Protocadherin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30015050 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 171.4 bits (433), Expect = 6.582e-43 Identity = 171/643 (26.59%), Postives = 284/643 (44.17%), Query Frame = 3
Query: 75 DSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXX---XXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNT-YQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKL----TRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSA 1955
D+ NGV Y L+ ++ + + + +LD E + L + D G P SS L + ++D ND APKF +Y + E+ +G +++V A D + G +I Y + + + +D N+G I ++ P+ D+ L +V A D N K VV+ + D+N++ P I + + Q +G I E+ E V+ + V D+DEG+N V C + F L ++ +Y L+ +D EKV + I D+G P L ST L+V V+D N+ +FT+S ++ EN +++ + DA S + L S + L +++ +GEI++ LDRE+ Y+ + + + + T ATV V VLD NDN P+++ +F + EN +G + D D GEN+++ +S E+ +G D + + S D E + D G P + + +N+LDENDN P PS N SH + T+L ++V A D DS + L Y + + I +G I+L K+IE G + L ++V+D G P R +A
Sbjct: 196 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGT-NPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQ--DG----MANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDV----PFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIA-EITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGT--ATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLS---------VEQDNG--DFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPS------NTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 806 HSP 2 Score: 124.79 bits (312), Expect = 2.506e-28 Identity = 149/619 (24.07%), Postives = 265/619 (42.81%), Query Frame = 3
Query: 246 GQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFH-LNSSNNFNME-------SFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
G P+L Q I++ DIND P F + T + E+ +GS+ A DR++G G Y+L + F V+ D K+P + D LT++ D + + + ++D N++ P P Y E+ EN+P V + D D+G N +++ Q ++++ L +RL++NT + ++ +DRE +S L FS+ +D G + + V V D N+ P + R + ++ ++D + +S V ++ A++ + + N + F L +++ + ++ PLD EK Y I V+ N +S ++ V V+D+NDN P Q V ++F ENN P + ++ D D G N+ + S E + LF IS E +QVK S+D E + ++ + D G P +++VN+LD NDN+P+++ S ++N+ +S + + V ID D + ++ ++ + I TG I SL+ D E Y L+ D G P R++ +TI + +N
Sbjct: 147 GSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEE-----KQPQLIVMGNLDRERWDSYDLTIKVQDGGSP-PRASSALLRVTVLDTNDNAPKFE--------------RPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRL------LRLDRNT--GLITVQGPVDREDLST-LRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIR---GIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSG--NPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAF--PENNKPGEVIAEITASDADSGSNAELVYS---------LEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGM--------VTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDEN 709
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 171.4 bits (433), Expect = 8.593e-43 Identity = 171/643 (26.59%), Postives = 284/643 (44.17%), Query Frame = 3
Query: 75 DSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXX---XXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNT-YQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKL----TRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSA 1955
D+ NGV Y L+ ++ + + + +LD E + L + D G P SS L + ++D ND APKF +Y + E+ +G +++V A D + G +I Y + + + +D N+G I ++ P+ D+ L +V A D N K VV+ + D+N++ P I + + Q +G I E+ E V+ + V D+DEG+N V C + F L ++ +Y L+ +D EKV + I D+G P L ST L+V V+D N+ +FT+S ++ EN +++ + DA S + L S + L +++ +GEI++ LDRE+ Y+ + + + + T ATV V VLD NDN P+++ +F + EN +G + D D GEN+++ +S E+ +G D + + S D E + D G P + + +N+LDENDN P PS N SH + T+L ++V A D DS + L Y + + I +G I+L K+IE G + L ++V+D G P R +A
Sbjct: 196 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGT-NPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQ--DG----MANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG----DVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIA-EITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGT--ATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLS---------VEQDNG--DFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPS------NTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 806 HSP 2 Score: 125.176 bits (313), Expect = 2.019e-28 Identity = 149/619 (24.07%), Postives = 265/619 (42.81%), Query Frame = 3
Query: 246 GQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFH-LNSSNNFNME-------SFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
G P+L Q I++ DIND P F + T + E+ +GS+ A DR++G G Y+L + F V+ D K+P + D LT++ D + + + ++D N++ P P Y E+ EN+P V + D D+G N +++ Q ++++ L +RL++NT + ++ +DRE +S L FS+ +D G + + V V D N+ P + R + ++ ++D + +S V ++ A++ + + N + F L +++ + ++ PLD EK Y I V+ N +S ++ V V+D+NDN P Q V ++F ENN P + ++ D D G N+ + S E + LF IS E +QVK S+D E + ++ + D G P +++VN+LD NDN+P+++ S ++N+ +S + + V ID D + ++ ++ + I TG I SL+ D E Y L+ D G P R++ +TI + +N
Sbjct: 147 GSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEE-----KQPQLIVMGNLDRERWDSYDLTIKVQDGGSP-PRASSALLRVTVLDTNDNAPKFE--------------RPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRL------LRLDRNT--GLITVQGPVDREDLST-LRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIR---GIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSG--NPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAF--PENNKPGEVIAEITASDADSGSNAELVYS---------LEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGM--------VTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDEN 709
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH9 (protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]) HSP 1 Score: 149.058 bits (375), Expect = 7.066e-36 Identity = 155/592 (26.18%), Postives = 272/592 (45.95%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS-FVSIDGNSGTIILKKPLFDIDKLTL---TVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKD---IEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E+ VG+ ++++HA D + G +I Y +T +++ +G I +++ L D ++ + TV A D + ++ V I + DVN++ PNI D R +NG +Y + E +P N +++ I V DKD NG V C I+ + F+L K Y QY L +D E +F I D+G+P L T +++V + D+N+ P +F + LS+ E N+ + + + D+D+ + + L + +F L + +G + DRE+ R+ F++ A+DN S A V V VLD NDN P++ F + E N+P Y +G + D D GEN +++S L+ N++ +++ S D E + D+ D G P + + +N++D NDN P I P S + + ++ G+ + V A+D D+ + L Y + + ++ IDP TG I+L + + G + L + ++D G P
Sbjct: 218 YVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL-DREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNI----DLRYIISPINGT-VY---LSEKDPVNTKIALITVSDKDTDVNGKVICFIER----EVPFHL-------KAVYDNQYLLETSSLLDYEGTKE-FSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASF-------FDLDRKTGVLTASRVFDREEQERFIFTV----TARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE-NLPKYSTVGVITVTDADAGENKAVTLS-----------ILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS-NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761 HSP 2 Score: 73.9442 bits (180), Expect = 1.124e-12 Identity = 135/599 (22.54%), Postives = 246/599 (41.07%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC--QIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPA------LFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
K+ I + D ND AP F + + E+ + S A D ++G G Y+L+ + F V + +G ++ + D D + ++ D K + + + DVN++RP G + + I EN P V ++ D D G N +++ Q K LF L++ L + +++S+DRE+ + ++ D ++T+ ++V D N+ P + + N ++ + E KD N I V D+D + F E + FHL ++ + + + LD E + + F I + + + T A V V + D NDN P Q V +S + ENN L + D+D G+N+ I +L N F + + +L + D E + D G P ++ ++IV +LDENDN P++ + ++ N+ + + + DAD+ + +T + +D+ +DP++G I +++ D E Y ++ TD G P R+S+A +TI + N
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQ-KSSTAILQVTVSDVNDNRPVFKEGQVE--------------VHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGL--------ITVQRSLDREETAI-HKVTVLASDGSSTPARATV--TINVTDVNDNPPNIDLRYIISPINGTVYLSE-KDPVNTKIALITVSDKDTDVNGKVICFIEREV---------PFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQT--ALVRVKLEDENDNPPIFNQPVIELS--VSENNRRGLYLTTISATDEDSGKNADI------------VYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH----NHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVN 669 HSP 3 Score: 68.9366 bits (167), Expect = 4.481e-11 Identity = 71/275 (25.82%), Postives = 119/275 (43.27%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDI---DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE 1010
DYE +F +++A D G+P L + + + + D ND P F V E+ G + + A D +SG I+Y+L N SF +D +G + + +FD ++ TV A D+ + V++ ++D N++ P + + + +F+ EN P+ V I V D D G+N V I + F LD Y ++ S DRE+ S+ F + D GQP ST + ++V+D N+
Sbjct: 428 DYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPN----ASFFDLDRKTGVLTASR-VFDREEQERFIFTVTARDNGTPPLQ-SQAAVIVTVLDENDNSP------------KFTHNHFQFFVS--ENLPKYSTVGVITVTDADAGENKAVTLSILND---NDNFVLDP--------YSGVIKSNVSFDREQQSS-YTFDVKATDGGQPPRSSTAKVTINVMDVND 670
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH9 (protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]) HSP 1 Score: 148.673 bits (374), Expect = 1.044e-35 Identity = 155/592 (26.18%), Postives = 272/592 (45.95%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS-FVSIDGNSGTIILKKPLFDIDKLTL---TVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKD---IEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E+ VG+ ++++HA D + G +I Y +T +++ +G I +++ L D ++ + TV A D + ++ V I + DVN++ PNI D R +NG +Y + E +P N +++ I V DKD NG V C I+ + F+L K Y QY L +D E +F I D+G+P L T +++V + D+N+ P +F + LS+ E N+ + + + D+D+ + + L + +F L + +G + DRE+ R+ F++ A+DN S A V V VLD NDN P++ F + E N+P Y +G + D D GEN +++S L+ N++ +++ S D E + D+ D G P + + +N++D NDN P I P S + + ++ G+ + V A+D D+ + L Y + + ++ IDP TG I+L + + G + L + ++D G P
Sbjct: 218 YVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL-DREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNI----DLRYIISPINGT-VY---LSEKDPVNTKIALITVSDKDTDVNGKVICFIER----EVPFHL-------KAVYDNQYLLETSSLLDYEGTKE-FSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASF-------FDLDRKTGVLTASRVFDREEQERFIFTV----TARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE-NLPKYSTVGVITVTDADAGENKAVTLS-----------ILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS-NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761 HSP 2 Score: 74.7146 bits (182), Expect = 8.058e-13 Identity = 135/599 (22.54%), Postives = 246/599 (41.07%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC--QIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPA------LFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
K+ I + D ND AP F + + E+ + S A D ++G G Y+L+ + F V + +G ++ + D D + ++ D K + + + DVN++RP G + + I EN P V ++ D D G N +++ Q K LF L++ L + +++S+DRE+ + ++ D ++T+ ++V D N+ P + + N ++ + E KD N I V D+D + F E + FHL ++ + + + LD E + + F I + + + T A V V + D NDN P Q V +S + ENN L + D+D G+N+ I +L N F + + +L + D E + D G P ++ ++IV +LDENDN P++ + ++ N+ + + + DAD+ + +T + +D+ +DP++G I +++ D E Y ++ TD G P R+S+A +TI + N
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQ-KSSTAILQVTVSDVNDNRPVFKEGQVE--------------VHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGL--------ITVQRSLDREETAI-HKVTVLASDGSSTPARATVT--INVTDVNDNPPNIDLRYIISPINGTVYLSE-KDPVNTKIALITVSDKDTDVNGKVICFIEREV---------PFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQT--ALVRVKLEDENDNPPIFNQPVIELS--VSENNRRGLYLTTISATDEDSGKNADI------------VYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH----NHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVN 669 HSP 3 Score: 69.3218 bits (168), Expect = 3.034e-11 Identity = 71/275 (25.82%), Postives = 118/275 (42.91%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDI---DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE 1010
DYE +F +++A D G+P L + + + + D ND P F V E+ G + + A D +SG I+Y+L N SF +D +G + + +FD ++ TV A D+ + V++ ++D N++ P + N + + + EN P+ V I V D D G+N V I + F LD Y ++ S DRE+ S+ F + D GQP ST + ++V+D N+
Sbjct: 428 DYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPN----ASFFDLDRKTGVLTASR-VFDREEQERFIFTVTARDNGTPPLQ-SQAAVIVTVLDENDNSPKFT-----------HNHFQFF---VSENLPKYSTVGVITVTDADAGENKAVTLSILND---NDNFVLDP--------YSGVIKSNVSFDREQQSS-YTFDVKATDGGQPPRSSTAKVTINVMDVND 670
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH9 (protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]) HSP 1 Score: 148.673 bits (374), Expect = 1.170e-35 Identity = 155/592 (26.18%), Postives = 272/592 (45.95%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS-FVSIDGNSGTIILKKPLFDIDKLTL---TVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKD---IEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E+ VG+ ++++HA D + G +I Y +T +++ +G I +++ L D ++ + TV A D + ++ V I + DVN++ PNI D R +NG +Y + E +P N +++ I V DKD NG V C I+ + F+L K Y QY L +D E +F I D+G+P L T +++V + D+N+ P +F + LS+ E N+ + + + D+D+ + + L + +F L + +G + DRE+ R+ F++ A+DN S A V V VLD NDN P++ F + E N+P Y +G + D D GEN +++S L+ N++ +++ S D E + D+ D G P + + +N++D NDN P I P S + + ++ G+ + V A+D D+ + L Y + + ++ IDP TG I+L + + G + L + ++D G P
Sbjct: 218 YVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL-DREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNI----DLRYIISPINGT-VY---LSEKDPVNTKIALITVSDKDTDVNGKVICFIER----EVPFHL-------KAVYDNQYLLETSSLLDYEGTKE-FSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASF-------FDLDRKTGVLTASRVFDREEQERFIFTV----TARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE-NLPKYSTVGVITVTDADAGENKAVTLS-----------ILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS-NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761 HSP 2 Score: 74.7146 bits (182), Expect = 7.575e-13 Identity = 135/599 (22.54%), Postives = 246/599 (41.07%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC--QIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPA------LFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
K+ I + D ND AP F + + E+ + S A D ++G G Y+L+ + F V + +G ++ + D D + ++ D K + + + DVN++RP G + + I EN P V ++ D D G N +++ Q K LF L++ L + +++S+DRE+ + ++ D ++T+ ++V D N+ P + + N ++ + E KD N I V D+D + F E + FHL ++ + + + LD E + + F I + + + T A V V + D NDN P Q V +S + ENN L + D+D G+N+ I +L N F + + +L + D E + D G P ++ ++IV +LDENDN P++ + ++ N+ + + + DAD+ + +T + +D+ +DP++G I +++ D E Y ++ TD G P R+S+A +TI + N
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQ-KSSTAILQVTVSDVNDNRPVFKEGQVE--------------VHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGL--------ITVQRSLDREETAI-HKVTVLASDGSSTPARATVT--INVTDVNDNPPNIDLRYIISPINGTVYLSE-KDPVNTKIALITVSDKDTDVNGKVICFIEREV---------PFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQT--ALVRVKLEDENDNPPIFNQPVIELS--VSENNRRGLYLTTISATDEDSGKNADI------------VYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH----NHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVN 669 HSP 3 Score: 69.3218 bits (168), Expect = 2.926e-11 Identity = 71/275 (25.82%), Postives = 118/275 (42.91%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDI---DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE 1010
DYE +F +++A D G+P L + + + + D ND P F V E+ G + + A D +SG I+Y+L N SF +D +G + + +FD ++ TV A D+ + V++ ++D N++ P + N + + + EN P+ V I V D D G+N V I + F LD Y ++ S DRE+ S+ F + D GQP ST + ++V+D N+
Sbjct: 428 DYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPN----ASFFDLDRKTGVLTASR-VFDREEQERFIFTVTARDNGTPPLQ-SQAAVIVTVLDENDNSPKFT-----------HNHFQFF---VSENLPKYSTVGVITVTDADAGENKAVTLSILND---NDNFVLDP--------YSGVIKSNVSFDREQQSS-YTFDVKATDGGQPPRSSTAKVTINVMDVND 670
BLAST of Protocadherin vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 121.709 bits (304), Expect = 1.169e-27 Identity = 150/610 (24.59%), Postives = 279/610 (45.74%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHD---SAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIP-SYEL--GQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL----KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWI--YPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + K +L++ A + P + +S +V+ ++D+ D +P F +Y ++ED +G+ +L V A D +SG+ G+I Y L E + ++I+ SG I PL D+ TL++ D S + K + T +V I ++DVN++ P + S Y + I EN ++ + D+D G NG V + ++ + L ++ +T + LR R ID + ++P+ I +D QP L ST+ L ++V+D N++ + +++ EN + ID+D+ N ++ME + + SG I+ LDRE + RY S+ V + T++VV+ DINDN P +F+ KE N+ S E+ G I K + + I+ Y E + ++F I ++ IL V + + H +++I D+G + +VN+ ++ N + +P S+ + S I G + ++A D D + R+ Y + + IDP +G+IS++ D+ + + + + +D+ +P N+S + +I+
Sbjct: 229 DREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSL--GEGNGKNLLAINAKSGVIQTAAPL---DRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDS--------------YNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGL-------TIDYSTGEVTLRER--IDAK--NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDS------GPNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARY--SLKVTARDMGTPSLNTSTTIAVVLKDINDNAP------TFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKIT------YRIEE---ADREVFSILDIGDQGAILSVSGELKRQ-DHKVRVEISATDQGGLQGR----CVVNVFIDDVNSAPYFNDHPFSV-KIPEHSPI----GYPVITLKAEDHDRGDNARIVYSIDSSQ-FFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVIL 774 HSP 2 Score: 104.76 bits (260), Expect = 1.945e-22 Identity = 152/632 (24.05%), Postives = 285/632 (45.09%), Query Frame = 3
Query: 36 EAGKAFQNPRIRIDSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTII-LKKPLFDID-KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQDAL--SFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVV---NEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEM--KENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNED--LFWISE-------LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKN-HNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI-NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI 1868
E G+ + I DS NG+ Y +E S+ ++ I + + + L+ D E ++ L++ A D+G P L +S + + + DIND AP F K Y + E++ GS I+ + A+D + KI Y++ + + S + I G+ G I+ + L D K+ + + A D + V +FI DVN S N +P + ++I E++P + V + D D G N + ++ +DS + + + +DRE + + + D+ P L ++ ++V + D N+ FT S+Y+ +I E+ S L + ID D ++ LN S+ + S L L ++SG +R+ + LDRE QF++ V+ + ++ + +++ + D+NDN P + ++S+++ EN+ +G ++ D D G+N+ IS ++ G D LF I E ++IL + DYE N F + + + + +++ D NDN+ P+ D V+ ++ N+Q ++ + A D D ++ L Y L+ ++D I + +TG+I
Sbjct: 497 EVGRVYA---IDEDSGPNGIIKYSMEGSE----DFIIDEDSGLIKTTKLL---DRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADREVFSILDI-GDQGAILSVSGELKRQDHKVRVEISATDQGGLQGR---CVVNVFIDDVN--------------SAPYFNDHP-FSVKIPEHSPIGYPVITLKAEDHDRGDNARI------------VYSIDSSQFFRIDPSSGDISVSSDLDREDRAT-FSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESS--SSPSIQLFRLDRTSGTLRVSSKLDRE-----QFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTF-EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISF------------RIFGGADAKLFDIEEDAEQNGVVRIL-TRAEFDYEAKAN---KFFFELQASSGQLSSTVPVRIHVSDVNDNK-----PALKDFVILMNRFDNVQMARQIGFIPAFDPDQNAT--LEYFLE-ENDLIEAEKYTGKI 1052 HSP 3 Score: 100.138 bits (248), Expect = 4.979e-21 Identity = 124/488 (25.41%), Postives = 206/488 (42.21%), Query Frame = 3
Query: 240 DIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDID---KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIP-SYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP 1685
D QP L S+ L I++IDIND AP +A ++E++A+G + +V+AID +SG G I Y + +EDF ID +SG I K L D + + +L V A D + T + + + D+N++ P DK+ Y + I E P ++ + VD DE D K + + + +F + L+ L + + R+ + + I+ D G L+ ++ V + D N P F +S+ I E+ + +++ D D N+ ++++S + SSG+I + + LDRE R FS+ V + + + V++ DINDN PQ+ +IP Q+ D DIG N + L + P+ + LF + L+V +D E + I D G P I + + D NDN P
Sbjct: 453 DGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDF-----IIDEDSGLIKTTK-LLDRETTARYSLKVTARDMGTPSLNTS-TTIAVVLKDINDNAPTF----DKKE----------YNVTISEEMPRGSQIITLKAVDNDE----DQKITYRIEEADREVFSI-----LDIGDQGAILSVSGELKRQ--DHKVRVEISATDQGG--LQGRCVVNVFIDDVNSAP-YFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGD------NARIVYSIDSSQFFRIDPSSGDISVSSDLDRED--RATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDY-FLNESSSSPSIQ------LFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAP 890 HSP 4 Score: 83.5741 bits (205), Expect = 5.838e-16 Identity = 97/397 (24.43%), Postives = 174/397 (43.83%), Query Frame = 3
Query: 816 KNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVG-RMSFEMKEN-NIPSYELGQLIFDDKDIGENSRISISSLTTTCYGP-TEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKID--IHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIII 1973
+NLF LD T ++R+ +S+DRE + + + + P + ++ + V VLD + +F + +Y I E+ ++LS D D+ E + L N N L ++ SG I+ PLDRE + + ++ K S A V + V+D+NDN P + + + EN IP+ + + D+D G N ++ S +++ G T S E + +++ +D + N I I D P + + + +N++D ND+ P I + + N+ G ++ RV AID DS + + Y ++ D I ID +G I TK ++ +Y L + D G P N+S + +++
Sbjct: 210 QNLFTLD--------TMSGEIRLAKSMDREVLDKHI-LKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKN-----LLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKG--TPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAV-IATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGE----------VTLRERIDAK---NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEE----NVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFI-IDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVL 571 HSP 5 Score: 73.9442 bits (180), Expect = 5.594e-13 Identity = 72/274 (26.28%), Postives = 129/274 (47.08%), Query Frame = 3
Query: 1161 SFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSF-EMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDIEAGKYDL--FLQVTDNGNPMRNSSANLTI 1967
S +L +L SGEIR+ +DRE ++ + E D T ++ TV V VLD+ DN P + F E++E+ + + D D GEN I S + +G L ++ ++Q +D E + ++D+ D+G PK + + + ++D NDN P ++ S NV + +I I + + V+A D D ++ ++ Y + + ++ID TGE++L + I+A + ++ D P +S+ LTI
Sbjct: 209 SQNLFTLDTMSGEIRLAKSMDREVLDKHILKV-TAYERVDPT-ISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYS---------LGEGNGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAP--VFASDSYNVTILENITIPA--VIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTI 467
BLAST of Protocadherin vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 104.375 bits (259), Expect = 2.780e-22 Identity = 152/632 (24.05%), Postives = 285/632 (45.09%), Query Frame = 3
Query: 36 EAGKAFQNPRIRIDSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTII-LKKPLFDID-KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQDAL--SFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVV---NEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEM--KENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNED--LFWISE-------LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKN-HNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI-NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI 1868
E G+ + I DS NG+ Y +E S+ ++ I + + + L+ D E ++ L++ A D+G P L +S + + + DIND AP F K Y + E++ GS I+ + A+D + KI Y++ + + S + I G+ G I+ + L D K+ + + A D + V +FI DVN S N +P + ++I E++P + V + D D G N + ++ +DS + + + +DRE + + + D+ P L ++ ++V + D N+ FT S+Y+ +I E+ S L + ID D ++ LN S+ + S L L ++SG +R+ + LDRE QF++ V+ + ++ + +++ + D+NDN P + ++S+++ EN+ +G ++ D D G+N+ IS ++ G D LF I E ++IL + DYE N F + + + + +++ D NDN+ P+ D V+ ++ N+Q ++ + A D D ++ L Y L+ ++D I + +TG+I
Sbjct: 138 EVGRVYA---IDEDSGPNGIIKYSMEGSE----DFIIDEDSGLIKTTKLL---DRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ--KITYRIEEADREVFSILDI-GDQGAILSVSGELKRQDHKVRVEISATDQGGLQGR---CVVNVFIDDVN--------------SAPYFNDHP-FSVKIPEHSPIGYPVITLKAEDHDRGDNARI------------VYSIDSSQFFRIDPSSGDISVSSDLDREDRAT-FSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESS--SSPSIQLFRLDRTSGTLRVSSKLDRE-----QFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTF-EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISF------------RIFGGADAKLFDIEEDAEQNGVVRIL-TRAEFDYEAKAN---KFFFELQASSGQLSSTVPVRIHVSDVNDNK-----PALKDFVILMNRFDNVQMARQIGFIPAFDPDQNAT--LEYFLE-ENDLIEAEKYTGKI 693 HSP 2 Score: 99.7525 bits (247), Expect = 7.691e-21 Identity = 124/488 (25.41%), Postives = 206/488 (42.21%), Query Frame = 3
Query: 240 DIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDID---KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIP-SYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP 1685
D QP L S+ L I++IDIND AP +A ++E++A+G + +V+AID +SG G I Y + +EDF ID +SG I K L D + + +L V A D + T + + + D+N++ P DK+ Y + I E P ++ + VD DE D K + + + +F + L+ L + + R+ + + I+ D G L+ ++ V + D N P F +S+ I E+ + +++ D D N+ ++++S + SSG+I + + LDRE R FS+ V + + + V++ DINDN PQ+ +IP Q+ D DIG N + L + P+ + LF + L+V +D E + I D G P I + + D NDN P
Sbjct: 94 DGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDF-----IIDEDSGLIKTTK-LLDRETTARYSLKVTARDMGTPSLNTS-TTIAVVLKDINDNAPTF----DKKE----------YNVTISEEMPRGSQIITLKAVDNDE----DQKITYRIEEADREVFSI-----LDIGDQGAILSVSGELKRQ--DHKVRVEISATDQGG--LQGRCVVNVFIDDVNSAP-YFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGD------NARIVYSIDSSQFFRIDPSSGDISVSSDLDRED--RATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDY-FLNESSSSPSIQ------LFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAP 531 HSP 3 Score: 96.2857 bits (238), Expect = 8.423e-20 Identity = 133/582 (22.85%), Postives = 250/582 (42.96%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPF-----TGEISLTKDIEAGKYDLFLQ---VTDNGNPMRNSSANLTIIIYQQN 1985
I ++D+ND AP F + +Y + E++ + +VI V A D + G GK+ Y + + ++ID ++G + L++ ID +T + A D A+ + + I +ID+N+H P L+ + LE EN EV + +D+D G NG +K ++ ++ F +D L K T KL +DRE + + + +D G P L ++ + V + D N+ F + Y+++I E S I++ +D D + + ++ E F + + + + L R+ + V A D V+V + D+N + P + S ++ E++ Y + L +D D G+N+RI + S+ ++ + + SG+ + V +D E + + D P + I V + D NDN P++ +S IS +I GT +V AIDAD + + Y L S SI F +G + ++ ++ ++ + + D G P ++++ +T+ + N
Sbjct: 4 ITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGG--LTIDYSTGEVTLRE---RIDAKNSPITAVIRAKDGAQP-ALSSTVPLTINVIDINDHAPT------------LIAAQKMITLE--ENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSE----DFIIDEDSGLIKTT---KL-----LDRETTAR-YSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADR---EVFSILDIGDQGAILSVSGELKRQ-----DHKVRVEISATDQGGLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARI-VYSIDSSQFFRIDPSSGD-----------ISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQF---TSSSYAATISE-DIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVN 527 HSP 4 Score: 54.6842 bits (130), Expect = 3.894e-7 Identity = 57/230 (24.78%), Postives = 104/230 (45.22%), Query Frame = 3
Query: 1308 VSVVVLDINDNVPQYVG-RMSFEMKEN-NIPSYELGQLIFDDKDIGENSRISISSLTTTCYGP-TEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKID--IHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIII 1973
V + V+D+NDN P + + + EN IP+ + + D+D G N ++ S +++ G T S E + +++ +D + N I I D P + + + +N++D ND+ P I + + N+ G ++ RV AID DS + + Y ++ D I ID +G I TK ++ +Y L + D G P N+S + +++
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILENITIPAV-IATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGE----------VTLRERIDAK---NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEE----NVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFI-IDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVL 212
BLAST of Protocadherin vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 100.138 bits (248), Expect = 6.470e-21 Identity = 149/618 (24.11%), Postives = 254/618 (41.10%), Query Frame = 3
Query: 222 LQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLD--QNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNN----FNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQD---NTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPS-----------------YELGQLIF--DDKDIGENSRISISS--LTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQS--GTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGK-YDLFLQVTDNGNPMRNSSANLTII 1970
L++ A D G P S + + + I D+N+ +P+F +Y + E+ G I KV A D + G+ GKI + L N++ S S +SID +G + L K L D D T + A D + T++ I + DVN++ P V + I E+ P VS + D+D G+N +K + + K+ + + + ++ Y +D K N SI D+G P+L ++ L V+++D N F S+ EN + I + ++ + + +E + + N + + S+ Q G +R + LDRE Y ++ + D + + V + +LD ND+ P M N P+ L+F + D RI ++S +TT+ ++ +E W+S D G P+ + + +IVN+LDENDN P + I H +++S KL R+ A+DAD + RLTY + SID G I ++ I + Y L +Q TD+G P + +A ++
Sbjct: 688 LKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKS-SVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEG-FPMRVSVTNLTISVEDVNDNPPKCVVQHSR--------------ARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGCIFIHAPEY--------PLDYHKTPF-FNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSE---IGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQK-GTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVS------------------------ICDGGEPQLCSNVIVIVNVLDENDNSPTFTQA--------IHHYSVRSKFAGKLCRIFAVDADEGENARLTYNITEGDARFSIDN-NGNIIASEAIHGDESYALTVQATDHGTPGQQFAATRVVL 1243 HSP 2 Score: 84.7297 bits (208), Expect = 3.179e-16 Identity = 119/467 (25.48%), Postives = 208/467 (44.54%), Query Frame = 3
Query: 222 LQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFY------LDSRMRLNKNTYQYKLRIR-QSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVD--VLDQNEYPALFTRSNYSLSIIENKDNFSI-LSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFE-MKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVK--QSMDYEFIH 1583
L + CD G+PQLCS+ ++++++D ND +P F + V+ A + ++ A+D + G+ ++ Y + + + + SID N+G II + + + LTV+A D +F T VV+ + +P S S S + + Y + I + + V + D D GD L++ DS + ++T Q L + + + R ++ LN S+ +GQ ST+I+QV + + ++ A +++ S + +++ S + L FN F S ++ ME + SSG + + PLD E + R + VV Q N K SFAT SV + D NDN P +VG +F + E++ L + DKD GEN ++ S +SGNE+ + + K +V+ + +D E H
Sbjct: 1124 LWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSVRSKFA--GKLCRIFAVDADEGENARLTYNITEGD----ARFSID-NNGNIIASEAIHGDESYALTVQATDHGTPGQQFAATRVVL-TANSAGQKPRKSKNSPPEISGKKSD----YVIPISDADQVGLTVGKLEASDAD----GD------------ELWWSISSGDPDSVFDVRQDTGQLLLAKKVELLKRGELR--LNISVT---DGQAWDHSTVIIQVSRQISQRPKFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLVFNLF---SVDDVAMED--KIRVEPSSGNVIVMEPLDYEAARRIRA---VVQVQQANMK--SFATFSVNINDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSI-----------VSGNEESLFKIDAKSGEVRLAKPLDPELQH 1536 HSP 3 Score: 71.633 bits (174), Expect = 2.584e-12 Identity = 80/309 (25.89%), Postives = 137/309 (44.34%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FD-IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQ-TTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDA 1109
D E + F L ++A D + +++ +ID ND AP F Y+ V E ++G + A GD + I +K D TSFV+++ +G + L KPL F+ + L LTV A DS + + V I ++D N++ P Y ++ EN+ +V + +D D G V +++ ++ + L + N + I QSID EK+ N + +D G+P L+S +L++ V D+N++ F N + + E + +L F+V D D
Sbjct: 3075 DSEILGFFNLTVVASD---GEFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRA---SGGDQNETIEYYLKPSDV-TSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETE-AQVEISVMDENDNAPKFEKEK--------------YVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVL-----ISQSIDYEKIKK-YNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLDG 3355 HSP 4 Score: 71.633 bits (174), Expect = 3.009e-12 Identity = 96/419 (22.91%), Postives = 180/419 (42.96%), Query Frame = 3
Query: 222 LQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-VSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFI--IDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDR---EKVSN-PLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFD-DKDIGENSRI 1454
++IA G + + + + I+I+D ND AP F AK + G V++KV A D++ G+ GKI+YK F++ + I+ N+G I L + + TV A D S+ +++ + + I + + + + + +P +E+ E+ P V+ + D+D G NG ++ I S L + ++ + + + EK+ + ++ D G P+ S +++ + D N + F +Y L I EN+ + F V D N + S N E + S+ +G +++ LDRE + F+I +E S +++ V D+NDN P+ V + S ++P + D+DIG+NS++
Sbjct: 460 FKVIASLHGINEKLAEKDVSIEILDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYK------FTSELPLEINANTGEITLVEVPKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENKHSPVFSSFP-EIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHD-------IAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDI-FKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEG--FPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKL 861 HSP 5 Score: 70.0922 bits (170), Expect = 8.724e-12 Identity = 74/310 (23.87%), Postives = 134/310 (43.23%), Query Frame = 3
Query: 1092 VIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMK--ENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSIS---IDPFT----GEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
++ +DA F+E ++F L + +G + + PLD E F + + +F AT+ V V+D NDN P + + ++ MK E+ YEL D E + T + +G IL + + +D+E + K+ + D G P + + ++++DENDN P++ + V N +SG K+ V+A+D DS ++YEL+ ++ + + PF G++ +++ I+ KY+L + D G P S A L I + +N
Sbjct: 3037 IVAEDA-DFDEIKFRMVDDFG----GLFQIDDINGVVTVVKPLDSE-----ILGFFNLTVVASDGEFEDKATILVTVIDQNDNAPTF-EKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTG-----------ILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKF----EKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDEN 3320 HSP 6 Score: 63.929 bits (154), Expect = 6.105e-10 Identity = 85/306 (27.78%), Postives = 140/306 (45.75%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDI--NDEAPKF--VAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKII-----YKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT-----LTVEAHDSA----EHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLD--SRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSI 1052
DY P F L + D G P L +S L ++++DI N A +F VAK + V E+ +G+ ++ + A +E+GD K+ Y++I + + SID GT+ + +D+ T +TVEA DS + + D HV I I+D N+HRP + P+Y + EN+P N V+ K E + D L+ + D S R++ + + +DREK S ++ D G+P L S +I+ V+VLD+N+ FT++ + S+
Sbjct: 891 DYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEAS--VYENSEIGTEVIMIEA--KETGDEQKVKAENLEYRIIGGDGW--PHFSID-QKGTV---RTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRP--------------VAKKPMYIASVAENSPANV------VIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSE-HELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSV 1165 HSP 7 Score: 59.6918 bits (143), Expect = 1.192e-8 Identity = 127/595 (21.34%), Postives = 239/595 (40.17%), Query Frame = 3
Query: 276 LVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENN--PENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDS-------RMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQ---PLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYE-----LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL-KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
+ +DI D+ND AP F + ED AVG+ + A+DR+ G+I + L++ + ++ NSG + + L ID L A D N+ +T I + DVN+ P + L + PI I +++ P N FI +EG +F++DS R + +N QY+L++ + S + ++ + P T+IL +N SL + N ++F + D D N F +N N +++ + +D EK+ + +F + QDN++ ++VV+ ++NDN P+ + ++ + N+P+ E + +++ +D D E I +G LF I ++ ++ V + +D E + + + D F +K +I+V ++D+NDN P + + V+ I G +L RA D + + Y LK + ++++ TG ++L K ++ L + D+G P + A + I + +N
Sbjct: 2698 VTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEE----NPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEGGFNTDLPFT---IVVSDVNDSPPQFE-KEEFNIDLHLPSTSPILHFSIKDDDLSPNNVSQFFIP-KGNEEG-----------------VFWIDSNNDLLLKRPEIVENKMQYQLKVTAFDGVFETSTKVKINLKSSKDSDIRCPEANKTVILA-----ENSKKGTVVLGESSL-LGPN------VTFKLSDNDG---NVFVVNFRNGIV--------------KVKESDQIDYEKNQQLEFHRLTI---QDNSEVCK-ELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDE-----IKFRMVDDFG---------GLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDGEF---EDKATILVTVIDQNDNAPTFEKSTYSMKVMESESI----GYELAHFRASGGD--QNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDEN 3210 HSP 8 Score: 57.7658 bits (138), Expect = 4.922e-8 Identity = 62/264 (23.48%), Postives = 116/264 (43.94%), Query Frame = 3
Query: 906 KVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLN-SSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMS-FEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW 1691
K L+ +I D+ P +T ++V++ ++ F+ S+Y S++E+ D +++ + Q +E + +SF S+ +S+G+I + + LDRE+ +++ +I A + TV+V + D+NDN P + G F + E+ + D+D + RI S + Y NE+ W L V +D E I + K+ DEG +I+V+ D ND+ P++
Sbjct: 2569 KAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVI--GRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTI----RADAAGGVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPY-----FDLNENSGW------LTVASQLDREKIDHYKLIARATDEGGFNTDLPFTIVVS--DVNDSPPQF 2813 HSP 9 Score: 55.4546 bits (132), Expect = 2.488e-7 Identity = 67/247 (27.13%), Postives = 114/247 (46.15%), Query Frame = 3
Query: 966 KSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQ-----YVGRMSFEMKENNIPSYELGQLIFDDKDIGENS-RISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP 1685
K+TI+ V V+DQN+ F +S YS+ ++E++ + + F D E++L S+ + SF +L +G + + PLD E + + VV + + A V + V+D NDN P+ YVG++ E ++ + L D + G S + I S TTT T L F I+ + + QS+DYE I + + D G P ++ + +++ DEND+ P
Sbjct: 3096 KATIL--VTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQNETIEYYLKPSD---VTSF--VNLNAQTGILTLAKPLDFETLSALKLT--VVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVK-ENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTT---DTPVLP-----FAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAP 3324 HSP 10 Score: 54.6842 bits (130), Expect = 3.958e-7 Identity = 88/388 (22.68%), Postives = 149/388 (38.40%), Query Frame = 3
Query: 243 IGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL---FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLN----GYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILS-------FAVIDQDALSFNEFHLNSSNNFNMESF---HLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY 1352
+ Q + S ++I D ND +P FV V E V V+ V A D++ G+ G + Y ++ + S ID SG + L KPL + L + A DSA ++ K + + I +N P + K T L + G P+ L + ++++ + C L +L T+ KL+ R+S++ + + + Q + K + ++ N++ +F R Y +I EN S+LS + ID+D S N + M S + S+ Q SG IR D EK Y F + + Q + + + V V+D ND P++
Sbjct: 1442 VQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNE--ESLFKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAANSLKDEMS----LHIRNSNEAPETAKFDRKVYQTTLYDSTRPGTPVLVLNALHHGTVSYKL--------------EPNCTFFEVHTLSGAVHL--------ATWLTKLKHRKSVECTAI-------VESTEGQQDIAK----VIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGS------NGLVGYRMLSPKDEQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPRF 1784
BLAST of Protocadherin vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 93.2041 bits (230), Expect = 7.442e-19 Identity = 141/635 (22.20%), Postives = 273/635 (42.99%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFST-SFVSIDGNSGTIILKKPL-FDI-DKLTLTVEAHDSAEHNSKFD-WTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQ-----YKLRIRQSIDREKVSNPLN----FSINCQDNGQPLLKSTIILQVDV--LDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLN-----SSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSF-EMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS---ELKILQVKQSMDYEFIH----NCKIDIHFHDEGFPKNH--NKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGK---YDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQSI 2000
D E + ++ L++I GQ Q+ + ++ + + ++ND P F + + V E+L VGS + V A D + + + Y L+ + T + +ID +GTI L PL F++ + TLT++A D + FD +T++ IF+ D+N++ P S P+Y + +P F G +I+ L D+R L + Q +++ KV P ++ DNG P +++ + V + + + P F ++ + ++EN S + + + EFH +S F+++ F G + + P+DRE+ ++F + + NE + K V+VLD NDN+P + + +K++ ++GQ++ D+D GEN R+S LSGN DL ++ + +Q+ + D + +I + D G P K+ + + + + + P ++ P +V+ + + GT L ++RA + + ++ L Y LK + ID TGE++L ++ ++L V+D R++ L I++ + F +
Sbjct: 1889 DREILERYSLKVIGTGSGQ-QIGT--RVDVRVNNLNDNVPSF-PMSKPRRVPENLRVGSYVATVGAKDVD--NLAPLRYFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGS-----FDTFTNLTIFVSDINDNAPTFS--------------KPLYQTTV---SPATF-------------SPGQPFAKIEAHDL-------DARGALTYSLGQGSSSIFRVAPESGALFMKVLPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPG-FEKAEFRFEVMEN----SKIGLQIGNLSGEESREFHYRIQDPEASKIFSIDKF---------GRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQ--CKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSY-----------RILSGN-DLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSV----GTVLQKIRASNRLGMRNDGLLYSLKEHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG--RSAVVPLKIVVEPVDEFAPV 2441 HSP 2 Score: 89.3521 bits (220), Expect = 1.159e-17 Identity = 128/596 (21.48%), Postives = 250/596 (41.95%), Query Frame = 3
Query: 234 ACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYP-IYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKEN---NIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPE----WIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
A D G P L + ++V D++D + P+F + + ED +G+ ++KV A + + G+ +I Y L +N+D +++D SGT+ ++K FD +K + NS+ + + I + DVN++ P YP Y L + E + ++ D D G G+V I L + N ++ ++ + R + + ++ +D G +++ + + V+D++ F+RS Y + E+ + A+ A+S ++ + ++ + H S+ + +G+I + LD + ++ + +A + ++ V + + D NDN PQ+ + ++E+ + P Y + D K GE R SI S ++ +G L +DYE N K+ + D G P + +++ +++LD NDN PE W L+N T + +V A D DS+ + ++ Y + + ID G + + I+ D+ + D G P R+S+A+ I + N
Sbjct: 512 AEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL-QNQD---EHLTVDTMSGTVCIQK-TFDFEKQKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIF---------------YPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHI-----------LSESSSFSINPVTGEVFAQKPLARGR----FHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDI----LPGIAIGSVGAMSKVKYSI-----YSGDQDHNFSIDEDTGKIYVTRYLDAD----VHDTVLLNIQATLPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGE-VRYSIISSHPGSSIEIDQFTGQ-----------LSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENS--------PPKTIVGKVVARDKDSLENGQIVYRITNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVN 1039 HSP 3 Score: 83.1889 bits (204), Expect = 7.476e-16 Identity = 135/615 (21.95%), Postives = 248/615 (40.33%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRL----------NKNTYQYKLRIRQSIDREKVS-NPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVV--VLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTK----LTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D EF K+ L + A D G+P + I+IID ND AP F YT V ++++GS ++ V A D + G+ +I Y + K S S +I SG I L + V A D H S + V+ I + + L+ P+ + + E+N + + G + ++ + Y D+++RL + Y L + +DRE S + L F + + +GQ +++ +L + D N+ + S +S+ N+ + D D N +++ L S+ + +G I + N +D +F + A+D + VV +LD PQ+ + E+ E+ L +++ ++ G + RI S + + +SG + ++++ D+E + + + + + + ISI + D NDN P + YP N H+ ++ G K L V A D DS + ++Y + ++ S SI+P TGE+ K + G++ L + D G +SAN+ I + ++
Sbjct: 192 DREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAIS-QSGVITTTASLLPASTHDVIVVASD---HGSPSLSSSAVVTITVLGS----------------TLSSPPLDIIWLVESNSAHL---------MENSTLGSIVARVSIAQQ-----YRDTKLRLIGSSALCPQQTDQAHVYLLLLCGILDRETASEHHLKFLL--EKDGQIIIEHPQLLTIG--DINDNAPQWHSSQIHISL--NRTQGGSRTLTAKDPD------LGQNGWIRYSVLDTELVSIDKETGRIFVPNTIDCNIGSEIKFRV----RAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDEHLTVDTMSGT-----------VCIQKTFDFEKQKSYQTTVIATNANSETSTSLISI--RLKDVNDNWPIF-YP-------NEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSSFSINPVTGEVFAQKPLARGRFHLVVSAKDGGGQSSENSANIHITVIDKD 735 HSP 4 Score: 70.4774 bits (171), Expect = 5.874e-12 Identity = 106/418 (25.36%), Postives = 177/418 (42.34%), Query Frame = 3
Query: 213 KFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDI-DKLTLTVEAH-DSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVI-DQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRI 1454
+F L + A D G +S + I +ID + + P+F Y ED+ G I V A+ + IY ++ +F SID ++G I + + L D+ D + L ++A S E N T VVIFI D N++ P S + + I E+ + + DKD+ KNG+V+ I ++ + S + +++ T Q L +D E N + D G P S + L + VLD N+ F +S Y++ ++EN +I+ V D+D+L + +N E F + + G + +DRE SI V E + +S A+ + VLD+NDN P + + + S +G ++ D D G N +
Sbjct: 706 RFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAMSK----VKYSIYSGDQDHNF-----SIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGESNQ----TQVVIFIEDHNDNPPQFSSS--------------LVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISS-------HPGSSIEIDQFTGQ--LSTGSLLDYEATRN-YKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITN--GSEYF---GIDEKLGNVYTKRSIDREVISHVDISI--VAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSV 1079 HSP 5 Score: 67.3958 bits (163), Expect = 5.908e-11 Identity = 80/340 (23.53%), Postives = 155/340 (45.59%), Query Frame = 3
Query: 999 DQNEYPALFTRSNYSLSIIEN---KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSS---LTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLT----RVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAG---KYDLFLQVTDNGNPMRNSSANLTIII 1973
D N+ P F+ S +SI E+ + F ++ + D+ N +++ S H S + Q +G++ G+ LD E + Y+ + + +S T+ + VLD+NDN P++ + E+ EN+ P +G+++ DKD EN +I +++ + F I E L + K+S+D E I + I I D+G P + S +++LD NDN P + ++I+ I + +G+ L+ + A+D D + + Y + + S+ + G++ L + + A L + V+D G P ++ ++ + I
Sbjct: 829 DHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKK--------NGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGI--PPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQI------------VYRITNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPP---------SCLSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQ-SSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHVPVRI 1136 HSP 6 Score: 65.4698 bits (158), Expect = 2.344e-10 Identity = 57/211 (27.01%), Postives = 97/211 (45.97%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIF-----ENNPENFEVSFINVVDKDEGKNGDV--KCQIQTT 806
DYE + L++ A D+G P S+ L I ++D+ND AP+F YT V E+ +++ KV A D++S + G+I+Y++ + + ID G + K+ ID+ + +HV I I+ + P S + R S +N P L I +P + + I +D D+G NG V + Q+Q++
Sbjct: 901 DYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSE----YFGIDEKLGNVYTKR---SIDREVI----------------SHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQSS 1088 HSP 7 Score: 53.9138 bits (128), Expect = 6.542e-7 Identity = 73/290 (25.17%), Postives = 122/290 (42.07%), Query Frame = 3
Query: 1185 QSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISIS-SLTTTCYGPTEK--------LSGN-EDLFWISELKI-------LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPF----TGEISLTKD-IEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNM 1988
+ SGEI LD EK ++ V E+ + + V V D NDN P + ++ +I E +++ S +L T G K L GN ++F ++ K+ L V +D EF ++ I D G P ++ + I+D NDN P + S NI G+ L V+A DAD ++R++Y++K K + S F +G I+ T + A +D+ + +D+G+P +SSA +TI + +
Sbjct: 73 ERSGEISTIAHLDYEKRSKFDIVAVKVEESGETID------ILVEVDDENDNAPSFADQVV-------------------KLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVF----SRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIK-KTSAPSNSNFAISQSGVITTTASLLPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTL 332
BLAST of Protocadherin vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 82.4185 bits (202), Expect = 1.546e-15 Identity = 127/557 (22.80%), Postives = 234/557 (42.01%), Query Frame = 3
Query: 276 LVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT-------LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRT---STQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSI---DREKVSNPLNFSINCQDNGQPLL--------KSTIILQVDVLDQN--EYPALFTRSNYSLSIIEN---KDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESF----HLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQL-IFD-DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-----SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKN-HNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA 1826
L I I D+ND P F YT V+ED+ + ILKV A+D+++GD +I Y + N +FS NS I K D D+L V A D E S + ++ + N + + + + T + G P+ ++ + + + SF++ KNG ++T+ + NLF +D L +++R + D + NP+N ++ QD+G + +T+++ ++ ++ N E+P S+ + I+E D +I+ D D+ + + + L + + + ++F LT S + DRE PR ++ + + F SV V+DINDN PQ+ R S+E + + + +F D D N+ I+ S T G E+ + D F + E+ +++ +FI N D D G P+ + + +N+LD+ P+W + + N++ + R RA+ + ++ + Y+L A
Sbjct: 628 LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYS-VDNHNFSI-------NSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVS-LSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMD-------KNG------RSTQKM-NLFSIDEHTGL--------VKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIA-KIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVV-----FDRETRPREDVTVKATDRG--DRPLIGFCQFSVEVVDINDNSPQFE-RPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAG--EEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFIFNVIAD----DNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDE-NVELNKVILRCRAVSSGDSRNSDVIYKLTA 1137 HSP 2 Score: 77.7962 bits (190), Expect = 3.724e-14 Identity = 136/571 (23.82%), Postives = 232/571 (40.63%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQ-------KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGS--VILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDI-DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSN--PLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFN---------EFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI--------SELKILQVKQSMDYEFI---HNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRL 1808
D E I ++L + A D L + K+ I I D+ND AP F + Y V+E G + +K H +D+ S + Y LI F + +SGTI +K+PL F+ D+ L + A D HN+ T+V I I DVN++ P T + P + + + E S +V + EG+ D R+ K Y + + +++DR+ + NF + D+ L +QV+V D N+ +F + I EN++ +D A F+ E+ + + N ES + + Q++G+I LDRE S +F I V + FA V++ V D+NDN P + + +E + F D E ++ ++ T +LS D F++ S + +L+VKQ +DYE + + I D ++ + ++ V ++D ND+ P I+ ++ V ++ GT + R A D D+ + R
Sbjct: 1287 DREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHS----NLRYHLIGAGGGRIPF-GVRTDSGTIFVKEPLDFEASDQYHLVLIASD-GRHNAT---TNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSS-RIVYRLEGQGAD------------------EVFRIGK--YSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFGY-IEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGES--VFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAP-FFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVF---------TYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDG---RHDAEAAVHVALVDRNDHAPH-IHGATEHRVRE----DVPRGTSIGRYTATDRDAGDTARF 1806 HSP 3 Score: 77.0258 bits (188), Expect = 5.931e-14 Identity = 157/680 (23.09%), Postives = 276/680 (40.59%), Query Frame = 3
Query: 75 DSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKL----IKNEDFSTS---FVSIDGNSGTIILKKPL-FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRL-----NKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSI---------IENKDNFSILSFAVIDQDALSF-NEFH---LNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEA-----------QDNTKFTSFATVSVVVLDINDNVP-----QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKIS-IIVNILDENDNEPEW---IYPSS-LDNVVNISHINIQSGTKLTRVRAIDADS-VSSNRLTYELKAKH--DSISIDPFTGEISLTK----DIEAG--KYDLFLQ-VTDNGNPM 1940
DS+ NG Y L +Q R F+++R +L+ D E P+ + + A D G L + ++++DIND +P+F +Y V AVG+ ++ V A D ++ +I Y L E+ F ++ SG I L KP+ K V A D+ + V + ++D P D + + + EN N + V + +N DV ++ + N +S+ R N N + ++ I + +D E+V+N ++ D + ST V+V D N+ FT ++ +I +E + I++ ID D+ NE H + +N + F + LT GEI DREK Y ++ + + +DN K V +V+ D+NDN P +Y+GR +KE+ +++ + D D N R + G F + ++ + VK+ +D+E + + D HN + + ++I D NDN P++ Y ++ ++ V+I + L V A DAD S+R+ Y L+ + + I ++G I L K D AG ++ +Q + D+GN +
Sbjct: 898 DSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPG-----------ITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGN--KAESKFRQFNKFENGNEW-VEVVIMEGLDYEQVNN-YTLTLTATDM-TSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELT---GEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVK------VQIVINDVNDNAPSFEEQKYIGR----VKESEGEGHDVITIKAHDLDKHSNLRYHLIG-----------AGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASD----GRHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKV-------LFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGL 1526
BLAST of Protocadherin vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 143.28 bits (360), Expect = 4.626e-34 Identity = 157/625 (25.12%), Postives = 258/625 (41.28%), Query Frame = 3
Query: 210 PKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRT---STQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNME-------------SFHLSSLTQ------SSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVV--VLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS-----ISIDPFTGEIS---LTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
P +L + A D G + + + + IID P F Y V+ED+ G+V+ V A + + Y + + + SI+ NSG I + KPL K + + + + T V I + DVN++ P + + S +L G P+Y DKD G +G V + + K LF +D+R L + Q +D E S + D G P L + + + VDV D N+ P +F + YS+++ E++ I+ + N L++ NN + S S ++Q +SG I + PLDRE RYQ ++ A DN + A V+ VLD NDN P++ + F ++EN +G + D D+GEN+ I S L ++G + ++ +D E + + D+G P ++ + +++ D NDN PE P ++VV++ GT++ RVRA+D D + +TY + DS SIDP +G I + E Y L + +D GNP R + L + + N
Sbjct: 791 PMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGD--PDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAEL--GAPLYAAHAH---------------DKDSGSSGQVTYSL-VKESGKGLFAIDAR--------SGHLILSQHLDYES-SQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRS---------INAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVL----ATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGE-----------ISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQ--EDVVSVRE-EQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLN 1359 HSP 2 Score: 112.079 bits (279), Expect = 1.575e-24 Identity = 127/505 (25.15%), Postives = 215/505 (42.57%), Query Frame = 3
Query: 219 VLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI---QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNM----ESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVV--VLDINDNVPQYVGRMS--FEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW 1691
VL I +G+P + ++ I++ D+ND AP+F A V E +G+ + HA D++SG G++ Y L+K + +ID SG +IL + L + TL V A D + + T +++ + DVN++ P D+ Y + + E+ N ++ +N D D G N + +I + ++ D + +R +DRE + ++ DNG P + + V VLD N+ F +S Y I EN S++ V+ L E N++ +++ SF + +T GEI PLDRE Y V EA+D A V V V D+NDN P+ ++E P E+ ++ D+D G+N+ I+ S + + S LF I +++ + +D+E ++ + D G P + V +LD NDN P +
Sbjct: 898 VLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVK--ESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLT-ILVDVQDVNDNPPVFE--KDE------------YSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRE-TRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVV--GVVTASDLDLGE---NAAIRYSLLPINSSFQVHPVT---GEISTREPLDRELRELYDL----VVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKG-------RDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTF 1365 HSP 3 Score: 109.768 bits (273), Expect = 7.321e-24 Identity = 153/640 (23.91%), Postives = 281/640 (43.91%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQ---PQLCSSQKLVIDIIDINDEAPKFVAKNYTK------VVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLF----DIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRM----------RLNKNTYQYKLRIRQSIDREKVSNPL------NFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEG-FPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSIS----IDPFTGEISLTKDI--EAGKYDLFLQVT--DNGNPMRNSSANLTIII 1973
D+E + +++L + A D +L +S + + I+D ND AP FV+ N + + + +G V+ + A+D +SGD G++ Y++ I+ +G I L K L D++K L + A D + K ++ + + +N+ P + L +Y I EN P V + +N ++ +I + +LF++D + R ++ +Y + +R + + +S+ + SI NGQ +TI + V ++ N P S Y LS+ EN + I + D D L ++ N N F+++S SSGE+ PLDRE+ RY I + Q ++ +++ V D NDN P++ + + + ++E+ + Q+ D D+G N+R+ S T + + G L I+ + L + Y F+ + D G + + + +N+LD NDN P + + V + IQ G L +V+A+DAD ++ + Y L A++ ++S I+P TG +S ++ + E+GK L L+V D GNP ++S + ++I
Sbjct: 1558 DFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGN--GEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPP------------RFLQA--VYRATILENVPSGSFVLQVTAKSLHGAENANLSYEI-PAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNS-PEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDS--------SSGELS-ARPLDREQHSRYTLQIQASDRGQPKSR-QGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQW--QFAIDGQSGL--ITTVGKLDRELQASYNFM------VLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPAL----IQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKL-LHLEVVARDKGNPPQSSLGLIELLI 2154 HSP 4 Score: 100.138 bits (248), Expect = 8.016e-21 Identity = 145/624 (23.24%), Postives = 263/624 (42.15%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKL-----------IKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENK-DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQL--IFDDKDIGENS--------RI--SISSLTTTCYGPT---EKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKN--HNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL--------KAKHDSISI---DPFTGEISLTK--DIEA-GKYDLFLQVTD 1925
DYE + L + A D G P L ++ +++D+ D+ND P F Y+ V E ++ + I++V+A D ++G+ +I Y++ I + D S F I NSG I L+ PL D+ LTV A D+ + T V++ ++D N++ P Y I EN V + D D G+N ++ +L ++S +++ T + + R+ +DRE + + + +D G P+ + + +++ V D N+ P + +S+ E + ++ +D+D + + + L S+ +SG IR LD E+ Y+ + + N + + V VLD+NDN P + + F ++E+ + +G + I D+ NS R+ +++ LT ++ SGN L V + +D E +++I D N + I++ + + D NDN PEW V + + GT + A DAD+ ++ L Y L +++ ++S+ D TG +SL D EA +Y L +Q D
Sbjct: 995 DYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHF-GIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGT-PAAHAKTRVIVRVLDANDNDPKFQKSK--------------YEFRIEENLRRGSVVGVVTASDLDLGENAAIRY---------SLLPINSSFQVHPVTGE--ISTREPLDRE-LRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGG--NPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGN-----------LVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPV----GTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALD 1573 HSP 5 Score: 90.1225 bits (222), Expect = 8.846e-18 Identity = 143/636 (22.48%), Postives = 256/636 (40.25%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQ-KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPAL-FTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFN-EFHLNSSNNFNMESFHLSSLTQSSGEIRIGNP---------------LDREKSPRY-----------------------------------QFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK---ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH----DSISI---DPFTGEISLTKDIE 1889
D E ++ LQ+ A D GQP+ + I + D ND AP+F YT VQED +G+ ++++ A+D + G +++Y L + +IDG SG I + +D+ V A D + + V I ++D+N++RP + YP Y ++ + + +D D G N ++ + + ++ R+N +T L QS+ E L+ + +D G P S ++++ + + + P L F Y + + EN + + +L + D +F + N + S L SL SGEIR+ P L R ++ Y + + +V D S+A + + + D NDN P++ + + E N + Q+ D D G N+R+ + GN D ++ E I++ +D E K+ I DEG P+ +I V I+D NDN+P +P +N+V +S + G +T + A D D+ + LTY L A+ +++SI D ++G++ L + ++
Sbjct: 1910 DREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQ---FAIDGQSGLITT---VGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRP-------------IFERYP-YIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAEN-----SAVSAKFRINPST--GALSASQSLASES-GKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILS--LDSL---SGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRY-----------HIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQP--TFPP--NNLVTVSEAT-ELGAVITSISANDVDTYPA--LTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLD 2494 HSP 6 Score: 89.7373 bits (221), Expect = 1.112e-17 Identity = 152/619 (24.56%), Postives = 260/619 (42.00%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDIDKL-TLTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISV--GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQD-----ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYVGRMSF---EMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI------LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWI---YPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK-DIEAGK----YDLFLQVTDNGNPMRNSSA 1955
D E P + L + A D G P L + I I D+ND P F Y V E+ VG+ +L+V+A D ++ + G + Y + + + ID +G I + K L F+ +L L V A D E + T V I + DVN+++P I+V SD + + P F+ + + + + NV G +G F L +R + Y + + +DRE VSN S+ D G P L ++ + + + D N+ P F + Y +++E D S+L D+D AL+++ L + + + F + T G I + +D E P Q ++ A+D +S ATV V + D+NDN P + SF + EN + ++ D D G N+ ++ + E ++E ++ + + +D+E + + + D G I + + D NDN P + Y SL S + S T + V A D D + +++Y + A +++ ID TGEI + + D+ + + + L + TD GN N+ A
Sbjct: 245 DRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQ--PLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGH--------------FALTTR-----DNSIYLVIVHLPLDREIVSN-YTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYS---LAETPETHAQWFQIDPQT---GLITTRSHIDCETEPVPQLTVV----ARDGGVPPLSSTATVLVTIHDVNDNEPIF--DQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTI--------------GEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKM--QLTDVNDNRPVFYPREYKVSLRESPKAS--SQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADA 811 HSP 7 Score: 74.7146 bits (182), Expect = 3.967e-13 Identity = 139/571 (24.34%), Postives = 241/571 (42.21%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDF---STSFVSIDGNSGTIILKKPL-FDIDK-LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFL------EIFENNPENFEVSFINVVDKD-EGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDAL--SFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVN----EAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPS--YELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL--KILQVKQSMDYE-FIHNCKIDIHFHDEGFPKNHNKISII------VNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL 1820
D E + L++IA D G PQ+ + + + I+D+ND P F N V E +G+VI + A D ++ + + Y+L + S ++D SG ++LK+ L +++ + L V A D+A H ++ + + VN+ N V L P YF EI E+ +F++ +N D D EG N V I+ + ++ + + +N + Q + S I +D G+P LKS+ +L+V D + F ++ Y I E S++ + QDAL S N + F L QS + + PLDRE++ Y+ + + + + +S +V + +LD NDN P + +E + + + Y + QL D D EN+ S Y T SGN++ + +L +L V +DY+ + ++ I D +H++ + + + DENDNEP++ L V+ N G+ + R A D D +L Y +
Sbjct: 2387 DREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLV-TVSEATELGAVITSISANDVDT--YPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAA-HEAR------TVLTVRVNDENDNAPV--------FLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAV---------SSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVV--LQLGQDALDQSLAIIAGNEESAFE--------LLQSKAIVLV-KPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDAD-QENTPNS-----EVVYDIT---SGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACD-----SHHQRPLCSLQPFRLELHDENDNEPKF----PLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSI 2901 HSP 8 Score: 52.7582 bits (125), Expect = 2.307e-6 Identity = 51/209 (24.40%), Postives = 87/209 (41.63%), Query Frame = 3
Query: 195 DYEFIPK-FVLQLIACDIG-QPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKL--IKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVG----SDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI 797
DY+ K + L + ACD Q LCS Q +++ D ND PKF Y + E+ VGS + + HA D + G FG++ Y + +++ S +D SG ++ +FD E ++D + D+ + +++V S + Q + L P+ + V + D D G +G V Q+
Sbjct: 2819 DYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESG-LVTSAFVFDY-------------EQRQRYDME---LLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQL 3010
BLAST of Protocadherin vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0343249) HSP 1 Score: 143.28 bits (360), Expect = 4.626e-34 Identity = 157/625 (25.12%), Postives = 258/625 (41.28%), Query Frame = 3
Query: 210 PKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRT---STQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNME-------------SFHLSSLTQ------SSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVV--VLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS-----ISIDPFTGEIS---LTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
P +L + A D G + + + + IID P F Y V+ED+ G+V+ V A + + Y + + + SI+ NSG I + KPL K + + + + T V I + DVN++ P + + S +L G P+Y DKD G +G V + + K LF +D+R L + Q +D E S + D G P L + + + VDV D N+ P +F + YS+++ E++ I+ + N L++ NN + S S ++Q +SG I + PLDRE RYQ ++ A DN + A V+ VLD NDN P++ + F ++EN +G + D D+GEN+ I S L ++G + ++ +D E + + D+G P ++ + +++ D NDN PE P ++VV++ GT++ RVRA+D D + +TY + DS SIDP +G I + E Y L + +D GNP R + L + + N
Sbjct: 791 PMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGD--PDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAEL--GAPLYAAHAH---------------DKDSGSSGQVTYSL-VKESGKGLFAIDAR--------SGHLILSQHLDYES-SQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRS---------INAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVL----ATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGE-----------ISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQ--EDVVSVRE-EQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLN 1359 HSP 2 Score: 112.079 bits (279), Expect = 1.575e-24 Identity = 127/505 (25.15%), Postives = 215/505 (42.57%), Query Frame = 3
Query: 219 VLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI---QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNM----ESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVV--VLDINDNVPQYVGRMS--FEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW 1691
VL I +G+P + ++ I++ D+ND AP+F A V E +G+ + HA D++SG G++ Y L+K + +ID SG +IL + L + TL V A D + + T +++ + DVN++ P D+ Y + + E+ N ++ +N D D G N + +I + ++ D + +R +DRE + ++ DNG P + + V VLD N+ F +S Y I EN S++ V+ L E N++ +++ SF + +T GEI PLDRE Y V EA+D A V V V D+NDN P+ ++E P E+ ++ D+D G+N+ I+ S + + S LF I +++ + +D+E ++ + D G P + V +LD NDN P +
Sbjct: 898 VLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVK--ESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLT-ILVDVQDVNDNPPVFE--KDE------------YSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRE-TRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVV--GVVTASDLDLGE---NAAIRYSLLPINSSFQVHPVT---GEISTREPLDRELRELYDL----VVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKG-------RDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTF 1365 HSP 3 Score: 109.768 bits (273), Expect = 7.321e-24 Identity = 153/640 (23.91%), Postives = 281/640 (43.91%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQ---PQLCSSQKLVIDIIDINDEAPKFVAKNYTK------VVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLF----DIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRM----------RLNKNTYQYKLRIRQSIDREKVSNPL------NFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEG-FPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSIS----IDPFTGEISLTKDI--EAGKYDLFLQVT--DNGNPMRNSSANLTIII 1973
D+E + +++L + A D +L +S + + I+D ND AP FV+ N + + + +G V+ + A+D +SGD G++ Y++ I+ +G I L K L D++K L + A D + K ++ + + +N+ P + L +Y I EN P V + +N ++ +I + +LF++D + R ++ +Y + +R + + +S+ + SI NGQ +TI + V ++ N P S Y LS+ EN + I + D D L ++ N N F+++S SSGE+ PLDRE+ RY I + Q ++ +++ V D NDN P++ + + + ++E+ + Q+ D D+G N+R+ S T + + G L I+ + L + Y F+ + D G + + + +N+LD NDN P + + V + IQ G L +V+A+DAD ++ + Y L A++ ++S I+P TG +S ++ + E+GK L L+V D GNP ++S + ++I
Sbjct: 1558 DFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGN--GEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPP------------RFLQA--VYRATILENVPSGSFVLQVTAKSLHGAENANLSYEI-PAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNS-PEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDS--------SSGELS-ARPLDREQHSRYTLQIQASDRGQPKSR-QGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQW--QFAIDGQSGL--ITTVGKLDRELQASYNFM------VLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPAL----IQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKL-LHLEVVARDKGNPPQSSLGLIELLI 2154 HSP 4 Score: 100.138 bits (248), Expect = 8.016e-21 Identity = 145/624 (23.24%), Postives = 263/624 (42.15%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKL-----------IKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENK-DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQL--IFDDKDIGENS--------RI--SISSLTTTCYGPT---EKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKN--HNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL--------KAKHDSISI---DPFTGEISLTK--DIEA-GKYDLFLQVTD 1925
DYE + L + A D G P L ++ +++D+ D+ND P F Y+ V E ++ + I++V+A D ++G+ +I Y++ I + D S F I NSG I L+ PL D+ LTV A D+ + T V++ ++D N++ P Y I EN V + D D G+N ++ +L ++S +++ T + + R+ +DRE + + + +D G P+ + + +++ V D N+ P + +S+ E + ++ +D+D + + + L S+ +SG IR LD E+ Y+ + + N + + V VLD+NDN P + + F ++E+ + +G + I D+ NS R+ +++ LT ++ SGN L V + +D E +++I D N + I++ + + D NDN PEW V + + GT + A DAD+ ++ L Y L +++ ++S+ D TG +SL D EA +Y L +Q D
Sbjct: 995 DYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHF-GIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGT-PAAHAKTRVIVRVLDANDNDPKFQKSK--------------YEFRIEENLRRGSVVGVVTASDLDLGENAAIRY---------SLLPINSSFQVHPVTGE--ISTREPLDRE-LRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGG--NPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGN-----------LVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPV----GTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALD 1573 HSP 5 Score: 90.1225 bits (222), Expect = 8.846e-18 Identity = 143/636 (22.48%), Postives = 256/636 (40.25%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQ-KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPAL-FTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFN-EFHLNSSNNFNMESFHLSSLTQSSGEIRIGNP---------------LDREKSPRY-----------------------------------QFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK---ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH----DSISI---DPFTGEISLTKDIE 1889
D E ++ LQ+ A D GQP+ + I + D ND AP+F YT VQED +G+ ++++ A+D + G +++Y L + +IDG SG I + +D+ V A D + + V I ++D+N++RP + YP Y ++ + + +D D G N ++ + + ++ R+N +T L QS+ E L+ + +D G P S ++++ + + + P L F Y + + EN + + +L + D +F + N + S L SL SGEIR+ P L R ++ Y + + +V D S+A + + + D NDN P++ + + E N + Q+ D D G N+R+ + GN D ++ E I++ +D E K+ I DEG P+ +I V I+D NDN+P +P +N+V +S + G +T + A D D+ + LTY L A+ +++SI D ++G++ L + ++
Sbjct: 1910 DREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQ---FAIDGQSGLITT---VGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRP-------------IFERYP-YIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAEN-----SAVSAKFRINPST--GALSASQSLASES-GKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILS--LDSL---SGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRY-----------HIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQP--TFPP--NNLVTVSEAT-ELGAVITSISANDVDTYPA--LTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLD 2494 HSP 6 Score: 89.7373 bits (221), Expect = 1.112e-17 Identity = 152/619 (24.56%), Postives = 260/619 (42.00%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDIDKL-TLTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISV--GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQD-----ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYVGRMSF---EMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI------LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWI---YPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK-DIEAGK----YDLFLQVTDNGNPMRNSSA 1955
D E P + L + A D G P L + I I D+ND P F Y V E+ VG+ +L+V+A D ++ + G + Y + + + ID +G I + K L F+ +L L V A D E + T V I + DVN+++P I+V SD + + P F+ + + + + NV G +G F L +R + Y + + +DRE VSN S+ D G P L ++ + + + D N+ P F + Y +++E D S+L D+D AL+++ L + + + F + T G I + +D E P Q ++ A+D +S ATV V + D+NDN P + SF + EN + ++ D D G N+ ++ + E ++E ++ + + +D+E + + + D G I + + D NDN P + Y SL S + S T + V A D D + +++Y + A +++ ID TGEI + + D+ + + + L + TD GN N+ A
Sbjct: 245 DRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQ--PLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGH--------------FALTTR-----DNSIYLVIVHLPLDREIVSN-YTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYS---LAETPETHAQWFQIDPQT---GLITTRSHIDCETEPVPQLTVV----ARDGGVPPLSSTATVLVTIHDVNDNEPIF--DQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTI--------------GEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKM--QLTDVNDNRPVFYPREYKVSLRESPKAS--SQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADA 811 HSP 7 Score: 74.7146 bits (182), Expect = 3.967e-13 Identity = 139/571 (24.34%), Postives = 241/571 (42.21%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDF---STSFVSIDGNSGTIILKKPL-FDIDK-LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFL------EIFENNPENFEVSFINVVDKD-EGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDAL--SFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVN----EAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPS--YELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL--KILQVKQSMDYE-FIHNCKIDIHFHDEGFPKNHNKISII------VNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL 1820
D E + L++IA D G PQ+ + + + I+D+ND P F N V E +G+VI + A D ++ + + Y+L + S ++D SG ++LK+ L +++ + L V A D+A H ++ + + VN+ N V L P YF EI E+ +F++ +N D D EG N V I+ + ++ + + +N + Q + S I +D G+P LKS+ +L+V D + F ++ Y I E S++ + QDAL S N + F L QS + + PLDRE++ Y+ + + + + +S +V + +LD NDN P + +E + + + Y + QL D D EN+ S Y T SGN++ + +L +L V +DY+ + ++ I D +H++ + + + DENDNEP++ L V+ N G+ + R A D D +L Y +
Sbjct: 2387 DREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLV-TVSEATELGAVITSISANDVDT--YPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAA-HEAR------TVLTVRVNDENDNAPV--------FLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAV---------SSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVV--LQLGQDALDQSLAIIAGNEESAFE--------LLQSKAIVLV-KPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDAD-QENTPNS-----EVVYDIT---SGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACD-----SHHQRPLCSLQPFRLELHDENDNEPKF----PLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSI 2901 HSP 8 Score: 52.7582 bits (125), Expect = 2.307e-6 Identity = 51/209 (24.40%), Postives = 87/209 (41.63%), Query Frame = 3
Query: 195 DYEFIPK-FVLQLIACDIG-QPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKL--IKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVG----SDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI 797
DY+ K + L + ACD Q LCS Q +++ D ND PKF Y + E+ VGS + + HA D + G FG++ Y + +++ S +D SG ++ +FD E ++D + D+ + +++V S + Q + L P+ + V + D D G +G V Q+
Sbjct: 2819 DYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESG-LVTSAFVFDY-------------EQRQRYDME---LLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQL 3010
BLAST of Protocadherin vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 125.946 bits (315), Expect = 8.944e-29 Identity = 156/633 (24.64%), Postives = 274/633 (43.29%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLI---KNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENN--PENFEVSFINVVDKDEGK-NGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQDALSFNEFHLNSSNNFN-----MESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNT---KFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYEL---GQLIFD----DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHF------HDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAK--HDSISIDPFTGEISLTKDI----EAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E ++L + A D G+P + +L+I I+D ND +P F K Y+ V E+ ++G+++L+V A D + G G+I Y ++ +N DF SI ++G + + K L + + +LTV A D A N D + I I+D+N++RP L+ Y + EN P V +N D D N V+ ++ +LF R+N ++ L + +DRE+ S ++ D G P L T I++V+V D N+ +F +Y ++ EN +L+ D+D LN+ FN M FH+ S T GEI LDRE++ Y ++ AQD++ S +++ V D+NDN+P+ F+ N+ E G+ +F D D GEN+ + + +SG + ++ K V ++ + D+ + D+G +K + V IL + P + Y + N +++ G +T+V A ++ Y + DS+ +DP +G +S+ +D Y+++++ D P S +T+ + N
Sbjct: 2237 DRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDF-----SISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPT------------FLDS--PYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGD--SDLF------RINASSGDIAL--LKPLDREQQSE-YTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDE------GLNAKLRFNLLGEHMHRFHIDSET---GEISTATTLDREETSVYHLTLM----AQDSSITEPRASSVNLTISVSDVNDNIPK------FDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYT------------ISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAY---MANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDAN 2804 HSP 2 Score: 122.094 bits (305), Expect = 1.585e-27 Identity = 156/608 (25.66%), Postives = 258/608 (42.43%), Query Frame = 3
Query: 222 LQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREK-------------VSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDA-------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMS-FEMKENNIPSYELGQLIFDDKDIGENSRI--SISSLTTTCYGPTEKLSGN-EDLFWISEL-KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSI------SIDPFTGEISLTKDIEAGKYDLF---LQVTDNGNP 1937
++L+A D G P L S L + I D+ND P F +Y + E V + + A D + GD G+I Y++I+ V D G + ++ PL + D LTV D+ + S+ VVI +ID N++ P Q N + I EN P + V + VD+D G+N ++ + + F +D+R K + + R N + DNG P L+ + ++V V D N+ F R+ Y ++I E + ++ V QDA + ++ N + FN++S ++G++ +G LDRE + I V +A +S A++++VVLD NDN P++ S + E + EL + D D G NS++ SIS +GN D F I + L + + +DYE I + ++I D G P + V ++D+NDN P I+PS+ +V I T + V A D DS + +++Y + + + I+ TG I ++I+ D F + TD P
Sbjct: 1017 VELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFPD---GYLFVRAPLDREERDYYALTVSCRDAGQP-SRSSVVPVVIHVIDENDNAP------------QFTNS--TFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQ---TQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITH-VFTQDADEGLNGDVYYSLAKGNEAGQFNLDS--------ATGQLSLGRRLDRESQEIHHL-IVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSIS-------------AGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPP--IFPSTA--IVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQP 1576 HSP 3 Score: 119.398 bits (298), Expect = 1.073e-26 Identity = 149/617 (24.15%), Postives = 257/617 (41.65%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNE-----DFSTSFVS----IDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI-LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISII-VNILDENDNEPE-----WIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSI-SIDPFTGEISLTKDIEAG-----KYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + A D G P ++ + I+D+ND P F +Y + E G+ ++ V A D + GD KI Y L + E + T +S ++ T + T+ H S + + T+V + ++D N+H P IS +G + ++ EN V+ + V D D G NG +I + L + RL + + +R+ +DRE++ N ++ D G P +T L +DV D N++ +F +S YS + E S + S D+D + H + + ++ F + LT G I PLDRE + SI + N KF ++ + V++LD ND PQ+ R + + E+ P + + D D G N S+T E+L + F + L L ++ +D E + +I + D+G P + + + +N+ D NDN+P+ +IY + D+ ++ L V A D D + + Y L++ + + +D +G ISL D A Y L + D G A + I++
Sbjct: 229 DRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGR---TYVTVNLLDTNDHDPIISF-------RFFPDGGKVATVD--ENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHF-------RLEEAADLHIVRVNGVLDREEIGK-YNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLT---GLIVTTGPLDREIRDTVELSI-SARDGGPNPKF-AYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTN-----GSVTFALAPSVERLYPLQ--FALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGEGLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVL 813 HSP 4 Score: 116.316 bits (290), Expect = 8.674e-26 Identity = 157/672 (23.36%), Postives = 284/672 (42.26%), Query Frame = 3
Query: 27 KVSEAGKAFQNPRIRIDSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFV-AKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTL---TVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAV-IDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDI-GENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNC-KIDIHFHDEGFPKNHNKISIIVNILDENDNEP-----EWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSANLTIIIYQQNM 1988
++S+ F + +D +N V HY + + + + +S + K+ ++ + + + + A D G+ L S +L + I+ + P F N + ED+ G +I KV A + G GKI Y + + +D NSG + + + D + L +EA D + S T + + + D N++ P + QL IY E+ E ++ + D+D G NG+V ++Q D + ++ Y R +DRE++ + F + D G P + T + + +LD+N+ P FTR +SL++ EN + I SF + + L + N+S +F+ + SG I + LDRE+ Y + + A + + +++ + D NDN P++ SF E +GQ+I D+D G NS IS S P+ S + + K ++ K S N + + D G P +++ + +NI+D ++N P E++ P D V G ++ RV A D + +N + Y L + S S+ G I+L K I+ +Y+L ++ TD G P ++ + I++ +NM
Sbjct: 2608 RISKGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDL-TYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGG--IMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAAD-GDTPSLRSVTLITLNVTDANDNAPVME---------QL-----IYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQND--------FDGTFEITESGEIY---TRMRLDREEIGD-YAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRL-FSLNVTENAE---IGSFVIRVTSSDLDLGA-NANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDGA-----WRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYS-----LQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAV---------RGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENM 3224 HSP 5 Score: 103.99 bits (258), Expect = 5.741e-22 Identity = 139/558 (24.91%), Postives = 238/558 (42.65%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYL------DSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQV--DVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSF-NEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGP-TEKLSGNEDLFWISELK---ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPS---SLDNVVNISHINIQSGTKLTRVRAIDADSVSSNR 1805
DY+ I ++ L + D+G L S L I + D+ND P F K Y + E+ VG+ + + HA D++S I Y + + F+ ++ ++GTI FD ++ TL ++A + +S + ++ + ++ VN P Q L P++ ++ E + V + DKD G++G V +YL D R++ NT + + + +DRE N + ++ ++ G T QV + D N+ P F + Y+ +I E + + ID+D + N+F + N +SF + T GEI + LDRE++ Y I ++ T ATV + + D+NDN P + ++ + EN + LI D D+ N GP T +L G + W+S + +++ S D E + I D G PK ++ + + +LD+NDN PS SL V++ + ++ S KL VR D D V R
Sbjct: 3293 DYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFI-MNQSNGTIS-SAVSFDYEERRIYTLQIKAKNP--DSSMESYANLYVHVLGVNEFYP------------QFLQ--PVFHFDVSETSAVGTRVGAVQATDKDSGEDGRV-------------YYLLVGSSNDKGFRIDTNT--GLIYVARHLDRE-TQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQT---GEISTASRLDREETSTYNLVIGAIDTGL--PPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNG------------GPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDN------PSTTRSLHIAVSLFNGDLPSNVKLADVRPNDIDIVGDYR 3792 HSP 6 Score: 101.293 bits (251), Expect = 3.261e-21 Identity = 155/615 (25.20%), Postives = 247/615 (40.16%), Query Frame = 3
Query: 282 IDIIDINDEAPKFV---AKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLI--KNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDS-AEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI--QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN--KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQS------SGEIRIGNPLDREK---------------SPRYQFS---IFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYVGRMSFE--MKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNE--DLFWISELKILQVKQSMDYEF--IHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I IID+ND AP F T + E+ AVG I DR++G +I Y L N+ F V +G + L++P+ + VE + A + + I DVN+H P S Y + E N + D D G NG + +I T+ + +F + Y L +R +DRE+ + +++C+D GQP S + + + V+D+N+ FT S ++ SI EN D F + +D+D E SF LSS TQ +G I+ P DRE S R + + + DN + V V+V D+NDN P+++ R + + E + + D D G N + S GNE S L + + +D E IH+ + P + N SI + +LDENDN PE+ SS +V+ S +GT+L R RA DAD ++++ + + A + D+ ID TG + L K + + Y L + +D G P +++ +++ N
Sbjct: 930 IAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPV-----TGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTS--------------YETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVF---------PDGY---LFVRAPLDREE-RDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTF-VGKLTAVDRDIGRNAEL-----------SFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFL-RAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYS-----------LAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNA-SITIVVLDENDNAPEFTQSSSEVSVLETS----PTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDN 1483 HSP 7 Score: 99.3673 bits (246), Expect = 1.254e-20 Identity = 153/651 (23.50%), Postives = 268/651 (41.17%), Query Frame = 3
Query: 195 DYEFIPK-FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN------------KD----NFSILSFAVIDQDALSFNEFHLNSSNNF----NMESFHLSSLT------------QSSGEIRIGNPLDREKSPR-YQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI--------LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW---IYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYE--LKAKHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNG--NPMRNSSANLTIIIYQQN 1985
D E P+ + +++ A +G S K+ + ++D ND P+F+ + V EDL +G I + A D ++ G + + L+ D F+ ++ ++G +IL L K L + D ++ + I + D N++ P L +Y +I EN ++V I D D G+N + + + + + LN T L R +D E+V + + + QDNGQP L +TI + +VLD N+ +F +YS + EN KD N ++ +++ D S EF ++S+ N++ H S+ T S E+ + +SPR YQ + Q + +S V++++ D+ND VP ++ + EN + + + D D G N I K + +ED+ L L+V ++D E + ++I D G P + +++ ILDENDN P + Y +S+ +I G + +V A D D ++ R+ Y L ++ SI TG + + K++ +Y L ++ D NP +A LTI I N
Sbjct: 1781 DREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDT--LGSVTFLLMDGHD--GKFL-LEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYTEAY----ATIQVSDTNDNPP--------------LFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSD-------WANDVFSLNPQTGMLTLTAR--LDYEEVQHYI-LIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDS--EFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDY----------LMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASI-------GAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPA-GDTAELTINILDIN 2378 HSP 8 Score: 98.9821 bits (245), Expect = 1.563e-20 Identity = 147/626 (23.48%), Postives = 260/626 (41.53%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKL-IKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT-LTVEAHDSAEHNSKF-----------------------DWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNG--QPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIP-SYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKIS---IIVNILDENDNEPEWIYPSSLDNVVNISHINIQSG--TKLTRVRAIDADSVSSNRLTYEL-KAKHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNG--NPMRNSSANLTII 1970
+ L + D GQP S +VI +ID ND AP+F +T + E+ + + K+ A+DR+ G ++ + L + +DF +ID +G I +P FD + L ++ A S E S D V + + DVN++ P + L Y + I E E ++ + D DEG NGDV +L + + N ++ +L + + +DRE S ++ I + + L S + + VLD+N+ FT+S+ +S++E + ++ F D D ++ + S ++FH+ S+T G + + PLD E Y +I + ++ +V+V+D NDN P + + IP + + DD D G N ++S + P + F I +E ++ + +D E I ++ + D P + + V + D NDN P ++ S++ + + G T + +V A DADS S+ +TYE+ + + TG I+ T + +Y L L+ TD + R+S +TII
Sbjct: 1119 YALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDF-----TIDTRNGFIKTLRP-FDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAP------------EFLRA--PYHVTISEGASEGTHITHVFTQDADEGLNGDV---------YYSLAKGNEAGQFNLDSATGQLSLGRRLDRE--SQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSIT---GSLYLHKPLDYEDITSYTLNITASDCG--TPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGR------HFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFV---SMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITII 1699 HSP 9 Score: 86.2705 bits (212), Expect = 1.329e-16 Identity = 142/617 (23.01%), Postives = 257/617 (41.65%), Query Frame = 3
Query: 249 QPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIY--KLIKNEDFSTS---FVSIDGNSGTIILKKPLFDIDKL--------TLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNG-QPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN---KDNFSILSFAVIDQDALSFN---EFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFD----DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPK-NHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS-ISIDPFTGEISL-------TKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQS 1997
Q +L S+ K+ I I D+NDE P F++ N T ++ E++A+ +V++ V A+D + G G I Y K ++ED S S++ G + + +D L L + A D E + + ++I I+D N++ P V K+ Y + EN V ++ D DEG NG ++ I D + + +R+ ++++ E++S + ++ +D + T L +++LD N+ F S Y ++EN + +L+ D D N + L ++ L + SSG+I + PLDRE+ Y ++ ++ + T V V V DINDN P + + N+PS G + DKD G N+++ + L + F I SE + ++D E + + D + + +++ +++ D NDN P+ + S+ NV I+ G + RA+D D + + Y + + I+ TG +S TK + Y + + D G +S A LT+I+ +F +
Sbjct: 2144 QQRLSSTVKVTILIKDVNDEVPVFISANETAIM-ENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRV------VDALDRELRSSYLLNITARDRGEPPQSTE-SQLLIRILDENDNSP---VFDPKQ-----------YSASVAENASIGAMVLQVSATDVDEGANGRIRYSI---------VLGDQNHDFSISEDTGVVRVAKNLNYERLSR-YSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDS------DLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTG--SPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPS---GTHVLTPRATDKDEGLNAKLRFNLLGEHMH-----------RFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPK--FDSTTYNVAVPERIS--KGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPT 2702 HSP 10 Score: 78.9518 bits (193), Expect = 2.408e-14 Identity = 144/632 (22.78%), Postives = 257/632 (40.66%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED--FSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFII--DVNNHRP-----NISV-----GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTY--------QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLN--SSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSP-RYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP---EWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIIIY 1976
DYE I + L + A D G P L ++ + ++D ND P F + + ++E + + + I+ V A D +SG GK+ Y + K E I+ +G I + + ID LTV A D A+ + + T ++ +I D+N++ P N ++ + K +ST ++ ++ D D NG V +I + + LF +L +NT Q+K +R + + + + + TII ++ P RS S S+ EN+ SIL+ V A + E+ + ++ + L + G + LDRE P Y+ ++ + A TS V V VLD ND+ PQ++ + + E+ + + L D D ++ S+T + G++ F + L + ++D E ++ I D + + + + D NDN P + +Y + N Q G ++ ++ A DAD + +L+Y + + +D S++P TG ++LT + E Y L +Q DNG P S + TI +Y
Sbjct: 1448 DYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQ---------------------VHAKDADSSSNGLVTYEIVSGP--QELF------KLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSE-----VYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILT--VTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAI--ALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPD-------TLGSVTFLL------MDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSDG---VQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPE-------NAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQP----SLSTTITVY 2014 HSP 11 Score: 77.7962 bits (190), Expect = 5.465e-14 Identity = 137/631 (21.71%), Postives = 254/631 (40.25%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIA--CDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAV--GSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNG--QPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE--NKDNF--------------SILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP--QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP---EWIYPSSLDNVVNISHINIQSGTKLTR-VRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
+YE + ++ L + A C + P + +L I+I+DIND P F+ Y V E+ G +L V+A D ++ + +K D + I+ +SG I L KPL + TLT+ A D+ + T +V + + D+N++ P + S Y + EN P V DKDEG N ++ + + + F++DS ++ ++DRE+ S + ++ QD+ +P S++ L + V D N+ F + Y++++ E +K F +++ + + +D + F +N+ L + T+S ++ ++I + Q +S A ++V+ L + P Y+ F M E+ P + ++ G +I + + G + ++ N L + + +DYE H +I I D P + I +N+ D NDN P + IY N + +S +L V+A D DS + + Y L+ D +GEI + E G Y ++ D G P +A++ + + +N
Sbjct: 2342 NYERLSRYSLTVRAEDCALENPA-GDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGD--SDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTG--SPPLTGTGIVRVEVQDINDNDPVFELQS--------------YHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHR--FHIDSETG--------EISTATTLDREETSV-YHLTLMAQDSSITEPR-ASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQ---HYFDINTKTGVVSTKLELKTKTKSHDDL--------------TYTIVISAMDQGEQSLSSKAELTVI-LRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYA-IAGGIMGDSLRVDPNSGLLSVGQ-------DGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIY--------NAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKN 2907 HSP 12 Score: 73.1738 bits (178), Expect = 1.277e-12 Identity = 133/604 (22.02%), Postives = 237/604 (39.24%), Query Frame = 3
Query: 213 KFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLI---KNEDFSTSFVSIDGNSGTIILKKPL-FD-IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDRE-KVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDAD-SVSSNRLTYEL-KAKHDS-ISIDPFTGEISLTKDIEAGKYDLF---LQVTDNGNPMRNSSANLTIIIYQQN 1985
++ L + A D G P ++VI + N + P+F +Y +V E+ VGS IL V A D ++G G + Y + + +DFS +D +G I++++ L +D I + L + D H + I + DVN++ P + N + Y I EN P V + DKD KN + + ++ F ++ + + R+ + K NP ++S L V VL NE+ F + + + E + + D+D+ + + N + F + + ++G I + LDRE R ++ N T A V + + D ND P+++ P +G + K I ++ R + + + K S D+ + + +D E + I D G P ++ + + D NDN P + P L+ ++ N +GT + + A D D + TY+L KH S +S+D +G + T + + ++V D+G P + S LTI + QN
Sbjct: 3194 RYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFS-----VDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLS-SVAMLTIILTDVNDNPP-------------VFN-HKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNP-----------DSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDT---NTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDP-PEFIKHYYTSTISEAAP---VGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDV----QTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFT-PEGLNGYISE---NEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQN 3751 HSP 13 Score: 71.633 bits (174), Expect = 3.962e-12 Identity = 136/644 (21.12%), Postives = 265/644 (41.15%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIG-QPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKN-EDFSTSFVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVS----------FINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNP-LNFSINCQDNGQPLLKSTIILQV------DVLDQNEYPALFTRSNYSLSIIENKDN---------FSILSFAVIDQDALSFNEFHL---NSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSF----ATVSVVVLDINDNVPQYV----GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL-KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFT-GEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E L + A D G P+ +Q VI I+D NDEAP+F + + ED +++ + A D + G G + + L + E ++D +G + ++PL D +K++ ++V A D + V + + DVN++ P YP +++ ++ ++ ++ + DKD+G N ++ ++++ + LF LD+R + +R P ++ +D GQ + I+++ ++L+ + A Y ++E+ + I+ + A S E+ + + + NF +++ SG I PLDRE+ Y+ +I + + + +S V++ ++D+NDN P + + + EN E+ D+D G NSRIS SLT P ++ F I + +L +++ + E +++ D G P +K+S+ V I D ND+ P + + S ++ + +N T+ + A D D + R++YE+ + F G + + + E Y L + D G P R+S + I + +N
Sbjct: 558 DREIRDTVELSISARDGGPNPKFAYTQLKVI-ILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPL-DREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQF---------------YPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGG--EGLFQLDAR--------SGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQA----GGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDT--------RSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISY-SLTNN---PNQQ-------FRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVN----TRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDEN 1147 HSP 14 Score: 71.2478 bits (173), Expect = 4.651e-12 Identity = 139/621 (22.38%), Postives = 255/621 (41.06%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSA-EHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFH-LSSLTQSSGEIRIGNPLDRE-----KSPRYQFSIFVVNEAQDNTK--FTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYE---LGQLIF-----DDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHD--SISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
DYE + + + A D P L S + +++ D ND AP Y V E+ + +I V A DR+SGD G +IY+L DF +F + SG I + L +I VEA D H + V++ ++D N++ P + ++ L + EN V + D D G N + F + + + + +DRE+ + + D ++ + + + DQN+ F S YS S E + + +++ + A ++ NS +++++ + S+ ++GE+ + + +SP +++ V+ A DN K S V++ ++D ++N P+ FE E P + GQ I D +D+G N + S +T + + S WI+ +K +QV + YE + + D G P ++ +++ + EN + P + S+++ I N G+ + V A D D+ + L Y + ++ S+D TG I + + ++ +Y L + V D G +S A LTII+ N
Sbjct: 2769 DYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRL--QNDFDGTFEITE--SGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTG--TASVLLHLLDKNDNPPKFTR---------------LFSLNVTENAEIGSFVIRVTSSDLDLGANANASYS----------FSENPGEKFRIEPQSGNITVAGHLDREQQDEYI-LKVVASDGA---WRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQII----ATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVL--ATDNGKPPLYSECLVNINIVDAHNNPPK------FEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTN-EMDYSLMT---FNLSSIFSVGRHDGWITLVKPIQVPPNTRYELV------VRATDRGVPPQSDETRVVIVVTGENMDTPRF----SVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVN 3328 HSP 15 Score: 66.2402 bits (160), Expect = 1.669e-10 Identity = 114/518 (22.01%), Postives = 202/518 (39.00%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKN--EDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDW---THVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKD-EGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK-DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSL---TQSSGEIRIGNPLDREKSPRYQFSIFVVNEA----QDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENS--RISISSLTTTCYGPTEKLSGNE--DLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP 1685
D E I + + A D G P + + +++ ++D ND PKF + ++ V E+ +GS +++V + D + G Y +N E F I+ SG I + L D+ L V A D A W T + I I D N++ P + Y E V I D+D +G N + +Q +F +D + + +R + S N ++ DNG+P L S ++ ++++D + P F ++ Y + ++ I+ D+ L NE ++++ +F+LSS+ + G I + P+ + RY+ + + D T+ V +VV N + P++ V + EN + + D D G N R SIS GNE D + ++Q +DY+ I ++I D G+ + + + + D NDN P
Sbjct: 2872 DREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFT-RLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFR-----IEPQSGNITVAGHLDREQQDEYILKVVASDGA-------WRAETPITITIQDQNDNAPEFE--------------HSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPS---PMFSIDPAT--GEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEM------DYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETR------VVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISG-------------GNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPP 3332 HSP 16 Score: 65.855 bits (159), Expect = 1.993e-10 Identity = 88/359 (24.51%), Postives = 152/359 (42.34%), Query Frame = 3
Query: 975 IILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALS---FNEFHLNSSNNFNMESFHLSSLTQSSGEIR------IGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFA--TVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFI---HNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP--EWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADS----------VSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTI 1967
I +++ VLD N+ F + ++S E+ + + +L A D D +++ + + N N F L + SG+ GN LDRE YQ +I A+D F V+V +LD+NDN P + + + E +P + ++ D D+G+NS+I+ T + + N + IS + + Q + + +C + D G P+ + + VN+LD ND++P + + V + N +GT + V D+DS VS N L + + + I G + E GKY+L + D G P R ++A+L I
Sbjct: 140 IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDN--KFRLVTTANPSGDTSYLHLETTGN-LDRESRGSYQLNI----SARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETE-----HQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDE-NAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDRE---EIGKYNLTVVAMDQGTPARTTTAHLII 482 HSP 17 Score: 63.1586 bits (152), Expect = 1.266e-9 Identity = 120/593 (20.24%), Postives = 238/593 (40.13%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFG-----KIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT-----LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPAL-----FTRSNYSLSIIENKDNFSIL-SFAVIDQDA-----LSFNEFHLNSSNNFNMES---FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE---LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSI-----SIDPFTGEISLTKDIEAGK---YDLFLQVTDNGNPMRNSS 1952
I ++D+ND +P+F + E G+ +L A D + G+ G +I+ + N+ + + G++ + L+ ++D+ + L + A D +F + V + I+DVN++ P I SD Y + + E V + D D G N + + T ++ F ++ + T + + ++ F++ +D+G P + V++LD N++ + F ++ EN N +++ + AV D D+ S N +F +E H+ +R+ LDRE+ +Y ++ ++ Q T+ A + + V D+ND+ P + S + E + + D+D G N+++ + LSGNE L W S ++ +D E ++ I D G + V ILDEND P++ S + V + + T + + A D D ++ +T+ L + + ++D TG+++ + ++ K Y++ + D G P S+
Sbjct: 144 IKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLET-TGNLDRESRGSYQLNISARDGGSP-PRFGYLQVNVTILDVNDN-PPIFDHSD-------------YNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAET---EHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHI---------VRVNGVLDREEIGKYNLTVVAMD--QGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHY-----------DILSGNE-LKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQF---SQREQNVTLGE-DAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSA 690 HSP 18 Score: 52.373 bits (124), Expect = 2.515e-6 Identity = 60/238 (25.21%), Postives = 106/238 (44.54%), Query Frame = 3
Query: 1176 SLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDI 1886
+L +GE++ LDRE R + + V++ ++ T V + VLD+NDN P++ ++ E+ L D D+GEN + +L + + L+ ++D E + +++I D G P + + V ILD NDN P I+ S D V+++ + GT + V A D D ++++TY L +++P TG IS T+ +
Sbjct: 104 TLDPVTGEVKTNVVLDREGM-RDHYDLVVLS-----SQPTYPIEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPP--IFDHS-DYNVSLNETAL-PGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERV 331
BLAST of Protocadherin vs. Ensembl Fly
Match: Cad87A (gene:FBgn0037963 transcript:FBtr0082513) HSP 1 Score: 112.464 bits (280), Expect = 1.068e-24 Identity = 159/644 (24.69%), Postives = 272/644 (42.24%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILK-KPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINV--VDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDN-GQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-----NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNED-LFWISELKI-LQVKQSMDYE--------FIHNCKIDIHFHDE--------GFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADS----------VSSNRLTYELKAKHDSISIDPFT----GEIS---LTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIY 1976
DYE + + Q+ D G P L ++ +V+DII++ND PKF +Y V E+ G+V KV A D + G FG+I Y LI + + SID +G +++ + D I +LTL+V A D A + T + I I+DVN++ P + +Y + EN + + V +D+DEG GDV+ I + LF LD++ + + QS+ + + L +I+ +D G ++ST + VL N + F S + IE + ++ +L+ +D D + +HL NN N + + + +GE+R L+R+ R + I +V N F S +SV ++D N+N P++ +N + + D IG S S + L GNED F++ +L + +S+D E + + K D+H +E +++ + + +LD NDN P + P V + N + G +T V A DAD V+SN + SI PF G IS + + +++L + + P ++S + I ++
Sbjct: 1062 DYEVVKEVKFQVTVSDTGVPALTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGENN---KYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFT--------------RDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGNEM-GLFKLDAQSGI--------VYPAQSLSGKHGAYEL--TISARDTQGSGTMESTTKAIITVLRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQ-VNNRNEQQTGEFKIDEVTGELRAKTQLNRKN--RANYDIILVARDAGNPPFESLRLLSVSIVDANENRPEF-------PDASNPYKVSINENSGRDVKIGHIQAASRSKHNRDIF--YYMLLGNEDGAFYVDKLTGDIYTNKSLDREETDVYTLYILASIKADLHISEEERASFSIKTLNRDNTVAKVAITVLDVNDNPPVFEKPIYYAGV----NANAKMGAAITLVNATDADQGKNAKIEFMIVASNLYKFGATKSTGSIVPSPFAISQDGRISANTIMAEYNQDRFELEIVARELEQPQSSASTKVNIWVF 1661 HSP 2 Score: 95.9005 bits (237), Expect = 1.373e-19 Identity = 142/635 (22.36%), Postives = 261/635 (41.10%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIY-------------KLIKNEDFSTSFVSIDGNSGTII---LKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVG---SDKRTSTQLLNGYPI-YFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFNE--FHLNSSNN--FNMESFHLSSLTQSSGEIRIGNP--LDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNI--PSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKL--SGNE-DLFWI-SELKILQVKQSMDYEFIHNC-KIDIHFHD-EGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA------KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
+ LQ+ A D G P L + L I++ + ND+ P FV V+ D G ++ + A+D + + + + K + + D + I N + L + LF + ++ + V DS N + ++I IIDVN + P + + Q++ P+ L + N E+ + N+ D D QT+ ++ + LD +V + F + D G P L +T + VD+++ N+ F++S+Y ++ EN ++ D D F E + L NN F+++++ +G + + N LDRE+ S+ ++A + ++ AT+ + +LD+NDN P + + + + EN P L Q+ D+D G YG + +GNE LF + ++ I+ QS+ + H ++ I D +G + I+ +L N ++PE++ P+ + + I +Q L VRA+D D+ + +++Y L+ + ID TGE+ + YD+ L D GNP S L++ I N
Sbjct: 844 YQLQIQASDQGTPSLTGTATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDKEGKELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLVT--DSTAPNVQQGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSIGEFNISDND------YFAINQTSGMIYTIARLDY----------------------EVVKEVKFQVTVSDTGVPALTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGENNKYFSIDAY--------TGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEG-------------LYGDVRYIITAGNEMGLFKLDAQSGIVYPAQSLSGK--HGAYELTISARDTQGSGTMESTTKAIITVLRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGEFKIDEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDAN 1425 HSP 3 Score: 88.5817 bits (218), Expect = 2.069e-17 Identity = 132/582 (22.68%), Postives = 227/582 (39.00%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKK-PLFDI-----DKLTLTVEAHDS--AEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSIL-SFAVIDQDALSFNEFHLNSSNNF---NMESFHLSSLTQ--------SSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFE---MKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS-ISIDPFTGEI 1868
DYE + L A D S L I + D ND P + Y V E V L V A R++ +I Y++ +E + F ID +G II++ D+ D+L VEA+D H V I + DVNNH PN S Y + EN+ V ++ D D GKN +++ +IQ + + T + + + DR N I D G P L T L ++V + N+ F + + + ++ + +D D + N +++ + E L Q +G++ + LDR + ++ V + N + + + ++D+N N P++ S E +K + +G ++ + E+S I +++ Y + SG ++ I+ L DYE + K + D G P ++V+I++ NDN+P++ S D N++ N GT +V A D D +TY L +++ SID +TG +
Sbjct: 628 DYESETTYFLSYKATDDNGRGSASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFDSPLIVKA--RDADTMSRISYRIRGSEQVESIF-DIDRETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAH------CGVNITVRDVNNHVPNFEQQS--------------YSAVVEENSEIGTSVERVHATDLDTGKNAELRYRIQQGSF--------DDFGIVETTGEVFVSRKLDFDRR---NTYQLQIQASDQGTPSLTGTATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDKEGKELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLVTDSTAPNVQ-QGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSIGEFNISDNDYFAINQTSGM--IYTIARL---------DYEVVKEVKFQVTVSDTGVPALTATADVVVDIINLNDNDPKF---SQSDYYFNVTE-NSPRGTVAGKVEAHDGDVGVFGEITYTLIGENNKYFSIDAYTGNV 1159 HSP 4 Score: 66.6254 bits (161), Expect = 1.318e-10 Identity = 106/409 (25.92%), Postives = 178/409 (43.52%), Query Frame = 3
Query: 288 IIDINDEAPKFVAKNYTKVVQEDLAVGSVIL-KVHAIDR----ESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGS---DKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNP---LNFSINCQD--NG----QPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSF--AVIDQDALSFNEFHL---NSSNNFNMESFHLSSLTQSSGEIRIGN-PLDREKSPRYQFSIFVVNEAQD-NTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIG 1439
I+D+ND P+F Y V ED AVG+ I K+ DR ES D K + + E + I TI L V +D+ +N + + H I D H+ + + D + + G ++ E++P N V ++ D D G+ + ++T + F LD++ +LR + +DRE + + ++ I ++ NG PL +T V + D N+ P +F YS+S++EN + L+ +V D D ++F L + S F++E ++ +Q + IR+ N LD E + +F + VV E D N + +S AT++V VLD NDN P + S + E +P + + D D G
Sbjct: 122 ILDLNDNPPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDL-KCLPQQQSPEACRKFRLHIIKRDATI-----------LEAAVVLNDTLNYNQRMVY-HFQIEATD-GPHKTQTTFEARVKDVQDKPPVFQGSLSTVID--EDSPINTLVLTVHARDGDTGEPRKIVYDLRTNP--NDYFLLDAQTG--------ELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDVSGVFDVEPKLVTGYSQVN--IRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAALPGQYIATITARDVDSG 502 HSP 5 Score: 58.151 bits (139), Expect = 4.486e-8 Identity = 114/495 (23.03%), Postives = 198/495 (40.00%), Query Frame = 3
Query: 342 VVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVV-----IFIIDVNNHRPNIS-------VGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKD-EGKNGDVKCQIQTTK-----------LLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD---NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQ--------DNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELG-QLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDL-----FWISELKILQVKQSMDYEFIHNCK---IDIHFHDEGFPKNHNKISIIVNILDENDNEP 1685
++ E++ VG+V+ ++ A D E + Y I + FS +D SG I L KPL + D L V D + + + +VV I+D+N++ P V D T + + I V D+D G++ D+KC Q + ++ L++ + LN +T Y R+ +F I D K+ + V D + P +F SLS + ++D N +L+ D D + + N N + F L + T GE+R PLDRE I +V A+ D+ ++ A +V + D+ND+ P + + S + EN +P L + D D+G NS+ ++ + +SG D+ S++ I ++DYE + K + + + P+ + +I V++LD NDN+P
Sbjct: 35 ILYENVTVGTVVFRLEAYDPEGS---PVTYGAIGADHFS-----VDPVSGNITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPPEFQNTPYEADVNEDAAVGTTIFDK--------------------ITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHIIKRDATILEAAVVLN-DTLNYNQRMV-----------YHFQIEATDGPH---KTQTTFEARVKDVQDKPPVF---QGSLSTVIDEDSPINTLVLTVHARDGDTGEPRKIVYDLRTNPN-DYFLLDAQT---GELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALR---------LDDVSGVFDVEPKLVTGYSQVNIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKP 470
BLAST of Protocadherin vs. Ensembl Fly
Match: Cad74A (gene:FBgn0036715 transcript:FBtr0075240) HSP 1 Score: 108.997 bits (271), Expect = 3.126e-24 Identity = 114/448 (25.45%), Postives = 202/448 (45.09%), Query Frame = 3
Query: 96 YHYLLECSQKSHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACD-IGQPQLC--SSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKL---TLTVEAHDSAEHNSKFDW----THVVIFIIDV--NNHRP---NISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTR----SNYSLSIIENKDNFSILS-FAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFT---------SFATVSVVVLDINDNVPQY 1352
YH ++ Q H F +N T + + +++D E P+ LQ+ A D G+P S +L I+++D+ND AP+F K Y+ V+ E+ + S +L++ A+D + G G++ Y+L+ NE + ID SG I ++ L + L V A D+ K T V I+I DV N+ P + VG + + G P++ ++ ++P D + +G + +I F +D+ L + RQS+DRE + + DNGQP +T ILQ+ +LD +++ F R S+S+ E + +I+ F+ +D+D + N + F + +S ++ P+DRE+ + +I + + KF S ++V VLDI+DN+P++
Sbjct: 1093 YHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRYELV-NEGEANGLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVF--QVIASDP-----------DDESTPSGTITYRILPDTPDAEAFVIDAHSGL--------ITTRQSMDRE-TKDMYRILLEVSDNGQPKQSATRILQIAILDVDDHEPRFAREADAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVLDIDDNLPKF 1517 HSP 2 Score: 23.483 bits (49), Expect = 3.126e-24 Identity = 8/21 (38.10%), Postives = 15/21 (71.43%), Query Frame = 1
Query: 7 DINDNSPKFQKLERHFKILES 69
++NDNSP+F++ I+E+
Sbjct: 1045 NVNDNSPRFERNSYQATIIEN 1065 HSP 3 Score: 99.7525 bits (247), Expect = 7.283e-21 Identity = 151/643 (23.48%), Postives = 264/643 (41.06%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIG-QPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFG--KIIYKLIKNEDFST-SFVSI-DGNSGTIILK---KPL---------------FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQ-LLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPL-NFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFA-VIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFD----------DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI----SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI-----------NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLT------KDIEAGKYDLFLQVTDNGNPMRNSS 1952
D+E P ++L + A D +L S + I++IDI D+ P F Y+ V E+ G IL V A+D GD G + I+ +++E F V D GT +L+ +PL F I + T ++ AEH+ T V I + DV++H+P S + T+ L NG P+ L IF V D+D G+N + ++ +F + + K+ +D + V L F + + + + K+ +++ +LD N+ +F + Y + EN +I+ D D+ F F ++F+++ T G + + PLD EK Y ++ ++ Q F V V D+NDN P +FE KE + E G +F+ D N R+ S ++ ++GN +F I E+ I + +SMD E ++ + D G P N ++V + + P I+ N+ N+ I N +G+ +T V A D D + S L Y + +D+ ID +G I+++ +D +++ + D+G P+ ++
Sbjct: 203 DFESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPAGVSILTVKAVD---GDVGIPREIFLSLEDEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSI-RATELIDGAIPAEHS----LTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIF-------------VDDRDMGENSRYELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRY-VLKGFGADNFYVNPET---GGVYLLKPLDYEKQSSYSLTVVAIDGGQREANANLF----VGVTDVNDNHP------NFESKEYSRTIRE-GAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENS------IAGN--VFRIEPDTGEIVIQKAARSMDTER-GEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRP--IFRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPDGLDS-LLRYRIVGANDNFEIDEISGLITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPETA 797 HSP 4 Score: 92.4337 bits (228), Expect = 1.447e-18 Identity = 134/588 (22.79%), Postives = 251/588 (42.69%), Query Frame = 3
Query: 195 DYEFI----PKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDR--------ESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDID-----KLTLTVEAHDSAEH--NSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEV-SFI---NVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNG-----QPLLKSTIILQVDVLDQNE--------YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-----VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE----LKILQVKQSMDYEFIHNCKIDIHFHDEGFP-----------KNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADS 1790
DYE + P+F LQ+ A + Q + ++ I + ++ND +P+F +Y + E+ +++V A+D+ E + KIIY L + I+ +G II+ ID ++ L ++A DS ++K + I ++DVN++ P + K+ ST + PEN ++ SF+ VD DEG G+V+ ++ LF +D++ L + R+++ + ++P + QDNG QP L + +++ + D + P + +N + + + F +++ D+ S + + + E+F + + SG I +DRE Y+ + V + Q T + + +LD++D+ P++ G +S ++E +G D+D+GEN+ I + NE LF I L IL+ K+ +D E + + + I G P ++ + + I V +LD +DN P++ P D V I IN+ T +T ++A DAD+
Sbjct: 1009 DYEALGDTGPEFELQVRANSADR-QRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARDERLGYHKIIYSL---QGEHAMLFDINNTTGEIIVASGQ-TIDRERTPRIQLQIKAEDSPGRPTDAKQSVVELQIEVLDVNDNAPEF---TQKKYSTVI---------------PENAQIDSFVLQLEAVDADEGLGGEVRYELVNEGEANGLFKIDTKSGL--------ISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGTITYRILPDTPDAEAFVIDA---HSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSATRI--LQIAILDVDDHEPRFAREADAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVIID----------GNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVLDIDDNLPKFEQP---DPTVGI-RINVPIDTVVTTLKASDADA 1546 HSP 5 Score: 86.6557 bits (213), Expect = 8.803e-17 Identity = 144/592 (24.32%), Postives = 259/592 (43.75%), Query Frame = 3
Query: 345 VQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWT--HVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSF---INVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNG-QPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSN----NFNMESFH----LSSLTQSSGEIRIGNPLDREKSP------RYQFSIFVVNEAQDNTKFT--SFATVSVVVLDINDNVPQYVG-RMSFEMKENNIPSYEL-GQLIF-DDKDIGENSRISIS------SLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFI----HNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP---EWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA-KHDSISIDPFTGEISLTKDIEAGK---YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
+ E+ VGS + ++ D E G ++ Y + S S+D +G + L++ L D + + + D + ++ + VI + D N+++P G P Y + E+ P E+S I VVD+DEG N +V+ + + ++F + + ++++ Y ++ ++Q +D E + + +I+ D+ L S + ++V+D + P +FT + YS ++ EN SIL+ +D D E L+ + +F + F +++ Q++ E PLDRE + Y FSI E D S V++VV D++D+ P + G + + EN L G IF DD+D+GENSR +S + PTE G + +K+L + +DY+ + + D+ +G K ++ I ++LD NDN P + Y + + + I + V+A D DS + Y LK D+ ++P TG + L K ++ K Y L + D G R ++ANL + + N
Sbjct: 36 LSENTPVGSPVFQLKGTDPEGG---RLKYSI------SGPVFSVDRETGVVRLRQELDRETQDTVEVIISITDEGIYGTEPNTVSQRRVIPVRDYNDNQPTFL-------------GRP-YTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRA-VKISDGNYTARVALKQQLDFESRPSYI-LTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLEDEPFGHFELVPFGDPRDGTAVLQTTSE-----PLDRENAEILQNGGVYVFSIR-ATELIDGAIPAEHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTES-QGRTPVV----VKVLNASR-LDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEI--HLLDANDNAPVFDQGTYRFTAAENLPVDAI-------IGHVKATDLDSGEFGHVRYVLKGFGADNFYVNPETGGVYLLKPLDYEKQSSYSLTVVAIDGGQ--REANANLFVGVTDVN 579 HSP 6 Score: 84.3445 bits (207), Expect = 4.412e-16 Identity = 148/608 (24.34%), Postives = 237/608 (38.98%), Query Frame = 3
Query: 267 SQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVG---SVILKVHAIDRESGDFGKIIYKLIKNED----FSTSFVSI-DGNSGTIILKKPLFDID---KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKL--LKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLN-----FSINCQ---DNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDN---FSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRI------GNPLDRE-KSP---RYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTR----VRAIDADSVS--SNRLTYELKAKHDSIS-----IDPFTGEISLTK-----DIEAGKYDLFLQVTDNGNP 1937
SQ+ VI + D ND P F+ + YT V E L VG SV + +DR+ G ++ K ++ D F V I DGN + K D + LT+ A DSA N + I +ID+ + P + P Y + EN P + + VD D G ++ ++ + + + D R + + +DRE N FSI D P S + + V D +++ F+ ++++SI EN N LS V D+D + + L+ + FN S T+S G + + LD + P +++F + + + K V + +LD NDN P + G F EN +G + D D GE + K G ++ + E + + + +DYE + + + D G + ++ V + D NDN P + I+ G L VRA DAD S + R+ Y + +SI+ I+P TGEI + K D E G+Y+L + TD G P
Sbjct: 111 SQRRVIPVRDYNDNQPTFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGNYTARVALKQQLDFESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPP-------------IFTNAP-YSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLEDEPFGHFELVPFGDPR-----DGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEKAK----TRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRY----------VLKGFGADNFYVNPETGGVYLLKPLDYEKQSSYSLTVVAIDGG--QREANANLFVGVTDVNDNHPNFESKE--------YSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSI-VSENSIAGNVFRIEPDTGEIVIQKAARSMDTERGEYELVVSATDFGIP 674 HSP 7 Score: 69.3218 bits (168), Expect = 1.500e-11 Identity = 107/402 (26.62%), Postives = 173/402 (43.03%), Query Frame = 3
Query: 213 KFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQT-TKLLKNLFYLDSRMRLNKNTYQYKL-RIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDV-LDQNEYP------------ALFTRSNYSLSIIENKDNFS-ILSFAVIDQDAL-SFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKF--TSFATVSVVVLDINDNVPQY 1352
KF L+A G + + ++ I ++D ND AP F Y E+L V ++I V A D +SG+FG + Y L + F ++ +G + L KPL D +K +LTV A D + + ++ + + DVN++ PN K S + G ++ + F + D NG VK I + + N+F R+ +T + + + +S+D E+ ++ D G P L +T + V V + N+ P + +Y +SI EN S + S + D D L S + + +N+ N E +S L S + RI DR+ S F I +VN T T+ TV V V DIND P++
Sbjct: 450 KFEFDLVASVKGVEK--AKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVL---KGFGADNFYVNPETGGVYLLKPL-DYEKQSSYSLTVVAIDGGQREAN---ANLFVGVTDVNDNHPNF---ESKEYSRTIREGAALFEPQFFVRAHD---------ADGPSQGNGRVKYSIVSENSIAGNVF------RIEPDTGEIVIQKAARSMDTER--GEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPIFRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPDGLDSLLRYRIVGAND-NFEIDEISGLITVSPQARI----DRD-SNMNSFEI-IVNAVDSGTPIPETATTTVYVNVKDINDERPKF 815 HSP 8 Score: 58.9214 bits (141), Expect = 2.692e-8 Identity = 112/428 (26.17%), Postives = 179/428 (41.82%), Query Frame = 3
Query: 486 SGTIILKKPLFDIDKLT-------LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRM-RLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDN-GQP--LLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK--DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN----TKFTSFAT---VSVVVLDI--NDNVPQY----VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW 1691
+G +ILKK L D + L L V A+ + S + V I + +VN++ P S Y I EN P V + +DKD N + ++ K++ +L + + +N T + + Q+IDRE+ + I +D+ G+P +S + LQ++VLD N+ FT+ YS I EN D+F +L +D D E N E+ L + SG I L + R + +V AQDN K + +T V + + D+ ND VP + VG+M+ + EN + + Q+I D D + S S T Y E + ++ +QSMD E +I + D G PK + + ILD +D+EP +
Sbjct: 999 TGEVILKKRL-DYEALGDTGPEFELQVRANSADRQRSTV--SRVNITVENVNDNSPRFERNS--------------YQATIIENRPHPERVIRVRALDKDAVLNARDE-RLGYHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPR-IQLQIKAEDSPGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSF-VLQLEAVDADEGLGGEVRYELVNE--GEANGLFKIDTKSGLISTRRNLTGKG--RAHPYVLIV-RAQDNGNQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMA-NVTENAVTGAPVFQVIASDPD--DESTPS----GTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSATRILQIAILDVDDHEPRF 1394
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 186.037 bits (471), Expect = 1.204e-47 Identity = 179/603 (29.68%), Postives = 284/603 (47.10%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISV-GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + A D G P SS L + I D ND APKF +Y V E+ +G +L+V A D + G G+I Y L + D + ID +SG I +K PL +I+ L V A D + K T+V I + D N++ P + + G T + + I E+ P V+ + V DKDEG+N V C + + DS + N +Y L+ +D E+V + I D+G P L ST L+V V D N+ +F+ + + + E N+ ++ V+ DA S L S + + L + +SGE+R +PLDRE RY+F + ++ + + T ATV + VLD NDN P+++ SF + EN P +G + D D GEN+++ +S + +G +S + + K+S Y F + D G P + + + +N+LDENDN P PS+ + + +S + + + V A D DS S+ L Y + HD I P GEI+LTK++ +G + L ++V+D G P R++ A + I +
Sbjct: 202 DRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDREEINNLKFYVVARDKGP-SPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGV-------ANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSV---DNKRKYFLQTTTPLDYERVRD-YRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVE--VVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGT--ATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDVGKFVIQNGTGT----ILSSISFDREKES-SYTF------RLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSN-SSFIRLSPMAAPD-SVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYV 775 HSP 2 Score: 103.605 bits (257), Expect = 6.380e-22 Identity = 144/578 (24.91%), Postives = 239/578 (41.35%), Query Frame = 3
Query: 360 AVGSVILKVH------------AIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIID-VNNHRPNISVGSDKRTSTQLLN------GYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP----QYVGRMSFEMKENNIPS-YELGQLI----FDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS---ISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
AVG ++ +VH A D+ D G + YKL + ++ +DG +G I + ID+ TL + K + + + D + N P + G R Q +N P+ L + EN S DKD +NG + LF L ++ ++ +L + S+DRE + + + +I D G P S+ +L+V + D N+ F +S+Y + EN S+L D D E + L + +SSG I + PLDRE+ +F +VV + + +S VS+ V D NDN P + +G ++ NI +G + DKD GEN+ ++ + +L D ++ K LQ +DYE + + +++I D G P + S+ V + D NDN P I+ +L V + N Q G K+ V A DADS ++ L Y + A + IDP +GE+ ++ +Y+ + D G P +A + I + +N
Sbjct: 21 AVGGILYRVHEEQPPSTLIGSLAADQGLPDTGHL-YKL----EVGAPYLRVDGKTGDIFTTE--IPIDRETLK-----DCRNKGKPCFLEFEVSVTDLIQNQSPRLIEG---RIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGL--QVAEDRGEKLPQLIVLGSLDRE-LKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVP-KLLRIDRSSGIIYVKGPLDREEINNLKF--YVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPF----QLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSP--IFSPTLFE-VEFAEEN-QPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRN 569 HSP 3 Score: 98.2117 bits (243), Expect = 2.418e-20 Identity = 137/600 (22.83%), Postives = 250/600 (41.67%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-VSIDGNSGT-----IILKKPLFDI-DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPA-------LFTRSNYSLSIIENKDNFSILSFA-VIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I++ DIND P+F + T V E+ +G++ A D+++ G Y L + F + + + G I+L ++ D LT++A D + ++ + + I D N++ P S Y E+ EN+P V + D D G NG+++ + Q + L +D + + ++ +DRE+++N L F + +D G S + +DV DQN+ PA L T S+ +I E+ + ++ V D+D E + + F L + SS + ++ PLD E+ Y+ I V+ N +S ++ V V D NDN P + + E E N P ++ +++ D D G N+ + S + S LF I ++ + +D E + + D+G P + ++++ +LD NDN+P+++ S L+N+ +S + + V D D + ++ ++ I TG I S++ D E Y L+ D G+P R+S +TI + +N
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGG-NPPRYSSALLRVVIADANDNAPKFEKSS--------------YEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGI--------IYVKGPLDREEINN-LKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDE---GENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSG--NPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIAD---------SSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGM--------VTVQDMDEGENAQVQLSVEPDVGKFVIQNGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDEN 672
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 185.267 bits (469), Expect = 1.590e-47 Identity = 179/603 (29.68%), Postives = 283/603 (46.93%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISV-GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + A D G P SS L + I D ND APKF +Y V E+ +G +L+V A D + G G+I Y L + D + ID +SG I +K PL +I+ L V A D + K T+V I + D N++ P + + G T + + I E+ P V+ + V DKDEG+N V C + + DS + N +Y L+ +D E+V + I D+G P L ST L+V V D N+ +F+ + + + E N+ ++ V+ DA S L S + + L + +SGE+R +PLDRE RY+F + ++ + + T ATV + VLD NDN P+++ SF + EN P +G + D D GEN+++ +S + +G +S + + K+S Y F + D G P + + + +N+LDENDN P PS+ + + +S + + V A D DS S+ L Y + HD I P GEI+LTK++ +G + L ++V+D G P R++ A + I +
Sbjct: 202 DRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDREEINNLKFYVVARDKGP-SPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGV-------ANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSV---DNKRKYFLQTTTPLDYERVRD-YRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVE--VVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGT--ATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDVGKFVIQNGTGT----ILSSISFDREKES-SYTF------RLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKPSN-SSFIRLSPMAAPDSV-VEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYV 775 HSP 2 Score: 102.834 bits (255), Expect = 8.891e-22 Identity = 144/578 (24.91%), Postives = 239/578 (41.35%), Query Frame = 3
Query: 360 AVGSVILKVH------------AIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIID-VNNHRPNISVGSDKRTSTQLLN------GYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP----QYVGRMSFEMKENNIPS-YELGQLI----FDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS---ISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
AVG ++ +VH A D+ D G + YKL + ++ +DG +G I + ID+ TL + K + + + D + N P + G R Q +N P+ L + EN S DKD +NG + LF L ++ ++ +L + S+DRE + + + +I D G P S+ +L+V + D N+ F +S+Y + EN S+L D D E + L + +SSG I + PLDRE+ +F +VV + + +S VS+ V D NDN P + +G ++ NI +G + DKD GEN+ ++ + +L D ++ K LQ +DYE + + +++I D G P + S+ V + D NDN P I+ +L V + N Q G K+ V A DADS ++ L Y + A + IDP +GE+ ++ +Y+ + D G P +A + I + +N
Sbjct: 21 AVGGILYRVHEEQPPSTLIGSLAADQGLPDTGHL-YKL----EVGAPYLRVDGKTGDIFTTE--IPIDRETLK-----DCRNKGKPCFLEFEVSVTDLIQNQSPRLIEG---RIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGL--QVAEDRGEKLPQLIVLGSLDRE-LKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVP-KLLRIDRSSGIIYVKGPLDREEINNLKF--YVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPF----QLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSP--IFSPTLFE-VEFAEEN-QPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRN 569 HSP 3 Score: 97.0561 bits (240), Expect = 5.034e-20 Identity = 137/600 (22.83%), Postives = 250/600 (41.67%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-VSIDGNSGT-----IILKKPLFDI-DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPA-------LFTRSNYSLSIIENKDNFSILSFA-VIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I++ DIND P+F + T V E+ +G++ A D+++ G Y L + F + + + G I+L ++ D LT++A D + ++ + + I D N++ P S Y E+ EN+P V + D D G NG+++ + Q + L +D + + ++ +DRE+++N L F + +D G S + +DV DQN+ PA L T S+ +I E+ + ++ V D+D E + + F L + SS + ++ PLD E+ Y+ I V+ N +S ++ V V D NDN P + + E E N P ++ +++ D D G N+ + S + S LF I ++ + +D E + + D+G P + ++++ +LD NDN+P+++ S L+N+ +S + + V D D + ++ ++ I TG I S++ D E Y L+ D G+P R+S +TI + +N
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGG-NPPRYSSALLRVVIADANDNAPKFEKSS--------------YEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGI--------IYVKGPLDREEINN-LKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDE---GENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSG--NPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIAD---------SSTRGLFEIDPNSGEVRARSPLDREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGM--------VTVQDMDEGENAQVQLSVEPDVGKFVIQNGTGTILSSISFDREKESSYTFRLKAVDGGDPPRSSYVGVTINVLDEN 672
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh1b (protocadherin 1b [Source:ZFIN;Acc:ZDB-GENE-091015-2]) HSP 1 Score: 160.229 bits (404), Expect = 1.850e-39 Identity = 172/605 (28.43%), Postives = 265/605 (43.80%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRL-NKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI--SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + D G P SS L I I D ND PKF +Y + E+ VG +L+V A D + G G++ Y L + +SID N+G I +K + +I L V+A D+ SK V I + D N++ P+I R L + I E+ P V+ + V D+DEG+N V C + F L S N +Y L+ +D E++ I D+G P L ST L+V V D N+ +F+ + Y + E N+ +L D D+ + E + + E L + ++GE+R+ + LDRE+ YQF + ++ + + T ATV V VLD NDN P+++ SF ++EN P +G + +D D GEN+R+ +S E +G F I IL S D E + D G P + + I +N+LDENDN P P+ ++ T + V A D D ++ L + + H I GEI+L K+ G + L ++V D G P R ++A + I +
Sbjct: 212 DRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQ-SKSSKALVTITVKDQNDNAPSI------RIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVP----FQLRSASETGNDRKRKYFLQTTTLLDYERIKE-YRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEG--LFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGT--ATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLS---------VEPDNGK---FMIQNGTYTILSTI-SFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPA--NSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRIS-SEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYV 784 HSP 2 Score: 94.3597 bits (233), Expect = 3.733e-19 Identity = 137/599 (22.87%), Postives = 251/599 (41.90%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSG---TIILK---KPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES--------FHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFT----GEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I+I+D ND P+F + T + E+ VG++ A DR+SG G Y L + + F V+ D + I+L + L D L + V S S + I I D N++ P +R+ Y E+ EN+P V + D D G NG+V + Q + + L +D + + ++ S+DRE++S L F + +DNG S ++ + V DQN+ P++ R + ++ ++D + +S + A++ E + + F L S +++ + ++ LD E+ Y+ I V+ N +S ++ V V D+NDN P + + E E N P ++ ++ D D G N+ ++ S + E LF I+ ++V +D E + + + + D+G P +++V +LD NDN+P+++ L+ N+ + + V D D + R+ ++ + I T IS ++ E+ Y L+ D G+P R+S +TI + +N
Sbjct: 129 IEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSS---ALLRITITDANDNVPKF-----ERSH---------YEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGI--------IFVKGSVDREEISI-LKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIR---GIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSG--NPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSV---------PEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFM----LNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILSTISFDREKES-TYSFRLKAVDGGDPPRSSYVGITINVLDEN 682 HSP 3 Score: 63.1586 bits (152), Expect = 1.433e-9 Identity = 105/406 (25.86%), Postives = 178/406 (43.84%), Query Frame = 3
Query: 891 SIDREKV--------SNP--LNFSINCQDNGQPLLKST----IILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAV-IDQDALS--FNEFHLNSSNNFNMESFHLSSL--TQSSGE-----IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPE-WIYPSSL----DNVVNISHINIQSGTKLTRVRAIDAD--------SVSSNRLTYELKAKHDSISIDP---FTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
SIDRE + +P L F ++ D L+K T I ++++LD+N+ F+ +LSI EN ++ + V D+D+ S ++ L + E+ +L SL Q S E I +GN LDRE Y +I VV+ + S A + + + D NDNVP++ E+ EN+ + + Q+ +D D+G N ++ S + P +L L I+ VK S+D E I K + D G +K + + + D+NDN P I L D V NIS ++ GT + V D D V + + ++L++ ++ + F +L +Y + + D+GNP +S+ +L + + N
Sbjct: 87 SIDRESLKDCRNLFEGDPCFLEFEVSITD----LMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTT----GPEATNLFSLQVAQDSDEKLPQLIVLGN-LDRELRDSYDLNIKVVDGGSPPRQ--SSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSS--PVMRL-----LSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISE-DMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMN 473
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh1b (protocadherin 1b [Source:ZFIN;Acc:ZDB-GENE-091015-2]) HSP 1 Score: 159.458 bits (402), Expect = 2.252e-39 Identity = 172/605 (28.43%), Postives = 265/605 (43.80%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRL-NKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI--SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + D G P SS L I I D ND PKF +Y + E+ VG +L+V A D + G G++ Y L + +SID N+G I +K + +I L V+A D+ SK V I + D N++ P+I R L + I E+ P V+ + V D+DEG+N V C + F L S N +Y L+ +D E++ I D+G P L ST L+V V D N+ +F+ + Y + E N+ +L D D+ + E + + E L + ++GE+R+ + LDRE+ YQF + ++ + + T ATV V VLD NDN P+++ SF ++EN P +G + +D D GEN+R+ +S E +G F I IL S D E + D G P + + I +N+LDENDN P P+ ++ T + V A D D ++ L + + H I GEI+L K+ G + L ++V D G P R ++A + I +
Sbjct: 212 DRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQ-SKSSKALVTITVKDQNDNAPSI------RIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVP----FQLRSASETGNDRKRKYFLQTTTLLDYERIKE-YRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEG--LFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGT--ATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLS---------VEPDNGK---FMIQNGTYTILSTI-SFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPA--NSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRIS-SEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYV 784 HSP 2 Score: 93.9745 bits (232), Expect = 5.415e-19 Identity = 137/599 (22.87%), Postives = 251/599 (41.90%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSG---TIILK---KPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES--------FHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFT----GEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I+I+D ND P+F + T + E+ VG++ A DR+SG G Y L + + F V+ D + I+L + L D L + V S S + I I D N++ P +R+ Y E+ EN+P V + D D G NG+V + Q + + L +D + + ++ S+DRE++S L F + +DNG S ++ + V DQN+ P++ R + ++ ++D + +S + A++ E + + F L S +++ + ++ LD E+ Y+ I V+ N +S ++ V V D+NDN P + + E E N P ++ ++ D D G N+ ++ S + E LF I+ ++V +D E + + + + D+G P +++V +LD NDN+P+++ L+ N+ + + V D D + R+ ++ + I T IS ++ E+ Y L+ D G+P R+S +TI + +N
Sbjct: 129 IEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSS---ALLRITITDANDNVPKF-----ERSH---------YEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGI--------IFVKGSVDREEISI-LKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIR---GIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSG--NPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSV---------PEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFM----LNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILSTISFDREKES-TYSFRLKAVDGGDPPRSSYVGITINVLDEN 682 HSP 3 Score: 63.5438 bits (153), Expect = 1.334e-9 Identity = 105/406 (25.86%), Postives = 178/406 (43.84%), Query Frame = 3
Query: 891 SIDREKV--------SNP--LNFSINCQDNGQPLLKST----IILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAV-IDQDALS--FNEFHLNSSNNFNMESFHLSSL--TQSSGE-----IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPE-WIYPSSL----DNVVNISHINIQSGTKLTRVRAIDAD--------SVSSNRLTYELKAKHDSISIDP---FTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
SIDRE + +P L F ++ D L+K T I ++++LD+N+ F+ +LSI EN ++ + V D+D+ S ++ L + E+ +L SL Q S E I +GN LDRE Y +I VV+ + S A + + + D NDNVP++ E+ EN+ + + Q+ +D D+G N ++ S + P +L L I+ VK S+D E I K + D G +K + + + D+NDN P I L D V NIS ++ GT + V D D V + + ++L++ ++ + F +L +Y + + D+GNP +S+ +L + + N
Sbjct: 87 SIDRESLKDCRNLFEGDPCFLEFEVSITD----LMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTG----PEATNLFSLQVAQDSDEKLPQLIVLGN-LDRELRDSYDLNIKVVDGGSPPRQ--SSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSS--PVMRL-----LSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISE-DMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMN 473
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 159.458 bits (402), Expect = 2.633e-39 Identity = 172/605 (28.43%), Postives = 265/605 (43.80%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRL-NKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI--SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + D G P SS L I I D ND PKF +Y + E+ VG +L+V A D + G G++ Y L + +SID N+G I +K + +I L V+A D+ SK V I + D N++ P+I R L + I E+ P V+ + V D+DEG+N V C + F L S N +Y L+ +D E++ I D+G P L ST L+V V D N+ +F+ + Y + E N+ +L D D+ + E + + E L + ++GE+R+ + LDRE+ YQF + ++ + + T ATV V VLD NDN P+++ SF ++EN P +G + +D D GEN+R+ +S E +G F I IL S D E + D G P + + I +N+LDENDN P P+ ++ T + V A D D ++ L + + H I GEI+L K+ G + L ++V D G P R ++A + I +
Sbjct: 235 DRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQ-SKSSKALVTITVKDQNDNAPSI------RIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVP----FQLRSASETGNDRKRKYFLQTTTLLDYERIKE-YRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEG--LFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGT--ATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLS---------VEPDNGK---FMIQNGTYTILSTI-SFDREKESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPA--NSSYKFLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRIS-SEGEITLAKEFTPKHIGLHRLVVKVKDKGTPPRQTTALVHIYV 807 HSP 2 Score: 93.9745 bits (232), Expect = 5.262e-19 Identity = 137/599 (22.87%), Postives = 251/599 (41.90%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSG---TIILK---KPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES--------FHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFT----GEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I+I+D ND P+F + T + E+ VG++ A DR+SG G Y L + + F V+ D + I+L + L D L + V S S + I I D N++ P +R+ Y E+ EN+P V + D D G NG+V + Q + + L +D + + ++ S+DRE++S L F + +DNG S ++ + V DQN+ P++ R + ++ ++D + +S + A++ E + + F L S +++ + ++ LD E+ Y+ I V+ N +S ++ V V D+NDN P + + E E N P ++ ++ D D G N+ ++ S + E LF I+ ++V +D E + + + + D+G P +++V +LD NDN+P+++ L+ N+ + + V D D + R+ ++ + I T IS ++ E+ Y L+ D G+P R+S +TI + +N
Sbjct: 152 IEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSS---ALLRITITDANDNVPKF-----ERSH---------YEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGI--------IFVKGSVDREEISI-LKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIR---GIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSG--NPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSV---------PEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFM----LNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNGKFMIQNGTYTILSTISFDREKES-TYSFRLKAVDGGDPPRSSYVGITINVLDEN 705 HSP 3 Score: 62.7734 bits (151), Expect = 1.792e-9 Identity = 105/406 (25.86%), Postives = 178/406 (43.84%), Query Frame = 3
Query: 891 SIDREKV--------SNP--LNFSINCQDNGQPLLKST----IILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAV-IDQDALS--FNEFHLNSSNNFNMESFHLSSL--TQSSGE-----IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPE-WIYPSSL----DNVVNISHINIQSGTKLTRVRAIDAD--------SVSSNRLTYELKAKHDSISIDP---FTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
SIDRE + +P L F ++ D L+K T I ++++LD+N+ F+ +LSI EN ++ + V D+D+ S ++ L + E+ +L SL Q S E I +GN LDRE Y +I VV+ + S A + + + D NDNVP++ E+ EN+ + + Q+ +D D+G N ++ S + P +L L I+ VK S+D E I K + D G +K + + + D+NDN P I L D V NIS ++ GT + V D D V + + ++L++ ++ + F +L +Y + + D+GNP +S+ +L + + N
Sbjct: 110 SIDRESLKDCRNLFEGDPCFLEFEVSITD----LMKGTGPRLIEGRIEILDENDNTPQFSSPVLTLSIPENTHVGALFAIPVATDRDSGSNGIADYALTT----GPEATNLFSLQVAQDSDEKLPQLIVLGN-LDRELRDSYDLNIKVVDGGSPPRQ--SSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSS--PVMRL-----LSIDRNTGIIFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISE-DMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMN 496
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 167.162 bits (422), Expect = 1.230e-41 Identity = 169/591 (28.60%), Postives = 267/591 (45.18%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQS--GTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSA 1955
+ L + D G P SS L I I+D ND APKF Y + E+ +G +L+V A D + G +I Y + D + +D ++G I ++ P+ D+ L +V A D N K T V I I D N+++P I + + Q G I E+ P V+ + V D DEG N V C + + D+ K +Y L+ ++D E V I D+G P L ST L+V V D N+ +F++S + EN D N ++ + D D+ ++ H + + + S+ SG+IR+ LDRE+ Y F + V++ + K T A+V + VLD NDN P+++ +F + EN +G + D D GEN+ I +S E SG E + IL S D E + D G P + + + +N+LDENDN P + PS+ ++ ++ Q+ GT + VRA D D+ + L Y + + + + I GE++L K I G + L ++VTD G P R+ +A
Sbjct: 254 YDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGA-NPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQ--GG----VANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKK---KYFLQTTTALDYESVKE-YTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF--SINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGT--ASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLS---------VEPESG-EFVIQNGTGTILS-SISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSN----ISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTA 814 HSP 2 Score: 92.4337 bits (228), Expect = 2.150e-18 Identity = 142/616 (23.05%), Postives = 253/616 (41.07%), Query Frame = 3
Query: 252 PQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEF-----HLNSSNNFNMES---FHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEK--LSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
P+L Q I+I+DIND P F + T + E+ +G + A DR+SG G Y+LI + F V+ D + K+P + D LT++ D ++ + I I+D N++ P + Y E+ EN+P V + D D+G N ++ Q + ++ L +LD L + ++ IDRE V L FS+ +D G + + + + D N+ P + R ++ ++ + +S V + ++ + +N++ + F L ++ + + ++ LD E Y I V+ N +S ++ V V D+NDN P + M ENN + + ++ D D G NS++ S L P+ + S N D I +L +Q Y+F H + D+G P S+++ +LD NDN+P+++ S ++N+ +S + + V IDAD + + ++ + I TG I S++ D E Y L+ D G+P R+S +TI + +N
Sbjct: 157 PRLLDGQ---IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDE-----KQPQLIVMGMLDREQRDSYDLTIKVQDGGTP-ARASSALLRISILDTNDNAPKFEKMA--------------YEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGL--------ITVQGPIDREDVGT-LKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIR---GFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSG--NPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPD----PSARGIFSINPDSGQIRVNTVLDREQREHYDF-HVVAV-----DKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGM--------VTVIDADKGENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDEN 717 HSP 3 Score: 77.0258 bits (188), Expect = 1.160e-13 Identity = 85/376 (22.61%), Postives = 164/376 (43.62%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES---FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSF 1301
DYE + ++ ++++A D G P L S+ L + + D+ND AP F V E+ + ++++V A D +SG ++ Y ++ + F SI+ +SG I + + D ++ V A D + K VVI ++D N++ P +LNG Y + EN P V + V+D D+G+N + ++ + T I S DRE S F + D G P S + + ++VLD+N+ P + SN S + + + V +D + +N+ ++++ S F L ++ ++GE+ + + R+ ++ + V ++ + + T+
Sbjct: 473 DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF-SINPDSGQIRVNT-VLDREQREHYDFHVVAVDKGIPSLK-GTASVVITVLDRNDNDPKF-----------MLNG---YNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPES---------GEFVIQNGTGTILSSI--SFDREHQST-YTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDM----DTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTAL 815
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 167.162 bits (422), Expect = 1.377e-41 Identity = 169/591 (28.60%), Postives = 267/591 (45.18%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQS--GTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSA 1955
+ L + D G P SS L I I+D ND APKF Y + E+ +G +L+V A D + G +I Y + D + +D ++G I ++ P+ D+ L +V A D N K T V I I D N+++P I + + Q G I E+ P V+ + V D DEG N V C + + D+ K +Y L+ ++D E V I D+G P L ST L+V V D N+ +F++S + EN D N ++ + D D+ ++ H + + + S+ SG+IR+ LDRE+ Y F + V++ + K T A+V + VLD NDN P+++ +F + EN +G + D D GEN+ I +S E SG E + IL S D E + D G P + + + +N+LDENDN P + PS+ ++ ++ Q+ GT + VRA D D+ + L Y + + + + I GE++L K I G + L ++VTD G P R+ +A
Sbjct: 254 YDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGA-NPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQ--GG----VANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKK---KYFLQTTTALDYESVKE-YTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF--SINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGT--ASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLS---------VEPESG-EFVIQNGTGTILS-SISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSN----ISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTA 814 HSP 2 Score: 92.8189 bits (229), Expect = 1.978e-18 Identity = 142/616 (23.05%), Postives = 253/616 (41.07%), Query Frame = 3
Query: 252 PQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEF-----HLNSSNNFNMES---FHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEK--LSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
P+L Q I+I+DIND P F + T + E+ +G + A DR+SG G Y+LI + F V+ D + K+P + D LT++ D ++ + I I+D N++ P + Y E+ EN+P V + D D+G N ++ Q + ++ L +LD L + ++ IDRE V L FS+ +D G + + + + D N+ P + R ++ ++ + +S V + ++ + +N++ + F L ++ + + ++ LD E Y I V+ N +S ++ V V D+NDN P + M ENN + + ++ D D G NS++ S L P+ + S N D I +L +Q Y+F H + D+G P S+++ +LD NDN+P+++ S ++N+ +S + + V IDAD + + ++ + I TG I S++ D E Y L+ D G+P R+S +TI + +N
Sbjct: 157 PRLLDGQ---IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDE-----KQPQLIVMGMLDREQRDSYDLTIKVQDGGT-PARASSALLRISILDTNDNAPKFEKMA--------------YEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGL--------ITVQGPIDREDVGT-LKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIR---GFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSG--NPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPD----PSARGIFSINPDSGQIRVNTVLDREQREHYDF-HVVAV-----DKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGM--------VTVIDADKGENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDEN 717 HSP 3 Score: 77.411 bits (189), Expect = 1.062e-13 Identity = 85/376 (22.61%), Postives = 165/376 (43.88%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES---FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSF 1301
DYE + ++ ++++A D G P L S+ L + + D+ND AP F V E+ + ++++V A D +SG ++ Y ++ + F SI+ +SG I + + D ++ V A D + K + VVI ++D N++ P +LNG Y + EN P V + V+D D+G+N + ++ + T I S DRE S F + D G P S + + ++VLD+N+ P + SN S + + + V +D + +N+ ++++ S F L ++ ++GE+ + + R+ ++ + V ++ + + T+
Sbjct: 473 DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF-SINPDSGQIRVNT-VLDREQREHYDFHVVAVDKGIPSLKGTAS-VVITVLDRNDNDPKF-----------MLNG---YNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPES---------GEFVIQNGTGTILSSI--SFDREHQST-YTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDM----DTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTAL 815
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 167.548 bits (423), Expect = 1.393e-41 Identity = 169/591 (28.60%), Postives = 267/591 (45.18%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQS--GTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSA 1955
+ L + D G P SS L I I+D ND APKF Y + E+ +G +L+V A D + G +I Y + D + +D ++G I ++ P+ D+ L +V A D N K T V I I D N+++P I + + Q G I E+ P V+ + V D DEG N V C + + D+ K +Y L+ ++D E V I D+G P L ST L+V V D N+ +F++S + EN D N ++ + D D+ ++ H + + + S+ SG+IR+ LDRE+ Y F + V++ + K T A+V + VLD NDN P+++ +F + EN +G + D D GEN+ I +S E SG E + IL S D E + D G P + + + +N+LDENDN P + PS+ ++ ++ Q+ GT + VRA D D+ + L Y + + + + I GE++L K I G + L ++VTD G P R+ +A
Sbjct: 254 YDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGA-NPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQ--GG----VANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKK---KYFLQTTTALDYESVKE-YTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF--SINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGT--ASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLS---------VEPESG-EFVIQNGTGTILS-SISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSN----ISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTA 814 HSP 2 Score: 92.4337 bits (228), Expect = 2.500e-18 Identity = 143/613 (23.33%), Postives = 252/613 (41.11%), Query Frame = 3
Query: 252 PQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEF-----HLNSSNNFNMES---FHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEK--LSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI-NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
P+L Q I+I+DIND P F + T + E+ +G + A DR+SG G Y+LI + F V+ D + K+P + D LT++ D ++ + I I+D N++ P + Y E+ EN+P V + D D+G N ++ Q + ++ L +LD L + ++ IDRE V L FS+ +D G + + + + D N+ P + R ++ ++ + +S V + ++ + +N++ + F L ++ + + ++ LD E Y I V+ N +S ++ V V D+NDN P + M ENN + + ++ D D G NS++ S L P+ + S N D I +L +Q Y+F H + D+G P S+++ +LD NDN+P+++ N N S + N+ + + V IDAD + + ++ + I TG I S++ D E Y L+ D G+P R+S +TI + +N
Sbjct: 157 PRLLDGQ---IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDE-----KQPQLIVMGMLDREQRDSYDLTIKVQDGGTP-ARASSALLRISILDTNDNAPKFEKMA--------------YEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGL--------ITVQGPIDREDVGT-LKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIR---GFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSG--NPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPD----PSARGIFSINPDSGQIRVNTVLDREQREHYDF-HVVAV-----DKGIPSLKGTASVVITVLDRNDNDPKFML-----NGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDEN 717 HSP 3 Score: 77.411 bits (189), Expect = 9.785e-14 Identity = 74/287 (25.78%), Postives = 127/287 (44.25%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYS 1043
DYE + ++ ++++A D G P L S+ L + + D+ND AP F V E+ + ++++V A D +SG ++ Y ++ + F SI+ +SG I + + D ++ V A D + K + VVI ++D N++ P +LNG Y + EN P V + V+D D+G+N + ++ + T I S DRE S F + D G P S + + ++VLD+N+ P + SN S
Sbjct: 473 DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF-SINPDSGQIRVNT-VLDREQREHYDFHVVAVDKGIPSLKGTAS-VVITVLDRNDNDPKF-----------MLNG---YNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPES---------GEFVIQNGTGTILSSI--SFDREHQST-YTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNIS 730
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 167.162 bits (422), Expect = 1.434e-41 Identity = 169/591 (28.60%), Postives = 267/591 (45.18%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQS--GTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSA 1955
+ L + D G P SS L I I+D ND APKF Y + E+ +G +L+V A D + G +I Y + D + +D ++G I ++ P+ D+ L +V A D N K T V I I D N+++P I + + Q G I E+ P V+ + V D DEG N V C + + D+ K +Y L+ ++D E V I D+G P L ST L+V V D N+ +F++S + EN D N ++ + D D+ ++ H + + + S+ SG+IR+ LDRE+ Y F + V++ + K T A+V + VLD NDN P+++ +F + EN +G + D D GEN+ I +S E SG E + IL S D E + D G P + + + +N+LDENDN P + PS+ ++ ++ Q+ GT + VRA D D+ + L Y + + + + I GE++L K I G + L ++VTD G P R+ +A
Sbjct: 254 YDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGA-NPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQ--GG----VANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKK---KYFLQTTTALDYESVKE-YTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF--SINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGT--ASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLS---------VEPESG-EFVIQNGTGTILS-SISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSN----ISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTA 814 HSP 2 Score: 92.4337 bits (228), Expect = 2.246e-18 Identity = 142/616 (23.05%), Postives = 253/616 (41.07%), Query Frame = 3
Query: 252 PQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEF-----HLNSSNNFNMES---FHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEK--LSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
P+L Q I+I+DIND P F + T + E+ +G + A DR+SG G Y+LI + F V+ D + K+P + D LT++ D ++ + I I+D N++ P + Y E+ EN+P V + D D+G N ++ Q + ++ L +LD L + ++ IDRE V L FS+ +D G + + + + D N+ P + R ++ ++ + +S V + ++ + +N++ + F L ++ + + ++ LD E Y I V+ N +S ++ V V D+NDN P + M ENN + + ++ D D G NS++ S L P+ + S N D I +L +Q Y+F H + D+G P S+++ +LD NDN+P+++ S ++N+ +S + + V IDAD + + ++ + I TG I S++ D E Y L+ D G+P R+S +TI + +N
Sbjct: 157 PRLLDGQ---IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDE-----KQPQLIVMGMLDREQRDSYDLTIKVQDGGTP-ARASSALLRISILDTNDNAPKFEKMA--------------YEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGL--------ITVQGPIDREDVGT-LKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIR---GFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSG--NPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPD----PSARGIFSINPDSGQIRVNTVLDREQREHYDF-HVVAV-----DKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGM--------VTVIDADKGENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDEN 717 HSP 3 Score: 77.0258 bits (188), Expect = 1.239e-13 Identity = 85/376 (22.61%), Postives = 164/376 (43.62%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES---FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSF 1301
DYE + ++ ++++A D G P L S+ L + + D+ND AP F V E+ + ++++V A D +SG ++ Y ++ + F SI+ +SG I + + D ++ V A D + K VVI ++D N++ P +LNG Y + EN P V + V+D D+G+N + ++ + T I S DRE S F + D G P S + + ++VLD+N+ P + SN S + + + V +D + +N+ ++++ S F L ++ ++GE+ + + R+ ++ + V ++ + + T+
Sbjct: 473 DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF-SINPDSGQIRVNT-VLDREQREHYDFHVVAVDKGIPSLK-GTASVVITVLDRNDNDPKF-----------MLNG---YNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPES---------GEFVIQNGTGTILSSI--SFDREHQST-YTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDM----DTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTAL 815
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 167.162 bits (422), Expect = 1.534e-41 Identity = 169/591 (28.60%), Postives = 267/591 (45.18%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQS--GTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSA 1955
+ L + D G P SS L I I+D ND APKF Y + E+ +G +L+V A D + G +I Y + D + +D ++G I ++ P+ D+ L +V A D N K T V I I D N+++P I + + Q G I E+ P V+ + V D DEG N V C + + D+ K +Y L+ ++D E V I D+G P L ST L+V V D N+ +F++S + EN D N ++ + D D+ ++ H + + + S+ SG+IR+ LDRE+ Y F + V++ + K T A+V + VLD NDN P+++ +F + EN +G + D D GEN+ I +S E SG E + IL S D E + D G P + + + +N+LDENDN P + PS+ ++ ++ Q+ GT + VRA D D+ + L Y + + + + I GE++L K I G + L ++VTD G P R+ +A
Sbjct: 246 YDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGA-NPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQ--GG----VANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKK---KYFLQTTTALDYESVKE-YTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF--SINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGT--ASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLS---------VEPESG-EFVIQNGTGTILS-SISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSN----ISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTA 806 HSP 2 Score: 92.4337 bits (228), Expect = 2.669e-18 Identity = 143/613 (23.33%), Postives = 252/613 (41.11%), Query Frame = 3
Query: 252 PQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEF-----HLNSSNNFNMES---FHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEK--LSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI-NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
P+L Q I+I+DIND P F + T + E+ +G + A DR+SG G Y+LI + F V+ D + K+P + D LT++ D ++ + I I+D N++ P + Y E+ EN+P V + D D+G N ++ Q + ++ L +LD L + ++ IDRE V L FS+ +D G + + + + D N+ P + R ++ ++ + +S V + ++ + +N++ + F L ++ + + ++ LD E Y I V+ N +S ++ V V D+NDN P + M ENN + + ++ D D G NS++ S L P+ + S N D I +L +Q Y+F H + D+G P S+++ +LD NDN+P+++ N N S + N+ + + V IDAD + + ++ + I TG I S++ D E Y L+ D G+P R+S +TI + +N
Sbjct: 149 PRLLDGQ---IEIMDINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDE-----KQPQLIVMGMLDREQRDSYDLTIKVQDGGT-PARASSALLRISILDTNDNAPKFEKMA--------------YEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGL--------ITVQGPIDREDVGT-LKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEIR---GFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSG--NPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPD----PSARGIFSINPDSGQIRVNTVLDREQREHYDF-HVVAV-----DKGIPSLKGTASVVITVLDRNDNDPKFML-----NGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDEN 709 HSP 3 Score: 77.411 bits (189), Expect = 1.072e-13 Identity = 85/376 (22.61%), Postives = 165/376 (43.88%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES---FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSF 1301
DYE + ++ ++++A D G P L S+ L + + D+ND AP F V E+ + ++++V A D +SG ++ Y ++ + F SI+ +SG I + + D ++ V A D + K + VVI ++D N++ P +LNG Y + EN P V + V+D D+G+N + ++ + T I S DRE S F + D G P S + + ++VLD+N+ P + SN S + + + V +D + +N+ ++++ S F L ++ ++GE+ + + R+ ++ + V ++ + + T+
Sbjct: 465 DYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIF-SINPDSGQIRVNT-VLDREQREHYDFHVVAVDKGIPSLKGTAS-VVITVLDRNDNDPKF-----------MLNG---YNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPES---------GEFVIQNGTGTILSSI--SFDREHQST-YTFRLKAVDGGDPPRSSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDM----DTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTAL 807
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 174.481 bits (441), Expect = 5.052e-44 Identity = 174/643 (27.06%), Postives = 283/643 (44.01%), Query Frame = 3
Query: 75 DSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXX---XXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNT-YQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKL----TRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSA 1955
D+ NGV Y L+ ++ + + + +LD E + L + D G P SS L + ++D ND APKF Y + E+ +G +++V A D + G +I Y + + + +D N+G I ++ P+ D+ L +V A D K VV+ + D+N++ P I + + Q +G I E+ E V+ + V D+DEG+N V C + F L ++ +Y L+ +D EKV + I D+G P L ST L+V V+D N+ +FT+S ++ EN +++ V DA S + L S + L +++ +GEIR+ LDRE+ Y+ + + + + T ATV V VLD NDN P+++ +F + EN +G + D D GEN+R+ +S E+ +G D + + S D E + D G P + + +N+LDENDN P PS N SH + T+L ++V A D DS + LTY + + I +G I+L K+IE G + L ++V+D G P R +A
Sbjct: 174 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGA-TPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQ--DG----MANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDV----PFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVA-EVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGT--ATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLS---------VEQDNG--DFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPS------NTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 784 HSP 2 Score: 124.79 bits (312), Expect = 1.773e-28 Identity = 148/619 (23.91%), Postives = 265/619 (42.81%), Query Frame = 3
Query: 246 GQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFH-LNSSNNFNME-------SFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
G P+L Q I++ DIND P F + T + E+ +GS+ A DR++G G Y+L + F V+ D K+P + D LT++ D + + + + ++D N++ P P Y E+ EN+P V + D D+G N ++ Q ++++ L +RL++NT + ++ +DRE +S L FS+ +D G + + V V D N+ P + R + ++ ++D + +S V ++ A++ + + N + F L +++ + ++ PLD EK Y I V+ N +S ++ V V+D+NDN P Q + ++F ENN P + ++ D D G N+ + S E + LF IS E ++VK S+D E + ++ + D G P +++VN+LD NDN+P+++ S ++N+ +S + + V ID D + R+ ++ + I TG I SL+ D E Y L+ D G P R++ +TI + +N
Sbjct: 125 GSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEE-----KQPQLIVMGNLDRERWDSYDLTIKVQDGG-NPPRASSALLRVTVLDTNDNAPKFE--------------RPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRL------LRLDRNT--GLITVQGPVDREDLST-LRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIR---GIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSG--NPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAF--PENNKPGEVVAEVTASDADSGSNAELVYS---------LEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGM--------VTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDEN 687
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 174.481 bits (441), Expect = 5.052e-44 Identity = 174/643 (27.06%), Postives = 283/643 (44.01%), Query Frame = 3
Query: 75 DSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXX---XXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNT-YQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKL----TRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSA 1955
D+ NGV Y L+ ++ + + + +LD E + L + D G P SS L + ++D ND APKF Y + E+ +G +++V A D + G +I Y + + + +D N+G I ++ P+ D+ L +V A D K VV+ + D+N++ P I + + Q +G I E+ E V+ + V D+DEG+N V C + F L ++ +Y L+ +D EKV + I D+G P L ST L+V V+D N+ +FT+S ++ EN +++ V DA S + L S + L +++ +GEIR+ LDRE+ Y+ + + + + T ATV V VLD NDN P+++ +F + EN +G + D D GEN+R+ +S E+ +G D + + S D E + D G P + + +N+LDENDN P PS N SH + T+L ++V A D DS + LTY + + I +G I+L K+IE G + L ++V+D G P R +A
Sbjct: 174 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGA-TPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQ--DG----MANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDV----PFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVA-EVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGT--ATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLS---------VEQDNG--DFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPS------NTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 784 HSP 2 Score: 124.79 bits (312), Expect = 1.773e-28 Identity = 148/619 (23.91%), Postives = 265/619 (42.81%), Query Frame = 3
Query: 246 GQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFH-LNSSNNFNME-------SFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
G P+L Q I++ DIND P F + T + E+ +GS+ A DR++G G Y+L + F V+ D K+P + D LT++ D + + + + ++D N++ P P Y E+ EN+P V + D D+G N ++ Q ++++ L +RL++NT + ++ +DRE +S L FS+ +D G + + V V D N+ P + R + ++ ++D + +S V ++ A++ + + N + F L +++ + ++ PLD EK Y I V+ N +S ++ V V+D+NDN P Q + ++F ENN P + ++ D D G N+ + S E + LF IS E ++VK S+D E + ++ + D G P +++VN+LD NDN+P+++ S ++N+ +S + + V ID D + R+ ++ + I TG I SL+ D E Y L+ D G P R++ +TI + +N
Sbjct: 125 GSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEE-----KQPQLIVMGNLDRERWDSYDLTIKVQDGG-NPPRASSALLRVTVLDTNDNAPKFE--------------RPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRL------LRLDRNT--GLITVQGPVDREDLST-LRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIR---GIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSG--NPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAF--PENNKPGEVVAEVTASDADSGSNAELVYS---------LEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGM--------VTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDEN 687
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 174.096 bits (440), Expect = 6.451e-44 Identity = 174/643 (27.06%), Postives = 283/643 (44.01%), Query Frame = 3
Query: 75 DSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXX---XXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNT-YQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKL----TRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSA 1955
D+ NGV Y L+ ++ + + + +LD E + L + D G P SS L + ++D ND APKF Y + E+ +G +++V A D + G +I Y + + + +D N+G I ++ P+ D+ L +V A D K VV+ + D+N++ P I + + Q +G I E+ E V+ + V D+DEG+N V C + F L ++ +Y L+ +D EKV + I D+G P L ST L+V V+D N+ +FT+S ++ EN +++ V DA S + L S + L +++ +GEIR+ LDRE+ Y+ + + + + T ATV V VLD NDN P+++ +F + EN +G + D D GEN+R+ +S E+ +G D + + S D E + D G P + + +N+LDENDN P PS N SH + T+L ++V A D DS + LTY + + I +G I+L K+IE G + L ++V+D G P R +A
Sbjct: 35 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGA-TPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQ--DG----MANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG----DVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVA-EVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGT--ATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLS---------VEQDNG--DFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPS------NTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 645 HSP 2 Score: 115.546 bits (288), Expect = 1.409e-25 Identity = 141/601 (23.46%), Postives = 255/601 (42.43%), Query Frame = 3
Query: 300 NDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFH-LNSSNNFNME-------SFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
ND P F + T + E+ +GS+ A DR++G G Y+L + F V+ D K+P + D LT++ D + + + + ++D N++ P P Y E+ EN+P V + D D+G N ++ Q ++++ L +RL++NT + ++ +DRE +S L FS+ +D G + + V V D N+ P + R + ++ ++D + +S V ++ A++ + + N + F L +++ + ++ PLD EK Y I V+ N +S ++ V V+D+NDN P Q + ++F ENN P + ++ D D G N+ + S E + LF IS E ++VK S+D E + ++ + D G P +++VN+LD NDN+P+++ S ++N+ +S + + V ID D + R+ ++ + I TG I SL+ D E Y L+ D G P R++ +TI + +N
Sbjct: 1 NDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEE-----KQPQLIVMGNLDRERWDSYDLTIKVQDGG-NPPRASSALLRVTVLDTNDNAPKFE--------------RPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRL------LRLDRNT--GLITVQGPVDREDLST-LRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIR---GIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSG--NPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAF--PENNKPGEVVAEVTASDADSGSNAELVYS---------LEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGM--------VTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDEN 548
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh9 (protocadherin 9 [Source:MGI Symbol;Acc:MGI:1306801]) HSP 1 Score: 147.902 bits (372), Expect = 8.603e-36 Identity = 155/592 (26.18%), Postives = 273/592 (46.11%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS-FVSIDGNSGTIILKKPLFDIDKLTL---TVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKD---IEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E+ VG+ ++++HA D + G +I Y +T +++ +G I +++ L D ++ + TV A D + ++ V I + DVN++ PNI D R +NG +Y + E +P N +++ I V DKD NG V C I+ + F+L K Y QY L +D E +F I D+G+P L T +++V + D+N+ P +F + LS+ E N+ + + + D+D+ + + L + +F L + +G + +RE+ R+ F++ A+DN S A V V VLD NDN P++ F + E N+P Y +G + D+D GEN +++S L+ NE+ +++ S D E + D+ D G P + + +N++D NDN P I P S + + ++ G+ + V A+D D+ + L Y + + ++ IDP TG I+L + + G + L + ++D G P
Sbjct: 218 YVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL-DREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNI----DLRYIISPINGT-VY---LSEKDPVNTKIALITVSDKDTDVNGKVICFIER----EVPFHL-------KAVYDNQYLLETSSLLDYEGTKE-FSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASF-------FDLDRKTGVLTASRVFNREEQERFIFTV----TARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE-NLPKYSTVGVITVTDEDAGENKAVTLS-----------ILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS-NTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761 HSP 2 Score: 66.2402 bits (160), Expect = 1.689e-10 Identity = 68/275 (24.73%), Postives = 119/275 (43.27%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLF---DIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE 1010
DYE +F +++A D G+P L + + + + D ND P F V E+ G + + A D +SG I+Y+L N SF +D +G + + +F + ++ TV A D+ + V++ ++D N++ P + + + +F+ EN P+ V I V D+D G+N V I L+ + Y ++ S DRE+ S+ F + D GQP ST + ++V+D N+
Sbjct: 428 DYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPN----ASFFDLDRKTGVLTASR-VFNREEQERFIFTVTARDNGTPPLQ-SQAAVIVTVLDENDNSP------------KFTHNHFQFFVS--ENLPKYSTVGVITVTDEDAGENKAVTLSI-----------LNDNENFVLDPYSGVIKSNVSFDREQQSS-YTFDVKATDGGQPPRSSTAKVTINVMDVND 670 HSP 3 Score: 66.2402 bits (160), Expect = 1.704e-10 Identity = 132/599 (22.04%), Postives = 245/599 (40.90%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC--QIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPA------LFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
K+ I + D ND AP F + + E+ + S A D ++G G Y+L+ + F V + +G ++ + D D + ++ D K + + + DVN++RP G + + I EN P V ++ D D G N +++ Q K LF L++ L + +++S+DRE+ + ++ D ++T+ ++V D N+ P + + N ++ + E KD N I V D+D + F E + FHL ++ + + + LD E + + F I + + + T A V V + D NDN P Q V +S + ENN L + D+D G+N+ I +L N F + + +L + + E + D G P ++ ++IV +LDENDN P++ + ++ N+ + + + D D+ + +T + +++ +DP++G I +++ D E Y ++ TD G P R+S+A +TI + N
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQ-KSSTAILQVTVSDVNDNRPVFKEGQVE--------------VHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGL--------ITVQRSLDREETAI-HKVTVLASDGSSTPARATV--TINVTDVNDNPPNIDLRYIISPINGTVYLSE-KDPVNTKIALITVSDKDTDVNGKVICFIEREV---------PFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQT--ALVRVKLEDENDNPPIFNQPVIELS--VSENNRRGLYLTTISATDEDSGKNADI------------VYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH----NHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVN 669
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh9 (protocadherin 9 [Source:MGI Symbol;Acc:MGI:1306801]) HSP 1 Score: 147.517 bits (371), Expect = 1.269e-35 Identity = 155/592 (26.18%), Postives = 273/592 (46.11%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS-FVSIDGNSGTIILKKPLFDIDKLTL---TVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK---DIEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E+ VG+ ++++HA D + G +I Y +T +++ +G I +++ L D ++ + TV A D + ++ V I + DVN++ PNI D R +NG +Y + E +P N +++ I V DKD NG V C I+ + F+L K Y QY L +D E +F I D+G+P L T +++V + D+N+ P +F + LS+ E N+ + + + D+D+ + + L + +F L + +G + +RE+ R+ F++ A+DN S A V V VLD NDN P++ F + E N+P Y +G + D+D GEN +++S L+ NE+ +++ S D E + D+ D G P + + +N++D NDN P I P S + + ++ G+ + V A+D D+ + L Y + + ++ IDP TG I+L + + G + L + ++D G P
Sbjct: 95 YVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL-DREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNI----DLRYIISPINGT-VY---LSEKDPVNTKIALITVSDKDTDVNGKVICFIER----EVPFHL-------KAVYDNQYLLETSSLLDYEGTKE-FSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASF-------FDLDRKTGVLTASRVFNREEQERFIFTV----TARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE-NLPKYSTVGVITVTDEDAGENKAVTLSI-----------LNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS-NTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 638 HSP 2 Score: 68.1662 bits (165), Expect = 4.677e-11 Identity = 132/599 (22.04%), Postives = 245/599 (40.90%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC--QIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPA------LFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
K+ I + D ND AP F + + E+ + S A D ++G G Y+L+ + F V + +G ++ + D D + ++ D K + + + DVN++RP G + + I EN P V ++ D D G N +++ Q K LF L++ L + +++S+DRE+ + ++ D ++T+ ++V D N+ P + + N ++ + E KD N I V D+D + F E + FHL ++ + + + LD E + + F I + + + T A V V + D NDN P Q V +S + ENN L + D+D G+N+ I +L N F + + +L + + E + D G P ++ ++IV +LDENDN P++ + ++ N+ + + + D D+ + +T + +++ +DP++G I +++ D E Y ++ TD G P R+S+A +TI + N
Sbjct: 4 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQ-KSSTAILQVTVSDVNDNRPVFKEGQVE--------------VHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGL--------ITVQRSLDREETAI-HKVTVLASDGSSTPARATVT--INVTDVNDNPPNIDLRYIISPINGTVYLSE-KDPVNTKIALITVSDKDTDVNGKVICFIEREV---------PFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQT--ALVRVKLEDENDNPPIFNQPVIELS--VSENNRRGLYLTTISATDEDSGKNADI------------VYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH----NHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVN 546 HSP 3 Score: 67.781 bits (164), Expect = 6.917e-11 Identity = 68/275 (24.73%), Postives = 118/275 (42.91%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLF---DIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE 1010
DYE +F +++A D G+P L + + + + D ND P F V E+ G + + A D +SG I+Y+L N SF +D +G + + +F + ++ TV A D+ + V++ ++D N++ P + N + + + EN P+ V I V D+D G+N V I L+ + Y ++ S DRE+ S+ F + D GQP ST + ++V+D N+
Sbjct: 305 DYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPN----ASFFDLDRKTGVLTASR-VFNREEQERFIFTVTARDNGTPPLQ-SQAAVIVTVLDENDNSPKFT-----------HNHFQFF---VSENLPKYSTVGVITVTDEDAGENKAVTLSI-----------LNDNENFVLDPYSGVIKSNVSFDREQQSS-YTFDVKATDGGQPPRSSTAKVTINVMDVND 547
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q08174|PCDH1_HUMAN (Protocadherin-1 OS=Homo sapiens OX=9606 GN=PCDH1 PE=1 SV=2) HSP 1 Score: 171.4 bits (433), Expect = 3.161e-42 Identity = 171/643 (26.59%), Postives = 284/643 (44.17%), Query Frame = 3
Query: 75 DSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXX---XXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNT-YQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKL----TRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSA 1955
D+ NGV Y L+ ++ + + + +LD E + L + D G P SS L + ++D ND APKF +Y + E+ +G +++V A D + G +I Y + + + +D N+G I ++ P+ D+ L +V A D N K VV+ + D+N++ P I + + Q +G I E+ E V+ + V D+DEG+N V C + F L ++ +Y L+ +D EKV + I D+G P L ST L+V V+D N+ +FT+S ++ EN +++ + DA S + L S + L +++ +GEI++ LDRE+ Y+ + + + + T ATV V VLD NDN P+++ +F + EN +G + D D GEN+++ +S E+ +G D + + S D E + D G P + + +N+LDENDN P PS N SH + T+L ++V A D DS + L Y + + I +G I+L K+IE G + L ++V+D G P R +A
Sbjct: 196 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGT-NPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQ--DG----MANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDV----PFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIA-EITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGT--ATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLS---------VEQDNG--DFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPS------NTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 806 HSP 2 Score: 124.79 bits (312), Expect = 1.203e-27 Identity = 149/619 (24.07%), Postives = 265/619 (42.81%), Query Frame = 3
Query: 246 GQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPLFDI---------DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFH-LNSSNNFNME-------SFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
G P+L Q I++ DIND P F + T + E+ +GS+ A DR++G G Y+L + F V+ D K+P + D LT++ D + + + ++D N++ P P Y E+ EN+P V + D D+G N +++ Q ++++ L +RL++NT + ++ +DRE +S L FS+ +D G + + V V D N+ P + R + ++ ++D + +S V ++ A++ + + N + F L +++ + ++ PLD EK Y I V+ N +S ++ V V+D+NDN P Q V ++F ENN P + ++ D D G N+ + S E + LF IS E +QVK S+D E + ++ + D G P +++VN+LD NDN+P+++ S ++N+ +S + + V ID D + ++ ++ + I TG I SL+ D E Y L+ D G P R++ +TI + +N
Sbjct: 147 GSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEE-----KQPQLIVMGNLDRERWDSYDLTIKVQDGGSP-PRASSALLRVTVLDTNDNAPKFE--------------RPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRL------LRLDRNT--GLITVQGPVDREDLST-LRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIR---GIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSG--NPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAF--PENNKPGEVIAEITASDADSGSNAELVYS---------LEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGM--------VTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDEN 709
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q9HC56|PCDH9_HUMAN (Protocadherin-9 OS=Homo sapiens OX=9606 GN=PCDH9 PE=1 SV=2) HSP 1 Score: 148.288 bits (373), Expect = 6.192e-35 Identity = 155/592 (26.18%), Postives = 272/592 (45.95%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS-FVSIDGNSGTIILKKPLFDIDKLTL---TVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKD---IEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E+ VG+ ++++HA D + G +I Y +T +++ +G I +++ L D ++ + TV A D + ++ V I + DVN++ PNI D R +NG +Y + E +P N +++ I V DKD NG V C I+ + F+L K Y QY L +D E +F I D+G+P L T +++V + D+N+ P +F + LS+ E N+ + + + D+D+ + + L + +F L + +G + DRE+ R+ F++ A+DN S A V V VLD NDN P++ F + E N+P Y +G + D D GEN +++S L+ N++ +++ S D E + D+ D G P + + +N++D NDN P I P S + + ++ G+ + V A+D D+ + L Y + + ++ IDP TG I+L + + G + L + ++D G P
Sbjct: 218 YVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL-DREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNI----DLRYIISPINGT-VY---LSEKDPVNTKIALITVSDKDTDVNGKVICFIER----EVPFHL-------KAVYDNQYLLETSSLLDYEGTKE-FSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASF-------FDLDRKTGVLTASRVFDREEQERFIFTV----TARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE-NLPKYSTVGVITVTDADAGENKAVTLS-----------ILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS-NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761 HSP 2 Score: 74.7146 bits (182), Expect = 3.776e-12 Identity = 135/599 (22.54%), Postives = 246/599 (41.07%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC--QIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPA------LFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP---QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
K+ I + D ND AP F + + E+ + S A D ++G G Y+L+ + F V + +G ++ + D D + ++ D K + + + DVN++RP G + + I EN P V ++ D D G N +++ Q K LF L++ L + +++S+DRE+ + ++ D ++T+ ++V D N+ P + + N ++ + E KD N I V D+D + F E + FHL ++ + + + LD E + + F I + + + T A V V + D NDN P Q V +S + ENN L + D+D G+N+ I +L N F + + +L + D E + D G P ++ ++IV +LDENDN P++ + ++ N+ + + + DAD+ + +T + +D+ +DP++G I +++ D E Y ++ TD G P R+S+A +TI + N
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQ-KSSTAILQVTVSDVNDNRPVFKEGQVE--------------VHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGL--------ITVQRSLDREETAI-HKVTVLASDGSSTPARATVT--INVTDVNDNPPNIDLRYIISPINGTVYLSE-KDPVNTKIALITVSDKDTDVNGKVICFIEREV---------PFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQT--ALVRVKLEDENDNPPIFNQPVIELS--VSENNRRGLYLTTISATDEDSGKNADI------------VYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH----NHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVN 669 HSP 3 Score: 69.3218 bits (168), Expect = 1.457e-10 Identity = 71/275 (25.82%), Postives = 118/275 (42.91%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDI---DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE 1010
DYE +F +++A D G+P L + + + + D ND P F V E+ G + + A D +SG I+Y+L N SF +D +G + + +FD ++ TV A D+ + V++ ++D N++ P + N + + + EN P+ V I V D D G+N V I + F LD Y ++ S DRE+ S+ F + D GQP ST + ++V+D N+
Sbjct: 428 DYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPN----ASFFDLDRKTGVLTASR-VFDREEQERFIFTVTARDNGTPPLQ-SQAAVIVTVLDENDNSPKFT-----------HNHFQFF---VSENLPKYSTVGVITVTDADAGENKAVTLSILND---NDNFVLDP--------YSGVIKSNVSFDREQQSS-YTFDVKATDGGQPPRSSTAKVTINVMDVND 670
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|O35161|CELR1_MOUSE (Cadherin EGF LAG seven-pass G-type receptor 1 OS=Mus musculus OX=10090 GN=Celsr1 PE=1 SV=3) HSP 1 Score: 147.517 bits (371), Expect = 2.213e-34 Identity = 159/634 (25.08%), Postives = 276/634 (43.53%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFS--------INCQDNGQ-PLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFH---------------LNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSG--NEDLFWISELK---ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E VL++ A D G P+ ++ L + + D ND +P F Y + ++E+L VG +L + A D ++ + Y+L++ + ID SG ++ + + D ++ L VEA+D + + V I + D N++ P S+KR Y +++ E+ N V + D+D+G+N + I + LK FYL S + S+D V NPL+F I QD G+ PL+ S+ ++ V VLD N+ +F S + +++EN S+L +D DA ++S N + F + SSG I + LDRE+ Y F + V+ + +S A+VS+ VLD+NDN P + + +E++ N + L +D NS I T +L+G + F +S ++ + +DY+ + + D ++H + +N+ D N + P ++ SS V++S + GT + + A D D+ + R+TY L+ IDP TG I ++ + Y L + DNG P ++ + +L I+I N
Sbjct: 327 DRETKDTHVLKVSAVDHGSPRRSAATYLTVTVSDTNDHSPVFEQSEYRERIRENLEVGYEVLTIRATDGDAPSNANMRYRLLEG---AGGVFEIDARSG-VVRTRAVVDREEAAEYQLLVEANDQGRNPGPLSASATVHIVVEDENDNYPQF---SEKR-----------YVVQVPEDVAVNTAVLRVQATDRDQGQNAAIHYSIVSGN-LKGQFYLHS--------------LSGSLD---VINPLDFEAIREYTLRIKAQDGGRPPLINSSGLVSVQVLDVNDNAPIFVSSPFQAAVLENVPLGHSVLHIQAVDADAGENARLQYRLVDTASTIVGGSSVDSENPASAPDFPF-QIHNSSGWITVCAELDREEVEHYSFGVEAVDHG--SPAMSSSASVSITVLDVNDNDPMFT-QPVYELRLNEDAAVGSSVLTLRARDRDANSVI------------TYQLTGGNTRNRFALSSQSGGGLITLALPLDYKQERQYVLAVTASDG--TRSHTA-QVFINVTDANTHRP--VFQSS-HYTVSVSE-DRPVGTSIATISATDEDTGENARITYVLEDPVPQFRIDPDTGTIYTMTELDYEDQAAYTLAITAQDNGIPQKSDTTSLEILILDAN 901 HSP 2 Score: 105.531 bits (262), Expect = 1.785e-21 Identity = 142/599 (23.71%), Postives = 248/599 (41.40%), Query Frame = 3
Query: 309 APKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKL-IKNEDFSTSFVSIDGNSGTIILKKPL----FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLK---NLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQ---PLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTK---FTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFD----DKDIGENSRIS---ISSLTTTCYGP---TEKLSGNEDL-FWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPS-----SLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN----MFQS 1997
+P+F +Y V E+ G+ ++++ A D + GD G++ Y++ ++ S + ID +G + + L D L ++ H S ++ T++ + + D N+H P Y I EN +EV I D D N +++ +LL+ +F +D+R + +R R +DRE+ + + D G+ PL S + + V D+N+ F+ Y + + E+ N ++L D+D H + + F+L SL SG + + NPLD E Y I +AQD + S VSV VLD+NDN P +V N+P LG + D D GEN+R+ + + +T G +E + D F I + + V +D E + + + D G P + S+ + +LD NDN+P + P + D V S + + R R DA+SV + +LT ++S G I+L ++ + ++ + R+ +A + I + N +FQS
Sbjct: 257 SPQFPLPSYQVSVPENEPAGTAVIELRAHDPDEGDAGRLSYQMEALFDERSNGYFLIDAATGAVTTARSLDRETKDTHVLKVSAVDHGSPRRSAA---TYLTVTVSDTNDHSPVFEQSE--------------YRERIRENLEVGYEVLTIRATDGDAPSNANMR-----YRLLEGAGGVFEIDARSGV--------VRTRAVVDREEAAE-YQLLVEANDQGRNPGPLSASATV-HIVVEDENDNYPQFSEKRYVVQVPEDVAVNTAVLRVQATDRDQGQNAAIHYSIVSGNLKGQFYLHSL---SGSLDVINPLDFEAIREYTLRI----KAQDGGRPPLINSSGLVSVQVLDVNDNAPIFVSSPFQAAVLENVP---LGHSVLHIQAVDADAGENARLQYRLVDTASTIVGGSSVDSENPASAPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPAMSSSASVSITVLDVNDNDPMFTQPVYELRLNEDAAVGSSVLTL-------RARDRDANSVITYQLTGGNTRNRFALSSQSGGGLITLALPLDYKQERQYVLAVTASDGTRSHTAQVFINVTDANTHRPVFQS 806 HSP 3 Score: 104.375 bits (259), Expect = 3.766e-21 Identity = 145/629 (23.05%), Postives = 274/629 (43.56%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLV-IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDG---------------NSGTIILKKPL--FDIDKLTLTVEA--HDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMES-FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYVGRMSFE--MKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHN-KISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEIS--LTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D+E I ++ L++ A D G+P L +S LV + ++D+ND AP FV+ + V E++ +G +L + A+D ++G+ ++ Y+L+ S+D +SG I + L +++ + VEA H S +S V I ++DVN++ P + P+Y L + E+ V + D+D N + Q+ T +N F L S+ T L +Q +R+ V ++ D + T + ++V D N + +F S+Y++S+ E++ SI + + D+D N+ + +E + +G I LD E Y +I AQDN + + ++ +++LD NDN P+++ R ++ + E+ PS + Q+ D+D G N R+ + + + F+I +++ ++ +D E + + D G P + + I V++LD NDN P + D + N G+ + R+RA D D + ++ Y++ + + +D +G++ + D E + D L V P+ S A + I + QN
Sbjct: 538 DFEAIREYTLRIKAQDGGRPPLINSSGLVSVQVLDVNDNAPIFVSSPFQAAVLENVPLGHSVLHIQAVDADAGENARLQYRLVDTASTIVGGSSVDSENPASAPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPAMSSS---ASVSITVLDVNDNDPMFT--------------QPVYELRLNEDAAVGSSVLTLRARDRD--ANSVITYQL-TGGNTRNRFALSSQSGGGLITLALPLDYKQ--ERQYV-----LAVTASDGTR---SHTAQVFINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATISATDEDTGE------NARITYVLEDPVPQFRIDPDTGTIYTMTELDYEDQAAYTLAI----TAQDNGIPQKSDTTSLEILILDANDNAPRFL-RDFYQGSVFEDAPPSTSVLQVSATDRDSGPNGRLLYT---------FQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPNPLSASVGIQVSVLDINDNPPVF----EKDELELFVEENSPVGSVVARIRANDPDEGPNAQIMYQIVEGNVPEVFQLDLLSGDLRALVELDFEV-RRDYMLVVQATSAPLV-SRATVHIRLLDQN 1110 HSP 4 Score: 103.99 bits (258), Expect = 5.111e-21 Identity = 114/426 (26.76%), Postives = 183/426 (42.96%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQP-LLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP-----QYVGRMSFEMKENNIPSYELGQLIFDDKDIGEN 1445
DY+ ++VL + A D + + ++ I++ D N P F + +YT V ED VG+ I + A D ++G+ +I Y L ED F ID ++GTI L D TL + A D+ K D T + I I+D N++ P + L + Y +FE+ P + V ++ D+D G NG + Q FY++ + +R ++ +DRE V+ N D G P L +++ +QV VLD N+ P +F + L + EN S+++ D D + E F L L SG++R LD E Y + + S ATV + +LD NDN P Q + K N+ PS +G++ D D+ ++
Sbjct: 766 DYKQERQYVLAVTASDGTRSH---TAQVFINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATISATDEDTGENARITYVL---EDPVPQF-RIDPDTGTIYTMTELDYEDQAAYTLAITAQDNGI-PQKSDTTSLEILILDANDNAP------------RFLRDF--YQGSVFEDAPPSTSVLQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGV--------IRTQRRLDRENVA-VYNLWALAVDRGSPNPLSASVGIQVSVLDINDNPPVFEKDELELFVEENSPVGSVVARIRANDPDEGPNAQIMYQIVEGNVPEVFQLDLL---SGDLRALVELDFEVRRDYMLVV-----QATSAPLVSRATVHIRLLDQNDNPPELPDFQILFNNYVTNKSNSFPSGVIGRIPAHDPDLSDS 1152
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q9NYQ8|FAT2_HUMAN (Protocadherin Fat 2 OS=Homo sapiens OX=9606 GN=FAT2 PE=1 SV=2) HSP 1 Score: 146.747 bits (369), Expect = 4.127e-34 Identity = 152/602 (25.25%), Postives = 268/602 (44.52%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSK-FDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTII-LQVDVLDQNE--YPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIP-SYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL-KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELK-AKHDSISIDPFTGEISLTKDIEAGKYDLF-LQVTDNGNPMRNSSANLTI 1967
DYE ++L + D+G PQ S + L +++ D ND AP+F Y + ED VG+ I ++ D +S D G++ Y L+ T S+ +G +++ L + L VEA D + F T ++I + DVN++ P ++ L++ E+ P ++F++ D D G G+V+ +L + + R+ L L + + +D E+ + N S+ D G+PL + T+ ++V VLD NE +P F + + EN + + ++ A D D+ E + +F S+ Q +G I+ PLDRE + Y ++ V+ + +S V + V D NDN PQ + + + + P + QL D D +++ + + G F I + +L Q +D E +++ D G P + ++V ILD NDN P I+ L NV ++ S + R+ A D D + R+TY ++ + ++ SID TG +S + AG+Y++ ++ TD+G P ++S L I
Sbjct: 779 DYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLS----PTEKFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNR--------------LKVPEDLPPGTVLTFLDASDPDLGPAGEVR------YVLMDGAHGTFRVDLMTGA----LILERELDFERRAG-YNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAF---SINQDTGMIQTLAPLDREFASYYWLTVLAVDRG--SVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMG----------FFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPP--IFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSDEEAFSIDLVTGVVSSSSTFTAGEYNILTIKATDSGQPPLSASVRLHI 1334 HSP 2 Score: 98.2117 bits (243), Expect = 2.742e-19 Identity = 147/595 (24.71%), Postives = 239/595 (40.17%), Query Frame = 3
Query: 234 ACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKN---EDFSTSFVSIDGNSGTIILKKP-------LFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKL--LKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPL-LKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFN-EFHLNSSNNFNMESFHLSSLTQSSGEIRIGN--PLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQ-----YVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELK-AKHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPM 1940
A D G P S + + ++ PKF YT EDL GS I V A+ + +IY L++ E S+D ++G I ++KP L+ ID V AH ++ V I + DVN++RP K T EN P V + +DKD G++G V ++ + LF +DS + Q +D E +F + D+GQ + L S ++QV + D+N+ F Y S++EN + +++ +D D N + + + F +S Q E RI + LDRE + +Y + + KF + TV + VLD+NDN PQ Y G+ + E+ P + + ++ D D N++I+ S +GP G + L ++D E + D G + I +++ D NDN P + +PS V N T + V A D D ++ ++ Y L + SID TG I L K ++ +L ++ +D G P+
Sbjct: 2663 AQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKAVAAQD----PVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQID-----VMAH-CLQNTDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLT--------------ENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGW--------ITTLQELDCETCQT-YHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGIS---QVGDEWRISSRKTLDREHTAKYLLRV-----TASDGKFQASVTVEIFVLDVNDNSPQCSQLLYTGK----VHEDVFPGHFILKVSATDLDTDTNAQITYS-----LHGP-----GAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGG--GRSCQADITLHVEDVNDNAPRF-FPSHCAVAV---FDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPI 3196 HSP 3 Score: 97.4413 bits (241), Expect = 4.521e-19 Identity = 129/593 (21.75%), Postives = 247/593 (41.65%), Query Frame = 3
Query: 246 GQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLT--VEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKN---LFYLDSRMRLNKNTYQYKLRIRQSIDREKVS-NPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFD----DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW---IYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL--KAKHDSISIDPFTGEISLTKDIEAGKYDLF---LQVTDNGNPMRNSSANLTI 1967
G+ C+ + I + D ND P+F A YT +Q +++ S +++V A D + G + Y + ED + I+ +G + +K L ++ TL ++A D + W +V + V + ++ S+ P+Y E+ PE E+ + V ++ + ++ T N +F LD + +++R+ +D E ++ +C N + S + + + V D N+ +F Y + EN S++ ID+D + S + L ++ SG I LD E Y F + + Q + +S A V V + D NDN P++ S E + + + + E G+L+ D DI E +R TCY G + + + + ++++D E + + D F +++ + +LD NDN P+ +Y + H ++ G + +V A D D+ ++ ++TY L H+ +DP TGE++ ++ + D+F + TD G R+ A++T+
Sbjct: 2564 GRVAFCTVK---IILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYS-VNPEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPPH----WNSLVPVRLQVVPKKVSLPKFSE-----------PLYTFSAPEDLPEGSEIGIVKAV---AAQDPVIYSLVRGTTPESNKDGVFSLDPDTGV--------IKVRKPMDHESTKLYQIDVMAHCLQNTD--VVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQ-TIQLSSQALVQVSITDENDNAPRFA---SEEYRGSVVENSEPGELVATLKTLDADISEQNR------QVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKF---QASVTVEIFVLDVNDNSPQCSQLLYTGKV-------HEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHE-FKLDPHTGELTTLTALDRERKDVFNLVAKATDGGG--RSCQADITL 3101 HSP 4 Score: 93.5893 bits (231), Expect = 7.333e-18 Identity = 146/565 (25.84%), Postives = 232/565 (41.06%), Query Frame = 3
Query: 264 SSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFVSIDGNSGTIILKKPLFDID----KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVV--LDINDNVPQ-----YVGRM-------SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPK--NHNKISIIVNILDENDNEP---EWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISL 1874
++Q + I +IN P+F+ Y V +D G +L+V AID++ G +IY + ++D S S +D +SG ++ L D+ + TLTV D E K ++ V I + D N H P TQL Y + + E+ + +D D G N +V LLK +S N N + + Q +D+ + P ++ +D G P + + V + +F++S Y + I E+ S IL + + +++ N F+M S+ SG I LD EK YQ I N A +F V VVV +D NDN P +VG++ S M +NN P + D D NS + L E L F I + L + MDYE + + + ++ HD+G P +I+++ D ND+ P E IY ++ I G +L VRA D DS + Y +K + ++++I P TG IS+
Sbjct: 1430 ATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGK--SLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKL-DLGSGPSQHTLTVMVRDQ-EIPIKRNFVWVTIHVEDGNLHPPRF---------TQLH-----YEASVPDTIAPGTELLQVRAMDADRGVNAEVH-----YSLLKG----NSEGFFNINALLGIITLAQKLDQANHA-PHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSPSEVTYELREGNKDGVFSMNSY--------SGLISTQKKLDHEKISSYQLKIRGSNMA------GAFTDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFV----IHASDSDKEANSLLVYKILE------PEALK----FFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVG-------PIHPGMELLMVRASDEDS----EVNYSIKTGNADEAVTIHPVTGSISV 1927 HSP 5 Score: 90.5077 bits (223), Expect = 6.296e-17 Identity = 151/601 (25.12%), Postives = 255/601 (42.43%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED---FSTSFVSIDGNSGTIILKKPLFDID---KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNEF-HLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAK---HDSISIDPFTGEISLTKD----IEAGKYDLFLQVTDNGNPMRNS 1949
DY+ + K+ L++IA D G P L S +++++ + N P F + Y V E++ + + IL A S + ++IY +++ E F+T F +G + + PL D + K TV A D+A F V + + DVN++ P S QL +Y I E P V + D+D G+N DV QI + F+ ++N +T + + Q +D E + + + D G P L ++ V+V D N+ P F + Y ++ E +L ID D+ + +L S N + F + SSG I + N + Y + A D F + V + + N P++ + E+ EN + ++ L+ DKD G I + + +EK S N + I+ L+ L + S + I + D G + II+ DENDN P++ + + V+I N+ + + +V A DAD + +TY + + D I I+P TG + + KD +E D F++ D G P NS
Sbjct: 2132 DYQALNKYHLKVIARDGGTPSLQSEEEVLVTV--RNKSNPLFQSPYYKVRVPENITLYTPILHTQA---RSPEGLRLIYNIVEEEPLMLFTTDF-----KTGVLTVTGPL-DYESKTKHVFTVRATDTAL--GSFSEATVEVLVEDVNDNPPTFS---------QL-----VYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSKFF-----QINGSTGE--MSTVQELDYEAQQH-FHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFF----INSSSGIISMFNLCKKHLDSSYNLRV----GASDGV-FRATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLA---SEKFSINPN-GQIATLQKLDRENSTERVI----AIKVMARDGGGRVAFCTVKIILT--DENDNPPQF---KASEYTVSIQS-NVSKDSPVIQVLAYDADEGQNADVTYSVNPEDLVKDVIEINPVTGVVKV-KDSLVGLENQTLDFFIKAQDGGPPHWNS 2673 HSP 6 Score: 84.7297 bits (208), Expect = 3.331e-15 Identity = 145/617 (23.50%), Postives = 260/617 (42.14%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYF-LEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSR---MRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTI-ILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNE-DLFWISELKI-LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVS-----SNRLTYELKAKHDSISIDPF--TGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMF 1991
D E K++L++ A D G+ Q +S + I ++D+ND +P+ YT V ED+ G ILKV A D ++ +I Y L +D ++G + L D L +A D + + D + + + DVN++ P +P + + +F+N V+ + D D+G N V + + + F +D+ +RL K L++R PL ++ D G P+ ST+ + V V+ +Y +F + +S+ + E+ +L A + + + + S N F L + T G + + LD E SP+Y SI ++ + + TV V + D+N++ PQ+ S + EN + + + D+D NS I+ S + GN+ F I K LQV +++D E + + + D G P H I + + D NDN P + + V S I G+K+ ++ D DS S R+T ++ D + T E L++ + Y L +Q +D+G P +S ++ + + +Q+ +
Sbjct: 2973 DREHTAKYLLRVTASD-GKFQ--ASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSL---HGPGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGGRSCQAD---ITLHVEDVNDNAPRF---------------FPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSA--EGHFSIDATTGVIRLEK-----PLQVRPQA-------PLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRVVSGNE--QGRFRLDART---GILYVNASLDFETSPKYFLSIECSRKSS--SSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYS-----------LIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPI----GSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAE-GLSRRAQE-WYQLQIQASDSGIPPLSSLTSVRVHVTEQSHY 3527 HSP 7 Score: 78.1814 bits (191), Expect = 3.457e-13 Identity = 98/398 (24.62%), Postives = 166/398 (41.71%), Query Frame = 3
Query: 651 DKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTK--LLKNLF----YLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSF--ATVSVVVLDINDNVPQYVGRMSFEMKENNIPS-YELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTY 1814
D RT ++ G +E +NP F+ + +D + GDV Q+ T L N + + + Y + +++ D + + N + + +D G P L+S + V V +N+ LF Y + + EN ++ ++ A S L N E L + +G + + PLD E ++ F++ + T SF ATV V+V D+NDN P + + +P+ + QL+ D+D G N +S Y E S F I + Q +DYE + + + D+G P + ++VN+ D NDN PE+ P NV ++ G + +V+AID DS ++RL Y
Sbjct: 2044 DNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYTYFRIDPYLGDISLKKPFDYQAL-NKYHLKVIARDGGTPSLQSEEEVLVTV--RNKSNPLFQSPYYKVRVPENITLYT----PILHTQARSPEGLRL-IYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATD-----TALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVS--------YQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELA----TCGHLVLKVQAIDPDSRDTSRLEY 2416 HSP 8 Score: 75.8702 bits (185), Expect = 2.023e-12 Identity = 119/480 (24.79%), Postives = 201/480 (41.88%), Query Frame = 3
Query: 588 THVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKS---TIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNP---LDREKSPRYQFSIFVVNEAQDNTKFTSFATVSV-VVLDINDNVP-----------------QYVGRMSFEMKE---NNIPSYELGQLI--FDDK-----DIGE----NSRISISSLTTTCYGPTEKL-----SGNEDLFWISELK--ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIE 1889
T VVI I+D NNH P + S Y + EN P V + D+D G+NG V I K L F +D + + + + +D E + F + D G P + +I LQ+ L+ N+ +F N + SI ++ SI++ + ID D L ++ + S N +E F L+ SG I + P L + Y I A D + S T+++ VV D + VP ++G + E + ++ +Y++ F+D D+ E N+ ++ + T G KL GNE+ + EL+ +L V +DYE + +++ +D G P+ + + VN+ D NDN P + P + IS + + GT + + DADS + R+ Y L + + S+ P TGE+ +T ++
Sbjct: 442 TVVVIDIVDCNNHAPLFNRSS--------------YDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKALP--FSIDPYLGI--------ISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQ--PMFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQNLKYEIVSGNE--LEYFDLNHF---SGVISLKRPFINLTAGQPTSYSLKI----TASDGKNYASPTTLNITVVKDPHFEVPVTCDKTGVLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFP-PGGYQ--LTISE-DTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEKFSLHPLTGELVVTGHLD 882 HSP 9 Score: 69.3218 bits (168), Expect = 2.164e-10 Identity = 121/585 (20.68%), Postives = 249/585 (42.56%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDII--DINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDIDK-LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL-KILQVKQSMDYEFIHNCKID--IHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLF 1910
DYE K V + A D L S + ++++ D+ND P F YT + E L + ++++ A D++SG + Y+++++ + F I+G++G + + L ++ + + V A D + + T VV+ + D+N++ P P Y + E V + +D D ++ I + ++ F +N ++ + ++ ++ + + N + D + ++T+ + ++ + N+Y F + Y + EN ++ ID+D+ + N E F ++ +G+I LDRE S +I V+ A+D +F TV +++ D NDN PQ+ + ++ N + Q++ D D G+N+ ++ S P + + +D+ I+ + +++VK S+ + N +D I D G P ++ + + + ++ + + P++ P S+ +++ S I I + V A D S R T K S+DP TG I + K ++ L+
Sbjct: 2232 DYESKTKHVFTVRATDTA---LGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGE-TLVVVNVSDINDNPPEFR--------------QPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFF-------INSSSGIISMF---NLCKKHLDSSYNLRVGASDG---VFRATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFSINP----NGQIATLQKLDRENSTERVIAIKVM--ARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYS------VNPEDLV---KDVIEINPVTGVVKVKDSL--VGLENQTLDFFIKAQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGI-----VKAVAAQDPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLY 2763 HSP 10 Score: 67.781 bits (164), Expect = 5.479e-10 Identity = 146/613 (23.82%), Postives = 245/613 (39.97%), Query Frame = 3
Query: 222 LQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRP----NISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQV--DVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNP----LDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLF-WISELKILQVKQ-SMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTK--DIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN--MFQS 1997
L + A D G PQ ++I + + AP F Y + E + VGS IL V A+ ++ Y+L E S++ SG I +K L D +K++ L + + A F VV+ IID N++ P + VG Q+ P+Y + I + N F I+ D D+ N + +I + LK F +D M L I +D E + + F + D G P+L + QV V D N+ P F+ Y ++I+ +L D+D S + + + N + H +G I + NP L R+ + R ++ QD A V + + + D Q+ + + + N+ + +I + N +S L T D+F + +LQ + + D E ++ + D P+ + + V+I D NDN P++ + I + G L +V A D D ++ +TYE + IDP+ G+ISL K D +A KY L + D G P S + + + ++ +FQS
Sbjct: 1628 LTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSPS-----EVTYEL--REGNKDGVFSMNSYSGLISTQKKL-DHEKISSYQLKIRGSNMA---GAFTDVMVVVDIIDENDNAPMFLKSTFVG-------QISEAAPLYSM-IMDKNNNPF---VIHASDSDKEANSLLVYKILEPEALK-FFKIDPSMG--------TLTIVSEMDYESMPS-FQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDED--SEVNYSIKTGNADEAVTIH-----PVTGSISVLNPAFLGLSRKLTIRASDGLY-----QDT------ALVKISLTQVLDKSLQFDQDVYWAAVKENLQDRK-ALVILGAQGNHLNDTLSYFLLNGT------------DMFHMVQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLP----YYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYTYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQS 2173
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q9H251|CAD23_HUMAN (Cadherin-23 OS=Homo sapiens OX=9606 GN=CDH23 PE=1 SV=2) HSP 1 Score: 145.206 bits (365), Expect = 1.154e-33 Identity = 156/618 (25.24%), Postives = 279/618 (45.15%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FD-IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNF-SINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES--FHLSSLTQ-----SSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSF-EMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMD-YEFIHNCKIDIHFHDEGFP--KNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI--NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSIS--IDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
DYE + ++ L A + P K+ I +I+ ND P F Y + E++ VG+ +L V A D ++G FG++ Y + D S+D ++G I+L L ++ I + TLT+ A D + V I ++DVN++ P + Y + EN P ++ + D+D N + I + + Y D + + + + +D E++SN L + ++ D G P L ST+ + ++V D+N+ P F++ Y +S++EN I++ A + L N L+ S + ES + L TQ SGEI + LDRE Y + V+ + + T ATV++ +LDINDN P + + + E P ++ ++ D D+GEN +L + P + S N I + +++ D +E KI + D G P K + ++ VN+LD NDN+P + N+ ++ + I +G + +V AID D + ++Y + + I+ +G + T +++ +Y L + +D G P ++S++ LTI + N
Sbjct: 420 DYETVDRYDFDLFANE-SVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDR----FSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETT---GRVRINVLDVNDNVPTFQKDA--------------YVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGS--YFDISLYEGYGV----ISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVEN-----IMAGATV----LFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGEN-----GTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDP------TFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVN 989 HSP 2 Score: 118.242 bits (295), Expect = 1.932e-25 Identity = 140/598 (23.41%), Postives = 261/598 (43.65%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQ-PQLCSSQK--LVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVIL----KVHAIDRESGDFGKIIYKLIKNE----DFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFNEFHL------NSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQD---NTKFTSFATVSVVVLDINDNVPQYVG-RMSFEMK---ENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFL 1913
D E IP++ L + D + P++ L+I + D ND P F Y V E+ G+ + + A+D + + + Y+L+ + D ++S + SG +I+ + F L L + A D NS H++I I+D N++RP S + + + EN P F V + D+D G NG++ +I+ + L +L + + N +IDRE+ + ++ D G L T I+ + + D N+ F ++S++E+ + ++++ ID D E+H+ + ++ ++ ++G + + +P++RE Y+ ++ V++ A D + A ++V VLD+NDN PQ+ +++ M+ E P L + D D G N ++ + L G + ED S + +++DYE +H + D G P +I + + I+D NDN P + PS + V ++ GT + V A DADS + + Y L +I+P TG+I + ++ K D ++
Sbjct: 1915 DRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSG-VIIDREAFSPPILELLLLAEDIGLLNST---AHLLITILDDNDNRPTFSPAT--------------LTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHLVTGVIRVGNA---------TIDREEQES-YRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQL----ED----SSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFE----DVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDHYI 2472 HSP 3 Score: 115.161 bits (287), Expect = 1.967e-24 Identity = 151/625 (24.16%), Postives = 270/625 (43.20%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHN--SKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFIN----VVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNP-LNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMES-------FHLSSLTQSSGEIRIGNP-LDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGN-EDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISI-----IVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGK--------------YDLFLQVTDNGNPMRNS 1949
D E I + L + A D G P L S+ + I ++DIND P + + E+ V S + V A D +SG ++ + + F I+ +G + + +PL I + LT+ D+ E+ ++ D+ ++IF+ D N++ P + K T Y E+ EN+P ++ +N +D D+ V Q+ + LF +N +T +R IDRE S P L + +D G LL ST L + +LD N+ F+ + ++ ++EN FS+L D+D+ LN + +E+ HL +G IR+GN +DRE+ Y+ ++ + + A V++++ DIND+ P+++ + + + E+ P + + D D+ N ++ + T++L N ED F ++ + VK M+ E + ++ + D +S+ VN+LD NDN P++ P + + GT L V A+D D + +TY L + + P G + L +D AGK + ++ +DNG+P R +
Sbjct: 1810 DRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFF--INATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFT----KST----------YQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQ--SGLF------DINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIG--LLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDS------GLNGELVYRIEAGAQDRFLIHL-----VTGVIRVGNATIDREEQESYRLTVVATDRG--TVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDL--NPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQF-KPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTL------LDLVP-PGYVQL-EDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAA 2384 HSP 4 Score: 114.775 bits (286), Expect = 2.197e-24 Identity = 154/608 (25.33%), Postives = 257/608 (42.27%), Query Frame = 3
Query: 255 QLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQT--TKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPL---NFSINCQ-----DNGQPLLKS-TIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSI-LSFAVIDQDA-LSFN---EFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELK-----AKHDSISIDPFTGEISLTK-----DIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
Q ++K+ I + D+ND AP F + Y+ + E+ VG+ I V+A D + G G ++Y + F +ID G + + + L LTV A D + ++ I I DV + P + P Y I+E++P V I +D+D+G+ + I + T + L Y+ + LN +DRE NPL F + + D+ P + T + V+D N+ F S YS++I E + F++ L V+D+D L N E +L +N+ + S ++ IR+ PLD E RY F +F D+ +A V + +++ NDN P + + + + EN + ++ D D G +S S + D F + + ++ + +DYE I + I D G + ++ I N+LD NDN P + D V N S T+L R+RA D DS +N++TY + + IS+ G IS+++ I G L + D GNP NS+ +TI ++ +N
Sbjct: 111 QGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQP----PSQFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDP-------------IFINLP-YSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNG-----------LLDRE---NPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDH---VGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYF------------FSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRI--NVLDVNDNVPTF----QKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 665 HSP 5 Score: 112.079 bits (279), Expect = 1.486e-23 Identity = 151/597 (25.29%), Postives = 274/597 (45.90%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKV-VQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF--VSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPI-YFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD--NFSILSFAVIDQD-----ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKS-PRYQFSIFVVNEAQD-NTKFTSFATVSVVVLDINDNVPQYVG--RMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQ--SMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDIEAGK---YDLFLQVTDN 1928
+ L ++A D G P++ S+ K+ I ++D ND +P+F + + V + ED VG + V A D ++G G++++ L + + +F V+ + + G + + +PL ++D L V A D K D H++ + I+D+N++ P I P Y + + EN V + D+D G N + I T+ K++ + R+++ + + R DRE+ S + +D G P L +T + V ++D+N+ +F + +Y + + E D N S+++ +D D +++ N N F ++ H+ G I LD E S RY + ++ + + TS TV V V DINDNVP + FE+ E P + + D+D G N ++ S + G F IS ++ +L+V++ +D E I + I D G P + + + + +LD NDN+P + +L + IS N + + V A DADS + RLT+ + A + + I+ TG +++ + ++ + Y L + V DN
Sbjct: 1385 YTLTVVADD-GGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASG-NIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKD--HILQVTILDINDNPPVIE--------------SPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYI--TEGNKDMAF-----RMDRISGEIATRPAPP-DRERQSF-YHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDR-HM-------GVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQ-PGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGE----------FVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLL---NLPMNITISE-NSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDN 1931 HSP 6 Score: 105.145 bits (261), Expect = 2.131e-21 Identity = 108/399 (27.07%), Postives = 177/399 (44.36%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDS---AEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-----FAVIDQDAL--SFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV 1355
DYE + + A D G P + + ++I+DIND P F +Y + V ED+ VG++IL V A D +SG+F I Y L E S +I+ +G I + L D LT A D+ N + + VVI ++DVN+ RP S P + ++EN P V + D+DEG NG++ ++ + F++D M T Q L QS ++ + ++ D G+P L T +L V+V+D N+ +F R +I+ ++ + S +A + L + L ++ N + E F + + SG I+ LDRE Y I V ++ + + + V + DI+DN P +V
Sbjct: 2361 DYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGE----SKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFS--------------KPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGV--EAFHVD--MDSGLVTTQRPL---QSYEK------FSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNG-TILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPI---SGLIQTAQRLDRESQAVYSL-ILVASDLGQPVPYETMQPLQVALEDIDDNEPLFV 2723 HSP 7 Score: 101.679 bits (252), Expect = 2.331e-20 Identity = 141/635 (22.20%), Postives = 262/635 (41.26%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQ--PQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDIDK---LTLTVEA--HDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-----------QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMES-FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQD-NTKFTSFATVSVVVLDINDNVPQ--YVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSIS--IDPFTGEISLTKDIEAGK-----YDLFLQVTDNGNPMRNSSANLTIIIYQQN----MFQ 1994
D E ++L L A D G + + + + ++D+ND P F+ +Y V ED+ G IL++ A D + G+FG++ Y+++ + + + S ++++ P D ++ L VEA HD S V++++ D+N+ P + R L + E V + D+D G G V +I ++T L+ + YLD K +Y +++ D P + + + +L++ + F+ ++Y +I+EN I+ D L+ + N+ + ++ F + ++T G I + +DREK Y ++ A D K S V + VLD NDN P+ + + + E+ + + D D G N ++ S + G E ++ N+ + + V + +D E + + + + D G P + V ILD NDN P P + VN N+ GT + +VRA D D ++ L+Y + + ++ +D +GEI+ T+ + Y L V D G P +++ ++ + I +N MFQ
Sbjct: 1059 DRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHV---SNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSS---VRVIVYVEDINDEAPVFTQQQYSR-------------LGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFEIDESTGLIITVNYLDYE---TKTSYM-------------------MNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDAIT---GVITVQGLVDREKGDFYTLTVV----ADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVF------VARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVN---ENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIA-TRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQ 1635 HSP 8 Score: 88.5817 bits (218), Expect = 2.647e-16 Identity = 123/525 (23.43%), Postives = 222/525 (42.29%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-VSIDGNSGTIILKKPLFDIDKLT-----LTVEAHDSAEHNSKFDWT-HVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDV--LDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE---FHLNSSNNFNMESFHLSSLTQSSGEIRIGNP-LDREKSPRYQFSIF------VVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSF--EMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPS 1703
DYE I +F L +IA D G + ++ ++ I+++D+ND P F Y ++E+ + ++++ A D +S +I Y ++ F + F +S+ G I + +PL D ++++ LTV A D+ N + T V I + D N++ P S P YF+ + EN V F+N D D + + I + L+ + N ++ +DRE S + + D G + T I V++ LD N+ + + Y ++++E + + + +D D L N + + N F SL ++G+IR + LDRE ++ + V + + K TS ATV V +LD+NDN P + + F E+ E + Q++ D D G N +S D S ++ +D E I ++ + D G P + ++ +++LD ND P + +P+
Sbjct: 522 DYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPL-DYEQISNGLIYLTVMAMDAG--NPPLNSTVPVTIEVFDENDNPPTFS--------------KPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESII---------YSLEGSTQFRINARSGEITTTSLLDRETKSEYI-LIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPD-LGENGTLVYSIQPPNKF-------YSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTF-QNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMP---------RMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTF-FPA 998 HSP 9 Score: 82.8037 bits (203), Expect = 1.592e-14 Identity = 145/622 (23.31%), Postives = 267/622 (42.93%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLI-KNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT-----LTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYS-LSIIENKD-NFSILSFAVIDQDA--LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIG-ENSRI---SISSLTTTCYGPTEKLSGN-EDLFWISEL-KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFT-----GEISLTKDIEAGKYDLF-LQV--TDNGNPMRNSSANLTIIIYQQN 1985
D E I ++ L+++A D G P S+ L I ++D+NDE P F Y V ED+ ++ ++ D + G ++ Y + N D S D T++ +D+ T L +EA D+ + T V + ++DVN++RP S Y + E+ PE + + D DEG+ G V +I N R+ ++ +R + +DRE+ S+ + + ++ ++S++ + V V D N+ +FT+ YS L + E S++ D+D+ + + S E + +S+G I N LD E Y ++ ++A + F +V + +L+ D Q+ SYE I ++ +G E R+ SI +L Y S + LF I + ++ V+ +D E + + D+G PK + + + + +LDENDN P + + S D+ V+I + G ++ V+A D D+ S+ ++ + L + + + + + T GE+ + + ++ + D + LQV +D G P R L + I N
Sbjct: 954 DRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVV------GLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSS--------------YEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNF-----RIHVSNGLL---MRGPRPLDRERNSSHV-LIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFE------IDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQ--GFCSVYITLLNELDEAVQFSNA-----------SYEAA--ILENLALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTV-VADDGGPKVDSTVKVYITVLDENDNSPRFDFTS--DSAVSIPE-DCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDIN 1521 HSP 10 Score: 79.7221 bits (195), Expect = 1.377e-13 Identity = 131/558 (23.48%), Postives = 233/558 (41.76%), Query Frame = 3
Query: 342 VVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINC--QDNGQPL--LKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK-DNFSILSFAVIDQD-----ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFV------VNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIF----------DDKDIGENSRISISSLTTTCY----GPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNIS-HINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVT 1922
++ ED VGS + ++ A D D +++ + E ++ F +++ ++G + L++PL K TVE S + V I + DVN++ P + P Y + I EN P + +N D D G G V Q F +DS + + + + +D E + ++N QD +PL L + I+ DV D + +F YS +I E+ ++ IDQD + + N+++ F ++ SG + + LDRE +P Y + +N+ + + T T +++V+DINDN P+ F E ++ EL Q+ F D+++G NS + + + PT + G D+ ++V +DYE + D+ F +E P + + + +++ENDN P + P + NIS + N+ GT + V A D D+ + ++Y D S+D TG I L ++ Y+L + T
Sbjct: 41 LISEDTPVGSSVTQLLAQDM---DNDPLVFGVSGEE--ASRFFAVEPDTGVVWLRQPLDRETKSEFTVEF--SVSDHQGVITRKVNIQVGDVNDNAPT-------------FHNQP-YSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPP---SQFFAIDSARGI--------VTVIRELDYET-TQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMD---PIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYI--------SGVLTLNGLLDRE-NPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPE------FNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPT-SVQGKADIR-------IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQP-----LYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTGLIMLIARLD---YELIQRFT 530 HSP 11 Score: 74.3294 bits (181), Expect = 5.883e-12 Identity = 149/618 (24.11%), Postives = 256/618 (41.42%), Query Frame = 3
Query: 210 PKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKD-----EGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTII-----LQVDVLDQNE-YPAL--FTRSNYSLSIIENK-DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQ----SSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVV--VLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS----ELKI--------LQVKQSMDYE----FIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH-DSISIDPFTGEISLTKDIEA-GKYDLFLQVTDNGNP 1937
P L L+A DIG L S+ L+I I+D ND P F T + E+ G +L+V A D +SG G+++Y++ E + I +G I + D ++ LTV A D T +V I I D+N+ RP + LN PI + + E+ ++ I +D D E + + T +L+ N + +N NT + ++ ++RE V+ +++ DN L + ++ L V+VLD N+ P F + Y I+E ++++ A +D D LN + + Q S+G++ +D E+ F++ A DN A + V ++DINDN P + + PSY+ + +F+D +G LT T T+ SGN L S E K + V S+D E +I + D + N + +++ +LD ND P++ P +V + N +GT + + A D D + LTY L+ ++ +D +G ++ + +++ K+ L + TD G P
Sbjct: 2035 PILELLLLAEDIGL--LNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRI---EAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRG--TVPLSGTAIVTILIDDINDSRP------------EFLN--PIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQ---EDAFAVNINTG--SVMVKSPMNRELVAT-YEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK------GLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTV----RASDNGSPPRAAEIPVYLEIVDINDNNPIF-----------DQPSYQ--EAVFEDVPVG------TIILTVTA---TDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSV----YENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVATDGGEP 2589
BLAST of Protocadherin vs. TrEMBL
Match: A0A210PLE4 (Protocadherin-9 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT12673 PE=4 SV=1) HSP 1 Score: 202.986 bits (515), Expect = 7.976e-50 Identity = 182/606 (30.03%), Postives = 285/606 (47.03%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLI--KNEDFSTSFVSIDGNSGTIILKKPLFDI--DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPF--TGEISLTKDIE--AGK-YDLFLQVTDNGNPMRNSSANLTIII 1973
D E ++ L L+A D G P + + + + D+ND AP Y VQED+ VGS IL ++A D +SG G++ Y+L + E+ F I+ SG +IL PL + + VE D + T+V+I ++D +N+ P I +G L NG I E P V+ + V+D+D G NG V C + +T +F L L+ N +Y++ + Q++DRE+V+ + ++ CQD+G P+L S VDVLD N+ P +F YS S+ E NK IL + D D E + L SN+ ++ + +G IR DRE+ + F + ++ T ATVSV V D+ND PQ++ + F+ KEN +G+L+ D D G++ R+ S + T F + I++ +D E + D G P + ++ + I DENDN P I+PS +N + IS + G+ + VRA D D + ++Y + + F TG++ L K +E AG + L + TD G+P R S L III
Sbjct: 206 DRELRERYALTLVAKDGGVPAKTADLAVHVHVTDVNDNAPMLSRTTYNFTVQEDIPVGSTILTLYATDLDSGRNGEVRYRLSPHQTEEIKNLFF-INATSGELILINPLTYVRGSSYKIIVEVGDRGQQ-PMTTQTYVIITVLDSSNNPPEIVLG-------LLTNG----VARISEYAPFGTTVAHVAVLDQDSGHNGIVMCSLDST-----IFELQV---LDVN--EYRVLVSQALDREQVAR-HSITVTCQDSGTPMLVSNANFFVDVLDVNDNPPIFLMQTYSASVKENNKVGKEILQVSATDYDEGQNAEVKYRLLHSNDTVIQ------VDTYTGMIRANAVFDRERMSSFMFKVLAIDGGSPPKSGT--ATVSVTVEDVNDEKPQFLENLFIFKRKENRQAGTIVGRLMAMDDDEGDSGRVVFSLAEESPIFSTLP-------FVVYSDGIIKTTSELDRERKKFYDFKVMASDLGRPTLSSTANVKIFIEDENDNSPNIIFPSYTNNTIVIS-VGTPPGSVVGTVRAQDPDEGLNGEVSYSFDGDNQTSYFRMFSETGDVILQKSVELFAGSVFSLNIIATDQGDPPRRSRQTLKIII 771 HSP 2 Score: 102.064 bits (253), Expect = 3.709e-18 Identity = 150/596 (25.17%), Postives = 255/596 (42.79%), Query Frame = 3
Query: 276 LVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRE-SGDFGKIIYKLIKNE-DFSTSFV-SIDGNSGTIILKKPLFDID---KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI--QTTKLLKNLFYLDSR----MRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYP---ALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI-NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFT----GEISLTKDIEAGK---YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
L++ I D+ND P F + T + E + G+ A D + S ++G Y L + FS SFV ++DG S I+ D + + LT+ A D D V + + DVN++ P +S RT+ Y + E+ P + + D D G+NG+V+ ++ T+ +KNLF++++ + +N TY +R S + D GQ + + + + VLD + P L +N I E ++ AV+DQD+ N + S + F L L + + + LDRE+ R+ SI V + S A V VLD+NDN P ++ + S +KENN E+ Q+ D D G+N+ + L N+ + + + +++ D E + + + D G P ++ V + D ND +P++ L+N+ N Q+GT + R+ A+D D S R+ + L + S PF G I T +++ + YD + +D G P +S+AN+ I I +N
Sbjct: 122 LLVYIDDVNDNYPIFDRDSQTISIPESVLPGTSYTLDGAKDADRSANYGIHNYTLYPQDLPFSVSFVKNLDGTSVVRIIVDGALDRELRERYALTLVAKDGGVPAKTADLA-VHVHVTDVNDNAPMLS-----RTT---------YNFTVQEDIPVGSTILTLYATDLDSGRNGEVRYRLSPHQTEEIKNLFFINATSGELILINPLTY-----VRGS--------SYKIIVEVGDRGQQPMTTQTYVIITVLDSSNNPPEIVLGLLTNGVARISEYAPFGTTVAHVAVLDQDS-GHNGIVMCS---LDSTIFELQVLDVNEYRVLVSQALDREQVARH--SITVTCQDSGTPMLVSNANFFVDVLDVNDNPPIFLMQTYSASVKENNKVGKEILQVSATDYDEGQNAEVKY-----------RLLHSNDTVIQVDTYTGMIRANAVFDRERMSSFMFKVLAIDGGSPPKSGTATVSVTVEDVNDEKPQF-----LENLFIFKRKENRQAGTIVGRLMAMDDDEGDSGRVVFSLAEESPIFSTLPFVVYSDGIIKTTSELDRERKKFYDFKVMASDLGRPTLSSTANVKIFIEDEN 667
BLAST of Protocadherin vs. TrEMBL
Match: A0A267GWV5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig016424g1 PE=4 SV=1) HSP 1 Score: 202.986 bits (515), Expect = 8.137e-50 Identity = 167/602 (27.74%), Postives = 283/602 (47.01%), Query Frame = 3
Query: 222 LQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFS--TSFVSIDGNSGTI-ILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSI-IENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL-KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAK-HDSISIDPFTGEISLTKDIEAGKYD----LFLQVTDNGNPMRNSSANLTIIIYQQNM 1988
+ L A D G P +S L + + D ND AP +V KN+ + E+ G +I+K+ A D ++G G+IIY L + S + NSG + + + D ++ + + V A D + + T ++I + D N++ P ISV R G P + L I EN P + +I D D G N V+C + + K F L + R +K YKL + D E + ++ C DNG P L ++ ++ V +LD+N+ P F R + L+ E + I F +D+D + L+ E +++L S+G +R DRE +Y+FS+ V + ++ A V + + D+ND+ P++ + E+KEN+ PS ++G++ D+D N ++ G+ F I +I ++D E + ++++ +D G P H + V +LDENDN P + +PS +N +N+S + + +V A D+DS + RLT+ L D I+P TGE+SL K +E G Y L ++ TD G+P + A L + + +
Sbjct: 222 MLLTAFDGGSPPKSASLNLTVRVRDENDHAPVWVTKNFRFNLTENAEGGQLIVKLEATDEDAGPNGRIIY-LFNDPRPSREAQMFYLHPNSGELQVAHGAVLDYERTSVYRIPVVARDRGVVPKQIEQT-IIIELQDYNDNVPVISV----RGLPVKPGGGP-HALSIRENQPPGQTIGYIVARDDDSGNNSHVECNLGSPGEGKIRFRLQQQQR-HKPQVVYKLITDDTFDWEATPT-VQETVWCHDNGVPRLSASQLITVVILDENDSPPTFDRQVFELAFDEEQQPGIQIHRFEAVDRDQSPTLVYSLDD------EGQRIATLGSSTGVLRSAVRFDRESCDQYRFSVHVTDGVH-----SASAEVRLTIRDVNDHAPEWHPPFTLEIKENSPPSSQVGRVNATDRDADVNGQVKF-------------FVGHNPYFAIRPTGEIFTKSNNLDRERTPSIQLNVTAYDFGQPSRHRSTIVHVTLLDENDNAPVFYFPSPANNRLNVS-CDYGPDDVVAKVIANDSDSGENGRLTFNLTGSGQDHFRINPDTGELSLAKSLECGAYQHRFALTIRATDRGSPAQTRIATLLVATTPKRL 789 HSP 2 Score: 70.4774 bits (171), Expect = 2.114e-8 Identity = 74/288 (25.69%), Postives = 121/288 (42.01%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIAC-DIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSI-------DREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALF 1025
D+E P V + + C D G P+L +SQ + + I+D ND P F + + E+ G I + A+DR+ ++Y L D ++ G+S ++ FD D+ +V D S V + I DVN+H P +P + LEI EN+P + +V +N D+D NG VK F+ + N Y + +R I DRE+ + + ++ D GQP + I+ V +LD+N+ +F
Sbjct: 445 DWEATPT-VQETVWCHDNGVPRLSASQLITVVILDENDSPPTFDRQVFELAFDEEQQPGIQIHRFEAVDRDQSP--TLVYSL----DDEGQRIATLGSSTGVLRSAVRFDRESCDQYRFSVHVTDGVHSAS----AEVRLTIRDVNDHAPEW---------------HPPFTLEIKENSPPSSQVGRVNATDRDADVNGQVK------------FF------VGHNPY-FAIRPTGEIFTKSNNLDRERTPS-IQLNVTAYDFGQPSRHRSTIVHVTLLDENDNAPVF 686
BLAST of Protocadherin vs. TrEMBL
Match: A0A1I8G4U9 (CCHC-type domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 203.371 bits (516), Expect = 2.137e-49 Identity = 164/599 (27.38%), Postives = 279/599 (46.58%), Query Frame = 3
Query: 228 LIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFS--TSFVSIDGNSGTI-ILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPI------YFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL-KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAK-HDSISIDPFTGEISLTKDIEAGKYD----LFLQVTDNGNPMRNSSANLTI 1967
L A D G P +S L + + D ND AP +V KN+ + E+ G +I+K+ A D ++G G+IIY L + S + NSG + + + D ++ + + V A D + + T ++I + D N++ P ISV G P+ + L I EN P + ++ D D G N V+C + + K F L + R +K +KL + D E + ++ C DNG P L ++ ++ V +LD+N+ P F R + L+ E + I F +D+D + L+ E +++L S+G +R DRE +Y+FS+ V + ++ A V + + D+ND+ P++ + E+KEN+ PS +G++ D+D N ++ G+ F I +I ++D E + ++++ +D G P H + V +LDENDN P + +PS +N +N+S + + +V A D+DS + RLT+ L D I+P TGE+SL K +E G Y L ++ TD G+P + A L +
Sbjct: 211 LTAFDGGSPPKSASLNLTVRVRDENDHAPVWVTKNFRFNLTENAEGGQLIVKLEATDEDAGPNGRIIY-LFNDPRPSREAQMFYLHPNSGELQVAHGAVLDYERTSVYRIPVVARDRGVVPKQIEQT-IIIELQDYNDNVPVISV-----------RGLPVKPGGGPHTLSIRENQPPGQTIGYVVARDDDSGNNSHVECNLGSPGEGKIRFRLQQQQR-HKPQVVFKLITDDTFDWEATPT-VQETVWCHDNGVPRLSASQLITVVILDENDSPPTFDRQVFELAFDEEQQPGIQIHRFEAVDRDQSPTLVYSLDD------EGQRIATLGSSTGVLRSAVRFDRESCDQYRFSVHVTDGVH-----SASAEVRLTIRDVNDHAPEWHPPFTLEIKENSPPSSHVGRVNATDRDADVNGQVKF-------------FVGHNPYFAIRPTGEIFTKSNNLDRERTPSIQLNVTAYDFGQPSRHRSTIVHVTLLDENDNAPVFYFPSPANNRLNVS-CDYGPDDVVAKVIANDSDSGENGRLTFNLTGSGQDHFRINPDTGELSLAKSLECGAYQHRFTLTIRATDRGSPAQTRIATLLV 769 HSP 2 Score: 72.4034 bits (176), Expect = 6.350e-9 Identity = 70/281 (24.91%), Postives = 116/281 (41.28%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIAC-DIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALF 1025
D+E P V + + C D G P+L +SQ + + I+D ND P F + + E+ G I + A+DR+ ++Y L D ++ G+S ++ FD D+ +V D S V + I DVN+H P +P + LEI EN+P + V +N D+D NG VK F++ ++DRE+ + + ++ D GQP + I+ V +LD+N+ +F
Sbjct: 432 DWEATPT-VQETVWCHDNGVPRLSASQLITVVILDENDSPPTFDRQVFELAFDEEQQPGIQIHRFEAVDRDQSP--TLVYSL----DDEGQRIATLGSSTGVLRSAVRFDRESCDQYRFSVHVTDGVHSAS----AEVRLTIRDVNDHAP---------------EWHPPFTLEIKENSPPSSHVGRVNATDRDADVNGQVK------------FFVGHNPYFAIRPTGEIFTKSNNLDRERTPS-IQLNVTAYDFGQPSRHRSTIVHVTLLDENDNAPVF 673
BLAST of Protocadherin vs. TrEMBL
Match: A0A210PLD8 (Protocadherin-11 X-linked OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT12667 PE=4 SV=1) HSP 1 Score: 200.29 bits (508), Expect = 6.033e-49 Identity = 179/612 (29.25%), Postives = 297/612 (48.53%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKN--EDFSTSFVSIDGNSGTIILKKPL-FDIDK-LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQ-IQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNM 1988
D E + + +IA D G+P +++I+++DIND P+F + Y V ED+AV + I V A D + G+ G++ YKL N E T F +ID +SG +I+ L ++ K T+ VEA D+A + V I ++DV+N+ P IS+ T EI EN + V+ I + D D GKNG V C + + K F + ++YK+ + Q+++RE + + +++C D G P L ++ + V V+D N+ FT+ Y +S+ ENK S++ A D D E F L+S E ++++SG I + + LDRE + FS+F ++ + T A V ++V D+NDN P+++ + ++ENN + +G L+ +DKD G NS+I+ S G F I + Q +D E + D G P N + V +LD NDN PE+++P++ +N V IS+ T ++ V D D ++R+TY +K K+ S ++ +G I L K + +A KY + D G P R + ++I++ Q +
Sbjct: 217 DRETTSSYKVNVIARDGGEPPKTGVLEVIINVLDINDNRPRFNTQMYNVTVNEDVAVNTTITTVFADDPDQGENGRVTYKLSPNQAEKIPTLF-TIDESSGDVIIVGSLIYEPGKSYTIIVEASDNALQ-PLISQSKVFIHVLDVHNNPPEISIDPLSNTEDS----------EILENAILDTAVAHITIFDPDTGKNGIVNCSVVNSDKFTLQRFAV----------HEYKVVLSQALNRE-IKDRYEVTVHCHDIGTPQLNASAMFVVHVMDINDNTPKFTQQQYFVSVQENKSLTSSVMQVAANDFDNGKNAEVMFSLDS------EGQKYFRISETSGVITVNSVLDRETVSQISFSVFAADKG--SPSLTGSAQVRMIVTDVNDNKPEFMEDTFEYNLEENNHVNINIGVLVANDKDDGNNSQITYSIHPNYHAGIP---------FAIMPNGSILATQVIDREAKARYDFTVIAEDMGNPSLRNSAHVTVFVLDVNDNNPEFVFPNAHNNTVVISY-QTPVNTIVSTVETRDIDEGMNSRVTYFMKDKNFSHIFKLNNLSGRIVLDKALTVADAKKYTFGIIAQDKGTPPRINEIAMSIVVTTQKI 787 HSP 2 Score: 98.2117 bits (243), Expect = 6.641e-17 Identity = 144/598 (24.08%), Postives = 258/598 (43.14%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIK--NEDFSTSFVS-IDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLK--NLFYLD--SRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNN-------FNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSF-EMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAK-HDSISIDPFT----GEISLTK--DIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
K+ I ++DIND +P F + T+ + E G I A D ++G+F I Y +++ + F+ + +DG I+ D + + + V A D E K V+I ++D+N++RP R +TQ+ N + + E+ N ++ + D D+G+NG V ++ + K LF +D S + + Y+ +I E N L QPL+ + + + VLD + P S+ + N ++ IL A++D F ++ N N + F L ++ + L+RE RY+ ++ + + + A V V+DINDN P++ + F ++EN + + Q+ +D D G+N+ + S S + F ISE ++ V +D E + + D+G P + + + D NDN+PE++ + N+ +H+NI G + A D D +++++TY + H I PF G I T+ D EA +YD + D GNP +SA++T+ + N
Sbjct: 133 KVSITLLDINDNSPSFSVPSITRDISEGSLTGFYIPIEAAKDADTGNF-SIQYYILEPPSSPFTVGYQEFVDGTYSVRIVLDGQLDRETTSSYKVNVIARDGGEP-PKTGVLEVIINVLDINDNRP--------RFNTQMYN------VTVNEDVAVNTTITTVFADDPDQGENGRVTYKLSPNQAEKIPTLFTIDESSGDVIIVGSLIYEPGKSYTIIVEASDNAL----------QPLISQSKVF-IHVLDVHNNPP-----EISIDPLSNTEDSEILENAILDTAVAHITIFDPDTGKNGIVNCSVVNSDKFTLQRFAVHEYKVVLSQALNREIKDRYEVTVHCHDIG--TPQLNASAMFVVHVMDINDNTPKFTQQQYFVSVQENKSLTSSVMQVAANDFDNGKNAEVMFS-----------LDSEGQKYFRISETSGVITVNSVLDRETVSQISFSVFAADKGSPSLTGSAQVRMIVTDVNDNKPEFMEDTFEYNLEENNHVNINIGVLV----ANDKDDGNNSQITYSIHPNYHAGI---PFAIMPNGSILATQVIDREAKARYDFTVIAEDMGNPSLRNSAHVTVFVLDVN 678
BLAST of Protocadherin vs. TrEMBL
Match: A0A074ZLL5 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_04911 PE=4 SV=1) HSP 1 Score: 197.208 bits (500), Expect = 8.797e-48 Identity = 182/665 (27.37%), Postives = 293/665 (44.06%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQL-CSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKN-EDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLE----IFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSN-PLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFT--RSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTS-FATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYE--LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKI-SIIVNILDENDNEPEW-----IYPS-----------------SLDNVVNISHIN----IQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISID------------------------PFTGEISLTKDI------EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + +++ACD GQP C Q L+I + D+ND P F + Y V E + GS +L VHA D +SG G + Y++ + +D +SG + KKP+ D + N VV I + DVN+H P I V + Q+ +G + F E ++EN P + I V D+D G N V+C++Q + FYL+ K Y L QS DRE + + + I C D G P K+ + + +LD NE+ F R NY++ I E ++ S + D DA ++L + E+ L + SG + LDRE +P+ +F++ ++ + S A +++ + DINDN P V + EN P + +GQLI DKD G N + L+ TE + D F ++ E L +S+D E ++ + +D G P++ N +I+V++LDENDN+PEW + P LD V + +N + G ++ ++ A DADS + LT+ L + + I+ +GE+ + + E G +++L+V+DNGNP +A L + I
Sbjct: 243 DAERKANYTGEIVACDGGQPSPKCGVQPLLIHVTDVNDNKPVFEKQVYEVTVNETVLNGSTVLTVHASDADSGSHGSVRYQIGQPVSQVVLDHFGLDASSGRLYTKKPIDAKDTALFVIPVLAKDGGNVPLIGQSVVRISVTDVNDHAPWIEVRPVQLPGKQVTSG--VKFSEGAMWVYENQPVGTNLGLIIVGDEDIGDNSLVECKLQEREY---RFYLE-HANSAKGREMYSLSTNQSFDRESLPDGSTSVQITCSDKGDPTQKTEKSIAIQILDVNEFSPEFPADRRNYNIQIEEGQNPGSFVFQAEATDLDATPMIYYYL------SREAQSLFHIDPHSGRVTTRKLLDRESTPKIRFTVHATDKNLLESDVNSTLANITITLTDINDNEPTLVENEVLRIVENR-PGFSDLVGQLIAIDKDAGLNGTVRYKLLSVL----TENNNLVNDTFMVNQESGKLFTLRSLDREQCSQYRLHVLAYDLGTPESKNTTQTIVVDVLDENDNKPEWRPMLPLLPDGQYSAQSAYSKYASRLLGLDKVFELGQLNTTAPLHRGQRVCKLAATDADSARNANLTFHLVTTYFTPEIEGDDTQRLMYHSGKATTMPNYFMVSSTSGELMIGAGLRGAGLSEPGLAEIYLRVSDNGNPPLEKTARLFVRI 890 HSP 2 Score: 81.6481 bits (200), Expect = 7.259e-12 Identity = 114/468 (24.36%), Postives = 185/468 (39.53%), Query Frame = 3
Query: 585 WTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTI-ILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP-------QYVGRM---SFEMKENNIPSYE-------LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS--------ELKILQVKQSMDYEFIHN--CKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQ------SGTKLTRVRAIDADSVSSNRLTYELKAKHDSI-SIDPFTGEISLTK 1880
W +V+I I D+N++RP +GS + T + ++ EV I D D G N ++ +L LF + N L + +D E+ +N + C D GQP K + L + V D N+ +F + Y +++ E N S +L+ D D+ S + L SSG + P+D + + F I V+ + N + V + V D+ND+ P Q G+ + E + YE LG +I D+DIG+NS + KL E F++ E+ L QS D E + + + I D+G P + SI + ILD N+ PE +P+ N NIQ G+ + + A D D ++ + Y L + S+ IDP +G ++ K
Sbjct: 150 WINVIIAIHDINDNRPYFPIGSGESTKPNVYVVSVSESVQ------PGHEVPLIGARDSDSGINAVQSYTLRGDELNPALFAVSYSPPFTLN-----LIVLDELDAERKANYTGEIVAC-DGGQPSPKCGVQPLLIHVTDVNDNKPVFEKQVYEVTVNETVLNGSTVLTVHASDADSGSHGSVRYQIGQPVSQVVLDHFGLDASSGRLYTKKPIDAKDT--ALFVIPVLAKDGGNVPLIGQSVVRISVTDVNDHAPWIEVRPVQLPGKQVTSGVKFSEGAMWVYENQPVGTNLGLIIVGDEDIGDNSLVEC------------KLQEREYRFYLEHANSAKGREMYSLSTNQSFDRESLPDGSTSVQITCSDKGDPTQKTEKSIAIQILDVNEFSPE--FPADRRN------YNIQIEEGQNPGSFVFQAEATDLD--ATPMIYYYLSREAQSLFHIDPHSGRVTTRK 581
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 179.104 bits (453), Expect = 1.955e-45 Identity = 177/615 (28.78%), Postives = 277/615 (45.04%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISV-GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPS-----------SLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + A D G P SS L + I D ND AP+F +Y V E+ VG +L+V A D + G G+I Y + + D + I+ ++G I +K PL +I V A D + K T+V I + D N++ P + + G RT + + I E+ P V+ + V DKDEG+N V C + + DS + N +Y L+ +D E++ + I D+G P L ST L+V V D N+ +F+ + + E N+ +L +D D+ + E L S + + L + SSGE+R +PLDRE RY+F + ++ + + T ATV + VLD NDN P+++ SF + EN P +G + D D GEN+++ +S E GN F + + + S D E + + D G P + + + +N+LDENDN P PS + D+VV + V A D D S+ L Y + H+ I P GEI LTK++ G + L ++V+D G P R++ A + I +
Sbjct: 238 DRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGP-SPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGV-------ANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSV---DNKKKYFLQTTTPLDYERIRD-YRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAE--LVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGT--ATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLS---------VEPDVGN---FVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPSNSSFRRLSPLAAPDSVVEV-------------VEAEDIDYGSNAELVYSIAGGNPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRHAIALVHIYV 811 HSP 2 Score: 105.531 bits (262), Expect = 1.346e-22 Identity = 135/607 (22.24%), Postives = 247/607 (40.69%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-VSIDGNSGT-----IILKKPLFDI-DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTR---------------------SNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI-LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I++ DIND P+F + T VQE+ +G+ A DR++ G + Y L + S F + + + G I+L ++ D LT+ A D S++ + + I D N++ P S Y E+ EN+P + V + D D G NG+++ I Q + + + ++ + + ++ +DRE++S+ F + +D G ST + ++V DQN+ PA+ R + +L + +KD + + F S+ N + + L + T PLD E+ Y+ I V+ N +S ++ V V D NDN P + + E E N P ++ +I D D G N+ + S + S LF I ++ + +D E + + D+G P + ++++ +LD NDN+P+++ S L+N+ +S + + V +D D + ++ ++ + + TG I S++ D E Y L+ D G P R+S +TI + +N
Sbjct: 155 IEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTP-SRYSSALLRVVITDANDNAPQFEKSS--------------YEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTGI--------ISVKGPLDREEISS-FKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKKKYFLQTTT----------PLDYERIRDYRVEIVAVDSG--NPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIAD---------SSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGM--------VTVLDMDKGENAQVQLSVEPDVGNFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDEN 708 HSP 3 Score: 105.531 bits (262), Expect = 1.429e-22 Identity = 138/560 (24.64%), Postives = 238/560 (42.50%), Query Frame = 3
Query: 390 AIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIID-VNNHRPNISVGSDKRTSTQLLN------GYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFN---EFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP----QYVGRMSFEMKENNIPS-YELGQLI----FDDKDIGENSRISISSLTTTCYG--PTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS---ISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
A D+ D G + YKL + ++ +DG +G I + ID+ TL K + + + D + N P + G R Q +N P+ L + EN + D+D +NG +K + LF L +M ++ +L + ++DRE + + + +IN D G P S+ +L+V + D N+ F +S+Y + EN +S+L D D L N E+ ++ +++ + + +S+G I + PLDRE+ ++F + ++ T++ VS+ V D NDN P + +G + NI +G + DKD GEN+ + T G P + + + LQ +DYE I + +++I D G P + S+ V + D NDN P I+ L V + N Q G K+ V A+DADS ++ L Y + A + IDP +GE+ ++ +Y+ + D G P +A + I + +N
Sbjct: 79 AADQGLPDSGHL-YKL----EVGAPYLRVDGKTGEIFTTE--IPIDRETLK-----DCRIKGKPCFLEFEVSVTDLIQNQSPRLIEG---RIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSL--QMANDRGEKLPQLIVLGNLDRE-LKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSD-LGPNGEIEYTIHQASDPVPKMLQIE---RSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTY--VSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVV-----TCVVAGDVPFQLRPAGDSSVDNKKKYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSP--IFSPPLFE-VEFAEEN-QPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRN 605
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 177.948 bits (450), Expect = 2.604e-45 Identity = 177/615 (28.78%), Postives = 277/615 (45.04%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISV-GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPS-----------SLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + A D G P SS L + I D ND AP+F +Y V E+ VG +L+V A D + G G+I Y + + D + I+ ++G I +K PL +I V A D + K T+V I + D N++ P + + G RT + + I E+ P V+ + V DKDEG+N V C + + DS + N +Y L+ +D E++ + I D+G P L ST L+V V D N+ +F+ + + E N+ +L +D D+ + E L S + + L + SSGE+R +PLDRE RY+F + ++ + + T ATV + VLD NDN P+++ SF + EN P +G + D D GEN+++ +S E GN F + + + S D E + + D G P + + + +N+LDENDN P PS + D+VV + V A D D S+ L Y + H+ I P GEI LTK++ G + L ++V+D G P R++ A + I +
Sbjct: 202 DRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTGIISVKGPLDREEISSFKFHVIARDKGP-SPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGV-------ANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSV---DNKKKYFLQTTTPLDYERIRD-YRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAE--LVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGT--ATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLS---------VEPDVGN---FVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKPSNSSFRRLSPLAAPDSVVEV-------------VEAEDIDYGSNAELVYSIAGGNPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRHAIALVHIYV 775 HSP 2 Score: 104.76 bits (260), Expect = 1.898e-22 Identity = 138/560 (24.64%), Postives = 238/560 (42.50%), Query Frame = 3
Query: 390 AIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIID-VNNHRPNISVGSDKRTSTQLLN------GYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFN---EFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP----QYVGRMSFEMKENNIPS-YELGQLI----FDDKDIGENSRISISSLTTTCYG--PTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS---ISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
A D+ D G + YKL + ++ +DG +G I + ID+ TL K + + + D + N P + G R Q +N P+ L + EN + D+D +NG +K + LF L +M ++ +L + ++DRE + + + +IN D G P S+ +L+V + D N+ F +S+Y + EN +S+L D D L N E+ ++ +++ + + +S+G I + PLDRE+ ++F + ++ T++ VS+ V D NDN P + +G + NI +G + DKD GEN+ + T G P + + + LQ +DYE I + +++I D G P + S+ V + D NDN P I+ L V + N Q G K+ V A+DADS ++ L Y + A + IDP +GE+ ++ +Y+ + D G P +A + I + +N
Sbjct: 43 AADQGLPDSGHL-YKL----EVGAPYLRVDGKTGEIFTTE--IPIDRETLK-----DCRIKGKPCFLEFEVSVTDLIQNQSPRLIEG---RIEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSL--QMANDRGEKLPQLIVLGNLDRE-LKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSD-LGPNGEIEYTIHQASDPVPKMLQIE---RSTGIISVKGPLDREEISSFKFHVIARDKGPSPKSSTTY--VSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVV-----TCVVAGDVPFQLRPAGDSSVDNKKKYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSP--IFSPPLFE-VEFAEEN-QPGEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRN 569 HSP 3 Score: 104.375 bits (259), Expect = 2.937e-22 Identity = 139/600 (23.17%), Postives = 252/600 (42.00%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-VSIDGNSGT-----IILKKPLFDI-DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPA-------LFTRSNYSLSIIENKDNFSILSFA-VIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI-LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I++ DIND P+F + T VQE+ +G+ A DR++ G + Y L + S F + + + G I+L ++ D LT+ A D S++ + + I D N++ P S Y E+ EN+P + V + D D G NG+++ I Q + + + ++ + + ++ +DRE++S+ F + +D G ST + ++V DQN+ PA L T S+ +I E+ + ++ V D+D E + + F L SS + ++ PLD E+ Y+ I V+ N +S ++ V V D NDN P + + E E N P ++ +I D D G N+ + S + S LF I ++ + +D E + + D+G P + ++++ +LD NDN+P+++ S L+N+ +S + + V +D D + ++ ++ + + TG I S++ D E Y L+ D G P R+S +TI + +N
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVQENAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTP-SRYSSALLRVVITDANDNAPQFEKSS--------------YEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTGI--------ISVKGPLDREEISS-FKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDE---GENAVVTCVVAGDVPFQLRPAGDSSVDNKKKYFLQTTTPLDYERIRDYRVEIVAVDSG--NPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIAD---------SSTRGLFEIDPSSGEVRARSPLDREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGM--------VTVLDMDKGENAQVQLSVEPDVGNFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDEN 672
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh1b (protocadherin 1b [Source:ZFIN;Acc:ZDB-GENE-091015-2]) HSP 1 Score: 164.851 bits (416), Expect = 3.782e-41 Identity = 173/602 (28.74%), Postives = 269/602 (44.68%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKL--LKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSII-ENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKL-TRVRAIDADSVSSN---RLTYELKA--KHDSISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSANLTIII 1973
+ L + D G P SS L I I D ND PKF +Y + E+ VG +L+V A D + G G++ Y + + ID N+G I +K + ++ L +V+A D+ +K V I + D N++ P+I R L + + E+ P V+ + V DKDEG+N V C + L++ DS + +Y L+ +D E++ I D+G P L ST L+V V D N+ +F+ S Y + EN+ +L V+ DA S L S + + L + ++GE+R+ N LDRE RY+F + ++ + K T ATV V VLD NDN P+++ SF + EN P +G + D D GEN+ + +S E +G F I + + S D E + D G P + + I +N+LDENDN P PS N S+ +Q T TRV +DA+ + + L Y + H I GEI+L K+ G + L ++V+D G P R+++A + I +
Sbjct: 221 YDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFERSHYEGEMAENTPVGQSVLQVKANDDDLGANGQVTYSFHQPSPNVQRLLHIDHNTGIIQVKGSVDREEVPLLKFSVQARDNGPQ-AKSSKAMVTITVKDRNDNAPSI------RIRGFGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSASASDSTSK-----RKYFLQTTTPLDYERIKE-YRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEENQPGDKVLD--VVATDADSGTNAELLYSIITDSATKGLFDINPNTGEVRVMNQLDREYKERYEFHVEAADKGVPSLKGT--ATVVVRVLDRNDNDPKFMLNGYSFSVLENMPPLSPVGMVTVIDADKGENAHVQLS---------VEPENGK---FVIQNGTGTILSSISFDREKESTYTFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPS------NSSYKFLQPLTSPDTRVEKVDAEDIDTGLNAELVYSITGGNPHGLFRISSTDGEITLAKEFTRKHNGLHRLVVKVSDKGKPSRHTTALVHIFV 787 HSP 2 Score: 100.908 bits (250), Expect = 2.962e-21 Identity = 137/600 (22.83%), Postives = 253/600 (42.17%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-VSIDGNSGTIILKKPLFD------IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIENKDNFSILS--------FAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I+I D ND P+F + + E+ VG+ A+D+++G G YKL D F + + N+ + + + D L+++ D ++ + I I D N++ P +R+ Y E+ EN P V + D D G NG V Q + ++ L ++D + ++++ S+DRE+V L FS+ +DNG S ++ + V D+N+ P++ R ++ ++D + +S A+++ E + + F L S + S ++ PLD E+ Y+ I V+ N +S ++ V V D+NDN P + + + E N P ++ ++ D D G N+ + S +T S + LF I+ ++V +D E+ + + D+G P +++V +LD NDN+P+++ S L+N+ +S + + V IDAD + + ++ ++ I TG I S++ D E Y L+ D G+P R+S +TI + +N
Sbjct: 131 IEIQDENDNTPQFPSPILELAIPENTYVGAHYSIPVAMDKDAGSNGIADYKLNSGSDAMNLFSLQVADNTDEKVPQLIVLGNLDREQRDTYDLSIKVIDGGTP-PRYSSALLRITITDTNDNVPKF-----ERSH---------YEGEMAENTPVGQSVLQVKANDDDLGANGQVTYSFHQPSPNVQRLLHIDHNTGI--------IQVKGSVDREEVPL-LKFSVQARDNGPQAKSSKAMVTITVKDRNDNAPSIRIRG---FGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSASASDSTSKRKYFLQTTTPLDYERIKEYRIEIVAVDSG--NPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEENQPGDKVLDVVATDADSGTNAELLYSIITD---------SATKGLFDINPNTGEVRVMNQLDREYKERYEFHVEAADKGVPSLKGTATVVVRVLDRNDNDPKFMLNGYSFSVLENMPPLSPVGM--------VTVIDADKGENAHVQLSVEPENGKFVIQNGTGTILSSISFDREKESTYTFRLKAVDGGDPPRSSYVGITINVLDEN 684 HSP 3 Score: 88.1965 bits (217), Expect = 2.801e-17 Identity = 76/285 (26.67%), Postives = 128/285 (44.91%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFD--IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYS 1043
DYE I ++ ++++A D G P L S+ L + + D+ND AP F Y E+ G +L V A D +SG +++Y +I + + I+ N+G + + L ++ VEA D + K T VV+ ++D N++ P +LNG Y + EN P V + V+D D+G+N V+ ++ + + + T I S DREK S F + D G P S + + ++VLD+N+ T+ + S
Sbjct: 440 DYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEENQPGDKVLDVVATDADSGTNAELLYSII-TDSATKGLFDINPNTGEVRVMNQLDREYKERYEFHVEAADKGVPSLKGTAT-VVVRVLDRNDNDPKF-----------MLNG---YSFSVLENMPPLSPVGMVTVIDADKGENAHVQLSVEPE---------NGKFVIQNGTGTILSSI--SFDREKEST-YTFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPSNS 696
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 157.918 bits (398), Expect = 6.848e-39 Identity = 158/592 (26.69%), Postives = 273/592 (46.11%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFST-SFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNL-FYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNT--KFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK---DIEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E VG+ ++++ A D + G +I Y +T +++ +G I +++PL + L+V A D + +++ V I + DVN++ PNI D R NG + + E +P N +++ I V DKD NG V C I+ K++ F+L K Y QY L +D E + F I D+G+P L T +++V + D+N+ P +FT+ L++ E NK + + + D+D+ E + L + +F L + +G + DRE R+ F++ A+DN S A V V +LD NDN P++ F + E N+P Y +G + D D GEN+ +S+S L+ NE+ +++ S D E + D+ D G P + + +N++D NDN P IYP S + + ++ G+ + V A+D D+ + L Y + ++ IDP TG I+L + + ++G + L + ++D G P
Sbjct: 217 YVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGLITVQRPLDREETANHKLSVLASDGSSSSAR---ATVTINVTDVNDNAPNI----DLRYIISPTNGTVL----LSEKDPVNTKIALITVSDKDTDVNGKVICFIE-----KDVPFHL-------KAVYDNQYLLETSALLDYEGTKEYI-FKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPNASF-------FDLDRKTGVLTASRVFDREDQERFLFTV----TARDNGTRALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSE-NLPKYSTVGVITVTDADAGENAVVSLS-----------ILNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPS-NTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVNGNNKGLFRIDPVTGNITLEEKPTEADSGLHRLVVNISDLGYP 760 HSP 2 Score: 68.5514 bits (166), Expect = 2.698e-11 Identity = 70/292 (23.97%), Postives = 125/292 (42.81%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDI---DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYP--ALFTRSNYSLSII 1055
DYE +++ +++A D G+P L + + + + D ND P F V E+ + + A D +SG +I+Y+L N SF +D +G + + +FD ++ TV A D+ + V++ I+D N++ P + N + + + EN P+ V I V D D G+N V I L+ + Y ++ S DRE+ S+ F + D+G P S + ++V+D N+ P ++ SN S ++
Sbjct: 427 DYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPN----ASFFDLDRKTGVLTASR-VFDREDQERFLFTVTARDNGTRALQ-SQAAVIVTILDQNDNSPKFT-----------HNHFQFF---VSENLPKYSTVGVITVTDADAGENAVVSLSI-----------LNDNENFILDPYTGVIKSNVSFDREQQSS-YTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPSNTSFKLV 686 HSP 3 Score: 63.929 bits (154), Expect = 6.720e-10 Identity = 125/589 (21.22%), Postives = 239/589 (40.58%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFD---IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI--QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQN----EYPALFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTI 1967
K+ I + D ND AP F + + E+ + S A D + G Y+L+ + F V + +G ++ + D D + ++ D K + + + DVN++RP K + + + I E++P V + D D G N ++K Q + + LF L+S L + +++ +DRE+ +N S+ D ++T+ + V ++ N + + + +N ++ ++ KD N I V D+D + F E + FHL ++ + + LD E + Y F I + + + T A V V + D NDN P + + + ENN L + D+D G N+ I +L N F + + +L + D E + D G ++ ++IV ILD+NDN P++ + ++ N+ + + + DAD+ + ++ + +++ +DP+TG I +++ D E Y ++ D+G+P +S+A +TI
Sbjct: 126 KIKIVVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDMGPNSVYKYELVNGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQ-KSSTAILQVTVTDVNDNRPVF-----KESQIE---------VHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGL--------ITVQRPLDREETAN-HKLSVLASDGSSSSARATVTINVTDVNDNAPNIDLRYIISPTNGTV-LLSEKDPVNTKIALITVSDKDTDVNGKVICFIEKDV---------PFHLKAVYDNQYLLETSALLDYEGTKEYIFKIVASDSGKPSLNQT--ALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEI------------VYQLGPNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGTRALQSQAAVIVTILDQNDNSPKFTH----NHFQFFVSENLPKYSTVGVITVTDADAGENAVVSLSILNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTI 662
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 157.532 bits (397), Expect = 7.802e-39 Identity = 158/592 (26.69%), Postives = 273/592 (46.11%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFST-SFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNL-FYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNT--KFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK---DIEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E VG+ ++++ A D + G +I Y +T +++ +G I +++PL + L+V A D + +++ V I + DVN++ PNI D R NG + + E +P N +++ I V DKD NG V C I+ K++ F+L K Y QY L +D E + F I D+G+P L T +++V + D+N+ P +FT+ L++ E NK + + + D+D+ E + L + +F L + +G + DRE R+ F++ A+DN S A V V +LD NDN P++ F + E N+P Y +G + D D GEN+ +S+S L+ NE+ +++ S D E + D+ D G P + + +N++D NDN P IYP S + + ++ G+ + V A+D D+ + L Y + ++ IDP TG I+L + + ++G + L + ++D G P
Sbjct: 217 YVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGLITVQRPLDREETANHKLSVLASDGSSSSAR---ATVTINVTDVNDNAPNI----DLRYIISPTNGTVL----LSEKDPVNTKIALITVSDKDTDVNGKVICFIE-----KDVPFHL-------KAVYDNQYLLETSALLDYEGTKEYI-FKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPNASF-------FDLDRKTGVLTASRVFDREDQERFLFTV----TARDNGTRALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSE-NLPKYSTVGVITVTDADAGENAVVSLS-----------ILNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPS-NTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVNGNNKGLFRIDPVTGNITLEEKPTEADSGLHRLVVNISDLGYP 760 HSP 2 Score: 68.9366 bits (167), Expect = 2.464e-11 Identity = 70/292 (23.97%), Postives = 125/292 (42.81%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDI---DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYP--ALFTRSNYSLSII 1055
DYE +++ +++A D G+P L + + + + D ND P F V E+ + + A D +SG +I+Y+L N SF +D +G + + +FD ++ TV A D+ + V++ I+D N++ P + N + + + EN P+ V I V D D G+N V I L+ + Y ++ S DRE+ S+ F + D+G P S + ++V+D N+ P ++ SN S ++
Sbjct: 427 DYEGTKEYIFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPN----ASFFDLDRKTGVLTASR-VFDREDQERFLFTVTARDNGTRALQ-SQAAVIVTILDQNDNSPKFT-----------HNHFQFF---VSENLPKYSTVGVITVTDADAGENAVVSLSI-----------LNDNENFILDPYTGVIKSNVSFDREQQSS-YTFDVRAVDSGHPPCSSAAKVTINVIDVNDNPPIVIYPPSNTSFKLV 686 HSP 3 Score: 64.3142 bits (155), Expect = 6.235e-10 Identity = 126/591 (21.32%), Postives = 243/591 (41.12%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI--QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQN----EYPALFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTI 1967
K+ I + D ND AP F + + E+ + S A D + G Y+L+ + F V + +G ++ + D ++ + + VE S + +S + + + DVN++RP K + + + I E++P V + D D G N ++K Q + + LF L+S L + +++ +DRE+ +N S+ D ++T+ + V ++ N + + + +N ++ ++ KD N I V D+D + F E + FHL ++ + + LD E + Y F I + + + T A V V + D NDN P + + + ENN L + D+D G N+ I +L N F + + +L + D E + D G ++ ++IV ILD+NDN P++ + ++ N+ + + + DAD+ + ++ + +++ +DP+TG I +++ D E Y ++ D+G+P +S+A +TI
Sbjct: 126 KIKIVVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDMGPNSVYKYELVNGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSST---AILQVTVTDVNDNRPVF-----KESQIE---------VHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGL--------ITVQRPLDREETAN-HKLSVLASDGSSSSARATVTINVTDVNDNAPNIDLRYIISPTNGTV-LLSEKDPVNTKIALITVSDKDTDVNGKVICFIEKDV---------PFHLKAVYDNQYLLETSALLDYEGTKEYIFKIVASDSGKPSLNQT--ALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEI------------VYQLGPNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGTRALQSQAAVIVTILDQNDNSPKFTH----NHFQFFVSENLPKYSTVGVITVTDADAGENAVVSLSILNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSGHPPCSSAAKVTI 662
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 146.362 bits (368), Expect = 4.569e-36 Identity = 185/682 (27.13%), Postives = 296/682 (43.40%), Query Frame = 3
Query: 33 SEAGKAFQ-NPRIRIDSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXX-----XXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS------FVSIDGNSGTIIL-------KKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEF-HLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNM 1988
+ AGK F P DS NGV Y L S + + F L+ T + + KSLD E + + L A D G P S L I++ D ND +P F + E+ VG+ ++++HA DR++G +++Y+L + + S +D NSG + + + P++ I + A D V + + DVN++ P I + R +NG IY I E + N V+ I V D D G NG V C I ++ +L K TY QY L R+++D E N I D G L T+ + + +LD N+ +FT Y +S+ EN +++ + D+D E + + M FH+ T G I + LDREK Y F+I + Q ATV V VLD+NDN P++ + F + EN +G + D D GEN R+ +S L T N LF I E +++ D E H +++ D G P + + ++++++D NDN P + P S + GT +T V A+D D+ + L Y + H+ IDP G I+L + + G + L ++V+D G +++ + L + + +
Sbjct: 166 APAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRI-----IILATDKGPEPVPAT-ATVTVTVTDVNDNSPTIEI----RDIVAPVNGV-IY---ISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEV---------PFQLKKLTYPNQYLLETRETLDYE-TKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPTM--FHMDPET---GIISLTEQLDREKKANYSFTILAKD--QGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLSILGTD----------NRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSPIVLMPPS-NTTYKFVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGNPHNLFHIDPVIGNITLMEPLTETHHGLHRLVVRVSDIGIAVQHHAVALVHVFVNETL 805
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 135.191 bits (339), Expect = 1.436e-32 Identity = 161/619 (26.01%), Postives = 268/619 (43.30%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKV-VQEDLAVGSVILKVHAIDRESGDFGKIIYKL-IKNEDFST-SFVSIDGNSGTIILKKPLFDIDKLT-----LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGY-PIYFLEIFENNPENFEVSFINVVDKDEGKNG--DVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTR--------SNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESF-HLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMS--------FEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFW--ISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLD---NVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGN 1934
D E +P + L L D G P+L S L I ++D ND AP FV V + E VG+ ++++ A D ++G G I Y K +T + + +DG +G + ++ +D+ T L V A D + + T V + + D N++ P V L Y P ++I EN P V I+V D D G +G DV+ + T L + N Q+ L+ + +D E+ N S+ D G P L + L + V+D N+ +F + Y +S+ EN + +L+ D D+ S ES L SL +G++ + PLDREK RY+ S+ + K + A V V VLD NDN P +VG + F +E ++ +Y +G + D D G+N+R++++ + GP + + G D + L +L + + YE + + D G P + + + D NDN P P++ D +V S + G +T A D D+ + R YE+ + ++ +G +SL + + + G + L ++V D G
Sbjct: 231 DREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRN-AEKLDRETMPVHRLVVVARDGGQLSRSASVT-VTVELNDDNDNAPVFEV-------IALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFPTGAELA-----------SPNKVQFLLKTTRLLDYEEAQQ-YNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRK--ARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTY-VGTVSTSDLDEGDNARVALNLVREA--GP-DWIGGAGDTPGGVVRTLVVLDREDRVQYE------LSVRAVDSGRPALSASCRVSITVSDTNDNAPVITSPNTNDTWKHVRTFSPAGMLVGVSVT---ANDIDAGDNGRPLYEIIGGNPKGIFLLNADSGALSLARTVSSLDEGLHRLVVRVRDRGG 813 HSP 2 Score: 101.293 bits (251), Expect = 5.028e-22 Identity = 121/531 (22.79%), Postives = 227/531 (42.75%), Query Frame = 3
Query: 534 TLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKN-----------GDVKCQIQTTKLLKNLFYLDSRMRLNKNT----YQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVL--DINDNVP---------QYVGRMSFEMKENNIPSYELGQLI-FDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQ----SGTKLTRVRAIDADSVSSNRLTYELK--AKHDSI----SIDPFTGEISLTKDIEAGK---YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
T+ V A + +S V + + D+N+H P P + I E+ V +D D G N GD Q+ L+++ D ++ L +R+ +DRE V + + +D G P L +++L + V+D N+ P + I E +K S++ D DA ++++ FH ++ + H+ T +R LDRE P ++ + A+D + + A+V+V V D NDN P +Y+ ++ EN +PS LI D D+G + + + T E S N+ F +L+ + +DYE + + D G PK +++I++++D NDN P ++ P+S++ V + ++++ +GT + + A DADS + +T+ L A +S+ S++ TG+++L ++ K Y+L ++ D G+P R + A + + + +N
Sbjct: 110 TVQVAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRA--------------PHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGD-GLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPS-YELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYS-FHTKLTSLATQAALHVDGTTGLV-TVRNAEKLDRETMPVHRLVVV----ARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVEN-LPSGTPVVLISVSDPDLGSSGTVDVRLEFPTG---AELASPNKVQF------LLKTTRLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDEN 608 HSP 3 Score: 69.707 bits (169), Expect = 2.507e-12 Identity = 101/470 (21.49%), Postives = 194/470 (41.28%), Query Frame = 3
Query: 687 PIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLN-FSINCQDNGQPLLKSTIILQVDVLDQNEYPALF----TRSNY----SLSIIEN-KDNFSILSFAVIDQDALSFNEFHLNSSNNFNME-----SFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFE---------MKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI----LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQS--GTKLTRVRAIDADSVSSNRLTYEL--KAKHDSISIDPFT-GEISLTKDI----EAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
P + I E++ V + D D G NG + T KL + + ++ T +R + +DRE + P++ + +D GQ +++ + V++ D N+ +F + Y + I+EN ++ +V D D L SS ++ L+S + ++ LD E++ +Y S+ + + K + + + V+DINDN P ++ S E ++EN + L+ D D G N I+ + +L+G E + + L + L + +D E ++ + D G P+ + + V +LDENDN P ++ S+ N + + ++ GT + V D D + R+ L +A D I T G + T + + +Y+L ++ D+G P ++S ++I + N
Sbjct: 276 PTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHT-KLTS--LATQAALHVDGTTGLVTVRNAEKLDRETM--PVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPD--------LGSSGTVDVRLEFPTGAELASPNKVQFLLKTTRLLDYEEAQQYNVSVLAAD--RGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFT---------LSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAGDTPGGVVRTLVVLDREDRVQYELSVRAVDSGRPALSASCRVSITVSDTN 721
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 126.331 bits (316), Expect = 1.552e-29 Identity = 144/598 (24.08%), Postives = 243/598 (40.64%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF---VSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPI-YFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFE--MKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI---------SLTKDIEAGKYDLFLQVTDNGNP 1937
D E VL + A D G + L + ++D+NDE P F Y E+ G ++ V A D + G+ G + Y + D + +D +G + K L ++++ L V+A D V + + D+N++ P YP+ YF I EN P V+ + D D G NG V+ Q+ +R ++N T R+ S+DRE+ + + D G +S I+ + V D + P F R +YS + EN +++ L+ N +L S + SF S+ S G I N +DRE+ YQ + ++ A+VSV+V D+N++ P + R S+E + E+ + + DKD G+N + Y E G + F I L V+ +D E + + D G + +++ V +LD NDN+P + S + + + G+ + V+A DAD+ S+ +TY + + +D TG I +L + A + + TD G P
Sbjct: 405 DREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNF--DPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSP-PLGSTAKVTVVVGDLNDNHPVF---------------YPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDA--------ARFQVNAVTGAVSTRV--SLDREERAV-YQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNANVTYLIVSGD-QRGSF---SIEWSGGRIFTANAIDREEQAFYQLRVVA-----NSGGVAGEASVSVLVHDVNNHAPVF-DRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVK--------YEIGEGNGGEK--FGIFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEV----GSLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRP 949 HSP 2 Score: 124.405 bits (311), Expect = 5.035e-29 Identity = 142/620 (22.90%), Postives = 272/620 (43.87%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT-----LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRI--RQSIDREKVSNPLNFSINCQDNGQP-LLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQD-----ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIF----DDKDIGENS--RISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS---ISIDPFTGEISLTKDIE----AGKYDLFLQVTDNGNPM---RNSSANLTIIIYQQN 1985
+ L+++A G + + + + D+N+ AP F +Y + ED V S V A D++SG G++ Y++ + + DG + ++ +++D+ T LTV A D+ T V + ++DVN+++P + S Y E V + D D G NG V + ++ F LDS + LR+ R+++ R+ + +FS+ D G+P L+ +QV V D N+ P F +S Y S+ E+ N + +L D D AL + N F +++ S+G+I + LDRE++ Y + + + + TV+V VLD NDN P++ + + + + S +G+L+ D+D G + R +I + T ++ +G+ + + + +D+E ++++ D G P + ++V++ D NDN P ++ +++ NI GT++ V A D D+ + L Y + + +IDP +GEI +I+ G +++ ++ TD P+ R++ N+T+++ +N
Sbjct: 727 YQLRVVANSGG---VAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGIFPDGQ---LYVR---YELDRETREEYSLTVSAMDTGVEPLSSSVT-VNVTVLDVNDNKPLFNSSS--------------YVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQV---NFELDS-----ETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDA--------STGQITLLGSLDREETASYTLVVSATDSG--TSPLAASCTVAVQVLDENDNPPRFTESL---LSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGS-----------VFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIME----NIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDEN 1286 HSP 3 Score: 106.301 bits (264), Expect = 1.892e-23 Identity = 115/500 (23.00%), Postives = 209/500 (41.80%), Query Frame = 3
Query: 261 CSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLA-----VGSVILKVHAIDRESGDFGKIIYKLIKNED--FSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQ---PLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQD---------ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFE--MKENNIPSYELGQLIFDDKDIGENS--RISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW 1691
+ +L + + D ND +P+F Y+ V ED A +VI V A D +SG FG++ Y L +ED ++ + +G + + +PL + + A + + + + ++D N++ P SV +D + E+ E+ P + I+ D DEG N +++ I + + R + + +L + +++DRE+ S N + D + L S + + + + D N+ FT +L+ ++ + + +D D AL+ + F L+++T GE+R+ LDRE Y ++ V++ + TS AT++V V D NDN P++ R +E + E+ P E+ +L D D G N R I+S T D L L V + +D E + ++ + D G P + S+ V + D ND P +
Sbjct: 1598 ATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRAR-ATDGGGLAATARLYVNVLDANDNAP--SVQNDSLAA------------EVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDP-------EGRFAVGNDG---QLSVARALDRERQSF-YNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVT---GEVRLVRELDREARQSYALTVLAVDKGR--PPLTSTATLAVTVGDANDNAPRFP-RREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTG-----------DFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAF 2054 HSP 4 Score: 100.908 bits (250), Expect = 9.343e-22 Identity = 109/430 (25.35%), Postives = 186/430 (43.26%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQP-QLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQT--TKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSN-PLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVI---DQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGEN 1445
D E IP + L ++A D G+P ++ LV+ + D+ND AP+F Y + E GS + V A+D +SG K+ Y ++ D + S+D ++G + +D+ + L + A D K +T + + ++DVN+ P + K +T + N P F V ++ D D G+NG V+ + +F LDS K+ +S+DRE++ PL + QD G P L ST + V V D N+ +F Y SI+EN+ + ++ D+ A + L + + F ++++T G + LDRE+ YQ + ++ + + S A V++ V D D P + SF + EN P +G + D+ N
Sbjct: 299 DRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDL--GWFSVDESTGLVTTDG---KVDREVASSVVLNISAQDQGAQ-PKTAYTSLTVTLLDVNDEPPLFT--QTKYVATAVENSLPGLF------------VVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDS--------LTGKVTTLKSLDREELEEYPL--VVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAG---DAARFQVNAVT---GAVSTRVSLDREERAVYQLQVTALDGG--HLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNAN 690 HSP 5 Score: 99.3673 bits (246), Expect = 2.298e-21 Identity = 123/597 (20.60%), Postives = 247/597 (41.37%), Query Frame = 3
Query: 249 QPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT--LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEV--SFINVV---DKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQ-DNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI-LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWI---YPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
+P + S ++ I + D+ND P F V+E+ G VI + A D + G + Y ++ + +FV +D SG + + L ++ + LTV A D + + + D N++ P S + Y ++ E+ + + + I V D D G G+V + ++ + + D L+ T L + + +DRE + + D G L +T L V+VLD N+ + + + E+ S+L + D D E + S+ F + + G++ + LDRE+ Y + V + A+ + +S VS+++ D+NDN P + S E++ + + D D G NS + + L T F ++ + +++ + +D E + + + D+G P + ++ V + D NDN P + Y +++ + GT++ R+ A D D ++ L Y++ + + +DP G +++ + ++ Y+L ++ D G P R+ +A++ + + N
Sbjct: 1493 RPPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSE--GAFV-VDAASGVLRASRRLDREERASYLLTVRASDGTHATDA----RLSVAVRDANDNSPRFSRHA--------------YSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSE---DSDWADGAFGLHPVTG--ALNVTRPLDRESRACYV-LRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGN----DGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYA-LATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAE-------DEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVN 2048 HSP 6 Score: 95.9005 bits (237), Expect = 3.418e-20 Identity = 135/600 (22.50%), Postives = 245/600 (40.83%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKL---------TLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSIL-SFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFT-SFATVSVV-VLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNC--------------KIDIHFHDEGFPKNHNKIS---IIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSI--SIDPFTG--EISLTKDIEAG 1895
D E ++ L + A D G L SS + + ++D+ND P F + +Y E+ VGS++ V A D ++G G + Y K + +F +D +G I + +FD + L + +V A D D V +F+ DVN++ P + +Y + E+ ++ + D DEG NG ++ I N + ++ +T Q L S+DRE+ ++ ++ D+G L ++ + V VLD+N+ P FT S S+ +E+ +L + D+D + +F ++ +S+G + + LD E Y+ ++ A+D + S AT+ VV V D NDN P ++ F NIP I +T T P ++G E + I+ ++D E C ++ + D+ P + + + + V + DENDN P ++ P++ + + + +G+ + ++A D D + + Y + +I +D TG E S D E+G
Sbjct: 821 DRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQ---VNF-ELDSETGRIASLR-VFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFA--------------KSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAI-------NEGNEGGKFTVDASTGQITL--LGSLDREETAS-YTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATF---AIDRSTGSVFLARRLDFETQRLYRLNV----SAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIP-------------------IGTRVITVTARDPDADVNG-ELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTA----ILVDGLRAAAGSVVGTLQASDPDEAENAAVRYAVTGGDAAILFRLDRRTGIIETSTELDRESG 1360 HSP 7 Score: 79.7221 bits (195), Expect = 2.793e-15 Identity = 149/619 (24.07%), Postives = 258/619 (41.68%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDIDK-LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNIS---VGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEG-KNGDVKCQIQTTKLLKNLFYLDS----RMRLNKNTYQYKLRIRQSIDREKVSNPL-NFSINCQDNGQPLLKS-TIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMES---FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNE-AQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL--KILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI--NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS-ISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E P + L + A D G P+ ++ + + D ND P F Y V ED VG+ + + + R G V D +G + ++PL F+ + TL++ A D T VI ++DVN++ P I + R+++ + E+ + + V D D NG++ I + F L + +R+ L++ +DRE++ P+ N +I DNG+P+ +S T L V V D N++ F S Y+ ++ E S + +D D+ LN+ +++ S S+ +S+G + +DRE + +I ++ AQ T +TS +V +LD+ND P + + EN++P + + D D+GEN + + + P E +F + L K+ +K S+D E + + + D G P + + V + D NDN P + YP V + I N GT +T V A D D ++ + Y+L A + ++ TG +S + E Y L + D G+ S A +TI +
Sbjct: 95 DREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAALRDL--LHRGRGPLA----------------VPFDPKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRAT-AVIQLLDVNDNDPAIRFVYLPPAARSAS------------VDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNE-RGHFVLHAPGVPGLRV--------LKVASQLDRERI--PMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADS------GLNAKLRYSIVSGNDLGWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSL---TVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYN------FDPDMPAQYRE-MFRLDSLTGKVTTLK-SLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVF-YP-----VQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITV 648 HSP 8 Score: 70.0922 bits (170), Expect = 2.227e-12 Identity = 46/174 (26.44%), Postives = 82/174 (47.13%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEI 707
D E + L ++A D G+P L S+ L + + D ND AP+F + Y + ED G+ +L++ A D + G G++ Y + + T +D GT+ + +PL D ++ L V A D ++ D V + + DVN+ P + + + G P+ L++
Sbjct: 1908 DREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGD--PTGDFRLDPVLGTLAVARPL-DRERTASYELAVRARDGG-GPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENTQGPPVLILQV 2077 HSP 9 Score: 57.7658 bits (138), Expect = 1.367e-8 Identity = 62/242 (25.62%), Postives = 97/242 (40.08%), Query Frame = 3
Query: 1308 VSVVVLDINDNVPQY--VGRMSFEMKENNIPSYELG-QLIFD---DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI-------LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTK--DIEAGK-YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
V VVV D+NDN P + G M KE+ +G Q++ D D+D+G N + Y + +SGNE+ + + L +D E + + + D G P+ + ++ + V + D NDN P + P+ +V S + L R R A + DP TG +S + D EA + Y L L+ D GNP + A I + N
Sbjct: 9 VRVVVGDVNDNAPSFPEPGVMEVAFKED----AAVGRQVLLDTAVDRDVGPN------GVNHHAY---KIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAALRDLLHRGRGPLA------------------VPFDPKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVN 219 HSP 10 Score: 52.7582 bits (125), Expect = 4.267e-7 Identity = 63/271 (23.25%), Postives = 117/271 (43.17%), Query Frame = 3
Query: 1212 NPLDREKSPRYQFSIFVVNEAQDNTKFTSFA--TVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPE----WIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSN-RLTYELKAKHDS---ISIDPFTGEISLTK-----DIEA-GKYDLFLQVTDNGNPM-RNSSANLTIII 1973
PLDRE +P Y ++ +A+D + V+V V D NDN P +FE P+Y + +D +G ++ L GP + + + ++ +Q +D+E + + D G P + + ++ +LD NDN+P ++ P++ V+ S GT V DADS ++N L+ + ++ + P + + K D E Y+L + +DNG P+ R+++A+L + +
Sbjct: 92 GPLDREANPSYALAV----QAEDGGSPRRYGRLQVNVTVQDANDNPP------AFEK-----PAYRAS--VAEDSPVGA----ALRDLLHRGRGPLA-------VPFDPKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDES---AAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYV 331
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004043.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004043.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 124.405 bits (311), Expect = 5.714e-29 Identity = 136/587 (23.17%), Postives = 240/587 (40.89%), Query Frame = 3
Query: 246 GQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK-DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI--NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
G+P+L + + + + D ND P+F A V ED +GS + V+A D ++G I Y+L + S++ ++G II L + L V A D +V+ + DVN+H P + LN + + + P V + D D G NGD++ + + F +D R + I + + + L ++ D G P + + V D E+P F S S E++ +I A +HL S N + ++ SGE+ + LD E YQ +V EA+D+ F+++ + V VLDINDN P++ + N P + L DKD G N ++ S + G +++ N E++ + ++D E + + ++ + D G P H + +++++ DENDN P + S +H+ + G + RV +DAD + +T+ L SI P TGEI++++ + + +P S ++TI++ N
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDADAGLNAIISYRLRGGD----GHFSVNPSTGQIITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTP------------RFLNAPYVAYAP--SSAPAGTAVFAVTARDADAGPNGDLRFSLSGSA--SAGFSVDPRRGV----------IHAARALQGPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGEFPR-FAPGPRSFSFREDQPPGTTITVVAARSSRRAGPVSYHLASGGNLG----DVFAVDPQSGEVSVHRALDHE----YQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVVLTAVDKDSGINGQVDYSIIDGNI-GNVFRVNPNS-----GEIRSV---STLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIFS-------AHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPSLPFSIHPSTGEITVSRRLNREDRSGYAVKVRASDPAWTVSTDVTIVVDDVN 533 HSP 2 Score: 80.1073 bits (196), Expect = 2.102e-15 Identity = 134/624 (21.47%), Postives = 264/624 (42.31%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFNE---FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSP----------RYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFD----DKDIGENSRISISSLTTTCYGPTEKLSGNED-LFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK--DIEAGK-YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D+E+ + L + A D G P + KL +D++DIND AP+F + + V E+ ++++ + A+D++SG G++ Y +I + + F ++ NSG I L ++ LTV+A D V+I + D N++ P TQ+ + + + E+ F V ++ +D DEG N + + LD + + + ++ + + ++RE S +++ + + ST + V V D N+ F ++ Y + E + ++++ + D D + + F + + NF + + SGEI PL R + P +Y F + ++ + +S ATV++ ++ N N P+++ R S + + G I D D D N +I+ S + GN F + L ++ S+ + + + D G P ++ + I+++ +EN P + +P L+ + +H +G+ L RV A D D+ + + Y + + S I +G++ L D E K Y+L + D G + + ++I + N
Sbjct: 295 DHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVV-LTAVDKDSGINGQVDYSII-DGNIGNVF-RVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCT-VKVLISVTDENDNSPRF---------TQIFSAH------VREDAAVGFPVLRVSTLDADEGPNAAITFSL-----------LDPSLPFSIHPSTGEITVSRRLNREDRS---GYAVKVRASDPAWTVSTDVTIV-VDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTENFR--------VGRDSGEIHSVRPL-RYRDPAGGGSGANLNKYSFVVTAMDRGR--PPLSSDATVTINIVVPNANAPRFLRERYSTPVA----ATVRAGTRILDMSAVDPDRDVNGQIAYSV-----------VGGNASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHP-PLELSLPENH---PAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVN 854 HSP 3 Score: 77.7962 bits (190), Expect = 1.050e-14 Identity = 116/519 (22.35%), Postives = 207/519 (39.88%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT--LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYL---DSRMR-LNKNTYQYKLRIRQSIDREK-VSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLS--------SLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVL-DINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGP-TEKLSGNE----DLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPE 1688
DYE + L + A D G + I + D+ND P A +Y V+ E+ G+ +L + A+D +S +Y L +D ++ +G + + L K T LTV A + + + V + I VN + P +R Y + E+ P V + D+D G +G V FY+ +SR + + N + ++ + +DRE+ S L + + +++ V + D N+ P +F+ + Y + E A + + + +S + SF + S+ +G I + +PLDRE P Y ++ V+ + T TV VV L D+NDN P ++ S ++ EN + L D D+ N GP T +L G++ F +S +L+ + +D E + + D G P + +++ +++LD+NDN E
Sbjct: 819 DYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSL---DDGEADLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPD-TFHYSTAQVHVQITGVNEYFPRFV----QRE----------YNFVVSESAPVGAPVGSVFATDRDAGIDGTV-------------FYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEA---------ASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGT---TVVVVALEDVNDNGP-FLLTSSAKVTENQPAGMTVLNLEAGDPDLPPNK------------GPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNPSE 1280 HSP 4 Score: 77.411 bits (189), Expect = 1.448e-14 Identity = 95/422 (22.51%), Postives = 169/422 (40.05%), Query Frame = 3
Query: 213 KFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-----------VSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK-DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIG 1439
K+ + A D G+P L S + I+I+ N AP+F+ + Y+ V + G+ IL + A+D + G+I Y ++ + S F S+ G++G+I ++TVEA D T +I + + N + P + +P L + EN+P ++ + D D G NG + I + D + + + + +D E N S+ D G + + V D N+ P + S+Y I EN ++L +D D+ S N + S ++ + F L Q +G + LD E Y+ ++ N +T S A V V + +N+ P++V R +F + E+ +G + D+D G
Sbjct: 616 KYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGG-NASRRFDVDAGGFLHLRASLAGDAGSI-----------FSVTVEARDRGRPPLSSRAT-AIISVTEENQYAPRFA--------------HPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASG---------DGSGLFDISRASGDVLLVGELDYE-TEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPS-NAVTMYSLDDGEADLF---VLNQKTGVLTTQGFLDYETKQTYELTVRAFNYP--DTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAG 994
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 124.405 bits (311), Expect = 5.725e-29 Identity = 136/587 (23.17%), Postives = 240/587 (40.89%), Query Frame = 3
Query: 246 GQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK-DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI--NIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
G+P+L + + + + D ND P+F A V ED +GS + V+A D ++G I Y+L + S++ ++G II L + L V A D +V+ + DVN+H P + LN + + + P V + D D G NGD++ + + F +D R + I + + + L ++ D G P + + V D E+P F S S E++ +I A +HL S N + ++ SGE+ + LD E YQ +V EA+D+ F+++ + V VLDINDN P++ + N P + L DKD G N ++ S + G +++ N E++ + ++D E + + ++ + D G P H + +++++ DENDN P + S +H+ + G + RV +DAD + +T+ L SI P TGEI++++ + + +P S ++TI++ N
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDADAGLNAIISYRLRGGD----GHFSVNPSTGQIITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTP------------RFLNAPYVAYAP--SSAPAGTAVFAVTARDADAGPNGDLRFSLSGSA--SAGFSVDPRRGV----------IHAARALQGPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGEFPR-FAPGPRSFSFREDQPPGTTITVVAARSSRRAGPVSYHLASGGNLG----DVFAVDPQSGEVSVHRALDHE----YQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVVLTAVDKDSGINGQVDYSIIDGNI-GNVFRVNPNS-----GEIRSV---STLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIFS-------AHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPSLPFSIHPSTGEITVSRRLNREDRSGYAVKVRASDPAWTVSTDVTIVVDDVN 533 HSP 2 Score: 80.1073 bits (196), Expect = 2.104e-15 Identity = 134/624 (21.47%), Postives = 264/624 (42.31%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFNE---FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSP----------RYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFD----DKDIGENSRISISSLTTTCYGPTEKLSGNED-LFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK--DIEAGK-YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D+E+ + L + A D G P + KL +D++DIND AP+F + + V E+ ++++ + A+D++SG G++ Y +I + + F ++ NSG I L ++ LTV+A D V+I + D N++ P TQ+ + + + E+ F V ++ +D DEG N + + LD + + + ++ + + ++RE S +++ + + ST + V V D N+ F ++ Y + E + ++++ + D D + + F + + NF + + SGEI PL R + P +Y F + ++ + +S ATV++ ++ N N P+++ R S + + G I D D D N +I+ S + GN F + L ++ S+ + + + D G P ++ + I+++ +EN P + +P L+ + +H +G+ L RV A D D+ + + Y + + S I +G++ L D E K Y+L + D G + + ++I + N
Sbjct: 295 DHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVV-LTAVDKDSGINGQVDYSII-DGNIGNVF-RVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCT-VKVLISVTDENDNSPRF---------TQIFSAH------VREDAAVGFPVLRVSTLDADEGPNAAITFSL-----------LDPSLPFSIHPSTGEITVSRRLNREDRS---GYAVKVRASDPAWTVSTDVTIV-VDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTENFR--------VGRDSGEIHSVRPL-RYRDPAGGGSGANLNKYSFVVTAMDRGR--PPLSSDATVTINIVVPNANAPRFLRERYSTPVA----ATVRAGTRILDMSAVDPDRDVNGQIAYSV-----------VGGNASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHP-PLELSLPENH---PAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVN 854 HSP 3 Score: 77.7962 bits (190), Expect = 1.051e-14 Identity = 116/519 (22.35%), Postives = 207/519 (39.88%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT--LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYL---DSRMR-LNKNTYQYKLRIRQSIDREK-VSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLS--------SLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVL-DINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGP-TEKLSGNE----DLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPE 1688
DYE + L + A D G + I + D+ND P A +Y V+ E+ G+ +L + A+D +S +Y L +D ++ +G + + L K T LTV A + + + V + I VN + P +R Y + E+ P V + D+D G +G V FY+ +SR + + N + ++ + +DRE+ S L + + +++ V + D N+ P +F+ + Y + E A + + + +S + SF + S+ +G I + +PLDRE P Y ++ V+ + T TV VV L D+NDN P ++ S ++ EN + L D D+ N GP T +L G++ F +S +L+ + +D E + + D G P + +++ +++LD+NDN E
Sbjct: 819 DYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSL---DDGEADLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPD-TFHYSTAQVHVQITGVNEYFPRFV----QRE----------YNFVVSESAPVGAPVGSVFATDRDAGIDGTV-------------FYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEA---------ASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGT---TVVVVALEDVNDNGP-FLLTSSAKVTENQPAGMTVLNLEAGDPDLPPNK------------GPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNPSE 1280 HSP 4 Score: 77.411 bits (189), Expect = 1.449e-14 Identity = 95/422 (22.51%), Postives = 169/422 (40.05%), Query Frame = 3
Query: 213 KFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSF-----------VSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK-DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIG 1439
K+ + A D G+P L S + I+I+ N AP+F+ + Y+ V + G+ IL + A+D + G+I Y ++ + S F S+ G++G+I ++TVEA D T +I + + N + P + +P L + EN+P ++ + D D G NG + I + D + + + + +D E N S+ D G + + V D N+ P + S+Y I EN ++L +D D+ S N + S ++ + F L Q +G + LD E Y+ ++ N +T S A V V + +N+ P++V R +F + E+ +G + D+D G
Sbjct: 616 KYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGG-NASRRFDVDAGGFLHLRASLAGDAGSI-----------FSVTVEARDRGRPPLSSRAT-AIISVTEENQYAPRFA--------------HPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASG---------DGSGLFDISRASGDVLLVGELDYE-TEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPS-NAVTMYSLDDGEADLF---VLNQKTGVLTTQGFLDYETKQTYELTVRAFNYP--DTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAG 994
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 165.236 bits (417), Expect = 2.052e-41 Identity = 163/618 (26.38%), Postives = 279/618 (45.15%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT-----LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNT--KFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNE-DLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW---IYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAK-HDSISIDPFTGEISLTK-DIE-AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
DYE ++ L + A D G P + ++ I I D+ND +P F NY+K + E +GS ++ V A D +SG G++ Y+LI + +F +ID NSG+I + L D+ T L VEA D + T V I + D+N++ P + G Y + E++ ++ + D D+ NGDV+ + D+ + NT + ++ +D EK + + ++ +D G P S +++V V D N+ P F +S Y+ ++ EN ++ D D+ +S++ N + F M+ F +GEI PLDRE Y +I A D + +F + TV++ + D NDN P + G F + E++ +GQL D+DIG N ++ + +SGN+ + F + IL V+ ++D E I + + + D G P+ SI V++LD NDN P + ++ + ++ +Q V+ D D S+ +T L + D+ +ID +S T D E Y L + D G+P ++++A + I I N
Sbjct: 437 DYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISG-NVKGAF-NIDANSGSIRVSSEL---DRETTPSYSLQVEARDGGSTSRSS-STRVTIALQDINDNSP-------------IFQGP--YVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALS-----------DNTDVFSINTSTGLITLKTQLDYEKKTQYM-VTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRF--------TGEITTRVPLDRETIASYSLTI----NADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYA-----------IISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQ-------VKVEDKDEGSNGAITLSLSGEGSDNFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVN 991 HSP 2 Score: 149.828 bits (377), Expect = 1.289e-36 Identity = 143/578 (24.74%), Postives = 264/578 (45.67%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQD--NTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEW---IYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSI--SIDPFTGEIS 1871
D E + + L A D G P + I+I+D+ND P F + YT V ED+A+G+ ++ V A D+++G+ + Y + ++D +G + + + L D ++ L L+V S D +H++I + D+N++ P S + Y + EN P +VS D+D NG + I +F +D + + I +S D E + + ++ +D G P+ T + + + D N++ +F+ SNYS I E+ ++++ D D+ L + N FN+++ +SG IR+ + LDRE +P Y + EA+D +T +S V++ + DINDN P + G F + E++ P +++GQ+ D D N + + LS N D+F I + ++ +K +DYE + + D G P + + V + D NDN P++ +Y ++ N+ +G + V A DADS ++ +++Y + + ++++ ++D FTGEI+
Sbjct: 230 DRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGN--TNHAFTLDAVTGVVTVSRSL-DFEQRSSYALGLSVTDRGSPPLT---DTSHLLINVNDINDNPPVFSPSA--------------YQSRVKENTPAGTQVS---ATDRDSSTNGALVFGIIKGN-DDGVFTIDGSTGI--------ISIAKSPDYENKTR-YDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDA--------NSGSIRVSSELDRETTPSYSLQV----EARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYA------------LSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGE-------NLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEIT 743 HSP 3 Score: 148.673 bits (374), Expect = 3.348e-36 Identity = 158/608 (25.99%), Postives = 272/608 (44.74%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQD--ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E + L++ A D G+P + + + I D+ND +P+F YT V E+ A GS IL+V A D ++G G++ Y +I + +F ID +G I + + D + L LT+ A DS W I V + N + + TS + G I V+ + D+DEG N V I + + F + N L +++ I+RE V +I D G P++ S L V V D N+ P +F +Y S+ EN + S+L+ A D D A + + + S N + + F ++S +SG I PLD E+ +Y + ++K+T+ V++ V+++ND P + + + ++EN+ S + ++ D+D S SL+ + G + D F I + I+ +D E + I + D G P N + + ILDENDN P++ S +++ N + ++ A DAD ++ R+TY L +++D+ I +G I+L + ++ YDL +Q D+G P + SS + + + N
Sbjct: 1162 DREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISG-NHGNAF-RIDSTTGRITVVG-VVDREALASYNLTISAKDSGVP----PWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSI-----------GSRVAVVTATDRDEGSNAQVFYSI--VRGDTSAFAI--------NAMNGVLTVKKEINRETVPT-YTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGN--DEKRFKINS---TSGVIMTTTPLDFEEKSQYGLEVTAT-----DSKYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRD-------SFGSLSYSIVG-----GKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILE----NSAPSSFSFKLAATDADEGTNARITYNL-SRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDIN 1713 HSP 4 Score: 133.65 bits (335), Expect = 1.270e-31 Identity = 152/613 (24.80%), Postives = 262/613 (42.74%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTR-SNYSLSIIENKDNFSILSFAVIDQD-----ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSG-NEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E P + LQ+ A D G SS ++ I + DIND +P F Y V E + G I +V A D + G + Y L N D SI+ ++G I LK L D +K T +TV A D S+ T V + + DVN++ P + +Y + EN V ++ D D G NG K+ ++ + M + + ++ R +DRE +++ + +IN D + + + + D+N+ FT S +++S ++ + D+D A+++ N N+F ++ SG + + + LDRE P Y + + T A++ V VLD+NDN P++ + S E++E+ + Q+ +DKD G N I++S LSG D F I + K +DYE ++ + D G P + + I++ NDN P ++ P+ + ++ IN T + ++ A D+D LT+++ + S ID +G IS+ K ++ Y L ++ T+ G+ + N TI + N
Sbjct: 542 DRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGP-YVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDV----FSINTSTGLITLKTQL-DYEKKTQYMVTVTAKDGGTP-SRSSLTVVKVMVDDVNDNPPQFA--------------KSLYTCTVGENLAAGVAVCYVTATDADSGANG---------KISYSILSGNENMAFAMDRFTGEITTRVPLDRETIAS-YSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISE-DSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLD--------PRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSIT--ASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLS------------LSGEGSDNFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAIN----THVVKLNATDSDGTP---LTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVN 1093 HSP 5 Score: 132.494 bits (332), Expect = 2.862e-31 Identity = 155/610 (25.41%), Postives = 272/610 (44.59%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK-DNFSILSFAVIDQDA---LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA-KHDSI-SIDPFTGEIS----LTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E + + L + A D G P S+ + I + D ND +P F + + + E +++GS + V A DR+ G ++ Y +++ + TS +I+ +G + +KK + + TLT+ A D D + + + DVN++ P + S Y + EN+ ++ V + D D G N ++ I + R N+ + +D E+ S + D+ + K+ + ++V ++ N+ FT+ NY+ S+ EN + S++ + D+D+ LS++ S+ F S+ Q SG I + LDRE Y + V + N ++ V++ +LD NDN P++ S + EN+ PS +L D D G N+RI T LS N+ + ++ + Q +D E + I D G P + I+I V ++D ND+ P I SSL V N T + R+ A DAD+ + LT+ L + +H S+ ++D TG+IS L ++ +A Y L + V D GNP +S A++ I + ++
Sbjct: 1267 DREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGD---TSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDK-ELTVVVNDVNDNPPVFNSQS--------------YIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSI---------ISGNDEKRFKINSTSGVIMTTTPLDFEEKSQ-YGLEVTATDS-KYTAKTNVTIRV--INLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKF--------SIDQRSGIISTADVLDRELVSLYAIQVRVTDAG--NPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARI------------TYNLSRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRP-LINSSSLRGSV---RENQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQA-VYTLRIGVADKGNPSLSSVADVIIDVIDED 1818 HSP 6 Score: 128.642 bits (322), Expect = 5.012e-30 Identity = 156/617 (25.28%), Postives = 268/617 (43.44%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKL--TLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP-----QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENS--RISISSLTTTCYGPTEKLSGN-EDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWI---YPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E + L + A + G I ++D+ND AP F +Y K + E+L +G + KV A DR+ G+ K+ Y+L + TS ++ +G + K+PL D+ +L V A D + S+ + + I D+N++ P S Y L + EN + + D D G NG V I + N F +DS ++ + +DRE +++ N +I+ +D+G P ST + + V D+N+ +F + S I E S + D+D S N S + +F ++++ +G + + ++RE P Y +I + + TS ++VVV D+NDN P Y+G ++EN+ S + + DD D+G N+ R SI +SGN E F I S ++ +D+E +++ D + K ++ + +++ ND P + Y +S+ N + T + +V A D DS S L+Y + DS SID +G IS ++ Y + ++VTD GNP ++ +TI I +N
Sbjct: 1058 DRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGD---TSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKP-SQSAVAAITLTINDLNDNSPQFSQSK--------------YTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGN-HGNAFRIDSTTG--------RITVVGVVDREALAS-YNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGS-NAQVFYSIVRGDTSAFAINAM---NGVLTVKKEINRETVPTYTLTIRASDRG--SPMMTSDKELTVVVNDVNDNPPVFNSQSYIG----SVRENSAQSTSVLTVAADDSDVGANAVLRYSI-------------ISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSKYTA---KTNVTIRVINLNDITPAFTQQNYTASV-------RENSPTSTSVVKVSASDRDSFGS--LSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDEN 1611 HSP 7 Score: 126.331 bits (316), Expect = 2.086e-29 Identity = 145/597 (24.29%), Postives = 264/597 (44.22%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNT--KFTSFATVSVVVLDINDNVPQYVG-RMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL-KILQVKQSMDYEFIHNCKIDIHFHDEGFP--KNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDI---EAGKYDLFLQVTDN 1928
DYE + L + A D G P ++ ++ I II++ND P FV+ + ED+A+ + ++K++A D D + + ++ E + S ID +SG I + K L TL V A ++ + + I ++DVN++ P + GS Y + EN P V+ + D+DEG+N V ++ K F ++ L + ++ +DRE ++ + + D+G+P + + + + D N+ F++S Y+L++ EN N S IL D DA ++++ N N F ++S ++G I + +DRE Y +I A+D+ + S A V++ V D NDN P + S+ + E + + D+D G N+++ S + G+ F I+ + +L VK+ ++ E + + I D G P + +++++VN D NDN P + S + +V N T + V A D+D ++ L Y + + +D I+ +G I T + E +Y L + TD+
Sbjct: 956 DYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDS---DGTPLTFDIV--EGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESV-YNNATIRVLDVNDNAPVFNPGS--------------YAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSK--FEVNPATGL--------VTTKRPLDREDQAS-YSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDS--------TTGRITVVGVVDREALASYNLTI----SAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYS-----------IVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVN--DVNDNPPVFNSQSYIGSV----RENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS 1492 HSP 8 Score: 108.997 bits (271), Expect = 5.244e-24 Identity = 146/580 (25.17%), Postives = 249/580 (42.93%), Query Frame = 3
Query: 279 VIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQD-----ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSF--ATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGN-EDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGK---YDLFLQVTDNGNPMRNSSANLTII 1970
+I + D+ND AP F Y V ED+AVGS++ ++ A+D + G ++ Y L+ + TS+ ++D S +I K FD + + + A D S+ V I I+DVN++RP S S Q Y + E+ + + DKD G N D++ T+ + F LD+ + + + +S+D E+ S+ ++ D G P L T L ++V D N+ P +F+ S Y + EN + +S D+D AL F N F ++ S+G I I D E RY ++ +A+D + A V++ + D+ND+ P + S ++ E+ + + + D D G R+ +SGN + F I + ++V +D E + + + D G + + + + D NDN P + P V +S + G ++ +V A DAD S+ + Y L D SI+ TG I+L ++ K Y + + D G P R+S LT++
Sbjct: 155 LITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGD---TSYFTVD--SQGVIRTKGAFDRETKASYQVALRAQDGGSP-SRSGQATVEIEILDVNDNRPVFS-------SAQ-------YTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSF-TSGNTNHAFTLDAVTGV--------VTVSRSLDFEQRSS-YALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQVS--ATDRDSSTNGALVFGIIKGNDDGVFTIDG--------STGIISIAKSPDYENKTRYDLTV----QARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEY-----------RLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPY----VFRVSE-SSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSS---LTVV 671 HSP 9 Score: 108.227 bits (269), Expect = 8.887e-24 Identity = 139/537 (25.88%), Postives = 240/537 (44.69%), Query Frame = 3
Query: 201 EFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK--DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKF--TSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI-LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDAD 1787
E +P + L + A D G P + S ++L + + D+ND P F +++Y V+E+ A + +L V A D + G + Y +I D I+ SG I+ PL + + L V A DS ++ +K T+V I +I++N+ P + + Y + EN+P + V ++ D+D G + I K + F +D R + + +DRE VS + D G P L + + + +LD+N+ F S+YS SI+EN +FS A D D + N S N ++F + + SSG I + PLDRE Y +I +A+D+ S T+ V V+DIND+ P + ++EN + +++ D D G N+ ++ S L+ ++ +F + + K +D E + I D+G P + +I++++DE+DN P + P+ + V IS ++ G + +V A D D
Sbjct: 1373 ETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGND--EKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS-KYTAK---TNVTIRVINLNDITPAFTQQN--------------YTASVRENSPTSTSVVKVSASDRD--SFGSLSYSIVGGKD-SDKFSIDQRSGI--------ISTADVLDRELVS-LYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFS-FKLAATDADEGTNARITYNLSRN---DAFMIGA---SSGVITLAQPLDRENKSTYDLAI----QARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLSNE----------HKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRF-QPTEYN--VTISE-SLPRGASIVQVTARDID 1852 HSP 10 Score: 97.8265 bits (242), Expect = 1.254e-20 Identity = 131/574 (22.82%), Postives = 244/574 (42.51%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHV----VIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNED-LFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDIE 1889
D E ++ L ++A D +VID+ D ND AP+F +Y ++E+ V + V A DR+SG I Y L E+ F+ ++ +G I PL K + T+ S FD H +I + DVN++ P ++ +Y ++E+ V + VD D G N + + + + F +DS Q +R + + DRE ++ ++ QD G P +++++LD N+ +F+ + Y+ S+ E+ ++++ D+D + + + ++ +F L ++T G + + LD E+ Y + V + + T + + + V DINDN P + + N P+ Q+ D+D N + +G + GN+D +F I I+ + +S DYE + + D G P ++ + + I D ND+ P + PS+ + S + G+ + V A D DS RL Y L + + + +ID +G I ++ +++
Sbjct: 29 DRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAI-VTATDRDSGTNAAITYSLFSGEN---KFM-MNSKTGEIRTVTPLDHETKDSYTMRI-------SAFDGKHTTFVPLITVDDVNDNAPFFALS--------------VYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGD--TSYFTVDS---------QGVIRTKGAFDRETKAS-YQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVT---GVVTVSRSLDFEQRSSYALGLSVTDRG--SPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT--QVSATDRDSSTNGAL--------VFG---IIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVF-SPSNYSKQIPESTV---IGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELD 542 HSP 11 Score: 88.5817 bits (218), Expect = 9.918e-18 Identity = 83/293 (28.33%), Postives = 138/293 (47.10%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT--LTVEAHDSAEHNSKFDWTHVVI--FIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN 1061
D E + + +Q+ D G P L + + I I+D ND +PKF + +Y+ + E+ A S K+ A D + G +I Y L +N+ F I +SG I L +PL +K T L ++A D H + + + I +ID+N+HRP I+ S L G + EN P+ V I D D G N ++ + + + K++F LD NT + + +DRE+ + I D G P L S + +DV+D+++ F + Y+++I E+
Sbjct: 1576 DRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSRNDAF-----MIGASSGVITLAQPLDRENKSTYDLAIQARD---HGTPPQASSITIRVTVIDINDHRPLINSSS--------LRG------SVRENQPKETHVMRILASDADTGLNAELTFSLLSNE-HKSVFTLD-------NTTG-DISTKVPLDREQQA-VYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYNVTISES 1836
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 164.851 bits (416), Expect = 3.544e-41 Identity = 160/607 (26.36%), Postives = 281/607 (46.29%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FD-IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVS----FINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN-KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHD---SISIDPFTGEISLTKDIEA---GKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E +P + LQ+ A D G P ++ + I ++D+ND P+F K Y+ ++ED+ V ++ V A D + G G++ ++++ D + F SI+ +G + +K+ L ++ I L V A D + ++ T V I +IDVN++ P V S +T PEN+ V + DKD G NG++ T ++N D +N+NT + I++ +DREKV F I +D G P + T + + +LD N+ P F++ Y SI EN + S+L ID D+ N + S++ + F ++ G I + L+ Y FS+ + + +S A V V V D N + P++ R S E+KE+ + ++ D+D G N++IS S T ++ +G +++ S+D E + + ++ D G P+ K + ++I D NDN+P ++ PS V +I+ G ++ V A DAD + ++ Y + D + +ID G I K ++ +Y+L + TD G P +S + +I+
Sbjct: 193 DREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMN--FFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQP-FLYNQTTVDIALIDVNDNAPQF-VSSHFQTMI-----------------PENYAVGQEFYRVQAYDKDHGTNGEI-----TFSFMQN----DLPFSINENTG--GISIKEELDREKVPK-FTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRINP----QGLITLSCTLNYNTKHVYVFSV-----SASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTG-----------VIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVRE----DIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVIL 742 HSP 2 Score: 144.821 bits (364), Expect = 5.407e-35 Identity = 168/642 (26.17%), Postives = 282/642 (43.93%), Query Frame = 3
Query: 75 DSAQNGVYHYLLECSQK-SHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKL---TLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN----KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCY----GPTEKL------SGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLF---LQVTDNGNP 1937
DS NG+ Y + SQ YF + + + LD EF+ + ++ A D G+P L L I+++D+ND P F Y + ED ++G +L V A D +SG G++ Y I N D S SI SG + + K L D +K+ TL V+A D T V I ++DVN+ P S +Y I E+ P N V+ + D D+G NG+V +I + + N F ++ R+N ++R++Q +D E + N + QD GQP L + + + ++D N+ F S++ I EN ++ + + ++ D+D + E + M++ S+ +++G I I LDREK P++ F I ++ + T A +++ +LDINDN P+ F +E + I ENSR S L GPT + SG++ F I+ ++ + +++Y H + D + + VN+ D N + PE+ S V + + GT + V A D D+ S+ +++Y + S+D TG I ++ K D + + TD+G P
Sbjct: 48 DSGSNGMIRYSMSPSQNLMSATYF--SIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKY-CILNSDGDNSAFSIGEVSGAVTVMKKL-DREKVPTYTLQVQAQDQGNPPRSATVT-VKITLLDVNDCTPQFS--------------KKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDM-NFFSIN---RING-----EVRVKQKLDYEMI-GVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAY---DKDHGTNGEITFSF-----MQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGT--AQITITLLDINDNPPK------FSQEEYH-------------TSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDGML---SSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASL----GTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIP 624 HSP 3 Score: 123.635 bits (309), Expect = 1.894e-28 Identity = 135/508 (26.57%), Postives = 224/508 (44.09%), Query Frame = 3
Query: 312 PKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDF-STSFVSIDGNSGTIILKKPLFD--IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFD----DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSN 1802
P+F V ED VG+V+ V A D +SG G I Y + +++ S ++ SID +G I K+ L +D+ V+A D E + + + + I ++DVN++ P IY +I E+ V + D D G NG+VK I + + F + + + + +DREKV + QD G P +T+ +++ +LD N+ F++ YS +I E+ N + + D D S E F + S N+ N S+ + +GE+R+ LD E F++ V + + + TV + ++D+NDN PQ+V M N Y +GQ + DKD G N I+ S + N+ F I+E + +K+ +D E + I D+G P I + +LD NDN P++ S + +I+ N + GT + +V+AID DS +N
Sbjct: 18 PQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLE-GYMDLTINVLDVNDNGPIFERN--------------IYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGE--------VSGAVTVMKKLDREKVPT-YTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMN-----FFSINRINGEVRVKQKLDYEMIG--VFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPEN---YAVGQEFYRVQAYDKDHGTNGEITFSFMQ------------NDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKF---SQEEYHTSIAE-NSRWGTSVLQVKAIDPDSGPTN 475 HSP 4 Score: 76.6406 bits (187), Expect = 4.822e-14 Identity = 94/406 (23.15%), Postives = 173/406 (42.61%), Query Frame = 3
Query: 258 LCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTI----ILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQD-----ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVG-RMSFEMKENNIPSYELGQLIFDDKDIGE 1442
L S+ + +++ D N AP+F ++Y+ V+ED ++G+ +L V A DR++G KI Y + F S+D +G I L + D + +T H + +K + V I I DVN++ P P Y ++ E+ V ++ D D GKN + + + F +DS Q +R + +DRE + ++ D G P ++++ ++V + D + P LF + Y +++ E+ S +++ QD + ++ NS F+ + ++G I+ LD E Y+ ++ A + FT TV V + DINDN P M+ ++E +P ++ D D+ +
Sbjct: 523 LSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI---ATLVPEF-SVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAK---SFVYIHIADVNDNDPVFL--------------KPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDST--------QGIIRTLKPLDRETIPE-YELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFD--------INPNTGAIQTLMKLDYETQSEYRLTV----RATLSPFFTE-TTVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPDVSD 885 HSP 5 Score: 62.7734 bits (151), Expect = 8.092e-10 Identity = 63/243 (25.93%), Postives = 103/243 (42.39%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI------QTTKLLKNLFYLDSRMRLNKNTY-QYKLRIRQSI 896
D E + + ++ A D G PQL + + I I D+ND P F+ +Y V+ED+ G +++V A D + G +IIY N D +F +ID G I KPL I + LTV A D + V + + DV + P L P+Y + + E+ P V + +D + I Q + N + + M+L+ T +Y+L +R ++
Sbjct: 605 DREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTF-TIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQAS-VKVKVILEDVKDSPP--------------LFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRATL 831
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO33359 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSF2]) HSP 1 Score: 137.117 bits (344), Expect = 4.537e-33 Identity = 166/659 (25.19%), Postives = 290/659 (44.01%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSS--QKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKP----------------------LFDIDKLTLTVEAHDSAEHNSKF--DWTHVVI--------FIIDVNNHRPNISVGS-------DKRTSTQLL---------------NGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLS---SLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE--LKILQVKQSMDYEFIHNCKIDIHFHDEGFPK-NHNKISII-VNILDENDNEP---EWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYE-LKAKHDS-ISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSS 1952
D+E ++ L + D G P L S +VI ++D ND P+F K YT V E+ VG+V+L+V A D++SG + Y I + + +FV I +SG I L KP L I ++ + V EH +F ++ + I I+ V ++SVG+ D +S L Y E++EN +V + D+DEG NG V I T+ +K +F +S + + + +DRE V N + QD G P ++ ++V+VLD N+ P +FT Y+L + E IL + D+D + +N+ + ++ +S S+ ++G+I I +D E+ Y F +F + + + T ++V + ++D+NDN P ++ R ++ EN + Q+ D D N ++ S L GN D ++ + ++ +S+DYE + + I D G P N ++ ++ V++++ NDN P + +Y +S+D + H+ + RV A D DS + ++ + L+ D +D TG ++ K + + +Y L +Q TD G+P NSS
Sbjct: 173 DFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGTVVLRVTAHDKDSGPNAMLKYS-IHSGNTDDAFVII-ADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLVNQTGDITLARELDYETRRRYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSS-VKGVFTTNSTTGV--------VSLTAELDRESVYQ-YNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDD---KDEGVNAEIRYFLKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGE--ARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFS-----------ILGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHV-------ILRVTASDLDSSLNGKVLFSILEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSS 796 HSP 2 Score: 110.923 bits (276), Expect = 8.237e-25 Identity = 163/669 (24.36%), Postives = 280/669 (41.85%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKL---TLTVEAHDSAEHN-SKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYL-DSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKST--IILQVDVLDQNEYPALFTRSNYSLSIIEN-------------KDNFSILS-FAVIDQDALSFNEFHLNSSNNFNM--------------ESF-HLSSLTQ----------------------------------SSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVG-RMSFEMKENNIPSYELGQLIF-------DDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH--DSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSS 1952
DYE + + A D G P + + + I D ND P F Y V E+ +G+++ +V A+D++S +IY I+N + + SF +ID ++G I+ +K FD +K LT+ D+ S ++ +VVI ++D N++ P + KR Y ++EN V + DKD G N +K I + + DS + + + +D+E + N + D G P L+S +++ V V NE+ F Y+ SI EN +D+ S+ + F + +DA S F +N + + + E + +++S TQ ++G + + LDRE YQ+++ VV + + T+ A V V VLD NDN P + + ++ E + +G I DDKD G N+ I ++K S N+ I+ +KQ++DYE + ++ D G + S+ + I+D NDN P ++ +V N+ GT +T+V A D DS + ++ + + + ID TG ++ K + + +Y L +Q TD G+P NSS
Sbjct: 68 DYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYS-IQNGNNNGSF-TIDNSTGEIMTRKE-FDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEF---AQKR-----------YTATVYENFTVGTVVLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVIIADSG----------DISLDKPLDKETIEN-YTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLVNQTGDITLARELDYETRRRYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVFTTNSTTGVVSLTAELDRESV--YQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSE----ATSIGTRILRVSANDRDDKDEGVNAEIRYFLKDAIV---SKKFSINDTTGQIT------IKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVE----NVAIGTPVTQVTASDLDSSLNGKVLFSILGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSS 689 HSP 3 Score: 88.5817 bits (218), Expect = 6.513e-18 Identity = 97/400 (24.25%), Postives = 178/400 (44.50%), Query Frame = 3
Query: 720 PENFEV--SFINVV--DKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNED--LFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNIS-HINIQSGTKLTRVRAIDADSVSSNRLTYELK-AKHDSISIDPFTGEISLTKDIE 1889
PE+F V + + V+ D+D N V I + + F +D+ + +++ ++ ++ +FS+ +D G P+ + + V + D N+ +F Y + EN +I++ +D+D+ S + + N N SF ++ S+GEI D EK+ RY +I V + +FA V ++V+D NDN P++ R + + EN + ++ DKD G N+ + S SGN D I++ + + + +D E I N + + D G P + ++VN++ NE P L+ N S N+ GT + RVRA++ D R Y +K A + + TG+I+L ++++
Sbjct: 13 PEDFTVGGTLLTVLARDQDAALNARVTYSIVSFSTESDYFVIDNITGVVRSSKEFDYETQRM---------YSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQNGNNNGSF---TIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGTVVLRVTAHDKDSGPNAMLKYS-----------IHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHA---PRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLVNQTGDITLARELD 386 HSP 4 Score: 80.8777 bits (198), Expect = 1.662e-15 Identity = 112/437 (25.63%), Postives = 188/437 (43.02%), Query Frame = 3
Query: 75 DSAQNG-VYHYLLECSQKSHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFG--KIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVV-IFIIDVNNHRPNISVGSDKRTSTQLLNGYPI-YFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKST--IILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP 1346
D NG V++Y++ S K + + + L LD E + ++ + ++A D G P +S + ++++D ND P F YT + E ++G+ IL+V A DR+ D G I +K+ S F SI+ +G I +K+ + ++ + + E S ++ + V I IIDVN++RP P Y++++ EN V+ + D D NG V I L N D + +++NT + +S+D E V+ I D G P L S+ +L V V++ N+ +F++ YS SI EN IL D D+ + F+ NS F ++ Q++G + LD E Y I + + + V V++INDN P
Sbjct: 416 DEGINGQVFYYIVTSSVKG-----VFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKF-SINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYF---------------LPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFSI----LGGN---SDGKFVIDQNT--GVVTTNKSLDYEDVTE-YTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFSILEGNSDGKFVVD--------QNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSP 813
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO41767 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3G3]) HSP 1 Score: 131.339 bits (329), Expect = 7.482e-31 Identity = 169/604 (27.98%), Postives = 278/604 (46.03%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL---FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIF--ENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRM-RLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEY---PALFTRSNYSLSIIENKDNFSILSFAVI------DQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLI--FDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE--LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAK--HDSISIDPFTGEISLTKDIEA--GKYDLFLQVTDNGNP 1937
D+E + L + A D L ++ ++I+I+D+NDEAP F Y V+ E+L GS +++V A D +SG G ++ I + +FV ID SG I +PL F + LTV A D D T V I D N+++P +K+ Y + +F + ++F + + D+D G N D++ I T N F +DSR + N +D E + +I +DNG P L ++ + +DV+ N+ +F YS I E+K I SF +I D D +++N N N F ++ + G I + + LDRE+ Y + EA D T+ V++ +LD+NDN PQ R E + + + ++G L+ D D G N + C T K + LF I +IL VK +DYE + + I D G PK S++V++ D ND++PE++ P ++ V++S ++GT + RV A D D ++++L Y + + + S+S+D +G + + + +Y L +Q TD G P
Sbjct: 1063 DHEVADHYWLTVQAKDGESYPLYTNIPVLINIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSG--GSLLRYTITKGNEQNNFV-IDPQSGLITTLRPLDREFK-SEYKLTVSASDGGTPPVSTDVTFTV-KITDENDNQPEFK---EKQ-----------YVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYSI-TKGNRDNKFIIDSRSGEIFTNV--------SLVDGES----YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKNAPVFWNKQYSADIQEDK---RINSFVLIIGAEDPDFDQITYNIASGNHGNKFTIDRY--------GGFITVAHSLDREEKSFYSLRV----EATDGYN-TASVPVTINILDVNDNSPQPARR---EYRAHVAENSDVGTLVTTVKDPDAGVNGEVEY------CIVQTAKAE-SASLFKIESHSGRILTVK-PLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSP-LFESEVDVS---AKAGTAILRVIATDKDDGTNSKLKYSIVSGNTNKSLSVDQNSGVVKVAGRLSTLVHQYALKVQSTDGGEP 1603 HSP 2 Score: 122.865 bits (307), Expect = 3.186e-28 Identity = 153/613 (24.96%), Postives = 267/613 (43.56%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYF-LEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLL---KSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSS--NNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVV--VLDINDNVPQYVGRMSFEMKENNIPS-YELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI--SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL-KAKHDS-ISIDPFTGEISLTKDIEAGK-YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E I + L + A D G+ + + L + I D+ND +P F Y + E++ VG + VHA D++ G G I Y+++ DF F ++ SG + + L + + + ++A DS+ N K THV++ ++D+N++ P + P F + + E+ N V+ I+ D D G G+++ + +S + N ++ +R+RQ +D E+ S N ++ D G P L ++ +DV + + P SI EN S + VI A + ++L + + ++ F + T G IR LD E + Y ++ +A+D + + + V+ ++D+ND P + + + N+PS + Q+ D D G S+ T T GNE ++ + ++ + +D EF K+ + D G P ++ V I DENDN+PE+ + V + G L +V A D D S+ L Y + K D+ ID +GEI + G+ YDL + DNG P ++S N+ I + Q N
Sbjct: 750 DRETISSYTLNISAVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYEVTLPENITVGQTVTHVHASDKDQGTNGFITYQIVN--DFGGKF-RVNRISGVVSVGDYLDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLLDINDNSPIVK---------------PKKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEFSLP-----------ESTRKFNIDSKSGVIRLRQRLDFEQKST-YNLTVRVTDKGSPALFTDVEVVVNVLDVNENSLAPVFSGGRILETSINEN----SPVGTVVISPKATDQDSWYLKYAIIDGTGVDKFIIDPDT---GAIRTAGELDHEVADHYWLTV----QAKDGESYPLYTNIPVLINIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSGG----SLLRYTIT--------KGNEQNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGGTPPVSTDVTFTVKITDENDNQPEFKEKQYVVGVFARQATSKSFG--LYQVVATDEDIGSNADLRYSITKGNRDNKFIIDSRSGEIFTNVSLVDGESYDLTIVAEDNGLPKLSTSTNVLIDVIQGN 1307 HSP 3 Score: 118.627 bits (296), Expect = 6.630e-27 Identity = 142/610 (23.28%), Postives = 263/610 (43.11%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKF-DWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK--DIEAGK-YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
DYE ++V+ ++ ++ + +V+ ++DIND PKFV+ Y + E++ +GS +L+V A D +SG G + Y L+ + ID ++G I + L + + + + ++ T V ++DVN+ P S + + E+ V+ I D+D T+L + D + R + + S+DRE V + + +I+ D L S +++D+ D N+ P + T+S Y I EN ++L+ D D L+++ F ++ +++L + LDRE P Y F + A D ++ +S+ + D+NDN P + F + P + L Q+ DD D+G N +++ SL T G +G I+ +++ ++ E N +++ D G P + ++ + +L+ ND PE+ + NV + I G ++ RVRA+ +S S++ +TY + DS SID G I + + D E K Y L ++ +D G P+ S++ + I + N
Sbjct: 2716 DYEIRNRYVM-IVEANVSAINQIARTVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKDKLVKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDTPPKFSQSE--------------FMASVKEDALIGQSVTTITATDED-----------LNTELYYFILSGDPQARFGIERKTGVIFVHGSLDRESVGS-YDLNISASDG---LFTSFAQMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAELTYSVFGQGFGTFAVDKNGKMTNLVE----------LDRETRPFYNFMV----SAADIGGQACYSNISIHLDDVNDNRPLFSQSSYFTAVYEDAPLKKVLLQVKADDADVGVNRKLTY-SLVTDAGGTFTIETGT---------GIISLEKPLNRELKENYTLNVEVMDGGTPPLSSIATVQIKVLNINDVPPEFSHSIYHGNVSEDAPI----GNEVVRVRAVSRES-SNDVITYAILRGADSGLFSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSYVRISVTDSN 3266 HSP 4 Score: 104.76 bits (260), Expect = 1.171e-22 Identity = 147/593 (24.79%), Postives = 255/593 (43.00%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFD--IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKN----LFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENK--DNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFA--TVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE----LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL-KAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTD 1925
D E P + + A DIG Q C S + I + D+ND P F +Y V ED + V+L+V A D + G K+ Y L+ D +F +I+ +G I L+KPL + TL VE D T V I ++++N+ P S + IY + E+ P EV + V ++ + + T +L+ LF +D + + + + +D E + ++ D G P+L+ST +++ V D N+ F+ YS + EN F + FA D+D+ + + + + + + F + + +G I++ +DRE+ Y+ + AQD A V + V D+NDN P++ ++ + E+++P+ + L D+D N +L +SG+ F + KI V S D ++ ++ + D G P ++SI V I E+ P ++P L VN+ N+ G + RV+A D D + L Y L ++ S+ + G + +I G Y+L + VTD
Sbjct: 3025 DRETRPFYNFMVSAADIGG-QACYSN-ISIHLDDVNDNRPLFSQSSYFTAVYEDAPLKKVLLQVKADDADVGVNRKLTYSLVT--DAGGTF-TIETGTGIISLEKPLNRELKENYTLNVEVMDGGTPPLSSIAT-VQIKVLNINDVPPEFS--------------HSIYHGNVSEDAPIGNEVVRVRAVSRESSND------VITYAILRGADSGLFSIDRK--------NGTIHVNRKLDYE-TTKLYTLTVEASDAGPPVLRSTSYVRISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVFAT-DRDSGTNAQIKYSIAEGNDAKKFK---IVEETGVIKVSGDIDREEVASYRLKV----RAQDQGLPPQVADTVVDIEVTDVNDNSPEFSSTNLTTVLSESSLPNAAVIHLRPHDRDALGNGAPYQFTL----------ISGDASRFKLHSNGLITKIGDVSHS-DGQY----RLRVLVADNGHPPQSTEVSITVKIA-ESKTHPPNVHP--LTVYVNLYGSNLNGGV-IGRVKATDKD---GDLLHYSLVSSEQSSLLMISDEGTVRARANISPGTYNLNVSVTD 3552 HSP 5 Score: 103.219 bits (256), Expect = 3.053e-22 Identity = 140/596 (23.49%), Postives = 257/596 (43.12%), Query Frame = 3
Query: 201 EFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKL-TLTVEAHDSAEHNSKFDWTHVVIFIID---VNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDV-KCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRI--SISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDY-----EFIHNCKIDIHFHDEGFP-KNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDAD-SVSSNRLTYE--LKAKHDSISIDPFTGEISLTKDIEA--GKYDLFLQVTDN 1928
E + + L ++ D + K+ I + D ND P F+ K Y K + ED+ + + I ++ A+D + G G I Y ++ +TSF +I+ SG + + + L + ++ LTV A D A SK + I++ VN P SV TQL N + + ++DKD+G NGD+ + +I + LD + + Y +++ + +DRE N ++ D G P+ + +L+V+VLD+N+ F +S Y ++ E + +L D+DA S + + F ++S T G+I LD E R+ ++ ++ ++ S V V +LD ND+ P++ ++ E+ P + + +D D G N ++ S+++L + E +G I++ ++D EFI+ + + D G P + + + + + + NDN P + N+ + N G +T V AID D S L Y+ + S+DP TGE+ + + ++ L ++ TD
Sbjct: 66 ESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYYSF---KEKTTSF-AINPISGVVSVAQKLSNSARIHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSV------KTQLQN---------VSEGTSGIVYATLGIIDKDKGSNGDIDRVEITSGN-------LDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGKFEINSKT---GQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLRPVPF-EIEPDTG-----------IIRTTTNLDRDTGLPEFIN---LQVRASDFGTPLRRETETLVKMRVKEMNDNAP--VLKQFKCNI--LVDRNAPVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGELRTARSLRGLQREFTLIIKATDG 613 HSP 6 Score: 101.679 bits (252), Expect = 1.009e-21 Identity = 136/612 (22.22%), Postives = 248/612 (40.52%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIIL----KKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNN------FNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFW--ISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPF--TGEISLTKDIEA--GKYDLFLQVTDNGNPMRNSSANLTIIIYQ 1979
D E + + L + A D S ++ IDI D ND P Y + ++E+ +GS +L V A D + G ++ Y + + F T V +G ++ +P ++ V A D ++++ I + DVN++RP S S YF ++E+ P + + D D G N + L D+ T + + + ++RE N ++ D G P L S +Q+ VL+ N+ P F+ S Y ++ E+ A I + + SSN+ L S+ + +G I + LD E + Y ++ + + TS+ +SV D NDN P++ R S ++ EN+ + Q+ D+D G N++I S GN+ + + E +++V +D E + + ++ + D+G P + + + D NDN PE+ S N+ + + + +R D D++ N Y+ S G I+ D+ G+Y L + V DNG+P +++ ++T+ I +
Sbjct: 2925 DRESVGSYDLNISASD---GLFTSFAQMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAELTYSVF-GQGFGTFAVDKNGKMTNLVELDRETRPFYN-----FMVSAADIGGQAC---YSNISIHLDDVNDNRPLFSQSS--------------YFTAVYEDAPLKKVLLQVKADDADVGVN----------RKLTYSLVTDAGGTFTIETGTGIISLEKPLNRELKEN-YTLNVEVMDGGTPPLSSIATVQIKVLNINDVPPEFSHSIYHGNVSED---------APIGNEVVRVRAVSRESSNDVITYAILRGADSGLFSIDRKNGTIHVNRKLDYETTKLYTLTVEASDAGPPVLRSTSYVRISVT--DSNDNGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSIA-----------EGNDAKKFKIVEETGVIKVSGDIDREEVASYRLKVRAQDQGLPPQVADTVVDIEVTDVNDNSPEF----SSTNLTTVLSESSLPNAAVIHLRPHDRDALG-NGAPYQFTLISGDASRFKLHSNGLITKIGDVSHSDGQYRLRVLVADNGHPPQSTEVSITVKIAE 3472 HSP 7 Score: 94.3597 bits (233), Expect = 1.817e-19 Identity = 149/599 (24.87%), Postives = 262/599 (43.74%), Query Frame = 3
Query: 222 LQLIACDIGQPQLCSSQKLVIDIIDINDE---APKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK--LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVK-CQIQTTKL-LKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSI-IENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINI----QSGTKLTRVRAIDADSVSSNRLTYEL--KAKHDSISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANLTI 1967
L ++A D G P+L +S ++ID+I N AP F K Y+ +QED + S +L + A E DF +I Y I + + F +ID G I + L +K +L VEA D S V I I+DVN++ P + +R Y + EN+ V+ V D D G NG+V+ C +QT K +LF ++S + ++ + +D E + + +I D G P ++ + V V D N++ F + + + K +IL D+D + ++ + + +S S+ Q+SG +++ R + +Q+++ V + + V V V I N + + EN+ P + ++++ G I + C+ D + ++ K+S D E + +CK++I + H+ +IV I D+NDN+P + + +V S G++L V A D D +S ++LTYE+ + D SI P TG I+ K ++ +Y ++VTD+GNP ++ A++ I
Sbjct: 1281 LTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKNAPVFWNKQYSADIQEDKRINSFVLIIGA---EDPDFDQITYN-IASGNHGNKF-TIDRYGGFITVAHSLDREEKSFYSLRVEATDGYNTAS----VPVTINILDVNDNSPQPA----RRE----------YRAHVAENSDVGTLVT--TVKDPDAGVNGEVEYCIVQTAKAESASLFKIES--------HSGRILTVKPLDYETMQEHV-LTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVSAKAGTAILRVIATDKDDGTNSKLKYSIVSGNTNKSL---SVDQNSGVVKVAG---RLSTLVHQYALKVQSTDGGEPPLKTQVDVKVKVRGIVKNFAFEKPKYEVSLPENSPPDQAIATVVYN----GILPVYEIVPGRSPCW---------RDFTVQRQSGVIISKKSFDAEEVTHCKLEIRANSTD--GQHSSTLVIVTIQDKNDNQPIFEHARITGHVTEGSPQGTAVLDHKGSQLVAV-ATDQD-ISGDKLTYEIVETSARDVFSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKI 1822 HSP 8 Score: 94.3597 bits (233), Expect = 1.977e-19 Identity = 140/616 (22.73%), Postives = 257/616 (41.72%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNP-LNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNF---NMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNED----LFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAK----HDSISIDPFTGEISLTKDIEAGK---YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
DYE + ++A D G+P L ++ + ++D ND AP+F Y + + G + ++ A D + GD K+ Y + + ID SG I L + + I + L VE DS ++ + V + I D N+H P S +Y + EN PE V+ ++ D D G + I + ++ F +D+ + L R DRE S ++ I D G +++V ++D+N+ +F NY +I + +L + D DA S N++ + ++ + ++ ++G I++ RE + ++ FV+ + N S A+V + VL+ + + + G+ +++ + E+GQ++ G N + + Y + GN D F + ++V +DYE I N + I + + ++V +LD ND P+++ L ++ NI G+K+ RV A D DS S+ +TY L +K + ID TG I+ ++ K ++ ++ TDNG S + I+ N
Sbjct: 2301 DYESRVVHEMIIVAADEGKPSLTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSITGGQ--GRQHFQIDSQSGVITLSR-VVGIKQGKVYGLDVEVSDSVHVST----SKVRVIIGDTNDHSPIFS--------------EDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRK-FRIDADSGM--------LYSRLMFDRENSSQAIMSVPIRATDGGGRF--GFCVVEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASS------NAALTYVIVGHQTPPVFTINAATGVIQV----SREPEVK-SYNFFVLVKDGGNPLLRSIASVKITVLERDARILHF-GKSKYDVTVGE--NAEMGQIV-----TGLNLVVPGGNPVDVDY---RIIKGNNDNNDRKFGVDSTGRVRVIGRLDYE-IRNRYVMIVEANVSAINQIARTVVVVQVLDINDVTPKFVSDPYLASIPE----NIDIGSKVLRVFAEDLDSGSNGMVTYALVSKDKLVKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVN 2857 HSP 9 Score: 72.4034 bits (176), Expect = 8.517e-13 Identity = 128/579 (22.11%), Postives = 235/579 (40.59%), Query Frame = 3
Query: 279 VIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDID---KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDRE-KVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY---VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
V+ I ++ E P F +++KV+ ED +GS + V A S + I+Y I D F SID +G + L L D + K L V A D+ S V + + DVN+ P + +Y I E+ P + V + +D D G N ++ IQ + F +D + + + + +S+D E +V + + I D G+P L ++V ++D N+ F +S Y+ SI+ + ++ D D + + + + F + S SG I + + ++ Y + V + S + V V++ D ND+ P + V ++SF EN + + D D G + ++ S + + ++ +L + D E + + + V+++DENDN+P + L N ++ GT + A D D+ S+ LTY + +I+ TG I ++++ E Y+ F+ V D GNP+ S A++ I + +++
Sbjct: 2122 VVKIKVVDKETPVFDQLSFSKVLAEDTPIGSEVTSVTA---RSPNGAGILYS-ITGGDPVNQF-SIDFKTGVVTLVSSL-DYETRTKYKLVVRATDA--RTSSHSDVAVDVTVTDVNDVAPAFN--------------RSLYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQNVSRVGAFFKIDKKSGV--------VFVAKSLDYESRVVHEM--IIVAADEGKPSLTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSITGGQGRQHFQIDS---QSGVITLSRVVGIKQGKVYGLDVEVSDSVH-----VSTSKVRVIIGDTNDHSPIFSEDVYKVSF--NENYPEGTFVTMVSATDLDSGNYAHLTYS---------IDSVDAMRKFRIDADSGMLYSRLMFDRENSSQAIMSVPIRATDGGGRFGFCVVEVHLIDENDNQPIF----ELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVIVGHQTPPVFTINAATGVIQVSREPEVKSYNFFVLVKDGGNPLLRSIASVKITVLERD 2645 HSP 10 Score: 69.707 bits (169), Expect = 6.693e-12 Identity = 140/613 (22.84%), Postives = 256/613 (41.76%), Query Frame = 3
Query: 264 SSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDF-STSFVSIDGNSGTIILKKPLFDIDKL---TLTVEAHDSA--EHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI---QTTKLL---KNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD----------NFSILSFAVIDQDALSFNEFHLNSSNN--FNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKD-----IGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKD--IEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQS 1997
+S + I+I+D+ND +P+ + Y V E+ VG+++ V D ++G G++ Y +++ S S I+ +SG I+ KPL D + + LT++A D + + F V VN+H+P + L+ P++ E+ + + + DKD+G N +K I T K L +N + RL+ +QY L+++ + D G+P LK+ + ++V V + A F + Y +S+ EN N + + ++ + + +F + + + +SF +T EIR N D + S S V+ V + D NDN P + R++ + E + G + D K + + IS LT Y E + D+F I + + +DYE I D G P+ + +++ D ND P + + V S+ +GT++T V A D DS ++ LT+ L A+ D+ +++P TG ++++ + Y + L V+D N +A+ + I +N+ S
Sbjct: 1397 ASVPVTINILDVNDNSPQPARREYRAHVAENSDVGTLVTTVK--DPDAGVNGEVEYCIVQTAKAESASLFKIESHSGRILTVKPL-DYETMQEHVLTIKASDRGIPKRETLFSVVVSVDD---VNDHKP------------EFLS--PLFESEVDVSAKAGTAILRVIATDKDDGTNSKLKYSIVSGNTNKSLSVDQNSGVVKVAGRLSTLVHQYALKVQST-----------------DGGEPPLKTQVDVKVKVRGIVKNFA-FEKPKYEVSLPENSPPDQAIATVVYNGILPVYEIVPGRSPCWRDFTVQRQSGVIISKKSFDAEEVTHCKLEIR-ANSTDGQHS-----STLVI----------------VTIQDKNDNQPIFEHARITGHVTEGS----PQGTAVLDHKGSQLVAVATDQDISGDKLT---YEIVE--TSARDVFSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSY----AGTRVTMVTATDGDSAAN--LTFSL-ARQDTELFAVNPLTGVVTVSNAALLRRDTYTIKLTVSDG-----NHTAHARVRIRCENLPSS 1928 HSP 11 Score: 62.3882 bits (150), Expect = 9.050e-10 Identity = 132/567 (23.28%), Postives = 228/567 (40.21%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRP-------------NISVGSDKRTST-QLLNGYPIYFLEIFENNPEN-FEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENS--RISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP---EWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL 1820
D E I + + + A D P + + + +ID ND P F+ Y V+Q +A G++I + A D + G + Y LI + + SI +G +++++ L D+ TL VEA D T V+ I V+ P + +GS+ + T + NG I + I +P N F + F K G V L+ +L Y ++R + YKL +R + R S + + V V D N+ F RS Y +I E+ + ++++ ID D+ E + N + +F + + SG + + LD E ++ I +E + + T V VV++D NDN P++ M + + + P + +++ D D G+ R SI+ + + SG I+ +++ +KQ Y +H + +K+ +I+ D ND+ P E +Y S + N GT +T V A D DS + LTY +
Sbjct: 1994 DRESIDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQPVFINSPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDLIGGD---PGYFSISRKTGEVVVRRTLDDVKVPRLFTLMVEATDG------LFRTEAVVKIKVVDKETPVFDQLSFSKVLAEDTPIGSEVTSVTARSPNGAGILY-SITGGDPVNQFSIDF---------KTGVV-------TLVSSLDY-ETRTK-------YKLVVRATDARTSS------------------HSDVAVDVTVTDVNDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSGINKEINYFIQNVSRVGAFF--KIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPS--LTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSITGGQGRQHFQIDSQSG-----VITLSRVVGIKQGKVYGLDVEVSDSVHV-------STSKVRVIIG--DTNDHSPIFSEDVYKVSFNE-------NYPEGTFVTMVSATDLDSGNYAHLTYSI 2483 HSP 12 Score: 60.077 bits (144), Expect = 5.066e-9 Identity = 84/338 (24.85%), Postives = 150/338 (44.38%), Query Frame = 3
Query: 954 QPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILS-FAVIDQDALSFNEFHLNSSNNFNMES-FHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFE--MKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKIS---IIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNP 1937
QPL+ +T L N + +F + ++ I E+ +++S F D+D +N L S +++S F+++ T GE+ + PLDRE Y +I V+ + + +++ ++V + D+ND P + + +E + EN + + DKD G N I+ Y G + IS ++ V +DYE KI+I D ++ K+ +IV +LD NDN P + P + V ++ +T + A D DS + + L +ID +G I L + + + Y+L ++VTD G+P
Sbjct: 669 QPLIFATAKLH------NRHHPVFRSHDQNIHISESTPIATVVSQFMATDEDK-GYNGLVLYSIVEGDVDSVFNINMFT---GELTVAMPLDRETISSYTLNISAVDCGKH--RKSAYTILNVKITDVNDCSPVF-DKTVYEVTLPENITVGQTVTHVHASDKDQGTNGFIT--------YQIVNDFGGKFRVNRIS--GVVSVGDYLDYEEQEMYKIEIQAMDSSV--DNQKVGSTHVIVTLLDINDNSP-IVKPKKFNVTV---QEDLLVNAVVTSIHASDPDSGPGGEIEFSLPESTRKFNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSP 977 HSP 13 Score: 51.9878 bits (123), Expect = 1.601e-6 Identity = 33/84 (39.29%), Postives = 47/84 (55.95%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQP---QLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKL 437
DYE +F L + A D G P + S+ +V++I+D ND P+F A Y K + EDL G+ + V A D +SG GK+ Y L
Sbjct: 383 DYESRQRFDLTVAALD-GVPLQSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSL 465 HSP 14 Score: 49.6766 bits (117), Expect = 7.496e-6 Identity = 97/386 (25.13%), Postives = 160/386 (41.45%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT--LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP 1346
DYE K+ L + A D + S + + + D+ND AP F Y + E V + ++ V AID +SG K I I+N +F ID SG + + K L ++ + + A D + S T V + ++D N++ P DK +Y I + V+ I D DEG ++ I T + F +DS+ + T + I+Q KV + D+ + ST ++V + D N++ +F+ Y +S EN + ++ V D S N HL S + ++++ + SG + DRE S + S+ + A D F V V ++D NDN P
Sbjct: 2196 DYETRTKYKLVVRATD-ARTSSHSDVAVDVTVTDVNDVAPAFNRSLYLATISESTPVDTAVVTVKAIDGDSG-INKEINYFIQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKP-SLTGETRVRVVLMDANDNAPRF----DKS----------MYAASILGSASPGQFVTRILATDPDEGDAKKLRYSI-TGGQGRQHFQIDSQSGV--ITLSRVVGIKQG----KV---YGLDVEVSDS---VHVSTSKVRVIIGDTNDHSPIFSEDVYKVSFNENYPEGTFVTM-VSATDLDSGNYAHLTYSID-SVDAMRKFRIDADSGMLYSRLMFDRENSSQAIMSVPI--RATDGGGRFGFCVVEVHLIDENDNQP 2547
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 125.561 bits (314), Expect = 4.092e-29 Identity = 169/649 (26.04%), Postives = 279/649 (42.99%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDI-DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISV------GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPL-NFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKF--TSFATVSVVVLDINDNVPQYVGRMSFE--MKENNIPSYELGQLIFDDKDIGENSRIS--ISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP-----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHD--SISIDPFTGEI----SLTKDIEAGKYDLFLQVTDNGN-----------PMRNSSANLTIIIYQQNMFQSINSITRAVL 2024
D E + L + A D G P L + I I+D ND AP F +Y + E+ G IL+V A DR+SG G I Y + + S S +D ++G I K+ L F++ + T V A D SK D V I ++D N++ P + + DK + EN+ N +++I V DKD N + +I T + F ++ Y +++++ +DRE V P N ++N D G P + + +DV D N+ FT + Y+ +I E N S +L D D + + ++ F + SG + PLDRE+ +I AQD+ T TV+V ++D NDN P+++ + S++ + E + Q+ D D G+N RI+ ISS G LF + ++ +L K +D E + D G P+ + + + + I D NDN P + YP S ++N + KL +V A DAD ++ ++Y++ ++ + SID TG I SL ++E + L + D GN + N + NL + +Y+ F ++ + L
Sbjct: 165 DRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVP-SKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRS--------------ENSLINTNIAYILVTDKDSNTNSQTELKI-TNGDDEGCFKVEFLGF-------YFIQLQKPLDRELV--PFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDF---QSGLVTTAKPLDREQVSSVTITI----TAQDHGSAPKTGSTTVTVTIIDGNDNKPRFM-KSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNG----------LFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVF-YPVEYFASIMEN---------EPPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEE-FFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTL 759 HSP 2 Score: 121.709 bits (304), Expect = 6.342e-28 Identity = 139/543 (25.60%), Postives = 229/543 (42.17%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFST----SFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKN-LFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPAL------------FTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP-----QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS---ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKA 1826
+ + DIND P+F YT ++E + V + A D ++G+ G + Y + ++ +T + G++ +I KKPL D L + A D + + + I I+D N+H P + S Y I EN + ++ D+D G NGD+K I + N +F LDS + +R +Q++D E V N F++ D G P + ++VLD N+ P L RS SL N +I V D+D+ + ++ L +N + F + L I++ PLDRE P Y ++ V ++ + F + V D+NDN P Y +S E+ +N SY L QL D D G+N +S S ++G DL W + ++ + +D E + + I I D G ++ V I+D NDN+P ++ S + + I G + +V A D DS + R+TYE+ +
Sbjct: 83 VQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTP-ALMGYCLINITILDENDHAPVFTQNS--------------YLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGV--------IRTKQNLDFE-VKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLI------NTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFL--GFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVT--DVNDNSPAFTSNAYTANIS-ELAQNG--SYVL-QLNATDPDEGDNGTVSYS------------ITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASI----GATVLQVSATDVDSGDNGRITYEISS 571 HSP 3 Score: 119.013 bits (297), Expect = 4.552e-27 Identity = 145/629 (23.05%), Postives = 264/629 (41.97%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDK--LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPI-YFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN--------------KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFD----DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTG-----EISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQSI 2000
D E + + + A D G S + + IID ND P+F+ +Y + E ++G+ +L+V A D +SGD G+I Y++ ++ ++ +G + K L K + TV A D + V + I D+N++ P YP+ YF I EN P ++ + D DEG N + I N F +DS + + S+D E V + I+ +D G T ++ V VL++ + +F Y+ ++ EN KD +S+A++ D N F ++S + G I+I +DRE+ + Q+ + V+ ++ ATV++ VLD NDN PQ+ + ++ +GQ++++ D D G+N + + S E L WI S ++++ + + + + D G P H+ ++I + + ++ P++ S + +V+ ++ Q V A+D DS + +L Y + ++ F G SL + ++ G YDL ++ TD G P ++S +TI I N +S+
Sbjct: 489 DREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQ-LMSSVKVELTISDINDNAPVF---------------YPVEYFASIMENEPPG-KLLQVTATDADEGTNAVISYDIIGGNNNGN-FSIDSSTGV--------ISTLASLDHE-VEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKDKNGSISYAIVSGDPT--NLFLVDS----------------TGGIIKINGDMDREE--KAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDG---TWLVGQVVYNAAAVDLDAGKNGLVRY-----------QLTSNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITL--SINHPPKFTLSSYVTHVLASQPLSYQ----FFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIFPGGKLYIRKSLLQALK-GSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSL 1049 HSP 4 Score: 100.138 bits (248), Expect = 2.866e-21 Identity = 145/617 (23.50%), Postives = 267/617 (43.27%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLV-IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVE--AHDSAEHNSKFDWT-HVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAV---IDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQ----DNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYE-----LKAKHDSISIDPFTGEISLTK--DIEAGK-YDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
D E +++L +IA +G + S+Q V I+++D ND AP+F + + VG V+ A+D ++G G + Y+L N + + I+ SG I L + L D D+ TV+ A DS T H+ + I NH P ++ S Y + + P +++ ++ VD+D GKNG + I + LF + KL IR+S+ + + + + D G P +++ + + + D N++ +LF + + ++ EN +++ V +D + L SS + H ++ SG+I LDRE+ + S + +A+ D T A V V V D+NDN P + + + + E ++P + ++ D D G+N++ S ++ T G + F S L + +++D E + + + D ++ I + + D ND P ++P S D VNI+ + G+ + + A D D + + Y L A D ++ TG + + K D E + Y+L + D+G +S+ N+T+ + N
Sbjct: 803 DREEKAQYLLAVIA-RVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAE---GLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLSI----NHPPKFTLSS--------------YVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNE-EGLFGIFPGG---------KLYIRKSL-LQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSES------HF-AVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGT---------GMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRP--VFPES-DYTVNITE-DALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFD---VESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVN 1363 HSP 5 Score: 95.9005 bits (237), Expect = 5.567e-20 Identity = 145/594 (24.41%), Postives = 249/594 (41.92%), Query Frame = 3
Query: 276 LVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT-----LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSP--RYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI--SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDEN--DNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELK--AKHDSISIDPFTGEISLTKDIE----AGKYDLFLQVTDNGNP-MRNSSANLTIIIYQQN 1985
+++ + D+ND AP F Y V E GS + ++ A+D + GD K Y L+ F I+ ++G + L K L D+ T L V+A D++ N + + I + D N+ RP + SD Y + I E+ V +N DKD G+NG +K I L +F ++S +L + +S+D E + +I QD+G L ST+ + V+VLD N+ LF +L++ EN + F + D+D ++F+ + S F++ S ++ EI +D E P R F + V+ Q + K ++ +++V V D NDN P +V + S + + +D D N +++ S +SGN F + S ++ + Q D I+ ++ I D G P + +V++ E P + SS D +++ N +GT + V A S + + Y L + + TG + T+ I+ ++L + D P R SSA +TI + N
Sbjct: 1145 VIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFF--INSSTGELHLSKTL---DRETTSSYNLVVKATDASNAN-LYSTAKIEITVGDSNDQRP-VFPESD-------------YTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAA-MFDVESATG--------RLIVAKSLDFE-TTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNS--------ATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAAAGS----SLNVMTITAEDPDRNSNGKVTYS-----------IISGNNGYFNLHPSTGQLQMIHQIPDNPTIY--QLTIQASDGGQPSRQTQ--TVVSVFKEGPIGGGPTF---SSADYQGSVTE-NKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 HSP 6 Score: 64.3142 bits (155), Expect = 2.147e-10 Identity = 68/279 (24.37%), Postives = 120/279 (43.01%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDIDK---LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVS---NPLNFSINCQDNGQPLLKSTIILQVDVLDQNE 1010
D E + L + A D L S+ K+ I + D ND+ P F +YT + ED +GS+++ ++A D++ G G I Y I N + + F ++ +G +I+ K L F+ + LT+T + H +S +V + ++DVN++ P L P+ L + EN F V D+D G N + + + K + N+ ++ +ID E + + + D G P L + + V V D+N+
Sbjct: 1223 DRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYS-ISNGNLAAMF-DVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTV---NVTVNVLDVNDNAP-------------LFPTQPVT-LTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKT---------FSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDEND 1473
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 182.57 bits (462), Expect = 1.346e-46 Identity = 174/609 (28.57%), Postives = 278/609 (45.65%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISV-GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSII-ENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSS-----LDNVVNI-SHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + A D G PQ S L + + D ND +PKF +Y V E+ VG +L+V A D + G G+I Y L + D + ID +G I +K PL +I+ L+ V A D K T V I + D N++ P + + G T ++ + I E+ P V+ + V DKDEG+N V C + + DS + N +Y L+ +D E+V I D+G P L ST L+V V D N+ +F+ + + + EN+ +IL D D+ + E N + ++ L + ++GE++ PLDRE RY+F + ++ K T ATV + VLD NDN P+++ SF + EN P +G + D D GEN+ + +S + G + + IL S D E + + D G P + + + +N+LDENDN+P PS+ L V + SH+++ V A D DS + L + + + I P +GEI+L K++ G + L ++V+D G P R+++A + I +
Sbjct: 280 DRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEINSLSFYVVARDKGPQ-PKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGI-------ANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDS---TSDNKRKYFLQTTTPLDYERVKE-YRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKG--LFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGT--ATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSV----------EPDGGKFVVQNGTGTILS-SISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNSSFRQLSPVASPDSHVDV--------VEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYV 853 HSP 2 Score: 99.3673 bits (246), Expect = 9.359e-21 Identity = 133/607 (21.91%), Postives = 243/607 (40.03%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFV--SIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTR---------------------SNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I++ DIND P+F T V E+ +G++ A DR+S G Y L D +T F D G + L ++D+ LT++A D + ++ + + + D N++ P +P Y E+ EN+P V + D D G NG+++ + Q + L +D + + ++ +DRE++ N L+F + +D G S + ++V DQN+ PA+ R + +L + +KD + + F + S + N + L + T PLD E+ Y+ I V+ N +S ++ V V D+NDN P + + + E N P + + D D G N+ + ++ Y + G LF I ++ + +D E + + D+G P + ++++ +LD NDN+P+++ S L+N+ +S + + V +D D + + ++ + TG I S++ D E Y L+ D G P R+S +TI + +N
Sbjct: 197 IEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGG-NPQRYSQALLRVVVTDANDNSPKFE--------------HPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGI--------IYVKGPLDREEI-NSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTTT----------PLDYERVKEYRVEIVAVDSG--NPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAEL-FYNIVGDSY-----IKG---LFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGM--------VTVLDMDKGENAHVHLSVEPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDEN 750
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 181.03 bits (458), Expect = 2.797e-46 Identity = 174/609 (28.57%), Postives = 278/609 (45.65%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISV-GSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSII-ENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSS-----LDNVVNI-SHINIQSGTKLTRVRAIDADSVSSNRLTYELKA--KHDSISIDPFTGEISLTKDI---EAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
D E + L + A D G PQ S L + + D ND +PKF +Y V E+ VG +L+V A D + G G+I Y L + D + ID +G I +K PL +I+ L+ V A D K T V I + D N++ P + + G T ++ + I E+ P V+ + V DKDEG+N V C + + DS + N +Y L+ +D E+V I D+G P L ST L+V V D N+ +F+ + + + EN+ +IL D D+ + E N + ++ L + ++GE++ PLDRE RY+F + ++ K T ATV + VLD NDN P+++ SF + EN P +G + D D GEN+ + +S + G + + IL S D E + + D G P + + + +N+LDENDN+P PS+ L V + SH+++ V A D DS + L + + + I P +GEI+L K++ G + L ++V+D G P R+++A + I +
Sbjct: 203 DRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEINSLSFYVVARDKGPQ-PKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGI-------ANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDS---TSDNKRKYFLQTTTPLDYERVKE-YRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKG--LFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGT--ATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSV----------EPDGGKFVVQNGTGTILS-SISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKPSNSSFRQLSPVASPDSHVDV--------VEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYV 776 HSP 2 Score: 98.5969 bits (244), Expect = 1.776e-20 Identity = 132/597 (22.11%), Postives = 246/597 (41.21%), Query Frame = 3
Query: 282 IDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFV--SIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQI-QTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YPALFTRS----NYSLSIIENKDNFSI-LSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGE------IRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYP----SSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN 1985
I++ DIND P+F T V E+ +G++ A DR+S G Y L D +T F D G + L ++D+ LT++A D + ++ + + + D N++ P +P Y E+ EN+P V + D D G NG+++ + Q + L +D + + ++ +DRE++ N L+F + +D G S + ++V DQN+ PA+ R +S I ++ + + A++ E + + F L + S+ + ++ PLD E+ Y+ I V+ N +S ++ V V D+NDN P + + + E N P + + D D G N+ + ++ Y + G LF I ++ + +D E + + D+G P + ++++ +LD NDN+P+++ S L+N+ +S + + V +D D + + ++ + TG I S++ D E Y L+ D G P R+S +TI + +N
Sbjct: 120 IEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGG-NPQRYSQALLRVVVTDANDNSPKFE--------------HPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGI--------IYVKGPLDREEI-NSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTTTPLDYERVKEYRVEIVAVDSG--NPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAEL-FYNIVGDSY-----IKG---LFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGM--------VTVLDMDKGENAHVHLSVEPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVGVTINVLDEN 673
BLAST of Protocadherin vs. Ensembl Medaka
Match: fat2 (FAT atypical cadherin 2 [Source:NCBI gene;Acc:101170600]) HSP 1 Score: 162.155 bits (409), Expect = 7.525e-40 Identity = 152/602 (25.25%), Postives = 274/602 (45.51%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSK-FDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPL-NFSINCQDNGQPL-LKSTIILQVDVLDQNE--YPALFTRSNYSLSIIENKD-NFSILSFAVIDQDAL--SFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSY-ELGQLIFDDKDIGENSRISISSLTT-TCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHI--NIQSGTK-LTRVRAIDADSVSSNRLTYELKAKHDS-ISIDPFTGEISLTKDIEAGKYDLF-LQVTDNGNPMRNSSANLTI 1967
++L + A D+G PQ + + ++I+D+ND P F Y V E+ AVGSV+ A D ++ GK+ Y L+ ST +D +G +I+ L D + + L ++A D A+H + F ++I + D+N++ P P Y +++ E+ P + ++ +D D G+ G V +++T+ +F N L + + +D E+ P+ N ++ D+G P L S+ +++ VLD NE Y F+ Y ++IE+ S+++ D+D +H++ + + ++ + SG IR LDRE P Y S+F + + S+ V + VLD+NDN PQ + F + N+ + QL D D+ ++S L + Y + +G ++ ++D E I++ D P + ++++ +LD NDN P++ D + ++ + QSG + + RV A D D S+ +TY+L+ D IDP TG ++ D G Y + ++ TD G+P R+S+ L I
Sbjct: 777 YILNITAYDLGMPQRSVWKLMAVNILDVNDNPPMFDQPRYVIRVPENTAVGSVVFTAQAADMDTDMSGKVQYLLLT----STDLFRVDELTGEVIVTGQL-DREAVASHNLWIQARDQAKHGPQLFSTISLLIILQDINDNPPRFVP--------------PGYRIKVAEDVPVGTILLWVESIDLDLGRAGLVSYNLKSTE--SGIF--------NIEPSTGALTLERELDFER--RPMYNLTVRAVDHGLPRSLSSSCFVEIQVLDVNENLYRPTFSEFVYEAAVIEDAAVGSSVVTLTASDKDLGRDGVVRYHIHDGSGLG-----VFTIDEESGVIRTSELLDRETVPHYWLSVFATDLGTE--PLVSWTHVFLEVLDVNDNAPQLSQPIYFASVQENVEKVNSVIQLSATDVDVSSEGKLSFQMLESHRVYFDIDPKTG-----------VISTLAALDREEKPEHSIEVVVSDNAAPALRSTATVVIKVLDSNDNRPKFT-----DKLFHVQLLERRWQSGKRDVCRVVASDEDEGSNAVVTYKLQDNSDERFQIDPLTGVVTSHGDFWPGNYSILTIKATDGGSPPRSSTTRLDI 1324 HSP 2 Score: 104.375 bits (259), Expect = 3.824e-22 Identity = 135/612 (22.06%), Postives = 272/612 (44.44%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVE--AHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVV--DKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFS---INCQDNGQPLLKSTIILQVD---VLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVID--QDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRM-SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKH-DSI-SIDPFTGEISLTKDIEAGKYDLF---LQVTDNGNPMRNSSANLTIII 1973
D E +P + L + A D+G L S + ++++D+ND AP+ Y VQE++ + ++++ A D + GK+ ++++++ + ID +G I L +K ++E D+A + T VVI ++D N++RP +DK ++ +++ E ++ + VV D+DEG N V ++Q D R +++ T + P N+S I D G P ST L ++ V + P F +++ +++E + +++ +++ + L F+ + +F+++ ++SG I I LD + Y ++ V + + T + VLDIN++ P ++ + + E+ P ++ Q+ D D SI S P + LF + + +L + + +D+E + + D+ P N +++++ D ND+ P ++ P ++ N +G+++ RV+A+D D+ S+ ++Y L + + D+I SID +G I ++K + D F ++ TD G P R+ L + I
Sbjct: 1087 DRETVPHYWLSVFATDLGTEPLVSWTHVFLEVLDVNDNAPQLSQPIYFASVQENVEKVNSVIQLSATDVDVSSEGKLSFQMLESHRV---YFDIDPKTGVISTLAALDREEKPEHSIEVVVSDNAAPALRSTAT-VVIKVLDSNDNRPKF---TDK-----------LFHVQLLERRWQSGKRDVCRVVASDEDEGSNAVVTYKLQDNS--------DERFQIDPLT--------GVVTSHGDFWPGNYSILTIKATDGGSPPRSSTTRLDIEWVAVPPPSADPITFEEPHFTFAVMETEPVTNMVGVIMMETQRQRLWFDITGGDEDKDFDIQ--------KNSGTITIARKLDAARHAIYNLTVQVTDGHRSAT-----TQAYIRVLDINEHRPVFLKPLYEVSIPEDTSPWKDILQISAQDLDSNSKLVFSIHSAV-----PPDSTG----LFHLDPKSGVLVMTEPLDFERTAVHTLVVMVRDQEIPMKRNFAKVVIHVEDCNDHSPAFLSPRYEASISN----QAPTGSEVIRVKALDKDTGSNADISYSLHSGNTDNIFSIDAESGSIRVSKPLGLQHQDHFHLSVKATDQGFPQRSDLCTLHLHI 1638 HSP 3 Score: 103.219 bits (256), Expect = 9.554e-22 Identity = 98/364 (26.92%), Postives = 175/364 (48.08%), Query Frame = 3
Query: 210 PKFVLQLIACDIGQP-QLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIK-NEDFSTSFVSIDGNSGTIILKKPL-FDIDK-LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFN---EFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQ 1277
P FVL++ A D G P QL S+ + +D++ ++D P F++ +YT + E LAVGS +L V A+ + G I+Y++I NED F+ +D ++G + L PL F++ + L+VE S + D T ++I + DVN++ P + SD+ ++I E+ V + D+D N ++ I + L+ F +D R ++ +R ++DRE+ + + ++ D G P L S ++ + V D N+ P +F++ N+ L + E + +IL V+D+D FH+ S N FH+ G + + PL ++ +Q I V +
Sbjct: 3174 PTFVLKVKATDRGLPRQLYSTATVTVDVVSLDDYQPVFLSSDYTAQLPESLAVGSEVLSVSALTADGGGPDAIVYRIISGNED--GRFL-LDAHTGLLTLMAPLDFEVSREYFLSVEG--SRGKSPLKDITTIIINVTDVNDNAP-VFRQSDRS-------------VDISEDLTPGSLVMKVTATDQDGPINNLLRYSIVSGDPLQQ-FSIDHR--------SGEITVRTALDREQTPH-YSLTVQAADEGSPPLSSAALITITVSDVNDNPPVFSQVNHHLLLQEGEAVGSTILQLVVMDRDMPKNGPPFSFHIVSGN--EDRRFHV----DQGGLLSLSAPLRKKVKAHHQLKIQVTDSGH 3502 HSP 4 Score: 101.293 bits (251), Expect = 3.646e-21 Identity = 151/609 (24.79%), Postives = 267/609 (43.84%), Query Frame = 3
Query: 276 LVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FDI-DKL-TLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNIS-VGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNG-QPLLKS--TII--LQVDVLDQNEYPALFTRSNYSLS---------------------IIENKD-NFSILSFAVIDQDALSFNE---FHLNSSNN---FNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFD----DKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKI-LQVKQSMDYEFI--HNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSI-SIDPFTGEISLTKDIEAGK---YDLFLQVTDNGNPMRNSSA 1955
LV++I D ND +P F +Y + E+ VGS ++KV A D + G G + Y + ++ +ID +G I+ + L F++ ++L L V A DS S+ V I + ++N++ P VG + L G + L F+++ E ++ +I E N + Q+ + +L + + ++ +++ + R + S + +D G +P L T I Q D L ++ P L + S S ++EN N +IL F D D+ FN F L+S N F +++F SGE+R+ LDRE Y +I + + + + ++V +LD+NDN P + R + EN +G ++F D D + ++ LT+T DLF + EL + V +D E + HN I + P+ + IS+++ + D NDN P ++ P V ++ GT L V +ID D + ++Y LK+ I +I+P TG ++L ++++ + Y+L ++ D+G P SS+
Sbjct: 442 LVVEITDENDNSPLFTQTSYQATLDENTPVGSSVVKVTAWDSDKGKNGFVTYSIAHSDPLP---FTIDPFTGVILTSEHLDFELANRLYHLRVWASDSGSPFSQVSECPVTITLNNINDNFPVFERVGCNITVPLDLPVGREVAKLSAFDSD-ELEQLQYII-----ESGN---ELQVFGMETFSGALFLKKPIPPQEGSFTFRVVVSDGKHRSEAS---VVRVTVRDKGDKPTLHCLETGIQKQQTDKLIESMKPVLVNKKEESFSDQHITNRHTPKFVKSVPSSIDVVENHPLNSTILQFKAADGDS-GFNGQVVFALSSGNEDGCFCIDTF--------SGELRLVCSLDRESKEFYILNITAYDLGM--PQRSVWKLMAVNILDVNDNPPMFDQPRYVIRVPENT----AVGSVVFTAQAADMDTDMSGKVQYLLLTST------------DLFRVDELTGEVIVTGQLDREAVASHNLWIQARDQAKHGPQLFSTISLLIILQDINDNPPRFVPPGYRIKVAE----DVPVGTILLWVESIDLDLGRAGLVSYNLKSTESGIFNIEPSTGALTLERELDFERRPMYNLTVRAVDHGLPRSLSSS 1004 HSP 5 Score: 89.7373 bits (221), Expect = 1.325e-17 Identity = 136/590 (23.05%), Postives = 251/590 (42.54%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLT--LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVG-RMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPT---EKLSGNEDL-FWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNV-VNISHINIQSGTK-LTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKDIEAGKYDLFLQVTDN 1928
D E +F L A D G + +L++ D+ND P F A +Y V ++ V + + ++A D ++G ++ Y LI + + S+D SG + L++PL T L V+A D + V + ++ +++++P + + SD Y ++ E+ EV ++ + D G + +I + F LD+ L L + +D E VS S+ PL T I+ ++V D N+ +F +S+ S+ I E+ S ++ DQD N + + ++ F S+ SGEI + LDRE++P Y ++ +E + +S A +++ V D+NDN P + ++E + QL+ D+D+ +N GP +SGNED F + + +L + + + + ++ I D G P + + +N+ +++ YP ++ + V I+ Q + + V A D D + L Y+L + SID G++ +E G Y L + V+D
Sbjct: 3067 DRESDGEFNLVAKATDGGGRSCQADIQLMVQ--DMNDNQPLFSASHYMVTVFDNTTVRTPVAVIYAKDPDAGINSEVRYSLIAGD---AGYFSLDEFSGVLRLERPLTPDTPPTFVLKVKATDRGLPRQLYSTATVTVDVVSLDDYQP-VFLSSD-------------YTAQLPESLAVGSEVLSVSALTADGGGPDAIVYRIISGNE-DGRFLLDAHTGL--------LTLMAPLDFE-VSREYFLSVEGSRGKSPLKDITTII-INVTDVNDNAPVFRQSDRSVDISEDLTPGSLVMKVTATDQDGPINNLLRYSIVSGDPLQQF---SIDHRSGEITVRTALDREQTPHYSLTVQAADEG--SPPLSSAALITITVSDVNDNPPVFSQVNHHLLLQEGEAVGSTILQLVVMDRDMPKN-------------GPPFSFHIVSGNEDRRFHVDQGGLLSLSAPLRKKVKAHHQLKIQVTDSGHPPLSSICVVNINVTEQSK------YPPTVTPLEVFITTTGGQFPNRVIGWVHAADQDL--QDVLIYKLVTPDNGNKFSIDANNGKLCAEGTLEDGTYALNVSVSDG 3600 HSP 6 Score: 88.9669 bits (219), Expect = 1.939e-17 Identity = 148/620 (23.87%), Postives = 245/620 (39.52%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKN--EDFSTSFVSIDGNSGTIILKKPLFDIDKL---TLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPI-YFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDA-----LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISEL-----KILQ-----VKQSMDYEFIHN--CKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWI---YPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL----KAKHDSISIDPFTGEISLTKDIEAGKYDLF---LQVTDNGNPMRNSS 1952
D+E + K+VL ++A D G+P L + +L I + N P F Y V E++ + IL V A + E Y+LI N E+ ++ +D +G + + PL D + TLTV A D+ F + + + DVN++ P S P+ Y I E P N V+ ++ DKD G+N D+ I TT D N + R+ +D E+ + DNG L S + +++ D N+ P F S + + E + ++ D D+ L + N FN + +SSG I N R P Y ++ V +D V Q ++ +M +N S Q ++ + ++ EN++ + P E G+ D I++L IL+ Q +D E I + D G + II+ DENDN P++ Y S+ + VN G+ + +V A DAD + +TY + + D I I+PFTG +S+ + + + +F ++ D P NS+
Sbjct: 2120 DFEALNKYVLTVLATDEGEPGLSTVSQLSIQV--RNQSNPIFQTLLYPLKVPENVPPFTTILHVQARNPEG-------YRLIYNLEEENASRHFHVDFKTGVLTVTNPL-DYESQTAHTLTVRATDAV--TGSFSEATIEVEVEDVNDNAPVFS---------------PLTYAANIAERLPVNTSVTRVSASDKDSGRNKDLTYAIVTTG-------EDDADSFEINQKTGLIVTRKVLDYEERKQ-FKLKVRATDNGSVPLSSEAFVTINITDVNDNPPDFISSEFKAKVDETANCGHLVVKIQASDPDSADTKNLKYKILTGNRDRYFN--------INESSGVISFSNVCKRNLDPFYNLTVAV-----------------------SDGVFQKTAPVTIDMINSNRYSPYFKQSVY-EAELAENAQAGTRVIRLAAIDPDEGPYGSVDYTIINKLADEKFAILKDGQIITTQPLDRENSTQKVVAIKVMAKDGGGRVAFCTVKIILT--DENDNVPQFKASEYQVSIQSTVN-------KGSPVIQVMAYDADDGKNADVTYTVDEAEEVTEDIIEINPFTGVVSVKESLVGMENRIFNFKVKARDGSLPFYNST 2663 HSP 7 Score: 88.5817 bits (218), Expect = 2.910e-17 Identity = 137/578 (23.70%), Postives = 238/578 (41.18%), Query Frame = 3
Query: 312 PKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKN---EDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSK--FDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPL-LKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNF-SILSFAVIDQD-ALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFE-MKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGP-TEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS-ISIDPFTGEISLTKDIEAGKYDLF---LQVTDNGNPMR-NSSANLTIIIYQQNMFQSI 2000
PKF Y+ ED +GS I V R D +IY L+ E S+D SGT++L+KP+ ++ HN V I + DVN+++P + + P Y + EN P V + D D NG V ++ L + LD + + + + +D E+ S F++ D+G + L S++ ++V V D+N+ P F+ Y S++EN F I+S D D AL ++ + F + ++ + + LDRE R+ + + KF + TV + VLD+NDN P + E + EN+ P L ++ D D+G N IS T +GP +K + + L +L + ++ + D G I ++V D NDN+P ++ +S V + ++ T + + A D D+ ++ + Y L A S+D F+G + L + + F ++ TD G P + S+A +T+ + + +Q +
Sbjct: 2678 PKFSEPLYSFSAAEDFPIGSEIGSV----RADSDM-PLIYSLVNGNTVESNKDKVFSLDKESGTLLLQKPIDHERTKWYQIDVIAQGNHNGTDVASLVSVSIQVQDVNDNQP-------------VFDASP-YRAFLTENMPAGTTVIQVTANDPDTDTNGLVTYSLEP---LADGAQLDISQVFSIDGDSGWITTLREVDCER-SRMFRFNVVATDHGGEVKLSSSVRVEVMVTDENDNPPTFSEEVYRGSVVENITPFEPIVSMTTFDADVALQNRLVTCYITDGDPLGQFAIIQEDENQWGLIVKESLDRETKDRFTLRVTAT-----DGKFEAAVTVEIHVLDLNDNSPTCEQLLYTETVMENSSPRRFLLKVSASDPDVGANGEISY-----TLHGPDADKFHLDHRTGELLTLAVLDRESDGEFNLVAKAT------DGGGRSCQADIQLMVQ--DMNDNQP--LFSASHYMVTVFDNTTVR--TPVAVIYAKDPDAGINSEVRYSLIAGDAGYFSLDEFSGVLRLERPLTPDTPPTFVLKVKATDRGLPRQLYSTATVTVDVVSLDDYQPV 3210 HSP 8 Score: 75.0998 bits (183), Expect = 3.328e-13 Identity = 114/510 (22.35%), Postives = 212/510 (41.57%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDID---KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNF--SINCQDNGQPL-LKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVI-----DQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEP 1685
D E +F L++ A D + ++ + I ++D+ND +P YT+ V E+ + +LKV A D + G G+I Y L + +D +G +L + D + + L +A D + + D + + + D+N+++P S Y + +F+N V+ I D D G N +V+ + F LD + LR+ + + + P F + D G P L ST + VDV+ ++Y +F S+Y+ + E+ S +LS + + DA+ + N F +++ +G + + PLD E S Y S V ++ + T+ + V D+NDN P + S ++ E+ P + ++ D+D N+ + S ++ P ++ S + I+ V+ ++D E + + + DEG P + I + + D NDN P
Sbjct: 2966 DRETKDRFTLRVTATD---GKFEAAVTVEIHVLDLNDNSPTCEQLLYTETVMENSSPRRFLLKVSASDPDVGANGEISYTLHGPD---ADKFHLDHRTGE-LLTLAVLDRESDGEFNLVAKATDGGGRSCQAD---IQLMVQDMNDNQPLFSASH--------------YMVTVFDNTTVRTPVAVIYAKDPDAGINSEVRYSLIAGD--AGYFSLDE--------FSGVLRLERPLTPD---TPPTFVLKVKATDRGLPRQLYSTATVTVDVVSLDDYQPVFLSSDYTAQLPESLAVGSEVLSVSALTADGGGPDAIVYRIISGNEDGRFLLDAH--------TGLLTLMAPLDFEVSREYFLS---VEGSRGKSPLKDITTIIINVTDVNDNAPVFRQSDRSVDISEDLTPGSLVMKVTATDQDGPINNLLRYSIVSGD---PLQQFSIDHRSGEIT------VRTALDREQTPHYSLTVQAADEGSPPLSSAALITITVSDVNDNPP 3418 HSP 9 Score: 74.3294 bits (181), Expect = 6.769e-13 Identity = 97/424 (22.88%), Postives = 184/424 (43.40%), Query Frame = 3
Query: 588 THVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSF-INVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDA--LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVP-----QYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISE-LKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWI---YPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL 1820
T V +FI DVN++ P Q LN + F + + E +V + +D D+G+NG + I + + F++D + + +++ +D E + N ++ D G+P L + L + V +Q+ +F Y L + EN F+ IL + + L +N N+S +F+++ +G + + NPLD E + ++ + T S AT+ V V D+NDN P Y ++ + N + ++ DKD G N ++ + +TT + D F I++ ++ ++ +DYE K+ + D G ++ + +NI D NDN P++I + + +D N H+ + +++A D DS + L Y++
Sbjct: 2042 TQVKVFIDDVNDNSP------------QFLN---LPFSMMISEDSEPGDVLYQATAIDSDQGENGSI---IYSLVEDFDFFWIDPDVG--------DISLKKPLDFEAL-NKYVLTVLATDEGEPGLSTVSQLSIQVRNQSN--PIFQTLLYPLKVPENVPPFTTILHVQARNPEGYRLIYNLEEENASRHFHVDF--------KTGVLTVTNPLDYESQTAHTLTVRATDAV---TGSFSEATIEVEVEDVNDNAPVFSPLTYAANIAERLPVNT----SVTRVSASDKDSGRNKDLTYAIVTTG--------EDDADSFEINQKTGLIVTRKVLDYEERKQFKLKVRATDNGSVPLSSEAFVTINITDVNDNPPDFISSEFKAKVDETANCGHL-------VVKIQASDPDSADTKNLKYKI 2406 HSP 10 Score: 72.7886 bits (177), Expect = 1.630e-12 Identity = 132/549 (24.04%), Postives = 230/549 (41.89%), Query Frame = 3
Query: 240 DIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL-FD-IDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDRE-KVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIF----DDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFW-ISELKILQVKQSMDYEFIHNCK--------IDIHFHDEGFPKNHNKISIIVNILDENDNEP---EWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL 1820
D+ P ++ ++ + I D+ND +P+F+ ++ ++ ED G V+ + AID + G+ G IIY L+ EDF F ID + G I LKKPL F+ ++K LTV A D E + V I V N I Q L +Y L++ EN P + + + EG +L+ NL ++ + + L + +D E + ++ L G S ++V+V D N+ +F+ Y+ +I E N S+ + D+D+ + + + ++ + +SF ++ Q +G I LD E+ R QF + V + +S A V++ + D+NDN P ++ S E K + G L+ D D + + LT GN D ++ I+E S F + CK + + D F K + +++++ N P + +Y + L N Q+GT++ R+ AID D + Y +
Sbjct: 2032 DMRDPPRTATTQVKVFIDDVNDNSPQFLNLPFSMMISEDSEPGDVLYQATAIDSDQGENGSIIYSLV--EDF--DFFWIDPDVGDISLKKPLDFEALNKYVLTVLATDEGEPG----LSTVSQLSIQVRNQSNPI---------FQTL----LYPLKVPENVPPFTTILHVQARNP-EGY-----------RLIYNLEEENASRHFHVDFKTGVLTVTNPLDYESQTAHTLTVRATDAVTGS---FSEATIEVEVEDVNDNAPVFSPLTYAANIAERLPVNTSVTRVSASDKDSGRNKDLTYAIVTTGEDDADSFEIN---QKTGLIVTRKVLDYEE--RKQFKLKVRATDNGSVPLSSEAFVTINITDVNDNPPDFI---SSEFKAKVDETANCGHLVVKIQASDPDSADTKNLKYKILT-----------GNRDRYFNINE-------SSGVISFSNVCKRNLDPFYNLTVAVSDGVFQKT---APVTIDMINSNRYSPYFKQSVYEAELAE-------NAQAGTRVIRLAAIDPDEGPYGSVDYTI 2508 HSP 11 Score: 70.4774 bits (171), Expect = 1.028e-11 Identity = 125/561 (22.28%), Postives = 229/561 (40.82%), Query Frame = 3
Query: 222 LQLIACDIGQP-QLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDID-KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNI---SVGSDKRTSTQLLNGY-PIYF---------------------------LEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSIL---SFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIF----DDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWI-SELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISII-VNILDENDN--EP---EWIYPSSL--DNVVNISHINIQSGTK 1757
L++ A D G P S + I + +IND P F V DL VG + K+ A D S + ++ Y + + ++ SG + LKKP+ + T V D +H S+ VV + +P + G K+ + +L+ P+ +++ EN+P N + D D G NG V + + F +D T+ +LR+ S+DRE + +I D G P ++ V++LD N+ P +F + Y + + EN S++ A +D D ++ L +S + F + LT GE+ + LDRE + I ++A+ + S ++ +++ DINDN P++V ++P +G ++ D D+G +S +L +T G +F I L +++ +D+E + + D G P++ + + + +LD N+N P E++Y +++ D V S + + + K
Sbjct: 529 LRVWASDSGSPFSQVSECPVTITLNNINDNFPVFERVGCNITVPLDLPVGREVAKLSAFD--SDELEQLQYIIESGNELQV--FGMETFSGALFLKKPIPPQEGSFTFRVVVSD-GKHRSE---ASVVRVTVRDKGDKPTLHCLETGIQKQQTDKLIESMKPVLVNKKEESFSDQHITNRHTPKFVKSVPSSIDVVENHPLNSTILQFKAADGDSGFNGQVVFALSSGN-EDGCFCID--------TFSGELRLVCSLDRESKEFYI-LNITAYDLGMPQRSVWKLMAVNILDVNDNPPMFDQPRYVIRVPENTAVGSVVFTAQAADMDTDMSGKVQYLLLTSTDL----FRVDELT---GEVIVTGQLDREAVASHNLWIQARDQAKHGPQLFSTISLLIILQDINDNPPRFVPPGYRIKVAEDVP---VGTILLWVESIDLDLGRAGLVSY-NLKSTESG----------IFNIEPSTGALTLERELDFERRPMYNLTVRAVDHGLPRSLSSSCFVEIQVLDVNENLYRPTFSEFVYEAAVIEDAAVGSSVVTLTASDK 1050 HSP 12 Score: 55.8398 bits (133), Expect = 2.983e-7 Identity = 148/621 (23.83%), Postives = 254/621 (40.90%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPL--FDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDV--LDQNEYPALFTRSNYSLSII--ENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSG---NEDLFW-----ISELKILQVKQ-------SMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTK--DIEA-GKYDLFLQVTDNGNPMRNSSANLTIIIYQQN--MFQSI 2000
F L + A D G PQ L + I + P F + Y + E A G+ ++ V A + +G I++ + + +F ++ +G I ++K L D + L V A +A SK T V I++ID N++ P + + + + ++N ++ D D G N + QI + L+ +F +D M + + ++D E + +F++ +D+G+ L++ +V V LD N+ F S+I +D + A D A+S++ N F S+ ++G I + N D + P YQ + A D + A V V V ++ D+ Q+ R+ Y G + EN + ++ +L K+SG NE L + + + KI Q + D E I + D P + V I D NDN P+++ +L + IS + + G L + AID+D + + Y L D IDP G+ISL K D EA KY L + TD G P ++ + L+I + Q+ +FQ++
Sbjct: 1614 FHLSVKATDQGFPQRSDLCTLHLHIRLSDRTPPTFSSDEYLTEISELSAPGTPVVTVSASSPAAVHYG------IESGNTNGTFY-LNPYTGLISIQKHLDFEDHESYRLEVAASTTAGALSK---TFVSIYVIDENDNAPRFQ---QSEYQGHISESAHVNSMVMGQSNAP----LVVHASDADRGFNSLLTYQILEPEALR-VFQIDPSMG--------TISLVSAVDFEAKAE-YHFTVQVKDSGELSLRAAKPAKVTVRILDLNDCAPQFATPVLQSSVIWPAVRDAEVVRVTARDDDSAVSYSITEGNLHQAF--------SIHPNTGVISVSNVTDFQ--PFYQLLV----RASDGL-YKDSAVVKVNVTNLTDSDLQFQQRV-----------YSAG--------VSENLK-AVQTLAAL------KVSGCFLNEPLLYSIINPMGKFKISQTSGVLETTGVAFDREEQDVYDITVKVQDMRDPPRTATTQVKVFIDDVNDNSPQFL---NLPFSMMISE-DSEPGDVLYQATAIDSDQGENGSIIYSLVEDFDFFWIDPDVGDISLKKPLDFEALNKYVLTVLATDEGEPGLSTVSQLSIQVRNQSNPIFQTL 2162 HSP 13 Score: 54.6842 bits (130), Expect = 6.820e-7 Identity = 112/519 (21.58%), Postives = 200/519 (38.54%), Query Frame = 3
Query: 588 THVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLK-STIILQVDVLDQNEYPALFTRSNYSLSI-IENKDNFSILSFAVIDQDALSFNEFHLNSSNN---FNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDIND-------------------------------------------NVPQYVGRM--SFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNED-LFWISELKI-LQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIE---AGKYDLFLQVTDNG--NPMRNSSANLTIII 1973
TH+V+ I D N++ P + S Y + EN P V + D D+GKNG V I + L F +D + + + +D E + + + D+G P + S + + + + N+ +F R ++++ ++ + + D D L ++ + S N F ME+F SG + + P+ ++ + F + V D + + V V V D D + P++V + S ++ EN+ + + Q D D G N ++ + +L+ SGNED F I L++ S+D E ++I +D G P+ + VNILD NDN P + P + V N G+ + +A D D+ S ++ Y L D +D TGE+ +T ++ ++L++Q D P S+ +L II+
Sbjct: 440 THLVVEITDENDNSPLFTQTS--------------YQATLDENTPVGSSVVKVTAWDSDKGKNGFVTYSIAHSDPLP--FTIDP--------FTGVILTSEHLDFELANRLYHLRVWASDSGSPFSQVSECPVTITLNNINDNFPVFERVGCNITVPLDLPVGREVAKLSAFDSDELEQLQYIIESGNELQVFGMETF--------SGALFLKKPIPPQEG-SFTFRVVV----SDGKHRSEASVVRVTVRDKGDKPTLHCLETGIQKQQTDKLIESMKPVLVNKKEESFSDQHITNRHTPKFVKSVPSSIDVVENHPLNSTILQFKAADGDSGFNGQV-VFALS----------SGNEDGCFCIDTFSGELRLVCSLDRESKEFYILNITAYDLGMPQRSVWKLMAVNILDVNDNPPMFDQPRYVIRVPE----NTAVGSVVFTAQAADMDTDMSGKVQYLLLTSTDLFRVDELTGEVIVTGQLDREAVASHNLWIQARDQAKHGPQLFSTISLLIIL 906
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 160.614 bits (405), Expect = 9.309e-40 Identity = 166/595 (27.90%), Postives = 281/595 (47.23%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS-FVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNL-FYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDN--VVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTKD---IEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E+ +G+ ++++ A D + G +I Y +T +++ SG I +++PL D ++ L+V A D + ++ V+I + DVN++ PNI D R +NG FL E +P N +++ I V DKD NG V C I+ K++ F+L K Y QY L +D E NF I D+G+P L T +++V + D+N+ P +FT+ L+++E NK + + + + D+D+ E + L + +F L + +G + DRE R+ F++ A+DN + A V V VLD NDN P++ F + E N+P Y +G + D D GEN+ IS+S L+ NE+ +++ S D E + D+ D G P + + +N++D NDN P IYP S + +V +S I G+ + V A+D+D+ + L Y + + ++ IDP TG I+L + + G + L + ++D G P
Sbjct: 217 YVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPL-DREETAIHKLSVLASDGSSSPAR---ATVIINVTDVNDNPPNI----DLRYIISPING--TVFLS--EKDPINTKIALITVSDKDTDINGKVICFIE-----KDVPFHL-------KAVYDNQYLLETSALLDYEGTKE-YNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPNASF-------FDLDRKTGVLTASRVFDREDQDRFLFTV----TARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSE-NLPKYSTVGVITVTDSDAGENAAISLS-----------ILNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSI---PGSVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDIGLHRLVVNISDLGYP 760 HSP 2 Score: 62.7734 bits (151), Expect = 1.830e-9 Identity = 131/593 (22.09%), Postives = 243/593 (40.98%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVK--CQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPA------LFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTI 1967
K+ I + D ND AP F + + E+ + S A D ++G Y+LI + F V + +G ++ + D ++ + + VE S + +S + + + DVN+++P V + + + I EN+P V + D D G N ++ Q + K LF L+S L + +++ +DRE+ + S+ D ++T+I ++V D N+ P + + N ++ + E KD N I V D+D + F E + FHL ++ + + LD E + Y F I + + + T A V V + D NDN P + + + ENN L L D+D G+N+ I +L N F + + +L + D E + D G P + ++IV +LDENDN P++ + ++ N+ + + + D+D+ + ++ + +++ +DPF+G I +++ D E Y ++ D+G P +S+A +TI
Sbjct: 126 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSST---AILQVTVTDVNDNKP---VFRENQIE-----------VHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGL--------ITVQRPLDREETAI-HKLSVLASDGSSSPARATVI--INVTDVNDNPPNIDLRYIISPINGTVFLSE-KDPINTKIALITVSDKDTDINGKVICFIEKDV---------PFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQT--ALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEI------------VYQLGPNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTH----NHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSILNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTI 662 HSP 3 Score: 61.6178 bits (148), Expect = 4.104e-9 Identity = 68/292 (23.29%), Postives = 126/292 (43.15%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDI---DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YP-ALFTRSNYSLSII 1055
DYE ++ +++A D G+P L + + + + D ND P F V E+ + + A D +SG +I+Y+L N SF +D +G + + +FD D+ TV A D+ + V++ ++D N++ P + + + +F+ EN P+ V I V D D G+N + I L+ + + ++ S DRE+ S+ F + D+G+P S + ++V+D N+ P ++ SN S ++
Sbjct: 427 DYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPN----ASFFDLDRKTGVLTASR-VFDREDQDRFLFTVTARDNGTPPLQAQ-AAVIVTVLDENDNNP------------KFTHNHFQFFVS--ENLPKYSTVGVITVTDSDAGENAAISLSI-----------LNDNENFILDPFSGVIKSNVSFDREQQSS-YTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLV 686
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 160.229 bits (404), Expect = 1.569e-39 Identity = 166/595 (27.90%), Postives = 281/595 (47.23%), Query Frame = 3
Query: 216 FVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTS-FVSIDGNSGTIILKKPLFDIDKLT---LTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNL-FYLDSRMRLNKNTY--QYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIE-NKDNFSILSFAVIDQDALSFNE--FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDN--TKFTSFATVSVVVLDINDNVPQYV-GRMSFEMKENNIPSYE-LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDN--VVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDS--ISIDPFTGEISLTK---DIEAGKYDLFLQVTDNGNP 1937
+V+++ D G PQ S+ L + + D+ND P F + E+ +G+ ++++ A D + G +I Y +T +++ SG I +++PL D ++ L+V A D + ++ V+I + DVN++ PNI D R +NG FL E +P N +++ I V DKD NG V C I+ K++ F+L K Y QY L +D E NF I D+G+P L T +++V + D+N+ P +FT+ L+++E NK + + + + D+D+ E + L + +F L + +G + DRE R+ F++ A+DN + A V V VLD NDN P++ F + E N+P Y +G + D D GEN+ IS+S L+ NE+ +++ S D E + D+ D G P + + +N++D NDN P IYP S + +V +S I G+ + V A+D+D+ + L Y + + ++ IDP TG I+L + + G + L + ++D G P
Sbjct: 217 YVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPL-DREETAIHKLSVLASDGSSSPAR---ATVIINVTDVNDNPPNI----DLRYIISPING--TVFLS--EKDPINTKIALITVSDKDTDINGKVICFIE-----KDVPFHL-------KAVYDNQYLLETSALLDYEGTKE-YNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPNASF-------FDLDRKTGVLTASRVFDREDQDRFLFTV----TARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSE-NLPKYSTVGVITVTDSDAGENAAISLS-----------ILNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSI---PGSVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDIGLHRLVVNISDLGYP 760 HSP 2 Score: 63.1586 bits (152), Expect = 1.184e-9 Identity = 131/593 (22.09%), Postives = 243/593 (40.98%), Query Frame = 3
Query: 273 KLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED-FSTSFV-SIDGNSGTIILKKPLFDIDK-----LTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC--QIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPA------LFTRSNYSLSIIENKD--NFSILSFAVIDQDA------LSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGR-MSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWIS-ELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEI--SLTKDIE-AGKYDLFLQVTDNGNPMRNSSANLTI 1967
K+ I + D ND AP F + + E+ + S A D ++G Y+LI + F V + +G ++ + D ++ + + VE S + +S + + + DVN+++P V + + + I EN+P V + D D G N ++ Q + K LF L+S L + +++ +DRE+ + S+ D ++T+I ++V D N+ P + + N ++ + E KD N I V D+D + F E + FHL ++ + + LD E + Y F I + + + T A V V + D NDN P + + + ENN L L D+D G+N+ I +L N F + + +L + D E + D G P + ++IV +LDENDN P++ + ++ N+ + + + D+D+ + ++ + +++ +DPF+G I +++ D E Y ++ D+G P +S+A +TI
Sbjct: 126 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSST---AILQVTVTDVNDNKP---VFRENQIE-----------VHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGL--------ITVQRPLDREETAI-HKLSVLASDGSSSPARATVI--INVTDVNDNPPNIDLRYIISPINGTVFLSE-KDPINTKIALITVSDKDTDINGKVICFIEKDV---------PFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQT--ALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEI------------VYQLGPNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTH----NHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSILNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTI 662 HSP 3 Score: 62.3882 bits (150), Expect = 2.563e-9 Identity = 68/292 (23.29%), Postives = 125/292 (42.81%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDI---DKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNE-YP-ALFTRSNYSLSII 1055
DYE ++ +++A D G+P L + + + + D ND P F V E+ + + A D +SG +I+Y+L N SF +D +G + + +FD D+ TV A D+ + V++ ++D N++ P + N + + + EN P+ V I V D D G+N + I L+ + + ++ S DRE+ S+ F + D+G+P S + ++V+D N+ P ++ SN S ++
Sbjct: 427 DYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPN----ASFFDLDRKTGVLTASR-VFDREDQDRFLFTVTARDNGTPPLQAQ-AAVIVTVLDENDNNPKFT-----------HNHFQFF---VSENLPKYSTVGVITVTDSDAGENAAISLSI-----------LNDNENFILDPFSGVIKSNVSFDREQQSS-YTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLV 686
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000043597.1 (SMESG000043597.1) HSP 1 Score: 1467.98 bits (3799), Expect = 0.000e+0 Identity = 760/767 (99.09%), Postives = 765/767 (99.74%), Query Frame = 3
Query: 66 IRIDSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQSINSITRAVLTXXXXXXXXXXXXXXXXXXXVLFLKRRHRSNTDFQFSKSSVVKKNQNFSTSPYRSAQRTSPNQYRNVSPELLMTSLQNPYYFETDLESELPNESEHISNNIAQLFLKVNETLAI 2366
I +DSAQNGVYHYLLECSQKSHRNYFILNRTLSLLSLVLIKSLDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHA+DRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC+IQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGT+LTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQSINSITRAVLTIIFIPSFIIIFSSGFFIFIVLFLKRRHRSNTDFQFSKSSVVKKN+NFSTSPYRSAQRTSPN YRNVSPELLMTSLQNPYYFETDLESELPNESEHISNNIAQLFLKVNETLAI
Sbjct: 159 IDLDSAQNGVYHYLLECSQKSHRNYFILNRTLSLLSLVLIKSLDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAVDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCKIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTRLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQSINSITRAVLTIIFIPSFIIIFSSGFFIFIVLFLKRRHRSNTDFQFSKSSVVKKNRNFSTSPYRSAQRTSPNHYRNVSPELLMTSLQNPYYFETDLESELPNESEHISNNIAQLFLKVNETLAI 925 HSP 2 Score: 57.7658 bits (138), Expect = 3.616e-8 Identity = 38/84 (45.24%), Postives = 50/84 (59.52%), Query Frame = 1
Query: 1 ILDINDNSPKFQKLERHFKILESESI--VLKMEFIIIY*NVHRSLIGIILSSIAPCHCCRWFLS---SLLIMNLFRSLSYN*LP 237
ILDINDNSPKFQKLERHFKILESES+ +K++ I + + +L H + L+ SLL + L +SL Y +P
Sbjct: 124 ILDINDNSPKFQKLERHFKILESESVNFQIKLDQAIDLDSAQNGVYHYLLECSQKSHRNYFILNRTLSLLSLVLIKSLDYEFIP 207
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000043597.1 (SMESG000043597.1) HSP 1 Score: 1454.5 bits (3764), Expect = 0.000e+0 Identity = 753/760 (99.08%), Postives = 758/760 (99.74%), Query Frame = 3
Query: 66 IRIDSAQNGVYHYLLECSQKSHRNYFIXXXXXXXXXXXXXXXXDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQSINSITRAVLTXXXXXXXXXXXXXXXXXXXVLFLKRRHRSNTDFQFSKSSVVKKNQNFSTSPYRSAQRTSPNQYRNVSPELLMTSLQNPYYFETDLESELPNESEHISNNIAQLFLK 2345
I +DSAQNGVYHYLLECSQKSHRNYFILNRTLSLLSLVLIKSLDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHA+DRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKC+IQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGT+LTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQSINSITRAVLTIIFIPSFIIIFSSGFFIFIVLFLKRRHRSNTDFQFSKSSVVKKN+NFSTSPYRSAQRTSPN YRNVSPELLMTSLQNPYYFETDLESELPNESEHISNNIAQLFLK
Sbjct: 159 IDLDSAQNGVYHYLLECSQKSHRNYFILNRTLSLLSLVLIKSLDYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAVDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCKIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTRLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIYQQNMFQSINSITRAVLTIIFIPSFIIIFSSGFFIFIVLFLKRRHRSNTDFQFSKSSVVKKNRNFSTSPYRSAQRTSPNHYRNVSPELLMTSLQNPYYFETDLESELPNESEHISNNIAQLFLK 918 HSP 2 Score: 284.263 bits (726), Expect = 8.509e-81 Identity = 138/145 (95.17%), Postives = 140/145 (96.55%), Query Frame = 1
Query: 2368 NHVKHL*RVKSMKPDCEVCSSADSGQGASEEEILLYNYKSMKPEKLPSQQLSNYIFPPLMEEDGNSYFYANSNKANKLPDGSESEICNCYNQFVNQYAESECAVNILALLQCPVHNQLLPLINSQTNINDDNLITSAIITSDIIR 2802
N++ L KSMKPDCEVCSSADSGQGASEEEILLYNYKSMKPEKLPSQQLSNYIFPPLMEEDGNSYFYANSNKANKLPDGSESEICNCYNQFVNQYAESECAVNILALLQCPVHNQLLPLINSQTNINDDNLITSAIITSDIIR
Sbjct: 910 NNIAQLFLKKSMKPDCEVCSSADSGQGASEEEILLYNYKSMKPEKLPSQQLSNYIFPPLMEEDGNSYFYANSNKANKLPDGSESEICNCYNQFVNQYAESECAVNILALLQCPVHNQLLPLINSQTNINDDNLITSAIITSDIIR 1054 HSP 3 Score: 57.7658 bits (138), Expect = 4.309e-8 Identity = 38/84 (45.24%), Postives = 50/84 (59.52%), Query Frame = 1
Query: 1 ILDINDNSPKFQKLERHFKILESESI--VLKMEFIIIY*NVHRSLIGIILSSIAPCHCCRWFLS---SLLIMNLFRSLSYN*LP 237
ILDINDNSPKFQKLERHFKILESES+ +K++ I + + +L H + L+ SLL + L +SL Y +P
Sbjct: 124 ILDINDNSPKFQKLERHFKILESESVNFQIKLDQAIDLDSAQNGVYHYLLECSQKSHRNYFILNRTLSLLSLVLIKSLDYEFIP 207
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000030992.1 (SMESG000030992.1) HSP 1 Score: 388.267 bits (996), Expect = 4.812e-118 Identity = 226/595 (37.98%), Postives = 362/595 (60.84%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPT-EKLSGNEDLFWISELKILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTKDIEAGKYDLFLQVTDNGNPMRNSSANLTIIIY 1976
D+E + + L L CD G LCS QKL+I+IIDIND APKF+ KNY+ VV E L VGS+ILKVHA D E GDFGKI+Y+L + ++ + F+ ID +G I L KPL ++K+ +T+EA D KF WT ++I IIDVN++RP + + +++ ++ Y ++IFEN P + ++ + V DKD G NG V CQ+ +TK LK+ L + ++ ++ + YKL S D+E ++ ++ +NC DNG P L + + + +++LD NEYP F YS + E + +++ FA+ D DA S NEF +N ++ F + + + +G++ + +P+DREK+ R I ++N DN FTS ++V + V+DINDN P+ VGR +FE+ EN++ LG++ D D N++ SISS+ + C+ + +K++ + + I E++ V +DYE C I + D+G P + +++ + ILDENDN P+W++PSS DN +N+S S +KLTR+RAID D ++ +TY+L ++ +D FTG+++ ++ G Y L + D G P + + +NLTI I+
Sbjct: 217 DFEKVELYNLVLEVCDTGS--LCSKQKLIIEIIDINDMAPKFIQKNYSVVVNETLKVGSLILKVHAYDNEKGDFGKILYRLGDSNEYGSRFIRIDSKTGEIYLIKPLLGLEKILVTIEAQDCGSV-PKFAWTKLLIHIIDVNDNRPEVRFNPSQNVTSKYISDN-FYQIDIFENQPLSIILAIVRVEDKDRGANGKVSCQLHSTKPLKSKEILLNPIK-GRHKF-YKLVTNVSYDKENDNHVSSYFLNCTDNGSPRLSTVVSININILDCNEYPPYFDSQFYSATTTEELKSENVIKFALADADATSTNEFQINGTHG---GWFKIHIIDKKNGKLMLMHPIDREKTDRIDLLIIIINIGLDNKNFTSSSSVLITVIDINDNPPELVGRNNFEVVENSLIESSLGRIKIRDIDQNRNAQFSISSVKSFCFNKSDDKIAIDFQVNKIGEIRSTVV---LDYEKFQQCIISVIATDQGIPSLTSTLTVHLQILDENDNYPQWVFPSSKDNYLNLSVSVTGSSSKLTRIRAIDLDKGANENITYKLHSQLGLFDLDRFTGDLTSISQLKPGNYVLQVSAQDQGLPSKTNYSNLTINIH 799
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000042292.1 (SMESG000042292.1) HSP 1 Score: 244.202 bits (622), Expect = 7.503e-67 Identity = 194/603 (32.17%), Postives = 304/603 (50.41%), Query Frame = 3
Query: 195 DYEFIPKFVLQLIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNEDFSTSFVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQT--TKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVSNPLNFSIN--CQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKD-NFSILSFAVIDQDALSFNEFHLN--SSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQY-VGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEISLTK-DIEAGKYDLFLQVTDNGNPMRNSSANLTIII 1973
DYE + + LIACD G+P LC +Q ++I+I + NDE+P F NYT ++ ED +G ++L A D++ G FG++ Y D + SID +G I + K K +++A D A N T + + ++DVNNH P I V + + +E+ ENN F+++FI V D D+G+N C IQ+ K N F + + + N+ + YKL +S D E+ FS+N C D+G+P + +++ + D+NEY F ++ Y + I EN ++ + V D+D L S F+++ SG I LD EK + F++ +N + FTS A VSV V+D+NDN P++ + FE++EN YE+G++ D+D NS+++ L TT S NE LF ++ I+ ++DYE I + D G P N ++++D NDN P W YP+ DNV+NIS NI+ LTRVRA+D DS N + Y L +D I+ TGEI+ + +I+ G+ L LQ D + ++S +L + I
Sbjct: 209 DYENKKHYQVVLIACDNGKPSLCGNQTVIINITNENDESPMFYRSNYTAIINEDTQIGEIVLSPKAFDKDDGKFGELEYSFSSGADEVKKYFSIDKKTGQISIIKRFNQPTKFKFSIKATDKAP-NPLIGRTWIFLHVVDVNNHSPVILVNPIDSFLISKFQNHTV--IEVSENNRIPFQLAFITVSDLDQGENSRCSCHIQSIINKDHLNYFKIINVIETNERSI-YKLLADKSFDAEETK---YFSLNILCYDHGEPQNSAITKIEIHIKDENEYQPTFDQNLYEIYIKENTSPETNVKTVKVYDRDLTQSRILDLTDPGSTWFSID---------DSGTISTKIVLDYEKIKKLSFNVLAINRGIKS--FTSSARVSVYVIDVNDNFPKFSLASKRFEVEENLKGFYEIGKIHAFDEDSEINSKLNYYLLNTT--SENNARSINEKLFELNPTTGIIYSNVTLDYEECDLYSITVKVIDSGRPPLSNIQRFFIHVVDMNDNGPIWKYPNIHDNVMNISLQNIRDSV-LTRVRAVDNDSDKYNVVHYFLHNHNDIFEINHLTGEITFKRLNIKPGQLTLQLQAIDANSKNIHTSQSLIVYI 790
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000045211.1 (SMESG000045211.1) HSP 1 Score: 236.113 bits (601), Expect = 9.953e-66 Identity = 183/566 (32.33%), Postives = 284/566 (50.18%), Query Frame = 3
Query: 228 LIACDIGQPQLCSSQKLVIDIIDINDEAPKFVAKNYTKVVQEDLAVGSVILKVHAIDRESGDFGKIIYKLIKNED--FSTSFVSIDGNSGTIILKKPLFDID---KLTLTVEAHDSAEHNSKFDWTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYFLE-----IFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLN-----KNTYQYKLRIRQSIDREKVSNPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIEN--KDNFSILSFAVIDQDALSFNEFHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSFATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYELGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNEDLFWISELK-ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYELKAKHDSISIDPFTGEIS 1871
L CD G +LC++Q L I I+D ND PK V +Y + ED G++IL V A D + G FG + Y + N + F + SID G I L K L D+ ++ L VE D ++S V I IID NNHRP+I + +P+Y L+ + EN P + + V D D +NG+V C++ ++N D R+ LN KNT Y L+ +Q DRE + + C DNG P L S I L + + D NE+ FT +N ++S+ EN +D F IL IDQDA S +F L+ S + F+++S +SG I DRE +YQF +FV++ +FT +SV++ D NDN P SF++KEN P +G L+ D D+ EN + +T T +K++ N F+I ++K + ++ +D E K+ I D G P ++ V I+D NDN P+W + +S +++I+ + S T + ++ +D D + SN +Y L+ + ++ TG++S
Sbjct: 215 LEVCDNGPKRLCANQFLNIKILDYNDNKPKCVESHYKVRIAEDTEPGTIILTVSATDDDQGAFGNLSYVFLMNRNLKFINKYFSIDKYRGEISLLKQL-DVKMSTQIDLIVEVRDGYGYDSHMVQCSVTINIIDKNNHRPDIKI-------------HPVYLLKNNKLTLMENEPIGTTICMLIVTDNDLDENGEVTCKLT----MQN----DERVALNFATNLKNTRIYSLKSKQIFDRETMEG-FAIQVRCTDNGLPSLTSDINLDILLTDDNEFSPKFTNANLTVSLSENSPRDLF-ILQVKAIDQDADSVLKFQLSRSVR---DLFYVNS---TSGAIYTKKSFDRETKEKYQFEVFVIDHGVKQ-QFTGVCLISVIITDQNDNAPSLTNPKSFKIKENEKPYSIVGTLMSIDPDLKENGTVHFQLITIT--SRYQKINNNT--FFIDQVKGTIFTQKKLDREAFFEYKLHILLKDNGTPTLSRIETVTVEIVDVNDNAPKWAFQNSFQKLISITQAQLLSSTDIFTLKVVDED-LDSN-CSYFLEVPNKYFLLNHITGQVS 743 HSP 2 Score: 61.6178 bits (148), Expect = 2.504e-9 Identity = 128/546 (23.44%), Postives = 234/546 (42.86%), Query Frame = 3
Query: 465 FVSIDGNSGTIILKKPLFDIDKLTLTVEAHDSAEHNSKFD-------WTHVVIFIIDVNNHRPNISVGSDKRTSTQLLNGYPIYF--LEIFENNPENFEVSFINVVDKDEGKNGDVKCQIQTTKLLKNLFYLDSRMRLNKNTYQYKLRIRQSIDREKVS-NPLNFSINCQDNGQPLLKSTIILQVDVLDQNEYPALFTRSNYSLSIIENKDNFS-ILSFAVIDQDALSFNE----FHLNSSNNFNMESFHLSSLTQSSGEIRIGNPLDREKSPRYQFSIFVVNEAQDNTKFTSF---ATVSVVVLDINDNVPQYVGRMSFEMKENNIPSYE-------LGQLIFDDKDIGENSRISISSLTTTCYGPTEKLSGNED----LFWISELK-----ILQVKQSMDYEFIHNCKIDIHFHDEGFPKNHNKISIIVNILDENDNEPEWIYPSSLDNVVNISHINIQSGTKLTRVRAIDADSVSSNRLTYEL-KAKHDSISIDPFTGEISLTKDIE---AGKYDLFLQVTDNGNPMRNSSANL-TIIIYQQN 1985
+++D SG + ++KP ID+ T+ E+ +F W +V IFI DVN++ P +P F +EI EN P ++V ++V ++ ++ ++ KLL + L+ L + +D EK N ++ DNG L + L + +LD N+ S+Y + I E+ + + IL+ + D D +F F +N + F + F S+ + GEI + LD + S + I ++ E +D + S +V++ ++D N++ P + +K N + E + LI D D+ EN + TC KL+ D L + + LK L+ KQ D E + I + D G P + I++ + + D+N+ P++ ++ + V++S N + +V+AID D+ S L ++L ++ D ++ +G I K + KY + V D+G + + L ++II QN
Sbjct: 76 LINLDKQSGKLTIRKP---IDRETVCPESEKGHLCKLEFTVLVPKDTWINVEIFIQDVNDNPPT----------------FPSKFKYIEISENVPIGYKV-LLDVPKDNDAQDSVLENYNLYGKLL-------THFSLSILPKPLSLVVISKLDHEKEDYRHFNGTLEVCDNGPKRLCANQFLNIKILDYNDNKPKCVESHYKVRIAEDTEPGTIILTVSATDDDQGAFGNLSYVFLMNRNLKFINKYF---SIDKYRGEISLLKQLDVKMSTQ----IDLIVEVRDGYGYDSHMVQCSVTINIIDKNNHRPDIKIHPVYLLKNNKLTLMENEPIGTTICMLIVTDNDLDENGEV-------TC-----KLTMQNDERVALNFATNLKNTRIYSLKSKQIFDRETMEGFAIQVRCTDNGLPSLTSDINLDILLTDDNEFSPKF---TNANLTVSLSE-NSPRDLFILQVKAIDQDADSV--LKFQLSRSVRDLFYVNSTSGAIYTKKSFDRETKEKYQFEVFVIDHGVKQQFTGVCLISVIITDQN 569 The following BLAST results are available for this feature:
BLAST of Protocadherin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30015050 ID=SMED30015050|Name=Protocadherin|organism=Schmidtea mediterranea sexual|type=transcript|length=2871bpback to top protein sequence of SMED30015050-orf-1 >SMED30015050-orf-1 ID=SMED30015050-orf-1|Name=SMED30015050-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=135bp MKPDCEVCSSADSGQGASEEEILLYNYKSMKPEKLPSQQLSNYIFPPLMEback to top protein sequence of SMED30015050-orf-2 >SMED30015050-orf-2 ID=SMED30015050-orf-2|Name=SMED30015050-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=789bp FRHQRQQSKVSEAGKAFQNPRIRIDSAQNGVYHYLLECSQKSHRNYFILNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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