Eyes absent homolog

Overview


Name	Eyes absent homolog
Smed ID	SMED30015071
Length (bp)	1754

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Eyes absent homolog (SMED30015071) t-SNE clustered cells

Violin plots show distribution of expression levels for Eyes absent homolog (SMED30015071) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Eyes absent homolog (SMED30015071) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Eyes absent homolog (SMED30015071) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30015071

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30015071	SMESG000001561.1	SmedASXL_015190	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30015071	SMESG000001561.1	SmedASXL_015190	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30015071	SMESG000001561.1	dd_Smed_v4_11372_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30015071	SMESG000001561.1	dd_Smed_v4_11372_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30015071	SMESG000001561.1	dd_Smed_v4_11372_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30015071	SMESG000001561.1	dd_Smed_v4_11372_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30015071	SMESG000001561.1	dd_Smed_v4_11372_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015071	SMESG000040512.1 SMESG000003282.1 SMESG000001561.1	Contig52495	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015071	SMESG000040512.1 SMESG000003282.1 SMESG000001561.1	Contig52495	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015071	SMESG000001561.1	Contig46265	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30015071	SMESG000001561.1	Contig46265	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
head region	SMED30015071	SMESG000001561.1	dd_Smed_v6_11372_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
pharynx	SMED30015071	SMESG000001561.1	SMED30015071	smed_20140614	PMID:25254346 Scimone et al., 2014
protonephridia	SMED30015071	SMESG000001561.1	SMED30015071	smed_20140614	PMID:25254346 Scimone et al., 2014
eye	SMED30015071	SMESG000001561.1	SMED30015071	smed_20140614	PMID:25254346 Scimone et al., 2014
head region	SMED30015071	SMESG000001561.1	OX_Smed_1.0.11562	ox_Smed_v2	PMID:24238224 Kao et al., 2013
optic cup	SMED30015071	SMESG000001561.1	SMED30015071	smed_20140614	PMID:21852957 Lapan et al., 2011
trail cell	SMED30015071	SMESG000001561.1	SMED30015071	smed_20140614	PMID:21852957 Lapan et al., 2011
pharynx musculature	SMED30015071	SMESG000001561.1	dd_Smed_v4_11372_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018
oviduct	SMED30015071	SMESG000001561.1	SMED30015071	smed_20140614	PMID:279364

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Eyes absent homolog vs. Ensembl Human
Match: EYA1 (EYA transcriptional coactivator and phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3519])

HSP 1 Score: 465.307 bits (1196), Expect = 4.305e-158
Identity = 232/370 (62.70%), Postives = 265/370 (71.62%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSES---QSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A    VT+         SP     DS+S   +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWRISSHSD++ALHHAL L YL
Sbjct:  211 TSPTTPSTNATYQLQEPPSGITSQA----VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 558

[Close]

BLAST of Eyes absent homolog vs. Ensembl Human
Match: EYA1 (EYA transcriptional coactivator and phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3519])

HSP 1 Score: 465.307 bits (1196), Expect = 4.695e-158
Identity = 232/370 (62.70%), Postives = 265/370 (71.62%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSES---QSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A    VT+         SP     DS+S   +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWRISSHSD++ALHHAL L YL
Sbjct:  212 TSPTTPSTNATYQLQEPPSGITSQA----VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 559

[Close]

BLAST of Eyes absent homolog vs. Ensembl Human
Match: EYA1 (EYA transcriptional coactivator and phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3519])

HSP 1 Score: 466.077 bits (1198), Expect = 5.921e-158
Identity = 232/370 (62.70%), Postives = 265/370 (71.62%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSES---QSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A    VT+         SP     DS+S   +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWRISSHSD++ALHHAL L YL
Sbjct:  239 TSPTTPSTNATYQLQEPPSGITSQA----VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 586

[Close]

BLAST of Eyes absent homolog vs. Ensembl Human
Match: EYA1 (EYA transcriptional coactivator and phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3519])

HSP 1 Score: 466.077 bits (1198), Expect = 7.493e-158
Identity = 232/370 (62.70%), Postives = 265/370 (71.62%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSES---QSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A    VT+         SP     DS+S   +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWRISSHSD++ALHHAL L YL
Sbjct:  245 TSPTTPSTNATYQLQEPPSGITSQA----VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592

[Close]

BLAST of Eyes absent homolog vs. Ensembl Human
Match: EYA1 (EYA transcriptional coactivator and phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3519])

HSP 1 Score: 466.077 bits (1198), Expect = 7.493e-158
Identity = 232/370 (62.70%), Postives = 265/370 (71.62%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSES---QSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A    VT+         SP     DS+S   +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWRISSHSD++ALHHAL L YL
Sbjct:  245 TSPTTPSTNATYQLQEPPSGITSQA----VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592

[Close]

BLAST of Eyes absent homolog vs. Ensembl Celegans
Match: eya-1 (Eyes absent homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:O17670])

HSP 1 Score: 98.5969 bits (244), Expect = 1.253e-21
Identity = 76/304 (25.00%), Postives = 144/304 (47.37%), Query Frame = 3

Query:  840 RIFVWDLDETIIIFHSLLTGI-YAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELY--NSYRNNVGGL----------------LGTQKREHWLQLRQDIETLTD---NWLTLALKALTLISQRNNC-----VNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHAL 1670
            R+F+WD+D+  +I  + L  + +  ++   A+ +V+    ME +     +N    N+  E D  +I+D   D+                          T +  GP+      ++RG +D MR++A +Y   ++ Y  NS +N+V G                  G ++     Q    ++TL +    W   A + + L+ +++        NV+++   LV   A++++ GL     +ENIYS +K GKES FE+I SRFG+K +++ +  G D   +A++++ P W ++S++D+  L+ AL
Sbjct:  232 RVFIWDIDDIAVISRNYLASVTHTNEFYARAANSVSH--LMERIAL---NNFADVNEFLEGDITNIEDAVVDE--------------------------TTMDSGPID-----NLRG-LDVMRRVAPKYSAFRQFYTENSTKNDVAGFKQEQNGFNFELLERVGFGAREATELYQSAIQLQTLPNFGQRW-PCAQRCMDLVVEKSKLSAEKYANVVLSNDGLVLGAAQLMISGLNSSVPVENIYSISKQGKESVFEKIQSRFGKKCSFICITSG-DTANSAKRLNIPVWPLNSNTDLDKLYSAL 496

[Close]

BLAST of Eyes absent homolog vs. Ensembl Celegans
Match: eya-1 (Eyes absent homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:O17670])

HSP 1 Score: 98.2117 bits (243), Expect = 1.443e-21
Identity = 76/304 (25.00%), Postives = 144/304 (47.37%), Query Frame = 3

Query:  840 RIFVWDLDETIIIFHSLLTGI-YAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELY--NSYRNNVGGL----------------LGTQKREHWLQLRQDIETLTD---NWLTLALKALTLISQRNNC-----VNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHAL 1670
            R+F+WD+D+  +I  + L  + +  ++   A+ +V+    ME +     +N    N+  E D  +I+D   D+                          T +  GP+      ++RG +D MR++A +Y   ++ Y  NS +N+V G                  G ++     Q    ++TL +    W   A + + L+ +++        NV+++   LV   A++++ GL     +ENIYS +K GKES FE+I SRFG+K +++ +  G D   +A++++ P W ++S++D+  L+ AL
Sbjct:  198 RVFIWDIDDIAVISRNYLASVTHTNEFYARAANSVSH--LMERIAL---NNFADVNEFLEGDITNIEDAVVDE--------------------------TTMDSGPID-----NLRG-LDVMRRVAPKYSAFRQFYTENSTKNDVAGFKQEQNGFNFELLERVGFGAREATELYQSAIQLQTLPNFGQRW-PCAQRCMDLVVEKSKLSAEKYANVVLSNDGLVLGAAQLMISGLNSSVPVENIYSISKQGKESVFEKIQSRFGKKCSFICITSG-DTANSAKRLNIPVWPLNSNTDLDKLYSAL 462

[Close]

BLAST of Eyes absent homolog vs. Ensembl Fly
Match: eya (gene:FBgn0000320 transcript:FBtr0306113)

HSP 1 Score: 422.55 bits (1085), Expect = 4.042e-140
Identity = 202/343 (58.89%), Postives = 250/343 (72.89%), Query Frame = 3

Query:  657 AGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            +G  + ++T  + K   + G  +    S ++S  S  GNSE    P              ER+FVWDLDET+IIFH+LL+G YA +Y KD S+ + +  RMEE++F++AD H FFN++EECDQVHIDDVSSDDNGQDLS YNF  DGF          +    G P  L   T VRGGVDWMRKLAFRYR+IK++YNSYR NVG LLG  KRE WLQ+R +IE  TDNW TLALK L++ISQR NCVNVLVT+TQL PALAKVLL+GLGG+F IENIYSA+KIG E+C+ERI +RFGRKSTYVV+GDG +EETAA+ +++PFWRIS+HSDI AL+ AL +G+L
Sbjct:  358 SGGVATSKTTPTGKTGRARG-RRHQQPSPTRSTASDTGNSEAVKPP--------------ERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFH---------TNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL 676

[Close]

BLAST of Eyes absent homolog vs. Ensembl Fly
Match: eya (gene:FBgn0000320 transcript:FBtr0079335)

HSP 1 Score: 422.55 bits (1085), Expect = 4.410e-139
Identity = 202/343 (58.89%), Postives = 250/343 (72.89%), Query Frame = 3

Query:  657 AGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            +G  + ++T  + K   + G  +    S ++S  S  GNSE    P              ER+FVWDLDET+IIFH+LL+G YA +Y KD S+ + +  RMEE++F++AD H FFN++EECDQVHIDDVSSDDNGQDLS YNF  DGF          +    G P  L   T VRGGVDWMRKLAFRYR+IK++YNSYR NVG LLG  KRE WLQ+R +IE  TDNW TLALK L++ISQR NCVNVLVT+TQL PALAKVLL+GLGG+F IENIYSA+KIG E+C+ERI +RFGRKSTYVV+GDG +EETAA+ +++PFWRIS+HSDI AL+ AL +G+L
Sbjct:  448 SGGVATSKTTPTGKTGRARG-RRHQQPSPTRSTASDTGNSEAVKPP--------------ERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFH---------TNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL 766

[Close]

BLAST of Eyes absent homolog vs. Ensembl Fly
Match: eya (gene:FBgn0000320 transcript:FBtr0079334)

HSP 1 Score: 422.165 bits (1084), Expect = 5.806e-139
Identity = 202/343 (58.89%), Postives = 250/343 (72.89%), Query Frame = 3

Query:  657 AGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            +G  + ++T  + K   + G  +    S ++S  S  GNSE    P              ER+FVWDLDET+IIFH+LL+G YA +Y KD S+ + +  RMEE++F++AD H FFN++EECDQVHIDDVSSDDNGQDLS YNF  DGF          +    G P  L   T VRGGVDWMRKLAFRYR+IK++YNSYR NVG LLG  KRE WLQ+R +IE  TDNW TLALK L++ISQR NCVNVLVT+TQL PALAKVLL+GLGG+F IENIYSA+KIG E+C+ERI +RFGRKSTYVV+GDG +EETAA+ +++PFWRIS+HSDI AL+ AL +G+L
Sbjct:  442 SGGVATSKTTPTGKTGRARG-RRHQQPSPTRSTASDTGNSEAVKPP--------------ERVFVWDLDETLIIFHTLLSGSYANRYTKDHSSLMTIAFRMEEMVFNMADTHFFFNEIEECDQVHIDDVSSDDNGQDLSAYNFATDGFH---------TNTPPGAPPNLCLPTGVRGGVDWMRKLAFRYRKIKDIYNSYRGNVGTLLGPGKREAWLQIRSEIEVATDNWATLALKCLSMISQRENCVNVLVTSTQLAPALAKVLLFGLGGIFNIENIYSAHKIGHETCYERIVTRFGRKSTYVVIGDGNEEETAAKAMNFPFWRISAHSDIRALYTALDMGFL 760

[Close]

BLAST of Eyes absent homolog vs. Ensembl Zebrafish
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:ZFIN;Acc:ZDB-GENE-050327-93])

HSP 1 Score: 436.802 bits (1122), Expect = 2.501e-146
Identity = 210/303 (69.31%), Postives = 233/303 (76.90%), Query Frame = 3

Query:  786 NNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDD SSDDNGQDL  Y+F  DGF   A  AS+C                 T VRGGVDWMRKLAFRYRR+KELY +Y+NNVGGLLG  KRE WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG  F IENIYSA KIGKESCFERI SRFG   TYVV+GDG+DEE AA Q + PFWRISSHSD++ALH AL   YL
Sbjct:  332 NNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHAAATSASLCLA---------------TGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL 613

[Close]

BLAST of Eyes absent homolog vs. Ensembl Zebrafish
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:ZFIN;Acc:ZDB-GENE-050327-93])

HSP 1 Score: 436.417 bits (1121), Expect = 6.485e-146
Identity = 210/303 (69.31%), Postives = 233/303 (76.90%), Query Frame = 3

Query:  786 NNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDD SSDDNGQDL  Y+F  DGF   A  AS+C                 T VRGGVDWMRKLAFRYRR+KELY +Y+NNVGGLLG  KRE WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG  F IENIYSA KIGKESCFERI SRFG   TYVV+GDG+DEE AA Q + PFWRISSHSD++ALH AL   YL
Sbjct:  355 NNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHAAATSASLCLA---------------TGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL 636

[Close]

BLAST of Eyes absent homolog vs. Ensembl Zebrafish
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:ZFIN;Acc:ZDB-GENE-050327-93])

HSP 1 Score: 436.032 bits (1120), Expect = 8.553e-146
Identity = 210/303 (69.31%), Postives = 233/303 (76.90%), Query Frame = 3

Query:  786 NNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDD SSDDNGQDL  Y+F  DGF   A  AS+C                 T VRGGVDWMRKLAFRYRR+KELY +Y+NNVGGLLG  KRE WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG  F IENIYSA KIGKESCFERI SRFG   TYVV+GDG+DEE AA Q + PFWRISSHSD++ALH AL   YL
Sbjct:  357 NNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHAAATSASLCLA---------------TGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL 638

[Close]

BLAST of Eyes absent homolog vs. Ensembl Zebrafish
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:ZFIN;Acc:ZDB-GENE-050327-93])

HSP 1 Score: 433.721 bits (1114), Expect = 3.685e-145
Identity = 207/303 (68.32%), Postives = 232/303 (76.57%), Query Frame = 3

Query:  786 NNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDD SSDDNGQDL  Y+F  DGF   A  AS+C                 T VRGGVDWMRKLAFRYRR+KELY +Y+NNVGGLLG  KRE WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG  F IENIYSA KIGKESCFER+  RFGRK  YVV+GDG +EE AA + + PFWRISSHSD++ALH AL   YL
Sbjct:  332 NNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHAAATSASLCLA---------------TGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERVMQRFGRKVVYVVIGDGVEEEQAAAKHNMPFWRISSHSDLLALHQALEFEYL 613

[Close]

BLAST of Eyes absent homolog vs. Ensembl Zebrafish
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:ZFIN;Acc:ZDB-GENE-050327-93])

HSP 1 Score: 432.95 bits (1112), Expect = 1.304e-144
Identity = 207/303 (68.32%), Postives = 232/303 (76.57%), Query Frame = 3

Query:  786 NNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDD SSDDNGQDL  Y+F  DGF   A  AS+C                 T VRGGVDWMRKLAFRYRR+KELY +Y+NNVGGLLG  KRE WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG  F IENIYSA KIGKESCFER+  RFGRK  YVV+GDG +EE AA + + PFWRISSHSD++ALH AL   YL
Sbjct:  355 NNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPLAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDASSDDNGQDLGTYSFATDGFHAAATSASLCLA---------------TGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTSALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERVMQRFGRKVVYVVIGDGVEEEQAAAKHNMPFWRISSHSDLLALHQALEFEYL 636

[Close]

BLAST of Eyes absent homolog vs. Ensembl Xenopus
Match: EYA4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:100487615])

HSP 1 Score: 443.351 bits (1139), Expect = 1.835e-149
Identity = 222/361 (61.50%), Postives = 264/361 (73.13%), Query Frame = 3

Query:  603 STTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            S++  YQL +    L +  G    T    ++++  +P    DD   ++   +S     +  NNP P   SD      LER+F+WDLDETIIIFHSLLTG +AQKY KD+ TAV LGLRMEE+IF+LAD H+FFNDLEECDQVH+DDVSSDDNGQDLS+Y+F  DGF   AS             L LP  T VRGGVDWMRKLAFRYRR+KELYN+Y+NNVGGL G  KRE WLQLR D+E LTD+WL+ ALK+L+LIS R+N VNVLVTTTQL+PAL+KVLLY LGGVF IENIYSA K+GKESCFERI  RFGRK  YVV+GDG +EE AA++ + PFWRISSHSD++ALH AL L YL
Sbjct:  222 SSSSTYQLQDSLSGLTTQPGTDLQTGEFDAVQSPSTPIKDLDDRTCRTAGSKSRGRGRK--NNPSPPPDSD------LERVFIWDLDETIIIFHSLLTGTFAQKYGKDSPTAVTLGLRMEEMIFNLADAHLFFNDLEECDQVHVDDVSSDDNGQDLSSYSFATDGFRAAASSTT----------LCLP--TGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLFGPAKREAWLQLRADLEVLTDSWLSNALKSLSLISTRSNSVNVLVTTTQLIPALSKVLLYSLGGVFPIENIYSATKVGKESCFERIIQRFGRKVVYVVIGDGVEEEQAAKKNNMPFWRISSHSDLLALHQALELEYL 562

[Close]

BLAST of Eyes absent homolog vs. Ensembl Xenopus
Match: EYA4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:100487615])

HSP 1 Score: 442.58 bits (1137), Expect = 3.906e-149
Identity = 222/361 (61.50%), Postives = 264/361 (73.13%), Query Frame = 3

Query:  603 STTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            S++  YQL +    L +  G    T    ++++  +P    DD   ++   +S     +  NNP P   SD      LER+F+WDLDETIIIFHSLLTG +AQKY KD+ TAV LGLRMEE+IF+LAD H+FFNDLEECDQVH+DDVSSDDNGQDLS+Y+F  DGF   AS             L LP  T VRGGVDWMRKLAFRYRR+KELYN+Y+NNVGGL G  KRE WLQLR D+E LTD+WL+ ALK+L+LIS R+N VNVLVTTTQL+PAL+KVLLY LGGVF IENIYSA K+GKESCFERI  RFGRK  YVV+GDG +EE AA++ + PFWRISSHSD++ALH AL L YL
Sbjct:  226 SSSSTYQLQDSLSGLTTQPGTDLQTGEFDAVQSPSTPIKDLDDRTCRTAGSKSRGRGRK--NNPSPPPDSD------LERVFIWDLDETIIIFHSLLTGTFAQKYGKDSPTAVTLGLRMEEMIFNLADAHLFFNDLEECDQVHVDDVSSDDNGQDLSSYSFATDGFRAAASSTT----------LCLP--TGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLFGPAKREAWLQLRADLEVLTDSWLSNALKSLSLISTRSNSVNVLVTTTQLIPALSKVLLYSLGGVFPIENIYSATKVGKESCFERIIQRFGRKVVYVVIGDGVEEEQAAKKNNMPFWRISSHSDLLALHQALELEYL 566

[Close]

BLAST of Eyes absent homolog vs. Ensembl Xenopus
Match: EYA4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:100487615])

HSP 1 Score: 442.965 bits (1138), Expect = 6.224e-149
Identity = 211/301 (70.10%), Postives = 240/301 (79.73%), Query Frame = 3

Query:  783 NNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
             NNP P   SD      LER+F+WDLDETIIIFHSLLTG +AQKY KD+ TAV LGLRMEE+IF+LAD H+FFNDLEECDQVH+DDVSSDDNGQDLS+Y+F  DGF   AS             L LP  T VRGGVDWMRKLAFRYRR+KELYN+Y+NNVGGL G  KRE WLQLR D+E LTD+WL+ ALK+L+LIS R+N VNVLVTTTQL+PAL+KVLLY LGGVF IENIYSA K+GKESCFERI  RFGRK  YVV+GDG +EE AA++ + PFWRISSHSD++ALH AL L YL
Sbjct:  309 KNNPSPPPDSD------LERVFIWDLDETIIIFHSLLTGTFAQKYGKDSPTAVTLGLRMEEMIFNLADAHLFFNDLEECDQVHVDDVSSDDNGQDLSSYSFATDGFRAAASSTT----------LCLP--TGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLFGPAKREAWLQLRADLEVLTDSWLSNALKSLSLISTRSNSVNVLVTTTQLIPALSKVLLYSLGGVFPIENIYSATKVGKESCFERIIQRFGRKVVYVVIGDGVEEEQAAKKNNMPFWRISSHSDLLALHQALELEYL 591

[Close]

BLAST of Eyes absent homolog vs. Ensembl Xenopus
Match: EYA4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:100487615])

HSP 1 Score: 443.736 bits (1140), Expect = 7.991e-149
Identity = 222/361 (61.50%), Postives = 264/361 (73.13%), Query Frame = 3

Query:  603 STTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            S++  YQL +    L +  G    T    ++++  +P    DD   ++   +S     +  NNP P   SD      LER+F+WDLDETIIIFHSLLTG +AQKY KD+ TAV LGLRMEE+IF+LAD H+FFNDLEECDQVH+DDVSSDDNGQDLS+Y+F  DGF   AS             L LP  T VRGGVDWMRKLAFRYRR+KELYN+Y+NNVGGL G  KRE WLQLR D+E LTD+WL+ ALK+L+LIS R+N VNVLVTTTQL+PAL+KVLLY LGGVF IENIYSA K+GKESCFERI  RFGRK  YVV+GDG +EE AA++ + PFWRISSHSD++ALH AL L YL
Sbjct:  276 SSSSTYQLQDSLSGLTTQPGTDLQTGEFDAVQSPSTPIKDLDDRTCRTAGSKSRGRGRK--NNPSPPPDSD------LERVFIWDLDETIIIFHSLLTGTFAQKYGKDSPTAVTLGLRMEEMIFNLADAHLFFNDLEECDQVHVDDVSSDDNGQDLSSYSFATDGFRAAASSTT----------LCLP--TGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLFGPAKREAWLQLRADLEVLTDSWLSNALKSLSLISTRSNSVNVLVTTTQLIPALSKVLLYSLGGVFPIENIYSATKVGKESCFERIIQRFGRKVVYVVIGDGVEEEQAAKKNNMPFWRISSHSDLLALHQALELEYL 616

[Close]

BLAST of Eyes absent homolog vs. Ensembl Xenopus
Match: EYA4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:100487615])

HSP 1 Score: 443.736 bits (1140), Expect = 8.360e-149
Identity = 211/301 (70.10%), Postives = 240/301 (79.73%), Query Frame = 3

Query:  783 NNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
             NNP P   SD      LER+F+WDLDETIIIFHSLLTG +AQKY KD+ TAV LGLRMEE+IF+LAD H+FFNDLEECDQVH+DDVSSDDNGQDLS+Y+F  DGF   AS             L LP  T VRGGVDWMRKLAFRYRR+KELYN+Y+NNVGGL G  KRE WLQLR D+E LTD+WL+ ALK+L+LIS R+N VNVLVTTTQL+PAL+KVLLY LGGVF IENIYSA K+GKESCFERI  RFGRK  YVV+GDG +EE AA++ + PFWRISSHSD++ALH AL L YL
Sbjct:  340 KNNPSPPPDSD------LERVFIWDLDETIIIFHSLLTGTFAQKYGKDSPTAVTLGLRMEEMIFNLADAHLFFNDLEECDQVHVDDVSSDDNGQDLSSYSFATDGFRAAASSTT----------LCLP--TGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLFGPAKREAWLQLRADLEVLTDSWLSNALKSLSLISTRSNSVNVLVTTTQLIPALSKVLLYSLGGVFPIENIYSATKVGKESCFERIIQRFGRKVVYVVIGDGVEEEQAAKKNNMPFWRISSHSDLLALHQALELEYL 622

[Close]

BLAST of Eyes absent homolog vs. Ensembl Mouse
Match: Eya1 (EYA transcriptional coactivator and phosphatase 1 [Source:MGI Symbol;Acc:MGI:109344])

HSP 1 Score: 463.766 bits (1192), Expect = 1.408e-157
Identity = 227/367 (61.85%), Postives = 264/367 (71.93%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A      E + ++ +  +P    D    +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWR+SSHSD++ALHHAL L YL
Sbjct:  211 TSPTTPSTNATYQLQEPPSGVTSQAVTDPTAEYS-TIHSPSTPIKETDSERLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL 558

[Close]

BLAST of Eyes absent homolog vs. Ensembl Mouse
Match: Eya1 (EYA transcriptional coactivator and phosphatase 1 [Source:MGI Symbol;Acc:MGI:109344])

HSP 1 Score: 464.151 bits (1193), Expect = 2.179e-157
Identity = 227/367 (61.85%), Postives = 264/367 (71.93%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A      E + ++ +  +P    D    +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWR+SSHSD++ALHHAL L YL
Sbjct:  240 TSPTTPSTNATYQLQEPPSGVTSQAVTDPTAEYS-TIHSPSTPIKETDSERLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL 587

[Close]

BLAST of Eyes absent homolog vs. Ensembl Mouse
Match: Eya1 (EYA transcriptional coactivator and phosphatase 1 [Source:MGI Symbol;Acc:MGI:109344])

HSP 1 Score: 463.766 bits (1192), Expect = 3.861e-157
Identity = 227/367 (61.85%), Postives = 264/367 (71.93%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A      E + ++ +  +P    D    +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWR+SSHSD++ALHHAL L YL
Sbjct:  244 TSPTTPSTNATYQLQEPPSGVTSQAVTDPTAEYS-TIHSPSTPIKETDSERLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL 591

[Close]

BLAST of Eyes absent homolog vs. Ensembl Mouse
Match: Eya1 (EYA transcriptional coactivator and phosphatase 1 [Source:MGI Symbol;Acc:MGI:109344])

HSP 1 Score: 463.766 bits (1192), Expect = 3.861e-157
Identity = 227/367 (61.85%), Postives = 264/367 (71.93%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A      E + ++ +  +P    D    +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWR+SSHSD++ALHHAL L YL
Sbjct:  244 TSPTTPSTNATYQLQEPPSGVTSQAVTDPTAEYS-TIHSPSTPIKETDSERLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL 591

[Close]

BLAST of Eyes absent homolog vs. Ensembl Mouse
Match: Eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:MGI Symbol;Acc:MGI:1337104])

HSP 1 Score: 451.055 bits (1159), Expect = 8.355e-152
Identity = 221/321 (68.85%), Postives = 246/321 (76.64%), Query Frame = 3

Query:  723 KDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            KD  +   +S  S +      NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   AS  N          L LP  T VRGGVDWMRKLAFRYRR+KELYN+Y+NNVGGLLG  KR+ WLQLR +IE LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LGG F IENIYSA KIGKESCFERI SRFG   TYVV+GDG+DEE AA Q + PFWRISSHSD++ALH AL L YL
Sbjct:  314 KDLDDRTCRSSGSKSRGRGRKNNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSAN----------LCLP--TGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAANQHNMPFWRISSHSDLLALHQALELEYL 616

[Close]

BLAST of Eyes absent homolog vs. UniProt/SwissProt
Match: sp|Q99502|EYA1_HUMAN (Eyes absent homolog 1 OS=Homo sapiens OX=9606 GN=EYA1 PE=1 SV=2)

HSP 1 Score: 466.077 bits (1198), Expect = 3.598e-157
Identity = 232/370 (62.70%), Postives = 265/370 (71.62%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSES---QSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A    VT+         SP     DS+S   +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWRISSHSD++ALHHAL L YL
Sbjct:  245 TSPTTPSTNATYQLQEPPSGITSQA----VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592

[Close]

BLAST of Eyes absent homolog vs. UniProt/SwissProt
Match: sp|P97767|EYA1_MOUSE (Eyes absent homolog 1 OS=Mus musculus OX=10090 GN=Eya1 PE=1 SV=3)

HSP 1 Score: 463.766 bits (1192), Expect = 2.701e-156
Identity = 227/367 (61.85%), Postives = 264/367 (71.93%), Query Frame = 3

Query:  585 TNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            T+P+ PST   YQL   P  + S A      E + ++ +  +P    D    +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YN+Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKAL+LI  R NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE  A++ + PFWR+SSHSD++ALHHAL L YL
Sbjct:  244 TSPTTPSTNATYQLQEPPSGVTSQAVTDPTAEYS-TIHSPSTPIKETDSERLRRGSDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRVSSHSDLMALHHALELEYL 591

[Close]

BLAST of Eyes absent homolog vs. UniProt/SwissProt
Match: sp|O95677|EYA4_HUMAN (Eyes absent homolog 4 OS=Homo sapiens OX=9606 GN=EYA4 PE=1 SV=2)

HSP 1 Score: 454.521 bits (1168), Expect = 4.504e-152
Identity = 229/362 (63.26%), Postives = 263/362 (72.65%), Query Frame = 3

Query:  600 PSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            PS+T  YQL    P L +  G         ++++  +P   KD  E   +S  S +      NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   AS  N          L LP  T VRGGVDWMRKLAFRYRR+KELYN+Y+NNVGGLLG  KR+ WLQLR +IE LTD+WLT ALK+L++IS R+NC+NVLVTTTQL+PALAKVLLY LGG F IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE AA++ + PFWRISSHSD++ALH AL L YL
Sbjct:  304 PSSTSTYQLQESLPGLTNQPGEFD------TMQSPSTP--IKDLDERTCRSSGSKSRGRGRKNNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSAN----------LCLP--TGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639

[Close]

BLAST of Eyes absent homolog vs. UniProt/SwissProt
Match: sp|Q9Z191|EYA4_MOUSE (Eyes absent homolog 4 OS=Mus musculus OX=10090 GN=Eya4 PE=2 SV=2)

HSP 1 Score: 451.055 bits (1159), Expect = 5.844e-151
Identity = 221/321 (68.85%), Postives = 246/321 (76.64%), Query Frame = 3

Query:  723 KDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            KD  +   +S  S +      NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   AS  N          L LP  T VRGGVDWMRKLAFRYRR+KELYN+Y+NNVGGLLG  KR+ WLQLR +IE LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LGG F IENIYSA KIGKESCFERI SRFG   TYVV+GDG+DEE AA Q + PFWRISSHSD++ALH AL L YL
Sbjct:  314 KDLDDRTCRSSGSKSRGRGRKNNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSAN----------LCLP--TGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAANQHNMPFWRISSHSDLLALHQALELEYL 616

[Close]

BLAST of Eyes absent homolog vs. UniProt/SwissProt
Match: sp|O08575|EYA2_MOUSE (Eyes absent homolog 2 OS=Mus musculus OX=10090 GN=Eya2 PE=1 SV=1)

HSP 1 Score: 437.958 bits (1125), Expect = 5.643e-147
Identity = 220/380 (57.89%), Postives = 263/380 (69.21%), Query Frame = 3

Query:  570 SYCPPTNP-----SIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            SY PP  P     S P +T  Y L   P  +PS + + S+     +     +P    D       S     G S+ N++P P      A +NE+ER+FVWDLDETIIIFHSLLTG +A +Y KD +T+V +GL MEE+IF+LAD H+FFNDLE+CDQ+H+DDVSSDDNGQDLS YNF  DGF   A  AS+C G               T V GGVDWMRKLAFRYRR+KE+YN+YRNNVGGL+G  KRE WLQLR ++E LTD WLT +LKAL LI+ R NCVNVLVTTTQL+PALAKVLLYGLG VF IENIYSA K GKESCFERI  RFGRK+ Y+V+GDG +EE  A++ + PFWRIS H+D+ AL HAL L YL
Sbjct:  175 SYNPPYVPASSLCSSPLSTSTYVLQEAPHNVPSQS-SESLAGDYNTHNGPSTPAKEGDTERPHRASDGKLRGRSKRNSDPSP------AGDNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFNDLEDCDQIHVDDVSSDDNGQDLSTYNFSTDGFHSTAPGASLCLG---------------TGVHGGVDWMRKLAFRYRRVKEMYNTYRNNVGGLIGAPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYIVIGDGVEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 532

[Close]

BLAST of Eyes absent homolog vs. TrEMBL
Match: Q86FY6 (Eyes absent homolog OS=Dugesia japonica OX=6161 GN=eya PE=3 SV=1)

HSP 1 Score: 1050.43 bits (2715), Expect = 0.000e+0
Identity = 526/551 (95.46%), Postives = 540/551 (98.00%), Query Frame = 3

Query:   36 MFASSAATASLFGTNQPNXXXXXXXXXXYGLNNSEVAQQLVASVTASTSSYLSGYTDFEGVNSTACLDSTTDPNDVLTSSQAESLFNCALHQSGLYGQPYSMSSYLSDMPPTSEDNSLFASNFYNGLTGNYT-DQSQQQRNSAYVYAYGYSPYISAMYAGIHSPCQQIMNSMGSVVNTRSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            MFAS AATASLFGT+Q NP +FPSFMSSYGLNNSEVAQQLVASVTASTSSYL+GY+DFEG+NS ACLD+TTDPNDVLTSSQAESLFNCALHQSGLYGQPYSMSSYLSDMPPTSEDNSLFA+NFYNGLTGNY+ DQ+ QQRN AYVYAYGYSPYISAMYAGIHSPC QIMNSMGSVVN+RSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETA+SLKASESPGLSKDDSESQSKSPQSCNGNSETNNN GPKI S+I NENELERIFVWDLDETIIIFHSLLTGIYAQ+YQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQV+WPFWRISSHSDIVALHHALSLGYL
Sbjct:    1 MFASGAATASLFGTSQTNPPTFPSFMSSYGLNNSEVAQQLVASVTASTSSYLTGYSDFEGINSIACLDATTDPNDVLTSSQAESLFNCALHQSGLYGQPYSMSSYLSDMPPTSEDNSLFATNFYNGLTGNYSSDQAHQQRNPAYVYAYGYSPYISAMYAGIHSPCHQIMNSMGSVVNSRSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAVSLKASESPGLSKDDSESQSKSPQSCNGNSETNNNSGPKIPSEIVNENELERIFVWDLDETIIIFHSLLTGIYAQRYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVNWPFWRISSHSDIVALHHALSLGYL 551

[Close]

BLAST of Eyes absent homolog vs. TrEMBL
Match: T1E114 (Eyes absent homolog OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 596.66 bits (1537), Expect = 0.000e+0
Identity = 322/432 (74.54%), Postives = 359/432 (83.10%), Query Frame = 3

Query:   36 MFASSAATASLFGTNQPNXXXXXXXXXXYGLNNSEVAQQLVASVTASTSSYLSGYTDFEGVNSTACLDSTTDPNDVL-----TSSQAESLFNCALHQSGLYGQPYSMSSYLSDMPPTSEDNSLFASNFYNGLTGNY-TDQSQQQRNSAYVYAYGYSPYISAMYAGIHSPCQQIMNSMGSVVNTRSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLR 1313
            MF S + TASLFGTNQ N S+FPSFMSSY ++NSE   Q + S   ST+SYL  YTDF+  +ST    STTD NDVL     T+SQAESLFNCALHQS LY QPYSMS YL+DMP ++E +SLF SNFY+GL+G+Y TDQS  QR   YVY YGYSPYISAMYAGI+SPCQQIMNSM S+ NTR YC P+NPSIPSTTQKYQLINLPPA+PS AG+ +VTETAISLK S+SPG SKDD +S SKSP S  G S+ NNN   KI S+ +NE ELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADN+MFFNDLEECDQVHIDDVSSDDNGQDL+NYNFLVDGF+GP S+CNG   VIQGG LG+PG+T+VRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLG QK+   +  +
Sbjct:    1 MFGSGSTTASLFGTNQANSSTFPSFMSSYNMDNSE--GQHLPSTATSTTSYLGNYTDFDTTSSTTSAGSTTDTNDVLAASQLTTSQAESLFNCALHQSTLYNQPYSMSGYLADMPQSTEHSSLFGSNFYSGLSGSYNTDQSNSQRTHPYVYTYGYSPYISAMYAGINSPCQQIMNSMNSMANTRPYCGPSNPSIPSTTQKYQLINLPPAVPSMAGSTTVTETAISLKTSDSPGHSKDDCDSPSKSPLSGIGISDNNNNAMSKIPSEPSNETELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNNMFFNDLEECDQVHIDDVSSDDNGQDLTNYNFLVDGFSGPTSMCNG---VIQGG-LGIPGSTTVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGNQKKRSLVTTK 426

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BLAST of Eyes absent homolog vs. TrEMBL
Match: H6V054 (Eyes absent homolog (Fragment) OS=Schmidtea polychroa OX=50054 GN=eya PE=2 SV=1)

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 277/281 (98.58%), Postives = 279/281 (99.29%), Query Frame = 3

Query:  393 ASNFYNGLTGNYTDQSQQQRNSAYVYAYGYSPYISAMYAGIHSPCQQIMNSMGSVVNTRSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIK 1235
            ASNFYNGLTGNY+DQS QQRNSAYVYAYGYSPYISAMYAGIHSPCQQIMNSMGSVVN+RSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNN GPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIK
Sbjct:    1 ASNFYNGLTGNYSDQSHQQRNSAYVYAYGYSPYISAMYAGIHSPCQQIMNSMGSVVNSRSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNSGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIK 281

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BLAST of Eyes absent homolog vs. TrEMBL
Match: A0A433TNR0 (Eyes absent homolog OS=Elysia chlorotica OX=188477 GN=EGW08_009038 PE=3 SV=1)

HSP 1 Score: 485.723 bits (1249), Expect = 2.710e-164
Identity = 241/365 (66.03%), Postives = 284/365 (77.81%), Query Frame = 3

Query:  594 SIPSTTQKYQLINLPPALPSTAGNASVTE-TAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            ++PST Q YQL++ P +  ST G  + T+    +  AS SP L ++     S+S     G S T  +PGP        E++LER+FVWDLDETIIIFHSLLTG YAQ+Y KD   ++++GLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLSNYNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YNSYR+NVGGLLG+ KRE W+QLR +IETLTD+WLTLALK+L +IS R+NCVNVLVTTTQLVPALAKVLLYGLGGVF I+NIYSA KIGKESCFERI SRFGRK TYVVVGDG+DEE+A++Q++WPFWRIS+HSD+ ALHHAL LGYL
Sbjct:  129 TVPST-QTYQLLDTP-STTSTVGQPTATDGNNYNQLASPSPPLKENGQRGASRS----RGRSRTQPSPGP--------ESDLERVFVWDLDETIIIFHSLLTGSYAQRYTKDPQGSMSMGLRMEEVIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSNYNFATDGFHAAANNAN------------LCLATGVRGGVDWMRKLAFRYRRMKEIYNSYRSNVGGLLGSPKREQWMQLRHEIETLTDSWLTLALKSLQIISSRSNCVNVLVTTTQLVPALAKVLLYGLGGVFNIDNIYSATKIGKESCFERIVSRFGRKCTYVVVGDGRDEESASKQMNWPFWRISNHSDLAALHHALDLGYL 467

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BLAST of Eyes absent homolog vs. TrEMBL
Match: A0A1S3K8L1 (Eyes absent homolog OS=Lingula unguis OX=7574 GN=LOC106179425 PE=3 SV=1)

HSP 1 Score: 488.419 bits (1256), Expect = 2.485e-162
Identity = 252/424 (59.43%), Postives = 296/424 (69.81%), Query Frame = 3

Query:  420 GNYTDQSQQQRNSAYVYAY-GYSPYIS-AMYAGIHSPCQQIMNSMGSVVNTRSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            G YT Q        Y YAY GYS Y+S A  AG+ S                        + P +TQ Y+L++LPPA          T++  ++ +   P  ++ +  S+ +         + N +PGP        EN+LER+FVWDLDETIIIFHSLLTG YAQ+Y KD   +V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRRIKE+YNSYRNNVGGLLG QKR+ WLQLRQ+IE LTD+WL LALK+L +I+ R+NCVNVLVTTTQLVPALAKVLLYGLGGVF IENIYSA KIGKESCFERI SRFGRK TYVVVGDG+DEE AA+Q++WP+WR+S+HSD+ ALHHAL LGYL
Sbjct:  323 GGYTSQG------GYPYAYPGYSSYMSTADAAGLAS------------------------TSPPSTQTYKLVDLPPA---------TTDSQYNIPSPSPPLKAEANGRSRRRR--------QNNPSPGP--------ENDLERVFVWDLDETIIIFHSLLTGSYAQRYGKDPPQSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFQTDGFHAAATNAN------------LCLATGVRGGVDWMRKLAFRYRRIKEIYNSYRNNVGGLLGPQKRDQWLQLRQEIEALTDSWLNLALKSLQIINSRSNCVNVLVTTTQLVPALAKVLLYGLGGVFSIENIYSATKIGKESCFERIVSRFGRKCTYVVVGDGRDEEAAAKQMNWPYWRVSNHSDLAALHHALDLGYL 679

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BLAST of Eyes absent homolog vs. Ensembl Cavefish
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:ZFIN;Acc:ZDB-GENE-050327-93])

HSP 1 Score: 431.024 bits (1107), Expect = 5.046e-146
Identity = 210/305 (68.85%), Postives = 235/305 (77.05%), Query Frame = 3

Query:  783 NNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQR-NNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
             NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KDA  AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   A  AS+C                 T VRGGVDWMRKLAFRYRR+KELY +Y+NNVGGLLG  KRE WLQLR ++E LTD+WLT ALK+L++IS R +NCVNVLVTTTQL+PALAKVLLY LG  F IENIYSA KIGKESCFER+  RFGRK  YVV+GDG +EE AA + + PFWRISSHSD++ALH AL   YL
Sbjct:  193 KNNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDAPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAATSASLCLA---------------TGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTTALKSLSIISSRFDNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERVMQRFGRKVVYVVIGDGVEEEQAAAKHNMPFWRISSHSDLLALHQALEFEYL 476

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BLAST of Eyes absent homolog vs. Ensembl Cavefish
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:ZFIN;Acc:ZDB-GENE-050327-93])

HSP 1 Score: 431.409 bits (1108), Expect = 2.079e-145
Identity = 210/305 (68.85%), Postives = 235/305 (77.05%), Query Frame = 3

Query:  783 NNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQR-NNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
             NNP P   SD      LER+FVWDLDETII+FHSLLTG YAQKY KDA  AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   A  AS+C                 T VRGGVDWMRKLAFRYRR+KELY +Y+NNVGGLLG  KRE WLQLR ++E LTD+WLT ALK+L++IS R +NCVNVLVTTTQL+PALAKVLLY LG  F IENIYSA KIGKESCFER+  RFGRK  YVV+GDG +EE AA + + PFWRISSHSD++ALH AL   YL
Sbjct:  249 KNNPSPPPDSD------LERVFVWDLDETIIVFHSLLTGSYAQKYGKDAPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAATSASLCLA---------------TGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTTALKSLSIISSRFDNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERVMQRFGRKVVYVVIGDGVEEEQAAAKHNMPFWRISSHSDLLALHQALEFEYL 532

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BLAST of Eyes absent homolog vs. Ensembl Cavefish
Match: eya2 (EYA transcriptional coactivator and phosphatase 2 [Source:ZFIN;Acc:ZDB-GENE-040912-24])

HSP 1 Score: 426.017 bits (1094), Expect = 3.298e-144
Identity = 223/432 (51.62%), Postives = 288/432 (66.67%), Query Frame = 3

Query:  408 NGLTGNYTDQSQQQRNSAYVYAYG---YSPYISAMYAGIHSPCQQIMNSMGSVVNTRSYCPPTNPSIPST--TQKYQL-INLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            N +TG       QQ  SAY  +YG   YSPY +  Y   +     I  S  ++     Y  P +P++ ++   + +Q+  + PP+ P+                   PG  ++ + ++  S     G    N+ P P + SDI      ER+F+WDLDETIIIFHSLLTG ++ ++ KD++ AV+LGL MEE+IF+LAD+ +FFNDLEECDQVHIDDV+SDDNGQDLS YNF  DGF  PA           GG L L   + V GGVDWMRKLAFRYRR+KE+YN+++NNVGGLLG+ KRE WLQLR+++E LTD WLT ALKAL LI+ R NCVNV+VTTTQL+PAL+KVLLYGLGG F IENIYSA K GKESCFER++ RFGR++ YVV+GDG +EET A++ + PFWR++  +D+ AL HAL L YL
Sbjct:   78 NSITGTTPFSPTQQDFSAYS-SYGQSQYSPYYNTHYNNPYLTTSNI--SPSTITTAIPYQHPEHPAVTTSHSPESHQVEYHTPPSPPT-------------------PGKEQEGAPARRGSDGKLRGRKRAND-PVPPLDSDI------ERVFIWDLDETIIIFHSLLTGSFSTRFSKDSAKAVSLGLWMEEMIFNLADSRLFFNDLEECDQVHIDDVASDDNGQDLSTYNFGTDGFQSPAG----------GGALCL--GSGVHGGVDWMRKLAFRYRRVKEIYNTFKNNVGGLLGSPKREEWLQLRREMEALTDLWLTHALKALALINSRPNCVNVMVTTTQLIPALSKVLLYGLGGAFPIENIYSATKTGKESCFERVAQRFGRRAVYVVIGDGVEEETVAKKKNMPFWRVTCRADLEALSHALELDYL 468

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BLAST of Eyes absent homolog vs. Ensembl Cavefish
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:ZFIN;Acc:ZDB-GENE-050327-93])

HSP 1 Score: 425.631 bits (1093), Expect = 6.160e-142
Identity = 201/289 (69.55%), Postives = 228/289 (78.89%), Query Frame = 3

Query:  828 NELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGF---AGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            ++   +FVWDLDETII+FHSLLTG YAQKY KDA  AV LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   A  AS+C                 T VRGGVDWMRKLAFRYRR+KELY +Y+NNVGGLLG  KRE WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG  F IENIYSA KIGKESCFER+  RFGRK  YVV+GDG +EE AA + + PFWRISSHSD++ALH AL   YL
Sbjct:  348 DQFYLVFVWDLDETIIVFHSLLTGSYAQKYGKDAPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAATSASLCLA---------------TGVRGGVDWMRKLAFRYRRVKELYCTYKNNVGGLLGPAKREAWLQLRAEVEALTDSWLTTALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSAFPIENIYSATKIGKESCFERVMQRFGRKVVYVVIGDGVEEEQAAAKHNMPFWRISSHSDLLALHQALEFEYL 621

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BLAST of Eyes absent homolog vs. Ensembl Cavefish
Match: eya3 (eyes absent homolog 3 [Source:NCBI gene;Acc:103037529])

HSP 1 Score: 419.083 bits (1076), Expect = 2.567e-140
Identity = 217/400 (54.25%), Postives = 272/400 (68.00%), Query Frame = 3

Query:  540 NSMGSVVNTRSYCPPTN--PSIPSTT---------QKYQLINLPPALPSTAGNASVTETAISLKASESPGLS-------KDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            NS+G     + Y PP N  P+ P ++         Q Y  I    ++ +   + +VT  +++L A  +  +        +D  ES  ++P S           G K  S  + EN+LERIF+WDLDETIIIFHSLLTG +AQK+ KD +T + LGL+MEELIF LAD H+FFNDLEECDQVH++DV+SDDNGQDLSNYNF  DGF G A      ST            T V+GGV+WMRKLAFRYRR+KE+YN Y+ NVG LL   KRE  L++R +IET TD+WL+ A+K+L LI  R  C+NVLVTTTQLVPALAKVLLYGLG VF ++NIYSA KIGKESCFERI SRFG+K TYVV+GDG++EE AA+Q + PFWRIS+H D+V+LH AL L +L
Sbjct:  173 NSLGQNQFPQYYAPPANYLPAAPPSSEGDGAGVVVQNYTPIKTEDSVTAGLPSTTVTSPSVTLPAGAALPVGAPFSTAPRDQDESARRNPPS------KAKGKGKKPDSSQSTENDLERIFLWDLDETIIIFHSLLTGSFAQKFGKDPATVLNLGLQMEELIFELADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYNFASDGFNGAAGAGGPGST------------TGVQGGVEWMRKLAFRYRRLKEIYNGYKGNVGALLSPLKRELLLRVRSEIETATDSWLSTAIKSLLLIQSRGRCMNVLVTTTQLVPALAKVLLYGLGDVFPVDNIYSATKIGKESCFERIVSRFGKKVTYVVIGDGREEEFAAKQHNMPFWRISAHGDLVSLHQALELDFL 554

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BLAST of Eyes absent homolog vs. Ensembl Sea Lamprey
Match: eya1 (EYA transcriptional coactivator and phosphatase 1 [Source:ZFIN;Acc:ZDB-GENE-990712-18])

HSP 1 Score: 425.631 bits (1093), Expect = 1.396e-142
Identity = 216/336 (64.29%), Postives = 252/336 (75.00%), Query Frame = 3

Query:  690 SLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVG----GLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            +L++  +PG  K+  E   ++    +      NNP P    D      LER+F+WDLDETIIIFHSLLTG YA +Y KD  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQ LS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+YNSY+NNVG    GLLG  KR+ WLQLR +IE LTD+WLTLALK+L+L+  R+NC+NVLVTTTQLVPALAKVLLYGLG VF IENIYSA KIGKE+CFERI SRFGRK  YVVVGDG +EE A+++ + PFWRISSHSD++ALHHAL L YL
Sbjct:  310 TLQSPTTPG--KESEERTRRASGGKSRGRGRRNNPSPPPDGD------LERVFIWDLDETIIIFHSLLTGSYATRYGKDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQHLSTYNFATDGFHASATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYNSYKNNVGVVGAGLLGPPKRDAWLQLRAEIEALTDSWLTLALKSLSLVHSRSNCINVLVTTTQLVPALAKVLLYGLGIVFPIENIYSATKIGKENCFERIMSRFGRKVVYVVVGDGVEEEQASKKHNMPFWRISSHSDLMALHHALELEYL 625

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BLAST of Eyes absent homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010369.1 (pep scaffold:Pmarinus_7.0:GL478893:143469:150485:-1 gene:ENSPMAG00000009390.1 transcript:ENSPMAT00000010369.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 252.677 bits (644), Expect = 2.360e-81
Identity = 126/205 (61.46%), Postives = 148/205 (72.20%), Query Frame = 3

Query:  996 FFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQV 1610
            F +  EECDQ HIDDVS+DDNGQDL  YNF  DGF   +           GG  GL   T VRGG +WMRKLAFRYR IKE+YN+Y+NN+ GLLG  K E WLQL  +IE LT++WL LA K L+LI  R+N  NVLVTTTQL+PAL+KVLLYG G VF I NI+SA K+GKESCFERI S +GRK  YVV+GDG +EE  A++V
Sbjct:    1 FLSVFEECDQSHIDDVSADDNGQDLGTYNFATDGFCTASG---------SGG--GLCAATGVRGGSEWMRKLAFRYRHIKEIYNTYKNNLPGLLGPVKGEAWLQLLPEIENLTESWLMLAHKCLSLIHSRSNSENVLVTTTQLIPALSKVLLYGFGEVFPINNIFSATKMGKESCFERIVSHYGRKVIYVVIGDGVEEEQVAKKV 194

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BLAST of Eyes absent homolog vs. Ensembl Nematostella
Match: EDO37382 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG20])

HSP 1 Score: 434.491 bits (1116), Expect = 1.095e-150
Identity = 201/306 (65.69%), Postives = 249/306 (81.37%), Query Frame = 3

Query:  768 GNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            G   T++ P P++      ++ LERIF+WDLDETIIIFHSLLTG++A K+ KD+ ++VALGLRMEE+IF+LAD HMFFNDLE+CDQVHIDDV++DDNG DLS YNF  DGF   A+  N            L   T VRGGVDWMRKLA+RYR+IKE+Y+SYRNNVGGLLG  KRE WLQLR ++E+ TD+WLTLALKAL++I  R NC+N++VTTTQLVPALAK LLYGLG +F IENIYSA KIGKE+CFERI +RFG+K TY+VVGDG+DEETA+RQ+++PFWR+++HSD++ LHHAL LG+L
Sbjct:    3 GRRSTSSAPTPEL------DHSLERIFIWDLDETIIIFHSLLTGLFATKFGKDSPSSVALGLRMEEMIFNLADTHMFFNDLEDCDQVHIDDVAADDNGLDLSTYNFEADGFHAAATSAN------------LCMATGVRGGVDWMRKLAYRYRKIKEVYSSYRNNVGGLLGAAKRETWLQLRMELESTTDSWLTLALKALSIIHSRTNCLNIMVTTTQLVPALAKSLLYGLGALFPIENIYSATKIGKEACFERILNRFGKKCTYIVVGDGRDEETASRQMNFPFWRVNTHSDLINLHHALDLGHL 290

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BLAST of Eyes absent homolog vs. Ensembl Medaka
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:101171377])

HSP 1 Score: 448.358 bits (1152), Expect = 3.261e-151
Identity = 224/362 (61.88%), Postives = 263/362 (72.65%), Query Frame = 3

Query:  606 TTQKYQLINLPPALPSTAGNASVTETAI--SLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            +T  YQL +  PA+    G A+    A   ++++  +P    DD   +S   +S     + N +P P        +++LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IFSLAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KELY++Y+NNVGGLLG  KR+ WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG VF IENIYSA KIGKESCFERI SRFG   TYVV+GDGKDEE AA Q + PFWRISSHSD++ALH AL   YL
Sbjct:  250 STAAYQLQDPAPAM---TGQAAELHPADFDTVQSPSTPIKELDDRACRSGGSKSRGRGRKNNPSPAP--------DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFSLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKELYSTYKNNVGGLLGPAKRDAWLQLRAEVEALTDSWLTHALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSVFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGKDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL 588

[Close]

BLAST of Eyes absent homolog vs. Ensembl Medaka
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:101171377])

HSP 1 Score: 448.743 bits (1153), Expect = 4.293e-151
Identity = 224/362 (61.88%), Postives = 263/362 (72.65%), Query Frame = 3

Query:  606 TTQKYQLINLPPALPSTAGNASVTETAI--SLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            +T  YQL +  PA+    G A+    A   ++++  +P    DD   +S   +S     + N +P P        +++LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IFSLAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KELY++Y+NNVGGLLG  KR+ WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG VF IENIYSA KIGKESCFERI SRFG   TYVV+GDGKDEE AA Q + PFWRISSHSD++ALH AL   YL
Sbjct:  276 STAAYQLQDPAPAM---TGQAAELHPADFDTVQSPSTPIKELDDRACRSGGSKSRGRGRKNNPSPAP--------DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFSLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKELYSTYKNNVGGLLGPAKRDAWLQLRAEVEALTDSWLTHALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSVFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGKDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL 614

[Close]

BLAST of Eyes absent homolog vs. Ensembl Medaka
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:101171377])

HSP 1 Score: 447.588 bits (1150), Expect = 2.639e-150
Identity = 224/362 (61.88%), Postives = 263/362 (72.65%), Query Frame = 3

Query:  606 TTQKYQLINLPPALPSTAGNASVTETAI--SLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            +T  YQL +  PA+    G A+    A   ++++  +P    DD   +S   +S     + N +P P        +++LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IFSLAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KELY++Y+NNVGGLLG  KR+ WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG VF IENIYSA KIGKESCFERI SRFG   TYVV+GDGKDEE AA Q + PFWRISSHSD++ALH AL   YL
Sbjct:  304 STAAYQLQDPAPAM---TGQAAELHPADFDTVQSPSTPIKELDDRACRSGGSKSRGRGRKNNPSPAP--------DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFSLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKELYSTYKNNVGGLLGPAKRDAWLQLRAEVEALTDSWLTHALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSVFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGKDEEHAASQHNMPFWRISSHSDLLALHQALEFEYL 642

[Close]

BLAST of Eyes absent homolog vs. Ensembl Medaka
Match: eya4 (EYA transcriptional coactivator and phosphatase 4 [Source:NCBI gene;Acc:101171377])

HSP 1 Score: 445.662 bits (1145), Expect = 1.865e-149
Identity = 221/362 (61.05%), Postives = 263/362 (72.65%), Query Frame = 3

Query:  606 TTQKYQLINLPPALPSTAGNASVTETAI--SLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            +T  YQL +  PA+    G A+    A   ++++  +P    DD   +S   +S     + N +P P        +++LER+FVWDLDETII+FHSLLTG YAQKY KD   AV LGLRMEE+IFSLAD H+FFNDLEECDQVHIDDVSSDDNGQDLS Y+F  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KELY++Y+NNVGGLLG  KR+ WLQLR ++E LTD+WLT ALK+L++IS R+NCVNVLVTTTQL+PALAKVLLY LG VF IENIYSA KIGKESCFERI  RFGRK  YVV+GDG +EE AA++ + PFWRISSHSD++ALH AL   YL
Sbjct:  304 STAAYQLQDPAPAM---TGQAAELHPADFDTVQSPSTPIKELDDRACRSGGSKSRGRGRKNNPSPAP--------DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFSLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKELYSTYKNNVGGLLGPAKRDAWLQLRAEVEALTDSWLTHALKSLSIISSRSNCVNVLVTTTQLIPALAKVLLYSLGSVFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALEFEYL 642

[Close]

BLAST of Eyes absent homolog vs. Ensembl Medaka
Match: eya1 (EYA transcriptional coactivator and phosphatase 1 [Source:NCBI gene;Acc:100049367])

HSP 1 Score: 426.787 bits (1096), Expect = 1.110e-143
Identity = 219/349 (62.75%), Postives = 255/349 (73.07%), Query Frame = 3

Query:  648 PSTAGNASVTETAISLKASESPGLSKDDSES---QSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            P+   + ++T+         SP     DS+S   +  S     G    NNNP P   SD      LER+F+WDLDETII+FHSLLTG YA +Y +D  T+V+LGLRMEE+IF+LAD H+FFNDLEECDQVHIDDVSSDDNGQDLS YNF  DGF   A+  N            L   T VRGGVDWMRKLAFRYRR+KE+Y +Y+NNVGGLLG  KRE WLQLR +IE LTD+WLTLALKALTLI  R+NCVN+LVTTTQL+PALAKVLLYGLG VF IENIYSA KIGKESCFER+  RFGRK  Y+VVGDG +EE  +++ + PFWRISSHSD++ALHHAL L YL
Sbjct:  202 PTGITSQALTDNPAEYSTIHSPSTPIKDSDSDRLRRASDGKSRGRGRRNNNPSPPPDSD------LERVFIWDLDETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFSADGFHAAATSAN------------LCLATGVRGGVDWMRKLAFRYRRVKEIYTTYKNNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALTLIHSRSNCVNILVTTTQLIPALAKVLLYGLGVVFPIENIYSATKIGKESCFERVIQRFGRKVVYIVVGDGVEEEQGSKKHNMPFWRISSHSDLMALHHALDLEYL 532

[Close]

BLAST of Eyes absent homolog vs. Planmine SMEST
Match: SMESG000001561.1 (SMESG000001561.1)

HSP 1 Score: 1113.6 bits (2879), Expect = 0.000e+0
Identity = 549/550 (99.82%), Postives = 550/550 (100.00%), Query Frame = 3

Query:   36 MFASSAATASLFGTNQPNXXXXXXXXXXYGLNNSEVAQQLVASVTASTSSYLSGYTDFEGVNSTACLDSTTDPNDVLTSSQAESLFNCALHQSGLYGQPYSMSSYLSDMPPTSEDNSLFASNFYNGLTGNYTDQSQQQRNSAYVYAYGYSPYISAMYAGIHSPCQQIMNSMGSVVNTRSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 1685
            MFASSAATASLFGTNQPNPSSFPSFMSSYGLNNSEVAQQLVASVTASTSSYLSGYTDFEGVNSTACLDSTTDPNDVLTSSQAESLFNCALHQSGLYGQPYSMSSYLSDMPPTSEDNSLFASNFYNGLTGNYTDQSQQQRNSAYVYAYGYSPYISAMYAGIHSPCQQIMNSMGSVVN+RSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL
Sbjct:    1 MFASSAATASLFGTNQPNPSSFPSFMSSYGLNNSEVAQQLVASVTASTSSYLSGYTDFEGVNSTACLDSTTDPNDVLTSSQAESLFNCALHQSGLYGQPYSMSSYLSDMPPTSEDNSLFASNFYNGLTGNYTDQSQQQRNSAYVYAYGYSPYISAMYAGIHSPCQQIMNSMGSVVNSRSYCPPTNPSIPSTTQKYQLINLPPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETNNNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDASTAVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNFLVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIKELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQRNNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERISSRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL 550

The following BLAST results are available for this feature:

BLAST of Eyes absent homolog vs. Ensembl Human
BLAST of Eyes absent homolog vs. Ensembl Celegans
BLAST of Eyes absent homolog vs. Ensembl Fly
BLAST of Eyes absent homolog vs. Ensembl Zebrafish
BLAST of Eyes absent homolog vs. Ensembl Xenopus
BLAST of Eyes absent homolog vs. Ensembl Mouse
BLAST of Eyes absent homolog vs. UniProt/SwissProt
BLAST of Eyes absent homolog vs. TrEMBL
BLAST of Eyes absent homolog vs. Ensembl Cavefish
BLAST of Eyes absent homolog vs. Ensembl Sea Lamprey
BLAST of Eyes absent homolog vs. Ensembl Yeast
BLAST of Eyes absent homolog vs. Ensembl Nematostella
BLAST of Eyes absent homolog vs. Ensembl Medaka
BLAST of Eyes absent homolog vs. Planmine SMEST

BLAST of Eyes absent homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EYA1	4.305e-158	62.70	EYA transcriptional coactivator and phosphatase 1 ...	[more]
EYA1	4.695e-158	62.70	EYA transcriptional coactivator and phosphatase 1 ...	[more]
EYA1	5.921e-158	62.70	EYA transcriptional coactivator and phosphatase 1 ...	[more]
EYA1	7.493e-158	62.70	EYA transcriptional coactivator and phosphatase 1 ...	[more]
EYA1	7.493e-158	62.70	EYA transcriptional coactivator and phosphatase 1 ...	[more]

BLAST of Eyes absent homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
eya-1	1.253e-21	25.00	Eyes absent homolog 1 [Source:UniProtKB/Swiss-Pro...	[more]
eya-1	1.443e-21	25.00	Eyes absent homolog 1 [Source:UniProtKB/Swiss-Pro...	[more]

BLAST of Eyes absent homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
eya	4.042e-140	58.89	gene:FBgn0000320 transcript:FBtr0306113	[more]
eya	4.410e-139	58.89	gene:FBgn0000320 transcript:FBtr0079335	[more]
eya	5.806e-139	58.89	gene:FBgn0000320 transcript:FBtr0079334	[more]

BLAST of Eyes absent homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eya4	2.501e-146	69.31	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya4	6.485e-146	69.31	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya4	8.553e-146	69.31	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya4	3.685e-145	68.32	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya4	1.304e-144	68.32	EYA transcriptional coactivator and phosphatase 4 ...	[more]

BLAST of Eyes absent homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EYA4	1.835e-149	61.50	EYA transcriptional coactivator and phosphatase 4 ...	[more]
EYA4	3.906e-149	61.50	EYA transcriptional coactivator and phosphatase 4 ...	[more]
EYA4	6.224e-149	70.10	EYA transcriptional coactivator and phosphatase 4 ...	[more]
EYA4	7.991e-149	61.50	EYA transcriptional coactivator and phosphatase 4 ...	[more]
EYA4	8.360e-149	70.10	EYA transcriptional coactivator and phosphatase 4 ...	[more]

BLAST of Eyes absent homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Eya1	1.408e-157	61.85	EYA transcriptional coactivator and phosphatase 1 ...	[more]
Eya1	2.179e-157	61.85	EYA transcriptional coactivator and phosphatase 1 ...	[more]
Eya1	3.861e-157	61.85	EYA transcriptional coactivator and phosphatase 1 ...	[more]
Eya1	3.861e-157	61.85	EYA transcriptional coactivator and phosphatase 1 ...	[more]
Eya4	8.355e-152	68.85	EYA transcriptional coactivator and phosphatase 4 ...	[more]

BLAST of Eyes absent homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q99502\|EYA1_HUMAN	3.598e-157	62.70	Eyes absent homolog 1 OS=Homo sapiens OX=9606 GN=E...	[more]
sp\|P97767\|EYA1_MOUSE	2.701e-156	61.85	Eyes absent homolog 1 OS=Mus musculus OX=10090 GN=...	[more]
sp\|O95677\|EYA4_HUMAN	4.504e-152	63.26	Eyes absent homolog 4 OS=Homo sapiens OX=9606 GN=E...	[more]
sp\|Q9Z191\|EYA4_MOUSE	5.844e-151	68.85	Eyes absent homolog 4 OS=Mus musculus OX=10090 GN=...	[more]
sp\|O08575\|EYA2_MOUSE	5.643e-147	57.89	Eyes absent homolog 2 OS=Mus musculus OX=10090 GN=...	[more]

BLAST of Eyes absent homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q86FY6	0.000e+0	95.46	Eyes absent homolog OS=Dugesia japonica OX=6161 GN...	[more]
T1E114	0.000e+0	74.54	Eyes absent homolog OS=Dendrocoelum lacteum OX=278...	[more]
H6V054	0.000e+0	98.58	Eyes absent homolog (Fragment) OS=Schmidtea polych...	[more]
A0A433TNR0	2.710e-164	66.03	Eyes absent homolog OS=Elysia chlorotica OX=188477...	[more]
A0A1S3K8L1	2.485e-162	59.43	Eyes absent homolog OS=Lingula unguis OX=7574 GN=L...	[more]

BLAST of Eyes absent homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eya4	5.046e-146	68.85	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya4	2.079e-145	68.85	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya2	3.298e-144	51.62	EYA transcriptional coactivator and phosphatase 2 ...	[more]
eya4	6.160e-142	69.55	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya3	2.567e-140	54.25	eyes absent homolog 3 [Source:NCBI gene;Acc:103037...	[more]

BLAST of Eyes absent homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
eya1	1.396e-142	64.29	EYA transcriptional coactivator and phosphatase 1 ...	[more]
ENSPMAT00000010369.1	2.360e-81	61.46	pep scaffold:Pmarinus_7.0:GL478893:143469:150485:-...	[more]

BLAST of Eyes absent homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Eyes absent homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO37382	1.095e-150	65.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Eyes absent homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eya4	3.261e-151	61.88	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya4	4.293e-151	61.88	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya4	2.639e-150	61.88	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya4	1.865e-149	61.05	EYA transcriptional coactivator and phosphatase 4 ...	[more]
eya1	1.110e-143	62.75	EYA transcriptional coactivator and phosphatase 1 ...	[more]

BLAST of Eyes absent homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000001561.1	0.000e+0	99.82	SMESG000001561.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30015071 ID=SMED30015071|Name=Eyes absent homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=1754bp
TTTCGTTTTTTTTAATATAACATAAAAAATCTCGAATGTTTGCTAGTTCA
GCCGCAACTGCATCATTGTTTGGTACAAATCAACCGAATCCCTCCTCATT
TCCGTCATTTATGTCATCATATGGATTGAATAATTCTGAAGTAGCACAAC
AGTTGGTCGCTAGTGTTACGGCATCAACCAGTTCCTATTTATCCGGTTAT
ACGGATTTTGAAGGAGTTAATAGTACAGCGTGCTTAGATTCGACGACTGA
TCCGAATGATGTATTAACAAGCAGCCAAGCTGAAAGCTTATTTAATTGTG
CTCTTCATCAATCTGGTTTATATGGTCAGCCGTATTCTATGAGTAGTTAT
TTGTCTGATATGCCACCTACAAGTGAAGATAACTCGTTGTTTGCCTCGAA
CTTTTACAACGGACTTACAGGAAATTATACCGACCAGTCTCAGCAACAAC
GCAACTCAGCATATGTATACGCATATGGATATTCGCCCTACATATCGGCA
ATGTATGCTGGTATTCATTCACCGTGTCAACAAATCATGAACAGTATGGG
TTCGGTAGTTAATACTCGTTCATATTGTCCACCAACAAATCCTTCGATTC
CATCAACTACACAGAAATATCAGTTAATAAATTTGCCTCCGGCTCTTCCG
TCGACTGCAGGCAACGCATCTGTGACAGAAACTGCCATCTCTCTAAAAGC
GTCGGAATCTCCTGGCCTTTCGAAAGACGACTCAGAAAGTCAATCTAAAT
CACCGCAGAGTTGCAATGGCAATTCGGAAACGAACAACAATCCGGGCCCG
AAAATCCAGTCAGACATTGCCAATGAAAACGAACTGGAAAGAATTTTTGT
TTGGGATTTGGACGAGACTATCATAATTTTTCATTCTCTCCTTACAGGAA
TTTACGCTCAGAAATACCAAAAAGATGCTTCAACTGCAGTCGCTCTCGGT
TTACGGATGGAGGAACTTATTTTCAGTTTAGCTGACAATCACATGTTTTT
CAATGATTTAGAAGAATGCGATCAAGTACACATTGATGATGTGTCATCAG
ATGATAATGGACAAGACTTAAGCAATTACAATTTTCTTGTCGACGGATTT
GCTGGGCCTGCTAGTATTTGCAATGGAGTATCTACAGTGATCCAAGGTGG
ACCACTGGGACTTCCTGGAAACACCAGTGTGCGCGGAGGAGTTGATTGGA
TGAGGAAATTAGCGTTCCGTTATCGACGAATAAAAGAACTGTACAATTCT
TACAGAAACAATGTAGGAGGTTTATTAGGCACACAAAAACGGGAACACTG
GCTACAATTAAGGCAAGACATTGAAACTCTTACAGACAATTGGCTTACGT
TGGCTTTGAAAGCCTTAACACTAATATCTCAAAGAAACAACTGTGTTAAT
GTATTGGTCACAACTACACAATTGGTACCCGCACTGGCAAAGGTTTTACT
GTATGGCTTGGGGGGAGTATTTCAAATTGAGAATATTTATTCTGCAAACA
AAATAGGGAAAGAGAGCTGTTTCGAAAGAATTTCATCTAGATTCGGACGA
AAGAGCACATACGTTGTTGTTGGAGATGGAAAAGATGAAGAAACAGCTGC
CAGACAGGTTAGTTGGCCATTTTGGAGAATAAGTTCACATTCCGATATCG
TGGCACTTCACCACGCATTGAGTCTTGGTTACTTATAATTACACTTTGCT
TTTTAGTTTTTTTATTCATTTGAAATTAATACAACTTGTTTTAATCAAAA
AAAA

protein sequence of SMED30015071-orf-1

>SMED30015071-orf-1 ID=SMED30015071-orf-1|Name=SMED30015071-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=551bp
MFASSAATASLFGTNQPNPSSFPSFMSSYGLNNSEVAQQLVASVTASTSS
YLSGYTDFEGVNSTACLDSTTDPNDVLTSSQAESLFNCALHQSGLYGQPY
SMSSYLSDMPPTSEDNSLFASNFYNGLTGNYTDQSQQQRNSAYVYAYGYS
PYISAMYAGIHSPCQQIMNSMGSVVNTRSYCPPTNPSIPSTTQKYQLINL
PPALPSTAGNASVTETAISLKASESPGLSKDDSESQSKSPQSCNGNSETN
NNPGPKIQSDIANENELERIFVWDLDETIIIFHSLLTGIYAQKYQKDAST
AVALGLRMEELIFSLADNHMFFNDLEECDQVHIDDVSSDDNGQDLSNYNF
LVDGFAGPASICNGVSTVIQGGPLGLPGNTSVRGGVDWMRKLAFRYRRIK
ELYNSYRNNVGGLLGTQKREHWLQLRQDIETLTDNWLTLALKALTLISQR
NNCVNVLVTTTQLVPALAKVLLYGLGGVFQIENIYSANKIGKESCFERIS
SRFGRKSTYVVVGDGKDEETAARQVSWPFWRISSHSDIVALHHALSLGYL
*

Aliases

The feature 'Eyes absent homolog' has the following synonyms


Synonym
eya

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000036	eye
PLANA:0000075	optic cup
PLANA:0000095	trail cell
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0000205	oviduct
PLANA:0000418	head
PLANA:0000478	pharynx musculature

Vocabulary: **INTERPRO**
Term	Definition
IPR038102	EYA_dom_sf
IPR006545	EYA_dom
IPR028472	EYA_fam
IPR042577	EYA_dom_metazoan

Vocabulary: **molecular function**
Term	Definition
GO:0004721	phosphoprotein phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated
GO:0006470	protein dephosphorylation
GO:0007275	multicellular organism development
GO:0035335	peptidyl-tyrosine dephosphorylation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR038102	EYA domain superfamily	GENE3D	G3DSA:3.40.50.12350		coord: 268..550 e-value: 2.7E-132 score: 442.0
IPR006545	EYA domain	TIGRFAM	TIGR01658	TIGR01658	coord: 268..549 e-value: 4.5E-108 score: 359.1
None	No IPR available	SFLD	SFLDS00003	Haloacid_Dehalogenase	coord: 269..544 e-value: 7.4E-32 score: 105.5
None	No IPR available	SFLD	SFLDG01129	C1.5:_HAD,_Beta-PGM,_Phosphat	coord: 269..544 e-value: 7.4E-32 score: 105.5
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 222..258
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 229..258
IPR028472	Eyes absent family	PANTHER	PTHR10190	EYES ABSENT	coord: 71..550
IPR042577	EYA domain, metazoan	CDD	cd02601	HAD_Eya	coord: 267..550 e-value: 9.52079E-163 score: 461.576

Main menu

Eyes absent homolog

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Owlery

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