPQLNTN--VPKFATMEVSVSDGINEAKAIMQLSVR 1311 HSP 5 Score: 58.5362 bits (140), Expect = 4.529e-8 Identity = 61/221 (27.60%), Postives = 98/221 (44.34%), Query Frame = 3
Query: 1818 DRRNLVDSDPTEKVL------SSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI---------IQGNEHELFKLNQKSG 2435
DRR++VDSD K++ + T I R + +++ + +P F++ Y S+ E V +V A D + + + Y+MV S+ F V + TT SLDRE D+H F + A D + + V + D ND+ P + +I TVG V L+A D D G N+ + Y I Q E +F+++ +SG
Sbjct: 319 DRRDIVDSDHRLKIVYHHQEFNDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE----DSPVVYSMV----SLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQ---FEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSG 528
BLAST of Protocadherin vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0330601) HSP 1 Score: 157.918 bits (398), Expect = 2.174e-38 Identity = 182/679 (26.80%), Postives = 305/679 (44.92%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGK--IFVKQILDYDQEVNTYLLPIQVTDSTKFAETILL-VKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD----NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVY-----RIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREE----TVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDS 2510
+SN ++ +++ D ND++P + S+ ++ E+ +G A D D + I+ Y++ +++ F + + P ++ + +DRE+ + ++A+D G PP + S+ + I + D+NDN P F E ++ E+ + + A D D + GN+ R +F I +NG+ I + Q LDY QE +LL + TDS ++T + + + + N+ AP+ P+ S V E+ T + +SATD D T S GL + ++ T I+ PLDRET + T+ +D G P T + I V D ND P F + + I E V + V ++ ASD DVG+N ++ Y I+ F ID +G +RTN DRE + L A D+ S P LSST +++ ++D+ND P F +PE S VG + A D D E +N + Y+++ + + S + S ++ T E LD E+ + S P+ + ++++V D+NDN P D + N R+ +GR+ D+ ++ L+Y I+ GN L +LN SG L L Q +N P+ + V VSD
Sbjct: 669 RSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEIT-YSISERDDN----FPLAVD--PRTGWVQTI-----KPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNT-----RGRFAITSQNGRGLITIAQSLDYKQE-KRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSAS------VFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFS-INPQTG-AIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDK----GSPP----LSSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPD-EGVNAVVHYSIIGG--DDSNAFSLVTRPGSERAQLLTMTE-LDYESTRKRFELVVRAASPPLRNDAHIEILVT--DVNDNAPVLR---DFQVIFNNFRDHFPSGEIGRIPAF------DADVSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSDG 1298 HSP 2 Score: 149.058 bits (375), Expect = 1.180e-35 Identity = 174/698 (24.93%), Postives = 306/698 (43.84%), Query Frame = 3
Query: 558 DINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVD---------ANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF------GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD------STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQ--DETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGR-IFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXY----EIIQG-NEHELFKLNQKSGSLYLMKQPLSND-PEIIRLVVKVSDSGPSPLTNTTIVRI 2549
++ + SP + Q+ V ++ E G+ A+D + SP +VY+ + +Q L +VD A++DRE ++ ++A D PP +G+T L +N+ D ND+SP F E SI+E + + + A D DI N ++ + ++ F I+ ++G I + LD + ++Y L + D + A + VKV ++NDN P S + V + E+ ++ +A + ATD D + + GG S+ D + L KPLD E+ ++ I+ QD G P + T + + V+D ND P F + + E VPV + ++ A D D G N+++ Y I D+ ++D TG ++T DRE+ G + + +V D S+++ + + ++D+ND P F +YE ++ E P V +V A D D ++ ++ Y + T + + S +GR + T +SLD + ++ A DSG + +V + I D N+ P + ++ S ++ + VG V V+ A DSD G+N+ + Y E I G + F +N ++G++ + PL + L V D G L++TT V I
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSP---------------------VVYSMVSLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETS-DSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFS-----ERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSID---SMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQ--------VVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDS---RLHYEI------TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVH--INITDANNFAPIFENAP---YSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAI-VTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEI 995 HSP 3 Score: 128.642 bits (322), Expect = 1.891e-29 Identity = 186/714 (26.05%), Postives = 311/714 (43.56%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNS-------QLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXD---SGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFI---DQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVI-------SILPHVNSSNNVLLVEENIQDETAIASL--SATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT-KPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKV-LSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLY----FSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGN-EHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
+S +Q+++ D NDHSP + + +I E + +GS A D D + I Y ++ V + ++ +F I S ++ +++DRE + LL+ A D + S T + + + + D NDN P F + + + E+ + D + + A D D +N + ++ GN+ +S+F I+ +G + + + LDY + V +Y L I+ D ++ T LLV V + NDNAP S+L +V N++ V+ DE A A + S ++ D++ L+V + + T KPLDRE F + +D G PP+ + + I V D ND P F + E P + VT + A+D D +S+L Y I F+I G + ++ +YK E +R L+ T+ S T + + I D N+ AP+F+ Y S+ E + V V A DSD+ +N QI+Y++ + I+ L FS++P T LDRET + ++ A D G + + DV + + D+NDN P + S L +I + VG V + A D D GLN + Y + + E F ++ SG++ K + L D G PL++T V+I
Sbjct: 444 RSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEI-EYGIEAVTDGAGLAQDQEMPIFRIDSRSG---------VISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNT-----QSQFSIDSMSGDVSLVKPLDY-ESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFP-------------------LAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNG----RGLITIAQSLDYKQE-----KRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDV-GVNAQITYSL------NEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAF--KSPL-YQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQI 1101 HSP 4 Score: 67.0106 bits (162), Expect = 1.329e-10 Identity = 62/239 (25.94%), Postives = 113/239 (47.28%), Query Frame = 3
Query: 525 SNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQY----LCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYL-LPIQVTDSTKFAETILLVKVQ 1226
S+ E+QI +ED+ND P + KI + +PE+S +GS A D D N++ Y++ + FS+V ++ QLL + + + + ++ + SPPL H+ I +TD+NDN+PV L + + NNF D + + ++ A D D+SD GN+ N+ +N +G + + L+ + V + + + V+D A+ I+ + V+
Sbjct: 1094 SSTVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGV-NAVVHYSI--IGGDDSNAFSLVTRPGSERA---QLLTMTELDYESTRKRFELVVR----AASPPLRNDAHIEILVTDVNDNAPV----LRDFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRILSGNNANL-----LRLNSSSGGLVLSPQLNTN--VPKFATMEVSVSDGINEAKAIMQLSVR 1311 HSP 5 Score: 58.5362 bits (140), Expect = 4.458e-8 Identity = 61/221 (27.60%), Postives = 98/221 (44.34%), Query Frame = 3
Query: 1818 DRRNLVDSDPTEKVL------SSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI---------IQGNEHELFKLNQKSG 2435
DRR++VDSD K++ + T I R + +++ + +P F++ Y S+ E V +V A D + + + Y+MV S+ F V + TT SLDRE D+H F + A D + + V + D ND+ P + +I TVG V L+A D D G N+ + Y I Q E +F+++ +SG
Sbjct: 319 DRRDIVDSDHRLKIVYHHQEFNDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE----DSPVVYSMV----SLLDSRSQSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQ---FEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSG 528
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 245.743 bits (626), Expect = 9.434e-67 Identity = 253/903 (28.02%), Postives = 428/903 (47.40%), Query Frame = 3
Query: 192 LANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQ-DFDLSRRENLNFQMMKENNFVSLVN-----GKLFVKAD-IDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTL-KYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTY--LLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH---FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS-------------KLPAESRFFEKD--------LVVMICMITVTLIVSGILVVAI-VLLKCKHCYRN-LPGITYQSKEYRHGHPDGQ 2762
LA+ + ++ L F M A+ + VKE + IG+L ++ + D D+ L F+ + + V LV G++ A+ IDRE++C+ + C + V V +I +I+ IEDIND++P++ + I I+IPE++ I SRY +P A D D N I Y L K V+ L + P+ QL+ V ++DRE + + + ED G+PP + + L + ++D+NDN PVF E+++ EN + + + A D D+ N ++ FSF N ++ + F I+ G I VKQ L D+EVN L+ + S+ + ++V V + NDN P I +N N +L+ EN T IA ++ TD D+ + + +L V D ++ + PLD ET + I D G PP T+ ++ I++ D+ND P FP + I E + + K++A+D D G N+ ++Y + F+ID +G+L DREK +Y TV R N + P L S +++I++D ND +P F Y F +PE VG + D+D A + + +I K F + P + + DRE ++F ++A D+G + V + + D+NDN P ++S DL + + G +VT + A+D+D+G+N+ L Y II G+ LF +++ +G++ L ++ ++ D + RLVVKV D G P L +V ++ + VS + P E + D ++V+I +I T+ V ILV+ + L++C+ R+ + + QS E+ + DG+
Sbjct: 3 LASEAHVLVVLFTCLFLMCRAQE--KDYTVKEEQPENVRIGNLRKDLNLNLDPDIKLSSALQFKPVYKTGDVPLVKVEASTGEILTTANRIDREKLCSGVFNEKRCYYEIEVAVLPDEI-FRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIG-INGIQHYELVKSVSEFGLDIIET-----PEGDKWPQLI--VQQSLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTHLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPL--DREVNPVHKLIVLASDGSSTPSRATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCYTDHDVPFRLKPVFND-----QFLLETAAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALIIYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSF--TVIARDN--GTTP----LQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDAD--AGDNAVVTLSIIN--------GKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDAGLMQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL-----VPSNTSPGSVVTRVFAIDNDTGMNAELQYSIIGGSLRGLFTIDKTTGNITLQEKIVAADQGLHRLVVKVKDLGQPESLHAIALVHLFVNDTVSNATFIQEQLRKSLETPLERNIGDNDVTPQTNGYVIVVIAIIAGTMTV--ILVIFVTALVRCRQTPRHKVVQKSKQSGEWVSPNQDGR 862
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 246.128 bits (627), Expect = 1.300e-66 Identity = 252/903 (27.91%), Postives = 428/903 (47.40%), Query Frame = 3
Query: 192 LANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQ-DFDLSRRENLNFQMMKENNFVSLVN-----GKLFVKAD-IDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTL-KYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTY--LLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS-------------KLPAESRFFEKD--------LVVMICMITVTLIVSGILVVAI-VLLKCKHCYRN-LPGITYQSKEYRHGHPDGQ 2762
LA+ + ++ L F M ++ + VKE + IG+L ++ + D D+ L F+ + + V LV G++ A+ IDRE++C+ + C + V V +I +I+ IEDIND++P++ + I I+IPE++ I SRY +P A D D N I Y L K V+ L + P+ QL+ V ++DRE + + + ED G+PP + + L + ++D+NDN PVF E+++ EN + + + A D D+ N ++ FSF N ++ + F I+ G I VKQ L D+EVN L+ + S+ + ++V V + NDN P I +N N +L+ EN T IA ++ TD D+ + + +L V D ++ + PLD ET + I D G PP T+ ++ I++ D+ND P FP + I E + + K++A+D D G N+ ++Y + F+ID +G+L DREK +Y TV R N + P L S +++I++D ND +P F Y F +PE VG + D+D A + + +I K F + P + + DRE ++F ++A D+G + V + + D+NDN P ++S DL + + G +VT + A+D+D+G+N+ L Y II G+ LF +++ +G++ L ++ ++ D + RLVVKV D G P L +V ++ + VS + P E + D ++V+I +I T+ V ILV+ + L++C+ R+ + + QS E+ + DG+
Sbjct: 3 LASEAHVLVVLFTCLF--LMCRAQEKDYTVKEEQPENVRIGNLRKDLNLNLDPDIKLSSALQFKPVYKTGDVPLVKVEASTGEILTTANRIDREKLCSGVFNEKRCYYEIEVAVLPDEI-FRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIG-INGIQHYELVKSVSEFGLDIIET-----PEGDKWPQLI--VQQSLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTHLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPL--DREVNPVHKLIVLASDGSSTPSRATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCYTDHDVPFRLKPVFND-----QFLLETAAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALIIYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSF--TVIARDN--GTTP----LQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDAD--AGDNAVVTLSIIN--------GKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDAGLMQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL-----VPSNTSPGSVVTRVFAIDNDTGMNAELQYSIIGGSLRGLFTIDKTTGNITLQEKIVAADQGLHRLVVKVKDLGQPESLHAIALVHLFVNDTVSNATFIQEQLRKSLETPLERNIGDNDVTPQTNGYVIVVIAIIAGTMTV--ILVIFVTALVRCRQTPRHKVVQKSKQSGEWVSPNQDGR 862
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 231.106 bits (588), Expect = 5.918e-62 Identity = 231/789 (29.28%), Postives = 374/789 (47.40%), Query Frame = 3
Query: 273 FQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFV-KADIDRERI--CTKKNQCCCLNLFVIVYNLKIQSN---YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSI-VYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT---YLLPIQVTDSTKFAETILLVKVQNENDNAPVISI--LPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLS-RVLTDLSV--VTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF-PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKL 2576
++V E LIG L + + D + + ++ V G +F + IDRE + C K + C L V V +L IQ+ E +I ++DIND++P + + +++PE++ +G+ + +PLA D D+ N ++ YTL + LF + V +K L QL+ V ++DRE + +L + A D G+PP S L + I D NDN+P F K E + EN+ I + Q+ A D D+ N ++ ++ +++ + I+ +G I+VK LD +E+N Y++ S K ++T + + V ++NDNAP + I + V S+ V + E++ TA+A + +D D + +G + R +D SV KY + T PLD E ++ I D G P +T + +QV D ND +P F P + +E P E V ++ ASD D G N++LVY I F ID N+G +R S DRE Y+ T D+ P+ + ++T +I+V+ D ND P F Y FS+ E P VG V +D D E N Q+ + ++P K F + + S DRE ++F ++A D G V V + + D NDN P + S+ I ++ +V V++A D DSG N+ L Y I GN H+LF ++ +G + L K+ + RLV+KVSD G +V IY + ++ +
Sbjct: 27 YRVHEEQPPSTLIGSLAADQGLPDTGHLYKLEVGAPYLR----VDGKTGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDL-IQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTE-RNGVADYTLT-AGPEAVALFGLQVAEDRGEK--LPQLI--VLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPK-LLRIDRSSGIIYVKGPLDR-EEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVV-EVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADK-----GVPSHRG-TATVVIKVL--DRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMD-EGENAQVQ--LSVEPDVGK-------FVIQNGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNSSF-IRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNETIANV 782 HSP 2 Score: 60.8474 bits (146), Expect = 1.031e-8 Identity = 71/242 (29.34%), Postives = 105/242 (43.39%), Query Frame = 3
Query: 1881 RVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGR----IFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEH--ELFKLNQKSGSLYLMKQPLSNDPEI--IRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPA 2582
R+ ++DIND P F S+PE + LA D D E N Y + P ++ V+ D SLDRE D + +I+A D G S + V I D NDN P++ SS + +G V +KA DSD G N + Y + Q + +L ++++ SG +Y+ K PL + EI ++ V D GPSP ++ T V I + PA
Sbjct: 118 RIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTER-NGVADYTLTAGP----EAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSS---YEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYV-KGPLDRE-EINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPA 349
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 232.261 bits (591), Expect = 5.986e-62 Identity = 231/789 (29.28%), Postives = 374/789 (47.40%), Query Frame = 3
Query: 273 FQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFV-KADIDRERI--CTKKNQCCCLNLFVIVYNLKIQSN---YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSI-VYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT---YLLPIQVTDSTKFAETILLVKVQNENDNAPVISI--LPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLS-RVLTDLSV--VTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF-PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKL 2576
++V E LIG L + + D + + ++ V G +F + IDRE + C K + C L V V +L IQ+ E +I ++DIND++P + + +++PE++ +G+ + +PLA D D+ N ++ YTL + LF + V +K L QL+ V ++DRE + +L + A D G+PP S L + I D NDN+P F K E + EN+ I + Q+ A D D+ N ++ ++ +++ + I+ +G I+VK LD +E+N Y++ S K ++T + + V ++NDNAP + I + V S+ V + E++ TA+A + +D D + +G + R +D SV KY + T PLD E ++ I D G P +T + +QV D ND +P F P + +E P E V ++ ASD D G N++LVY I F ID N+G +R S DRE Y+ T D+ P+ + ++T +I+V+ D ND P F Y FS+ E P VG V +D D E N Q+ + ++P K F + + S DRE ++F ++A D G V V + + D NDN P + S+ I ++ +V V++A D DSG N+ L Y I GN H+LF ++ +G + L K+ + RLV+KVSD G +V IY + ++ +
Sbjct: 27 YRVHEEQPPSTLIGSLAADQGLPDTGHLYKLEVGAPYLR----VDGKTGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDL-IQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTE-RNGVADYTLT-AGPEAVALFGLQVAEDRGEK--LPQLI--VLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPK-LLRIDRSSGIIYVKGPLDR-EEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVV-EVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADK-----GVPSHRG-TATVVIKVL--DRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMD-EGENAQVQ--LSVEPDVGK-------FVIQNGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSNSSF-IRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNETIANV 782 HSP 2 Score: 60.8474 bits (146), Expect = 1.154e-8 Identity = 96/345 (27.83%), Postives = 142/345 (41.16%), Query Frame = 3
Query: 1605 ITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSI-FDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTII----------RVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPD-GRIFT---TKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEH--ELFKLNQKSGSLYLMKQPLSNDPEI--IRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPA 2582
I ++ D+G+P + KL +VG + +D TG + T I DRE T+ D RN E +S T +I R+ ++DIND P F S+PE + LA D D E N Y + P ++ V+ D G SLDRE D + +I+A D G S + V I D NDN P++ SS + +G V +KA DSD G N + Y + Q + +L ++++ SG +Y+ K PL + EI ++ V D GPSP ++ T V I + PA
Sbjct: 39 IGSLAADQGLPDTGHLYKL-----EVGA----------PYLRVDGKTGDIFTTEIPIDRE---------TLKDCRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTER-NGVADYTLTAGP----EAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSS---YEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYV-KGPLDRE-EINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPA 349
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh1a4 (protocadherin 1 alpha 4 [Source:ZFIN;Acc:ZDB-GENE-050202-4]) HSP 1 Score: 229.565 bits (584), Expect = 1.001e-61 Identity = 206/707 (29.14%), Postives = 347/707 (49.08%), Query Frame = 3
Query: 198 NLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNF----VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSI---------FDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYE------FSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG--PITHRVSVDVVVKIEDLND 2246
NLS+ + F I++ + + V E + G +IG++ ++ +I +L R FQ+M N V++ G LFVK IDRE +C NQ C LNL + N + ++I I D+ND++PV+ S ++++ E++ G R+ LP+AKDLD N++ Y L S + FS+ +S Y +L + +DREK I L+L A D G PP +G+ + +N+ DINDN PVF K L ++ +KEN + + + A+DLD N ++ +SF N ++ ++F IN +G+I V+ +D++++ + L +Q +D +K +L++V +ENDNAP I P + S V+E+ + TA+A ++ +D D I + G + S Y++++ PLDRE+ + TI D+G PP ++ +I + + D ND PHF A + ++ E VTK+ A D D G N++L Y + + S T ++ NS+ F+ E+T ++ + ++ +D LSS + V I D ND +PV + E +IP + +V + A D+D N +SY + T+ + L+ S G I T + D + H I ++G ++ S+DVVV +E L+D
Sbjct: 2 NLSESVGFFILLLLSLLKFSIGQTSYSVSEEANKGTVIGNIAKDLKISAQELESRM---FQIMPGLNAKYFDVNVKTGSLFVKDRIDREELC-GVNQKCALNLEALAQN---PHRLYRLEIVIVDVNDNAPVFPNSTYILSVTENAIEGDRFPLPVAKDLDVG-SNALKDYKL-----SSNEHFSLDVHSGQRSIYAELILQKA---LDREKQAVIHLILTAIDGGKPPKSGTLSIVVNVKDINDNKPVFSKSLYKVKVKENTPVGTKIISVSARDLDEGINSEIQYSFLGHGNNDELNRFTINTNSGEITVQGQIDHEED-SAIELRVQASDKGSPSKSTHCKVLIEVVDENDNAPEIVTTPLMES------VKEDAKSGTAVALVTVSDKDMGKNGILHCALKGSFPFK---LETSYNNHYSLVVDGPLDRESVSQYNITITAADEGTPPLSSSTVITVHISDVNDNAPHFSAPVINAFLSENSQAGGLVTKVTADDSDTGENAELSYSLLDSSSSSIPVTTLININSLSGEIFSLQSFNHEETKRFQFQ--------VMATDTGVPPLSSNATVNVFILDENDNSPVILAPYSEPGSVNTENIPYSAEAGYFVAKIRAVDAD-SGYNALLSYHL------TEPKGTNLFRIGSSTGEIRTKRRMSDND-LKTHPQIITVSENGEPSLSATTSMDVVV-LESLDD 665 HSP 2 Score: 118.242 bits (295), Expect = 1.902e-26 Identity = 171/682 (25.07%), Postives = 291/682 (42.67%), Query Frame = 3
Query: 888 HLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDND----KLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLL--PIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXG---GLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH-FSID---ENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDI----EAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG--PITHRVSVDVVVKIEDLNDNFP----QWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIY-------FHSEVSKLPA-ESRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRNLPGITYQSKEYRHGHPDGQSSPTAS----DMFSSAVKLSSDVPLY 2828
L I I D+NDN+PVF +S+ EN AKDLD+ N KL+ + S+++ + ++ +++ LD +++ +L+ I K ++V V++ NDN PV S S + V+EN T I S+SA D+D S G +L+R + I + +D E + + ++ D G P + T + I+V+D+ND P + E + V + SD D+G N L + + F ++ N L + DRE +Y + T D LSS+T+I V I D+ND AP F + E S V V A+DSD E + + P T +I+ L G IF+ +S + E F + A D+G P++ +V+V I D NDN P +S + NI G V ++A+D+DSG N+ L+Y + + LF++ +G + ++ ND + ++ VS++G L+ TT + + + ++P E F + +L ++I +++V++ I ++++V L CYR + + HPDG S + S D+ S+ + SDV ++
Sbjct: 112 RLEIVIVDVNDNAPVFPNSTYILSVTENAIEGDRFPLPVAKDLDVGSNALKDYKLSSNEHFSLDVHSGQRSIY----AELILQKALDREKQAVIHLILTAIDGGKPPKSGTLSIVVNVKDINDNKPVFS------KSLYKVKVKENTPVGTKIISVSARDLDEGINSEIQYSFLGHGNNDELNRFTIN---TNSGEITVQGQIDHEEDSAIELRVQASDKGSPSKSTHCKVLIEVVDENDNAPEIVTTPLMESVKEDAKSGTAVALVTVSDKDMGKNGILHCALKGSFPFKLETSYNNHYSLVVDGPLDRESVSQYNITITAADEGT--------PPLSSSTVITVHISDVNDNAPHFSAPVINAFLSENSQAGGLVTKVTADDSDTGENAELSYSLLDSSSSSIPVTTLININSL------SGEIFSL-QSFNHEETKRFQFQVMATDTGVPPLSSNATVNVF--ILDENDNSPVILAPYSEPGSVNTE-NIPYSAEAGYFVAKIRAVDADSGYNALLSYHLTEPKGTNLFRIGSSTGEIRTKRRMSDNDLKTHPQIITVSENGEPSLSATTSMDVVVLESLDDIKTSFREVPVKEESFSDLNLYLLIAIVSVSV----IFLLSLVGLIAAKCYRTDSSFSRYGAPVINTHPDGSWSFSKSTQQYDVCFSSDTIKSDVVVF 758 HSP 3 Score: 86.6557 bits (213), Expect = 1.002e-16 Identity = 137/541 (25.32%), Postives = 229/541 (42.33%), Query Frame = 3
Query: 1005 AKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYD------QEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYR-IDHAH------FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIK--DINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIK-PYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHE-----LFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSE 2564
AKDL IS + + F M + F +N K G +FVK +D + Q+ L + + I++V V NDNAPV +S +L V EN + A D+D S + S S + ++L K LDRE + D G PP+ T I + V D ND P F ++ V + E PV + + ++A D D G+NS++ Y + H + F+I+ N+G + D E+ +L D+ + S +T +V+I+ D ND AP S+ E + V V D D+ N + A+ P++ ++ + ++S+ DG LDRE+ ++ +I A D G S + V I D+NDN P +S ++ ++ G LVT + A DSD+G N+ L+Y ++ + L +N SG ++ ++ + + + V +D+G PL++ V ++ E
Sbjct: 43 AKDLKISAQELESRMF-QIMPGLNAKYFDVNVKTGSLFVKDRIDREELCGVNQKCALNLEALAQNPHRLYRLEIVIVDV---NDNAPVFP------NSTYILSVTENAIEGDRFPLPVAKDLDVGSNALKDYKLSSNEHFSLDVHSGQRSIYAELILQKALDREKQAVIHLILTAIDGGKPPKSGTLSIVVNVKDINDNKPVFSKSLYKVKVKENTPVGTKIISVSARDLDEGINSEIQYSFLGHGNNDELNRFTINTNSGEITVQGQIDHEEDSAIELRVQASDKGSP----------SKSTHCKVLIEVVDENDNAPEIVTTPLMESVKEDAKSGTAVALVTVSDKDM-GKNGILHCALKGSFPFKLETSYNN-HYSLVVDG-------PLDRESVSQYNITITAADEGTPPLSSSTVITVHISDVNDNAPHFSAPV---INAFLSENSQAGGLVTKVTADDSDTGENAELSYSLLDSSSSSIPVTTLININSLSGEIFSLQSFNHEETKRFQFQVMATDTGVPPLSSNATVNVFILDE 551
BLAST of Protocadherin vs. Ensembl Xenopus
Match: ENSXETT00000047798.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 233.032 bits (593), Expect = 2.190e-62 Identity = 230/854 (26.93%), Postives = 398/854 (46.60%), Query Frame = 3
Query: 279 VKEHSEIGLLIGDLVENYRIQ-DFDLSRRENLNFQMMKENNFVSLV-----NGKLFVKAD-IDRERICTK---KNQCCCLNLFVIVYNLKIQSNYF---EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH---FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-----SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEII-RLVVKVSDSG-PSP---------LTNTTIVRIYFHSEVSKLPAESRFFE-----------KDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRN 2705
V+E +LIG+L+++ + D DLS L F+++ + V L+ G++F ++ IDRE++C+ +N+C F V + F +I+ IEDIND+SP++ + I I+IPE++ + SRY +P A D D N I Y L N +F + P+ QL+ V ++DRE+ + + + ED G+P + + L + +TD+NDN PVF + E++I E+ + + Q+ A D D+ N K+ F FGN + + F I+ G I VK+ LD ++ L + S+ + + + + + NDN P I +N N + + E T IA ++ TD D + + +L V + ++ + PLD E+ + I D G PP + ++ I++ D+ND P F + + E P + +TK++A+D D G N++L Y + F++D TG+L DREK Y D N P+ L + T + + + D ND +P F Y F +PE VG + D+D N ++ ++V ++ F + P + + DRE ++F ++A D G +V V + +ED+NDN P + ++S DL + + G +V + A+D+D+G+N+ L Y II GN LF + ++SG++ L ++ L+ D ++ +LV+KV+DSG P P N TI + E+ + E+ E D V +I I + +++ L++C+ R+
Sbjct: 30 VREELPENVLIGNLLKDLNLTLDPDLSTP--LQFKLVYKTGDVPLIRVEENTGEIFTTSNRIDREKLCSGIFTENKC-----FYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGV-NGIQHYELLKGQN----VFGLDVIETPEGDKWPQLI--VQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDVPFRLKPVFDN-----QFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGN-----PS---LQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDAD-SGENAVVTLSLV---------NARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYDL-----VQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPEPFHTIAFVHLFVNETITNGSYIQELVRKSKETAVGEDFRDGEITPQTNDYVKIIIAIIAGTMTVILVIFVTALVRCRQTPRH 841
BLAST of Protocadherin vs. Ensembl Xenopus
Match: ENSXETT00000047804.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 232.646 bits (592), Expect = 2.636e-62 Identity = 230/854 (26.93%), Postives = 398/854 (46.60%), Query Frame = 3
Query: 279 VKEHSEIGLLIGDLVENYRIQ-DFDLSRRENLNFQMMKENNFVSLV-----NGKLFVKAD-IDRERICTK---KNQCCCLNLFVIVYNLKIQSNYF---EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH---FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-----SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEII-RLVVKVSDSG-PSP---------LTNTTIVRIYFHSEVSKLPAESRFFE-----------KDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRN 2705
V+E +LIG+L+++ + D DLS L F+++ + V L+ G++F ++ IDRE++C+ +N+C F V + F +I+ IEDIND+SP++ + I I+IPE++ + SRY +P A D D N I Y L N +F + P+ QL+ V ++DRE+ + + + ED G+P + + L + +TD+NDN PVF + E++I E+ + + Q+ A D D+ N K+ F FGN + + F I+ G I VK+ LD ++ L + S+ + + + + + NDN P I +N N + + E T IA ++ TD D + + +L V + ++ + PLD E+ + I D G PP + ++ I++ D+ND P F + + E P + +TK++A+D D G N++L Y + F++D TG+L DREK Y D N P+ L + T + + + D ND +P F Y F +PE VG + D+D N ++ ++V ++ F + P + + DRE ++F ++A D G +V V + +ED+NDN P + ++S DL + + G +V + A+D+D+G+N+ L Y II GN LF + ++SG++ L ++ L+ D ++ +LV+KV+DSG P P N TI + E+ + E+ E D V +I I + +++ L++C+ R+
Sbjct: 50 VREELPENVLIGNLLKDLNLTLDPDLSTP--LQFKLVYKTGDVPLIRVEENTGEIFTTSNRIDREKLCSGIFTENKC-----FYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGV-NGIQHYELLKGQN----VFGLDVIETPEGDKWPQLI--VQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDVPFRLKPVFDN-----QFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGN-----PS---LQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDAD-SGENAVVTLSLV---------NARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYDL-----VQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPEPFHTIAFVHLFVNETITNGSYIQELVRKSKETAVGEDFRDGEITPQTNDYVKIIIAIIAGTMTVILVIFVTALVRCRQTPRH 861
BLAST of Protocadherin vs. Ensembl Xenopus
Match: ENSXETT00000047801.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 233.032 bits (593), Expect = 2.797e-62 Identity = 230/854 (26.93%), Postives = 398/854 (46.60%), Query Frame = 3
Query: 279 VKEHSEIGLLIGDLVENYRIQ-DFDLSRRENLNFQMMKENNFVSLV-----NGKLFVKAD-IDRERICTK---KNQCCCLNLFVIVYNLKIQSNYF---EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH---FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-----SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEII-RLVVKVSDSG-PSP---------LTNTTIVRIYFHSEVSKLPAESRFFE-----------KDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRN 2705
V+E +LIG+L+++ + D DLS L F+++ + V L+ G++F ++ IDRE++C+ +N+C F V + F +I+ IEDIND+SP++ + I I+IPE++ + SRY +P A D D N I Y L N +F + P+ QL+ V ++DRE+ + + + ED G+P + + L + +TD+NDN PVF + E++I E+ + + Q+ A D D+ N K+ F FGN + + F I+ G I VK+ LD ++ L + S+ + + + + + NDN P I +N N + + E T IA ++ TD D + + +L V + ++ + PLD E+ + I D G PP + ++ I++ D+ND P F + + E P + +TK++A+D D G N++L Y + F++D TG+L DREK Y D N P+ L + T + + + D ND +P F Y F +PE VG + D+D N ++ ++V ++ F + P + + DRE ++F ++A D G +V V + +ED+NDN P + ++S DL + + G +V + A+D+D+G+N+ L Y II GN LF + ++SG++ L ++ L+ D ++ +LV+KV+DSG P P N TI + E+ + E+ E D V +I I + +++ L++C+ R+
Sbjct: 50 VREELPENVLIGNLLKDLNLTLDPDLSTP--LQFKLVYKTGDVPLIRVEENTGEIFTTSNRIDREKLCSGIFTENKC-----FYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGV-NGIQHYELLKGQN----VFGLDVIETPEGDKWPQLI--VQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDVPFRLKPVFDN-----QFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGN-----PS---LQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDAD-SGENAVVTLSLV---------NARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYDL-----VQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPEPFHTIAFVHLFVNETITNGSYIQELVRKSKETAVGEDFRDGEITPQTNDYVKIIIAIIAGTMTVILVIFVTALVRCRQTPRH 861
BLAST of Protocadherin vs. Ensembl Xenopus
Match: ENSXETT00000027070.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:19099783:19110965:-1 gene:ENSXETG00000013163.1 transcript:ENSXETT00000027070.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 224.942 bits (572), Expect = 3.847e-60 Identity = 234/836 (27.99%), Postives = 393/836 (47.01%), Query Frame = 3
Query: 267 LQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRE-NLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETI-LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI---------DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSIN----ITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAE-------------SRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCK 2690
LQ+ + E +G +IG++ + + +LS R+ ++ + K+ V L NG L+V IDRE +C + Q C LN+ + ++ +++ I + I+D+ND+SP +++S I+I E + +G+ + L AKD D +NSI Y L S F ++ D +L+L + +DREK L+L A D G+P TG++ + I +TDINDN P+F K +++ EN I + + A D D N ++T+ F N + + F IN +NG + + LDY+ N Y + ++ D LL++V + NDNAP I I + ++ E+ + T IA ++ D+D+ S L + S Y ++ + LDRE + TIK +D G P +K I + + D ND P F YI E P + +++A+D D+ N ++VY I ++ SI+ +GVL FD EK E+ ++A D L++ IR+I+ D+ND APVF+K+ Y I E + V A DSDI N ++ Y ++ E S Y S++ + + S D E+ + A DSG + + V + I D NDN P+ + S + + I T G LVT + A+D+DSG N+ L+Y ++Q + + Q +G + + + D R+VV V D+G L++T + + ++ E + F+ LV+ I +I++ I + V+ V+ KC+
Sbjct: 34 LQYSIYEEQRLGYVIGNIANDLGVSAEELSSRKFHIVSRSKKQYLNVHLENGDLYVADRIDREALCGMQ-QNCFLNIEAV---MESPLHFYTINVEIQDVNDNSPSFSKSIFEISISELAVVGTHFALGSAKDPDLG-NNSIQSYKL-----SANDYFGMLEKVNTDGRKYPELVL--EKTLDREKKNSSVLILSAFDGGTPSKTGTSLIRIVVTDINDNYPLFNKDTYRVTVSENVPIGFLVIDLHATDADEGSNAEITYLF-NDIPENAQEVFAINPENGSVQITGKLDYEVATN-YEMTVEAKDGGGLVSYCKLLIQVSDVNDNAPDILITSFSD------IIPEDSRVGTVIALVNLDDLDSGENGEVVGQISESLPFHLIS---SSGNYYKLVTSMDLDREKTSEYNITIKAEDKGSPQLTNSKTIRLILTDVNDNAPVFDKMDYVAYIQENNPSGNSFYRVHATDPDINENGKVVYMILTDIIEDIPISSYVSINTVSGVLYAQRSFDYEKLREFYIQA----------EDKGSPQLTNNKTIRLILTDVNDNAPVFEKMDYVAYIQENNPSGSSFFRVHATDSDINE-NGKVVYMILTDIIEDMPLSS--YISINTVSGVLYAQRSFDYESLREFYIQVMAKDSGSPSRSANATVKICITDQNDNAPKILYPSQDSEAASVFEFIPHFSTKGYLVTKVVAVDADSGHNAWLSYHLLQVPDPSFLIIGQNTGEIRITRDLQETDALRQRIVVMVKDNGYPMLSSTVTLNLVVAENFQQVLPEITNQHIDTESSSNATFY---LVISIALISILFIFT---VLVAVISKCR 827
BLAST of Protocadherin vs. Ensembl Xenopus
Match: vapa (VAMP associated protein A [Source:Xenbase;Acc:XB-GENE-990155]) HSP 1 Score: 214.542 bits (545), Expect = 2.541e-56 Identity = 205/732 (28.01%), Postives = 350/732 (47.81%), Query Frame = 3
Query: 402 VSLVNGKLFVKAD-IDRERICTKKNQC----CCLNLFVIVYNLKIQSNYF---EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD-STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVV--TKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI--DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFP-QWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIY 2552
VS G++F + IDRE++C + C L V++ + +++F +I+I ++D ND++P++ + I I+IPE++ I SR+ +P A D D+ N + Y L N Q +F + P+ QL+ V N+DRE+ + + + ED G+P + + L + ++D+NDN PVF + E+ I EN I + Q+ A D DI N ++ + FG + + F +N G I V++ LD +E + L + TD S+ A + + V + NDN P I + ++ N + + E T IA ++ +D D V L V +Y + + LD E + F I D G P T ++ +++ D+ND P F + + + E ++T ++ASD D G NS +VY++ + + F +D TGVL + +FDRE+ + T D + P L S + V + D ND +P F ++F + E VG + A DSD N+ ++ + ++ E F + P + + S DRE ++F ++A D G + V + I D NDN P S S+ + + G +V + A+D+D+G+N+ L Y I+ GN LF+++ +G++ L ++P + D + RLVV +SD G P PL +V +Y
Sbjct: 78 VSSSTGEIFTTSTRIDREKLCAGSSNSDENECFFELEVVI----LPNDFFRLIKIKIIVKDTNDNAPMFPSTVINISIPENTLINSRFPIPSAVDPDTG-FNGVQHYELL---NGQ-SVFGLDIVETPEGEKWPQLI--VQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNKPVFKESQVEVHIPENAPIGTSVVQLHATDADIGSNAEIKYIFGAQVTSATKRLFALNNTTGLITVQRPLDR-EETAVHKLTVLATDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPINTKIALITVSDKDTDVNSKVICFIE-----REVPFHLKAVYDNQYLLETSSLLDYEGIKEFSFKIVAADTGKPSLNQTALVRVELEDENDNPPIFSQPVIELSVSENNRRGLYLTTVSASDEDSGKNSDIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARD-----NGTPP---LQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITATDSD-AGENKAVTLS-ILNDNEN--------FVLDPYSGLIKSNVSFDREQQSSYTFDVKAVDGGQPPRSSTAKVTINIMDANDNSPVVISPPSNTSFKL-VPLSAIPGSVVAEVFAVDTDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPSAADVGLHRLVVNISDLGYPKPLHTLVLVFLY 773
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 243.817 bits (621), Expect = 6.032e-66 Identity = 226/798 (28.32%), Postives = 366/798 (45.86%), Query Frame = 3
Query: 273 FQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFV-KADIDRERICTKKNQC----CCLNLFVIVYNLKIQSN---YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD---STKFAETILLVKVQNENDNAPVISI--LPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL-----KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID-----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKE---------SLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVS 2570
++V E LIG L +Y + D + + ++ V G +F + IDRE + +NQ C L V + +L +Q+ E QI ++DIND++P + I + IPE++ IGS + +PLA D D+ P N ++ Y L+ +Q +LF + + + Q L V N+DRE+ + +L + +D G+PP S L + + D NDN+P F +P E + EN+ I + Q+ A D D N ++ ++F + + R ++ G I V+ +D ++++T + D + K A ++V V++ NDNAP I I + V + + + E++ +ETA+A + +D D +G + + S +D KY + T PLD E + + I D G PP +T + +QV+D ND P F +IT V E V ++ ASD D G N++LVY ++ F+I G +R + DRE+ Y+L+ DR P+ L T + V + D ND P F Y FS+ E VG V D D K +++ SV D F + S DRE ++F ++A D G V V + + D NDN P + S+ + +T + +G V+ + A D DSG+N+ L Y I GN + LF++ SG++ L K+ + RLVVKVSD G P T +V +Y + ++
Sbjct: 40 YKVPEEQPPNTLIGSLAADYGLPDVGHLYKLEVGAPYLR----VDGKTGDIFTTETSIDREGLRECQNQIPGNPCILEFEVSITDL-VQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGP-NGVASYELQAGPEAQ-ELFGL---QVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVV-RRLLRLDRNTGLITVQGPVDR-EDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSK--KKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADR-----GSPS---LQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGD-------------------KGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRL-LTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLA 795
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 243.817 bits (621), Expect = 6.032e-66 Identity = 226/798 (28.32%), Postives = 366/798 (45.86%), Query Frame = 3
Query: 273 FQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFV-KADIDRERICTKKNQC----CCLNLFVIVYNLKIQSN---YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD---STKFAETILLVKVQNENDNAPVISI--LPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL-----KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID-----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKE---------SLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVS 2570
++V E LIG L +Y + D + + ++ V G +F + IDRE + +NQ C L V + +L +Q+ E QI ++DIND++P + I + IPE++ IGS + +PLA D D+ P N ++ Y L+ +Q +LF + + + Q L V N+DRE+ + +L + +D G+PP S L + + D NDN+P F +P E + EN+ I + Q+ A D D N ++ ++F + + R ++ G I V+ +D ++++T + D + K A ++V V++ NDNAP I I + V + + + E++ +ETA+A + +D D +G + + S +D KY + T PLD E + + I D G PP +T + +QV+D ND P F +IT V E V ++ ASD D G N++LVY ++ F+I G +R + DRE+ Y+L+ DR P+ L T + V + D ND P F Y FS+ E VG V D D K +++ SV D F + S DRE ++F ++A D G V V + + D NDN P + S+ + +T + +G V+ + A D DSG+N+ L Y I GN + LF++ SG++ L K+ + RLVVKVSD G P T +V +Y + ++
Sbjct: 40 YKVPEEQPPNTLIGSLAADYGLPDVGHLYKLEVGAPYLR----VDGKTGDIFTTETSIDREGLRECQNQIPGNPCILEFEVSITDL-VQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGP-NGVASYELQAGPEAQ-ELFGL---QVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVV-RRLLRLDRNTGLITVQGPVDR-EDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSK--KKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADR-----GSPS---LQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGD-------------------KGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSHRL-LTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLA 795
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 234.572 bits (597), Expect = 4.916e-63 Identity = 222/811 (27.37%), Postives = 383/811 (47.23%), Query Frame = 3
Query: 183 METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDF-DLSRRENLNFQMMKENNFVSLV-----NGKLFVK-ADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH---AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEV 2567
M+ L+ F + L V F + + + V+E +LIGDL+++ + D S + F+++ + V L+ G++F A IDRE++C + C + V V +I +I+ IEDIND++P++ + I I+IPE+S I SRY LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++ D NDN P+F++ E+SI EN I + Q+ A D DI +N ++ F F N ++ + F++N G I VK+ LD ++ + LL + + A +LV V + NDN P I I VN +N +L+ EN T IA ++ D D+ + + +L V ++ ++ + LD E+ + + D G PP + ++ I+V D+ND P F + ++ + E + +TK++A+D D G N+++ Y + F++D+ TG+L DREK +Y TV + N + L S + V + D ND +P+F Y F +PE VG + D D + A+ + + F++ P + S DRE + ++F ++A D G ++ + V + + D+NDN P + S+ + G +V + A+D D G+N+ + Y I+ GN LF + Q SG++ L ++ + +D + R++VK +D G P L N V + + V
Sbjct: 1 MDLLSGTYIFAVLLACVVF---QSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEI-FRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIG-INGVQNYQLIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSN-----QFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYF--TVLAQDNGIPP------LMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGE-----NSAVTLSILDVNDQ-----FTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFEW-VLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESV 776
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 235.343 bits (599), Expect = 1.070e-62 Identity = 222/811 (27.37%), Postives = 384/811 (47.35%), Query Frame = 3
Query: 183 METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDF-DLSRRENLNFQMMKENNFVSLV-----NGKLFV-KADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH---AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEV 2567
M+ L+ F + L V F + + + V+E +LIGDL+++ + D S + F+++ + V L+ G++F A IDRE++C + C + V V +I +I+ IEDIND++P++ + I I+IPE+S I SRY LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++ D NDN P+F++ E+SI EN I + Q+ A D DI +N ++ F F N ++ + F++N G I VK+ LD ++ + LL + + A +LV V + NDN P I I VN +N +L+ EN T IA ++ D D+ + + +L V ++ ++ + LD E+ + + D G PP + ++ I+V D+ND P F + ++ + E + +TK++A+D D G N+++ Y + F++D+ TG+L DREK +Y TV + N + L S + V + D ND +P+F Y F +PE VG + D D N ++ +++ F++ P + S DRE + ++F ++A D G ++ + V + + D+NDN P + S+ + G +V + A+D D G+N+ + Y I+ GN LF + Q SG++ L ++ + +D + R++VK +D G P L N V + + V
Sbjct: 1 MDLLSGTYIFAVLLACVVF---QSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEI-FRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIG-INGVQNYQLIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSN-----QFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYF--TVLAQDNGIPP------LMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDY-GENSAVTLSIL---------DVNDQFTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFEW-VLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESV 776
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 234.187 bits (596), Expect = 1.373e-62 Identity = 222/811 (27.37%), Postives = 383/811 (47.23%), Query Frame = 3
Query: 183 METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDF-DLSRRENLNFQMMKENNFVSLV-----NGKLFV-KADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH---AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEV 2567
M+ L+ F + L V F + + + V+E +LIGDL+++ + D S + F+++ + V L+ G++F A IDRE++C + C + V V +I +I+ IEDIND++P++ + I I+IPE+S I SRY LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++ D NDN P+F++ E+SI EN I + Q+ A D DI +N ++ F F N ++ + F++N G I VK+ LD ++ + LL + + A +LV V + NDN P I I VN +N +L+ EN T IA ++ D D+ + + +L V ++ ++ + LD E+ + + D G PP + ++ I+V D+ND P F + ++ + E + +TK++A+D D G N+++ Y + F++D+ TG+L DREK +Y TV + N + L S + V + D ND +P+F Y F +PE VG + D D + A+ + + F++ P + S DRE + ++F ++A D G ++ + V + + D+NDN P + S+ + G +V + A+D D G+N+ + Y I+ GN LF + Q SG++ L ++ + +D + R++VK +D G P L N V + + V
Sbjct: 1 MDLLSGTYIFAVLLACVVF---QSGAQEKNYTVREEMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDREKLCAGIVLDARCFYEVEVAVLPDEI-FRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRYSLPAAIDPDIG-INGVQNYQLIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSVTQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPSHKLLVLATDGGSTPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFTDHEVPFRLRPVFSN-----QFLLETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDAPPEFNLDQRTGILTAVKKLDREKQEKYYF--TVLAQDNGIPP------LMSNATVFVTVLDQNDNSPIFTHNEYNFYVPESLPKHGTVGLITVTDPDYGE-----NSAVTLSILDVNDQ-----FTIDPQSGVIRPNISFDRERQESYTFYVKAEDGGRVSRSSTARVTINVVDVNDNKPIFIDPPSNYSFEW-VLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQPDSLFNVVNVNFFINESV 776
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q6WYY1|PC11X_PANPA (Protocadherin-11 X-linked OS=Pan paniscus OX=9597 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 249.595 bits (636), Expect = 2.189e-66 Identity = 234/821 (28.50%), Postives = 401/821 (48.84%), Query Frame = 3
Query: 183 METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFV-KADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSAT--DMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-----SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
M+ L+ F + L V F + + + ++E +LIGDL ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ T D D++ + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E +TK++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P + ++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 1 MDLLSGTYIFAVLLACVVF---HSGAQEKNYTIREEMPENVLIGDL-----LKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG-TNGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYELVLP-----STNPGTVVFQVMAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 777
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q71M42|PC11X_PANTR (Protocadherin-11 X-linked OS=Pan troglodytes OX=9598 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 249.595 bits (636), Expect = 2.436e-66 Identity = 234/821 (28.50%), Postives = 401/821 (48.84%), Query Frame = 3
Query: 183 METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFV-KADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSAT--DMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-----SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
M+ L+ F + L V F + + + ++E +LIGDL ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ T D D++ + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E +TK++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P + ++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 1 MDLLSGTYIFAVLLACVVF---HSGAQEKNYTIREEMPENVLIGDL-----LKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG-TNGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYELVLP-----STNPGTVVFQVMAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 777
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q6X862|PC11X_GORGO (Protocadherin-11 X-linked OS=Gorilla gorilla gorilla OX=9595 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 248.825 bits (634), Expect = 4.310e-66 Identity = 235/821 (28.62%), Postives = 401/821 (48.84%), Query Frame = 3
Query: 183 METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFVK-ADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSAT--DMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-----SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
M+ L+ F + L V F + + + ++E +LIGDL ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DREK + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ T D D++ + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E +TK++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P + ++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 1 MDLLSGTYIFAVLLACVVF---HSGAQEKNYTIREEMPENVLIGDL-----LKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG-INGVQNYELIKSQN----MFGLDVIETPEGDKMPQLI--VQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYELVLP-----STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 777
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q6WXV7|PC11X_PONPY (Protocadherin-11 X-linked OS=Pongo pygmaeus OX=9600 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 246.899 bits (629), Expect = 1.698e-65 Identity = 234/821 (28.50%), Postives = 400/821 (48.72%), Query Frame = 3
Query: 183 METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFV-KADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSAT--DMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW-----SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
M+ L+ F + L V F + + + ++E +LIGDL ++D +LS N + F+++ + V L G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ T D D++ + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E +TK++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P + ++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 1 MDLLSGTYIFAVLLACVVF---HSGAQEKNYTIREEMPENVLIGDL-----LKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLTRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG-INGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPINDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYELVLP-----STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 777
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q9BZA8|PC11Y_HUMAN (Protocadherin-11 Y-linked OS=Homo sapiens OX=9606 GN=PCDH11Y PE=1 SV=1) HSP 1 Score: 245.743 bits (626), Expect = 3.821e-65 Identity = 230/812 (28.33%), Postives = 398/812 (49.01%), Query Frame = 3
Query: 210 FIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRREN------LNFQMMKENNFVSLV-----NGKLFVK-ADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSAT--DMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
F + L+ V F + + + ++E +LIG+L ++D +LS N + F+++ + V L+ G++F A IDRE++C +++ C + V + +I +I+ IEDIND++P++ + I I+IPE+S I S+Y LP A D D N + Y L N +F + P+ + QL+ V +DRE+ + + + ED G P + + L +++TD NDN PVF + E+SI EN + + Q+ A D DI +N K+ FSF N ++ R F++N G I +K+ LD ++ N LL + A ++LV V + NDN P I I VN N+ +++ ENI T IA ++ T D D++ + +L V ++ ++ + LD E+ + + + D G PP + ++ I+V D+ND P F + TV I E + K++A+D D G N+++ Y + FS+D TG+L DREK +Y T+ + N V L+S + V I D ND +PVF Y+F +PE VG + D D N ++ +++ + + F++ + S DRE + ++F ++A D G ++ S V + + D+NDN P +++S +L L G +V + A+D+D+G+N+ + Y I+ GN +LF ++Q++G++ LM++ D + R++VK +D G P L + IV ++ + V+
Sbjct: 42 FAVLLVCVVF---HSGAQEKNYTIREEIPENVLIGNL-----LKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEI-FRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG-INGVQNYELIKSQN----IFGLDVIETPEGDKMPQLI--VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-----QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF--TILAKDNGVPP------LTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY-GDNSAVTLSILDENDD---------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLP-----STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVT 809
BLAST of Protocadherin vs. TrEMBL
Match: A0A068WFD5 (Protocadherin 9 OS=Echinococcus granulosus OX=6210 GN=EgrG_000878500 PE=4 SV=1) HSP 1 Score: 361.688 bits (927), Expect = 3.526e-102 Identity = 280/960 (29.17%), Postives = 456/960 (47.50%), Query Frame = 3
Query: 192 LANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSL--VNGKLFVKADIDRERICTKKNQCC-----------------------------CLNLFVIVYN----LKIQSN---YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRY------------TLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYD---------------QEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNS--SNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTK--------YTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYR-------IDH-AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKL----YFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSH--SSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSND----------PEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESR-------------------------FFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCY 2699
+ +++ F + L+++ A+ S+ F + E IG +G L E + D++ R +NF + + V+ +G + V+ IDRE +C + CC + + V+ L QS ++ I + D+ND+ P W+ ++ + IPEH+ IG ++ LP A D D P+N++ Y T++ + + KL S + P Y L L+V+A++DREK LL+A D GSP LTGS + I ITDIND +P F + + I EN + + A D D SD ++L + G++ + E + F I+ + G + V +DY+ + YL+PI+VTD AET L V V N NDN P ISI + S + E+ T +A+++ +D D + + + V + ++ +KPLD ET I C D G P T + + +++ D ND P F A+ I EG+PV + + K++ASD D G +++ YR +D+ + +DE +G +R+ ++FD+E D + + +V ++TT + V+I+DINDC P F+ YEF+I EG ++ VG V A D D + N ++ Y I ET S + + F+++P G ++T +DRE + +FS+ A DSG V+++IED+NDN PQW + SINI+ TVG +V L+A+D D G+N + YEII+GN + F L+ SG+LYL K N+ P L +K +D G P +NT+++RI S + P +S+ + ++DL++MI MI +TL+VS +L++AIVLL+C+ +
Sbjct: 6 ITSIATFTVTLLLLHAAFTDAQKTSVAFVINEELPIGERVGSLTEKLAL---DITSRSEVNFVPLIDLRLVNFNRTSGLITVRQRIDRESLCKETGACCPGRSVIPPPVSTFHDVLLPHLSDVQYPRCAIKMLVMDQRPQTPLSQQSQEHLLIQVVIYVNDLNDNPPAWSPDRLELEIPEHTVIGRKFQLPEAADPDEGPENTVQSYRLIPSDPHDHESTVRGLASDAFKLSSELIERSPGAPYKFALGLKVEADLDREKQSAYYFLLIATDGGSPQLTGSLSVIIRITDINDQTPYFRQTNPSVEILENTAVGTQIYTAVAMDDDPSDANRLEYRMGSTASAEVQRLFSIDSRIGSVVVSGDIDYESAPILPNRDSKDPLFSDDYGYLIPIEVTDQAHIAETKLRVHVLNTNDNPPTISIQSPLQRSISKGEFYIHEDAPVGTLVATITMSDADEKTGSERGFPNRASIPYCSTTNTFFTVQPLHSAMRNLFKLVTSKPLDHETKSTHGVMIVCHDAGQPVLSTKQYLTVRLEDVNDSPPVFEKAVYYARISEGLPVHTPILKIHASDADSGEAAEVRYRFVSSGRQMDYDSMVLLDEKSGQIRSGAVFDQESIKSINFTVEAVDCASGNGTSCGGRVNTATTEVIVLIEDINDCPPEFEHQSYEFTIEEGHVSKVPVGKVHATDRDADGKNNRVRYQ--INDEETSSLLEGIQPSRLFTITPTGELYTNSVPIDREQIPLLTFSVVAMDSGEPPLSAFATVIIRIEDVNDNGPQWVYPPPGPQAASINISAYSTVGMVVARLEAIDLDIGVNGQIEYEIIRGNSQKYFDLDHLSGTLYLTKALEVNNGNNSMNEQAAPSSFALSLKATDGGDPPRSNTSLLRIIVQS-IEAFPLDSQSADLVGTGGKNQHFSSNSYFKQQSGYVDRDLLIMIVMIIITLLVSVLLIMAIVLLRCRQIH 959
BLAST of Protocadherin vs. TrEMBL
Match: A0A068Y9F6 (Protocadherin 9 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000878500 PE=4 SV=1) HSP 1 Score: 357.836 bits (917), Expect = 6.728e-101 Identity = 283/962 (29.42%), Postives = 458/962 (47.61%), Query Frame = 3
Query: 192 LANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSL--VNGKLFVKADIDRERICTKKNQCC-----------------------------CLNLFVIVYN----LKIQSN---YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRY------------TLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYD---------------QEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNS--SNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTK--------YTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYR-------IDH-AHFSIDENTGVLRTNSIFDRE--KTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKL----YFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSH--SSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSND----------PEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLP-------------------------AESRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCY 2699
+ +++ F + L+++ A+ S+ F + E IG +G L E + D++ R +NF + + V+ +G + V+ IDRE +C + CC + + V+ L QS ++ I + D+ND+ P W+ ++ + IPEH+ IG ++ LP A D D P+N++ Y T+ + + KL S + P Y L L+V+A++DREK LL+A D GSP LTGS + I ITDIND +P F + + I EN + ++ A D D SD ++L + G++ + E + F I+ + G + V +DY+ + YL+PI+VTD AET L V V N NDN P ISI + S + E+ T +A+++ +D D + + + V + ++ +K LD ET I C D G P T + + +++ D ND P F A+ I EG+PV + + K++ASD D G +++ YR +D+ + +DE +G +R+ ++FDRE K+ + +EA N + +V ++TT + V+I+DINDC P F+ YEF I EG ++ VG V A D D + N ++ Y I ET S + + F+++P G ++T +DRE + +FS+ A DSG V+++IED+NDN PQW + SINI+ TVG +V L+A+D D G+N + YEII+GN + F L+ SG+LYL K N+ P L +K +D G P +NT+++RI S + P +S + ++DL++MI MI +TL+VS +L++AIVLL+C+ +
Sbjct: 6 ITSIATFTVTLLLLHAACTDAQKTSVAFVINEELPIGERVGSLTEKLAL---DITSRSEVNFVPLTDLRLVNFNRTSGLITVRQRIDRESLCKETGACCPGRSVIPPPVSTFHDVLLPHLSDVQYPRCAIKMLVMDQRPQTPLSQQSQEHLLIQVVIYVNDLNDNPPAWSPDRLELEIPEHTVIGRKFQLPEAADPDEGPENTVQSYRLIPSDPHDHESTVHGLASDAFKLSSELIERSPGAPYKFALGLKVEADLDREKQPAYYFLLIATDGGSPQLTGSLSVIIRITDINDQTPYFRQTNPSVEILENTAVGTHIYTAVAMDDDPSDANRLAYRMGSTASAEVQRLFSIDSRIGSVVVSGDIDYESAPILPNRDSKDPLFSDDYGYLIPIEVTDQAHIAETKLRVHVLNTNDNPPTISIQSPLQRSVSKGEFYIREDAPVGTLVATITMSDADEKTGSERGFPNRASIPYCSTTNTFFTVQPLHSAMRNLFKLVTSKSLDHETKSTHGVMIVCHDAGQPVLSTKQYLTVRLEDVNDSPPVFEKAVYYARISEGLPVHTPILKIHASDADSGEVAEVRYRFVSNGRQMDYDSMVLLDEKSGQIRSGAVFDRESIKSINFTVEAVDCASGNRISCG--GRVNTATTEVIVLIEDINDCPPEFEHQSYEFIIEEGHVSKVPVGKVHATDRDADGKNNRVRYQ--INDEETSSLLEGIQPSRLFTITPTGELYTNSVPIDREQIPLLTFSVVAMDSGEPPLSAFATVIIRIEDVNDNGPQWVYPPPGPQAASINISAYSTVGMVVARLEAIDLDIGVNGQIEYEIIRGNSQKYFDLDHLSGTLYLTKALEVNNGNNSMNEQAAPSSFALSLKATDGGDPPRSNTSLLRIIVQS-IEAFPLDIQSPDLVSTSGKNQHFSSNSYFKQQSGYVDRDLLIMIVMIIITLLVSVLLIMAIVLLRCRQIH 959
BLAST of Protocadherin vs. TrEMBL
Match: A0A1I8IPY5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 338.576 bits (867), Expect = 6.194e-95 Identity = 247/798 (30.95%), Postives = 397/798 (49.75%), Query Frame = 3
Query: 420 KLFVKADIDRERICTKKNQCC-----C-LNLFVIVYNLKIQSNYFEI---QISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYN-SLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPP-LTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLL----VEENIQDETAIASLSATDMDNXXXXXXXX------XXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGV-PVESFV-TKLNASDCDVGVNSQLVYRIDHA---HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHE----LFKLNQKSGSLYLMKQ--PLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAES---------RFFEKDLVVMICMITVTLIVSGILVVAIVLLKCK 2690
K F K+ IDRE +C++ CC C L+L +IV++ EI + + D+ND++P W ++ + +PEHS +GSR+ LP+A D D +P+N+ RY L S L F + Y + P L L + A++DRE + L+A D G P LTGS + I+++DINDN P F + + + EN+ + + L ++ A D D SD ++L F G S + F ++ + G ++ + LDY +E +Y +P+ VTD A+ + ++V NENDN P I+++ + EN T +ASL D D+ +S A + G L L + S + ++ + DRE F I C D+G P +V + ++ I + D+ND TP F V + E P+ +FV K+ A D D G N++L Y +D A HF ID T + FDRE ++ L D +L D + + + T ++ I+D+NDC P F Y F++ E + Y+G+V A D D E +R++ Y M+ P S ++ YF V+ DGR++T + +DRE + +F + A D R + V V I D+NDN PQW S +N++ ++ +GR V L+ D D G N S+ Y + H+ LF + + G + L Q P + + +RL + +D G P ++ + I V + P E R + +L +++ M+ VT+IVS L+ AIV L+C+
Sbjct: 235 KCFQKSKIDRESLCSEVGACCPEAPDCKLSLSIIVFDKSQPGKVREIVRLDLRVVDLNDNAPRWNSPRLSLEVPEHSPVGSRFQLPVAMDPDKAPENATQRYELV----SGLDKFQLGYLLADPAGRQAGSLWLEIRADLDREVAAWHQAELVAVDGGHPAALTGSLTVNISVSDINDNPPRFGRFPRLVKVAENSPLSRELLRLNATDADDSDMERLRFRLGVSASQSVAEMFRVDKRTGSVWAMRTLDY-EERKSYDIPVTVTDGKHSADASVRIEVVNENDNPPKITLVSFGGGGGGSSSGNFELAENAAFGTTVASLDVFDADDKEESLSVACYVEPPTEFGILPLYK-----SAKRNFLVVSNRAFDREQTPSFTVRISCNDNGTPNRVDSVVMRIDIRDENDNTPEFLQNPLFVLLPENKDPLPAFVLAKMEARDADSGDNAELRYSLDAASSRHFDIDRGTAAIWARRSFDRELEQQFNLTVFATDLGDLPDVEGRRRTATGTVVVN--IEDVNDCPPEFSASHYAFAVEENAELTRYLGNVTASDCDAEERHRRVVYRMLGGPSGPDSQLAFNYFRVTQDGRVYTGSQPIDREFRESFTFLVLADDQA--GRRQTAHVTVSILDINDNSPQWVFPSSDTQQVNVSVQQPIGRPVARLRTKDPDYGPNGSVVYSL---ESHQPPTRLFSVTPE-GEILLSGQINPARDLGQFVRLRIVAADRGQPPRSSWANLTIRI---VERAPDEGGGGFFGSSPRTADGNLAIILAMVVVTVIVSIFLIAAIVFLRCR 1011
BLAST of Protocadherin vs. TrEMBL
Match: A0A267DUI6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021969g1 PE=4 SV=1) HSP 1 Score: 327.405 bits (838), Expect = 7.238e-92 Identity = 268/892 (30.04%), Postives = 437/892 (48.99%), Query Frame = 3
Query: 210 FIIFLIVVDFPMKMAKSIS---LQFQVKEHSEIGLLIGDL-----VENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQCC------C-LNLFVIVYNLKIQSNYFE----IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVI---SILPHVNSS-----NNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVT-KYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTK----LNASDCDVGVNSQLVYRID----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLY-FSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSN-DPEIIR-LVVKVSDSG-PSPLTNTTIVRIYFHSEVSK--LPAESRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRNLPGITYQSKEYRHGHPDG 2759
++ +L V +++A S + L+ E G + DL ++ R D +L R E + ++ FV G++F KA IDRE +C + CC C L + + + + F+ + + + D+ND++P WT +++ I EH+ +GS++ LP A D D +PDN+ Y L S LF +V PD LLL V ++DRE +++ A D G PLTGS + +++TDINDN P F +SI EN +++ L ++ A D D SD + L + F S + F ++ ++G I + LDY+ + Y +P+ V+D ET + V++ N NDN P I SILP S ++ L + EN T IAS+ D D+ + + +L +L ++ I+ P DRE QAT+ C D+G P + + I+V+D+ND P F I + E E+ +TK + A D D GVN+ + Y +D HA F ID TG + FDREK + + TV+ +++ DS TE ++T + V I+D+NDC PVF++ Y F++ E R +VG V A D D E +R I Y ++ +P + S+L+ F VSPDG ++T+ ++LDRE HS+S+ + + + + DLNDN P+W + +NI+ ++VG V L A D D G N ++ Y ++ ++ + ++G L L + + N D ++ LV D G P L + + I+ + + E +L++++ M+ +TL+VS +L+ AI L+C C R S E ++G G
Sbjct: 12 YLAWLFVCSLFIELAASQTSFFLRHSFVEEQPSGAKLADLRHLLQLQGGRRGDANLDRCEFQPLDIREKYFFVDSKTGEIFAKARIDRESLCEEAVTCCKGINPDCKLPMTIGMVDPTRSGPAFQEILQVDLDVLDLNDNAPRWTSPTLLLEISEHTLVGSKFKLPPADDPDKAPDNTTQIYRLA----SGTDLFRVVPVFSPDPAVSVVLLLEVLVDLDRETKPFHTIVIHAVDGGPVPLTGSVTVNVSLTDINDNPPFFTHESRTVSIPENYPLEKELFRVTASDRDASDIENLHYRFSLSASKAVLDDFRVDRRSGSIVAVRPLDYESK-REYSIPVTVSDGKHLVETTIEVRLLNINDNPPTITVKSILPEQQPSASGAQSSDLFIRENAPIGTLIASVDVKDADDKAMQETVTCFIEPSRLFGMLPLYEAARHQFKIVSNVPFDRELKSMHQATVTCHDNGSPNRDASVQNRIRVIDENDHPPTFRERIVEAQLHEN--AETSMTKPVIRMEAGDKDEGVNAAIRYSLDTQSEHA-FYIDTLTGAIYPKFSFDREKISQVNI--TVF-AKDMGDSSDTELQFTATGTVVVNIQDVNDCDPVFQQRHYSFAVVENVPNRTFVGKVRATDCDAEERHRSIVYRLIRQPGDP----SQLFPFEVSPDGSVYTSTDNLDREA--RHSYSLRVLADDQADRSDTATMSIAVLDLNDNAPRWVYPGGTAPRVNISMHKSVGDTVYKLHASDPDEGNNGTVVYSLVSVQPYDSLFVVSRAGDLTLGRSIVFNRDVNLLHNLVFNACDQGSPRQLFSVKSMSIFITEQAPNNYGLGSPKTSEGNLIIIVAMVVITLVVSIVLIAAIFFLRCNFCDRRT-----HSTERQNGRVKG 881
BLAST of Protocadherin vs. TrEMBL
Match: A0A564YH37 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS5814 PE=4 SV=1) HSP 1 Score: 324.709 bits (831), Expect = 2.157e-90 Identity = 283/963 (29.39%), Postives = 457/963 (47.46%), Query Frame = 3
Query: 255 KSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSL--VNGKLFVKADIDRERICTKKNQCC-----------------------CLNLFVIVY---NLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTL-------------KYVNNSQLKLFSIVY--NSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSP-PL----TGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYD----------------------QEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNV--LLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVT----------KYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHF-SIDENTGVLRTNSIFDREKTGEYKLEATVYD------RRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKS----------HISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQW---SHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLS---------ND-------------PEIIRLVVKVSDSGPSPLTNTTIVRI---------YFHSEVSKLPAESR-------------FFEKDLVVMICMITVTLIVSGILVVAIVLLKCKH 2693
+ IS+ F + E G LIG L+E + LS ++ F + + ++ L +G+LFV++ IDRE +C + CC L+L VI Q I +I DIND+ P W+ + I IPEHS IG+ LP A D D +++ RY L + N + + + SI +S LN L L++++++DRE+ ++ LLL+A D GS P+ TG+ ++ + +TDIND +P F + I I E+ + M AKD D SD +L + F + + E F I K G I + Q LDY+ +EV Y++P++VTD F++ L V+++N NDNAP I++ H+ N LL+ E++ T IA+++ D D + GG S+ T T +Y ++ ++PLDRET TI C D G P + I + D ND P F + I E +P + + K+ A+D D+G+N+ + Y I D +D +G + + ++FDREK D ++ +++ + +S ++I ++I+D+NDC P F + YEF + EG P+ VGSV A DSD + N +I Y++ +S + + F+++ +G I+T +DRE + SF++ A D G + +VV++++D+ND+ P W SS + + N++ TVGR + LKA+D+DSG N + Y II+GNE E F L++ SG+LYL KQ +S N+ P+ L +K SD G +P +NTTI++I S+ ++ SR ++DL+++ MI V LI+S +L+ AIV L+C+
Sbjct: 28 QGISVIFPLAEEQPPGTLIGSLIEKLGPK---LSSPSSVLFTPLGQERYIRLNQTSGQLFVRSRIDREALCEQVGTCCTSSSKSQNAFSHAFENDDPNPDCALHLLVIDQRDPGSSTQPKLVHIIFNIVDINDNPPKWSPDTLEIEIPEHSPIGTTIQLPEATDPDQCIESAPIRYELIPQIESTSGFSNHESRNIADMFMLSITPTDSSFGASQKLN-LQLKINSDLDRERRDQYRLLLIATDGGSKNPVFGDRTGTLNIIVKVTDINDQAPYFPEEHPTIEISEDVEPRTRIFTMIAKDDDPSDATRLVYRFASMASGEVMRLFSICEKTGTITLNQELDYEVAPLLPDSRSSNSLYNSQGDKAKEVG-YIIPVRVTDGVHFSQAELRVRLKNVNDNAPNITVQSHLPRWRNTNDLLLSEDVAVGTMIATITMEDADERWMDNKLGTG-GGYSESQCETAHPFFTVQPLYPTARYQYMLVTSRPLDRETKSTHTITIACHDSGQPVLSRGVHVVIHLEDLNDSPPVFSQVLYQSKISENLPFNTLIEKVQATDSDIGLNAAIRYGIKSDVDLGDLVKLDPMSGQIYSATVFDREKMESINFTVIAMDCAGGAMNKSEINNGCSIIHTASASVI-IMIEDVNDCVPEFDQNNYEFVVKEGQRPQQSVGSVHATDSDADIKNSRIQYSISESEELQQSDHPGSVNNEGYRASSLFAITSNGEIYTRNLPIDREKTPVLSFTVIASDFGHPSLSAFANVVIRVQDVNDHSPVWIFPQSSSSIIVRANMSSHATVGREIAHLKAIDADSGPNGEIEYTIIKGNEQEFFALDKASGTLYLAKQLISIPKHPSADQNETAPTNLQNQDELTPQSFTLALKASDKGITPRSNTTILKIDVIQNQRGDRTTSQYNQYKGTSRHTGNLISRSGFGMIGDRDLMIITAMIVVALIISFVLIAAIVFLRCRQ 983
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 252.677 bits (644), Expect = 1.520e-68 Identity = 248/872 (28.44%), Postives = 408/872 (46.79%), Query Frame = 3
Query: 213 IIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLV-----NGKLFVKAD-IDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS-------------KLPAESRFFEKDL--------VVMICMITVTLIVSGILVVAI-VLLKCKHCYRN 2705
+I +V K +++ + E+ IG L DL N D ++ L F+ + + V LV G++F A+ IDRER+C+ + C + V V +I +I+ IEDIND++P++ + I I+IPE++ I +RY +P A D D N I Y L V + L I P+ QL+ V N+DRE + + + ED G+PP + + L + ++D+NDN PVF E+++ EN + + Q+ A D D+ N ++ FSF N ++ + F I+ G I VKQ LD + L+ + S + ++V V + NDN P I +N N +L+ EN T IA ++ TD D + + +L V D ++ + PLD ET + I D G PP T+ ++ I++ D+ND P FP + I E + + K+ A+D D G N+ ++Y + F+ID +G+L + DREK +Y TV R N S+P L S +++I++D ND +P F Y F +PE VG + D+D A + I +I K F + P + + DRE ++F ++A DSG I V + + D+NDN P ++S DL + G +VT + A+D+D+G+N+ L Y II G+ LF +++ +G++ L ++ + D + RLVVKV D G P L + +V ++ + VS + P + + D+ +V+I +I T+ V ILV+ + L++C+ R+
Sbjct: 12 LILTCLVSLCWAQEKDYTVKEEQPENVRIGNLRTDLDLNL---DPNIKLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLCSGVFNEKRCFYEIEVAVLPDEI-FRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVG-INGIQHYELVKVGALEFGLDII---ETPEGDKWPQLI--VQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRLKPVFND-----QFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSF--TVIARDN--GSNP----LQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDAD--AGDNAIVTLSIIN--------GKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL-----VPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIALVHLFVNDTVSNATFLQEQVRKSMETPLDKNVGDSDILPQTNGYVIVVIAIIAGTMTV--ILVIFVTALVRCRQTPRH 843
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 251.136 bits (640), Expect = 2.207e-68 Identity = 246/871 (28.24%), Postives = 407/871 (46.73%), Query Frame = 3
Query: 213 IIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLV-----NGKLFVKAD-IDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTL-KYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS-------------KLPAESRFFEKDLVVMI--CMITVTLIVSGILVVAIV-----LLKCKHCYRN 2705
+I +V K +++ + E+ IG L DL N D ++ L F+ + + V LV G++F A+ IDRER+C+ + C + V V +I +I+ IEDIND++P++ + I I+IPE++ I +RY +P A D D N I Y L K V+ L + P+ QL+ V N+DRE + + + ED G+PP + + L + ++D+NDN PVF E+++ EN + + Q+ A D D+ N ++ FSF N ++ + F I+ G I VKQ LD + L+ + S + ++V V + NDN P I +N N +L+ EN T IA ++ TD D + + +L V D ++ + PLD ET + I D G PP T+ ++ I++ D+ND P FP + I E + + K+ A+D D G N+ ++Y + F+ID +G+L + DREK +Y TV R N S+P L S +++I++D ND +P F Y F +PE VG + D+D A + I +I K F + P + + DRE ++F ++A DSG I V + + D+NDN P ++S DL + G +VT + A+D+D+G+N+ L Y II G+ LF +++ +G++ L ++ + D + RLVVKV D G P L + +V ++ + VS + P + + D++ +I V I++G + V +V L++C+ R+
Sbjct: 52 LILTCLVSLCWAQEKDYTVKEEQPENVRIGNLRTDLDLNL---DPNIKLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLCSGVFNEKRCFYEIEVAVLPDEI-FRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVG-INGIQHYELVKSVSEFGLDIIET-----PEGDKWPQLI--VQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRLKPVFND-----QFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSF--TVIARDN--GSNP----LQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDAD--AGDNAIVTLSIIN--------GKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL-----VPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIALVHLFVNDTVSNATFLQEQVRKSMETPLDKNVGDSDILPQTNGYVIVVIAIIAGTMTVILVIFVTALVRCRQTPRH 882
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 251.521 bits (641), Expect = 4.587e-68 Identity = 248/873 (28.41%), Postives = 409/873 (46.85%), Query Frame = 3
Query: 213 IIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLV-----NGKLFVKAD-IDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTL-KYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS-------------KLPAESRFFEKDL--------VVMICMITVTLIVSGILVVAI-VLLKCKHCYRN 2705
+I +V K +++ + E+ IG L DL N D ++ L F+ + + V LV G++F A+ IDRER+C+ + C + V V +I +I+ IEDIND++P++ + I I+IPE++ I +RY +P A D D N I Y L K V+ L + P+ QL+ V N+DRE + + + ED G+PP + + L + ++D+NDN PVF E+++ EN + + Q+ A D D+ N ++ FSF N ++ + F I+ G I VKQ LD + L+ + S + ++V V + NDN P I +N N +L+ EN T IA ++ TD D + + +L V D ++ + PLD ET + I D G PP T+ ++ I++ D+ND P FP + I E + + K+ A+D D G N+ ++Y + F+ID +G+L + DREK +Y TV R N S+P L S +++I++D ND +P F Y F +PE VG + D+D A + I +I K F + P + + DRE ++F ++A DSG I V + + D+NDN P ++S DL + G +VT + A+D+D+G+N+ L Y II G+ LF +++ +G++ L ++ + D + RLVVKV D G P L + +V ++ + VS + P + + D+ +V+I +I T+ V ILV+ + L++C+ R+
Sbjct: 52 LILTCLVSLCWAQEKDYTVKEEQPENVRIGNLRTDLDLNL---DPNIKLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLCSGVFNEKRCFYEIEVAVLPDEI-FRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVG-INGIQHYELVKSVSEFGLDIIET-----PEGDKWPQLI--VQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRLKPVFND-----QFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSF--TVIARDN--GSNP----LQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDAD--AGDNAIVTLSIIN--------GKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL-----VPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIALVHLFVNDTVSNATFLQEQVRKSMETPLDKNVGDSDILPQTNGYVIVVIAIIAGTMTV--ILVIFVTALVRCRQTPRH 882
BLAST of Protocadherin vs. Ensembl Cavefish
Match: ENSAMXT00000036470.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:10716691:10726912:1 gene:ENSAMXG00000037804.1 transcript:ENSAMXT00000036470.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 240.736 bits (613), Expect = 2.352e-65 Identity = 249/913 (27.27%), Postives = 434/913 (47.54%), Query Frame = 3
Query: 201 LSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMM--KENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYN-LKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNG-------KIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILL---VKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXX--XXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH-FSID---ENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG--PITHRVSVDVVVKIEDLNDN----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKL-PA-------ESRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRNLPGITYQSKEYRHGHPDGQSSPTAS----DMFSSAVKLSSDVPLY 2828
L F++ ++ + + S + + V E + G ++G++ ++ I DL R F+++ +++ VSL G LFV IDRE +C+ +C +++ + N LK+ F I++ I DIND++P++ SK ++NI E S +G ++ LPLA+D D+ N++ Y L S + FS+ + D + +L + +DRE I L+L A D G PPL+G+T + I I D+NDNSPVF + L ++ +KEN + + A DLD N ++T++ + F +N ++G ++ +++ LD +++ L+ + D + + L + V + NDN P S + S V EN T + L+ATD+D S G K + + S+ + T+ PLDRE F+ + QD G P+ + + I+VLD ND P T + E + V + +D D+G N ++ ++ F++ +N L N DRE +Y + ++ +D LSS+ ++ V I D+ND AP F + F + E S + +V A+D D+ N QI Y+++ + S +S + ++P +K+S + E F ++A DSG P++ V+V+V I D NDN P +S + L NI G V ++A+D+DSG N+ L+Y I + + LF++ SG + ++ ND + LV+ V D G L+ T V + + + P+ E F +L ++I +++V++ I +++++ L CYR+ + S HPDG S + S D+ S+ L SDV ++
Sbjct: 8 LMDFVVIVLFLPLLLWNLSSGQIVYSVSEEVKAGTVVGNVAKDLNINVQDLEARM---FRIVSSRKSFDVSLKTGALFVTDRIDREALCSTIKKCS-MHIEAMAQNPLKL----FRIEVHIMDINDNAPLFPVSKQILNITELSAVGEKFTLPLAEDPDTG-SNAVKNYKL-----SPNEYFSLNVQNGEDSGSVELVLQKA---LDRETQSVIHLILTAIDGGKPPLSGTTEIAILILDVNDNSPVFSQSLYKVKVKENAAFGTKVLSLSATDLDEGLNSEITYAIIRQGTLSANEYFSLNVQSGGEQNISPQLVLQKALDREKQATVQLI-LTALDGGRPHRSGTLDLSINVIDVNDNTPAFSKEMYKVS------VLENTLPGTPVIKLNATDLDAGLNGEIVYSLISHGKEKWADIFAINSITGEITV--KGPLDREDTAAFELHAQAQDKGSSPRASHCKVLIEVLDVNDSPPVISVTSLTSTVREDATTGTAVGLITIADNDIGKNGEVSAKVKGTGPFALQASYKNYYSLVVNGPLDREDMPQYSV--------TILATDKGTPPLSSSIVLAVDIADVNDNAPRFSDIVTVFYVKENSPSGNIIATVTAQDPDVNE-NAQIVYSLINRKNMDSSWMSMV--DINPVSGDIYSKQSFNYEEVKSFQFKVQATDSGAPPLSSNVTVNVF--IVDENDNRPVILPPYSEAGSLNTE-NIPYSAEAGYFVGKVRAIDADSGYNALLSYHITEPKGNNLFRIGSSSGEIRTKRRMSDNDLKTHPLVITVCDHGEPSLSATVSVDVVVAESMDSVRPSLREVQIKEDNFSNLNLYLLIAIVSVSV----IFLLSLIALIAAKCYRSDDPFSRCSPPVVTTHPDGSWSYSKSTQQYDVCFSSDTLKSDVVVF 876
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 228.024 bits (580), Expect = 7.056e-61 Identity = 212/815 (26.01%), Postives = 390/815 (47.85%), Query Frame = 3
Query: 210 FIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLS--RRENLNFQMMK---ENNFVSLVN--GKLFVKAD-IDRERIC---TKKNQCCCLNLFVIVYNLKIQSNYF---EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTK------YTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI--DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN-----FPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS 2570
+++ +V + A + L + ++E + +LIG++ ++ I + + NL ++++ +N + +++ G++F ++ IDRE++C + ++ C + V++ + ++YF +I+I ++D ND++P++ I I+IPE++ I SR+ +P A D D P NS+ +Y L VN IV P+ QL+ V N+DRE+ + + + ED GSP + + L + +TD+NDN PVF + E+ I E++ + + Q+ A D D+ N ++ + FG ++ R F +N G I V++ LD ++ N L + S+ A + + V + NDNAP I + ++ +N +L+ E T IA ++ +D D + G + + D+ K Y + + LD E + + I D G P T ++ +++ D+ND P F + + + E + ++T + A+D D G N+++VY++ + + F +D TGVL + +FDRE + T D + L S + V I D ND +P F ++F + E VG + D+D A + ++ E F + P + + S DRE ++F + A DSG + V + + D+NDN +P + S L + G +V + A+D D+G+N+ L Y I+ GN LF+++ +G++ L ++P D + RLVV +SD G P L +V +Y ++ V
Sbjct: 7 YLLATLVACLWLDPAIAQELIYPIREELQENVLIGNIPKDLNISHMNTATGASNNLVYRLVSKAGDNPLLRVMSNTGEIFTTSNRIDREKLCPGPSYEDSECSFEIEVVI----LPNDYFRLIKIKIVVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDMGP-NSVYKYEL--VNGQSAFGLDIV--ETPEGEKWPQLI--VQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGLITVQRPLDREETANHKLSVLASDGSSSSARATVTINVTDVNDNAPNIDLRYIISPTNGTVLLSEKDPVNTKIALITVSDKD---------TDVNGKVICFIEKDVPFHLKAVYDNQYLLETSALLDYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGT--------RALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD--AGENAVVSLSILNDNEN--------FILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPSNTSFKL-----VPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVNGNNKGLFRIDPVTGNITLEEKPTEADSGLHRLVVNISDLGYPKSLHTLVLVFLYVNNTVG 778
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 209.534 bits (532), Expect = 5.520e-56 Identity = 228/819 (27.84%), Postives = 369/819 (45.05%), Query Frame = 3
Query: 264 SLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNF--VSLVNGKLFVKADIDRERICTKKNQCCCLNLFV----IVYNLKIQSN----YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKL--FSIVYNSLPDKTYL----------NQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTE-ISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSM-NIEDRSKFYINGKNGKIFVKQILDYDQE-VNTYLLPIQVTDSTKF---AETILLVKVQNENDNAPVISILPHVNS--SNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLS-RVLTDLSVVTKYTILL--TKPLDRETNEFFQATIKCQDDGYPPQVTTKIIN--IQVLDKNDCTPHF--PA------AITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH--------FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKL------FYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFP---------QWSHSSDLGLSINITREETVGRLVTV-LKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPS 2519
+L ++V E +G +IGDL ++ + +++ + + V+ ++G+L V +DRE +C ++ C F+ + K Q + ++Q+ + DINDH+P + + ++I E +G R LP A D D+ NSI Y + + L+L FS+V + D ++ LL + +DRE + ELLL ED G+P L+GS LTI + D NDN+PVF+ P T + I E++ + + Q+ A D D N + +SF + ++ ++ +++G G + V+ D+E + + L + D + A + V++ ++NDNAPV ++ + + + EN+ T + +S +D D S+ ++L +L+ K LL T+ LD E + + ++ D G P +K++N I V+D ND TP F PA A+ V + E P + V L A+D D G N + + + FS++ TG L + DREK Y+L D P K + I+RV + D ND AP F + Y+F + E +S YVG+V D D E N +++ +V ++ + + G + T LDRE + S+ A DSG S V + + D NDN P W H + G LV V + A D D+G N YEII GN +F LN SG+L L + S D + RLVV+V D G S
Sbjct: 28 ALLYEVDEEVLVGYVIGDLRQSNLLCVCFFPPAPHVSPLPLHTPSLCIVNELSGELSVALRLDREALCMEEPDACRSTGFMHTVQVAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAG-TNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVD------VRLEFPTGAELASPNKVQFLLKTTRLLDYEEAQQYNVSVLAADRGTPK--LSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACD-----GGSPQRK---ARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLD-EGDNARVALNLV-----REAGPDWIGGAGDTPGGVVRTLVVLDREDRVQYELSVRAVDSGRPALSASCRVSITVSDTNDNAPVITSPNTNDTWKH---------VRTFSPAGMLVGVSVTANDIDAGDNGRPLYEIIGGNPKGIFLLNADSGALSLARTVSSLDEGLHRLVVRVRDRGGS 814
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 202.986 bits (515), Expect = 1.161e-53 Identity = 206/778 (26.48%), Postives = 353/778 (45.37%), Query Frame = 3
Query: 252 AKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMM---KENNFVSLVN-----GKLFVKA-DIDRERICTKKNQCCCLNLFVIVYNLKIQSNYF----EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF-----GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD---STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG 2513
A+ + ++V E G IG+ + R+ D++L L +++M E+ LV G+LF +DRE +C ++ ++ V V L +Q F E++I++EDIND++P + + +++PE++ G R+ + A D DS N + RY L + + + F + + + L++R ++DRE+ + E+ L A D GSPP +GS L IN+TD NDNSPVF + + I EN+ + ++ Q+ A D D N ++ + G + F ++ +G + V +L+ +E Y + I TD A + V V + NDN+P I I V N V+ + E +A ++ +D D + ++ L L+ +Y + + LD ET + IK D G T + I++LD ND P F V + E + + ++A+D D+ N+++VY + F +D TG++ DREK Y ++ D VL + V + D+ND P F ++F + E VG V DSD E N ++ +++ ++ FS+ P+ + + DRE + ++A D G +V VV+ + D+NDN P + G +VT + A+D+D+ +N+ L Y I+ GN H LF ++ G++ LM+ + RLVV+VSD G
Sbjct: 34 AEEFKVSYRVAEELREGAFIGNPSVDLRLADYNLE----LTYKVMLSKAEDAAPPLVRVNPRTGELFAAGRKMDREALCGGQDPGDECHVDVQVGVLPVQPGPFFKLIEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEA-NGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVR--KSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNR-EESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPD-IGANGAVTCYIYNPEVPFQLKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPTMFHMDPETGIISLTEQLDREKKANYSF--------TILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVPKHSTVGMVTVADSD-EGENGRVRLSIL-------GTDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSPIVLMPPSNTTYKFVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGNPHNLFHIDPVIGNITLMEPLTETHHGLHRLVVRVSDIG 786 HSP 2 Score: 56.225 bits (134), Expect = 3.806e-8 Identity = 58/224 (25.89%), Postives = 98/224 (43.75%), Query Frame = 3
Query: 1878 IRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGR---IFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNE--------HELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGP 2516
+R+ ++DIND AP F S+PE + A D D EA N Y ++ T S +L + + +G ++SLDRE ++ ++ A D G H S + + + D NDN P + + +++ I VG V L A D D+G N+ + Y + LF+L+Q SG + + + + R+++ +D GP
Sbjct: 139 VRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEA-NGVRRYELLPSDPATVSAF-ELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAE---VNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGP 357
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: si:ch211-199f5.1 (protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]) HSP 1 Score: 176.022 bits (445), Expect = 2.675e-45 Identity = 174/679 (25.63%), Postives = 307/679 (45.21%), Query Frame = 3
Query: 258 SISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNF----VSLVNGKLFVKADIDRERICTKKNQC-------CCL--NLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT-YLLPIQVTD---STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXG--GLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA---------HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPV-----FKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLD--RETYDMHSFSIEAWDSG 2189
+I++++ + E G L+G L ++ + + ++ + +F++M+ ++F V +G + + IDRE+ C + C C L LF +V+ ++ + DINDH+P + +S++ + I E +G+R L A+DLD N++ Y L + + F + + D +L+ V + +DRE+ + L L A D G PP +G+T + I + D NDNSPVF + ++++E+ L + A D+D N ++ +SF + ++ E R F ++ K GK+ +K LD+ E+N+ Y + IQ D S+ A +LV V++ NDNAP I + + S + + V E E+ + ++ +D+D++ + G KL L Y ++ LDRE + ++ D G PP+V + +++LD+ND P F + + E ++VT + A D D N + Y + + + SI+ ++G + D E + D D P L + + V I D ND APV + +P + V V A DSD EA N ++SY +V I++L G +FT S+ + HS + D G
Sbjct: 28 AITVKYALYEEQPAGTLVGRLSDDLQGR---VAEHPSRHFRLMRRDDFSLVHVEEADGTVSAREVIDREQQCGQAPSCVIRFDVLCTLPRGLFQLVH----------AEVELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVG-GNALRAYHLD-----ENERFGLALRARTDGAKYAELV--VKSRLDREQEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQTSCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGKLSLKGQLDH--ELNSEYEISIQARDMGPSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLRGHPHFKL------LPYRDDYVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTSLTFQVQARD-----DGVPP---LVTNATVSVRIVDENDNAPVVTHPPLRNGTGVVRLPRDAGLGYLVTVVRARDSDSEA-NGELSYRIVQGNERNLFRINRL------GGEVFTNAASVTDAAASATRHSLVVMVRDRG 662 HSP 2 Score: 157.147 bits (396), Expect = 2.630e-39 Identity = 175/620 (28.23%), Postives = 279/620 (45.00%), Query Frame = 3
Query: 888 HLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYING-KNGKIFVKQILDYDQEVNTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLS-RVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKI-INIQVLDKNDCTPH------FPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-DHAHFSI--DENTGVLRTNSIFDREKTGEY--KLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSH---SSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEII---RLVVKVSDSGPSPLTNTTI--VRIYFHSEVSKLPAESRFFEKD-LVVMICMITVTLIVSGILVVA 2669
H + + DIND++P F + + I E+ + + A+DLD+ N + + + +G K ++ VK LD +QE Y L + D + T++ + V + NDN+PV + +S NV V E+ T + +L+ATD+D S S + R L L T + L LD E N ++ +I+ +D G P + + + V D ND P + TV++ EG ESFV + SD D N + + H HF + + V+ TNS DRE+ +Y LEA+ D +V + +R++ D ND P F + YE S+ E +SP YV +V A D+D E N I+Y +V E Y S++P LD E +F ++A D G + V V+I D NDN P +H + G+ + + R+ +G LVTV++A DSDS N L+Y I+QGNE LF++N+ G ++ +++ LVV V D G L+ T +R+ H + E++ + L VM L ++ +++VA
Sbjct: 121 HAEVELLDINDHAPDFARSEMHVEISESVALGTRVPLEGARDLDVGGNALRAYHLDENERFGLALRARTDGAKYAELVVKSRLDREQE-GEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFA-----QTSCNVT-VREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTG-KLSLKGQLDHELNSEYEISIQARDMG-PSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLRGHPHFKLLPYRDDYVVVTNSSLDREQMADYFLVLEAS--------DGGTPPRVAARQFTVRLL--DENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEH-NGMIAYNVV--ESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTSLTFQVQARDDGVPPLVTNATVSVRIVDENDNAPVVTHPPLRNGTGV-VRLPRDAGLGYLVTVVRARDSDSEANGELSYRIVQGNERNLFRINRLGGEVFTNAASVTDAAASATRHSLVVMVRDRGSPALSATAAIEIRVGAHGDGDDGADETQPLDASMLAVMALGAACALTLAAVVLVA 717
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 162.54 bits (410), Expect = 1.514e-40 Identity = 175/678 (25.81%), Postives = 295/678 (43.51%), Query Frame = 3
Query: 537 EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD---NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID--HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTE-KVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIY 2552
++ + + D+ND+ PV+ + +I E+ G+ A D D + ++ RY L + ++ ++ ++ + RV ++DRE+ +L + A D G +TI + D D P F + + EN + + A LD++ N G+ R F I G+IF +D +++ Y L + E + V V + N++APV +S V + E+ + + S+ ATD D N +GG K + D + +Y LDRET E + T+ D G P ++ +N+ VLD ND P F ++ + E V S V + A+D D G N + Y + +F +D TG + + +FDRE A+ ++V +D K L ++V ++D+ND P F K Y+ S+ E +S + V A D D E +N + YA+ K F+V T SLDRE ++ + A DSG S V V++ D NDN P+++ S LS++ VG L+ L A D D+G + + Y I+ GN H F +++ +GS++L ++ + RL V D G P ++ TI+ ++
Sbjct: 539 KVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTV-RYQLTAGDAARFQVNAVT----------GAVSTRV--SLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNANVTYLIVSGDQ-----RGSFSIEWSGGRIFTANAIDREEQA-FYQLRVVANSGGVAGEASVSVLVHDVNNHAPVFD-----RASYEVSIAEDEPVN-SRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFG-IFPDGQLYVRYE------LDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASF--SFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVD-EGVNGALRYAINEGNEGGK-------FTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESL---LSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVH 1171 HSP 2 Score: 152.91 bits (385), Expect = 1.384e-37 Identity = 197/744 (26.48%), Postives = 329/744 (44.22%), Query Frame = 3
Query: 423 LFVKADIDRERICTKKNQCCCLNLFVIVYNLKI----------QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD--STKFAETI-LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGG--LKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG--PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXY--EIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIR--------LVVKVSDSG-PSPLTNTTIVRIYFH 2558
L V + +DRERI +YNL I +S + + + D+NDH+P + S + E + GS A D DS N+ RY++ V+ + L FS+ D++ L+ D +DRE + L + A+D G+ P T T LT+ + D+ND P+F + + EN+ ++ + A D D+ +N + ++F M + R F ++ GK+ + LD +E+ Y L +Q D S T + V V + NDN PV + + S + EN TA+ +++ATD D + + G + +V T+ + LDRE +Q + D G+ + I+ I V D D P F + + E V + V ++AS D +N+ + Y I FSI+ + G + T + DRE+ Y+L ++ + V++ D+N+ APVF + YE SI E SV A D D N ++ YE F + PDG+++ E LDRET + +S ++ A D+G P++ V+V+V V D+NDN P ++ SS + + E+ VG LV ++A D+D+G N + Y E Q N F+L+ ++G + ++ + + +IR V +D G P PL + V+++
Sbjct: 292 LKVASQLDRERIP--------------MYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGL-NAKLRYSI--VSGNDLGWFSV------DES---TGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDR-EELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFAS------ILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTRVS------LDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLD--LNANVTYLIVSGDQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVA-----------NSGGVAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKD-SGKNGEVK-------YEIGEGNGGEKFGIFPDGQLYVRYE-LDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVL--DVNDNKPLFNSSSYV---FHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVN----FELDSETGRIASLR--VFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQ 963 HSP 3 Score: 151.754 bits (382), Expect = 2.953e-37 Identity = 156/588 (26.53%), Postives = 262/588 (44.56%), Query Frame = 3
Query: 537 EIQISIEDINDHSPVWTQSKIV-INIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYV-NNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISIL---PHVNSSNNVLLVEENIQDETAIASLSATDMDN-XXXXXXXXXXXGGLKLSRVLTDLSVVTKYTIL-LTKPLDRETNEFFQATIKCQDDGYP-PQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFP 2255
E+++ + D+ND++P + + ++ + E + +G + L A D D P N ++ + K V N + +L + + + +L+ L +DRE L + AED GSP G + + + D NDN P F KP S+ E++ + L +DL L F + K G + +Q LD++ Y L ++ D ++++ + NDN P I + P S++ V+E+ T A ++ TD D+ ++ S GG + + V +L + LDRE + TI D+G P + T + + V D ND P F + + EG P S+V + A D D G+N++L Y I D FS+DE+TG++ T+ DRE L N+ D + ++ T + V + D+ND P+F + Y + E S P ++V SV A DSD+ N + Y P + + +++ S G++ TT +SLDRE + + ++A D G + V V + DLNDN P
Sbjct: 8 EVRVVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGP-NGVNHHAYKIVSGNEEGRL--VPPRPVTKRAFLH---LATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAAL-----RDLLHRGRGPLAVPF--------------DPKTGMVSTRQPLDFEAR-RQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSAS----VDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDESTGLVTTDGKVDREVASSVVL--------NISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDL-GENGTVRYNF--DP-DMPAQYREMFRLDSLTGKV-TTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHP 552 HSP 4 Score: 144.05 bits (362), Expect = 8.107e-35 Identity = 169/683 (24.74%), Postives = 294/683 (43.05%), Query Frame = 3
Query: 333 RIQDFDLSRRENLNFQMMKENN---FVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSP-PLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVE--ENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH-----AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKK----LFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRET----YDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETV 2315
R D D + + +++ + N F +G+L+V+ ++DRE + L + + ++ S+ + +++ D+ND+ P++ S V + E ++GS A D D+ + ++ K N +L + SL + + + L+R + ++A D G P PL + + + D+NDN P F K + + S+ E+ L ++ A D+D N L ++ N N + KF ++ G+I + LD +E +Y L + TDS A + V+V +ENDN P + ++L V+ E+ + + +L+A+D D + + G + D S ++ L + LD ET ++ + +D G PP+ + I+ + V D ND P F I E +P+ + V + A D D VN +L Y I AHF+ID +G + T + DRE TG E TV R + P S+ + V++ D ND AP F L GS VG++ A D D EA N + YA+ + + F + I T LDRE+ + + ++EA + P T R ++ N P++ D IN+ + +T+
Sbjct: 781 RATDKDSGKNGEVKYEIGEGNGGEKFGIFPDGQLYVRYELDRE-----TREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASL--RVFDREALIR------QGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAI-NEGN--EGGKFTVDASTGQITLLGSLDR-EETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFT--------ESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRST---GSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGL-FEVTV---RATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLRAAAGS----VVGTLQASDPD-EAENAAVRYAVT-------GGDAAILFRLDRRTGIIETSTELDRESGHGAFTLEVVAVEAKAAAPRTQRAENTIIANSMTFNHPLPRFPQ--DYESPINLLQGQTI 1417 HSP 5 Score: 138.658 bits (348), Expect = 3.354e-33 Identity = 156/584 (26.71%), Postives = 248/584 (42.47%), Query Frame = 3
Query: 867 PPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQD----ETAIASLSATDMDNX---------XXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPD---GRIFTTKESLDRETYDMHSFSIEAWDSG--PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEI-IRLVVKVSDSGPSPLTNTTIVRI 2549
PP++ + I++ D+NDN PVF P E+ ++EN + + + A D D N +T+S + F ++ +G + + LD +E +YLL ++ +D T + L V V++ NDN+P S H S + + E+ D I ++ A D D+ + + G L V L+V T+PLDRE+ + + D G T + + VLD ND P + E P + + +++A+D D GVN++L + I F++ N G L DRE+ Y L V DR P + LSS + +I+ D+ND AP F + PE S V +V A D D N + YA+ E + + G + +E LDRE ++ ++ A D G P+T ++ V V D NDN P++ I +E G V L A D D G N L Y+I G+ F+L+ G+L + + PL + L V+ D G ++T VR+
Sbjct: 1494 PPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSG----SEGAFVVDAASGVLRASRRLDR-EERASYLLTVRASDGTHATDARLSVAVRDANDNSPRFSR--HAYSFD---VAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNV--------TRPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVG-NDGQLSVARALDRERQSFYNLVVRVSDRAR----HPPAR-LSSAVRVSLILTDVNDNAPAFTSPRSALA-PEDSPVGAVVATVQAVDPD-SGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRE-LDREARQSYALTVLAVDKGRPPLTSTATLAVTVG--DANDNAPRFPRRE---YEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVAR-PLDRERTASYELAVRARDGGGPARSDTASVRV 2042 HSP 6 Score: 136.732 bits (343), Expect = 1.386e-32 Identity = 167/665 (25.11%), Postives = 269/665 (40.45%), Query Frame = 3
Query: 267 LQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMK--ENNFV-SLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLP-----LAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQ------NENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTD-------LSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH----AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGS-SPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWD 2183
++ +V+E++ G +I L D D + + + ++ E FV +G L +DRE + L + + + + +++ D ND+SP +++ ++ E + + LA D DS P ++ Y L +S + P LN V +DRE L A D G L + L +N+ D NDN+P + E+ L ++ A D D N +L FS +S + E R + G +G++ V + LD +++ + Y L ++V+D + L V+ + NDNAP + S L E+ +A++ A D D+ + + + L+ VT + L + LDRE + + T+ D G PP +T + + V D ND P FP I E P + V +L+A D D G N +L Y I F +D G L DRE+T Y+L D SD T +RV + D+NDC+P F+ Y E + P + + V+A D D+ + + Q++YA FSVSPDG + + SLDRE H I A D
Sbjct: 1521 MELEVEENTGEGEVIFTL----SATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASY--------LLTVRASDGTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVT-YALAPSEDSDWA--DGAFGLHPVTGALN-----VTRPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSI-SSGDPEGR---FAVGNDGQLSVARALDRERQ-SFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFT-------SPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTG-EVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSD--------TASVRVTLSDVNDCSPAFQLSPYTVHARENTQGPPVLILQVVARDDDLGS-SGQVTYAA-------AGGNDGGAFSVSPDGHVHLLR-SLDREAQPQHVLIITATD 2133 HSP 7 Score: 122.479 bits (306), Expect = 3.016e-28 Identity = 147/607 (24.22%), Postives = 244/607 (40.20%), Query Frame = 3
Query: 525 SNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFID-----QYLCQMFAKDLDISDNDKLTFSFGNSMNIE-DRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETI-LLVKVQNENDNAPVISILPHVNSSNNVLLVE--ENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDG-YPPQVTTKIINIQVL--DKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-------------DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHS 2270
S++ +++IS+ED+ND+ PV+ ++ + + E++ G + A D D N++ Y++ ++ S+ + + LR +DRE+ L + A D L++ + D NDNSP F + + E+ D + + A D D ++T++ S + + F ++ G + V + LD + Y+L + TD A T L V V + NDNAP + N+ L E E+ T++ +SATD D S S G R +V + + + LDRE F+ ++ D +PP + + + ++ D ND P F + + E PV + V + A D D G NS + Y + F+++ TG +R DRE Y L D+ L+ST + V + D ND AP F + YE +I E P V + A D D E N ++ Y + S F + P LDRE + ++ A D G + V V + D+ND P + S
Sbjct: 1497 SSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQG-QNALVTYSV--LSGSEGAFVVDAASGV----------LRASRRLDREERASYLLTVRASDGTH---ATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRA-CYVLRARATDGGGLAATARLYVNVLDANDNAPSVQ--------NDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGR----FAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAF-TSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDK--------GRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPD-EGANGELRY-------DIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLS 2057 HSP 8 Score: 91.6633 bits (226), Expect = 8.436e-19 Identity = 99/380 (26.05%), Postives = 156/380 (41.05%), Query Frame = 3
Query: 1464 PLDRETNEFFQATIKC------------QDDGY-----PPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI---DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSI-----PEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPI--THRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSP 2522
PLD F T +C +D+G PP + + I V D ND P F + ++E + L+A+D D G N+ + Y + F +D +GVLR + DRE+ Y L D + D+ + V ++D ND +P F + Y F + P+G + R +G+VLA D+D +++YA+ P E S + F + P LDRE+ + A D G + T R+ V+V+ D NDN P + S L+ + + G + + A D D G+N+ L + I G+ F + G L + + LVV+VSD P
Sbjct: 1456 PLDAPWRVSFDLTARCMFIVFSSLLSSLRDNGAGSFIRPPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASYLLTVRASDGTHATDAR-----------LSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFG-EVTYALA--PSE-DSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGLAATARLYVNVL----DANDNAPSVQNDS---LAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGND-GQLSVARALDRERQSFYNLVVRVSDRARHP 1812 HSP 9 Score: 80.4925 bits (197), Expect = 1.995e-15 Identity = 100/384 (26.04%), Postives = 163/384 (42.45%), Query Frame = 3
Query: 1434 VTKYTIL---LTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF--PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSI--DENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFY-----EFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVV---KVSDSGPSPLTNTT 2537
VTK L T PLDRE N + ++ +D G P + +N+ V D ND P F PA +V A D VG + + ++ D TG++ T D E +Y L +L +D LS + + D+ND P + ++ S+ E ++P V D+D N ++S ++V + H L+ P R+ LDRE M++ +I A D+G P+ + +VV + D+ND+ P+++ S+ + ++ G V + A+D+DSGLN+ L Y I+ GN+ F +++ +G L+ D E+ VV D G P T T
Sbjct: 80 VTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASV----------------AEDSPVGAALRDLLHRGRGPLAVPFDPKTGMVSTRQPLDFEARRQYTL--------SLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGG--NERGHF-VLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSA---YAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDESTG---LVTTDGKVDREVASSVVLNISAQDQGAQPKTAYT 430
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006996.1 (pep scaffold:Pmarinus_7.0:GL476780:2096:143714:1 gene:ENSPMAG00000006222.1 transcript:ENSPMAT00000006996.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 153.295 bits (386), Expect = 1.072e-37 Identity = 189/679 (27.84%), Postives = 305/679 (44.92%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDIS-DNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST-----KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRE-TNEFFQATIKC-----QDDGYPPQVTTKIINIQVL--DKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA----HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHR----VSVDVVVKIEDLNDNFPQWSHSS-DLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRL 2489
Q ++I++ D+ND++PV+ + V E+ + A D DS P+N I+ L ++ FSI + L + L + ++ I L ++A D GSPPL + + + D NDNSP+F + I+I EN + + A D D S + +L+ + ++E ++F IN ++G I +LD + V+ Y+L ++ D K + + + + NDN P LP+ + + EN T I ++SA D D + + R+ S + T L LDRE N A+++ D G PP+ T + VL D ND P F + + EG+P S + ++ A+D D G N + Y + A F +D TG++ T DRE Y+L LV +D LSSTT + +++ D+ND AP F S+ E + V S+ D+D +N ++S+ + + + FSV + T SLDRET +S IEA D+GP R ++DV+V D+NDN P + S ++ + N+TR G ++ ++A D D G+N + Y II GN+ F +N SG + PL D E + L
Sbjct: 111 QETAGRVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILP--TSAYSSYFSITVSGGYGVVTLARAL-----DYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIY----SLEGSTQFRINARSGDITSTTLLDR-EAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYA------VTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPNPFYRI-NAASGKIRTTGL---QLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLR--------LVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDAD-SGLNAELSFFITGGNQDGQ-------FSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVL--DVNDNRPLFLEGSYEVSVPENVTR----GAIILQVQATDIDEGINGRVWYRIISGNQDGNFLVNVSSGLISRGATPL--DRETVAL 743 HSP 2 Score: 141.739 bits (356), Expect = 4.429e-34 Identity = 151/568 (26.58%), Postives = 250/568 (44.01%), Query Frame = 3
Query: 546 ISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFS----IVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFY-INGKNGKIFVKQILDYDQEVN----TYLLPIQVTDSTKF-------AETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKL--EATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWD 2183
+ + D ND+SP++ ++ I IPE+ G+ A D D SP+ ++Q ++ + I +L D+ ++Q +L V A +D G+ TG + I + D+NDN P + ++I EN + + A D D+++N L ++ I+ + FY IN +GKI + +++N + I V+ + + A + V +Q+ NDN P LP+ L V E + + + ++ATD D + S + L R L T L + LDRE +Q + D G P +T +++ VLD ND P F A + V + E V +S V LN +D D G+N++L + I FS+ G++RT DRE Y L EA +D+ P + TT + V++ D+ND P+F + YE S+PE + + V A D D E IN ++ Y ++ + + +VS G I LDRET +H+ +EA++
Sbjct: 229 VEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGSTQFRINARSGDITSTTLLDREAVSQYILIVRA-VD-------------GGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYA------IDPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYA------LQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALP--RPDFQLDAATGLITTLVQ-LDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEA--------IDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPENVTRGAIILQVQATDID-EGINGRVWYRII-----SGNQDGNFLVNVS-SGLISRGATPLDRETVALHALQVEAFN 752 HSP 3 Score: 127.487 bits (319), Expect = 9.422e-30 Identity = 162/604 (26.82%), Postives = 263/604 (43.54%), Query Frame = 3
Query: 870 PLTGSTHLTINITDINDNSPVFLKPLTEISIKEN-NFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK------FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGG-----LKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA---------HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYV-----GSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPD-GRI-FTTKESLDRETY--DMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXX--XXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSND--PEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSK 2573
P +T + I ITD NDN+P F E+ + E + + + A D D DN ++ ++ GN+ + F I+ G + + LD++ YLL + TD + + + V V + ND P + S + V E Q IA+ A+D D+ S G +S DL V +Y LDRET F+ TI +D G PP +T + ++VLD +D P F + E V + V+++ ASD + G N + + H+ F D TG++ N DRE+ EY+L TV D + D + I+ V I D ND +PVF ++ YE IPE +SP V G + A D+D +N ++Y+++ S YF + D G + + LDRE +I D G +V + V + D+NDN P ++ +S + VG V V+KA+D D G+ ++ Y I G ++ F +++ +G L + P+ + PE + +VV +D P T + +R+ +E+ +
Sbjct: 1151 PAQATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNTA-----ATFGIDNGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWF-----LRSYEGPIDVSEG-QPGPRIATFMASDQDSGLNGELEYSIIDGDPRNEFVISPADGDLRV-RRYV-----ELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAAL--LQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRD-----NPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPE-NSPNGTVLTVLNGPIYASDADF-GVNATLAYSLLGG--------SSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGG--RRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLE--NSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGG-NDTFGIDESTG-LIVTVAPIDYETRPEYLLMVVA-TDQAPPFHTASCELRVSLQNELDE 1713 HSP 4 Score: 119.783 bits (299), Expect = 2.280e-27 Identity = 176/692 (25.43%), Postives = 311/692 (44.94%), Query Frame = 3
Query: 537 EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQL--LLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQ-EVNTYLLPIQVTD--STKFAETI-LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYT-------ILLTKPLDRETNEFFQATIKCQD--DGYPPQVTTKIINIQVLDKNDCTPHF---PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID--HAHFSIDENTGVLRTNSI-FDREKTGEYKLEATVYDRRNLVDS-----DPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGR--LVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEI---IRLVVKVSDSGPS 2519
+ I++ + ND+ P+++ +++ E++ +G+ LA DLD+ +S + ++ DK L+ L+ V A +D E + + ++A D G G + IN+ D+NDN+PVF + + +EN+ + ++ A D D N+++T+S + ++G G + + + LDY++ T L I D S T+ +V+V +ENDN+P+ + ++ + + ENI + ++ATD D + G L L + L T++ I T LDRE + ++ D DG + +NI +LD ND P + P A+T V E P + + ++A+D D+ N LVY ID + + I+ +G +RT + DRE + R++V S P + +S T+ V+++D+ND P F L Y + EG + V A D D E N ++Y+M + + + F + + TT LDRE + + A D G + + + + D+NDN P + H + +S+ E+V R +V L D+DSGLN+ L++ I GN+ F + + G L++ +S D E LV++ D+GP+
Sbjct: 15 RVHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFGQVSYH----------------FSDDSDKFSLDPASGLISVAAALDFEATPRFTVTVMARDGGGQETAG--RVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIF------DRNSYSIAIPENILAGATVLYVNATDGDQ-------SPEYGQLSL---IYSLEGSTQFRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIV---ENTPGGTDIFTVSAADPDLNENGTLVYAIDPPNPFYRINAASGKIRTTGLQLDREDLNPISFASM----RSIVVSGADRGSPPRRATASATVT-VLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPD-EGANGNVTYSMT-------AALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTF-HPARSAVSL----MESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDG---LVRTVVSLDRETKASYSLVIEAIDNGPA 648 HSP 5 Score: 115.931 bits (289), Expect = 3.092e-26 Identity = 159/637 (24.96%), Postives = 263/637 (41.29%), Query Frame = 3
Query: 540 IQISIEDINDHSPVW-TQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSIS-------------RYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLT-EISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT-YLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF--PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA---------HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKV-LSSTTIIRVIIKDINDCAPVFKKL------FYEFSIPEGSSPRMYVGSVL-AEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEA-----WDSG--------PITHRVSVDVVVKIEDLNDNFPQWS-HSSDLGLSIN 2294
+ +++ D ND+SP + S ++ + E + G+ + A D D+ + ++S +Y L N S + + + +KT +L R+ A D GSPP + + +L++ + D+NDN P+FL P +S+ E + ++A D D N ++TF + K I +G I V + D+E Y L + D I+ V V + ND P + L V + + V E++ + +A++ AT+ +G K + + S + T LL ++ E F T D G PP + ++VLD ND P F P T V I E +PV + ++ A D D G N + Y HA F I+ +G++ T DRE Y L L+ SD + V ST ++V++ DI+D PVF L + FSIPE S P VG+V A D+D+ A N + Y + K ++S+ + LDRE ++ ++A W P R +V V +ED+ND +P ++ H G++++
Sbjct: 1825 VYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTS-QFILFRIVA----------------LDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGG----DKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERP--AFLAPVQT----VSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRLL------KSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAVYSLI--------LLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGA-NAIVYYFIAAGNEGNKFNLSRW--------GLLVVLSDLDREVSPYYAIIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPVFTNHEYTAGVAVD 2411 HSP 6 Score: 112.464 bits (280), Expect = 3.334e-25 Identity = 162/636 (25.47%), Postives = 269/636 (42.30%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQS-KIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYL-----NQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS------TKFAETILLVKVQNENDNAPVISILPH-----VNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRET--NEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVP-VESFVTKLNASDCDVGVNSQLVYRIDHAH-----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISK----LYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGP------ITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKA 2342
+ + + D+ND +P + +S + I++ E + G R +A D DS N +L+ +SI+ + P ++ L +R +DRE L ++A+D G+PPL + + + + D++DN PVFL S+ E + + ++ A D + N + FY + + G ++V + LD ++ V Y L + V D+ + I++V + +ENDN+PV S + + NS N +L N + A+D D S GG + L D ++ L + LDRE + TI QD G + T + + VLD ND TP F T ++ E P V + V + A D D+GV R A F IDE+TG++ T + D E EY L +V +D +++ +RV +++ D F Y+ ++ E + P V V A +V K +E K H + + G I TT+ +LDRE D + ++ + D GP +T++ V V + D NDN P++ S + + G L+TVL A
Sbjct: 1268 VSVHVADVNDVTPWFLRSYEGPIDVSE-GQPGPRIATFMASDQDSGL-------------NGELE-YSII-DGDPRNEFVISPADGDLRVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRER-VAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLN-------GPIYASDADFGVNATLAYSLLGG-SSAYFLIDRD-RGNVSMALGQGLDREGIPGGRLELTILVQDGGR--RNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLM--------VVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEI-TTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGS--ATLVEVRESAAPGTLLTVLHA 1864 HSP 7 Score: 109.768 bits (273), Expect = 2.476e-24 Identity = 123/478 (25.73%), Postives = 205/478 (42.89%), Query Frame = 3
Query: 879 GSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQ--NENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTIL-LTKPLDRET--NEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVG---VNSQLVYRIDHA-HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYD------MHSFSIEAWDSG--PITHRVSVDVVVKIEDLNDNFPQW 2261
GS + I + + NDN P+F PL +S+ EN + + Q+ A DLD ++++ F +D KF ++ +G I V LD+ + + + + D ET V++ + NDN PV +V ++ EN T + + ATD D+ S S + ++V Y ++ L + LD E TI D G PP +T ++V D+ND +P F ++ I E + + V +NA+D D L+Y ++ + F I+ +G + + ++ DRE +Y L D + D + + + + D+ND P ++ L Y +I E + + +V A D D+ N + YA I P + Y + G+I TT LDRE + M S + D G P S V V ++D+NDN P +
Sbjct: 12 GSARVHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFGQVSYHFS-----DDSDKFSLDPASGLISVAAALDF-EATPRFTVTVMARDGGG-QETAGRVRINLLDVNDNTPVFQRDSYVGTA------RENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFS-ITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGSTQFRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQK------TGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNE-NGTLVYA--IDPP------NPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSF 460 HSP 8 Score: 95.5153 bits (236), Expect = 5.747e-20 Identity = 110/442 (24.89%), Postives = 196/442 (44.34%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLL-RVDANIDRXXXXXXXXXXXXXDSGSPP--LTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQE-VNTYLLPIQVTDSTKFA---ETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT-KPLDRETNEFFQATIKCQDDGYPP--QVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVL-RTNSIFDREKTGEYKLEATVYD 1820
+ I++ D+ND+ P W + I E++ G+ + A D D + + TL Y + + I N+ K L L R D N +++ D GSPP T S +T+ + D+NDN P F+ + + E + L Q+ A D D N +T+S ++ R F ++ G + ++ D+E V Y L + TD A T L + V + NDNAP + + + + + E++ ++ + SL+ TD D+ +GG + + SV + ++ T LDRET + I+ D+G + T +++ VLD ND P F V + E V + + ++ A+D D G+N ++ YRI +F ++ ++G++ R + DRE + L+ ++
Sbjct: 334 VNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENG-----TLVYAIDPPNPFYRI--NAASGKIRTTGLQLDREDLN-PISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAAL---PRPDFQLDAATG--LITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTF------HPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQ----FSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGNFLVNVSSGLISRGATPLDRETVALHALQVEAFN 752 HSP 9 Score: 90.5077 bits (223), Expect = 1.645e-18 Identity = 127/563 (22.56%), Postives = 235/563 (41.74%), Query Frame = 3
Query: 438 DIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVW-TQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRV--DANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXX--XXGGLKLSRVLTDLSV-VTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQV-TTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTK------------LNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDS-------DPT-EKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQIS 2033
D+ + K +Q + + +S F + + + D+ND+ P++ + +++ E G+ A D D+ P+ ++ + ++ +L + + ++RV ANIDRE L+++A D G+PPL+GS + + + D+ND P FL P+ +S+ E+ + ++ + A + N K T+ ++ F ++ +G + ++L + N + + + L V+V + ND+ PV + P+ V+ + E + I + A D D S +GG+ SR + T I + LDRE+ + + D G P +T+ + + + D +D P F V D G P +SF A D DVG N+ + Y I + F++ G+L S DRE + Y + N + DP+ ++ L +RV ++DIND PVF +E++ G + VGS L + +EA++R +
Sbjct: 1905 DVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVT-FRIESGGGDKLSIGP------------SDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGI----GKNAFTVHATSGLVTSTRLLKSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPN----GTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVG-SRDWESFRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVF-----IVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGNEGNKFNLSR-WGLLVVLSDLDREVSPYYAIIVKASSNPNWTPAVTTGPEFDPSKDRTLRE---VRVYLEDINDQWPVFTN--HEYT--AGVAVDAKVGSELLQ---LEAVDRDVG 2429 HSP 10 Score: 88.1965 bits (217), Expect = 1.011e-17 Identity = 141/547 (25.78%), Postives = 236/547 (43.14%), Query Frame = 3
Query: 882 STHLTINITDINDNSPVF-LKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGN--SMNIEDRSKFYINGKNGKIFVKQI-LDYDQEVNTYLL-PIQVTD------STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNX--XXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKP---LDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI---DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNL--VDSDPTEKVLSSTTIIRVIIKDINDCAPVF--KKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMV----IKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGL---SINITREETVGRLV-TVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQ 2426
++ +N+TD NDNSP F T + ++E+ L + A D D N ++ I + I ++G V D+ ++ + ++L I D ST F +++++ V NDN P+ ++ + V E T +AS+ ATD D + S GG KLS +D I+ P +DRET + + D G PP + I+ + V D ND P F A + TV + E + V SFV + A++ G N++ Y+I F++ +G++ + + Y+R NL V +D L + V + D+ND PVF +I E + + VLA D D E N + Y+ + + + +S F ++ I +T +LDRE+ ++S + A D G P+++ + + V ++D++DN P + D G S +I G V V A+D+D G N+ + Y I GNE F L++
Sbjct: 1822 GAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDV---NDNVPIF-----LSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDKLSIGPSD-------GIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRLLKS------------YERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGD-EGQNGAVRYSFLHAGGVGSRDWES------FRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGNEGNKFNLSR 2334 HSP 11 Score: 82.0333 bits (201), Expect = 7.890e-16 Identity = 179/751 (23.83%), Postives = 295/751 (39.28%), Query Frame = 3
Query: 417 GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFE-----IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENN---FIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVL----------------TDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIIN-------IQVLDKNDCTPHFPAAITT-VYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFS----------IDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVF-KKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSP-DGRI-FTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPL 2525
G ++V +DRER+ + L + V + +Y + ++I D ND+SPV++Q IPE+S G+ + S D ++ TL Y S L S + L D+ N + + + +DRE I L L + L + + D+NDN+P F + EN+ + + +DL + D + +S + N F I+ G I +DY+ YLL + TD A L V +QNE D S+ + + + E T + ++A M + L L+ ++ +L + I LDRE + + T+ +D G P + + N + V D+ND +P F A T V + E + +T L+A+D D G N + R H H I +GV +I D K ++ + + + +V D S+T + VI+ D+ND P+F Y S+ E +P V SV A D+D N Q+++ + KL S+ P DG I ++DRET ++ + A D G S V V ++D+ND P + ++++ +VG V +KA ++ G N+ Y+ I G F ++ SG + L E L +D G PL
Sbjct: 1447 GLVYVNRPLDRERVAEYR-------LTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVN-ATLAY---SLLGGSSAYF--LIDRDRGN-VSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGN----DTFGIDESTGLIVTVAPIDYETRPE-YLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAA------LSEAAVPGTVVVRVAAPQMKAPPKLP--------LPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDREATDSYMLTVLSRDGG-PREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARA-HTHTGTRIPPQYILIIQNESGV----TIVDVAK-ADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDAD-AGPNGQVTFRI------ESGGGDKL--SIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQ---TVSVLESLSVGSFVATVKATENYKGHNTKYTYK-IAGIGKNAFTVHATSG--LVTSTRLLKSYERFNLTAVATDHGRPPL 2142 HSP 12 Score: 77.411 bits (189), Expect = 1.634e-14 Identity = 92/366 (25.14%), Postives = 154/366 (42.08%), Query Frame = 3
Query: 855 DSGSPPLTGSTHLTINITDINDNSPVFLKP--LTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK----FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLS-ATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT-KPLDRETNEFFQATIKCQDD-GYPPQVTT------------KIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYR------IDHAHFS---------------IDENTGVLRTNSIFDREKTGEYKLEATVYD 1820
D G PPL G L + + D+ND+ PVF+ P T ++I E + + ++ A D D N + +SF + D F IN +G I + LD + + Y L + +D + + L V + + +DN PV +LP + + E+ TA+ ++S A D D + I + G + ++ ++++ +L+ LDRE + ++ +K + + P VTT + + + + D ND P F T + V S + +L A D DVG NS ++YR I H+ S E G+LRT +F G + LE D
Sbjct: 2136 DHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQA-VYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGNEGNKF-----NLSRWGLLVVLSDLDREVSPYYAIIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPVFTNHEYTAGVAVDAKVGSELLQLEAVDRDVGNNSIVLYRILSILYIKHSSNSSTRMYNIFTLGRCARAGERDGILRTYDLFTAYGPGYFMLEVVAAD 2495 HSP 13 Score: 69.707 bits (169), Expect = 4.546e-12 Identity = 100/383 (26.11%), Postives = 160/383 (41.78%), Query Frame = 3
Query: 1170 IQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT--KPLDRETNE-FFQATIKCQDDGYPPQ---VTTKIINIQVLDKNDCTPHFPAAITT-VYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA----HFSIDENTGVLRTNSI--FDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETK-SHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDS--GPITHRVSVDV-VVKIEDLNDNFPQWSH 2267
I +T + A T +L+++ +ENDNAP ++ VLL E A+A+++A+D D + G + D T +LT K LD E + + + D P +T +++ V D ND TP F + + + EG P T + ASD D G+N +L Y I F I G LR DRE Y L ++ D L+ST + V + D++D PVF L S+ E ++ V V A D+ N + A +++ T + + +++ S G ++ + LDRE + ++ D+ P R D+ +V I D NDN P +S
Sbjct: 1145 ICLTATPAQATTSVLIRITDENDNAPAFGA-----ATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNTAATFGID-----NGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPRIATFM-ASDQDSGLNGELEYSIIDGDPRNEFVISPADGDLRVRRYVELDRETQAFYNL--------TIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDA-----NEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRP-LDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQ 1502
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 184.882 bits (468), Expect = 3.324e-47 Identity = 195/695 (28.06%), Postives = 318/695 (45.76%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETI---LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVY---RIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLV---VKVSDSGPSPLTNTTIVRIYFHSEVSKLP 2579
+S +++I+I ++ND+ P + V +IPE I + A D D +P T V + F I +S L+ V +DRE L++ A ++GS + + TI + D+NDN+PVF S+ EN I Q + ++ A D D +N K+T+ +++ D SKF +N G + K+ LD + + +Y L + D K +++ + + + + NDN+P S S L V EN + + I + A+D D + S G + D T I + +DRE + TI +D G PP V+T + I V D+ND +P F + T+ IDEGV + S V + A+D D G N+Q+ Y R D + F+I+ GVL +RE Y L DR + +++S + V++ D+ND PVF Y S+ E S+ V +V A+DSD+ A N + Y+++ E + I+ S G I TT LD E + + A DS + +V +++ +LND P ++ + + E +V+K SD SL+Y I+ G + + F ++Q+SG ++ D E++ L V+V+D+G PL+N T V I E P
Sbjct: 977 KSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTP------LTFDIVEGNAGSSFKIDQSSG---------LISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYE----LSVGDTSKFEVNPATGLVTTKRPLDREDQA-SYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFS------QSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRID---STTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGS--------PMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGA-NAVLRYSIISGNDEKRFKIN------STSGVIMTTTP-LDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQ-----NYTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRSG---IISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSP 1615 HSP 2 Score: 176.792 bits (447), Expect = 1.165e-44 Identity = 211/799 (26.41%), Postives = 346/799 (43.30%), Query Frame = 3
Query: 273 FQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSL--VNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLK-----IQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETI---LLVKVQNENDNAPVIS-------ILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTK-PLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF--PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLM----KQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLP 2579
F+V E S G IG + D D S ++ + + + S+ G + +K +D E KK Q +++ K +S+ +++ ++D+ND+ P + +S + E+ G A D DS + IS L N + + ++ RV +DRE I L + A+D +T + I+I D NDN P F P + +I E++ + Q+ A D DI N +T++ GN N F ++ ++G + V+ LD + + +Y L ++ +D+ ++I + V V + NDNAP I + + VL V+ +DE + +++ L LS +D + +L+K PLD ET +Q T+ +D G P + T + I +++ ND P F PA +T+ I E V + + V KLNA+D D + L + I + F ID+++G++ DRE T Y L R E V ++ T IRV+ D+ND APVF Y S+ E V V A D D E N +++Y + + SK F V+P + TTK LDRE +S + A D G + + + I DLNDN PQ+S S ++ +T G + + A D D+G N + Y II GN F+++ +G + ++ ++ L++ L + DSG P +T V I E P
Sbjct: 589 FRVSESSSPGHQIGQVAAT----DADDSSNGDVRYALSDNTDVFSINTSTGLITLKTQLDYE----KKTQ------YMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAM----------DRFTGEITTRVP--LDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGP-SRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGN-----SFQLDPRSGILSVRSTLDR-ETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAIT-------------------LSLSGEGSDNFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTS--IPEDVAINTHVVKLNATDSD---GTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVV-----RATETGSQGESVYNNAT-IRVL--DVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRD-EGENAKVTYELSV------GDTSK--FEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSK---YTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALAS----YNLTISAKDSGVPPWVSTAFVAITVADENDNSP 1306 HSP 3 Score: 175.637 bits (444), Expect = 2.372e-44 Identity = 211/781 (27.02%), Postives = 341/781 (43.66%), Query Frame = 3
Query: 303 LLIGDLVENYRIQDFDLSRRENLNFQMMKENN--FVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH--FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEII---RLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRFFEKDL 2609
+ +G +V D D+ L++ ++ + F G + K DRE TK + L +S ++I I D+ND+ PV++ ++ ++ E IG+ A D D+ +N+ RY+ N + V ++ V ++D E+ L L D GSPPLT ++HL IN+ DINDN PVF + +KEN Q+ A D D S N L F GN D F I+G G I + + DY+ + Y L +Q D K+ + + +++ ND++PV S SN + E+ + + +++ATD+D+ G D +I ++ LDRET + ++ +D G + ++ + I + D ND +P F + P + ++ A+D D N + Y + FSI+ +TG++ + D EK +Y + T D P+ SS T+++V++ D+ND P F K Y ++ E + + V V A D+D A N +ISY+++ S + F++ TT+ LDRET +S +I A D + + V + I D NDN P ++ S NI+ + G V L A D D G N ++ Y II GN+ F+L+ +SG L + + D E I LVVK SD+G SP + T H V + + FEK L
Sbjct: 181 VAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQGVIRTKGAFDRE---TKASYQVALR--AQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNG-NNADLRYSFTSGNTNHAFTLDAVTG-----------VVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENT---PAGTQVSATDRDSSTNGALVFGIIKGN-----DDGVFTIDGSTGIISIAKSPDYENKTR-YDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFS------PSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNID---ANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQ-IGQVAATDADDSSNGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKD-----GGTPSR---SSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGA-NGKISYSIL-------SGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRF----NISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRSGILSVRS---TLDRETIPSYTLVVKASDAG-SPQQSIT---ASIHVSVLDVNDNAPRFEKSL 898 HSP 4 Score: 173.711 bits (439), Expect = 8.948e-44 Identity = 204/747 (27.31%), Postives = 328/747 (43.91%), Query Frame = 3
Query: 303 LLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVN---GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDV--GVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLG-LSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEII-RLVVKVSDSG 2513
L IG V D D + +++ + VN G + K +DRE L + + + QS I ++I D+ND+SP ++QSK + + E++ GS LA D D+ + R T ++ + F I D T ++ V +DRE + L + A+DSG PP + + I + D NDNSP+F T I E I + + A D D N ++ +S D S F IN NG + VK+ ++ + V TY L I+ +D ++ L V V + NDN PV NS + + V EN T++ +++A D D + + S G R + T I+ T PLD E + + D Y + + I+V++ ND TP F T + E P + V K++ASD D ++ +V D FSID+ +G++ T + DRE Y ++ V D N LS+ T + + I D ND +P F Y SI E S+P + + A D+D E N +I+Y + F + + T + LDRE + +I+A D G S+ + V + D+ND+ P + SS G + N +E V R++ A D+D+GLN+ L + ++ +F L+ +G + K PL + + + L + V+D G
Sbjct: 1112 LPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNPATGLVTTKRPLDRE-----DQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANG---RVTYSIISGNHGNAFRI------DSTTGRITVVGV---VDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRG----DTSAFAINAMNGVLTVKKEINR-ETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVF------NSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKIN---STSGVIMTTTPLDFEEKSQYGLEVTATDSKYTAKTN---VTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGN--------PPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDAD-EGTNARITYNLSRNDA----------FMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRIL----ASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDIS-TKVPLDREQQAVYTLRIGVADKG 1800 HSP 5 Score: 172.17 bits (435), Expect = 2.677e-43 Identity = 202/699 (28.90%), Postives = 313/699 (44.78%), Query Frame = 3
Query: 546 ISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD--STKFAETI-LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVV-VKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEII---RLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLP---AESRF 2594
I+++D+ND++P + S + E +GS A DLD + +S +S+V T +Q ++R DRE ++ L A+D GSP +G + I I D+NDN PVF S+ E+ I + + A D D +N L +SF GN+ + F ++ G + V + LD++Q ++Y L + VTD S +T LL+ V + NDN PV S P S V+EN T + SATD D+S+ G D S I + K D E + T++ +D G P + T + I + D ND +P F + + I E + S V + A+D D G +L YR+ + F+ID N+G +R +S DRE T Y L+ D SS+T + + ++DIND +P+F+ Y F + E SSP +G V A D+D ++ N + YA+ + FS++ + T K LD E + ++ A D G R S+ VV V ++D+NDN PQ++ S + + G V + A D+DSG N ++Y I+ GNE+ F +++ +G + + PL D E I L + D T V I E P SRF
Sbjct: 156 ITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLS--------------YSLVSGDTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNH-----AFTLDAVTGVVTVSRSLDFEQR-SSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFS--PSAYQSR----VKENTPAGTQV---SATDRDSSTNGALVFGIIKGNDDGVFTIDGST---GIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDG--------GSTSRSSSTRVTIALQDINDNSPIFQGP-YVFRVSESSSPGHQIGQVAATDAD-DSSNGDVRYAL---------SDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGG-TPSRSSLTVVKVMVDDVNDNPPQFAKSL---YTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEI-TTRVPL--DRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRF 796 HSP 6 Score: 169.474 bits (428), Expect = 2.122e-42 Identity = 175/655 (26.72%), Postives = 292/655 (44.58%), Query Frame = 3
Query: 417 GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQ----------SNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQL--LLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKP-LDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID-HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLK 2339
G++ V +DRE + + YNL I S F + I++ D ND+SP++ ++ I E IGSR + A D D +N+Q+ +SIV +N + +L V I+RE + L + A D GSP +T LT+ + D+NDN PVF S++EN+ + + A D D+ N L +S ++ D +F IN +G I LD+ +E + Y L + TDS A+T + ++V N ND I P N V EN T++ +SA+D D+ ++ GG + S+ + I+ T LDRE + ++ D G PP + I++LD+ND +P F ++ + I E SF KL A+D D G N+++ Y + + F I ++GV+ DRE Y L D P + +S+ IRV + DIND P+ S+ E +V +LA D+D +N +++++++ S+ K F++ +TK LDRE +++ I D G + DV++ + D +DN P++ + N+T E++ R ++++
Sbjct: 1258 GRITVVGVVDREALAS--------------YNLTISAKDSGVPPWVSTAF-VAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEG-------------SNAQV-FYSIVRGDTS-AFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSI---ISGNDEKRFKINSTSGVIMTTTPLDF-EEKSQYGLEVTATDSKYTAKTNVTIRVINLND------ITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGSLSYSIV--GGKDSDK----FSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDH-----GTPPQ---ASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADT-GLNAELTFSLL-------SNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPT-----EYNVTISESLPRGASIVQ 1845 HSP 7 Score: 139.813 bits (351), Expect = 2.529e-33 Identity = 153/536 (28.54%), Postives = 243/536 (45.34%), Query Frame = 3
Query: 879 GSTHLTINITDINDNSPVFLKPLTE--ISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLS--VVTKYTILLTK-PLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQ 2456
G T + I++ D NDN+P F PL +I+EN Q + + A D D N +T+S + N KF +N K G+I LD++ + ++Y + I D K + L+ V + NDNAP ++ + V E++ + + L+A D+D + L S V D S V ++ TK DRET +Q ++ QD G P + + I++LD ND P F +A T +DE V + + + + ASD D G N+ L Y +HA F++D TGV+ + D E+ Y L +V DR S P L+ T+ + + + DIND PVF Y+ + E + V A D D + N + + +IK + F++ I + +S D E + +++A D G + V + IED+ND+ P +S S+ S I +G V + A D DSG L Y +I GN F ++ SGS+ + +
Sbjct: 52 GRTVVVIDVKDENDNAPEF--PLNSYVFNIRENTPAAQ-VAIVTATDRDSGTNAAITYSLFSGEN-----KFMMNSKTGEIRTVTPLDHETK-DSYTMRISAFDG-KHTTFVPLITVDDVNDNAPFFALSVYKTG------VYEDVAVGSIVRQLTAVDLD--------VGINARLSYSLVSGDTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHA-FTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDR----GSPP----LTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQVS---ATDRD-SSTNGALVFG-IIKGNDDG------VFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSN---YSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSE 540 HSP 8 Score: 128.257 bits (321), Expect = 8.908e-30 Identity = 149/576 (25.87%), Postives = 260/576 (45.14%), Query Frame = 3
Query: 300 GLLIGDLVENYRIQDFDLSRRENLNFQMMKENN---FVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQ-LKLFS---IVYNSLP-DKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGN-SMNI---EDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI---DHAH-FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPR 1970
G+ IG V D D + + +++ + ++ +NG L VK +I+RE + T L + + ++ E+ + + D+ND+ PV+ + ++ E+S S L +A D N++ RY++ N+ + K+ S ++ + P D +Q L V A + T T++TI + ++ND +P F + S++EN+ + ++ A D D SFG+ S +I +D KF I+ ++G I +LD + V+ Y + ++VTD+ T + +K+ +ENDN+P +SS+ + EN + L+ATD D + LSR + + I L +PLDRE + I+ +D G PPQ ++ I + V+D ND P ++ + E P E+ V ++ ASD D G+N++L + + +H F++D TG + T DRE+ Y L V D+ N P+ LSS + + + D +D P F+ Y +I E S PR
Sbjct: 1320 GVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPT-----YTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSA-QSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSK-------------------YTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRD---------SFGSLSYSIVGGKDSDKFSIDQRSGIISTADVLDR-ELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSP------KFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARIT------YNLSRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGN-----PS---LSSVADVIIDVIDEDDNCPRFQPTEYNVTISE-SLPR 1839 HSP 9 Score: 103.99 bits (258), Expect = 2.255e-22 Identity = 95/362 (26.24%), Postives = 161/362 (44.48%), Query Frame = 3
Query: 1461 KPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI--DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVI-IKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTT 2537
+ DRE+ ++ T+ QD ++ I V D+ND P FP I E P V + A+D D G N+ + Y + F ++ TG +RT + D E Y + + +D ++ TT + +I + D+ND AP F Y+ + E + V + A D D+ IN ++SY++V YF+V G + TK + DRET + ++ A D G + V ++I D+NDN P +S + + ++ + +G + + A D D+G N+ L Y GN + F L+ +G + + + L + V+D G PLT+T+
Sbjct: 26 RKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQ-VAIVTATDRDSGTNAAITYSLFSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGKH-------------TTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDV-GINARLSYSLVSGDTS--------YFTVDSQG-VIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQ---YTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTS 360 HSP 10 Score: 90.1225 bits (222), Expect = 4.333e-18 Identity = 109/394 (27.66%), Postives = 168/394 (42.64%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQL--LLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILL--------TK-PLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCD 1679
+ I + ++ND +P +TQ ++ E+S + A D DS S+S +SIV DK ++Q ++ +DRE + + + D+G+PPL+ T +TI I D NDNSP F SI EN+ + ++ A D D N ++T+ N+ F I +G I + Q LD + + +TY L IQ D + + + V V + ND+ P+I NSS+ V EN ET + + A+D D GL + LS K L TK PLDRE + I D G P + + I V+D++D P F V I E +P + + ++ A D D
Sbjct: 1500 VTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSF--GSLS--------------YSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITY------NLSRNDAFMIGASSGVITLAQPLDRENK-STYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLI------NSSSLRGSVRENQPKETHVMRILASDADT------------GLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDID 1852 HSP 11 Score: 60.077 bits (144), Expect = 5.198e-9 Identity = 70/230 (30.43%), Postives = 107/230 (46.52%), Query Frame = 3
Query: 1713 DHAHFSIDENTG-VLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGN 2399
D F+ID +TG + T FDRE Y+L D N + T++ + +KD ND AP F Y F+I E ++P V V A D D N I+Y++ S +K + S G I T LD ET D ++ I A+D H V ++ ++D+NDN P ++ S + + VG +V L A+D D G+N+ L+Y ++ G+
Sbjct: 8 DQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAAN--------RCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRE-NTPAAQVAIVTATDRD-SGTNAAITYSLF-------SGENKFMMN-SKTGEIRTVTP-LDHETKDSYTMRISAFDG---KHTTFVPLIT-VDDVNDNAPFFALSV---YKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGD 211
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 178.718 bits (452), Expect = 2.385e-45 Identity = 204/732 (27.87%), Postives = 326/732 (44.54%), Query Frame = 3
Query: 417 GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNY-FEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDS---TKFAETILLVKVQNENDNAPVISIL---PHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLP 2579
G + A IDRE Q LN SN +Q+ ++DIND+ P + + I E + + + A D D+ +N YT+ +N+ FS+ + P + L + + +DRE + +L + A D G+P L G + I I D ND++PVF + SI EN + ++ A D D N + ++ + I+ S F ++ G I KQ LD++ + N+Y + +D +K + + V + NDN+P + I PH + + + EN T IA + TD D+++ + + G + + Y I L KPLDRE F+ T+ D G P + T + I V D ND +P F + T I E S+V +LNA+D D G N + Y I D F +D +G++ T DRE+ + T D S P + +T + V I D ND P F K Y+ +I EG+S V V A D D N +I+Y + + + ++ L F ++ + TK LDRET ++SF++ A D G SV V + I D+NDN P + +I E G+L+ V A D+D G N+ ++Y+II GN + F ++ +G + + E L++ D G T +V + ++ LP
Sbjct: 49 GVISTTARIDRETTTQISLQLRTLN----------PSNQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAG-NNGTVDYTIASGDNT--ATFSLGTTACPTGSTLCVITKKP---LDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAI-DWDAIQSNSIFDLDSSTGVIRTKQNLDFEVK-NSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPH---NGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNGDD--EGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDH----GSAPK----TGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVD-SGDNGRITYEI----SSSDAQVNGL-FELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFA---SIMENEPPGKLLQV-TATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLP 739 HSP 2 Score: 155.221 bits (391), Expect = 4.098e-38 Identity = 182/653 (27.87%), Postives = 281/653 (43.03%), Query Frame = 3
Query: 528 NYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSP----VFLKPLT-EISIK-ENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQE-VNTYLLPIQVTDSTKFAETIL---LVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH------FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSS-DLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSG 2435
Y I I+I D NDH+PV+TQ+ + +I E++K G A D DS + I +Y + + +I NS+ D + ++R N+D E ++A D G P +TIN+ D NDNSP +L P + +I+ EN+ I+ + + D D + N + N +D F + G F++ D+E V Y L + VTD + + L L+ V + NDN+P + S+ + E Q+ + + L+ATD D S +GG L D + KPLDRE TI QD G P+ + + + ++D ND P F + I EG + + V +++A+D D G N ++ Y I + F ++ TGVL T S DRE Y D DP L S+ + + I DIND APVF + Y SI E P + V A D+D E N ISY ++ + FS+ + +T SLD E + S I A D G + V V + + DN P + + + + N+ + VGR+ K N S++Y I+ G+ LF ++ G
Sbjct: 188 GYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDI-KYAIDW--------DAIQSNSIFDLDS-STGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNG---DDEGCFKVEFL-GFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFT------SNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQ---SGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDH-----GDPQ---LMSSVKVELTISDINDNAPVFYPVEYFASIMENEPPGKLL-QVTATDAD-EGTNAVISYDII-------GGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTK------DKNGSISYAIVSGDPTNLFLVDSTGG 794 HSP 3 Score: 146.747 bits (369), Expect = 1.731e-35 Identity = 199/777 (25.61%), Postives = 322/777 (41.44%), Query Frame = 3
Query: 306 LIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQC-CCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEV-----NTYLLPIQV--TDST-KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH----AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETY----DMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSH--SSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLP 2579
L+G +V N D D + + +Q+ + +N V I R T ++ + + Q + I I++ IN H P +T S V ++ + +++ +A D DS + + Y++ N + LF I K Y+ + LL+ +L++ A D G P + S +TI I D ND+ +F+ ++ EN+ + + A LD S + +S I S F ++ ++G+I + LD ++ + N Y++ + D+T K + I++V V + NDNAPV S + + V E + + + A D D S G + + + S + L+K LDRET + +K D +T I I V D ND P FP + TV I E + S V LNASD D+G N + Y I + A F ++ TG L D E T Y+L T D L+ LSST + V + D+ND AP+F ++ E + VG A D D N I+++M S FSV+ TT ++D ET D + A D G + V++ D NDN P + ++ G S+N V + A D D N + Y II GN + F L+ +G L ++ Q + ++P I +L ++ SD G T+V ++ + P
Sbjct: 858 LVGQVVYNAAAVDLDAGKNGLVRYQLTSNAEGLLWINSTSGV---IKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLS-IN-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQL-FYSIPQGN--EEGLFGIFPGG---KLYIRKSLLQA-------LKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSL-----ISSESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYA------ITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELH---LSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQD-HGLIP-------LSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDT-GTNAHIAFSMY-------SQTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAAAGSSLN----------VMTITAEDPDRNSNGKVTYSIISGN-NGYFNLHPSTGQLQMIHQ-IPDNPTIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGP 1574 HSP 4 Score: 131.339 bits (329), Expect = 9.901e-31 Identity = 180/683 (26.35%), Postives = 302/683 (44.22%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPL-AKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG--PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFH 2558
+ I + D+ND+SP +T + NI E ++ GS Y L L A D D DN Y++ N+ L F + + S L+ +DRE++ + + + A+D GS P TGST +T+ I D NDN P F+K + +I E I + Q+ A D+D DN ++T+ +S + + F +N + G ++ K LD + + + Y + D + + + + + NDNAPV + + S + EN + + ++ATD D + + GG D S T+ LD E EFF I +D G T ++N+ VL+K D P F + + E VP + V ++ A+ D N + Y I F +D G+++ N DRE+ +Y L V R V K LS+ + + + D ND AP F I +G+ VG V+ + A++ +++ Y+ S+ L + S G I ++ D + ++ + A DSG P +++ + + I ++ P+++ SS + ++ + + + A+D DSG N L Y I QGNE LF + G LY+ K L L+V+ +D G + + V IY
Sbjct: 411 VLIDVTDVNDNSPAFTSNAYTANISELAQNGS-YVLQLNATDPDEG-DNGTVSYSITGGND--LGWFQVDFQSG---------LVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSS-DAQVNGLFELNTQTGVLWTKSQLDRETK-SLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFAS------IMEN-EPPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTL---ASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKD--KNGSISYAIVSGDPTNLFLVDSTGGIIKINGDMDREEKAQYLL--AVIARVGTV------KPLSAQATVNIEVLDRNDNAPQFSTSSVIVDI-DGT---WLVGQVVY---NAAAVDLDAGKNGLVR-YQLTSNAEGLLWINSTSGVIKLARKLTDGDET-QYTVQVLASDSGSPPQHSTMTIHITLSI----NHPPKFTLSSYV---THVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGI-FPGGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQ 1041 HSP 5 Score: 124.405 bits (311), Expect = 1.236e-28 Identity = 169/682 (24.78%), Postives = 292/682 (42.82%), Query Frame = 3
Query: 264 SLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMK-ENNF-VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYN-LKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLL--LRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST--KFAETI-LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD---NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTI-LLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF---PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI---DHAHFSIDENTGVLRT-NSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAW---DSGPITHRVSVDVVVKIEDLN 2243
+ +F V E+S G L+G LV + D SR +++ + ++ E++F V + +G++ + +DRE + + +YN I+ + + +++ D+ND++PV++++ I + E S GS + A D D DN+ K+ +S+V + DK ++N L + +DRE L++ A D+ + L + + I + D ND PVF + ++I E+ I + + A D DI N + +S N N+ + F + G++ V + LD+ + Y L I D + T+ + V V + NDNAP+ P L V EN+ + +A+D D N+ S S + S + T I L T P R++ FQ + D G P T K I +QV D+ND +P F PAA ++ V + A D D N ++ Y I ++ +F++ +TG L+ + I D + ++A SD + + T++ V + P F Y+ S+ E V +VLA ++N I Y + S SK F V + T +DRE SF++ + GP S V + ++D+N
Sbjct: 1054 TFRFAVAENSSPGTLVGTLVAHA----LDHSRTKDIVYSLISSESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEG-DNA------KF-------FYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNG-NLA--AMFDVESATGRLIVAKSLDF-ETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPV------TLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLETMPAGRDS---FQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAAAGSSLN--------VMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQIPDNPTIYQLTIQA----------SDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQ-SSLNGNIEYYLT-------SDSSKGGFEVVKSTGVVKTTRGIDREGMGA-SFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 HSP 6 Score: 90.5077 bits (223), Expect = 3.108e-18 Identity = 159/655 (24.27%), Postives = 259/655 (39.54%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQ--NENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVV--TKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRM----YVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVS-----------PDGRIFTTKESLD--RETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSL 2441
+ ++I D ND+ P + +S I E + IG+ A D+DS DN Y + + LF + +L + +DRE +LA+D G P L S + + I+DINDN+PVF SI EN + L Q+ A D D N +++ + + F I+ G I LD++ E L+ K+A +V V N+ DN PV + N V EN+ T + + AT D + +I +S T+L +V T I + +DRE + + + P +NI+VLD+ND P F + V ID V V A D D G N + Y++ G+L NS +G KL R L D D T+ ++V+ D + P + ++ P+ YV VLA + ++ Q Y + + K+ +L++S+ P G+++ K L + +YD+ + A D G + SV V + I+D ND+ + +++ + + G LV L A D + Y +I H F ++ +SG +
Sbjct: 516 VTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSG-DNGRITYEISSSDAQVNGLFEL---------NTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEPPGK-LLQVTATDADEGTNAVISYDI---IGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVF-LYEMYN-----FTVYENVPKGTLVGRVYATTKDKNGSISYAI-------VSGDPTNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQL------TSNAEGLLWINS-----TSGVIKLA------RKLTDGDETQYT------VQVLASD-SGSPPQHSTMTIHITLSINHPPKFTLSSYVTHVLAS----QPLSYQFFYVVAVDQDSGKN--GQLFYSIPQGNEEGLFGIFPGGKLYIRKSLLQALKGSYDLI---VRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNT---FRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESH--FAVDVRSGQI 1105 HSP 7 Score: 55.8398 bits (133), Expect = 1.018e-7 Identity = 63/226 (27.88%), Postives = 96/226 (42.48%), Query Frame = 3
Query: 1611 TVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFT--TKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLG 2282
T ++ E P ++V K++ + G Q F + NTGV+ T + DRE T + L+ R L +P+ + +S ++V + DIND P F L+Y I E A D D N + Y I + + S L + P G TK+ LDRET D + +I A D G + + I D ND+ P ++ +S LG
Sbjct: 13 TFHVQEEQPPGTYVGKVDGASAFEGSPKQ---------FGFNSNTGVISTTARIDRETTTQISLQL-----RTL---NPSNQPIS----VQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPD-AGNNGTVDY--TIASGDNTATFS-LGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLG 213
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 179.104 bits (453), Expect = 2.562e-45 Identity = 207/732 (28.28%), Postives = 330/732 (45.08%), Query Frame = 3
Query: 417 GKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVW---TQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDA-NIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKF----AETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGG-----LKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA--------HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
G + K +DRE++ NL ++ ++ +S + + + ++D+ND+SP + T +K+V+ E+ K + + + D S NS YT+ V+ + +F ++ D L++ + +DRE+++ L + A D G+P G L+I + D NDN P F +I EN + + Q+ A D DI N ++ +S + + ++ F I+ G I LDY+ + +YL+ ++ D + I+ ++V + NDN PVI + + S V EN T +A +S +D D+ + GG +K VL D S+ I + + LDRET++ F C D G PP+ T K I V D NDC P F + E V + V +NA D D G NS+LVY I + F+ID ++G++ T + DRE+ + L V+DR S P LS + V + D ND P F + Y S+ E S V +LA+D DI N I Y+++ F + P + T +LD E ++F + A D G + +V V + DLNDN P + SS S+ +G+ + LKA+D DS + + I QGN E+F ++ SG + L K + L VK D G N IV I
Sbjct: 12 GVITTKTVLDREKVS-------AYNLTIVEFSTPPKS--YTVLVYVQDLNDNSPSFVRGTSAKLVVF--ENDKDFRQKLIAVDSDFGS---NSTQSYTI--VSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSI--ETHSDPQAIFGIHPTTGVIVNNVRLDYEAK-RSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGS---YQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFD-VLNDESI-----IAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDR----GSPP----LSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDI-GENSLILYSILTP---------NTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVH--VSLTDLNDNQPVFDPSS---YSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVD-GSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNI 691 HSP 2 Score: 172.555 bits (436), Expect = 2.797e-43 Identity = 171/657 (26.03%), Postives = 293/657 (44.60%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSK----IGSRYYLPLAKDLDSSPDNSISRYTLKYVN--NSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH--AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSI----PEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIE----DLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMK 2453
+ I++ D+ND P++++++ I EHS+ IG + + K ++ SIS+ + NS L+ S D + L L V A D G+PPL G ++TI + DINDNSP F + + E+ I + D D +++FS ++ + F ++ G + + +++DY +Y LP+Q D + + +L +KV + ND +PV N S ++E D I + ATD+D+ + + S+ + I + LDRE E + + D G P + ++ + + V D ND PHF A ++ E PV +++ ++ASD D G N + YR D A F +D+ TG + T+ + DRE Y ++V +D T + VI++D+NDC+P F K Y ++ P GSS + +++A D D + N I+Y +V P FS++ + T LDRE H + A D G S++ + IE D+NDN+P + + + + + +G +V + A+DSD G N + Y+I+ GN FK+N+ +G + ++
Sbjct: 689 VNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLY---LQSEVDHEKIPSLYLTVQAK----------------DKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPG----TLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFG-----NWSYTAHVLETTPPDSNII-EVVATDVDSGENGRISYAFDSKVDTSK----FGLRNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQFIVDKQTGKITTSQVLDREAKASYVF--------SIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSS----LLTLIATDDDQQGPNSDITYMIVAGPKA---------FSLNQVTGVLTLVSPLDREVTHRHILHVVASDKG---GNQSLETITYIEINVLDVNDNYPVFINETTFK---TVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTGVISTLR 1285 HSP 3 Score: 168.703 bits (426), Expect = 3.561e-42 Identity = 211/760 (27.76%), Postives = 343/760 (45.13%), Query Frame = 3
Query: 213 IIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKEN-NFVSLVN--GKLFVKADIDRERI-----CTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYI-NGKNGKIFVKQILDYD--QEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLS--VVTKYT--ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCD-VGVNSQLVYRIDHA--HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVV-VKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSG 2435
I L V D P +K+ F ++EHS+ +IG + R D + + + K N + + L+N G L++++++D E+I + LF Y + I++ DIND+SP + S I++ +PE + IG +Y D DS L V+ S L ++N + L+ L N R L + A+D GSPP + + L + + D+ND SPVF + E D + ++ A D+D +N +++++F + + D SKF + NG GKIF+K LD + +E N ++ I + + + V V + NDN PH ++ V+EN T + ++SA+D D S G R T ++ +V K T I ++ LDRE + +I D G P+V + + V D NDC+P F +V ++E +PV S + L A+D D G NS + Y I FS+++ TGVL S DRE T + L D+ + L + T I + + D+ND PVF ++PE V +VLA DSD + N ++ Y +V + + F ++ + +T +LD E + + + A D G + S +V + +ED NDN P + + + I + VT +KA D DSGLNS + Y I + FK+N ++G
Sbjct: 691 ITVLDVNDEPPIFSKA-EYNFTIQEHSQALSVIGHVHAISR----DKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLF----------GYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSG--------VLGRVSFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSAR----SYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKV---DTSKFGLRNG--GKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNN------PHFQQASYAFFVKENEPVATYLGAVSASDSDE---------GSNGHVTYRFDTQVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGG-------NQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSD-QGDNGKVRYKIV-------NGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITW---IYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETG 1385 HSP 4 Score: 137.887 bits (346), Expect = 1.222e-32 Identity = 180/682 (26.39%), Postives = 303/682 (44.43%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD---STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD----NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRE-TNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITH-RVSVDVVVKI--EDLNDNFPQWSHSSDLGLSINIT---REETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTN 2531
+++ + D+ND+SPV+ ++ E + S +A D+DS + IS V+ S+ L N + + + +DRE IE+ L ++A D G+P + S + + + D+NDN+P F + +KEN + YL + A D D N +T+ F + ++F ++ + GKI Q+LD + + +Y+ I TD S + +T + V V++ ND +P S + + V E++ +++ +L ATD D NS + L++V L++V+ PLDRE T+ + G T I I VLD ND P F T + E +P+ S V + A D D G N ++ Y+I + + F I+E TGV+ T D E T Y L + D ++ +S ++ + ++D ND P F K I E V ++ A D D +N +I Y + S + +F ++ + + T +DRE +S + A D R+ +KI +DLNDN P++ +S N+T +E VT + ALD D+G ++ Y I+ + + F L+ K+G L L+ D L + +D G PLT+
Sbjct: 898 LELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGL-------------RNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQV-----AQFIVDKQTGKITTSQVLDREAKA-SYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFS------KNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSLNQVTGVLTLVS--------PLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGK-------KQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDD-SGLNSRIWYTI-------DSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKF-------VSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGK-FSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTS 1523 HSP 5 Score: 120.939 bits (302), Expect = 1.643e-27 Identity = 157/624 (25.16%), Postives = 269/624 (43.11%), Query Frame = 3
Query: 414 NGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISD-NDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEV-NTYLLPIQVTD--STKFAETILLVKVQ--NENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGG-----LKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTT-KIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVF--KKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTK---------ESLDRETYDMHSFSIEAWDSG--PIT 2198
GK+F+K+ +DRE I + L + I + +S+ ++++ ++D+ND++P + Q+ + E+ + + A D D + ++ Y ++Q+ F + + K +Q+L DRE ++A D GS P T +T+ + D+ND SP F K +++ E+ + L + A D D N +T+ M + F +N G + + LD +EV + ++L + +D + ETI +++ + NDN PV +N + V E + + +A++ A D D G K++ T I + LD E + + D G Q T+ +++ I V D ND P F +I E VP+ + VT + A D D G+NS++ Y ID AHF I+ TG+++T DRE+ EY L+ D+ + + L +T +++II+D+ND AP F + L Y + ED E N Q++ + P +T + Y VSPD F+ SLD E ++ I A D G P+T
Sbjct: 965 GGKIFIKSKLDREDI-----EEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVT-----YRFDTQVAQF--IVDKQTGKITTSQVL-------DREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITY-----MIVAGPKAFSLNQVTGVLTLVSPLD--REVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVF-----INETT-FKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTDGTFKINE--------TTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQ-----AFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLTY-----------------VMED---EPFNFQVTSITALDP-DTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLT 1522 HSP 6 Score: 119.783 bits (299), Expect = 3.799e-27 Identity = 170/648 (26.23%), Postives = 279/648 (43.06%), Query Frame = 3
Query: 537 EIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQL--LLRVDANIDRXXXXXXXXXXXXXD-SGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAET----ILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQ---VTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI---DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSL 2441
++ + + D+ND SP ++++K + + E +GS +A D D NS + Y+ + K FS LNQ+ +L + + +DRE + L ++A D G+ L T++ IN+ D+NDN PVF+ T ++ E I + + A D D DN K+ + +N F IN G I + LD+ + N Y+L + TD K + ++ + V++ NDN P P + + EN+ T + ++ A D D+ + + R ++ T I T P+DRE + ++ D + Q T + I + D ND P F + T Y+ E P VT + A D D G + YRI D FS+D TGVL+ D E +Y L + D + S P L+S + V++ D+ND P F + + ++ E V V A D D N +++Y++ S + FS+ + T LDRE D + ++ A S V + + D NDN P++ S + L + E + RL+ L D D G N+ + Y I+ GN F + + +G L
Sbjct: 1104 QVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNS----DITYMIVAGPKAFS-----------LNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKI---VNGNTDGTFKINETTGVISTLRALDF-EVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIIT------WIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDS--QSPRAHFKINSETGL-IQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLT-YVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATD----LGSPP----LTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRD-SGSNAELTYSI-------PSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFI-SPVVTLKV---PENSPARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGEL 1702 HSP 7 Score: 117.472 bits (293), Expect = 1.980e-26 Identity = 146/548 (26.64%), Postives = 241/548 (43.98%), Query Frame = 3
Query: 855 DSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD-----NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIE-AINRQISY---------AMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSG 2435
D GSPPLT + + D+NDN P F + L ++ EN + ++ A D D N +LT+S + + ++ KF I+ +G I ILD +++ +TY L + T + + + T + + V + NDN P I P V L V EN I +L+ D+D I ++ G + R +LS TK LDRET +Q +++ +D P I I + D+ND P F ++ + I E P + + L ASD D G N +VY + + +SID TG++ + + F+ EY D+ DP ++ +R+ I+D N+ AP F K YE I +S V V A D+D + + N +++Y ++ + T S + FS P GR H+ I A D G R V + I ++ D+ P++ + + +S I VG +T ++A + ++ + Y II GN+ F ++ +G
Sbjct: 1515 DLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMD---KFSIDKHSGLIVTNSILDREKK-DTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKF-ISPVV-----TLKVPEN-SPARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTK--------LDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQ----GQDPKMAIVP----VRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGR---------------HALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVS--IPENSKVGSYITTVRA---RASSDAQVTYSIISGNKGRAFYVDPFTG 2015 HSP 8 Score: 111.694 bits (278), Expect = 1.113e-24 Identity = 161/706 (22.80%), Postives = 300/706 (42.49%), Query Frame = 3
Query: 243 MKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSL----VNGK--LFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQL-------LLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST-KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTD-------LSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHA---HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGS--SPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDN---FPQWSHSS 2273
+ ++ ++ +QV E++ IG + + + D D + +N + + + S+ +N + + V +DRE + L I ++ +I++ D+ND +P + + + E++ + + + A D D + +NS+L +++I N+ ++YL+ ++ ++DRE+I ++ L +L D GSPPL+ + + +N+TD NDN P F + S+ EN+ + Q+ A+D DI +N + +S + + F+++ + G + + LD++ + ++Y + TD + + V + + NDN PV + S+ + EN + +I L A D D+ ++R + + SV I L K LDRET + + T+K D G V I+NI VLD ND P F A I E S + ++A D G N+++VY I + + +TG L S D EK L D+ T + + +I DIND +P F +PE + Y SV DS + ++S++++ P L+ S G + TK + ++ ++A D G + + +K+ D+ND F WS+++
Sbjct: 279 IHVSYTLGGSYQVTENATIGTQVARV----SVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRE-----THDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQD-------------FGSNSEL-VYTIA-NTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI-----LTPNTPFFLDPRKGLVTNSRTLDHEVQ-SSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVF------DPSSYSVEYFENTRIGQSICQLKAIDRDSPK-----------FAITRFIIEQGNADEVFSVDGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKG-------TPPLFGYANVTIAVI-DINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLG---RVSFSLLSNP-------GTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTA 919 HSP 9 Score: 107.071 bits (266), Expect = 2.679e-23 Identity = 181/714 (25.35%), Postives = 310/714 (43.42%), Query Frame = 3
Query: 528 NYFEIQISIEDINDHSPVW-TQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKP--LTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXG--GLKLSRV-LTDL----SVVTKYTILLTKP------LDRET--------------NEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVN-SQLVYRIDHA-HFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWS--HSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIR--LVVKVSDSGPSPL-TNTTIV 2543
Y +QI I +I D P + Q+ ++IPE+SK+GS Y+ + SS ++ T ++ ++ + F + + + + +D E + L L+A G L G L IN+ D NDNSP F L +++ F +++ ++ A D+D N K+T+S GN + F I+ G+I ++LD + ++ L I+ TDS K + V V + NDN P+ L VN + E+ + + S+ ATD D S + S+ G+ + RV TD + KY+ +T +D +T + F Q ++ D G PPQ + I + + P F + E + + V + +D G+ ++ Y I+++ +F I + +GV+ N D E + L + D D+ P++ V + + + D+ND PVF + Y EG V +V A D D A N ++ +A+ +S K F++ + T+ +LD ET H S+ A D G V V +++ DLNDN P + +D+ + N+ RL + A D DSG N+ L++ +I G LF +++ SG L + + + L +K +D+G PL +N TI+
Sbjct: 1944 GYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGS--YITTVRARASSD----AQVTYSIISGNKGRAFYV-------DPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGV-----FTIDSTTGEITTAKLLDRETTA-SFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVN-------IREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIITRE----PKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSNYFRIGQRSGVISVNKPLDYETKRRFLLVVSAID-----DTAPSKPV---RVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGA-NGRVWFAI-------QSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNS---RLYEI-NATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITII 2607 HSP 10 Score: 104.76 bits (260), Expect = 1.430e-22 Identity = 148/613 (24.14%), Postives = 267/613 (43.56%), Query Frame = 3
Query: 528 NYFEIQISIEDINDHSPVWTQSKIVINIPEHS-KIGSRYYLPL-AKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMN-----IEDRSKFYINGKNGKIFVK------QILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAP----------VISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKY-------TILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFK-----KLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFS--IEAWDSG--PITHRVSVDVVVKIED 2237
Y + I++ D ND+SP + S ++ + E + R+ + + A D+DS + ++ Y++ N + +F+I +S + +LL DRE +L++ DSG PP + + + + +TD+NDN P+F PL+E++I+E+ + + A D D +LT++ ++ + + +G N +I +DY + +T ++ + T + ++ + + VQ + P +I+ P + V EN T++ ++ TD ++ GL L R+ ++ + I + KPLD ET F + DD P + + I V D ND P F + EG+PV + V ++A+D D G N ++ + I D F+ID TGV+RT D E + + D S P +S T IRV+ D+ND PVF+ + ++P S R+Y + A D D A N ++S+ ++ + F + TT + D E ++ +S I+A D+G P++ +++ V V ED
Sbjct: 2049 GYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVT-YSIWTGN--EAGVFTI--DSTTGEITTAKLL-------DRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLF-DPLSEVNIREDTRTGAVVTSVVATDTD--KESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIITREPKFELPSYFGKVPENAMMGTSVLTVRVTD------------NAAGLPLGRISYNIENSNYFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDE----GSPPMHTDVSVT--IRVL--DLNDNPPVFRVPGPNDVQVLENLPLNS--RLY--EINATDRDSGA-NARLSFTVI-------GGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADED 2614 HSP 11 Score: 102.834 bits (255), Expect = 5.439e-22 Identity = 135/529 (25.52%), Postives = 227/529 (42.91%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLD------------SSPDNSISRYTLK---YVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDAN---------ID-RXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGN-SMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETI---LLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPA-AITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSD 2006
+S ++++ + D+ND+ P++ V NI E ++ G+ +A D D S+P +I R + +N+Q+K + NS +Q+ ++DA+ ID R + I++ + A D G PP ++ I IT P F P + EN + + + D + G S NIE+ + F I ++G I V + LDY+ + +LL + D T ++ + + + V + ND PV S + E I T + ++SA D D+ + + G D I + LD ET + +++ D+G PP T + I+VLD ND P F V + E +P+ S + ++NA+D D G N++L + + F ID+ +G L TN FD E T Y+ T+ +D LSS I V + D ++ P F ++ Y+F +P + +VG V A D D
Sbjct: 2154 KSTNCQVKVVVTDLNDNPPLFDPLSEV-NIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNS-------DQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIIT----REPKFELPSYFGKVPENAMMGTSVLTVRVTD------NAAGLPLGRISYNIENSNYFRIGQRSGVISVNKPLDYETK-RRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFG------QSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKT---GVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKA------TDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRD 2648 HSP 12 Score: 68.9366 bits (167), Expect = 1.132e-11 Identity = 67/277 (24.19%), Postives = 121/277 (43.68%), Query Frame = 3
Query: 897 INITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTK--PLDRETNEFFQ--ATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVY 1706
IN++D+ND PVF + E + + + A D D N ++ F+ + +D+ F I+ K G I ++ LD+ + + T+ + ++ TD + + ++V + NDN PV + N + V EN+ + + ++ATD D+ + + GG L D K++ LT D E +Q TIK D G PP + I + V D+++ P F + + FV ++ A+D D G ++ +
Sbjct: 2395 INVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSG---DDKGSFAIDRKTGVIRTQRALDH-ETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRV-----PGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLID-----KFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRVFF 2657 HSP 13 Score: 50.8322 bits (120), Expect = 4.109e-6 Identity = 78/292 (26.71%), Postives = 132/292 (45.21%), Query Frame = 3
Query: 1731 IDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYV--------GSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIF------TTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI-IQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIR---LVVKVSDSGPS-PLTNTTIVRI 2549
++ N GV+ T ++ DREK Y L + S P + S T++ V ++D+ND +P F + G+S ++ V ++A DSD + + Q SY +V ++ KL DG ++ + +DRE D + +I A D G + + + + +ED NDN P++S+ S G I VG + + A D D G N+ + Y I + +F ++ +G ++ + D E R +VVK D G S L+++ IVRI
Sbjct: 7 LEYNAGVITTKTVLDREKVSAYNLTIVEF-------STPPK----SYTVL-VYVQDLNDNSPSFVR---------GTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQ-SYTIV---SGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSG---TIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTG---VIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRI 267
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO30364 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T100]) HSP 1 Score: 166.777 bits (421), Expect = 1.238e-41 Identity = 187/730 (25.62%), Postives = 329/730 (45.07%), Query Frame = 3
Query: 411 VNGKLFVKADIDRERICTKKNQCCCLNLFVIVYN-LKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVD---ANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMD-NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISK----LYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVS-VDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRI 2549
V G++ A++DRE + + LFV + + + S+ ++ + +ED+ND+ PV++ I E S G+ A D D + ++ L+SIV N + D +N + + + +DRE E + A DSG P + + + I + DINDNSPVF ++EN + + A D D+ N KL++ + ++F I+ G I ++ L+ +E +Y L ++ DS + T +++ V + ND+ +P S V E+++ + ++ TD D N + + SSG L + + + + T LDRE N + I +D G P + + I + D ND P F ++ V + E V +++ V ++ A+D D G N Q Y+I F ID NTG++ + D EKT Y L + D + + P L+ + + + D++D APVF K Y + E + +V +V A D D EA ++++ Y + ++ I + + + +P G L+RET+ + + A +T + S V V+ + D+NDN P++ S + + T T ++TV KA D D G + + + I+ GNE+ +F+++ K+G L + D LVV D G L+++ V I
Sbjct: 1243 VTGEIRTVAELDRENVTQYE-------LFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDAD--------------IGDNAAVLYSIVEN-VTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVL----YTRFAIDPDTGNITTREPLNR-EETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDH------VPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFSVNETTGIIS----TTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQD----LGTPP----LTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQSGVITLNCTPSG-------CLNRETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTV-KAQDGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNI 1919 HSP 2 Score: 166.007 bits (419), Expect = 2.271e-41 Identity = 182/681 (26.73%), Postives = 297/681 (43.61%), Query Frame = 3
Query: 561 INDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLF------SIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQE-VNTYLLPIQVTDSTKFAETIL--LVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTD---LSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLK--AXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIY 2552
IND SP++ +S +N+ E + G + + + + D I+ N ++ K + I+ +S D+ + N +L V A +G+ T H+T+ TD+ D+ P F + + EN I + ++ A D DI D + + G+ + F I+ G+I + + + D+E V Y L +Q DS +L +V+V++ NDN PV S+ + + E + T+I + A D D + +TD ++ +T L + LDRE E+F TI+ D G P + +T + I+++D ND +P F Y+ E P + V + ASD DVG N++L Y + + F+ID +TG + T +RE+TG Y L L D + TT + + + D ND P F + Y FS+ E VG V D DI N ++ Y + S + L FSV+ I +T +LDRE ++ I A D G + V++ IED+NDN P +S S N+T E+V V++ A D D G N Y+I G+ ++F ++ +G + + + + L V D G PLT V I+
Sbjct: 1082 INDESPLFEKSMYYVNVSESASRG----IVIGRVTATDRDEGINAIIFYSSNGAEAKFYVSRSTGDIIVDSPLDREFKNVYILNVTA--------------ANIVAGAQDTTTQVHITV--TDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDTISYSIANGDPYGL-----FTIDNVTGEI--RTVAELDRENVTQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYT------IEYWEESPEGTSILQVKAIDADIGDNAAVL------YSIVENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYTRFAIDPDTGNITTREPLNREETGSYTL--------TLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDIND-NARVRYYI-------SSGNTSLMFSVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKS-----VYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIH 1702 HSP 3 Score: 121.324 bits (303), Expect = 1.160e-27 Identity = 144/545 (26.42%), Postives = 232/545 (42.57%), Query Frame = 3
Query: 891 LTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD---STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETA-----IASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF---PA---AITTVYIDEG-VPVESFVTKLNASDCDVGVNSQLVYRI---DHAHFSIDENTGVLRTNSIFDREK---------TGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFS-IEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSL 2441
+T+ + D+NDN P F I EN + Q+ A D D +N +L+F+ +D F ING +G + + LD + + TY L + D S++ L V V +ENDN P I+ + L + NI + ++S++A D D S S SGG SR L+ T + LDRE + + I D+G PP + +++ +LD ND TP F PA A + +DEG + + +NA+D D N ++ Y + +H F +D TG L DRE G + L+ T D+ + P S+T + + ++D ND +P F+ YE + E + P V V A D D+E + I Y + K + KL Y+ H + + +S R VV+ ++D+NDN P ++ S + ++ G V + A D D G N + Y++ GN+ + F +N +G +
Sbjct: 480 VTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAG---DDGGHFSING-SGLVTTARELDR-ETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQIT---------DGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGD--SRFT--LNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEHGFFRLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQ-----ATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVI-YNITDGDENRKCEVEKLV------------------RHYNWHKKNCVLCKESKCSVERTY--VVIYVDDVNDNDPVFNQSK---YAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEI 977 HSP 4 Score: 115.931 bits (289), Expect = 5.778e-26 Identity = 178/683 (26.06%), Postives = 281/683 (41.14%), Query Frame = 3
Query: 522 QSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTF--SFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFA---ETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLT--KPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVY-RIDHAH----FSIDENTGVLRTN----SIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSP--RMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGL---SINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSD 2507
+S+ + I + DIND+SPV+ + + E+ G+ + A D D + +S YV L ++Y + R N RE+ L L A DS G+T + I +TD ND+ P F + S++E+ + + ++ D DI+DN ++ + S GN+ + F +N G I LD +Q +Y L I D A T +++ +++ NDN P+ S S NV L E++ +T + + ATD D + + G D+ + T L+T LD E + T+ QD G PP + I V D +D P F + + E V V +NA+D D + + VY RI+ + F I E +GV+ N +RE Y+L+ R NL TE+ +I V+ D+ND AP F Y S+ E + P + +V A+D D E + +I + +V S F + + T LDRE +S + A D G SV V + + D+NDN P D+ + + +E + V V D + + Y I E + F LN+ SG L D + L VK S+
Sbjct: 1379 KSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLS-----YV------LSGVLYTRFAIDPDTGNITTREPLN--REETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLM-----FSVNETTGIISTTSTLDREQNA-SYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFS-----KSVYNVTL-RESVFLKTQVVQVIATDPDEGANGQFTYKITAGDT-----DDVFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTDSMFLIGEQSGVITLNCTPSGCLNRETHARYELQVAAISRVNL-----TEQKSLVPAVITVL--DVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGD-EGESGEIIFTIV-------SGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAAQDLDTKNLIYYYITNTEEQKYFILNETSGELRTRITLDREDSSVHYLYVKASN 2016 HSP 5 Score: 105.531 bits (262), Expect = 9.171e-23 Identity = 209/819 (25.52%), Postives = 344/819 (42.00%), Query Frame = 3
Query: 204 SKFIIFLIVVDFPMKMAKSISLQFQVK--EHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENN------FVSL--VNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNL---KIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDK-------LTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVN-------------------------TYLLPIQVTDSTKF-AETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSV-VTKYTILLTKPLDRETNEFFQATIKCQDDG-YPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAP-VFKKLFYEFSIPEGSSP-RMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSIN-ITREE---TVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIR 2486
SKF FLIV D+ + K E++ +G I +I D N Q N F SL VNG+L + +D E L VI +L K++S I I + DI+D P + QS + I E++ IGS A+D D +N I + ++ + +F+I N+ ++ V+ +ID EK + + + A + P + + + + D+NDN P FL+ + ++E+ + ++ + L ++D DK L G D KF I+ +G +++ + LDY++++N ++ + S KF A + + + N NDN P+ + SS N + EE I T IA ++ATD D + GG SV TI + LD +T +Q ++ +D G + ++ + + + D ND P F T I E +P + V ++ A+D D G N +L + I D HFSI+ +G++ T DRE Y L + YD V S L+ V + D ND P + L +I EG+ + + S+ A D D + N Q++Y+M S + S GR+ + LDRE D + I D+G + S V V I D+NDN P + + L+ IT +E T+ + + + A D D+ N + Y + G+EH F+L+ +G L + K+ P++ R
Sbjct: 29 SKFF-FLIVDDYNDNAPVFTEQPYMAKIAENARVGTTI------LKISAIDADSGTNSQVQYKFSNATATQTPFFSLNSVNGELTLGGPLDFE-------VARSYMLVVIAEDLGVPKLESRTTVI-IEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPI---LYEIISGNSDGVFTIDSNTG---------VITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALP---GRVVSDQLQVTDGDKNPVFRRVLYHLVG-----ADSDKFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSEKFSANASVTLTLINVNDNKPMFA-----KSSYNYTMDEE-ITPGTHIADITATDADLGTFGALTYELRGGQAAY-----FSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGHFSIN-GSGLVTTARELDRETIATYTLTVSAYDHG--VSSRHKHVQLT------VNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGS-NGQLTYSM--------SGGDSRFTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSL-SGDEHGFFRLDPVTGELSVRKELDRESPQMSR 782 HSP 6 Score: 103.605 bits (257), Expect = 2.828e-22 Identity = 131/516 (25.39%), Postives = 225/516 (43.60%), Query Frame = 3
Query: 903 ITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAE---TILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDM---DNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIK--DINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQ 2426
IT IND SP+F K + +++ E+ + ++ A D D N + +S + +KFY++ G I V LD + + N Y+L + + A+ T + + V + VI P+ NSS+ + + EN T + ++A D D S I+ G + V ++ V + LDRE ++ ++ +D K++ +QV D ND P F T+ E P + + ++ A D D+G N+ ++Y I ++ T + N+I G +L+ V + N V S ++ V IK DIND +PVF Y + E V V A D D+ N ++SY + S + F++ PD TT+E L+RE ++ ++ A DS + V++ + D ND+ PQ++ S G + ++ + VG V + D D N+ + Y I GN +F +N+
Sbjct: 1079 ITLINDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYSSNGA-----EAKFYVSRSTGDIIVDSPLDREFK-NVYILNVTAANIVAGAQDTTTQVHITVTD------VIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDTISYSIANGDPYGLFTIDNVTGEIRTVAE--------LDRENVTQYELFVQAKDSVNLVSDLLKVV-VQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSI------VENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDV-GTNAKLSYVL--------SGVLYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQS---GYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFSVNE 1555 HSP 7 Score: 98.9821 bits (245), Expect = 8.283e-21 Identity = 154/623 (24.72%), Postives = 255/623 (40.93%), Query Frame = 3
Query: 540 IQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLT-EISIKENNFIDQYLCQMFAK-DLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEV-NTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQD-ETAIASLSATDMDNXXXXXXXXXXXGG----LKLSRVLTDLSVVTKYTILLTKPLDRETNEF---------FQATIKCQDDGYP---PQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG-PITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVL 2336
+ ++++D+ND+ P +T +I E+ G+ + A D DS + R + FSI + L + +DRE I L + A D G LT+N+ D NDN+P LT +I E L A D D N +LT+S S+F +N G++ + D+E+ ++Y L I VTD+ T + V + + NDN P P + + V+ V+E + ++ATD D + S SG +L V +LSV K LDRE+ + F I D P + T ++I V D ND +P F + + E S V +++A+D D+ +++Y I DEN R+ E + + ++N V ++ + T ++ + + D+ND PVF + Y + E S V V A D D + N +I+Y + + I+ + ++ G I DRE +++A D G P + + +VV+ ++D NDNFPQ+S + G I VG +T++
Sbjct: 480 VTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGEN---GRLSFNISAGDDGGHFSINGSGL----------VTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGG-----DSRFTLNSATGRLQISPT-GLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEHGFFRLDPVTGELSV--------RKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDG----DEN-----------RKCEVEKLVRHYNWHKKNCVLCKESKCSVERTYVV-IYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRD-QGANGKITYKLTNGNKDDAFSINNVTGEITVAGVI-------DREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSFT---GYEGEIAENSPVGSTITMV 1048 HSP 8 Score: 96.2857 bits (238), Expect = 6.206e-20 Identity = 136/540 (25.19%), Postives = 229/540 (42.41%), Query Frame = 3
Query: 273 FQVKEHSEIGLLIG-------DLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFV----KQILDYDQEVNTYLLPIQVTDSTKFAETILLV----KVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTD--LSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHF--------PAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-----DHAHFSIDENTGVLRTNSIFDREKTGEYKL 1802
F V+E ++G +G D+ +N R++ + S +L F V+ G + + +DRE +N L + + + + + I+IED+ND+ P++++S + + E + ++ +A D D + ++T K +F I N+ L+ + A +D EK L + A+D G+PPLTG+ + I+++D++DN+PVF KP + EN ++ + A D+D + K + S N + S F I ++G I + L+ + Y L + E LV V + NDNAP +V S VL I D T I ++ A D D + + G + D V+T+ T+PLDRE F+ + +D G P ++ +NI VLD ND P P TT + E + V + A D D L+Y + +F ++E +G LRT DRE + + L
Sbjct: 1510 FSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFS-------VNETTGIISTTSTLDRE-----QNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGAN---GQFTYKITAGDTDDVFYIDANTG---------LITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTD--SMFLIGEQSGVITLNCTPSGCLNRETHAR-YELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRS---VLEDTGPITDAT-ILTVKAQDGDEGESGEIIFTIVSGNENGVFQMDNKTGVLTR-----TRPLDREDTSFYSLVVMAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAAQDLDT---KNLIYYYITNTEEQKYFILNETSGELRTRITLDREDSSVHYL 2010 HSP 9 Score: 89.7373 bits (221), Expect = 5.177e-18 Identity = 187/830 (22.53%), Postives = 326/830 (39.28%), Query Frame = 3
Query: 303 LLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSL-VNGKLFVKA--DIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIE--DINDHSPVWTQS-KIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVF----LKPLTE--ISIKEN-NFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYD--------QEVNTYLLPIQVTDST------KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH----FSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEG-----------------------SSPR---------------------------MY-------------VGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDS 2510
L G +V D D L+F + ++ +NG V ++DRE I T L V Y+ + S + +Q+++ D ND++P T I NI E + G+ +A PD S L Y + F++ NS + ++ +DRE + +L++ D+GSPP T ST + + I D+NDN+P F + L I++ E I++ L + A D D N K+ +S ++ F ++ G++ V++ LD + Q +LL I TD K A + + V++ NDN+ P S N + E + + + +SATD D +V+ +++ + + L R N + + C++ + T +I + D ND P F + + E P + V +++ASD D G N ++ Y++ + + FSI+ TG + + DRE + L D+ +P+ + + +I V KD ND P F YE I E SSPR MY +G V A D D E IN I Y+ S+ ++ F VS LDRE +++ ++ A + + V + + D+ D+ P ++ SS L++ ++ ++G VT + A D + +++Y I G+ + LF ++ +G + + + + L V+ DS
Sbjct: 507 LPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGHFSINGSGLVTTARELDRETIAT-------YTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAA---VDPDAG-SNGQLTYSMSGGDSRFTL--NSATGRLQISP------TGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSG----DEHGFFRLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNS------PQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYK-------------GKVIYNITDGDENRKCEVEKLVRHYNWHKKNCVLCKESKCSVERTYVVIYVD--DVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQ-----GEPSSRKTFAEVVITV--KDENDNFPQFSFTGYEGEIAENSPVGSTITMVPDQKISSSTLRPRSSPRAPAALLTAREKRPITLINDESPLFEKSMYYVNVSESASRGIVIGRVTATDRD-EGINAIIFYS---------SNGAEAKFYVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSS---LTVKLSENASIGTNVTKITA--LDKDIGDTISYSIANGDPYGLFTIDNVTGEIRTVAELDRENVTQYELFVQAKDS 1270 HSP 10 Score: 82.0333 bits (201), Expect = 1.179e-15 Identity = 124/553 (22.42%), Postives = 233/553 (42.13%), Query Frame = 3
Query: 855 DSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD---STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYI-----DEGVPVESFVTKLNASDCDVG-VNSQLVYRI---DHAHFSIDENTGVLRTNSIFDREKTGEYKLE---------ATVYDRRN--------LVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSV-DVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLN 2423
+ G GS + + D NDN+PVF + I EN + + ++ A D D N ++ + F N+ + F +N NG++ + LD+ + +Y+L + D + T ++++V + +D + P S + +EEN + + ++ A D D G D + I + +D E + F+ T+K + P + V+ D + PA + +VYI D +P +L +D D V +++Y + D F+ID +G L N D EK + + + +D ++D +EK ++ ++ +I ++ND P+F K Y +++ E +P ++ + A D+D+ A+ YE + YFSV+ D + + LD +T + FS+ D G +++ V V ++D+NDN P+++ + + +I G +V + A D DSG N L++ I G++ F +N
Sbjct: 20 NGGGLARRGSKFFFLIVDDYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKFSNATATQ-TPFFSLNSVNGELTLGGPLDF-EVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISD------MPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILYEIISGNSDGVFTIDSNT---GVITVNGSIDAEKTDVFRITVKASE---VPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSDKFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSEKFSANASVTLTLI-NVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFG-----ALT---YELRGG-QAAYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQDVNDNDPEFTG---MPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDDGGHFSIN 545
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 166.392 bits (420), Expect = 2.025e-41 Identity = 194/743 (26.11%), Postives = 325/743 (43.74%), Query Frame = 3
Query: 309 IGDLVENYRIQDFDLSRRENLNFQMMKEN--NFVSL--VNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQS---NYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSV-VTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI-----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPL-SNDPEIIRLVV 2495
+ LV R D D + F+++ N NF S+ +NG++ VK +D E I NL V + K Q N + I++ D+ND++P + S IPE+ +G +Y A D D + I+ FS + N LP N + + +DREK+ K + A D G P G+ +TI + DINDN P F + SI EN+ + Q+ A D D S + +S +S DR F IN + G I + L+Y+ + + Y+ + +D + ++ V V + N +AP + V+E+ T++ ++ ATD D S ++ ++ + SV T I LDRE + ++ + D G P + I + D ND P F + E + V +++ASD D+G N+Q++Y F+ID G++RT DRE EY+L D+ + P + ++ ++VI++D+ D P+F+K YE ++PE + PR V +V A+ D+ + Y++V S F ++P+ T LD ET + ++ A S T V+V ++D+NDN P +NI +E K D ++ L +++++GN E LN SG L + K+ + ++ P I++ V
Sbjct: 249 VNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGV-------FNLLVTAQD-KGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEIT--------------FSFMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPD-SGPTNVVYSIVSSSG-HDRC-FRINPQ-GLITLSCTLNYNTK-HVYVFSVSASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAE------VKEDASLGTSVLTVLATDRDTGSNAKIS------YSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQ----GTPPGQ----ASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSP-ETGMMYSIV-------RGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRATLSPFFTE---TTVMVYLKDINDNTPVLE-----AFHMNINVQEGKVPPEARYKIPAYDPDVSDKLTFKVMEGNAKEWVTLNATSGELSVNKKLIQASKPANIKIAV 928 HSP 2 Score: 142.124 bits (357), Expect = 5.214e-34 Identity = 165/587 (28.11%), Postives = 263/587 (44.80%), Query Frame = 3
Query: 528 NYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSF--GNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSV-VTKYT--ILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATV-YDRRN--LVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFP 2255
Y ++ I++ D+ND+ P++ ++ +IPE IG A D DS + + L ++ FSI S + V +DREK+ L + A+D G+PP + + + I + D+ND +P F K + +I+E+ ++Q + + A D D N ++ F GN MN F IN NG++ VKQ LDY+ + + L + D + + +T + + + + NDNA P SS+ ++ EN + A D D+ ++G + S + DL + + T I + + LDRE F IK +D G P + T I I +LD ND P F I E + V ++ A D D G + +VY SI ++G R F G L T+ Y+ ++ + ++ +LSST ++ V + D N AP FK+ Y + E +S V +VLA D D + N +ISY++ E FSV + T SLDRE D + F + A D G + V + I D+NDN P
Sbjct: 110 GYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILN--SDGDNSAFSIGEVSGA---------VTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNF-----FSINRINGEVRVKQKLDYEM-IGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNA------PQFVSSHFQTMIPENYAVGQEFYRVQAYDKDH--------GTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSG-PTNVVY-------SIVSSSGHDR---CFRINPQGLITLSCTLNYNTKHVYVFSVSASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGS-NAKISYSIATLVPE---------FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDP 644 HSP 3 Score: 130.954 bits (328), Expect = 1.432e-30 Identity = 118/461 (25.60%), Postives = 200/461 (43.38%), Query Frame = 3
Query: 918 DNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTK---FAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIA----SLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI----DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSH 2267
+N P F + + S+ E+ + + + A D D N + +S S N+ + F I+ G I K+ LD + ++ + ++ D + L + V + NDN P+ N+ + I ++ +I ++ A+D D+ S + + V T++ K LDRE + ++ QD G PP+ T + I +LD NDCTP F + + I E VPV VT + A+DCD G N ++ + I D FSI+ G +R D E G + L T D+ + L + T + + + D+ND AP F ++ IPE + V A D D N +I+++ + + L FS++ + + KE LDRE +F I+A D G + + + + D+NDN P++S
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLD-REFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFE--------RNIYAAD--IPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVM--KKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDK--------GQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKD-HGTNGEITFSFM---------QNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQ 444 HSP 4 Score: 120.939 bits (302), Expect = 1.669e-27 Identity = 172/662 (25.98%), Postives = 284/662 (42.90%), Query Frame = 3
Query: 606 NIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDST---KFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGG-----LKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRI--DHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEII---RLVVKVSDSGPSPLTNTTIVRIY 2552
++ E +++G+ A D DS N + RY++ N L S Y S+ T + + +DRE +++ + AED G P L G LTIN+ D+NDN P+F + + I E+ I ++ + A D D N ++ + NS D S F I +G + V + LD ++V TY L +Q D + A + + + + ND P S V S+ + E++ + ++ ATD D S G ++R+ ++ V K LD E F + QD G P ++I ++D ND P F ++ I E V ++ A D D G N ++ + + FSI+ENTG + DREK ++ D+ P ++ T I + + DIND P F + Y SI E S V V A D D N + Y++V + F ++P G I T +L+ T ++ FS+ A D G ++ + V V + D N + P++ S S + + ++G V + A D D+G N+ ++Y I F +++ +G ++K S D E + R V +D G L + V I+
Sbjct: 28 SVSEDAEVGTVVATVSASDPDSG-SNGMIRYSMSPSQN----LMSATYFSIDQITGV----ITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDG--DNSAFSIGEVSGAVTVMKKLD-REKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFS--KKVYSAT----IREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQK--------LDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDK-----GVPFKE---GTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTN--VVYSIVSSSGHDRC------FRINPQGLI-TLSCTLNYNTKHVYVFSVSASD-GMLSS--TALVYVNVTDSNTHAPEFKRRS---YSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI--ATLVPEFSVDETTG---VIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIH 635
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 226.483 bits (576), Expect = 1.633e-60 Identity = 227/801 (28.34%), Postives = 370/801 (46.19%), Query Frame = 3
Query: 264 SLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFV-KADIDRE--RICTK--KNQCCCLNLFVIVYNL--KIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT---YLLPIQVTDSTKFAETILLVKVQNENDNAPVISI--LPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLS-RVLTDLSV--VTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTV-YIDEGVPVESFVTKLNASDCDVGVNSQLVYRID-----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKE---------SLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKL 2576
S+ ++V+E LIG L ++ + D + + ++ V G +F + IDRE R C K + C L V V +L E +I ++DIND++P + S + I++PE++ +G+ + +PLA D DS N ++ Y L ++ V + K L QL+ V N+DRE + +L + A D G+P L + +TD NDNSP F P E + EN+ + + Q+ A D D+ N ++ +S +++ + I+ G I+VK LD +E+N+ Y++ K ++T + ++V ++NDNAP + I + V S + + E++ TA+A + +D D + +G + R +D + KY + T PLD E + ++ I D G P +T + +QV D ND +P F I V + +E P E+ + + A+D D G N++L Y I F ID NTG ++ + DRE Y+ T D+ P K ++T +I+V+ D ND P F Y FS+ E P VG V D D K + ++ SV PDG F + S DRE ++F ++A D G V V + + D NDN P + S+ ++ + V V++A D DSG N+ L + I GN ++LF+++ SG + L K+ + RLVV+VSD G P T +V IY + +S +
Sbjct: 23 SILYRVQEEQPPNTLIGSLAADHGLPDSGHLYKLEVGAPYLR----VDGKTGDIFTTEIPIDRETLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSE-RNGVADYALTAGPDAATLFGLQVADDRGGK--LPQLI--VLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPK-LLRIDRTTGIIYVKGPLDR-EEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETIL-DVTATDADSGTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADK-----GSPVHKG-TATVVIKVL--DCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMD-------------------KGENAHVHLSVEPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNSSFR-QLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNETISNV 783 HSP 2 Score: 62.3882 bits (150), Expect = 2.563e-9 Identity = 96/352 (27.27%), Postives = 153/352 (43.47%), Query Frame = 3
Query: 1596 PAAITTVY-IDEGVPVESFVTKLNASDCDVGV-NSQLVYRID--HAHFSIDENTGVLRTNSI-FDREKTGEYKLEATVYDRRNLVDSDPT--EKVLSSTTII----------RVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRI--FTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEH--ELFKLNQKSGSLYLMKQPLSNDPEI--IRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPA 2582
PA + +Y + E P + + L A D G+ +S +Y+++ + +D TG + T I DRE T+ D R+LV P E +S T ++ R+ ++DIND P F S+PE + LA D D E N YA+ P + + L + G++ +LDRE D + +I+A D G + V + D NDN P++ H S ++ VG V +KA DSD G N + Y + Q + +L ++++ +G +Y+ K PL + EI + V D GP P ++ T V I + PA
Sbjct: 19 PAKGSILYRVQEEQPPNTLIGSLAA---DHGLPDSGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRE---------TLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSER-NGVADYALTAGP--DAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPS---YEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYV-KGPLDRE-EINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPA 350
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 226.483 bits (576), Expect = 4.495e-60 Identity = 226/801 (28.21%), Postives = 370/801 (46.19%), Query Frame = 3
Query: 264 SLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFV-KADIDRE--RICTK--KNQCCCLNLFVIVYNL--KIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNT---YLLPIQVTDSTKFAETILLVKVQNENDNAPVISI--LPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLS-RVLTDLSV--VTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTV-YIDEGVPVESFVTKLNASDCDVGVNSQLVYRID-----HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKE---------SLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKL 2576
S+ ++V+E LIG L ++ + D + + ++ V G +F + IDRE R C K + C L V V +L E +I ++DIND++P + S + I++PE++ +G+ + +PLA D DS N ++ Y L ++ V + K L QL+ V N+DRE + +L + A D G+P L + +TD NDNSP F P E + EN+ + + Q+ A D D+ N ++ +S +++ + I+ G I+VK LD +E+N+ Y++ K ++T + ++V ++NDNAP + I + V S + + E++ TA+A + +D D + +G + R +D + KY + T PLD E + ++ I D G P +T + +QV D ND +P F I V + +E P E+ + + A+D D G N++L Y I F ID NTG ++ + DRE Y+ T D+ + V ++T +I+V+ D ND P F Y FS+ E P VG V D D K + ++ SV PDG F + S DRE ++F ++A D G V V + + D NDN P + S+ ++ + V V++A D DSG N+ L + I GN ++LF+++ SG + L K+ + RLVV+VSD G P T +V IY + +S +
Sbjct: 100 SILYRVQEEQPPNTLIGSLAADHGLPDSGHLYKLEVGAPYLR----VDGKTGDIFTTEIPIDRETLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSE-RNGVADYALTAGPDAATLFGLQVADDRGGK--LPQLI--VLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPK-LLRIDRTTGIIYVKGPLDR-EEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETIL-DVTATDADSGTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKG------TATVVIKVL--DCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMD-------------------KGENAHVHLSVEPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNSSFR-QLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNETISNV 860 HSP 2 Score: 62.3882 bits (150), Expect = 3.175e-9 Identity = 96/352 (27.27%), Postives = 153/352 (43.47%), Query Frame = 3
Query: 1596 PAAITTVY-IDEGVPVESFVTKLNASDCDVGV-NSQLVYRID--HAHFSIDENTGVLRTNSI-FDREKTGEYKLEATVYDRRNLVDSDPT--EKVLSSTTII----------RVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRI--FTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEH--ELFKLNQKSGSLYLMKQPLSNDPEI--IRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPA 2582
PA + +Y + E P + + L A D G+ +S +Y+++ + +D TG + T I DRE T+ D R+LV P E +S T ++ R+ ++DIND P F S+PE + LA D D E N YA+ P + + L + G++ +LDRE D + +I+A D G + V + D NDN P++ H S ++ VG V +KA DSD G N + Y + Q + +L ++++ +G +Y+ K PL + EI + V D GP P ++ T V I + PA
Sbjct: 96 PAKGSILYRVQEEQPPNTLIGSLAA---DHGLPDSGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRE---------TLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSER-NGVADYALTAGP--DAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPS---YEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYV-KGPLDRE-EINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPA 427
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh11 (protocadherin-11 X-linked [Source:NCBI gene;Acc:101161492]) HSP 1 Score: 224.557 bits (571), Expect = 7.728e-60 Identity = 230/824 (27.91%), Postives = 379/824 (46.00%), Query Frame = 3
Query: 369 LNFQMMKENNFVSLV-----NGKLFV-KADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTL-KYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETV-GRLVTVLKAXXXXXXXXXXXXYEIIQGNE-------HELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS-------------KLPAESRFFEKD--------LVVMICMITVTLIVSGILVVAI-VLLKCKHCYRN 2705
L F+ + + V LV G++F IDRE++C+ + C + V V +I +I+ IED+ND++P++ + I I+IPE++ I +RY +P A D D N I Y L K V L + P+ QL+ V N+DREK + + + ED G+PP + + L + I+D+NDN P+F E+S+ EN + Q+ A D D N ++ F+F N ++ + F IN G I VKQ LD + L+ + + + ++V V + NDN P I +N N +L+ EN T IA ++ TD D + + +L V D ++ + PLD ET + I D G PP T+ ++ I++ D+ND P FP + I E + + K++A+D D G N++++Y + F ID +G+L DREK + D S P L S +R+I++D+ND +P F Y F +PE VG + D+D N I+ +++ K F + P + + DRE ++F ++A D G V + + D+NDN P + S S ++ R T G +VT + A+D+D+G+N+ L Y II LF +++ SG++ L ++ + D + RLVVKV D G P L T+V ++ + VS + P + + + ++V+I +I T+ V ILV+ + L++C+ R+
Sbjct: 61 LQFKPVYKTGDVPLVRVEANTGEIFTTNHRIDREKLCSGVFTEKRCYYEIEVAVLPDEI-FRLVKIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVG-INGIQNYELVKSVTEFGLDIIET-----PEGDKWPQLI--VQQNLDREKRDTFVMKIKVEDGGNPPKSSTAILQVTISDVNDNRPIFQDSELEVSVPENAPTGTSVAQLHATDADWGSNAQIHFAFSNQISSSTKRHFAINSSTGLITVKQPLDREVTPVHKLIVLASDGGSTPSRATVIVNVTDVNDNVPAIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVPFRLKPVFND-----QFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNAPIFPQPEIQLSIPENNDPSTQLIKISATDADSGSNAEIIYTLGPDAPDGFHIDRRSGILSVGKRLDREKQERFSFIVIARDN----GSTP----LQSNVTVRLIVQDLNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDAD-AGDNAAITLSIL---------NGKDNFIIDPQTGVIKPNITFDREQQSSYTFMVKAIDGGQPPTSSYAKVTINVVDVNDNRPVFVIPSS-NYSYDLVRTTTTPGAVVTRVFAIDNDTGMNAELQYSIISSIIITSRVSPRGLFTIDKISGNITLQEKIVGADLGLHRLVVKVRDLGQPESLQAITLVHLFVNDTVSNATFIQEQLRKSMETPLDRNIGDSEVTPQANGYVIVVIAIIAGTMTV--ILVIFVTALVRCRQTPRH 849
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh11 (protocadherin-11 X-linked [Source:NCBI gene;Acc:101161492]) HSP 1 Score: 224.942 bits (572), Expect = 9.628e-60 Identity = 230/824 (27.91%), Postives = 379/824 (46.00%), Query Frame = 3
Query: 369 LNFQMMKENNFVSLV-----NGKLFV-KADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTL-KYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL--KLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETV-GRLVTVLKAXXXXXXXXXXXXYEIIQGNE-------HELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSG-PSPLTNTTIVRIYFHSEVS-------------KLPAESRFFEKD--------LVVMICMITVTLIVSGILVVAI-VLLKCKHCYRN 2705
L F+ + + V LV G++F IDRE++C+ + C + V V +I +I+ IED+ND++P++ + I I+IPE++ I +RY +P A D D N I Y L K V L + P+ QL+ V N+DREK + + + ED G+PP + + L + I+D+NDN P+F E+S+ EN + Q+ A D D N ++ F+F N ++ + F IN G I VKQ LD + L+ + + + ++V V + NDN P I +N N +L+ EN T IA ++ TD D + + +L V D ++ + PLD ET + I D G PP T+ ++ I++ D+ND P FP + I E + + K++A+D D G N++++Y + F ID +G+L DREK + D S P L S +R+I++D+ND +P F Y F +PE VG + D+D N I+ +++ K F + P + + DRE ++F ++A D G V + + D+NDN P + S S ++ R T G +VT + A+D+D+G+N+ L Y II LF +++ SG++ L ++ + D + RLVVKV D G P L T+V ++ + VS + P + + + ++V+I +I T+ V ILV+ + L++C+ R+
Sbjct: 61 LQFKPVYKTGDVPLVRVEANTGEIFTTNHRIDREKLCSGVFTEKRCYYEIEVAVLPDEI-FRLVKIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVG-INGIQNYELVKSVTEFGLDIIET-----PEGDKWPQLI--VQQNLDREKRDTFVMKIKVEDGGNPPKSSTAILQVTISDVNDNRPIFQDSELEVSVPENAPTGTSVAQLHATDADWGSNAQIHFAFSNQISSSTKRHFAINSSTGLITVKQPLDREVTPVHKLIVLASDGGSTPSRATVIVNVTDVNDNVPAIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVPFRLKPVFND-----QFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNAPIFPQPEIQLSIPENNDPSTQLIKISATDADSGSNAEIIYTLGPDAPDGFHIDRRSGILSVGKRLDREKQERFSFIVIARDN----GSTP----LQSNVTVRLIVQDLNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDAD-AGDNAAITLSIL---------NGKDNFIIDPQTGVIKPNITFDREQQSSYTFMVKAIDGGQPPTSSYAKVTINVVDVNDNRPVFVIPSS-NYSYDLVRTTTTPGAVVTRVFAIDNDTGMNAELQYSIISSIIITSRVSPRGLFTIDKISGNITLQEKIVGADLGLHRLVVKVRDLGQPESLQAITLVHLFVNDTVSNATFIQEQLRKSMETPLDRNIGDSEVTPQANGYVIVVIAIIAGTMTV--ILVIFVTALVRCRQTPRH 849
BLAST of Protocadherin vs. Ensembl Medaka
Match: ENSORLT00000036025.1 (pep primary_assembly:ASM223467v1:10:15153493:15160535:-1 gene:ENSORLG00000023815.1 transcript:ENSORLT00000036025.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 222.246 bits (565), Expect = 1.122e-59 Identity = 199/676 (29.44%), Postives = 326/676 (48.22%), Query Frame = 3
Query: 267 LQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNF-VSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTD---STKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAH---------FSIDENTGVLRTNSIFDRE--KTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFS------IPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG--PITHRVSVDVVV 2225
+ F V E + G +IG+L ++ I L R ++ + F V L G LFV IDRE +C ++C LN+ ++ + N + I+++I DIND++P + + V N+ E S G RY LP A D D+ NS+ Y L S + FSI ++ D +L + +DREK + L+L A D G P +G+ + +N+ D+NDN+P+F KPL ++S++EN + + ++ A DLD N ++ +S N++ KFY+ ++G+I +K LDY +E N Y L +Q +D S + + +L++V + NDNAP ISI ++ V+E + T +A ++ TD D I+ L ++ T+ Y++++ LDRET + TI D G P +T +IN+QV D ND P FP VY+ E V + +TK+ A D D+ N+ L Y + ++ +I+ TG + FD E KT ++K++AT D LSS + V + D ND +P + E IP + +V + A D D N +SY + ++ + L+ + G I T + D + H + D+G ++ VS++VVV
Sbjct: 27 MSFSVSEEVDKGTVIGNLAKDLNIVSQQLEERGFRIVSLLSKKYFEVDLRTGALFVNERIDREELCPNTHKCS-LNIEGLISS---PMNIYRIEVNILDINDNAPKFLEQIHVFNVSESSSAGERYPLPAAHDADTGI-NSVKTYKL-----SPNEFFSIDVSTSRDGLSAELVLQKA---LDREKQPNVRLILTAVDGGKPARSGNMQIIVNVVDVNDNTPLFSKPLYKVSVRENESVGTTILKLNATDLDEGSNAEIKYSLMKRGNVDSHEKFYVVPESGEIVLKNRLDY-EENNAYELRVQASDKGGSPRSGYSKVLIEVVDMNDNAPEISITSVMSP------VKEKAEIGTVVALVTVTDKDGGQNGITTCKIKNILPF-KLTTNYK--NYYSLIVDGLLDRETVAEYNVTITAVDAGSLPLSSTAVINVQVSDVNDNAPTFPEGAMNVYVRENSQVGNVITKVTAHDADIDDNADLTYFLIDSNSWKTQISSILNINSKTGEIMAMQSFDYEKLKTFQFKVQAT----------DSGVPPLSSNVTVNVFVLDENDNSPSILAPYSEHGSVNSENIPYSAEAGYFVAKIRAVDPD-SGYNALLSYHL------SEPKGNNLFRIGTSSGEIRTKRRMSDND-LKSHPLLVLVSDNGEPSLSATVSIEVVV 661 HSP 2 Score: 136.732 bits (343), Expect = 2.621e-32 Identity = 177/674 (26.26%), Postives = 297/674 (44.07%), Query Frame = 3
Query: 888 HLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAET---ILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVY--IDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH-AHFSIDENTG---VLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSG--PITHRVSVDVVVKIEDLNDNFPQ----WSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPA--------ESRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRNLPGITYQSKEYRHGHPDGQSSPTAS----DMFSSAVKLSSDVPLY 2828
+ +NI DINDN+P FL+ + ++ E++ + A D D N T+ + +G + ++ +++ LD +++ N L+ + D K A + ++V V + NDN P+ S P S V EN T I L+ATD+D S S + V I+L LD E N ++ ++ D G P+ + I+V+D ND P +IT+V + E + + V + +D D G N +I + F + N L + + DRE EY + T D +L LSST +I V + D+ND AP F + + E S + V A D+DI+ N ++Y +I K+ IS + S G I +S D E F ++A DSG P++ V+V+V V D NDN P +S + S NI G V ++A+D DSG N+ L+Y + + + LF++ SG + ++ ND + L+V VSD+G L+ T + + + + E F + +L ++I +++V++ I +++++ L C+R + S HPDG S + + D+ S+ L SDV ++
Sbjct: 114 RIEVNILDINDNAPKFLEQIHVFNVSESSSAGERYPLPAAHDADTGINSVKTYKLSPNEFFSIDVSTSRDGLSAELVLQKALDREKQPNVRLI-LTAVDGGKPARSGNMQIIVNVVDVNDNTPLFS-KPLYKVS-----VRENESVGTTILKLNATDLDEGSNAEIKYSLMKRGNVDSHEKFYVVPESGEIVLKNRLDYEENNAYELRVQASDKGGSPRSGYSKVLIEVVDMNDNAPEI--SITSVMSPVKEKAEIGTVVALVTVTDKDGGQNGITTCKIKNILPFKLTTNYKNYYSLIVDGLLDRETVAEYNVTITAVDAGSLP--------LSSTAVINVQVSDVNDNAPTFPEGAMNVYVRENSQVGNVITKVTAHDADIDD-NADLTY-FLIDSNSWKTQISSILNINSKTGEIMAM-QSFDYEKLKTFQFKVQATDSGVPPLSSNVTVNVFVL--DENDNSPSILAPYSEHGSVN-SENIPYSAEAGYFVAKIRAVDPDSGYNALLSYHLSEPKGNNLFRIGTSSGEIRTKRRMSDNDLKSHPLLVLVSDNGEPSLSATVSIEVVVLESTADMQTPFRHVPLKEDSFSDLNLYLLIAIVSVSV----IFLLSLISLVAVRCHRTDGSFSRYSAPMITTHPDGSWSYSKATQQYDVCFSSDTLKSDVVVF 760
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000029673.1 (SMESG000029673.1) HSP 1 Score: 2080.06 bits (5388), Expect = 0.000e+0 Identity = 1054/1056 (99.81%), Postives = 1055/1056 (99.91%), Query Frame = 3
Query: 183 METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRNLPGITYQSKEYRHGHPDGQSSPTASDMFSSAVKLSSDVPLYHNQLYHPNRLIYEAPSGVMSFQTIRKPDSLPLYYTLKPKRSLSDGIGELPGNYMKTPFTNIYDIQQRHYALAQNFISVPPLTPENVNAHYFQHSNTVPTPTASTPMLNGSGISQANPNFESPTPLHGDIRLNNTVKWSDTVDDKRIYERITSAENAEIHCNHSLMTKDQISSFV 3350
METLANLSKFIIFLIVVDFPMKMAKSISLQF+VKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDREKIEKIELLLLAEDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNSSTIISCASSSGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPA ITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKALDSDSGLNSSLNYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRNLPGITYQSKEYRHGHPDGQSSPTASDMFSSAVKLSSDVPLYHNQLYHPNRLIYEAPSGVMSFQTIRKPDSLPLYYTLKPKRSLSDGIGELPGNYMKTPFTNIYDIQQRHYALAQNFISVPPLTPENVNAHYFQHSNTVPTPTASTPMLNGSGISQANPNFESPTPLHGDIRLNNTVKWSDTVDDKRIYERITSAENAEIHCNHSLMTKDQISSFV
Sbjct: 1 METLANLSKFIIFLIVVDFPMKMAKSISLQFRVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMKENNFVSLVNGKLFVKADIDRERICTKKNQCCCLNLFVIVYNLKIQSNYFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDREKIEKIELLLLAEDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNSSTIISCASSSGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPATITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDHAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKALDSDSGLNSSLNYEIIQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRFFEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYRNLPGITYQSKEYRHGHPDGQSSPTASDMFSSAVKLSSDVPLYHNQLYHPNRLIYEAPSGVMSFQTIRKPDSLPLYYTLKPKRSLSDGIGELPGNYMKTPFTNIYDIQQRHYALAQNFISVPPLTPENVNAHYFQHSNTVPTPTASTPMLNGSGISQANPNFESPTPLHGDIRLNNTVKWSDTVDDKRIYERITSAENAEIHCNHSLMTKDQISSFV 1056
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000012836.1 (SMESG000012836.1) HSP 1 Score: 300.827 bits (769), Expect = 1.106e-85 Identity = 262/824 (31.80%), Postives = 407/824 (49.39%), Query Frame = 3
Query: 306 LIGDLVENYRIQDFDLSRRENLN----FQMMKENN--FVSLVNGKLFVKADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQ--ISIEDINDHSPVWTQ--SKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKL-FSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPL-TEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGL-----KLSRVLTDLSVVT-----KYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNE-HELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRF--FEKDLVVMICMITVTLIVSGILVVAIVLLKC 2687
L+ + N + D + N N F+++ +N ++ GKL K+ IDRE IC + N C + LF++ + K + I+ I I DINDH+P W + + + + IPEHS I S + LP A DLD PDN YT+ + ++K ++ S + Y N+L L V +DREK + ++L+ A D G PPL+G + I +TDIND+SP F + IS+ EN I+ + A+D+D SD + L FSF ++ E F++ K+G++ +++ LDY+ ++ +Y +QVTD F + VKV N NDN+P IS+ + +L V EN + I ++ TD D++ GL + + + +LS ++ K+ + KP DRE + TIKC D G PP+ ++ + +LD ND P F I E + V + + +L A D D +N+ + + +F I+ TG + + IF+ E++ Y++ A V D KV + + I+D+ND +P F K Y FSI E DSDI IN+ I Y KP KS + + V+ DG+IF LDRE +F I A D+G T S + ++++D+NDN P+W H INIT VG V +A D D G NS L Y I + N ++F+L +GSLY+ + +D RL + V D G L T ++ ++ S F FE DL++++ ++ VTLI+ L+ AI LKC
Sbjct: 15 LVEECSNNSIVTDLNNRFHSNFNNDGHFRLLDQNKLFYIEEKFGKLRTKSRIDRESICKQVDANPDCKIALFILYHPGKRTTKPVMIKSIIHILDINDHAPTWNKVNNLMTLQIPEHSPINSAFRLPEAVDLDRGPDNVTKSYTISKNKDGEMKFDLRVIMKSSLNSKYGNELSLIVLGILDREKQSQYQVLITAMDGGVPPLSGELRVNIQVTDINDHSPRFKNQIPINISLHENTAINSIIFVFVAEDIDSSDANNLRFSFLSTTEDEVTQTFFLKEKSGELILQKSLDYETKM-SYTFTVQVTDGKHFTSIYVEVKVLNVNDNSPKISVQSF--AGGELLTVSENSESGQHIGAVVVTDADDN----------SGLLPVFCSIDKPIVELSPLSDEARNKFLLKTLKPFDREIGSYQIFTIKCSDTGEPPKHSSYTSRLHILDVNDNAPVFLNEPMRATIKENMAVGTLIYQLKAQDEDTELNANFRFYLQPDSEVNFRIESETGKIFSKIIFNAEESSRYEISAYVTDSL----EGTFHKVFGK---VDLNIEDMNDNSPRFDKDIYHFSIYEN-------------DSDISEINKAIRYNF--KPGTDKSILK--HIGVTQDGKIFVRSSQLDREKNSSFTFYIIAIDNGSPTLSSSAYIQIEVKDINDNSPEWIHPDPSLNHINITYHVPVGHEVIKFEAKDLDQGSNSELQYFITEPNSGRDIFQLEPTTGSLYVKRTLTVHDLRTHRLNILVKDRGNPSLERTLTFKVNIVQQIETYHGLSLFGKFEGDLLIILVLVIVTLIICLGLISAIWFLKC 801
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000012836.1 (SMESG000012836.1) HSP 1 Score: 300.827 bits (769), Expect = 1.123e-85 Identity = 261/819 (31.87%), Postives = 408/819 (49.82%), Query Frame = 3
Query: 306 LIGDLVENYRIQDFDLSRRENLN----FQMMKENN--FVSLVNGKLFVKADIDRERICTK--KNQCCCLNLFVIVYNLKIQSNYFEIQ--ISIEDINDHSPVWTQ--SKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVNNSQLKL-FSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPL-TEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISILPHVNSSNNVLLVEENIQDETAIASLSATDMDNXXXXXXXXXXXGGLKLSRVLTDLSVVT-----KYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPAAITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRID---HAHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKPYETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEIIQGNE-HELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYFHSEVSKLPAESRF--FEKDLVVMICMITVTLIVSGILVVAIVLLKC 2687
L+ + N + D + N N F+++ +N ++ GKL K+ IDRE IC + N C + LF++ + K + I+ I I DINDH+P W + + + + IPEHS I S + LP A DLD PDN YT+ + ++K ++ S + Y N+L L V +DREK + ++L+ A D G PPL+G + I +TDIND+SP F + IS+ EN I+ + A+D+D SD + L FSF ++ E F++ K+G++ +++ LDY+ ++ +Y +QVTD F + VKV N NDN+P IS+ + +L V EN + I ++ TD D++S ++ + + + +LS ++ K+ + KP DRE + TIKC D G PP+ ++ + +LD ND P F I E + V + + +L A D D +N+ + + +F I+ TG + + IF+ E++ Y++ A V D KV + + I+D+ND +P F K Y FSI E DSDI IN+ I Y KP KS + + V+ DG+IF LDRE +F I A D+G T S + ++++D+NDN P+W H INIT VG V +A D D G NS L Y I + N ++F+L +GSLY+ + +D RL + V D G L T ++ ++ S F FE DL++++ ++ VTLI+ L+ AI LKC
Sbjct: 7 LVEECSNNSIVTDLNNRFHSNFNNDGHFRLLDQNKLFYIEEKFGKLRTKSRIDRESICKQVDANPDCKIALFILYHPGKRTTKPVMIKSIIHILDINDHAPTWNKVNNLMTLQIPEHSPINSAFRLPEAVDLDRGPDNVTKSYTISKNKDGEMKFDLRVIMKSSLNSKYGNELSLIVLGILDREKQSQYQVLITAMDGGVPPLSGELRVNIQVTDINDHSPRFKNQIPINISLHENTAINSIIFVFVAEDIDSSDANNLRFSFLSTTEDEVTQTFFLKEKSGELILQKSLDYETKM-SYTFTVQVTDGKHFTSIYVEVKVLNVNDNSPKISVQSF--AGGELLTVSENSESGQHIGAVVVTDADDNSGLLPVF-----CSIDKPIVELSPLSDEARNKFLLKTLKPFDREIGSYQIFTIKCSDTGEPPKHSSYTSRLHILDVNDNAPVFLNEPMRATIKENMAVGTLIYQLKAQDEDTELNANFRFYLQPDSEVNFRIESETGKIFSKIIFNAEESSRYEISAYVTDSL----EGTFHKVFGK---VDLNIEDMNDNSPRFDKDIYHFSIYEN-------------DSDISEINKAIRYNF--KPGTDKSILK--HIGVTQDGKIFVRSSQLDREKNSSFTFYIIAIDNGSPTLSSSAYIQIEVKDINDNSPEWIHPDPSLNHINITYHVPVGHEVIKFEAKDLDQGSNSELQYFITEPNSGRDIFQLEPTTGSLYVKRTLTVHDLRTHRLNILVKDRGNPSLERTLTFKVNIVQQIETYHGLSLFGKFEGDLLIILVLVIVTLIICLGLISAIWFLKC 793
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000022791.1 (SMESG000022791.1) HSP 1 Score: 291.197 bits (744), Expect = 1.919e-81 Identity = 271/967 (28.02%), Postives = 436/967 (45.09%), Query Frame = 3
Query: 201 LSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMK-------ENNFVSLVNGKLFVKADIDRERICTKKNQ-----CCCLNLFV---IVYNLKIQSN-----YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVN-NSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISIL---------PHVNSSNNVLLVEENIQDETAIASLSATDMD-------NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPA------AITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH---AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKP-----------YETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI-------------------------IQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYF-------------HSEVSKLPAESRF-FEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYR-----NLPGITYQ----SKEYRHGHPDGQSSPTASDM 2786
L +F I+L F ++ I + F+V E S +IG+ I + L ++ + F E F+ + V +DRE IC + Q C F+ I+ + K Q++ + + I DIND+SP W+ I +++PEHSKIG+ LPLA D D P N+ +Y + Y + N KL + + +L L V+ + DREK + + L A D PL+G + I++TDIND P F K I EN + + Q+ AKD D SD KL F F NS++ R++FYIN G+I +DY+ + + Y +P+ VTD + L ++V+N NDN P IS+L P +S L EN +ASLS +D D N + + + + ++ + ++ TK DRE + A + C D T+ I + D ND P F I + I EGV + + + ++ A+D D+G N+ + Y +D FSID +G LR +FD EK +++L + N + ++L + I V I+D+NDC PVF+K Y F++ EG S +YVG V+ +D DI + + ++ P Y + + YF + G I LDRE SF I+A D + V ++I D+NDN P W + +N++ +E +G + LKA D D G N + Y I I+ N HE+F L+ +G++Y+ ++ +D ++ V+ SD G P I R++ + +K SR FE DL++MI ++ + ++V+ ++V+ I++L+C++ R L T Q S+ + PDG S +D+
Sbjct: 16 LIRFCIWLSYF-FNKEIHGQIEIHFKVVEESPTNSVIGN------IHNQALKQKGGVGFGDYYYKSITDIEPFFLDSKTYEFRVSKRVDREEICRFQMQNIMQNCRMTYKFIQSRIIGDEKGQTSDSSPEIIVVNVEIIDINDNSPKWSSPHIYLSLPEHSKIGTEITLPLAMDPDQPPTNTTQKYKISYQSVNDGFKL------KHSGRDHYEKLSLIVNKDFDREKQATVSVKLKAFDGDPNPLSGQLDINISLTDINDKQPHFKKTSIHKIINENIPLRSPILQLEAKDEDESDQHKLRFEFDNSVDETVRNRFYINPLTGEILTAGYIDYEIK-SEYTIPVIVTDGKHSDQATLTIEVKNVNDNNPEISVLYLSGSNFKTPGRSSQYRAYLA-ENKDPGFVVASLSVSDKDYESKRLGNQMNHLLDCRIDPHRESLELRSQSKLIDHFQLITTKMFDREETSQYFAQLICFDSDSNSLSTSVTFEISITDVNDNPPIFEVPFQGSRGIHSYSIKEGVAIGTTIVQVKATDRDIGNNAIIQYSLDSLSGTQFSIDPISGELRNIDVFDYEKMEKFEL---TINASNPIIERKNSQLLYTLQKITVNIEDVNDCPPVFEKDLYTFTVKEGPSKDVYVGKVVVKDDDISSKYNSNYFKIISNPHDIYDSSDSQMYTNSNSDASQYFRIGETGLIHVNVPVLDREKISSFSFKIQAADRSEKPLSSTAIVQIQILDVNDNPPLWVFPNTHNYEVNVSYQEAIGYCIANLKANDPDLGDNGKVTYRIVPSSFPFSFNTNEESKNLEVTESSDIKFNRHEMFDLDGSTGNIYIAQKMKLSDVGSKKIWVEASDQGTPP--QKKIERLHINIVNVDGNGHGSSQGQFNKRSGLSRVGFENDLMIMIVLVAIIILVAMVMVIIILMLRCRNTSRLMTSNKLNRDTCQSISASRSFLERRPDGHSCSPINDI 962
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000022791.1 (SMESG000022791.1) HSP 1 Score: 290.812 bits (743), Expect = 2.212e-81 Identity = 271/967 (28.02%), Postives = 436/967 (45.09%), Query Frame = 3
Query: 201 LSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYRIQDFDLSRRENLNFQMMK-------ENNFVSLVNGKLFVKADIDRERICTKKNQ-----CCCLNLFV---IVYNLKIQSN-----YFEIQISIEDINDHSPVWTQSKIVINIPEHSKIGSRYYLPLAKDLDSSPDNSISRYTLKYVN-NSQLKLFSIVYNSLPDKTYLNQLLLRVDANIDRXXXXXXXXXXXXXDSGSPPLTGSTHLTINITDINDNSPVFLKPLTEISIKENNFIDQYLCQMFAKDLDISDNDKLTFSFGNSMNIEDRSKFYINGKNGKIFVKQILDYDQEVNTYLLPIQVTDSTKFAETILLVKVQNENDNAPVISIL---------PHVNSSNNVLLVEENIQDETAIASLSATDMD-------NXXXXXXXXXXXGGLKLSRVLTDLSVVTKYTILLTKPLDRETNEFFQATIKCQDDGYPPQVTTKIINIQVLDKNDCTPHFPA------AITTVYIDEGVPVESFVTKLNASDCDVGVNSQLVYRIDH---AHFSIDENTGVLRTNSIFDREKTGEYKLEATVYDRRNLVDSDPTEKVLSSTTIIRVIIKDINDCAPVFKKLFYEFSIPEGSSPRMYVGSVLAEDSDIEAINRQISYAMVIKP-----------YETKSHISKLYFSVSPDGRIFTTKESLDRETYDMHSFSIEAWDSGPITHRVSVDVVVKIEDLNDNFPQWSHSSDLGLSINITREETVGRLVTVLKAXXXXXXXXXXXXYEI-------------------------IQGNEHELFKLNQKSGSLYLMKQPLSNDPEIIRLVVKVSDSGPSPLTNTTIVRIYF-------------HSEVSKLPAESRF-FEKDLVVMICMITVTLIVSGILVVAIVLLKCKHCYR-----NLPGITYQ----SKEYRHGHPDGQSSPTASDM 2786
L +F I+L F ++ I + F+V E S +IG+ I + L ++ + F E F+ + V +DRE IC + Q C F+ I+ + K Q++ + + I DIND+SP W+ I +++PEHSKIG+ LPLA D D P N+ +Y + Y + N KL + + +L L V+ + DREK + + L A D PL+G + I++TDIND P F K I EN + + Q+ AKD D SD KL F F NS++ R++FYIN G+I +DY+ + + Y +P+ VTD + L ++V+N NDN P IS+L P +S L EN +ASLS +D D N + + + + ++ + ++ TK DRE + A + C D T+ I + D ND P F I + I EGV + + + ++ A+D D+G N+ + Y +D FSID +G LR +FD EK +++L + N + ++L + I V I+D+NDC PVF+K Y F++ EG S +YVG V+ +D DI + + ++ P Y + + YF + G I LDRE SF I+A D + V ++I D+NDN P W + +N++ +E +G + LKA D D G N + Y I I+ N HE+F L+ +G++Y+ ++ +D ++ V+ SD G P I R++ + +K SR FE DL++MI ++ + ++V+ ++V+ I++L+C++ R L T Q S+ + PDG S +D+
Sbjct: 20 LIRFCIWLSYF-FNKEIHGQIEIHFKVVEESPTNSVIGN------IHNQALKQKGGVGFGDYYYKSITDIEPFFLDSKTYEFRVSKRVDREEICRFQMQNIMQNCRMTYKFIQSRIIGDEKGQTSDSSPEIIVVNVEIIDINDNSPKWSSPHIYLSLPEHSKIGTEITLPLAMDPDQPPTNTTQKYKISYQSVNDGFKL------KHSGRDHYEKLSLIVNKDFDREKQATVSVKLKAFDGDPNPLSGQLDINISLTDINDKQPHFKKTSIHKIINENIPLRSPILQLEAKDEDESDQHKLRFEFDNSVDETVRNRFYINPLTGEILTAGYIDYEIK-SEYTIPVIVTDGKHSDQATLTIEVKNVNDNNPEISVLYLSGSNFKTPGRSSQYRAYLA-ENKDPGFVVASLSVSDKDYESKRLGNQMNHLLDCRIDPHRESLELRSQSKLIDHFQLITTKMFDREETSQYFAQLICFDSDSNSLSTSVTFEISITDVNDNPPIFEVPFQGSRGIHSYSIKEGVAIGTTIVQVKATDRDIGNNAIIQYSLDSLSGTQFSIDPISGELRNIDVFDYEKMEKFEL---TINASNPIIERKNSQLLYTLQKITVNIEDVNDCPPVFEKDLYTFTVKEGPSKDVYVGKVVVKDDDISSKYNSNYFKIISNPHDIYDSSDSQMYTNSNSDASQYFRIGETGLIHVNVPVLDREKISSFSFKIQAADRSEKPLSSTAIVQIQILDVNDNPPLWVFPNTHNYEVNVSYQEAIGYCIANLKANDPDLGDNGKVTYRIVPSSFPFSFNTNEESKNLEVTESSDIKFNRHEMFDLDGSTGNIYIAQKMKLSDVGSKKIWVEASDQGTPP--QKKIERLHINIVNVDGNGHGSSQGQFNKRSGLSRVGFENDLMIMIVLVAIIILVAMVMVIIILMLRCRNTSRLMTSNKLNRDTCQSISASRSFLERRPDGHSCSPINDI 966 The following BLAST results are available for this feature:
BLAST of Protocadherin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015204 ID=SMED30015204|Name=Protocadherin|organism=Schmidtea mediterranea sexual|type=transcript|length=3429bpback to top protein sequence of SMED30015204-orf-1 >SMED30015204-orf-1 ID=SMED30015204-orf-1|Name=SMED30015204-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1057bp METLANLSKFIIFLIVVDFPMKMAKSISLQFQVKEHSEIGLLIGDLVENYback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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