5-hydroxytryptamine receptor

Query:  122 SNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIA-----KNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRH---SCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CRK 1399
             N T  S    + +V+  ++   LI     GN  V+ ++ L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    ++ L+WL+  LISIPP+ GW+    + +   C  S   GY IY+TFGAFYIP ++M+VLYGRI++ A     K    ++      R   S  P    S N    S    +  ++     +              C    +R       L + E   V NS   +P             S+   T     S  R    K  ++     K +   E K + TLG+IMG F +CWLPFFIV ++ P  +         +   +P  +  +  WLGY NS LNP+IY  FNK+F+  FK+I+ C+ CR+
Sbjct:   23 GNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGAL--------------CANGAVRQGDDGAALEVIEVHRVGNSKEHLP-----------LPSEAGPTPCAPASFER----KNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCE---------SSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 422          

Query:  173 GIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVT-MVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIY----------QIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTD-LRHSC------QLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFC 1387
              +  +LI    FGN LV ++V   K LQT  N LIV+LAV+D+LVA LV+P     ++ G W F+ I CD F+  DV++CTASILNLCAISIDRY  +  P  Y  + +++  VT M+ + W++S  IS P LFG     +  +CI ++   + +Y++  +FY+P I+ +++Y +IY             ++S A  + L++        P  +  C    KS+ S   ++     + +     +   +  S +  +  R+S       QLTLP+     +     PD   K  +N              +    +  T+     M   K S Q E KA   L +++G F ICWLPFFI  ILN     IH +       +IP  +   F WLGY NS +NPIIY  FN EFR  F +IL C
Sbjct:   38 ATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA-DQNECIIANP-AFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVVQEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPS--HHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILN-----IHCD------CNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 445          

Query:  173 GIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVT-MVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVL-LSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFC 1387
              +  +LI    FGN LV ++V   K LQT  N LIV+LAV+D+LVA LV+P     ++ G W F+ I CD F+  DV++CTASILNLCAISIDRY  +  P  Y  + +++  VT M+ + W++S  IS P LFG     +  +CI ++   + +Y++  +FY+P I+ +++Y +IY + +      +  +S R   +     +       +  + ++ S TS   +   T+++     +   T  D  H    + P+        P  P+        + ++  H    ++  +    +  T+     M   K S Q E KA   L +++G F ICWLPFFI  ILN     IH +       +IP  +   F WLGY NS +NPIIY  FN EFR  F +IL C
Sbjct:   38 ATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA-DQNECIIANP-AFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKEAARRAQELEMEMLSSTSPPER---TRYSPIPPSHHQLTLPDPSHHGLHSTPDS-------PAKPE-------KNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILN-----IHCD------CNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 414          

Query:  158 NEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQK--YEIGQCIYS-DCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRC 1393
            +++++ +    L L T   N LVI ++I+ ++L  P N LI +LAV+D LVA+LV+P + +Y ++  W+  ++VCD ++  D+  CT SIL+L AI++DRY  IT   +Y  KR  +    M+ + W++S  IS+PPLF W+ +      +CI   D +   IY+TFGAFYIP  ++++LY   Y+I + +  +  + ++ R  I+K+ +               +      S +  ST + +  ++    T  D  HS                                     T+R L S  +    K W+      K S   E KA  TLG+I+G F ICWLPFF+ +++  +               I + +S    WLGY NS +NP+IY  FN++F+  F++++ CRC
Sbjct:   22 SKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLF-WRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILY---YKIYRAAKTLYHKRQASR--IAKEEVN-----------GQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHS-------------------------------------TVRSLRSEFKHE--KSWR----RQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNV----------CDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC 366          

Query:  173 GIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVT-MVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIY----------QIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXX-----XXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFC 1387
              +  +LI    FGN LV ++V   K LQT  N LIV+LAV+D+LVA LV+P     ++ G W F+ I CD F+  DV++CTASILNLCAISIDRY  +  P  Y  + +++  VT M+ + W++S  IS P LFG     +  +CI ++   + +Y++  +FY+P I+ +++Y +IY             ++S A  + L++        P  +  C    KS                + ++     +  S   R+  +       QLTLP+     +     PD   K  +N              +    +  T+     M   K S Q E KA   L +++G F ICWLPFFI  ILN     IH +       +IP  +   F WLGY NS +NPIIY  FN EFR  F +IL C
Sbjct:   38 ATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNA-DQNECIIANP-AFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPS--HHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILN-----IHCD------CNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 443          

Query:  110 MANVSNITNHSKYAFAN--EVVLGIV-FCVLILGTAFGNGLVILSVILAKRLQTP-NNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSC--QLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQ---SEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRK 1456
            M N++   + +K A  N  E VL I     ++L   FGN LV+++V   ++L+    N LIV+LAV+DMLV LLV+PL   Y++ G W    I+C+ ++  DVL  TASIL++CAIS+DRY  +T P  Y A R    M   +G+SW+VS LI +PP+FGW+ +   G+C  S  LGY +Y++ G+FYIP +I+I++Y +IY I          ++  R  + +     H+ N     S ++ +    +  ++      I     +  T  D+ +    QL    + L R       D            + H+       S     LT++ ++     KR  +    E +A   LG+I+  F + WLPFF++ ++        G+++       P  V + F WLGY NS +NP+IY  FN+EF+          C++L+   + E ++  + EF K
Sbjct:    1 MWNLNCSESDTKVACLNLGEAVLTISSMLTVMLLIIFGNLLVVVTVYRDRKLRMQRQNWLIVSLAVADMLVGLLVMPLTLTYEIVGEWTMGNILCEIWLALDVLFVTASILHICAISLDRYFSVTSPLTYPATRTPLRMFIYIGVSWIVSLLICLPPIFGWRPERAEGECSVSTDLGYVLYSSLGSFYIPVVILIIVYAKIYSIT---------IRHSRQRLKETERRDHTLNMLTIRSSTNERYNMEY--ELEENSDPIEDEKEKVVTNRDMINKVCWQLRKISEELPRQGVKIALD------------TNHN-------SPPASDLTRKLEEKKFCEKRKRKLKAKERQATLLLGIILSAFILSWLPFFLIYVIGAF-----GHEA-------PPLVFKFFFWLGYCNSGINPVIYTVFNREFKRGL-------CKQLH---KFERFIHPLMEFYK 406          

Query:  110 MANVSNITNHSKYAFAN--EVVLGIV-FCVLILGTAFGNGLVILSVILAKRLQTP-NNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDT-----LTKRWKDIMHSSKRSSQ---SEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRK 1456
            M N++   + +K A  N  E VL I     ++L   FGN LV+++V   ++L+    N LIV+LAV+DMLV LLV+PL   Y++ G W    I+C+ ++  DVL  TASIL++CAIS+DRY  +T P  Y A R    M   +G+SW+VS LI +PP+FGW+ +   G+C  S  LGY +Y++ G+FYIP +I+I++Y +IY I          ++  R  + +     H+ N     S ++ +    +  ++      I     +  T  D+ +     L   R +    P                 +    + + L  + ++     LT++ ++     KR  +    E +A   LG+I+  F + WLPFF++ ++        G+++       P  V + F WLGY NS +NP+IY  FN+EF+          C++L+   + E ++  + EF K
Sbjct:    1 MWNLNCSESDTKVACLNLGEAVLTISSMLTVMLLIIFGNLLVVVTVYRDRKLRMQRQNWLIVSLAVADMLVGLLVMPLTLTYEIVGEWTMGNILCEIWLALDVLFVTASILHICAISLDRYFSVTSPLTYPATRTPLRMFIYIGVSWIVSLLICLPPIFGWRPERAEGECSVSTDLGYVLYSSLGSFYIPVVILIIVYAKIYSIT---------IRHSRQRLKETERRDHTLNMLTIRSSTNERYNMEY--ELEENSDPIEDEKEKVVTNRDMINKVCWQL---RKISEELP-----------------RQGVKVSIALDTNHNSPPASDLTRKLEEKKFCEKRKRKLKAKERQATLLLGIILSAFILSWLPFFLIYVIGAF-----GHEA-------PPLVFKFFFWLGYCNSGINPVIYTVFNREFKRGL-------CKQLH---KFERFIHPLMEFYK 408          

Query:  122 SNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQ-TPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQK------YEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSI----RGSISKD----PMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRC 1393
            + I +  +      V+L  V  VLIL    GN  VIL++I+ + L+  P   LI +LAV+D+LV ++V PL   + + G W    +VCDF+I  DVL+CTASIL+L AI++DRY  IT    Y+  R  + +  M+ + W  S LIS+ P  GWK +       +   C+ S  + YQ+++T  AFYIP I +I +Y +I + AK     +   +++      +I +     P     C        SDIQ+      + +S K+    N   S  + + R   Q          N  PG             + +   T I      S+  + KR +    S++   + E KA  TL +I G F  CW PFF+V I  PI               I   + ++ LWLGY NS LNPIIY  F+++FR  FK I+   C
Sbjct:   38 AEIFSDIERPLVQTVILASVLLVLILSCFIGNLFVILAIIMERDLRGRPQYYLIFSLAVADLLVGMIVTPLGAWFTVTGTWNLGVVVCDFWISVDVLVCTASILHLVAIALDRYWSITD-ICYVQNRTPKRITLMLAVIWFTSLLISLAPFAGWKDEGFSDRVLKSHVCLISQQISYQVFSTATAFYIPLIAIICVYWKIMRAAKKRFKRERDRRTVIRPPPDAIDEKKAMMPKKSKKCPLPPAVVISDIQANGGTGGKTNSIKNPPRHNESSSSASEEERTMTQT---------NHAPG-------------DVTTQETKIDEENGRSKPGIVKRRRRTKESNE--MKRERKAWRTLAIITGTFVACWTPFFLVSIYRPICG-----------CQISPVLEQVTLWLGYLNSALNPIIYTVFSQDFRAAFKRIIKRMC 440          

Query:  122 SNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQ-TPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQK------YEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSI----RGSISKD----PMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRC 1393
            + I +  +      V+L  V  VLIL    GN  VIL++I+ + L+  P   LI +LAV+D+LV ++V PL   + + G W    +VCDF+I  DVL+CTASIL+L AI++DRY  IT    Y+  R  + +  M+ + W  S LIS+ P  GWK +       +   C+ S  + YQ+++T  AFYIP I +I +Y +I + AK     +   +++      +I +     P     C        SDIQ+      + +S K+    N   S  + + R   Q          N  PG             + +   T I      S+  + KR +    S++   + E KA  TL +I G F  CW PFF+V I  PI               I   + ++ LWLGY NS LNPIIY  F+++FR  FK I+   C
Sbjct:   38 AEIFSDIERPLVQTVILASVLLVLILSCFIGNLFVILAIIMERDLRGRPQYYLIFSLAVADLLVGMIVTPLGAWFTVTGTWNLGVVVCDFWISVDVLVCTASILHLVAIALDRYWSITD-ICYVQNRTPKRITLMLAVIWFTSLLISLAPFAGWKDEGFSDRVLKSHVCLISQQISYQVFSTATAFYIPLIAIICVYWKIMRAAKKRFKRERDRRTVIRPPPDAIDEKKAMMPKKSKKCPLPPAVVISDIQANGGTGGKTNSIKNPPRHNESSSSASEEERTMTQT---------NHAPG-------------DVTTQETKIDEENGRSKPGIVKRRRRTKESNE--MKRERKAWRTLAIITGTFVACWTPFFLVSIYRPICG-----------CQISPVLEQVTLWLGYLNSALNPIIYTVFSQDFRAAFKRIIKRMC 440          

Query:  161 EVVLG-IVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKG-YWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYE---IGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRH----SCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKI--IHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSES 1426
            E+VLG I + V+I  T  GN LV+++V   + L+   N  +V+LA SD+ VA+ V+PL  +  L G  W+    VC FF   D+LLCT+SILNLCAI++DRY  I  P  Y  KR  + +  ++ + W++S LIS+PP+ GW    E      C  S    + +++  G+F++P ++M+V+Y +I+  A+       ++++ RG  +   M I +        +  I+  +  SA+ SS       ++ +  TT  +++    SC++ + + +       G P+                             L KR K  +   KR+++       T+ VI+  F  CWLPFF+  ++ P  +   +H              V + F WLGY NS LNP +Y   N EFR  FK+IL C    L  R R  S
Sbjct:   45 ELVLGTITYLVIIAMTVVGNTLVVVAVFSYRPLKKVQNYFLVSLAASDLAVAIFVMPLHVVTFLAGGKWLLGVTVCQFFTTADILLCTSSILNLCAIALDRYWAIHNPINYAQKRTTKFVCIVIVIVWILSMLISVPPIIGWNNWQENMMEDSCGLSTEKAFVVFSAAGSFFLPLLVMVVVYVKIFISARQ------RIRTNRGRSAL--MRIQNAEGDDDYRKMSIKRASVESARTSSRTD--GGSLPKDETTKHMKYHNNGSCKVKVKDVK----EDEGNPNPTA-------------------------VLRKREKISVAKEKRAAK-------TIAVIIFVFSFCWLPFFVAYVIRPFCETCKLHAK------------VEQAFTWLGYINSSLNPFLYGILNLEFRRAFKKIL-CPKAVLEQRRRRMS 418          

Query:  176 IVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQ--KYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSS-QSEGKAIFTLGVIMGCFCICWLPFFIVQILNPI---FKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            I+F +L L   FGN LVILSV   + LQT  N  IV+LA++D+LVA++V+P A  + + G W   ++VCDF+I  DV+  T+SI NL AISIDRY+ +T+P +Y   +N+R +   + L W +SA I  P + G       E   C + +   + +Y++  +FYIP IIM+ LY  I++      A+ S+ +  R +       +   +     +Q+   ++T+    + S++H   S I      T+          E  +     P I DC    N  S      +    V+    + T+ K  K      ++SS + E KA  TL +++G F  CWLPFF   I++ +   FK        A +++          WLGY NSF+NP+IY  FN EFR  FK+I+
Sbjct:  383 ILFPILTL---FGNILVILSVCRERSLQTVTNYFIVSLAIADLLVAVVVMPFAVYFLVNGAWALPDVVCDFYIAMDVICSTSSIFNLVAISIDRYIAVTQPIKYAKHKNSRRVCLTILLVWAISAAIGSPIVLGLNNTPNREPDVCAFYNA-DFILYSSLSSFYIPCIIMVFLYWNIFK------ALRSRARKQRAARKPHLSELTGGSVIENIAQTRRLAETA----LDSSRH--ASRILPDEAATNTASGSNEEEDENAIS----PDIDDCHVIVNDKSTEFMLAT----VVEETGKFTIYKVHKASKKKREKSSAKKERKATKTLAIVLGVFLFCWLPFFSCNIMDAMCAKFKKDCRPGLTAYMMTT---------WLGYINSFVNPVIYTIFNPEFRKAFKKIM 757          

Query:  164 VVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPL--FGWKQKYEIGQCIYSDC--LGYQIYATFGAFYIPSIIMIVLYGRIYQIAK 715
            + + IV  ++ILGT  GN LV ++V + ++L+ P N L+V+LA+SD+ VALLV+P+A +Y++   W F  ++CD ++  DVL CTASILNLCAIS+DRYL ITKP +Y  KR  R M+  VG+ WL +A IS+PPL   G + + E GQ I + C    YQIYAT G+FYIP  +M+ +Y +I++ A+
Sbjct:  163 IFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLVMPMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLLILGNEHEDEEGQPICTVCQNFAYQIYATLGSFYIPLSVMLFVYYQIFRAAR 350          

Query: 1127 EGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGE 1447
            E KA  TLG+IM  F +CWLPFFI+ ++ P F+ +H          +P S+S LFLWLGY NS LNPIIY   N++FR PF+EIL+ RC  LN  +R   Y  Q GE
Sbjct:  449 EKKASTTLGIIMSAFTVCWLPFFILALIRP-FETMH----------VPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQEILYFRCSSLNTMMRENYYQDQYGE 544          

Query:  164 VVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPL--FGWKQKYEIGQCIYSDC--LGYQIYATFGAFYIPSIIMIVLYGRIYQIAK 715
            + + IV  ++ILGT  GN LV ++V + ++L+ P N L+V+LA+SD+ VALLV+P+A +Y++   W F  ++CD ++  DVL CTASILNLCAIS+DRYL ITKP +Y  KR  R M+  VG+ WL +A IS+PPL   G + + E GQ I + C    YQIYAT G+FYIP  +M+ +Y +I++ A+
Sbjct:  163 IFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLVMPMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLLILGNEHEDEEGQPICTVCQNFAYQIYATLGSFYIPLSVMLFVYYQIFRAAR 350          

Query: 1127 EGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGE 1447
            E KA  TLG+IM  F +CWLPFFI+ ++ P F+ +H          +P S+S LFLWLGY NS LNPIIY   N++FR PF+EIL+ RC  LN  +R   Y  Q GE
Sbjct:  449 EKKASTTLGIIMSAFTVCWLPFFILALIRP-FETMH----------VPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQEILYFRCSSLNTMMRENYYQDQYGE 544          

Query:  164 VVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAK-RNNRLMVTMVGLSWLVSALISIPPLFGWKQ--KYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRI 700
            ++L  VF   I+ T  GN LVIL+++  +RL+T  N  +++LAV+D+LV + V+P A    L G W    ++CD +I  DVLLCTASIL+LCAIS+DRYL +T+P  Y  K R+ RL + M+ + WL++  I+ PP+ GW +  + ++ +C Y+   GY I++  G+F+IP  +MI +Y RI
Sbjct:  117 IILIAVFATFIVVTVIGNTLVILAILTTRRLRTITNCFVMSLAVADLLVGIFVMPPAVAVHLIGSWQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPLTYSRKRRSKRLALIMILIVWLLALAITCPPMLGWYEPGRRDLRECRYNQNEGYVIFSAMGSFFIPMAVMIYVYARI 298          

Query: 1115 SSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPF 1369
            S + E K   TL +++G F  CWLPFFI  ++ P       +          Q +++   WLG+FNS +NP IY  ++ +FR  F
Sbjct:  531 SLKKENKTTQTLSIVVGGFIACWLPFFINYLITPFLAEHQAS----------QMLAKALTWLGWFNSAINPFIYAFYSVDFRAAF 605          

Query:  164 VVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAK-RNNRLMVTMVGLSWLVSALISIPPLFGWKQ--KYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRI 700
            ++L  VF   I+ T  GN LVIL+++  +RL+T  N  +++LAV+D+LV + V+P A    L G W    ++CD +I  DVLLCTASIL+LCAIS+DRYL +T+P  Y  K R+ RL + M+ + WL++  I+ PP+ GW +  + ++ +C Y+   GY I++  G+F+IP  +MI +Y RI
Sbjct:  117 IILIAVFATFIVVTVIGNTLVILAILTTRRLRTITNCFVMSLAVADLLVGIFVMPPAVAVHLIGSWQLGWVLCDIWISLDVLLCTASILSLCAISVDRYLAVTRPLTYSRKRRSKRLALIMILIVWLLALAITCPPMLGWYEPGRRDLRECRYNQNEGYVIFSAMGSFFIPMAVMIYVYARI 298          

Query: 1115 SSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPF 1369
            S + E K   TL +++G F  CWLPFFI  ++ P       +          Q +++   WLG+FNS +NP IY  ++ +FR  F
Sbjct:  531 SLKKENKTTQTLSIVVGGFIACWLPFFINYLITPFLAEHQAS----------QMLAKALTWLGWFNSAINPFIYAFYSVDFRAAF 605          

Query:  125 NITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQ---KYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            N TN + Y+ A  + L  +   LIL T  GN LV+++V+ ++ L+ P N+ +V+LA +D+LVA L++P +   +L GYW F E+ C+ ++  DVL CT+SI++LCAIS+DRY  +T+  +Y  KR  R +  M+ + WL+SA+IS PPL    +         C  +D   Y +Y++ G+F+ P +IMI++Y RIYQ+AK      S+ +      S  P   +  +   + S+ +    +S   +    + N ++         DL  S       KR    + P   D R+    +S +      +     S    +  ++ ++ +   K S   E +  F L V+MG F +CW PFF    L  I +            +IP  + + F W+GY NS LNP+IY  FN++FR  F++IL
Sbjct:   23 NSTNSTSYSPATIIGLAGLVSFLILFTIVGNVLVVIAVLTSRALKPPQNLFLVSLASADILVATLIIPFSLANELMGYWFFGEVWCNIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRNTVDERRPMCQLNDHTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRNMSEKRRDPDGGSGTPRLENGLS--REDSRRENGHCSSSPGERKPAEDNPDA---------DLEDSSSSDEKAKRSQNETAPSKKDRRSSRKNSSSSKHSSRKSRASSKSLDLFSSRRKRRNTISRKKISQAREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICR---------EPCAIPDPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAFQKIL 424          

Query:  125 NITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQ---KYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            N TN + Y+ A  + L  +   LIL T  GN LV+++V+ ++ L+ P N+ +V+LA +D+LVA L++P +   +L GYW F E+ C+ ++  DVL CT+SI++LCAIS+DRY  +T+  +Y  KR  R +  M+ + WL+SA+IS PPL    +         C  +D   Y +Y++ G+F+ P +IMI++Y RIYQ+AK      S+ +      S  P   +  +   + S+ +    +S   +    + N ++         DL  S       KR    + P   D R+    +S +      +     S    +  ++ ++ +   K S   E +  F L V+MG F +CW PFF    L  I +            +IP  + + F W+GY NS LNP+IY  FN++FR  F++IL
Sbjct:   23 NSTNSTSYSPATIIGLAGLVSFLILFTIVGNVLVVIAVLTSRALKPPQNLFLVSLASADILVATLIIPFSLANELMGYWFFGEVWCNIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRNTVDERRPMCQLNDHTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRNMSEKRRDPDGGSGTPRLENGLS--REDSRRENGHCSSSPGERKPAEDNPDA---------DLEDSSSSDEKAKRSQNETAPSKKDRRSSRKNSSSSKHSSRKSRASSKSLDLFSSRRKRRNTISRKKISQAREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICR---------EPCAIPDPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAFQKIL 424          

Query:  125 NITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQ---KYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            N TN + Y+ A  + L  +   LIL T  GN LV+++V+ ++ L+ P N+ +V+LA +D+LVA L++P +   +L GYW F E+ C+ ++  DVL CT+SI++LCAIS+DRY  +T+  +Y  KR  R +  M+ + WL+SA+IS PPL    +         C  +D   Y +Y++ G+F+ P +IMI++Y RIYQ+AK      S+ +      S  P   +  +   + S+ +    +S   +    + N ++         DL  S       KR    + P   D R+    +S +      +     S    +  ++ ++ +   K S   E +  F L V+MG F +CW PFF    L  I +            +IP  + + F W+GY NS LNP+IY  FN++FR  F++IL
Sbjct:   23 NSTNSTSYSPATIIGLAGLVSFLILFTIVGNVLVVIAVLTSRALKPPQNLFLVSLASADILVATLIIPFSLANELMGYWFFGEVWCNIYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKGMIVVVWLISAVISFPPLISMDRNTVDERRPMCQLNDHTWYILYSSIGSFFAPCVIMILVYIRIYQVAKTRTRNMSEKRRDPDGGSGTPRLENGLS--REDSRRENGHCSSSPGERKPAEDNPDA---------DLEDSSSSDEKAKRSQNETAPSKKDRRSSRKNSSSSKHSSRKSRASSKSLDLFSSRRKRRNTISRKKISQAREKRFTFVLAVVMGVFVVCWFPFFFSYSLYGICR---------EPCAIPDPLFKFFFWIGYCNSSLNPVIYTIFNQDFRRAFQKIL 424          

Query:  164 VVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIG-----QCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEK-------RLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQ---SEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCR 1396
             V  I   +++L T FGN +VI++V+  + L+ P N+ +V+LA +D+LVA LV+P +   +L G W F  + C+  +  DVL CT+SI++LCAIS+DRYL I++P QY  +R  R +   + + WL+SA+IS PPL    +  +        C  ++   Y +Y+T G+F+ P +IMI++Y RIYQIAK         +   G   KD        +          +     ++  + K      I  S   T     C+    E         +V        +           +   S + R +++ S+ +     K     + R       E +  F L V++G F ICW PFF    L  I            +  +P+ +   F W+GY NS LNP+IY  FN++FR  FK+IL  RC+
Sbjct:   19 AVFAITMTLIMLFTIFGNIMVIIAVLTCRSLRGPQNLFLVSLAAADILVATLVIPFSLAKELMGCWYFESLWCEIILALDVLFCTSSIIHLCAISLDRYLSISRPVQYGTQRTPRKIKGAIVVVWLISAIISFPPLVSMDKPQQAKGDPRTTCELNEDKWYILYSTIGSFFAPCLIMILVYVRIYQIAKK------HTRCPPGEPRKDSAVGRELQNGKDGGVDSANNPNIAPSKSEAVKQ--PPVITESAQKTKRSRRCKENKEESSSSGSDVEVVGGHDANGTNSNMAPLETVNKTPAQSQSYRNIIATSKGSQLANAKATGTPNTRRKAMIVREKRFTFVLAVVIGVFIICWFPFFFSYSLQAIC---------PDMCKVPEGLFTFFFWIGYCNSALNPLIYTIFNRDFRKAFKKILCKRCK 427          

Query:  164 VVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIG-----QCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEK-------RLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQ---SEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCR 1396
             V  I   +++L T FGN +VI++V+  + L+ P N+ +V+LA +D+LVA LV+P +   +L G W F  + C+  +  DVL CT+SI++LCAIS+DRYL I++P QY  +R  R +   + + WL+SA+IS PPL    +  +        C  ++   Y +Y+T G+F+ P +IMI++Y RIYQIAK         +   G   KD        +          +     ++  + K      I  S   T     C+    E         +V        +           +   S + R +++ S+ +     K     + R       E +  F L V++G F ICW PFF    L  I            +  +P+ +   F W+GY NS LNP+IY  FN++FR  FK+IL  RC+
Sbjct:   19 AVFAITMTLIMLFTIFGNIMVIIAVLTCRSLRGPQNLFLVSLAAADILVATLVIPFSLAKELMGCWYFESLWCEIILALDVLFCTSSIIHLCAISLDRYLSISRPVQYGTQRTPRKIKGAIVVVWLISAIISFPPLVSMDKPQQAKGDPRTTCELNEDKWYILYSTIGSFFAPCLIMILVYVRIYQIAKK------HTRCPPGEPRKDSAVGRELQNGKDGGVDSANNPNIAPSKSEAVKQ--PPVITESAQKTKRSRRCKENKEESSSSGSDVEVVGGHDANGTNSNMAPLETVNKTPAQSQSYRNIIATSKGSQLANAKATGTPNTRRKAMIVREKRFTFVLAVVIGVFIICWFPFFFSYSLQAIC---------PDMCKVPEGLFTFFFWIGYCNSALNPLIYTIFNRDFRKAFKKILCKRCK 427          

Query:  191 LILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQ-SEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            +IL T  GN LV+L++  ++ L+ P N+ +V+LA +D+LV  L++P +   ++ GYW F  + C  ++  D+L CT+SI++LCAISIDRY  +TK  +Y  KR  + +   + + W+VSA+IS PPL   K K++  +C+ +D   Y +++   +F++P +IMI+LY RIY++AK+      ++ S+R  +S        CN             ++ +     T H I +N        DL  S        +   +     P                S   + L  +S      R + I  S  R +Q  E +  F L V++G F ICW PFF    L  + +   G         I  ++   F W+GY NS LNPIIY  FN++FR  F+ IL
Sbjct:   43 IILSTVLGNILVVLAIFTSRALRAPQNLFLVSLASADILVGALIIPFSLAREVMGYWHFGSVWCSMYLALDILFCTSSIVHLCAISIDRYWSVTKAVKYNLKRTPKRIKRSIAIIWVVSAIISFPPLL--KSKHKEWECLLNDDTWYVLFSCTVSFFVPCLIMILLYCRIYRVAKH------RVSSLRNGVSD-------CN-------------SAAAGGTCETHHTIQNN--HEAEELDLEESTSSVHKFPKKHHHKTKDKPS---------------SAKAKRLSWSSNRGQQHRDQSICISQMRLTQLREKRLTFVLAVVIGGFVICWFPFFFTYSLESVCRKRCG---------ISDALFNFFFWIGYCNSSLNPIIYTVFNRDFRKAFRRIL 386          

Query:  116 NVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPL-FGWKQKYEIG--QCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRN----SFPGIPDCXXXXXXXXXXXXXHSTT-----IRVLLSASRDTLTKRWKDIMHSSKRSS-QSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            N S +     Y+     V+  +   L+L T FGN LVI++V+ ++ L+ P N+ +V+LA +D+LVA L++P +   +L GYW F +  C+ ++  DVL CT+SI++LCAIS+DRY  +++  +Y +KR  + +  ++ + W ++ALIS+PPL +  K K +    +C  ++   Y + ++  +F+ P +IMI++Y RIY IAK     +S  K ++      P      N              S ++  + T+  I S+  ++    D  H     L   R  RN    SF   P   N  + N    +   T      + ++   ++D+      D+  + K+S    E +  F L V++G F +CW PFF    L  I            L  IP SV + F W+GY NS LNP+IY  FN++FR  F+ IL
Sbjct:    2 NTSTMVAPLSYSIQATAVIAAIITFLVLFTIFGNVLVIIAVLTSRSLKAPQNLFLVSLAAADILVATLIIPFSLANELMGYWYFGKTWCEMYLALDVLFCTSSIVHLCAISLDRYWSVSQAIEYNSKRTPKRIKCIILIVWTLAALISLPPLIYKGKSKDQNAKPECKLNEEPWYILSSSICSFFAPCLIMILVYLRIYLIAKRRNRKNSTDKKLK---KMAPGLFSRTNKH------------SLNSSHTQTQCGIISSQEKTGLALDDLHCGVPVLSSTREERNGHSESFGLQPQGENLKHTNGCEPAVMDTVATVKGVMLMPKGAKDS------DLSSAKKKSYINREKRFTFVLAVVIGVFVLCWFPFFFTYSLGAI---------CTELCYIPDSVFQFFFWIGYCNSSLNPVIYTIFNQDFRKAFRRIL 406          

Query:  116 NVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAK 715
               N+T   + A + ++V  +    LIL   FGN  VI ++ L + LQT  N LI +LAV+D++V++LVLP+A   Q+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    ++ ++W+V   ISIPP+ GW+    + +   C  S+  GY IY+TFGAFYIP I+M+VLYG+I++ A+
Sbjct:   15 ETGNVT-EEEVALSYQIVTSLFLGTLILCAIFGNACVIAAIALERCLQTVANYLIGSLAVTDLMVSVLVLPMAAHNQVLNKWTLGQVTCDIFISLDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAVLISITWIVGFSISIPPMLGWRTPEDRSDPNACKISEDPGYTIYSTFGAFYIPLILMLVLYGKIFKAAR 216          

Query: 1076 TKRWKDIMHSSKR--SSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CRK 1399
            +++  D    +KR  +   E K + TLG+IMG F  CWLPFFIV ++ P  +  H          +P  + ++  WLGY NS LNPIIY  FNK+F++ FK+I+ C+ CR+
Sbjct:  310 SEKRNDRATDAKRKVALARERKTVKTLGIIMGTFIFCWLPFFIVALVLPFCETCH----------MPHLLFDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCKFCRQ 410          

Query:  143 KYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQL-KGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQ-CIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAA 727
             Y    ++V+G +  ++ L T  GN LV++SV   K+L+ P+N LIV+LA++D+ VA+ V+P  ++  L  G W+F  + C+ FI  DV+ CTASI+ LC ISIDRYL IT+P  Y  ++N R M  M+   WL+SA I++PPLFGW Q     + C+ S   GY IY+T  AFYIP  +M+ +Y RI++ AK SAA
Sbjct:   72 NYGHIEKLVIGAILSLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAIAVMPFVSVTDLIGGEWIFGHVFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGRCMAKMILCVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYRIFKAAKRSAA 268          

Query: 1121 QSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRS 1420
            + E KA  TLG+I+G F ICWLPFF++    P    I G + +     IP  +   FLWLGY NS +NP IY  FN++ RT ++ +L CR R +N ++ +
Sbjct:  318 KREQKAATTLGIIVGAFTICWLPFFLLSTARPF---ICGTECSC----IPLWLERTFLWLGYANSLINPFIYAFFNRDLRTTYRNLLQCRYRNINRKLSA 410          

Query:  158 NEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQK--YEIGQC-IYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKN 718
            ++++L ++  ++ L T   N  VI +V   ++L TP N LI +LA +D+LV++LVLP+A +Y + G W   +I+CD ++  D+  CTASIL+LC I++DRY  IT   +Y  KR  +  V M+ L W+ S  IS+PPLF W+Q    EI  C + +D + Y +Y+T GAFYIP++++I LYGRIY  A++
Sbjct:   17 SKIILTVILALITLATLLSNAFVITTVYQTRKLHTPANYLIASLAFTDLLVSILVLPIAIVYTVTGKWTLGQIICDMWLSSDITCCTASILHLCVIALDRYWAITDAVEYTKKRTPKRAVVMIALVWVFSISISMPPLF-WRQSKAEEIAVCAVNTDHILYTVYSTVGAFYIPTLLLIALYGRIYVEARS 205          

Query: 1094 IMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            ++   K  +  E KA  TLGVI+G + +CWLPFFI+ ++ PI K       +A       ++ + F WLGY NS +NPIIY   N++F+  F +++
Sbjct:  265 LLEKKKIMAARERKATKTLGVILGAYIVCWLPFFIISLVMPICK-------DACWFH--PAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLI 351          

Query:  122 SNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHS---CQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CR 1396
             N T  S   F+ +V+  ++   LI     GN  V+ ++ L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    ++ L+WL+  LISIPP+ GW+    +    +C  S   GY IY+TFGAFYIP ++M+VLYGRI++ A+           IR ++ K        +    S+    +S           +   N  +   C    +R       L + E   V NS   +P             S+   T  V     R    K  +      K +   E K + TLG+IMG F +CWLPFFIV ++ P  +         +   +P+ +  +  WLGY NS LNP+IY  FNK+F+  FK+I+ C+ CR
Sbjct:   23 GNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAAR---------FRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLP-----------LPSESGATSYVPACLER----KNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCE---------SSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR 421          

Query:  173 GIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVT-MVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIY----------QIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXX-----XXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVL-LSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFC 1387
             ++  +LI    FGN LV ++V   K LQT  N LIV+LAV+D+LVA LV+P     ++ G W F+ I CD F+  DV++CTASILNLCAISIDRY  +  P  Y  + +++  VT M+ + W++S  IS P LFG     +  +CI ++   + +Y++  +FY+P I+ +++Y +IY             ++S A  + LK+        P  +  C    KS                + ++     +  S   R+  +       QLTLP+     +     PD   K  +N      +    +   +    +  T+     M   K S Q E KA   L +++G F ICWLPFFI  ILN     IH +       +IP  +   F WLGY NS +NPIIY  FN EFR  F +IL C
Sbjct:   38 AMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNT-DQNECIIANP-AFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPS--HHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILN-----IHCD------CNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 444          

Query:  191 LILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPL-FGWKQKYE---IGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRN------------------------------SFPGIPDCXXXXXXXXXXXXXHSTTIR--VLLSASRDTLTKRWKDIMHSSKRSSQ--SEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR 1390
            LIL T FGN LVIL+V+ ++ L+ P N+ +V+LA +D+LVA L++P +   +L GYW F    C+ ++  DVL CT+SI++LCAIS+DRY  +++  +Y +KR  R +  ++   WL++A+IS+PPL +   Q+ E   + QC  +    Y + ++ G+F+ P +IMI++Y RIY IAK S      L + RGS   +    H       +S       +  S+   +  H           T +   +  L      L R+                              + P  P            +S+   T+R  VLLS +    + +W       +R +Q   E +  F L V++G F +CW PFF    L  I               +P  + + F W+GY NS LNP+IY  FN++FR  F+ IL CR
Sbjct:   22 LILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPHGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRG--LGAKRGSGEGESKKPHPAAGGVPASAKVPTLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPNWSALPRSVQDQKKGTSGATAEKGAEEDEEEVEECEPQTLPASPASVFNPPLQQPQTSRVLATLRGQVLLSKNVGVASGQWW------RRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICP---------QHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL-CR 441          

Query:  191 LILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPL-FGWKQKYE---IGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRN------------------------------SFPGIPDCXXXXXXXXXXXXXHSTTIR--VLLSASRDTLTKRWKDIMHSSKRSSQ--SEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR 1390
            LIL T FGN LVIL+V+ ++ L+ P N+ +V+LA +D+LVA L++P +   +L GYW F    C+ ++  DVL CT+SI++LCAIS+DRY  +++  +Y +KR  R +  ++   WL++A+IS+PPL +   Q+ E   + QC  +    Y + ++ G+F+ P +IMI++Y RIY IAK S      L + RGS   +    H       +S       +  S+   +  H           T +   +  L      L R+                              + P  P            +S+   T+R  VLLS +    + +W       +R +Q   E +  F L V++G F +CW PFF    L  I               +P  + + F W+GY NS LNP+IY  FN++FR  F+ IL CR
Sbjct:   27 LILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPHGLPQCELNQEAWYILASSIGSFFAPCLIMILVYLRIYVIAKRSHCRG--LGAKRGSGEGESKKPHPAAGGVPASAKVPTLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPNWSALPRSVQDQKKGTSGATAEKGAEEDEEEVEECEPQTLPASPASVFNPPLQQPQTSRVLATLRGQVLLSKNVGVASGQWW------RRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICP---------QHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL-CR 446          

Query:  116 NVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQL-KGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQ-CIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAA 727
            NVS       Y    +VV+G +  ++ L T  GN LV++SV   K+L+ P+N LIV+LA++D+ VA+ V+P  ++  L  G W+F    C+ FI  DV+ CTASI+ LC ISIDRYL IT+P  Y  ++N + M  M+   WL+SA I++PPLFGW Q     + C+ S   GY IY+T  AFYIP  +M+ +Y +IY+ A+ SAA
Sbjct:   69 NVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAA 274          

Query: 1094 IMHSSKRSS--QSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFV 1480
            + H  K  S  + E KA  TLG+I+G F +CWLPFF++    P    I G   +     IP  V    LWLGY NS +NP IY  FN++ RT ++ +L C+ R +N ++ S + M +  +  +  + S FV
Sbjct:  312 LKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPF---ICGTSCSC----IPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKL-SAAGMHEALKLAERPERSEFV 434          

Query:  101 EIAMANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIA-----KNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRH---SCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CRK 1399
            E       N T  S   F+ +V+  ++   LI     GN  V+ ++ L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    ++ L+WL+  LISIPP+ GW+    + +   C  S   GY IY+TFGAFYIP ++M+VLYGRI++ A     K     + +    R  +S  P    S N      +      +     +              CT   +R       L + E   V +S   +P                 +    +  A      K  ++     K +   E K + TLG+IMG F +CWLPFFIV ++ P  +         +   +P  +  +  WLGY NS LNP+IY  FNK+F+  FK+I+ C+ CR+
Sbjct:   16 EGPFGTRGNATGISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKAERKGADARSGVSPAPQPRKSVNGEPGGREWRQGPGSKAGGPL--------------CTNGAVRRGDDGAALEVIEVHRVGSSKEHLP---------------LPSEAGAIPCAPASFEKKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCE---------SSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIVRCKFCRR 422          

Query:  101 EIAMANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIA-----KNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRH---SCQLTLPEKRLVRNSFPGIP-DCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CRK 1399
            E     + N T  S   F+ +V+  ++   LI     GN  V+ ++ L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    ++ L+WL+  LISIPP+ GW+    + +   C  S   GY IY+TFGAFYIP ++M+VLYGRI++ A     K     + +    R  +S  P    S N      +      +     +              CT   +R       L + E   V +S   +P  C                    +  A      K  ++     K +   E K + TLG+IMG F +CWLPFFIV ++ P  +         +   +P  +  +  WLGY NS LNP+IY  FNK+F+  FK+I+ C+ CR+
Sbjct:   16 EGPFGTLGNATGISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKAERKGADARSGVSPAPQPRKSVNGEPGGREWRQGPGSQAGGPL--------------CTNGAVRRGDDGAALEVIEVHRVGSSKEHLPLPCEAG----------------AIPCAPASFEKKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCE---------SSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIVRCKFCRR 422          

Query:  122 SNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISST---KHNINSNIYRSCTTTDLRHS---CQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CRK 1399
             N+T+ S   F+ +V+  ++   LI     GN  V+ ++ L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    ++ L+WL+  LISIPP+ GW+    + +   C  S   GY IY+TFGAFYIP ++M+VLYGRI++ A+         K++R    K   T          + S    + S + Q  S    +   N  +   CT   +R       L + E   V NS   +P      + +   +              R+   KR        K +   E K + TLG+IMG F +CWLPFFIV ++ P  +         +   +P  +  +  WLGY NS LNP+IY  FNK+F+  FK+I+ C+ CR+
Sbjct:   23 GNVTSISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIR-----KTVRKVEKKGAGT-------SLGTSSAPPPKKSLNGQPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYAPACLERKN-------ERNAEAKR--------KMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCE---------SSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR 422          

Query:  122 SNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHS---CQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CR 1396
             N T  S   F+ +V+  ++   LI     GN  V+ ++ L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    ++ L+WL+  LISIPP+ GW+    +    +C  S   GY IY+TFGAFYIP ++M+VLYGRI++ A+           IR ++ K        +    S+    +S           +   N  +   C    +R       L + E   V NS   +P             S+   T  V     R    K  +      K +   E K + TLG+IMG F +CWLPFFIV ++ P  +         +   +P+ +  +  WLGY NS LNP+IY  FNK+F+  FK+I+ C+ CR
Sbjct:   23 GNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAAR---------FRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLP-----------LPSESGATSYVPACLER----KNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCE---------SSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR 421          

Query:  122 SNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIA-----KNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRH---SCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CRK 1399
             N T  S   F+ +V+  ++   LI     GN  V+ ++ L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    ++ L+WL+  LISIPP+ GW+    + +   C  S   GY IY+TFGAFYIP ++M+VLYGRI++ A     K    ++      R   S  P    S N    S    +  ++     +              C    +R       L + E   V NS   +P             S+   T     S  R    K  ++     K +   E K + TLG+IMG F +CWLPFFIV ++ P  +         +   +P  +  +  WLGY NS LNP+IY  FNK+F+  FK+I+ C+ CR+
Sbjct:   23 GNTTGISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGAL--------------CANGAVRQGDDGAALEVIEVHRVGNSKEHLP-----------LPSEAGPTPCAPASFER----KNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCE---------SSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 422          

Query:  110 MANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFVAACEDRKHSWRYNSVNYTEKK 1543
            MANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNSSYKSSQSDIQSQTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCRNKNNRNSRNSSKHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFVAACEDRKHSWRYNSVNYTEKK
Sbjct:    1 MANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNSSYKSSQSDIQSQTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCRNKNNRNSRNSSKHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFVAACEDRKHSWRYNSVNYTEKK 478          

Query:  110 MANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFVAACEDRKHSWRYNSVNYTEKK 1543
            MAN+SN TN  KY F NE++LGIVFC+LILGT  GNGLVILSV+LAKRLQTPNNILIVNLA+SDMLVALLVLPLATIYQLKGYWMFNEIVCDFFI CDVLLCTASILNLCAISIDRYLVITKPFQYI KRNN+LMVTMVG+SWL SALISIPPLFGWKQK+E+GQCIYSD LGYQIYATFGAFYIPSIIMIVLYGRIYQIAK+SAAMDS LKSIRGSI KDPMTIHSCNSSYKSSQSDIQSQTSFS  ISS +HNINSNIYRSCTTTDLRHSCQLTLP+KRLVRNSFPGI DC+NK+NRNSR++SKHSTTIRVLLSASRDTLTKRWK+I+HSSKRSSQSEGKAIFTLGVIMGCFCICW+PFFI+QIL PIFKIIHG+  +A L +IPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLST +A+ E+RK SWRYNSVNYTEKK
Sbjct:    2 MANISNYTNVQKYIFINELILGIVFCILILGTVIGNGLVILSVVLAKRLQTPNNILIVNLAISDMLVALLVLPLATIYQLKGYWMFNEIVCDFFIVCDVLLCTASILNLCAISIDRYLVITKPFQYITKRNNKLMVTMVGISWLASALISIPPLFGWKQKFELGQCIYSDSLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKHSAAMDSHLKSIRGSICKDPMTIHSCNSSYKSSQSDIQSQTSFSGHISSARHNINSNIYRSCTTTDLRHSCQLTLPDKRLVRNSFPGITDCQNKSNRNSRSNSKHSTTIRVLLSASRDTLTKRWKEIIHSSKRSSQSEGKAIFTLGVIMGCFCICWMPFFIIQILTPIFKIIHGHNPSAKLFTIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTTIASGEERKQSWRYNSVNYTEKK 479          

Query:  143 KYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKG-YWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFVAACEDRKHSWRYNSV 1525
            +Y    E +L ++F +LI GT  GN LVI ++IL K+LQ P+N LI++LA SD LVA   LPL    QL+G +W F+E  CD FIC DVLLC++SILNLCAISIDRYL+ITKP QY ++R  + M  M+ L W +S LISIPP+ GWK+ +  G+CIYS+ LGYQIYAT GAFYIP IIM+VLYGRI+++ ++    D++L       + D + +   N                          +  NI +  + +D   S    +  K+L                                +S +++   K++K     +++++ +E KAI TLGVIMGCF ICWLPFF++Q++ P+ K+ + + +    L I Q + ++FLWLGY NSFLNPIIY KFN+EFRTPFK IL C+C  +NA IRSE+Y +Q G         + +  C  +++ +  N++
Sbjct:   27 RYNSTIEHLLIVLFTLLIFGTLGGNCLVISAIILVKKLQIPSNFLILSLAASDTLVAFF-LPLVAFIQLRGGHWPFSETFCDIFICLDVLLCSSSILNLCAISIDRYLIITKPLQYGSRRTLKQMFLMILLVWFLSGLISIPPVIGWKEGFIPGKCIYSENLGYQIYATCGAFYIPLIIMLVLYGRIFKLTQSMVKKDAKLHKRASRYASDVLKMPDLNDDSV----------------------VKENICKRLSLSD--QSSNDWMDSKKLA-------------------------------ISNAKEEFIKQYK----KTEKANYAENKAITTLGVIMGCFTICWLPFFVIQLIKPLLKVANIDSN----LYISQWIQDMFLWLGYLNSFLNPIIYAKFNREFRTPFKLILLCKCVGINAVIRSEAYTQQYG---------SRIPPCSSKRNKYVQNTI 415          

Query:  167 VLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKN-----------SAAMDSQ---------------------LKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYR------SCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIG 1444
            ++G +  ++ +GTA GN LVIL+V L K+LQTP+N LIV+LA SD+LV +LVLP + I  LKGYW FNE +CD +I  DVL+CTASILNLCAISIDRYLVIT+PF Y++KR    M+ M+  +W++SALISIPP  GWK  +E+ +C YS  +GYQIYATF AFY+P ++MIVLYGRI+++A+            S+A D+Q                     L  +  + S+D    H   ++ + +  +    T  +     T+ +IN+   R      S TTTDL H+ +     KR  ++S                 +  + +   V+     DT      D+     R S ++ K I TLGVIMGCFC+CWLPFFI+Q+L  +      N  N     IP       LWLGY NSFLNPIIY K+N+EFR PFK IL C+CR +NAR+RS ++  + G
Sbjct:   61 IIGFILVLIAVGTAGGNFLVILAVALVKKLQTPSNFLIVSLAFSDLLVGILVLPFSIIDALKGYWPFNEPLCDMYISFDVLMCTASILNLCAISIDRYLVITRPFTYVSKRTPCRMLQMIAAAWVISALISIPPNIGWKTPFEVCKCEYSKNVGYQIYATFCAFYLPLLVMIVLYGRIFKLAREMSRAEHRQMVASSAEDAQAVVDDSKPENVAICNKEGEECLNRLSTTTSQDNNNPHP--NTAQPTAENGNRVTGTNNDTHETRSSINTTTERHGALNDSLTTTDL-HNGRSFSKSKRASKDS---------------STAFINRSNFHVV-----DTRQPSCTDLQRRKSRGS-ADSKVIKTLGVIMGCFCLCWLPFFIMQLLLALLTASGYNTENM----IPVEAFRFLLWLGYVNSFLNPIIYAKYNQEFRLPFKMILLCQCRNINARLRSATFSAEYG 496          

Query:  164 VVLGIVF---CVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKD---PMTI----HSCNXXXXXXXXXXXXXTSFSAQISSTKHN-----INSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIG 1444
            ++ GI+F    ++ + TA GN LVIL+VIL K+LQTP+NILI +LA SD  VALLVLP   I   +GYW FNE +CD +I  DVLLCTASILNLCAISIDRYLVITKP  Y ++R  + M  M+  +W+ SALISIPP FGWK+ ++   C YS  +GYQ+YATF AFY+P I+MI+LYGRI+++A+   +   Q K   G+ SK    P TI    HS     K+ Q    + T+    + S   +     IN+ + +   T D+   C+    +KRL                        +S + R LL+ S + +T       H  +    S+ K I TLGVIMGCFC+CWLPFF++Q+L  +      N +N     IP SV     WLGY NSFLNP+IY KF++EFR PFK IL C CR +NAR+R+  Y  Q G
Sbjct:   77 LITGIIFILSLIVAIATAGGNFLVILAVILVKKLQTPSNILIGSLAFSDFFVALLVLPFTIIDAYQGYWPFNEGLCDMYISFDVLLCTASILNLCAISIDRYLVITKPLTYASRRTPQRMAAMIATAWIGSALISIPPNFGWKEPFQKCACEYSKNVGYQVYATFFAFYLPLIVMIILYGRIFKLAR-EMSRSGQSKMTPGTSSKSTEVPETISNNSHSEPILDKNIQELQITSTNIPEYVQSDDEHIVTNAINNGVKKDGDTNDI---CETIENDKRL------------------------NSYSSRKLLTDSMN-VTNELSREAHGRRSRGNSDTKVIKTLGVIMGCFCLCWLPFFMIQLLLALLSAAGYNTANM----IPVSVFRFLQWLGYVNSFLNPLIYAKFDREFRGPFKMILLCHCRNINARLRAVHYSAQYG 485          

Query:  116 NVSNIT--NHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYE--------IGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTT-TDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CR 1396
            NVSN T    ++   + +V   ++   LIL + FGN  V+ ++ L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  D+L CT+SIL+LCAI++DRY  IT P  Y+ KR  +    ++G++WLV   ISIPP+   K + +           C+ S    Y IY+TF AFYIP I+M+VLYGRI++ A+         K++R S     +T+                    + ++ S + ++       C+     RH    +L    +V    PG             +    +   +V L  +R       K+     K +   E K + TLG+IMG F +CWLPFFI  ++ P                +P  + ++  WLGY NS LNPIIY  FNK+F++ FK+I+ C  CR
Sbjct:   20 NVSNGTAPERAEVPLSYQVSTSVLIGALILCSVFGNSCVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMACLYQVLDRWTLGQVTCDIFISLDILCCTSSILHLCAIALDRYWAITDPIDYMKKRTLKRAAVLIGVTWLVGFSISIPPMLIMKSQPKSKAEDIANPEACMISHDPWYTIYSTFCAFYIPLILMLVLYGRIFKAARFRIR-----KTVRKSEKVKCLTVSP------------ALFKKSNGELKSWRSSVEPKPIADCSNGAAKRHDDGESL---EIVEEVQPG---------GAKSSLPLPNAPGQVPLFENRHE-----KNTEAKRKLALARERKTVKTLGIIMGTFILCWLPFFIKALVMPF----------CPSCQMPVWLMDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKCHFCR 414          

Query:  188 VLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKY---EIG--QCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSA--AMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSS---QSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            ++I+ T  GN LVI++V+ ++ L+ P N+ +V+LA +D+LVA L++P +   +L G+W F  + C+ ++  DVL CT+SI++LCAIS+DRYL I++   Y A+R  R +   + + WL+SA+IS PPL    +K    E G  QC  ++   Y +Y+T G+F+ P +IMI++Y RIYQIAK           K I  S  + P T  + N+               +A     K   N+N   S + +D          E+  V    P  P        +S  + +    +      +R    K  +D   +S R       E +  F L V++G F +CW PFF    L  +              ++P+ + + F W+GY NS LNP+IY  FNK+FR  FK+IL
Sbjct:   29 LMIVFTIVGNILVIIAVLTSRSLRGPQNLFLVSLAAADILVATLIIPFSLANELMGFWYFKSVWCEIYLALDVLFCTSSIVHLCAISLDRYLSISRAVTYGAQRTPRRIKCAILIVWLISAVISFPPLLSMNKKKGTDEAGCPQCELNNERWYILYSTIGSFFAPCLIMILVYMRIYQIAKQRTRCPPGEPRKEIPASAKQQPATTPTTNNLLPPPSLG-------TALTPPDKKPDNNNGESSTSDSDT---------EQGGVGTEMPMTPSGEPSAGIHSPATIQKYRDMIATAKGTRLASRKSKQDGTPNSARRKAMVNREKRFTFVLAVVIGVFVVCWFPFFFSYSLQAVC---------PRTCNLPEPLFKFFFWIGYCNSCLNPVIYTIFNKDFRRAFKKIL 411          

Query:   83 YSKSIFEIAMANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVT-MVGLSWLVSALISIPPLFGWK--QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTS-----------FSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNS-------FPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFC 1387
            Y++S  E  +   ++     K+ +       ++  +LI    FGN LV ++V   K LQT  N LIV+LAV+D+LVA LV+P     ++ G W F+ I CD F+  DV++CTASILNLCAISIDRY  +  P  Y  + ++R  VT M+ + W++S  IS P LFG    +  +   C+ ++   + +Y++  +FY+P II +++Y +IY + +      S  ++   S ++   T+  C          +  +++           F  ++ +   ++ ++   +    + R   Q    +  L+  S        P +P+   K +RN         T       S    T+      +  K S Q E KA   L +++G F ICWLPFFI  I+N             T  ++P  +   F WLGY NS +NPIIY  FN EFR  F +IL C
Sbjct:    9 YNQSFLENGLDGFNSTDGGRKHQYN---YYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWRFSTIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSRRRVTVMISVVWILSFAISCPLLFGLNNTESRDDALCVIANP-AFVVYSSIVSFYVPFIITLLVYVQIYVVLRKRRKRVSTKRTFPSSTAERGTTLKKCTHPDDVKLCTVIVKSNGNFPVNNKNVIFIKEVVNNADDVQADEVTNPEPLNQRTLEQTGASQHGLLLVSTHSETEVLPTVPEAPIKPSRNGNTGDAPRVTKAFETQVSPSGKTQSSVKSFNKRKFSQQKEKKATQMLAIVLGVFIICWLPFFITHIVN-------------TYYNVPAELYTAFTWLGYVNSAVNPIIYTTFNIEFRKAFIKILHC 447          

Query:  173 GIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVT-MVGLSWLVSALISIPPLFGWK--QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKS-------IRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFC 1387
             ++  +LI    FGN LV ++V   K LQT  N LIV+LAV+D+LVA LV+P     ++ G W F+ I CD F+  DV++CTASILNLCAISIDRY  +  P  Y  + ++R  VT M+ + W++S  IS P LFG    +  +   C+ ++   + +Y++  +FY+P II +++Y +IY + +      S  ++       +       P  +  C    KS+ +   +  +   QIS+ +      + +            L L          P +P+   K +RN         T       S    T+      +  K S Q E KA   L +++G F ICWLPFFI  I+N             T  ++P  +   F WLGY NS +NPIIY  FN EFR  F +IL C
Sbjct:   26 AMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWRFSTIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSRRRVTVMISVVWILSFAISCPLLFGLNNTESRDDALCVIANP-AFVVYSSIVSFYVPFIITLLVYVQIYVVLRKRRKRVSTKRTFPKFNVHLNSPKCTHPDDVKLCTVIVKSNGNFPVNNKNVVCQISADEVTNPEPLNQRTLEQTGASQHGLLLVSTHSETEVLPTVPEAPIKPSRNGNTGDAPRVTKAFETQVSPSGKTQSSVKSFNKRKFSQQKEKKATQMLAIVLGVFIICWLPFFITHIVN-------------TYYNVPAELYTAFTWLGYVNSAVNPIIYTTFNIEFRKAFIKILHC 426          

Query:  164 VVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQC-IYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQS-VSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR 1390
            ++L +   VL + T   N LVI ++I+ ++L  P N LI +LAV+D+LVA+LV+P + +Y +K  W+  +++C+ ++  D+  CT SIL+L AI++DRY  IT   +Y  KR +     M+ + WL+S L+S+PPL  W+Q  +  QC I  D + + +Y+TFGAFYIP I++++LY +IY+ AK        L   RG+   +                               K  +N ++   C+  + +    L+ PEK L   S  G                      RV ++A       R +  +   + S   E KA  TLG+I+G F ICWLPFFI +++            N     +P S ++    WLGY NS +NP+IY  FN++F+  F++++ CR
Sbjct:   30 ILLSLTLSVLAVLTTAINSLVITAIIVTRKLHHPANYLICSLAVTDLLVAVLVMPFSIVYIVKDTWVMGQVMCNIWLSVDITCCTCSILHLAAIALDRYRAITDAVEYSRKRTSLRAAVMICVVWLLSILVSLPPLL-WRQNKDTDQCLIKHDHIAFTLYSTFGAFYIPLILILILYYKIYRAAK-------ILYHKRGTSRLN-------------------------------KTEMNGHMIPKCSDREQQSPDTLSPPEKSLSEPSTEG---------------------DRVRITARSPNFQSRRERSIKRQRISGTRERKAATTLGLILGAFVICWLPFFIQEVI-----------INTCSTCVPSSEIANFLTWLGYLNSLINPLIYTIFNEDFKKAFQKLVKCR 369          

Query:  155 ANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK---QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAK 715
            A  V+  +    LIL   FGN  VI ++ L + LQ   N LI +LAV+D+LV++LVLP+A +YQ+   W   ++VCD FI  DVL CT+SIL+LC I++DRY  IT P  Y+ KR  R  V M+ L+WLV   ISIPP+ GW+    + +   C  S   GY IY+TFGAFYIP I+M+VLY RI++ A+
Sbjct:   34 AYTVISSLCLTALILCAIFGNSCVIAAIALERTLQNVANYLIGSLAVTDLLVSILVLPMAALYQVLDRWTLGQVVCDIFIALDVLCCTSSILHLCVIALDRYWAITNPIDYVNKRTPRRAVIMISLTWLVGFSISIPPMLGWRTPEDRADPNACKISQDHGYTIYSTFGAFYIPLILMLVLYSRIFRAAR 223          

Query: 1265 IPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR-CRK 1399
            +P  V  +  WLGY NS LNPIIY  FNK+F+  FK+I+ C+ CR+
Sbjct:  343 LPPGVFAVINWLGYSNSLLNPIIYAYFNKDFQNAFKKIIKCKFCRQ 388          

Query:  146 YAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQ---KYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAK 715
            Y  A    LG +    I G AF    V+ ++ L + LQT  N LI +LAV+D+LV++LVLP+A +YQ+ G W   + VCD FI  DVL CT+SIL+LCAI++DRY  IT P  Y+ KR  R    M+ ++W+V   ISIPP+ GW+Q   + +   C  S  LGY IY+TFGAFYIP ++M+VLYG+I+  A+
Sbjct:    1 YQTATSSALGALIACSIAGNAF----VLAAIYLERSLQTVANYLIGSLAVTDLLVSVLVLPVAALYQVLGRWTLGQAVCDAFIALDVLCCTSSILHLCAIALDRYWAITDPVDYVNKRTPRRAALMIAITWVVGFSISIPPMLGWRQAEDRADPDACNISQHLGYTIYSTFGAFYIPLVLMLVLYGKIFSAAR 189          

Query:  215 NGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYS-DCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKN 718
            N LVI ++   ++L+ P N LI +LAV+D+LVA LV+P+A  Y + G W     +CD ++  DV  CTASIL+LCAI++DR+  IT   +Y  KR       M+  SWL++A IS+PPLF  ++     +CI   D + Y IY+TFGAFY+P  +++ LY RI++ AK 
Sbjct:   65 NALVIAAISATRKLRQPANYLIGSLAVADLLVAALVMPVAAAYVVTGEWALGGALCDLWLSLDVTCCTASILHLCAIALDRFWAITDAAEYAHKRTPGRAALMIAASWLLAACISVPPLFWRRRDPAKPRCIIEHDHVLYTIYSTFGAFYVPLALLLALYCRIFRAAKR 233          

Query: 1115 SSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            S   E +A  TLG+I+G F +CWLPFFI ++      +++  KS A    +   V++L  WLGY NS +NP+IY  FN++F++ F++++
Sbjct:  343 SGSRERRAAKTLGLILGAFVVCWLPFFIKEL------VVNLCKSCA----VSPEVADLLTWLGYMNSLINPLIYTMFNEDFKSAFRKLV 421          

Query:  116 NVSNITNHS---KYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQK-----YEIGQ--CIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAA 727
            N SN T+     +Y+    + L  +  +L+  T FGN LVI++V+    L+ P N+ +V+LA +D+LVA LV+P +   +L GYW F  + C+ ++  DVL CT+SI++LCAIS+DRY  +++  +Y  KR  R +  ++ + W ++  IS+PPL    QK      E+G+  C  +    Y + +  G+F+ P +IM+++Y RIY + K  AA
Sbjct:   33 NSSNGTDEKLGWEYSVLAGLGLSSLVLILVFATVFGNCLVIIAVLTRPSLKAPQNLFLVSLATADILVATLVIPFSLFNELMGYWYFGRVWCEIYLALDVLFCTSSIVHLCAISLDRYWSVSQAVEYNIKRTPRRIKRIIVIVWFIAIAISLPPLISMNQKNRQQQEEVGRPNCELNTNTWYILGSCIGSFFAPCLIMVLVYARIYHLVKWRAA 246          

Query: 1079 KRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            +R        K +   E +  F L V++G F ICW PFF    L+ +         +    +IP+++ + F W GY NS LNP+IY  FN++FR  FK+IL
Sbjct:  362 ERQNKARERRKIAQARERRFTFVLSVMIGVFVICWFPFFFTYSLSAL--------CSPESCAIPETLFKFFFWFGYCNSCLNPVIYTVFNRDFRRAFKKIL 454          

Query:  191 LILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFG--------WKQKYE-------------IGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSA 724
            +IL T FGN LV ++V  +K L+   N+ +V+LA +D+LVA LV+P +   +L GYW+F    C+ ++  DVL CT+SI++LCAIS+DRY  +T+  +Y  KR  R +   + + W+++ALIS PPL G         + +++             +  C  ++   Y + +   +F+ P +IM+++Y RIYQ+AK  A
Sbjct:   43 IILVTIFGNSLVAIAVFTSKSLKAAQNLFLVSLAAADILVATLVMPFSLANELMGYWVFGSFWCEMYLALDVLFCTSSIVHLCAISLDRYWSVTQAVRYNMKRTPRRVKRAIVIVWVIAALISFPPLVGTGRPPANIHRHRHQGSGRNASSSPSSVLPTCKLNEETWYVLSSCTASFFTPCLIMLLVYARIYQVAKGRA 241          

Query: 1097 MHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCR 1396
            M   K ++  E +  F L V+MG F  CW PFF    L    KI   +         P+ + + F W GY NS LNP+IY  FN++FR  FK IL CR R
Sbjct:  378 MARRKLTAAREKRFTFVLAVVMGVFVACWFPFFFSYSLT---KICEAS------CKPPEYLFKFFFWCGYCNSSLNPLIYTVFNQDFRRAFKNIL-CRRR 467          

Query:  104 IAMANVSNIT--NHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLP--LATIYQLKGY-WMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDC-LGYQIYATF---GAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDI----MHSSKRSSQSEG-------KAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYF-----NSFLNPIIYVKFNKEFRTPFKEILF 1384
            I + N +NIT    +K +  + +       +++L T  GN LV  SV   +RL++P N L+V+LAVSD+LV  L LP  LA +   + +        C F+I  D+L   AS++NL  IS DR L I +P +Y  K  ++  + ++ + W+ +A  +      W+ +  I    Y  C +  ++Y T     AF+ P +I+I+ YG + Q+A            IR ++                             Q+   K  I  N+     + +   S + +L    ++R                              L  SR +  +  KDI     H+  R+  S         KA  TL V++G F +CW PFF++ +        + +        IP +V  + L +  +     NS  NPIIY  FN+EFR  F +I +
Sbjct:    2 IPVGNNTNITMPAGAKNSVGSTIASACFIVIVMLLTIMGNLLVCYSVFYYRRLRSPTNYLVVSLAVSDLLVGTLSLPFRLAQLLNEENWPSHLGREGCQFWIWVDMLCSGASMVNLAGISFDRLLAIKQPLRYREKMTSKRALILILVVWIYAASCAFLSFVEWEGESTIAA--YPQCGIRARVYITLMALAAFFCPLLIVIICYGMVLQVA------------IRHAL-----------------------------QVQKEKEQIALNVSPEPNSNNHEESGETSLASPPVIR------------------------------LKTSRSSSHR--KDINFANGHAKHRNPASSTFHIMKQIKATKTLAVVVGVFILCWFPFFVIFV-----TFQYCDTECFGEERIPPAVKRVLLIIFVYVLPVSNSAANPIIYSCFNQEFRVAFLKIFY 373          

Query:  191 LILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQL--KGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQ----KYEIG-QCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSA------AMDSQLKSIRGSIS 766
            ++L T +GN +V+L+V+L  R++T  N  +V+LAVSD+LVA L LP   I+Q      W      C  +I  D++ C ASI NL  IS+DR++ I  PF+Y A       V ++G  W++S  + +  L  W +     + I  QC   D + Y + +  G F++P  I++++YG+++ +A N A        DS+ +  R SI+
Sbjct:    8 ILLVTFYGNFMVVLAVVLFHRMRTITNYFVVSLAVSDLLVATLSLPF-RIHQTTHNTAWCLGLEACVAWIVVDIICCGASIWNLAMISVDRFIAIVMPFRYHALMTPMTGVCLIGAVWILSMGMGMLSLINWTELGSPHFHIEVQCRKFDPVYYTVVSVVG-FFLPLFIVLLMYGQVFVVAMNQARAVAALQTDSKRRGRRSSIN 210          

Query: 1091 DIMHSSKRSS---QSEGKAIFTLGVIMGCFCICWLPFFI---VQILNPIFKIIHGNKSNATLLSIPQSVSELFLW-LGYFNSFLNPIIYVKFNKEFRTPFKEI 1378
            D     +RSS     E KA   L +++GCF +CW PFF+   V +  P     H            + ++  F++ L   NS LNPIIY  FN++FR  F +I
Sbjct:  199 DSKRRGRRSSINLVKEVKAAKILAIVVGCFVVCWFPFFVLTLVSLWEP-----HALSKETISKDTARGITLTFVYVLPVLNSTLNPIIYALFNRDFRRAFGKI 296          

Query:  188 VLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSIS 766
            +LI+GT FGN LV  +  L + L+T  N  +V+LA++D+LV  + +PL   Y +  +   N  +   ++C D+   TASI+NL  IS+DR+  IT PFQY  K   +     +   WL +  +S      +       +  +S   GY  +    +F++P  +MI  Y RI+ +A+  AA   +L S+R  I 
Sbjct:   10 LLIVGTIFGNSLVCAAFYLFRDLRTVTNYFVVSLAIADLLVGFVSMPLWFTYLVFQWPPQNSEIYALWLCFDIATATASIMNLAVISVDRFYAITLPFQYSQKITKKRACLAIVFVWLYAFAVSSSRAISFAIPSRESRAQFS--FGYTFFVATASFFVPLPVMIYCYTRIFSVARVQAAKIRELDSVRSFIE 200          

Query: 1061 SRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEIL 1381
            SR  LT   +      +R+  ++ KA  TL ++MG F +CW P+ I  +L          +   TL       ++   WL Y NS LNPIIY   N+ FR  FK +L
Sbjct:  207 SRPVLTS--QSSFRLQRRALSTDIKAAKTLAIVMGAFLLCWAPYIIALLLEVSCPRCVPFQDKYTL-------AKAVKWLVYSNSALNPIIYTALNRAFRDAFKRVL 304          

Query:  179 VFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQL-----KGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSD-CLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRH-SCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKE 1354
            V  +L+L    GN LV  +V + +RL      L+ +LA++D++V + +LPL+  Y +      G W F+ +VC      +   C AS+ NLCA+S DRY+ +T P  Y  + ++  +   + + W+VS  +S   +    +   +  C  +   + Y + +    F IP I ++   GRI  IA+      +QLK I+  +   P                       S + SS+K    +    S T T+L   + +   PE+ L       IP+                         S+    +R++            E K      ++ G F +CW P F+  +++   +         T++SI        L LGY NS  N  IY  FN+E
Sbjct:    1 VLLILMLVIIVGNTLVFRTVFVTRRLHFSAFYLVASLAIADLMVGVSLLPLSIAYTIIGEMKGGEWSFSPVVCHAGTLFNFWFCCASVFNLCAVSWDRYVAVTSPLLYTVRMDDAKVRWTIAVIWVVSLFMSFLIMVAVIESKTVFYCTATGLAVEYSLSSALVIFIIPLIFLVFANGRIMSIAR------AQLKKIKQQM---PYGYD-------------------SYEDSSSKSRTEAETLPSTTVTNLEQITTKPQEPEQNLDFQESIQIPN------------------------TSKKLYFQRFRR-----------EFKTFKLFVIVTGVFLVCWTPLFVTMVMSSFLR-------TWTMVSI----MHFALILGYANSACNVFIYSYFNRE 325          

Query:  212 GNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIY----QLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQC-IYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQI-AKNSAAMDSQ 739
            GN LV  +V +  RL +P   LIV++AV+D+LV L  +P++ +Y    ++ G W+  E VCD +I  +     ASIL+LCAI+ DRYL +T P QY+ +  N      +   W+ S + ++  ++G K       C I    +GY ++     +  P I ++ + G I+ + A++S  + SQ
Sbjct:   23 GNSLVFHTVRVTSRLHSPPFYLIVSVAVADLLVGLFAIPVSIVYLVSFEMYGKWILGETVCDVWILANFWFGGASILSLCAITRDRYLAVTSPLQYLRRMPNAHTAVQIVFCWVTSLVSAVITIYGLKTSPGRELCEIKGLTVGYALFNFVCLYVFPVIWILFVNGTIWSVAARHSRRIHSQ 204          

Query:  161 EVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWK--------QKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAK----------------------------NSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFC 1387
            +VV   +   LIL   FGN  V+ +++L + LQ   N LI +LAV+D++V++LVLP+A +YQ+   W   ++ CD FI  DVL CT+SIL+LCAI++DRY  IT+P  Y+ KR  R    ++ ++WLV   IS+PP+   +         +    QC       Y IY+TFGAFYIP  +M+VLYGRI++ A+                             +   D+Q KS + S+   P+ + S N                     + KH  +     S    ++  + +  LP         P  P                      L  +  D  T+  + I  + +R      K + TLG+IMG F +CWLPFFIV ++ P  +             +P+ + ++  WLGY NS LNPIIY  FNK+F++ FK+I+ C
Sbjct:   18 QVVTSFLLGALILCAIFGNACVVAAIVLERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNSWTLGQVPCDIFISLDVLCCTSSILHLCAIALDRYWAITEPIDYMKKRTPRRAAVLISVTWLVGFSISVPPMLVMRSQPGSMAEDRANPKQCKIRQDPWYTIYSTFGAFYIPLTLMLVLYGRIFKAARFRIRRTVRKTEKKKVADSCLAISPSLFHKTPHGDAQGKSWKRSVEPRPLALPSVN--------------------GAVKHAEDGE---SLEIIEVHSNSRGNLP--------LPNTPSTVP------------------LFESRHDKATEAKRKIALARER------KTVKTLGIIMGTFILCWLPFFIVALVMPFCQ---------ESCYMPRWLEDVINWLGYSNSLLNPIIYAYFNKDFQSAFKKIIKC 398          

Query:  161 EVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQ---KYEIGQCIY-SDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSA--QISSTKH---NINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCR 1390
            +V L ++  ++ L T   N  VI ++ L ++L TP N LI +LAV+D+LV++LV+P++ +Y +   W   +IVCD ++  D+  CTASIL+LC I++DRY  IT   +Y  +R  R    MVG+ W++S  IS+PPLF W+Q     E+ +C+  +D + Y +Y+TFGAFY+P++++I+LYGRIY  A             R  I K P     C+S  + + + +   ++ S+   ++ST H   +++S   RS  +    +S ++ L +  L R                              L A+R+             ++++++ G       +I+G F +CWLPFF+  ++  I K    +            + +LF WLGY NS +NP+IY  FN EF+  F++++ CR
Sbjct:   34 QVSLSVLLALVTLATVLSNAFVITTIFLTRKLHTPANFLIGSLAVTDLLVSILVMPISILYTVSKTWSLGQIVCDIWLSSDITFCTASILHLCVIALDRYWAITDALEYPKRRTMRRAAMMVGVVWVISISISMPPLF-WRQAKAHEELTECVVNTDQISYTLYSTFGAFYVPTVLLIILYGRIYMAA-------------RSRILKTP-----CSSGKRFTTAQLIQTSAGSSLCSLNSTSHQEAHLHSGSTRSGGSPLFMNSVKVKLADSVLERKR----------------------------LCAARE-------------RKATKTLG-------IILGAFIVCWLPFFVGTLVLAICKECWFHP----------ILFDLFTWLGYLNSLINPVIYTAFNDEFKQAFQKLIKCR 375          

Query:  152 FANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQ--KYEIGQC-IYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKR-SSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFK-IIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRC 1393
             A +  L +   ++   T   N  VI ++  +++L TP N LI +LAV+D+LV++LV+P++ +Y +   W   ++VCD ++  D+  CTASIL+LC I++DRY  IT   +Y  KR       M+  +W+++  IS+PP F W+Q    E+  C + +D + Y IY+TFGAFYIP++++I LYGRIY  A+      SQ K  +   S   +T                   S  +  S+T  N  +N   SC TT   +  Q                                    ++V +S           D +   KR S+  E KA  TLG+I+G + ICWLPFFI  +L P+     H           P+ + ++F WLGY NS +NPIIY   N++F+  F +++  RC
Sbjct:   11 LAFQAGLAVTLALITFATTLSNAFVIATIYQSRKLHTPANFLIASLAVTDLLVSILVMPISALYTVCQTWTLGQVVCDIWLSSDITCCTASILHLCVIALDRYWAITDAVEYSKKRTPARAAGMIATAWVIAISISLPPFF-WRQVKAEEVTSCNVNTDHIFYTIYSTFGAFYIPTLLLIALYGRIYVEARKRILKQSQNKPGKRLTSARLIT------------------NSPGSVASTTSLNYGTNDTSSCDTTSSANVSQ------------------------------------VKVTVS-----------DALLEKKRISAAREKKATKTLGIILGAYIICWLPFFIYTLLVPLCDSCFH-----------PE-LFDIFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFRC 351          

Query:   92 SIFEIAMANVSNITNHSKYAF---ANEVVLGI---VFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSC---TTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRK 1399
            S F + + NVS+  N +   F     EV   +   V  V+IL T  GN LVI++V+ ++ L+ P N+ +V+LA +D+LVA LV+P + + ++ GYW F    C F++  DVL CT+SI++LCAIS+DRY  +TK   Y  KR  + + +M+ + W++SA+IS PPL     K++  +C+ +D   Y I +   +F+ P +IMI++Y +IY++AK  +   S +   +  + + P    +C       +++  S  S  +Q        + ++  SC   + T  RH+      ++R V  S     DC    +           + R L            + + + +K +   E +  F L V+MG F +CW PFF    L+ I +             IP ++  LF W+GY NS +NPIIY  FN++FR  FK+I+ CR  K
Sbjct:    4 SHFNLLVENVSSDENATDAPFILPHTEVATALIILVVTVIILVTIVGNVLVIVAVLTSRALRAPQNLFLVSLASADILVATLVIPFSLVNEVMGYWYFGSTWCAFYLALDVLFCTSSIVHLCAISLDRYWSVTKAVSYNLKRTPKRIKSMIAIVWVISAVISFPPLL--MTKHDERECLLNDETWYIISSCMVSFFAPGLIMILVYCKIYKVAKQRS---STVFVAKNGLERQPSQSETCFVRKDRFEAESPSSQSSGSQQQRQGELDDIDLEESCYSSSDTKPRHN---RFTKRRKVEGS-----DCCPPQSCRLSW-----ASARALQPYPEQKHPPGRQQLANKTKVAQMREKRFTFVLAVVMGVFVLCWFPFFFTYTLHAICR---------DSCYIPGALFNLFFWIGYCNSSVNPIIYTIFNRDFRKAFKKIV-CRTSK 420          

Query:  137 HSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEI-GQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAK---------------NSAAMDSQLKSIRGSISKD-----P-------MTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLV----RNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLL----SASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILF 1384
            +S Y+        IV   +++ T  GN LVI++V++++ L+ P N+ +V+LA +D+LVAL+V+P +  Y+L G W+F+ I C+     DVL CTASI++LCAI++DRYL I++P  Y   R+ R + + + + WL++A++S PPL     K ++ G+C   D   Y +Y+T G+F+ P +IMI++Y RIYQIAK                +A  D+++KS+     KD     P        T+H+ + +  + +   +S T      S+   N   ++ ++     +  S   +  E + +    R    G P  + ++      ++  +++   LL    + +++T   R K +++  KR +         L V+MG F +CW PFF    L    K +   K       +P  +   F W GY NS LNPIIY  FN++FRT FK ILF
Sbjct:   19 NSTYSPQATAAFSIVMTSMMILTIVGNILVIIAVLMSRSLRGPQNLFLVSLAAADILVALIVVPFSMAYELLGCWVFSSIWCEIHKALDVLFCTASIVHLCAIALDRYLSISRPVSYGTTRSRRRIKSAIVMVWLIAAVVSFPPLLYLDTKDKVKGKCEPDDKPWYILYSTIGSFFAPCVIMILVYIRIYQIAKRHMHCPPGEKRRSFYGAATDDTEMKSLPEESQKDVGQRAPAAPELSLTTVHT-DCAQWNDKKPAESPTEGPPLFSTAVPNAARDLPKAEGEDAVHTSSSESDTELQSIEEGDRAGGGGSPKAQVQSPTCRYKNTIKTSSGTKLLPEDTAKTQETPISRHKAMINREKRFT-------LVLAVVMGVFVVCWFPFFFSYSL----KAVCPEK-----YQVPDPLFRFFFWSGYCNSCLNPIIYTIFNRDFRTAFKRILF 453          

Query:  110 MANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFVAACEDRKHSWRYNSVNYTEKK 1543
            MANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNSSYKSSQSDIQSQTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCRNKNNRNSRNSSKHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFVAACEDRKHSWRYNSVNYTEKK
Sbjct:    1 MANVSNITNHSKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNSSYKSSQSDIQSQTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCRNKNNRNSRNSSKHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIGEFRKISKLSTFVAACEDRKHSWRYNSVNYTEKK 478          

Query:  164 VVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLK-------------SIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNI-------------NSNIYRSCTTTDLRHSCQLTLPEKR---------LVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIG 1444
            +V+  V  +L +GT   N L+I +V L K+L+TP N+LI+NLAV+D+LV  LV+P A+IYQ+KGYW+F+EIVCD FI  DVLLCT+SILNLCAIS+DRYLVIT+PF+Y  KR  + M+ M+ L W  S LISIPPLFGW+QK     C YS+ LGYQIYATF AFY+P ++M+VLYGRI+++AK   A + + K             S RGS + D     +  +               S +I++   N                N++ +  ++D+  +    +  KR         +++  + GI D                       + + + L  +     H  +++S  E KA+ TLG+IMGCF ICWLPFF++QIL PI K+++   SN           ++F WLGY NSFLNP+IY KFN+EFR PF +IL C CR +NA +RSE+Y  Q G
Sbjct:   51 IVISTVLTLLSVGTCIDNCLMISAVALVKKLRTPCNMLILNLAVTDLLVGTLVIPFASIYQIKGYWIFDEIVCDIFILFDVLLCTSSILNLCAISVDRYLVITQPFKYAVKRTRKRMLCMILLVWTASGLISIPPLFGWRQKRHPYTCDYSEDLGYQIYATFIAFYLPLVVMLVLYGRIFRLAKAMVAAEIKNKINTDCSESITTSVSRRGSFTDDGEDTTTKGTLQVVGDFFKPISRRLSFRINTDNSNTIYNPVYDEMGLSPKKNVFFNRRSSDVSKTSLGNVNNKRRQVNPMDVPIIQIDYTGIKD----------------------ENQNSEYLQNKPMQNFHKPQKAS-VEAKAVRTLGIIMGCFTICWLPFFLMQILFPILKMLNIEYSNGAT----NICFQIFYWLGYTNSFLNPLIYAKFNREFRRPFCQILMCHCRHINAHLRSETYNDQYG 485          

Query:  143 KYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMTIHSCNXXXXXXXXXXXXXTSFSAQISSTKHNINSNIYRSCTTTDLRHSCQLTLPEKRLVRNSFPGIPDCXXXXXXXXXXXXXHSTTIRVLLSASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNS 1315
            KY    EV +G++  +L   T  GN L+I++V L K+LQTP+N+LIVNLA SD+LV+ +VLP A I+QLKG+W F+E +CD FI  DVLLCT SIL+LC ISIDRY  IT+P QY +KR    +  M+   W+++ LIS+PP  GWK+K+   +C YSD L YQIYATFGAFY+P  IM+ LYG+I  +AK  A +D + +S + S     +   + N                      T  N   ++ ++   + ++H                    D R  N+++   +     TI  L + +   L K+ K  + S  ++ ++ G     +G    C+C    PFFI+Q+  PI K + G   N     +P +V E+FLWLG F++
Sbjct:   48 KYTPTQEVFIGLILSILTFSTLVGNILIIIAVTLVKKLQTPSNLLIVNLATSDLLVSGIVLPFAIIFQLKGFWPFSEFLCDTFILSDVLLCTCSILSLCIISIDRYFAITRPLQYASKRTTGRISIMIVSVWVLAGLISVPPFIGWKEKFVKNECKYSDSLSYQIYATFGAFYVPLFIMLFLYGKILLLAKRIANLDLKQRSQKTSRRNSTVVFSNHN----------------------TTENRKPSLQQTMNCSFIQH--------------------DHRESNDKSEEMAFSKRYTITKLYNRTSMNLYKKSK--LSSEVKAIKTLG---IIMGCFTICWC----PFFIIQLTIPIAKAL-GQDPNF----VPPTVIEIFLWLGKFSA 382          

Query:  143 KYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQL--KGYWMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLK 745
            K++F  E+ L ++F V ++GTA GN LVI+SV + K+LQTP+N LIVNLA SD LV++LVLP A I+Q   +  W F+EI+CD FI  DV+LCT+SILNLCAISIDRYLVIT+P QY   R    +  M+ +SW+ SALISIPPLFGWK+ +  GQC YS+ L YQIYATFGAFYIP ++M++LYGRI+++A+  A  D+++K
Sbjct:   32 KFSFDFEMFLIVIFTVFVVGTAGGNLLVIMSVAIVKKLQTPSNFLIVNLACSDFLVSILVLPGA-IHQTINRSRWPFSEILCDVFISFDVILCTSSILNLCAISIDRYLVITRPLQYAVNRTPARISLMIAISWIASALISIPPLFGWKETFIPGQCSYSENLLYQIYATFGAFYIPLLVMLILYGRIFKLARVLAQNDAKMK 233          

Query: 1058 ASRDTLTKRWKDIMHSSKRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIG 1444
            +S++ L  R +     +K  S +E KAI TLGVIMGCF ICWLPFFI+QI  PI K+   N  N      P  + E+ LWLGYFNSFLNPIIY KFN+EFRTPFK+IL CRC  +NAR+RSE+++++ G
Sbjct:  285 SSQNKLNNRSR-----AKIKSSTETKAITTLGVIMGCFTICWLPFFIIQIAKPILKVASVNSVNY----FPIWLIEICLWLGYFNSFLNPIIYAKFNREFRTPFKQILLCRCSSINARLRSETFVQEYG 404          

Query:  140 SKYAFANEVVLGIVFCVLILGTAFGNGLVILSVILAKRLQTPNNILIVNLAVSDMLVALLVLPLATIYQLKGY-WMFNEIVCDFFICCDVLLCTASILNLCAISIDRYLVITKPFQYIAKRNNRLMVTMVGLSWLVSALISIPPLFGWKQKYEIGQCIYSDCLGYQIYATFGAFYIPSIIMIVLYGRIYQIAKNSAAMDSQLKSIRGSISKDPMT 781
             KY    EV LG++F V+++G   GN LVIL++ L K+LQTP+N LI++LA SD  V++LV+P+A   QL  + W F+E+ CDFFI CDVLLCT+SILNLCAISIDRYLVIT+P QY+ +R   L+   +  +W++S LISIPP+  WK+ +  G C  ++ LGYQIYAT GAFYIP IIM+VLY RI+++A+N A  D++ K   G ++ +  T
Sbjct:   30 EKYPVGMEVFLGMIFVVIVVGAIGGNFLVILAIFLVKKLQTPSNWLILSLAFSDFFVSVLVMPVAVYNQLMRFRWPFSELFCDFFIICDVLLCTSSILNLCAISIDRYLVITRPMQYVVRRTPLLIGGFIAGAWIISGLISIPPVIVWKEPFRPGTCQLTENLGYQIYATLGAFYIPLIIMLVLYYRIFKLARNMAQEDAKRKLGTGQMTDEEQT 244          

Query: 1109 KRSSQSEGKAIFTLGVIMGCFCICWLPFFIVQILNPIFKIIHGNKSNATLLSIPQSVSELFLWLGYFNSFLNPIIYVKFNKEFRTPFKEILFCRCRKLNARIRSESYMRQIG 1444
            K+ S +E KAI TLGVIMGCF +CWLPFFI+QIL PI  +   +K +     +P    ELFLWLGY NSFLNP+IY KFN+EFR PFK+ILF  C  +NARIR +++  Q G
Sbjct:  296 KKQSNNESKAITTLGVIMGCFTLCWLPFFIIQILKPILIV---SKVDHEKYLLPWCY-ELFLWLGYLNSFLNPVIYAKFNREFRNPFKQILFFHCININARIRVDTFAEQYG 403