Regulator of G-protein signaling 3

Overview
NameRegulator of G-protein signaling 3
Smed IDSMED30015176
Length (bp)2580
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Regulator of G-protein signaling 3 (SMED30015176) t-SNE clustered cells

Violin plots show distribution of expression levels for Regulator of G-protein signaling 3 (SMED30015176) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Regulator of G-protein signaling 3 (SMED30015176) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Regulator of G-protein signaling 3 (SMED30015176) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30015176

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
central nervous systemSMED30015176h1SMcG0022210 dd_Smed_v4_17732_0_1dd_Smed_v4PMID:27063937
Scimone et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30015176h1SMcG0022210 SmedASXL_007429SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30015176h1SMcG0022210 dd_Smed_v6_17732_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
photoreceptor neuronSMED30015176h1SMcG0022210 SMED30015176smed_20140614PMID:22884275
Lapan et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Human
Match: RGS3 (regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999])

HSP 1 Score: 112.849 bits (281), Expect = 1.102e-24
Identity = 72/280 (25.71%), Postives = 128/280 (45.71%), Query Frame = 1 
Query:  871 FPIKPEFTTLAPCK-----------GRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELES--LGCMSFGIKKFQI-KTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRP 1668
             P + E+T  +P +           G++ L+I  Q   + + + E   L S      +P+V+I L+   P    +    ++  P+   P F + F F +   D  KR++++ ++  +   +S  +GCMSFG+K       ++SGWYYLL E +G  KH K           +        ++    ++  G ++ ++ + +G  GFGFT+C  SPV V  VD    AE AG+   D +++++   V       +    R CP  + + +WR  PQ+   P
Sbjct:  114 LPRRDEWTQTSPARKRITHAKVQGAGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLI---PEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVA------RRRLRPLRDPLLRMPGGGDTENGKKL-KITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGP 383
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Human
Match: RGS3 (regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999])

HSP 1 Score: 112.849 bits (281), Expect = 1.102e-24
Identity = 72/280 (25.71%), Postives = 128/280 (45.71%), Query Frame = 1 
Query:  871 FPIKPEFTTLAPCK-----------GRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELES--LGCMSFGIKKFQI-KTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRP 1668
             P + E+T  +P +           G++ L+I  Q   + + + E   L S      +P+V+I L+   P    +    ++  P+   P F + F F +   D  KR++++ ++  +   +S  +GCMSFG+K       ++SGWYYLL E +G  KH K           +        ++    ++  G ++ ++ + +G  GFGFT+C  SPV V  VD    AE AG+   D +++++   V       +    R CP  + + +WR  PQ+   P
Sbjct:  114 LPRRDEWTQTSPARKRITHAKVQGAGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLI---PEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVA------RRRLRPLRDPLLRMPGGGDTENGKKL-KITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGP 383
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Human
Match: RGS3 (regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999])

HSP 1 Score: 110.923 bits (276), Expect = 1.828e-24
Identity = 68/255 (26.67%), Postives = 116/255 (45.49%), Query Frame = 1 
Query:  913 GRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELES--LGCMSFGIKKFQI-KTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRP 1668
            G++ L+I  Q   + + + E   L S      +P+V+I L+   P    +    ++  P+   P F + F F +   D  KR++++ ++  +   +S  +GCMSFG+K       ++SGWYYLL E +G  KH K     +         +       N          +++ + +G  GFGFT+C  SPV V  VD    AE AG+   D +++++   V       +    R CP  + + +WR  PQ+   P
Sbjct:   27 GQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLI---PEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVARRRLRPLRDPLLRMPGGGDTENGKK-------LKITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGP 271
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Human
Match: PRKCG (protein kinase C gamma [Source:HGNC Symbol;Acc:HGNC:9402])

HSP 1 Score: 62.3882 bits (150), Expect = 2.999e-9
Identity = 39/130 (30.00%), Postives = 74/130 (56.92%), Query Frame = 1 
Query:  910 KGRINLTILCQFS-RITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ L I    +  I + + EA NL  M+ N +S+P+V+++L+   P+ +N+    +       +PV++++F FN+ P D  +R+ +  +   + +  + +G MSFG+ +  +K  V GWY LL +E G
Sbjct:  158 RGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLI---PDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKLLNQEEG 283
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Human
Match: RGS3 (regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999])

HSP 1 Score: 57.7658 bits (138), Expect = 7.339e-8
Identity = 27/85 (31.76%), Postives = 43/85 (50.59%), Query Frame = 1 
Query: 1414 EVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRP 1668
            ++ + +G  GFGFT+C  SPV V  VD    AE AG+   D +++++   V       +    R CP  + + +WR  PQ+   P
Sbjct:   18 QITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGP 102
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0305069)

HSP 1 Score: 58.151 bits (139), Expect = 2.314e-8
Identity = 36/129 (27.91%), Postives = 76/129 (58.91%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI L I  + + +T+ +KE  NL  M+ N +S+P+V+++L   +P+ ++     +       +PV++++ ++++ P D  +RI+I  +   + +  + +G +SFGI +  IK   +GW+ LL ++ G
Sbjct:   23 RGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKL---IPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEI-IKNPTNGWFKLLTQDEG 147
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0112819)

HSP 1 Score: 58.151 bits (139), Expect = 2.839e-8
Identity = 36/129 (27.91%), Postives = 76/129 (58.91%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI L I  + + +T+ +KE  NL  M+ N +S+P+V+++L   +P+ ++     +       +PV++++ ++++ P D  +RI+I  +   + +  + +G +SFGI +  IK   +GW+ LL ++ G
Sbjct:  176 RGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKL---IPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEI-IKNPTNGWFKLLTQDEG 300
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0305070)

HSP 1 Score: 58.151 bits (139), Expect = 2.839e-8
Identity = 36/129 (27.91%), Postives = 76/129 (58.91%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI L I  + + +T+ +KE  NL  M+ N +S+P+V+++L   +P+ ++     +       +PV++++ ++++ P D  +RI+I  +   + +  + +G +SFGI +  IK   +GW+ LL ++ G
Sbjct:  176 RGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKL---IPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEI-IKNPTNGWFKLLTQDEG 300
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0331960)

HSP 1 Score: 58.151 bits (139), Expect = 2.970e-8
Identity = 36/129 (27.91%), Postives = 76/129 (58.91%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI L I  + + +T+ +KE  NL  M+ N +S+P+V+++L   +P+ ++     +       +PV++++ ++++ P D  +RI+I  +   + +  + +G +SFGI +  IK   +GW+ LL ++ G
Sbjct:  168 RGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKL---IPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEI-IKNPTNGWFKLLTQDEG 292
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Fly
Match: Pkc53E (gene:FBgn0003091 transcript:FBtr0087049)

HSP 1 Score: 58.151 bits (139), Expect = 2.970e-8
Identity = 36/129 (27.91%), Postives = 76/129 (58.91%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI L I  + + +T+ +KE  NL  M+ N +S+P+V+++L   +P+ ++     +       +PV++++ ++++ P D  +RI+I  +   + +  + +G +SFGI +  IK   +GW+ LL ++ G
Sbjct:  168 RGRIYLEINVKENLLTVQIKEGRNLIPMDPNGLSDPYVKVKL---IPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPEDKDRRILIEVWDWDRTSRNDFMGALSFGISEI-IKNPTNGWFKLLTQDEG 292
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Zebrafish
Match: rgs3b (regulator of G protein signaling 3b [Source:ZFIN;Acc:ZDB-GENE-060531-24])

HSP 1 Score: 90.1225 bits (222), Expect = 5.068e-18
Identity = 63/236 (26.69%), Postives = 113/236 (47.88%), Query Frame = 1 
Query:  952 ITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELES--LGCMSFGIKKFQIKT-QVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPP 1650
            +T+L  EA  L        + +V+I +  ++ + +    + +    +  SPVF++ F  ++   D  KR++++ ++   +   S  LGCMSFG+      + ++ GWYYLL EE+G  KH K     + +T + + +     + +   N     Q   V +++G  GFGFT+C  SPV V  VD    A  AG+   D +++++   V       +    R C   + V +WR+ P
Sbjct:    4 LTVL--EARGLMGREYRPCDSYVKISIAPDVDHSKR---WKTRTVLDCKSPVFNEGFMLDVDEDDQKKRLLVTVWNRDRDSRRSDFLGCMSFGVHSLITSSKEIRGWYYLLGEELGRSKHLKVASRRIRQTAAAAPNYEAGPESSGPEN----MQSFTVTILRGKDGFGFTICSDSPVRVQAVDPGGPAHQAGLQQLDTLLQLNGQPVEHWKCVDLAHAIRNCRNEITVVVWRTVP 230
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Zebrafish
Match: arhgef11 (Rho guanine nucleotide exchange factor (GEF) 11 [Source:ZFIN;Acc:ZDB-GENE-070604-1])

HSP 1 Score: 58.9214 bits (141), Expect = 1.722e-8
Identity = 40/121 (33.06%), Postives = 64/121 (52.89%), Query Frame = 1 
Query: 1360 QDSKLTNLTNSNVGYQIIE--VKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPAVPFN-MHNSKTYP 1713
            Q   L +L++ N G  +++  V + +   GFGFT+CG     V +V    +A  AG+  GD IIK++   VS  S + VV+M +     V +TL   PP ++  PL  +P + + N +T P
Sbjct:   30 QRETLPDLSSDNTGTGLVQRCVVVQRDNLGFGFTVCGERIKLVQNVRPGGAAVKAGVQEGDRIIKVNGSMVSSMSHQEVVKMIKSG-TYVALTLQGPPPSVASTPLQPLPSDLLSNHRTAP 149
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Zebrafish
Match: prkcab (protein kinase C, alpha, b [Source:ZFIN;Acc:ZDB-GENE-131121-412])

HSP 1 Score: 58.9214 bits (141), Expect = 1.927e-8
Identity = 38/129 (29.46%), Postives = 72/129 (55.81%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI + I     R+ + + EA NL  M+ N +S+P+V+++L+   P+ +N     +    ++ +P +++SF F +   D  +R+ +  +   +    + +G MSFG+ +  IK  VSGWY +L +E G
Sbjct:  111 RGRIFMKIEVSGDRLHVTVGEARNLIPMDPNGLSDPYVKLKLI---PDPKNETKQKTRTIRSSLNPTWNESFIFKLKASDKERRLSVEVWDWDRTTRNDFMGSMSFGVSEL-IKAPVSGWYKMLNQEEG 235
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Zebrafish
Match: prkcaa (protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GENE-050208-100])

HSP 1 Score: 58.9214 bits (141), Expect = 2.147e-8
Identity = 33/129 (25.58%), Postives = 74/129 (57.36%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ + I     ++ + + E  NL  M+ N +S+P+V+++L+   P+ +N     ++   ++ +P ++++F+F + P D  +R+ +  +   +    + +G MSFG+ +  +K+ V GWY +L +E G
Sbjct:  157 RGRLYMKIEVIGDKMHVTVGEGKNLIPMDPNGLSDPYVKLKLI---PDPKNETKQKTKTIRSSLNPTWNETFTFKLKPADKDRRLAVEVWDWDRTTRNDFMGSMSFGVSEL-MKSPVCGWYKMLNQEEG 281
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Zebrafish
Match: prkcab (protein kinase C, alpha, b [Source:ZFIN;Acc:ZDB-GENE-131121-412])

HSP 1 Score: 58.9214 bits (141), Expect = 2.194e-8
Identity = 38/129 (29.46%), Postives = 72/129 (55.81%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI + I     R+ + + EA NL  M+ N +S+P+V+++L+   P+ +N     +    ++ +P +++SF F +   D  +R+ +  +   +    + +G MSFG+ +  IK  VSGWY +L +E G
Sbjct:  111 RGRIFMKIEVSGDRLHVTVGEARNLIPMDPNGLSDPYVKLKLI---PDPKNETKQKTRTIRSSLNPTWNESFIFKLKASDKERRLSVEVWDWDRTTRNDFMGSMSFGVSEL-IKAPVSGWYKMLNQEEG 235
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Xenopus
Match: RGS12 (regulator of G-protein signaling 12 [Source:NCBI gene;Acc:779463])

HSP 1 Score: 60.8474 bits (146), Expect = 9.705e-9
Identity = 28/72 (38.89%), Postives = 42/72 (58.33%), Query Frame = 1 
Query: 1396 VGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMC 1611
            V  ++  V++ +G  G+GFTL G SP  +S V  +S AE  G+ PGD I  ++  NV  +S E VV++   C
Sbjct:   16 VSSRLRSVEVARGRTGYGFTLSGQSPCVISSVIKESPAEFVGLKPGDQICAVNEINVKNASHEDVVKLIGKC 87
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Xenopus
Match: RGS12 (regulator of G-protein signaling 12 [Source:NCBI gene;Acc:779463])

HSP 1 Score: 60.8474 bits (146), Expect = 1.036e-8
Identity = 28/72 (38.89%), Postives = 42/72 (58.33%), Query Frame = 1 
Query: 1396 VGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMC 1611
            V  ++  V++ +G  G+GFTL G SP  +S V  +S AE  G+ PGD I  ++  NV  +S E VV++   C
Sbjct:   16 VSSRLRSVEVARGRTGYGFTLSGQSPCVISSVIKESPAEFVGLKPGDQICAVNEINVKNASHEDVVKLIGKC 87
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Xenopus
Match: RGS12 (regulator of G-protein signaling 12 [Source:NCBI gene;Acc:779463])

HSP 1 Score: 60.8474 bits (146), Expect = 1.051e-8
Identity = 28/72 (38.89%), Postives = 42/72 (58.33%), Query Frame = 1 
Query: 1396 VGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMC 1611
            V  ++  V++ +G  G+GFTL G SP  +S V  +S AE  G+ PGD I  ++  NV  +S E VV++   C
Sbjct:   16 VSSRLRSVEVARGRTGYGFTLSGQSPCVISSVIKESPAEFVGLKPGDQICAVNEINVKNASHEDVVKLIGKC 87
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Xenopus
Match: rai2 (retinoic acid induced 2 [Source:Xenbase;Acc:XB-GENE-965588])

HSP 1 Score: 52.7582 bits (125), Expect = 3.483e-6
Identity = 30/86 (34.88%), Postives = 46/86 (53.49%), Query Frame = 1 
Query: 1441 GFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPAVPFNMHN 1698
            GFG T+ G +PV+V  V  D +A  AG+  GD IIK++   V+ S+   VV++ +     V +T+   PP     PL     ++HN
Sbjct:   55 GFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHIEVVKLIK-SGSYVALTVQGRPPGSPTIPLTDSEADVHN 139
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Xenopus
Match: rai2 (retinoic acid induced 2 [Source:Xenbase;Acc:XB-GENE-965588])

HSP 1 Score: 52.373 bits (124), Expect = 3.572e-6
Identity = 30/86 (34.88%), Postives = 46/86 (53.49%), Query Frame = 1 
Query: 1441 GFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPAVPFNMHN 1698
            GFG T+ G +PV+V  V  D +A  AG+  GD IIK++   V+ S+   VV++ +     V +T+   PP     PL     ++HN
Sbjct:   76 GFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHIEVVKLIK-SGSYVALTVQGRPPGSPTIPLTDSEADVHN 160
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Mouse
Match: Rgs3 (regulator of G-protein signaling 3 [Source:MGI Symbol;Acc:MGI:1354734])

HSP 1 Score: 114.775 bits (286), Expect = 6.576e-26
Identity = 68/259 (26.25%), Postives = 121/259 (46.72%), Query Frame = 1 
Query:  913 GRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELES--LGCMSFGIKKFQI-KTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVG----YQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRP 1668
            G++ L+I  Q   + + + E   L S    + +P+V++ L+   P    +P   +++ P+   P F + F F +      KR++++ ++  +   +   +GCMSFG++       ++SGWYYLL E++G  KH K                LQ  +   L     G     + +++ + +G  GFGFT+C  SPV V  VD    AE AG+   D +++++   V       +    R CP  + + +WR  PQ+   P
Sbjct:   35 GQLKLSIDAQDRVLLLHIIEGKGLMSREPGICDPYVKVSLI---PEDSQLPCQTTQIIPDCRDPAFHEHFFFPVPEEGDQKRLLVTVWNRASETRQHTLIGCMSFGVRSLLTPDKEISGWYYLLGEDLGRTKHLKVA-----------RRRLQPLRDMLLRMPGEGDPENGEKLQITIRRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRVVPQIKPGP 279
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Mouse
Match: Rgs3 (regulator of G-protein signaling 3 [Source:MGI Symbol;Acc:MGI:1354734])

HSP 1 Score: 114.39 bits (285), Expect = 9.392e-26
Identity = 68/259 (26.25%), Postives = 121/259 (46.72%), Query Frame = 1 
Query:  913 GRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYH--VQNNELESLGCMSFGIKKFQI-KTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVG----YQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRP 1668
            G++ L+I  Q   + + + E   L S    + +P+V++ L+   P    +P   +++ P+   P F + F F +      KR++++ ++   +  +   +GCMSFG++       ++SGWYYLL E++G  KH K                LQ  +   L     G     + +++ + +G  GFGFT+C  SPV V  VD    AE AG+   D +++++   V       +    R CP  + + +WR  PQ+   P
Sbjct:   27 GQLKLSIDAQDRVLLLHIIEGKGLMSREPGICDPYVKVSLI---PEDSQLPCQTTQIIPDCRDPAFHEHFFFPVPEEGDQKRLLVTVWNRASETRQHTLIGCMSFGVRSLLTPDKEISGWYYLLGEDLGRTKHLKVA-----------RRRLQPLRDMLLRMPGEGDPENGEKLQITIRRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRVVPQIKPGP 271
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Mouse
Match: Prkcg (Protein kinase C gamma type [Source:UniProtKB/Swiss-Prot;Acc:P63318])

HSP 1 Score: 63.929 bits (154), Expect = 6.230e-10
Identity = 41/130 (31.54%), Postives = 75/130 (57.69%), Query Frame = 1 
Query:  910 KGRINLTILCQFS-RITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ L I    S  I I + EA NL  M+ N +S+P+V+++L+   P+ +N+    ++      +PV++++F FN+ P D  +R+ +  +   + +  + +G MSFG+ +  +K  V GWY LL +E G
Sbjct:  158 RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLI---PDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKLLNQEEG 283
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Mouse
Match: Prkcg (Protein kinase C gamma type [Source:UniProtKB/Swiss-Prot;Acc:P63318])

HSP 1 Score: 63.929 bits (154), Expect = 6.230e-10
Identity = 41/130 (31.54%), Postives = 75/130 (57.69%), Query Frame = 1 
Query:  910 KGRINLTILCQFS-RITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ L I    S  I I + EA NL  M+ N +S+P+V+++L+   P+ +N+    ++      +PV++++F FN+ P D  +R+ +  +   + +  + +G MSFG+ +  +K  V GWY LL +E G
Sbjct:  158 RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLI---PDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKLLNQEEG 283
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Mouse
Match: Prkcg (protein kinase C, gamma [Source:MGI Symbol;Acc:MGI:97597])

HSP 1 Score: 63.929 bits (154), Expect = 6.230e-10
Identity = 41/130 (31.54%), Postives = 75/130 (57.69%), Query Frame = 1 
Query:  910 KGRINLTILCQFS-RITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ L I    S  I I + EA NL  M+ N +S+P+V+++L+   P+ +N+    ++      +PV++++F FN+ P D  +R+ +  +   + +  + +G MSFG+ +  +K  V GWY LL +E G
Sbjct:  158 RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLI---PDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKLLNQEEG 283
[Close]
BLAST of Regulator of G-protein signaling 3 vs. UniProt/SwissProt
Match: sp|P49796|RGS3_HUMAN (Regulator of G-protein signaling 3 OS=Homo sapiens OX=9606 GN=RGS3 PE=1 SV=2)

HSP 1 Score: 112.849 bits (281), Expect = 5.293e-24
Identity = 72/280 (25.71%), Postives = 128/280 (45.71%), Query Frame = 1 
Query:  871 FPIKPEFTTLAPCK-----------GRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELES--LGCMSFGIKKFQI-KTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRP 1668
             P + E+T  +P +           G++ L+I  Q   + + + E   L S      +P+V+I L+   P    +    ++  P+   P F + F F +   D  KR++++ ++  +   +S  +GCMSFG+K       ++SGWYYLL E +G  KH K           +        ++    ++  G ++ ++ + +G  GFGFT+C  SPV V  VD    AE AG+   D +++++   V       +    R CP  + + +WR  PQ+   P
Sbjct:  114 LPRRDEWTQTSPARKRITHAKVQGAGQLRLSIDAQDRVLLLHIIEGKGLISKQPGTCDPYVKISLI---PEDSRLRHQKTQTVPDCRDPAFHEHFFFPVQEEDDQKRLLVTVWNRASQSRQSGLIGCMSFGVKSLLTPDKEISGWYYLLGEHLGRTKHLKVA------RRRLRPLRDPLLRMPGGGDTENGKKL-KITIPRGKDGFGFTICCDSPVRVQAVDSGGPAERAGLQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPGP 383
[Close]
BLAST of Regulator of G-protein signaling 3 vs. UniProt/SwissProt
Match: sp|P63319|KPCG_RAT (Protein kinase C gamma type OS=Rattus norvegicus OX=10116 GN=Prkcg PE=1 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 4.727e-9
Identity = 41/130 (31.54%), Postives = 75/130 (57.69%), Query Frame = 1 
Query:  910 KGRINLTILCQFS-RITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ L I    S  I I + EA NL  M+ N +S+P+V+++L+   P+ +N+    ++      +PV++++F FN+ P D  +R+ +  +   + +  + +G MSFG+ +  +K  V GWY LL +E G
Sbjct:  158 RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLI---PDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKLLNQEEG 283
[Close]
BLAST of Regulator of G-protein signaling 3 vs. UniProt/SwissProt
Match: sp|P63318|KPCG_MOUSE (Protein kinase C gamma type OS=Mus musculus OX=10090 GN=Prkcg PE=1 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 4.727e-9
Identity = 41/130 (31.54%), Postives = 75/130 (57.69%), Query Frame = 1 
Query:  910 KGRINLTILCQFS-RITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ L I    S  I I + EA NL  M+ N +S+P+V+++L+   P+ +N+    ++      +PV++++F FN+ P D  +R+ +  +   + +  + +G MSFG+ +  +K  V GWY LL +E G
Sbjct:  158 RGRLQLEIRAPTSDEIHITVGEARNLIPMDPNGLSDPYVKLKLI---PDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKLLNQEEG 283
[Close]
BLAST of Regulator of G-protein signaling 3 vs. UniProt/SwissProt
Match: sp|P05128|KPCG_BOVIN (Protein kinase C gamma type (Fragment) OS=Bos taurus OX=9913 GN=PRKCG PE=2 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 8.149e-9
Identity = 40/130 (30.77%), Postives = 74/130 (56.92%), Query Frame = 1 
Query:  910 KGRINLTILCQFS-RITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ L I    S  I + + EA NL  M+ N +S+P+V+++L+   P+ +N+    +       +PV++++F FN+ P D  +R+ +  +   + +  + +G MSFG+ +  +K  V GWY LL +E G
Sbjct:  143 RGRLQLEIRAPTSDEIHVTVGEARNLIPMDPNGLSDPYVKLKLI---PDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKLLNQEEG 268
[Close]
BLAST of Regulator of G-protein signaling 3 vs. UniProt/SwissProt
Match: sp|Q4R4U2|KPCG_MACFA (Protein kinase C gamma type OS=Macaca fascicularis OX=9541 GN=PRKCG PE=2 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 1.014e-8
Identity = 40/130 (30.77%), Postives = 74/130 (56.92%), Query Frame = 1 
Query:  910 KGRINLTILCQFS-RITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GR+ L I    +  I I + EA NL  M+ N +S+P+V+++L+   P+ +N+    +       +PV++++F FN+ P D  +R+ +  +   + +  + +G MSFG+ +  +K  V GWY LL +E G
Sbjct:  158 RGRLQLEIRAPTADEIHITVGEARNLIPMDPNGLSDPYVKLKLI---PDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDFMGAMSFGVSEL-LKAPVDGWYKLLNQEEG 283
[Close]
BLAST of Regulator of G-protein signaling 3 vs. TrEMBL
Match: A0A1S3IK27 (regulator of G-protein signaling 3-like OS=Lingula unguis OX=7574 GN=LOC106164761 PE=4 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 6.545e-33
Identity = 83/247 (33.60%), Postives = 137/247 (55.47%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELESLGCMSFGIKKF-QIKTQVSGWYYLLKEEIGYRKHWK--AGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWR 1641
            KG++ L++      +TI + +A NL  + N + N ++++ L+   P+ +      +++    ++P +D+ FSF I P D  KR+++S +H +  E E LGCMSFGIKK  + K ++ GWY+LL EEIG +KH K   G   V               +  + +  +  + + V L +G RGFGFT+ G  PV V  V+  S A  +G+  GD I++I++ NVS+S+ E+VVR+ R     + V + R
Sbjct:   34 KGKVKLSVYMNCGLLTIHVVQAKNLFMVGNKLCNSYLKLCLV---PDEKKRTQCKTKIIRGTNNPKYDQRFSFEILPEDQDKRLILSVWHRRKTESELLGCMSFGIKKLVKSKKEIGGWYFLLSEEIGRQKHLKFTPGICKVQTKAY--------QHIPKVHSDVLWMESLTVCLRRGERGFGFTVVGSCPVRVGRVEQSSEAWSSGLRTGDYIVQINSQNVSRSTAESVVRLVRHSSNQIIVDVQR 269
[Close]
BLAST of Regulator of G-protein signaling 3 vs. TrEMBL
Match: A0A183APU1 (PDZ domain-containing protein OS=Echinostoma caproni OX=27848 PE=4 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 9.267e-33
Identity = 65/128 (50.78%), Postives = 91/128 (71.09%), Query Frame = 1 
Query: 2086 IINRLQYQGHLKKVDFSQMSPNLEIYGPASLKEGNCLFPVHIYLFSQVLLVGQLEPDGHITVIKEPIYCSKICYANIPAFCYDEIILQYINEVGRKQFIYFQATNIKEWLNRIQRHMIYHCNWWMPNI 2469
            I++ L+Y  H+K+VDF Q SP LE YG  +L E NC   V + +F+ +LL+ Q  P+  +TVIK+PIY +KICY NIP    D++ILQYI++  RKQ ++FQ +N++EWL  IQ HM+Y+ NWWM NI
Sbjct:  481 IVDCLKYVSHVKQVDFRQHSPRLEHYGCLNLLESNCCSKVELLMFTDLLLIAQRAPNHFLTVIKDPIYNTKICYVNIPPNASDQLILQYIDDHNRKQIVHFQGSNVREWLAWIQGHMVYNGNWWMSNI 608

HSP 2 Score: 89.7373 bits (221), Expect = 1.328e-14
Identity = 40/73 (54.79%), Postives = 55/73 (75.34%), Query Frame = 1 
Query: 1423 LVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWR 1641
            L +G +GFGFTL GG PVYVSHV+ +S A  AG+ PGD I+ +D+ NVS+S+T++VVR+FRM    V +T+ R
Sbjct:  165 LARGPKGFGFTLSGGCPVYVSHVEPNSPALQAGVQPGDFIVAVDSINVSRSTTDSVVRIFRMAQNPVYLTVCR 237
[Close]
BLAST of Regulator of G-protein signaling 3 vs. TrEMBL
Match: A0A3P8HKZ6 (PDZ domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS8976 PE=4 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 9.437e-33
Identity = 65/128 (50.78%), Postives = 91/128 (71.09%), Query Frame = 1 
Query: 2086 IINRLQYQGHLKKVDFSQMSPNLEIYGPASLKEGNCLFPVHIYLFSQVLLVGQLEPDGHITVIKEPIYCSKICYANIPAFCYDEIILQYINEVGRKQFIYFQATNIKEWLNRIQRHMIYHCNWWMPNI 2469
            I++ L+Y  H+K+VDF Q SP LE YG  +L E NC   V + +F+ +LL+ Q  P+  +TVIK+PIY +KICY NIP    D++ILQYI++  RKQ ++FQ +N++EWL  IQ HM+Y+ NWWM NI
Sbjct:  481 IVDCLKYVSHVKQVDFRQHSPRLEHYGCLNLLESNCCSKVELLMFTDLLLIAQRAPNHFLTVIKDPIYNTKICYVNIPPNASDQLILQYIDDHNRKQIVHFQGSNVREWLAWIQGHMVYNGNWWMSNI 608

HSP 2 Score: 89.7373 bits (221), Expect = 1.282e-14
Identity = 40/73 (54.79%), Postives = 55/73 (75.34%), Query Frame = 1 
Query: 1423 LVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWR 1641
            L +G +GFGFTL GG PVYVSHV+ +S A  AG+ PGD I+ +D+ NVS+S+T++VVR+FRM    V +T+ R
Sbjct:  165 LARGPKGFGFTLSGGCPVYVSHVEPNSPALQAGVQPGDFIVAVDSINVSRSTTDSVVRIFRMAQNPVYLTVCR 237
[Close]
BLAST of Regulator of G-protein signaling 3 vs. TrEMBL
Match: A0A504XP41 (Delphilin OS=Fasciola gigantica OX=46835 GN=FGIG_11944 PE=4 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 5.360e-30
Identity = 68/128 (53.12%), Postives = 92/128 (71.88%), Query Frame = 1 
Query: 2086 IINRLQYQGHLKKVDFSQMSPNLEIYGPASLKEGNCLFPVHIYLFSQVLLVGQLEPDGHITVIKEPIYCSKICYANIPAFCYDEIILQYINEVGRKQFIYFQATNIKEWLNRIQRHMIYHCNWWMPNI 2469
            I++ L+Y GH+K+VDF Q SP LE YG  +L E NC   V + LFS +LL+ Q  P+   TVIK+PIY +KICY NIP+   D++ILQYI++  RKQ ++FQ +N++EWL  IQ HM+Y+ NWWM NI
Sbjct:  477 IVDCLKYVGHVKQVDFRQHSPRLEHYGCLNLLESNCCSKVELLLFSDLLLIAQRAPNHFFTVIKDPIYNTKICYVNIPSNASDQLILQYIDDHNRKQIVHFQGSNVREWLAWIQGHMVYNSNWWMENI 604

HSP 2 Score: 89.7373 bits (221), Expect = 1.358e-14
Identity = 40/73 (54.79%), Postives = 55/73 (75.34%), Query Frame = 1 
Query: 1423 LVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWR 1641
            L +G +GFGFTL GG PVYVSHV+ +S A  AG+ PGD I+ +DN NVS+S+T++VVR+FR+    V +T+ R
Sbjct:  169 LTRGPKGFGFTLSGGCPVYVSHVEPNSPAMQAGVQPGDFIVAVDNSNVSRSTTDSVVRIFRIAQNPVHLTICR 241
[Close]
BLAST of Regulator of G-protein signaling 3 vs. TrEMBL
Match: A0A4E0S436 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_000622 PE=4 SV=1)

HSP 1 Score: 139.813 bits (351), Expect = 5.474e-30
Identity = 68/128 (53.12%), Postives = 92/128 (71.88%), Query Frame = 1 
Query: 2086 IINRLQYQGHLKKVDFSQMSPNLEIYGPASLKEGNCLFPVHIYLFSQVLLVGQLEPDGHITVIKEPIYCSKICYANIPAFCYDEIILQYINEVGRKQFIYFQATNIKEWLNRIQRHMIYHCNWWMPNI 2469
            I++ L+Y GH+K+VDF Q SP LE YG  +L E NC   V + LFS +LL+ Q  P+   TVIK+PIY +KICY NIP+   D++ILQYI++  RKQ ++FQ +N++EWL  IQ HM+Y+ NWWM NI
Sbjct: 1043 IVDCLKYVGHVKQVDFRQHSPRLEHYGCLNLLESNCCSKVELLLFSDLLLIAQRAPNHFFTVIKDPIYNTKICYVNIPSNASDQLILQYIDDHNRKQIVHFQGSNVREWLAWIQGHMVYNSNWWMENI 1170

HSP 2 Score: 99.3673 bits (246), Expect = 2.223e-17
Identity = 50/148 (33.78%), Postives = 88/148 (59.46%), Query Frame = 1 
Query:  877 IKPEFTTLAPCKGRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQ--NNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIGYRKHWKAG 1314
            ++   + LAPCKG+++L I      I +L+ EA  LRS  ++  N FV++ ++   P+  NI    +++  + ++PV++KS S +++   + +RI+++ Y  Q  N E E +G MSFG+     K  ++GWYYLL E +  +KH +AG
Sbjct:  456 LRSPISVLAPCKGKLHLKIESNNGVIQLLIIEAKGLRSCTDAPCNSFVKVTVV---PDRNNIFTQTTQIVESKANPVYNKSISLDLNKSKHARRILLTVYCQQTLNGENELIGGMSFGVTGITTKKAIAGWYYLLNETMARKKHLRAG 600

HSP 3 Score: 90.1225 bits (222), Expect = 1.576e-14
Identity = 40/73 (54.79%), Postives = 55/73 (75.34%), Query Frame = 1 
Query: 1423 LVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWR 1641
            L +G +GFGFTL GG PVYVSHV+ +S A  AG+ PGD I+ +DN NVS+S+T++VVR+FR+    V +T+ R
Sbjct:  735 LTRGPKGFGFTLSGGCPVYVSHVEPNSPAMQAGVQPGDFIVAVDNSNVSRSTTDSVVRIFRIAQNPVHLTICR 807
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Cavefish
Match: rgs3b (regulator of G-protein signaling 3 [Source:NCBI gene;Acc:103021936])

HSP 1 Score: 93.9745 bits (232), Expect = 4.384e-19
Identity = 63/259 (24.32%), Postives = 121/259 (46.72%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQ--NNELESLGCMSFGIKKF-QIKTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVG---------YQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPP 1650
            KG++ L +      + + + EA  L        + +V+I L+  + + +      +    +  +PVF+++F+ ++   + +KR++++ ++    +  ++ LGCMSFG++       ++ GWYYLL EE+G  KH +             +  ++ S    L+N   G          Q + V +++G  GFGFT+C  SPV V  VD    A  AG+   D +++++   V       +    R C   + V +WR+ P
Sbjct:  138 KGQLKLIVTPYNRLLCVQILEARGLLGKEYRPCDSYVKISLVPEVDHSKRQ---RTRTVLDCKNPVFNETFAISVGEEELHKRLLVTAWNRSRTSRRIDFLGCMSFGVQSLISSAKEIRGWYYLLGEELGRSKHLRVA-----------SRRIKQSAEAALSNHAAGPEFAAQPENTQSLTVTILRGKDGFGFTICSDSPVRVQAVDPGGPAHQAGLQQLDTLLQLNGQPVEHWKCVDLAHAIRNCRNEITVVVWRTMP 382
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Cavefish
Match: rgs3b (regulator of G-protein signaling 3 [Source:NCBI gene;Acc:103021936])

HSP 1 Score: 92.0485 bits (227), Expect = 1.621e-18
Identity = 62/258 (24.03%), Postives = 120/258 (46.51%), Query Frame = 1 
Query:  913 GRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQ--NNELESLGCMSFGIKKF-QIKTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVG---------YQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPP 1650
            G++ L +      + + + EA  L        + +V+I L+  + + +      +    +  +PVF+++F+ ++   + +KR++++ ++    +  ++ LGCMSFG++       ++ GWYYLL EE+G  KH +             +  ++ S    L+N   G          Q + V +++G  GFGFT+C  SPV V  VD    A  AG+   D +++++   V       +    R C   + V +WR+ P
Sbjct:   29 GQLKLIVTPYNRLLCVQILEARGLLGKEYRPCDSYVKISLVPEVDHSKRQ---RTRTVLDCKNPVFNETFAISVGEEELHKRLLVTAWNRSRTSRRIDFLGCMSFGVQSLISSAKEIRGWYYLLGEELGRSKHLRVA-----------SRRIKQSAEAALSNHAAGPEFAAQPENTQSLTVTILRGKDGFGFTICSDSPVRVQAVDPGGPAHQAGLQQLDTLLQLNGQPVEHWKCVDLAHAIRNCRNEITVVVWRTMP 272
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Cavefish
Match: prkcbb (protein kinase C beta type [Source:NCBI gene;Acc:103025973])

HSP 1 Score: 58.9214 bits (141), Expect = 1.613e-8
Identity = 37/129 (28.68%), Postives = 75/129 (58.14%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQ-NNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI +T   + + +T+ +KEA NL  M+ N +S+P+V+++L   +P+ ++     ++      +P ++++F+FN+   D  +R+ +  +     +  + +G +SFGI + Q K  V GW+ LL +E G
Sbjct:  157 RGRIQITADIKNNALTVSIKEAKNLVPMDPNGLSDPYVKLKL---IPDPKSESKQKTKTIKCCLNPTWNETFTFNLKDADKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQ-KQGVDGWFKLLSQEEG 281
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Cavefish
Match: prkcbb (protein kinase C beta type [Source:NCBI gene;Acc:103025973])

HSP 1 Score: 58.5362 bits (140), Expect = 2.440e-8
Identity = 37/129 (28.68%), Postives = 75/129 (58.14%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQ-NNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI +T   + + +T+ +KEA NL  M+ N +S+P+V+++L   +P+ ++     ++      +P ++++F+FN+   D  +R+ +  +     +  + +G +SFGI + Q K  V GW+ LL +E G
Sbjct:  157 RGRIQITADIKNNALTVSIKEAKNLVPMDPNGLSDPYVKLKL---IPDPKSESKQKTKTIKCCLNPTWNETFTFNLKDADKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQ-KQGVDGWFKLLSQEEG 281
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Cavefish
Match: ENSAMXT00000048876.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001095.1:37852:40661:-1 gene:ENSAMXG00000031732.1 transcript:ENSAMXT00000048876.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 1.125e-7
Identity = 27/66 (40.91%), Postives = 39/66 (59.09%), Query Frame = 1 
Query: 1444 FGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRM---FRMCPKSVKVT 1632
            FGF L G  P Y+  V   SSA +AG+ PGD +++ID  NVS  ST+A++ +    +  P S+ V 
Sbjct:   38 FGFKLGGDGPSYILSVVEGSSAYMAGLQPGDQVLEIDGQNVSSLSTKALIALAQTLKTVPPSIGVV 103
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Sea Lamprey
Match: ARHGEF11 (Rho guanine nucleotide exchange factor 11 [Source:HGNC Symbol;Acc:HGNC:14580])

HSP 1 Score: 49.2914 bits (116), Expect = 4.405e-6
Identity = 23/55 (41.82%), Postives = 35/55 (63.64%), Query Frame = 1 
Query: 1441 GFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFR 1605
            GFG T+ G +PV+V  V  D +A  AG+  GD IIK++   V+QS+   VV++ +
Sbjct:   16 GFGLTVSGDNPVFVQSVRKDGAAMRAGVQQGDRIIKVNGTLVTQSNHLEVVKLIK 70
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Nematostella
Match: EDO44925 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUL8])

HSP 1 Score: 65.855 bits (159), Expect = 3.170e-11
Identity = 43/129 (33.33%), Postives = 74/129 (57.36%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHV-QNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI+L       +I+  L+EA NL  M+ N +S+P+V+++LL   P+  N     +++F  + SPVF+++F F I   D  +R+ I  +   +    + +G +SFG+ + Q K  V GW+ LL +E G
Sbjct:   60 RGRIHL-------KISYELREARNLMPMDPNGLSDPYVKVKLL---PDPDNTSKKKTKIFKESLSPVFNETFEFKIQNKDKDRRLSIEVWDWDRTTRNDFMGSLSFGVSELQ-KNGVEGWFKLLSQEEG 177
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Nematostella
Match: EDO34828 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNC4])

HSP 1 Score: 50.447 bits (119), Expect = 2.779e-7
Identity = 31/106 (29.25%), Postives = 54/106 (50.94%), Query Frame = 1 
Query: 1375 TNLTNSNVGYQIIEVKLVKGLRGFGFTLCG---GSPVYVSHVDVDSSAELAG-IHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRS-----PPQLSYR 1665
            T  T+ +   Q  EV L+KG +G G +L G   G P+Y+  +    SA L G +   D+I++++  ++ + +    + + R CP  V++ + RS     PP   YR
Sbjct:   30 TQYTDYSAEEQPFEVHLIKGPQGLGMSLTGGESGGPIYIKRLVPGGSAALCGQLQVNDVILQVNGKSLDRLTYREALSILRNCPPEVRLLVKRSRGSSYPPYPGYR 135
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Nematostella
Match: EDO47906 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKG0])

HSP 1 Score: 48.9062 bits (115), Expect = 6.642e-6
Identity = 24/55 (43.64%), Postives = 32/55 (58.18%), Query Frame = 1 
Query: 1441 GFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFR 1605
            GFGFTL G +PV V  VD  S A  A + PGD I++I+  NV   +   VV + +
Sbjct:  226 GFGFTLTGNAPVCVRSVDKGSPAAQARLKPGDHILEINGLNVRNKTHAHVVELLK 280
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Medaka
Match: ENSORLT00000021998.2 (regulator of G-protein signaling 3 [Source:NCBI gene;Acc:101174109])

HSP 1 Score: 67.781 bits (164), Expect = 3.999e-11
Identity = 32/93 (34.41%), Postives = 50/93 (53.76%), Query Frame = 1 
Query: 1375 TNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQ 1653
            T L+ SN G Q + V +++G  GFGFT+C  SPV V  VD    A L+G+  GD +++++   V       +    R CP  + + +WR  P+
Sbjct:  423 TTLSASN-GSQHLRVSILRGEDGFGFTICSDSPVKVQAVDPGGPAHLSGLRQGDSVMQLNGLPVETWKCVDLAHAIRSCPSQITLVVWRGLPE 514

HSP 2 Score: 59.3066 bits (142), Expect = 1.600e-8
Identity = 33/137 (24.09%), Postives = 70/137 (51.09%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVIST----YHVQNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIGYRKHWK 1308
            +G++ L++  +  ++ I + EA  L   ++   + +V++ + S+     N     +   PN  +P +D+S S  +       R+++S     +  + ++L  +GCMSF I     ++Q++ W+YLL E+ G  KH +
Sbjct:  215 RGQLKLSVTPEAGQLAIHVHEARGLMEKSHRSCDSYVKVSVTSDR---HNSVWMKTRTVPNEKNPKYDQSVSLCVRG-KLQSRLLVSVCRRLHDCRGSQL--IGCMSFSIGSLVSRSQLTDWFYLLNEDFGRSKHLR 345
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Medaka
Match: rgs12b (regulator of G-protein signaling 12 [Source:NCBI gene;Acc:101172559])

HSP 1 Score: 60.4622 bits (145), Expect = 7.376e-9
Identity = 30/85 (35.29%), Postives = 50/85 (58.82%), Query Frame = 1 
Query: 1405 QIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTL------WR 1641
            +I  V++ +G  G+GFTL G SP  +S +   S A+  G+H GD I+ +++ NVS++S E VV++   C   +K+ +      WR
Sbjct:   31 RIHTVEVARGRTGYGFTLTGQSPCVLSCILKGSPADYVGLHSGDYILAVNDINVSKASHEDVVKLIGRCSGVLKLVISEGDCNWR 115
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Medaka
Match: rgs12b (regulator of G-protein signaling 12 [Source:NCBI gene;Acc:101172559])

HSP 1 Score: 60.4622 bits (145), Expect = 7.390e-9
Identity = 30/85 (35.29%), Postives = 50/85 (58.82%), Query Frame = 1 
Query: 1405 QIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTL------WR 1641
            +I  V++ +G  G+GFTL G SP  +S +   S A+  G+H GD I+ +++ NVS++S E VV++   C   +K+ +      WR
Sbjct:   31 RIHTVEVARGRTGYGFTLTGQSPCVLSCILKGSPADYVGLHSGDYILAVNDINVSKASHEDVVKLIGRCSGVLKLVISEGDCNWR 115
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Medaka
Match: PRKCB (protein kinase C beta [Source:NCBI gene;Acc:105353642])

HSP 1 Score: 58.151 bits (139), Expect = 3.505e-8
Identity = 36/129 (27.91%), Postives = 74/129 (57.36%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQ-NNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI +T   + + +T+ +KEA NL  M+ N +S+P+V+++L   +P+ ++     ++      +P ++++F F++   D  +R+ +  +     +  + +G +SFGI + Q K  V GW+ LL +E G
Sbjct:  161 RGRIQITAEVKTNVLTVTIKEARNLVPMDPNGLSDPYVKLKL---IPDPRSESKQKTKTIKCCLNPTWNETFKFHLKEYDKDRRLSVEVWDWDLTSRNDFMGSLSFGISELQ-KQGVDGWFKLLSQEEG 285
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Medaka
Match: PRKCB (protein kinase C beta [Source:NCBI gene;Acc:105353642])

HSP 1 Score: 57.7658 bits (138), Expect = 4.007e-8
Identity = 36/129 (27.91%), Postives = 74/129 (57.36%), Query Frame = 1 
Query:  910 KGRINLTILCQFSRITILLKEADNLRSMN-NSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQ-NNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIG 1290
            +GRI +T   + + +T+ +KEA NL  M+ N +S+P+V+++L   +P+ ++     ++      +P ++++F F++   D  +R+ +  +     +  + +G +SFGI + Q K  V GW+ LL +E G
Sbjct:  161 RGRIQITAEVKTNVLTVTIKEARNLVPMDPNGLSDPYVKLKL---IPDPRSESKQKTKTIKCCLNPTWNETFKFHLKEYDKDRRLSVEVWDWDLTSRNDFMGSLSFGISELQ-KQGVDGWFKLLSQEEG 285
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Planmine SMEST
Match: SMESG000022937.1 (SMESG000022937.1)

HSP 1 Score: 1285.01 bits (3324), Expect = 0.000e+0
Identity = 646/650 (99.38%), Postives = 649/650 (99.85%), Query Frame = 1 
Query:  178 MSTSTQKTFWNATNATSDSGSKNVDYLKVSSVNTAPIVSSTQVDISSDLIGCSDLESILKQQDIKCNDRFLSNHYSLLTVSHSPVLTKNPSRVSNFKNQNKTQCCRPKPHFRRKISNRSHTWNDAAXXXXXXXGPVQFRAATDGEKSPVNSILQSNENITDSLSVENIPRLNFKSNFNNLIPMTVDTKTNNDLSNKTEPIRNSTNNTQLISRSLSPDESYLRNSDSKSETKFPIKPEFTTLAPCKGRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPAVPFNMHNSKTYPCIRAQLLPRDQSLNLTGAFTNSNGQMTKPMDSDSGNSGHDFQWDNNNRGRLDQRSVHFNSNVTEVDKTLSYAIMKSSQSPNVGIFEHGEVEKSSIVCSNNFPTRPPGEGSSNPNQIYPNLSGSEIINRLQYQGHLKKV 2127
            MSTSTQKTFWNATNATSDSGSKNVDYLKVSSVNTAPIVSSTQVDISSDLIGCSDLESILKQQDIKCNDRFLSNHYSLLTVSHSPVLTKNPSRVSNFKNQNKTQCCRPKPHFRRKISNRSHTWNDAASSISSSSGPVQFRAATDGEKSPVNSILQSNENITDSLSVENIPRLNFKSNFNNLIPMTVDTKTNNDLSNKTEPIRNSTNNTQLISRSLSPDESYLRNSDSKSETKFPIKPEFTTLAPCKGRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIGYRKH KAGFLSVNKTNSVSNSVLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPAVPFNMHNSKTYPCIRAQLLPRDQSLN+TGAFTNSNGQMTKPMDSDSGNSGHDFQWDNNNRGRLDQRSVHFNSNVTEVDKTLSYAIMKSSQSPNVGIFEHGEVEKSSI+CSNNFPTRPPGEGSSNPNQIYPNLSGSEIINRLQYQGHLKK+
Sbjct:    1 MSTSTQKTFWNATNATSDSGSKNVDYLKVSSVNTAPIVSSTQVDISSDLIGCSDLESILKQQDIKCNDRFLSNHYSLLTVSHSPVLTKNPSRVSNFKNQNKTQCCRPKPHFRRKISNRSHTWNDAASSISSSSGPVQFRAATDGEKSPVNSILQSNENITDSLSVENIPRLNFKSNFNNLIPMTVDTKTNNDLSNKTEPIRNSTNNTQLISRSLSPDESYLRNSDSKSETKFPIKPEFTTLAPCKGRINLTILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIGYRKHLKAGFLSVNKTNSVSNSVLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPAVPFNMHNSKTYPCIRAQLLPRDQSLNITGAFTNSNGQMTKPMDSDSGNSGHDFQWDNNNRGRLDQRSVHFNSNVTEVDKTLSYAIMKSSQSPNVGIFEHGEVEKSSIICSNNFPTRPPGEGSSNPNQIYPNLSGSEIINRLQYQGHLKKL 650
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Planmine SMEST
Match: SMESG000057434.1 (SMESG000057434.1)

HSP 1 Score: 142.51 bits (358), Expect = 1.180e-35
Identity = 141/532 (26.50%), Postives = 231/532 (43.42%), Query Frame = 1 
Query:  880 KPEFTTLAPCKGRINLTI-LCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPAVPFNMHNSKTYPCIRAQLLPRDQSLNLTGAFTNSNGQMTKPMDSDSGNSGHDFQWDNNNRGRLDQRSVHFNSNVTEVDKTLSYAIMKSSQSPNVGIFEHGEVEK---SSIVCSNNFPTRPPGEGSSNPN-----QIYPNLSGSEIINRLQYQGHLKKVDFS-QMSPNLEIYGPASLKEGNCLFPVHIYLFSQVLLVGQLEPDGHITVIKEPIYCSKICYANIPAFCYDEIILQYINEVGRKQFIYFQATNIKEWLNRIQRHMIYH 2445
            K  F  LAPCKGR+ L + +   S + + +  A+  ++     S  F++I   S+    Q  PL    +   + S  +D    FN   L   +RI+IS Y +    +  LG MSFGIKK      ++GWYYLLKE IG +KH K          ++  S+  D   TN T++ +  ++I+V L +    FGFT+CG  P YV  V+ +S+A+   +  GD+I+KI++  V           F    K++   L   P ++S          ++ SKT P             +    F NS G    P D                        + F+S      K++S+     +    +  FE    +    S++ C  N      G  + NP      +I  + + + +I+RLQY G+++ V F      ++E      L E      V + L S ++L+  +EPDG  TVIK PI    I Y ++P     +++LQY  E G  + I+    +++ + N ++   + H
Sbjct:   34 KTSFHVLAPCKGRLLLEMSVHNQSTLKVHIIRAEFPKTSFKEPSETFIKINFTSSSVEKQMSPL-AKRISNTDFSFRYDGYCLFN--KLHMNQRIIISAYVMDGTNVMILGSMSFGIKKIWESEMLTGWYYLLKENIGSKKHLKV------YQETIPRSITADVLCTNTTDATL--ELIKVDLRRKGNEFGFTICGNQPPYVGKVEKNSAADDCNLRSGDVIVKIEHLLV-----------FSCSAKAIAQILRLYPDEVS--------LTIYRSKTQP-------------SNCDLFVNSVGSPKSPKDV-----------------------IKFHSK----SKSISWIKKIMTTKKKINKFEENFPQNYYVSNLGCKMN-ECHIDGNLNKNPVSSPDIEIVKDNNKNNVIDRLQYLGNIQSVKFPPNHGAHVEYITNLWLIETTSRISVTVLLLSHLILITHVEPDGFYTVIKRPILIESIMYLSMPISTTYDLVLQYRGEGGANETIHLHGDSVEYFTNLLKEKRVTH 494
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Planmine SMEST
Match: SMESG000057434.1 (SMESG000057434.1)

HSP 1 Score: 142.124 bits (357), Expect = 1.350e-34
Identity = 142/534 (26.59%), Postives = 231/534 (43.26%), Query Frame = 1 
Query:  880 KPEFTTLAPCKGRINLTI-LCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDSEVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELESLGCMSFGIKKFQIKTQVSGWYYLLKEEIGYRKHWKAGFLXXXXXXXXXXXXLQDSKLTNLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPAVPFNMHNSKTYP--CIRAQLLPRDQSLNLTGAFTNSNGQMTKPMDSDSGNSGHDFQWDNNNRGRLDQRSVHFNSNVTEVDKTLSYAIMKSSQSPNVGIFEHGEVEK---SSIVCSNNFPTRPPGEGSSNPN-----QIYPNLSGSEIINRLQYQGHLKKVDFS-QMSPNLEIYGPASLKEGNCLFPVHIYLFSQVLLVGQLEPDGHITVIKEPIYCSKICYANIPAFCYDEIILQYINEVGRKQFIYFQATNIKEWLNRIQRHMIYH 2445
            K  F  LAPCKGR+ L + +   S + + +  A+  ++     S  F++I   S+    Q  PL    +   + S  +D    FN   L   +RI+IS Y +    +  LG MSFGIKK      ++GWYYLLKE IG +KH K          ++  S+  D   TN T++ +  ++I+V L +    FGFT+CG  P YV  V+ +S+A+   +  GD+I+KI++  V           F    K++   L   P ++S          ++ SKT P  C                 F NS G    P D                        + F+S      K++S+     +    +  FE    +    S++ C  N      G  + NP      +I  + + + +I+RLQY G+++ V F      ++E      L E      V + L S ++L+  +EPDG  TVIK PI    I Y ++P     +++LQY  E G  + I+    +++ + N ++   + H
Sbjct:   34 KTSFHVLAPCKGRLLLEMSVHNQSTLKVHIIRAEFPKTSFKEPSETFIKINFTSSSVEKQMSPL-AKRISNTDFSFRYDGYCLFN--KLHMNQRIIISAYVMDGTNVMILGSMSFGIKKIWESEMLTGWYYLLKENIGSKKHLKV------YQETIPRSITADVLCTNTTDATL--ELIKVDLRRKGNEFGFTICGNQPPYVGKVEKNSAADDCNLRSGDVIVKIEHLLV-----------FSCSAKAIAQILRLYPDEVS--------LTIYRSKTQPSNC---------------DLFVNSVGSPKSPKDV-----------------------IKFHSK----SKSISWIKKIMTTKKKINKFEENFPQNYYVSNLGCKMN-ECHIDGNLNKNPVSSPDIEIVKDNNKNNVIDRLQYLGNIQSVKFPPNHGAHVEYITNLWLIETTSRISVTVLLLSHLILITHVEPDGFYTVIKRPILIESIMYLSMPISTTYDLVLQYRGEGGANETIHLHGDSVEYFTNLLKEKRVTH 494
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Planmine SMEST
Match: SMESG000022872.1 (SMESG000022872.1)

HSP 1 Score: 51.2174 bits (121), Expect = 3.501e-6
Identity = 21/57 (36.84%), Postives = 39/57 (68.42%), Query Frame = 1 
Query: 1441 GFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMC 1611
            GFGFT+ G  P+ V +V+ +S+AE +G+  GD ++ +D++++  SS E +V++   C
Sbjct:  530 GFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKC 586
[Close]
BLAST of Regulator of G-protein signaling 3 vs. Planmine SMEST
Match: SMESG000022872.1 (SMESG000022872.1)

HSP 1 Score: 51.2174 bits (121), Expect = 3.579e-6
Identity = 21/57 (36.84%), Postives = 39/57 (68.42%), Query Frame = 1 
Query: 1441 GFGFTLCGGSPVYVSHVDVDSSAELAGIHPGDMIIKIDNFNVSQSSTEAVVRMFRMC 1611
            GFGFT+ G  P+ V +V+ +S+AE +G+  GD ++ +D++++  SS E +V++   C
Sbjct:  524 GFGFTVKGQGPMKVVNVEKNSNAEKSGLKVGDFVLSMDDYDLRWSSQEVLVQITAKC 580
The following BLAST results are available for this feature:
BLAST of Regulator of G-protein signaling 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RGS31.102e-2425.71regulator of G protein signaling 3 [Source:HGNC Sy... [more]
RGS31.102e-2425.71regulator of G protein signaling 3 [Source:HGNC Sy... [more]
RGS31.828e-2426.67regulator of G protein signaling 3 [Source:HGNC Sy... [more]
PRKCG2.999e-930.00protein kinase C gamma [Source:HGNC Symbol;Acc:HGN... [more]
RGS37.339e-831.76regulator of G protein signaling 3 [Source:HGNC Sy... [more]
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pkc53E2.314e-827.91gene:FBgn0003091 transcript:FBtr0305069[more]
Pkc53E2.839e-827.91gene:FBgn0003091 transcript:FBtr0112819[more]
Pkc53E2.839e-827.91gene:FBgn0003091 transcript:FBtr0305070[more]
Pkc53E2.970e-827.91gene:FBgn0003091 transcript:FBtr0331960[more]
Pkc53E2.970e-827.91gene:FBgn0003091 transcript:FBtr0087049[more]
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rgs3b5.068e-1826.69regulator of G protein signaling 3b [Source:ZFIN;A... [more]
arhgef111.722e-833.06Rho guanine nucleotide exchange factor (GEF) 11 [S... [more]
prkcab1.927e-829.46protein kinase C, alpha, b [Source:ZFIN;Acc:ZDB-GE... [more]
prkcaa2.147e-825.58protein kinase C, alpha, a [Source:ZFIN;Acc:ZDB-GE... [more]
prkcab2.194e-829.46protein kinase C, alpha, b [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RGS129.705e-938.89regulator of G-protein signaling 12 [Source:NCBI g... [more]
RGS121.036e-838.89regulator of G-protein signaling 12 [Source:NCBI g... [more]
RGS121.051e-838.89regulator of G-protein signaling 12 [Source:NCBI g... [more]
rai23.483e-634.88retinoic acid induced 2 [Source:Xenbase;Acc:XB-GEN... [more]
rai23.572e-634.88retinoic acid induced 2 [Source:Xenbase;Acc:XB-GEN... [more]
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rgs36.576e-2626.25regulator of G-protein signaling 3 [Source:MGI Sym... [more]
Rgs39.392e-2626.25regulator of G-protein signaling 3 [Source:MGI Sym... [more]
Prkcg6.230e-1031.54Protein kinase C gamma type [Source:UniProtKB/Swi... [more]
Prkcg6.230e-1031.54Protein kinase C gamma type [Source:UniProtKB/Swi... [more]
Prkcg6.230e-1031.54protein kinase C, gamma [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Regulator of G-protein signaling 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P49796|RGS3_HUMAN5.293e-2425.71Regulator of G-protein signaling 3 OS=Homo sapiens... [more]
sp|P63319|KPCG_RAT4.727e-931.54Protein kinase C gamma type OS=Rattus norvegicus O... [more]
sp|P63318|KPCG_MOUSE4.727e-931.54Protein kinase C gamma type OS=Mus musculus OX=100... [more]
sp|P05128|KPCG_BOVIN8.149e-930.77Protein kinase C gamma type (Fragment) OS=Bos taur... [more]
sp|Q4R4U2|KPCG_MACFA1.014e-830.77Protein kinase C gamma type OS=Macaca fascicularis... [more]
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BLAST of Regulator of G-protein signaling 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3IK276.545e-3333.60regulator of G-protein signaling 3-like OS=Lingula... [more]
A0A183APU19.267e-3350.78PDZ domain-containing protein OS=Echinostoma capro... [more]
A0A3P8HKZ69.437e-3350.78PDZ domain-containing protein OS=Echinostoma capro... [more]
A0A504XP415.360e-3053.13Delphilin OS=Fasciola gigantica OX=46835 GN=FGIG_1... [more]
A0A4E0S4365.474e-3053.13Uncharacterized protein OS=Fasciola hepatica OX=61... [more]
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rgs3b4.384e-1924.32regulator of G-protein signaling 3 [Source:NCBI ge... [more]
rgs3b1.621e-1824.03regulator of G-protein signaling 3 [Source:NCBI ge... [more]
prkcbb1.613e-828.68protein kinase C beta type [Source:NCBI gene;Acc:1... [more]
prkcbb2.440e-828.68protein kinase C beta type [Source:NCBI gene;Acc:1... [more]
ENSAMXT00000048876.11.125e-740.91pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ARHGEF114.405e-641.82Rho guanine nucleotide exchange factor 11 [Source:... [more]
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO449253.170e-1133.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO348282.779e-729.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO479066.642e-643.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Regulator of G-protein signaling 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000021998.23.999e-1134.41regulator of G-protein signaling 3 [Source:NCBI ge... [more]
rgs12b7.376e-935.29regulator of G-protein signaling 12 [Source:NCBI g... [more]
rgs12b7.390e-935.29regulator of G-protein signaling 12 [Source:NCBI g... [more]
PRKCB3.505e-827.91protein kinase C beta [Source:NCBI gene;Acc:105353... [more]
PRKCB4.007e-827.91protein kinase C beta [Source:NCBI gene;Acc:105353... [more]
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BLAST of Regulator of G-protein signaling 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000022937.10.000e+099.38SMESG000022937.1[more]
SMESG000057434.11.180e-3526.50SMESG000057434.1[more]
SMESG000057434.11.350e-3426.59SMESG000057434.1[more]
SMESG000022872.13.501e-636.84SMESG000022872.1[more]
SMESG000022872.13.579e-636.84SMESG000022872.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015176 ID=SMED30015176|Name=Regulator of G-protein signaling 3|organism=Schmidtea mediterranea sexual|type=transcript|length=2580bp
CGGCCAGCTACTATCAACCGTTTTATCAGTAGAAAAATGTTTAATGCGAT
TGAACTAAAACGGGATAACATTTAAGAGAAATATTTACTAGGATTTTTTT
TTGTTTTTTTTCACTCTTGCACCTACCTCGAAATTGCGAGTAAAAAAAGA
GGGAAATTAGTCAAACTTCACTGATAAATGTCGACTTCGACACAAAAAAC
ATTTTGGAATGCAACTAATGCCACCTCAGATTCAGGCAGTAAAAACGTTG
ACTATTTGAAAGTAAGCTCCGTTAACACAGCTCCTATTGTTTCATCTACT
CAAGTGGATATTTCAAGCGATTTGATTGGCTGCAGCGATTTGGAGAGTAT
ATTAAAACAACAAGACATAAAATGCAACGATAGATTTCTTTCCAATCACT
ATTCTCTTTTGACAGTTTCTCATTCACCGGTTTTGACTAAAAATCCATCG
AGAGTTTCGAATTTTAAAAATCAAAACAAAACTCAGTGCTGTCGTCCCAA
GCCGCATTTTCGACGGAAAATCTCCAATCGATCTCACACTTGGAATGATG
CTGCCAGTTCGATTAGTTCTTCATCTGGACCGGTGCAATTTCGAGCGGCA
ACCGATGGAGAAAAGTCTCCAGTGAATTCAATTCTTCAATCGAATGAAAA
CATTACCGACTCTTTGTCAGTTGAAAATATTCCAAGATTGAATTTCAAGT
CAAATTTTAATAATTTAATCCCCATGACTGTTGATACTAAAACAAACAAT
GATCTCTCGAACAAAACCGAACCGATCCGAAACTCAACAAATAACACTCA
ACTCATTTCCAGATCTCTCTCACCCGATGAAAGTTATCTGAGAAATTCCG
ACAGTAAAAGTGAAACAAAATTTCCCATTAAACCCGAATTTACAACTTTG
GCTCCATGCAAAGGCAGAATCAATCTCACAATACTATGCCAGTTCTCAAG
GATAACCATTTTGCTCAAAGAAGCTGATAATTTACGGTCCATGAATAATT
CGGTCTCCAATCCATTTGTTCGAATCCAGTTACTATCAAATCTACCAAAC
GGACAAAATATTCCGCTTTTTGATTCAGAGGTTTTCCCGAATAACTCAAG
TCCGGTATTTGATAAAAGTTTCAGTTTCAACATTTCTCCTTTGGATTATT
ACAAAAGAATTGTCATCTCCACATATCACGTTCAAAATAATGAATTAGAA
TCTTTAGGCTGTATGTCTTTTGGAATAAAGAAATTTCAAATTAAAACTCA
GGTTTCAGGATGGTATTATCTTTTGAAAGAGGAAATTGGATATAGAAAAC
ATTGGAAAGCTGGATTTTTGTCAGTAAACAAAACAAATTCTGTCAGTAAT
TCGGTTTTGCAAGATTCAAAATTGACAAATTTGACAAACTCTAATGTTGG
ATATCAAATAATAGAAGTGAAATTGGTTAAAGGCCTTCGTGGATTCGGAT
TTACACTTTGCGGAGGATCACCAGTTTATGTCAGTCATGTCGACGTTGAT
TCGTCGGCGGAATTAGCCGGAATTCACCCGGGGGATATGATAATCAAGAT
TGACAATTTCAATGTATCTCAATCATCAACAGAAGCCGTCGTCAGAATGT
TTCGAATGTGTCCAAAATCTGTCAAGGTTACCCTGTGGAGATCTCCGCCA
CAGTTGTCTTATCGACCTCTTCCAGCAGTGCCATTCAATATGCACAACAG
TAAAACATATCCATGTATTCGAGCACAGTTATTACCTCGAGACCAATCGT
TGAATCTCACGGGTGCTTTCACAAATTCAAATGGCCAAATGACCAAACCC
ATGGACTCCGATAGCGGTAATTCCGGACACGATTTTCAATGGGATAATAA
CAACAGGGGTCGACTAGATCAGAGATCGGTTCATTTCAATTCGAATGTTA
CTGAAGTGGACAAGACATTATCATATGCAATAATGAAATCAAGTCAATCA
CCGAATGTAGGAATTTTCGAACATGGAGAAGTAGAGAAAAGTTCAATTGT
ATGTAGTAATAATTTTCCCACGCGTCCTCCAGGAGAAGGTAGTAGCAATC
CGAATCAGATTTATCCAAATTTATCAGGGTCAGAAATAATAAACAGGTTA
CAATATCAAGGTCACTTGAAAAAAGTTGATTTTAGTCAAATGTCACCAAA
TCTTGAAATTTATGGTCCAGCTTCGTTGAAAGAGGGCAACTGTTTGTTTC
CAGTTCACATATATTTATTTTCTCAAGTTCTATTGGTCGGACAGCTTGAA
CCTGACGGTCATATTACGGTTATCAAAGAACCAATATATTGCTCTAAGAT
ATGTTATGCAAATATTCCAGCTTTTTGTTACGACGAAATAATTCTTCAAT
ATATTAACGAAGTCGGTCGAAAGCAATTTATCTATTTCCAAGCTACGAAT
ATCAAAGAATGGTTGAACAGGATCCAAAGACACATGATCTACCACTGCAA
TTGGTGGATGCCAAACATAGCCTAGCGTAAAATTCATCATTTATGCAAAA
TCTCGCATTCGGCTATTTGTGTTATTCTCATCTTATTTTGTTCAAATTTA
TTGTTTTCTCGATTTTTTCTAGATTTCCAC
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protein sequence of SMED30015176-orf-1

>SMED30015176-orf-1 ID=SMED30015176-orf-1|Name=SMED30015176-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=766bp
MSTSTQKTFWNATNATSDSGSKNVDYLKVSSVNTAPIVSSTQVDISSDLI
GCSDLESILKQQDIKCNDRFLSNHYSLLTVSHSPVLTKNPSRVSNFKNQN
KTQCCRPKPHFRRKISNRSHTWNDAASSISSSSGPVQFRAATDGEKSPVN
SILQSNENITDSLSVENIPRLNFKSNFNNLIPMTVDTKTNNDLSNKTEPI
RNSTNNTQLISRSLSPDESYLRNSDSKSETKFPIKPEFTTLAPCKGRINL
TILCQFSRITILLKEADNLRSMNNSVSNPFVRIQLLSNLPNGQNIPLFDS
EVFPNNSSPVFDKSFSFNISPLDYYKRIVISTYHVQNNELESLGCMSFGI
KKFQIKTQVSGWYYLLKEEIGYRKHWKAGFLSVNKTNSVSNSVLQDSKLT
NLTNSNVGYQIIEVKLVKGLRGFGFTLCGGSPVYVSHVDVDSSAELAGIH
PGDMIIKIDNFNVSQSSTEAVVRMFRMCPKSVKVTLWRSPPQLSYRPLPA
VPFNMHNSKTYPCIRAQLLPRDQSLNLTGAFTNSNGQMTKPMDSDSGNSG
HDFQWDNNNRGRLDQRSVHFNSNVTEVDKTLSYAIMKSSQSPNVGIFEHG
EVEKSSIVCSNNFPTRPPGEGSSNPNQIYPNLSGSEIINRLQYQGHLKKV
DFSQMSPNLEIYGPASLKEGNCLFPVHIYLFSQVLLVGQLEPDGHITVIK
EPIYCSKICYANIPAFCYDEIILQYINEVGRKQFIYFQATNIKEWLNRIQ
RHMIYHCNWWMPNIA*
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Aliases
The feature 'Regulator of G-protein signaling 3' has the following synonyms
Synonym
Smed_17151
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0005085guanyl-nucleotide exchange factor activity
GO:0005515protein binding
GO:0005089Rho guanyl-nucleotide exchange factor activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000017photoreceptor neuron
PLANA:0000103central nervous system
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR035892C2_domain_sf
IPR036034PDZ_sf
IPR001478PDZ
IPR000008C2_dom
Vocabulary: biological process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
GO:0043547positive regulation of GTPase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001478PDZ domainSMARTSM00228pdz_newcoord: 421..490
e-value: 1.8E-15
score: 67.4
IPR001478PDZ domainPFAMPF00595PDZcoord: 414..486
e-value: 5.9E-11
score: 42.6
IPR001478PDZ domainPROSITEPS50106PDZcoord: 413..490
score: 14.355
IPR000008C2 domainSMARTSM00239C2_3ccoord: 258..362
e-value: 1.8E-7
score: 40.8
IPR000008C2 domainPFAMPF00168C2coord: 259..364
e-value: 1.8E-7
score: 31.4
IPR000008C2 domainPROSITEPS50004C2coord: 257..347
score: 10.264
IPR035892C2 domain superfamilyGENE3DG3DSA:2.60.40.150coord: 241..379
e-value: 4.7E-18
score: 67.1
IPR036034PDZ superfamilyGENE3DG3DSA:2.30.42.10coord: 409..497
e-value: 5.1E-21
score: 76.5
IPR036034PDZ superfamilySUPERFAMILYSSF50156PDZ domain-likecoord: 405..495
NoneNo IPR availablePANTHERPTHR46848FAMILY NOT NAMEDcoord: 191..506
NoneNo IPR availableCDDcd00992PDZ_signalingcoord: 411..486
e-value: 8.82291E-18
score: 76.4514
NoneNo IPR availableSUPERFAMILYSSF49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 255..368