WD_REPEATS_REGION domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015127 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 77.7962 bits (190), Expect = 2.501e-13 Identity = 155/790 (19.62%), Postives = 297/790 (37.59%), Query Frame = 3 Query: 1320 EQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHK---SGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSM-----------FNWLPLKMNNC--KVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLGTFYDE---SGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLH----IVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSII------TNNWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILG 3578 EQ T+F +EI+ L I+E L + D + + Q + L HI + + L+ H+ S L + + H Y+ ++ +L ++ + EL + L + I L++ + Q + +++L + +H S + P+ L P GKT LMC L A Q +L + + + RLLG S ++D +L+S+C Q+ + L P ++ + Q F ++ N + ++M WLPL NC +V + L + LD + + + LS + +I+ ++ R + ++L +++ +C G + + AR W S + L E RLE G+ ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG + G L+ H RYL ++A + L ++ + L L PL+ + Q ++F + N R++ +LP+HL+ S + LK + + WI I G+ +++ L A ++ P + L+ LQ C+ + + R T + + + +++ +W P L+P ++ P + + + +T + L I T G++ +WD + + ++ G Sbjct: 182 EQGATVFLREIQDLHKHILEDCALRMVDRLADGCLDADAQNLLSSLKSHITDMHP--GVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRELDTAGQEL--AWLYQEIRHH----LWQSSEVIQTFCGRQELLAR--------LGQQLRHDDSKQHTPL-VLFGPPGIGKTALMCKL--AEQMPRLLG--HKTVTVLRLLGTSQMSSDARGLLKSICFQVCLAYGLPLP-PAQVLDAHTRVVQF-----FHTLLHTVSCRNFESLVLLLDAMDDLDSVRHARRVPWLPL---NCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR-----DWTPPSKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLIT-----LPLVGKPLNLDRKVAPQPLWF---------SHTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCA----PHLDSPEV---------GLVREALQL-CRPAVELRGMERSLLYTELLARLHFFATSHPALVGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTG 908
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 77.411 bits (189), Expect = 3.247e-13 Identity = 155/790 (19.62%), Postives = 297/790 (37.59%), Query Frame = 3 Query: 1320 EQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHK---SGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSM-----------FNWLPLKMNNC--KVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLGTFYDE---SGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLH----IVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSII------TNNWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILG 3578 EQ T+F +EI+ L I+E L + D + + Q + L HI + + L+ H+ S L + + H Y+ ++ +L ++ + EL + L + I L++ + Q + +++L + +H S + P+ L P GKT LMC L A Q +L + + + RLLG S ++D +L+S+C Q+ + L P ++ + Q F ++ N + ++M WLPL NC +V + L + LD + + + LS + +I+ ++ R + ++L +++ +C G + + AR W S + L E RLE G+ ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG + G L+ H RYL ++A + L ++ + L L PL+ + Q ++F + N R++ +LP+HL+ S + LK + + WI I G+ +++ L A ++ P + L+ LQ C+ + + R T + + + +++ +W P L+P ++ P + + + +T + L I T G++ +WD + + ++ G Sbjct: 182 EQGATVFLREIQDLHKHILEDCALRMVDRLADGCLDADAQNLLSSLKSHITDMHP--GVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRELDTAGQEL--AWLYQEIRHH----LWQSSEVIQTFCGRQELLAR--------LGQQLRHDDSKQHTPL-VLFGPPGIGKTALMCKL--AEQMPRLLG--HKTVTVLRLLGTSQMSSDARGLLKSICFQVCLAYGLPLP-PAQVLDAHTRVVQF-----FHTLLHTVSCRNFESLVLLLDAMDDLDSVRHARRVPWLPL---NCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR-----DWTPPSKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLIT-----LPLVGKPLNLDRKVAPQPLWF---------SHTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCA----PHLDSPEV---------GLVREALQL-CRPAVELRGMERSLLYTELLARLHFFATSHPALVGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTG 908
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 77.411 bits (189), Expect = 3.247e-13 Identity = 155/790 (19.62%), Postives = 297/790 (37.59%), Query Frame = 3 Query: 1320 EQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHK---SGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSM-----------FNWLPLKMNNC--KVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLGTFYDE---SGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLH----IVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSII------TNNWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILG 3578 EQ T+F +EI+ L I+E L + D + + Q + L HI + + L+ H+ S L + + H Y+ ++ +L ++ + EL + L + I L++ + Q + +++L + +H S + P+ L P GKT LMC L A Q +L + + + RLLG S ++D +L+S+C Q+ + L P ++ + Q F ++ N + ++M WLPL NC +V + L + LD + + + LS + +I+ ++ R + ++L +++ +C G + + AR W S + L E RLE G+ ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG + G L+ H RYL ++A + L ++ + L L PL+ + Q ++F + N R++ +LP+HL+ S + LK + + WI I G+ +++ L A ++ P + L+ LQ C+ + + R T + + + +++ +W P L+P ++ P + + + +T + L I T G++ +WD + + ++ G Sbjct: 182 EQGATVFLREIQDLHKHILEDCALRMVDRLADGCLDADAQNLLSSLKSHITDMHP--GVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRELDTAGQEL--AWLYQEIRHH----LWQSSEVIQTFCGRQELLAR--------LGQQLRHDDSKQHTPL-VLFGPPGIGKTALMCKL--AEQMPRLLG--HKTVTVLRLLGTSQMSSDARGLLKSICFQVCLAYGLPLP-PAQVLDAHTRVVQF-----FHTLLHTVSCRNFESLVLLLDAMDDLDSVRHARRVPWLPL---NCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR-----DWTPPSKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLIT-----LPLVGKPLNLDRKVAPQPLWF---------SHTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCA----PHLDSPEV---------GLVREALQL-CRPAVELRGMERSLLYTELLARLHFFATSHPALVGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTG 908
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 77.411 bits (189), Expect = 3.247e-13 Identity = 155/790 (19.62%), Postives = 297/790 (37.59%), Query Frame = 3 Query: 1320 EQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHK---SGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSM-----------FNWLPLKMNNC--KVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLGTFYDE---SGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLH----IVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSII------TNNWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILG 3578 EQ T+F +EI+ L I+E L + D + + Q + L HI + + L+ H+ S L + + H Y+ ++ +L ++ + EL + L + I L++ + Q + +++L + +H S + P+ L P GKT LMC L A Q +L + + + RLLG S ++D +L+S+C Q+ + L P ++ + Q F ++ N + ++M WLPL NC +V + L + LD + + + LS + +I+ ++ R + ++L +++ +C G + + AR W S + L E RLE G+ ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG + G L+ H RYL ++A + L ++ + L L PL+ + Q ++F + N R++ +LP+HL+ S + LK + + WI I G+ +++ L A ++ P + L+ LQ C+ + + R T + + + +++ +W P L+P ++ P + + + +T + L I T G++ +WD + + ++ G Sbjct: 182 EQGATVFLREIQDLHKHILEDCALRMVDRLADGCLDADAQNLLSSLKSHITDMHP--GVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRELDTAGQEL--AWLYQEIRHH----LWQSSEVIQTFCGRQELLAR--------LGQQLRHDDSKQHTPL-VLFGPPGIGKTALMCKL--AEQMPRLLG--HKTVTVLRLLGTSQMSSDARGLLKSICFQVCLAYGLPLP-PAQVLDAHTRVVQF-----FHTLLHTVSCRNFESLVLLLDAMDDLDSVRHARRVPWLPL---NCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR-----DWTPPSKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLIT-----LPLVGKPLNLDRKVAPQPLWF---------SHTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCA----PHLDSPEV---------GLVREALQL-CRPAVELRGMERSLLYTELLARLHFFATSHPALVGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTG 908
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Human
Match: NWD1 (NACHT and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:27619]) HSP 1 Score: 77.0258 bits (188), Expect = 3.713e-13 Identity = 155/790 (19.62%), Postives = 297/790 (37.59%), Query Frame = 3 Query: 1320 EQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHK---SGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSM-----------FNWLPLKMNNC--KVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLGTFYDE---SGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLH----IVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSII------TNNWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILG 3578 EQ T+F +EI+ L I+E L + D + + Q + L HI + + L+ H+ S L + + H Y+ ++ +L ++ + EL + L + I L++ + Q + +++L + +H S + P+ L P GKT LMC L A Q +L + + + RLLG S ++D +L+S+C Q+ + L P ++ + Q F ++ N + ++M WLPL NC +V + L + LD + + + LS + +I+ ++ R + ++L +++ +C G + + AR W S + L E RLE G+ ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG + G L+ H RYL ++A + L ++ + L L PL+ + Q ++F + N R++ +LP+HL+ S + LK + + WI I G+ +++ L A ++ P + L+ LQ C+ + + R T + + + +++ +W P L+P ++ P + + + +T + L I T G++ +WD + + ++ G Sbjct: 182 EQGATVFLREIQDLHKHILEDCALRMVDRLADGCLDADAQNLLSSLKSHITDMHP--GVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRELDTAGQEL--AWLYQEIRHH----LWQSSEVIQTFCGRQELLAR--------LGQQLRHDDSKQHTPL-VLFGPPGIGKTALMCKL--AEQMPRLLG--HKTVTVLRLLGTSQMSSDARGLLKSICFQVCLAYGLPLP-PAQVLDAHTRVVQF-----FHTLLHTVSCRNFESLVLLLDAMDDLDSVRHARRVPWLPL---NCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR-----DWTPPSKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLIT-----LPLVGKPLNLDRKVAPQPLWF---------SHTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCA----PHLDSPEV---------GLVREALQL-CRPAVELRGMERSLLYTELLARLHFFATSHPALVGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTG 908
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Celegans
Match: T05C3.2 (pep chromosome:WBcel235:V:5493747:5503010:1 gene:WBGene00020254.1 transcript:T05C3.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T05C3.2) HSP 1 Score: 87.0409 bits (214), Expect = 1.452e-16 Identity = 123/618 (19.90%), Postives = 259/618 (41.91%), Query Frame = 3 Query: 1809 LSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLL--YETKVNLRIPEDIIGLKILLNQI--LLMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKMNNCKVIFS--TEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQK--FLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMN--NNYDRSVLFKSMD------------PDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLI----LSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSM-FSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSII 3572 L N+ + ++ G GKT+LM + A + + + + +V+ R LG S ++++ +L SVC Q+ Y+ + P ++ L +I L + ++I D ++ + D W P + +F+ T + IY + ++D L + P L ++++++S ++ Q + +++C FV W S S + L + L+ +I F R E Q G+ ++ L YIS +G+S E+ D+++ DD + F +L +S +R ++L +L + G+ ++ W H + A+ RY + + H ++ Y++ + + M D +P P ++F ++ H ++N R++ +LP+HL++S L +C+F++ ++ + F + +I + A + D+E + L + LS L NP + ++L R+ +V ++ ++ L K + +P+ +C +P + FSL F L+ + KL ++T ++ +WD S ++ ++ Sbjct: 453 LGNSTLPIILQGENGCGKTSLMAKI--ATKIREWYDNSCEPVVLLRFLGTSPDSSNIAPLLTSVCDQIASNYDESLKNSSPTELSKLFQHFKKITNLATREKPLVIIFDSLDLLSRI--DGAHELLWFPPSLPPFVKLFASLTPGGSLIYSKMQRLIEDKRQYLMV---PSLGKDLGFQVVREWLSDKGRTLSERQWNTVSKALDKCTLPLFVKLIYATVARWKSYSRPQETILFSSLQESINVLFHRTESQHGKLLVSHALSYISAARSGISDSEVEDLISLDDKVLDDIFQYHLPPVRRIPPLLWSRIR---SDLPGYLSERAAD-GVIVLNWYHQQFRQVAIERYFKNVNHLETCHSAMAEYFLGVWGGVPKPYQYTEMQKQRFGVTENEGLADRKVPKQP------NVFSSKDGNH------RYNTRKLNELPYHLLRSGRVDELLTLCLFDYEFLHAKVSSFPLQSLIADYEDAIQ-NVRDVEISRQLSLAVDALRLSASILSRNPSMLAFELLGRLLPLVATNKYVSKL--------LIKCDKEGPQHNSFVPAHHCFHAPGGPLKFSLEEHQFAVFGMQLT--SDRKLLVSTSTQII-VWDVSTGDIARVV 1035
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Fly
Match: CG10185 (gene:FBgn0038397 transcript:FBtr0083235) HSP 1 Score: 90.1225 bits (222), Expect = 2.007e-17 Identity = 101/467 (21.63%), Postives = 204/467 (43.68%), Query Frame = 3 Query: 1812 SNNPISCLISGPINGKTNLMCHLISAFQYNKLEH--SINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLR-IPEDIIGLKILLNQILLMIDF--KVMIFLDGIENIKEYKNDSNSMFNWLPLKMN-NCKVIFS--TEKSAPIYQNLLNFMKDSLDMLSIY-SIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKT---IGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTI--QKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMN---------------NNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTL 3125 S+ P+ G GKT+L+ +S H IN + R LG + ++ +T L S+C Q+ Y + IP+D++ L Q+L + I+LD ++ + + DSN + +W+P ++ +CK+I S E + P + + + +D+ + + L N+IK ++ + Q ++ + I +C + V + + R++T L N + +I+ F R+E Q G ++ L YI+ +G+S EL D+++ DD + + +L ++ +R +L ++L + G+ ++ W H + + A RY + A +H +++ YY+ + + K D +P PL +F ++ + + ++N R+ +LP H ++S+ +K L +FN+ W+ L Sbjct: 381 SDKPLVLFGDGGC-GKTSLLSKSVSLVATEWFAHVRPIN----VIRFLGTTPDSSALTATLISICQQISYNYMLPFENIPDDLVPLTAHFKQLLTYASPTQPLTIYLDSVDQLTGTQ-DSNKV-SWIPTRLPPHCKIIISCANEPANPTVSHEYHVLCKMIDVEENFIEVTALGEDLAMNVIKMWMKTACRDLNNYQWRLVANAISKCSLPIFVKLVFAEICRWRSYTRPQET-HLANTVMDSIMLLFERVEKQHGRILVFHALAYITASKSGLSESELEDLISLDDKVLDDVYQYHLPPTRRIPPLLWTRIR---NDLPNYLSE-READGVNVMNWYHRQFRDTAKERYFKNMNMAIYFHSMIADYYLGIWGGGVPKPFKFTEIQRHRFGLADKEGSADRKVPIQPL------VFSSKDGLSK-----RYNLRKFGELPFHFVRSRRFKDLFEHVLFNYDWLHAKL 824
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-212k18.6 (si:ch211-212k18.6 [Source:ZFIN;Acc:ZDB-GENE-130530-938]) HSP 1 Score: 239.58 bits (610), Expect = 7.762e-63 Identity = 249/1093 (22.78%), Postives = 490/1093 (44.83%), Query Frame = 3 Query: 2103 VMIFLDGIENIKEYKNDSNSMFNWLP-LKMNNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSS-----SVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVE---PGD-FSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQ--TGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIW--DNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIK---EVKILKRFNVFY-----DSYCLTVSSDKSLFTAFFYGIFWISTWSF-ETLDLVISRHLIID-TTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKH------------CSEMENIFDICEANELSRIFFASSK-SGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKKKSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRPN----------------PSVLSTSKSRLSXXXXXXXXXXXFISFGTANNTPVKQTSFLKASIHDLVIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCK 5222 + + LDG++N+ E + + +WL + + + ++ S A + +F++ + + S+ S+P L + + + + +S T+ Q +L + C + ++ + ++ W+S + ++PK N+L N+L LE ++G ++RRL IS +G++ ELL ++ D +++ + +L PG +S ++ + + L ++ T + +++W H+ + + RY +D + H + Y+ N + S +F+ PL ++++ GR + FN R++ LP+H + S L C+FN+ ++ L + +V E +K A + + ++ L ++L LS L+++P Q + Q+L R+ I+ +D+ +G+ R++ L +L +++ LP L+PS C+ P M +L+ VT L L + G L +W D + ++ G V + + ++L + L D + V + +V+ + V Y D +T + D L F+ G + ++ + L+ +L ++ ++ I+ S K L A + +AA+ + + G ++ L ++ AI V IS+ Y +L R P +S I +I+ F ES + R I GC D +S ++ G GSH + T++ IWN+ETE+HKH CS++ C L R++ S+ + + N+ ++ VT ++N +Y+ + + I+N+ R + G + ++DI L K+ ILSD + S V+Q + ++DL + K +FI PC ++++ +L ++ +GLS+ R H++ W+L +G I+ RI+ + PS T + N A +Q F + + ID L+S D ++ +YF+ L VFS+ ++ H+ TL +SLL L A++THNG +L+ +++ L+LW+ + Sbjct: 760 LTLLLDGLDNLSE---EHEADLSWLSDILLPHVFIVVS----ASTHSKCAHFLQSQVKV-SVLSLPALHHEEITSALASRLSSDSRQLTENQWTLLSQSCLSCPSPLYLNLAYAESKQWSSFTPENNLNIPKDPNQLFINVL---VSLEREYGSCLVRRLALLISLSRSGIAEEELLVLLGCDGHVKREMASLHHQTLPGSKYSPVPYAFVAGLLYSLRDYM-TEVESDDTWVLRWTHMEFCCVVLQRYAPTEDSVKAVHADFADYF-NGSAPNSQVFQ-----------PLAWIRKE--RGR-------RCYVFNLRKLHCLPYHYIHSGQIIPLLTECLFNYEFLLHKLWGLSIYHVQEDLKAAVIVDKDLLDVAVLAQVLSLSHSVLLNDPCQLASQLLGRLEQIICQDKPVTSGDPRRFSFLHDLLAQCRSSS-LPVLVPSYTCLLPPGGLMHTLLSGHMSAVTALAYG--GRHLVSCSSDGKLNLWRLDEQMRPVGALPRAHGCAV-----DWAADSLTLCLDDTVLVLQMGYCLQVREVHSGKVLYVEESLDVPVVTSACDGRLLVIFYDGCHMVKVFNLVSSCSLLFCVNLTLEFEPIHKDQSIVVSRQPAKDYVLFAYRNGGEAAVFNAKCGVVSSTLK-AQHPAGAIQAVEISSQYLLLFCR--YPYKRQSEIIHIELFSAESFQYLRSILGCSQDYISQVTVAGGGSHIVAFCPAPHHGTTEIIIWNIETEDHKHIARFPGLMTHGECSDLRFCVGFCVGERLLRMWNLGSRINDQTLTYNVHKVHIDGTAEIVTMQKN---------PRYVVCRSTRPGTVRIWNVARVRLKGRPVQVEHGLFSSSDIALIRDLKIYILSDLTTSNFTD--AAVYQTLLVYDLLKKSYIKKQTGLFIVPCPQQDYHLLEGEILLGLSETRDHLILWDLDSGYIKGRIKTSYKESLLLSMDTDSHIMPSKEKTGLVMPWDRRTETQNAKRIRQEREAKRKKDEQKRFEREKFNS--IDQYLLSGDEQVVVCSYFAHHLNVFSVISEEHLHTLEDRWSLLSLRTAAITHNGEHLVVSNYSEAQHAPFLTLWDTQ 1795
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Zebrafish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 75.0998 bits (183), Expect = 8.873e-13 Identity = 140/653 (21.44%), Postives = 269/653 (41.19%), Query Frame = 3 Query: 1809 LSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDII-----GLKILLNQILLMIDFK---VMIFLDGIENIKEYKNDSNSMFNWLP-LKMNNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSS--SVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFD-DTIQKFLTNLVEPGD----FSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYY--YMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAE----AEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSIITN------NWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWD-NSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVW 3662 +S+ P+ L+ GP GKT L+C L + N +V+ RLLG S ++D+ +LR VC Q+ + L+ P I GL + +L + + +++ LD +E + E + +W+P + N +++FST L ++ +I+ + L+ ++I Y+S T EQ++ ++ EQ + L A+ W+S + S L E + + LE G+ ++ L +I G+S EL D+++ D D + + + P F F +S LR +L + L + E+G+ L+ + H + RYL + KA + L Y+ + R +L S+ F+ N + Q ++F E N R+I +LP+HL + + L+ + + W+ ++ GV+ VI+ + L + E + ++ FL+ L F + +P +I +R+ L + Y S+I +W P L+P + +P + S + F V ++ L ++ G++ +W N+ L ++ + + ++++N L L + W Sbjct: 392 VSHGPL--LVHGPPGVGKTALLCKLAKEMRAV----VDNRGVVLLRLLGTSLLSSDVDSVLRGVCLQVC--GALGLQSPYSHIAYTHEGLVRFFHSMLEDVSKQGDTLLLILDSLEQLLE--TNKLHKLDWIPKIIPPNVQIVFSTSNECLDKCKSLVSAEE-----NIFKLELLTKDQGRDVIDAYMSAAERKLTAEQQDAILRYFEQSGNPLHLKLMLDTAKLWSSYTPMSSVHLDKSAEEVMTQFVESLEVNHGKKLVSHALSFILLSRYGLSEAELQDVLSLDNDVLAEIYKCWLPPSHTLMRFPRFHWSRLR---HDLSAHLTERW-EAGVLLLGFTHRQFAELVRRRYLSRDVKADMHTILAEYFSGQWSKGQLRPILLPSLSA-FL--NADRKVSPQPLWFSEELA---------NLRKIHELPYHLAHAGKWDELRQSVLGSLDWLCCKTLQCGVSCVIQDLTLCTDLTDCPEIQLLKETFLLLKPSLDFSDGRVDPSLLVTEIFARLQ----------------GLADHYPSMIGQLCSQCMDWFESYSDPLLVPKCSFFEAPGGPLKSTLRGFTKGVKAVVLCSKRKLLLAGSEDGLIIVWSLNNLQPLHTLSGHKAGVLSLKLTDKTNNCLSTGLDGTLRKW 997
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Zebrafish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-161213-1]) HSP 1 Score: 66.6254 bits (161), Expect = 3.358e-10 Identity = 119/541 (22.00%), Postives = 216/541 (39.93%), Query Frame = 3 Query: 1839 SGPINGKTNLMCHLIS-AFQYNKLEHSI-NDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLR-----IPEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSV--PKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFL---TNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYM--------------NNNYDRSVLFKSMDP-------------------DFILPNYPL----HIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFG-VNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIV 3299 GP GKT L+ + A+ + + E D +VI R +G + +TD+ +L+S+C Q+ +N R +P I ++ LL +L F ++I LD +E + + D WLP+ + +++ ST I Q L + D + + Q +K + + T Q+ + + +C FV R W S V L + + +I F +E++ G + R LGYI+ G++ +EL DI++ D+++ + +NL P S+ + + EL+ +L + L+ W + + A YL ++ H L++ Y++ NN++ + + +P D P P ++++ DIFF N R++ +L +HL +S L I NF W+ T+I+ G + + + LA E E FL L + NP S ++ R+ +V Sbjct: 418 GGPCTGKTLLLAEVAKQAYSWIQKEMGPETDPVVIVRFIGSTDFSTDLRTLLQSICEQI----AINYRCLIHFLPNKIQEMRELLVNLLGESSFHRPLVIILDALEQLSD--ADEARKLWWLPVHLPRTVRIVVSTLPNKHGILQKLRCLIHDEEAYVELM---QRDRKACSQTLKQQLLGVKRKVTSGQQIYVNEAMAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGSRFVFRALGYITMARAGLTELELEDILSLDNSVLGDIMVSSNLKSP---LRISYDFIARLKEELEGYL-VERQVHNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHNQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLEPDIFF-------------VNHRKMTELTYHLTRSGRTDDLMYGVIMNFSWLY-TMIKIGQFDKALSDIDLAYSYTQEK-ELKFLATTLRSIKLKVTKNPASLSAELQQRLLPVV 930
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000003639.1 (uncharacterized LOC101730828 [Source:NCBI gene;Acc:101730828]) HSP 1 Score: 245.358 bits (625), Expect = 5.994e-65 Identity = 302/1354 (22.30%), Postives = 561/1354 (41.43%), Query Frame = 3 Query: 1779 FLNETQHSISLSNNPISCLISGPINGKTNLMCHLIS-AFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFK-----VMIFLDGIENIKEYKNDSNSMFNWLPLKMNNCK---VIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSS------VPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLL-RCVCTELDSFLGTFYDESGIQ---LIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQT--GEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFETLDLVISRHLIIDTTV--------NNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKH------------CSEMENIFDICEANELSRIF-FASSKSGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKKKSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRP-----NPSVLSTSKSRLSXXXXXXXXXXXFISFGTANNTPVKQTSFLKASI----------------HDL-----VIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAVILNNTATLASY-FEKNQGLFLWKINNRIHHKLENSE-ANCCAEEFQDYRLEFLQEDSTLLAFNGSSFQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKENQ 5630 FL E Q I+ +N + + +GK++++ + + A Q+ D V+ R +G + ++ + +L S+C Q+ + + ED+ GL +N+ +++F +M+ +DGI+ + +++ +W+P + V STE + ++ L +++ IP L + + N+I+ ++ T QK++L C +V+SS + WTS SS P L +KL + +L RLE GE +++ + YIS GV++ ELLD+++ D + + E + + S+ + +L + +GT E +I W H + ++RYL K+ S H + YY+ + + P+ + PL ++ G +K FN R+IL + HHL+ S + L C+FN+ ++ + V + E +K A E + L + L LS L+ +P Q + Q+ R+ I D+ G + EL N L + SK+ G L +WD S + G+G + + + + + + ++WD+ K++ N D LT + D L AFF G + + DL S L+ + N ++S NS +++ L A + +A +++ R G I L +++ +++ V ++ Y+++ R P+ I +I+ F + + R + GC D + ++N GSH + + TN T++ +WNLETE+HKH C ++ C+ R + + + + +NI + + + +N+ +Y + +I ++N+++ K G +V++ DI+L KL IL+D+ + + +FQ + +D+ + + K ++I PC + E+ VL L +GLS+NR H V WN+ G I+ R+RP N + L E GT TP ++ + K + H L ID L+S+D ++ +Y++ LCVFSL H+ TL S+L L A+LT NG +L + D + ++LW+ + L NV + L + A + L +W+ R H + E N D +L+ ++ S + +G +WN+ D + V F PD I +L + I + + + +LK+ ++ Sbjct: 6 FLQELQDCITSANKQLVVVHGESGSGKSSIIAKIATLASQWIG-----RDIRVVTRFIGRTGESRNPRMLLYSLCFQIAEIYNITMDFSEDLKGL---INEFSTLLEFANKCRPLMVAVDGIDELSVHEDS----LSWIPRVLPRHVYFIVCASTESACSSFRTLQKLTMQQ----NVHQIPPLDSEEIRNMIEVWMERDNRRLTGRQKKVLFDACAACPLPLYVVSSYMESCLWTSYSSESDSYLQPNL-HKLYSAVL---GRLEKSHGEQVMKMVASYISLSKNGVTLEELLDLLSLDLGVMQ------EVKQYQNITVSVFPEALWIKLQNDIGTHLVEQRTDNTYVINWAHALFRVVCINRYLKSKELQLSVHSAFANYYLESKS------RHNHPEKVSLMMPL------MWTGTH------RKPVFNLRKILGISHHLIHSNQFPRLITECLFNYEYLLHKVWATSVVGLQEDIKAAINPERPAPDLNLLSEALQLSTKVLLRDPTQLASQLKGRLHQIEMLDKPVAPGHTEAITAVAEL------QNGLQAVTASKD--------------------------------------GTLKVWDLSTGKFIYTLHGVGKNIDSITVCMQNQIVALTEDHSFQIWDLTSRKVIYCDNDTLDIPILTSAMDGQLLLAFFDGSHLV-----KVFDLADSCRLVCQVAIPADEAPVHKNHSILVSRNSVKEYV-LFAYRSGKEAMVLNARKG-IVVAKLTAQDPVASVQGVAVTNEYFLVICR--YPSLKMHDIVHIELFSVNTFAYIRTVKGCSNDFICQIAVNRQGSHVVAFSQIPNTNTTEIVLWNLETEDHKHIVTFPSIPRGGICCDLRYCLAFCDGENYLRSWNLVNRINDQTLSMNINRLKRTDGIQEIITMKNFP--------RYAICRSMKPGLITVWNIVKSKCKGSAVRVERGLVESTDIVLVRDMKLFILTDRGMASFTETPRPIFQTLLTYDMLKKKYVRKQSGLYIIPCPKHEYRVLDGGLLLGLSENRDHFVIWNMDTGFIKERLRPKYKERNATDLLPEPDGCKEKLNKEELHQQKKQKGTVLLTPWERRNETKTAKRRRLDVEMKQEVEKMQHLLNEKNNAIDQYLLSEDEKVIVCSYYAHHLCVFSLETMTHLSTLEDTESMLFLHSAALTSNGSFLALSNYCDAEKISYVTLWDLQRGRVKKRLKNEPNVCCMALTDEADRIVFGIALENKLKVWEPFRRKHKIIPGYENLNLSV----DSKLQVIEGGSKAILLSG-EVSMWNLDD--GTLVSVFTPDSKICCLSLAADRTTILIGMSDTPSLINLKIASRDR 1247
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Xenopus
Match: ppp1r3c.1 (protein phosphatase 1, regulatory (inhibitor) subunit 3C, gene 1 [Source:Xenbase;Acc:XB-GENE-969181]) HSP 1 Score: 95.9005 bits (237), Expect = 6.622e-19 Identity = 139/643 (21.62%), Postives = 267/643 (41.52%), Query Frame = 3 Query: 1725 YLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIG-----LKILLNQILLMIDFK----VMIFLDGIENIKEYKNDSNSMFNWLP--LKMNNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIY-SIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKL----GNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGD-----FSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNN---NYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIE----IVKLAAEAEPEDIEYPFLIKLLILSFDNLI----DNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSIITNNWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWD 3542 Y++ER + +++P +++ H +S S GKT LMC AF+ K ++ L++ RLLG S Q++++ +L+S+C QL + L+ P I +Q+L + + +++F D ++ + ++ +WLP N C V+ + P +L +KDS+ Y + LS +I+ ++ T++Q+E+++ + +C + + A+ W+S + + +L K ++LY LE G+ ++ LGYI +G+S EL DI++ DD + + P F ++ LR +L+ +L G ++ H + A YL +K+ + H ++ Y+M R +L ++ N + Q ++F N+R++ +LP+HL+ + L+ + N WI ++ G+ VI+ VKL + E I LL + L +P+ ++L+R+ Y +DEL + WL PT IP+ + P + + V F VT + P L + ++ G++ +W+ Sbjct: 317 YIQER---HSQVYPPLII------HGVSGS-------------GKTALMC---KAFEMLKQTNN-GSSLMVLRLLGTSPQSSEIHDVLKSICYQLC--IALELQPPSSQITNIYNETVRFFHQLLTTVSERKVENLVLFFDSLDQLS--PSEGAHRLHWLPKECPANVCIVV----STLPEEGGILKTLKDSVTDPECYIEVKPLSAEQGSQMIEMLMASAGRRLTNDQQEIVLGSFRKCGQPLLLKLAFDEAKRWSSYTPITELMIATSTKEAVSLLYQC--LEQLHGKLLVSHALGYIVASRSGLSEAELKDILSLDDEVLADIYQYWAPPSNDLIRFPTLPWTRLR---NDLEGYL-VERQADGSTVLGLYHRQFIEVARDTYLTNTEKS-NRHGTLADYFMGKWSMGTKRPILLPLINKSL---NADRKVASQPLWFSDNMP---------NRRKMSELPYHLLNAGCIDELQGEILGNMDWISSKIVSCGIQSVIKDFEMSVKLISSRE---------IMLLRDTLSTLCLPSNTDPVIVFTEMLARMHFF---------QLSYRLIDELCQQC--TGWLHQYPHPTFIPTCGFFQPPGGPLQTTVTGFKKGVTVMELCPDHDLLVVGSEDGIMIVWN 886
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Xenopus
Match: hsp90ab1 (heat shock protein 90kDa alpha family class B member 1 [Source:Xenbase;Acc:XB-GENE-495311]) HSP 1 Score: 78.5666 bits (192), Expect = 1.280e-13 Identity = 111/476 (23.32%), Postives = 198/476 (41.60%), Query Frame = 3 Query: 1839 SGPINGKTNLMCHLIS-AFQYNKLEHSIN-DYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRI-PEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSV--PKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYM--------------------------------NNNYDRSVLFKSMDPD--FILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFG 3137 GP GKT L+ + A + + E + D +VI R LG + ++ + +L+S+C QL + L+ P+ I+ L L +L F ++I LDG+E + + +D+ ++ WLP+ + ++I ST I Q L + + + + IP+ + + ++K + + T Q+ + +C FV + R R W S V L + NI F LE++ G + R LGYI+ +TG+S VEL DI+ D+T+ + + ++P + ++ + +L +L + L+ W + A YL D H ++ Y++ N +Y+ F P+ + PL + DIFF N R++ +L HHL +S + + L NF W+ T+I+ G Sbjct: 415 GGPCTGKTLLLAEVAKKACSWLQEEMGPDSDPVVIVRFLGSTDMSSALNCLLQSICEQLAVNYRCLLQSRPKKILNLHELFLNLLNESSFHRPLVIILDGVEQLSD-SDDARKLW-WLPVHLPRTVRIIISTLPNKHGILQKLRCLIHNEDSYIEL--IPRDKKMCSQ-ILKHQLLRVKRKVTSGQQIYVNEAFSKCTLPMFVNLTFREVRNWRSHKDVDGSTLCVTVHRNIEQLFWSLENKCGPRFVSRALGYITMATTGLSEVELEDILALDNTVMSEVLSNMKPYIPLRIPYIMIAQLKEDLTGYL-VERQVRNVTLLVWANRHLQLVAQKFYLQNADDLQEMHSNMAEYFLGVWAGGIKKPFYNEPQYFENCIRKETRSILDENKHYNEQTSFDRQPPEQPWAFQCNPL---EPDIFF-------------VNHRKMTELLHHLTRSGMMEELMTGITMNFSWLY-TMIKIG 867
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 71.2478 bits (173), Expect = 1.531e-11 Identity = 104/475 (21.89%), Postives = 188/475 (39.58%), Query Frame = 3 Query: 1806 SLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDS-----------NSMFNWLPLKMN-NCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLG---TFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILP-NYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAA 3173 S ++ P+ L P GKT+LMC L A Q +L + +V+ RLLG S + D +LRS+ Q+ + L P ++ + F ++ N + + +WLPLK +I ST + NL +KD + + + LS + I+ ++ + + Q+++L +++ +C G + + AR W S + L E RLE+ G ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG G L+ H + RYL ++A + L ++ + + + + P P N + Q ++F + N R++ +LP HL+ + + LK + N WI I G+ +++ + A Sbjct: 332 SRTHTPL-VLFGPPGIGKTSLMCKL--AQQVPELLG--HKTVVVLRLLGTSKLSLDARSLLRSLSFQVCLAYGLPLP-PAQVLEAHSRVGHF-----FHTLLHTVSQRNFESLVLLLDSVDDLDSICHSPRVSWLPLKCPPRVHLILSTCSGQQVLHNLQQTLKDPS---TYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR-----DWTPPSKELLRFPPLLWVRLRRDLGHCLVRRPVDGCMLLAIAHRQLSQVIQVRYLSGPERAKRHGVLAEFF--SGAWSQGIKKLITLPLVGKPLNLDRKVAPQPLWF---------SSTVANLRKLTELPFHLLHAGRLEELKQEVLGNMSWISCRGISGGIEVLLDDFDMCA 776
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 71.2478 bits (173), Expect = 1.597e-11 Identity = 104/475 (21.89%), Postives = 188/475 (39.58%), Query Frame = 3 Query: 1806 SLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDS-----------NSMFNWLPLKMN-NCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLG---TFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILP-NYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAA 3173 S ++ P+ L P GKT+LMC L A Q +L + +V+ RLLG S + D +LRS+ Q+ + L P ++ + F ++ N + + +WLPLK +I ST + NL +KD + + + LS + I+ ++ + + Q+++L +++ +C G + + AR W S + L E RLE+ G ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG G L+ H + RYL ++A + L ++ + + + + P P N + Q ++F + N R++ +LP HL+ + + LK + N WI I G+ +++ + A Sbjct: 373 SRTHTPL-VLFGPPGIGKTSLMCKL--AQQVPELLG--HKTVVVLRLLGTSKLSLDARSLLRSLSFQVCLAYGLPLP-PAQVLEAHSRVGHF-----FHTLLHTVSQRNFESLVLLLDSVDDLDSICHSPRVSWLPLKCPPRVHLILSTCSGQQVLHNLQQTLKDPS---TYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR-----DWTPPSKELLRFPPLLWVRLRRDLGHCLVRRPVDGCMLLAIAHRQLSQVIQVRYLSGPERAKRHGVLAEFF--SGAWSQGIKKLITLPLVGKPLNLDRKVAPQPLWF---------SSTVANLRKLTELPFHLLHAGRLEELKQEVLGNMSWISCRGISGGIEVLLDDFDMCA 817
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Mouse
Match: Nwd1 (NACHT and WD repeat domain containing 1 [Source:MGI Symbol;Acc:MGI:2442268]) HSP 1 Score: 70.8626 bits (172), Expect = 1.741e-11 Identity = 104/475 (21.89%), Postives = 188/475 (39.58%), Query Frame = 3 Query: 1806 SLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDS-----------NSMFNWLPLKMN-NCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLG---TFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILP-NYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAA 3173 S ++ P+ L P GKT+LMC L A Q +L + +V+ RLLG S + D +LRS+ Q+ + L P ++ + F ++ N + + +WLPLK +I ST + NL +KD + + + LS + I+ ++ + + Q+++L +++ +C G + + AR W S + L E RLE+ G ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG G L+ H + RYL ++A + L ++ + + + + P P N + Q ++F + N R++ +LP HL+ + + LK + N WI I G+ +++ + A Sbjct: 332 SRTHTPL-VLFGPPGIGKTSLMCKL--AQQVPELLG--HKTVVVLRLLGTSKLSLDARSLLRSLSFQVCLAYGLPLP-PAQVLEAHSRVGHF-----FHTLLHTVSQRNFESLVLLLDSVDDLDSICHSPRVSWLPLKCPPRVHLILSTCSGQQVLHNLQQTLKDPS---TYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR-----DWTPPSKELLRFPPLLWVRLRRDLGHCLVRRPVDGCMLLAIAHRQLSQVIQVRYLSGPERAKRHGVLAEFF--SGAWSQGIKKLITLPLVGKPLNLDRKVAPQPLWF---------SSTVANLRKLTELPFHLLHAGRLEELKQEVLGNMSWISCRGISGGIEVLLDDFDMCA 776
BLAST of WD_REPEATS_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|Q149M9|NWD1_HUMAN (NACHT domain- and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=NWD1 PE=1 SV=3) HSP 1 Score: 77.0258 bits (188), Expect = 1.783e-12 Identity = 155/790 (19.62%), Postives = 297/790 (37.59%), Query Frame = 3 Query: 1320 EQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHK---SGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSM-----------FNWLPLKMNNC--KVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLGTFYDE---SGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLH----IVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSII------TNNWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILG 3578 EQ T+F +EI+ L I+E L + D + + Q + L HI + + L+ H+ S L + + H Y+ ++ +L ++ + EL + L + I L++ + Q + +++L + +H S + P+ L P GKT LMC L A Q +L + + + RLLG S ++D +L+S+C Q+ + L P ++ + Q F ++ N + ++M WLPL NC +V + L + LD + + + LS + +I+ ++ R + ++L +++ +C G + + AR W S + L E RLE G+ ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG + G L+ H RYL ++A + L ++ + L L PL+ + Q ++F + N R++ +LP+HL+ S + LK + + WI I G+ +++ L A ++ P + L+ LQ C+ + + R T + + + +++ +W P L+P ++ P + + + +T + L I T G++ +WD + + ++ G Sbjct: 182 EQGATVFLREIQDLHKHILEDCALRMVDRLADGCLDADAQNLLSSLKSHITDMHP--GVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRELDTAGQEL--AWLYQEIRHH----LWQSSEVIQTFCGRQELLAR--------LGQQLRHDDSKQHTPL-VLFGPPGIGKTALMCKL--AEQMPRLLG--HKTVTVLRLLGTSQMSSDARGLLKSICFQVCLAYGLPLP-PAQVLDAHTRVVQF-----FHTLLHTVSCRNFESLVLLLDAMDDLDSVRHARRVPWLPL---NCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYR-----DWTPPSKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLIT-----LPLVGKPLNLDRKVAPQPLWF---------SHTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCA----PHLDSPEV---------GLVREALQL-CRPAVELRGMERSLLYTELLARLHFFATSHPALVGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTG 908
BLAST of WD_REPEATS_REGION domain-containing protein vs. UniProt/SwissProt
Match: sp|A6H603|NWD1_MOUSE (NACHT domain- and WD repeat-containing protein 1 OS=Mus musculus OX=10090 GN=Nwd1 PE=2 SV=2) HSP 1 Score: 71.2478 bits (173), Expect = 1.071e-10 Identity = 104/475 (21.89%), Postives = 188/475 (39.58%), Query Frame = 3 Query: 1806 SLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDS-----------NSMFNWLPLKMN-NCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLR---CVCTELDSFLG---TFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILP-NYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAA 3173 S ++ P+ L P GKT+LMC L A Q +L + +V+ RLLG S + D +LRS+ Q+ + L P ++ + F ++ N + + +WLPLK +I ST + NL +KD + + + LS + I+ ++ + + Q+++L +++ +C G + + AR W S + L E RLE+ G ++ +LGYI G+S EL D+++ DD + + + D++ S LLR + L LG G L+ H + RYL ++A + L ++ + + + + P P N + Q ++F + N R++ +LP HL+ + + LK + N WI I G+ +++ + A Sbjct: 332 SRTHTPL-VLFGPPGIGKTSLMCKL--AQQVPELLG--HKTVVVLRLLGTSKLSLDARSLLRSLSFQVCLAYGLPLP-PAQVLEAHSRVGHF-----FHTLLHTVSQRNFESLVLLLDSVDDLDSICHSPRVSWLPLKCPPRVHLILSTCSGQQVLHNLQQTLKDPS---TYWEVKALSGSQGQEFIQLLLAAEKRMLSPGQRDVLWASLPECGHPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCIRLEETHGALLVAHVLGYIVSSRYGLSEAELKDVLSLDDEVLQAVYR-----DWTPPSKELLRFPPLLWVRLRRDLGHCLVRRPVDGCMLLAIAHRQLSQVIQVRYLSGPERAKRHGVLAEFF--SGAWSQGIKKLITLPLVGKPLNLDRKVAPQPLWF---------SSTVANLRKLTELPFHLLHAGRLEELKQEVLGNMSWISCRGISGGIEVLLDDFDMCA 776
BLAST of WD_REPEATS_REGION domain-containing protein vs. TrEMBL
Match: K1RYK2 (WD_REPEATS_REGION domain-containing protein OS=Crassostrea gigas OX=29159 GN=CGI_10026127 PE=4 SV=1) HSP 1 Score: 434.106 bits (1115), Expect = 4.665e-120 Identity = 429/1786 (24.02%), Postives = 793/1786 (44.40%), Query Frame = 3 Query: 567 IYVACSTFDMKNEISKLELNVWPHLRQLCLQYNRILVIHNLH-------NFSEELSSLGIQQYRKEIERSIEICSDQKSQHIKGLILFGDEYDEKDIPNYLLRDQIESIKSNMLPD----IEKIMNLQSNIQSLKQRQSQIKQQNFKRENTVENFRENSF--EDLNKSISKPTK---------ITEIDKINAEIINCTSEIETLNYVTNIKLIDQWYH-KANLTDNFYQLVSESEIIKDLKSPDFAKRKQARIIFKNIKTQLCAILSKYAANVLEQEQTL-------FEQEIK--LLTNIIMEKKCLLVSRTFTD---------------------KMMSEN----IQLQRNDLLKHINEENQI-RYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQI-LLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQL--LYETKVNLRIPEDIIGLKILLNQIL---LMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFST--EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVP--KLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGR--EFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVRED--RQTGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFETLD--LVISRHLIIDTTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKHCSEMENIFDICEANELSRIFFASSKSGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKK--KSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRP----------NPSVLSTSKSRLSXX------XXXXXXXXXFISFGTANNTPVKQTSFLKASIHDLVIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAVILNNTATLASYFEKNQGLFLWKINNRIH-HKLENSEANCCAEEFQDYRLEFLQEDSTLLAFNGSSFQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKENQAKI 5639 ++ C + + E S V+P LR C ++ L IH+LH L S+ + RK C S I L++ G++Y +P+ + D SI L + ++K+ + I+S Q + + QQ +E+ +++ +DLN + + T + ++ K +II E + + L+ QWY N Y+L + S +IK+ D R+ RI++ +L +L ++A ++ EQ+ EQE+ LL N + + ++V+R TD K +SE +Q + + + + N I +E+E K G + PAQ R H Y+D+++ K +L+ +K E S + E + + D L++E++ Q L + + + + E+L +T S S + ++ G GKT L C + Q H VI R +G + + ++ +LRSVC Q+ ++ +K +P + GL Q L D V+IF D ++ + + +++ + M +WLP ++ +N K+I +T E+ + L+ + D+ +IP + E+++K ++ T Q +++I +C ++ + +++W+S + + KL + F +LE + GEP++RR LGYI+ G++ +E+ DI++ D+ + + P S +R + D T G+ W H ++ AA RYL +DKAPSYH++++ Y+ + V P L V + F+ E H+ + +S +N R++ +LP+HL+ SQ + K + +F WI L + ++E + EP D E + ++ LS L +P Q + QI+ R+ I+ D R G+ +Y + L K + LP LIPS C+ P +F L+ +T + K F + + +WD + I +G + ++ + + ++ ++I+VW+++ + + R + + D + ++ + A F G + TW+ ++ H + +I+ S ++ I L A + N A + ++RNG+ + L + SA+ +GIS +YYI+ R +E IY ++ FD++ K R + GC+ D + IN +GSHAI +TN +D+++WN+ETE+HKH + + + A + N+ + + + + Y + N +Y NN + ++N+ R K KS + R ++ D++DI++ K+++L+DK + + + VFQ + I+DL + + K K+ FI PC E+V+L +++ +GLS+NRSH V WNL GQ++ RIRP V+S +K R + A + ++ LK I ID L+S D + ++F+ F+CVF + N H+ TL + S+L L +ASLTH G YL+ +++ + ++LW+C L NV+A+ ++ A+ + N+ + +W+ K++N + EF + F+ ++ T +W+I + GV + F PD I + + +I F L +I LKL+ + I Sbjct: 320 VHPPCVAENTEAERSTFIEKVYPELRTHCREHGFELQIHDLHWGLRDDSTDDHSLPSMCLNYLRK--------CQTSPSGGIV-LVVLGNKYGSYILPSVIPVDDFHSIHEQSLHEWKQKVDKMRKRIAEIESASQDRDKKIQQGLTEGQIMEDTKKDHLKTQDLNIKLEETTGKESLNMFRNLADMVKREQQIIKALKVKE--ETMPSPHLLSQWYKLDENCLPPVYRLQNISSVIKEYSRGDARTRESGRIMWNETVQKLRKLLDQFADLAIKDEQSRKNYFSSSLEQELDQCLLNNDDVTEDVIVVNRNITDLLSNLGDSTMADYADLSSTQDKTLSEPQTSYMQKLKTEFIPEKVDNNHILNHEIEWSKGG-VQPAQNRAHHLYLDRMS--------KQVLEVLKRE-------FSCHITEHVQQIDPTSKLYQEIS-QHVSLCQERGRHFQGRRELL----QTVKSYIRSKCRLPLILHGKAGCGKTALACKVALETQKWIKSH------VIIRTVGRTTASRNVRTLLRSVCLQMSHIFGSKTE-EVPMEFKGLVNDFAQRLGHASTADPLVLIF-DAVDQLSD-EHEGHKM-SWLPKELPHNVKMIITTNPEEQFESFPGLMKVYGSNKDI--TIAIPNMPQEDAESILKYWLQHDNRELTQHQFDVIIKAYNKCSLPLYLKLAFMESKSWSSFTEIENCKLSETITKLAALKFGKLESKHGEPLVRRALGYITASREGIASIEMEDILSLDEAVMDDVMANYRPSKRRCPSVLWIRLLEDLSDLLTPTLT--YGVITYVWAHSQFHQAADDRYLQNRDKAPSYHKVMAEYF------QGVWASKPKPCTGSEKGVLRYVSKQPFYYEPCENNHDGSDRS-YNVRKVNELPYHLLNSQQTAMYKSESLCHFEWIHAKLCGTSLRSLVEEYQTGLSVEPTDSELKMMSDVIQLSAKALSKDPRQLASQIVGRLATIIANDIPRAPGDPPRYPYIHALLKQAHEPS-LPALIPSIRCLTEPGGILFDLLSGHTDPITAVEVTSDGGKAFTASKDNTMKMWDLRTGKVMKTIHDVGTNITRIRVGYNVAFVITVEENVIQVWNLRYSERVLRVDKYPDPPVIGMAGEGKYLCALFDGNNTLRTWNLNKAGYPMISEAHTENHRVYKDNSALIAPFSFDERI-LHASRGANCALVNNVRNGK-QVLSLKCNDHSSAVISLGISRDYYIVACRQHYMQLHE--IYQLELFDLKRGKYLRSVRGCIHDKIKDLHINYIGSHAIAICASEETNTSDIAVWNIETEDHKHLARHAGASVLGACADFKYCLTAGRNDKTLNIWNLTGKINQSMPRLKKQSGVYQIMSMTKNPRYAVARQFNNGPVSVWNIARAKQLKSAVRIER--SLSDSSDIVVVRDTKVVVLTDKGIANAKDNARPVFQTVLIYDLLQKKFVKKIKKCFITPCPSHEYVMLKDEMLLGLSENRSHFVIWNLKNGQVEHRIRPMLKDLEKKIAETDVMSLAKDRCHTAKLTPWERRVESLSAKQRRRDAAVDIERQRVDELKKEISSSGIDRYLLSGDQKIAVASFFAHFMCVFDIENHTHMTTLESDTSMLSLLVASLTHTGNYLVQANYDEEQRTSYVTLWDCFEGVVKKRLKNESNVMALGISEDASKVIIGKGNKEIHIWEPQKTPSLRKIKNID----GLEFNELSKIFIVDNDTRAVVFAGDISVWDI-ERGV-VLAVFSPDTKITCCHVVNSGRVITFGLHDIPEIVILKLMSSDMPSI 2039
BLAST of WD_REPEATS_REGION domain-containing protein vs. TrEMBL
Match: V3ZQU4 (WD_REPEATS_REGION domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_236714 PE=4 SV=1) HSP 1 Score: 428.328 bits (1100), Expect = 4.292e-118 Identity = 436/1825 (23.89%), Postives = 804/1825 (44.05%), Query Frame = 3 Query: 510 SGSISNEVLNKY------YNSRTIHIYVACSTFDMKNEISKLEL--NVWPHLRQLCLQYNRILVIHNLHNFSEELSSLGIQQYRKEIERSIEICSDQKSQHIKGLILFGDEYDEKDIPNYLLRDQIESI--KSNMLPDIE------KIMNLQSNIQSLKQRQSQIKQQNFKRENTVENFRENSFEDLNKSISKPTKITEIDKINAEIINCTSEIETLNYVTNIKLIDQWY-HKANLTDNFYQLVSESEIIKDLKSPDFAKRKQARIIFKNIKTQLCAILSKYAANVLEQEQ-------TLFEQEIKL-LTNIIMEKKCLLVSRTFT-------------------------DKMMSENIQLQRNDLLK-HINEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELA--IQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVC---CQLLYETKVNLRIPEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFSTEKSA-----PIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTS--SSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGD--FSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMD--PDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVRED--RQTGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFETLDLVISRHLIIDTTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKHCSEMENIFDICEANELSRIFFASSKSG---KVFKLNIQSALQVAK-SKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKK--KSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRPNPSVLSTSKSRLSXXXXXXXXXXXFISFGTANNTPVKQTSFLKASIHDLVIDS--------------------------------VLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAVILNNTATLASYFEKNQGLFLWKINNRIHHKLENSEANCCAEEFQDYRLEFLQEDSTLLAFNGSSFQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKENQAKINQVK 5651 SG++ N VL Y S+ I IYV CS F + E+ + L V+P +R+ CL+ +LH +S + + + K ++ I C S I LIL G++Y +P + +D+ E I + D E K++ + SN Q+ + E EN+ + + KP I E I E + ++K ++QWY N Y+L + S K++ + D AKR QAR + ++ +L IL +YA VL+ + +LFE E++ L CLL+ RT DK E I+ R +L + E + +++E + G ++P R H +Y+D++ K++LD +K ++ +++ E +Q+ L+EE++ + Q + + R + E+L +T + S + ++ G GK+ L+ Y + + D VIYR + + +T++ +LRS+C C++ + + IP D G+ + + ++I LD ++ + + +D + WLP + ++ +I ST PI + ++ L L I +P+ +T+ + +++ + TDEQ E+L++ E+C T ++ + + +WTS + + KL ++ F RLE GE +++R LGYI+ +G++ +E+ D+++ DD + + +P F + L+ +LD +L ++ L W H+ + AA RYL Q+DKAPSYH+ ++ Y+ D+ + D D +L PL +F E + +N R++ +LP+HL+ SQ LLK + NF WI L + ++E + A + +D ++ L L LS + L+ P Q + Q++ R+ I+ +D G+ RKY L L N+ LP LIPS C+ P +F L+ +T + K ++ G + +WD + I +G++V ++ L ++ + + ++I++W I + + + D +SD A FYG I TW TL I + ++ I+++++ L A + N A +I R+ ++ L+ ++E S+I + I++ Y+++ R +E IY ++ FD + R + GC D +S +N GSHAI + N +D+++WNLETE+HKH + + I + R ++K +++ L+ Q K K + Q + +++Y +Y+ N+ I ++N+ + K ++ + R + + +D+++ +L+IL+D+ FS D K VFQ + I++LK R K +I P E+V+L E+ +G SDNR+H V W+L GQ+ +RIR + E G N K+ S L + DL +S +VS + ++ ++F+ LCVF + ++ H + E S++ L +A+LT++G +L+H +++ + ++LW+ + L +V ++ + + A + L +W + K + +F F+ E+ +W+I +V V V F PD I L +D+LI F L +++ LKL+ + Q +N+V+ Sbjct: 333 SGTMMNRVLQGYNYRRCHPESKMIQIYV-CSEF-VGTEVERTHLMEKVYPKIRRYCLEKGYDFRAIDLH-WSLQDDVIDDHRLPKLCQQVIGDCQSD-STAIDFLILCGEKYGTYVLPPEIPKDEFEEIYNTAKAFYDEEMQFIRDKLIAIDSN-------------QDVNLDAKTEASSENTNSETAATDDKPKIRGRKSVIRKETIRDLKARE--EALPDVKALEQWYILDENSVPPVYRLQNISSFYKEILNKDTAKRTQARQNYGSVMKKLLKILQEYAPKVLDDPEDRRKYFISLFEMELEHGLETDNSSPHCLLIQRTIRNVKNNLDDVTSAKYLDVTHPRSQQMDKSREERIEHLRETVLPMKVPESYRTEFKIEWYGGG-INPQTKREHSAYVDRMC--------KAVLDTLK------RDIGTALDDEGSMSNEQVKLYEEVSQHVAQCHHRSRNFHGRK---ELL----QTIKAYMRSPTKLPLVVHGKSGTGKSALLAKATKEI-YKWFKGT--DIRVIYRQIATTMASTNIRTLLRSICLQMCEIFDDNSCD--IPSDFKGIVNDFGYRMQQATKQKPLVIVLDALDMLSD-AHDGRKLI-WLPKDVPDHVHIIVSTLPDDKYLCYPILKKQYEGSENCL--LGISDMPENDAITI---LHHWLNSHNRALTDEQYEVLLNAFEKCPTPLYLKCAFNESLSWTSYTNPEMVKLSETVKKIATIKFGRLERDHGEALVKRALGYITASRSGITDLEMEDLLSMDDVVMDEVYAFHKPCSRRLPQFKWESLK---VDLDDYLLKRSADNTTTLC-WAHVDFCEAAQERYLNQRDKAPSYHKALAEYFRGIWVDKPKPYAGNDKGADRLLSPQPL-------YFEPENPNPSGSDRVYNLRKLNELPYHLLSSQQNSLLKSETLCNFEWILAKLCGTSLTALLEEYQFAHSVDEKDFDFKALSDALHLSSNALLCEPKQLASQLIGRLHGILSKDVPATAGDPRKYPFLHNLVAQA-ENSSLPALIPSHGCLTEPGGILFDLLSGHTEPITAVTLTNDGFKAVTSSKDGTMKLWDLRSGKVVKTIENVGHHVSRIRLAMNNTYAITSEDNVIKIWSITTGANIHTISEYVDPAVTITASDSCTLVACFYGSNMIRTWDLGTLTFT-GEERIPGSCIHKDRSILAADNSPTDKVLVAFRSANTALVIGARSKKVLQKLVCNEE-SSSIVALAITSEYFVVGCRQQYMKLHE--IYQLELFDAKKGYYIRSVRGCTHDQLSELHLNLHGSHAIAVCTSERNNTSDIALWNLETEDHKHLATHARLSTIGACCDF-RFCLTAAKDDNTLRIWNLSKQVNQHAPKLKKALGVGQIFPMKEYP---RYVVAKAVNHGPISVWNVAKAKCLQTAVRIER--GMTETSDVVIALNSQLVILTDRGFSNATDDSKPVFQTVLIYNLKTKRYERKLTSCYIVPAPSHEYVLLDENHLMGPSDNRTHFVVWSLQTGQVTYRIRTD----------FKEKVAKTKMAKGLALLGIGGNKK-KRASDLSMTPWDLRAESDADRERRHQKEKEQERNRLAELKKEKENSMEQFIVSGNQKKIVASFFAHHLCVFDIPSQTHTQVIENEHSMMFLHVAALTYDGDHLVHANYDEESKISYVTLWDLTTGEVKRRLKNESDVCSIGITDNANRVVIGKSPNELHIWDPMSPNSLKKIKGYSGL---KFSMGSKIFITEEGRRAIVLAGDISVWDIENVSVMAV--FTPDTKIMCCELAYHDSLITFGLYERSEVIILKLMCKGQP-VNKVE 2065
BLAST of WD_REPEATS_REGION domain-containing protein vs. TrEMBL
Match: A0A210Q3I7 (NACHT and WD repeat domain-containing protein 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT18745 PE=4 SV=1) HSP 1 Score: 420.624 bits (1080), Expect = 1.308e-115 Identity = 417/1789 (23.31%), Postives = 798/1789 (44.61%), Query Frame = 3 Query: 552 SRTIHIYVACSTFDMKNEISKLELNVWPHLRQLCLQYNRILVIHNLH-NFSEELSSLGIQQYRKEIERSIEICSDQKSQHIKGLILFGDEYDEKDIPNYL-------LRDQIESIKSNMLPDIEKIMNLQSNIQSLKQRQSQIKQQNFKRENTVENFRENSFEDLNKSISKPTKI----TEIDKINAEIINCTSEIETLNYVTNIKLIDQWYH-KANLTDNFYQLVSESEIIKDLKSPDFAKRKQARIIFKNIKTQLCAILSKYAANVLEQE-------QTLFEQEIK--LLTNIIMEKKCLLVSRTFTD-------------------------KMMSENIQ-LQRNDLLKHINEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLR-IPEDIIGLKILLNQILLMI--DFKVMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIY-SIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVP--KLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGD--FSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVRED--RQTGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPD-LIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSF--ETLDLVISRHLIIDTTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKHCSEMENI--------FDIC-EANELSRIFFASSKSGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKK--KSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRPNPSVLSTSKSRLSXXXXXXXXXXXFISFG-TANNTPVKQTSF-------------LKASIHDLVIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAV-ILNNTATLASYFEKNQGLFLWKINNRIHHKLENSEANCCAEEFQDYRLEFLQEDSTLLAFNGSS--------FQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKEN 5627 S + IY++ D E + E V LR+ C L +++LH ++ ++ Y +I C + + + L+L GD+Y +P+ + D ++ + + I++ ++ S+ ++ ++RQ Q + + +E S +S P K ++ K A+ + E E + +T+ +++ +WY N Y+L + S K+ + KR A+ F + +L + ++A V+ T+ EI+ +L + CL+V RT TD K S IQ L+ L + N + Y++E G + R+H YI+++ + L+K + I F+E++ D+ LF+E++ + +ER + + E+L + S S P ++ G GKT L+C H+++ V+ R++G++ +T++ +LR +C Q+ N+ +P D GL L + + ++I LD ++ + + + WLP ++ N +I ST Y+ N K + Y IP+L +++ ++ +T EQ E L+ ++C F+ + + A +WTS +++ K G+ ++ + F +LE + GEP++RR LGYI+ G++ E++DI++ DD + + ++ P F + LR +L ++ +S ++ ++W H + AA RYLL +DKA SYH+ ++ Y++ + F D + H+ Q ++F E + +N RR+ +LPHHL+ S +L K + NF W+ L + ++E ++ + +P DI+ L + LS L ++P Q + Q++ R+ ++ D G+ KY L Y + + L +LIPS +C+ P +F L+ +T + K + + +W+ + I G G V + I+ +N LV + +I VW+I+ + + + + D L + + A F GI + TW+ + + +V + ++ + +I+S+S + + L A + N A + + R+G++ L +++ SA++ +G++ +YYI+ R +E I+ ++ FD++ R + GC D +++ +N +GSH I +T+ +D++IWNLETE+HKH + + F C A + + + SGKV QS ++ K+ VT+ + N +Y+ N+ I ++N++R K ++ + R + + D+++ +++ILSD+ FS + VFQ + I+DL+E + K +I PC E+V+L + +GLSDNRSH V W+L G + RI+PN ++ S S N+ + A ++ KQ LK D I+ ++S++ + + +YF+ LCVF + N+ H+ + FS+L L A+LT +G +L+ +++ + +++W+C + L NV+A+ ILN+ + + KN+ L +W + AN + + Y DS + NG + +W++ + GV + F PD IN + ++ LI F L D+ L+L ++ Sbjct: 380 STVVPIYISSGFTDTLAEKTAFEETVSLDLREYCAARGYELELYDLHWGMTDTVTD--DHSYPGTCLTTINRCL-ESNPGVNILLLLGDKYGPYLLPSNIPVEEFNAFYDFVQDFRQREIDLIKEQIDEISSARAERERQRQDAESVLTDATDHSSEKEGSTRPEGSGVSSPAKTRRQNADLAKAEAQTLKNLKEQEAI--LTDPEILKEWYSLDENCIPPVYKLDNISAHYKEFA--NAKKRDAAKNSFTEVTKKLRGVFDEFAPMVITDPFARKKYFSTMIGLEIEHGILETDASDNHCLVVQRTITDISRNLNDSAATDFVDVSKENPHALDKTQSSIIQDLKLETLPTKVGVANILPYDVEWAAGGVIIGGH-RSHQHYIERMCKQVTETLKKQL--CIYFDERKRKV------------DDKTKLFDEVSQHVAFCQER-TKHFQGRKELLQLVK----SYLRSKCPSPLVLYGKAGCGKTALLCKTAKETHKWFRGHNMS---VLLRVIGITTSSTNVRSLLRDLCLQMCQVFGTNVEDVPTDYKGLMNDFTHRLSLATPENPIVIILDSLDRLSD--DHEGRKLTWLPKELPKNAYIIVSTNPDDK-YECFDNLRKSIPETSEAYIEIPELPEQDAITILEHWLHKNDKTFTGEQFECLVDAFKKCPMPLFLKIAFQDALSWTSLTALDQIKFGDNVKKQASFKFGKLETKHGEPLVRRALGYITASRNGLTNNEMVDILSLDDAVMDDIMSIYHPPRRRFPTILWVRLR---DDLQEYITVIKSQS-MRTLQWAHAQFKEAAEERYLLARDKAASYHKAMAEYFLGKWATKKKPFPGNDKGMLR-----HVSSQPLYFEPEDSVKDGSDRVYNLRRVNELPHHLLNSSQTELYKSQGLCNFEWVLAKLCGTSLRALVEEYQIGLQVDPTDIDLKTLSDTIQLSATALTNDPRQLASQMIGRLHGMIARDIPATAGDPPKYPYLHSFYDQAKSPSLL-SLIPSISCLSEPGGILFDLLSGHSEPITAMTLTSEGLKALTASADNTIKLWNIRTGRVMKTIDGTGTNV-RSIIPALNNALVATVEGSVIRVWNIRFSECVLTIDHYLDPPVLGTAGEGKYLVALFDGINIMRTWNLKRQIMPMVCEARIEDNSVYTDNSLLIASSSFDDKV-LHAFRGANMATVQNARSGKVIHTLKCNEKSSSAVS-LGVTRDYYIVACRQQYMTLHE--IHQLELFDLKKGHYLRSVRGCTQDHMTSLHLNYMGSHVIAICSSEKTSTSDIAIWNLETEDHKHLARHAGVSLMGACVDFKYCLTAAKGDKTLRIWNLSGKVN----QSMPKLKKTLGVTQ-----IIPMVNNPRYVVARQMNSGPISVWNVVRAKILQNAVRIER--GLSETADVVIVRNTRVVILSDRGFSSASDSSRPVFQTVLIYDLREKKYLKKLTGCYITPCPAHEYVMLDNENLLGLSDNRSHFVVWSLVNGHVVRRIKPNREIVQKSPSSTDRVLSIRNSTEVMTPWDRRAESSSAKQRRREDELDQERKRHEELKKE-KDNGIEQYIISENQNIAVASYFAHHLCVFDIVNEKHLHIIETPFSMLFLHSAALTPDGIFLVLPNYDEETKTSYVTMWDCTTGQIKKRLKNESNVMALAILNDGSRVIIGRGKNE-LHIW----------DPMSANGL-RKIKGYPGLQFNADSQIFVTNGGTQAVVIAGDISVWDL-ERGV-VLAVFTPDMKINCCKVAMDGQLITFGLHDIPDVVVLRLANKD 2094
BLAST of WD_REPEATS_REGION domain-containing protein vs. TrEMBL
Match: A0A1I8HP73 (WD_REPEATS_REGION domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 404.831 bits (1039), Expect = 9.270e-111 Identity = 481/1985 (24.23%), Postives = 854/1985 (43.02%), Query Frame = 3 Query: 120 HYDHWVKYDGKKTYSVLPEQGIKAHLQRLRFQRSVTQLKLKRKKEKTIFLKKRSTFL------------NKSASKNGNGIFDFTDLYNDSIETGSTWWRITPLPDIVKQTETDTEKETVDFVQQPFIEASSIKTRIEALKHFSGSISNEV---LNKYYNSRTIHIYVACSTFDMKNEISKLELNVWPHLRQLCLQYNRILVIHNLHNFSEELSSLGIQQYRKEIERSIEICSDQKSQ------HIKGLILFGDEYDEKDIPNYLLRDQIESIKSNMLPDIEKIMNLQSNIQ-SLKQRQSQIKQQNFKR----------------ENTVENFRENSFEDLNKSISKPTKITEIDKINAEIINCTSEIETLNYVTNIKLIDQWYHKANLTDNFYQL-VSESEIIKDLKS-----PDF-AKRKQARIIFKNIKTQLCAILSKYAANVL------EQEQTL--------FEQEIK--LLTNIIMEKKCLLVSRTFTD---------KMMSENIQLQRNDL-LKHINEENQIRYELEL-------HKS-------GKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMI-----DFKVMIFLDGIENI-KEYKNDSNSMFNWLPLKMNN-CKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTV---ENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVIS-SLRIARAWTSSSSVPKLGNK-LETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRC---VCTELDSFLGTFYDESGIQ---LIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMN---NNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDR--QTGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFETLDLVISRHLIIDTTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDS-VSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKHCSEMENIFDICEANELSRIFFASSKSGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKKKSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRPNPSVLSTSKSRLSXXXXXXXXXXXFISFGTANNTPVKQTSFL------------------------KASIHDL------VIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAVILNNTATLASYFEKNQGLFLWKINNRIHHKLENSEANCCAEEFQDYRLEFLQ--EDSTLLAFNGSSFQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKENQAKINQV 5648 HY HW + + +Q + +H++R R L + E RST L N + S G DF +S + + P ++ ++ +KE + FV F AS ++ E L S S++ +++T+ +YV S D E + + ++ PHLR + + + H G + + + ++IC + ++ + +IL GD++ + P + R + E I+ +K+ L+ Q L++ +++ K Q KR +T N R S S+ KP + + A+ + I NI+ I+ + N D +Y L S ++ L P+F A R Q + ++ QL A L+ + ++ E E T+ EQE++ +L + L+ RTF + + +I+ R+++ L+ + ++ +LEL H++ G ++P + R H +++ ++ I +LE I E+ +E S L+ TI E + L + + + +M +LN S++ I ++ GP GKT LM S + E S + R++GVS ++ ++ +L S+C +LL + K P+D G L+N+ + D ++I LD + + +EY+ +WLP + KVI ST + +L +K S ++ LTV E ++ +++ T Q E ++S C + + S + W S + K L+ ++ +Y +RLE FG+ +++R LGY++ G++ ELLDI++ DD + L +F F + RC L + LG F E + I W +N AA RYL QK+K P H+ ++ Y+ N + L + + + P + +Q+ F+ N R++ +LP HL +SQ ++ LK C+ NF +I ++ V +V+++ + AEP D + + L LS L +P Q + Q+L R+TD+++ DR + +KY + L+ NN +PTL+PSK+CM +P + L+ +T + + T F ++ + +WD + + + S I G G+ V M L + L+ + ++V+ +K +L V D + V+ D + F GI + TW+ E L V + L +T ++ ++ S CN + L ++ N A ++ R+G+ + + L +K S +T V S YYI+ + + + +++++ FD K+ RRI GC DS V + + H I+ N NMTD+ WNLETEEHKH + I I + R+ S + N+Q +Q A KT + + N++Y +NSVI +++ K SG +I ND++L + +I+L+ FSP VP+ K V+Q + IFD+++ + V I PC +E+ V+ + + +++ ++ + ++L +G+I RI+P S +K R S + + F N+ KQT F+ K +L I L+SKD ST++ ++F+ +CVF+L+N L +LL L ASL+ NG YL H +N+ + L LW+C++ ++ V AV +N+ A++ Y ++G + R K+ ++ + C Q F+Q D S +WN+ + + PDQ ++S L LND LI F K SND LK+L N + +V Sbjct: 48 HYGHWKLFRQSRAMGTERQQLVISHMKRGLRHR----LDRRPADEHESLESDRSTGLFQRYSQYGVQRSNSTLSTAGVIPVDFLHPETESTPPAAGPATLAADPQQDEKVKSLLDKE-LTFVNT-FAVASELE---EVLSRQSSSMTALPPIGARTRDDAKTLLLYVTSSLGDFDAERAAMAEHLVPHLRDTARSFGLDFRLIDPH--------FGCRFHACDNHEDMKICQEALAKTKLYKDRLNHVILLGDKFGKPSSPPTIDRAEFELIRGEYNSAYQKLQQLRVERQKELEEMETERKVQEEKRNRAGADDDDTDDDFEDASTRRNNRRTSVNRRRSSV-KPKPKASLTSV-AKTVGRAMLIRKSQLEDNIRSIEPYLPSENFLDTWYYLDSSRVPVVYRLAQVSSVLPEFSAYRMQVQDQWQRTDQQLLATLTFCSRRLVKNDVMPESESTILALNKTSVLEQELRQTVLRSRGSHSDTLMFVRTFDNLKDQVGQPLAALYTDIEPGRDEVDLEAAHAFVTVKRDLELMVPEDIIHRAQISWIPEGGVNPERSRIHENHVKKICAQIIRVLEPQIRQIGLDLERHQTEQQS--LMHTIQENENYCLQHAAECYGR---------KTMLAKMKAYLN--------SDSMIPMVVHGPSGSGKTTLMAKCFSKLKDWLPESST----CVVRVVGVSSRSGNVRYLLGSICRELLLKWKEQGDPPQDFAG---LVNEFTARLQQASRDRPLVILLDSLGQLTEEYQ---GRRCHWLPKVLPKYVKVIASTVGDERV--GVLGQLKSMYSDASPDHFMEMEQLTVEEAEKILSSWLAKEGKTLTTPQLEHVLSAF-NCVPLPLQLRLSFHESLNWPPSFLPREFAAKTLKQSVTFYLSRLESGFGDLLVKRALGYLTAAKNGLTEAELLDILSLDDHVMDVL-------NFQ-FHLPVRRCPPIAWLRLRNALGEFLTEKSVDNCVTIVWAFNMFNEAAAERYLNQKEK-PVLHKALAEYFDGMWAGNKRKPHLGNEAGSNRFVSSQPYYFERQE---PPGFV--------CNDRKLAELPWHLRESQQFESLKQKCLCNFDFILAKMLASSVRHVLDLYESVLSAEPRDKDLRLISNSLYLSRAELELDPKQLASQLLGRITDVLKADRPKAPADPKKYPFVHALFYRARRNN-VPTLVPSKSCMTTPSEIVLDLLQGHRLPITAVCISEDGTTGFTSSQEDTIKVWDLTNSRVVSTIEGSGSQVLSMTLGRQESVLITSELTCVKVYAVKIGCLLFTIPVQDDPCSVVVNGDTNNLVCFHQGICVMRTWNLERLTKVCDKTL-TETGLHQDRTVVVSTRCNADLVLYGLRGSNFARVVHCRSGQ-DVLKLSCLDKASLVTAVQTSREYYIVACQA-TDLHTRVHMFFLELFDTGKGKSVRRIKGCSSDSVVDELMLTNIQQHVISLNPMRDKNMTDIVAWNLETEEHKHFTRHPGISSIGAVYDFRRVITGSLAENALRMWNVQQNMQSAPQKTESLVNLADIVIDAGNNRYALTKLSDNSVIHAWSLSANKFSGKVVKSAKSIAGPNDMVLMDRHFVIVLARPGFSPKVPNAKFVYQTLTIFDIQKQKFTVNLNNVLIVPCAYEEYHVIHGNQLLCINEFHTNFLVYSLESGEIIRRIKPEFS-FDPNKKRPSALLEGSVLQRENEMFEEFINS-RKQTVFMTPWERRNESKSAKTRRYRSEWEEKKQRADELEQEKGNGIADFLISKDQSTVVSSFFAHHICVFNLSNGTQQSVLEHPNALLHLFTASLSPNGRYLAHTIYNEQQEMSQLCLWDCRT-GKVKKSFNEGGVGAVAVNSDASILVY-GTDRGELQVRDCRRSPAKVRVAKTSACVNFQQSSHRNFIQLFRDDKWALIYARSLSVWNM--QSLEMLSILTPDQPLHSIRLALNDQLIVFSSKDSNDPIILKMLSANSKRPQRV 1951
BLAST of WD_REPEATS_REGION domain-containing protein vs. TrEMBL
Match: R7TMM5 (WD_REPEATS_REGION domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_208371 PE=4 SV=1) HSP 1 Score: 402.905 bits (1034), Expect = 4.427e-110 Identity = 344/1456 (23.63%), Postives = 667/1456 (45.81%), Query Frame = 3 Query: 1413 DKMMSENIQ-LQRNDLLKHINEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKER--KVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQL--LYETKVNLRIPEDIIGLKILLNQI--LLMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKMNN-CKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSS--SSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRK--YLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFET-------LDLVISRHLIIDTTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKHCSEMENIFDICEANELSRIFFASSK--SGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKKKSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRPN-------PSVLSTSKSRLSXXXXXXXXXXXFISFGTANNTPVKQTSFLKASIHDL------VIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAVILNNTATLASYFEKNQGLFLWKINNRIHHKLENSEANCCAEEFQDYR---------LEFLQEDSTLLAFNGSSFQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKENQAKINQV 5648 DK + +++ L+ +L K ++ N RY + +G + P+ +R H Y D+ + IL ++ E+K ++ L E+ + + R K+L + L + + I L N LI G G T++M +F S + R++GV+ ++ + +LRS+C Q+ +++ N R+P D+ GL + + D +V+IF+D + + + WLP + ++ S++ + + F + D + + + L N+ ++ ++ + T Q+E++++ C+T F+ + + +W+SS S K+GN ++ RLE ++GE RR LGYI+ G+ I+EL D+++ D++ + G LLR + + D G + W+H AV RY+ +DKAPSYH+ ++ Y++N +D+ F + +V Q +F + + + +N R++ +LP+HL++SQ + +LK C+ NF ++ + G+ V++ ++LA EP D++ L L LS L +P Q + QI+ R+ I+R D+ Y L Y + N+ P+L+PS C+ P S ++ L+ +T ++ + K+F T+ L +W+ + I+G+G +V + L ++ + + I VWD+++ + + + + D + + S+ FF+G + +W ++ LD + ++ + + + N L A K N A + ++++GE+ + + +K S+I + S +YI C+ F N + + I+ FD + + R ++GC LD S +N VGSH I + + +D++ WN+ETEEHKH ++ + +L I AS S +++ L+ + + K + + TL N +Y+ + NN + ++N+ +K SG + +V+ +DI+L +KL+IL++K S + VF+ I ++D+ E + + +++P E+V+L ++ +GLS+NR+H+V W+L+ G I RI+PN P + + S K+ KA I + I+ ++SKD ST++ +Y++ LCVF + ++ H TL + S+L L +++LT+NG +L+H ++D + ++LW+C S L NV A+ +++ A + +++Q L +W E E N + + Y + + S + F G +W++ + GV + F PD I + ++ ++ LI F LK +N + +LK++ I ++ Sbjct: 605 DKGLQKSLANLRMAELTKKLSFRNIRRYTVAWAPTG-IDPSTIRAHGVYCDRFVKDFYEILVANLSTFFAGEQKSKPR-----------NESKLQLINEIKYHIAFCQARASKMLGRKPI------LQKIRDHI-LKNCKFPLLIHGQAGCGLTSIMAKAAVSFAPRDPSCS-----TLIRMIGVTGESFNARTLLRSLCLQMSHIFDQNPN-RVPHDMKGLSNIFEFLCGFAHEDQEVVIFIDSLHKLSD--EHEGKKLAWLPRNLPEYVHMVLSSQSAGQGSDCVKAFTQAYGDEM-LLEVQALENIEASVMLAHWLEDAKRRLTMPQREVIMAAFAACQTPVFLRVLVNESFSWSSSYDPSGLKIGNAVKNVATVMMGRLEKEYGEAFTRRTLGYITASRKGLMIMELEDLISLDESAMDEIVAQNRIGIRRIPPVLLLRLYYSIMPHIQEVNAD--GHVTLMWKHSQVAEVAVERYMNARDKAPSYHKAMAEYFLNTWHDKLKPFSGNEK-----GSHRFVVAQPLFRTKTNPAGEVLGTTYNLRKLYELPYHLIKSQQHDVLKKSCLCNFEFVLAKISASGIQAVVDDLQLALSVEPADMDLKLLSDTLHLSSTALSKDPRQLASQIVGRLDTIIRMDKPVAPSDPVVYPALKSFYAQALRNS-TPSLLPSAACLSQPGSILYDLLSGHTDGITAVVVSSNGQKVFTTSLDDTLKVWELRSGRVIKTIVGVGKHVLHIRLGLKATLVITSEINAIRVWDVEKGECVYQIDS-DDPATVGTACGGSILVTFFHGCSRMKSWQLDSDFKELVDLDFELENPEEPAQGIHKDNSTLLAGNSNGDKVLHAFKDANYAMVRNVKSGEM--IYKLNCKKASSIQALASSREHYI-CAVRFR-FNISTETHQIEVFDNTNGQPYRVLAGCTLDHFSEIFVNNVGSHIIAISYSVSNQSSDIAGWNIETEEHKHLAKHAKVSKFGSCVDLRYILTASEAEPSLRIWNLSAKINQPCPREKPINGVE--TLVPMVDNPRYLVAKSFNNDPLTVWNITKKGFSGSAVYTERGLVEMSDIVLVRNNKLVILAEKGPSNVSKQGH-VFKTIHVYDMVEKKYIQRLSGCYVFPSPMHEYVILHDEQLMGLSENRTHLVIWSLTTGHITHRIKPNFKADYVLPDKEPNNFRTRGTTAEMTPWQRRSESASARKRRHQKEIEDEKAKIEAMKKEKENSIEQYIISKDYSTIVTSYYAHHLCVFDIQSQTHTQTLESQTSMLFLHVSALTNNGSHLVHTNYDDESKASYVTLWDCGSGLIRKRLRNEKNVQAIAISDNAQRVVFGKRSQELRIW----------EPFEPNSL-RKIKGYPSLNFGIGSVIHIVDNGSKAIVFAG-DISLWDLAN-GV-VLAVFTPDMRIQTLSVVMDGRLIVFGLKDTNKLVTLKMVYPGAPPIEKL 2002
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-212k18.6 (si:ch211-212k18.6 [Source:ZFIN;Acc:ZDB-GENE-130530-938]) HSP 1 Score: 223.016 bits (567), Expect = 7.356e-58 Identity = 387/1781 (21.73%), Postives = 724/1781 (40.65%), Query Frame = 3 Query: 555 RTIHIYVACSTFDMKNEISKLELNVWPHLRQLCLQYNRILVIHNLHNFSEELSSLGIQQYRKEIERSIEICSDQKSQHIKGLILF---GDEYDEKDIPNYLLRDQIESIKSNMLPDIEKIMNLQSNIQSLKQRQSQIKQQNFKRENTVENFRENSF--EDLNKSISKPTKITEIDKINAEIINCTSEIET--LNYVTNIKLIDQWYH-KANLTDNFYQLVSESEIIKDLKSPDFAKRKQARIIFKNIKTQLCAILSKYAANVLEQEQTL-------FEQEIKLLTNIIMEKKCLLVSRTFTD---KMMSENIQLQRNDLLKHINEENQIRYELELHKSGK--------------------------LSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENI-KEYKNDSNSMFNWLPLKMNNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLG---TFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSK-FNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPED-IEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTG-EVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSP-------ISSMFSLVGFFFGN---VTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFETLDLVISRHLIIDTTVNNKGE--------IISSNSCNK--FIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYIL-CSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKH-----------CSEMENIFDICEANELSRIF-FASSKSGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKKKSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRP--NPSVLSTSKSRLSXXXXXXXXXXXFI---SFGTANNTPVKQTSF------------LKASIHDLVIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQIS-HLTVRHNVLAVILNNTATLASYFEKNQGLFLWKINNRIHHKLENSEANCCAEEFQDYRLEFLQEDSTLLAFNGSS-------FQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDN 5564 R IY+ C + E S L V+P L C Q + +L + I + E IE+ +K Q +G F G +++ + +P + + E+I + D +K QS +R+S++ K ++++ + SF E + T + + N++ ++ S+ E + ++ L+ WY N Y+L+ + + D S D +RK A+ +++ + +L + + T +E E L + E+ R TD + SE Q Q DL K E NQ LH+S + LSP R+H Y +++ + Q I+ + L+ +K ++ E + L EE+ Q +L+ K F + L + IS S+ L+ P +GK+ LM ++ L I+ V+ +G++ + ++ +L+ +C Q+ + I E I L LL +L+ D + + LDG++ + +E++ D + ++ P + ++ S KS K SL L S +++ L D W +L+ C ++ ++ ++ +W+S + + L +L++ FA LE + GE ++RR + GV+ ELL ++ D+ + + + L + S+ + L +G T + G ++ W H + A RYL +D + H + YY + D S+ Q + + RE E K+S FN R++ LP+HL++S L CIFN+ ++ L +G+++ L A P+D ++ L++ L LS L+ +P Q + Q+L R+ I +D+ + +Y L L ++ LP L+PS +C+ P ++ + + FG V+C + + KL+ D L ++ S G + L + LV+ ++V ++ K+ + D +T + + L F+ G S + DL S L+ V + E ++S NS F A + +AA+ +G + V+ ++E+ ++I V +S+ Y +L C P ++ I +I+ + S + R I GC D +S +IN G+H I +T T++ WNLETE+HKH C ++ C R++ S + + NI + + + + KY Y+ + ++N+ R G ++ ++D++L KL IL+D+ + V+Q + ++DL + +FI PC ++++ +L +L +GLS+N H++ W+L +G I+ RI+ S+L++S + ++ E + + T ++T K+ L+ H+ ID L+S D +I +YF+ L VFS+ ++ H+ TL +SLL L A+LTH+G +L +++ L+LW+ + Q+ L + V + N A+ ++ L +W+ R H + YR L S L G + +W++ D G + + F PD I ++ ++N Sbjct: 174 RRFMIYL-CGGYLTVAERSALMERVYPQLYLYCKQRGYDFRMVDLRRGVTD----PISDHNDSAELHIELL--KKCQETEGPSFFMFTGQKHEVQSLPTTISQGDFEAILRTVTRDRKK--------QS--KRESEVDDVTVKSQSSLGISNDGSFTLEHRPGEEEEHTGSSALMSENSKSLSSFSDGEKTEADNDQDLGLLQTWYQLDENTVPPVYRLLPVTHL-PDFLSRDGQRRKAAKKAWRSTCLHIWGVLQCNGPEAIGETATSHLLRTLDWEMEQGLGAKLPAEEYSHCYKRIITDLLYNLRSEYAQ-QFIDLHKGRPEINQT-----LHRSQQSFIHNIHSKLRHTNIYETNVSWGRKGLSPKHNRSHQFYTERLCSHFQRIV-TTALNQVKPVKRSFDV--------RRREASRTRLHEEM---QLHLRHGKSAQSFEFRQNFLLEVKDSLEISASSQNALLLLGEPGSGKSTLMAKVVQL-----LPTWISKVKVLVCFVGLTSDSRNVRLLLQMICTQMADIYCKHTEISELIRELHSLL--MLVSEDRPLALVLDGLDELSEEHEADLSWLYTPPP---PHVYILLSASKS---------HAKVSLLSLPPLSSEEITAGLRSRLASDARRLQTAQWN-----LLLQRCLSCPNPLYLSTAYSLSLSWSSFTPPEQTTLPGQLQSLFQGIFASLERKHGEHLLRRAASLLCLSRCGVTEEELLRLLGRDERVAQEIAKLHNQTQTTSGYDSVPLVLWARLRHDIGYHLTQVESDGTWVLHWTHSEFGQVATQRYLKTEDTTRAVHADFAEYYGADGPDSSIF-------------------QPLAWSRE---EGGKRSYVFNLRKLHGLPYHLIRSGQILPLFSQCIFNYEFLLHKL--WGLSFCHIEEDLKAAIIPDDLVDKDMLVQALCLSRSVLLKDPCQLASQLLGRLLHITTQDKPVAPDPLRYTYLHTLMAQ-CQHSTLPVLVPSYSCLMPPGGLTHTLLTHLSPVTALAFGQDHAVSCSVDG--TLKLWKLDDTVAL-----ARTLPRSEGFTSGWAADSLTLCLKDSVLVLRKGHRLQVREVDSGKVFYTESESLDVPVVTSTGEGRLLVVFYDG-------SHKVFDLAASCSLLRCVNVTLESEPIHKDNSILLSHNSIKDHVFFAYSG----GEAAVFSANSGTVLSVVK-AQEQAASIQAVEMSSQYLLLFC----YPYKRDTEIIHIELYCPASFQYLRSILGCSQDYISQVTINRGGTHVIAFCPSNRTVSTEIITWNLETEDHKHMARFPGLLTAICPDLRFCLGFCSGERYLRLWNLISRINDQTLTYNIHRVQRDGTQEII------PMDKYP----YVVCRGIRTGTVRVWNVSRAHFRGRPVRVEHSLFSSSDVVLAQDLKLYILTDRGTATFTDTPTPVYQTLLVYDLLTRSYVKRQSGLFIVPCPQQDYRLLRGELLLGLSEN-DHLIVWDLDSGYIKGRIKTYHKESLLTSSPLKDQQSQTVLTGERKLMMPWDWRTESHTAKKRRQQFEERREKEEQRNLEREKHN-SIDQYLLSGDEKVVICSYFAHHLNVFSVDSQEHLHTLEDRWSLLGLCTAALTHSGGHLAISNYSEVQRSPYLTLWDTQHGRQVQKRLKNEPGICCVAITNDASRIAFGIMKSNLKVWEPFRRKHKTISG------------YRGLKLDVSSQLYVTEGGTKAILLAELSVWDL-DAG-TVLSVFTPDSRIQCVSVLGDEN 1820
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Cavefish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 78.5666 bits (192), Expect = 5.755e-14 Identity = 143/666 (21.47%), Postives = 280/666 (42.04%), Query Frame = 3 Query: 1800 SISLSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIP-------EDIIG--LKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKMN-NCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVEN---LIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVP--KLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFD-DTIQKFLTNLVEPGD----FSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMN---NNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEA----EPEDIEYPFLIKLLILSF-DNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNL-DELYKSIITNNWL-----PTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWD-NSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKIL 3686 S+++ + P+ ++SGP GKT ++C L + ++ V RLLG S ++D+ +L+SVC Q+ NL P D++ + +L+++ D +++ LD ++++ + N + + WLP ++ N ++ ST +P ++L D Q+ LT+E + K Y+ T EQ + ++ + ++ + + L +A+ WTS +++ +LG+ ++ I + LE + G+ +R LGYI+ G+S EL DI++ D D + + N + P F ++L R +L L + E+GI + + + RYL + + H ++S Y++ + +L + P N + Q ++F N R++ +LP HL+ + ++ L+ + + + W+ + GV VI+ + E I FL+ + F D ID+ L +I +R + Y +L LY +W P L+P + M +P ++ + + F VT + + L ++ G+L +WD L + + G ++N+ L I+ W + K L Sbjct: 4 SLNMQHGPL--VVSGPPGSGKTAVLCRLAQEMRAVLGPQAV----VTLRLLGTSPLSSDVDSVLKSVCVQVC--GAFNLAPPCTQTANSHDMLVRFFQSMLHKVSEQGD-TLLLILDSLDHLP-HANGGHKL-RWLPKEIPPNIHLVVSTLADWSPCLESLKALNNDDKYFF------QVEPLTLEEGQLITKAYMDKAGRRLTSEQVDAVLQSFQKTGSPLHLKLLLDMAKQWTSYTTLSDIRLGSSVQEVISLFLDSLEGKHGKLFVRHALGYITLSRFGLSEAELQDILSLDNDVLAEVYQNRLPPNHTLLRFPPLLWALFR---QDLGDHLVERW-ENGIAVCGFSLRQFIEIVKERYLSVELRV-KMHTVLSEYFLGQWSQGQQKPIL---LHPLMTQLNADRKVPAQPLWFAEGIP---------NFRKLHELPFHLLHAGKWEELRQLLLGSLEWLYCKTLSCGVASVIQDFTFCTDVMDCPEIRLIRECFLLLKPTIDFIDGNIDSSL-LCTEITARFQAL---------AHAYPDLIGCLYSQ--CQDWFASCADPVLVPRCSFMEAPGGALKNTLNGFTKGVTAVDVCCEKSILTAGSEDGLLIVWDLKHLEVLHTFVAHTGVVECVKLINKGDQCLSAGRDGCIKKWSVCSGKQL 623
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Cavefish
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 73.9442 bits (180), Expect = 1.694e-12 Identity = 112/485 (23.09%), Postives = 215/485 (44.33%), Query Frame = 3 Query: 1800 SISLSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIP-------EDIIG--LKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKMN-NCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVEN---LIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVP--KLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFD-DTIQKFLTNLVEPGD----FSGFSFSLLRCVCTELDSFLGTFYDESG-----IQLIKWRHLSYN-----NAAVSRYLLQKDKAPSYHQLVSYYYMNN-NYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIE 3155 S+++ + P+ ++SGP GKT ++C L + ++ V RLLG S ++D+ +L+SVC Q+ NL P D++ + +L+++ D +++ LD ++++ + N + + WLP ++ N ++ ST +P ++L D Q+ LT+E + K Y+ T EQ + ++ + ++ + + L +A+ WTS +++ +LG+ ++ I + LE + G+ +R LGYI+ G+S EL DI++ D D + + N + P F ++L R +L L + E+G I+++K R+LS + +S Y L + ++ + M N DR V P PL +F N R++ +LP HL+ + ++ L+ + + N W+ + GV VI+ Sbjct: 334 SLNMQHGPL--VVSGPPGSGKTAVLCRLAQEMRAVLGPQAV----VTLRLLGTSPLSSDVDSVLKSVCVQVC--GAFNLAPPCTQTANSHDMLVRFFQSMLHKVSEQGD-TLLLILDSLDHLP-HANGGHKL-RWLPKEIPPNIHLVVSTLADWSPCLESLKALNNDDKYFF------QVEPLTLEEGQLITKAYMDKAGRRLTSEQVDAVLQSFQKTGSPLHLKLLLDMAKQWTSYTTLSDIRLGSSVQEVISLFLDSLEGKHGKLFVRHALGYITLSRFGLSEAELQDILSLDNDVLAEVYQNRLPPNHTLLRFPPLLWALFR---QDLGDHLVERW-ENGIAVQFIEIVKERYLSVELRVKMHTVLSEYFLGQWSQGQQKPILLHPLMTQLNADRKV-----------PAQPL-------WFAEGIP---------NFRKLHELPFHLLHAGKWEELRQLLLGNLEWLYCKTLSCGVASVIQ 770
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682]) HSP 1 Score: 71.2478 bits (173), Expect = 1.305e-11 Identity = 112/487 (23.00%), Postives = 205/487 (42.09%), Query Frame = 3 Query: 1839 SGPINGKTNLMCHLISAFQYNKLEHSIN---DYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLR-----IPEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSV--PKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFL---TNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYM--------------NNNYDRSVLFKSMDP-------------------DFILPNYP----LHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFG 3137 GP GKT L+ ++ Y+ L+ + D +VI R +G S +TD+ +L+S+C Q+ +N R +P I ++ LL +L F+ ++I LD +E + + +D+ ++ WLP+ + +++ ST I Q L + D D + + + + L + +S R T Q+ + + +C FV R W S V L + + +I F +E++ G + R LGY++ G++ VEL DI++ D+++ + +NL P S+ L+ + EL+ +L + L+ W + + A YL ++ H L++ Y++ NN++ + + +P D P P +++ QDIFF N R++ +L HL +S L I NF W+ T+I+ G Sbjct: 418 GGPCTGKTLLLAE-VAKQAYSCLQKEMGPETDPVVIVRFIGSSDLSTDLRNLLQSICEQI----AINYRCLIHFLPNKIQEMRELLVNLLGESSFQRPLVIILDALEQLSD-ADDARKLW-WLPIHLPRTVRIVVSTLPNKHGILQKLRCLIHD--DDCYVELMQRDRKACSQTLKQQLLSVKR-KVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFFSIENKLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDIMVSSNLKSP---LRISYDLIAQLKEELEGYL-VERQVRNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHHQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLDQDIFF-------------VNHRKMTELLFHLTRSGRTDDLMYGVIMNFSWLY-TMIKIG 876
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Cavefish
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:103039682]) HSP 1 Score: 70.8626 bits (172), Expect = 1.433e-11 Identity = 112/487 (23.00%), Postives = 205/487 (42.09%), Query Frame = 3 Query: 1839 SGPINGKTNLMCHLISAFQYNKLEHSIN---DYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLR-----IPEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSV--PKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFL---TNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYM--------------NNNYDRSVLFKSMDP-------------------DFILPNYP----LHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFG 3137 GP GKT L+ ++ Y+ L+ + D +VI R +G S +TD+ +L+S+C Q+ +N R +P I ++ LL +L F+ ++I LD +E + + +D+ ++ WLP+ + +++ ST I Q L + D D + + + + L + +S R T Q+ + + +C FV R W S V L + + +I F +E++ G + R LGY++ G++ VEL DI++ D+++ + +NL P S+ L+ + EL+ +L + L+ W + + A YL ++ H L++ Y++ NN++ + + +P D P P +++ QDIFF N R++ +L HL +S L I NF W+ T+I+ G Sbjct: 495 GGPCTGKTLLLAE-VAKQAYSCLQKEMGPETDPVVIVRFIGSSDLSTDLRNLLQSICEQI----AINYRCLIHFLPNKIQEMRELLVNLLGESSFQRPLVIILDALEQLSD-ADDARKLW-WLPIHLPRTVRIVVSTLPNKHGILQKLRCLIHD--DDCYVELMQRDRKACSQTLKQQLLSVKR-KVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFFSIENKLGSRFVFRALGYVTMARAGLTEVELEDILSLDNSVLGDIMVSSNLKSP---LRISYDLIAQLKEELEGYL-VERQVRNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHHQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLDQDIFF-------------VNHRKMTELLFHLTRSGRTDDLMYGVIMNFSWLY-TMIKIG 953
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO31117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYV4]) HSP 1 Score: 124.02 bits (310), Expect = 4.247e-28 Identity = 144/650 (22.15%), Postives = 277/650 (42.62%), Query Frame = 3 Query: 1851 NGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVC---CQLLYETKVNLRIPEDIIGL----KILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIY-SIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVP--KLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFS--LLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYY------YMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLN-LDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIG--VLYIWDN-SKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVS 3731 +GKT++M + AF+ E ++ + I+R LG S ++ ++SVC Q+ + + ED L LL+ + + + +++ LD ++ + N + NWLP + ++ K++ S P Y +L ++ SL + Y +P LS T ++ ++ T EQ+ ++++ ++C F+ A W S + V LG + I + F RLE + G+ + R L Y++ +G++ EL DI++ DD + + +P L V +++D FL G ++ W H + A YL K ++ + ++ + VL + LP+ + Q + F +E FN R++ +LP+HL+ S+ + L +FNF WI + +N V+ A +A+P D++ + LILS N+ + + Q++ R+ G+ + + L++ Y+ I N +P + P C+ SP + + + + C+ T FI T G ++ IW+ + + + ++ +G G ++L +V A WDI + + F CL V+ Sbjct: 376 SGKTSIMA--VIAFRVK--EWLGDNAVCIFRFLGTSPGTSNTLLTIKSVCEQIHQVFGLESLKEDVAEDYTELVRHFHELLSTLSVSAERPLVLVLDSVDQLSPSYN--AHLMNWLPKSLSDHIKIVISV---LPGYYEILPTLQRSLTDTNCYIEVPTLSRDTGHEILDAWLDSKHRTLTPEQRVLVMAAFDKCPQPLFLKLIFAEASEWASYTDVSGVSLGANVPEAIGFLFERLERKHGKMLFSRALQYVTAARSGLTENELEDILSLDDDVIDDVYQYWDPPVEGVVRLPNLLWARVRSDIDEFL-VERQADGKTVVAWYHRQFWEACERMYLKDGVKVDAHALMAEFFLGEFWTWGGGRKKHIVLTRRQKA---LPDADRQVSAQPLMFSKEI---------FNLRKLSELPYHLVHSKQFNALSQEVLFNFEWIMAKVKAQSLNSVLADYDTALQAKP-DLDIRLVQDTLILSSSNIKHDLNSLAPQLIGRLLAF------KGKFPRIASLLEQAYRWIYARN-IPVIAPMNACLISPGGPLITNLHGHTQRLDCV--TVTRDDKFIVTSGGDSLINIWNTENHDCIHTLKIG-GKGQSHLVLTNDDRFVVAAADSSFGAWDIDTGEKVVSFESHVKITCLAVT 992
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO34994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMT6]) HSP 1 Score: 83.5741 bits (205), Expect = 4.207e-16 Identity = 114/507 (22.49%), Postives = 223/507 (43.98%), Query Frame = 3 Query: 1323 QEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEE---------NQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSI--SLSNNPISCLISGPIN-GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQL--LYETKVNLRIPEDIIGLKILLNQILLM--IDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRH 2786 +E F + I+ L + + + L F D ++ L+ LL ++ ++ N Y++ + G +SP H +YI+++ ++Q +L+ I +AI E + SE+ + E + Q L F + +Q Y +E +L+ L LN + + N P+ +I G GKT+ ++S E D V+ R +G + ++ + ++RSVC Q+ +YE + I DI LK + L M ++ ++I LD ++ + D +WLP+ + ++ ++ ST + +K L S +P+L ++ Y+ + +Q++++ +++C FV + A W S S + + L + + I F R+E Q G ++ R LGY++ +G++ EL D+++ DD + + P +R + +L+S+L T G Q++ W H Sbjct: 161 RECCWFSRNIRDLEKHVADGRAHL----FIDTTREGDVDLEAQRLLGNLKKDLLHCYLPLDNVKTYDVTWSRDG-ISPNLNNEHRAYIERMCEDVQIVLQHLITNAI--ERRNSSEVTDPMFEEAL----QHLSFCQSKCEQFYGREDVLLS------CRLILNMRSYDVLDVCRNRPL--VIYGESGCGKTS----VVSMVAMRSREWLRGDTCVVVRYIGTTPDSSLVRLLVRSVCQQICAVYEKDPSF-IRNDIKELKEDFIRCLRMATVERPLLIVLDSLDQLS--AEDGARQLSWLPMTLPDHVHLVVSTIPE--VKYECFPVLKAFLPPESFVLVPKLPQKDAAEILVSYLRMEHRTLSTDQQDIVQQALQECSLPIFVRVAFDEAIRWKSYSPLDETVLQHTVRGAINSLFERVERQHGHVLVSRALGYVTAAKSGLTETELEDLLSCDDFVLDDVYQYWTPPVRRIPPLLWVR-IRQDLESYLVT-RGADGAQVVTWYH 637
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO40517 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Z9]) HSP 1 Score: 75.485 bits (184), Expect = 1.537e-13 Identity = 107/455 (23.52%), Postives = 196/455 (43.08%), Query Frame = 3 Query: 1467 INEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDY--LVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRI-PEDIIGLKILLNQILLMI--DFKVMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFD----DTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFL---GTFYDESGIQLIKWRH 2786 +++ N Y+++ G ++P H Y+ ++ +++K I DAI ++ E+ RD+ LF+E+A + L E F L + + IS S L GKT+L+ KL S +Y +V+ R LG + ++++ +LRS C QL + ++ P+D L L M + +++ LD + + +D++ M WLP K+ + V+ ST K P Y K LD + L + N++ ++S TD Q++++++ +C ++ + A W S + + K L ++ I F RLE + G ++R L YI+ G+S EL DI++ D D + ++ T V ++ +R EL+S++ GT G +++ W H Sbjct: 225 LDKSNIFSYDIKWTSEG-VTPEGNLTHGQYLGKLCTEFYDVMKKKITDAIT--KRAAGEV-----------RDKEHLFQEVAQHATFCN----LKCENFHGREDILEKIRTYISGSGQKPLVLYGDSGCGKTSLVAMTA------KLVPSWTEYEPVVVLRFLGTTPDSSNIRLVLRSACLQLCKAFGTSTKVVPQDYQDLLREFQDRLKMAKSNRPIVVILDSADQLTT-TDDAHQMV-WLPRKLPKHVYVLVSTLKD-PKYACYPALKKLLLDSNCFVEVSSLPSEVACNILTSWLSNDNRRLTDSQRKIVLNAFNRCPLPLYLRLAYDHAVTWKSYTPLEKSVLEKNVQGMIKALFKRLERRHGTVLVRHALAYITAAKHGLSEPELEDILSCDEEVLDEVFQYWTPPVR--RIPPLLWARIR---AELNSYVVECGT----DGARVVTWYH 643
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO37261 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG70]) HSP 1 Score: 72.0182 bits (175), Expect = 1.516e-12 Identity = 93/418 (22.25%), Postives = 186/418 (44.50%), Query Frame = 3 Query: 1410 TDKMMSENIQLQRNDLLKHINEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFSTEKSAP--IYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTS--SSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTI 2642 TD+M +Q ++ + + + N + Y+++ K G + P H Y++ + Q +LE I +I E SE+ S I E + Q ++F + + + + VLN + +L E + + C GKT++M ++A H + V+ R LG + +++ + ++++S+C Q+ ++ IP+ + + L +L K +++ LD ++ + D + +WLP + +CK+I ST A + L K+ D L I S+P L + V +++ ++ Q+++++S QC F+ S A W S +L + I R+E + G +++ LGY++ +G++ EL DI++ DD + Sbjct: 197 TDRM--SMLQQLKSSMKQILGINNMLVYKIKWTKKG-IDPTN-DEHRQYLNTFCRDFQRVLETKITQSI--SENTSSEIESPIYEEVV----QHMMFCQSKLDM-FHGRQAVLNS-----IGDYLREGLGQPLVLHGCSGC-------GKTSIMA--MAAKCARDWIHP--EACVVLRFLGTTPKSSTIRRLMKSICEQIKCVYRLTTSIPQGLKDMVELFPSLLASATAKRPLLVLLDSLDQLSP--EDGARLLDWLPKHLPGHCKMIVSTLPGAQYRCFPKLKAMFKN--DKLFI-SVPSLPHSDVSDILSMWLQQSGRTLQPAQRDLVMSAFSQCPLPLFLKISFDEACRWHSYTDPGQTRLYGSVRDAINGLLERIEAKHGRILVQHALGYLTAARSGLTETELDDILSSDDEV 582
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Nematostella
Match: EDO41687 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3R7]) HSP 1 Score: 63.929 bits (154), Expect = 5.481e-10 Identity = 93/411 (22.63%), Postives = 170/411 (41.36%), Query Frame = 3 Query: 1434 IQLQRNDLLKHINEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQIL--LFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLI----SGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNL-RIPEDIIGLKILLNQILLMID--FKVMIFLDGIENIKEYKNDSNSMFNWLPLKMNNCKVIFSTEKSAPIYQ-NLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTS----SSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIM 2624 + + ++++ + +N I Y + G + P H +YI ++ + L+ SI DAI +EK + ERD + LF++ QK K F FL + I NP ++ SG GKT++M + A V+YR LG S ++ +L S+C QL V L R+PED+ L L + L K+++ LD ++ + + +W P ++ + +F+ + P + L ++K L +P LS + +++ ++ QK ++ + C+ ++ + A W S S ++ K K N L F RLE G ++ ++ GYI+ +G++ EL D++ Sbjct: 194 VCVSQDEIATRLPRDNVITYNVHWSDEG-IDPESCEEHQNYIKELCDHFYDTLKGSIQDAIAEKEKTI-------------ERDSLAKELFDQGTFCQKKCK--------TFQGRKQFLGSIRERI---QNPRRIVVIHGESG--CGKTSIMAKV--AMVMRSWMTDPESCAVVYRFLGTSPDSSSTRLLLHSICSQLCRIAGVTLARVPEDLKSLSEYLPECLARASRQHKIVLVLDSLDQLT--GDTFGQELDWWPKQLPD--NVFAVLSTLPGEEYRCLPYLKALLPETCFMDVPVLSFHEADVILEGWLQEAGRCLQPHQKSAVLEAFKSCQLPLYLKLAFDEAIRWRSYTDKSETIVKKDVKGIINAL--FDRLERLHGRVLVSKVFGYITASRSGLTQPELDDLL 569
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 75.485 bits (184), Expect = 6.861e-13 Identity = 135/600 (22.50%), Postives = 239/600 (39.83%), Query Frame = 3 Query: 1665 ETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSIN---DYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLR-----IPEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSV--PKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDD------TIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYM--------------NNNYDRSVLFKSMDP----------------DFILPNYP----LHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFG-VNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIV 3299 ET P D++L L L E K + E L+ ++ S P+ + GP GKT L+ ++ Y L+ + D +VI R +G S +TD+ +L+S+C Q+ +N R +P I ++ LL +L F ++I LD +E + + D WLP+++ +++ ST I Q L + + D + + Q ++K + + T Q+ + + +C FV R W S V L + + +I F +E++ G+ + R LGYI+ G++ VEL DI++ D+ + +L N + S+ L+ + EL+ +L I L+ W + + A YL ++ H L++ Y++ NN++ + +P D P P ++++ DIFF N R++ +L +HL +S L I NF W+ T+I+ G + + LA E E FL L ++ NP S ++ R+ +V Sbjct: 357 ETDPLYDEVLQHLSLCKTYAALYEYKAETLDYVQEYLMPSKGSRMS------PM-VVFGGPCTGKTLLLSE-VAKQAYTWLQKEMGPETDPVVIVRFIGSSQLSTDLRTLLQSICEQI----AINYRCLIHFLPNKIQEMRELLINLLGESSFHRPLVIVLDSLEQLSD--ADEARKLWWLPIQLPRTVRIVVSTLPNKHGILQKLRHLIHDDGYYVELI---QRDRKACSQMLKQQLLGVKRKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDVIVATYLKNPLR------ISYDLVAKLREELEGYL-IERQVRNIALLVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFTYDNNHFTSLNISHHKNPHHQQSHEKASSDKYSYDRQTPEQPWVFQCNLLEPDIFF-------------VNHRKMTELVYHLTRSGRTDDLMFGVIMNFSWLY-TMIKIGQFEKALTDIDLAYSCSQEK-ELKFLATTLRGVKVKVLKNPASLSAELQQRLLPVV 917
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 74.7146 bits (182), Expect = 1.011e-12 Identity = 133/596 (22.32%), Postives = 238/596 (39.93%), Query Frame = 3 Query: 1665 ETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSIN---DYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLR-IPEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSV--PKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDD------TIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYM--------------NNNYDRSVLFKSMDP----------------DFILPNYP----LHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFG-VNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIV 3299 ET P D++L L L E K + E L+ ++ S P+ + GP GKT L+ ++ Y L+ + D +VI R +G S +TD+ +L+S+C Q+ + + +P I ++ LL +L F ++I LD +E + + D WLP+++ +++ ST I Q L + + D + + Q ++K + + T Q+ + + +C FV R W S V L + + +I F +E++ G+ + R LGYI+ G++ VEL DI++ D+ + +L N + S+ L+ + EL+ +L I L+ W + + A YL ++ H L++ Y++ NN++ + +P D P P ++++ DIFF N R++ +L +HL +S L I NF W+ T+I+ G + + LA E E FL L ++ NP S ++ R+ +V Sbjct: 367 ETDPLYDEVLQHLSLCKTYAALYEYKAETLDYVQEYLMPSKGSRMS------PM-VVFGGPCTGKTLLLSE-VAKQAYTWLQKEMGPETDPVVIVRFIGSSQLSTDLRTLLQSICEQIAINYRCLIHFLPNKIQEMRELLINLLGESSFHRPLVIVLDSLEQLSD--ADEARKLWWLPIQLPRTVRIVVSTLPNKHGILQKLRHLIHDDGYYVELI---QRDRKACSQMLKQQLLGVKRKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDVIVATYLKNPLR------ISYDLVAKLREELEGYL-IERQVRNIALLVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFTYDNNHFTSLNISHHKNPHHQQSHEKASSDKYSYDRQTPEQPWVFQCNLLEPDIFF-------------VNHRKMTELVYHLTRSGRTDDLMFGVIMNFSWLY-TMIKIGQFEKALTDIDLAYSCSQEK-ELKFLATTLRGVKVKVLKNPASLSAELQQRLLPVV 927
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Medaka
Match: nwd2 (NACHT and WD repeat domain containing 2 [Source:NCBI gene;Acc:101165765]) HSP 1 Score: 74.7146 bits (182), Expect = 1.011e-12 Identity = 133/596 (22.32%), Postives = 238/596 (39.93%), Query Frame = 3 Query: 1665 ETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSIN---DYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLR-IPEDIIGLKILLNQILLMIDFK--VMIFLDGIENIKEYKNDSNSMFNWLPLKM-NNCKVIFST-EKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSV--PKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDD------TIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYM--------------NNNYDRSVLFKSMDP----------------DFILPNYP----LHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFG-VNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIV 3299 ET P D++L L L E K + E L+ ++ S P+ + GP GKT L+ ++ Y L+ + D +VI R +G S +TD+ +L+S+C Q+ + + +P I ++ LL +L F ++I LD +E + + D WLP+++ +++ ST I Q L + + D + + Q ++K + + T Q+ + + +C FV R W S V L + + +I F +E++ G+ + R LGYI+ G++ VEL DI++ D+ + +L N + S+ L+ + EL+ +L I L+ W + + A YL ++ H L++ Y++ NN++ + +P D P P ++++ DIFF N R++ +L +HL +S L I NF W+ T+I+ G + + LA E E FL L ++ NP S ++ R+ +V Sbjct: 367 ETDPLYDEVLQHLSLCKTYAALYEYKAETLDYVQEYLMPSKGSRMS------PM-VVFGGPCTGKTLLLSE-VAKQAYTWLQKEMGPETDPVVIVRFIGSSQLSTDLRTLLQSICEQIAINYRCLIHFLPNKIQEMRELLINLLGESSFHRPLVIVLDSLEQLSD--ADEARKLWWLPIQLPRTVRIVVSTLPNKHGILQKLRHLIHDDGYYVELI---QRDRKACSQMLKQQLLGVKRKVTSGQQIYVNEALAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGQRFVFRALGYITMAKAGLTEVELEDILSLDNIVLGDVIVATYLKNPLR------ISYDLVAKLREELEGYL-IERQVRNIALLVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFTYDNNHFTSLNISHHKNPHHQQSHEKASSDKYSYDRQTPEQPWVFQCNLLEPDIFF-------------VNHRKMTELVYHLTRSGRTDDLMFGVIMNFSWLY-TMIKIGQFEKALTDIDLAYSCSQEK-ELKFLATTLRGVKVKVLKNPASLSAELQQRLLPVV 927
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Medaka
Match: nwd1 (NACHT and WD repeat domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-071116-8]) HSP 1 Score: 67.781 bits (164), Expect = 1.310e-10 Identity = 92/430 (21.40%), Postives = 177/430 (41.16%), Query Frame = 3 Query: 1854 GKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVC------CQLLYETKVNLRIPEDIIGLKILLNQILLMI---DFKVMIFLDGIENIKEYKNDSNSMFNWLPLKMN-NCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDE---SGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPL-----HIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLK 3083 GKT L+C ++ Q LE + LVI L Q + ++L S+C C L+ T + P + L+ IL + ++I LD +E + E + +W+P + ++ S + + + N+ DSL+ + + + +LS E +++ ++ + T EQK++ + + + L + WTS + + + LGN E + RLE + + ++ LGYI+ G+ EL D+M+ DD + + P S L + L L +E +G+ +I + H + + YL + + H+++ Y++ + + P LP L + Q ++F N R++ LPHHL+ + L++ L+ Sbjct: 352 GKTALLCKVVREMQ-RVLETRV--VLVIRFLAAHHPQRPALDQVLHSICLQVSSACGLVPPTPMTAGSPTE---LQKFFRNILEEASQQGYTLLIVLDALEQLAEQHHSHK--LHWIPTNLPPKVHLLVSMDTCSEAFVNM-RLKTDSLE--NFFEVERLSRDEGERIMESHLRASQRTLTAEQKDVALQSFTLTGCPLHLKLILSAVQNWTSFTPLTEQLLGNNTEEVMSQLLHRLEHKHRKELVGGALGYIALARDGLLEAELYDVMSLDDDVISEVYRYTHPPTPSLIRLPPL--LWARLKRDLKDHLEERWTNGVAVIAFNHRCLSEVVLGHYLTSERQG-RCHKILGEYFLGRWSGK------LKP-VALPGLSLLLSDRKVPPQPLWFAPGLA---------NIRKLQALPHHLLHAGLWEELR 751
BLAST of WD_REPEATS_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000064089.1 (SMESG000064089.1) HSP 1 Score: 3824.63 bits (9917), Expect = 0.000e+0 Identity = 1883/1883 (100.00%), Postives = 1883/1883 (100.00%), Query Frame = 3 Query: 36 MDYNSSNYLSPLGLLVKNSGKHPISLQGHYDHWVKYDGKKTYSVLPEQGIKAHLQRLRFQRSVTQLKLKRKKEKTIFLKKRSTFLNKSASKNGNGIFDFTDLYNDSIETGSTWWRITPLPDIVKQTETDTEKETVDFVQQPFIEASSIKTRIEALKHFSGSISNEVLNKYYNSRTIHIYVACSTFDMKNEISKLELNVWPHLRQLCLQYNRILVIHNLHNFSEELSSLGIQQYRKEIERSIEICSDQKSQHIKGLILFGDEYDEKDIPNYLLRDQIESIKSNMLPDIEKIMNLQSNIQSLKQRQSQIKQQNFKRENTVENFRENSFEDLNKSISKPTKITEIDKINAEIINCTSEIETLNYVTNIKLIDQWYHKANLTDNFYQLVSESEIIKDLKSPDFAKRKQARIIFKNIKTQLCAILSKYAANVLEQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKMNNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFETLDLVISRHLIIDTTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKHCSEMENIFDICEANELSRIFFASSKSGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKKKSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRPNPSVLSTSKSRLSXXXXXXXXXXXFISFGTANNTPVKQTSFLKASIHDLVIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAVILNNTATLASYFEKNQGLFLWKINNRIHHKLENSEANCCAEEFQDYRLEFLQEDSTLLAFNGSSFQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKENQAKINQVKKIENYLERNGI 5684 MDYNSSNYLSPLGLLVKNSGKHPISLQGHYDHWVKYDGKKTYSVLPEQGIKAHLQRLRFQRSVTQLKLKRKKEKTIFLKKRSTFLNKSASKNGNGIFDFTDLYNDSIETGSTWWRITPLPDIVKQTETDTEKETVDFVQQPFIEASSIKTRIEALKHFSGSISNEVLNKYYNSRTIHIYVACSTFDMKNEISKLELNVWPHLRQLCLQYNRILVIHNLHNFSEELSSLGIQQYRKEIERSIEICSDQKSQHIKGLILFGDEYDEKDIPNYLLRDQIESIKSNMLPDIEKIMNLQSNIQSLKQRQSQIKQQNFKRENTVENFRENSFEDLNKSISKPTKITEIDKINAEIINCTSEIETLNYVTNIKLIDQWYHKANLTDNFYQLVSESEIIKDLKSPDFAKRKQARIIFKNIKTQLCAILSKYAANVLEQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKMNNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFETLDLVISRHLIIDTTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKHCSEMENIFDICEANELSRIFFASSKSGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKKKSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRPNPSVLSTSKSRLSENNVYNNNENNFISFGTANNTPVKQTSFLKASIHDLVIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAVILNNTATLASYFEKNQGLFLWKINNRIHHKLENSEANCCAEEFQDYRLEFLQEDSTLLAFNGSSFQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKENQAKINQVKKIENYLERNGI Sbjct: 1 MDYNSSNYLSPLGLLVKNSGKHPISLQGHYDHWVKYDGKKTYSVLPEQGIKAHLQRLRFQRSVTQLKLKRKKEKTIFLKKRSTFLNKSASKNGNGIFDFTDLYNDSIETGSTWWRITPLPDIVKQTETDTEKETVDFVQQPFIEASSIKTRIEALKHFSGSISNEVLNKYYNSRTIHIYVACSTFDMKNEISKLELNVWPHLRQLCLQYNRILVIHNLHNFSEELSSLGIQQYRKEIERSIEICSDQKSQHIKGLILFGDEYDEKDIPNYLLRDQIESIKSNMLPDIEKIMNLQSNIQSLKQRQSQIKQQNFKRENTVENFRENSFEDLNKSISKPTKITEIDKINAEIINCTSEIETLNYVTNIKLIDQWYHKANLTDNFYQLVSESEIIKDLKSPDFAKRKQARIIFKNIKTQLCAILSKYAANVLEQEQTLFEQEIKLLTNIIMEKKCLLVSRTFTDKMMSENIQLQRNDLLKHINEENQIRYELELHKSGKLSPAQLRNHFSYIDQVAHNIQTILEKSILDAIKFEEKELSELCSSILVETIPERDQILLFEELAIQQKYLKERKVLNEEIFPEMLLFLNETQHSISLSNNPISCLISGPINGKTNLMCHLISAFQYNKLEHSINDYLVIYRLLGVSFQNTDMTKILRSVCCQLLYETKVNLRIPEDIIGLKILLNQILLMIDFKVMIFLDGIENIKEYKNDSNSMFNWLPLKMNNCKVIFSTEKSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPKLGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQLIKWRHLSYNNAAVSRYLLQKDKAPSYHQLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFDNLIDNPLQFSCQILSRVTDIVREDRQTGEVRKYLNLDELYKSIITNNWLPTLIPSKNCMRSPISSMFSLVGFFFGNVTCLLSNPTSTKLFITTDIGVLYIWDNSKNTLSSIILGIGNYVFQMILNESHNTLVMALPDLIEVWDIKEVKILKRFNVFYDSYCLTVSSDKSLFTAFFYGIFWISTWSFETLDLVISRHLIIDTTVNNKGEIISSNSCNKFIALTAVKYDNKAALIDIRNGEINPVLLWSKEKGSAITKVGISTNYYILCSRGFSPNNNESVIYYIDTFDIESLKNARRISGCLLDSVSTFSINGVGSHAITSNCHLQTNMTDMSIWNLETEEHKHCSEMENIFDICEANELSRIFFASSKSGKVFKLNIQSALQVAKSKTVTKRQNYTLRKYELNDQYIFLTNENNSVIEIYNMMRKKKSGFKSWRISNIVDNNDIMLPYQDKLIILSDKSFSPIVPDCKCVFQMIKIFDLKEGRIASKTKEVFIYPCREKEFVVLSEDLFIGLSDNRSHIVAWNLSAGQIQWRIRPNPSVLSTSKSRLSENNVYNNNENNFISFGTANNTPVKQTSFLKASIHDLVIDSVLVSKDLSTLIVAYFSPFLCVFSLTNKCHIGTLTGEFSLLDLSIASLTHNGYYLIHYCFNDTLSKACLSLWNCKSETQISHLTVRHNVLAVILNNTATLASYFEKNQGLFLWKINNRIHHKLENSEANCCAEEFQDYRLEFLQEDSTLLAFNGSSFQIWNIFDVGVSFVGKFQPDQLINSYTLCLNDNLIAFVLKGSNDIFSLKLLKENQAKINQVKKIENYLERNGI 1883
BLAST of WD_REPEATS_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 72.0182 bits (175), Expect = 4.740e-12 Identity = 110/499 (22.04%), Postives = 216/499 (43.29%), Query Frame = 3 Query: 1929 LVIYRLLGVSFQNTDMTKILRSVC--CQLLYETKVNLRIPEDIIGLKILLNQILLMIDF------KVMIFLDGIENIKEYKND-----SNSMFNWLPLKMN-NCKVIFS--TE----KSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQ---LIKWRHLSYNNAAVSRYLLQKDKAPSYH-QLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEPEDIEYPFLIKLLILSFD----NLIDNPLQFSCQILSRVTDIVREDRQTGEVRKY 3335 +++ R +G S ++ + ++L SVC QL Y+ KV R + LK L N ++ I ++I D I+ + + N SNS+ +W+P+ + +I S TE K ++QN L+ + ++ + ++ L ++L++ + TD Q ++IS + ++ +L A W S S+ + + + +E+ + + FA LE+++G ++ LGY++ G++ +EL D+++ D + + +P SG L +C+ + S L + + + W H + A+ RY+ + H ++ YY + N +++ ++ L I D I+EK R++ L HL++S+ L +C N ++ FGV +I ++K + P L K I D N+ D P Q Q+ I+ D+ +G ++ Y Sbjct: 481 VIVLRFIGTSMYSSSLHQLLFSVCFQIQLAYKLKVKFRKMTSLSSLKWLFNYLIQQISHYSYQQSPLIIIFDSIDQLFMFSNTLNESLSNSL-DWIPVPLPPGIHIIISLITENFESKCFQMFQNRLSEFQHKFIHINYFDDKEVV-LICQSLLEHK----KRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYHDP-PISGI-IRLPSLMCSRIHSDLSEYIIKKQTDDKVTLYWYHKQIHQCALKRYVKDLEILEILHKEMADYYAICGNIEKTCFLQNHKRK-------LEIKNADRLINNPPINEK------EPRKLHALSFHLVESRQNYELSKLCTANLKFLLSYAKCFGVQELILLLKSCEKVFPLSKIINILKKCFIFLQDVMETNIEDLPYQLLGQLKYLDKIIISHDKSSGSIKLY 958
BLAST of WD_REPEATS_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 67.3958 bits (163), Expect = 1.385e-10 Identity = 110/510 (21.57%), Postives = 217/510 (42.55%), Query Frame = 3 Query: 1929 LVIYRLLGVSFQNTDMTKILRSVC--CQLLYETKVNLRIPEDIIGLKILLNQILLMIDF------KVMIFLDGIENIKEYKND-----SNSMFNWLPLKMN-NCKVIFS--TE----KSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQ---LIKWRHLSYNNAAVSRYLLQKDKAPSYH-QLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEP-----------------------EDIEYPFLIKL-----LILSFDNLID-NPLQFSCQILSRVTD 3293 +++ R +G S ++ + ++L SVC QL Y+ KV R + LK L N ++ I ++I D I+ + + N SNS+ +W+P+ + +I S TE K ++QN L+ + ++ + ++ L ++L++ + TD Q ++IS + ++ +L A W S S+ + + + +E+ + + FA LE+++G ++ LGY++ G++ +EL D+++ D + + +P SG L +C+ + S L + + + W H + A+ RY+ + H ++ YY + N +++ ++ L I D I+EK R++ L HL++S+ L +C N ++ FGV +I ++K + P ED+ Y L +L +I+S D D NP+ + + +R D Sbjct: 452 VIVLRFIGTSMYSSSLHQLLFSVCFQIQLAYKLKVKFRKMTSLSSLKWLFNYLIQQISHYSYQQSPLIIIFDSIDQLFMFSNTLNESLSNSL-DWIPVPLPPGIHIIISLITENFESKCFQMFQNRLSEFQHKFIHINYFDDKEVV-LICQSLLEHK----KRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYHDP-PISGI-IRLPSLMCSRIHSDLSEYIIKKQTDDKVTLYWYHKQIHQCALKRYVKDLEILEILHKEMADYYAICGNIEKTCFLQNHKRK-------LEIKNADRLINNPPINEK------EPRKLHALSFHLVESRQNYELSKLCTANLKFLLSYAKCFGVQELILLLKSCEKVFPLSKIINILKKCFIFLQDVMETNIEDLPYQLLGQLKYLDKIIISHDKSSDKNPITYKIGLTAREVD 940
BLAST of WD_REPEATS_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 66.2402 bits (160), Expect = 3.156e-10 Identity = 97/445 (21.80%), Postives = 196/445 (44.04%), Query Frame = 3 Query: 1929 LVIYRLLGVSFQNTDMTKILRSVC--CQLLYETKVNLRIPEDIIGLKILLNQILLMIDF------KVMIFLDGIENIKEYKND-----SNSMFNWLPLKMN-NCKVIFS--TE----KSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQ---LIKWRHLSYNNAAVSRYLLQKDKAPSYH-QLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEP 3185 +++ R +G S ++ + ++L SVC QL Y+ KV R + LK L N ++ I ++I D I+ + + N SNS+ +W+P+ + +I S TE K ++QN L+ + ++ + ++ L ++L++ + TD Q ++IS + ++ +L A W S S+ + + + +E+ + + FA LE+++G ++ LGY++ G++ +EL D+++ D + + +P SG L +C+ + S L + + + W H + A+ RY+ + H ++ YY + N +++ ++ L I D I+EK R++ L HL++S+ L +C N ++ FGV +I ++K + P Sbjct: 452 VIVLRFIGTSMYSSSLHQLLFSVCFQIQLAYKLKVKFRKMTSLSSLKWLFNYLIQQISHYSYQQSPLIIIFDSIDQLFMFSNTLNESLSNSL-DWIPVPLPPGIHIIISLITENFESKCFQMFQNRLSEFQHKFIHINYFDDKEVV-LICQSLLEHK----KRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYHDP-PISGI-IRLPSLMCSRIHSDLSEYIIKKQTDDKVTLYWYHKQIHQCALKRYVKDLEILEILHKEMADYYAICGNIEKTCFLQNHKRK-------LEIKNADRLINNPPINEK------EPRKLHALSFHLVESRQNYELSKLCTANLKFLLSYAKCFGVQELILLLKSCEKVFP 875
BLAST of WD_REPEATS_REGION domain-containing protein vs. Planmine SMEST
Match: SMESG000074035.1 (SMESG000074035.1) HSP 1 Score: 66.2402 bits (160), Expect = 3.167e-10 Identity = 97/445 (21.80%), Postives = 196/445 (44.04%), Query Frame = 3 Query: 1929 LVIYRLLGVSFQNTDMTKILRSVC--CQLLYETKVNLRIPEDIIGLKILLNQILLMIDF------KVMIFLDGIENIKEYKND-----SNSMFNWLPLKMN-NCKVIFS--TE----KSAPIYQNLLNFMKDSLDMLSIYSIPQLSNLTVENLIKDYISFYRIPWTDEQKEMLISNIEQCKTIGFVISSLRIARAWTSSSSVPK--LGNKLETNILYYFARLEDQFGEPIIRRLLGYISCFSTGVSIVELLDIMTFDDTIQKFLTNLVEPGDFSGFSFSLLRCVCTELDSFLGTFYDESGIQ---LIKWRHLSYNNAAVSRYLLQKDKAPSYH-QLVSYYYMNNNYDRSVLFKSMDPDFILPNYPLHIVKQDIFFGREFIHEKTKKSKFNKRRILQLPHHLMQSQLYKLLKCVCIFNFHWIQPTLIEFGVNYVIEIVKLAAEAEP 3185 +++ R +G S ++ + ++L SVC QL Y+ KV R + LK L N ++ I ++I D I+ + + N SNS+ +W+P+ + +I S TE K ++QN L+ + ++ + ++ L ++L++ + TD Q ++IS + ++ +L A W S S+ + + + +E+ + + FA LE+++G ++ LGY++ G++ +EL D+++ D + + +P SG L +C+ + S L + + + W H + A+ RY+ + H ++ YY + N +++ ++ L I D I+EK R++ L HL++S+ L +C N ++ FGV +I ++K + P Sbjct: 481 VIVLRFIGTSMYSSSLHQLLFSVCFQIQLAYKLKVKFRKMTSLSSLKWLFNYLIQQISHYSYQQSPLIIIFDSIDQLFMFSNTLNESLSNSL-DWIPVPLPPGIHIIISLITENFESKCFQMFQNRLSEFQHKFIHINYFDDKEVV-LICQSLLEHK----KRTLTDLQMNLIISKLINNPRGLYIKLALEQAVTWKSYMSMEECIIKDCVESAVNFKFACLEEKYGLLLMSHALGYLTLGYNGLTEIELEDLLSLQDNVLNEVYQYHDP-PISGI-IRLPSLMCSRIHSDLSEYIIKKQTDDKVTLYWYHKQIHQCALKRYVKDLEILEILHKEMADYYAICGNIEKTCFLQNHKRK-------LEIKNADRLINNPPINEK------EPRKLHALSFHLVESRQNYELSKLCTANLKFLLSYAKCFGVQELILLLKSCEKVFP 904 The following BLAST results are available for this feature:
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 3
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of WD_REPEATS_REGION domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 2
BLAST of WD_REPEATS_REGION domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of WD_REPEATS_REGION domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 4
BLAST of WD_REPEATS_REGION domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015127 ID=SMED30015127|Name=WD_REPEATS_REGION domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5779bpback to top protein sequence of SMED30015127-orf-1 >SMED30015127-orf-1 ID=SMED30015127-orf-1|Name=SMED30015127-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1893bp MDYNSSNYLSPLGLLVKNSGKHPISLQGHYDHWVKYDGKKTYSVLPEQGIback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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