Calponin

Overview


Name	Calponin
Smed ID	SMED30015168
Length (bp)	474

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Calponin (SMED30015168) t-SNE clustered cells

Violin plots show distribution of expression levels for Calponin (SMED30015168) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calponin (SMED30015168) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Calponin (SMED30015168) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30015168

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 19

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30015168	h1SMcG0017536	Contig48905	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015168	h1SMcG0017536	Contig48905	newmark_ests	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015168	h1SMcG0017536	dd_Smed_v4_635_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30015168	h1SMcG0017536	dd_Smed_v4_635_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30015168	h1SMcG0017536	dd_Smed_v4_635_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015168	h1SMcG0017536	dd_Smed_v4_273_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30015168	h1SMcG0017536	dd_Smed_v4_273_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30015168	h1SMcG0017536	dd_Smed_v4_273_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015168	h1SMcG0017536	dd_Smed_v4_533_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30015168	h1SMcG0017536	dd_Smed_v4_533_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30015168	h1SMcG0017536	dd_Smed_v4_533_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015168	h1SMcG0017536	dd_Smed_v4_450_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30015168	h1SMcG0017536	dd_Smed_v4_450_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30015168	h1SMcG0017536	dd_Smed_v4_450_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
pharynx musculature	SMED30015168	h1SMcG0017536	dd_Smed_v6_273_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30015168	h1SMcG0017536	dd_Smed_v6_273_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
pharynx musculature	SMED30015168	h1SMcG0017536	dd_Smed_v6_450_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30015168	h1SMcG0017536	dd_Smed_v6_450_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parapharyngeal region	SMED30015168	h1SMcG0017536	PL030005A20G01	smed_ncbi_20240424	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Calponin vs. Ensembl Human
Match: CNN1 (calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155])

HSP 1 Score: 79.337 bits (194), Expect = 4.015e-18
Identity = 54/117 (46.15%), Postives = 71/117 (60.68%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIR--CDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIR 405
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D +
Sbjct:   15 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN--VSLQMGSNKGASQRGMTVYGLPRQVYDPK 127

HSP 2 Score: 59.3066 bits (142), Expect = 1.084e-10
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:   15 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 110

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BLAST of Calponin vs. Ensembl Human
Match: CNN1 (calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155])

HSP 1 Score: 78.9518 bits (193), Expect = 7.013e-18
Identity = 54/117 (46.15%), Postives = 71/117 (60.68%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIR 405
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D +
Sbjct:  109 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPK 221

HSP 2 Score: 58.5362 bits (140), Expect = 2.288e-10
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  109 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 204

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Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIR 405
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D +
Sbjct:  109 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPK 221

HSP 2 Score: 58.5362 bits (140), Expect = 2.288e-10
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  109 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 204

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BLAST of Calponin vs. Ensembl Human
Match: CNN1 (calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155])

HSP 1 Score: 79.337 bits (194), Expect = 1.031e-17
Identity = 54/118 (45.76%), Postives = 71/118 (60.17%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIRC 408
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D + 
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKY 272

HSP 2 Score: 58.5362 bits (140), Expect = 3.005e-10
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 254

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BLAST of Calponin vs. Ensembl Human
Match: CNN3 (calponin 3 [Source:HGNC Symbol;Acc:HGNC:2157])

HSP 1 Score: 72.7886 bits (177), Expect = 2.065e-15
Identity = 51/117 (43.59%), Postives = 70/117 (59.83%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIAD--IRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIRC 408
            G++ IGLQ G+NK ASQ GM+  G  RH+ D  ++ D+  D+    I LQ G+NKGA+QAGM   G +R I D    L+  D   + I LQ G+NK ASQ GMS+  + R + D + 
Sbjct:  114 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQT--TISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDN--STISLQMGTNKVASQKGMSVYGLGRQVYDPKY 226

HSP 2 Score: 45.8246 bits (107), Expect = 7.763e-6
Identity = 37/107 (34.58%), Postives = 55/107 (51.40%), Query Frame = 1

Query:  208 LQAGSNKGATQAGMRIGGQR---FINDVSSGLEMS-------DEGK-----TCIGLQAGSNKGASQTGMS-MGAVRHIAD--IRCDEMSDEAKGVIGLQAGSNKGAT 474
            LQ GS K   ++ +     +   F   +  G++ +       DEGK     + IGLQ G+NK ASQ GM+  G  RH+ D  ++ D+  D+    I LQ G+NKGA+
Sbjct:   65 LQPGSVKKVNESSLNWPQAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQT--TISLQMGTNKGAS 169

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BLAST of Calponin vs. Ensembl Celegans
Match: clik-1 (CaLponIn-liKe proteins [Source:UniProtKB/TrEMBL;Acc:H2L0M6])

HSP 1 Score: 70.8626 bits (172), Expect = 6.890e-15
Identity = 59/157 (37.58%), Postives = 85/157 (54.14%), Query Frame = 1

Query:   61 MSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIAD-IRCD---EMSDEA-----KGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGL----EMSDEGKTC----IGLQAGSNKGASQTGMSMGAVRHIADI-RCDEMSDEAKGVIGLQAGSNKGA 471
            M  EG   I +QAGSNK ASQ GM+  G  R + D ++ D   E++DE      KG   LQ+G+NK A+Q G    G  R +N  + G     E+ +E        + LQ+G+NK ASQ GM+   +  I D+ R ++   +++G I LQ G+NK A
Sbjct:   97 MRSEG--IIPIQAGSNKYASQKGMTGFGVPRDVIDKVKSDNLAEITDEKKIANLKGSTWLQSGTNKFASQKGQSGFGAVRDVNYKTKGTGGASEVPEEKARASDGIVPLQSGTNKLASQAGMTGIGMPRIVDVRRTNDQDRDSQGFIHLQMGTNKFA 251

HSP 2 Score: 62.003 bits (149), Expect = 8.247e-12
Identity = 52/143 (36.36%), Postives = 74/143 (51.75%), Query Frame = 1

Query:   58 EMSDEGKTC-----IGLQAGSNKGASQTGMS-MGAVRHI---------ADIRCDEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKG 435
            E++DE K         LQ+G+NK ASQ G S  GAVR +         A    +E +  + G++ LQ+G+NK A+QAGM  IG  R + DV    +   + +  I LQ G+NK A+Q GM+  G  RH       +  DE +G
Sbjct:  138 EITDEKKIANLKGSTWLQSGTNKFASQKGQSGFGAVRDVNYKTKGTGGASEVPEEKARASDGIVPLQSGTNKLASQAGMTGIGMPRIV-DVRRTNDQDRDSQGFIHLQMGTNKFANQAGMTGFGMPRH----NITKYKDEVRG 275

HSP 3 Score: 53.1434 bits (126), Expect = 9.881e-9
Identity = 46/123 (37.40%), Postives = 65/123 (52.85%), Query Frame = 1

Query:  163 IRCDEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQR-FINDVSSG--LEMSDEGKTC-----IGLQAGSNKGASQTGMS-MGAVRHI---------ADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            I   E    ++G+I +QAGSNK A+Q GM   G  R  I+ V S    E++DE K         LQ+G+NK ASQ G S  GAVR +         A    +E +  + G++ LQ+G+NK A+
Sbjct:   90 IHTKEKLMRSEGIIPIQAGSNKYASQKGMTGFGVPRDVIDKVKSDNLAEITDEKKIANLKGSTWLQSGTNKFASQKGQSGFGAVRDVNYKTKGTGGASEVPEEKARASDGIVPLQSGTNKLAS 212

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Query:   61 MSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIAD-IRCD---EMSDEA-----KGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGL----EMSDEGKTC----IGLQAGSNKGASQTGMSMGAVRHIADI-RCDEMSDEAKGVIGLQAGSNKGA 471
            M  EG   I +QAGSNK ASQ GM+  G  R + D ++ D   E++DE      KG   LQ+G+NK A+Q G    G  R +N  + G     E+ +E        + LQ+G+NK ASQ GM+   +  I D+ R ++   +++G I LQ G+NK A
Sbjct:   97 MRSEG--IIPIQAGSNKYASQKGMTGFGVPRDVIDKVKSDNLAEITDEKKIANLKGSTWLQSGTNKFASQKGQSGFGAVRDVNYKTKGTGGASEVPEEKARASDGIVPLQSGTNKLASQAGMTGIGMPRIVDVRRTNDQDRDSQGFIHLQMGTNKFA 251

HSP 2 Score: 62.003 bits (149), Expect = 8.247e-12
Identity = 52/143 (36.36%), Postives = 74/143 (51.75%), Query Frame = 1

Query:   58 EMSDEGKTC-----IGLQAGSNKGASQTGMS-MGAVRHI---------ADIRCDEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKG 435
            E++DE K         LQ+G+NK ASQ G S  GAVR +         A    +E +  + G++ LQ+G+NK A+QAGM  IG  R + DV    +   + +  I LQ G+NK A+Q GM+  G  RH       +  DE +G
Sbjct:  138 EITDEKKIANLKGSTWLQSGTNKFASQKGQSGFGAVRDVNYKTKGTGGASEVPEEKARASDGIVPLQSGTNKLASQAGMTGIGMPRIV-DVRRTNDQDRDSQGFIHLQMGTNKFANQAGMTGFGMPRH----NITKYKDEVRG 275

HSP 3 Score: 53.1434 bits (126), Expect = 9.881e-9
Identity = 46/123 (37.40%), Postives = 65/123 (52.85%), Query Frame = 1

Query:  163 IRCDEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQR-FINDVSSG--LEMSDEGKTC-----IGLQAGSNKGASQTGMS-MGAVRHI---------ADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            I   E    ++G+I +QAGSNK A+Q GM   G  R  I+ V S    E++DE K         LQ+G+NK ASQ G S  GAVR +         A    +E +  + G++ LQ+G+NK A+
Sbjct:   90 IHTKEKLMRSEGIIPIQAGSNKYASQKGMTGFGVPRDVIDKVKSDNLAEITDEKKIANLKGSTWLQSGTNKFASQKGQSGFGAVRDVNYKTKGTGGASEVPEEKARASDGIVPLQSGTNKLAS 212

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BLAST of Calponin vs. Ensembl Celegans
Match: unc-87 (pep chromosome:WBcel235:I:6761228:6767797:-1 gene:WBGene00006819.1 transcript:F08B6.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-87)

HSP 1 Score: 55.4546 bits (132), Expect = 1.524e-9
Identity = 49/132 (37.12%), Postives = 69/132 (52.27%), Query Frame = 1

Query:   76 KTCIGLQAGSNKGASQTGMS-MGAVR-HIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEG----KTCIGLQAGSNKGASQTGM-SMGAVR-----HIADIRCDEMSDEAK 432
            +T I  Q GSN+ ASQ GM+  G  R  + D      + +++G++ LQ+G+N+ A+QAGM   G  R     + G E+  E     +T I  QAG NKG SQ  M S GA R     H+  I   E  +EA+
Sbjct:  237 QTTIPSQMGSNQYASQKGMTGFGQPRWEVLDPSISWQNRKSQGMVRLQSGTNRFASQAGMIGFGTCRNTTFEAEGGELPYEAMKVSETIIPSQAGWNKGDSQKKMTSFGAPRDVKGKHLKRIWELEYPEEAE 368

HSP 2 Score: 48.521 bits (114), Expect = 4.046e-7
Identity = 48/158 (30.38%), Postives = 76/158 (48.10%), Query Frame = 1

Query:   85 IGLQAGSNKGASQTGMS-MGAVR-------HIADIRCD--EMSDE----AKGVIGLQAGSNKGATQAGM------RIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRH----IADIRCDEMSDEA---KGVIGLQAGSNKGAT 474
            + LQ+G+NK  SQ GM+  G+ R        +A    D  E+ +E    ++G++ LQAG+NK  +Q GM      R    + ++      +     ++ I LQ+G+NK ASQ GM+  G  R     + D    + S E    +  I  Q GSN+ A+
Sbjct:   94 VRLQSGTNKYCSQRGMTGFGSGRDVCREGVRVAQNPADLAELPEEKIRMSEGIVRLQAGTNKYDSQKGMTGFGTGRRETTKMVDSKHPEYDHEKPDQSEIPLQSGTNKFASQKGMTGFGTARRETTKMVDSNHPDYSHECSIDQTTIPSQMGSNQYAS 251

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BLAST of Calponin vs. Ensembl Celegans
Match: clik-2 (CaLponIn-liKe proteins [Source:RefSeq peptide;Acc:NP_509299])

HSP 1 Score: 48.1358 bits (113), Expect = 5.083e-7
Identity = 55/178 (30.90%), Postives = 83/178 (46.63%), Query Frame = 1

Query:   16 IGGQRF-INDVSSGLE----MSDEGKTCIGLQAGSNKGASQTG-MSMGAVRH-IADIRCDEMSDE-AKGVIGLQAGSNKGATQAGMR----IGGQRFINDVSSGLEMSDE----GKTCIGLQAGSNKGASQTGMSMGAVRHIADIRC---------DEMSDEAKGVIGLQAGSNKGAT 474
            IG  RF +  V+   E    +  EG+  I  QAG    ASQ G +SMG  R+ +A IR     D    GV+  Q G+N  A+Q GM     +G  R       GLE+ ++    G       +G NK A+Q G   G    + D+           +E+  +++G++ LQ+G+NK A+
Sbjct:   91 IGASRFQVPKVTYKKEWETILDKEGEKIIPKQAGDYGLASQAGEVSMGGHRNQVALIRGRLPHDRRTHGVLCFQNGTNLFASQTGMSAPPGLGAVRQATQKIEGLELGEDILRRGTEFTPWYSGQNKFATQAGS--GGFLKVRDVLPHTVGGKDIEEELKQKSEGIVPLQSGTNKLAS 266

[Close]

Query:   16 IGGQRF-INDVSSGLE----MSDEGKTCIGLQAGSNKGASQTG-MSMGAVRH-IADIRCDEMSDE-AKGVIGLQAGSNKGATQAGMR----IGGQRFINDVSSGLEMSDE----GKTCIGLQAGSNKGASQTGMSMGAVRHIADIRC---------DEMSDEAKGVIGLQAGSNKGAT 474
            IG  RF +  V+   E    +  EG+  I  QAG    ASQ G +SMG  R+ +A IR     D    GV+  Q G+N  A+Q GM     +G  R       GLE+ ++    G       +G NK A+Q G   G    + D+           +E+  +++G++ LQ+G+NK A+
Sbjct:   91 IGASRFQVPKVTYKKEWETILDKEGEKIIPKQAGDYGLASQAGEVSMGGHRNQVALIRGRLPHDRRTHGVLCFQNGTNLFASQTGMSAPPGLGAVRQATQKIEGLELGEDILRRGTEFTPWYSGQNKFATQAGS--GGFLKVRDVLPHTVGGKDIEEELKQKSEGIVPLQSGTNKLAS 266

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BLAST of Calponin vs. Ensembl Zebrafish
Match: cnn1b (calponin 1, basic, smooth muscle, b [Source:ZFIN;Acc:ZDB-GENE-091118-54])

HSP 1 Score: 78.9518 bits (193), Expect = 8.210e-18
Identity = 52/117 (44.44%), Postives = 69/117 (58.97%), Query Frame = 1

Query:   58 EMSDEGKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIAD 399
            E   EG+  IGLQ G+NK ASQ GM S G  RH+ D +    +   +  I LQ G+NKGA+QAGM   G +R I +    +EM D   + + LQ G+NK ASQTGM++ G  R + D
Sbjct:  156 EKLKEGRNIIGLQMGTNKFASQKGMTSYGTRRHLYDPKTGMENPLDQSTISLQMGTNKGASQAGMTAPGTKRQIFEKKLDMEMCD--TSIVSLQMGTNKVASQTGMTVYGLPRQVYD 270

HSP 2 Score: 49.2914 bits (116), Expect = 3.769e-7
Identity = 28/61 (45.90%), Postives = 36/61 (59.02%), Query Frame = 1

Query:  295 EMSDEGKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            E   EG+  IGLQ G+NK ASQ GM S G  RH+ D +    +   +  I LQ G+NKGA+
Sbjct:  156 EKLKEGRNIIGLQMGTNKFASQKGMTSYGTRRHLYDPKTGMENPLDQSTISLQMGTNKGAS 216

[Close]

BLAST of Calponin vs. Ensembl Zebrafish
Match: cnn3a (calponin 3, acidic a [Source:ZFIN;Acc:ZDB-GENE-030131-5130])

HSP 1 Score: 74.3294 bits (181), Expect = 5.267e-16
Identity = 49/114 (42.98%), Postives = 66/114 (57.89%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIR 405
            G+  IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D  + L+  D   + I LQ G+NK ASQ GMS+  + R + D +
Sbjct:  160 GQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTEKPYDQTTISLQMGTNKGASQAGMSAPGTRRDIYDQKAALQPMDN--STISLQMGTNKVASQKGMSVYGLGRQVYDPK 271

HSP 2 Score: 60.077 bits (144), Expect = 6.566e-11
Identity = 54/152 (35.53%), Postives = 78/152 (51.32%), Query Frame = 1

Query:   37 NDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEA----KGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            ND+     M+    T + L + +     +T + +G V++ AD +     DE     + VIGLQ G+NK A+QAGM   G +R + D  +  E   + +T I LQ G+NKGASQ GMS  G  R I D +   +       I LQ G+NK A+
Sbjct:  107 NDLFENGNMTQVQTTLLALASMAKTKGMETNIDIG-VKY-ADKQQRNFDDEKMKAGQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTEKPYD-QTTISLQMGTNKGASQAGMSAPGTRRDIYDQKA-ALQPMDNSTISLQMGTNKVAS 254

[Close]

BLAST of Calponin vs. Ensembl Zebrafish
Match: cnn2 (calponin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-542])

HSP 1 Score: 71.633 bits (174), Expect = 4.037e-15
Identity = 46/113 (40.71%), Postives = 65/113 (57.52%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIR 405
            G+  IGLQ G+NK ASQ GM + G  RH+ D +   +       I LQ G+NKGA+QAGM   G +R I D  +G +  D   + + LQ G ++GA+Q+G + G  R I D +
Sbjct:  161 GQCVIGLQMGTNKCASQAGMNAYGTRRHLYDPKSHILPPMDHSTISLQMGTNKGASQAGMTAPGTRRAIYDQKTGTDKCDN--STMSLQMGYSQGANQSGQNFGLGRQIYDAK 271

HSP 2 Score: 52.373 bits (124), Expect = 3.128e-8
Identity = 42/107 (39.25%), Postives = 56/107 (52.34%), Query Frame = 1

Query:  172 DEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGA 471
            DE     + VIGLQ G+NK A+QAGM   G +R + D  S + +     + I LQ G+NKGASQ GM+  G  R I D      +CD         + LQ G ++GA
Sbjct:  155 DEKMKAGQCVIGLQMGTNKCASQAGMNAYGTRRHLYDPKSHI-LPPMDHSTISLQMGTNKGASQAGMTAPGTRRAIYDQKTGTDKCDN------STMSLQMGYSQGA 254

HSP 3 Score: 45.4394 bits (106), Expect = 6.360e-6
Identity = 25/56 (44.64%), Postives = 33/56 (58.93%), Query Frame = 1

Query:  310 GKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            G+  IGLQ G+NK ASQ GM + G  RH+ D +   +       I LQ G+NKGA+
Sbjct:  161 GQCVIGLQMGTNKCASQAGMNAYGTRRHLYDPKSHILPPMDHSTISLQMGTNKGAS 216

[Close]

BLAST of Calponin vs. Ensembl Zebrafish
Match: cnn3b (calponin 3, acidic b [Source:ZFIN;Acc:ZDB-GENE-050522-263])

HSP 1 Score: 70.0922 bits (170), Expect = 1.632e-14
Identity = 48/114 (42.11%), Postives = 65/114 (57.02%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIR 405
            G+  IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D    ++  D   + I LQ G+NK ASQ GMS+  + R + D +
Sbjct:  160 GQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQADKPFDQTTISLQMGTNKGASQAGMSAPGTRRDIFDQKVAVQPLDN--STISLQMGTNKVASQKGMSVYGLGRQVYDPK 271

HSP 2 Score: 55.8398 bits (133), Expect = 2.186e-9
Identity = 41/94 (43.62%), Postives = 54/94 (57.45%), Query Frame = 1

Query:  199 VIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            VIGLQ G+NK A+QAGM   G +R + D  +  +   + +T I LQ G+NKGASQ GMS  G  R I D +   +       I LQ G+NK A+
Sbjct:  163 VIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQADKPFD-QTTISLQMGTNKGASQAGMSAPGTRRDIFDQKV-AVQPLDNSTISLQMGTNKVAS 254

[Close]

BLAST of Calponin vs. Ensembl Zebrafish
Match: cnn3b (calponin 3, acidic b [Source:ZFIN;Acc:ZDB-GENE-050522-263])

HSP 1 Score: 69.707 bits (169), Expect = 1.798e-14
Identity = 48/114 (42.11%), Postives = 65/114 (57.02%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIR 405
            G+  IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D    ++  D   + I LQ G+NK ASQ GMS+  + R + D +
Sbjct:  119 GQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQADKPFDQTTISLQMGTNKGASQAGMSAPGTRRDIFDQKVAVQPLDN--STISLQMGTNKVASQKGMSVYGLGRQVYDPK 230

HSP 2 Score: 55.4546 bits (132), Expect = 2.296e-9
Identity = 43/103 (41.75%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  172 DEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            DE     + VIGLQ G+NK A+QAGM   G +R + D  +  +   + +T I LQ G+NKGASQ GMS  G  R I D +   +       I LQ G+NK A+
Sbjct:  113 DEKMKAGQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQADKPFD-QTTISLQMGTNKGASQAGMSAPGTRRDIFDQKV-AVQPLDNSTISLQMGTNKVAS 213

[Close]

BLAST of Calponin vs. Ensembl Xenopus
Match: slc5a8.1 (solute carrier family 5 member 8, gene 1 [Source:Xenbase;Acc:XB-GENE-479634])

HSP 1 Score: 82.4185 bits (202), Expect = 6.173e-19
Identity = 57/120 (47.50%), Postives = 72/120 (60.00%), Query Frame = 1

Query:   55 LEMSDEGKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIAD 399
            L+   EG+  IGLQ G+NK ASQ GM S G  RH+ D +   D+  D+A   I LQ G+NKGA+Q+GM   G +R I D   G+E  D     I LQ GSNKGASQ GM++ G  R + D
Sbjct:  153 LDKLKEGRNIIGLQMGTNKYASQKGMTSYGTRRHLYDPKLANDQPLDQA--TISLQMGTNKGASQSGMTAPGTKRQIFDQKLGMEHCD--TQTISLQMGSNKGASQQGMTVYGLPRQVYD 268

HSP 2 Score: 57.7658 bits (138), Expect = 4.490e-10
Identity = 43/103 (41.75%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIR-----CDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D     +   +  T I LQ G+NKGASQ+GM+  G  R I D +     CD  +      I LQ GSNKGA+
Sbjct:  158 EGRNIIGLQMGTNKYASQKGMTSYGTRRHLYDPKLANDQPLDQAT-ISLQMGTNKGASQSGMTAPGTKRQIFDQKLGMEHCDTQT------ISLQMGSNKGAS 253

HSP 3 Score: 51.2174 bits (121), Expect = 1.078e-7
Identity = 31/64 (48.44%), Postives = 40/64 (62.50%), Query Frame = 1

Query:  292 LEMSDEGKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGAT 474
            L+   EG+  IGLQ G+NK ASQ GM S G  RH+ D +   D+  D+A   I LQ G+NKGA+
Sbjct:  153 LDKLKEGRNIIGLQMGTNKYASQKGMTSYGTRRHLYDPKLANDQPLDQA--TISLQMGTNKGAS 214

[Close]

BLAST of Calponin vs. Ensembl Xenopus
Match: tfdp1 (transcription factor Dp-1 [Source:Xenbase;Acc:XB-GENE-1219073])

HSP 1 Score: 73.1738 bits (178), Expect = 1.003e-15
Identity = 49/115 (42.61%), Postives = 67/115 (58.26%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIRC 408
            G++ IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D  + L+  D   + I LQ G+NK ASQ GMS+  + R + D + 
Sbjct:   95 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMPAPGTRRDIYDQKAILQPVD--NSTISLQMGTNKVASQKGMSVYGLGRQVYDPKY 207

HSP 2 Score: 54.6842 bits (130), Expect = 5.139e-9
Identity = 42/103 (40.78%), Postives = 55/103 (53.40%), Query Frame = 1

Query:  172 DEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            DE     + VIGLQ G+NK A+QAGM   G +R + D     +   + +T I LQ G+NKGASQ GM   G  R I D +   +       I LQ G+NK A+
Sbjct:   89 DEKMKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFD-QTTISLQMGTNKGASQAGMPAPGTRRDIYDQKA-ILQPVDNSTISLQMGTNKVAS 189

[Close]

BLAST of Calponin vs. Ensembl Xenopus
Match: tfdp1 (transcription factor Dp-1 [Source:Xenbase;Acc:XB-GENE-1219073])

HSP 1 Score: 73.1738 bits (178), Expect = 1.728e-15
Identity = 49/115 (42.61%), Postives = 67/115 (58.26%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIRC 408
            G++ IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D  + L+  D   + I LQ G+NK ASQ GMS+  + R + D + 
Sbjct:  160 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMPAPGTRRDIYDQKAILQPVD--NSTISLQMGTNKVASQKGMSVYGLGRQVYDPKY 272

HSP 2 Score: 54.6842 bits (130), Expect = 7.496e-9
Identity = 42/103 (40.78%), Postives = 55/103 (53.40%), Query Frame = 1

Query:  172 DEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            DE     + VIGLQ G+NK A+QAGM   G +R + D     +   + +T I LQ G+NKGASQ GM   G  R I D +   +       I LQ G+NK A+
Sbjct:  154 DEKMKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFD-QTTISLQMGTNKGASQAGMPAPGTRRDIYDQKA-ILQPVDNSTISLQMGTNKVAS 254

[Close]

BLAST of Calponin vs. Ensembl Xenopus
Match: cnn1 (calponin 1, basic, smooth muscle [Source:NCBI gene;Acc:407907])

HSP 1 Score: 71.633 bits (174), Expect = 4.950e-15
Identity = 47/113 (41.59%), Postives = 61/113 (53.98%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIR 405
            G   IGLQ G+NK ASQ+GM+  G  RH+ D +   +       I LQ GSNKGA+Q GM   G +R I D   G E  D   + + LQ G  +GA+Q+G   G  R I D +
Sbjct:  162 GHCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNTILPPMDHSTISLQMGSNKGASQVGMTAPGTRRHIYDTKLGTEKCD--NSSMSLQMGYTQGANQSGQIFGLGRQIYDPK 272

HSP 2 Score: 46.9802 bits (110), Expect = 3.454e-6
Identity = 26/56 (46.43%), Postives = 33/56 (58.93%), Query Frame = 1

Query:  310 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            G   IGLQ G+NK ASQ+GM+  G  RH+ D +   +       I LQ GSNKGA+
Sbjct:  162 GHCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNTILPPMDHSTISLQMGSNKGAS 217

[Close]

BLAST of Calponin vs. Ensembl Mouse
Match: Cnn1 (calponin 1 [Source:MGI Symbol;Acc:MGI:104979])

HSP 1 Score: 78.9518 bits (193), Expect = 4.104e-18
Identity = 54/117 (46.15%), Postives = 71/117 (60.68%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIR 405
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D +
Sbjct:  109 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPK 221

HSP 2 Score: 58.5362 bits (140), Expect = 1.506e-10
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  109 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 204

[Close]

BLAST of Calponin vs. Ensembl Mouse
Match: Cnn1 (calponin 1 [Source:MGI Symbol;Acc:MGI:104979])

HSP 1 Score: 79.337 bits (194), Expect = 6.591e-18
Identity = 54/118 (45.76%), Postives = 71/118 (60.17%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIRC 408
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D + 
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKY 272

HSP 2 Score: 58.9214 bits (141), Expect = 1.763e-10
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 254

[Close]

BLAST of Calponin vs. Ensembl Mouse
Match: Cnn3 (calponin 3, acidic [Source:MGI Symbol;Acc:MGI:1919244])

HSP 1 Score: 72.4034 bits (176), Expect = 1.685e-15
Identity = 51/117 (43.59%), Postives = 70/117 (59.83%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIAD--IRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIRC 408
            G++ IGLQ G+NK ASQ GM+  G  RH+ D  ++ D+  D+    I LQ G+NKGA+QAGM   G +R I D    L+  D   + I LQ G+NK ASQ GMS+  + R + D + 
Sbjct:  114 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQT--TISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVD--NSTISLQMGTNKVASQKGMSVYGLGRQVYDPKY 226

HSP 2 Score: 45.8246 bits (107), Expect = 6.049e-6
Identity = 27/58 (46.55%), Postives = 38/58 (65.52%), Query Frame = 1

Query:  310 GKTCIGLQAGSNKGASQTGMS-MGAVRHIAD--IRCDEMSDEAKGVIGLQAGSNKGAT 474
            G++ IGLQ G+NK ASQ GM+  G  RH+ D  ++ D+  D+    I LQ G+NKGA+
Sbjct:  114 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQT--TISLQMGTNKGAS 169

[Close]

BLAST of Calponin vs. Ensembl Mouse
Match: Cnn3 (calponin 3, acidic [Source:MGI Symbol;Acc:MGI:1919244])

HSP 1 Score: 72.7886 bits (177), Expect = 2.343e-15
Identity = 49/115 (42.61%), Postives = 66/115 (57.39%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIRC 408
            G++ IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D    L+  D   + I LQ G+NK ASQ GMS+  + R + D + 
Sbjct:  160 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVD--NSTISLQMGTNKVASQKGMSVYGLGRQVYDPKY 272

HSP 2 Score: 45.8246 bits (107), Expect = 6.371e-6
Identity = 25/56 (44.64%), Postives = 34/56 (60.71%), Query Frame = 1

Query:  310 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            G++ IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+
Sbjct:  160 GQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGAS 215

[Close]

BLAST of Calponin vs. Ensembl Mouse
Match: Cnn2 (calponin 2 [Source:MGI Symbol;Acc:MGI:105093])

HSP 1 Score: 66.6254 bits (161), Expect = 3.233e-13
Identity = 44/113 (38.94%), Postives = 61/113 (53.98%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIR 405
            G+  IGLQ G+NK ASQ+GM+  G  RH+ D +   +       I LQ G+NK A+Q GM   G +R I D   G +  D   + + LQ G  +GA+Q+G   G  R I D +
Sbjct:  162 GQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHCTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDN--SSMSLQMGYTQGANQSGQVFGLGRQIYDPK 272

[Close]

BLAST of Calponin vs. UniProt/SwissProt
Match: sp|P26932|CNN1_CHICK (Calponin-1 OS=Gallus gallus OX=9031 GN=CNN1 PE=1 SV=2)

HSP 1 Score: 87.4261 bits (215), Expect = 4.730e-20
Identity = 62/131 (47.33%), Postives = 80/131 (61.07%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIR-CDEMSDEAKGVIG 444
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I + S G+E  D     IGLQ GSNKGASQ GM++ G  R + D + CD     A G++G
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPSLGMERCDT--NIIGLQMGSNKGASQQGMTVYGLPRQVYDPKYCD-----APGLLG 280

HSP 2 Score: 63.1586 bits (152), Expect = 3.549e-11
Identity = 52/153 (33.99%), Postives = 72/153 (47.06%), Query Frame = 1

Query:   37 NDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            ND+      +    T I L + +    +  G+ +            E   E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +      RCD        +IGLQ GSNKGA+
Sbjct:  109 NDLFENTNHTQVQSTLIALASQAKTKGNNVGLGVKYAEKQQRRFQPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPSLGMERCDT------NIIGLQMGSNKGAS 254

[Close]

BLAST of Calponin vs. UniProt/SwissProt
Match: sp|Q7YRL2|CNN1_SHEEP (Calponin-1 OS=Ovis aries OX=9940 GN=CNN1 PE=2 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 4.425e-17
Identity = 54/118 (45.76%), Postives = 71/118 (60.17%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIRC 408
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D + 
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKY 272

HSP 2 Score: 58.5362 bits (140), Expect = 1.308e-9
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 254

[Close]

BLAST of Calponin vs. UniProt/SwissProt
Match: sp|Q08092|CNN1_PIG (Calponin-1 OS=Sus scrofa OX=9823 GN=CNN1 PE=2 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 4.471e-17
Identity = 54/118 (45.76%), Postives = 71/118 (60.17%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIRC 408
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D + 
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKY 272

HSP 2 Score: 58.5362 bits (140), Expect = 1.308e-9
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 254

[Close]

BLAST of Calponin vs. UniProt/SwissProt
Match: sp|Q08091|CNN1_MOUSE (Calponin-1 OS=Mus musculus OX=10090 GN=Cnn1 PE=1 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 4.610e-17
Identity = 54/118 (45.76%), Postives = 71/118 (60.17%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIRC 408
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D + 
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKY 272

HSP 2 Score: 58.9214 bits (141), Expect = 1.233e-9
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 254

[Close]

BLAST of Calponin vs. UniProt/SwissProt
Match: sp|Q2HJ38|CNN1_BOVIN (Calponin-1 OS=Bos taurus OX=9913 GN=CNN1 PE=2 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 4.658e-17
Identity = 54/118 (45.76%), Postives = 71/118 (60.17%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIADIRC 408
            EG+  IGLQ G+NK ASQ GM+  G  RH+ D +   D+  D+A   I LQ G+NKGA+QAGM   G +R I +   G+E  D     + LQ GSNKGASQ GM++ G  R + D + 
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQA--TISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCD--TLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKY 272

HSP 2 Score: 58.5362 bits (140), Expect = 1.388e-9
Identity = 42/103 (40.78%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  187 EAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADI-----RCDEMSDEAKGVIGLQAGSNKGAT 474
            E + +IGLQ G+NK A+Q GM   G +R + D   G +   +  T I LQ G+NKGASQ GM+  G  R I +       CD ++      + LQ GSNKGA+
Sbjct:  159 EGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQAT-ISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLN------VSLQMGSNKGAS 254

[Close]

BLAST of Calponin vs. TrEMBL
Match: A0A0R3S938 (Transgelin OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS727 PE=3 SV=1)

HSP 1 Score: 192.971 bits (489), Expect = 8.446e-57
Identity = 104/158 (65.82%), Postives = 126/158 (79.75%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q+GM +G  R I D   G EMSD GK+ IGLQAGSNKGASQ+GMSMGAVRHIADIR D+MS E + VIGLQAGSNKGATQ+GM +G  R I D+    E+S EG++ IGLQAG+N+ A+Q+GMSMG VRHIADI+ D+MS E  G+IGLQ+GSN+GA+
Sbjct:  261 QSGMAMGAMRHIADQKIG-EMSDAGKSTIGLQAGSNKGASQSGMSMGAVRHIADIRVDKMSKEGESVIGLQAGSNKGATQSGMAMGAVRHIADIKVD-EISKEGQSVIGLQAGTNQYANQSGMSMGGVRHIADIKVDDMSKEGAGIIGLQSGSNQGAS 416

HSP 2 Score: 182.57 bits (462), Expect = 9.560e-53
Identity = 102/158 (64.56%), Postives = 119/158 (75.32%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q GM +G  R I D+ +  +MS E    IGLQAGSNKGA+Q+GM+MGA+RHIAD    EMSD  K  + LQ G+NKGA+Q+GM +G  R I D   G EMSD GK+ IGLQAGSNKGASQ+GMSMGAVRHIADIR D+MS E + VIGLQAGSNKGAT
Sbjct:  183 QKGMSMGAVRHIADIKAD-DMSRESHGIIGLQAGSNKGANQSGMAMGAIRHIADQNIGEMSDTGKTSLNLQMGTNKGASQSGMAMGAMRHIADQKIG-EMSDAGKSTIGLQAGSNKGASQSGMSMGAVRHIADIRVDKMSKEGESVIGLQAGSNKGAT 338

HSP 3 Score: 179.874 bits (455), Expect = 1.003e-51
Identity = 98/157 (62.42%), Postives = 122/157 (77.71%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGA 471
            Q+GM +G  R I D + G EMSD GKT + LQ G+NKGASQ+GM+MGA+RHIAD +  EMSD  K  IGLQAGSNKGA+Q+GM +G  R I D+    +MS EG++ IGLQAGSNKGA+Q+GM+MGAVRHIADI+ DE+S E + VIGLQAG+N+ A
Sbjct:  222 QSGMAMGAIRHIADQNIG-EMSDTGKTSLNLQMGTNKGASQSGMAMGAMRHIADQKIGEMSDAGKSTIGLQAGSNKGASQSGMSMGAVRHIADIRVD-KMSKEGESVIGLQAGSNKGATQSGMAMGAVRHIADIKVDEISKEGQSVIGLQAGTNQYA 376

HSP 4 Score: 149.058 bits (375), Expect = 5.418e-40
Identity = 81/138 (58.70%), Postives = 103/138 (74.64%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDE 414
            Q+GM +G  R I D+    +MS EG++ IGLQAGSNKGA+Q+GM+MGAVRHIADI+ DE+S E + VIGLQAG+N+ A Q+GM +GG R I D+    +MS EG   IGLQ+GSN+GASQ GMS GA RHI D++  E
Sbjct:  300 QSGMSMGAVRHIADIRVD-KMSKEGESVIGLQAGSNKGATQSGMAMGAVRHIADIKVDEISKEGQSVIGLQAGTNQYANQSGMSMGGVRHIADIKVD-DMSKEGAGIIGLQSGSNQGASQAGMSFGAQRHITDVQVGE 435

HSP 5 Score: 103.99 bits (258), Expect = 4.160e-23
Identity = 57/97 (58.76%), Postives = 71/97 (73.20%), Query Frame = 1

Query:  184 DEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            + +K VIGLQAGSNKGA+Q GM +G  R I D+ +  +MS E    IGLQAGSNKGA+Q+GM+MGA+RHIAD    EMSD  K  + LQ G+NKGA+
Sbjct:  165 NASKAVIGLQAGSNKGASQKGMSMGAVRHIADIKAD-DMSRESHGIIGLQAGSNKGANQSGMAMGAIRHIADQNIGEMSDTGKTSLNLQMGTNKGAS 260

[Close]

BLAST of Calponin vs. TrEMBL
Match: A0A564YRY7 (Transgelin OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS8406 PE=3 SV=1)

HSP 1 Score: 192.971 bits (489), Expect = 1.077e-56
Identity = 104/158 (65.82%), Postives = 126/158 (79.75%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q+GM +G  R I D   G EMSD GK+ IGLQAGSNKGASQ+GMSMGAVRHIADIR D+MS E + VIGLQAGSNKGATQ+GM +G  R I D+    E+S EG++ IGLQAG+N+ A+Q+GMSMG VRHIADI+ D+MS E  G+IGLQ+GSN+GA+
Sbjct:  266 QSGMAMGAMRHIADQKIG-EMSDAGKSTIGLQAGSNKGASQSGMSMGAVRHIADIRVDKMSKEGESVIGLQAGSNKGATQSGMAMGAVRHIADIKVD-EISKEGQSVIGLQAGTNQYANQSGMSMGGVRHIADIKVDDMSKEGAGIIGLQSGSNQGAS 421

HSP 2 Score: 182.57 bits (462), Expect = 1.174e-52
Identity = 102/158 (64.56%), Postives = 119/158 (75.32%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q GM +G  R I D+ +  +MS E    IGLQAGSNKGA+Q+GM+MGA+RHIAD    EMSD  K  + LQ G+NKGA+Q+GM +G  R I D   G EMSD GK+ IGLQAGSNKGASQ+GMSMGAVRHIADIR D+MS E + VIGLQAGSNKGAT
Sbjct:  188 QKGMSMGAVRHIADIKAD-DMSRESHGIIGLQAGSNKGANQSGMAMGAIRHIADQNIGEMSDTGKTSLNLQMGTNKGASQSGMAMGAMRHIADQKIG-EMSDAGKSTIGLQAGSNKGASQSGMSMGAVRHIADIRVDKMSKEGESVIGLQAGSNKGAT 343

HSP 3 Score: 179.874 bits (455), Expect = 1.296e-51
Identity = 98/157 (62.42%), Postives = 122/157 (77.71%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGA 471
            Q+GM +G  R I D + G EMSD GKT + LQ G+NKGASQ+GM+MGA+RHIAD +  EMSD  K  IGLQAGSNKGA+Q+GM +G  R I D+    +MS EG++ IGLQAGSNKGA+Q+GM+MGAVRHIADI+ DE+S E + VIGLQAG+N+ A
Sbjct:  227 QSGMAMGAIRHIADQNIG-EMSDTGKTSLNLQMGTNKGASQSGMAMGAMRHIADQKIGEMSDAGKSTIGLQAGSNKGASQSGMSMGAVRHIADIRVD-KMSKEGESVIGLQAGSNKGATQSGMAMGAVRHIADIKVDEISKEGQSVIGLQAGTNQYA 381

HSP 4 Score: 149.058 bits (375), Expect = 6.774e-40
Identity = 81/138 (58.70%), Postives = 103/138 (74.64%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDE 414
            Q+GM +G  R I D+    +MS EG++ IGLQAGSNKGA+Q+GM+MGAVRHIADI+ DE+S E + VIGLQAG+N+ A Q+GM +GG R I D+    +MS EG   IGLQ+GSN+GASQ GMS GA RHI D++  E
Sbjct:  305 QSGMSMGAVRHIADIRVD-KMSKEGESVIGLQAGSNKGATQSGMAMGAVRHIADIKVDEISKEGQSVIGLQAGTNQYANQSGMSMGGVRHIADIKVD-DMSKEGAGIIGLQSGSNQGASQAGMSFGAQRHITDVQVGE 440

HSP 5 Score: 103.99 bits (258), Expect = 4.463e-23
Identity = 57/95 (60.00%), Postives = 70/95 (73.68%), Query Frame = 1

Query:  190 AKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            +K VIGLQAGSNKGA+Q GM +G  R I D+ +  +MS E    IGLQAGSNKGA+Q+GM+MGA+RHIAD    EMSD  K  + LQ G+NKGA+
Sbjct:  172 SKAVIGLQAGSNKGASQKGMSMGAVRHIADIKAD-DMSRESHGIIGLQAGSNKGANQSGMAMGAIRHIADQNIGEMSDTGKTSLNLQMGTNKGAS 265

[Close]

BLAST of Calponin vs. TrEMBL
Match: A0A3G1GHW9 (Transgelin (Fragment) OS=Crenomytilus grayanus OX=151218 PE=2 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 8.409e-56
Identity = 97/158 (61.39%), Postives = 123/158 (77.85%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            QAGMR+G  R I+D+ +  +MS EG+  IGLQ+G+NK ASQ GM MGA RHI+DIR D+M+ E +GVIGLQ+GSNK A+QAGMR+G  R I+D+ +  +M+ EG+  IGLQ GSNKGASQ GMS GA RH++DIR ++MS E  GVIGLQ GSNKGA+
Sbjct:  120 QAGMRMGASRHISDIKAE-DMSQEGQGIIGLQSGTNKYASQAGMRMGASRHISDIRADDMTQEGQGVIGLQSGSNKFASQAGMRMGASRHISDIRAD-DMTQEGQGVIGLQYGSNKGASQKGMSFGAPRHVSDIRVEDMSQEGHGVIGLQYGSNKGAS 275

HSP 2 Score: 162.54 bits (410), Expect = 1.602e-46
Identity = 85/144 (59.03%), Postives = 111/144 (77.08%), Query Frame = 1

Query:   55 LEMSDE----GKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            +  +DE    G+  IGLQAG+NK ASQ GM MGA RHI+DI+ ++MS E +G+IGLQ+G+NK A+QAGMR+G  R I+D+ +  +M+ EG+  IGLQ+GSNK ASQ GM MGA RHI+DIR D+M+ E +GVIGLQ GSNKGA+
Sbjct:   94 VNFTDEQLKAGQGIIGLQAGTNKCASQAGMRMGASRHISDIKAEDMSQEGQGIIGLQSGTNKYASQAGMRMGASRHISDIRAD-DMTQEGQGVIGLQSGSNKFASQAGMRMGASRHISDIRADDMTQEGQGVIGLQYGSNKGAS 236

HSP 3 Score: 156.762 bits (395), Expect = 3.191e-44
Identity = 83/136 (61.03%), Postives = 100/136 (73.53%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRC 408
            QAGMR+G  R I+D+ +  +M+ EG+  IGLQ+GSNK ASQ GM MGA RHI+DIR D+M+ E +GVIGLQ GSNKGA+Q GM  G  R ++D+    +MS EG   IGLQ GSNKGASQ GMS GA RHIADIR 
Sbjct:  159 QAGMRMGASRHISDIRAD-DMTQEGQGVIGLQSGSNKFASQAGMRMGASRHISDIRADDMTQEGQGVIGLQYGSNKGASQKGMSFGAPRHVSDIRVE-DMSQEGHGVIGLQYGSNKGASQKGMSFGATRHIADIRA 292

HSP 4 Score: 118.242 bits (295), Expect = 2.632e-29
Identity = 65/119 (54.62%), Postives = 87/119 (73.11%), Query Frame = 1

Query:  127 GMSMG---AVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            GM++G     +HI +   DE     +G+IGLQAG+NK A+QAGMR+G  R I+D+ +  +MS EG+  IGLQ+G+NK ASQ GM MGA RHI+DIR D+M+ E +GVIGLQ+GSNK A+
Sbjct:   81 GMTIGKKPTEKHIVNF-TDEQLKAGQGIIGLQAGTNKCASQAGMRMGASRHISDIKAE-DMSQEGQGIIGLQSGTNKYASQAGMRMGASRHISDIRADDMTQEGQGVIGLQSGSNKFAS 197

[Close]

BLAST of Calponin vs. TrEMBL
Match: R7UJ28 (Transgelin OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_17776 PE=3 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 4.670e-55
Identity = 99/158 (62.66%), Postives = 128/158 (81.01%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q+GM +GG R I D+ +  ++  EG   IGLQ+GSNKGASQ+GMSMGAVRH++DIR DEM  + +GVIGLQAGSNKGA+QAGM +G  R ++D+ +  EM  +G+  IGLQAGSNKGASQ+GM+MG+VRH++DIR D+MS + +GVIGLQAGSNKGA+
Sbjct:  185 QSGMAMGGVRHIADIKAD-DLCREGTGVIGLQSGSNKGASQSGMSMGAVRHVSDIRADEMDKDGQGVIGLQAGSNKGASQAGMSMGAVRHVSDIRAD-EMDKDGQGVIGLQAGSNKGASQSGMAMGSVRHVSDIRADDMSKDGQGVIGLQAGSNKGAS 340

HSP 2 Score: 181.03 bits (458), Expect = 3.747e-52
Identity = 96/158 (60.76%), Postives = 126/158 (79.75%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q+GM +G  R ++D+ +  EM  +G+  IGLQAGSNKGASQ GMSMGAVRH++DIR DEM  + +GVIGLQAGSNKGA+Q+GM +G  R ++D+ +  +MS +G+  IGLQAGSNKGASQ+GMSMG+VRH++DI+  + S E + +IGLQAGSNKGAT
Sbjct:  224 QSGMSMGAVRHVSDIRAD-EMDKDGQGVIGLQAGSNKGASQAGMSMGAVRHVSDIRADEMDKDGQGVIGLQAGSNKGASQSGMAMGSVRHVSDIRAD-DMSKDGQGVIGLQAGSNKGASQSGMSMGSVRHVSDIKSGQGSAEGQAIIGLQAGSNKGAT 379

HSP 3 Score: 168.318 bits (425), Expect = 2.649e-47
Identity = 87/134 (64.93%), Postives = 108/134 (80.60%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            G   IGLQAG+NK ASQ+GM+MG VRHIADI+ D++  E  GVIGLQ+GSNKGA+Q+GM +G  R ++D+ +  EM  +G+  IGLQAGSNKGASQ GMSMGAVRH++DIR DEM  + +GVIGLQAGSNKGA+
Sbjct:  169 GNAIIGLQAGTNKCASQSGMAMGGVRHIADIKADDLCREGTGVIGLQSGSNKGASQSGMSMGAVRHVSDIRAD-EMDKDGQGVIGLQAGSNKGASQAGMSMGAVRHVSDIRADEMDKDGQGVIGLQAGSNKGAS 301

HSP 4 Score: 166.777 bits (421), Expect = 1.102e-46
Identity = 90/158 (56.96%), Postives = 121/158 (76.58%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            QAGM +G  R ++D+ +  EM  +G+  IGLQAGSNKGASQ+GM+MG+VRH++DIR D+MS + +GVIGLQAGSNKGA+Q+GM +G  R ++D+ SG + S EG+  IGLQAGSNKGA+Q+GMSMGA R ++DI+  +M   + GV  LQ GS  GA+
Sbjct:  263 QAGMSMGAVRHVSDIRAD-EMDKDGQGVIGLQAGSNKGASQSGMAMGSVRHVSDIRADDMSKDGQGVIGLQAGSNKGASQSGMSMGSVRHVSDIKSG-QGSAEGQAIIGLQAGSNKGATQSGMSMGANRMVSDIKTGKMDQSSHGVTSLQYGSTDGAS 418

HSP 5 Score: 86.2705 bits (212), Expect = 1.211e-16
Identity = 48/92 (52.17%), Postives = 65/92 (70.65%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFIN 276
            Q+GM +G  R ++D+ SG + S EG+  IGLQAGSNKGA+Q+GMSMGA R ++DI+  +M   + GV  LQ GS  GA+Q+GM  GG R I+
Sbjct:  341 QSGMSMGSVRHVSDIKSG-QGSAEGQAIIGLQAGSNKGATQSGMSMGANRMVSDIKTGKMDQSSHGVTSLQYGSTDGASQSGMSFGGARNIS 431

[Close]

BLAST of Calponin vs. TrEMBL
Match: A0A183SYR3 (Transgelin OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS9361 PE=3 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 5.790e-55
Identity = 99/139 (71.22%), Postives = 112/139 (80.58%), Query Frame = 1

Query:   58 EMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            E  +  KT IGLQAGSNKGASQ+GMSMGA RHIADI+ DEMS EAKGVIGLQ+GSNKGA+Q+GM +G  R I D+    EMS+ GKT IGL +G+NKGASQ+GMSMGAVRHIAD R  EMS E K  IGLQAGSN+GAT
Sbjct:  150 EQLNASKTIIGLQAGSNKGASQSGMSMGATRHIADIKVDEMSAEAKGVIGLQSGSNKGASQSGMSMGATRHIADLKVD-EMSEAGKTSIGLLSGTNKGASQSGMSMGAVRHIADTRVGEMSAEGKSTIGLQAGSNQGAT 287

HSP 2 Score: 181.03 bits (458), Expect = 3.740e-53
Identity = 98/158 (62.03%), Postives = 120/158 (75.95%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q+GM +G  R I D+    EMS E K  IGLQ+GSNKGASQ+GMSMGA RHIAD++ DEMS+  K  IGL +G+NKGA+Q+GM +G  R I D   G EMS EGK+ IGLQAGSN+GA+Q+GM+MG VRHIADI+ ++MS E   VIGLQAGSN GA+
Sbjct:  171 QSGMSMGATRHIADIKVD-EMSAEAKGVIGLQSGSNKGASQSGMSMGATRHIADLKVDEMSEAGKTSIGLLSGTNKGASQSGMSMGAVRHIADTRVG-EMSAEGKSTIGLQAGSNQGATQSGMTMGGVRHIADIKVEDMSKEGASVIGLQAGSNLGAS 326

HSP 3 Score: 154.836 bits (390), Expect = 7.271e-43
Identity = 85/139 (61.15%), Postives = 102/139 (73.38%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEM 417
            Q+GM +G  R I D+    EMS+ GKT IGL +G+NKGASQ+GMSMGAVRHIAD R  EMS E K  IGLQAGSN+GATQ+GM +GG R I D+    +MS EG + IGLQAGSN GASQ GM+ GA RHI D++  E+
Sbjct:  210 QSGMSMGATRHIADLKVD-EMSEAGKTSIGLLSGTNKGASQSGMSMGAVRHIADTRVGEMSAEGKSTIGLQAGSNQGATQSGMTMGGVRHIADIKVE-DMSKEGASVIGLQAGSNLGASQAGMNFGAQRHIGDVKVGEL 346

[Close]

BLAST of Calponin vs. Ensembl Cavefish
Match: cnn1b (calponin 1 [Source:NCBI gene;Acc:103040806])

HSP 1 Score: 74.3294 bits (181), Expect = 4.044e-16
Identity = 50/117 (42.74%), Postives = 66/117 (56.41%), Query Frame = 1

Query:   58 EMSDEGKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSM-GAVRHIAD 399
            E   EG+  IGLQ G+NK ASQ GM S G  RH+ D +    +   +  I LQ G+NKGA Q+GM   G +R I D    +E  D     + LQ G+NK ASQ+GM++ G  R + D
Sbjct:  157 EKLKEGRNIIGLQMGTNKFASQKGMTSYGTRRHLYDPKVGMENPLDQSTISLQMGTNKGANQSGMTAPGTKRQIFDKKLDMESCDTA--TVSLQMGTNKVASQSGMTVYGLPRQVYD 271

HSP 2 Score: 48.9062 bits (115), Expect = 3.465e-7
Identity = 28/60 (46.67%), Postives = 35/60 (58.33%), Query Frame = 1

Query:  295 EMSDEGKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGA 471
            E   EG+  IGLQ G+NK ASQ GM S G  RH+ D +    +   +  I LQ G+NKGA
Sbjct:  157 EKLKEGRNIIGLQMGTNKFASQKGMTSYGTRRHLYDPKVGMENPLDQSTISLQMGTNKGA 216

[Close]

BLAST of Calponin vs. Ensembl Cavefish
Match: ENSAMXT00000037688.1 (calponin-3-like [Source:NCBI gene;Acc:103046041])

HSP 1 Score: 71.2478 bits (173), Expect = 5.294e-15
Identity = 57/146 (39.04%), Postives = 74/146 (50.68%), Query Frame = 1

Query:   25 QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIR-CDEMSDEAKGVIGLQ 450
            +R  ND     E    G   IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D     +  D   + I LQ G+NK ASQ GMS+  + R I D + C   ++ A    G Q
Sbjct:  149 ERSFND-----EKMKAGHCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPYDQTTISLQMGTNKGASQAGMSAPGTRRDIFDQKVAQQPMD--NSTISLQMGTNKTASQKGMSVYGLGRQIYDPKYCSSPTEPAPHSNGSQ 287

HSP 2 Score: 45.4394 bits (106), Expect = 6.984e-6
Identity = 29/72 (40.28%), Postives = 37/72 (51.39%), Query Frame = 1

Query:  262 QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            +R  ND     E    G   IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+
Sbjct:  149 ERSFND-----EKMKAGHCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPYDQTTISLQMGTNKGAS 215

[Close]

BLAST of Calponin vs. Ensembl Cavefish
Match: ENSAMXT00000006562.2 (calponin-3-like [Source:NCBI gene;Acc:103046041])

HSP 1 Score: 71.2478 bits (173), Expect = 6.603e-15
Identity = 53/130 (40.77%), Postives = 69/130 (53.08%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIR-CDEMSDEAKGVIGLQ 450
            G   IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D     +  D   + I LQ G+NK ASQ GMS+  + R I D + C   ++ A    G Q
Sbjct:  157 GHCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPYDQTTISLQMGTNKGASQAGMSAPGTRRDIFDQKVAQQPMD--NSTISLQMGTNKTASQKGMSVYGLGRQIYDPKYCSSPTEPAPHSNGSQ 284

HSP 2 Score: 45.4394 bits (106), Expect = 7.439e-6
Identity = 25/56 (44.64%), Postives = 32/56 (57.14%), Query Frame = 1

Query:  310 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            G   IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+
Sbjct:  157 GHCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPYDQTTISLQMGTNKGAS 212

[Close]

BLAST of Calponin vs. Ensembl Cavefish
Match: cnn3a (calponin 3 [Source:NCBI gene;Acc:103024651])

HSP 1 Score: 70.8626 bits (172), Expect = 7.207e-15
Identity = 48/114 (42.11%), Postives = 65/114 (57.02%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIR 405
            G+  IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D    ++  D   + I LQ G+NK ASQ GMS+  + R + D +
Sbjct:  161 GQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPYDQTTISLQMGTNKGASQAGMSAPGTRRDIFDQKVAVQPLD--NSTISLQMGTNKVASQKGMSVYGLGRQVYDPK 272

HSP 2 Score: 56.225 bits (134), Expect = 1.185e-9
Identity = 43/103 (41.75%), Postives = 57/103 (55.34%), Query Frame = 1

Query:  172 DEMSDEAKGVIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            DE     + VIGLQ G+NK A+QAGM   G +R + D  +  +   + +T I LQ G+NKGASQ GMS  G  R I D +   +       I LQ G+NK A+
Sbjct:  155 DEKMKAGQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPYD-QTTISLQMGTNKGASQAGMSAPGTRRDIFDQKV-AVQPLDNSTISLQMGTNKVAS 255

[Close]

BLAST of Calponin vs. Ensembl Cavefish
Match: cnn3a (calponin 3 [Source:NCBI gene;Acc:103024651])

HSP 1 Score: 70.8626 bits (172), Expect = 8.074e-15
Identity = 48/114 (42.11%), Postives = 65/114 (57.02%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIR 405
            G+  IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D    ++  D   + I LQ G+NK ASQ GMS+  + R + D +
Sbjct:  160 GQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPYDQTTISLQMGTNKGASQAGMSAPGTRRDIFDQKVAVQPLD--NSTISLQMGTNKVASQKGMSVYGLGRQVYDPK 271

HSP 2 Score: 55.8398 bits (133), Expect = 1.463e-9
Identity = 41/94 (43.62%), Postives = 54/94 (57.45%), Query Frame = 1

Query:  199 VIGLQAGSNKGATQAGMR-IGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            VIGLQ G+NK A+QAGM   G +R + D  +  +   + +T I LQ G+NKGASQ GMS  G  R I D +   +       I LQ G+NK A+
Sbjct:  163 VIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPYD-QTTISLQMGTNKGASQAGMSAPGTRRDIFDQKV-AVQPLDNSTISLQMGTNKVAS 254

[Close]

BLAST of Calponin vs. Ensembl Medaka
Match: cnn1b (calponin 1 [Source:NCBI gene;Acc:101163085])

HSP 1 Score: 77.7962 bits (190), Expect = 1.827e-17
Identity = 54/115 (46.96%), Postives = 68/115 (59.13%), Query Frame = 1

Query:   70 EGKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGM-SMGAVRHIAD 399
            EG+  IGLQ G+N+ ASQ GM S G  RH+ D +   D   D++   I LQ G+NKGATQAGM   G +R I D    LE+ +   T I LQ G+NK ASQ GM + G  R + D
Sbjct:  160 EGRNIIGLQMGTNQFASQKGMTSYGTRRHLFDAKIGMDNPIDQS--TISLQMGTNKGATQAGMTAPGTRRHIFD--KKLELENCDTTTISLQMGTNKVASQQGMTTYGLPRQVYD 270

HSP 2 Score: 47.7506 bits (112), Expect = 9.801e-7
Identity = 29/59 (49.15%), Postives = 37/59 (62.71%), Query Frame = 1

Query:  307 EGKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRC--DEMSDEAKGVIGLQAGSNKGAT 474
            EG+  IGLQ G+N+ ASQ GM S G  RH+ D +   D   D++   I LQ G+NKGAT
Sbjct:  160 EGRNIIGLQMGTNQFASQKGMTSYGTRRHLFDAKIGMDNPIDQS--TISLQMGTNKGAT 216

[Close]

BLAST of Calponin vs. Ensembl Medaka
Match: cnn3b (calponin 3 [Source:NCBI gene;Acc:101163038])

HSP 1 Score: 72.4034 bits (176), Expect = 3.019e-15
Identity = 49/114 (42.98%), Postives = 65/114 (57.02%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAV-RHIADIR 405
            G+  IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+QAGM   G +R I D    L+  D   + I LQ G+NK ASQ GMS+  + R + D +
Sbjct:  199 GQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPHDQTTISLQMGTNKGASQAGMAAPGTRRDIFDQKVALQPLD--NSTISLQMGTNKVASQRGMSVYGLGRQVYDPK 310

HSP 2 Score: 46.2098 bits (108), Expect = 3.987e-6
Identity = 25/56 (44.64%), Postives = 33/56 (58.93%), Query Frame = 1

Query:  310 GKTCIGLQAGSNKGASQTGMS-MGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            G+  IGLQ G+NK ASQ GM+  G  RH+ D +        +  I LQ G+NKGA+
Sbjct:  199 GQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTDKPHDQTTISLQMGTNKGAS 254

[Close]

BLAST of Calponin vs. Ensembl Medaka
Match: ENSORLT00000007021.2 (calponin 2 [Source:NCBI gene;Acc:101165178])

HSP 1 Score: 68.5514 bits (166), Expect = 5.813e-14
Identity = 46/113 (40.71%), Postives = 63/113 (55.75%), Query Frame = 1

Query:   73 GKTCIGLQAGSNKGASQTGM-SMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGG-QRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIR 405
            G+  IGLQ G+NK ASQ GM + G  RH+ D +           I LQ G+NKGA+QAGM   G +R I D   G +  D   + + LQ G ++GA+Q+G + G  R I D +
Sbjct:  159 GQCVIGLQMGTNKCASQAGMNAYGTRRHLYDPKAHIQPPMDNTTISLQMGTNKGASQAGMTAPGTRRAIYDQKLGTDKCD--NSTMSLQMGFSQGANQSGQNFGLGRQIYDAK 269

[Close]

BLAST of Calponin vs. Planmine SMEST
Match: SMESG000057599.1 (SMESG000057599.1)

HSP 1 Score: 256.144 bits (653), Expect = 8.068e-86
Identity = 128/130 (98.46%), Postives = 130/130 (100.00%), Query Frame = 1

Query:   85 IGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            IGLQAGSNKGASQ+GMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGA+
Sbjct:  176 IGLQAGSNKGASQSGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAS 305

HSP 2 Score: 234.187 bits (596), Expect = 2.822e-77
Identity = 118/135 (87.41%), Postives = 124/135 (91.85%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGA--SQTGMSMGAVRHIAD 399
            QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGA+QAGMRIG QRFINDV++G+EMSDEGKT IGLQ G +K    SQ+GMS GA RHI D
Sbjct:  227 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGASQAGMRIGTQRFINDVTTGVEMSDEGKTTIGLQMGPDKSKVDSQSGMSFGAQRHITD 361

[Close]

BLAST of Calponin vs. Planmine SMEST
Match: SMESG000057600.1 (SMESG000057600.1)

HSP 1 Score: 256.144 bits (653), Expect = 8.888e-83
Identity = 139/198 (70.20%), Postives = 147/198 (74.24%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKG----------------------------------------ASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            QAGMRIG QRFINDVS+G+E+SD GK  IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D+AKGVIGLQAGSNKGATQAGMRIG QRFINDVS+G+E+SD GK  IGLQAGSNKG                                        ASQTGMSMGAVRHIADIRCDEM D+AKGVIGLQAGSNKGAT
Sbjct:  300 QAGMRIGTQRFINDVSAGVEISDSGKNVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDDAKGVIGLQAGSNKGATQAGMRIGTQRFINDVSTGVEISDSGKNVIGLQAGSNKGATQAGMRIGTQRFINDVSTGVEISDSGKNVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDDAKGVIGLQAGSNKGAT 497

HSP 2 Score: 254.218 bits (648), Expect = 4.847e-82
Identity = 138/198 (69.70%), Postives = 147/198 (74.24%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKG----------------------------------------VIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q+GMRIG QRFINDVS+G+E+SDEGK+ IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D AKG                                        VIGLQAGSNKGATQAGMRIG QRFINDVS+G+E+SD GK  IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D+AKGVIGLQAGSNKGAT
Sbjct:  181 QSGMRIGTQRFINDVSTGVEISDEGKSVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDSAKGVIGLQAGSNKFASQTGMRIGTQRFINDVSTGVEISDSGKNVIGLQAGSNKGATQAGMRIGTQRFINDVSAGVEISDSGKNVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDDAKGVIGLQAGSNKGAT 378

HSP 3 Score: 243.432 bits (620), Expect = 5.703e-78
Identity = 127/159 (79.87%), Postives = 138/159 (86.79%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCD-EMSDEAKGVIGLQAGSNKGAT 474
            QAGMRIG QRFINDVS+G+E+SD GK  IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D+AKGVIGLQAGSNKGATQAGMRIG QRFINDVS+G+E+SD GKT IGLQAGSNKGA+Q GM +G  R I D+    E+SDE K VIGLQAGSNKGAT
Sbjct:  419 QAGMRIGTQRFINDVSTGVEISDSGKNVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDDAKGVIGLQAGSNKGATQAGMRIGTQRFINDVSTGVEISDSGKTVIGLQAGSNKGATQAGMRIGTQRFINDVSNGIEISDEGKNVIGLQAGSNKGAT 577

HSP 4 Score: 159.073 bits (401), Expect = 4.402e-46
Identity = 80/102 (78.43%), Postives = 90/102 (88.24%), Query Frame = 1

Query:  169 CDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
             +E     +G+IGLQAGSNKGA+Q+GMRIG QRFINDVS+G+E+SDEGK+ IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D AKGVIGLQAGSNK A+
Sbjct:  158 TEEQLRSGQGIIGLQAGSNKGASQSGMRIGTQRFINDVSTGVEISDEGKSVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDSAKGVIGLQAGSNKFAS 259

HSP 5 Score: 72.7886 bits (177), Expect = 2.215e-15
Identity = 36/56 (64.29%), Postives = 43/56 (76.79%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGA--SQTGMSMGAVRHIAD 162
            QAGMRIG QRFIND+ +G+EMSD+GK  IGLQ G ++    SQ+GMS GA RHI D
Sbjct:  578 QAGMRIGTQRFINDIQTGVEMSDKGKNIIGLQMGPDQSQVDSQSGMSFGAQRHITD 633

[Close]

BLAST of Calponin vs. Planmine SMEST
Match: SMESG000057600.1 (SMESG000057600.1)

HSP 1 Score: 255.758 bits (652), Expect = 1.161e-82
Identity = 139/198 (70.20%), Postives = 147/198 (74.24%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKG----------------------------------------ASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            QAGMRIG QRFINDVS+G+E+SD GK  IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D+AKGVIGLQAGSNKGATQAGMRIG QRFINDVS+G+E+SD GK  IGLQAGSNKG                                        ASQTGMSMGAVRHIADIRCDEM D+AKGVIGLQAGSNKGAT
Sbjct:  307 QAGMRIGTQRFINDVSAGVEISDSGKNVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDDAKGVIGLQAGSNKGATQAGMRIGTQRFINDVSTGVEISDSGKNVIGLQAGSNKGATQAGMRIGTQRFINDVSTGVEISDSGKNVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDDAKGVIGLQAGSNKGAT 504

HSP 2 Score: 254.218 bits (648), Expect = 6.255e-82
Identity = 138/198 (69.70%), Postives = 147/198 (74.24%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKG----------------------------------------VIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            Q+GMRIG QRFINDVS+G+E+SDEGK+ IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D AKG                                        VIGLQAGSNKGATQAGMRIG QRFINDVS+G+E+SD GK  IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D+AKGVIGLQAGSNKGAT
Sbjct:  188 QSGMRIGTQRFINDVSTGVEISDEGKSVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDSAKGVIGLQAGSNKFASQTGMRIGTQRFINDVSTGVEISDSGKNVIGLQAGSNKGATQAGMRIGTQRFINDVSAGVEISDSGKNVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDDAKGVIGLQAGSNKGAT 385

HSP 3 Score: 243.432 bits (620), Expect = 7.389e-78
Identity = 127/159 (79.87%), Postives = 138/159 (86.79%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCD-EMSDEAKGVIGLQAGSNKGAT 474
            QAGMRIG QRFINDVS+G+E+SD GK  IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D+AKGVIGLQAGSNKGATQAGMRIG QRFINDVS+G+E+SD GKT IGLQAGSNKGA+Q GM +G  R I D+    E+SDE K VIGLQAGSNKGAT
Sbjct:  426 QAGMRIGTQRFINDVSTGVEISDSGKNVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDDAKGVIGLQAGSNKGATQAGMRIGTQRFINDVSTGVEISDSGKTVIGLQAGSNKGATQAGMRIGTQRFINDVSNGIEISDEGKNVIGLQAGSNKGAT 584

HSP 4 Score: 159.073 bits (401), Expect = 5.095e-46
Identity = 80/102 (78.43%), Postives = 90/102 (88.24%), Query Frame = 1

Query:  169 CDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
             +E     +G+IGLQAGSNKGA+Q+GMRIG QRFINDVS+G+E+SDEGK+ IGLQAGSNK ASQTGMSMGAVRHIADIRCDEM D AKGVIGLQAGSNK A+
Sbjct:  165 TEEQLRSGQGIIGLQAGSNKGASQSGMRIGTQRFINDVSTGVEISDEGKSVIGLQAGSNKFASQTGMSMGAVRHIADIRCDEMCDSAKGVIGLQAGSNKFAS 266

HSP 5 Score: 72.4034 bits (176), Expect = 2.329e-15
Identity = 36/56 (64.29%), Postives = 43/56 (76.79%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGA--SQTGMSMGAVRHIAD 162
            QAGMRIG QRFIND+ +G+EMSD+GK  IGLQ G ++    SQ+GMS GA RHI D
Sbjct:  585 QAGMRIGTQRFINDIQTGVEMSDKGKNIIGLQMGPDQSQVDSQSGMSFGAQRHITD 640

[Close]

BLAST of Calponin vs. Planmine SMEST
Match: SMESG000057599.1 (SMESG000057599.1)

HSP 1 Score: 235.343 bits (599), Expect = 3.355e-78
Identity = 118/135 (87.41%), Postives = 124/135 (91.85%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGA--SQTGMSMGAVRHIAD 399
            QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGA+QAGMRIG QRFINDV++G+EMSDEGKT IGLQ G +K    SQ+GMS GA RHI D
Sbjct:  188 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGASQAGMRIGTQRFINDVTTGVEMSDEGKTTIGLQMGPDKSKVDSQSGMSFGAQRHITD 322

HSP 2 Score: 185.652 bits (470), Expect = 1.171e-58
Identity = 92/101 (91.09%), Postives = 97/101 (96.04%), Query Frame = 1

Query:  172 DEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            +E    ++G+IGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGA+
Sbjct:  166 EEQLRSSQGIIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAS 266

[Close]

BLAST of Calponin vs. Planmine SMEST
Match: SMESG000067773.1 (SMESG000067773.1)

HSP 1 Score: 144.436 bits (363), Expect = 2.419e-42
Identity = 77/142 (54.23%), Postives = 98/142 (69.01%), Query Frame = 1

Query:   58 EMSDE----GKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGA 471
            + SDE    G+  I LQ+G+NK ASQ+GMS G VRHIADIRCD+++D  KG+IGLQ G+NK A+Q GM IG  R I D+        E  + I LQ GSN+GASQ GM +G VRH++DI+C E + EA+ VI LQ G+N GA
Sbjct:  163 QFSDEQLRMGEGIINLQSGTNKFASQSGMSFGGVRHIADIRCDDLNDSGKGIIGLQMGTNKYASQKGMSIGAVRHIADIRCE-SNCPEAASIINLQYGSNQGASQKGMVIGGVRHVSDIKCAESNKEAQSVISLQYGTNLGA 303

HSP 2 Score: 138.272 bits (347), Expect = 5.550e-40
Identity = 77/154 (50.00%), Postives = 101/154 (65.58%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRC-DEMSDEAKGVIGLQAGS 459
            Q+GM  GG R I D+    +++D GK  IGLQ G+NK ASQ GMS+GAVRHIADIRC+    EA  +I LQ GSN+GA+Q GM IGG R ++D+    E + E ++ I LQ G+N GA+QTGM +G  RHI DI C  E +  +  ++ LQ G 
Sbjct:  188 QSGMSFGGVRHIADIRCD-DLNDSGKGIIGLQMGTNKYASQKGMSIGAVRHIADIRCESNCPEAASIINLQYGSNQGASQKGMVIGGVRHVSDIKCA-ESNKEAQSVISLQYGTNLGANQTGMRIGTQRHITDISCGIEPNKMSSNMVSLQMGP 339

HSP 3 Score: 117.087 bits (292), Expect = 6.291e-32
Identity = 66/135 (48.89%), Postives = 84/135 (62.22%), Query Frame = 1

Query:    1 QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSN--KGASQTGMSMGAVRHIAD 399
            Q GM IG  R I D+        E  + I LQ GSN+GASQ GM +G VRH++DI+C E + EA+ VI LQ G+N GA Q GMRIG QR I D+S G+E +      + LQ G +  + A+Q+GMS GA RHI D
Sbjct:  227 QKGMSIGAVRHIADIRCE-SNCPEAASIINLQYGSNQGASQKGMVIGGVRHVSDIKCAESNKEAQSVISLQYGTNLGANQTGMRIGTQRHITDISCGIEPNKMSSNMVSLQMGPSMKEVANQSGMSFGAQRHIND 360

HSP 4 Score: 104.375 bits (259), Expect = 4.602e-27
Identity = 55/101 (54.46%), Postives = 71/101 (70.30%), Query Frame = 1

Query:  172 DEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQAGSNKGAT 474
            DE     +G+I LQ+G+NK A+Q+GM  GG R I D+    +++D GK  IGLQ G+NK ASQ GMS+GAVRHIADIRC+    EA  +I LQ GSN+GA+
Sbjct:  166 DEQLRMGEGIINLQSGTNKFASQSGMSFGGVRHIADIRCD-DLNDSGKGIIGLQMGTNKYASQKGMSIGAVRHIADIRCESNCPEAASIINLQYGSNQGAS 265

The following BLAST results are available for this feature:

BLAST of Calponin vs. Ensembl Human
BLAST of Calponin vs. Ensembl Celegans
BLAST of Calponin vs. Ensembl Fly
BLAST of Calponin vs. Ensembl Zebrafish
BLAST of Calponin vs. Ensembl Xenopus
BLAST of Calponin vs. Ensembl Mouse
BLAST of Calponin vs. UniProt/SwissProt
BLAST of Calponin vs. TrEMBL
BLAST of Calponin vs. Ensembl Cavefish
BLAST of Calponin vs. Ensembl Sea Lamprey
BLAST of Calponin vs. Ensembl Yeast
BLAST of Calponin vs. Ensembl Nematostella
BLAST of Calponin vs. Ensembl Medaka
BLAST of Calponin vs. Planmine SMEST

BLAST of Calponin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CNN1	4.015e-18	46.15	calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155]	[more]
CNN1	7.013e-18	46.15	calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155]	[more]
CNN1	7.013e-18	46.15	calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155]	[more]
CNN1	1.031e-17	45.76	calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155]	[more]
CNN3	2.065e-15	43.59	calponin 3 [Source:HGNC Symbol;Acc:HGNC:2157]	[more]

BLAST of Calponin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
clik-1	6.890e-15	37.58	CaLponIn-liKe proteins [Source:UniProtKB/TrEMBL;A...	[more]
clik-1	6.890e-15	37.58	CaLponIn-liKe proteins [Source:UniProtKB/TrEMBL;A...	[more]
unc-87	1.524e-9	37.12	pep chromosome:WBcel235:I:6761228:6767797:-1 gene:...	[more]
clik-2	5.083e-7	30.90	CaLponIn-liKe proteins [Source:RefSeq peptide;Acc...	[more]
clik-2	5.083e-7	30.90	CaLponIn-liKe proteins [Source:RefSeq peptide;Acc...	[more]

BLAST of Calponin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calponin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cnn1b	8.210e-18	44.44	calponin 1, basic, smooth muscle, b [Source:ZFIN;A...	[more]
cnn3a	5.267e-16	42.98	calponin 3, acidic a [Source:ZFIN;Acc:ZDB-GENE-030...	[more]
cnn2	4.037e-15	40.71	calponin 2 [Source:ZFIN;Acc:ZDB-GENE-030131-542]	[more]
cnn3b	1.632e-14	42.11	calponin 3, acidic b [Source:ZFIN;Acc:ZDB-GENE-050...	[more]
cnn3b	1.798e-14	42.11	calponin 3, acidic b [Source:ZFIN;Acc:ZDB-GENE-050...	[more]

BLAST of Calponin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
slc5a8.1	6.173e-19	47.50	solute carrier family 5 member 8, gene 1 [Source:X...	[more]
tfdp1	1.003e-15	42.61	transcription factor Dp-1 [Source:Xenbase;Acc:XB-G...	[more]
tfdp1	1.728e-15	42.61	transcription factor Dp-1 [Source:Xenbase;Acc:XB-G...	[more]
cnn1	4.950e-15	41.59	calponin 1, basic, smooth muscle [Source:NCBI gene...	[more]

BLAST of Calponin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cnn1	4.104e-18	46.15	calponin 1 [Source:MGI Symbol;Acc:MGI:104979]	[more]
Cnn1	6.591e-18	45.76	calponin 1 [Source:MGI Symbol;Acc:MGI:104979]	[more]
Cnn3	1.685e-15	43.59	calponin 3, acidic [Source:MGI Symbol;Acc:MGI:1919...	[more]
Cnn3	2.343e-15	42.61	calponin 3, acidic [Source:MGI Symbol;Acc:MGI:1919...	[more]
Cnn2	3.233e-13	38.94	calponin 2 [Source:MGI Symbol;Acc:MGI:105093]	[more]

BLAST of Calponin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P26932\|CNN1_CHICK	4.730e-20	47.33	Calponin-1 OS=Gallus gallus OX=9031 GN=CNN1 PE=1 S...	[more]
sp\|Q7YRL2\|CNN1_SHEEP	4.425e-17	45.76	Calponin-1 OS=Ovis aries OX=9940 GN=CNN1 PE=2 SV=1	[more]
sp\|Q08092\|CNN1_PIG	4.471e-17	45.76	Calponin-1 OS=Sus scrofa OX=9823 GN=CNN1 PE=2 SV=1	[more]
sp\|Q08091\|CNN1_MOUSE	4.610e-17	45.76	Calponin-1 OS=Mus musculus OX=10090 GN=Cnn1 PE=1 S...	[more]
sp\|Q2HJ38\|CNN1_BOVIN	4.658e-17	45.76	Calponin-1 OS=Bos taurus OX=9913 GN=CNN1 PE=2 SV=1	[more]

BLAST of Calponin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0R3S938	8.446e-57	65.82	Transgelin OS=Hymenolepis diminuta OX=6216 GN=HDID...	[more]
A0A564YRY7	1.077e-56	65.82	Transgelin OS=Hymenolepis diminuta OX=6216 GN=WMSI...	[more]
A0A3G1GHW9	8.409e-56	61.39	Transgelin (Fragment) OS=Crenomytilus grayanus OX=...	[more]
R7UJ28	4.670e-55	62.66	Transgelin OS=Capitella teleta OX=283909 GN=CAPTED...	[more]
A0A183SYR3	5.790e-55	71.22	Transgelin OS=Schistocephalus solidus OX=70667 GN=...	[more]

BLAST of Calponin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cnn1b	4.044e-16	42.74	calponin 1 [Source:NCBI gene;Acc:103040806]	[more]
ENSAMXT00000037688.1	5.294e-15	39.04	calponin-3-like [Source:NCBI gene;Acc:103046041]	[more]
ENSAMXT00000006562.2	6.603e-15	40.77	calponin-3-like [Source:NCBI gene;Acc:103046041]	[more]
cnn3a	7.207e-15	42.11	calponin 3 [Source:NCBI gene;Acc:103024651]	[more]
cnn3a	8.074e-15	42.11	calponin 3 [Source:NCBI gene;Acc:103024651]	[more]

BLAST of Calponin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calponin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calponin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calponin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
cnn1b	1.827e-17	46.96	calponin 1 [Source:NCBI gene;Acc:101163085]	[more]
cnn3b	3.019e-15	42.98	calponin 3 [Source:NCBI gene;Acc:101163038]	[more]
ENSORLT00000007021.2	5.813e-14	40.71	calponin 2 [Source:NCBI gene;Acc:101165178]	[more]

BLAST of Calponin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000057599.1	8.068e-86	98.46	SMESG000057599.1	[more]
SMESG000057600.1	8.888e-83	70.20	SMESG000057600.1	[more]
SMESG000057600.1	1.161e-82	70.20	SMESG000057600.1	[more]
SMESG000057599.1	3.355e-78	87.41	SMESG000057599.1	[more]
SMESG000067773.1	2.419e-42	54.23	SMESG000067773.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30015168 ID=SMED30015168|Name=Calponin|organism=Schmidtea mediterranea sexual|type=transcript|length=474bp
CAAGCAGGAATGAGAATTGGAGGCCAGAGATTCATCAATGATGTTTCTAG
TGGTCTTGAAATGAGTGATGAAGGCAAAACCTGCATTGGTCTTCAAGCTG
GTTCGAATAAAGGTGCCAGTCAAACTGGAATGAGTATGGGAGCAGTCCGA
CATATTGCTGACATTCGATGTGACGAAATGAGTGATGAAGCAAAGGGAGT
CATTGGTTTACAAGCTGGTTCAAATAAAGGTGCGACACAAGCAGGAATGA
GAATTGGAGGCCAGAGATTCATCAATGATGTTTCTAGTGGTCTTGAAATG
AGTGATGAAGGCAAAACCTGCATTGGTCTTCAAGCTGGTTCGAATAAAGG
TGCCAGTCAAACTGGAATGAGTATGGGAGCAGTCCGACATATTGCTGACA
TTCGATGTGACGAAATGAGTGATGAAGCAAAGGGAGTCATTGGTTTACAA
GCTGGTTCAAATAAAGGTGCGACA

protein sequence of SMED30015168-orf-1

>SMED30015168-orf-1 ID=SMED30015168-orf-1|Name=SMED30015168-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=158bp
QAGMRIGGQRFINDVSSGLEMSDEGKTCIGLQAGSNKGASQTGMSMGAVR
HIADIRCDEMSDEAKGVIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEM
SDEGKTCIGLQAGSNKGASQTGMSMGAVRHIADIRCDEMSDEAKGVIGLQ
AGSNKGAT

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0005516	calmodulin binding
GO:0003779	actin binding

Vocabulary: **biological process**
Term	Definition
GO:0031032	actomyosin structure organization
GO:0007010	cytoskeleton organization

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0000428	musculature system
PLANA:0000478	pharynx musculature

Vocabulary: **INTERPRO**
Term	Definition
IPR000557	Calponin_repeat

Vocabulary: **cellular component**
Term	Definition
GO:0005856	cytoskeleton

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000557	Calponin repeat	PFAM	PF00402	Calponin	coord: 68..91 e-value: 1.3E-11 score: 43.9 coord: 29..52 e-value: 1.2E-12 score: 47.2
IPR000557	Calponin repeat	PROSITE	PS01052	CALPONIN_1	coord: 68..86
IPR000557	Calponin repeat	PROSITE	PS01052	CALPONIN_1	coord: 29..47
IPR000557	Calponin repeat	PROSITE	PS51122	CALPONIN_2	coord: 68..92 score: 10.498
IPR000557	Calponin repeat	PROSITE	PS51122	CALPONIN_2	coord: 29..53 score: 10.903
None	No IPR available	PANTHER	PTHR47385:SF3		coord: 24..53 coord: 64..93
None	No IPR available	PANTHER	PTHR47385	FAMILY NOT NAMED	coord: 24..53 coord: 64..93

Main menu

Calponin

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 19

Owlery

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