Calcium/calmodulin-dependent protein kinase type II subunit delta

Overview
NameCalcium/calmodulin-dependent protein kinase type II subunit delta
Smed IDSMED30015021
Length (bp)4551
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Calcium/calmodulin-dependent protein kinase type II subunit delta (SMED30015021) t-SNE clustered cells

Violin plots show distribution of expression levels for Calcium/calmodulin-dependent protein kinase type II subunit delta (SMED30015021) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calcium/calmodulin-dependent protein kinase type II subunit delta (SMED30015021) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Calcium/calmodulin-dependent protein kinase type II subunit delta (SMED30015021) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30015021

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymal cellSMED30015021SMESG000019086.1 SMESG000006795.1 SMESG000044348.1 SMESG000042307.1 dd_Smed_v4_1035_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30015021SMESG000062800.1 dd_Smed_v4_7858_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30015021SMESG000062800.1 dd_Smed_v4_7858_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
headSMED30015021SMESG000062800.1 dd_Smed_v6_7858_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
parenchymal cellSMED30015021SMESG000019086.1 SMESG000006795.1 SMESG000044348.1 SMESG000042307.1 dd_Smed_v6_1035_1dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30015021SMESG000019086.1 SMESG000006795.1 SMESG000044348.1 SMESG000042307.1 dd_Smed_v4_1035_1_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Human
Match: CBLB (Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:1542])

HSP 1 Score: 198.364 bits (503), Expect = 1.109e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Human
Match: CBLB (Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:1542])

HSP 1 Score: 197.978 bits (502), Expect = 2.082e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Human
Match: CBLB (Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:1542])

HSP 1 Score: 198.364 bits (503), Expect = 3.358e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   60 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 444          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Human
Match: CBLB (Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:1542])

HSP 1 Score: 197.978 bits (502), Expect = 3.893e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Human
Match: CBLB (Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:1542])

HSP 1 Score: 197.978 bits (502), Expect = 4.001e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Celegans
Match: sli-1 (Suppressor of LIneage defect [Source:UniProtKB/TrEMBL;Acc:Q95ZR5])

HSP 1 Score: 164.081 bits (414), Expect = 2.405e-42
Identity = 109/377 (28.91%), Postives = 186/377 (49.34%), Query Frame = 2
Query:  104 CDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDY-PFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVIY-SHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRK--EIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYD--KRNCPFCNQKIQSTTKIV 1213
            C    ++++ C+   L + +    P    +     + L LI + +     D L +  Y+     +MIN      K  + +   I       R+      + F  + FEI+A FP GIY     +++K  A  +W   F     V    F +  ++ +   I + E    K +I+ +  +F + FEFD+FTRL+ P++ +++ W+ +  +HP Y  F TY + K  L +   +PG+Y+FR+SC   G W IGYV    ++ Q      +LI+AL EG+K   Y+YPNG   + +LS L +  +   + V +E  +LY E    F+ CKIC ++EK++++E CGH +C  C    +  D     CPFC  +I+ T +++
Sbjct:   56 CKFMDQVVKSCHSPRLNLKN--SPPFILDILPDTYTHLMLIFTQNN----DILQDNDYLKIFLESMINKCKEIIKLFKTSA--IYNDQSEERRKLTKMSLTFSHMLFEIKALFPEGIYIEDRFRMTKKEAESFWSHHFTKKNIVPWSTFFTALEKHHGSTIGKMEAAELKATIDLSGDDFISNFEFDVFTRLFYPFKTLIKNWQTLTTAHPGYCAFLTYDEVKKRLEKLTKKPGSYIFRLSCTRPGQWAIGYVAPDGKIYQTIPQNKSLIQALHEGHKEGFYIYPNGRDQDINLSKLMDVPQADRVQVTSEQYELYCEMGTTFELCKICDDNEKNIKIEPCGHLLCAKCLANWQDSDGGGNTCPFCRYEIKGTNRVI 424          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Celegans
Match: sli-1 (Suppressor of LIneage defect [Source:UniProtKB/TrEMBL;Acc:Q95ZR5])

HSP 1 Score: 164.081 bits (414), Expect = 4.428e-42
Identity = 109/377 (28.91%), Postives = 186/377 (49.34%), Query Frame = 2
Query:  104 CDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDY-PFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVIY-SHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRK--EIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYD--KRNCPFCNQKIQSTTKIV 1213
            C    ++++ C+   L + +    P    +     + L LI + +     D L +  Y+     +MIN      K  + +   I       R+      + F  + FEI+A FP GIY     +++K  A  +W   F     V    F +  ++ +   I + E    K +I+ +  +F + FEFD+FTRL+ P++ +++ W+ +  +HP Y  F TY + K  L +   +PG+Y+FR+SC   G W IGYV    ++ Q      +LI+AL EG+K   Y+YPNG   + +LS L +  +   + V +E  +LY E    F+ CKIC ++EK++++E CGH +C  C    +  D     CPFC  +I+ T +++
Sbjct:   56 CKFMDQVVKSCHSPRLNLKN--SPPFILDILPDTYTHLMLIFTQNN----DILQDNDYLKIFLESMINKCKEIIKLFKTSA--IYNDQSEERRKLTKMSLTFSHMLFEIKALFPEGIYIEDRFRMTKKEAESFWSHHFTKKNIVPWSTFFTALEKHHGSTIGKMEAAELKATIDLSGDDFISNFEFDVFTRLFYPFKTLIKNWQTLTTAHPGYCAFLTYDEVKKRLEKLTKKPGSYIFRLSCTRPGQWAIGYVAPDGKIYQTIPQNKSLIQALHEGHKEGFYIYPNGRDQDINLSKLMDVPQADRVQVTSEQYELYCEMGTTFELCKICDDNEKNIKIEPCGHLLCAKCLANWQDSDGGGNTCPFCRYEIKGTNRVI 424          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Celegans
Match: sli-1 (Suppressor of LIneage defect [Source:UniProtKB/TrEMBL;Acc:Q95ZR5])

HSP 1 Score: 164.081 bits (414), Expect = 5.801e-42
Identity = 109/377 (28.91%), Postives = 186/377 (49.34%), Query Frame = 2
Query:  104 CDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDY-PFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVIY-SHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRK--EIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYD--KRNCPFCNQKIQSTTKIV 1213
            C    ++++ C+   L + +    P    +     + L LI + +     D L +  Y+     +MIN      K  + +   I       R+      + F  + FEI+A FP GIY     +++K  A  +W   F     V    F +  ++ +   I + E    K +I+ +  +F + FEFD+FTRL+ P++ +++ W+ +  +HP Y  F TY + K  L +   +PG+Y+FR+SC   G W IGYV    ++ Q      +LI+AL EG+K   Y+YPNG   + +LS L +  +   + V +E  +LY E    F+ CKIC ++EK++++E CGH +C  C    +  D     CPFC  +I+ T +++
Sbjct:   73 CKFMDQVVKSCHSPRLNLKN--SPPFILDILPDTYTHLMLIFTQNN----DILQDNDYLKIFLESMINKCKEIIKLFKTSA--IYNDQSEERRKLTKMSLTFSHMLFEIKALFPEGIYIEDRFRMTKKEAESFWSHHFTKKNIVPWSTFFTALEKHHGSTIGKMEAAELKATIDLSGDDFISNFEFDVFTRLFYPFKTLIKNWQTLTTAHPGYCAFLTYDEVKKRLEKLTKKPGSYIFRLSCTRPGQWAIGYVAPDGKIYQTIPQNKSLIQALHEGHKEGFYIYPNGRDQDINLSKLMDVPQADRVQVTSEQYELYCEMGTTFELCKICDDNEKNIKIEPCGHLLCAKCLANWQDSDGGGNTCPFCRYEIKGTNRVI 441          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305])

HSP 1 Score: 127.872 bits (320), Expect = 2.836e-32
Identity = 54/144 (37.50%), Postives = 94/144 (65.28%), Query Frame = 3
Query: 3837 KSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKS 4268
            K   E    I  N   K +KQ+I+++T+ LL +I+  ++ ++ +L D  +T FEP+  GNLIEGI++++F F+     +    V+ ++LNP +HI+GED A +A+VK+ Q +D+NG     + +E+R+W +K+G+W  +HVH+S
Sbjct:  118 KESSESSQTIDDNDSEKAQKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFDGNRKNQ----VHTTMLNPNVHIIGEDAACVAYVKLTQFLDRNGEAHTRQSQESRVWSKKQGRWVCVHVHRS 257          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305])

HSP 1 Score: 124.79 bits (312), Expect = 8.672e-32
Identity = 49/126 (38.89%), Postives = 88/126 (69.84%), Query Frame = 3
Query: 3891 KKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKS 4268
            +KQ+I+++T+ LL +I+  ++ ++ +L D  +T FEP+  GNLIEGI++++F F+          V+ ++LNP +HI+GED A +A+VK+ Q +D+NG     + +E+R+W +K+G+W  +HVH+S
Sbjct:   82 QKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFDG----NRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDRNGEAHTRQSQESRVWSKKQGRWVCVHVHRS 203          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Fly
Match: Cbl (gene:FBgn0020224 transcript:FBtr0076614)

HSP 1 Score: 203.371 bits (516), Expect = 3.140e-56
Identity = 122/391 (31.20%), Postives = 211/391 (53.96%), Query Frame = 2
Query:   80 EKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLR-KYDKRNCPFCNQKIQSTTKI-VNVKDPSK 1234
            +KK +E       K++++C +  + + +    P    +      +L LI S +  + +  L+   +     NN++       K  ++    +  ++ H R+      + F  +  E++A FPNG+++    +I+K  A  +W+  FG++  V   +F  +  + +P I+  E  + K +I+ T  +F + FEFD+FTRL+ PW  +L  W+++  +HP Y+ F TY + K  L RY+ + G+YVFR+SC  LG W IGYV +  E+ Q      +L +AL++G++   YLYP+G++ NPDLS+  +   E  I V  E  +LY E    F+ CKIC E++KD+++E CGH +C  C    +   + + CPFC  +I+ T +I V+  DP K
Sbjct:   40 DKKTLEKTWKLMDKVVKLCQQPKMNLKNSP--PFILDILPDTYQRLRLIYSKNEDQ-MHLLHANEHFNVFINNLMRKCKQAIKLFKEGKEKMFDENSHYRRNLTKLSLVFSHMLSELKAIFPNGVFAGDQFRITKADAADFWKSNFGNSTLVPWKIFRQELNKVHPIISGLEAMALKTTIDLTCNDFISNFEFDVFTRLFQPWVTLLRNWQILAVTHPGYVAFLTYDEVKARLQRYILKAGSYVFRLSCTRLGQWAIGYVTAEGEILQTIPQNKSLCQALLDGHREGFYLYPDGQAYNPDLSSAVQSPTEDHITVTQEQYELYCEMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEIKGTEQIVVDAFDPRK 427          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Fly
Match: Cbl (gene:FBgn0020224 transcript:FBtr0076615)

HSP 1 Score: 201.83 bits (512), Expect = 1.076e-52
Identity = 108/297 (36.36%), Postives = 175/297 (58.92%), Query Frame = 2
Query:  362 KDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLR-KYDKRNCPFCNQKIQSTTKI-VNVKDPSK 1234
            ++ H R+      + F  +  E++A FPNG+++    +I+K  A  +W+  FG++  V   +F  +  + +P I+  E  + K +I+ T  +F + FEFD+FTRL+ PW  +L  W+++  +HP Y+ F TY + K  L RY+ + G+YVFR+SC  LG W IGYV +  E+ Q      +L +AL++G++   YLYP+G++ NPDLS+  +   E  I V  E  +LY E    F+ CKIC E++KD+++E CGH +C  C    +   + + CPFC  +I+ T +I V+  DP K
Sbjct:  131 ENSHYRRNLTKLSLVFSHMLSELKAIFPNGVFAGDQFRITKADAADFWKSNFGNSTLVPWKIFRQELNKVHPIISGLEAMALKTTIDLTCNDFISNFEFDVFTRLFQPWVTLLRNWQILAVTHPGYVAFLTYDEVKARLQRYILKAGSYVFRLSCTRLGQWAIGYVTAEGEILQTIPQNKSLCQALLDGHREGFYLYPDGQAYNPDLSSAVQSPTEDHITVTQEQYELYCEMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTSWQVDSEGQGCPFCRAEIKGTEQIVVDAFDPRK 427          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0300378)

HSP 1 Score: 152.14 bits (383), Expect = 3.058e-38
Identity = 62/137 (45.26%), Postives = 99/137 (72.26%), Query Frame = 3
Query: 3870 ANADCKN-KKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNA 4277
             N+ C + ++QEI+K+TE L+ +I +G++  + K+ DP +T FEP+  GNL+EGID++KF F NV  K + K++N +ILNP +H+LGE+ A IA+V++ Q +DK G     + EETR+W +++ KWQN+H H+S +A
Sbjct:  381 GNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGK-NCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSASA 516          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0100146)

HSP 1 Score: 152.14 bits (383), Expect = 3.058e-38
Identity = 62/137 (45.26%), Postives = 99/137 (72.26%), Query Frame = 3
Query: 3870 ANADCKN-KKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNA 4277
             N+ C + ++QEI+K+TE L+ +I +G++  + K+ DP +T FEP+  GNL+EGID++KF F NV  K + K++N +ILNP +H+LGE+ A IA+V++ Q +DK G     + EETR+W +++ KWQN+H H+S +A
Sbjct:  381 GNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGK-NCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSASA 516          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0300379)

HSP 1 Score: 152.14 bits (383), Expect = 3.909e-38
Identity = 62/138 (44.93%), Postives = 99/138 (71.74%), Query Frame = 3
Query: 3870 ANADCKN--KKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNA 4277
             N+ C +  ++QEI+K+TE L+ +I +G++  + K+ DP +T FEP+  GNL+EGID++KF F NV  K + K++N +ILNP +H+LGE+ A IA+V++ Q +DK G     + EETR+W +++ KWQN+H H+S +A
Sbjct:  381 GNSQCSSAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGK-NCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAHTHQSEETRVWHKRDNKWQNVHFHRSASA 517          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Zebrafish
Match: cbl (Cbl proto-oncogene, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-041114-207])

HSP 1 Score: 201.83 bits (512), Expect = 1.937e-52
Identity = 122/392 (31.12%), Postives = 202/392 (51.53%), Query Frame = 2
Query:   77 IEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV----NVKDP 1228
            ++KK +E       K++++C    L + +    P+   +       L  ILS    K ++ L +  Y      N+           +D    +  ++   R+      + F  +  E++A FPNG++   N +I+K  A  +W + FGD   V   VF     E +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  +L  W  +  +HP Y+ F TY + K  L +++++PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G +   YL+P+G + NPDL+ L E   +  I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ + + CPFC  +I+ T  IV    + KDP
Sbjct:   35 VDKKTVEKCWKFMDKVVRLCQNPKLALKNSP--PYILDLLPDTYQHLRTILSRYEGK-METLGDNEYFRVFMENLTKKTKQTISLFKDGKERMFEENSQPRRNLTKLSLIFSHMLAELKAIFPNGLFQGDNFRITKADAAEFWRRSFGDKTIVPWKVFRQALHEFHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRTQNPDLTGLCEPSPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESEGQGCPFCRCEIKGTEPIVVDPFDPKDP 423          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Zebrafish
Match: cblb (Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-030616-417])

HSP 1 Score: 192.586 bits (488), Expect = 2.249e-49
Identity = 103/273 (37.73%), Postives = 155/273 (56.78%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  +  EI+A FP G +     +I+K  A  +W + FG+   V   +F     + +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y+N+PG+Y+FR+SC  LG W IGYV S   + Q       L +AL++G +   YL+P+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    +  D + CPFC  +I+ T  I+
Sbjct:  145 FSHMLAEIKAIFPGGQFQGDTFRITKADAAEFWRRSFGEKTIVPWKMFRQCLHDVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYINKPGSYIFRLSCTRLGQWAIGYVTSDGNILQTIPHNKPLFQALIDGCREGFYLFPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQDSDGQGCPFCRCEIKGTEPII 417          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Zebrafish
Match: cblb (Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-030616-417])

HSP 1 Score: 192.2 bits (487), Expect = 2.279e-49
Identity = 103/273 (37.73%), Postives = 155/273 (56.78%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  +  EI+A FP G +     +I+K  A  +W + FG+   V   +F     + +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y+N+PG+Y+FR+SC  LG W IGYV S   + Q       L +AL++G +   YL+P+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    +  D + CPFC  +I+ T  I+
Sbjct:  145 FSHMLAEIKAIFPGGQFQGDTFRITKADAAEFWRRSFGEKTIVPWKMFRQCLHDVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYINKPGSYIFRLSCTRLGQWAIGYVTSDGNILQTIPHNKPLFQALIDGCREGFYLFPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQDSDGQGCPFCRCEIKGTEPII 417          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Zebrafish
Match: cblb (Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-030616-417])

HSP 1 Score: 192.2 bits (487), Expect = 2.563e-49
Identity = 103/273 (37.73%), Postives = 155/273 (56.78%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  +  EI+A FP G +     +I+K  A  +W + FG+   V   +F     + +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y+N+PG+Y+FR+SC  LG W IGYV S   + Q       L +AL++G +   YL+P+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    +  D + CPFC  +I+ T  I+
Sbjct:  145 FSHMLAEIKAIFPGGQFQGDTFRITKADAAEFWRRSFGEKTIVPWKMFRQCLHDVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYINKPGSYIFRLSCTRLGQWAIGYVTSDGNILQTIPHNKPLFQALIDGCREGFYLFPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQDSDGQGCPFCRCEIKGTEPII 417          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Zebrafish
Match: cblc (Cbl proto-oncogene C, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-080220-20])

HSP 1 Score: 184.496 bits (467), Expect = 3.418e-49
Identity = 95/273 (34.80%), Postives = 148/273 (54.21%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  +  E++  FP G +     +++K  A+ +W K FG    V  +VF  + K  + F    E  + K++++ T  +  + FEFD+FTRL+ PW  ++  W  +  +HP Y+ F TY   K  L  Y + PG+Y+FR+SC  +G W IG+V S   + Q     + L +AL++G +   YLYP+G   NPDLS+L     +  + V  E  +LY E    F+ CKIC E +KD +++ CGH +CQ C    +K D   CP+C   I+ T  I+
Sbjct:  140 FSHMLNELRTIFPGGRFQGDTYRVTKTEAKEFWRKTFGHKCIVQWNVFKQQLKRVHYFEEGMEAMALKSTVDLTCNDHISIFEFDIFTRLFQPWSTLIRNWNHLAVTHPGYMAFLTYDQVKARLEHYRHRPGSYIFRLSCTQMGQWAIGHVTSDGSIVQTIPQNTPLYQALIQGFREGCYLYPDGRDVNPDLSSLCSPVHKGRVKVTEEQYELYCEIGSTFQLCKICTERDKDTRIQPCGHLLCQPCLTGWQKSDGHTCPYCRCDIRGTESIL 412          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Xenopus
Match: cblb (Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:NCBI gene;Acc:448509])

HSP 1 Score: 195.282 bits (495), Expect = 8.635e-51
Identity = 120/387 (31.01%), Postives = 199/387 (51.42%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L + +    P+   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FP+G +   N +I+K  A  +W K FG+   V   +F     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  IV
Sbjct:   49 QAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSP--PYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQERRNLTKLSLIFSHMLAEIKAIFPSGQFQGDNFRITKADAAEFWRKFFGERTIVPWKIFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWTSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTDLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESDGQGCPFCRCEIKGTEPIV 433          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Xenopus
Match: cblb (Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:NCBI gene;Acc:448509])

HSP 1 Score: 194.512 bits (493), Expect = 6.787e-50
Identity = 123/388 (31.70%), Postives = 199/388 (51.29%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FP+G +   N +I+K  A  +W K FG+   V   +F     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  IV
Sbjct:   49 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQERRNLTKLSLIFSHMLAEIKAIFPSGQFQGDNFRITKADAAEFWRKFFGERTIVPWKIFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWTSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTDLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESDGQGCPFCRCEIKGTEPIV 433          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Xenopus
Match: cblb (Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:NCBI gene;Acc:448509])

HSP 1 Score: 194.126 bits (492), Expect = 7.021e-50
Identity = 120/387 (31.01%), Postives = 199/387 (51.42%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L + +    P+   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FP+G +   N +I+K  A  +W K FG+   V   +F     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  IV
Sbjct:   49 QAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSP--PYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQERRNLTKLSLIFSHMLAEIKAIFPSGQFQGDNFRITKADAAEFWRKFFGERTIVPWKIFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWTSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTDLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESDGQGCPFCRCEIKGTEPIV 433          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Xenopus
Match: cblb (Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:NCBI gene;Acc:448509])

HSP 1 Score: 194.126 bits (492), Expect = 7.856e-50
Identity = 123/388 (31.70%), Postives = 199/388 (51.29%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FP+G +   N +I+K  A  +W K FG+   V   +F     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  IV
Sbjct:   49 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQERRNLTKLSLIFSHMLAEIKAIFPSGQFQGDNFRITKADAAEFWRKFFGERTIVPWKIFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWTSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTDLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESDGQGCPFCRCEIKGTEPIV 433          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Xenopus
Match: cblb (Cbl proto-oncogene B, E3 ubiquitin protein ligase [Source:NCBI gene;Acc:448509])

HSP 1 Score: 194.126 bits (492), Expect = 9.349e-50
Identity = 123/388 (31.70%), Postives = 199/388 (51.29%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FP+G +   N +I+K  A  +W K FG+   V   +F     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  IV
Sbjct:   49 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQERRNLTKLSLIFSHMLAEIKAIFPSGQFQGDNFRITKADAAEFWRKFFGERTIVPWKIFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWTSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTDLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESDGQGCPFCRCEIKGTEPIV 433          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Mouse
Match: Cblb (Casitas B-lineage lymphoma b [Source:MGI Symbol;Acc:MGI:2146430])

HSP 1 Score: 198.364 bits (503), Expect = 3.483e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Mouse
Match: Cblb (Casitas B-lineage lymphoma b [Source:MGI Symbol;Acc:MGI:2146430])

HSP 1 Score: 198.364 bits (503), Expect = 3.483e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Mouse
Match: Cblb (Casitas B-lineage lymphoma b [Source:MGI Symbol;Acc:MGI:2146430])

HSP 1 Score: 198.364 bits (503), Expect = 4.687e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYS-TVFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Mouse
Match: Cblb (Casitas B-lineage lymphoma b [Source:MGI Symbol;Acc:MGI:2146430])

HSP 1 Score: 198.364 bits (503), Expect = 4.687e-51
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYS-TVFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Mouse
Match: Cblb (Casitas B-lineage lymphoma b [Source:MGI Symbol;Acc:MGI:2146430])

HSP 1 Score: 192.971 bits (489), Expect = 7.909e-50
Identity = 106/270 (39.26%), Postives = 154/270 (57.04%), Query Frame = 2
Query:  416 LYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:    1 MLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 270          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. UniProt/SwissProt
Match: sp|Q8K4S7|CBLB_RAT (E3 ubiquitin-protein ligase CBL-B OS=Rattus norvegicus OX=10116 GN=Cblb PE=1 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 2.547e-50
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. UniProt/SwissProt
Match: sp|Q3TTA7|CBLB_MOUSE (E3 ubiquitin-protein ligase CBL-B OS=Mus musculus OX=10090 GN=Cblb PE=1 SV=3)

HSP 1 Score: 198.364 bits (503), Expect = 3.278e-50
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYS-TVFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. UniProt/SwissProt
Match: sp|Q13191|CBLB_HUMAN (E3 ubiquitin-protein ligase CBL-B OS=Homo sapiens OX=9606 GN=CBLB PE=1 SV=2)

HSP 1 Score: 197.978 bits (502), Expect = 4.230e-50
Identity = 125/388 (32.22%), Postives = 198/388 (51.03%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FPNG +   N +I+K  A  +W K FGD   V   VF     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  I+
Sbjct:   38 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. UniProt/SwissProt
Match: sp|Q9ULV8|CBLC_HUMAN (E3 ubiquitin-protein ligase CBL-C OS=Homo sapiens OX=9606 GN=CBLC PE=1 SV=3)

HSP 1 Score: 187.963 bits (476), Expect = 1.043e-49
Identity = 99/279 (35.48%), Postives = 153/279 (54.84%), Query Frame = 2
Query:  374 MRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLN--EFRKEIVVNNEDLQLYECFDD-FKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQS 1198
            +R+      + F  ++ E+ A FP G Y  H  +++K PA  +W +  G    +    F S     +P        + + +I+ T +   + FEFD+FTRL+ PW  +L+ W+++  +HP Y+ F TY + ++ L    ++PG+Y+FR SC  LG W IGYV S   + Q       L + L+EG K   YLYP+G++ NPDL+ L   E ++ I V+ E LQLY   D  F+ CKIC ES KD+++E CGH +C  C    +  D + CPFC  +I+ 
Sbjct:  117 LRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKG 395          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. UniProt/SwissProt
Match: sp|Q6DFR2|CBLB_XENTR (E3 ubiquitin-protein ligase CBL-B OS=Xenopus tropicalis OX=8364 GN=cblb PE=2 SV=1)

HSP 1 Score: 193.356 bits (490), Expect = 1.006e-48
Identity = 123/388 (31.70%), Postives = 199/388 (51.29%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++  +++ +E       K++++C    L    LK  P Y   +       L LILS  D ++ L  L+   Y     ++++       +  ++    +  +    R+      + F  +  EI+A FP+G +   N +I+K  A  +W K FG+   V   +F     E +   +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y  +PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G++   YLYP+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T  IV
Sbjct:   49 QAAADRRTVEKTWKLMDKVVRLCQNPKL---QLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQERRNLTKLSLIFSHMLAEIKAIFPSGQFQGDNFRITKADAAEFWRKFFGERTIVPWKIFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWTSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTDLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESDGQGCPFCRCEIKGTEPIV 433          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. TrEMBL
Match: A0A2C9KBL2 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106052457 PE=4 SV=1)

HSP 1 Score: 223.016 bits (567), Expect = 1.869e-57
Identity = 131/416 (31.49%), Postives = 218/416 (52.40%), Query Frame = 2
Query:   44 LIPIEMNSESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV------------NVKDPSKDVD 1243
            L+P ++ +   ++KK IE       K++++C    + + +    P    +       L  I S    K +  LN   Y      N++N   +  K  +D    +  ++ H R+      + F  +  E++A +PNG ++  + +I+K  A  WW+K FGD I +    F +   E +P  +  E  + K++I+ T  ++ + FEFD+F RL+ PW  +L  W V+  +HP Y+ F TY + K  L +Y+N+PG+YVFR+SC  LG W IGYV + +++ Q      +L +AL++G +   +LYP+G S NPDLS L    +E  I V  E  +LY E    F++CKIC E++KD++LE CGH +C  C    +  D + CP+C  +I+ T +++              K P++DVD
Sbjct:   22 LVPPKLTA---VDKKTIEKSWKMMDKVVKLCQHPKMSLRNSP--PFILDILPDTYQHLRTICSKHDEK-VQSLNECEYFRTFIENLMNKCKNTIKLFRDGKDKMYDENSHCRRNLTKLSLVFSHMLAELKAIYPNGSFAGESFRITKGDAADWWKKSFGDKIIIPWKEFKNTLHETHPIGSPLEAMALKSTIDLTCNDYISVFEFDVFCRLFQPWANLLRNWNVLAVTHPGYVAFLTYDEVKARLQKYINKPGSYVFRLSCTRLGQWAIGYVTTDRQILQTIPQNKSLCQALLDGQREGFFLYPDGRSVNPDLSNLVADSEEDHIRVTQEQYELYCEMGSTFQQCKICAENDKDIRLEPCGHLLCTPCLTQWQDSDGQGCPWCRCEIKGTEQVIVDPFDERQVLKAGSKTPTQDVD 431          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. TrEMBL
Match: A0A2C9KBE0 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106052457 PE=4 SV=1)

HSP 1 Score: 223.016 bits (567), Expect = 2.432e-57
Identity = 131/416 (31.49%), Postives = 218/416 (52.40%), Query Frame = 2
Query:   44 LIPIEMNSESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV------------NVKDPSKDVD 1243
            L+P ++ +   ++KK IE       K++++C    + + +    P    +       L  I S    K +  LN   Y      N++N   +  K  +D    +  ++ H R+      + F  +  E++A +PNG ++  + +I+K  A  WW+K FGD I +    F +   E +P  +  E  + K++I+ T  ++ + FEFD+F RL+ PW  +L  W V+  +HP Y+ F TY + K  L +Y+N+PG+YVFR+SC  LG W IGYV + +++ Q      +L +AL++G +   +LYP+G S NPDLS L    +E  I V  E  +LY E    F++CKIC E++KD++LE CGH +C  C    +  D + CP+C  +I+ T +++              K P++DVD
Sbjct:   22 LVPPKLTA---VDKKTIEKSWKMMDKVVKLCQHPKMSLRNSP--PFILDILPDTYQHLRTICSKHDEK-VQSLNECEYFRTFIENLMNKCKNTIKLFRDGKDKMYDENSHCRRNLTKLSLVFSHMLAELKAIYPNGSFAGESFRITKGDAADWWKKSFGDKIIIPWKEFKNTLHETHPIGSPLEAMALKSTIDLTCNDYISVFEFDVFCRLFQPWANLLRNWNVLAVTHPGYVAFLTYDEVKARLQKYINKPGSYVFRLSCTRLGQWAIGYVTTDRQILQTIPQNKSLCQALLDGQREGFFLYPDGRSVNPDLSNLVADSEEDHIRVTQEQYELYCEMGSTFQQCKICAENDKDIRLEPCGHLLCTPCLTQWQDSDGQGCPWCRCEIKGTEQVIVDPFDERQVLKAGSKTPTQDVD 431          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. TrEMBL
Match: A0A0N5C4F2 (Uncharacterized protein OS=Strongyloides papillosus OX=174720 PE=4 SV=1)

HSP 1 Score: 213.772 bits (543), Expect = 1.516e-55
Identity = 138/420 (32.86%), Postives = 223/420 (53.10%), Query Frame = 2
Query:   50 PIEMNSESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFI-NQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFR---KEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKY--DKRNCPFCNQKIQSTTKIV------NVKDPSKDVDAMKSAESV 1267
            P+    ++++  K   LL      + ++C K  L +      P+   +   +   L LIL  + S   + L    Y+    +N+ N      K  +DN   I  ++   R +   KV+ F  +Y+E+ A  P G +SP + +I+K  A  +W + FGD++ V  + F +  K+ + F  N  E  S K +++ TS +  + FEFD+FTRL+ PW+++L+ WRV+   HPAY+ F TY   K  L +++N+PG+YVFR+SC  LG W IGYV    ++ Q   +  +L++ALV+G +   Y YPNGE  NPDL+   E     K + V  E  ++Y      F+ CKIC E++KD++LE CGH IC++C    ++     +NCPFC  +I+   +IV      N+K+  K+ D     E +
Sbjct:   46 PLVSQDDAKVFDKTFRLL----DHVFKLCQKPKLKLK--PSPPNILEIIPDIYKHLNLILKENPSTYSEIL----YLRLYMSNLDNKCKGIIKLFKDNKDDIYEEESGTRLSLTKKVLSFSHMYYELIALSPEGKFSPKSFRITKQEASQFWHENFGDSLIVPWNQFENLLKKVHIFSDNTNESNSLKKTMDLTSNSHISQFEFDVFTRLFQPWDKLLDNWRVLAVKHPAYVSFLTYDQVKSKLEKFINKPGSYVFRLSCTRLGHWAIGYVAPDGKIYQTIPNNKSLVKALVDGYREGFYRYPNGEDNNPDLTKELEASTAGKTVHVTQEQFEIYCSIGSTFEMCKICDENDKDIRLEPCGHLICKTCLTSWQEVTTGTKNCPFCRCEIKGIEEIVIRKFSNNIKNIDKNKDGGGDDEII 455          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. TrEMBL
Match: A0A0P4W9Y5 (Uncharacterized protein OS=Scylla olivacea OX=85551 PE=4 SV=1)

HSP 1 Score: 211.46 bits (537), Expect = 1.777e-55
Identity = 127/408 (31.13%), Postives = 211/408 (51.72%), Query Frame = 2
Query:   77 IEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQST-TKIVNVKDPSKDVDAMKSAESVYMDMSE 1285
            IE++ +E       K+++ C +  + + +    P    +       L LI +     +L  LN+  Y      NM+      ++  ++   L+  +  H R+      + F  +  E++A FP G ++    +I+K  A  +W+K FG+   V    F     E +P     E  + K++I+ T  ++ + FEFD+FTRL+ PW  +L  W+++  +HP Y+ F TY + K  L +Y+N+PG+YVFR+SC  LG W IGYV S   + Q      +L +AL++G++   YLYP+G + NPDL+ + +   E  I V  E  +LY E    F+ CKIC E++KD+++E CGH +C  C  L +  + + CPFC  +I+ T T +V+  DP K       +    +DM E
Sbjct:   37 IERRTLEKTWKLMDKVVKQCQQSKMNLKNSP--PFILDILPDTYQHLRLIYN-KYENNLAALNSNEYFKVFVENMMRKCKQASRLFKEGKELMFDESSHYRRNLTKLSLVFSHMLSELKATFPQGSFAGDQFRITKGDAADFWKKCFGEKTVVPWRYFRDTLSEVHPIGPGLEAMALKSTIDLTCNDYISNFEFDVFTRLFQPWPTLLRNWQILAVTHPGYVAFLTYDEVKARLQKYINKPGSYVFRLSCTRLGQWAIGYVTSDGSILQTIPQNKSLCQALLDGHREGFYLYPDGRNLNPDLTWVAQATPEDHIKVTQEQYELYCEMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTLWQDSEGQGCPFCRAEIRGTETIVVDPFDPHKQHRTQSLSSGQLIDMEE 441          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. TrEMBL
Match: K1Q5V0 (E3 ubiquitin-protein ligase CBL-B OS=Crassostrea gigas OX=29159 GN=CGI_10010268 PE=4 SV=1)

HSP 1 Score: 211.075 bits (536), Expect = 2.302e-55
Identity = 123/383 (32.11%), Postives = 203/383 (53.00%), Query Frame = 2
Query:   77 IEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++KK IE       +++++C    + + +    P    +       L LI +    K L+ LN   Y      N++N   +  K  ++    +  ++ H R+      + F  +  E++A +PNG ++  N +I+K+ A  WW K FGD   V   +F     E +P  +  E  + K++I+ T  ++ + F+FD+FTRL+ PW  +L  W V+  +HP Y+ F TY + K  L +Y+ +PG+YVFR+SC  LG W IGYV    ++ Q      +L +AL++G +   + YP+G S NPDLS L +  +E  I V  E  +LY E    F+ CKIC E++KD+++E CGH +C  C    +  D + CPFC  +I+ T ++V
Sbjct:   36 VDKKTIEKSWKLMDRVVKLCQHPRMNLRNSP--PFILDLLPDTYQHLRLIYNKHDDK-LNTLNENDYFRVFIENLMNKCKATIKLFKEGKEKMFDENSHYRRNLTKLSLVFSHMLAELKAIYPNGQFAGDNFRITKSDAAEWWRKSFGDRTIVSWKMFRQTLHEAHPISSPLEAMALKSTIDLTCNDYISVFDFDVFTRLFQPWVNLLRNWNVLAVTHPGYVAFLTYDEVKARLQKYVTKPGSYVFRLSCTRLGQWAIGYVTVEGQILQTIPQNKSLCQALLDGQREGFFKYPDGRSINPDLSFLVQDCEEDHIKVTQEQYELYCEMGSTFQLCKICAENDKDIRIEPCGHLLCTPCLTQWQDSDGQGCPFCRCEIKGTEQVV 415          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Cavefish
Match: cbl (Cbl proto-oncogene [Source:NCBI gene;Acc:103032411])

HSP 1 Score: 200.29 bits (508), Expect = 2.453e-52
Identity = 117/383 (30.55%), Postives = 199/383 (51.96%), Query Frame = 2
Query:   77 IEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++KK +E       K++++C    L + +    P+   +       L  ILS    K ++ L +  Y      N++          ++    +  ++   R+      + F  +  E++A FP+G++   N +I+K  A  +W K FGD   V   +F     E +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  +L  W  +  +HP Y+ F TY + K  L +++++PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G +   YL+P+G + NPDL+ L E   +  I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ + + CPFC  +I+ T  IV
Sbjct:   35 VDKKTVEKCWKLMDKVVRLCQNPKLALKNSP--PYILDLLPDTYQHLRTILSRYEGK-METLGDNEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKAIFPSGLFQGDNFRITKADAAEFWRKSFGDKTIVQWKIFRQALHEFHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRTQNPDLTGLCEPSPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESEGQGCPFCRCEIKGTEPIV 414          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Cavefish
Match: cbl (Cbl proto-oncogene [Source:NCBI gene;Acc:103032411])

HSP 1 Score: 199.519 bits (506), Expect = 9.104e-52
Identity = 117/383 (30.55%), Postives = 199/383 (51.96%), Query Frame = 2
Query:   77 IEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            ++KK +E       K++++C    L + +    P+   +       L  ILS    K ++ L +  Y      N++          ++    +  ++   R+      + F  +  E++A FP+G++   N +I+K  A  +W K FGD   V   +F     E +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  +L  W  +  +HP Y+ F TY + K  L +++++PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G +   YL+P+G + NPDL+ L E   +  I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ + + CPFC  +I+ T  IV
Sbjct:   35 VDKKTVEKCWKLMDKVVRLCQNPKLALKNSP--PYILDLLPDTYQHLRTILSRYEGK-METLGDNEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKAIFPSGLFQGDNFRITKADAAEFWRKSFGDKTIVQWKIFRQALHEFHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRTQNPDLTGLCEPSPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESEGQGCPFCRCEIKGTEPIV 414          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Cavefish
Match: cblb (Cbl proto-oncogene B [Source:NCBI gene;Acc:103034711])

HSP 1 Score: 194.126 bits (492), Expect = 7.025e-50
Identity = 104/273 (38.10%), Postives = 157/273 (57.51%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWR-VIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  +  EI+A FP+G +     +I+K  A  +W + F +   V   VF     E +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +Y+N+PG+Y+FR+SC  LG W IGYV S   + Q       L +AL++G +   YL+P+G S NPDL+ L E      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ D + CPFC  +I+ T +I+
Sbjct:  150 FSHMLAEIKAIFPDGQFQGDTFRITKADAAEFWRRFFSEKTIVPWKVFRQCLHEMHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYINKPGSYIFRLSCTRLGQWAIGYVTSDGNILQTIPHNKPLFQALIDGCREGFYLFPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTERII 422          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Cavefish
Match: cblc (E3 ubiquitin-protein ligase CBL-like [Source:NCBI gene;Acc:103042889])

HSP 1 Score: 177.178 bits (448), Expect = 3.717e-46
Identity = 91/273 (33.33%), Postives = 151/273 (55.31%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTL--NEFRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  + +E++A FP+G +     K++K  A+ +W+K FG    V    F  + K  + F    E  + K++++ T  +  + FEFD+FTRL+ PW  +L  W ++  +HP Y+ F TY   +  L  + + PG+Y+FR+SC  +G W +G+V     + Q   + + L +AL++G +   YLYP+G   NPDL++L     +  + V  E  +LY E    F+ CKIC E +KD +++ CGH +C+ C    +K D   CP+C   I+ T  I+
Sbjct:  139 FSHMLWELRAMFPDGRFQGDIYKLTKTEAQEFWKKTFGYRCIVQWSQFKHQLKRVHGFEEGMEAMALKSTVDLTCNDHISVFEFDIFTRLFQPWSTLLRNWNQLAVTHPGYMAFLTYDQVRARLEHHRHRPGSYIFRLSCTRMGQWAVGHVTFDGSIVQTIPENTPLFQALIQGFREGCYLYPDGRDVNPDLTSLCMAPQKGRVKVTEEQYELYCEIGSTFQLCKICTERDKDTRIQPCGHLLCRPCLTGWQKSDGHTCPYCRCDIRGTESIL 411          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Cavefish
Match: cblc (E3 ubiquitin-protein ligase CBL-like [Source:NCBI gene;Acc:103042889])

HSP 1 Score: 177.178 bits (448), Expect = 3.717e-46
Identity = 91/273 (33.33%), Postives = 151/273 (55.31%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTL--NEFRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  + +E++A FP+G +     K++K  A+ +W+K FG    V    F  + K  + F    E  + K++++ T  +  + FEFD+FTRL+ PW  +L  W ++  +HP Y+ F TY   +  L  + + PG+Y+FR+SC  +G W +G+V     + Q   + + L +AL++G +   YLYP+G   NPDL++L     +  + V  E  +LY E    F+ CKIC E +KD +++ CGH +C+ C    +K D   CP+C   I+ T  I+
Sbjct:  139 FSHMLWELRAMFPDGRFQGDIYKLTKTEAQEFWKKTFGYRCIVQWSQFKHQLKRVHGFEEGMEAMALKSTVDLTCNDHISVFEFDIFTRLFQPWSTLLRNWNQLAVTHPGYMAFLTYDQVRARLEHHRHRPGSYIFRLSCTRMGQWAVGHVTFDGSIVQTIPENTPLFQALIQGFREGCYLYPDGRDVNPDLTSLCMAPQKGRVKVTEEQYELYCEIGSTFQLCKICTERDKDTRIQPCGHLLCRPCLTGWQKSDGHTCPYCRCDIRGTESIL 411          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Sea Lamprey
Match: cblc (Cbl proto-oncogene C, E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-080220-20])

HSP 1 Score: 94.3597 bits (233), Expect = 2.957e-21
Identity = 60/246 (24.39%), Postives = 119/246 (48.37%), Query Frame = 2
Query:   77 IEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVF 811
            ++K+ +E       K+++ C    + + +    P+   +       L L+L+    + +  L +  +     +N+++         ++    +  +  H R+      + F  +  E++A FPNG Y   + +I+K  A  +W + FGD   V    F     E +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  +L  W V+  +HP Y+ F TY + K  L +Y+++PG+Y++
Sbjct:   40 VDKRLVEKTWKLMDKVVRYCQNPKVQLKNSP--PYMLDILPDTYQHLRLVLARHDDR-MAALGDNEFFRVFIDNLLSKSKQAVNLFKEGKERMHDEHSHCRRNLTKLSLIFSHMLTELKAVFPNGSYQGDSFRITKADAADFWRRAFGDRTIVSWKAFRQCLHEVHPISSGLEAMALKSTIDLTCNDYISIFEFDIFTRLFQPWSSLLRNWNVLAVTHPGYMAFLTYDEVKARLQKYISKPGSYIY 282          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Sea Lamprey
Match: camk2a (calcium/calmodulin-dependent protein kinase II alpha [Source:ZFIN;Acc:ZDB-GENE-051113-72])

HSP 1 Score: 68.5514 bits (166), Expect = 2.983e-12
Identity = 26/58 (44.83%), Postives = 44/58 (75.86%), Query Frame = 3
Query: 3885 KNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNN 4058
            K +KQEI+K+TE L+ ++ +G++ ++ KL DP +T FEP+  GNL+ G++++KF F N
Sbjct:  262 KMRKQEIIKVTEQLIEAVNHGDFEAYTKLCDPGMTSFEPEALGNLVGGMEFHKFYFEN 319          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Nematostella
Match: EDO30537 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0H5])

HSP 1 Score: 142.51 bits (358), Expect = 8.757e-36
Identity = 64/151 (42.38%), Postives = 102/151 (67.55%), Query Frame = 3
Query: 3831 VKKSDKEMI----DNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSG 4271
             + SD+E++    D    +   K ++QEI++LT+ L++SI  G+Y ++ KLVDP +T FEP + GNL+EG++++KF F+N  SKR    +N +IL+P +H+LGED A I ++++ Q V+ +G     + EETR+WQ+K G W N+H H SG
Sbjct:  320 AQNSDEELMAHSEDEEGQDVTAKVREQEIIRLTQKLITSITTGDYDTYSKLVDPHVTCFEPFSNGNLVEGLEFHKFYFDNTLSKRSV-PINTTILSPHVHVLGEDAACICYMRLTQSVNSSGEAKTLQQEETRVWQKKGGNWINVHFHISG 469          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Nematostella
Match: EDO49898 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF52])

HSP 1 Score: 130.954 bits (328), Expect = 6.895e-32
Identity = 60/148 (40.54%), Postives = 101/148 (68.24%), Query Frame = 3
Query: 3834 KKSDKEMIDNI---SANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKS 4268
            K SD++ I  I      +    ++QEI++LT+ L++SI   ++ S+ KLVDP+IT FEP+  GN +EG++++KF F+N+ +KR+  +VN +IL P + +LGE+ A I++V++ Q +  +G     + EETR+WQ+K+G W N+H H+S
Sbjct:  326 KGSDEDSIATIIEEDTESTKTQREQEIIRLTQQLITSITAKDFDSYSKLVDPKITAFEPEALGNQVEGLEFHKFYFDNLPNKRNT-TVNTTILAPHVQMLGEEGACISYVRLTQGIGPDGLPRTTQSEETRVWQKKKGVWLNVHFHRS 472          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Medaka
Match: ENSORLT00000018206.2 (E3 ubiquitin-protein ligase CBL [Source:NCBI gene;Acc:101163758])

HSP 1 Score: 202.216 bits (513), Expect = 7.593e-53
Identity = 118/392 (30.10%), Postives = 202/392 (51.53%), Query Frame = 2
Query:   50 PIEMNSESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            P++ +  + ++KK +E       K++++C    + + +    P+   +       L  ILS    K ++ L    Y     +N+ N         ++    +  ++   R+      + F  +  E++A FPNG++   N +I+K  A  +W + FGD   V    F     E +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  +L  W  +  +HP Y+ F TY + K  L R++++PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G +   YL+P+G + NPDL+ L E   +  I V  E  +LY E    F+ CKIC E++KD+++E C H +C SC    ++ + + CPFC  +I+ T  IV
Sbjct:   25 PLQPHQPAVVDKKMVEKCWKLMDKVVRLCQNPKVALKNSP--PYILDLLPDTYQHLRTILSRYEGK-IEILGENEYFRVFIDNLTNKTKQTMSLFKEAKERMYEENSQPRRNLTKLSLIFSHMLAELKAIFPNGLFQGDNFRITKADAAEFWRRSFGDKTIVPWRTFRQALHEFHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQRFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGYREGFYLFPDGRAQNPDLTGLCEPSPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCRHLMCTSCLTAWQESEGQGCPFCRCEIKGTEPIV 413          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Medaka
Match: cbl (Cbl proto-oncogene [Source:NCBI gene;Acc:101170289])

HSP 1 Score: 194.897 bits (494), Expect = 2.868e-50
Identity = 118/385 (30.65%), Postives = 198/385 (51.43%), Query Frame = 2
Query:   77 IEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKE--IVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKR--NCPFCNQKIQSTTKIV 1213
            ++KK +E       K++++C    L + +    P+   +       L  ILS    K ++ L +  Y      N+           ++    +  ++   R+      + F  +  E++A FPNG++   N +I+K  A  +W + FGD   V   VF     E +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  +L  W  +  +HP Y+ F TY + K  L +++++PG+Y+FR+SC  LG W IGYV +   + Q       L +AL++G +   YL+P+G + NPDL+ L E   +  I V  E  +LY E    F+ CKIC E++KD+++E CGH +C SC    ++ + +   CPFC  +I+ T  IV
Sbjct:   35 VDKKTVEKCWKLMDKVVRLCQNPKLALKNSP--PYILDLLPDTYQHLRTILSRYDGK-METLGDNEYFRVFVENLTKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKAIFPNGLFQGDNFRITKADAAEFWRRAFGDKTIVPWKVFRQSLHEFHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRTQNPDLTGLCEPSPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESEGQGTGCPFCRCEIKGTEPIV 416          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Medaka
Match: cblb (Cbl proto-oncogene B [Source:NCBI gene;Acc:101157475])

HSP 1 Score: 186.422 bits (472), Expect = 1.163e-47
Identity = 121/394 (30.71%), Postives = 198/394 (50.25%), Query Frame = 2
Query:   68 ESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLKWQPHYST-VFKQLKSQLELILST-DTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVI-YSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNE--FRKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKI-VNVKDP 1228
            ++  ++K +E       K++++C    L    LK  P Y   +       L LIL   + ++ L  L+   Y     + ++N      +  ++    +  +    R+      + F  +  EI+A FP G +     +I+K  A  +W   FG+   V   VF     + +P  +  E  + K++I+ T  ++ + FEFD+FTRL+ PW  IL  W  +  +HP Y+ F TY + K  L +++N+PG+Y+FR+SC  LG W IGYV     + Q       L +AL++G +   YL+P+G S NPDL+ L +      I V  E  +LY E    F+ CKIC E++KD+++E CGH +C  C    ++ D + CPFC  +I+ T  I V+  DP
Sbjct:   38 QAAADRKTVEKTWKLMDKVVRLCQNPRL---QLKNSPPYILDILPDAYQHLRLILGKYEENQRLTQLSENEYFKIYIDGLMNKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKALFPGGQFQGDTFRITKADAADFWRTYFGEKTVVPWRVFRQCLHDVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLLKFINKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGFREGFYLFPDGRSYNPDLTDLCDPLPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTLCLTAWQESDGQGCPFCRCEIKGTAPITVDPFDP 428          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Medaka
Match: cblc (E3 ubiquitin-protein ligase CBL [Source:NCBI gene;Acc:101158476])

HSP 1 Score: 180.259 bits (456), Expect = 2.669e-47
Identity = 92/273 (33.70%), Postives = 156/273 (57.14%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEF--RKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  + +E++A FP G +     K++K+ A  +W + FG+   V  + F  + +  +PF  + E  + K++I+ T  ++ + FEFD+FTRL+ PW  ++  W  +  +HP Y+ F TY    + L  YL++PG+Y+FR+SC  +G W +G+V +  ++ Q     + L +AL++G K   YLYP+G   NP+L+ L E   ++ + V  E   LY E    F+ CKIC E +KD +++ CGH +C+SC    +K     CP+C   I+ T  ++
Sbjct:  136 FSHMLWELKAMFPGGHFQGDTYKLTKSKAEEFWRRSFGNKCIVPWNHFKQQLRTVHPFEERMEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLIRNWNHMAVTHPGYMAFLTYDQVVERLEHYLHKPGSYIFRLSCTRMGQWAVGHVTAEGDIIQTLPGDTPLYQALIQGFKEGCYLYPDGRDVNPELTCLCETAQKQTVQVTEEQYGLYCEIGSTFELCKICAEKDKDTRIKPCGHLLCKSCLFGWQKSVGNTCPYCRCDIKGTESVL 408          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Medaka
Match: cblc (E3 ubiquitin-protein ligase CBL [Source:NCBI gene;Acc:101158476])

HSP 1 Score: 180.259 bits (456), Expect = 2.669e-47
Identity = 92/273 (33.70%), Postives = 156/273 (57.14%), Query Frame = 2
Query:  407 FQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVW-RVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEF--RKEIVVNNEDLQLY-ECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIV 1213
            F  + +E++A FP G +     K++K+ A  +W + FG+   V  + F  + +  +PF  + E  + K++I+ T  ++ + FEFD+FTRL+ PW  ++  W  +  +HP Y+ F TY    + L  YL++PG+Y+FR+SC  +G W +G+V +  ++ Q     + L +AL++G K   YLYP+G   NP+L+ L E   ++ + V  E   LY E    F+ CKIC E +KD +++ CGH +C+SC    +K     CP+C   I+ T  ++
Sbjct:  136 FSHMLWELKAMFPGGHFQGDTYKLTKSKAEEFWRRSFGNKCIVPWNHFKQQLRTVHPFEERMEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLIRNWNHMAVTHPGYMAFLTYDQVVERLEHYLHKPGSYIFRLSCTRMGQWAVGHVTAEGDIIQTLPGDTPLYQALIQGFKEGCYLYPDGRDVNPELTCLCETAQKQTVQVTEEQYGLYCEIGSTFELCKICAEKDKDTRIKPCGHLLCKSCLFGWQKSVGNTCPYCRCDIKGTESVL 408          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Planmine SMEST
Match: SMESG000006795.1 (SMESG000006795.1)

HSP 1 Score: 753.821 bits (1945), Expect = 0.000e+0
Identity = 367/404 (90.84%), Postives = 371/404 (91.83%), Query Frame = 2
Query:  101 LCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEXXXXXXXXXXXXXXXXXXXEFDLFTRLYSPWERILEVWRVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKEIVVNNEDLQLYECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIVNVKDPSKDVDAMKSAESVYMDMSEPSRPNVEVR 1312
            +CDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDV                              ++ +  FDLFTRLYSPWERILEVWRVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKEIVVNNEDLQLYECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIVNVKDPSKDVDAMKSAESVYMDMSEPSRPNVEVR
Sbjct:    1 MCDTTQKLIQICNKKDLGVSDLKWQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNSFAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHNVKISKNPARMWWEKKFGDNIFVDLDV----------------------------RKYSLSKTFDLFTRLYSPWERILEVWRVIYSHPAYLHFSTYGDTKDTLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALVEGNKRNMYLYPNGESCNPDLSTLNEFRKEIVVNNEDLQLYECFDDFKECKICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIVNVKDPSKDVDAMKSAESVYMDMSEPSRPNVEVR 376          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Planmine SMEST
Match: SMESG000062800.1 (SMESG000062800.1)

HSP 1 Score: 321.627 bits (823), Expect = 5.920e-97
Identity = 171/172 (99.42%), Postives = 172/172 (100.00%), Query Frame = 3
Query: 3768 FSVAKSIXXXXXXXXXXXXXIVKKSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNAFL 4283
            FS+AKSITNSTSNQNNTQNTIVKKSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNAFL
Sbjct:  312 FSLAKSITNSTSNQNNTQNTIVKKSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNAFL 483          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Planmine SMEST
Match: SMESG000062800.1 (SMESG000062800.1)

HSP 1 Score: 298.516 bits (763), Expect = 1.501e-93
Identity = 144/144 (100.00%), Postives = 144/144 (100.00%), Query Frame = 3
Query: 3852 MIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNAFL 4283
            MIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNAFL
Sbjct:    1 MIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNAFL 144          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Planmine SMEST
Match: SMESG000062800.1 (SMESG000062800.1)

HSP 1 Score: 311.227 bits (796), Expect = 2.311e-93
Identity = 166/168 (98.81%), Postives = 167/168 (99.40%), Query Frame = 3
Query: 3768 FSVAKSIXXXXXXXXXXXXXIVKKSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSG 4271
            FS+AKSITNSTSNQNNTQNTIVKKSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKS 
Sbjct:  312 FSLAKSITNSTSNQNNTQNTIVKKSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSA 479          
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Planmine SMEST
Match: SMESG000029689.1 (SMESG000029689.1)

HSP 1 Score: 166.007 bits (419), Expect = 2.996e-43
Identity = 74/133 (55.64%), Postives = 102/133 (76.69%), Query Frame = 3
Query: 3879 DCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVGRGEETRIWQRKEGKWQNIHVHKSGNA 4277
            D + KKQE+LK+TE L S IA G+Y+SF KLVDPQIT FEP + GNL+EGI++ KF F+  ++KRD KS+N++IL+P +H+L +D A IA++KV Q VD+ G   V + EETR+W +KEGKW N+H H SG++
Sbjct:  343 DLRIKKQEVLKVTELLESHIATGDYASFAKLVDPQITYFEPLSKGNLMEGIEFQKFFFDTAFAKRDGKSININILSPAVHLLNDDNAFIAYIKVTQYVDRQGMPNVKQSEETRVWCKKEGKWMNVHWHSSGDS 475          
The following BLAST results are available for this feature:
BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CBLB1.109e-5132.22Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:... [more]
CBLB2.082e-5132.22Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:... [more]
CBLB3.358e-5132.22Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:... [more]
CBLB3.893e-5132.22Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:... [more]
CBLB4.001e-5132.22Cbl proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sli-12.405e-4228.91Suppressor of LIneage defect [Source:UniProtKB/Tr... [more]
sli-14.428e-4228.91Suppressor of LIneage defect [Source:UniProtKB/Tr... [more]
sli-15.801e-4228.91Suppressor of LIneage defect [Source:UniProtKB/Tr... [more]
unc-432.836e-3237.50Calcium/calmodulin-dependent protein kinase type I... [more]
unc-438.672e-3238.89Calcium/calmodulin-dependent protein kinase type I... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cbl3.140e-5631.20gene:FBgn0020224 transcript:FBtr0076614[more]
Cbl1.076e-5236.36gene:FBgn0020224 transcript:FBtr0076615[more]
CaMKII3.058e-3845.26gene:FBgn0264607 transcript:FBtr0300378[more]
CaMKII3.058e-3845.26gene:FBgn0264607 transcript:FBtr0100146[more]
CaMKII3.909e-3844.93gene:FBgn0264607 transcript:FBtr0300379[more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cbl1.937e-5231.12Cbl proto-oncogene, E3 ubiquitin protein ligase [S... [more]
cblb2.249e-4937.73Cbl proto-oncogene B, E3 ubiquitin protein ligase ... [more]
cblb2.279e-4937.73Cbl proto-oncogene B, E3 ubiquitin protein ligase ... [more]
cblb2.563e-4937.73Cbl proto-oncogene B, E3 ubiquitin protein ligase ... [more]
cblc3.418e-4934.80Cbl proto-oncogene C, E3 ubiquitin protein ligase ... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cblb8.635e-5131.01Cbl proto-oncogene B, E3 ubiquitin protein ligase ... [more]
cblb6.787e-5031.70Cbl proto-oncogene B, E3 ubiquitin protein ligase ... [more]
cblb7.021e-5031.01Cbl proto-oncogene B, E3 ubiquitin protein ligase ... [more]
cblb7.856e-5031.70Cbl proto-oncogene B, E3 ubiquitin protein ligase ... [more]
cblb9.349e-5031.70Cbl proto-oncogene B, E3 ubiquitin protein ligase ... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cblb3.483e-5132.22Casitas B-lineage lymphoma b [Source:MGI Symbol;Ac... [more]
Cblb3.483e-5132.22Casitas B-lineage lymphoma b [Source:MGI Symbol;Ac... [more]
Cblb4.687e-5132.22Casitas B-lineage lymphoma b [Source:MGI Symbol;Ac... [more]
Cblb4.687e-5132.22Casitas B-lineage lymphoma b [Source:MGI Symbol;Ac... [more]
Cblb7.909e-5039.26Casitas B-lineage lymphoma b [Source:MGI Symbol;Ac... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8K4S7|CBLB_RAT2.547e-5032.22E3 ubiquitin-protein ligase CBL-B OS=Rattus norveg... [more]
sp|Q3TTA7|CBLB_MOUSE3.278e-5032.22E3 ubiquitin-protein ligase CBL-B OS=Mus musculus ... [more]
sp|Q13191|CBLB_HUMAN4.230e-5032.22E3 ubiquitin-protein ligase CBL-B OS=Homo sapiens ... [more]
sp|Q9ULV8|CBLC_HUMAN1.043e-4935.48E3 ubiquitin-protein ligase CBL-C OS=Homo sapiens ... [more]
sp|Q6DFR2|CBLB_XENTR1.006e-4831.70E3 ubiquitin-protein ligase CBL-B OS=Xenopus tropi... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2C9KBL21.869e-5731.49Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A2C9KBE02.432e-5731.49Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A0N5C4F21.516e-5532.86Uncharacterized protein OS=Strongyloides papillosu... [more]
A0A0P4W9Y51.777e-5531.13Uncharacterized protein OS=Scylla olivacea OX=8555... [more]
K1Q5V02.302e-5532.11E3 ubiquitin-protein ligase CBL-B OS=Crassostrea g... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cbl2.453e-5230.55Cbl proto-oncogene [Source:NCBI gene;Acc:103032411... [more]
cbl9.104e-5230.55Cbl proto-oncogene [Source:NCBI gene;Acc:103032411... [more]
cblb7.025e-5038.10Cbl proto-oncogene B [Source:NCBI gene;Acc:1030347... [more]
cblc3.717e-4633.33E3 ubiquitin-protein ligase CBL-like [Source:NCBI ... [more]
cblc3.717e-4633.33E3 ubiquitin-protein ligase CBL-like [Source:NCBI ... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
cblc2.957e-2124.39Cbl proto-oncogene C, E3 ubiquitin protein ligase ... [more]
camk2a2.983e-1244.83calcium/calmodulin-dependent protein kinase II alp... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO305378.757e-3642.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO498986.895e-3240.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000018206.27.593e-5330.10E3 ubiquitin-protein ligase CBL [Source:NCBI gene;... [more]
cbl2.868e-5030.65Cbl proto-oncogene [Source:NCBI gene;Acc:101170289... [more]
cblb1.163e-4730.71Cbl proto-oncogene B [Source:NCBI gene;Acc:1011574... [more]
cblc2.669e-4733.70E3 ubiquitin-protein ligase CBL [Source:NCBI gene;... [more]
cblc2.669e-4733.70E3 ubiquitin-protein ligase CBL [Source:NCBI gene;... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II subunit delta vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000006795.10.000e+090.84SMESG000006795.1[more]
SMESG000062800.15.920e-9799.42SMESG000062800.1[more]
SMESG000062800.11.501e-93100.00SMESG000062800.1[more]
SMESG000062800.12.311e-9398.81SMESG000062800.1[more]
SMESG000029689.12.996e-4355.64SMESG000029689.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015021 ID=SMED30015021|Name=Calcium/calmodulin-dependent protein kinase type II subunit delta|organism=Schmidtea mediterranea sexual|type=transcript|length=4551bp
GTCTTAATTTTCTTTAACGATGCATCGAAATAAATCATTGAAATTAATAC
CGATAGAAATGAATAGTGAATCAAGAATCGAGAAGAAGCAAATAGAACTA
CTGTGCGATACAACACAAAAATTGATACAAATTTGCAATAAAAAAGATTT
GGGAGTCTCGGATCTTAAATGGCAACCTCATTATTCAACAGTCTTTAAAC
AATTAAAAAGCCAATTAGAATTAATTTTATCCACTGATACTAGCAAATCA
TTAGATTATTTAAACAATATTCCATATATTTTACAATTGAAAAATAACAT
GATTAATTTATATAACTCTTTTGCCAAATTTGTTCAGGACAATGGACCTT
TAATTGGTACTAAAGATGATCATATGAGAAAAACATTCTTCACGAAAGTT
GTACATTTTCAATTTCTGTATTTTGAAATTCAAGCATATTTCCCGAACGG
AATCTACAGTCCACACAATGTCAAAATATCAAAAAACCCTGCTAGAATGT
GGTGGGAAAAGAAATTCGGCGACAACATTTTTGTTGATTTAGACGTGTTT
GTTTCCAAATTTAAAGAGGATTACCCATTCATAAACCAGGCGGAAATATT
CTCTTTCAAAAACAGTATTAACTTTACCTCAACCAATTTCACAACAACAT
TTGAGTTTGATTTGTTTACGCGTTTATATTCTCCATGGGAACGAATTTTA
GAAGTTTGGAGGGTAATATATTCCCACCCAGCCTATTTACACTTTAGCAC
TTATGGAGATACTAAAGATACACTCAGTAGATATTTAAATGAACCAGGAA
CATATGTATTTCGAATCAGTTGCAAAGATTTAGGGTTCTGGACCATCGGC
TATGTGAAATCATCCAAAGAAATGGGCCAAGTCAAAGTTGACAAAAGTAA
TTTAATAGAGGCACTTGTGGAAGGAAATAAAAGAAATATGTATCTTTATC
CAAACGGAGAAAGTTGTAATCCTGATTTGTCCACTCTAAATGAATTCAGG
AAAGAAATTGTTGTAAATAATGAAGACCTTCAATTGTATGAATGTTTCGA
TGATTTCAAAGAATGTAAAATTTGTCGAGAATCAGAAAAAGATCTTCAAC
TGGAAAGTTGTGGTCATCAAATTTGTCAAAGTTGTTACAAACTATTGCGA
AAATACGATAAAAGGAACTGTCCATTTTGTAACCAAAAGATTCAATCAAC
AACTAAAATCGTTAACGTAAAAGATCCTTCTAAAGATGTTGATGCAATGA
AATCTGCAGAAAGTGTTTATATGGATATGTCAGAGCCGTCGAGACCAAAC
GTGGAAGTCAGGTAAGTTTTCTTGAAAACTTAATTATTTGTTCAAATTAT
CAGAATGAGACTTAATATTTTTTGAAAGTCTTTTGATCTAATTTATTTTT
TCCCCTTTTCAAATCTCATTGAAATTATATTTATTTCTTCTCCTAGTTCT
TTTTTTGAAATCTTTAACTTTTACCAATAAATGCTTGAAACCTTAATGCT
TATTTTCTAGTATGCTGGATTAAGCAATTATTTACTGTTTTCTATATATG
CGAGATTTTTCCAATTTTTAGATAAATCAACATTAGAACTAAGATAGAAG
TAGAAAAAGAAAAAAAGAAATTTATTAAAGCTATGTTAATTAGTCAAGTA
TTATTTGAGTTACAGTTTAAATGGTTTCGAAATGTTGATGGAAAGGAAAC
AAACTAAAATACCATTTAAATTGATCGAATTTTAAGTAAATTGAATGTTG
GGAGTTCTTTTTTCAAACGCACTGCATTCTATGTAGGGGTCGCAAAATTC
GGTAAATTTCACATTCCGGTATTCGGTATATAGATTTGTCACTAATATAA
TTTAAACAAATATATCAATTTGTAACTGTATTTTCTTATAATTAGATATT
AGATAGAATATTTTGATAGATAGAATGACTGCTGACAAGAAATATTTTGC
CAAAAATATGCACATAAAAACAATAACTACACAAAGTATTGTCGACCAAG
CAAGATCTTATTTTGATACAAAACAATCCTTCTGTTGAATATGTCCTCTT
TGCTCTCACGCTGGTTAAATAAGTTCTTAGTATTTTTCTTTGGTTTTATA
CTCACAAAACAAACTCATCTCTTTTTTATTTTTAATCTTTCAGCTTTTGA
TGAGAAGTATCGTGATTGAGAGATGTTTTCATGAATATTTTATTCCAATC
TTTCTTTCATTGATAAAACGTTTTATTCGTCTTGTGGTAAGTCGATTCAT
ATATATTGGTCACTTTTTTAAATTGTGTAAGAAATCTAGTAGATCAGAGT
ATATGGTTCGTCTTTCTTTGATGTTTTGAATTAAATTTCCTTTGAGCGTA
ACACTCAGTATATTATTTTGGATAGATACTTCATTGAGTCATTACAGTTA
AGGTAACATCGGCTACTGCAATATTTGCACTTATTAAATACAGGGCTTTT
AGTTCACTTTTTTCAAAACCAAAATTAGTTTATATATAAAATAAAGATTT
CCTTACACAATCACGGATTTCATAAAACTTTTCTAACATCTTTCACAAAC
TGTTTTTCATCTGGTTTTAGAATCAAAAATAAAATGCTTTTCTCTTCCAT
AGTGCGATGTGACATGTTTCTGTGCGATATTATTTCTTGTAGGTCATTTC
CGAAATATTTTCACTCCAGGACGATTTGTTTAAATAAATAGAATATAATA
AATGAAATTTTGATTGGCCATTATTTTTAACATTTTACGAGTTCGTTTTC
AGAATAATTACTAAACTTATTTATGTATGTTTATCGGTCGAAATATTTCA
TATTTTATGAATAAACATTGCGGAAATTGACTACCATTGTTATTAATTTA
AATTTTATTTATATTGTACGAGGGTCATCTTGTATTAATAATGGATAAGG
TATAGAAATAAATAATAGTCAATGATGCCATAAAATCAATATGCACTATT
ATTGGAATAATAGAATACTATCCTACAAGAGATGAAAATATTCATTTTAT
TAGAAACGAAGTTAATTATAAATACAATTTTCTGGGCGGCGAATAAAGCA
TTCTAATTATAGTTCTAAAAATAGTCAAAACATTTTTATAATAAAACTAA
ATCTATTCATGCTCGTTTGTATTTACTAAAAAAACATCATTCAGTTTTCC
TACCGGCTTTATTACGCATTTTTGTGCATAATTTATTATTATTATTTATG
TTTTCCATTCCGCGCCTAATAATGGCATTTCTAGAAAATCAATACTGAAA
ATTCTATTCTGAAAATAATACTGATAATAGTTAAGTACTGTTGAAATTTC
ATTTCTGAAATATATTTATCGCTTTCATATTATTATTATGATTATGATTA
TTATTATGATTATTATTAATTTTGGTGTGGAATTCTATTCGATGGAATTA
TTTGCAGATATATAAAGGGAGATTGTCTATTTTATTAGTTAAATAAGTCC
TAATGAAACCAACTGTTTCTGGATTCAGGAAAGATAAATTAATAGATTGA
AACTCATAGAAATACGATTTATAATCAAACCGTACCAATTAAAAGGAATT
TTATTTTAACGATATTGTCAGTAGTATATCATAAATATATCATATCTATT
CTTGAGGCAATCACGAAAAATGTCCTCTGATAGAATATGTTAAATGAATT
TATTCTATTGTAAAATAGACTATTTCCACAATTGCTGTTGTTGTCTGGCA
TAAATGGAATTCTATTATGAATTAATTTTATCTCGTCTTTAATTGGCTTA
TGAGTTTTTGTTCCATGTTTTCAGTAGCTAAAAGCATCACTAACAGTACT
TCCAATCAAAACAATACCCAGAATACTATTGTTAAGAAATCTGACAAAGA
AATGATAGACAATATCTCTGCAAATGCTGATTGTAAAAATAAGAAACAAG
AAATTCTCAAATTGACAGAAAATCTTTTGTCTTCAATCGCCAATGGCAAT
TATTCATCGTTCATCAAGTTGGTTGATCCCCAAATTACGGTTTTTGAACC
AGACACTTGTGGAAATCTTATTGAAGGAATCGATTATTATAAGTTTTTGT
TTAATAATGTTTATTCTAAAAGAGATGCCAAGTCTGTAAATATGAGTATT
CTTAATCCCACAATTCATATTCTTGGAGAAGATTGCGCTTCAATTGCATT
TGTAAAAGTTGTTCAAATTGTTGATAAAAACGGTTCTGTTACTGTTGGTA
GAGGTGAGGAAACACGAATTTGGCAACGGAAGGAAGGTAAATGGCAAAAT
ATTCATGTCCACAAATCTGGTAATGCCTTTCTTTGATAAATTTCTCGAAA
TATTAATCAAAATGAAAGCGAAATAAATATGAATATAATAACTCTGTTGG
TGCCGATTTCCAACTGGTATAATTCAAATATTCAGTGAAATTTCTCTCTC
TATCTCTATTGACAATGGTTTTTATCTTTTTACTGAAATTATTATGAATA
TTATTAAAATTGTTACTATTTTTTCCTGACTTGTTCTCTGCTATTTACTT
AGTATTCATGATCTCATTTGTTTTTCTAAGACAGCTTTATTGTTTTTTGT
G
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protein sequence of SMED30015021-orf-1

>SMED30015021-orf-1 ID=SMED30015021-orf-1|Name=SMED30015021-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=179bp
MSFCSMFSVAKSITNSTSNQNNTQNTIVKKSDKEMIDNISANADCKNKKQ
EILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFL
FNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDKNGSVTVG
RGEETRIWQRKEGKWQNIHVHKSGNAFL*
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protein sequence of SMED30015021-orf-2

>SMED30015021-orf-2 ID=SMED30015021-orf-2|Name=SMED30015021-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=432bp
MHRNKSLKLIPIEMNSESRIEKKQIELLCDTTQKLIQICNKKDLGVSDLK
WQPHYSTVFKQLKSQLELILSTDTSKSLDYLNNIPYILQLKNNMINLYNS
FAKFVQDNGPLIGTKDDHMRKTFFTKVVHFQFLYFEIQAYFPNGIYSPHN
VKISKNPARMWWEKKFGDNIFVDLDVFVSKFKEDYPFINQAEIFSFKNSI
NFTSTNFTTTFEFDLFTRLYSPWERILEVWRVIYSHPAYLHFSTYGDTKD
TLSRYLNEPGTYVFRISCKDLGFWTIGYVKSSKEMGQVKVDKSNLIEALV
EGNKRNMYLYPNGESCNPDLSTLNEFRKEIVVNNEDLQLYECFDDFKECK
ICRESEKDLQLESCGHQICQSCYKLLRKYDKRNCPFCNQKIQSTTKIVNV
KDPSKDVDAMKSAESVYMDMSEPSRPNVEVR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0004672protein kinase activity
GO:0004674protein serine/threonine kinase activity
GO:0005524ATP binding
GO:0016301kinase activity
GO:0016740transferase activity
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0004871signal transducer activity
GO:0005509calcium ion binding
GO:0001784phosphotyrosine binding
GO:0005516calmodulin binding
GO:0004683calmodulin-dependent protein kinase activity
GO:0004842ubiquitin-protein transferase activity
GO:0016874ligase activity
Vocabulary: cellular component
TermDefinition
GO:0005886plasma membrane
GO:0016020membrane
GO:0016529sarcoplasmic reticulum
GO:0033017sarcoplasmic reticulum membrane
GO:0042383sarcolemma
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0010613positive regulation of cardiac muscle hypertrophy
GO:0016310phosphorylation
GO:0060341regulation of cellular localization
GO:0007166cell surface receptor signaling pathway
GO:0006468protein phosphorylation
GO:0016567protein ubiquitination
GO:0023051regulation of signaling
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR001841Znf_RING
IPR011992EF-hand-dom_pair
IPR013083Znf_RING/FYVE/PHD
IPR000980SH2
IPR003153Adaptor_Cbl_N_hlx
IPR014742Adaptor_Cbl_SH2-like
IPR014741Adaptor_Cbl_EF_hand-like
IPR017907Znf_RING_CS
IPR024159Cbl_PTB
IPR032710NTF2-like_dom_sf
IPR013543Ca/CaM-dep_prot_kinase-assoc