Gelsolin

Overview
NameGelsolin
Smed IDSMED30014940
Length (bp)530
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Expression Details

Click to see image symbols and abbreviations
Abbreviation or symbolDefinition
Ooral hemisphere
Aaboral hemisphere
Ddorsal
Vventral
Llateral
black arrowheadembryonic pharynx
red arrowheaddefinitive pharynx
black arrowsprimitive gut
yellow arrowsprimitive ectoderm cells
cyan arrowsbrain
cyan arrowheadsnerve cords
blue arrowheadseye progenitors (trail cells)
purple arrowheadseyes
scale bar100 µm
Anatomical Expression

PAGE et. al., 2020



SMED30014940

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
embryonic pharynxSMED30014940SMESG000035418.1 SMED30014940smed_20140614PMID:28072387
Davies et al., 2017		whole organism Stage 3 colorimetric in situ hybridization evidence
embryonic pharynxSMED30014940SMESG000035418.1 SMED30014940smed_20140614PMID:28072387
Davies et al., 2017		whole organism Stage 4 colorimetric in situ hybridization evidence
embryonic pharynxSMED30014940SMESG000035418.1 SMED30014940smed_20140614PMID:28072387
Davies et al., 2017		whole organism Stage 5 colorimetric in situ hybridization evidence
embryonic pharynxSMED30014940SMESG000035418.1 SMED30014940smed_20140614PMID:28072387
Davies et al., 2017		whole organism Stage 2 colorimetric in situ hybridization evidence
primitive ectodermSMED30014940SMESG000035418.1 SMED30014940smed_20140614PMID:28072387
Davies et al., 2017		whole organism Stage 5 colorimetric in situ hybridization evidence
primitive ectodermSMED30014940SMESG000035418.1 SMED30014940smed_20140614PMID:28072387
Davies et al., 2017		whole organism Stage 2 colorimetric in situ hybridization evidence
primitive ectodermSMED30014940SMESG000035418.1 SMED30014940smed_20140614PMID:28072387
Davies et al., 2017		whole organism Stage 4 colorimetric in situ hybridization evidence
primitive ectodermSMED30014940SMESG000035418.1 SMED30014940smed_20140614PMID:28072387
Davies et al., 2017		whole organism Stage 3 colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Gelsolin vs. Ensembl Human
Match: VIL1 (villin 1 [Source:HGNC Symbol;Acc:HGNC:12690])

HSP 1 Score: 69.3218 bits (168), Expect = 8.852e-15
Identity = 32/76 (42.11%), Postives = 48/76 (63.16%), Query Frame = 3 
Query:  303 VKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            + K SA+ + +  +    T PGL +WRIE  +++ +P   FG F++GD YIIL I+K   S  L YD+H+WIG+ S
Sbjct:    1 MTKLSAQVKGSLNI----TTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASS--LSYDIHYWIGQDS 70
[Close]
BLAST of Gelsolin vs. Ensembl Human
Match: VIL1 (villin 1 [Source:HGNC Symbol;Acc:HGNC:12690])

HSP 1 Score: 69.707 bits (169), Expect = 8.333e-14
Identity = 29/58 (50.00%), Postives = 40/58 (68.97%), Query Frame = 3 
Query:  357 TVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            T PGL +WRIE  +++ +P   FG F++GD YIIL I+K   S  L YD+H+WIG+ S
Sbjct:   15 TTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASS--LSYDIHYWIGQDS 70
[Close]
BLAST of Gelsolin vs. Ensembl Human
Match: VIL1 (villin 1 [Source:HGNC Symbol;Acc:HGNC:12690])

HSP 1 Score: 68.9366 bits (167), Expect = 1.669e-13
Identity = 29/58 (50.00%), Postives = 40/58 (68.97%), Query Frame = 3 
Query:  357 TVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            T PGL +WRIE  +++ +P   FG F++GD YIIL I+K   S  L YD+H+WIG+ S
Sbjct:   15 TTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASS--LSYDIHYWIGQDS 70
[Close]
BLAST of Gelsolin vs. Ensembl Human
Match: GSN (gelsolin [Source:HGNC Symbol;Acc:HGNC:4620])

HSP 1 Score: 60.8474 bits (146), Expect = 5.286e-11
Identity = 25/58 (43.10%), Postives = 39/58 (67.24%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            KA   PGL +WR+EKF ++ +P   +G F+ GD+Y+ILK  +  +   L YD+H+W+G
Sbjct:   10 KAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNG-NLQYDLHYWLG 66
[Close]
BLAST of Gelsolin vs. Ensembl Human
Match: GSN (gelsolin [Source:HGNC Symbol;Acc:HGNC:4620])

HSP 1 Score: 60.4622 bits (145), Expect = 6.102e-11
Identity = 25/58 (43.10%), Postives = 39/58 (67.24%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            KA   PGL +WR+EKF ++ +P   +G F+ GD+Y+ILK  +  +   L YD+H+W+G
Sbjct:   21 KAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNG-NLQYDLHYWLG 77
[Close]
BLAST of Gelsolin vs. Ensembl Celegans
Match: gsnl-1 (Gelsolin-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21253])

HSP 1 Score: 47.7506 bits (112), Expect = 1.347e-6
Identity = 24/53 (45.28%), Postives = 32/53 (60.38%), Query Frame = 3 
Query:  366 GLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGK 524
            GL VWRI KF +  +P+ + G FY GD+YI L    +       +DVHFW+GK
Sbjct:   18 GLLVWRINKFVLEPVPEVDHGVFYIGDAYIALYQKYDG-----CWDVHFWLGK 65
[Close]
BLAST of Gelsolin vs. Ensembl Fly
Match: Gel (gene:FBgn0010225 transcript:FBtr0078973)

HSP 1 Score: 65.4698 bits (158), Expect = 1.303e-12
Identity = 28/59 (47.46%), Postives = 39/59 (66.10%), Query Frame = 3 
Query:  345 AKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            A A   PGL +WRIE F+ +  PK  +GKFY GDS+I+L   + +   +L +DVHFW+G
Sbjct:   64 ANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLG 122
[Close]
BLAST of Gelsolin vs. Ensembl Fly
Match: Gel (gene:FBgn0010225 transcript:FBtr0309256)

HSP 1 Score: 65.4698 bits (158), Expect = 1.303e-12
Identity = 28/59 (47.46%), Postives = 39/59 (66.10%), Query Frame = 3 
Query:  345 AKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            A A   PGL +WRIE F+ +  PK  +GKFY GDS+I+L   + +   +L +DVHFW+G
Sbjct:   64 ANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLG 122
[Close]
BLAST of Gelsolin vs. Ensembl Fly
Match: Gel (gene:FBgn0010225 transcript:FBtr0078969)

HSP 1 Score: 65.4698 bits (158), Expect = 1.303e-12
Identity = 28/59 (47.46%), Postives = 39/59 (66.10%), Query Frame = 3 
Query:  345 AKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            A A   PGL +WRIE F+ +  PK  +GKFY GDS+I+L   + +   +L +DVHFW+G
Sbjct:   64 ANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLG 122
[Close]
BLAST of Gelsolin vs. Ensembl Fly
Match: Gel (gene:FBgn0010225 transcript:FBtr0078968)

HSP 1 Score: 65.4698 bits (158), Expect = 1.303e-12
Identity = 28/59 (47.46%), Postives = 39/59 (66.10%), Query Frame = 3 
Query:  345 AKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            A A   PGL +WRIE F+ +  PK  +GKFY GDS+I+L   + +   +L +DVHFW+G
Sbjct:   64 ANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLG 122
[Close]
BLAST of Gelsolin vs. Ensembl Fly
Match: Gel (gene:FBgn0010225 transcript:FBtr0309257)

HSP 1 Score: 65.4698 bits (158), Expect = 1.389e-12
Identity = 28/59 (47.46%), Postives = 39/59 (66.10%), Query Frame = 3 
Query:  345 AKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            A A   PGL +WRIE F+ +  PK  +GKFY GDS+I+L   + +   +L +DVHFW+G
Sbjct:   52 ANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLG 110
[Close]
BLAST of Gelsolin vs. Ensembl Zebrafish
Match: gsna (gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653])

HSP 1 Score: 70.0922 bits (170), Expect = 4.726e-14
Identity = 30/60 (50.00%), Postives = 43/60 (71.67%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKY 527
            +A   PGL VWRIEKF ++++P+  +G FY GD+Y++LK  K+  S  L YD+HFW+G Y
Sbjct:    9 RAGKEPGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTTKQT-SGNLQYDLHFWLGDY 67
[Close]
BLAST of Gelsolin vs. Ensembl Zebrafish
Match: gsna (gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653])

HSP 1 Score: 70.0922 bits (170), Expect = 4.726e-14
Identity = 30/60 (50.00%), Postives = 43/60 (71.67%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKY 527
            +A   PGL VWRIEKF ++++P+  +G FY GD+Y++LK  K+  S  L YD+HFW+G Y
Sbjct:    9 RAGKEPGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTTKQT-SGNLQYDLHFWLGDY 67
[Close]
BLAST of Gelsolin vs. Ensembl Zebrafish
Match: gsna (gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653])

HSP 1 Score: 69.707 bits (169), Expect = 6.838e-14
Identity = 30/60 (50.00%), Postives = 43/60 (71.67%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKY 527
            +A   PGL VWRIEKF ++++P+  +G FY GD+Y++LK  K+  S  L YD+HFW+G Y
Sbjct:    9 RAGKEPGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTTKQT-SGNLQYDLHFWLGDY 67
[Close]
BLAST of Gelsolin vs. Ensembl Zebrafish
Match: gsna (gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653])

HSP 1 Score: 69.3218 bits (168), Expect = 7.367e-14
Identity = 30/60 (50.00%), Postives = 43/60 (71.67%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKY 527
            +A   PGL VWRIEKF ++++P+  +G FY GD+Y++LK  K+  S  L YD+HFW+G Y
Sbjct:    9 RAGKEPGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTTKQT-SGNLQYDLHFWLGDY 67
[Close]
BLAST of Gelsolin vs. Ensembl Zebrafish
Match: gsna (gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653])

HSP 1 Score: 69.3218 bits (168), Expect = 7.367e-14
Identity = 30/60 (50.00%), Postives = 43/60 (71.67%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKY 527
            +A   PGL VWRIEKF ++++P+  +G FY GD+Y++LK  K+  S  L YD+HFW+G Y
Sbjct:    9 RAGKEPGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTTKQT-SGNLQYDLHFWLGDY 67
[Close]
BLAST of Gelsolin vs. Ensembl Xenopus
Match: ENSXETT00000019805.1 (gelsolin-like [Source:NCBI gene;Acc:108644441])

HSP 1 Score: 67.3958 bits (163), Expect = 1.932e-14
Identity = 27/61 (44.26%), Postives = 43/61 (70.49%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            KA   PGL VWR+EKF ++++P+ ++G F+ GD+Y++L   K   S  L YD+H+W+GK+ 
Sbjct:   10 KAGKAPGLQVWRVEKFDLVAVPQNQYGSFFTGDAYLVLSTIKTR-SGNLQYDLHYWLGKHC 69
[Close]
BLAST of Gelsolin vs. Ensembl Xenopus
Match: vil1 (villin 1 [Source:NCBI gene;Acc:100124960])

HSP 1 Score: 60.4622 bits (145), Expect = 1.401e-10
Identity = 22/58 (37.93%), Postives = 38/58 (65.52%), Query Frame = 3 
Query:  357 TVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            T PGL +WR+E   ++ +P+  +G F++GD Y++L  +K  ++    YD+HFW+G  S
Sbjct:   15 TTPGLQIWRVESMNLVPVPENSYGNFFDGDCYVLLMTHKTGNN--FTYDIHFWVGNDS 70
[Close]
BLAST of Gelsolin vs. Ensembl Xenopus
Match: jazf1 (JAZF zinc finger 1 [Source:Xenbase;Acc:XB-GENE-950886])

HSP 1 Score: 57.7658 bits (138), Expect = 1.180e-9
Identity = 26/57 (45.61%), Postives = 41/57 (71.93%), Query Frame = 3 
Query:  363 PGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPE-LLYDVHFWIGKYS 530
            PGL +W +EK K++ +P++ +G F+ GD YI+L  NK+  +P  L+ D+H+WIGK S
Sbjct:   12 PGLQIWSMEKMKMVPIPEKAYGSFFEGDCYILL-YNKQ--TPNGLISDIHYWIGKDS 65
[Close]
BLAST of Gelsolin vs. Ensembl Xenopus
Match: jazf1 (JAZF zinc finger 1 [Source:Xenbase;Acc:XB-GENE-950886])

HSP 1 Score: 57.7658 bits (138), Expect = 1.320e-9
Identity = 26/57 (45.61%), Postives = 41/57 (71.93%), Query Frame = 3 
Query:  363 PGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPE-LLYDVHFWIGKYS 530
            PGL +W +EK K++ +P++ +G F+ GD YI+L  NK+  +P  L+ D+H+WIGK S
Sbjct:   12 PGLQIWSMEKMKMVPIPEKAYGSFFEGDCYILL-YNKQ--TPNGLISDIHYWIGKDS 65
[Close]
BLAST of Gelsolin vs. Ensembl Xenopus
Match: jazf1 (JAZF zinc finger 1 [Source:Xenbase;Acc:XB-GENE-950886])

HSP 1 Score: 55.4546 bits (132), Expect = 6.700e-9
Identity = 24/57 (42.11%), Postives = 38/57 (66.67%), Query Frame = 3 
Query:  363 PGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPE-LLYDVHFWIGKYS 530
            PGL +W +EK K++ +P++ +G F+ GD YI+L       +P  L+ D+H+WIGK S
Sbjct:   38 PGLQIWSMEKMKMVPIPEKAYGSFFEGDCYILLY------TPNGLISDIHYWIGKDS 88
[Close]
BLAST of Gelsolin vs. Ensembl Mouse
Match: Vil1 (villin 1 [Source:MGI Symbol;Acc:MGI:98930])

HSP 1 Score: 66.6254 bits (161), Expect = 8.242e-13
Identity = 26/58 (44.83%), Postives = 40/58 (68.97%), Query Frame = 3 
Query:  357 TVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            T PG+ +WRIE  +++ +P   FG F++GD Y++L I+K   S  L YD+H+WIG+ S
Sbjct:   15 TTPGIQIWRIEAMQMVPVPSSTFGSFFDGDCYVVLAIHK--TSSTLSYDIHYWIGQDS 70
[Close]
BLAST of Gelsolin vs. Ensembl Mouse
Match: Gsn (gelsolin [Source:MGI Symbol;Acc:MGI:95851])

HSP 1 Score: 60.077 bits (144), Expect = 2.526e-11
Identity = 25/58 (43.10%), Postives = 39/58 (67.24%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            KA   PGL +WR+EKF ++ +P   +G F+ GD+Y+ILK  +  +   L YD+H+W+G
Sbjct:   21 KAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNG-NLQYDLHYWLG 77
[Close]
BLAST of Gelsolin vs. Ensembl Mouse
Match: Gsn (gelsolin [Source:MGI Symbol;Acc:MGI:95851])

HSP 1 Score: 60.4622 bits (145), Expect = 4.277e-11
Identity = 25/58 (43.10%), Postives = 39/58 (67.24%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            KA   PGL +WR+EKF ++ +P   +G F+ GD+Y+ILK  +  +   L YD+H+W+G
Sbjct:   10 KAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNG-NLQYDLHYWLG 66
[Close]
BLAST of Gelsolin vs. Ensembl Mouse
Match: Gsn (gelsolin [Source:MGI Symbol;Acc:MGI:95851])

HSP 1 Score: 60.4622 bits (145), Expect = 4.277e-11
Identity = 25/58 (43.10%), Postives = 39/58 (67.24%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            KA   PGL +WR+EKF ++ +P   +G F+ GD+Y+ILK  +  +   L YD+H+W+G
Sbjct:   10 KAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNG-NLQYDLHYWLG 66
[Close]
BLAST of Gelsolin vs. Ensembl Mouse
Match: Gsn (gelsolin [Source:MGI Symbol;Acc:MGI:95851])

HSP 1 Score: 60.8474 bits (146), Expect = 9.002e-11
Identity = 30/86 (34.88%), Postives = 48/86 (55.81%), Query Frame = 3 
Query:  282 GSDTEKLVKKTSAETEPAWRVA------KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            G   E+  +   +E  P+  V       KA   PGL +WR+EKF ++ +P   +G F+ GD+Y+ILK  +  +   L YD+H+W+G
Sbjct:   31 GRAQERAPQSRVSEARPSTMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNG-NLQYDLHYWLG 115
[Close]
BLAST of Gelsolin vs. UniProt/SwissProt
Match: sp|Q7JQD3|GELS1_LUMTE (Gelsolin-like protein 1 OS=Lumbricus terrestris OX=6398 GN=AM PE=1 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 9.398e-34
Identity = 67/103 (65.05%), Postives = 73/103 (70.87%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINK-EEDSPELLYDVHFWIGKYS 530
            TG+IK K YDWKDSNLALFGSDTEK VKK SA TEPAW+ A      GL +WRI  FKV   P+ + GKFYNGDSYIIL   K +  S EL YDVHFWIG  S
Sbjct:    3 TGLIKAKEYDWKDSNLALFGSDTEKQVKKDSAATEPAWKGAGQKE--GLKIWRIVNFKVTEWPQNQHGKFYNGDSYIILNTYKPDPKSNELAYDVHFWIGSQS 103
[Close]
BLAST of Gelsolin vs. UniProt/SwissProt
Match: sp|Q24800|SEVE_ECHGR (Severin OS=Echinococcus granulosus OX=6210 GN=AG8 PE=2 SV=3)

HSP 1 Score: 117.087 bits (292), Expect = 1.843e-30
Identity = 52/102 (50.98%), Postives = 68/102 (66.67%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
             G++K K+YDWKDSN+ LFGS  ++ VKK SA TE  W      T P L VWR+ +F +  +P +E G FYNGDSY+I K  +     +LLY+VHFWIGK+S
Sbjct:    2 AGLVKAKDYDWKDSNMELFGSSKDRQVKKESAMTEKCWEPVGRATSPFLMVWRVNQFTLEPVPSDEIGNFYNGDSYVICKATRSPGGDKLLYNVHFWIGKHS 103
[Close]
BLAST of Gelsolin vs. UniProt/SwissProt
Match: sp|Q8MPM1|GELS2_LUMTE (Gelsolin-like protein 2 OS=Lumbricus terrestris OX=6398 GN=gelsolin PE=1 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 1.532e-26
Identity = 54/102 (52.94%), Postives = 68/102 (66.67%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            +G++K K YDWKDSNLA+FGS  +K VKK SA  E AW+        GL +WRI  FKV   P++++G F++GDSYIIL   K +   EL YDVHFWIG  S
Sbjct:    2 SGLVKAKRYDWKDSNLAMFGSALDKSVKKESALKEAAWKGVGEKV--GLKIWRIVNFKVTEWPEKDYGSFFSGDSYIILNTYKLKGREELAYDVHFWIGSKS 101
[Close]
BLAST of Gelsolin vs. UniProt/SwissProt
Match: sp|P10733|SEVE_DICDI (Severin OS=Dictyostelium discoideum OX=44689 GN=sevA PE=1 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 4.010e-20
Identity = 45/101 (44.55%), Postives = 67/101 (66.34%), Query Frame = 3 
Query:  231 MIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWR-VAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            MIK +  D   +N+A  G+D +K  +  +A TE  W+ V +A   PGL +WRIE FKV+ +P+  +GKFY+GDSYIIL   KE +S  L +D+HF++G ++
Sbjct:    1 MIKNRKLDITSTNVAGIGTDLDKKCRLDAASTEAQWKGVGQA---PGLKIWRIENFKVVPVPESSYGKFYDGDSYIILHTFKEGNS--LKHDIHFFLGTFT 96
[Close]
BLAST of Gelsolin vs. UniProt/SwissProt
Match: sp|Q10L71|VLN2_ORYSJ (Villin-2 OS=Oryza sativa subsp. japonica OX=39947 GN=VLN2 PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.891e-14
Identity = 30/56 (53.57%), Postives = 40/56 (71.43%), Query Frame = 3 
Query:  363 PGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            PG  +WRI+ FK + LPK ++GKFYNGDSYI+L+    +     L+D+HFWIGK S
Sbjct:   19 PGTEIWRIQDFKPVPLPKADYGKFYNGDSYIVLQTTCSKGGGAYLFDIHFWIGKDS 74
[Close]
BLAST of Gelsolin vs. TrEMBL
Match: V3ZUV4 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_214936 PE=4 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 1.250e-39
Identity = 74/102 (72.55%), Postives = 81/102 (79.41%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            +G+IKQK YDWKDSNLALFGSD EK VKK SAETEPAW+   A  + G+ VWRI KFKV   PKEE+GKFYNGDSYIIL   KE DS EL YDVHFWIGK+S
Sbjct:    2 SGLIKQKEYDWKDSNLALFGSDVEKNVKKESAETEPAWK--NAGQMVGVQVWRIVKFKVTQWPKEEYGKFYNGDSYIILNTYKEADSNELQYDVHFWIGKHS 101
[Close]
BLAST of Gelsolin vs. TrEMBL
Match: A0A210Q180 (Gelsolin-like protein 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT11070 PE=4 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 2.629e-39
Identity = 71/102 (69.61%), Postives = 81/102 (79.41%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            TG+IKQK YDWKDSNLALFGSDT++ VKK SAETEPAW+  KA    G+ +WRI KFKV   PKE++GKFY+GDSYIIL   +EE   E LYDVHFWIGKYS
Sbjct:    2 TGLIKQKQYDWKDSNLALFGSDTDRQVKKESAETEPAWK--KAGEKVGIQIWRIVKFKVTHWPKEDYGKFYDGDSYIILNTFQEEGGEEFLYDVHFWIGKYS 101
[Close]
BLAST of Gelsolin vs. TrEMBL
Match: A0A2T7NTD6 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_14907 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 9.396e-38
Identity = 72/101 (71.29%), Postives = 77/101 (76.24%), Query Frame = 3 
Query:  228 GMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            G+IK K YDWKDSNLALFGSD E  VKK SAE EPAWR  KA    GL +WRI KFKV   PK E+GKFYNGDSYIIL   +EE S +LLYDVHFWIGKYS
Sbjct:    3 GLIKPKQYDWKDSNLALFGSDVENQVKKESAECEPAWR--KAGQEFGLQIWRIVKFKVTEWPKSEYGKFYNGDSYIILNTYQEEGSDQLLYDVHFWIGKYS 101
[Close]
BLAST of Gelsolin vs. TrEMBL
Match: A0A3S0ZL59 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_011945 PE=4 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 1.122e-37
Identity = 66/102 (64.71%), Postives = 82/102 (80.39%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            +G++K K YDWKDSN+ALFGSDTEK VKK SAE+EPAW+   A   PGL +WRI KFKV   P++E+GKF++GDSYIIL   KEE + +LL+DVHFWIG+YS
Sbjct:    2 SGLVKAKKYDWKDSNMALFGSDTEKQVKKESAESEPAWK--NAGQAPGLQIWRIVKFKVTHQPQDEYGKFFSGDSYIILNTYKEEGNEQLLHDVHFWIGQYS 101
[Close]
BLAST of Gelsolin vs. TrEMBL
Match: Q703I5 (Gelsolin OS=Suberites ficus OX=86007 GN=gelS PE=2 SV=1)

HSP 1 Score: 140.584 bits (353), Expect = 4.760e-37
Identity = 71/102 (69.61%), Postives = 78/102 (76.47%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            +G +K K YDWKDSNLALFGSDTEK VKK SAETEPAW+ A      GL +WRI KFKV   P +E+G FYNGDSYIIL   KE+DS  LLYDVHFWIGKYS
Sbjct:    2 SGFVKPKKYDWKDSNLALFGSDTEKQVKKDSAETEPAWKGAGQEV--GLQIWRIVKFKVKHWPADEYGSFYNGDSYIILNTYKEKDSDALLYDVHFWIGKYS 101
[Close]
BLAST of Gelsolin vs. Ensembl Cavefish
Match: gsna (gelsolin-like [Source:NCBI gene;Acc:103033745])

HSP 1 Score: 68.1662 bits (165), Expect = 2.009e-13
Identity = 29/61 (47.54%), Postives = 42/61 (68.85%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            +A   PGL VWRIEKF ++++P+  +G FY GD+Y+IL   K+  S  L YD+HFW+G + 
Sbjct:    9 RAGKQPGLQVWRIEKFDLVAVPENLYGGFYTGDAYVILNTIKQR-SGNLQYDLHFWLGDHC 68
[Close]
BLAST of Gelsolin vs. Ensembl Cavefish
Match: gsna (gelsolin-like [Source:NCBI gene;Acc:103033745])

HSP 1 Score: 65.855 bits (159), Expect = 1.254e-12
Identity = 29/60 (48.33%), Postives = 42/60 (70.00%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKY 527
            +A   PGL VWRIEKF ++++P+  +G FY GD+Y+IL   K+  S  L YD+HFW+G +
Sbjct:    9 RAGKQPGLQVWRIEKFDLVAVPENLYGGFYTGDAYVILNTIKQR-SGNLQYDLHFWLGDH 67
[Close]
BLAST of Gelsolin vs. Ensembl Cavefish
Match: gsnb (gelsolin [Source:NCBI gene;Acc:103027267])

HSP 1 Score: 63.1586 bits (152), Expect = 9.408e-12
Identity = 29/59 (49.15%), Postives = 39/59 (66.10%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGK 524
            KA   PGL VWRIEK  ++S+P+  +G FY GD+YI+L   K+     L YD+HFW G+
Sbjct:    9 KAGQQPGLQVWRIEKMDLVSVPENLYGSFYTGDTYIVLNTIKQHLG-NLQYDLHFWQGE 66
[Close]
BLAST of Gelsolin vs. Ensembl Cavefish
Match: avil (advillin [Source:NCBI gene;Acc:103036458])

HSP 1 Score: 62.3882 bits (150), Expect = 1.674e-11
Identity = 28/68 (41.18%), Postives = 42/68 (61.76%), Query Frame = 3 
Query:  327 EPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            E  +R    T  PG+ +WRIEK +++ +P++ +G FY GD Y++L   K   S  L YD+H+WIG  S
Sbjct:    2 EQTFRAVNQT--PGILIWRIEKMELVLVPEKSYGNFYEGDCYVLLCTKKVGGS--LSYDIHYWIGSES 65
[Close]
BLAST of Gelsolin vs. Ensembl Cavefish
Match: avil (advillin [Source:NCBI gene;Acc:103036458])

HSP 1 Score: 62.3882 bits (150), Expect = 2.019e-11
Identity = 28/68 (41.18%), Postives = 42/68 (61.76%), Query Frame = 3 
Query:  327 EPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            E  +R    T  PG+ +WRIEK +++ +P++ +G FY GD Y++L   K   S  L YD+H+WIG  S
Sbjct:    2 EQTFRAVNQT--PGILIWRIEKMELVLVPEKSYGNFYEGDCYVLLCTKKVGGS--LSYDIHYWIGSES 65
[Close]
BLAST of Gelsolin vs. Ensembl Sea Lamprey
Match: avil (advillin [Source:ZFIN;Acc:ZDB-GENE-060421-6683])

HSP 1 Score: 64.6994 bits (156), Expect = 5.556e-13
Identity = 25/55 (45.45%), Postives = 38/55 (69.09%), Query Frame = 3 
Query:  366 GLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            GL +WR+EK ++ ++P++ +G F+ GD YIIL   K   SP   YDVH+W+G+ S
Sbjct:   13 GLHIWRVEKMELAAVPQKAYGSFFEGDCYIILSAKKAGSSPTPTYDVHYWVGQES 67
[Close]
BLAST of Gelsolin vs. Ensembl Sea Lamprey
Match: gsna (gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653])

HSP 1 Score: 62.3882 bits (150), Expect = 1.566e-12
Identity = 25/57 (43.86%), Postives = 39/57 (68.42%), Query Frame = 3 
Query:  351 ATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            A   PGL VWR+EK  ++++PKE +G FY GD+Y++L  +    +  + YD+HFW+G
Sbjct:   10 AGRQPGLQVWRVEKLDLVAVPKELYGSFYTGDAYVLL-FSVRNRAGNMQYDLHFWLG 65
[Close]
BLAST of Gelsolin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008894.1 (pep scaffold:Pmarinus_7.0:GL484493:7018:36468:1 gene:ENSPMAG00000008055.1 transcript:ENSPMAT00000008894.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.2098 bits (108), Expect = 1.113e-6
Identity = 22/55 (40.00%), Postives = 37/55 (67.27%), Query Frame = 3 
Query:  360 VPGLFVWRIEKFKVISLPKEEF-GKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            +PG+ VW IE F V  L +E + GKFY+ D YI+L+   +E+   + +++++WIG
Sbjct:  497 IPGVSVWHIENF-VPQLTEEYYHGKFYDADCYIVLRTFIDENGA-IAWEIYYWIG 549
[Close]
BLAST of Gelsolin vs. Ensembl Nematostella
Match: EDO43191 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ88])

HSP 1 Score: 130.954 bits (328), Expect = 2.426e-37
Identity = 66/102 (64.71%), Postives = 76/102 (74.51%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            +G++K K YDWKDSNLALFGSD EK VKK SAE EPAW  A      G+ VWRI KFKV   PKE++GKF+NGDSYI+L   KE  +  LLYDVHFWIGK+S
Sbjct:    2 SGLVKAKKYDWKDSNLALFGSDLEKNVKKESAEGEPAWEGAGKEV--GVQVWRIVKFKVEHWPKEDYGKFFNGDSYIVLNTYKEPSTENLLYDVHFWIGKFS 101
[Close]
BLAST of Gelsolin vs. Ensembl Nematostella
Match: EDO40348 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7K4])

HSP 1 Score: 127.872 bits (320), Expect = 5.459e-36
Identity = 66/102 (64.71%), Postives = 77/102 (75.49%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            +G+ KQK YDWKDSNLALFGSDTEK VKK SA+TE AW    A   PG+ +WRI KFKV   P+E +G FYNGDSYIIL+  KE +  EL++DVHFWIGK S
Sbjct:    2 SGLRKQKEYDWKDSNLALFGSDTEKNVKKESAQTETAW--IGAGEKPGMKIWRIVKFKVTKWPEENYGSFYNGDSYIILRTKKENE--ELVHDVHFWIGKKS 99
[Close]
BLAST of Gelsolin vs. Ensembl Nematostella
Match: EDO43190 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ87])

HSP 1 Score: 124.02 bits (310), Expect = 1.721e-34
Identity = 64/106 (60.38%), Postives = 76/106 (71.70%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSP----ELLYDVHFWIGKYS 530
            +G++K K YDWKDSNLALFGSD EK VKK SAE EPAW  A      G+ VWRI KFKV   PK+++G FYNGDSYI+L   K++ S     EL YDVHFWIG++S
Sbjct:    2 SGLVKAKKYDWKDSNLALFGSDLEKNVKKESAEGEPAWEGAGKEV--GVQVWRIVKFKVTHWPKQDYGHFYNGDSYIVLNTYKKDPSSEACGELSYDVHFWIGRFS 105
[Close]
BLAST of Gelsolin vs. Ensembl Nematostella
Match: EDO49235 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGV0])

HSP 1 Score: 116.701 bits (291), Expect = 9.077e-32
Identity = 61/102 (59.80%), Postives = 73/102 (71.57%), Query Frame = 3 
Query:  225 TGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            +G+ KQK  +WKD+NLALFGSD EK VK+ +A TE AW+   A T  GL +WRIEKFKV    +E++G FY+GDSYIIL   KE    EL YDVHFWIGK S
Sbjct:    2 SGLRKQKQPEWKDTNLALFGSDIEKNVKREAAATEIAWK--NAGTREGLQIWRIEKFKVKVWSREDYGSFYDGDSYIILNTYKESGEDELKYDVHFWIGKDS 101
[Close]
BLAST of Gelsolin vs. Ensembl Nematostella
Match: EDO49236 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGV1])

HSP 1 Score: 111.309 bits (277), Expect = 2.244e-31
Identity = 58/103 (56.31%), Postives = 74/103 (71.84%), Query Frame = 3 
Query:  222 KTGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            K G+ KQK  + KDSNLALFG+D E+ VKK++AE E AW+ A      GL +WRI KFKV   PKE++G+FY GDSYIIL   +E++  EL YD+HFWIG+ S
Sbjct:    3 KKGLTKQKKTELKDSNLALFGTDIERNVKKSAAEGEVAWKNAGEKV--GLQIWRINKFKVEEWPKEKYGQFYAGDSYIILWTYEEKEDTELCYDLHFWIGRGS 103
[Close]
BLAST of Gelsolin vs. Ensembl Medaka
Match: gsna (gelsolin [Source:NCBI gene;Acc:101167720])

HSP 1 Score: 65.0846 bits (157), Expect = 2.323e-12
Identity = 27/58 (46.55%), Postives = 41/58 (70.69%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            +A   PGL VWR+EKF ++ +P+  +G FY GD+Y++L   K+  S +L YD+HFW+G
Sbjct:  106 RAGKNPGLQVWRVEKFNLVPVPENLYGGFYTGDAYLVLNTIKQR-SGQLQYDLHFWLG 162
[Close]
BLAST of Gelsolin vs. Ensembl Medaka
Match: gsna (gelsolin [Source:NCBI gene;Acc:101167720])

HSP 1 Score: 65.0846 bits (157), Expect = 2.408e-12
Identity = 27/58 (46.55%), Postives = 41/58 (70.69%), Query Frame = 3 
Query:  348 KATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIG 521
            +A   PGL VWR+EKF ++ +P+  +G FY GD+Y++L   K+  S +L YD+HFW+G
Sbjct:  106 RAGKNPGLQVWRVEKFNLVPVPENLYGGFYTGDAYLVLNTIKQR-SGQLQYDLHFWLG 162
[Close]
BLAST of Gelsolin vs. Ensembl Medaka
Match: capgb (capping actin protein, gelsolin like [Source:NCBI gene;Acc:101163360])

HSP 1 Score: 61.2326 bits (147), Expect = 2.943e-11
Identity = 28/56 (50.00%), Postives = 38/56 (67.86%), Query Frame = 3 
Query:  363 PGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            PGL+VWR+EK K + L   E G FYNGDSY++LK + E+ +     D+H WIG+ S
Sbjct:   18 PGLWVWRVEKMKAVLLDPSEVGSFYNGDSYLVLKNDGEQGA-----DLHMWIGEKS 68
[Close]
BLAST of Gelsolin vs. Ensembl Medaka
Match: avil (advillin [Source:NCBI gene;Acc:101170835])

HSP 1 Score: 56.225 bits (134), Expect = 2.381e-9
Identity = 23/59 (38.98%), Postives = 39/59 (66.10%), Query Frame = 3 
Query:  354 TTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            T  PG+ +WR+EK +++ + ++  G FY GD Y++L  +K ++   L YD+H+WIG  S
Sbjct:    9 THNPGIIIWRVEKMELVLVSEKTHGNFYEGDCYVLLSTHKVKNV--LSYDIHYWIGSES 65
[Close]
BLAST of Gelsolin vs. Ensembl Medaka
Match: vill (villin like [Source:NCBI gene;Acc:101155645])

HSP 1 Score: 55.8398 bits (133), Expect = 3.357e-9
Identity = 23/55 (41.82%), Postives = 36/55 (65.45%), Query Frame = 3 
Query:  366 GLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            GL +W I   K++S+P + FG F+ GD YI+L I + + + + + DVH+WIG  S
Sbjct:   36 GLQIWTINNMKMVSVPTKAFGNFFEGDCYIVLNIRENKGAAQSI-DVHYWIGNSS 89
[Close]
BLAST of Gelsolin vs. Planmine SMEST
Match: SMESG000035418.1 (SMESG000035418.1)

HSP 1 Score: 252.292 bits (643), Expect = 1.206e-83
Identity = 126/143 (88.11%), Postives = 126/143 (88.11%), Query Frame = 3 
Query:  102 MKLDFKSKSXXXXXXXXXXXKGNNYGAVEEVLVTGHRKSDKTGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            MKLDFK                NNYGAVEEVLVTGHRKSDKTGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGK S
Sbjct:    1 MKLDFKR---------------NNYGAVEEVLVTGHRKSDKTGMIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKQS 128
[Close]
BLAST of Gelsolin vs. Planmine SMEST
Match: SMESG000015535.1 (SMESG000015535.1)

HSP 1 Score: 169.859 bits (429), Expect = 7.567e-52
Identity = 77/100 (77.00%), Postives = 89/100 (89.00%), Query Frame = 3 
Query:  231 MIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            MIKQK YDWKDSNL+LFGSDTEKLVKKTS+ETE AW++ K  T P LF+WRIEKFKV++ PKE++GKF+NGDSYIILKI KEE+SPEL YD+HFWIGK S
Sbjct:    1 MIKQKKYDWKDSNLSLFGSDTEKLVKKTSSETEAAWKLVKTVTTPSLFIWRIEKFKVVNWPKEDYGKFFNGDSYIILKIKKEENSPELFYDIHFWIGKRS 100
[Close]
BLAST of Gelsolin vs. Planmine SMEST
Match: SMESG000015928.1 (SMESG000015928.1)

HSP 1 Score: 130.568 bits (327), Expect = 1.029e-36
Identity = 62/100 (62.00%), Postives = 77/100 (77.00%), Query Frame = 3 
Query:  231 MIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            M K K YDWKDSN+ L GS  ++ VKK+SAE EPAW+ AKA +   LF+WRIEKFKV+  P+++ G+FY GDSYI+L I + E+  ELLYDVHFWIGKYS
Sbjct:    1 MQKTKKYDWKDSNVELIGSSEDRAVKKSSAENEPAWKKAKACSHSELFIWRIEKFKVVEWPQKQHGEFYEGDSYIVLNIYQREN--ELLYDVHFWIGKYS 98
[Close]
BLAST of Gelsolin vs. Planmine SMEST
Match: SMESG000015924.1 (SMESG000015924.1)

HSP 1 Score: 126.331 bits (316), Expect = 4.467e-35
Identity = 59/100 (59.00%), Postives = 74/100 (74.00%), Query Frame = 3 
Query:  231 MIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            M K + YDWKDSN+ L GS  ++ VKK+SA+TE AW  AK      LF+WRIEKFKV+  PK+ FG+F+ GDSYI+L I ++E   ELLYD+HFWIGKYS
Sbjct:    1 MKKAEKYDWKDSNVELIGSSEDRSVKKSSADTEKAWNAAKTCKTTALFIWRIEKFKVVEWPKQRFGEFFEGDSYIVLNIYQKE--KELLYDIHFWIGKYS 98
[Close]
BLAST of Gelsolin vs. Planmine SMEST
Match: SMESG000015925.1 (SMESG000015925.1)

HSP 1 Score: 125.561 bits (314), Expect = 1.007e-34
Identity = 60/100 (60.00%), Postives = 72/100 (72.00%), Query Frame = 3 
Query:  231 MIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVWRIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS 530
            M+K K Y WKDSN+ L G+  ++ +KK SAETE AW   K+   P LF+WRIEKFKV+  PK +FG+FYNGDSYIIL I       E+LYDVHFWIGKYS
Sbjct:    1 MVKPKKYSWKDSNVELIGTKEDRSIKKISAETEKAWAKVKSCNHPELFIWRIEKFKVVEWPKNQFGEFYNGDSYIILNIYTR--GNEILYDVHFWIGKYS 98
The following BLAST results are available for this feature:
BLAST of Gelsolin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
VIL18.852e-1542.11villin 1 [Source:HGNC Symbol;Acc:HGNC:12690][more]
VIL18.333e-1450.00villin 1 [Source:HGNC Symbol;Acc:HGNC:12690][more]
VIL11.669e-1350.00villin 1 [Source:HGNC Symbol;Acc:HGNC:12690][more]
GSN5.286e-1143.10gelsolin [Source:HGNC Symbol;Acc:HGNC:4620][more]
GSN6.102e-1143.10gelsolin [Source:HGNC Symbol;Acc:HGNC:4620][more]
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BLAST of Gelsolin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
gsnl-11.347e-645.28Gelsolin-like protein 1 [Source:UniProtKB/Swiss-P... [more]
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BLAST of Gelsolin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gel1.303e-1247.46gene:FBgn0010225 transcript:FBtr0078973[more]
Gel1.303e-1247.46gene:FBgn0010225 transcript:FBtr0309256[more]
Gel1.303e-1247.46gene:FBgn0010225 transcript:FBtr0078969[more]
Gel1.303e-1247.46gene:FBgn0010225 transcript:FBtr0078968[more]
Gel1.389e-1247.46gene:FBgn0010225 transcript:FBtr0309257[more]
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BLAST of Gelsolin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gsna4.726e-1450.00gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653][more]
gsna4.726e-1450.00gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653][more]
gsna6.838e-1450.00gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653][more]
gsna7.367e-1450.00gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653][more]
gsna7.367e-1450.00gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653][more]
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BLAST of Gelsolin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000019805.11.932e-1444.26gelsolin-like [Source:NCBI gene;Acc:108644441][more]
vil11.401e-1037.93villin 1 [Source:NCBI gene;Acc:100124960][more]
jazf11.180e-945.61JAZF zinc finger 1 [Source:Xenbase;Acc:XB-GENE-950... [more]
jazf11.320e-945.61JAZF zinc finger 1 [Source:Xenbase;Acc:XB-GENE-950... [more]
jazf16.700e-942.11JAZF zinc finger 1 [Source:Xenbase;Acc:XB-GENE-950... [more]
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BLAST of Gelsolin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Vil18.242e-1344.83villin 1 [Source:MGI Symbol;Acc:MGI:98930][more]
Gsn2.526e-1143.10gelsolin [Source:MGI Symbol;Acc:MGI:95851][more]
Gsn4.277e-1143.10gelsolin [Source:MGI Symbol;Acc:MGI:95851][more]
Gsn4.277e-1143.10gelsolin [Source:MGI Symbol;Acc:MGI:95851][more]
Gsn9.002e-1134.88gelsolin [Source:MGI Symbol;Acc:MGI:95851][more]
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BLAST of Gelsolin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7JQD3|GELS1_LUMTE9.398e-3465.05Gelsolin-like protein 1 OS=Lumbricus terrestris OX... [more]
sp|Q24800|SEVE_ECHGR1.843e-3050.98Severin OS=Echinococcus granulosus OX=6210 GN=AG8 ... [more]
sp|Q8MPM1|GELS2_LUMTE1.532e-2652.94Gelsolin-like protein 2 OS=Lumbricus terrestris OX... [more]
sp|P10733|SEVE_DICDI4.010e-2044.55Severin OS=Dictyostelium discoideum OX=44689 GN=se... [more]
sp|Q10L71|VLN2_ORYSJ1.891e-1453.57Villin-2 OS=Oryza sativa subsp. japonica OX=39947 ... [more]
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BLAST of Gelsolin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V3ZUV41.250e-3972.55Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
A0A210Q1802.629e-3969.61Gelsolin-like protein 1 OS=Mizuhopecten yessoensis... [more]
A0A2T7NTD69.396e-3871.29Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A3S0ZL591.122e-3764.71Uncharacterized protein OS=Elysia chlorotica OX=18... [more]
Q703I54.760e-3769.61Gelsolin OS=Suberites ficus OX=86007 GN=gelS PE=2 ... [more]
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BLAST of Gelsolin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gsna2.009e-1347.54gelsolin-like [Source:NCBI gene;Acc:103033745][more]
gsna1.254e-1248.33gelsolin-like [Source:NCBI gene;Acc:103033745][more]
gsnb9.408e-1249.15gelsolin [Source:NCBI gene;Acc:103027267][more]
avil1.674e-1141.18advillin [Source:NCBI gene;Acc:103036458][more]
avil2.019e-1141.18advillin [Source:NCBI gene;Acc:103036458][more]
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BLAST of Gelsolin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
avil5.556e-1345.45advillin [Source:ZFIN;Acc:ZDB-GENE-060421-6683][more]
gsna1.566e-1243.86gelsolin a [Source:ZFIN;Acc:ZDB-GENE-030131-9653][more]
ENSPMAT00000008894.11.113e-640.00pep scaffold:Pmarinus_7.0:GL484493:7018:36468:1 ge... [more]
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BLAST of Gelsolin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Gelsolin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO431912.426e-3764.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO403485.459e-3664.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO431901.721e-3460.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO492359.077e-3259.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO492362.244e-3156.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Gelsolin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gsna2.323e-1246.55gelsolin [Source:NCBI gene;Acc:101167720][more]
gsna2.408e-1246.55gelsolin [Source:NCBI gene;Acc:101167720][more]
capgb2.943e-1150.00capping actin protein, gelsolin like [Source:NCBI ... [more]
avil2.381e-938.98advillin [Source:NCBI gene;Acc:101170835][more]
vill3.357e-941.82villin like [Source:NCBI gene;Acc:101155645][more]
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BLAST of Gelsolin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000035418.11.206e-8388.11SMESG000035418.1[more]
SMESG000015535.17.567e-5277.00SMESG000015535.1[more]
SMESG000015928.11.029e-3662.00SMESG000015928.1[more]
SMESG000015924.14.467e-3559.00SMESG000015924.1[more]
SMESG000015925.11.007e-3460.00SMESG000015925.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014940 ID=SMED30014940|Name=Gelsolin|organism=Schmidtea mediterranea sexual|type=transcript|length=530bp
CAAATAAATTTTCGTTTCGTAATTATTTAAATTTCACATGTTTTTTATTT
AACTATAAATTCTGGAAAATAAATTAATTTTACATTCAATTAATTCAAAC
AATGAAATTAGATTTTAAAAGTAAATCATTTCTAGAATTTTTTGTTTTTT
AAACTTTCTAAAAAGGAAACAACTACGGAGCAGTCGAAGAAGTTCTTGTC
ACCGGACACAGAAAGTCTGACAAAACCGGAATGATAAAACAAAAAAACTA
CGATTGGAAAGATTCCAATTTGGCTTTGTTTGGATCAGACACGGAAAAAT
TAGTAAAAAAAACTTCCGCTGAAACCGAACCAGCATGGAGAGTTGCTAAG
GCAACTACGGTTCCAGGTTTATTTGTTTGGAGAATAGAAAAATTCAAAGT
CATCAGTTTACCAAAGGAAGAATTCGGAAAATTTTACAATGGAGATTCTT
ACATTATTTTGAAAATCAATAAAGAAGAAGACAGTCCGGAGTTGCTATAC
GATGTGCATTTTTGGATTGGAAAATATTCT
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protein sequence of SMED30014940-orf-1

>SMED30014940-orf-1 ID=SMED30014940-orf-1|Name=SMED30014940-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=100bp
MIKQKNYDWKDSNLALFGSDTEKLVKKTSAETEPAWRVAKATTVPGLFVW
RIEKFKVISLPKEEFGKFYNGDSYIILKINKEEDSPELLYDVHFWIGKYS
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Aliases
The feature 'Gelsolin' has the following synonyms
Synonym
gelsolin-like
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0051015actin filament binding
GO:0003779actin binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000029primitive ectoderm
PLANA:0000058embryonic digestive system
PLANA:0000211primitive ectoderm cell
PLANA:0000023embryonic pharynx
Vocabulary: INTERPRO
TermDefinition
IPR007122Villin/Gelsolin
IPR030009Villin-2_plant
IPR029006ADF-H/Gelsolin-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0051017actin filament bundle assembly
Vocabulary: Schmidtea mediterranea Developmental Stages
TermDefinition
PLANA:0000005Stage 5
PLANA:0000003Stage 3
PLANA:0000002Stage 2
PLANA:0000004Stage 4
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR029006ADF-H/Gelsolin-like domain superfamilyGENE3DG3DSA:3.40.20.10coord: 29..98
e-value: 1.4E-18
score: 68.8
IPR007122Villin/GelsolinPANTHERPTHR11977VILLINcoord: 33..98
IPR030009Villin-2, plantPANTHERPTHR11977:SF98coord: 33..98
NoneNo IPR availableSUPERFAMILYSSF55753Actin depolymerizing proteinscoord: 43..98