GTP-binding protein

Overview
NameGTP-binding protein
Smed IDSMED30015015
Length (bp)1146
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of GTP-binding protein (SMED30015015) t-SNE clustered cells

Violin plots show distribution of expression levels for GTP-binding protein (SMED30015015) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GTP-binding protein (SMED30015015) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GTP-binding protein (SMED30015015) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30015015

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
headSMED30015015SMESG000055098.1 SmedASXL_008436SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
headSMED30015015SMESG000055098.1 dd_Smed_v6_37931_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of GTP-binding protein vs. Ensembl Human
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 91.2781 bits (225), Expect = 6.002e-21
Identity = 60/178 (33.71%), Postives = 93/178 (52.25%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIE-YHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSPK 798
            V +FG+G  GK+S++ RF+  +F  SY PT+ED T RQ I+       +Q  DT   ++FPAM  + I K  AFILV S+T   SL  L  ++ QI   +G    I  P+M+V NK D    R +     +   +        F+ TSAK N  ++ +F+ L   + R +++ ++  K
Sbjct:   10 VAVFGAGGVGKSSLVLRFVKGTFRESYIPTVED-TYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESI--PIMLVGNKCDESPSREVQSSEAEALARTWKCA---FMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGK 181          
BLAST of GTP-binding protein vs. Ensembl Human
Match: RAP1B (RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857])

HSP 1 Score: 90.1225 bits (222), Expect = 9.011e-21
Identity = 52/169 (30.77%), Postives = 88/169 (52.07%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +  +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Human
Match: RAP1B (RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857])

HSP 1 Score: 90.1225 bits (222), Expect = 9.011e-21
Identity = 52/169 (30.77%), Postives = 88/169 (52.07%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +  +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Human
Match: RAP1B (RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857])

HSP 1 Score: 90.1225 bits (222), Expect = 9.011e-21
Identity = 52/169 (30.77%), Postives = 88/169 (52.07%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +  +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Human
Match: RAP1B (RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857])

HSP 1 Score: 90.1225 bits (222), Expect = 9.011e-21
Identity = 52/169 (30.77%), Postives = 88/169 (52.07%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +  +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Celegans
Match: ssr-2 (Sperm-Specific family, class R [Source:UniProtKB/TrEMBL;Acc:O02139])

HSP 1 Score: 100.523 bits (249), Expect = 9.260e-24
Identity = 57/162 (35.19%), Postives = 93/162 (57.41%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLW 753
            +V+ GS K GKT+I+ R+L+  F + Y  TIED+ +R+F   G+   +  +DT   + FP M  + I  A AF+LV SV D  S   + +++ +I S R  D +   P++VV NK D  +++I   E   K    R  ++ ++I  SAK+NI I ++F++L 
Sbjct:    8 LVVLGSAKVGKTNIIRRYLYNEFSSKYKETIEDLHSREFRIQGVPLPLDILDTN--FNFPDMRRLSIASASAFLLVFSVDDVTSFKEMSDIWQEICSRRS-DLNEL-PIVVVGNKCDVENKKIY--EETAKAFTNRLSSDVRYIEVSAKDNIRITDVFRTLL 163          
BLAST of GTP-binding protein vs. Ensembl Celegans
Match: rap-1 (Ras-related protein Rap-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18246])

HSP 1 Score: 95.1301 bits (235), Expect = 5.917e-23
Identity = 58/202 (28.71%), Postives = 103/202 (50.99%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEE---KFINTSAKNNIGIENIFKSLWYQ---KYRHSLNRELSPKHDYFTLAQSLRRCSDAIII 855
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F+LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ ++      Q +N+  +    F+ TSAK  I +  +F  L  Q   +Y  S  R+           QS ++C   +I+
Sbjct:    6 IVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLMDLRDQILRVKDTD---EVPMILVGNKCDLEDERVVGKD------QGQNLARQFGSAFLETSAKAKINVSEVFYDLVRQINRRYPESGRRQ----------GQSNKQCCSCVIM 188          
BLAST of GTP-binding protein vs. Ensembl Celegans
Match: drn-1 (GTP-binding protein drn-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09930])

HSP 1 Score: 90.5077 bits (223), Expect = 7.064e-21
Identity = 62/172 (36.05%), Postives = 89/172 (51.74%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIE--YHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSL 777
            V +FG+G  GK+SI  RF+  +F  +Y PTIED T RQ I+   +    +Q  DT   ++FPAM  + I K  AFIL+ SVT+  S   L  +   +   +G      +P+M+V NK D   +R +S  +  K        E  FI TSAKNN  I  +F+ L   + +  L
Sbjct:   33 VAVFGAGGVGKSSITQRFVKGTFNENYVPTIED-TYRQVISCNQKNVCTLQITDTTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKGNAIA-ETPIMLVGNKKDEESKREVSSNSGQKVATNM---ECGFIETSAKNNENITELFQQLLALEKKRQL 199          
BLAST of GTP-binding protein vs. Ensembl Celegans
Match: D1081.4 (pep chromosome:WBcel235:I:8474886:8476282:-1 gene:WBGene00008382.1 transcript:D1081.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:D1081.4)

HSP 1 Score: 80.1073 bits (196), Expect = 3.177e-17
Identity = 43/124 (34.68%), Postives = 70/124 (56.45%), Query Frame = 1
Query:  262 ITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQF-ITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKID--CL 624
            +TV + G+ + GK++++S+FLW  F   Y PT+E+    ++ I  G    VQ ID+    +F  M N+YI  A AF++V +  D++SL    +  + I + RG       P+++VANK D  CL
Sbjct:   23 VTVAVLGAERVGKSAMVSQFLWHKFVEDYRPTVEEFNWIEYEIEEGRVLMVQIIDSSGSRDFIGMKNLYIGTADAFLVVFAADDASSLEEALSTLSDIHARRGNSV----PVLLVANKTDKPCL 142          
BLAST of GTP-binding protein vs. Ensembl Celegans
Match: ras-2 (GTP binding protein; R-RAS related [Source:UniProtKB/TrEMBL;Acc:G5EGA7])

HSP 1 Score: 78.5666 bits (192), Expect = 9.476e-17
Identity = 54/163 (33.13%), Postives = 86/163 (52.76%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIIS-QETIDKWLQYRNINEEKFINTSAKN-NIGIENIFKSL 750
            +V+ G G  GK+S+  +F  + F   Y+PTIED   +    +G    +  +DT    EF AM   YI   + F+LV SVT+  S      ++ Q+   R KD   Y P+++VANK+D ++QR++S QE  +   Q + +    +I TSAK   + ++  F  L
Sbjct:   20 LVVIGDGGVGKSSLTIQFFQKQFVDYYDPTIEDQYIQHCEIDGNWVIMDVLDTAGQEEFSAMREQYIRGGRGFLLVFSVTERKSFEEAHKLYNQVL--RVKDRSEY-PVLLVANKVDLINQRVVSEQEGRELAAQLKLM----YIETSAKEPPVNVDAAFHEL 175          
BLAST of GTP-binding protein vs. Ensembl Fly
Match: CG13375 (gene:FBgn0040370 transcript:FBtr0342963)

HSP 1 Score: 97.8265 bits (242), Expect = 6.262e-23
Identity = 58/171 (33.92%), Postives = 86/171 (50.29%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNIN-------EEKFINTSAKNNIGIENIFKSLWYQ 759
            +V+ GS K GKTSI+++FL+ +F T Y  TIE++    F   G+   +  +DT   YEFPAM  + I  A AFILV  VTD+ +   +  +  QI   +        P++VV NKID L     +    ++ ++Y           E  F+  SA +N  I  +FK L  Q
Sbjct:   21 IVVMGSAKVGKTSIITQFLYNTFSTKYKRTIEEMHQGNFSIAGVSLTLDILDTAGSYEFPAMRALSISSADAFILVYDVTDATTFEEVRTIRDQIHETKAT---TAVPIVVVGNKIDLL-----ADGETEREVEYATTESVVTVDWENGFVEASASSNENITQVFKELLAQ 183          
BLAST of GTP-binding protein vs. Ensembl Fly
Match: CG13375 (gene:FBgn0040370 transcript:FBtr0070103)

HSP 1 Score: 97.8265 bits (242), Expect = 8.827e-23
Identity = 58/171 (33.92%), Postives = 86/171 (50.29%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNIN-------EEKFINTSAKNNIGIENIFKSLWYQ 759
            +V+ GS K GKTSI+++FL+ +F T Y  TIE++    F   G+   +  +DT   YEFPAM  + I  A AFILV  VTD+ +   +  +  QI   +        P++VV NKID L     +    ++ ++Y           E  F+  SA +N  I  +FK L  Q
Sbjct:   50 IVVMGSAKVGKTSIITQFLYNTFSTKYKRTIEEMHQGNFSIAGVSLTLDILDTAGSYEFPAMRALSISSADAFILVYDVTDATTFEEVRTIRDQIHETKAT---TAVPIVVVGNKIDLL-----ADGETEREVEYATTESVVTVDWENGFVEASASSNENITQVFKELLAQ 212          
BLAST of GTP-binding protein vs. Ensembl Fly
Match: CG13375 (gene:FBgn0040370 transcript:FBtr0300326)

HSP 1 Score: 97.8265 bits (242), Expect = 8.827e-23
Identity = 58/171 (33.92%), Postives = 86/171 (50.29%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNIN-------EEKFINTSAKNNIGIENIFKSLWYQ 759
            +V+ GS K GKTSI+++FL+ +F T Y  TIE++    F   G+   +  +DT   YEFPAM  + I  A AFILV  VTD+ +   +  +  QI   +        P++VV NKID L     +    ++ ++Y           E  F+  SA +N  I  +FK L  Q
Sbjct:   50 IVVMGSAKVGKTSIITQFLYNTFSTKYKRTIEEMHQGNFSIAGVSLTLDILDTAGSYEFPAMRALSISSADAFILVYDVTDATTFEEVRTIRDQIHETKAT---TAVPIVVVGNKIDLL-----ADGETEREVEYATTESVVTVDWENGFVEASASSNENITQVFKELLAQ 212          
BLAST of GTP-binding protein vs. Ensembl Fly
Match: CG30158 (gene:FBgn0050158 transcript:FBtr0086165)

HSP 1 Score: 95.5153 bits (236), Expect = 3.953e-22
Identity = 53/165 (32.12%), Postives = 86/165 (52.12%), Query Frame = 1
Query:  262 ITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKID-CLDQRIISQETIDKWLQYRNIN-EEKFINTSAKNNIGIENIFKSL 750
            I +V+ G    GK+SI+ RFL++++   Y  T+ED+ NR++   G+   V  +DT    +FPAM  + I  A AF+LV + T + S   +   F +I  +RG DF    P+++  NK D     R +  E +  W+         K +  SAK +  + ++FKSL
Sbjct:    7 IRLVLLGGAGVGKSSIVKRFLFKTYTDKYRATVEDLYNREYDLGGVTLKVDILDTSGDMQFPAMRRLSIATAHAFMLVYAATSAPSFQCVKQCFEEIREQRG-DFQDI-PIVIAGNKADLATTHREVKLEEVTDWVFCELPRLRAKVLECSAKEDSNVTDLFKSL 169          
BLAST of GTP-binding protein vs. Ensembl Fly
Match: Rap1 (gene:FBgn0004636 transcript:FBtr0303154)

HSP 1 Score: 90.8929 bits (224), Expect = 2.611e-21
Identity = 50/164 (30.49%), Postives = 87/164 (53.05%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F+LV S+T  ++ N L ++  QI   +  D     P+++V NK D  ++R++ +E         N     F+ TSAK  + + +IF  L  Q
Sbjct:    6 IVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTD---DVPMVLVGNKCDLEEERVVGKELGKNLATQFNC---AFMETSAKAKVNVNDIFYDLVRQ 163          
BLAST of GTP-binding protein vs. Ensembl Zebrafish
Match: rap1b (RAP1B, member of RAS oncogene family [Source:NCBI gene;Acc:321107])

HSP 1 Score: 92.8189 bits (229), Expect = 6.373e-22
Identity = 53/169 (31.36%), Postives = 89/169 (52.66%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNSCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Zebrafish
Match: rap1ab (RAP1A, member of RAS oncogene family b [Source:ZFIN;Acc:ZDB-GENE-040426-2738])

HSP 1 Score: 92.4337 bits (228), Expect = 9.874e-22
Identity = 55/169 (32.54%), Postives = 91/169 (53.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I + +IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNL--ARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Zebrafish
Match: rap1ab (RAP1A, member of RAS oncogene family b [Source:ZFIN;Acc:ZDB-GENE-040426-2738])

HSP 1 Score: 92.4337 bits (228), Expect = 9.874e-22
Identity = 55/169 (32.54%), Postives = 91/169 (53.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I + +IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNL--ARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Zebrafish
Match: rap1ab (RAP1A, member of RAS oncogene family b [Source:ZFIN;Acc:ZDB-GENE-040426-2738])

HSP 1 Score: 92.4337 bits (228), Expect = 9.874e-22
Identity = 55/169 (32.54%), Postives = 91/169 (53.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I + +IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNL--ARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Zebrafish
Match: rap1ab (RAP1A, member of RAS oncogene family b [Source:ZFIN;Acc:ZDB-GENE-040426-2738])

HSP 1 Score: 92.4337 bits (228), Expect = 9.874e-22
Identity = 55/169 (32.54%), Postives = 91/169 (53.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I + +IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNL--ARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Xenopus
Match: rap1b (RAP1B, member of RAS oncogene family [Source:NCBI gene;Acc:493557])

HSP 1 Score: 92.8189 bits (229), Expect = 1.036e-21
Identity = 53/169 (31.36%), Postives = 89/169 (52.66%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Xenopus
Match: aldh1a3 (aldehyde dehydrogenase 1 family member A3 [Source:Xenbase;Acc:XB-GENE-992885])

HSP 1 Score: 92.0485 bits (227), Expect = 2.193e-21
Identity = 55/169 (32.54%), Postives = 89/169 (52.66%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q    G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVEGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNL--ARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Xenopus
Match: pnp (purine nucleoside phosphorylase [Source:Xenbase;Acc:XB-GENE-1011598])

HSP 1 Score: 90.8929 bits (224), Expect = 6.060e-21
Identity = 61/178 (34.27%), Postives = 97/178 (54.49%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIE-YHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQET---IDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNREL 789
            VV+FG+   GK+S++ RF+  +F  +Y PTIED T RQ I+       +Q  DT   ++FPAM  + I K  AFILV SVT   S+  L  ++ QI   +G   +I  P+M+V NK D   + + + E     +KW       +  F+ TSAK N  ++ +F+ L   + R +++ ++
Sbjct:   10 VVVFGAAGVGKSSLVLRFVRGTFRETYIPTIED-TYRQVISCDKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVTSKQSMEELQPIYEQICQIKGDTQNI--PIMLVGNKSDETLREVQASEGECLANKW-------KCSFMETSAKLNYNVQELFQELLNLEKRRTVSLQV 177          
BLAST of GTP-binding protein vs. Ensembl Xenopus
Match: aldh1a3 (aldehyde dehydrogenase 1 family member A3 [Source:Xenbase;Acc:XB-GENE-992885])

HSP 1 Score: 87.4261 bits (215), Expect = 6.209e-20
Identity = 50/158 (31.65%), Postives = 84/158 (53.16%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIF 741
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q    G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  + 
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVEGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNL--ARQWNNCAFLESSAKSKINVNEVI 158          
BLAST of GTP-binding protein vs. Ensembl Xenopus
Match: aldh1a3 (aldehyde dehydrogenase 1 family member A3 [Source:Xenbase;Acc:XB-GENE-992885])

HSP 1 Score: 87.0409 bits (214), Expect = 9.445e-20
Identity = 51/158 (32.28%), Postives = 84/158 (53.16%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIF 741
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q    G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +   F
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVEGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEDF 158          
BLAST of GTP-binding protein vs. Ensembl Mouse
Match: Diras2 (DIRAS family, GTP-binding RAS-like 2 [Source:MGI Symbol;Acc:MGI:1915453])

HSP 1 Score: 90.8929 bits (224), Expect = 4.887e-21
Identity = 60/178 (33.71%), Postives = 93/178 (52.25%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIE-YHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSPK 798
            V +FG+G  GK+S++ RF+  +F  SY PT+ED T RQ I+       +Q  DT   ++FPAM  + I K  AFILV S+T   SL  L  ++ QI   +G    I  P+M+V NK D    R +     +   +        F+ TSAK N  ++ +F+ L   + R +++ ++  K
Sbjct:   10 VAVFGAGGVGKSSLVLRFVKGTFRESYIPTVED-TYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESI--PIMLVGNKCDESPNREVQSSEAEALARTWKCA---FMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGK 181          
BLAST of GTP-binding protein vs. Ensembl Mouse
Match: Rap1b (RAS related protein 1b [Source:MGI Symbol;Acc:MGI:894315])

HSP 1 Score: 90.1225 bits (222), Expect = 6.187e-21
Identity = 52/169 (30.77%), Postives = 88/169 (52.07%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +  +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Mouse
Match: Rap1a (RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852])

HSP 1 Score: 88.5817 bits (218), Expect = 2.600e-20
Identity = 54/173 (31.21%), Postives = 92/173 (53.18%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEE----KFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +  +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E      Q +N+  +     F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKE------QGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Mouse
Match: Rap1a (RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852])

HSP 1 Score: 86.6557 bits (213), Expect = 7.387e-20
Identity = 51/162 (31.48%), Postives = 88/162 (54.32%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEE----KFINTSAKNNIGIENIF 741
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +  +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E      Q +N+  +     F+ +SAK+ I +  IF
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKE------QGQNLARQWCNCAFLESSAKSKINVNEIF 158          
BLAST of GTP-binding protein vs. Ensembl Mouse
Match: Rasd1 (RAS, dexamethasone-induced 1 [Source:MGI Symbol;Acc:MGI:1270848])

HSP 1 Score: 82.8037 bits (203), Expect = 1.564e-17
Identity = 55/181 (30.39%), Postives = 88/181 (48.62%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERG-----KDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSP 795
            +VI GS K GKT+I+SRFL   F  +Y PTIED   + +   G  Y +  +DT   + FPAM  + I     FILV S+ + +S   +  +  QI   +         ++  PL++  NK D    R + Q  I++ +   +     +   SAK N  ++ +F++L+       L  E+SP
Sbjct:   27 MVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDTKSCLKNKTKENVDVPLVICGNKGDRDFYREVEQREIEQLVG-DDPQRCAYFEISAKKNSSLDQMFRALFAMA---KLPSEMSP 203          
BLAST of GTP-binding protein vs. UniProt/SwissProt
Match: sp|Q94694|RAP1_PHYPO (Ras-related protein Rap-1 OS=Physarum polycephalum OX=5791 GN=RAP1 PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.087e-23
Identity = 58/169 (34.32%), Postives = 91/169 (53.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F+LV S+   ++ N L ++  QI   R KD     P+++V NK D  +QR+IS E  D+    R      F+  SAKN I +E IF  L  Q  R +
Sbjct:    8 IVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSIIAMSTFNDLPDLREQIL--RVKDCDDV-PMVLVGNKCDLAEQRVISTEQGDEL--ARKFGGCAFLEASAKNKINVEQIFYDLIRQINRKN 171          
BLAST of GTP-binding protein vs. UniProt/SwissProt
Match: sp|P18613|RAPA_DICDI (Ras-related protein rapA OS=Dictyostelium discoideum OX=44689 GN=rapA PE=1 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 2.081e-22
Identity = 56/169 (33.14%), Postives = 93/169 (55.03%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +  +  ++ +DT    +F AM ++Y+   Q F+LV S+  +++ N L ++  QI   R KD     P+++V NK D  DQR+IS E  ++    R   +  F+  SAKN + +E IF +L  Q  R +
Sbjct:    8 IVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDSNQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSIISNSTFNELPDLREQIL--RVKDCEDV-PMVLVGNKCDLHDQRVISTEQGEELA--RKFGDCYFLEASAKNKVNVEQIFYNLIRQINRKN 171          
BLAST of GTP-binding protein vs. UniProt/SwissProt
Match: sp|Q18246|RAP1_CAEEL (Ras-related protein Rap-1 OS=Caenorhabditis elegans OX=6239 GN=rap-1 PE=3 SV=1)

HSP 1 Score: 95.1301 bits (235), Expect = 7.527e-22
Identity = 58/202 (28.71%), Postives = 103/202 (50.99%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEE---KFINTSAKNNIGIENIFKSLWYQ---KYRHSLNRELSPKHDYFTLAQSLRRCSDAIII 855
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F+LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ ++      Q +N+  +    F+ TSAK  I +  +F  L  Q   +Y  S  R+           QS ++C   +I+
Sbjct:    6 IVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLMDLRDQILRVKDTD---EVPMILVGNKCDLEDERVVGKD------QGQNLARQFGSAFLETSAKAKINVSEVFYDLVRQINRRYPESGRRQ----------GQSNKQCCSCVIM 188          
BLAST of GTP-binding protein vs. UniProt/SwissProt
Match: sp|Q6TEN1|RAP1B_DANRE (Ras-related protein Rap-1b OS=Danio rerio OX=7955 GN=rap1b PE=2 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 4.811e-21
Identity = 53/169 (31.36%), Postives = 89/169 (52.66%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNSCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. UniProt/SwissProt
Match: sp|Q640R7|RAP1B_XENTR (Ras-related protein Rap-1b OS=Xenopus tropicalis OX=8364 GN=rap1b PE=2 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 5.486e-21
Identity = 53/169 (31.36%), Postives = 89/169 (52.66%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. TrEMBL
Match: A0A0R3WEQ5 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS9308 PE=4 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 5.334e-27
Identity = 69/183 (37.70%), Postives = 97/183 (53.01%), Query Frame = 1
Query:  259 VITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERG------KDFHIY---------SPLMVVANKIDC-LDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            V  VV  G+ K GKTSI+ RFL  SF   Y PT++D+ + +F+  G   +V+F+DT   Y+FPAM  + + KA AF++V +     SL        QI SER        D H Y         SPL+VV NK D  +    +S+  I +WL    +   +F+ TSAK +  I +IFK+LW Q
Sbjct:   35 VCRVVFLGAAKVGKTSIIRRFLNGSFEPKYTPTVDDIYSSKFLVRGCLANVEFMDTSGSYDFPAMIRLCVAKANAFVIVFAHDSMESLTTAGRYLEQIKSEREDYAPLLTDPHAYATSSLVETPSPLVVVCNKSDLPISMSKVSEGVIMEWLLKSGLKPSQFVYTSAKTDECIVDIFKALWLQ 217          
BLAST of GTP-binding protein vs. TrEMBL
Match: A0A564YGG6 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS6234 PE=4 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 1.080e-26
Identity = 68/186 (36.56%), Postives = 102/186 (54.84%), Query Frame = 1
Query:  253 RDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDF-------HIY---------SPLMVVANKIDC-LDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            + V  VV  G+ K GKTSI+ RFL  +F   Y PT++DV + +F+  G +  V+F+DT   Y+FPAM  + + KA AF++V +  +  SL        QI +ER +D+       H Y         SPL+VV NK D  +    +S+  I +WL    +   +F+ TSAK +  I++IFK+LW Q
Sbjct:   33 KSVCRVVFLGAAKVGKTSIIRRFLNGNFEPKYIPTVDDVYSSKFLVRGCQASVEFMDTSGSYDFPAMIRLCVAKADAFVIVFAHDNMESLTAASRYLEQIKAER-EDYAPLVTEPHAYDSSTLMATPSPLVVVCNKSDLPMPMSKVSEGVIMEWLLKSGLKPSQFVYTSAKTDECIQDIFKALWSQ 217          
BLAST of GTP-binding protein vs. TrEMBL
Match: A0A0R3S8A6 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS360 PE=4 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 1.090e-26
Identity = 68/186 (36.56%), Postives = 102/186 (54.84%), Query Frame = 1
Query:  253 RDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDF-------HIY---------SPLMVVANKIDC-LDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            + V  VV  G+ K GKTSI+ RFL  +F   Y PT++DV + +F+  G +  V+F+DT   Y+FPAM  + + KA AF++V +  +  SL        QI +ER +D+       H Y         SPL+VV NK D  +    +S+  I +WL    +   +F+ TSAK +  I++IFK+LW Q
Sbjct:   39 KSVCRVVFLGAAKVGKTSIIRRFLNGNFEPKYIPTVDDVYSSKFLVRGCQASVEFMDTSGSYDFPAMIRLCVAKADAFVIVFAHDNMESLTAASRYLEQIKAER-EDYAPLVTEPHAYDSSTLMATPSPLVVVCNKSDLPMPMSKVSEGVIMEWLLKSGLKPSQFVYTSAKTDECIQDIFKALWSQ 223          
BLAST of GTP-binding protein vs. TrEMBL
Match: U6JHJ4 (GTP-binding protein Rhes OS=Echinococcus granulosus OX=6210 GN=EGR_05448 PE=4 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 1.972e-26
Identity = 69/185 (37.30%), Postives = 96/185 (51.89%), Query Frame = 1
Query:  253 RDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERG------KDFHIY---------SPLMVVANKIDC-LDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            + V  VV  G+ K GKTSI+ RFL   F   Y PT++DV + +F+  G   +V+F+DT   Y+FPAM  + + KA AF++V +     SL        QI SER        D H Y         SPL+VV NK D       +S+  I +WL    +   +F+ TSAK +  I +IFK+LW Q
Sbjct:   33 KSVCRVVFLGAAKVGKTSIIRRFLNGCFEPKYTPTVDDVYSSKFLVRGCLANVEFMDTSGSYDFPAMIRLCVAKANAFVIVFAHDSMESLTTAGRYLEQIKSEREDYAPLVSDPHAYETSTLMATPSPLVVVCNKSDLPTSMSKVSEGVIMEWLLKSGLKPSQFVYTSAKTDECIVDIFKALWSQ 217          
BLAST of GTP-binding protein vs. TrEMBL
Match: A0A087VXI6 (Small GTPase Ras dva 3 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000073700 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 7.656e-26
Identity = 68/185 (36.76%), Postives = 95/185 (51.35%), Query Frame = 1
Query:  253 RDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERG------KDFHIY---------SPLMVVANKIDC-LDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            +    VV  G+ K GKTSI+ RFL   F   Y PT++DV + +F+  G   +V+F+DT   Y+FPAM  + + KA AF++V +     SL        QI SER        D H Y         SPL+VV NK D       +S+  I +WL    +   +F+ TSAK +  I +IFK+LW Q
Sbjct:   33 KSACRVVFLGAAKVGKTSIIRRFLNGCFEPKYTPTVDDVYSSKFLVRGCLANVEFMDTSGSYDFPAMIRLCVAKANAFVIVFAHDSMESLTTAGRYLEQIKSEREDYAPLVSDPHAYETSTLMATPSPLVVVCNKSDLPTSMSKVSEGVIMEWLLKSGLKPSQFVYTSAKTDECIVDIFKALWSQ 217          
BLAST of GTP-binding protein vs. Ensembl Cavefish
Match: rap1b (RAP1B, member of RAS oncogene family [Source:NCBI gene;Acc:103035254])

HSP 1 Score: 92.8189 bits (229), Expect = 5.456e-22
Identity = 53/169 (31.36%), Postives = 89/169 (52.66%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTD---DVPMILVGNKCDLEDERVVGKEQGQNLA--RQWNSCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Cavefish
Match: rap1aa (RAP1A, member of RAS oncogene family [Source:NCBI gene;Acc:103047011])

HSP 1 Score: 92.8189 bits (229), Expect = 5.533e-22
Identity = 55/169 (32.54%), Postives = 90/169 (53.25%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Cavefish
Match: rap1ab (ras-related protein Rap-1A [Source:NCBI gene;Acc:103022868])

HSP 1 Score: 92.4337 bits (228), Expect = 7.876e-22
Identity = 55/169 (32.54%), Postives = 91/169 (53.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I + +IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNL--ARQWNHCAFLESSAKSKINVLDIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Cavefish
Match: rasd4 (ras-related protein Rap-1b-like [Source:NCBI gene;Acc:103035404])

HSP 1 Score: 92.0485 bits (227), Expect = 2.108e-21
Identity = 56/180 (31.11%), Postives = 93/180 (51.67%), Query Frame = 1
Query:  262 ITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETI--DKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSP 795
            I +V  G+   GKT+++ RFL  SF   +  T+E++ ++++   G++  +  +DT   Y FPAM  + I    AF LV SV D  SL+ + ++  +I   +   F   +P++VV NK D L +R +S + +     L + N     F+  SAK N  +  +F+ L  Q    +L   LSP
Sbjct:   12 IRLVFMGAAGVGKTALIQRFLQDSFEPKHRRTVEELHSKEYEVGGVKVTINIMDTSGSYSFPAMRKLSIQNGDAFALVYSVDDPESLDAVKSLREEILEVKEDKF---TPIVVVGNKTDRLGERRVSADDVLATVELDWNNC----FLEASAKENNNVLEVFRELLQQ---ANLPSRLSP 181          
BLAST of GTP-binding protein vs. Ensembl Cavefish
Match: rap1aa (RAP1A, member of RAS oncogene family [Source:NCBI gene;Acc:103047011])

HSP 1 Score: 88.1965 bits (217), Expect = 3.209e-20
Identity = 50/154 (32.47%), Postives = 84/154 (54.55%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGI 729
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLESSAKSKINV 154          
BLAST of GTP-binding protein vs. Ensembl Sea Lamprey
Match: rasd3 (RASD family member 3 [Source:ZFIN;Acc:ZDB-GENE-060818-9])

HSP 1 Score: 79.7221 bits (195), Expect = 1.994e-17
Identity = 42/127 (33.07%), Postives = 65/127 (51.18%), Query Frame = 1
Query:  250 HRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHI----YSPLMVVANKID 618
             R  + +V  G+   GKTSI+ RFL  +F T Y PT+E++   ++   G +  ++ +DT   Y FPAM  +YI    AF LV S+ +  S       F ++   R +   I      P++V+ANK D
Sbjct:    7 ERTQVRLVFLGAAGVGKTSIIKRFLQGAFETRYRPTVEELYALEYEAGGSKIKLEVMDTSGSYRFPAMRKLYIRDGDAFALVFSLEEPQS-------FEEVRRLREEVLEIKEDKCPPIVVIANKAD 126          
BLAST of GTP-binding protein vs. Ensembl Sea Lamprey
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 76.6406 bits (187), Expect = 1.216e-16
Identity = 56/164 (34.15%), Postives = 86/164 (52.44%), Query Frame = 1
Query:  286 GKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFIT-NGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLW-YQKYRH 771
            G  GK+S++ RF+  +F  +Y PT+ED T RQ I+ +     +Q  DT   ++FPAM  + I +  AF+LV SVT   SL  L  ++  IA  +G    +  P+M+VANK D   + + + E   +   +R      F  TSAK +  +   F+ L   +K RH
Sbjct:   16 GGVGKSSLVLRFVRGTFREAYVPTVED-TYRQVISCDKSVCTLQITDTTGSHQFPAMQRLAISRGHAFLLVYSVTSRQSLEELRPIYDVIAQIKGDVSAV--PMMLVANKCDETAREVAAGEGETQAKAWRCA----FTETSAKMDYNVSEAFQELLTLEKRRH 172          
BLAST of GTP-binding protein vs. Ensembl Sea Lamprey
Match: DIRAS2 (DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323])

HSP 1 Score: 75.0998 bits (183), Expect = 3.736e-16
Identity = 50/162 (30.86%), Postives = 84/162 (51.85%), Query Frame = 1
Query:  298 KTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIE-YHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLN 780
            K+S++ RF+  +F  SY PT+ED T RQ I+       +Q  DT   ++FPAM  + I +  AF+LV S+    SL  L  ++  I S +G    +  P+M+V NK D   + + + E   +   +R      F+ TSAK +  +  +F+ L   + R +++
Sbjct:   20 KSSLVLRFVRGTFRESYIPTVED-TYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISRGHAFVLVYSIASRQSLEELRPIYEVICSLKGDTEAV--PIMLVGNKCDETTREVQTAEGEAQAKAWRCA----FMETSAKMDYNVRELFQELLNLEKRRNVS 174          
BLAST of GTP-binding protein vs. Ensembl Sea Lamprey
Match: RIT2 (Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HGNC:10017])

HSP 1 Score: 75.485 bits (184), Expect = 4.160e-16
Identity = 48/162 (29.63%), Postives = 77/162 (47.53%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYS-PLMVVANKIDCLDQRIISQETIDKWLQYRNINEE---KFINTSAKNNIGIENIF 741
            +V+ G G  GK+++  +F+   FP  ++PTIED    Q   +    H+  +DT    EF AM + Y+   + FI+  S+TD  S          I   R    H Y  P+++V NK D  + R +SQE      + R++  E   +F  TSA     ++ +F
Sbjct:   23 IVMLGPGGVGKSAMTMQFISHRFPEDHDPTIEDAYKTQVRIDDETAHLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFQEAAQFKQLIYQVR----HTYEVPVVLVGNKTDLGEIRQVSQE------EGRSLAREFSCQFFETSAALRQYVDEVF 174          
BLAST of GTP-binding protein vs. Ensembl Sea Lamprey
Match: ralba (v-ral simian leukemia viral oncogene homolog Ba (ras related) [Source:ZFIN;Acc:ZDB-GENE-040801-267])

HSP 1 Score: 68.5514 bits (166), Expect = 8.704e-14
Identity = 38/158 (24.05%), Postives = 74/158 (46.84%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIF 741
            V++ GSG  GK+++  +F++  F   Y PT  D   ++ + +G E  +  +DT    ++ A+ + Y    + F+ V S+ +  S         QI   +  D     P ++V NK D  ++R +S E      +   ++   ++ TSAK    ++ +F
Sbjct:   16 VIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSICEHESFAATLEFREQILRVKEDD---SVPFLLVGNKSDLEERRQVSSEEARARAEQWRVS---YVETSAKTRANVDKVF 167          
BLAST of GTP-binding protein vs. Ensembl Yeast
Match: RSR1 (GTP-binding protein of the Ras superfamily; required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases [Source:SGD;Acc:S000003384])

HSP 1 Score: 79.7221 bits (195), Expect = 1.829e-17
Identity = 50/174 (28.74%), Postives = 89/174 (51.15%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIIS-QETID---KWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSL 777
            +V+ G+G  GK+ +  +F+   +  +Y+PTIED   +    +   + ++ +DT  + +F AM  +YI     F+LV SVTD  SL  L  +  Q+   +  D     P++++ NK D +++R+IS +E I+   KW +        F  TSA     ++ +F  L  Q  R+ +
Sbjct:    6 LVVLGAGGVGKSCLTVQFVQGVYLDTYDPTIEDSYRKTIEIDNKVFDLEILDTAGIAQFTAMRELYIKSGMGFLLVYSVTDRQSLEELMELREQVLRIKDSD---RVPMVLIGNKADLINERVISVEEGIEVSSKWGRV------PFYETSALLRSNVDEVFVDLVRQIIRNEM 170          
BLAST of GTP-binding protein vs. Ensembl Yeast
Match: RAS1 (GTPase involved in G-protein signaling in adenylate cyclase activation; plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes; relative distribution to the nucleus increases upon DNA replication stress; RAS1 has a paralog, RAS2, that arose from the whole genome duplication [Source:SGD;Acc:S000005627])

HSP 1 Score: 76.2554 bits (186), Expect = 5.039e-16
Identity = 57/170 (33.53%), Postives = 90/170 (52.94%), Query Frame = 1
Query:  298 KTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWY------QKYRHSLNREL 789
            K+++  +F+   F   Y+PTIED   +Q + +     +  +DT    E+ AM   Y+   + F+LV SVT  NS + L + + QI  +R KD   Y P++VV NK+D  ++R +S E  D     + +N   F+ TSAK  I ++  F SL         KY +S+NR+L
Sbjct:   23 KSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMREQYMRTGEGFLLVYSVTSRNSFDELLSYYQQI--QRVKDSD-YIPVVVVGNKLDLENERQVSYE--DGLRLAKQLN-APFLETSAKQAINVDEAFYSLIRLVRDDGGKY-NSMNRQL 185          
BLAST of GTP-binding protein vs. Ensembl Yeast
Match: YPT6 (Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6 [Source:SGD;Acc:S000004252])

HSP 1 Score: 68.5514 bits (166), Expect = 6.036e-14
Identity = 48/173 (27.75%), Postives = 85/173 (49.13%), Query Frame = 1
Query:  235 KSMSTHRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIE-DVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSL 750
            KS++ ++    +V  G    GKTS+++RF++ +F   Y  TI  D  ++    +     +Q  DT     F ++   YI  ++  I+V  +T   S  Y+D     + +ERG +  I   L +V NK D  D+R IS E  +K  + + +  + F+ TS K    ++ +FK +
Sbjct:    6 KSLTKYK----IVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYIDKWIEDVKNERGDENVI---LCIVGNKSDLSDERQISTEEGEK--KAKLLGAKIFMETSTKAGYNVKALFKKI 169          
BLAST of GTP-binding protein vs. Ensembl Yeast
Match: RAS2 (GTP-binding protein; regulates nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes; RAS2 has a paralog, RAS1, that arose from the whole genome duplication [Source:SGD;Acc:S000005042])

HSP 1 Score: 66.6254 bits (161), Expect = 9.200e-13
Identity = 51/150 (34.00%), Postives = 78/150 (52.00%), Query Frame = 1
Query:  304 SILSRFLWQS-FPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSL 750
            S L+  L QS F   Y+PTIED   +Q + +     +  +DT    E+ AM   Y+   + F+LV S+T  +SL+ L   + QI   R KD   Y P++VV NK D  +++ +S +  D     + +N   F+ TSAK  I +E  F +L
Sbjct:   24 SALTIQLTQSHFVDEYDPTIEDSYRKQVVIDDEVSILDILDTAGQEEYSAMREQYMRNGEGFLLVYSITSKSSLDELMTYYQQIL--RVKDTD-YVPIVVVGNKSDLENEKQVSYQ--DGLNMAKQMN-APFLETSAKQAINVEEAFYTL 167          
BLAST of GTP-binding protein vs. Ensembl Yeast
Match: VPS21 (Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication [Source:SGD;Acc:S000005615])

HSP 1 Score: 56.225 bits (134), Expect = 8.174e-10
Identity = 49/175 (28.00%), Postives = 81/175 (46.29%), Query Frame = 1
Query:  241 MSTHRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGI---EYHVQFI--DTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLD---QRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIF 741
            M+T    I +V+ G    GK+SI+ RF+   F  +  PTI       F+T  +   E+ V+F   DT     F ++  +Y   AQA ++V  VT   S     +   ++  +  KD  I     +V NKID L    +R +++E  +K  + + +    F  TSAK    + ++F
Sbjct:    1 MNTSVTSIKLVLLGEAAVGKSSIVLRFVSNDFAENKEPTI----GAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIII----ALVGNKIDMLQEGGERKVAREEGEKLAEEKGL---LFFETSAKTGENVNDVF 164          
BLAST of GTP-binding protein vs. Ensembl Nematostella
Match: EDO39047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB93])

HSP 1 Score: 93.2041 bits (230), Expect = 1.330e-22
Identity = 53/173 (30.64%), Postives = 93/173 (53.76%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEE----KFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F+LV S+T  ++ N L ++  QI   +  D     P+++V NK D  D+R++ ++      Q +N+ ++     F+ TSAK  I +  IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTD---DVPMVLVGNKCDLEDERVVGKD------QGQNLAKQFANCTFLETSAKAKINVNEIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Nematostella
Match: EDO36578 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI58])

HSP 1 Score: 85.5001 bits (210), Expect = 6.569e-20
Identity = 62/174 (35.63%), Postives = 85/174 (48.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANK------------IDCLDQRIISQETID-KWLQYRNINEEKFINTSAKNNIGIENIFKSL 750
            +V FG+   GKTS++ RFL  +F   Y+PTIED   +    N   Y +Q IDT   YEFPAM  + I K  AF+LV S     S   L+   ++I  E GK+ H   P +VV NK             D    RI +Q  +  +W       +  +I+ SAK N  +E+IF  L
Sbjct:    1 IVFFGASSVGKTSLILRFLGYAFNDDYSPTIEDFFIKHVFFNNETYELQIIDTSGTYEFPAMRKVDIAKGDAFVLVYSQDHPESFTKLNRYRSEIL-EGGKNRH---PCIVVCNKNDLPLATHLGVLTDHRGLRISAQHLVQTEW-------QSLWIDCSAKENSQVEDIFLRL 163          
BLAST of GTP-binding protein vs. Ensembl Nematostella
Match: EDO27138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI58])

HSP 1 Score: 85.5001 bits (210), Expect = 6.569e-20
Identity = 62/174 (35.63%), Postives = 85/174 (48.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANK------------IDCLDQRIISQETID-KWLQYRNINEEKFINTSAKNNIGIENIFKSL 750
            +V FG+   GKTS++ RFL  +F   Y+PTIED   +    N   Y +Q IDT   YEFPAM  + I K  AF+LV S     S   L+   ++I  E GK+ H   P +VV NK             D    RI +Q  +  +W       +  +I+ SAK N  +E+IF  L
Sbjct:    1 IVFFGASSVGKTSLILRFLGYAFNDDYSPTIEDFFIKHVFFNNETYELQIIDTSGTYEFPAMRKVDIAKGDAFVLVYSQDHPESFTKLNRYRSEIL-EGGKNRH---PCIVVCNKNDLPLATHLGVLTDHRGLRISAQHLVQTEW-------QSLWIDCSAKENSQVEDIFLRL 163          
BLAST of GTP-binding protein vs. Ensembl Nematostella
Match: EDO33484 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS29])

HSP 1 Score: 83.5741 bits (205), Expect = 4.872e-19
Identity = 60/198 (30.30%), Postives = 93/198 (46.97%), Query Frame = 1
Query:  226 IRHKSMSTHRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQ--YRNINEEKFIN-----TSAKNNIGIENIFKSLWYQKYRHSLNRELSPK 798
            ++ K  S H     + +FG    GKTSI+ RF    F   Y PT+ED  ++    NG    +   D+   Y+FPAM  + I +A  FILV S+    S   L  +  ++  E+ K   I  P+++V NK D  +QR +S E + K +    R    E  +N     TSAK++  I ++F  +     +H   +E   K
Sbjct:    1 MKEKRNSLHE----IAVFGGAGVGKTSIVKRFYCGKFSEEYEPTVEDCYSKVLNKNGSIMVLNTTDSSGSYQFPAMREVAIKRASGFILVYSLDSKFSFEELKRLLYEVI-EKKKSADI--PVVLVGNKKDLEEQREVSSEQVVKEVMAFAREKGCEGKLNMRQVETSAKDDCNISDVFDEVVDMLDKHPNKQEKQKK 191          
BLAST of GTP-binding protein vs. Ensembl Nematostella
Match: EDO30327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T133])

HSP 1 Score: 83.5741 bits (205), Expect = 6.306e-19
Identity = 57/179 (31.84%), Postives = 87/179 (48.60%), Query Frame = 1
Query:  226 IRHKSMSTHRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQ--YRNINEEKFIN-----TSAKNNIGIENIF 741
            ++ K  S H     + +FG    GKTSI+ RF    F   Y PT+ED  ++    NG    +   D+   Y+FPAM  + I +A  FILV S+    S   L  +  ++  E+ K   I  P+++V NK D  +QR +S E + K +    R    E  +N     TSAK++  I ++F
Sbjct:    1 MKEKRNSLHE----IAVFGGAGVGKTSIVKRFYCGKFSEEYEPTVEDCYSKVLNKNGSIMVLNTTDSSGSYQFPAMREVAIKRASGFILVYSLDSKFSFEELKRLLYEVI-EKKKSADI--PVVLVGNKKDLEEQREVSSEQVVKEVMAFAREKGCEGKLNMRQVETSAKDDCNISDVF 172          
BLAST of GTP-binding protein vs. Ensembl Medaka
Match: rap1aa (ras-related protein O-Krev [Source:NCBI gene;Acc:101171247])

HSP 1 Score: 96.2857 bits (238), Expect = 3.491e-23
Identity = 60/183 (32.79%), Postives = 95/183 (51.91%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSPKHDYFTL 816
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ TSAK+ I +  IF  L  Q  R S   + + K    TL
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLETSAKSKINVNEIFYDLVRQINRKSPPEKKTKKKSGCTL 183          
BLAST of GTP-binding protein vs. Ensembl Medaka
Match: rap1ab (ras-related protein Rap-1A [Source:NCBI gene;Acc:101167529])

HSP 1 Score: 92.4337 bits (228), Expect = 8.316e-22
Identity = 55/169 (32.54%), Postives = 91/169 (53.85%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHS 774
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ +SAK+ I + +IF  L  Q  R +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNL--ARQWNNCAFLESSAKSKINVLDIFYDLVRQINRKT 169          
BLAST of GTP-binding protein vs. Ensembl Medaka
Match: ENSORLT00000000267.2 (ras-related protein Rap-2a [Source:NCBI gene;Acc:101163576])

HSP 1 Score: 92.4337 bits (228), Expect = 1.516e-21
Identity = 53/168 (31.55%), Postives = 91/168 (54.17%), Query Frame = 1
Query:  262 ITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKW--LQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            + +V  G+G  GKT+++ RFL  +F   +  T+E++  +++    ++  +  IDT   Y FPAM  + I    AF LV SV D +SL  +  +  +I  E  +D H  +P++V+ NKID  ++R++S   +     L + +I    F+ +SAK+NI +   F  L  Q
Sbjct:   11 VRLVFLGAGGVGKTALIHRFLQDTFDPKHRRTVEEIHRKEYEVGDVKVTINIIDTSGSYSFPAMRKLSIQTGDAFALVYSVDDPDSLETVKRLRDEII-ELKEDKH--APIVVIGNKIDRHNERLVSSRDVLAMVELDWDHI----FVESSAKDNINVLEAFMELLQQ 171          
BLAST of GTP-binding protein vs. Ensembl Medaka
Match: ENSORLT00000047032.1 (ras-related protein Rap-1b [Source:NCBI gene;Acc:101172864])

HSP 1 Score: 89.3521 bits (220), Expect = 1.229e-20
Identity = 54/164 (32.93%), Postives = 89/164 (54.27%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D   +R++++E+       R  N   F+ TSAK+ I +  IF  L  Q
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEVERVVAKESGIGL--ARQWNSCAFLETSAKSKINVNEIFYDLVRQ 164          
BLAST of GTP-binding protein vs. Ensembl Medaka
Match: rap1aa (ras-related protein O-Krev [Source:NCBI gene;Acc:101171247])

HSP 1 Score: 87.8113 bits (216), Expect = 4.976e-20
Identity = 51/154 (33.12%), Postives = 84/154 (54.55%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGI 729
            +V+ GSG  GK+++  +F+   F   Y+PTIED   +Q   +G +  ++ +DT    +F AM ++Y+   Q F LV S+T  ++ N L ++  QI   R KD     P+++V NK D  D+R++ +E        R  N   F+ TSAK+ I +
Sbjct:    6 LVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEIDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQIL--RVKDTEDV-PMILVGNKCDLEDERVVGKEQGQNLA--RQWNNCAFLETSAKSKINV 154          
BLAST of GTP-binding protein vs. Planmine SMEST
Match: SMESG000055098.1 (SMESG000055098.1)

HSP 1 Score: 543.888 bits (1400), Expect = 0.000e+0
Identity = 276/276 (100.00%), Postives = 276/276 (100.00%), Query Frame = 1
Query:  241 MSTHRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSPKHDYFTLAQSLRRCSDAIIIPSVKIERNRVSESLRVSSTKDSDLSTLGVAWLQLSLSKSTDSVAENNISSGIEXXXXXXXXXXXPVSCPIS 1068
            MSTHRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSPKHDYFTLAQSLRRCSDAIIIPSVKIERNRVSESLRVSSTKDSDLSTLGVAWLQLSLSKSTDSVAENNISSGIEKNKSSKSLKNSPVSCPIS
Sbjct:    1 MSTHRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSPKHDYFTLAQSLRRCSDAIIIPSVKIERNRVSESLRVSSTKDSDLSTLGVAWLQLSLSKSTDSVAENNISSGIEKNKSSKSLKNSPVSCPIS 276          
BLAST of GTP-binding protein vs. Planmine SMEST
Match: SMESG000049496.1 (SMESG000049496.1)

HSP 1 Score: 139.428 bits (350), Expect = 3.499e-38
Identity = 70/176 (39.77%), Postives = 108/176 (61.36%), Query Frame = 1
Query:  250 HRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKD------FHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            ++ + T+V FG GK+GK+ ++ +FL Q+F   Y  TIEDV NR+F  NG    +QFIDTG +Y FPAM  + I KA  F+ V S+TD  SL YL ++   I   +  +      F    PL+++ NK+D L++R + ++ ID+WL    +++E+F  TSAK   GI + F +L++Q
Sbjct:    8 NKHMKTIVFFGGGKTGKSCLIKQFLNQTFDKEYRSTIEDVYNRKFEINGRALDLQFIDTGGLYNFPAMRKLSIKKAVGFVFVFSLTDEESLYYLTDILNLINETKSSNNSSQILFTSSVPLIILGNKMDLLNKRCLYEDEIDRWLFESKLSKEQFFLTSAKEEDGIWDAFSNLYFQ 183          
BLAST of GTP-binding protein vs. Planmine SMEST
Match: SMESG000049496.1 (SMESG000049496.1)

HSP 1 Score: 139.043 bits (349), Expect = 4.148e-38
Identity = 70/171 (40.94%), Postives = 105/171 (61.40%), Query Frame = 1
Query:  265 TVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKD------FHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQ 759
            T+V FG GK+GK+ ++ +FL Q+F   Y  TIEDV NR+F  NG    +QFIDTG +Y FPAM  + I KA  F+ V S+TD  SL YL ++   I   +  +      F    PL+++ NK+D L++R + ++ ID+WL    +++E+F  TSAK   GI + F +L++Q
Sbjct:    3 TIVFFGGGKTGKSCLIKQFLNQTFDKEYRSTIEDVYNRKFEINGRALDLQFIDTGGLYNFPAMRKLSIKKAVGFVFVFSLTDEESLYYLTDILNLINETKSSNNSSQILFTSSVPLIILGNKMDLLNKRCLYEDEIDRWLFESKLSKEQFFLTSAKEEDGIWDAFSNLYFQ 173          
BLAST of GTP-binding protein vs. Planmine SMEST
Match: SMESG000015251.1 (SMESG000015251.1)

HSP 1 Score: 129.798 bits (325), Expect = 1.093e-34
Identity = 63/165 (38.18%), Postives = 97/165 (58.79%), Query Frame = 1
Query:  268 VVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQK 762
            +   G+GK GKTSI+ +FL  +F   Y PT+ED   +    NG + +VQFID+   Y FPAM  ++I KA AF+LV SVTD  S   LD++  +I   RG DF    P+++  NK D ++++ +  E  + W+   ++  +  I  SAK N  I ++F++LW Q+
Sbjct:    7 IAFLGTGKVGKTSIIRQFLQHTFIEKYTPTVEDTFTKVIDINGQQVNVQFIDSSGSYAFPAMRRLWIQKATAFVLVFSVTDKESFELLDSLLAEIKDVRGSDFQSNIPIVIAGNKND-IEKKCVEDEIAEDWVLNNDVPFDSLIFCSAKTNDSIHSLFQALWEQR 170          
BLAST of GTP-binding protein vs. Planmine SMEST
Match: SMESG000067334.1 (SMESG000067334.1)

HSP 1 Score: 132.109 bits (331), Expect = 7.914e-34
Identity = 68/185 (36.76%), Postives = 111/185 (60.00%), Query Frame = 1
Query:  256 DVITVVIF--GSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFITNGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNVFTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEEKFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSPKHD 804
            DV+  +I   G  + GKTS++ RF+ + F   Y PT+EDV  RQ+  N   Y ++F+DT   Y FPAM  + I KA AF+L++S+T SNS+  L  ++  +  E+ +      P++++ANK D L Q  IS+  I +W + RN+  +  I  S K+  G+ ++F+SLW QK + S + ++SP+ +
Sbjct:  262 DVVKEIILFLGDAQVGKTSLIKRFINEEFDEKYTPTVEDVYIRQYEINDWAYCIEFLDTSGRYTFPAMRRLNISKATAFVLMISMTQSNSIESLSQLWDDVLEEKDEGVFNKLPVVIIANKSDSLSQYQISENDIHQWAKQRNVPTDNVIVCSCKDESGVWDVFQSLWEQKVKTSPHLKISPRSN 446          
The following BLAST results are available for this feature:
BLAST of GTP-binding protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DIRAS26.002e-2133.71DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC... [more]
RAP1B9.011e-2130.77RAP1B, member of RAS oncogene family [Source:HGNC ... [more]
RAP1B9.011e-2130.77RAP1B, member of RAS oncogene family [Source:HGNC ... [more]
RAP1B9.011e-2130.77RAP1B, member of RAS oncogene family [Source:HGNC ... [more]
RAP1B9.011e-2130.77RAP1B, member of RAS oncogene family [Source:HGNC ... [more]
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BLAST of GTP-binding protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ssr-29.260e-2435.19Sperm-Specific family, class R [Source:UniProtKB/... [more]
rap-15.917e-2328.71Ras-related protein Rap-1 [Source:UniProtKB/Swiss... [more]
drn-17.064e-2136.05GTP-binding protein drn-1 [Source:UniProtKB/Swiss... [more]
D1081.43.177e-1734.68pep chromosome:WBcel235:I:8474886:8476282:-1 gene:... [more]
ras-29.476e-1733.13GTP binding protein; R-RAS related [Source:UniPro... [more]
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BLAST of GTP-binding protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG133756.262e-2333.92gene:FBgn0040370 transcript:FBtr0342963[more]
CG133758.827e-2333.92gene:FBgn0040370 transcript:FBtr0070103[more]
CG133758.827e-2333.92gene:FBgn0040370 transcript:FBtr0300326[more]
CG301583.953e-2232.12gene:FBgn0050158 transcript:FBtr0086165[more]
Rap12.611e-2130.49gene:FBgn0004636 transcript:FBtr0303154[more]
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BLAST of GTP-binding protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rap1b6.373e-2231.36RAP1B, member of RAS oncogene family [Source:NCBI ... [more]
rap1ab9.874e-2232.54RAP1A, member of RAS oncogene family b [Source:ZFI... [more]
rap1ab9.874e-2232.54RAP1A, member of RAS oncogene family b [Source:ZFI... [more]
rap1ab9.874e-2232.54RAP1A, member of RAS oncogene family b [Source:ZFI... [more]
rap1ab9.874e-2232.54RAP1A, member of RAS oncogene family b [Source:ZFI... [more]
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BLAST of GTP-binding protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rap1b1.036e-2131.36RAP1B, member of RAS oncogene family [Source:NCBI ... [more]
aldh1a32.193e-2132.54aldehyde dehydrogenase 1 family member A3 [Source:... [more]
pnp6.060e-2134.27purine nucleoside phosphorylase [Source:Xenbase;Ac... [more]
aldh1a36.209e-2031.65aldehyde dehydrogenase 1 family member A3 [Source:... [more]
aldh1a39.445e-2032.28aldehyde dehydrogenase 1 family member A3 [Source:... [more]
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BLAST of GTP-binding protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Diras24.887e-2133.71DIRAS family, GTP-binding RAS-like 2 [Source:MGI S... [more]
Rap1b6.187e-2130.77RAS related protein 1b [Source:MGI Symbol;Acc:MGI:... [more]
Rap1a2.600e-2031.21RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:... [more]
Rap1a7.387e-2031.48RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:... [more]
Rasd11.564e-1730.39RAS, dexamethasone-induced 1 [Source:MGI Symbol;Ac... [more]
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BLAST of GTP-binding protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q94694|RAP1_PHYPO2.087e-2334.32Ras-related protein Rap-1 OS=Physarum polycephalum... [more]
sp|P18613|RAPA_DICDI2.081e-2233.14Ras-related protein rapA OS=Dictyostelium discoide... [more]
sp|Q18246|RAP1_CAEEL7.527e-2228.71Ras-related protein Rap-1 OS=Caenorhabditis elegan... [more]
sp|Q6TEN1|RAP1B_DANRE4.811e-2131.36Ras-related protein Rap-1b OS=Danio rerio OX=7955 ... [more]
sp|Q640R7|RAP1B_XENTR5.486e-2131.36Ras-related protein Rap-1b OS=Xenopus tropicalis O... [more]
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BLAST of GTP-binding protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3WEQ55.334e-2737.70Uncharacterized protein OS=Taenia asiatica OX=6051... [more]
A0A564YGG61.080e-2636.56Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A0R3S8A61.090e-2636.56Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
U6JHJ41.972e-2637.30GTP-binding protein Rhes OS=Echinococcus granulosu... [more]
A0A087VXI67.656e-2636.76Small GTPase Ras dva 3 OS=Echinococcus multilocula... [more]
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BLAST of GTP-binding protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rap1b5.456e-2231.36RAP1B, member of RAS oncogene family [Source:NCBI ... [more]
rap1aa5.533e-2232.54RAP1A, member of RAS oncogene family [Source:NCBI ... [more]
rap1ab7.876e-2232.54ras-related protein Rap-1A [Source:NCBI gene;Acc:1... [more]
rasd42.108e-2131.11ras-related protein Rap-1b-like [Source:NCBI gene;... [more]
rap1aa3.209e-2032.47RAP1A, member of RAS oncogene family [Source:NCBI ... [more]
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BLAST of GTP-binding protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rasd31.994e-1733.07RASD family member 3 [Source:ZFIN;Acc:ZDB-GENE-060... [more]
DIRAS21.216e-1634.15DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC... [more]
DIRAS23.736e-1630.86DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC... [more]
RIT24.160e-1629.63Ras like without CAAX 2 [Source:HGNC Symbol;Acc:HG... [more]
ralba8.704e-1424.05v-ral simian leukemia viral oncogene homolog Ba (r... [more]
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BLAST of GTP-binding protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
RSR11.829e-1728.74GTP-binding protein of the Ras superfamily; requir... [more]
RAS15.039e-1633.53GTPase involved in G-protein signaling in adenylat... [more]
YPT66.036e-1427.75Rab family GTPase; required for endosome-to-Golgii... [more]
RAS29.200e-1334.00GTP-binding protein; regulates nitrogen starvation... [more]
VPS218.174e-1028.00Endosomal Rab family GTPase; required for endocyti... [more]
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BLAST of GTP-binding protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO390471.330e-2230.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365786.569e-2035.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO271386.569e-2035.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO334844.872e-1930.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO303276.306e-1931.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GTP-binding protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rap1aa3.491e-2332.79ras-related protein O-Krev [Source:NCBI gene;Acc:1... [more]
rap1ab8.316e-2232.54ras-related protein Rap-1A [Source:NCBI gene;Acc:1... [more]
ENSORLT00000000267.21.516e-2131.55ras-related protein Rap-2a [Source:NCBI gene;Acc:1... [more]
ENSORLT00000047032.11.229e-2032.93ras-related protein Rap-1b [Source:NCBI gene;Acc:1... [more]
rap1aa4.976e-2033.12ras-related protein O-Krev [Source:NCBI gene;Acc:1... [more]
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BLAST of GTP-binding protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000055098.10.000e+0100.00SMESG000055098.1[more]
SMESG000049496.13.499e-3839.77SMESG000049496.1[more]
SMESG000049496.14.148e-3840.94SMESG000049496.1[more]
SMESG000015251.11.093e-3438.18SMESG000015251.1[more]
SMESG000067334.17.914e-3436.76SMESG000067334.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30015015 ID=SMED30015015|Name=GTP-binding protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1146bp
CACAATGACAATATTCAAAGGAAATATGTAAATTGACCCGTAATCTACAA
TGGAAAAGGAATACATGATGTCTAGAAATTCTCTCAAGTGAACAATTTCC
CACCAATCGCATTCATTCATAGACAAATCACTCGCTGCCAGTGAATGTGA
AACAACATTTATTATATCAAAATAGTATTATCATTCTACGATTTATGCGA
ATCGAATATTCAAGGTGAACAATAAATAAGGCATAAATCCATGTCGACAC
ATAGAGATGTGATAACTGTAGTTATATTTGGAAGTGGTAAGTCTGGAAAG
ACTTCGATTCTTAGTAGATTCCTATGGCAGTCGTTTCCAACATCCTACAA
TCCTACAATTGAAGACGTGACTAACCGTCAGTTTATCACCAACGGTATTG
AATACCATGTGCAATTCATCGACACAGGAAGTGTTTATGAATTTCCTGCC
ATGTGGAACATTTACATTCACAAAGCCCAAGCTTTCATTCTTGTAATGTC
AGTGACAGACAGCAATTCTTTAAACTATTTAGACAATGTTTTTACACAAA
TCGCCAGCGAAAGAGGGAAGGATTTTCATATCTACAGTCCACTAATGGTT
GTTGCCAATAAAATAGATTGCTTGGATCAAAGAATAATTTCACAAGAAAC
AATTGATAAATGGCTTCAATACCGAAATATCAATGAAGAAAAGTTCATCA
ACACATCCGCAAAAAACAACATTGGAATTGAAAACATATTCAAAAGCCTC
TGGTATCAAAAATACAGGCATAGCTTGAACAGAGAATTGTCTCCCAAACA
TGACTATTTCACTTTGGCACAATCTTTGCGTCGTTGTAGCGACGCAATTA
TTATTCCGTCAGTAAAGATTGAGCGAAATCGAGTTTCCGAATCTTTAAGG
GTAAGCTCAACAAAAGACAGCGATTTATCCACACTGGGGGTGGCTTGGTT
GCAGTTATCGTTAAGTAAGTCTACTGATTCTGTTGCGGAAAACAATATAA
GTTCAGGAATTGAAAAAAATAAGAGCTCAAAATCTTTGAAAAATTCCCCG
GTTTCGTGTCCGATTTCGTGATTTATTTATAATATACATCCAGTATAACT
ATGAAGCAAACTTGCAATTTTATGATATTAAAAGTCTAAGACTTTA
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protein sequence of SMED30015015-orf-1

>SMED30015015-orf-1 ID=SMED30015015-orf-1|Name=SMED30015015-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=277bp
MSTHRDVITVVIFGSGKSGKTSILSRFLWQSFPTSYNPTIEDVTNRQFIT
NGIEYHVQFIDTGSVYEFPAMWNIYIHKAQAFILVMSVTDSNSLNYLDNV
FTQIASERGKDFHIYSPLMVVANKIDCLDQRIISQETIDKWLQYRNINEE
KFINTSAKNNIGIENIFKSLWYQKYRHSLNRELSPKHDYFTLAQSLRRCS
DAIIIPSVKIERNRVSESLRVSSTKDSDLSTLGVAWLQLSLSKSTDSVAE
NNISSGIEKNKSSKSLKNSPVSCPIS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003924GTPase activity
GO:0005525GTP binding
GO:0000166nucleotide binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR020849Small_GTPase_Ras-type
IPR001806Small_GTPase
IPR027417P-loop_NTPase
Vocabulary: biological process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO:0007165signal transduction
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
GO:0005886plasma membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 31..47
score: 29.41
coord: 114..127
score: 31.85
coord: 152..174
score: 29.87
coord: 8..29
score: 32.67
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 8..177
e-value: 3.8E-8
score: -8.0
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 1..177
e-value: 3.0E-18
score: 76.6
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 10..173
e-value: 2.0E-4
score: -60.5
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 2..194
e-value: 2.5E-40
score: 139.8
NoneNo IPR availablePANTHERPTHR24070:SF290RAS-DVA-2 SMALL GTPASE-RELATEDcoord: 8..202
NoneNo IPR availablePROSITEPS51419RABcoord: 1..230
score: 14.896
IPR001806Small GTPasePFAMPF00071Rascoord: 10..171
e-value: 3.4E-28
score: 98.3
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 8..168
e-value: 3.5E-19
score: 67.1
IPR020849Small GTPase superfamily, Ras-typePANTHERPTHR24070FAMILY NOT NAMEDcoord: 8..202
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 5..187