PKD2L-1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014978 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of PKD2L-1 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012]) HSP 1 Score: 184.882 bits (468), Expect = 3.004e-86 Identity = 101/256 (39.45%), Postives = 155/256 (60.55%), Query Frame = 3 Query: 180 EDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 + + + I TTL+EL +Y +FL L I+ FGM MY+L ++++LF++ V +F S+ S DFW F +GPLL GLYW+SWYNN + + + IY+EN L+G+ R+RQ++V + +C + + FQ ++ CY Y++ E FGLQ +T W Y+ +N S G + Y GGY L + + +L N WI RGTR + +DF++YNAN+NLFC+I+L+AEFPA GG++ + F +V Sbjct: 15 HKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYS-TSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSV 269 HSP 2 Score: 155.992 bits (393), Expect = 3.004e-86 Identity = 139/381 (36.48%), Postives = 223/381 (58.53%), Query Frame = 2 Query: 932 NC*ITEILFXXXXXXXXXXXXXXXXXSYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNEL-INQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENM 2071 +C IT +F+ +T +E+ +IK K +YFKS+WN L+++++ + F+ + FN Y V + +L LL + ++ +F +L+ + +N ++AIT+F AW+KIFK+ISFNKTM+QLSSTL RC KD+ GFA+MFFIIFFA+AQLG+L+FG+++ F SIF +RI+LGDF F A+ I GP+YF+ ++FFV FVL NMFLAIINDTYSE+K + I ++ +FE+G K+ + + + L+ A + D G D E + +GF D N + +A + + + +LE K + EI + + E ++ F++ V E+E ++ + LK+N V++ + + Sbjct: 284 SCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNV--------LEKFRLKKAQKDEDKKTKGSGDLAE---QARREGF--------------DENEIQNAEQMKKWKERLE--KKYYSMEIQDDYQPVTQEEFRELFLYAV-------------ELEKELHYINLKLNQVVRKVSAL 624
BLAST of PKD2L-1 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012]) HSP 1 Score: 185.267 bits (469), Expect = 1.116e-85 Identity = 101/256 (39.45%), Postives = 155/256 (60.55%), Query Frame = 3 Query: 180 EDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 + + + I TTL+EL +Y +FL L I+ FGM MY+L ++++LF++ V +F S+ S DFW F +GPLL GLYW+SWYNN + + + IY+EN L+G+ R+RQ++V + +C + + FQ ++ CY Y++ E FGLQ +T W Y+ +N S G + Y GGY L + + +L N WI RGTR + +DF++YNAN+NLFC+I+L+AEFPA GG++ + F +V Sbjct: 15 HKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYS-TSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSV 269 HSP 2 Score: 153.68 bits (387), Expect = 1.116e-85 Identity = 114/234 (48.72%), Postives = 169/234 (72.22%), Query Frame = 2 Query: 932 NC*ITEILFXXXXXXXXXXXXXXXXXSYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNEL-INQKNEFEIGDYFKE 1630 +C IT +F+ +T +E+ +IK K +YFKS+WN L+++++ + F+ + FN Y V + +L LL + ++ +F +L+ + +N ++AIT+F AW+KIFK+ISFNKTM+QLSSTL RC KD+ GFA+MFFIIFFA+AQLG+L+FG+++ F SIF +RI+LGDF F A+ I GP+YF+ ++FFV FVL NMFLAIINDTYSE+K + I ++ +FE+G K+ Sbjct: 284 SCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQ 517
BLAST of PKD2L-1 vs. Ensembl Human
Match: PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9011]) HSP 1 Score: 259.61 bits (662), Expect = 1.819e-74 Identity = 127/268 (47.39%), Postives = 177/268 (66.04%), Query Frame = 3 Query: 135 RFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G+R +W T TE+ NR LYI+TTLREL +YIVFL + ++ +GMT+ + Y+ T +++ LF++ + SF +++S ADFW FAQGPLL+ LYW WYNN ++ +FIY+EN L+G+ RLRQ++V + SC++ +F++ I CY YS E PFG N TAWTY Q LG G +++Y GGGYY+DLP + + L L LW+DRGTR V +DF+VYNANINLFCV++L+ EFPA GG IP + +TV Sbjct: 72 HICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTV 339 HSP 2 Score: 227.639 bits (579), Expect = 5.104e-63 Identity = 160/363 (44.08%), Postives = 235/363 (64.74%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEI---ESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHG------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMD 2074 Y S+WNILD+VVI +S + + F+I+RT+ V ++ LL N + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+KD+ GFAVMFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF + NA+ I GP YF+ YVFFV FVL NMFLAIINDTYSE+K EL QK+E ++ D K+ L +L L+K+++ +Q L + + F+++ ++E G +EI + F+++D DGNR+LD EQ +M+ LE ++ A+N EI I +S K+ VS +E+ L R+ ++E V+ +V +I+ V L+ ++ Sbjct: 381 YLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQE----IQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLE 739
BLAST of PKD2L-1 vs. Ensembl Human
Match: PKD2 (polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009]) HSP 1 Score: 227.639 bits (579), Expect = 2.706e-62 Identity = 170/432 (39.35%), Postives = 264/432 (61.11%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHG-------------------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSE--EERKVKIGNMVQEELIKLNQDAVLTQ 2227 YF+S WN LDVV++ +S + I NIYRT V+ +L+ L + N PNF++L+Y+Q FN + A+TVF W+K+FK+I+FN+TM+QLS+T+ RC+KDL GFA+MFFIIF A+AQL YL+FGT++ F IFT +RIILGD F + A+ + GP+YF +VFF+ F+L NMFLAIINDTYSE+K++L QK E E+ D ++ L KL LKK+ +D + +L G ++FDE + ++ KG EIE++F++YD DG++ L +E +M++ LE ++ ++ + S +P S ++F VS +E+Q L R++ ME+ I ++V KI+ V+ LE M+ +K KRR+ + ++L ++ E L E + ++ +V+EEL + D +Q Sbjct: 502 YFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQ-FLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLD----LDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQ 924 HSP 2 Score: 225.713 bits (574), Expect = 1.285e-61 Identity = 114/271 (42.07%), Postives = 171/271 (63.10%), Query Frame = 3 Query: 132 NRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGS--FNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 R G+R +W T+ E+ NR Y+++ LREL Y++FL +L I+ +GM + +Y+ T +++ LF++ V+ T F +++S DFW F +G LL+GLYW +N + +FI++EN L+G+ R+RQ+RV + SC I + + IK CY YS E PFG +N TAW YT + +L G I+TY G GYY+DL + + + +L N+W+DRGTRA +DF+VYNANINLFCV++L+ EFPA GGVIP + F+ + Sbjct: 191 ERLVRGLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSN-QTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPL 460
BLAST of PKD2L-1 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012]) HSP 1 Score: 186.037 bits (471), Expect = 9.320e-53 Identity = 101/256 (39.45%), Postives = 155/256 (60.55%), Query Frame = 3 Query: 180 EDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 + + + I TTL+EL +Y +FL L I+ FGM MY+L ++++LF++ V +F S+ S DFW F +GPLL GLYW+SWYNN + + + IY+EN L+G+ R+RQ++V + +C + + FQ ++ CY Y++ E FGLQ +T W Y+ +N S G + Y GGY L + + +L N WI RGTR + +DF++YNAN+NLFC+I+L+AEFPA GG++ + F +V Sbjct: 15 HKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYS-TSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSV 269 HSP 2 Score: 43.1282 bits (100), Expect = 9.320e-53 Identity = 38/121 (31.40%), Postives = 75/121 (61.98%), Query Frame = 2 Query: 932 NC*ITEILFXXXXXXXXXXXXXXXXXSYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSS--TLGR 1288 +C IT +F+ +T +E+ +IK K +YFKS+WN L+++++ + F+ + FN Y V + +L LL + ++ +F +L+ + +N ++AIT+F AW+K N T +++ + ++GR Sbjct: 284 SCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKNMFLAIINDTYSEVKADYSIGR 404
BLAST of PKD2L-1 vs. Ensembl Celegans
Match: pkd-2 (Polycystin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9U1S7]) HSP 1 Score: 147.132 bits (370), Expect = 1.874e-36 Identity = 87/227 (38.33%), Postives = 133/227 (58.59%), Query Frame = 3 Query: 240 YIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQ-VNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLP-SDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVI 914 Y VFL +L+ +AF + Y+ + ++++LFV + +F S S + W + L+ G+YW N+ + + N IY+EN+L+G R+R ++V++ SC + FQ+ IK C+ Y ++E G + A+ Y L +L G+I++YGGGG+ LP + A S + L N WIDRG+RA+IVDF +YNANINLFCV+KL+ E PA GGVI Sbjct: 80 YAVFLIVLVYVAFAQNSIQSYYYSKVMSDLFVASTGASGAPAFGSCTSMDNIWDWLSQVLIPGIYWTETSNSTDNE----NMIYYENRLLGEPRIRMLKVTNDSCTVMKSFQREIKECFANYEEKLEDKTMVGDGSVDAFIYATAKELENLKTVGTIASYGGGGFVQRLPVAGSTEAQSAIATLKANRWIDRGSRAIIVDFALYNANINLFCVVKLLFELPASGGVI 302 HSP 2 Score: 133.65 bits (335), Expect = 4.189e-32 Identity = 121/357 (33.89%), Postives = 196/357 (54.90%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMD---FDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMD 2074 Y WN++DVV++G S II ++ RT + S++ N + FD ++ + ++ + A VF+AWVK+FK+IS NKTM+QLSSTL R +KD+ GFAVMF + FFAFAQ GYL FGT++ + L+ S F L R+ILGDF F + + FGP +F+ YVFFV F+L NMFLAIIND+Y E+K EL +K+ I D+F + + LT D + ++++K + G+ +I F+R++ + + E+ V +I E + + +E K+ ++ + +Y +LN R+++M+ + ++V +I V L+ ++ Sbjct: 352 YLTQFWNLVDVVLLGFSVATIILSVNRTKTGVNRVNSVIENGLTNAPFDDVTSSENSYLNIKACVVFVAWVKVFKFISVNKTMSQLSSTLTRSAKDIGGFAVMFAVFFFAFAQFGYLCFGTQIADYSNLYNSAFALLRLILGDFNFSALESCNRFFGPAFFIAYVFFVSFILLNMFLAIINDSYVEVKAELARKKDGEGILDWFMNKVR------------------GLTKRGKRPDAPGEDATYEDYKLMLYRAGYAEKDINEAFTRFN--------------VTSMTEHVPEKVAEDIADEVARM--TEQKRNYME--NHRDYANLNRRVDQMQESVFSIVDRIEGVNATLQTIE 672
BLAST of PKD2L-1 vs. Ensembl Celegans
Match: lov-1 (Location of vulva defective 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09624]) HSP 1 Score: 77.411 bits (189), Expect = 3.482e-14 Identity = 76/293 (25.94%), Postives = 135/293 (46.08%), Query Frame = 3 Query: 99 NDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYW----LTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKL---IGLARLRQVRVSDKS-CIIANEFQKIIKRCYVTYSTQIESTEPF------------GLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIP 917 N K++ G ++ + + TE+ K R+ + T+R++ + L I++++ + YW ++ +LN +N + +F S+ + DFW +A+ L L SWY+ + + Y +K+ +G+ +RQVR + C + +FQ I C +++ E + G S +TY L + + G + +Y GGGY + + Q +L N L + WID TRAVI++F+ YNA IN F V++L+ E P G +P Sbjct: 2640 NPYGKIEKGLGTEIAD----VTKLRDTENRKM-RDEQLFITIRDMLCFFASLYIMVMLTYYCKDRHGYWYQLEMSTILN---INQKNYGDNTFMSIQHADDFWDWARESLATAL-LASWYDG---NPAYGMRAYMNDKVSRSMGIGTIRQVRTKKSAECTMFKQFQGYINDCGEELTSKNEEKTLYMQAGWTELESENGTDASDEYTYKTSEELSTETVSGLLYSYSGGGYTISMSGTQAEIITLFNKLDSERWIDDHTRAVIIEFSAYNAQINYFSVVQLLVEIPKSGIYLP 2920
BLAST of PKD2L-1 vs. Ensembl Fly
Match: Pkd2 (gene:FBgn0041195 transcript:FBtr0080365) HSP 1 Score: 131.724 bits (330), Expect = 4.261e-31 Identity = 91/211 (43.13%), Postives = 136/211 (64.45%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMM 1645 YF S+ NILD ++ ++ +++NI+ + V + L + +D + + D L ++ + ++AI FL W+KIFK+ISFNKT+ Q ++TL RCSKDLAGF++MF I+F A+AQLG LLFGTK FR SI T+ R+ILGDF + A+ + GP+YFL Y+ V F+L NMFLAII +TY+ +K E+ ++ +G Y + M Sbjct: 618 YFCSMLNILDCAILLGCYLALVYNIWHSFKVMS-LTARAHSDVTYQSLDVLCFWNIIYVDMMAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDFRNFITSILTMIRMILGDFQYNLIEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETYNTVKGEITQGRS--HLGSYIYRKLSGM 825 HSP 2 Score: 92.8189 bits (229), Expect = 5.404e-19 Identity = 59/168 (35.12%), Postives = 90/168 (53.57%), Query Frame = 3 Query: 435 NSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 +S N++ E +EN L+G RLRQ+RV +SC + + F + CY YS+ E +P + +L S PI ++ Y GGY V+L D+ ++N+L + W+DRG+R +V+F ++N N ++F IKLIAE P GGVIP +TV Sbjct: 412 DSIQANMSFHHLEGRVFLYENLLLGPPRLRQIRVRKESCYVNDAFIRYFNTCYAAYSSGAEDRKPM----HKGSPFRTMHDLDSTPIWTVLAFYRTGGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIPPTGGVIPQAHLQTV 575
BLAST of PKD2L-1 vs. Ensembl Zebrafish
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558]) HSP 1 Score: 236.498 bits (602), Expect = 2.751e-122 Identity = 158/353 (44.76%), Postives = 242/353 (68.56%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIIS-EQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLE 2065 S+F S+WNILD+VVI ++ + I+F+ +RT+ V +L +LL + + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQL+STL RC+ D+ GFA+MFFI+FFA+AQLGYLLFGT++ F + IFT +RIILGDF + A+ + GP+YF YVFFV FVL NMFLAIINDTYSE+K+EL +QK+EF+I D K+ KL LKK+K+ +Q AL + + ++F +++ A++E G EI + FS++D DGN+ LD EQ M+ +LE ++ A++ E+ E S P E + T V ++YQ L ++ ++EN ++ ++ K++ V++ + Sbjct: 372 SHFTSIWNILDIVVILLAVVAIVFSAFRTIKVDGLLGNLLKQPDIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLTSTLARCALDIFGFAIMFFIVFFAYAQLGYLLFGTEVETFSTFNKCIFTQFRIILGDFDYDAIDRANRVLGPIYFFSYVFFVFFVLLNMFLAIINDTYSEVKSELASQKDEFQIADLIKQSYAKTFMKLKLKKEKISDVQKALDSGASE----LEFKDFRNALKEMGHSDREISAAFSKFDQDGNQTLDKQEQENMKQELEEKRDALSAELRDLENSVEPAEEHRNT----VPPEDYQRLVHKVSQLENSVSAIMSKLDFVMEKMR 716 HSP 2 Score: 224.172 bits (570), Expect = 2.751e-122 Identity = 117/274 (42.70%), Postives = 170/274 (62.04%), Query Frame = 3 Query: 117 KYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 K G + F ++ +W T +D K N L ++ L+EL IYIVFL L ++ +GMT+ Y+ T + +LFVN +N SF+S+ D WT+ +GPLL+ LYW WYN+ ++ +FIY+EN L+G+ R+RQ++V SC + +F+K I C+ Y+ + E FGL N TAW Y + + G ++TY G G+Y DL + + + +LL +L NLW+DRGTR + +DFT YNANINLFCVI+L+ EFPA GG IP Y +TV Sbjct: 58 KSGCCSFFFRAIKGLWGTALRKDTKENPELNVKANLKELLIYIVFLVDLCLLTYGMTSSATYYYTKAMTDLFVNLPGSNGMSFSSIGCMNDVWTYMEGPLLDNLYWTKWYNDEPLENGNQSFIYYENLLLGVPRVRQLKVKQNSCKVPTDFKKEISDCFDVYNIKKEDDGAFGLINGTAWQYHSEKEIKGSSHWGLLTTYSGAGFYQDLTTTRDESAALLEDLRENLWLDRGTRVLFIDFTAYNANINLFCVIRLVVEFPATGGAIPSYQIRTV 331
BLAST of PKD2L-1 vs. Ensembl Zebrafish
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387]) HSP 1 Score: 232.261 bits (591), Expect = 2.640e-64 Identity = 174/432 (40.28%), Postives = 261/432 (60.42%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHG-------------------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLS--EEERKVKIGNMVQEELIKLNQDAVLTQ 2227 YFKS+WN LDV+++ +S II NI RT AV L LL N + +PNF+ L+ Q FN L AI VFL+WVK+FK+I+FNKTM QLS+T+ RC+KDL GFA+MFFI+F A+AQL YL+FGT++ F IFT +RIILGDF F + AD + GP+YF +VFF+ +L NMFLAIINDTYSE+K ++ Q++E EI D K+ + KL LKK ++ + ++L A G + FDE + ++ KG EIE++F++YD DG++ L +E +M++ LE ++ ++ E S +P S ++F VS +E+Q L R++ ME+ I ++V KI+ V+ LE M+ +K KRR + +IL + E + E ++ ++ +V++EL + D ++Q Sbjct: 438 YFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQA----AGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDL----EHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILDGVMEDERMGRDPELQREQMDRLVRDELERWESDDTMSQ 861 HSP 2 Score: 228.794 bits (582), Expect = 4.639e-63 Identity = 116/271 (42.80%), Postives = 179/271 (66.05%), Query Frame = 3 Query: 132 NRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNN--TGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 R MR +W T+ + +NR +Y++T LRE+ YI+FL L II +GM + MY+ T +++ LF++ +++ +F S+++ DFW F +GP LNG+YW WYNN ++ +++ + IY+EN L+G+ RLRQ+RV ++SC + + + + CY YS E PFG +N TAW + +++LG G +STYGGGGYY DL + + + L L NNLW+DRGTRAV +DF++YN N+NLFC+++L+ EFPA GG +P + F+TV Sbjct: 127 KRILEKMRVLWDTRLLGESNSNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSGEPTNFKSLSTMEDFWKFTEGPFLNGMYWELWYNNKSLPENQ-SLIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGPKNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTV 396
BLAST of PKD2L-1 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89]) HSP 1 Score: 117.857 bits (294), Expect = 1.833e-26 Identity = 100/304 (32.89%), Postives = 149/304 (49.01%), Query Frame = 3 Query: 45 VEYDAYDEISHADSVSFDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQ-----TTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQ-NST-----------AWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVG 905 V+ D Y ++S ++S +D + V+ + S + DI+ RN I+ +RE+ IY+ FL +L+++A+G Y+LT+ + F G + + D + +A LL LY Y D + +KL+G AR+RQVRV +C IAN Q ++ C+ YS + E + N T W Y Q L + P+ G ++ Y GGG+ VDL DQ +A LL LF+N W+D TRAV V+FTVYNAN+NLFC++ LI E VG Sbjct: 1917 VDQDEYGDVSIDGTLSNTDDPDAVRIAR----RDSTCSFYKPPPPTDIEKMRNNMIKEQKVFALIREILIYVGFLWMLLLVAYGQRDPNAYYLTHHIRQSFSTG-------ISETLNHKDIFIWANSSLLRNLYGQ--YPGFITDGN--------SKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVG 2199 HSP 2 Score: 64.3142 bits (155), Expect = 6.747e-10 Identity = 51/187 (27.27%), Postives = 101/187 (54.01%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSE 1570 +YFKS WN+L++ +I +S+ + + RT+ +E N + +F+ + YL+A V LA +K++ + N + ++STL R D++GF V+ I+F A++ L++G +L +R L + T+ + LG F + + L+ + + G + F+ FV+ N+F+++I ++E Sbjct: 2251 AYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVILVAFNE 2437
BLAST of PKD2L-1 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89]) HSP 1 Score: 114.39 bits (285), Expect = 1.921e-25 Identity = 93/267 (34.83%), Postives = 133/267 (49.81%), Query Frame = 3 Query: 156 SIWATKQTEDIKANRNLYIQ-----TTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQ-NST-----------AWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVG 905 S + DI+ RN I+ +RE+ IY+ FL +L+++A+G Y+LT+ + F G + + D + +A LL LY Y D + +KL+G AR+RQVRV +C IAN Q ++ C+ YS + E + N T W Y Q L + P+ G ++ Y GGG+ VDL DQ +A LL LF+N W+D TRAV V+FTVYNAN+NLFC++ LI E VG Sbjct: 590 SFYKPPPPTDIEKMRNNMIKEQKVFALIREILIYVGFLWMLLLVAYGQRDPNAYYLTHHIRQSFSTG-------ISETLNHKDIFIWANSSLLRNLYGQ--YPGFITDGN--------SKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVG 839 HSP 2 Score: 59.3066 bits (142), Expect = 1.847e-8 Identity = 51/187 (27.27%), Postives = 101/187 (54.01%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSE 1570 +YFKS WN+L++ +I +S+ + + RT+ +E N + +F+ + YL+A V LA +K++ + N + ++STL R D++GF V+ I+F A++ L++G +L +R L + T+ + LG F + + L+ + + G + F+ FV+ N+F+++I ++E Sbjct: 891 AYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVILVAFNE 1077
BLAST of PKD2L-1 vs. Ensembl Zebrafish
Match: pkd1l2b (polycystic kidney disease 1 like 2b [Source:ZFIN;Acc:ZDB-GENE-141222-87]) HSP 1 Score: 106.301 bits (264), Expect = 5.567e-23 Identity = 85/254 (33.46%), Postives = 132/254 (51.97%), Query Frame = 3 Query: 213 QTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGL------------QNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 Q + E+ I++ FL++L+++A+G ++LT + F + G +SM ++ D + +A LL L+ Y D + +KL+G AR+RQVRV +C +A + +C YS E +G + TAW Y Q+ L +LP+ G + Y GGGY +DL D+ +A L LFN+ W+D TRAV V+FTVYNAN++LFC++ LI E AVG + F++V Sbjct: 517 QALVMEVLIFLGFLSMLLLVAYGQQDPNAFYLTQHIQQSF------SKGISDSMKTN-DVFVWANTVLLKNLFGQ--YPGFITDGN--------SKLVGNARIRQVRVKKDTCKVAKVMLHTVSQCNTPYSWGNEDMMSYGPGWEEFNSVNGSEEGITAWQYQSQSTLKALPVWGLTALYRGGGYVMDLGPDKQNATMKLQYLFNSTWLDEYTRAVFVEFTVYNANVDLFCIVTLILESSAVGA----FQFRSV 749 HSP 2 Score: 53.9138 bits (128), Expect = 7.565e-7 Identity = 47/181 (25.97%), Postives = 96/181 (53.04%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAII 1552 +YF++ WN+LD+ +I +S+ + I +TV ++ + NQ P+F + T Y++A V L VK++ + + + ++S+L R D++ V+ FII A++ L+FG +L +R L + ++ + +G F + + +N++ G + V FV+ ++F++II Sbjct: 794 AYFRNKWNLLDMAIIILSWSSLSLFIQKTVQGNIDIQYYQKHKNQFPSFHDTAAVDATLRYVMAFLVLLGCVKLWHLLRLSPKLYVIASSLQRAWDDMSTLTVVIFIILLAYSLACNLIFGWELYTYRTLPDAFTAIFSLQIGIFNYDEVMNSNPALGAVIISSCVLIATFVVLSLFISII 974
BLAST of PKD2L-1 vs. Ensembl Xenopus
Match: PKD2L1 (polycystic kidney disease 2-like 1 [Source:NCBI gene;Acc:100495064]) HSP 1 Score: 248.054 bits (632), Expect = 1.468e-72 Identity = 125/264 (47.35%), Postives = 182/264 (68.94%), Query Frame = 3 Query: 147 GMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G+R +W T TE+ NR LYI+TTLREL +YIVFL + ++ +GMT+ Y+ TN+++ LF++ Q ++ +F ++++ DFW++ QGP+L+GLYW WYNN+++ + + IY+EN L+G+ R+RQ++V + SC++ +F+ I C+ YS E T FGL N TAWTY + LG G I+TY GGGYY+DL + + L L +NLW+DRGTRAV VDF+VYNANINLFCV++L+ EFPA GG IP + +TV Sbjct: 6 GIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSTNTYYYTNVMSKLFLDTQSDSGVTFKAISNMDDFWSYLQGPMLDGLYWTKWYNNVSLTDNTNSLIYYENLLLGVPRMRQLKVKNNSCMVYKDFKDEIVGCFDVYSKDKEDTSQFGLINGTAWTYYTEEELGGSSYWGKITTYSGGGYYIDLELTKRDSLRQLQTLKSNLWLDRGTRAVFVDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTV 269 HSP 2 Score: 186.422 bits (472), Expect = 3.515e-50 Identity = 120/206 (58.25%), Postives = 158/206 (76.70%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKE 1630 YF S+WNILDV+VI +S + I F+I+RT+ V ++ +LL N + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+KD+ GFA+MFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF + NA+ + GP+YF+ YVFFV FVL NMFLAIINDTYSE+K EL NQKNE + D K+ Sbjct: 311 YFTSIWNILDVIVILLSLVAIGFHIFRTMEVNRLMGTLLKNPTIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYDAIDNANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELSNQKNELQFSDILKQ 516
BLAST of PKD2L-1 vs. Ensembl Xenopus
Match: PKD2L1 (polycystic kidney disease 2-like 1 [Source:NCBI gene;Acc:100495064]) HSP 1 Score: 249.595 bits (636), Expect = 1.842e-72 Identity = 125/264 (47.35%), Postives = 182/264 (68.94%), Query Frame = 3 Query: 147 GMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G+R +W T TE+ NR LYI+TTLREL +YIVFL + ++ +GMT+ Y+ TN+++ LF++ Q ++ +F ++++ DFW++ QGP+L+GLYW WYNN+++ + + IY+EN L+G+ R+RQ++V + SC++ +F+ I C+ YS E T FGL N TAWTY + LG G I+TY GGGYY+DL + + L L +NLW+DRGTRAV VDF+VYNANINLFCV++L+ EFPA GG IP + +TV Sbjct: 6 GIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSTNTYYYTNVMSKLFLDTQSDSGVTFKAISNMDDFWSYLQGPMLDGLYWTKWYNNVSLTDNTNSLIYYENLLLGVPRMRQLKVKNNSCMVYKDFKDEIVGCFDVYSKDKEDTSQFGLINGTAWTYYTEEELGGSSYWGKITTYSGGGYYIDLELTKRDSLRQLQTLKSNLWLDRGTRAVFVDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTV 269 HSP 2 Score: 149.443 bits (376), Expect = 4.262e-37 Identity = 87/158 (55.06%), Postives = 120/158 (75.95%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGP 1486 YF S+WNILDV+VI +S + I F+I+RT+ V ++ +LL N + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+KD+ GFA+MFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF + NA+ + GP Sbjct: 311 YFTSIWNILDVIVILLSLVAIGFHIFRTMEVNRLMGTLLKNPTIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYDAIDNANRVLGP 468
BLAST of PKD2L-1 vs. Ensembl Xenopus
Match: PKD2L1 (polycystic kidney disease 2-like 1 [Source:NCBI gene;Acc:100495064]) HSP 1 Score: 249.595 bits (636), Expect = 9.024e-72 Identity = 125/264 (47.35%), Postives = 182/264 (68.94%), Query Frame = 3 Query: 147 GMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G+R +W T TE+ NR LYI+TTLREL +YIVFL + ++ +GMT+ Y+ TN+++ LF++ Q ++ +F ++++ DFW++ QGP+L+GLYW WYNN+++ + + IY+EN L+G+ R+RQ++V + SC++ +F+ I C+ YS E T FGL N TAWTY + LG G I+TY GGGYY+DL + + L L +NLW+DRGTRAV VDF+VYNANINLFCV++L+ EFPA GG IP + +TV Sbjct: 82 GIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSTNTYYYTNVMSKLFLDTQSDSGVTFKAISNMDDFWSYLQGPMLDGLYWTKWYNNVSLTDNTNSLIYYENLLLGVPRMRQLKVKNNSCMVYKDFKDEIVGCFDVYSKDKEDTSQFGLINGTAWTYYTEEELGGSSYWGKITTYSGGGYYIDLELTKRDSLRQLQTLKSNLWLDRGTRAVFVDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTV 345 HSP 2 Score: 149.443 bits (376), Expect = 7.589e-37 Identity = 87/158 (55.06%), Postives = 120/158 (75.95%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGP 1486 YF S+WNILDV+VI +S + I F+I+RT+ V ++ +LL N + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+KD+ GFA+MFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF + NA+ + GP Sbjct: 387 YFTSIWNILDVIVILLSLVAIGFHIFRTMEVNRLMGTLLKNPTIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYDAIDNANRVLGP 544
BLAST of PKD2L-1 vs. Ensembl Xenopus
Match: PKD2L1 (polycystic kidney disease 2-like 1 [Source:NCBI gene;Acc:100495064]) HSP 1 Score: 243.432 bits (620), Expect = 5.324e-70 Identity = 123/261 (47.13%), Postives = 179/261 (68.58%), Query Frame = 3 Query: 156 SIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 +W T TE+ NR LYI+TTLREL +YIVFL + ++ +GMT+ Y+ TN+++ LF++ Q ++ +F ++++ DFW++ QGP+L+GLYW WYNN+++ + + IY+EN L+G+ R+RQ++V + SC++ +F+ I C+ YS E T FGL N TAWTY + LG G I+TY GGGYY+DL + + L L +NLW+DRGTRAV VDF+VYNANINLFCV++L+ EFPA GG IP + +TV Sbjct: 23 GLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSTNTYYYTNVMSKLFLDTQSDSGVTFKAISNMDDFWSYLQGPMLDGLYWTKWYNNVSLTDNTNSLIYYENLLLGVPRMRQLKVKNNSCMVYKDFKDEIVGCFDVYSKDKEDTSQFGLINGTAWTYYTEEELGGSSYWGKITTYSGGGYYIDLELTKRDSLRQLQTLKSNLWLDRGTRAVFVDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTV 283 HSP 2 Score: 187.193 bits (474), Expect = 6.934e-50 Identity = 120/207 (57.97%), Postives = 159/207 (76.81%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKER 1633 YF S+WNILDV+VI +S + I F+I+RT+ V ++ +LL N + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+KD+ GFA+MFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF + NA+ + GP+YF+ YVFFV FVL NMFLAIINDTYSE+K EL NQKNE + D K++ Sbjct: 325 YFTSIWNILDVIVILLSLVAIGFHIFRTMEVNRLMGTLLKNPTIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYDAIDNANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELSNQKNELQFSDILKQQ 531
BLAST of PKD2L-1 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674]) HSP 1 Score: 237.654 bits (605), Expect = 1.767e-67 Identity = 120/270 (44.44%), Postives = 181/270 (67.04%), Query Frame = 3 Query: 135 RFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 + + +R +W T+ TE+ R Y++ REL YIVFL I+ ++ + M T M++ T ++ LF++G V + +F ++ + DFW F +GPL++GLYW+ WYNN + ++ +FIY+EN L+G+ RLRQ+RV + SC + + + IK CY +YS + E T PFGL+N TAWTYT++ +L G IS Y G GYY+DL ++ + + + L NNLW+DRGTRAV +DF+VYNAN+NLFCV++L+ EFPA GG+I + F+TV Sbjct: 21 KLLHRVRGLWGTRYTEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVSKDERTNFKTLLTMDDFWKFTEGPLMDGLYWDMWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTV 289 HSP 2 Score: 197.208 bits (500), Expect = 5.222e-53 Identity = 131/292 (44.86%), Postives = 195/292 (66.78%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTA 1888 YF+S+WN LD+V+IG+S I ++Y+ +V+ L L + N PN + L+Y+Q FN + A+ VF AWVK+FK+ +FN+TMTQLS+T+ RC+KD+ GFA+MFFIIF A+AQ YL+FGT++ F + IFT +RIILGDF F + A+ I GP+YF +VFF+ F+L NMFLAIINDTYSE+K ++ QK+E E+ D K+ + KL LKK + + ++ + G ++FDE + KG EIE++F++YD DG++ L NE +M++ LE ++ + Sbjct: 331 YFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTV----DDISESIRQGGGKLNFDELR-----KGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKERVS 613
BLAST of PKD2L-1 vs. Ensembl Mouse
Match: Pkd2 (polycystin 2, transient receptor potential cation channel [Source:MGI Symbol;Acc:MGI:1099818]) HSP 1 Score: 227.639 bits (579), Expect = 6.967e-120 Identity = 117/271 (43.17%), Postives = 168/271 (61.99%), Query Frame = 3 Query: 132 NRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGS--FNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 R G+R +W T+ E+ ANR Y+++ LREL Y+ FL +L I+ +GM + +Y+ T L+ LF++ V+ T F +++S DFW F +G L+GLYW + +N + +FI++EN L+G+ RLRQ+RV + SC I + + IK CY YS E PFG +N TAW YT + L G I++Y G GYY+DL + + L L N W+DRGTRA +DF+VYNANINLFCV++L+AEFPA GGV+P + F+ V Sbjct: 189 ERLVRGLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSN-HTQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPV 458 HSP 2 Score: 224.942 bits (572), Expect = 6.967e-120 Identity = 164/433 (37.88%), Postives = 262/433 (60.51%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHG-------------------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSE--EERKVKIGNMVQEELIKLNQDAVLTQ 2227 SYF+S WN LDVV++ +S + ++ NIYR + +L+ L + N PNF++++Y+Q FN + A+ VFL W+K+FK+I+FN+TM+QLS+T+ RC+KDL GF +MF IIF A+AQL YL+FGT++ F IFT +RIILGD F + A+ + GPLYF +VFF+ F+L NMFLAIIND+YSE+K++L QK E E+ D ++ Q L KL LK++ + +A++ + G ++FDE + ++ KG EIE++F++YD DG++ L E +M++ LE ++ ++ E S +P S ++F VS +E+Q L R++ ME+ I ++V KI+ V+ LE M+ +K KRR+ + ++L ++ L E + ++ +V+EEL + D +Q Sbjct: 499 SYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLLQ-FLEDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTV----DAISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLD----LEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDARLGRDSEIHREQMERLVREELERWESDDAASQ 922
BLAST of PKD2L-1 vs. Ensembl Mouse
Match: Pkd2l2 (polycystic kidney disease 2-like 2 [Source:MGI Symbol;Acc:MGI:1858231]) HSP 1 Score: 188.734 bits (478), Expect = 1.904e-90 Identity = 102/257 (39.69%), Postives = 155/257 (60.31%), Query Frame = 3 Query: 180 EDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQ-GSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 D+ R + TTL EL +Y +FL L I+ FGM MY+L ++++LFV+ + + SF S+ S +FW F +GPL++GLYW+SWY N + + IY+EN L+G+ R+RQ+RV + +C + FQ ++ CY Y+ + E FGL+ + WT+T + + P G + Y GGY V L + + +L N WI RGTRAV +DF++YNAN+NLFC+I+L+AEFPA GG++ + F +V Sbjct: 15 HDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSR--TAPWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSV 269 HSP 2 Score: 165.622 bits (418), Expect = 1.904e-90 Identity = 103/203 (50.74%), Postives = 150/203 (73.89%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNEL-INQKNEFEIG 1615 +YF+SVWN L+++++ + F+ + F Y + +L LL N + +P+F +L+Y+ +N ++AIT+F AW+KIFK+ISFN+TM+QLSSTL RC KD+ GFA+MFFIIF A+AQLG+L+FG+++ F SIF +RI+LGDF F A+ I GP+YF+ ++FFV FVL NMFLAIINDTYSE+K + I ++ +FE+G Sbjct: 310 AYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELG 512
BLAST of PKD2L-1 vs. Ensembl Mouse
Match: Pkd2l2 (polycystic kidney disease 2-like 2 [Source:MGI Symbol;Acc:MGI:1858231]) HSP 1 Score: 188.734 bits (478), Expect = 1.904e-90 Identity = 102/257 (39.69%), Postives = 155/257 (60.31%), Query Frame = 3 Query: 180 EDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQ-GSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 D+ R + TTL EL +Y +FL L I+ FGM MY+L ++++LFV+ + + SF S+ S +FW F +GPL++GLYW+SWY N + + IY+EN L+G+ R+RQ+RV + +C + FQ ++ CY Y+ + E FGL+ + WT+T + + P G + Y GGY V L + + +L N WI RGTRAV +DF++YNAN+NLFC+I+L+AEFPA GG++ + F +V Sbjct: 15 HDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSR--TAPWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSV 269 HSP 2 Score: 165.622 bits (418), Expect = 1.904e-90 Identity = 103/203 (50.74%), Postives = 150/203 (73.89%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNEL-INQKNEFEIG 1615 +YF+SVWN L+++++ + F+ + F Y + +L LL N + +P+F +L+Y+ +N ++AIT+F AW+KIFK+ISFN+TM+QLSSTL RC KD+ GFA+MFFIIF A+AQLG+L+FG+++ F SIF +RI+LGDF F A+ I GP+YF+ ++FFV FVL NMFLAIINDTYSE+K + I ++ +FE+G Sbjct: 310 AYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELG 512
BLAST of PKD2L-1 vs. Ensembl Mouse
Match: Pkd2l1 (polycystic kidney disease 2-like 1 [Source:MGI Symbol;Acc:MGI:1352448]) HSP 1 Score: 256.914 bits (655), Expect = 6.456e-74 Identity = 125/263 (47.53%), Postives = 179/263 (68.06%), Query Frame = 3 Query: 150 MRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 +R +W T TE+ NR LY++TTLREL +YIVFL + ++ +GMT+ + Y+ T +++ LF++ ++ SF +++S +DFW FAQGPLL+ LYW WYNN ++ + +FIY+EN L+G RLRQ+RV + SC++ +F++ I CY YS E PFG QN TAWTY Q LG G +++Y GGGYY+DLP + ++ L L LW+DRGTR V +DF+VYNANINLFC+++L+ EFPA GG IP + +TV Sbjct: 77 IRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTV 339 HSP 2 Score: 228.794 bits (582), Expect = 8.001e-64 Identity = 156/360 (43.33%), Postives = 237/360 (65.83%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEI---PNSESKKTFIHG---VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMD 2074 Y SVWNILD+VVI +S + + F+I+RT+ V ++ LL + + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+KD+ GFA+MFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF + NA+ I GP+YF+ YVFFV FVL NMFLAIINDTYSE+K EL QK++ ++ D+ K+ L +L L+K+++ +Q L + + F+++ + ++E G E +EI + F+R+D DG+ +LD EQ +M+ LE ++ +N EI + + P E G VS +E+ L R+ +++ V+ +V +I+ V L+ ++ Sbjct: 381 YLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLKGGEPE----IQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAVGSKLKMLE 736
BLAST of PKD2L-1 vs. Ensembl Mouse
Match: Pkd1l2 (polycystic kidney disease 1 like 2 [Source:MGI Symbol;Acc:MGI:2664668]) HSP 1 Score: 104.375 bits (259), Expect = 3.042e-22 Identity = 82/239 (34.31%), Postives = 119/239 (49.79%), Query Frame = 3 Query: 222 LRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFG-------LQNST----AWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVG 905 +RE+ Y+ FL +L+++A+G Y L F G F+ + F+ +A L+ LY + + D + +KL+G A +RQVRV + SC +A + Q + C+ YS IE +G NS AW Y Q+ P+ G ++ YGGGGY V L +D SA +L LF+N W+D TRAV V+FTVYNAN+NLFC + L E +G Sbjct: 1943 IREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSFSQG-------FSPVLGFRGFFEWANTTLVKNLYGH--HPGFVTDGN--------SKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLG 2164 HSP 2 Score: 61.6178 bits (148), Expect = 4.002e-9 Identity = 51/186 (27.42%), Postives = 97/186 (52.15%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSE 1570 YF S WN+L+V +I S+ ++ + RT+ L+ + ++ +F + Y++A V L+ VK++ + N M ++S L R D++GF + I+ A++ L+FG KL ++ L + T+ + LG F +++ L+ I G L + F+ FV+ N+F+++I +SE Sbjct: 2217 YFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHRDEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVAFSE 2402
BLAST of PKD2L-1 vs. UniProt/SwissProt
Match: sp|O35245|PKD2_MOUSE (Polycystin-2 OS=Mus musculus OX=10090 GN=Pkd2 PE=1 SV=2) HSP 1 Score: 227.639 bits (579), Expect = 4.236e-119 Identity = 117/271 (43.17%), Postives = 168/271 (61.99%), Query Frame = 3 Query: 132 NRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGS--FNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 R G+R +W T+ E+ ANR Y+++ LREL Y+ FL +L I+ +GM + +Y+ T L+ LF++ V+ T F +++S DFW F +G L+GLYW + +N + +FI++EN L+G+ RLRQ+RV + SC I + + IK CY YS E PFG +N TAW YT + L G I++Y G GYY+DL + + L L N W+DRGTRA +DF+VYNANINLFCV++L+AEFPA GGV+P + F+ V Sbjct: 189 ERLVRGLRGLWGTRLMEESNANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDTPVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSN-HTQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPV 458 HSP 2 Score: 224.942 bits (572), Expect = 4.236e-119 Identity = 164/433 (37.88%), Postives = 262/433 (60.51%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHG-------------------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSE--EERKVKIGNMVQEELIKLNQDAVLTQ 2227 SYF+S WN LDVV++ +S + ++ NIYR + +L+ L + N PNF++++Y+Q FN + A+ VFL W+K+FK+I+FN+TM+QLS+T+ RC+KDL GF +MF IIF A+AQL YL+FGT++ F IFT +RIILGD F + A+ + GPLYF +VFF+ F+L NMFLAIIND+YSE+K++L QK E E+ D ++ Q L KL LK++ + +A++ + G ++FDE + ++ KG EIE++F++YD DG++ L E +M++ LE ++ ++ E S +P S ++F VS +E+Q L R++ ME+ I ++V KI+ V+ LE M+ +K KRR+ + ++L ++ L E + ++ +V+EEL + D +Q Sbjct: 499 SYFRSFWNCLDVVIVVLSVVAMVINIYRMSNAEGLLQ-FLEDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTV----DAISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLD----LEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDARLGRDSEIHREQMERLVREELERWESDDAASQ 922
BLAST of PKD2L-1 vs. UniProt/SwissProt
Match: sp|Q9JLG4|PK2L2_MOUSE (Polycystic kidney disease 2-like 2 protein OS=Mus musculus OX=10090 GN=Pkd2l2 PE=2 SV=2) HSP 1 Score: 188.734 bits (478), Expect = 1.158e-89 Identity = 102/257 (39.69%), Postives = 155/257 (60.31%), Query Frame = 3 Query: 180 EDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQ-GSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 D+ R + TTL EL +Y +FL L I+ FGM MY+L ++++LFV+ + + SF S+ S +FW F +GPL++GLYW+SWY N + + IY+EN L+G+ R+RQ+RV + +C + FQ ++ CY Y+ + E FGL+ + WT+T + + P G + Y GGY V L + + +L N WI RGTRAV +DF++YNAN+NLFC+I+L+AEFPA GG++ + F +V Sbjct: 15 HDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSR--TAPWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSV 269 HSP 2 Score: 165.622 bits (418), Expect = 1.158e-89 Identity = 103/203 (50.74%), Postives = 150/203 (73.89%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNEL-INQKNEFEIG 1615 +YF+SVWN L+++++ + F+ + F Y + +L LL N + +P+F +L+Y+ +N ++AIT+F AW+KIFK+ISFN+TM+QLSSTL RC KD+ GFA+MFFIIF A+AQLG+L+FG+++ F SIF +RI+LGDF F A+ I GP+YF+ ++FFV FVL NMFLAIINDTYSE+K + I ++ +FE+G Sbjct: 310 AYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELG 512
BLAST of PKD2L-1 vs. UniProt/SwissProt
Match: sp|Q9NZM6|PK2L2_HUMAN (Polycystic kidney disease 2-like 2 protein OS=Homo sapiens OX=9606 GN=PKD2L2 PE=2 SV=2) HSP 1 Score: 184.882 bits (468), Expect = 1.323e-85 Identity = 101/256 (39.45%), Postives = 155/256 (60.55%), Query Frame = 3 Query: 180 EDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 + + + I TTL+EL +Y +FL L I+ FGM MY+L ++++LF++ V +F S+ S DFW F +GPLL GLYW+SWYNN + + + IY+EN L+G+ R+RQ++V + +C + + FQ ++ CY Y++ E FGLQ +T W Y+ +N S G + Y GGY L + + +L N WI RGTR + +DF++YNAN+NLFC+I+L+AEFPA GG++ + F +V Sbjct: 15 HKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQINTEWRYS-TSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSV 269 HSP 2 Score: 155.992 bits (393), Expect = 1.323e-85 Identity = 139/381 (36.48%), Postives = 223/381 (58.53%), Query Frame = 2 Query: 932 NC*ITEILFXXXXXXXXXXXXXXXXXSYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNEL-INQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENM 2071 +C IT +F+ +T +E+ +IK K +YFKS+WN L+++++ + F+ + FN Y V + +L LL + ++ +F +L+ + +N ++AIT+F AW+KIFK+ISFNKTM+QLSSTL RC KD+ GFA+MFFIIFFA+AQLG+L+FG+++ F SIF +RI+LGDF F A+ I GP+YF+ ++FFV FVL NMFLAIINDTYSE+K + I ++ +FE+G K+ + + + L+ A + D G D E + +GF D N + +A + + + +LE K + EI + + E ++ F++ V E+E ++ + LK+N V++ + + Sbjct: 284 SCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNV--------LEKFRLKKAQKDEDKKTKGSGDLAE---QARREGF--------------DENEIQNAEQMKKWKERLE--KKYYSMEIQDDYQPVTQEEFRELFLYAV-------------ELEKELHYINLKLNQVVRKVSAL 624
BLAST of PKD2L-1 vs. UniProt/SwissProt
Match: sp|Q9P0L9|PK2L1_HUMAN (Polycystic kidney disease 2-like 1 protein OS=Homo sapiens OX=9606 GN=PKD2L1 PE=1 SV=1) HSP 1 Score: 259.61 bits (662), Expect = 8.736e-74 Identity = 127/268 (47.39%), Postives = 177/268 (66.04%), Query Frame = 3 Query: 135 RFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G+R +W T TE+ NR LYI+TTLREL +YIVFL + ++ +GMT+ + Y+ T +++ LF++ + SF +++S ADFW FAQGPLL+ LYW WYNN ++ +FIY+EN L+G+ RLRQ++V + SC++ +F++ I CY YS E PFG N TAWTY Q LG G +++Y GGGYY+DLP + + L L LW+DRGTR V +DF+VYNANINLFCV++L+ EFPA GG IP + +TV Sbjct: 72 HICQGIRGLWGTTLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDFAQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTV 339 HSP 2 Score: 227.639 bits (579), Expect = 2.451e-62 Identity = 160/363 (44.08%), Postives = 235/363 (64.74%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEI---ESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHG------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMD 2074 Y S+WNILD+VVI +S + + F+I+RT+ V ++ LL N + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+KD+ GFAVMFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF + NA+ I GP YF+ YVFFV FVL NMFLAIINDTYSE+K EL QK+E ++ D K+ L +L L+K+++ +Q L + + F+++ ++E G +EI + F+++D DGNR+LD EQ +M+ LE ++ A+N EI I +S K+ VS +E+ L R+ ++E V+ +V +I+ V L+ ++ Sbjct: 381 YLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQE----IQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLE 739
BLAST of PKD2L-1 vs. UniProt/SwissProt
Match: sp|A2A259|PK2L1_MOUSE (Polycystic kidney disease 2-like 1 protein OS=Mus musculus OX=10090 GN=Pkd2l1 PE=1 SV=1) HSP 1 Score: 256.914 bits (655), Expect = 4.516e-73 Identity = 125/263 (47.53%), Postives = 179/263 (68.06%), Query Frame = 3 Query: 150 MRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 +R +W T TE+ NR LY++TTLREL +YIVFL + ++ +GMT+ + Y+ T +++ LF++ ++ SF +++S +DFW FAQGPLL+ LYW WYNN ++ + +FIY+EN L+G RLRQ+RV + SC++ +F++ I CY YS E PFG QN TAWTY Q LG G +++Y GGGYY+DLP + ++ L L LW+DRGTR V +DF+VYNANINLFC+++L+ EFPA GG IP + +TV Sbjct: 77 IRGLWGTTLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDSGVSFQTISSMSDFWDFAQGPLLDSLYWTKWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGPQNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTV 339 HSP 2 Score: 228.794 bits (582), Expect = 5.597e-63 Identity = 156/360 (43.33%), Postives = 237/360 (65.83%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEI---PNSESKKTFIHG---VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMD 2074 Y SVWNILD+VVI +S + + F+I+RT+ V ++ LL + + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+KD+ GFA+MFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF + NA+ I GP+YF+ YVFFV FVL NMFLAIINDTYSE+K EL QK++ ++ D+ K+ L +L L+K+++ +Q L + + F+++ + ++E G E +EI + F+R+D DG+ +LD EQ +M+ LE ++ +N EI + + P E G VS +E+ L R+ +++ V+ +V +I+ V L+ ++ Sbjct: 381 YLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLKGGEPE----IQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERVTLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAVGSKLKMLE 736
BLAST of PKD2L-1 vs. TrEMBL
Match: A0A0H3YJL0 (PKD2L-1 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=PKD2L-1 PE=2 SV=1) HSP 1 Score: 689.878 bits (1779), Expect = 0.000e+0 Identity = 418/419 (99.76%), Postives = 419/419 (100.00%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDAVLTQKRKQNFKSDFEQN 2266 SYFKSVWNILDVVVIGISFICIIFNIYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPLYFLLYVFFVLFVLFNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMLAKLNLKKDKLDVLQNALTNADTNNDGLMDFDEWKTAMQEKGFES+EIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDNSKNKRRKSMRKILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDAVLTQKRKQNFKSDFEQN Sbjct: 355 SYFKSVWNILDVVVIGISFICIIFNIYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPLYFLLYVFFVLFVLFNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMLAKLNLKKDKLDVLQNALTNADTNNDGLMDFDEWKTAMQEKGFESHEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDNSKNKRRKSMRKILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDAVLTQKRKQNFKSDFEQN 773 HSP 2 Score: 606.29 bits (1562), Expect = 0.000e+0 Identity = 311/312 (99.68%), Postives = 311/312 (99.68%), Query Frame = 3 Query: 3 KMAKGWSTEDMKANVEYDAYDEISHADSVSFDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 KMAKGWSTEDMKANVEYDAYDEISHADSVS DNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTYGGGGYYVDLPSDQFSAFSLLNNLFNNLWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV Sbjct: 3 KMAKGWSTEDMKANVEYDAYDEISHADSVSLDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTYGGGGYYVDLPSDQFSAFSLLNNLFNNLWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 314
BLAST of PKD2L-1 vs. TrEMBL
Match: A0A077L755 (Transient receptor potential ion channel P a (Fragment) OS=Dugesia japonica OX=6161 GN=DjTRPPa PE=2 SV=1) HSP 1 Score: 509.605 bits (1311), Expect = 0.000e+0 Identity = 316/417 (75.78%), Postives = 353/417 (84.65%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSE--SKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDAVLTQKRKQNFKSD 2254 SYF SVWN LDV+VI ISF+C+IFNIYRT+AVQTIL LLMN NQHPNFD LSY Q TFNYLLA+TVFLAWVKIFKYISFNKTMTQLS+TLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFG +L FRELHYSIFTLYRIILGDFTF DF II GPLYF+LYVFFV FVLFNMFLAIINDTYSE+KNEL N KNEFEIGDYFKERT ML KLNLKK+K+ +QNA+TNADTNNDGLMDF+EWK AM+ +GFE EIE+VFS+YDTDGNRVLD EQIEMQ QLEN K VN EI+ EQ+E+ + + KK I GVSIDEY LN R+EEMEN I ++V KI+ VL++LENMD +K KRRK+M KIL L+SKEHLSEEERKV++ MVQEELIKL+ D VLTQ+R+ N KSD Sbjct: 312 SYFHSVWNCLDVIVISISFVCVIFNIYRTIAVQTILGDLLMNSNQHPNFDNLSYNQTTFNYLLAVTVFLAWVKIFKYISFNKTMTQLSTTLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFGAQLQSFRELHYSIFTLYRIILGDFTFSDFQTVHIILGPLYFILYVFFVFFVLFNMFLAIINDTYSEVKNELANVKNEFEIGDYFKERTIKMLEKLNLKKEKIADIQNAITNADTNNDGLMDFEEWKAAMKVRGFEESEIENVFSKYDTDGNRVLDQTEQIEMQRQLENLKAEVNNEIMVEQAELTDCDLGLKKGVIRGVSIDEYNILNSRVEEMENNIISMVSKIDMVLRNLENMDKAKAKRRKAMGKILNTLTSKEHLSEEERKVQLETMVQEELIKLDHDTVLTQRRRSNHKSD 728 HSP 2 Score: 329.717 bits (844), Expect = 0.000e+0 Identity = 176/252 (69.84%), Postives = 209/252 (82.94%), Query Frame = 3 Query: 186 IKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNS-MASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 +K NR+LYIQTTLREL +YI+FLAILMIIAFGMTTGTMYW TNLL+NLF+NG NN + M++ ADFW FA G LLNGLYWN+WYNNLN+D SEINFI++ENKLIGL R+RQVR+ + +CII EF+ I+ +CY +Y EST+ FGLQNSTAW YT + LGS P QG+ISTY GGG+Y+DLP DQ +A +LN L+ NLWIDRGTRAVI+DFTVYNANINLFCVIKL+AEFPAVGGVIP YDF+T+ Sbjct: 20 VKGNRDLYIQTTLRELILYIIFLAILMIIAFGMTTGTMYWYTNLLSNLFLNGNGNNNTNTFLTMSADADFWNFATGALLNGLYWNTWYNNLNLDPSEINFIFYENKLIGLPRMRQVRMKNNTCIIPLEFKNIVNQCYASYKMSDESTDSFGLQNSTAWNYTSGSVLGSYPFQGTISTYSGGGFYIDLPIDQPTALGVLNFLYTNLWIDRGTRAVIIDFTVYNANINLFCVIKLVAEFPAVGGVIPTYDFRTI 271
BLAST of PKD2L-1 vs. TrEMBL
Match: R7T913 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_169289 PE=4 SV=1) HSP 1 Score: 321.627 bits (823), Expect = 7.127e-164 Identity = 215/422 (50.95%), Postives = 296/422 (70.14%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREI---------------------ISEQSEIPNSESK------KTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEEL 2194 YFKS WNILD++V+ I+ CI FN+YRTVAV +L++LL + N++ +F++LSY+Q FN LAI VF AW+K+FKYISFNKTMTQLSSTL RC+KDLAGFAVMFFIIF AFAQLGYL+FGT++ F ++FTL+RIILGDF F + A+ + GP YF+LYVFFV FVL NMFLAIINDTYSE+K E+ NQKNEFE+GDYFK+ ML KLNLK+DK+ +Q AL AD NND +DFDEW+ ++ +G+ EIE+VF++YD DG+RVLD EQ +MQ LE QK +++E E+ E ++S + ++GVS +E+ L+ R++ ME+ I ++V KI+ VL LE M+ +K+KRR++M KIL ++ + ++E ++ ++ ++V+EEL Sbjct: 326 GYFKSFWNILDIIVLMIAVCCIGFNVYRTVAVADMLDTLLDSPNEYADFEFLSYWQVVFNSALAIMVFFAWIKVFKYISFNKTMTQLSSTLARCAKDLAGFAVMFFIIFLAFAQLGYLIFGTQVKDFSSFDDAVFTLFRIILGDFNFHELEQANRVLGPAYFILYVFFVFFVLLNMFLAIINDTYSEVKEEISNQKNEFEMGDYFKQGYNKMLDKLNLKRDKIVDIQKALQTADINNDDRLDFDEWRQELKTRGYAEAEIEAVFAKYDIDGDRVLDKTEQRKMQADLEGQKAKLSKEYDQLENKGDAKGSRVSFDSDENTDEEDESHGTKSSSRGGSNRNVVNGVSYEEFTVLSRRVDRMEHSIGSIVSKIDAVLVKLEAMEKAKSKRRETMSKILDSITESDGTTDEVKRHQMEHLVREEL 747 HSP 2 Score: 288.115 bits (736), Expect = 7.127e-164 Identity = 142/273 (52.01%), Postives = 203/273 (74.36%), Query Frame = 3 Query: 123 GFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNT-GSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G W++FS G+RS+WAT+ TE+IK N+ L+I+TTLREL +YIVFL IL I+ FGMT+ TMY+ T +++ LF++ Q T +F M + DFW FA+ PL++GLYW +WYN+ NV E+ +I++ENKL+G+ R+RQ++V + SC++ ++F++ IK CY TY++ IE PFGL N +AW+Y+ + L G I+TYGGGG+Y DL ++ + +L+ +L NLW+DRGTR V VDFTVYNANINLFCVI+L+ EFPA GG IP ++F+TV Sbjct: 13 GCWHKFSQGIRSLWATRHTEEIKDNQELHIKTTLRELVVYIVFLVILCIVTFGMTSSTMYYYTKVMSELFLDSQFPETKNTFRGMTTMHDFWRFAESPLVDGLYWETWYNDRNVSSDELGYIFYENKLLGVPRVRQLKVRNDSCVVHDDFKENIKACYDTYASSIEDKNPFGLINGSAWSYSSEDELDGSSHWGYITTYGGGGFYQDLALNKADSLALIADLKQNLWLDRGTRVVFVDFTVYNANINLFCVIRLVVEFPATGGAIPSWNFRTV 285
BLAST of PKD2L-1 vs. TrEMBL
Match: A0A267E5C4 (EF-hand domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009305g2 PE=4 SV=1) HSP 1 Score: 318.931 bits (816), Expect = 4.912e-163 Identity = 219/440 (49.77%), Postives = 296/440 (67.27%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSE-----------------------------IPNSESKKTFIHG----------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEEL 2194 +YF S WN LD+VVI I+ +C FNIYRT++V L LL ++ Q+P+FD+LS++Q FN +AITVF AWVKIFKYISFNKTMTQLSSTLG C+KDL GFAVMFFI+FFAFAQLGYL+FGTK+ FRE +IFTL+RIILGDF F NA + GP+YF+LYVFFV FVL NMFLAIINDTYSE+K+ L NQ N+FE+ DYFK+R +L KL+L++DK+ +Q A+ +AD NND +DF+EW+T ++ +G+ EIE++F+RYD DG+RVLD EQ +MQ +LE QK A+N +I SE++E + S ++ G V IDE+ L+ R++ ME+ I +V +I+ VL LE+M+ +K KRR++M ++L + E SE E++ K+ MV++EL Sbjct: 412 AYFSSFWNWLDIVVIVIALVCAAFNIYRTISVGNKLTRLLEDETQYPDFDFLSFWQEQFNQAIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLLGFAVMFFIVFFAFAQLGYLIFGTKVEDFREFQQAIFTLFRIILGDFDFASLQNAHRVLGPIYFILYVFFVFFVLINMFLAIINDTYSEVKSNLANQPNDFEMTDYFKQRAGRVLDKLHLRRDKIVDIQRAMQSADMNNDRQLDFEEWRTELKMRGYADGEIEALFARYDMDGDRVLDEEEQRKMQWELEGQKAALNSQIESERAEQQRQGSAGVGADDGDADNDELAGDDRDGAVSLRGSMRSATRGGRPNTSGSNSGGGGSGVPIDEFTTLSRRVDRMEHSIGGIVNRIDSVLLKLESMERAKLKRRETMSRLLDSIGKCEGDSEAEKREKMERMVRQEL 851 HSP 2 Score: 287.73 bits (735), Expect = 4.912e-163 Identity = 148/290 (51.03%), Postives = 200/290 (68.97%), Query Frame = 3 Query: 72 SHADSVSFDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 S A + +N + G W +F G+R++W TK TED+ N L I+TTLREL +Y +FL ++ I+ FGMT+ TMY+ T ++N+LF+ + +F S+ + AD+W FAQGPL++GLYW++WYNN NV D E NFIY+ENKL+G+ R+RQVRV + SC IA +F+ I+ CY YS ES EPFG NSTAW Y+ + L G ++TY GGGYY+DL + + + ++ LF+ LWIDR TRAV +DFTVYNANINLFCVIKLIAEFPA GG ++F+TV Sbjct: 82 SQAAIMPANNGTDDEATGCWGKFKRGVRAVWMTKDTEDVSQNAELKIKTTLRELVMYCLFLVVICILTFGMTSSTMYYYTFVMNSLFLTTPTASGATFTSVKNFADWWGFAQGPLISGLYWDTWYNNANVTDPRERNFIYYENKLLGVPRMRQVRVRNDSCSIATDFRANIRACYAMYSRSAESREPFGYMNSTAWNYSTEQQLDGRGYSGKLATYNGGGYYIDLGRSREESTAKIDELFHGLWIDRATRAVFIDFTVYNANINLFCVIKLIAEFPATGGGFTSWEFRTV 371
BLAST of PKD2L-1 vs. TrEMBL
Match: A0A267G6B3 (EF-hand domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009305g3 PE=4 SV=1) HSP 1 Score: 317.775 bits (813), Expect = 1.712e-162 Identity = 219/440 (49.77%), Postives = 297/440 (67.50%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSE-----------------------------IPNSESKKTFIHG----------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEEL 2194 +YF S WN LD+VVI I+ +C FNIYRT++V L LL ++ Q+P+FD+LS++Q FN +AITVF AWVKIFKYISFNKTMTQLSSTLG C+KDL GFAVMFFI+FFAFAQLGYL+FGTK+ FRE +IFTL+RIILGDF F NA + GP+YF+LYVFFV FVL NMFLAIINDTYSE+K+ L NQ N+FE+ DYFK+R +L KL+L++DK+ +Q A+ +AD NND +DF+EW+T ++ +G+ EIE++F+RYD DG+RVLD +EQ +MQ +LE QK A+N +I SE++E + S ++ G V IDE+ L+ R++ ME+ I +V +I+ VL LE+M+ +K KRR++M ++L + E SE E++ K+ MV++EL Sbjct: 412 AYFSSFWNWLDIVVIVIALVCAAFNIYRTISVGNKLTRLLEDETQYPDFDFLSFWQEQFNQAIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLLGFAVMFFIVFFAFAQLGYLIFGTKVEDFREFQQAIFTLFRIILGDFDFASLQNAHRVLGPIYFILYVFFVFFVLINMFLAIINDTYSEVKSNLANQPNDFEMTDYFKQRAGRVLDKLHLRRDKIVDIQLAMQSADMNNDRQLDFEEWRTELKMRGYADGEIEALFARYDMDGDRVLDEDEQRKMQWELEGQKAALNSQIESERAEQQRQGSAGVGADDGDADNDELAGDDRDGAVSLRGSMRSATRGGRPNTSGSNSGGGGSGVPIDEFTTLSRRVDRMEHSIGGIVNRIDSVLLKLESMERAKLKRRETMSRLLDSIGECEGDSEAEKREKMERMVRQEL 851 HSP 2 Score: 286.96 bits (733), Expect = 1.712e-162 Identity = 148/290 (51.03%), Postives = 200/290 (68.97%), Query Frame = 3 Query: 72 SHADSVSFDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV-DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 S A + +N + G W +F G+R++W TK TED+ N L I+TTLREL +Y +FL ++ I+ FGMT+ TMY+ T ++N+LF+ + +F S+ + AD+W FAQGPL++GLYW++WYNN NV D E NFIY+ENKL+G+ R+RQVRV + SC IA +F+ I+ CY YS ES EPFG NSTAW Y+ + L G ++TY GGGYY+DL + + + ++ LF+ LWIDR TRAV +DFTVYNANINLFCVIKLIAEFPA GG ++F+TV Sbjct: 82 SQAAIMPANNGTDDEATGCWGKFKRGVRAVWMTKDTEDVSQNAELKIKTTLRELVMYCLFLVVICILTFGMTSSTMYYYTFVMNSLFLTTPTASGATFTSVKNFADWWGFAQGPLISGLYWDTWYNNANVTDPRERNFIYYENKLLGVPRMRQVRVRNDSCSIATDFRANIRACYAMYSGSAESREPFGYMNSTAWNYSTEQQLDGRGYSGKLATYNGGGYYIDLGRSREESTAKIDELFHGLWIDRATRAVFIDFTVYNANINLFCVIKLIAEFPATGGGFTSWEFRTV 371
BLAST of PKD2L-1 vs. Ensembl Cavefish
Match: pkd2l1 (polycystic kidney disease 2-like 1 protein [Source:NCBI gene;Acc:103031316]) HSP 1 Score: 240.736 bits (613), Expect = 6.899e-127 Identity = 125/264 (47.35%), Postives = 179/264 (67.80%), Query Frame = 3 Query: 147 GMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G++ +W T T+D NR L+++TTLREL +YIVFL + ++ +GMT+ T Y+ T ++ +LFVN ++ +F S+ + DFW++AQGPLL+GLYW SWYNN ++ +FIY+EN L+G+ R+RQ++V +KSC + +F++ I C+ Y+ + E FGL N TAW Y + L G ++TY GGGYY DL + + +L NL NNLW+D GTRAV +DF+ YNANINLFCVI+L+ EFPA GG IP Y +TV Sbjct: 95 GIKGLWGTTLTKDTTENRELFVRTTLRELVVYIVFLVDMCLLTYGMTSSTTYYYTKVMTDLFVNAPSDSGVTFQSIGTMDDFWSYAQGPLLDGLYWTSWYNNQSLQTGTHSFIYYENMLLGVPRVRQLKVKNKSCKVHKDFEEEISDCFDVYNEKKEDDSSFGLINGTAWQYHTEKELKGSNHWGMLATYSGGGYYQDLALTKEESAGVLANLNNNLWLDHGTRAVFIDFSTYNANINLFCVIRLVVEFPATGGAIPSYQIRTV 358 HSP 2 Score: 234.958 bits (598), Expect = 6.899e-127 Identity = 171/396 (43.18%), Postives = 261/396 (65.91%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIIS-----EQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMV 2182 SYFKS+WNILDVV+I ++ + I+FN++RT+ V +L +LL + + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLSSTL RC+ D+ GFA+MFFI+FFA+AQLGYLLFGT++ F H IFT +RIILGDF + A+ + GP+YF YVFFV FVL NMFLAIINDTYSE+K EL +QK++ +I D K+ KL LKK+K+ +Q L + ++F +++ ++E G +EI + FS++D DGN++LD EQ M+ +LE ++ A++ E+ + E++ +++KT V+ ++Q L ++ E+E + T + KI+ V++ L D K ++ + K LTI +E+ER V GN++ Sbjct: 399 SYFKSIWNILDVVIIMLAIVAIVFNVFRTIKVDKLLGNLLKEPSIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCATDILGFAIMFFIVFFAYAQLGYLLFGTEVESFSTFHKCIFTQFRIILGDFDYDGIERANRVLGPIYFFTYVFFVFFVLLNMFLAIINDTYSEVKEELASQKDDLQITDLIKQSYSKTFMKLKLKKEKISDVQKVLRSGSKE----LEFKDFRETLKEMGHADHEISAAFSKFDYDGNQILDKEEQETMKQELEEKRDALSVELHNLGINYEKNGKETDDNEKTNSVLVTAQQFQMLVKQVVELECSLATTMAKIDVVMEKLGLQDAGKTNKKDATGKHLTI------RNEQERPVSGGNVL 784
BLAST of PKD2L-1 vs. Ensembl Cavefish
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:103043751]) HSP 1 Score: 237.269 bits (604), Expect = 3.582e-66 Identity = 175/436 (40.14%), Postives = 264/436 (60.55%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHG-------------------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSE--EERKVKIGNMVQEELIKLNQDAVLTQKRKQ 2239 YFKS+WN LDV+++ +S II NIYRT AV L LL N + +PNF L+ Q FN+L A+ VFLAWVK+FK+I+FNKTM+QLS+T+ RC+KDL GFA+MFFI+F A+AQL YL+FG +L F IFT +RIILGDF F + + + GP+YF +VFF+ +L NMFLAIINDTYSE+K ++ Q++E EI D K+ Q + KL L+K +D + ++L A G ++FDE + ++ KG EIE++F++YD DG++ L +E +M++ LE ++ ++ E+S +P S ++F VS +E+Q L R++ ME+ I ++V KI+ V+ LE M+ +K KRR+ + ++L + E + E + + +V+EEL + D ++Q Q Sbjct: 441 YFKSLWNCLDVIIVTLSAPAIIMNIYRTSAVSNRLRYLLENHSTYPNFQPLAQVQVQFNHLAAVIVFLAWVKLFKFINFNKTMSQLSTTMSRCAKDLLGFAIMFFIVFLAYAQLAYLVFGNQLNDFSTFQACIFTQFRIILGDFDFSEIEETNRVLGPIYFTTFVFFMFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKGYQKAMVKLRLRKTTVDDISDSLRQA----GGKLNFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELSEHEHQQMKDDLEKEREDLDL----ERSSLPRPMSGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLDGVMEDERMGRDTEVHREHMEKLVREELERWESDDAISQVSHQ 868 HSP 2 Score: 228.409 bits (581), Expect = 5.408e-63 Identity = 113/277 (40.79%), Postives = 182/277 (65.70%), Query Frame = 3 Query: 114 VKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN--NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 +++G+ R +R +W T+ ED +++R +Y++ LRE YI FL L II +GM + MY+ T +++ LF++ ++ + +F ++++ DFW + +GP LNG+YW+ WYNN ++ +++ + IY+EN L+G+ RLRQV+V +KSC + + + + CY YS E PFGL+N+TAW Y+ + LG G ++TY GGGYY DL + + L L +NLW+DRGTRAV +DF+VYN N+NLFC+++++ EFPA GG + + F+TV Sbjct: 124 MQHGWGKRILAKLRILWGTRLMEDSESSREVYLKNVLRETVTYIFFLITLCIITYGMVSTNMYFYTKVMSQLFLDTPLSKGDPTTFKTLSTMEDFWKYTEGPFLNGMYWDVWYNNKSLPENQ-SLIYYENLLLGVPRLRQVKVLNKSCPVHEDLKDEVYDCYSIYSPASEDKAPFGLKNNTAWVYSEENILGESSYWGEVATYRGGGYYQDLARSREESARQLKELKDNLWLDRGTRAVFLDFSVYNGNVNLFCIVRMLVEFPATGGAVTSWQFQTV 399
BLAST of PKD2L-1 vs. Ensembl Cavefish
Match: pkd1l2a (polycystin 1 like 2 [Source:NCBI gene;Acc:103044173]) HSP 1 Score: 116.316 bits (290), Expect = 4.611e-26 Identity = 97/306 (31.70%), Postives = 151/306 (49.35%), Query Frame = 3 Query: 45 VEYDAYDEISHADSVSFDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTT-----LRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFEN-KLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFG----------LQNS--TAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGG 908 V+ + Y ++ ++ +D + V+ F R S S + +I+ RN I+ +RE+ IY+ FL +L+++A+G ++LT + F NG + + + + +A LLN L+ + FI N KL+G ARLRQVRV D SC + + + C+ YS +E +G L + T W Y Q+ L + PI G ++ Y GGG+ VDL ++ +A S L LF N W+D TRA+ V+FTVYNAN+NLFC++ L+ E AVG Sbjct: 2030 VDQEEYGDVPIDGNLPNSDDPDAVR--FARRDSTC--SFYQPPPPSNIEKMRNNMIKEQKVFGLIREILIYMGFLWMLLLVAYGQRDPNAFYLTQHIQQSFSNG-------ISDSMTHGEVFQWANSTLLNNLFGQ-----------QPGFITDGNSKLVGNARLRQVRVQDGSCRVDRSMRNSVPDCHAPYSWDMEDLGSYGPGWNPSIDANLSKTLPTPWQYQTQSRLRAHPIWGGVAVYRGGGFVVDLGPNRENASSSLQYLFENTWLDMFTRAIFVEFTVYNANVNLFCIVTLMFETTAVGA 2313 HSP 2 Score: 69.707 bits (169), Expect = 1.210e-11 Identity = 61/204 (29.90%), Postives = 110/204 (53.92%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQK--NEFEIGD 1618 YF+S WN+LD+ +I +S+ + I RT+ +E + +++ F+ + Y++A V LA VK++ + N + ++STL R D++GF V+ I+F A++ LL+G KL +R L + T+ + LG F +++ L+ + + G + F+ FV+ N+F+++I +SE E I+ K E EI D Sbjct: 2365 YFRSKWNLLDMAIIILSWSALPVFIKRTLLGNQSIEYYQNHKDEYAGFNETATADAVLGYIIAFLVLLATVKLWHLLRLNPKLHMITSTLQRAWNDISGFIVVMTIMFLAYSVACNLLYGWKLYSYRTLLNAAQTIVSLQLGIFNYEEVLDYNPVLGAFIVGSCIIFMTFVVLNLFISVILVAFSE---EQIHHKPSEEEEIVD 2565
BLAST of PKD2L-1 vs. Ensembl Cavefish
Match: ENSAMXT00000006495.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:35007331:35041448:1 gene:ENSAMXG00000006274.2 transcript:ENSAMXT00000006495.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 104.76 bits (260), Expect = 1.574e-22 Identity = 81/239 (33.89%), Postives = 123/239 (51.46%), Query Frame = 3 Query: 228 ELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFG-----LQNS-------TAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGG 908 E+ IY+ F +L++ A+ ++LT + F NG + S D + +A LL L+ Y+ D + +KL+G ARLRQVRV SC A+ + + C+ YS ++E +G L +S T W Y Q+ L + + G ++ Y GGG+ VDL DQ ++ S+L LF N W+D TRA+ ++FTVYNAN+NLFC++ L+ E AVG Sbjct: 1211 EILIYLGFFCMLLMAAYSQRDPNAFFLTRHIQQSFSNG-------ISDSMSQQDVFIWANSSLLTNLFGQ--YSGFITDGN--------SKLVGTARLRQVRVQKSSCRKASSVRSSVPDCHAPYSWEVEDMGSYGPGWTSLIDSNMSKALFTPWQYQTQSRLRAHTVWGGMALYRGGGFVVDLEPDQQNSSSVLQYLFENAWLDIYTRALFIEFTVYNANVNLFCIVTLMLETTAVGA 1432 HSP 2 Score: 54.6842 bits (130), Expect = 4.256e-7 Identity = 50/186 (26.88%), Postives = 100/186 (53.76%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSE 1570 YF++ WNIL++ +I +S+ I + V L+ + NQ P+F + YL A+ V LA +K++ + N + +++TL + D++ F V+ I+F A++ + LLFG KL ++ L + + + LG F +++ L+ + + G + F+ FV+ N+F+++I + +S+ Sbjct: 1482 YFRNKWNILELAIILLSWSAFSVFIKKMVQGDQDLKYYQDHRNQFPSFYETAAADSVLGYLTAVLVLLATIKMWHLMRLNSKLNMITNTLQQAWSDISSFIVVIVIMFLAYSIVSNLLFGWKLYTYKTLIDAATAMVSLQLGIFNYEEILDLNPVLGAFIIGSCIIFMTFVVLNLFISVILEAFSQ 1667
BLAST of PKD2L-1 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558]) HSP 1 Score: 247.669 bits (631), Expect = 2.835e-72 Identity = 169/351 (48.15%), Postives = 243/351 (69.23%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLE 2065 YFKSVWN LD++VI +S + IIFNI RT+AV +L +LL + N + +F+YL+++Q FN +LAI VF AW+KIFKY+SFNKT+TQLSSTL RC+KD+ GFAVMFFIIFFA+AQ GYL+FG+++ F IFT +RIILGDF F NA+ I GP+YF Y+FFV FVL NMFLAIINDTY+++K EL + K++FEIGD+FK+ + ML KL +KKD + +Q AL +A + +++D W+ + G EI + FS++D D + VLD +EQ +++ +LE QK +N +I E + ++ K V+ D++ R+ +ME+ +++L+ K+ +L LE Sbjct: 312 YFKSVWNCLDIIVIVLSMVAIIFNICRTIAVSNLLGALLNDPNIYADFEYLAFWQTQFNNMLAINVFFAWIKIFKYVSFNKTLTQLSSTLARCAKDVLGFAVMFFIIFFAYAQTGYLVFGSQVEDFSSFVNCIFTQFRIILGDFDFHAIENANRILGPIYFTTYIFFVFFVLLNMFLAIINDTYTDVKAELADTKDDFEIGDFFKQGYKNMLNKLKMKKDDIADMQRALDSAGKH----LEYDIWRKNLIRLGHSDEEIAAAFSKFDKDSDNVLDEDEQKQLRAELEGQKDKLNEDI--EALKTMDNSGKPGDASRVTKDDFNRFASRVAKMESSMDSLMSKVESLLTKLE 656 HSP 2 Score: 207.223 bits (526), Expect = 1.256e-57 Identity = 117/263 (44.49%), Postives = 159/263 (60.46%), Query Frame = 3 Query: 162 WATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN--NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEIN--FIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 W T+ TE + + R Y +TTLREL IY+VFL L ++ FGM Y+ T ++ +LFV V+ + +FNS++S DFW QGP+L+GLYW WYN DQ +N FI +EN ++G+ R+RQ++V + SC I F+ II CY YS E E FG TAW Y + L G ++ Y G GYY DL + + +L L + LW+D GTRAV +DFT YN NINLFCV++L+ EFP GG +P Y F+TV Sbjct: 12 WGTRLTE-VNSTREQYFKTTLRELIIYVVFLIDLCLLTFGMMNTNTYYYTKVMMDLFVESPVSPIDGTNFNSISSMDDFWKVVQGPVLDGLYWEKWYNG---DQLPVNLSFIQYENVMLGVPRVRQLKVRNGSCTIYPLFRNIIPGCYDGYSCGEEDKETFGRGTGTAWKYWSEEELSGSSHWGLLAQYSGAGYYRDLSRRKNESAPMLQELKDYLWLDHGTRAVFIDFTTYNGNINLFCVVRLVVEFPLTGGALPSYQFRTV 270
BLAST of PKD2L-1 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558]) HSP 1 Score: 226.868 bits (577), Expect = 6.357e-64 Identity = 146/293 (49.83%), Postives = 207/293 (70.65%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXX--XXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQK 1882 +YFKSVWN LD++VI +S + IIFN+YRTV V +L++LL N++ NF +L+++Q +N ++A+ VF W+K FKY+SFNKTMTQLSSTL RC+KD+ GFAVMFFIIFFA+AQLGYLLFGT++ F IFT +RIILGDF F NA+ + GPLYF YVF V + + NMFLAIINDTY+E+KNEL ++NEF++G YFK + + + K K V ++ +A + +++D+W+ ++ G EIE+ F+++D D N VLD+NE M+++L++QK Sbjct: 397 AYFKSVWNCLDLLVIMLSVVAIIFNVYRTVTVNKLLKALLDEPNRYGNFQFLAFWQTQYNNMVAVNVFFCWIKFFKYVSFNKTMTQLSSTLARCAKDVLGFAVMFFIIFFAYAQLGYLLFGTQVEDFSTFSNCIFTQFRIILGDFDFNAIENANRVLGPLYFTTYVFVVFFVLLPKNMFLAIINDTYAEVKNELAEKENEFDVGGYFK-KVYLDIRKKLGKNRGNIVDMISVLDASSQK---INYDDWRLKLKRLGHSDEEIEAAFAKFDKDKNSVLDSNEMKLMRDELKSQK 685 HSP 2 Score: 222.631 bits (566), Expect = 2.292e-62 Identity = 117/258 (45.35%), Postives = 174/258 (67.44%), Query Frame = 3 Query: 150 MRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQV--NNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIP 917 +R +W T+ TEDI +R+ Y++TTLRELF+YI FL L+I+ FGMT+ MY T ++NLF+ V N++ +FNS+ + DFW QGP+LNGLYW WYN++ + +++ +FIY+EN L+G+ R+RQ++V + SC + +FQK ++ CY YS E FG T W Y+ +++ G ++TY GGGYY+DL + + LL +LF+ W+DRGTRA+++DF+ YN NINLF VI+L+ EFP GG +P Sbjct: 94 LRGLWGTRLTEDI-TDRDKYVKTTLRELFVYIAFLINLIILTFGMTSDLMYKYTLAMDNLFLQNTVSPNDSVNFNSIFTFDDFWKVVQGPVLNGLYWEKWYNDIPLVENQ-SFIYYENFLLGVPRIRQLKVRNDSCTVHADFQKDVQGCYAAYSEDAEDKASFGPATGTPWKYSTSSDMNGSSHWGLLATYSGGGYYLDLTRSKSESAILLQDLFDKQWLDRGTRAILIDFSSYNGNINLFSVIRLLVEFPPTGGAVP 349
BLAST of PKD2L-1 vs. Ensembl Sea Lamprey
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387]) HSP 1 Score: 134.035 bits (336), Expect = 8.792e-33 Identity = 109/379 (28.76%), Postives = 187/379 (49.34%), Query Frame = 2 Query: 1184 FNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHG---------------------------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLS---EEERKVKIGNMVQEELIKLNQD 2212 F + + VF+AW+K+ ++ S +T+T L RC+ DL G+ ++F +F AFAQL +L+FG L F I T RI+LGDF F A I GP+YF+ YVF V ++ MFLAI+++ YSE K+E + + +F++ K+ + + + A G ++F W+ ++ +GF EIE+VF+RYD DG L EQ++M+ L +K + I S P + KK + VS +E++ L R+ +ME+ I ++V K++ V+ LE M+ + +RR + ++++ + +E S +E R+ + +V++EL + + D Sbjct: 359 FIIVTGVIVFVAWIKVVRFGSMCRTLTMCGCALTRCAWDLLGYTLVFATVFLAFAQLAFLIFGGALPDFSSFSSCILTQVRILLGDFDFSSLEAASRIMGPIYFVSYVFCVGLIMMVMFLAIVSEAYSEEKSEQAHSQPQFQLSSVIKQ-------VKVVDRLSCKKPRVAGIQKTLPPSGQINFATWRQNLKGQGFADAEIEAVFARYDGDG--ALTRAEQLQMRRDLRLEKQTIRLHI----SVSPREKKKKHQVTSRDDDDDDDDGDSDEDDDITVVRRGNHHQGGGGGVSREEFRVLVRRVNQMEHSIGSVVSKMDAVMVKLEAMERQRLRRRDVLSRLISGMGEEERGSWPGQEVRRDHMERLVRDELKRWDSD 724 HSP 2 Score: 117.087 bits (292), Expect = 2.700e-27 Identity = 86/280 (30.71%), Postives = 140/280 (50.00%), Query Frame = 3 Query: 159 IWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTG--SFNSMASSADFWTFAQGPLLNGLYW---NSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSC-IIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSD-QFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVI-------------PLYDFKTV 938 +WAT+ TE NR Y++ +RE + VFLA+L ++A+ Y T+ ++ +F + ++N +F+++A+ W G L L W NS NL + + EN ++ + Q RV + SC ++ CY YS+ E+ +PFG NST W + + +P QG++ YG GGY V LP+D + +A+ L L + W+DR TR + VD + N N+ L+ V++L EFP GG++ PL+D + V Sbjct: 2 LWATRWTESPVLNRERYVKLAIREAVTFSVFLALLCVVAYSSRIPLAYEYTHAVSEMFTSSPLSNADPTTFHNLATIEQVWQVFHGYLTGPLLWALHNSGSRNLTN-----SMVSGENLVVEPVIIWQARVHNNSCWSLSTNLGTGTTECYGPYSSANENKDPFGPANSTVWRFDSEAG---VPWQGALGWYGPGGYAVRLPADSRTAAWQELAALRDASWLDRATRLLSVDAALLNPNLRLYMVVRLSMEFPPTGGILTALSLTPGRPLGTPLWDARAV 273
BLAST of PKD2L-1 vs. Ensembl Nematostella
Match: EDO47023 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN85]) HSP 1 Score: 293.893 bits (751), Expect = 5.061e-87 Identity = 211/445 (47.42%), Postives = 302/445 (67.87%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREI--ISEQSEI-PNSESKKTF-----------------IHG-----------------VSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTIL--SSKEHLSEEERKV-KIGNMVQEELIKLNQDAVLTQ 2227 YFKS WN+LDVVVI + ++ ++FN+YRT+AV +L SLL + +Q+ NFD L ++Q FN ++A+ VF AW+K+FKYISFNKTMTQLSSTL +C+KD+AGFA+MFFIIFFA+AQLGYL+FGT++ F SIFTL+RIILGDF F NA+ + GPL+F+ YVFFV FVL NMFLAIINDTY+E+K+++ +Q++EFEI DYFK+ Q ML KL+ K++K+ +Q AL +AD N D +DF+EW+ ++ +G EIE+VF++YD DG+R+LD +EQ MQ LE QK +N EI + Q E P S S+ +F + G VS +E+ L+ R++ ME+ I ++V KI+ VL LE M+ +K KRR++M K+L + S + SE+E+K ++ MV+EEL + + +A +++ Sbjct: 398 YFKSFWNVLDVVVIMLGYVAVVFNLYRTMAVGDLLSSLLEDGSQYANFDSLGFWQTQFNNMVAVAVFFAWIKVFKYISFNKTMTQLSSTLSKCAKDVAGFAIMFFIIFFAYAQLGYLIFGTQVRDFSTFEDSIFTLFRIILGDFDFHQIENANRVLGPLFFMTYVFFVFFVLLNMFLAIINDTYAEVKSDIASQESEFEITDYFKKGYQNMLNKLSFKREKILDIQKALKSADVNQDNKLDFEEWRANLKSRGHADAEIEAVFAKYDLDGDRILDEDEQRRMQEDLEGQKAELNDEIEEMERQKESRPKSASRMSFRGSDADSDDDDDDSQGGLSGRVGSAAGHRRGGGGGGGVSYEEFNVLSRRVDRMEHSIGSIVSKIDAVLVKLEAMEKAKLKRRETMAKLLDSITESDRSGRSEDEKKREQMERMVREELERWDSEASMSR 842 HSP 2 Score: 258.84 bits (660), Expect = 3.344e-74 Identity = 129/298 (43.29%), Postives = 191/298 (64.09%), Query Frame = 3 Query: 63 DEISHADSVSFD----NDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNV--DQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 + +SH ++ D KN V G W RF +R +W T+QTED ++R ++I+TTLREL IY+VF+ IL I+ FGMT+ TMY+ T ++ +LFV ++N +F + + +FW + L +GLYW +YNN NV + ++ FIYFENK++G R RQ+RV + SC + ++F+ +IK CY YS +E FG N +AWTY + +L G ++TY GGG+ L + ++ +L NLW+DRGTRAV +DFTVYNANINLFC+++L+ E+P GG IP ++F+TV Sbjct: 60 EPVSHQKRIAADVRVPGAKN-VPVGCWTRFKRIIRGLWRTRQTEDTDSDREMHIKTTLRELIIYLVFITILCILTFGMTSSTMYYFTKVMRDLFVESSMSNRNTFKDITTMNEFWMYTTETLSDGLYWEQYYNNQNVTKPKDDLGFIYFENKILGRPRFRQLRVLNDSCTVHDDFKSVIKECYAAYSPNVEDMNTFGKMNGSAWTYQTEKDLQGRSYWGRMTTYSGGGFTQLLAPTKAETQQIIEDLKQNLWLDRGTRAVFIDFTVYNANINLFCIVRLVFEYPPTGGCIPSFNFRTV 356
BLAST of PKD2L-1 vs. Ensembl Nematostella
Match: EDO40051 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8E5]) HSP 1 Score: 103.605 bits (257), Expect = 2.908e-23 Identity = 70/245 (28.57%), Postives = 121/245 (49.39%), Query Frame = 3 Query: 210 IQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENK----LIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTE---PFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXX----WIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGV 911 + + +RE+ Y++FL I++ I++G +TN + N+F+ N + F+ + S+ D+W + + ++ ++ WYN+ + + Y + ++ +ARLRQ+R+ +C + Q +I C YS+ E P + TAW Y L + P G +TY GGY P + L + L W+D+ TRAV +F++YNAN NLFCV+ L+ E GG+ Sbjct: 5 MASIMREIVWYLIFLFIVLSISYGNRDPYTQLVTNNVENVFLQASYNGSTKFDEIGSTRDYWPWLKDTVIPSIFIEKWYND-----QDYHLGYLADTPTAWVLAVARLRQLRMQKHTCPLLPALQHVIPSCNDFYSSDEEERGMLLPGWKEPKTAWQYQTGEELKTFPYWGQKATYSAGGYVQVFPPSTAKNYDKAQALADALNENDWLDKYTRAVFTEFSIYNANSNLFCVVTLLIEQLPTGGI 244 HSP 2 Score: 82.4185 bits (202), Expect = 1.725e-16 Identity = 59/201 (29.35%), Postives = 115/201 (57.21%), Query Frame = 2 Query: 1019 KSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDY 1621 K+ W+IL++ V +S ++ R +++ + + + + Y ++ L+ + VF +++KI + + FN+ M+ L+ TL C + F +++ I FFA+AQL L+FG GF + S TL +LG FT ++ + + + GP +F +Y ++F+L NMF++IIND+++E+ +++ Q N++EI D+ Sbjct: 297 KNPWSILEIFVTCLSLSMVVLYFLRIKFTAEVVKDMRNDPTRFVSLHYTAFLDEWIKCLMGLIVFFSFIKIVRLLRFNRRMSLLAQTLKLCIPKIGAFVIVYGIAFFAYAQLACLVFGQNAEGFMTIPRSAATLMDTLLGKFTLKEMSDINRLIGPTFFYIYTLSMIFILINMFMSIINDSFAEVNSDVSKQANDYEIVDF 497
BLAST of PKD2L-1 vs. Ensembl Nematostella
Match: EDO39106 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB30]) HSP 1 Score: 80.4925 bits (197), Expect = 1.398e-21 Identity = 68/195 (34.87%), Postives = 97/195 (49.74%), Query Frame = 3 Query: 363 FNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENK---LIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 F ++ D T+ G LL GLY WYN L SE N Y +K L+GL+RL+Q RV C I E + CY +YS E T L +T + T L +LP G + YGGGG+ +L + A ++N+L + W DR TRAV+ F+V+NAN + + +AE G + P + T+ Sbjct: 2 FFQISKKTDLITWLNGSLLAGLYPAPWYNGL----SESNTAYIGDKCSILLGLSRLKQSRVQTGHCTIPKEVRLRFSTCYASYSHSREDTTLANLPGWKPFTPSPLT-LATLPYWGQKAVYGGGGFVANLGYSESVARRVINDLARDGWFDRQTRAVLAIFSVFNANTDYVSFVNFLAEALTTGTIRPSHRITTI 191 HSP 2 Score: 41.5874 bits (96), Expect = 1.398e-21 Identity = 53/193 (27.46%), Postives = 97/193 (50.26%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFT-LYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNEL 1585 YFK +WN L++++I S + + + I+ + N +FDY+ L+A VF + +K+ K + + + +SST+ L F+ +F +I A+AQLG L+FGT T + ++ ++ T L I GD + + + P Y + ++ F+ F+L N+F+AI+N+ + K L Sbjct: 228 PYFKDIWNWLEMLIILFSVATTAVQFVKGIYLTDIVTKIRSNPYGDFSFDYIVMGTELEESLMACLVFFSSLKLMKLVLLHVRVVVISSTMRVSFIRLLPFSFIFIVILLAYAQLGILVFGTMETSYATVYNALVTELMLFIGGDTRINELREVNRVMAPFYVISFMVFMGFILMNVFVAILNEAQFQQKTSL 420
BLAST of PKD2L-1 vs. Ensembl Nematostella
Match: EDO44884 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUD7]) HSP 1 Score: 97.0561 bits (240), Expect = 1.160e-20 Identity = 69/169 (40.83%), Postives = 102/169 (60.36%), Query Frame = 2 Query: 1133 NDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQ 1639 N N + NF Y+S +Q +F +L I VF++ +K K + FNK M L+ TL R +KDLA + +MF I+F +FAQ YLL G+ F SI L ++LG F+F++FL I G F LY+ F+L NMF+AII ++++E+K +NEFEI ++ ER + Sbjct: 888 NPNDYTNFQYISAWQMSFESILGILVFISTIKFIKLLRFNKKMFLLAYTLSRSAKDLAHYGIMFLIVFLSFAQFYYLLLGSDYDSFSTFVKSIEKLINVLLGRFSFEEFLIPFRIMGAFGFFLYMTLTNFLLLNMFIAIIVESFTEVKLSPELARNEFEIMEFTVERVR 1056 HSP 2 Score: 81.6481 bits (200), Expect = 7.567e-16 Identity = 71/266 (26.69%), Postives = 118/266 (44.36%), Query Frame = 3 Query: 165 ATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNN------TGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYS--TQIEST-----EPFGLQN-----STAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGG 908 A ++ D + ++ + L ++ Y+ FL +L++IA YW + ++++ + + T +F +++ ++ W + LL LY WY + ++G AR RQ+R +C+I + +I C YS TQ E+ PF + ST W++ + L P G ISTY GGGY V S + A + + NN WIDR T + +FT+YN NLF ++ E GG Sbjct: 534 ALEKARD-RNDKERKMSVILTDIGTYLTFLWVLLVIAHSRVDSAAYWQSRSISDVLMKTTYESPPESGLTKTFQKISNDSEIWLWTNHVLLPALYNLDWYYYTKTAPKLVR--GGAGLVVGFARWRQLRKKKDTCLITGVMRGVIHHCTDPYSMSTQDETNYNSRWRPFNTSDVPPSPSTIWSFNSASKLNGYPYFGEISTYSGGGYIVPFSSIYYKAVKEIKHARNNSWIDRYTAGLFTEFTLYNPYSNLFTASTVLVEVLPTGG 796
BLAST of PKD2L-1 vs. Ensembl Nematostella
Match: EDO44744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUR6]) HSP 1 Score: 95.1301 bits (235), Expect = 4.335e-20 Identity = 73/252 (28.97%), Postives = 122/252 (48.41%), Query Frame = 3 Query: 222 LRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFN-------SMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENK-LIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPF---GLQNST--------AWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPL 920 ++E+ Y +F+ +++++A+G + + L ++F +G+ + S ++ FW + + L+ GLY SWYN + + F+ ++G AR+RQ+RV C + + + + +C YS E T P G + + AW Y + L SLP G ++ Y GGGY DL + A ++L L + W+DR TRA+ V+FTVY+ NL CV L+ E GG P Sbjct: 611 IQEILFYALFVWVVLVVAYGHRDPNAHVMNQGLEDVF-SGRAKHDHSVPDGHSLLFQVSDITSFWNWTEAVLIPGLYSESWYNGRS---DKPGFLADHTSWMLGTARMRQLRVKAGDCKVHDVYSGYLAQCNGPYSWDTEDTTPVFRPGWRPAPSNYSTAQNAWKYRDSSELRSLPYLGKLALYSGGGYAFDLGKKE-KAMAMLAQLKRDKWVDRSTRAIFVEFTVYSPYTNLHCVGYLLLEVLPSGGTSPF 857 HSP 2 Score: 73.9442 bits (180), Expect = 1.790e-13 Identity = 54/161 (33.54%), Postives = 92/161 (57.14%), Query Frame = 2 Query: 1151 NFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKER 1633 NF L+ F Y+ A F +K + FNK M+ L++TL +K+LA F+++F ++F AF YL+F T+L F + ++ TL ++LG F+++ L + + P F Y V+F+L NMF++II + + +K++ Q NE+EI D+ E+ Sbjct: 952 NFHALAASDQVFGYVYAFVAFFVSLKFLRLFRFNKRMSLLATTLKCSAKELAHFSIVFGLVFMAFVHFCYLIFSTELYIFHTVLSTVETLISVMLGKFSYERLLQTNRLLAPFMFFFYSIVVVFILINMFISIIIENFQRVKSQNDLQSNEYEIVDFMTEQ 1112
BLAST of PKD2L-1 vs. Ensembl Medaka
Match: pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel [Source:NCBI gene;Acc:100820724]) HSP 1 Score: 228.794 bits (582), Expect = 3.250e-117 Identity = 155/298 (52.01%), Postives = 211/298 (70.81%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREI 1903 SY KSVWNILD+VVI ++ + I FN++RT+ V +L LL N N + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLS+TLGRC+KD+ GFAVMFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF F A+ + GP+YF+ YVFFV FVL NMFLAIINDTYSE+K EL +QK+E +I D K+ +L LKKDK+ +Q AL G + F ++K + E G EI + FS++D DGN+VLDA EQ M+ +L+ ++ A++ E+ Sbjct: 389 SYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQAG----SGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTEL 682 HSP 2 Score: 214.542 bits (545), Expect = 3.250e-117 Identity = 115/263 (43.73%), Postives = 170/263 (64.64%), Query Frame = 3 Query: 150 MRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 ++ +W T TE++ NR YI+TTLREL +Y++FL + ++ +GMT+ + Y+ T + +LFVN + +F S+ + ADFW+FAQGPLL+GLYW WYN +++ +FIY+EN L+G+ R+RQ+++ + SC + +F+ I CY Y + E FGL N TAWTY + + G +STY G GYY DL + + +L+ L +N W+ RGTR V +DF+ YNANIN+FCVI L+ EFPA GG +P Y +TV Sbjct: 86 IKGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSGGDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTV 348
BLAST of PKD2L-1 vs. Ensembl Medaka
Match: pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel [Source:NCBI gene;Acc:100820724]) HSP 1 Score: 229.18 bits (583), Expect = 4.238e-117 Identity = 155/298 (52.01%), Postives = 211/298 (70.81%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREI 1903 SY KSVWNILD+VVI ++ + I FN++RT+ V +L LL N N + +F++L+++Q +N + A+ +F AW+KIFKYISFNKTMTQLS+TLGRC+KD+ GFAVMFFI+FFA+AQLGYLLFGT++ F IFT +RIILGDF F A+ + GP+YF+ YVFFV FVL NMFLAIINDTYSE+K EL +QK+E +I D K+ +L LKKDK+ +Q AL G + F ++K + E G EI + FS++D DGN+VLDA EQ M+ +L+ ++ A++ E+ Sbjct: 389 SYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQAG----SGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTEL 682 HSP 2 Score: 213.772 bits (543), Expect = 4.238e-117 Identity = 115/263 (43.73%), Postives = 170/263 (64.64%), Query Frame = 3 Query: 150 MRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 ++ +W T TE++ NR YI+TTLREL +Y++FL + ++ +GMT+ + Y+ T + +LFVN + +F S+ + ADFW+FAQGPLL+GLYW WYN +++ +FIY+EN L+G+ R+RQ+++ + SC + +F+ I CY Y + E FGL N TAWTY + + G +STY G GYY DL + + +L+ L +N W+ RGTR V +DF+ YNANIN+FCVI L+ EFPA GG +P Y +TV Sbjct: 86 IKGLWGTALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSGGDAGVAFQSIGTMADFWSFAQGPLLDGLYWTKWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTV 348
BLAST of PKD2L-1 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346]) HSP 1 Score: 217.624 bits (553), Expect = 1.876e-59 Identity = 113/274 (41.24%), Postives = 172/274 (62.77%), Query Frame = 3 Query: 123 GFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN--NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G R +R +W T+ ED +NR Y+ LREL YI FL + I+ +GM + MY+ T ++ LF++ ++ N +F S+++ DFW + QGP L G+YW WYNN ++ ++ +FIY+EN L+G+ RLRQVRV +++C I + + ++ CY Y+ E PFG QN TAW +T ++ + + G +S YGGGGYY DL + + L L ++LW+DRGTRA+ +DF+VYN N+NL C+ +L+ EFPA GGV+ + F+TV Sbjct: 130 GCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQ-SFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTV 402 HSP 2 Score: 139.043 bits (349), Expect = 2.095e-33 Identity = 139/435 (31.95%), Postives = 233/435 (53.56%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLN-ADIIFG--PXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIH-------------------------GVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEE--RKVKIGNMVQEELIKLNQDAVLTQ 2227 YFK++WN LDV+++ +S + II +I R +L+ L N H +FD L+ Q FN + A+ VF WVK+FK+I+FNKTM+QLS+T+ RC+KDL GFA+MFFIIF A+AQL YL+FGT++ F TFQ ++ D+++ PL+FL ++F +K ++ ++E E+ D+ K+ L KL LKK +D + ++L A G +++DE ++EKG EI+++F++YD DG+ L ++ +M++ LE ++ ++ E++ + S ++F GVS +E+Q L R++ ME+ I ++V KI+ V+ LE M+ +K KRR + ++L + E L + + ++ +V+EEL + D V +Q Sbjct: 444 YFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKGL-ENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFS-----------------TFQGSVSRTDLLYNLRPLHFLYSHGEKGICTVSLF----------VKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQAG----GKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKER----EDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELERWETDDVASQ 842
BLAST of PKD2L-1 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346]) HSP 1 Score: 217.624 bits (553), Expect = 2.824e-59 Identity = 113/274 (41.24%), Postives = 172/274 (62.77%), Query Frame = 3 Query: 123 GFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN--NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G R +R +W T+ ED +NR Y+ LREL YI FL + I+ +GM + MY+ T ++ LF++ ++ N +F S+++ DFW + QGP L G+YW WYNN ++ ++ +FIY+EN L+G+ RLRQVRV +++C I + + ++ CY Y+ E PFG QN TAW +T ++ + + G +S YGGGGYY DL + + L L ++LW+DRGTRA+ +DF+VYN N+NL C+ +L+ EFPA GGV+ + F+TV Sbjct: 130 GCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQ-SFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTV 402 HSP 2 Score: 203.371 bits (516), Expect = 1.708e-54 Identity = 163/432 (37.73%), Postives = 259/432 (59.95%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIH-------------------------GVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEE--RKVKIGNMVQEELIKLNQDAVLTQ 2227 YFK++WN LDV+++ +S + II +I R +L+ L N H +FD L+ Q FN + A+ VF WVK+FK+I+FNKTM+QLS+T+ RC+KDL GFA+MFFIIF A+AQL YL+FGT++ F S+FT +RIILGDF F + A+ + GP+YF+ +V F+ F+L NMFLAIINDTYSE+K ++ ++E E+ D+ K+ L KL LKK +D + ++L A G +++DE ++EKG EI+++F++YD DG+ L ++ +M++ LE ++ ++ E++ + S ++F GVS +E+Q L R++ ME+ I ++V KI+ V+ LE M+ +K KRR + ++L + E L + + ++ +V+EEL + D V +Q Sbjct: 444 YFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKGL-ENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKER----EDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELERWETDDVASQ 866
BLAST of PKD2L-1 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346]) HSP 1 Score: 218.009 bits (554), Expect = 3.074e-59 Identity = 113/274 (41.24%), Postives = 172/274 (62.77%), Query Frame = 3 Query: 123 GFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN--NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 G R +R +W T+ ED +NR Y+ LREL YI FL + I+ +GM + MY+ T ++ LF++ ++ N +F S+++ DFW + QGP L G+YW WYNN ++ ++ +FIY+EN L+G+ RLRQVRV +++C I + + ++ CY Y+ E PFG QN TAW +T ++ + + G +S YGGGGYY DL + + L L ++LW+DRGTRA+ +DF+VYN N+NL C+ +L+ EFPA GGV+ + F+TV Sbjct: 130 GCMKRIFQNIRILWGTELMEDGDSNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPKTFRSLSTMEDFWKYTQGPFLGGMYWEVWYNNQSLPGNQ-SFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGPQNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTV 402 HSP 2 Score: 202.986 bits (515), Expect = 3.879e-54 Identity = 164/444 (36.94%), Postives = 262/444 (59.01%), Query Frame = 2 Query: 1013 YFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIH-------------------------GVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEE--RKVKIGNMVQEELIKLNQDAVLTQKRKQNFKSDFEQ 2263 YFK++WN LDV+++ +S + II +I R +L+ L N H +FD L+ Q FN + A+ VF WVK+FK+I+FNKTM+QLS+T+ RC+KDL GFA+MFFIIF A+AQL YL+FGT++ F S+FT +RIILGDF F + A+ + GP+YF+ +V F+ F+L NMFLAIINDTYSE+K ++ ++E E+ D+ K+ L KL LKK +D + ++L A G +++DE ++EKG EI+++F++YD DG+ L ++ +M++ LE ++ ++ E++ + S ++F GVS +E+Q L R++ ME+ I ++V KI+ V+ LE M+ +K KRR + ++L + E L + + ++ +V+EEL + D V +Q + D + Sbjct: 444 YFKNLWNCLDVLIVTLSVVAIIMSITRAAMGGDLLKGL-ENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQA----GGKLNYDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDL----ERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLDGVMEDERLGRDADTHREQMERLVKEELERWETDDVASQSAMRILPEDIHK 878
BLAST of PKD2L-1 vs. Planmine SMEST
Match: SMESG000018514.1 (SMESG000018514.1) HSP 1 Score: 599.356 bits (1544), Expect = 0.000e+0 Identity = 310/311 (99.68%), Postives = 310/311 (99.68%), Query Frame = 3 Query: 6 MAKGWSTEDMKANVEYDAYDEISHADSVSFDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 MAKGWSTEDMKANVEYDAYDEISHADSVSFDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLREL IYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTYGGGGYYVDLPSDQFSAFSLLNNLFNNLWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV Sbjct: 1 MAKGWSTEDMKANVEYDAYDEISHADSVSFDNDKNKVKYGFWNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELVIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVNNTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTYGGGGYYVDLPSDQFSAFSLLNNLFNNLWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 311 HSP 2 Score: 218.779 bits (556), Expect = 0.000e+0 Identity = 133/134 (99.25%), Postives = 134/134 (100.00%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSI 1411 SYFKSVWNILDVVVIGISFICIIFNIYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFGTKLTGFRELHYS+ Sbjct: 352 SYFKSVWNILDVVVIGISFICIIFNIYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMFFIIFFAFAQLGYLLFGTKLTGFRELHYSM 485
BLAST of PKD2L-1 vs. Planmine SMEST
Match: SMESG000018504.1 (SMESG000018504.1) HSP 1 Score: 308.531 bits (789), Expect = 7.493e-160 Identity = 163/306 (53.27%), Postives = 217/306 (70.92%), Query Frame = 3 Query: 54 DAYDEISHA-DSVSFDNDKNKV----KYGF-----WNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN-NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 D++D A D FDN K + + GF WN+F G+RS+WATK TE+ ++NLY TT+REL +Y++FL +L II F M G M++ TN LNNLF+ Q N N+G+F+S+ + +DFW F GPLLNGLYWN WYN+ N+ +E N+IYFENKL+G+ R+RQ+RV + SCII N Q + +CY YS IE E FG QNS+AW YT + L S QG I+TYGGGG+YVDL + Q ++ +++ +LFNN W+DR TRAV+VDFT+YNANINLFC+IKL+ EFP VGGV+P Y+F+TV Sbjct: 16 DSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTV 321 HSP 2 Score: 276.559 bits (706), Expect = 7.493e-160 Identity = 192/405 (47.41%), Postives = 275/405 (67.90%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISE---QSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDA 2215 +YF S+WN+LDV+V+ + IC+ F+IYR +QT+L LL N N HPNF+YLS++Q ++ L A +FLA KIFKYISFNK MTQL STL C KDL GF++MFFI+F AFAQ GYL+FG++L +RE + IFTL+RIIL D F++ L + I GPLYF+LYVFFV F+LFNMFLAI++D Y D+ KE+++ + KL+LK++K+ L+NA+ DTNNDG+MDFDEWKT ++ +G+ EIES+F+++DTDG+RVLD EQ++M +L +QKTA+ E+I E Q ++ S++ I +S +Y L+ I+++EN+I L K + +L + +N+ +K K R+S IL S SE+ RK KI ++Q+EL KLN++ Sbjct: 362 AYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDA----IQPISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRET 745
BLAST of PKD2L-1 vs. Planmine SMEST
Match: SMESG000018504.1 (SMESG000018504.1) HSP 1 Score: 308.531 bits (789), Expect = 8.419e-160 Identity = 163/306 (53.27%), Postives = 217/306 (70.92%), Query Frame = 3 Query: 54 DAYDEISHA-DSVSFDNDKNKV----KYGF-----WNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN-NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 D++D A D FDN K + + GF WN+F G+RS+WATK TE+ ++NLY TT+REL +Y++FL +L II F M G M++ TN LNNLF+ Q N N+G+F+S+ + +DFW F GPLLNGLYWN WYN+ N+ +E N+IYFENKL+G+ R+RQ+RV + SCII N Q + +CY YS IE E FG QNS+AW YT + L S QG I+TYGGGG+YVDL + Q ++ +++ +LFNN W+DR TRAV+VDFT+YNANINLFC+IKL+ EFP VGGV+P Y+F+TV Sbjct: 27 DSHDNAPCAMDGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTV 332 HSP 2 Score: 276.174 bits (705), Expect = 8.419e-160 Identity = 192/405 (47.41%), Postives = 275/405 (67.90%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISE---QSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDA 2215 +YF S+WN+LDV+V+ + IC+ F+IYR +QT+L LL N N HPNF+YLS++Q ++ L A +FLA KIFKYISFNK MTQL STL C KDL GF++MFFI+F AFAQ GYL+FG++L +RE + IFTL+RIIL D F++ L + I GPLYF+LYVFFV F+LFNMFLAI++D Y D+ KE+++ + KL+LK++K+ L+NA+ DTNNDG+MDFDEWKT ++ +G+ EIES+F+++DTDG+RVLD EQ++M +L +QKTA+ E+I E Q ++ S++ I +S +Y L+ I+++EN+I L K + +L + +N+ +K K R+S IL S SE+ RK KI ++Q+EL KLN++ Sbjct: 373 AYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDA----IQPISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRET 756
BLAST of PKD2L-1 vs. Planmine SMEST
Match: SMESG000018504.1 (SMESG000018504.1) HSP 1 Score: 307.375 bits (786), Expect = 1.287e-159 Identity = 160/296 (54.05%), Postives = 212/296 (71.62%), Query Frame = 3 Query: 81 DSVSFDNDKNKV----KYGF-----WNRFSNGMRSIWATKQTEDIKANRNLYIQTTLRELFIYIVFLAILMIIAFGMTTGTMYWLTNLLNNLFVNGQVN-NTGSFNSMASSADFWTFAQGPLLNGLYWNSWYNNLNVDQSEINFIYFENKLIGLARLRQVRVSDKSCIIANEFQKIIKRCYVTYSTQIESTEPFGLQNSTAWTYTRQTNLGSLPIQGSISTXXXXXXXVDLPSDQFSAFSXXXXXXXXXWIDRGTRAVIVDFTVYNANINLFCVIKLIAEFPAVGGVIPLYDFKTV 938 D FDN K + + GF WN+F G+RS+WATK TE+ ++NLY TT+REL +Y++FL +L II F M G M++ TN LNNLF+ Q N N+G+F+S+ + +DFW F GPLLNGLYWN WYN+ N+ +E N+IYFENKL+G+ R+RQ+RV + SCII N Q + +CY YS IE E FG QNS+AW YT + L S QG I+TYGGGG+YVDL + Q ++ +++ +LFNN W+DR TRAV+VDFT+YNANINLFC+IKL+ EFP VGGV+P Y+F+TV Sbjct: 2 DGEYFDNGKITIIDYQEIGFKNENCWNKFKIGIRSLWATKHTENCDEDKNLYANTTVRELVVYMLFLVLLFIITFSMRPGYMFYFTNFLNNLFLTTQFNDNSGTFSSLQAQSDFWKFLMGPLLNGLYWNVWYNSRNMPANEQNYIYFENKLLGVPRIRQIRVKNNSCIIPNILQNKVNQCYAAYSRNIELKESFGFQNSSAWNYTEDSILQSGSFQGQITTYGGGGFYVDLATSQENSLNIILSLFNNRWLDRNTRAVLVDFTIYNANINLFCIIKLVGEFPPVGGVLPSYEFRTV 297 HSP 2 Score: 276.944 bits (707), Expect = 1.287e-159 Identity = 192/405 (47.41%), Postives = 275/405 (67.90%), Query Frame = 2 Query: 1010 SYFKSVWNILDXXXXXXXXXXXXXXXYRTVAVQTILESLLMNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTLGRCSKDLAGFAVMXXXXXXXXXQLGYLLFGTKLTGFRELHYSIFTLYRIILGDFTFQDFLNADIIFGPXXXXXXXXXXXXXXXNMFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISE---QSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDA 2215 +YF S+WN+LDV+V+ + IC+ F+IYR +QT+L LL N N HPNF+YLS++Q ++ L A +FLA KIFKYISFNK MTQL STL C KDL GF++MFFI+F AFAQ GYL+FG++L +RE + IFTL+RIIL D F++ L + I GPLYF+LYVFFV F+LFNMFLAI++D Y D+ KE+++ + KL+LK++K+ L+NA+ DTNNDG+MDFDEWKT ++ +G+ EIES+F+++DTDG+RVLD EQ++M +L +QKTA+ E+I E Q ++ S++ I +S +Y L+ I+++EN+I L K + +L + +N+ +K K R+S IL S SE+ RK KI ++Q+EL KLN++ Sbjct: 338 AYFCSLWNVLDVIVLSLGVICVSFHIYRMYMIQTMLSKLLENGNIHPNFEYLSFWQLQYDNLSAFLLFLAITKIFKYISFNKMMTQLISTLNYCLKDLVGFSLMFFIVFLAFAQAGYLIFGSQLANYREFYICIFTLFRIILNDCNFKELLPLNPILGPLYFILYVFFVFFILFNMFLAILDDAY-----------------DFLKEKSRKVFEKLHLKREKIVDLENAMKTVDTNNDGVMDFDEWKTELKRRGYAETEIESLFAKFDTDGDRVLDEQEQLKMLKELNDQKTALETELIEERDNQEKLIESDA----IQPISYAKYMGLSRHIDDLENIIEILTQKFDIILDNFQNIIKTKEKSRESTEIILNAFSMMVENSEDYRKEKIEAIIQDELYKLNRET 721
BLAST of PKD2L-1 vs. Planmine SMEST
Match: SMESG000018510.1 (SMESG000018510.1) HSP 1 Score: 424.476 bits (1090), Expect = 1.216e-144 Identity = 242/244 (99.18%), Postives = 244/244 (100.00%), Query Frame = 2 Query: 1535 MFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMXXXXXXXXXXXXXXQNALTNADTNNDGLMDFDEWKTAMQEKGFESYEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDXXXXXXXXXXXXILTILSSKEHLSEEERKVKIGNMVQEELIKLNQDAVLTQKRKQNFKSDFEQN 2266 MFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMLAKLNLKKDKLDVLQNALTNADTNNDGLMDFDEWKTAMQEKGFES+EIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDNSKNKRRKSMRKILTILSSKEHLSEEERKVKIGNMVQ+ELIKLNQDAVLTQKRKQNFKSDFEQN Sbjct: 1 MFLAIINDTYSEIKNELINQKNEFEIGDYFKERTQMMLAKLNLKKDKLDVLQNALTNADTNNDGLMDFDEWKTAMQEKGFESHEIESVFSRYDTDGNRVLDANEQIEMQNQLENQKTAVNREIISEQSEIPNSESKKTFIHGVSIDEYQDLNFRIEEMENVINTLVLKINDVLKDLENMDNSKNKRRKSMRKILTILSSKEHLSEEERKVKIGNMVQKELIKLNQDAVLTQKRKQNFKSDFEQN 244 The following BLAST results are available for this feature:
BLAST of PKD2L-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of PKD2L-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of PKD2L-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of PKD2L-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of PKD2L-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of PKD2L-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of PKD2L-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of PKD2L-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of PKD2L-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 4
BLAST of PKD2L-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of PKD2L-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of PKD2L-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of PKD2L-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of PKD2L-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014978 ID=SMED30014978|Name=PKD2L-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2337bpback to top protein sequence of SMED30014978-orf-1 >SMED30014978-orf-1 ID=SMED30014978-orf-1|Name=SMED30014978-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=380bp MNDNQHPNFDYLSYYQFTFNYLLAITVFLAWVKIFKYISFNKTMTQLSSTback to top protein sequence of SMED30014978-orf-2 >SMED30014978-orf-2 ID=SMED30014978-orf-2|Name=SMED30014978-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=328bp KMAKGWSTEDMKANVEYDAYDEISHADSVSFDNDKNKVKYGFWNRFSNGMback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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