Formin-like protein
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014928 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 15
Homology
BLAST of Formin-like protein vs. Ensembl Human
Match: FMNL2 (formin like 2 [Source:HGNC Symbol;Acc:HGNC:18267]) HSP 1 Score: 227.639 bits (579), Expect = 3.217e-60 Identity = 171/511 (33.46%), Postives = 277/511 (54.21%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXG----INRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S ++ +++S +T+ + D S ++S+ + S N + SG + NT + K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V++MQFINI+VHSVE++N RV+LQYEFT LGLD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + R+S ++++I +L Q G I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-------------------FAQYAVTFDFESVESTVESS---VDKSKPWSRSIEDLHRGS--NLPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLV--SKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQ-RQSTLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 166.007 bits (419), Expect = 8.232e-41 Identity = 149/499 (29.86%), Postives = 243/499 (48.70%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXX----XXXXXXXXPKGDQTRKKN---------RTRQI--------NADGIMDEIMAGLDYQPLQAGLHARRGKRDNTD 3364
P+ W L+ Q GTVF EID +I + L++D FE+IFK + P +D K ++ G+N K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ LP+ E + R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ ++EK+ + F++EL YVE A+ VSL N++ +EL G+D E ++ + T L F+ N ++ L++ + A+ AF V++FGE + +T P +FF VRF+ ++K+A EN R+ ++ +K + +PK + K R RQ+ DG +++I+ L QP + RR R D
Sbjct: 627 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKT-----KAQGPAIDLSSSK------------QKIPQKGSN----KVTLLEANRAKNL----------------AITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHN---------TLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFD 1078
BLAST of Formin-like protein vs. Ensembl Human
Match: FMNL3 (formin like 3 [Source:HGNC Symbol;Acc:HGNC:23698]) HSP 1 Score: 217.624 bits (553), Expect = 3.816e-57 Identity = 157/466 (33.69%), Postives = 251/466 (53.86%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRD 1465
P P+ E E+R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++ +T K + Q + ++L EISLRTNH+ WV +FL ++ GL++LVDY+S + M F +G + +S +I + S S SL R S R S + + + S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E RF+ LM ++R+ +D NID+ V+ MQFINI+VHSVE++N RV+LQYEFT LGL+ FL+K + ++L Q+ AYLDN+ D LLEDAE K + + E LE+ +S L E+L E E ++ E E ++ + EKELE + + S V +LR I++
Sbjct: 27 PMPEPCE-LEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLS-----FAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSLAR----SARQSVLRYSTLPGRRALKNSRLV-------------SQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN------EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKE 460 HSP 2 Score: 206.068 bits (523), Expect = 1.696e-53 Identity = 153/489 (31.29%), Postives = 242/489 (49.49%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXXXXXXXXXXPKGDQTRKKN-----------RTRQI--------NADGIMDEIMAGLDYQPLQAGLHAR 3340
P+ W L+ Q GTVF E+D +I + LDLD FE++FK + P LD I K A + K++LL+ NR K + +I+ R+ GR + AI FD+ + D L+ LP+ E + R E L LA EDR + L S ++R+ ++ + ++ F + L ++ + A SV SQKLK++LEI+LA GN MN S+RG GF++QSLD+L + +S D K +L+++IA ++EK+PDL NF+ EL +VE A+ VSL N++ +EL G++ + E S+ N+V L NF+ N +++ L+ + A+ A+ V +FGE +T P +FF VRF+ S+K+A EN R+ +E R+K ++ + ++N R RQ DG +++I+ GL QP+ AR
Sbjct: 572 PVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKT-----KAQGPALDLICSKN----------------KTAQKAASKVTLLEANRAKNL----------------AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSV----------LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESP-KTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQAR 1012
BLAST of Formin-like protein vs. Ensembl Human
Match: FMNL3 (formin like 3 [Source:HGNC Symbol;Acc:HGNC:23698]) HSP 1 Score: 217.238 bits (552), Expect = 5.537e-57 Identity = 161/492 (32.72%), Postives = 258/492 (52.44%), Query Frame = 2
Query: 17 MGNQQQGSPYP----RLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRD 1465
MGN + P + + P P+ E E+R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++ +T K + Q + ++L EISLRTNH+ WV +FL ++ GL++LVDY+S + M F +G + +S +I + S S SL R S R S + + + S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E RF+ LM ++R+ +D NID+ V+ MQFINI+VHSVE++N RV+LQYEFT LGL+ FL+K + ++L Q+ AYLDN+ D LLEDAE K + + E LE+ +S L E+L E E ++ E E ++ + EKELE + + S V +LR I++
Sbjct: 1 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCE-LEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLS-----FAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSLAR----SARQSVLRYSTLPGRRALKNSRLV-------------SQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN------EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKE 460 HSP 2 Score: 199.519 bits (506), Expect = 2.386e-51 Identity = 137/413 (33.17%), Postives = 214/413 (51.82%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF E+D +I + LDLD FE++FK + P LD I K A + K++LL+ NR K + +I+ R+ GR + AI FD+ + D L+ LP+ E + R E L LA EDR + L S ++R+ ++ + ++ F + L ++ + A SV SQKLK++LEI+LA GN MN S+RG GF++QSLD+L + +S D K +L+++IA ++EK+PDL NF+ EL +VE A+ VSL N++ +EL G++ + E S+ N+V L NF+ N +++ L+ + A+ A+ V +FGE +T P +FF VRF+ S+K+A EN R+
Sbjct: 572 PVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKT-----KAQGPALDLICSKN----------------KTAQKAASKVTLLEANRAKNL----------------AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSV----------LRNFLSTNEGKLDKLQRDAKTAE-AYNAVVRYFGESP-KTTPPSVFFPVFVRFIRSYKEAEQENEARK 935
BLAST of Formin-like protein vs. Ensembl Human
Match: FMNL3 (formin like 3 [Source:HGNC Symbol;Acc:HGNC:23698]) HSP 1 Score: 206.838 bits (525), Expect = 8.408e-54 Identity = 153/489 (31.29%), Postives = 242/489 (49.49%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXXXXXXXXXXPKGDQTRKKN-----------RTRQI--------NADGIMDEIMAGLDYQPLQAGLHAR 3340
P+ W L+ Q GTVF E+D +I + LDLD FE++FK + P LD I K A + K++LL+ NR K + +I+ R+ GR + AI FD+ + D L+ LP+ E + R E L LA EDR + L S ++R+ ++ + ++ F + L ++ + A SV SQKLK++LEI+LA GN MN S+RG GF++QSLD+L + +S D K +L+++IA ++EK+PDL NF+ EL +VE A+ VSL N++ +EL G++ + E S+ N+V L NF+ N +++ L+ + A+ A+ V +FGE +T P +FF VRF+ S+K+A EN R+ +E R+K ++ + ++N R RQ DG +++I+ GL QP+ AR
Sbjct: 521 PVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKT-----KAQGPALDLICSKN----------------KTAQKAASKVTLLEANRAKNL----------------AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSV----------LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESP-KTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQAR 961 HSP 2 Score: 179.104 bits (453), Expect = 4.764e-45 Identity = 106/248 (42.74%), Postives = 159/248 (64.11%), Query Frame = 2
Query: 722 SIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRD 1465
S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E RF+ LM ++R+ +D NID+ V+ MQFINI+VHSVE++N RV+LQYEFT LGL+ FL+K + ++L Q+ AYLDN+ D LLEDAE K + + E LE+ +S L E+L E E ++ E E ++ + EKELE + + S V +LR I++
Sbjct: 168 SQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN------EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKE 409 HSP 3 Score: 63.929 bits (154), Expect = 2.016e-9 Identity = 38/122 (31.15%), Postives = 70/122 (57.38%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMS 433
P P+ E E+R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++ +T K + Q + ++L EISLRTNH+ WV +FL ++ GL++LVDY+S
Sbjct: 27 PMPEPCE-LEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLS 144
BLAST of Formin-like protein vs. Ensembl Human
Match: FMNL1 (formin like 1 [Source:HGNC Symbol;Acc:HGNC:1212]) HSP 1 Score: 205.297 bits (521), Expect = 5.028e-53 Identity = 158/467 (33.83%), Postives = 246/467 (52.68%), Query Frame = 2
Query: 104 DFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYK-------------MTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLR 1450
+ E+R+ + +++ P +Q + Q + +K EL+ + F+ KNP + I+ L+SY M+N K Q + Q+L E SLRTNH+ WV +FL ++ GL++ LL + + + M T+ +SN + E +E D S S+ + R+ T + RN+ V S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGH+ +L AFD FK + E+ RF+ LM ++R+ +D NID+ V+ MQFINI+VHSVEN+N RV+LQYEFT LGLD +L++L+ D+L Q+ AYLDN+ D LLED E K A + E L++ ++LL E+L E E KI E E ++ +A KELE + R E + + S R
Sbjct: 34 ELEERFNRALNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAA------YIQKLKSYVDTGGVSRKVAADWMSNLGFKRRVQESTQVLRELETSLRTNHIGWVQEFLNEENRGLDV--------LLEYLAFAQCSV-TYDMESTDNGASNSEKNKPL--EQSVE-DLSKGPPSSVPK-----SRHLTIKLTPAHSRKAL-RNSRIV------------SQKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFRN------EDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGPSRR 458 HSP 2 Score: 164.466 bits (415), Expect = 2.646e-40 Identity = 127/407 (31.20%), Postives = 198/407 (48.65%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQK--CIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAAD---RLLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISE 3154
PL+ W L+ Q GTVF E++ ++ ++LD+ FE+ FK + P LD + L A K +L++ NR K I + L E++ Q AI +D+ + D L+ LP+ E + E + L+ EDR + S I R+ ++ + ++ F +T L ++ + A S+ S KL++ILEIVLAFGN MN S+RG A GFR+QSLD L E +S D K +L++Y+ I EK+P L F S+L +++ A VSL +++A L GL+ E V + ++ L F+R N ++ L ++ A+ AF VE+FGE + +T SP LFF RF+ ++KKA E
Sbjct: 643 PLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKT-----KSQGPSLDL----------------SALKSKAAQKAPSKATLIEANRAKNLAITLRKGNLGAERICQ---------------AIEAYDLQALGLDFLELLMRFLPTEYERSLITRFEREQRPMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLADVRSLQRGLELTQREF------VRQDDCMV---LKEFLRANSPTMDKLLADSKTAQEAFESVVEYFGE-NPKTTSPGLFFSLFSRFIKAYKKAEQE 1003
BLAST of Formin-like protein vs. Ensembl Celegans
Match: frl-1 (FRL (Formin Related gene in Leukocytes) homolog [Source:UniProtKB/TrEMBL;Acc:Q9BL72]) HSP 1 Score: 154.066 bits (388), Expect = 1.436e-37 Identity = 108/338 (31.95%), Postives = 179/338 (52.96%), Query Frame = 2
Query: 317 QNAKQILSATEISLRTNHVEWVYDFLK--HSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIES-DFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQL 1321
+ + +L EISLRTN V+WV++FL + GL LVDYM +L S P T +G N + + + N S + SP N S ++ S + S S ++ + + K G+++ + +H+C+ C R I+NN++G Q F D I I ++H + +TK+L+L +LS++C ++GG E V AFD F+ RE +RF TLM F H ++++++ S +QF V+ V+++N RV+LQYE TLLGLD ++ + E D L ++ +Y +N +D LL+D+ K + E ER+ +S +E++
Sbjct: 91 ETSTSVLRHIEISLRTNSVDWVFEFLNTPNLGLRKLVDYMRTLLADCAPS-----VPSTSSGLPAGFLNSTANSSVGANNNHSSLNESPSHNSS----YEMSTTTTANTSNSFDATANLLKKGPLTISKGKVAKTTGEAVDD-IHICMMCLRAIMNNKQGFQQVFADTDAIYCIVRSILHQNLRTKTLVLQMLSSICWVQGGQELVSDAFDRFEKDFREPRRFWTLMQFVSHP-----PEFHVEFLSSAVQFFYYFVN-VDDLNFRVHLQYEMTLLGLDKYIDMMAECESDELQERMISYQNNGIDVQQLLDDSNQKTELLDENERILSQLSQAKERI 412 HSP 2 Score: 132.109 bits (331), Expect = 8.646e-31 Identity = 113/412 (27.43%), Postives = 194/412 (47.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQG--TVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREW---GRPLACAITNFD---MASEAADRLLYQLPSFQETDMYRD-ITGESLNVLAN---EDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDK-WSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISEN 3157
P + W ++ Q TVFE+++ I ++LD E++FK+ P L + K E ++ + + K +LLD R LQ+ +I+ R+ + + A+ + +++E D L LP+ +E +Y T ES N + N +D VA L I+R+E KL + M FDE+ L+ + V A + E+Q +LE++LAFGN MN +RG A GF++ SLD L ++P D+ +L++ I IE+ P LK F +L++V+ A+ V ++ +EL+ G ++AE+ +K P L F ++ L + A +F E++GE + ++ SP +FF L F+ +++K EN
Sbjct: 621 PQLNWTAMKPMQAKNTVFEKLNDELIIEKLDFSKLEEMFKLAQ-------PTLGLAEPKS-EQSVIGQVSPGSTTSAAGTSSARKNTLLDTKR----------------LQNVAITRRKVAMDAKSIMAAVHQLNLSALSAEKVDILSRILPTDEERKLYAGKKTTESENSMENLSEDDNFVAALCEIERLEHKLAVMRVMSEFDESAGLLEPQFTHVTAASKCAREAQLFHGVLEVILAFGNYMNSGKRGGAYGFKLSSLDSLAILKAPADRSLTLLHMIVAEIEKNLPHLKTFSEQLKFVDKATSVQWDSVQTDMKELAAGF-KMAEKEQELKGTD------CPEALSTFTASRKQKMADLEQAFQLAASSFKDCCEFYGENE-KSTSPTVFFQKLAHFVQNYQKCRGEN 1000
BLAST of Formin-like protein vs. Ensembl Celegans
Match: frl-1 (FRL (Formin Related gene in Leukocytes) homolog [Source:UniProtKB/TrEMBL;Acc:Q9BL72]) HSP 1 Score: 154.066 bits (388), Expect = 1.436e-37 Identity = 108/338 (31.95%), Postives = 179/338 (52.96%), Query Frame = 2
Query: 317 QNAKQILSATEISLRTNHVEWVYDFLK--HSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIES-DFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQL 1321
+ + +L EISLRTN V+WV++FL + GL LVDYM +L S P T +G N + + + N S + SP N S ++ S + S S ++ + + K G+++ + +H+C+ C R I+NN++G Q F D I I ++H + +TK+L+L +LS++C ++GG E V AFD F+ RE +RF TLM F H ++++++ S +QF V+ V+++N RV+LQYE TLLGLD ++ + E D L ++ +Y +N +D LL+D+ K + E ER+ +S +E++
Sbjct: 91 ETSTSVLRHIEISLRTNSVDWVFEFLNTPNLGLRKLVDYMRTLLADCAPS-----VPSTSSGLPAGFLNSTANSSVGANNNHSSLNESPSHNSS----YEMSTTTTANTSNSFDATANLLKKGPLTISKGKVAKTTGEAVDD-IHICMMCLRAIMNNKQGFQQVFADTDAIYCIVRSILHQNLRTKTLVLQMLSSICWVQGGQELVSDAFDRFEKDFREPRRFWTLMQFVSHP-----PEFHVEFLSSAVQFFYYFVN-VDDLNFRVHLQYEMTLLGLDKYIDMMAECESDELQERMISYQNNGIDVQQLLDDSNQKTELLDENERILSQLSQAKERI 412 HSP 2 Score: 132.109 bits (331), Expect = 8.646e-31 Identity = 113/412 (27.43%), Postives = 194/412 (47.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQG--TVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREW---GRPLACAITNFD---MASEAADRLLYQLPSFQETDMYRD-ITGESLNVLAN---EDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDK-WSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISEN 3157
P + W ++ Q TVFE+++ I ++LD E++FK+ P L + K E ++ + + K +LLD R LQ+ +I+ R+ + + A+ + +++E D L LP+ +E +Y T ES N + N +D VA L I+R+E KL + M FDE+ L+ + V A + E+Q +LE++LAFGN MN +RG A GF++ SLD L ++P D+ +L++ I IE+ P LK F +L++V+ A+ V ++ +EL+ G ++AE+ +K P L F ++ L + A +F E++GE + ++ SP +FF L F+ +++K EN
Sbjct: 621 PQLNWTAMKPMQAKNTVFEKLNDELIIEKLDFSKLEEMFKLAQ-------PTLGLAEPKS-EQSVIGQVSPGSTTSAAGTSSARKNTLLDTKR----------------LQNVAITRRKVAMDAKSIMAAVHQLNLSALSAEKVDILSRILPTDEERKLYAGKKTTESENSMENLSEDDNFVAALCEIERLEHKLAVMRVMSEFDESAGLLEPQFTHVTAASKCAREAQLFHGVLEVILAFGNYMNSGKRGGAYGFKLSSLDSLAILKAPADRSLTLLHMIVAEIEKNLPHLKTFSEQLKFVDKATSVQWDSVQTDMKELAAGF-KMAEKEQELKGTD------CPEALSTFTASRKQKMADLEQAFQLAASSFKDCCEFYGENE-KSTSPTVFFQKLAHFVQNYQKCRGEN 1000
BLAST of Formin-like protein vs. Ensembl Celegans
Match: daam-1 (DAAM (Disheveled-Associated Activator of Morphogenesis) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASL6]) HSP 1 Score: 93.5893 bits (231), Expect = 6.993e-19 Identity = 103/412 (25.00%), Postives = 184/412 (44.66%), Query Frame = 2
Query: 1952 GDAPLIKWN--ILRNQQGTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNR-QKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRR-GKAIGFRIQSLDMLPECRSP--DDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENN-PDLIPTR-----LV--NFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEK-DLQTASPDLFFGALVRFMDSF 3136
G+ + W L +GTV++ ID +I KQLDL F + D DT+ G I R Q I+++DP R Q C M+ + K ++ +S E + + + +++L +P+ +E + + S VLA DR + +S I R E +L + + +F + AL I+ V A S ++++ ++IL I+LA GN +N +R G A GF + S++ L + ++ +D+ +L++++ IE+K+PDL F + V +A+R S A L L V +EL+L+++ + P+ IP LV F+ + + L + K F ++F P+ FF + +F+++F
Sbjct: 531 GNMKTLNWQRLTLDKTRGTVWDGIDDEKIYKQLDLTELSGCFAASSSHKDEDT---DTLYGT---INRR--------------PQQANITVIDPRRYQNCTIMLSKLKLSHKEIKQAMMSMDEKCK----------LPKDMIEQMLKFMPTKEELTQINESVQKHGSPTVLALADRYMYEISSIPRFEQRLRCLNIIRSFHDRVEALVPFIQVVLKATSSCQQNKRFRQILTIILAIGNYLNFGKRNGNAYGFEMASINKLADVKNALRNDR-NLLHFLVNFIEKKYPDLTKFKKDFATVTEAARFSQSETAAEIRNLEEALLIVRKELNLLESTTKVELPEHIPPENDRFALVAKAFIEKATAEYHNLDKMFREMKNKFSDCAKYFCYSPSGGVPVPEEFFSVINKFLNTF 911
BLAST of Formin-like protein vs. Ensembl Celegans
Match: daam-1 (DAAM (Disheveled-Associated Activator of Morphogenesis) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASL6]) HSP 1 Score: 93.5893 bits (231), Expect = 6.993e-19 Identity = 103/412 (25.00%), Postives = 184/412 (44.66%), Query Frame = 2
Query: 1952 GDAPLIKWN--ILRNQQGTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNR-QKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRR-GKAIGFRIQSLDMLPECRSP--DDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENN-PDLIPTR-----LV--NFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEK-DLQTASPDLFFGALVRFMDSF 3136
G+ + W L +GTV++ ID +I KQLDL F + D DT+ G I R Q I+++DP R Q C M+ + K ++ +S E + + + +++L +P+ +E + + S VLA DR + +S I R E +L + + +F + AL I+ V A S ++++ ++IL I+LA GN +N +R G A GF + S++ L + ++ +D+ +L++++ IE+K+PDL F + V +A+R S A L L V +EL+L+++ + P+ IP LV F+ + + L + K F ++F P+ FF + +F+++F
Sbjct: 531 GNMKTLNWQRLTLDKTRGTVWDGIDDEKIYKQLDLTELSGCFAASSSHKDEDT---DTLYGT---INRR--------------PQQANITVIDPRRYQNCTIMLSKLKLSHKEIKQAMMSMDEKCK----------LPKDMIEQMLKFMPTKEELTQINESVQKHGSPTVLALADRYMYEISSIPRFEQRLRCLNIIRSFHDRVEALVPFIQVVLKATSSCQQNKRFRQILTIILAIGNYLNFGKRNGNAYGFEMASINKLADVKNALRNDR-NLLHFLVNFIEKKYPDLTKFKKDFATVTEAARFSQSETAAEIRNLEEALLIVRKELNLLESTTKVELPEHIPPENDRFALVAKAFIEKATAEYHNLDKMFREMKNKFSDCAKYFCYSPSGGVPVPEEFFSVINKFLNTF 911
BLAST of Formin-like protein vs. Ensembl Celegans
Match: daam-1 (DAAM (Disheveled-Associated Activator of Morphogenesis) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3ASL6]) HSP 1 Score: 93.2041 bits (230), Expect = 7.436e-19 Identity = 104/412 (25.24%), Postives = 184/412 (44.66%), Query Frame = 2
Query: 1952 GDAPLIKWN--ILRNQQGTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNR-QKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRR-GKAIGFRIQSLDMLPECRSP--DDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENN-PDLIPTR-----LV--NFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEK-DLQTASPDLFFGALVRFMDSF 3136
G+ + W L +GTV++ ID +I KQLDL F + D DT+ G I R Q I+++DP R Q C M+ + K ++ +S E C + + +++L +P+ +E + + S VLA DR + +S I R E +L + + +F + AL I+ V A S ++++ ++IL I+LA GN +N +R G A GF + S++ L + ++ +D+ +L++++ IE+K+PDL F + V +A+R S A L L V +EL+L+++ + P+ IP LV F+ + + L + K F ++F P+ FF + +F+++F
Sbjct: 362 GNMKTLNWQRLTLDKTRGTVWDGIDDEKIYKQLDLTELSGCFAASSSHKDEDT---DTLYGT---INRR--------------PQQANITVIDPRRYQNCTIMLSKLKLSHKEIKQAMMSMDE-----KC-----KLPKDMIEQMLKFMPTKEELTQINESVQKHGSPTVLALADRYMYEISSIPRFEQRLRCLNIIRSFHDRVEALVPFIQVVLKATSSCQQNKRFRQILTIILAIGNYLNFGKRNGNAYGFEMASINKLADVKNALRNDR-NLLHFLVNFIEKKYPDLTKFKKDFATVTEAARFSQSETAAEIRNLEEALLIVRKELNLLESTTKVELPEHIPPENDRFALVAKAFIEKATAEYHNLDKMFREMKNKFSDCAKYFCYSPSGGVPVPEEFFSVINKFLNTF 742
BLAST of Formin-like protein vs. Ensembl Fly
Match: Frl (gene:FBgn0267795 transcript:FBtr0075776) HSP 1 Score: 201.83 bits (512), Expect = 2.931e-52 Identity = 143/457 (31.29%), Postives = 240/457 (52.52%), Query Frame = 2
Query: 11 MAMGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEF---QNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMS---QILLH-------LIKSEEMQIFPITMNGTNTI---------------SSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLE 1291
+ +Q Q P L+ S ++ P P ++ ++R+ + S+D+ P + + + +K +++ + E K HY++ ++ K + S RK + + Q+L EISLRTNH+EWV +FL + GL+ LVDY+S Q++ H L SEE +G + S+ STG ++ ++S + R A +S + + +N A D I + +CL R I+NN+ G M ++++ IN I + L+H S +TK+L+L+LL+A+CL++GGHE +L +FD FK + +E++RF TLM ++ + E +NID+ V+ MQF+NI+VHSVE++N RV+LQYEFT LGLD +L++++ + L Q+ AYLDN+ D + L+ED+E K + + + LE
Sbjct: 56 IGCSSQYQHVRQPSLR---SRSQQPMPTT-DELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYLSKLRTYLDPKASRSHRKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMG------------AATDDIHVSI-MCL---RAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQEKRRFQTLMEYFMNFEA-----FNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETKTSALERVQELE 487 HSP 2 Score: 174.096 bits (440), Expect = 1.335e-43 Identity = 127/414 (30.68%), Postives = 210/414 (50.72%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLN--DNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPL---ACAITNFDMAS---EAADRLLYQLPSFQETDMYRD--ITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARR 3166
P + W L+ Q GT+F E+D +I KQ+D + FE+ FK+ G G ++ N D L + D +SLL+ R + I +IS R+ G P+ AI + D+ E + L +P+ E Y++ I + +L ED+ + LS ++R+ KL + YM F ++ + +++++A A S+ +S+K K +LEIVLAFGN +N ++RG A GF++QSLD L + +S D + SL++YI I KFP+L NF SEL + A+ V+L N++A +EL G+D V +E L + + L +F+ + ++ +++ A+ AF + VE+FG+ + A FF +VRF +FK+ EN +R
Sbjct: 689 PTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKI----------------GIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNI----------------AISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHI------LRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSS-RNADAAAFFALIVRFTRAFKQHDQENEQR 1063
BLAST of Formin-like protein vs. Ensembl Fly
Match: Frl (gene:FBgn0267795 transcript:FBtr0334053) HSP 1 Score: 201.445 bits (511), Expect = 3.389e-52 Identity = 143/457 (31.29%), Postives = 240/457 (52.52%), Query Frame = 2
Query: 11 MAMGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEF---QNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMS---QILLH-------LIKSEEMQIFPITMNGTNTI---------------SSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLE 1291
+ +Q Q P L+ S ++ P P ++ ++R+ + S+D+ P + + + +K +++ + E K HY++ ++ K + S RK + + Q+L EISLRTNH+EWV +FL + GL+ LVDY+S Q++ H L SEE +G + S+ STG ++ ++S + R A +S + + +N A D I + +CL R I+NN+ G M ++++ IN I + L+H S +TK+L+L+LL+A+CL++GGHE +L +FD FK + +E++RF TLM ++ + E +NID+ V+ MQF+NI+VHSVE++N RV+LQYEFT LGLD +L++++ + L Q+ AYLDN+ D + L+ED+E K + + + LE
Sbjct: 56 IGCSSQYQHVRQPSLR---SRSQQPMPTT-DELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYLSKLRTYLDPKASRSHRKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMG------------AATDDIHVSI-MCL---RAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQEKRRFQTLMEYFMNFEA-----FNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETKTSALERVQELE 487 HSP 2 Score: 174.096 bits (440), Expect = 1.144e-43 Identity = 127/414 (30.68%), Postives = 210/414 (50.72%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLN--DNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPL---ACAITNFDMAS---EAADRLLYQLPSFQETDMYRD--ITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARR 3166
P + W L+ Q GT+F E+D +I KQ+D + FE+ FK+ G G ++ N D L + D +SLL+ R + I +IS R+ G P+ AI + D+ E + L +P+ E Y++ I + +L ED+ + LS ++R+ KL + YM F ++ + +++++A A S+ +S+K K +LEIVLAFGN +N ++RG A GF++QSLD L + +S D + SL++YI I KFP+L NF SEL + A+ V+L N++A +EL G+D V +E L + + L +F+ + ++ +++ A+ AF + VE+FG+ + A FF +VRF +FK+ EN +R
Sbjct: 689 PTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKI----------------GIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNI----------------AISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHI------LRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSS-RNADAAAFFALIVRFTRAFKQHDQENEQR 1063
BLAST of Formin-like protein vs. Ensembl Fly
Match: Frl (gene:FBgn0267795 transcript:FBtr0114573) HSP 1 Score: 201.83 bits (512), Expect = 3.518e-52 Identity = 143/457 (31.29%), Postives = 240/457 (52.52%), Query Frame = 2
Query: 11 MAMGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEF---QNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMS---QILLH-------LIKSEEMQIFPITMNGTNTI---------------SSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLE 1291
+ +Q Q P L+ S ++ P P ++ ++R+ + S+D+ P + + + +K +++ + E K HY++ ++ K + S RK + + Q+L EISLRTNH+EWV +FL + GL+ LVDY+S Q++ H L SEE +G + S+ STG ++ ++S + R A +S + + +N A D I + +CL R I+NN+ G M ++++ IN I + L+H S +TK+L+L+LL+A+CL++GGHE +L +FD FK + +E++RF TLM ++ + E +NID+ V+ MQF+NI+VHSVE++N RV+LQYEFT LGLD +L++++ + L Q+ AYLDN+ D + L+ED+E K + + + LE
Sbjct: 56 IGCSSQYQHVRQPSLR---SRSQQPMPTT-DELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYLSKLRTYLDPKASRSHRKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMG------------AATDDIHVSI-MCL---RAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQEKRRFQTLMEYFMNFEA-----FNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETKTSALERVQELE 487 HSP 2 Score: 174.096 bits (440), Expect = 1.558e-43 Identity = 127/414 (30.68%), Postives = 210/414 (50.72%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLN--DNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPL---ACAITNFDMAS---EAADRLLYQLPSFQETDMYRD--ITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARR 3166
P + W L+ Q GT+F E+D +I KQ+D + FE+ FK+ G G ++ N D L + D +SLL+ R + I +IS R+ G P+ AI + D+ E + L +P+ E Y++ I + +L ED+ + LS ++R+ KL + YM F ++ + +++++A A S+ +S+K K +LEIVLAFGN +N ++RG A GF++QSLD L + +S D + SL++YI I KFP+L NF SEL + A+ V+L N++A +EL G+D V +E L + + L +F+ + ++ +++ A+ AF + VE+FG+ + A FF +VRF +FK+ EN +R
Sbjct: 689 PTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKI----------------GIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNI----------------AISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHI------LRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSS-RNADAAAFFALIVRFTRAFKQHDQENEQR 1063
BLAST of Formin-like protein vs. Ensembl Fly
Match: Frl (gene:FBgn0267795 transcript:FBtr0075775) HSP 1 Score: 196.052 bits (497), Expect = 2.442e-50 Identity = 143/466 (30.69%), Postives = 239/466 (51.29%), Query Frame = 2
Query: 11 MAMGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEF------------QNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMS---QILLH-------LIKSEEMQIFPITMNGTNTI---------------SSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLE 1291
+ +Q Q P L+ S ++ P P ++ ++R+ + S+D+ P + + + +K +++ + E K HY++ ++ K + S R F + Q+L EISLRTNH+EWV +FL + GL+ LVDY+S Q++ H L SEE +G + S+ STG ++ ++S + R A +S + + +N A D I + +CL R I+NN+ G M ++++ IN I + L+H S +TK+L+L+LL+A+CL++GGHE +L +FD FK + +E++RF TLM ++ + E +NID+ V+ MQF+NI+VHSVE++N RV+LQYEFT LGLD +L++++ + L Q+ AYLDN+ D + L+ED+E K + + + LE
Sbjct: 56 IGCSSQYQHVRQPSLR---SRSQQPMPTT-DELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYLSKLRTYLDPKASRSHRLYLFYFLCQKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMG------------AATDDIHVSI-MCL---RAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQEKRRFQTLMEYFMNFEA-----FNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETKTSALERVQELE 496 HSP 2 Score: 174.096 bits (440), Expect = 1.527e-43 Identity = 127/414 (30.68%), Postives = 210/414 (50.72%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLN--DNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPL---ACAITNFDMAS---EAADRLLYQLPSFQETDMYRD--ITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARR 3166
P + W L+ Q GT+F E+D +I KQ+D + FE+ FK+ G G ++ N D L + D +SLL+ R + I +IS R+ G P+ AI + D+ E + L +P+ E Y++ I + +L ED+ + LS ++R+ KL + YM F ++ + +++++A A S+ +S+K K +LEIVLAFGN +N ++RG A GF++QSLD L + +S D + SL++YI I KFP+L NF SEL + A+ V+L N++A +EL G+D V +E L + + L +F+ + ++ +++ A+ AF + VE+FG+ + A FF +VRF +FK+ EN +R
Sbjct: 698 PTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKI----------------GIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNI----------------AISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHI------LRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSS-RNADAAAFFALIVRFTRAFKQHDQENEQR 1072
BLAST of Formin-like protein vs. Ensembl Fly
Match: DAAM (gene:FBgn0025641 transcript:FBtr0070241) HSP 1 Score: 134.42 bits (337), Expect = 2.377e-31 Identity = 113/400 (28.25%), Postives = 193/400 (48.25%), Query Frame = 2
Query: 1973 WNILRNQ--QGTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKW-SLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNA--VENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISEN 3157
W+ L + QGTV+ E+D S++ ++L+ +K+F Y + DG + D +++G A + +S++D R + ++++ L +S E + + +N + + ++LL PS +E + D E + LA DR + +S I E +L+++ Y F T L +I +V A R V S++L+K+LE+VLA GN MN RG A GFR+ SL+ L + +S K +L++Y+ IE KF DL ++ +V +AS+VSL + + L TGL VA E+ +++ + +P + F + R L ++ + K F + V FGE D PD FFG F+ +F +A +N
Sbjct: 616 WSKLPDAKLQGTVWSELDESKLYNNMELESIDKLFSA------YQKNGVSATDG---------SYEDLRVTGKAAKQKV--LSVIDGRRAQNCTILLSKL---------KMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALL-DEHSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPV-MREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGE-DGSVLQPDEFFGIFDSFLAAFAEARHDN 986 HSP 2 Score: 83.9593 bits (206), Expect = 7.303e-16 Identity = 52/168 (30.95%), Postives = 87/168 (51.79%), Query Frame = 2
Query: 737 LHLCL-KCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLM-------YFYRHHETLPLDDYNIDYAVSNMQFINIIVH---SVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAY 1207
LH L C + ++NN G + I+ I L + +TK L++L AVCL+ GGH +VL+A F+V E RF +++ Y YR D+ N+ A+ M F+N +++ EN+ R++L+YEF +LG+ + KL+ + L+R +D +
Sbjct: 144 LHTSLIGCIKALMNNSMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLVPGGHRKVLQAMLHFQVFATERTRFQSIVNDLDRSTYAYR-------DNVNLKTAL--MSFVNAVLNYGPGQENLEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFF 302
BLAST of Formin-like protein vs. Ensembl Zebrafish
Match: fmnl3 (formin-like 3 [Source:NCBI gene;Acc:407694]) HSP 1 Score: 221.476 bits (563), Expect = 3.678e-62 Identity = 166/509 (32.61%), Postives = 275/509 (54.03%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIES--DFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDL 1522
MGN + +K+ + P P E E+R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++G K+T K + Q + ++L EISLRTNH+ WV +FL ++ GL+ILV+Y+S + + G+E+ DFS +S R + +N +R S + ++S SK K+ V S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E+ RF+ LM ++R +D NID+ V+ MQFINI+VHSVE++N RV+LQYEFT LGLD FL+K + D+L+ Q+ AYLDN+ D LLEDAE K + + E LE+ +S + E+L E E K+ + E ++ +KEL + + S V +LR I++ + R +++++++ +L
Sbjct: 1 MGNIESVDGQSEMKHHIMPLKVPMPDPTE-LEERFAIVLNSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLRGYLDPKVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENRGLDILVEYLS----------------------------FAQCAVMLDFEGLENGEDFSLDKAKSWSRSIEDLHQNGCNTLVRSARQSVLRYGSTSNSKTIKNSRLV--SQKDDVHVCIMCLRAIMNYQYGFNLVMSHAHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCKEKHRFEKLMEYFRS------EDGNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLDDFLEKSKHTESDKLSVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHLSHVTEKLLDVENETMTKVADLEKQLLHKDKELAVIKETYESASTQVHTLRRMIQEKDAAFQ-RHNNIEKQLLEL 468
BLAST of Formin-like protein vs. Ensembl Zebrafish
Match: fmnl2a (formin-like 2a [Source:ZFIN;Acc:ZDB-GENE-081105-70]) HSP 1 Score: 227.254 bits (578), Expect = 2.779e-60 Identity = 175/514 (34.05%), Postives = 278/514 (54.09%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P+ E E+R+ + + S+++ P + + Q + +K EL+ + F+ KNP + H L+SY +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + +T +G + SEN E+ S R I D N S S S NR+++ S S + +S C +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + EE+RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT LGLD +L KL+ D+L+ Q+ AYLDN+ D LLEDAE K A + E LE+++S L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + + R+ +++++I +L Q G I ++KK
Sbjct: 23 PMPEPAE-LEERFALVLNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHTYIH------KLQSYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-----------FAQYAVTYDGDS-------------SENSTENSVDKSKAWS-RSIEDLHGGNHLSSGGSGSNISRTNRHSTIRSNTLPSRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDHFKEVCLEEQRFEKLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLGLDEYLDKLKHTESDKLHVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLTEKLQDTENEAMAKIVELEKQLMQRNKELDSLRDVYKDANSQVHTLRRMVKEKDEAIQ-RQCNLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 167.548 bits (423), Expect = 1.590e-41 Identity = 131/413 (31.72%), Postives = 214/413 (51.82%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE++FK P +D K Q+ KISLLD NR K + +I+ R+ G+ + I FD+ + D L+ +PS E + R E L L +EDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA +++K+ + F++EL YVE A+ VSL N++ +EL G+D +E S+ + T L +F+++N ++ L++ + A+ AF + V++FGE + +T P +FF VRF+ ++++A +N +++
Sbjct: 624 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKTKA-----QGPAIDITSSKQKTAQK----------------GPHKISLLDANRSKNL----------------AITLRKVGKTSEEICRGIQLFDLRTLPVDFVECLMRFIPSEAELKVLRQYEKERKPLENLTDEDRFMIQFSKIERLMQKMTIMAFVGNFTESIQMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKITLLHYIANVVKDKYQQVSLFYNELNYVEKAAAVSLENVLLDVKELQRGMDLTRKEYSMHGHN---------TLLKDFIQQNENKLKKLQDDAKIAQDAFDEVVKFFGE-NAKTTPPSVFFPVFVRFVKAYRQAEEDNEQKK 989
BLAST of Formin-like protein vs. Ensembl Zebrafish
Match: fmnl2a (formin-like 2a [Source:ZFIN;Acc:ZDB-GENE-081105-70]) HSP 1 Score: 227.254 bits (578), Expect = 3.174e-60 Identity = 175/514 (34.05%), Postives = 278/514 (54.09%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P+ E E+R+ + + S+++ P + + Q + +K EL+ + F+ KNP + H L+SY +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + +T +G + SEN E+ S R I D N S S S NR+++ S S + +S C +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + EE+RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT LGLD +L KL+ D+L+ Q+ AYLDN+ D LLEDAE K A + E LE+++S L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + + R+ +++++I +L Q G I ++KK
Sbjct: 23 PMPEPAE-LEERFALVLNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHTYIH------KLQSYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-----------FAQYAVTYDGDS-------------SENSTENSVDKSKAWS-RSIEDLHGGNHLSSGGSGSNISRTNRHSTIRSNTLPSRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDHFKEVCLEEQRFEKLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLGLDEYLDKLKHTESDKLHVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLTEKLQDTENEAMAKIVELEKQLMQRNKELDSLRDVYKDANSQVHTLRRMVKEKDEAIQ-RQCNLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 170.629 bits (431), Expect = 1.869e-42 Identity = 147/500 (29.40%), Postives = 244/500 (48.80%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ------MGDXXXXXXXXXXXXXXPKGDQTRKKN------RTRQI--------NADGIMDEIMAGLDYQPLQAGLHARRGKRDNTDSP 3370
P+ W L+ Q GTVF EID +I + L++D FE++FK + P +D K Q+ KISLLD NR K + +I+ R+ G+ + I FD+ + D L+ +PS E + R E L L +EDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA +++K+ + F++EL YVE A+ VSL N++ +EL G+D +E S+ + T L +F+++N ++ L++ + A+ AF + V++FGE + +T P +FF VRF+ ++++A +N +++ M ++ ++ P R++ R +Q+ DG +++I+ L QP + RR R D P
Sbjct: 624 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----KAQGPAIDITSSKQKTAQK----------------GPHKISLLDANRSKNL----------------AITLRKVGKTSEEICRGIQLFDLRTLPVDFVECLMRFIPSEAELKVLRQYEKERKPLENLTDEDRFMIQFSKIERLMQKMTIMAFVGNFTESIQMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKITLLHYIANVVKDKYQQVSLFYNELNYVEKAAAVSLENVLLDVKELQRGMDLTRKEYSMHGHN---------TLLKDFIQQNENKLKKLQDDAKIAQDAFDEVVKFFGE-NAKTTPPSVFFPVFVRFVKAYRQAEEDNEQKKRHEQMMMEKLIEQEAMEQEDQKSPSHKNKRQQQELIAELRKKQVKDSRHVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFDDP 1076
BLAST of Formin-like protein vs. Ensembl Zebrafish
Match: fmnl3 (formin-like 3 [Source:NCBI gene;Acc:407694]) HSP 1 Score: 226.483 bits (576), Expect = 4.058e-60 Identity = 171/532 (32.14%), Postives = 283/532 (53.20%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIES--DFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKP 1591
MGN + +K+ + P P E E+R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++G K+T K + Q + ++L EISLRTNH+ WV +FL ++ GL+ILV+Y+S + + G+E+ DFS +S R + +N +R S + ++S SK K+ V S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E+ RF+ LM ++R +D NID+ V+ MQFINI+VHSVE++N RV+LQYEFT LGLD FL+K + D+L+ Q+ AYLDN+ D LLEDAE K + + E LE+ +S + E+L E E K+ + E ++ +KEL + + S V +LR I++ + R +++++++ +L Q G I ++K+P
Sbjct: 1 MGNIESVDGQSEMKHHIMPLKVPMPDPTE-LEERFAIVLNSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLRGYLDPKVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENRGLDILVEYLS----------------------------FAQCAVMLDFEGLENGEDFSLDKAKSWSRSIEDLHQNGCNTLVRSARQSVLRYGSTSNSKTIKNSRLV--SQKDDVHVCIMCLRAIMNYQYGFNLVMSHAHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCKEKHRFEKLMEYFRS------EDGNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLDDFLEKSKHTESDKLSVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHLSHVTEKLLDVENETMTKVADLEKQLLHKDKELAVIKETYESASTQVHTLRRMIQEKDAAFQ-RHNNIEKQLLELE-----------QQGTIRLRKQP 480 HSP 2 Score: 201.445 bits (511), Expect = 4.076e-52 Identity = 155/493 (31.44%), Postives = 250/493 (50.71%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXXXXXXXXXX--PKGDQTRKKNRTRQINA-----------------DGIMDEIMAGLDYQPLQAGLHARRGKR 3352
P+ W L+ Q GTVF EID ++ ++LDL+ FE++FK P +D K Q+ N K+ LLD NR K + +I+ R+ + + AI FD+ + D L+ LP+ E+ + R E L+ LA EDR + L S I+R+ ++ I ++ F++ L ++ + A SV S KLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA ++EK+P+L NF++EL +V+ A+ VSL N++ +EL G+D V E SL +AV L F + + T+++ L + A+ AF V +FGE +T P +FF VRF+ ++K+A+ EN +R+ +E R+K ++ + PK +K+++ +++ A DG +++I+ L P A A+RG R
Sbjct: 591 PVFNWTALKPNQINGTVFNEIDDDRVLEELDLEKFEELFKTKA-----QGPVVDLSCSKSKVSQKVIN----------------KVQLLDANRSKNL----------------AITLRKANKTTEEICKAIQTFDLKALPVDFVECLMRFLPTEAESKLLRQYERERRPLDQLAEEDRFMLLFSKIERLTQRMSIITFVGNFNDNVNMLTPQLNAIIAASASVKSSPKLKKILEIILALGNYMNSSKRGSVYGFKLQSLDLLLDTKSTDRKMTLLHYIALVVKEKYPELANFYNELHFVDKAAAVSLENVLLDVKELGKGMDLVRRECSLHDHAV----------LKGFAQTSDTQLDKLAKDAKTAEEAFNNVVLYFGESP-KTTPPSVFFPVFVRFIRAYKEAVEENEQRKKQEEAMREKLLAQEAKQHDPKVQAQKKRHQQQELIAELRRRQAKDHRPVYEGKDGTIEDIITVLKSVPFTART-AKRGSR 1034
BLAST of Formin-like protein vs. Ensembl Zebrafish
Match: fmnl2b (formin-like 2b [Source:ZFIN;Acc:ZDB-GENE-041111-182]) HSP 1 Score: 222.246 bits (565), Expect = 1.408e-58 Identity = 170/511 (33.27%), Postives = 277/511 (54.21%), Query Frame = 2
Query: 32 QGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIE-----SDF-SPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDL 1522
+GS P+L P P LE+ R+ + + ++++ P ++ + Q + +K EL+ + F+ KNP T I+ LRS+ +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + +T +G S+ + + T IE S+ SP + S+ R S R+ NT + K+ V K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E +RF+ LM +++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L++L+ D+L Q+ AYLDNL D LLEDAE K A + E LE+++S + ++L E E KI E E ++ + KEL+ ++ + S V +LR +R+ + + ++S ++++I +L
Sbjct: 17 RGSKPPKLPM-------PDPAELEE---RFAIALNTMNLPPDKVRILRQYDNEKKWELICDQERFQVKNPPH------TYIQKLRSFLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-----------FAQYAVTFDGDVAESATGEISVETPWSRSIEDLHGDSNLPSPVSGSSIPRSTRHSLRS----------------NTLPSRRTLKNSRLVCK--KDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDHFKEVCSETQRFEKLMEHFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLSLDDYLERLKHTESDKLKVQIQAYLDNLFDVGTLLEDAETKNAALERVEELEENLSHMSDKLLETENEAMSKIVELEKQLMQKNKELDTVRAVYRDASSQVHTLRRIVREKDETIQ-KQSTLEKKIHEL 475 HSP 2 Score: 189.889 bits (481), Expect = 1.747e-48 Identity = 133/413 (32.20%), Postives = 213/413 (51.57%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE++FK + P +D L + G N K+SLL+ NR K + +I+ R+ G+ + AI FD+ + D L+ +P+ E + R E ++ L +EDR + L S I+R+ ++ + +M F ++ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L E +S D K +L++YIA ++EK+P + F++EL Y+E A+ VSL N++ EL G+D E S+ + + L +F+ N R+ L + + A+ AF + V++FGE +T P +FF VRF+ S+++A EN R+
Sbjct: 644 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----KAQGPAVDM------------TLQKQKAPQKGPN----KVSLLEANRAKNL----------------AITLRKAGKSPEEICKAIQTFDLRTVPVDFVECLMRFMPTESEVKVLRQYERERRPMDGLTDEDRFMMLFSKIERLPQRMTIMAFMGNFTDSLQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLETKSTDRKQTLLHYIANVVKEKYPIVSIFYNELHYIEKAAAVSLENVLLDVRELQRGMDLTKREYSMHGHN---------SLLKDFIHHNEARLKKLLDDAKIAQDAFDEAVKFFGE-SAKTMPPSVFFPVFVRFIKSYRQADEENELRK 1009
BLAST of Formin-like protein vs. Ensembl Xenopus
Match: fmnl1 (formin like 1 [Source:NCBI gene;Acc:493573]) HSP 1 Score: 229.565 bits (584), Expect = 9.659e-61 Identity = 168/507 (33.14%), Postives = 267/507 (52.66%), Query Frame = 2
Query: 20 GNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNS---KRKDEFQNAKQILSATEISLRTNHVEWVYDFLKH--SGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDS-IKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREI 1513
G G+P P+ + + ++ P P ++E E+R+ V + ++++ P IQ + Q + +K EL+ + F+ KNP + I+ LRSY T K K Q + Q+L EISLRTNH+ WV +FL GL+ LV+Y+S FPI S+NG +P+ ++SL+R + ++S+ S + + S N + + +K+ +H+C+ C R I+N Q G M + +N IT+ L + + +TK+L+L+LL+AVCL+ GGHE +L AF+ F M E RF+ LM ++R +D NID+ V+ MQFINI+VHSV+N+N RV+LQYEFTLLGLD +L+ L+ +RL Q+ AYLDN+ D + LLED + K + E L++ ++ + E+L L E RV + EK+L++ + E+S E L + + N+ R +KR +
Sbjct: 18 GQSTSGTP-PQKQKEGTPSKLPRPNSVE-LEQRFNVVLNAMNLPPDKIQVLRQYDQDKKWELVCDQERFQVKNPPAA------YIQKLRSYLDTGGISRKFKRRVQESTQVLRELEISLRTNHIGWVEEFLSPEVGGLDALVEYLSYA---------QGSFPI---------------DTECSDNG-----TPEKSKSLQRSLEDINKSSSSPSPTNTPSRSRNLTARYNLHSRSTMRNTKHANMKDDVHVCIMCLRAIMNYQSGFSMVMSHSSCVNKITLSLSNKNPRTKALVLELLAAVCLVRGGHELILSAFNYFMEMCGEGARFEKLMEYFR------TEDSNIDFMVACMQFINIVVHSVKNMNFRVFLQYEFTLLGLDEYLEILKNTESERLQVQIQAYLDNIFDVNSLLEDTDTKNEMLEHVEDLQEHLTRVTEKLQL-------TENEYVRRVAELEKQLDQCRR---EMSSAKEKLVVQAPQVTQNIVQRTELVKRSV 471 HSP 2 Score: 159.458 bits (402), Expect = 9.297e-39 Identity = 120/405 (29.63%), Postives = 201/405 (49.63%), Query Frame = 2
Query: 1964 LIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWG---RPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITG------ESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKA 3145
++ W L+ Q GTVF ++ ++ ++LD+ FE+ FK + P T K A +Q +K+SL++ NR K + +I+ R+ G + AI +DM + D L L F TD R + L+ L EDR + L I R+ ++ + +M F + L+ ++ + A S+ S KLK ILE+VLAFGN MN S+RG A GFR+QSLD+L E +S D K +L++Y+ I EK+ L NF+ +L +++ A+ VSL +++A + L G+++V +E + + + LI L +F++ N+ + + + A+ A+ V +FGE + +T P FF VRF+ ++K+A
Sbjct: 698 VLNWVALKPTQINGTVFTHLNDEKVLQELDMSDFEENFKT-----KAQGPSQTTFSMK----------------VKAAQNQPNKVSLIETNRAKNL----------------AITLRKGGLSPEAITSAIQKYDMQAFNMD-FLELLARFLPTDWERQQISRYCRDQKPLDDLTAEDRFMVHLCSIPRLAERVNTMTFMANFPDMASRLKPQLDALIAASMSIKSSDKLKGILELVLAFGNYMNSSKRGAAYGFRLQSLDVLLETKSTDRKQTLLHYMIRVICEKYSHLSNFYCDLNFMDKAATVSLDSVLADVKSLQAGMEQVQKEFT------KQDDCLI---LKDFIKSNMDSLKQMSADAKTAQEAYDAAVGYFGE-NAKTTPPSTFFPIFVRFIKAYKQA 1054
BLAST of Formin-like protein vs. Ensembl Xenopus
Match: fmnl1 (formin like 1 [Source:NCBI gene;Acc:493573]) HSP 1 Score: 229.18 bits (583), Expect = 1.318e-60 Identity = 168/507 (33.14%), Postives = 267/507 (52.66%), Query Frame = 2
Query: 20 GNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNS---KRKDEFQNAKQILSATEISLRTNHVEWVYDFLKH--SGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDS-IKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREI 1513
G G+P P+ + + ++ P P ++E E+R+ V + ++++ P IQ + Q + +K EL+ + F+ KNP + I+ LRSY T K K Q + Q+L EISLRTNH+ WV +FL GL+ LV+Y+S FPI S+NG +P+ ++SL+R + ++S+ S + + S N + + +K+ +H+C+ C R I+N Q G M + +N IT+ L + + +TK+L+L+LL+AVCL+ GGHE +L AF+ F M E RF+ LM ++R +D NID+ V+ MQFINI+VHSV+N+N RV+LQYEFTLLGLD +L+ L+ +RL Q+ AYLDN+ D + LLED + K + E L++ ++ + E+L L E RV + EK+L++ + E+S E L + + N+ R +KR +
Sbjct: 18 GQSTSGTP-PQKQKEGTPSKLPRPNSVE-LEQRFNVVLNAMNLPPDKIQVLRQYDQDKKWELVCDQERFQVKNPPAA------YIQKLRSYLDTGGISRKFKRRVQESTQVLRELEISLRTNHIGWVEEFLSPEVGGLDALVEYLSYA---------QGSFPI---------------DTECSDNG-----TPEKSKSLQRSLEDINKSSSSPSPTNTPSRSRNLTARYNLHSRSTMRNTKHANMKDDVHVCIMCLRAIMNYQSGFSMVMSHSSCVNKITLSLSNKNPRTKALVLELLAAVCLVRGGHELILSAFNYFMEMCGEGARFEKLMEYFR------TEDSNIDFMVACMQFINIVVHSVKNMNFRVFLQYEFTLLGLDEYLEILKNTESERLQVQIQAYLDNIFDVNSLLEDTDTKNEMLEHVEDLQEHLTRVTEKLQL-------TENEYVRRVAELEKQLDQCRR---EMSSAKEKLVVQAPQVTQNIVQRTELVKRSV 471 HSP 2 Score: 159.458 bits (402), Expect = 9.790e-39 Identity = 120/405 (29.63%), Postives = 201/405 (49.63%), Query Frame = 2
Query: 1964 LIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWG---RPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITG------ESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKA 3145
++ W L+ Q GTVF ++ ++ ++LD+ FE+ FK + P T K A +Q +K+SL++ NR K + +I+ R+ G + AI +DM + D L L F TD R + L+ L EDR + L I R+ ++ + +M F + L+ ++ + A S+ S KLK ILE+VLAFGN MN S+RG A GFR+QSLD+L E +S D K +L++Y+ I EK+ L NF+ +L +++ A+ VSL +++A + L G+++V +E + + + LI L +F++ N+ + + + A+ A+ V +FGE + +T P FF VRF+ ++K+A
Sbjct: 711 VLNWVALKPTQINGTVFTHLNDEKVLQELDMSDFEENFKT-----KAQGPSQTTFSMK----------------VKAAQNQPNKVSLIETNRAKNL----------------AITLRKGGLSPEAITSAIQKYDMQAFNMD-FLELLARFLPTDWERQQISRYCRDQKPLDDLTAEDRFMVHLCSIPRLAERVNTMTFMANFPDMASRLKPQLDALIAASMSIKSSDKLKGILELVLAFGNYMNSSKRGAAYGFRLQSLDVLLETKSTDRKQTLLHYMIRVICEKYSHLSNFYCDLNFMDKAATVSLDSVLADVKSLQAGMEQVQKEFT------KQDDCLI---LKDFIKSNMDSLKQMSADAKTAQEAYDAAVGYFGE-NAKTTPPSTFFPIFVRFIKAYKQA 1067
BLAST of Formin-like protein vs. Ensembl Xenopus
Match: gclm (glutamate-cysteine ligase, modifier subunit [Source:Xenbase;Acc:XB-GENE-1014945]) HSP 1 Score: 221.476 bits (563), Expect = 2.318e-58 Identity = 171/513 (33.33%), Postives = 271/513 (52.83%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMN------GTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG + K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + K Q P + + G+N S G +I+ +G S S R + +N+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V+ MQFINI+VHSVE++N RV+LQ+EFT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ A+ + + V +LR +++ + R+S ++R+I +L Q G+I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVPRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-FAQYAGKKTWKQSLPWSRSIEDLHRGSNLPSP----VGNSITRSGRHSTLRYNTLPSRRTL----------------------KNSRLV------------SKKDDVHVCIMCLRAIMNYQYGFNMVMSHLHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQFEFTKLALDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMAKIVELEKQLMQRNKELDIAREVCKDANTQVHTLRKMVKEKEEAIQ-RQSTLERKIHELEKQ-----------GSIKIQKK 475 HSP 2 Score: 160.614 bits (405), Expect = 3.525e-39 Identity = 125/413 (30.27%), Postives = 211/413 (51.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + +++D FE+IFK G ++I + A + K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ +P+ E ++R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ + +K+ + F++E+ YVE A+ VSL N++ +EL G+D E ++ + V L F++ + R+ L++ + ++ AF V++FGE + +T P +FF VRF+ ++K A EN R+
Sbjct: 605 PVFNWVALKPHQINGTVFNEIDDERILEDINVDEFEEIFKT-------------KAQGPAIDISSTKQ--------KAAPKVTSKVTLLEANRAKNL----------------AITLRKAGKTAEEICKAIQLFDLKTLPVDFVECLMRFMPTEGEVKVFRQYEREKKPLENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFSESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVRDKYLQVALFYNEIHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHNV---------MLKEFIQNSEVRLKKLQDDAKISQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKNADEENEMRK 970
BLAST of Formin-like protein vs. Ensembl Xenopus
Match: cat.1 (catalase, gene 1 [Source:Xenbase;Acc:XB-GENE-5918489]) HSP 1 Score: 209.534 bits (532), Expect = 1.119e-54 Identity = 146/444 (32.88%), Postives = 236/444 (53.15%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKH--SGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISE----NGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQL 1321
MGN + P P P LE+ R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++ +T K + Q + ++L EISLRTNH+ WV +FL + GL++LV+Y+S + M F NG + + + +I + N + + F+ +S R+ S + NT K K+ V S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E RF+ LM ++R+ +D NID+ V+ MQFINI+VHSVE++N RV+LQ+EFT LGL+ FL+K + ++L Q+ AYLDN+ D LLEDAE K + + E LE+ +S + E+L
Sbjct: 1 MGNAESAGGPPGTALLPLKVPMPEPGELEE---RFAMVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLQSFLDPGVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNNDNKGLDVLVEYLS-----FAQCAVMFDFEGLENGEDGLVEKSKPWSRSIEDLQHPNSLPTPFANGLARSARQ-------------------SVLRYNTLPGKKALKNSRLV--SQKDDVHVCIMCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCKETHRFEKLMEYFRN------EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQFEFTKLGLEDFLEKAKHTESEKLLVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEQLSHMTEKL 406 HSP 2 Score: 187.193 bits (474), Expect = 1.192e-47 Identity = 131/413 (31.72%), Postives = 210/413 (50.85%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF ++D +I + LD+D FE++FK + P +D K QR + K++LL+ NR K + +I+ R+ GR + AI FD+ + D L+ LP+ E + R E L L++EDR + L S ++R+ ++ + ++ F+E L ++ V A SV S KLK++LE++LA GN MN S+RG GF++QSLD+L + +S D K +L+NYIA +EK+ ++ F++EL +VE A+ VSL N++ +EL G+D + +E N T L NFV N +++ L+ A+ A+ V +FGE + +T P +FF RF+ S+K+A EN R+
Sbjct: 553 PVFNWTALKPNQISGTVFNDLDDERILQDLDMDKFEELFKT-----KAQGPAIDLTCPKNKTSQR----------------SASKVTLLEANRAKNL----------------AITLRKAGRSSEEICKAIQTFDLRTLPVDFVECLVRFLPTEAEVKLLRQYERERKPLEDLSDEDRFMMLFSKVERLSQRMSIMTFLGNFNENLQLLTPQLNAVIAASVSVKSSPKLKQMLEVILALGNYMNSSKRGSVYGFKLQSLDLLQDTKSTDRKLTLLNYIALIAKEKYSEVATFYNELHFVEKAAAVSLENVLLDVKELGKGMDLIRKESHHHDN----------TFLRNFVSSNEGKLDKLQKDARTAEEAYAAVVLYFGE-NPKTTPPSVFFPVFARFIKSYKEAELENEMRK 917
BLAST of Formin-like protein vs. Ensembl Xenopus
Match: cat.1 (catalase, gene 1 [Source:Xenbase;Acc:XB-GENE-5918489]) HSP 1 Score: 209.149 bits (531), Expect = 1.597e-54 Identity = 146/444 (32.88%), Postives = 236/444 (53.15%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKH--SGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISE----NGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQL 1321
MGN + P P P LE+ R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++ +T K + Q + ++L EISLRTNH+ WV +FL + GL++LV+Y+S + M F NG + + + +I + N + + F+ +S R+ S + NT K K+ V S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E RF+ LM ++R+ +D NID+ V+ MQFINI+VHSVE++N RV+LQ+EFT LGL+ FL+K + ++L Q+ AYLDN+ D LLEDAE K + + E LE+ +S + E+L
Sbjct: 1 MGNAESAGGPPGTALLPLKVPMPEPGELEE---RFAMVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLQSFLDPGVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNNDNKGLDVLVEYLS-----FAQCAVMFDFEGLENGEDGLVEKSKPWSRSIEDLQHPNSLPTPFANGLARSARQ-------------------SVLRYNTLPGKKALKNSRLV--SQKDDVHVCIMCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCKETHRFEKLMEYFRN------EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQFEFTKLGLEDFLEKAKHTESEKLLVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEQLSHMTEKL 406 HSP 2 Score: 187.193 bits (474), Expect = 1.379e-47 Identity = 153/506 (30.24%), Postives = 247/506 (48.81%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXXXXXXXXXX--PKGDQTRKKN---------RTRQI--------NADGIMDEIMAGLDYQPLQAGLHARRGKRDNTDSPETSIYQE 3391
P+ W L+ Q GTVF ++D +I + LD+D FE++FK + P +D K QR + K++LL+ NR K + +I+ R+ GR + AI FD+ + D L+ LP+ E + R E L L++EDR + L S ++R+ ++ + ++ F+E L ++ V A SV S KLK++LE++LA GN MN S+RG GF++QSLD+L + +S D K +L+NYIA +EK+ ++ F++EL +VE A+ VSL N++ +EL G+D + +E N T L NFV N +++ L+ A+ A+ V +FGE + +T P +FF RF+ S+K+A EN R+ +E R+K ++ + PK + K R RQ DG +++I+ L P A A+RG R D TS++++
Sbjct: 576 PVFNWTALKPNQISGTVFNDLDDERILQDLDMDKFEELFKT-----KAQGPAIDLTCPKNKTSQR----------------SASKVTLLEANRAKNL----------------AITLRKAGRSSEEICKAIQTFDLRTLPVDFVECLVRFLPTEAEVKLLRQYERERKPLEDLSDEDRFMMLFSKVERLSQRMSIMTFLGNFNENLQLLTPQLNAVIAASVSVKSSPKLKQMLEVILALGNYMNSSKRGSVYGFKLQSLDLLQDTKSTDRKLTLLNYIALIAKEKYSEVATFYNELHFVEKAAAVSLENVLLDVKELGKGMDLIRKESHHHDN----------TFLRNFVSSNEGKLDKLQKDARTAEEAYAAVVLYFGE-NPKTTPPSVFFPVFARFIKSYKEAELENEMRKKQEEVLREKMLAQEAKKLDPKSPVQKNKRQQQDLIAELRRRQAKDHRPVYEGKDGTIEDIITVLKSVPFTART-AKRGSRFFCD---TSLFED 1029
BLAST of Formin-like protein vs. Ensembl Mouse
Match: Fmnl2 (formin-like 2 [Source:MGI Symbol;Acc:MGI:1918659]) HSP 1 Score: 227.639 bits (579), Expect = 1.593e-60 Identity = 173/507 (34.12%), Postives = 275/507 (54.24%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + + + TM T S + +I + S+ S+ R S R+S + NT + K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V++MQFINI+VHSVE++N RV+LQYEFT LGLD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + R+S ++++I +L Q G I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS--FAQYAVTFDFESVESTMESTVDKSKPW---SRSIEDLHRGSNLPSPVGNSVSR----SGRHS-----------ALRYNTLPSRRTLKNSRLV--SKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQ-RQSTLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 163.696 bits (413), Expect = 2.716e-40 Identity = 132/413 (31.96%), Postives = 211/413 (51.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE+IFK + P +D K Q+ S K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ LP+ E + R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ ++EK+ + F++EL YVE A+ VSL N++ +EL G+D E ++ + T L F+ N ++ L+ + A+ AF V++FGE + +T P +FF VRF+ ++K+A EN R+
Sbjct: 592 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKT-----KAQGPAIDLSSSKQKITQK----------------ASSKVTLLEANRAKNL----------------AITLRKAGKSADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLLQKMTIMAFIGNFTESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYQQVTLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHN---------TLLKEFLLHNEGKLKKLQEDAKIAQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKQAEEENELRK 957
BLAST of Formin-like protein vs. Ensembl Mouse
Match: Fmnl2 (formin-like 2 [Source:MGI Symbol;Acc:MGI:1918659]) HSP 1 Score: 227.639 bits (579), Expect = 2.597e-60 Identity = 173/507 (34.12%), Postives = 275/507 (54.24%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + + + TM T S + +I + S+ S+ R S R+S + NT + K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V++MQFINI+VHSVE++N RV+LQYEFT LGLD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + R+S ++++I +L Q G I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS--FAQYAVTFDFESVESTMESTVDKSKPW---SRSIEDLHRGSNLPSPVGNSVSR----SGRHS-----------ALRYNTLPSRRTLKNSRLV--SKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQ-RQSTLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 163.696 bits (413), Expect = 3.072e-40 Identity = 132/413 (31.96%), Postives = 211/413 (51.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE+IFK + P +D K Q+ S K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ LP+ E + R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ ++EK+ + F++EL YVE A+ VSL N++ +EL G+D E ++ + T L F+ N ++ L+ + A+ AF V++FGE + +T P +FF VRF+ ++K+A EN R+
Sbjct: 626 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKT-----KAQGPAIDLSSSKQKITQK----------------ASSKVTLLEANRAKNL----------------AITLRKAGKSADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLLQKMTIMAFIGNFTESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYQQVTLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHN---------TLLKEFLLHNEGKLKKLQEDAKIAQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKQAEEENELRK 991
BLAST of Formin-like protein vs. Ensembl Mouse
Match: Fmnl2 (formin-like 2 [Source:MGI Symbol;Acc:MGI:1918659]) HSP 1 Score: 227.254 bits (578), Expect = 2.969e-60 Identity = 173/507 (34.12%), Postives = 275/507 (54.24%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + + + TM T S + +I + S+ S+ R S R+S + NT + K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V++MQFINI+VHSVE++N RV+LQYEFT LGLD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + R+S ++++I +L Q G I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS--FAQYAVTFDFESVESTMESTVDKSKPW---SRSIEDLHRGSNLPSPVGNSVSR----SGRHS-----------ALRYNTLPSRRTLKNSRLV--SKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQ-RQSTLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 163.696 bits (413), Expect = 3.189e-40 Identity = 132/413 (31.96%), Postives = 211/413 (51.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE+IFK + P +D K Q+ S K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ LP+ E + R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ ++EK+ + F++EL YVE A+ VSL N++ +EL G+D E ++ + T L F+ N ++ L+ + A+ AF V++FGE + +T P +FF VRF+ ++K+A EN R+
Sbjct: 626 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKT-----KAQGPAIDLSSSKQKITQK----------------ASSKVTLLEANRAKNL----------------AITLRKAGKSADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLLQKMTIMAFIGNFTESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYQQVTLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHN---------TLLKEFLLHNEGKLKKLQEDAKIAQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKQAEEENELRK 991
BLAST of Formin-like protein vs. Ensembl Mouse
Match: Fmnl2 (formin-like 2 [Source:MGI Symbol;Acc:MGI:1918659]) HSP 1 Score: 227.254 bits (578), Expect = 3.215e-60 Identity = 173/507 (34.12%), Postives = 275/507 (54.24%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + + + TM T S + +I + S+ S+ R S R+S + NT + K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V++MQFINI+VHSVE++N RV+LQYEFT LGLD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + R+S ++++I +L Q G I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS--FAQYAVTFDFESVESTMESTVDKSKPW---SRSIEDLHRGSNLPSPVGNSVSR----SGRHS-----------ALRYNTLPSRRTLKNSRLV--SKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQ-RQSTLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 163.31 bits (412), Expect = 4.012e-40 Identity = 147/499 (29.46%), Postives = 238/499 (47.70%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXX-------XXXXXXXXXXXXPKGDQTRKKN------RTRQI--------NADGIMDEIMAGLDYQPLQAGLHARRGKRDNTD 3364
P+ W L+ Q GTVF EID +I + L++D FE+IFK P +D K Q+ S K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ LP+ E + R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ ++EK+ + F++EL YVE A+ VSL N++ +EL G+D E ++ + T L F+ N ++ L+ + A+ AF V++FGE + +T P +FF VRF+ ++K+A EN R+ ++ +++ P R++ R RQ+ DG +++I+ L QP + RR R D
Sbjct: 626 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKA-----QGPAIDLSSSKQKITQK----------------ASSKVTLLEANRAKNL----------------AITLRKAGKSADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLLQKMTIMAFIGNFTESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYQQVTLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHN---------TLLKEFLLHNEGKLKKLQEDAKIAQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDAKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFD 1077
BLAST of Formin-like protein vs. Ensembl Mouse
Match: Fmnl2 (formin-like 2 [Source:MGI Symbol;Acc:MGI:1918659]) HSP 1 Score: 226.868 bits (577), Expect = 3.553e-60 Identity = 173/507 (34.12%), Postives = 275/507 (54.24%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + + + TM T S + +I + S+ S+ R S R+S + NT + K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V++MQFINI+VHSVE++N RV+LQYEFT LGLD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + R+S ++++I +L Q G I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS--FAQYAVTFDFESVESTMESTVDKSKPW---SRSIEDLHRGSNLPSPVGNSVSR----SGRHS-----------ALRYNTLPSRRTLKNSRLV--SKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQ-RQSTLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 162.925 bits (411), Expect = 4.796e-40 Identity = 132/413 (31.96%), Postives = 211/413 (51.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE+IFK + P +D K Q+ S K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ LP+ E + R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ ++EK+ + F++EL YVE A+ VSL N++ +EL G+D E ++ + T L F+ N ++ L+ + A+ AF V++FGE + +T P +FF VRF+ ++K+A EN R+
Sbjct: 626 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKT-----KAQGPAIDLSSSKQKITQK----------------ASSKVTLLEANRAKNL----------------AITLRKAGKSADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLLQKMTIMAFIGNFTESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYQQVTLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHN---------TLLKEFLLHNEGKLKKLQEDAKIAQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKQAEEENELRK 991
BLAST of Formin-like protein vs. UniProt/SwissProt
Match: sp|Q96PY5|FMNL2_HUMAN (Formin-like protein 2 OS=Homo sapiens OX=9606 GN=FMNL2 PE=1 SV=3) HSP 1 Score: 227.639 bits (579), Expect = 1.648e-59 Identity = 170/509 (33.40%), Postives = 275/509 (54.03%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQ--RNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S ++ +++S +T+ + D S ++S+ + S R S + NT + K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V++MQFINI+VHSVE++N RV+LQYEFT LGLD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + R+S ++++I +L Q G I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-------------------FAQYAVTFDFESVESTVESS---VDKSKPWSRSIEDLHRGSNLPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLV--SKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQ-RQSTLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 165.236 bits (417), Expect = 6.011e-40 Identity = 149/495 (30.10%), Postives = 243/495 (49.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXX----XXXXXXXXPKGDQTRKKN---------RTRQI--------NADGIMDEIMAGLDYQPLQAGLHARRGKR 3352
P+ W L+ Q GTVF EID +I + L++D FE+IFK + P +D K ++ G+N K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ LP+ E + R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ ++EK+ + F++EL YVE A+ VSL N++ +EL G+D E ++ + T L F+ N ++ L++ + A+ AF V++FGE + +T P +FF VRF+ ++K+A EN R+ ++ +K + +PK + K R RQ+ DG +++I+ L P A A+RG R
Sbjct: 627 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKT-----KAQGPAIDLSSSK------------QKIPQKGSN----KVTLLEANRAKNL----------------AITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHN---------TLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITVLKTVPFTART-AKRGSR 1073
BLAST of Formin-like protein vs. UniProt/SwissProt
Match: sp|A2APV2|FMNL2_MOUSE (Formin-like protein 2 OS=Mus musculus OX=10090 GN=Fmnl2 PE=1 SV=2) HSP 1 Score: 227.639 bits (579), Expect = 1.816e-59 Identity = 173/507 (34.12%), Postives = 275/507 (54.24%), Query Frame = 2
Query: 83 PPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
P P LE+ R+ + + ++++ P + + Q + +K EL+ + F+ KNP + Y+ +KG +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + + + TM T S + +I + S+ S+ R S R+S + NT + K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM +R+ +D NID+ V++MQFINI+VHSVE++N RV+LQYEFT LGLD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS L E+L E E KI E E ++ + KEL+ + + + V +LR +++ + R+S ++++I +L Q G I ++KK
Sbjct: 26 PEPGELEE---RFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHT---YIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS--FAQYAVTFDFESVESTMESTVDKSKPW---SRSIEDLHRGSNLPSPVGNSVSR----SGRHS-----------ALRYNTLPSRRTLKNSRLV--SKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRN------EDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQ-RQSTLEKKIHELEKQ-----------GTIKIQKK 486 HSP 2 Score: 163.696 bits (413), Expect = 2.149e-39 Identity = 132/413 (31.96%), Postives = 211/413 (51.09%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE+IFK + P +D K Q+ S K++LL+ NR K + +I+ R+ G+ + AI FD+ + D L+ LP+ E + R E L L++EDR + S I+R+ K+ + ++ F E+ L ++ + A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YI+ ++EK+ + F++EL YVE A+ VSL N++ +EL G+D E ++ + T L F+ N ++ L+ + A+ AF V++FGE + +T P +FF VRF+ ++K+A EN R+
Sbjct: 626 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKT-----KAQGPAIDLSSSKQKITQK----------------ASSKVTLLEANRAKNL----------------AITLRKAGKSADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLLQKMTIMAFIGNFTESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYQQVTLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHN---------TLLKEFLLHNEGKLKKLQEDAKIAQDAFDDVVKYFGE-NPKTTPPSVFFPVFVRFVKAYKQAEEENELRK 991
BLAST of Formin-like protein vs. UniProt/SwissProt
Match: sp|Q6NXC0|FMNL3_DANRE (Formin-like protein 3 OS=Danio rerio OX=7955 GN=fmnl3 PE=2 SV=2) HSP 1 Score: 226.483 bits (576), Expect = 3.064e-59 Identity = 171/532 (32.14%), Postives = 283/532 (53.20%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIES--DFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKP 1591
MGN + +K+ + P P E E+R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++G K+T K + Q + ++L EISLRTNH+ WV +FL ++ GL+ILV+Y+S + + G+E+ DFS +S R + +N +R S + ++S SK K+ V S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E+ RF+ LM ++R +D NID+ V+ MQFINI+VHSVE++N RV+LQYEFT LGLD FL+K + D+L+ Q+ AYLDN+ D LLEDAE K + + E LE+ +S + E+L E E K+ + E ++ +KEL + + S V +LR I++ + R +++++++ +L Q G I ++K+P
Sbjct: 1 MGNIESVDGQSEMKHHIMPLKVPMPDPTE-LEERFAIVLNSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLRGYLDPKVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENRGLDILVEYLS----------------------------FAQCAVMLDFEGLENGEDFSLDKAKSWSRSIEDLHQNGCNTLVRSARQSVLRYGSTSNSKTIKNSRLV--SQKDDVHVCIMCLRAIMNYQYGFNLVMSHAHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCKEKHRFEKLMEYFRS------EDGNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLDDFLEKSKHTESDKLSVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHLSHVTEKLLDVENETMTKVADLEKQLLHKDKELAVIKETYESASTQVHTLRRMIQEKDAAFQ-RHNNIEKQLLELE-----------QQGTIRLRKQP 480 HSP 2 Score: 201.445 bits (511), Expect = 3.077e-51 Identity = 155/493 (31.44%), Postives = 250/493 (50.71%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXXXXXXXXXX--PKGDQTRKKNRTRQINA-----------------DGIMDEIMAGLDYQPLQAGLHARRGKR 3352
P+ W L+ Q GTVF EID ++ ++LDL+ FE++FK P +D K Q+ N K+ LLD NR K + +I+ R+ + + AI FD+ + D L+ LP+ E+ + R E L+ LA EDR + L S I+R+ ++ I ++ F++ L ++ + A SV S KLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA ++EK+P+L NF++EL +V+ A+ VSL N++ +EL G+D V E SL +AV L F + + T+++ L + A+ AF V +FGE +T P +FF VRF+ ++K+A+ EN +R+ +E R+K ++ + PK +K+++ +++ A DG +++I+ L P A A+RG R
Sbjct: 591 PVFNWTALKPNQINGTVFNEIDDDRVLEELDLEKFEELFKTKA-----QGPVVDLSCSKSKVSQKVIN----------------KVQLLDANRSKNL----------------AITLRKANKTTEEICKAIQTFDLKALPVDFVECLMRFLPTEAESKLLRQYERERRPLDQLAEEDRFMLLFSKIERLTQRMSIITFVGNFNDNVNMLTPQLNAIIAASASVKSSPKLKKILEIILALGNYMNSSKRGSVYGFKLQSLDLLLDTKSTDRKMTLLHYIALVVKEKYPELANFYNELHFVDKAAAVSLENVLLDVKELGKGMDLVRRECSLHDHAV----------LKGFAQTSDTQLDKLAKDAKTAEEAFNNVVLYFGESP-KTTPPSVFFPVFVRFIRAYKEAVEENEQRKKQEEAMREKLLAQEAKQHDPKVQAQKKRHQQQELIAELRRRQAKDHRPVYEGKDGTIEDIITVLKSVPFTART-AKRGSR 1034
BLAST of Formin-like protein vs. UniProt/SwissProt
Match: sp|Q8IVF7|FMNL3_HUMAN (Formin-like protein 3 OS=Homo sapiens OX=9606 GN=FMNL3 PE=1 SV=3) HSP 1 Score: 217.238 bits (552), Expect = 2.723e-56 Identity = 161/492 (32.72%), Postives = 258/492 (52.44%), Query Frame = 2
Query: 17 MGNQQQGSPYP----RLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRD 1465
MGN + P + + P P+ E E+R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++ +T K + Q + ++L EISLRTNH+ WV +FL ++ GL++LVDY+S + M F +G + +S +I + S S SL R S R S + + + S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E RF+ LM ++R+ +D NID+ V+ MQFINI+VHSVE++N RV+LQYEFT LGL+ FL+K + ++L Q+ AYLDN+ D LLEDAE K + + E LE+ +S L E+L E E ++ E E ++ + EKELE + + S V +LR I++
Sbjct: 1 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCE-LEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLS-----FAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSLAR----SARQSVLRYSTLPGRRALKNSRLV-------------SQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN------EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKE 460 HSP 2 Score: 202.601 bits (514), Expect = 1.039e-51 Identity = 137/413 (33.17%), Postives = 214/413 (51.82%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF E+D +I + LDLD FE++FK + P LD I K A + K++LL+ NR K + +I+ R+ GR + AI FD+ + D L+ LP+ E + R E L LA EDR + L S ++R+ ++ + ++ F + L ++ + A SV SQKLK++LEI+LA GN MN S+RG GF++QSLD+L + +S D K +L+++IA ++EK+PDL NF+ EL +VE A+ VSL N++ +EL G++ + E S+ N+V L NF+ N +++ L+ + A+ A+ V +FGE +T P +FF VRF+ S+K+A EN R+
Sbjct: 572 PVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKT-----KAQGPALDLICSKN----------------KTAQKAASKVTLLEANRAKNL----------------AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSV----------LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESP-KTTPPSVFFPVFVRFIRSYKEAEQENEARK 936
BLAST of Formin-like protein vs. UniProt/SwissProt
Match: sp|Q6ZPF4|FMNL3_MOUSE (Formin-like protein 3 OS=Mus musculus OX=10090 GN=Fmnl3 PE=1 SV=2) HSP 1 Score: 214.542 bits (545), Expect = 1.571e-55 Identity = 156/469 (33.26%), Postives = 252/469 (53.73%), Query Frame = 2
Query: 74 NEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRD 1465
+ P P+ E E+R+ + + S+++ P + + Q + +K +L+ + F+ KNP + Y+ ++ +T K + Q + ++L EISLRTNH+ WV +FL ++ GL++LVDY+S + M F +G + +S +I + + S SL R S R S + + + S K+ +H+C+ C R I+N Q G + + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + +E RF+ LM ++R+ +D NID+ V+ MQFINI+VHSVE++N RV+LQYEFT LGL+ FL+K + ++L Q+ AYLDN+ D LLEDAE K + + E LE+ +S L E+L E E ++ E E ++ + EKELE + + S V +LR I++
Sbjct: 24 GKTPMPEPCE-LEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQERFQVKNPPHT---YIQKLQSFLDPNVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLS-----FAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPNALSAPFTNSLAR----SARQSVLRYSTLPGRRALKNSRLV-------------SQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN------EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSNQVHTLRRLIKE 460 HSP 2 Score: 200.29 bits (508), Expect = 5.413e-51 Identity = 136/413 (32.93%), Postives = 214/413 (51.82%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF E+D +I + LDLD FE++FK + P LD I K A + K++LL+ NR K + +I+ R+ GR + AI FD+ + D L+ LP+ E + R E L LA EDR + L S ++R+ ++ + ++ F + L ++ + A SV SQKLK++LEI+LA GN MN S+RG GF++QSLD+L + +S D K +L+++IA ++EK+P+L NF+ EL +VE A+ VSL N++ +EL G++ + E S+ N+V L NF+ N +++ L+ + A+ A+ V +FGE +T P +FF VRF+ S+K+A EN R+
Sbjct: 572 PVFNWTALKPNQINGTVFSELDDEKILEDLDLDRFEELFKT-----KAQGPALDLICSKN----------------KTAQKAASKVTLLEANRAKNL----------------AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPELANFWQELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSV----------LRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESP-KTTPPSVFFPVFVRFIRSYKEAEQENEARK 936
BLAST of Formin-like protein vs. TrEMBL
Match: A0A1I8Q476 (Uncharacterized protein OS=Stomoxys calcitrans OX=35570 GN=106094087 PE=4 SV=1) HSP 1 Score: 367.081 bits (941), Expect = 7.079e-104 Identity = 336/1177 (28.55%), Postives = 552/1177 (46.90%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEF---QNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMS---QILLH-------LIKSEEMQIFPITMNGTNTISSNYQST-GATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLS---------DRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVDMNDSQPALNNDTVETHKGASNIPHSAVSTNKPKLPHTPLKSKEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMDVSI---TSVAGDAPLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPL---ACAITNFDMAS---EAADRLLYQLPSFQETDMYRD--ITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARR----QMGDXXXXXXXXXXXXXXPKGDQTR-----------KKNRTRQINA-------DGIMDEIMAGLDYQPLQAGLHARRGKRDNTDS 3367
MGN P R S + P P + E+ ++++ + S+D+ P + + + +K +++ + E K HY+T ++ K + S RK + + Q+L EISLRTNH+EWV +FL + GL+ LVDY+S Q++ H L +S+E F + +G +S N ST G S N +ES N S F+A + R S + R S ++ D +H+C+ C R I+NN+ G M ++++ IN I + L+H S +TK+L+L+LL+A+CL++GGHE +L AFD FK + +E RF TLM ++ + E +NID+ V+ MQF+NI+VHSVE++N RV+LQYEFT LGLD +L+KL+ + L Q+ AYLDN+ D + L+ED+E K A + +RV++ E ++E+ R EL + + +++R + + D E R I ++Q K + +Q+ N+ ++ R +SN N +KE V+ +H+ A+ +P P P PL S A T P+ Q A + I + P+P ++I P + W L+ Q GT+F E+D +I K +D + FE+ FK+ + +DG +R + D ISLL+ R L++ +IS R+ P+ AI + D+ E + L +P+ E Y++ I + N+L ED+ + LS ++R+ KL + YM F + + +I+++ A S+ +S+K K +LEIVLAFGN +N ++RG A GF++QSLD L + +S D + SL++YI I +KFP+L NF SEL + A++VSL N++ +L G++ V +E L + + L +F+ + ++ ++ + + A+ AF + VE+FGE + A FF +VRF +FK EN +R Q KK E+ K +Q + K N R+ +G +++I+ GL +P + RR +R D+
Sbjct: 50 MGNSSNYHPV-RQPSVRSRSLHPMPTS-EELDRKFTKVLASMDLPPDKAKLLKNYDDEKKWDIICDQEMVQAKDPPSHYLTKLRTYLDPKASRSHRKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNRGLDALVDYLSFRLQMMRHEQRVQESLSESDERLNFNNSGDGVGAVSLNGTSTLGGVSSSNLLESSRYQHGNSS---TFNAISNSILRPSLLDVLDTPSVRRRSRHIAKLNMGASTDD-----IHVCIMCLRAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILSAFDNFKNICQETHRFQTLMEYFMNFEA-----FNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLEKLRLTESEELKVQISAYLDNVFDVAALMEDSETKTAAL--------------------------------ERVQELEDQIEREIDRNSELLYKLAEVDTEVRFLKADREDLLATKLKFDEEVTTLRRILKQNEQELKKRESLLQSKNLELQTLTRSLPRSTSNIANELDINTCAKESPVECVSPPLPPPPPPPHSHEQATCLPPPPPPPAPPAPPPPPLGSGLTPNAFTPPVPPPSQRALPHQNSTSMIFQPPPPPVAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIYKYIDFNEFEERFKIGVGGGLSSGSNSE-VDGTLQSYPSKR------------FKKPDNISLLEHTR----------------LRNIAISRRKLDMPIDEVISAIHSLDLKKLSLENVELLQKMVPTDVEVKSYKEYIIERKDQNLLTEEDKFMLQLSKVERISSKLSIMNYMGNFFDCLHLICPQIQSITSASTSLKQSRKFKALLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRQKFPELLNFESELYCTDKAAQVSLENIVTDVHDLEKGMELVKKEAELRVKGSQTHI------LRDFLNNSEDKLKKIKMELKMAQDAFKECVEYFGESS-RNADAAAFFSLIVRFSRAFKAYDQENEQRRRLEQAAAAAASKKESEQVQLRNKSNQKKQQDAVINELKCKANSVREKKLLQQDEVYNGALEDILLGLKSEPYRRADAVRRSQRRRIDN 1143
BLAST of Formin-like protein vs. TrEMBL
Match: A0A4S2LX82 (GBD/FH3 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_004237 PE=4 SV=1) HSP 1 Score: 350.517 bits (898), Expect = 8.271e-104 Identity = 216/499 (43.29%), Postives = 309/499 (61.92%), Query Frame = 2
Query: 101 EDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSK--RKDEFQNAKQILSATEISLRTNHVEWVYDFLKHSGLEILVDYMSQILLHLIKSE--------EMQIFPI-TMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLM-YFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVE-------SLRSKIRDINVNLSDRESDMKREITDLHDQLKK 1540
E F+K W FIQSLDV P+ + I+QL A QK LL ++ KNPKCSAFHYV+LIKGLR + T SK R+ E Q+AK++L ATEISLRTN+V WVY+FL +GL++LV Y+S+++ LI+S E I PI + + T T+S + S+ P+AN SLR ++ + + + + NR T + DSI++ LH +KCFR +LNNQ+GC M F++ INVIT+CL+HPS QTKSL+L+LL+AVCLI GGHERV+KAFD FK E +RF++L+ YF+ H + P D+YN+D+ VS +QF NI+VHS ++I LRVYLQ EF LGL FL++L R DRL RQ++AY DN VD ++LLED++A+E + E E+ E ++ LQ +L E E + + + L+ QSR EL E +L+S+++D + + +DRE ++ I +L + + +
Sbjct: 7 EIFQKNWASFIQSLDVGPEKAKGIEQLPADQKRHLLESYVTKNPKCSAFHYVSLIKGLRVGRSTLSKNSRRSEGQHAKEVLMATEISLRTNNVGWVYEFLDQNGLDVLVTYVSKVIRMLIRSNIGSDSSDMESPIIPIESFDSTETVSRSLPSS-------------RPKAN-SLRSLWCIRRPANGDEFGRRRSLNRPNRFTLQ----------LSDSIRDSLHQAVKCFRALLNNQRGCSMVFDHPRAINVITLCLLHPSSQTKSLVLELLAAVCLIIGGHERVIKAFDNFKREVGEFQRFESLVHYFFTHETSSPADEYNVDFMVSCIQFFNIVVHSTDDIMLRVYLQEEFRHLGLVLFLQRLHNRASDRLVRQIEAYNDNEVDVAMLLEDSQARELYQQELEQRETEMFALQTRLG-------SIQTEHEAKTAELQATLDALQSRCAELEGQHEAQIGQLNTLQSRLKDQDRSATDREKVLEARIQELEETISR 474
BLAST of Formin-like protein vs. TrEMBL
Match: A0A1I8Q468 (Uncharacterized protein OS=Stomoxys calcitrans OX=35570 GN=106094087 PE=4 SV=1) HSP 1 Score: 366.696 bits (940), Expect = 1.182e-103 Identity = 318/1089 (29.20%), Postives = 522/1089 (47.93%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEF---QNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMS---QILLH-------LIKSEEMQIFPITMNGTNTISSNYQST-GATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLS---------DRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVDMNDSQPALNNDTVETHKGASNIPHSAVSTNKPKLPHTPLKSKEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMDVSI---TSVAGDAPLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPL---ACAITNFDMAS---EAADRLLYQLPSFQETDMYRD--ITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
MGN P R S + P P + E+ ++++ + S+D+ P + + + +K +++ + E K HY+T ++ K + S RK + + Q+L EISLRTNH+EWV +FL + GL+ LVDY+S Q++ H L +S+E F + +G +S N ST G S N +ES N S F+A + R S + R S ++ D +H+C+ C R I+NN+ G M ++++ IN I + L+H S +TK+L+L+LL+A+CL++GGHE +L AFD FK + +E RF TLM ++ + E +NID+ V+ MQF+NI+VHSVE++N RV+LQYEFT LGLD +L+KL+ + L Q+ AYLDN+ D + L+ED+E K A + +RV++ E ++E+ R EL + + +++R + + D E R I ++Q K + +Q+ N+ ++ R +SN N +KE V+ +H+ A+ +P P P PL S A T P+ Q A + I + P+P ++I P + W L+ Q GT+F E+D +I K +D + FE+ FK+ + +DG +R + D ISLL+ R L++ +IS R+ P+ AI + D+ E + L +P+ E Y++ I + N+L ED+ + LS ++R+ KL + YM F + + +I+++ A S+ +S+K K +LEIVLAFGN +N ++RG A GF++QSLD L + +S D + SL++YI I +KFP+L NF SEL + A++VSL N++ +L G++ V +E L + + L +F+ + ++ ++ + + A+ AF + VE+FGE + A FF +VRF +FK EN +R+
Sbjct: 50 MGNSSNYHPV-RQPSVRSRSLHPMPTS-EELDRKFTKVLASMDLPPDKAKLLKNYDDEKKWDIICDQEMVQAKDPPSHYLTKLRTYLDPKASRSHRKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNRGLDALVDYLSFRLQMMRHEQRVQESLSESDERLNFNNSGDGVGAVSLNGTSTLGGVSSSNLLESSRYQHGNSS---TFNAISNSILRPSLLDVLDTPSVRRRSRHIAKLNMGASTDD-----IHVCIMCLRAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILSAFDNFKNICQETHRFQTLMEYFMNFEA-----FNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLEKLRLTESEELKVQISAYLDNVFDVAALMEDSETKTAAL--------------------------------ERVQELEDQIEREIDRNSELLYKLAEVDTEVRFLKADREDLLATKLKFDEEVTTLRRILKQNEQELKKRESLLQSKNLELQTLTRSLPRSTSNIANELDINTCAKESPVECVSPPLPPPPPPPHSHEQATCLPPPPPPPAPPAPPPPPLGSGLTPNAFTPPVPPPSQRALPHQNSTSMIFQPPPPPVAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIYKYIDFNEFEERFKIGVGGGLSSGSNSE-VDGTLQSYPSKR------------FKKPDNISLLEHTR----------------LRNIAISRRKLDMPIDEVISAIHSLDLKKLSLENVELLQKMVPTDVEVKSYKEYIIERKDQNLLTEEDKFMLQLSKVERISSKLSIMNYMGNFFDCLHLICPQIQSITSASTSLKQSRKFKALLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRQKFPELLNFESELYCTDKAAQVSLENIVTDVHDLEKGMELVKKEAELRVKGSQTHI------LRDFLNNSEDKLKKIKMELKMAQDAFKECVEYFGESS-RNADAAAFFSLIVRFSRAFKAYDQENEQRR 1055
BLAST of Formin-like protein vs. TrEMBL
Match: H2MQ17 (Formin-like 2a OS=Oryzias latipes OX=8090 GN=fmnl2 PE=4 SV=2) HSP 1 Score: 362.073 bits (928), Expect = 1.389e-102 Identity = 326/1100 (29.64%), Postives = 531/1100 (48.27%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNG---TNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVD--MNDSQPALNNDTVETHKGASNIPHSAVSTNK----PKLPHTPLKS---KEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMD-------VSITSVAGDAPL--------IKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGESLNV--LANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
MGN K + P P++ E E+R+ + + S+++ P + + Q + +K EL+ + F+ KNP T ++ LRSY + K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y++ + + +G NT + +S + S + S ++RR + S + + + I RN++ + +S C +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E +RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS + E+L E E KI E E ++ + K+LE + + S ++SLR +++ + + R+S+++++I +L Q G I + KK D+ + + E L + PA+N+D G + P LP+ PL S P A+D P+ M+ + + SV P+ W L+ Q GTVF EID +I + L++D FE++FK + PP+D K IQ+ K++LLD NR K + +I+ R+ G+ + AI FD+ + D L+ P+ E ++R E V L NEDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA ++EK+ + F++EL YVE A+ VSL N + +EL G+D E S+ + T L +F+ N +++ L++ + A+ AF + +++FGE +T P +FF VRF+ ++++A +N +R+
Sbjct: 1 MGNAGSMDQTTYFKGHGVPTKLPMPESGE-LEERFAIVLNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYLQKLRSYLDPAVPRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLA-----------FAQYAVNYDGDSVENTEDALDKSKTWSRSIEDLHRGGSFHHGGTMRR------GGTLPPSTTGNGITRIGRNSTLRYSTMSIRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCVETQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDDYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHMTEKLQDTENEAMSKIVELEKQLMQRNKDLEAIREAYKDTSSQIQSLRQMLKEKDEAIQ-RQSNLEKKIHELEKQ-----------GTIKIHKK-------GDGDISILASSPAGVEGLTGSTATGNGPAVNSDHSGAGGGMAGPPPPPPPPPPLPVNGTLPNGPLPSVSVPAQPPPPPPPPPPPPGLASDLFPSAPPPPPMPPPLPGCGTPTVIMNSGLAEGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----KAQGPPIDFNVSKQKVIQK----------------GPSKVTLLDSNRAKNL----------------AITLRKVGKTTEEICKAIQLFDLRTLPVDFVECLMRFQPTENEVKVFRQFEKERKPVESLTNEDRFMMQFSKIERLMQKMTIMAFIGNFSESVLMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVKEKYSQVSLFYNELNYVEKAAGVSLDNALLDVKELQRGMDLTKREYSMHGHN---------TMLKDFITHNESKLKKLQDDAKIAQDAFDEVLKFFGENS-KTTPPSVFFPVFVRFVKAYRQAEEDNEQRK 1004
BLAST of Formin-like protein vs. TrEMBL
Match: I0AYW0 (Dishevelled-associated activator of morphogenesis 1 OS=Schmidtea mediterranea OX=79327 GN=DAAM1 PE=2 SV=1) HSP 1 Score: 357.836 bits (917), Expect = 1.149e-101 Identity = 206/433 (47.58%), Postives = 284/433 (65.59%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPP--PQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGL---RSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDI 1300
MG+ S P+ K+ NS P NL+ FEK FIQSLDV P+N++ IDQL+ QK +LLLNFE+KNPK SAFHYVTLIK L +S + + +K+ D+ + +LSATE+SLRTN+V+WVYDFL ++GLE+L+DYMS+ L+ + + NY++ + N ++SD + S +F + + N I R +S V+K S +V +S+K LH LKC RTILNNQ+GC+MAF + I+VI +CL+HP+YQTK+L+L+ L+A+CLI G ++VL AF+ FK +T E +RFDTL+ ++R HET +DDYNID+ VS QFINI+VHS E+INLRVYLQ EFT+LGLD F +KL+ER GDRL +QV AY N VD ++LLED+E KE + + E+LE +
Sbjct: 1 MGSTSSKST-PQYKFINSGEGRLEMRPTNLQ-FEKXXDTFIQSLDVGPENVRQIDQLDPDQKEQLLLNFESKNPKYSAFHYVTLIKALQTGKSIRKSFNKKPDD--DPVHVLSATEVSLRTNNVDWVYDFLNNNGLEVLLDYMSKTLVLFL------------------NINYKNIETKKTLN-LQSDTKTHLSSS--DLFKSKKFNCCA---------SIKRRSSVVTKFQNSKDSVNESVKNSLHQGLKCMRTILNNQRGCEMAFVHSRAIDVIALCLLHPNYQTKTLVLETLAAICLIVNGLQKVLAAFEYFKEITGESRRFDTLITYFRDHETFKVDDYNIDFMVSCTQFINIVVHSGEDINLRVYLQQEFTILGLDDFYRKLEERSGDRLKKQVAAYNGNRVDVAILLEDSETKETVLLDYEKLEHEF 399 HSP 2 Score: 266.544 bits (680), Expect = 5.494e-70 Identity = 167/486 (34.36%), Postives = 254/486 (52.26%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGES---LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXXXXXXXXXXPKGD--------------QTRKK-----NRTRQINADGIMDEIMAGLDYQPLQAGLHARRG 3346
P+ W++L+NQQ GTVF ++ + +L+ + FE IFK+ P+ D+I ++ N S + + +K +LLD ++ +C+ +++ +L QEKL H I L +I ++ E DR+LYQLP+ + YR +N L +EDRL+ L ++R++ KLE ++Y+ F E Y +L EK+ V A +V SQKLK+ILEI+LA+GN MN SRRG GFR+QSLD+L + +S D W+LM + +E KF +L +F E+ +VE AS++ + + L G+ +V +E++ N P RL F +N L AK F++ EWFGE+ +PD+FFG RF ++FKK++ + +R+ E D + RKK NRTRQINADGIMD+I+AGLD PLQA +H +R
Sbjct: 552 PVFNWSVLKNQQLKGTVFVSMNDEVLYDKLEFEKFENIFKLNPVG--------DSIPN---------GVDSNDSSEKTSKRKPEKKTLLDGSKHRCLGVLLKFLDQEKL--HSDI--------LCKSINQLXVSVEVXDRILYQLPTNDDXKTYRRYEYSDKLPINALTDEDRLLLTLCKVERLQQKLEVVVYIHNFPEAYKSLVEKVTFVTRASLAVRSSQKLKQILEIILAYGNLMNSSRRGIMYGFRLQSLDLLTDTKSLDKSWTLMQFFVDIVESKFQNLSDFSDEMRFVEQASKIPMEAITTDVASLVGGMKQVRDEMNCNTNQ--------PPRLKKFFEDNENLTADLSKSAANAKETFLQAAEWFGERQ-NNPTPDVFFGIFHRFTENFKKSLEDVRKRRAQSIILNIVPTEETPKAKXKDKNLSMEELQKKLALEARKKNRRMNNRTRQINADGIMDDILAGLDKTPLQAEIHPKRS 1001
BLAST of Formin-like protein vs. Ensembl Cavefish
Match: fmnl2a (formin-like 2a [Source:ZFIN;Acc:ZDB-GENE-081105-70]) HSP 1 Score: 211.075 bits (536), Expect = 2.721e-55 Identity = 160/495 (32.32%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 140 LDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
+++ P + + Q + +K EL+ + F+ KNP T I+ L+SY +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + +T +G + ENG ++ + S R I D ++ + + R+++ S + +S C +H+C+ C R ++N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + EE+RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE+++S L E+L E E KI E E ++ KEL+ + +++ V +L+ +++ + + R+ +++++I +L Q G I ++KK
Sbjct: 1 MNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYIQKLKSYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-----------FAQYAVTFDGDSI-------------ENGADNAMDKSKSWS-RSIEDLHGGSNLPSPIVGNNINRAGRHSTLRCNTLPSRRTLKNSRLVCKKDDVHVCIMCLRAVMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCSEEQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLTEKLQDTENEAMSKIVELEKQLMHKNKELDAVREVYKDVNTQVHTLKRMVKEKDEAIQ-RQCNLEKKIHELEKQ-----------GTIKIQKK 446 HSP 2 Score: 171.4 bits (433), Expect = 7.726e-43 Identity = 135/413 (32.69%), Postives = 212/413 (51.33%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE++FK P +D K IQ+ N KI+LLD NR K + +I+ R+ G+ + AI FD+ + D L+ +P+ E R E L L +EDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA + EK+ + F++EL YVE A+ VSL N++ +EL G+D E S+ + T L +F++ N +++ L++ + A+ AF + V++FGE +T P +FF VRF+ ++++A EN R+
Sbjct: 585 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----RAQGPAIDVTSSKQKTIQKGPN----------------KITLLDSNRAKNL----------------AITLRKVGKTPEEICKAIQMFDLRTLPVDFVECLMRFIPTEPEVKALRQYEKERKPLENLTDEDRFMMQFSKIERLMQKMTIMAFVGNFCESVQMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVREKYQQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYSMHGHN---------TLLKDFIQHNESKLKKLQDDAKIAQDAFDEAVKFFGE-SAKTTPPSVFFPVFVRFVKAYRQAEEENEARK 950
BLAST of Formin-like protein vs. Ensembl Cavefish
Match: fmnl2a (formin-like 2a [Source:ZFIN;Acc:ZDB-GENE-081105-70]) HSP 1 Score: 211.075 bits (536), Expect = 2.798e-55 Identity = 160/495 (32.32%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 140 LDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
+++ P + + Q + +K EL+ + F+ KNP T I+ L+SY +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + +T +G + ENG ++ + S R I D ++ + + R+++ S + +S C +H+C+ C R ++N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + EE+RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE+++S L E+L E E KI E E ++ KEL+ + +++ V +L+ +++ + + R+ +++++I +L Q G I ++KK
Sbjct: 1 MNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYIQKLKSYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-----------FAQYAVTFDGDSI-------------ENGADNAMDKSKSWS-RSIEDLHGGSNLPSPIVGNNINRAGRHSTLRCNTLPSRRTLKNSRLVCKKDDVHVCIMCLRAVMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCSEEQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLTEKLQDTENEAMSKIVELEKQLMHKNKELDAVREVYKDVNTQVHTLKRMVKEKDEAIQ-RQCNLEKKIHELEKQ-----------GTIKIQKK 446 HSP 2 Score: 171.785 bits (434), Expect = 7.668e-43 Identity = 135/413 (32.69%), Postives = 212/413 (51.33%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE++FK P +D K IQ+ N KI+LLD NR K + +I+ R+ G+ + AI FD+ + D L+ +P+ E R E L L +EDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA + EK+ + F++EL YVE A+ VSL N++ +EL G+D E S+ + T L +F++ N +++ L++ + A+ AF + V++FGE +T P +FF VRF+ ++++A EN R+
Sbjct: 592 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----RAQGPAIDVTSSKQKTIQKGPN----------------KITLLDSNRAKNL----------------AITLRKVGKTPEEICKAIQMFDLRTLPVDFVECLMRFIPTEPEVKALRQYEKERKPLENLTDEDRFMMQFSKIERLMQKMTIMAFVGNFCESVQMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVREKYQQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYSMHGHN---------TLLKDFIQHNESKLKKLQDDAKIAQDAFDEAVKFFGE-SAKTTPPSVFFPVFVRFVKAYRQAEEENEARK 957
BLAST of Formin-like protein vs. Ensembl Cavefish
Match: fmnl2a (formin-like 2a [Source:ZFIN;Acc:ZDB-GENE-081105-70]) HSP 1 Score: 211.075 bits (536), Expect = 2.883e-55 Identity = 160/495 (32.32%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 140 LDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
+++ P + + Q + +K EL+ + F+ KNP T I+ L+SY +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + +T +G + ENG ++ + S R I D ++ + + R+++ S + +S C +H+C+ C R ++N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + EE+RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE+++S L E+L E E KI E E ++ KEL+ + +++ V +L+ +++ + + R+ +++++I +L Q G I ++KK
Sbjct: 1 MNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYIQKLKSYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-----------FAQYAVTFDGDSI-------------ENGADNAMDKSKSWS-RSIEDLHGGSNLPSPIVGNNINRAGRHSTLRCNTLPSRRTLKNSRLVCKKDDVHVCIMCLRAVMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCSEEQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLTEKLQDTENEAMSKIVELEKQLMHKNKELDAVREVYKDVNTQVHTLKRMVKEKDEAIQ-RQCNLEKKIHELEKQ-----------GTIKIQKK 446 HSP 2 Score: 171.785 bits (434), Expect = 5.775e-43 Identity = 135/413 (32.69%), Postives = 212/413 (51.33%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE++FK P +D K IQ+ N KI+LLD NR K + +I+ R+ G+ + AI FD+ + D L+ +P+ E R E L L +EDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA + EK+ + F++EL YVE A+ VSL N++ +EL G+D E S+ + T L +F++ N +++ L++ + A+ AF + V++FGE +T P +FF VRF+ ++++A EN R+
Sbjct: 592 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----RAQGPAIDVTSSKQKTIQKGPN----------------KITLLDSNRAKNL----------------AITLRKVGKTPEEICKAIQMFDLRTLPVDFVECLMRFIPTEPEVKALRQYEKERKPLENLTDEDRFMMQFSKIERLMQKMTIMAFVGNFCESVQMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVREKYQQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYSMHGHN---------TLLKDFIQHNESKLKKLQDDAKIAQDAFDEAVKFFGE-SAKTTPPSVFFPVFVRFVKAYRQAEEENEARK 957
BLAST of Formin-like protein vs. Ensembl Cavefish
Match: fmnl2a (formin-like 2a [Source:ZFIN;Acc:ZDB-GENE-081105-70]) HSP 1 Score: 211.075 bits (536), Expect = 3.195e-55 Identity = 160/495 (32.32%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 140 LDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
+++ P + + Q + +K EL+ + F+ KNP T I+ L+SY +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + +T +G + ENG ++ + S R I D ++ + + R+++ S + +S C +H+C+ C R ++N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + EE+RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE+++S L E+L E E KI E E ++ KEL+ + +++ V +L+ +++ + + R+ +++++I +L Q G I ++KK
Sbjct: 1 MNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYIQKLKSYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-----------FAQYAVTFDGDSI-------------ENGADNAMDKSKSWS-RSIEDLHGGSNLPSPIVGNNINRAGRHSTLRCNTLPSRRTLKNSRLVCKKDDVHVCIMCLRAVMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCSEEQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLTEKLQDTENEAMSKIVELEKQLMHKNKELDAVREVYKDVNTQVHTLKRMVKEKDEAIQ-RQCNLEKKIHELEKQ-----------GTIKIQKK 446 HSP 2 Score: 171.4 bits (433), Expect = 8.219e-43 Identity = 136/413 (32.93%), Postives = 213/413 (51.57%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE++FK P +D K IQ+ G N KI+LLD NR K + +I+ R+ G+ + AI FD+ + D L+ +P+ E R E L L +EDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA + EK+ + F++EL YVE A+ VSL N++ +EL G+D E S+ + T L +F++ N +++ L++ + A+ AF + V++FGE +T P +FF VRF+ ++++A EN R+
Sbjct: 592 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----RAQGPAIDVTSSKQKTIQK------------GPN----KITLLDSNRAKNL----------------AITLRKVGKTPEEICKAIQMFDLRTLPVDFVECLMRFIPTEPEVKALRQYEKERKPLENLTDEDRFMMQFSKIERLMQKMTIMAFVGNFCESVQMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVREKYQQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYSMHGHN---------TLLKDFIQHNESKLKKLQDDAKIAQDAFDEAVKFFGE-SAKTTPPSVFFPVFVRFVKAYRQAEEENEARK 957
BLAST of Formin-like protein vs. Ensembl Cavefish
Match: fmnl2a (formin-like 2a [Source:ZFIN;Acc:ZDB-GENE-081105-70]) HSP 1 Score: 210.69 bits (535), Expect = 4.441e-55 Identity = 160/495 (32.32%), Postives = 265/495 (53.54%), Query Frame = 2
Query: 140 LDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKK 1588
+++ P + + Q + +K EL+ + F+ KNP T I+ L+SY +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y+S + +T +G + ENG ++ + S R I D ++ + + R+++ S + +S C +H+C+ C R ++N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + EE+RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE+++S L E+L E E KI E E ++ KEL+ + +++ V +L+ +++ + + R+ +++++I +L Q G I ++KK
Sbjct: 1 MNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYIQKLKSYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLS-----------FAQYAVTFDGDSI-------------ENGADNAMDKSKSWS-RSIEDLHGGSNLPSPIVGNNINRAGRHSTLRCNTLPSRRTLKNSRLVCKKDDVHVCIMCLRAVMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCSEEQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLTEKLQDTENEAMSKIVELEKQLMHKNKELDAVREVYKDVNTQVHTLKRMVKEKDEAIQ-RQCNLEKKIHELEKQ-----------GTIKIQKK 446 HSP 2 Score: 172.17 bits (435), Expect = 5.712e-43 Identity = 135/413 (32.69%), Postives = 212/413 (51.33%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
P+ W L+ Q GTVF EID +I + L++D FE++FK P +D K IQ+ N KI+LLD NR K + +I+ R+ G+ + AI FD+ + D L+ +P+ E R E L L +EDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA + EK+ + F++EL YVE A+ VSL N++ +EL G+D E S+ + T L +F++ N +++ L++ + A+ AF + V++FGE +T P +FF VRF+ ++++A EN R+
Sbjct: 592 PVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----RAQGPAIDVTSSKQKTIQKGPN----------------KITLLDSNRAKNL----------------AITLRKVGKTPEEICKAIQMFDLRTLPVDFVECLMRFIPTEPEVKALRQYEKERKPLENLTDEDRFMMQFSKIERLMQKMTIMAFVGNFCESVQMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVREKYQQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYSMHGHN---------TLLKDFIQHNESKLKKLQDDAKIAQDAFDEAVKFFGE-SAKTTPPSVFFPVFVRFVKAYRQAEEENEARK 957
BLAST of Formin-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010834.1 (pep scaffold:Pmarinus_7.0:GL476428:81056:119857:-1 gene:ENSPMAG00000009817.1 transcript:ENSPMAT00000010834.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 217.238 bits (552), Expect = 8.764e-58 Identity = 163/437 (37.30%), Postives = 247/437 (56.52%), Query Frame = 2
Query: 137 SLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSL-RRIFDASQRNXXXXXXXXXXXXGINR-------NTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELE 1399
S+++ P + + Q +A +K EL+ + F+ KNP T I+ L+SY +T K + Q + Q+L EISLRTNH+ WV +FL ++ GL++L++Y+S + +T + GA + NG S ++SL R I D S +N+ + + ++ + R N+ K K+ V S K+ +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E++RF+ LM ++R+ +D NID+ V+ MQFINI+VHSV+++N RV+LQYEFT L LDS+L+KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE+ IS L E+L E E KI E E ++ +A KELE
Sbjct: 2 SMNLPPDKARLLRQYDAEKKWELICDQERFQVKNPPH------TYIQKLKSYLDPGVTRKKLRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLIEYLS-----------FAQYAVT----------FDIEGAEGAGNGTLSR-----SKSLDRSIEDLSGKNNGLHAAVCTTTAKMARHHLSLRYNSLPSRKTLKNSRLV--SQKDDVHVCIMCLRAIMNYQYGFNMVMAHPQCVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFERLMEYFRN------EDSNIDFMVACMQFINIVVHSVDDMNFRVHLQYEFTKLALDSYLEKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEEHISHLTEKLIDCENEAMAKIVELEKQLMQANKELE 398 HSP 2 Score: 184.111 bits (466), Expect = 2.008e-47 Identity = 135/412 (32.77%), Postives = 220/412 (53.40%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMAS---EAADRLLYQLPSFQETDMYRDITGES--LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISEN--ARRQ 3169
P+ W L+ Q GTVF E+D +I ++LD+D FE++FK T+D L + + + ++ Q +K++LL+ NR K + + L+ ++ E R AI FD+ + + + L LPS E + R E L+ LA+EDR + S I+R+ ++ ++++ F E L ++ + A S+ S K+KKILEI+LAFGN MN S+RG GF++QSLD+L E +S D K +L++YI+ ++ K+PDL F++EL Y+E A+ VS+ N++ EL G+D E S+ E+N T L F+ + R+ L + T+ A+ A+ V++FGE + +T P +FF LVRF+ ++K+A +N RRQ
Sbjct: 630 PVFNWVALKPNQINGTVFNELDDEKILEELDMDEFEEMFKTRA--------QGATVD---LCLSKIKMVHKTQ----------NKVTLLETNRAKNLAIT---------LRKGGLTTEEICR----AIQMFDLQTLRLDFVECLTRFLPSEAEVKLLRQYERERKPLDELADEDRFMLQFSKIERLTQRMTIMIFIGNFTENVQMLTPQLNAIIAASMSIKSSHKIKKILEIILAFGNYMNSSKRGAVYGFKLQSLDLLIETKSTDRKLTLLHYISNIVQHKYPDLVTFYNELRYIEKAAAVSMENVLQDVRELQRGMDLTKREFSM----HESN-----TLLREFLAPSEARLERLLSDTKTAQEAYNTVVQYFGE-NPKTTPPSVFFPLLVRFVKAYKQAELDNEMKRRQ 997
BLAST of Formin-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001635.1 (pep scaffold:Pmarinus_7.0:GL479577:17910:32690:1 gene:ENSPMAG00000001475.1 transcript:ENSPMAT00000001635.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 196.052 bits (497), Expect = 1.090e-54 Identity = 149/467 (31.91%), Postives = 236/467 (50.54%), Query Frame = 2
Query: 137 SLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXG---------INRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTR---EEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSD 1486
S+++ P Q + + +K EL+ + F+ KNP + Y+ +K + M + K Q + Q+L EISLRTNH+ WV +FL ++ GL++LVDY+ S Y A +++G + + +SL D + + S +S + NT + ++ AV ++ +H+C+ C R I+N Q G + + +N IT+ L + S +TK+L+L+LL+AVCL+ GGH ++L AF FK + + E+ RF+ LM ++ +D NID+ V+ MQFINI+VHSVE++NLRV+LQYEFT LGLD L+ L+E +RL Q+ AYLDN+ D LLEDAE + A + + LE I+ + + K EA R+ + EK+L S + + L S+I ++ L D
Sbjct: 5 SMNLPPDKAQLLQDYDVEKKWELVCDQERFQVKNPPHT---YIQQLKSHMEFSMARKQFKRRVQESTQVLREIEISLRTNHIGWVREFLNEENRGLDVLVDYLCH---------------------TQSSGTYDDAAAATTDSGATPSMAER-QKSLDGAVDEDAEHESSGGGLTSAASSVSRAAKQLLLRHNTLNRRWTFRNQKAVS---QDDVHVCIMCLRAIMNYQSGFNLVMSHPSCVNEITLSLNNRSPRTKALVLELLAAVCLVLGGHSKILAAFSNFKEVKQSCGEKNRFERLMEYF------GTEDNNIDFMVACMQFINIVVHSVEDMNLRVHLQYEFTELGLDGVLESLKETESERLLMQIQAYLDNVFDVGALLEDAETRTAALEHVDSLEDQIASVTRHM-------EEKELEAMARIAELEKQLMHGASALNSIEGLYRDASSRIHELESLLKD 430
BLAST of Formin-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000660.1 (pep scaffold:Pmarinus_7.0:GL482229:53:18716:-1 gene:ENSPMAG00000000600.1 transcript:ENSPMAT00000000660.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 151.754 bits (382), Expect = 2.072e-38 Identity = 107/304 (35.20%), Postives = 181/304 (59.54%), Query Frame = 2
Query: 755 CFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEG-GHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFL 1663
C R L Q G + + +N I + L + + +T++L+L+LL+AVCL+ G GH+ L AFD FK + +E RF+ L+ +++ D+ ++D+ V+ MQFINI+VHSVE++N RV+LQYEFT LG+D +L+KL++ ++L Q+ AYLDN+ D +VL++DAE K A + ++L + +S LQE L E +I E E ++ KE+EK Q E V +LR +++ ++ L R+S++++ + ++++ + V + + PA P ++ D P+SD S EF+
Sbjct: 3 CVRVPL--QYGFEKVLSHPQCVNEIALSLNNKNQRTRTLVLELLAAVCLVRGEGHDTTLAAFDNFKEVCKERHRFERLLTYFKD------DESSMDFMVACMQFINIVVHSVEHMNYRVHLQYEFTKLGMDEYLEKLKKTESEKLQVQIQAYLDNVFDVAVLVDDAETKNAAVERVQQLNEQVSHLQENLQEQEDAAVSRIVELEKKLLNYCKEVEKLQVSLKEERGQVSTLRHSVKEKDLALR-RQSELEKRL----EEMEAHRSSIVLSQDGLPSSLPAPP--SAATDSTPTSDRA-SGEFI 290 HSP 2 Score: 58.9214 bits (141), Expect = 5.245e-9 Identity = 61/239 (25.52%), Postives = 103/239 (43.10%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQ----SDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADRL-LYQ--LPSFQETDMYRDITGE--SLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEI 2635
P+ W L+ Q GTVF ++D ++ + LD+D FE++FK P+ TI Q+ G N + K+SLLD NR + + +I+ R+ R + A+ F++ +RL Q +P+ E + R + S LA E+R + ++R+ ++ +L+M F +T L + + A S+ SQK KKILE+
Sbjct: 397 PVFNWTALKPSQVNGTVFTDMDDEELLQVLDMDSFEELFKTKA------QGPVATI----------------QVDGPRCNAAQPKVAPKVSLLDANRARNL----------------AITLRKTARSHGEICKAVQTFNVQELPVERLECLQRFVPTESEAMLLRQYERDLRSPEDLAEEERFMLQFGRVERLSQRITVMLFMGNFMDTVSRLTPFVNAIIAASLSIKSSQKFKKILEV 597
BLAST of Formin-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000664.1 (pep scaffold:Pmarinus_7.0:GL482229:65:18719:-1 gene:ENSPMAG00000000600.1 transcript:ENSPMAT00000000664.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 142.51 bits (358), Expect = 1.837e-35 Identity = 77/190 (40.53%), Postives = 126/190 (66.32%), Query Frame = 2
Query: 755 CFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEG-GHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQL 1321
C R L Q G + + +N I + L + + +T++L+L+LL+AVCL+ G GH+ L AFD FK + +E RF+ L+ +++ D+ ++D+ V+ MQFINI+VHSVE++N RV+LQYEFT LG+D +L+KL++ ++L Q+ AYLDN+ D +VL++DAE K A + ++L + +S + +L
Sbjct: 4 CVRVPL--QYGFEKVLSHPQCVNEIALSLNNKNQRTRTLVLELLAAVCLVRGEGHDTTLAAFDNFKEVCKERHRFERLLTYFKD------DESSMDFMVACMQFINIVVHSVEHMNYRVHLQYEFTKLGMDEYLEKLKKTESEKLQVQIQAYLDNVFDVAVLVDDAETKNAAVERVQQLNEQVSHVSARL 185 HSP 2 Score: 57.7658 bits (138), Expect = 1.338e-8 Identity = 59/245 (24.08%), Postives = 101/245 (41.22%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQ----SDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGESLNVL--------------ANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEI 2635
P+ W L+ Q GTVF ++D ++ + LD+D FE++FK P+ TI Q+ G N + K+SLLD NR + + +I+ R+ R ++ ++ R L +LP + + R + ES +L A E+R + ++R+ ++ +L+M F +T L + + A S+ SQK KKILE+
Sbjct: 373 PVFNWTALKPSQVNGTVFTDMDDEELLQVLDMDSFEELFKT------KAQGPVATI----------------QVDGPRCNAAQPKVAPKVSLLDANRARNL----------------AITLRKTAR------SHGEICKAVQTRSLMKLPVERLECLQRFVPTESEAMLLRQYERDLRSPEDLAEEERFMLQFGRVERLSQRITVMLFMGNFMDTVSRLTPFVNAIIAASLSIKSSQKFKKILEV 573
BLAST of Formin-like protein vs. Ensembl Sea Lamprey
Match: daam1a (dishevelled associated activator of morphogenesis 1a [Source:ZFIN;Acc:ZDB-GENE-030911-6]) HSP 1 Score: 126.716 bits (317), Expect = 1.116e-29 Identity = 107/409 (26.16%), Postives = 189/409 (46.21%), Query Frame = 2
Query: 1997 GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEH----------------EYDVP----PLDTIDGKGLE---IQRERNLNDNQLSG----DGANDQSDKISLLDPNR-QKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDK-WSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSF 3136
GT++ E+D + + LDL E++F + +DV P + K L Q E NL +L N ++ ++S++D R Q C+ LL +S E R L ++ + ++LL +P + D+ + E + +A DR + +S I + +L+A+ + F E + K+ + LA R V S++L+++LE+VLA GN MN +RG A GF+I SL+ + + +S DK +L++Y+ +E+KFPD+ +L++V +A++V+L + + GL V EL + D + + +F+ + L + +AK F K+V FGE+ +T P+ FFG F+ +F
Sbjct: 467 GTIWSELDDQRAFRVLDLQDIERVFSAYQRQQLACVKKNQIILQEKQCSFDVGDKYRPFNGTRRKTLSKRASQLEANLAHKELGSTEDLHHGNKRAKELSVIDGRRAQNCVI----------LLSKLKMSNEEIKRALMRMDEQEELPKDMLEQLLKFVPEKSDVDVLEEHRHE-IERMARADRFLFDMSRIPHYQQRLQALFFKKKFAERLGECKPKVEAILLASREVSRSRRLRQLLELVLALGNYMNKGQRGNAYGFKISSLNKIADTKSSTDKNINLLHYLIIVVEKKFPDVLGISDDLQHVPEAAKVNLTEMEKEINNIKIGLKAVEAELEFQRTHASAIGDRFISVMSDFITVASFSFSELEDLLSEAKEKFNKSVSHFGEEGGRT-QPEEFFGMFDAFLSAF 863 HSP 2 Score: 77.7962 bits (190), Expect = 1.107e-14 Identity = 49/157 (31.21%), Postives = 86/157 (54.78%), Query Frame = 2
Query: 746 CLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHS---VENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAY 1207
+ C + ++NN +G + ++INVI+ L + TK +L++L AVCL+ GGH +VL+A ++ E TL+ + D+ ++ A+ M FIN I+++ EN+ RV+L+YEF +LG+ S + KL+ L+R +D +
Sbjct: 35 VIGCIKALMNNSQGRAHVLAHPESINVISQSLSSEN-ATKVAVLEILGAVCLVPGGHRKVLQAMLRYQQHAAERTLLQTLITELDRNTGKYRDEVSLKTAI--MSFINAILNAGTGQENLEFRVHLRYEFLMLGIQSLVDKLRSHENATLDRHLDFF 188
BLAST of Formin-like protein vs. Ensembl Yeast
Match: BNI1 (Formin; polarisome component; nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables; recruited to the division site in a Glc7p/Ref2p dependent manner following release of Bnr1p; functionally redundant with BNR1 [Source:SGD;Acc:S000005215]) HSP 1 Score: 78.1814 bits (191), Expect = 6.590e-15 Identity = 53/221 (23.98%), Postives = 112/221 (50.68%), Query Frame = 2
Query: 2504 KLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRV--AEELSLIKNAVENNP-DLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISEN 3157
++ A+ + +++ Y L K+R V A ++ ES L+ + ++LA GN MND+ + +A GF++ +L L + + + +NY+ + +P +F SELE V D +VS+ L+ ++ S + V + E+ + ++ + +P D + + + + E + +LL ++ + + F + +GE + FF F++ +KKA ++N
Sbjct: 1528 RMRALTVVTSYEREYNELLAKLRKVDKAVSALQESDNLRNVFNVILAVGNFMNDTSK-QAQGFKLSTLQRLTFIKDTTNSMTFLNYVEKIVRLNYPSFNDFLSELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGNLSDSSKFHPLDKVLIKTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTYGEDSGDKFAKISFFKKFADFINEYKKAQAQN 1747
BLAST of Formin-like protein vs. Ensembl Yeast
Match: BNR1 (Formin; nucleates the formation of linear actin filaments; involved in processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables; activity is regulated by Hof1p and by the Bud14p-Kel1p-Kel2p complex; dephosphorylated and delocalized from the division site in a Glc7p/Ref2p-dependent manner; functionally redundant with BNI1 [Source:SGD;Acc:S000001421]) HSP 1 Score: 73.1738 bits (178), Expect = 2.601e-13 Identity = 62/254 (24.41%), Postives = 120/254 (47.24%), Query Frame = 2
Query: 2429 GESLNVLANEDRLVALLSCID---RVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSP-DDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENN---PDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
G++++ L DR+ L CI+ + +++L + ++ Y+ L K++ + A + S K K ++ I+ GN MN + G +++SL L RS D S +++I I K+PD+ F +L+ +ED ++SL ++ + E ++ + + + K + E N D I ++ + T+ LL Q + I K ++++GE S + FF + F+ FKK EN ++
Sbjct: 1026 GKAVSDLQRADRIFLEL-CINLRFYWNARSKSLLTLSTYERDYYDLIFKLQKIDDAISHLNRSPKFKSLMFIITEIGNHMN---KRIVKGIKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKNIEDLGKISLEHVESECHEFHKKIEDLVTQFQVGKLSKEENLDPRDQIIKKVKFKINRAKTKSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKENIEKE 1275
BLAST of Formin-like protein vs. Ensembl Nematostella
Match: EDO32868 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STU3]) HSP 1 Score: 126.331 bits (316), Expect = 2.845e-29 Identity = 103/399 (25.81%), Postives = 193/399 (48.37%), Query Frame = 2
Query: 1973 WNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECR-SPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNP-DLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISEN 3157
W+ L + + GTV+ +ID +++ ++DL+ F+++F +G E Q ++ D+ + ++SL+D R + +++T L +S E + + +++ + ++LL +P+ E ++ + E N A D+ + +S I E +L+A+ + F E L+ K++ V +AC+ V S++++ +LE++LAFGN MN RG A GF++ SL+ + + + S + + +L+NY+ +E+ +PD+ +L V A++V+L L + L L V +EL E P D + +FV+ + E+ K F K V+ FGE D + S D FFG F+ SF +A +N
Sbjct: 692 WSKLPDSKIKGTVWTDIDDTKVYNEMDLEDFDRMFSAY----------------QGKENQGIKDFTDSAA-------KPKELSLIDSRRAQNCGILLTKL---------KLSDEEITKAILTIDEEEELSKDMVEQLLKYVPTAAEKNLLNENNKEKDN-FARADKFLYDMSRIVHYEQRLKALFFKKKFPERMGDLKPKVQAVIMACKEVTRSKRIRTLLEVILAFGNYMNRGARGNATGFKLASLNRIVDTKSSANSRITLLNYLVTVLEKSYPDVLKLEEDLANVRTAAKVNLAELESEIVALRKELKEVEKELDFQTRKREKIPGDKFVDVIGSFVKVAQFSCCEVEEAWEELKQKFFKAVKLFGE-DPKNLSSDQFFGIFNVFLVSFAEAKHQN 1056 HSP 2 Score: 75.8702 bits (185), Expect = 8.164e-14 Identity = 44/157 (28.03%), Postives = 82/157 (52.23%), Query Frame = 2
Query: 746 CLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVH---SVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAY 1207
+ CF+ ++N+ G + I++I L+ + +TK +L++L AVCL+ GGH++ L A F+ E RF TL+ + +++N+ A+ M FIN + E + RV+L++EF +LG+ ++KL+ L R ++ +
Sbjct: 193 VIGCFKALMNSSHGRAHVLAHPTCIDIIAQSLLTENIKTKIQVLEILGAVCLVPGGHKKALDAMTHFQKFAEERTRFQTLVNDLDRSTGVYKEEFNLKIAI--MSFINAALKYGAGAEYLEFRVHLRFEFLMLGIQPVIEKLRTMDNATLTRHLNFF 347
BLAST of Formin-like protein vs. Ensembl Nematostella
Match: EDO35335 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLQ1]) HSP 1 Score: 95.1301 bits (235), Expect = 1.198e-19 Identity = 76/271 (28.04%), Postives = 130/271 (47.97%), Query Frame = 2
Query: 2351 MASEAADRLLYQLPSFQETDMYRDITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMN-DSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKF-PDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISEN 3157
++ A + LL LPS ++ + ++ + ++ L+ ++ +S I ++E +L +L+ F E + + ACR V S K K+LE++L GN MN SR IGF I L L +S D + +L+++IA +E K+ ++ F +EL +VE A +VS L + +S L ++ +EL K N D + F +V++L + F +E+F D + S + FFG L FMD + + EN
Sbjct: 611 LSESAIESLLKYLPSPEQMEQLSNMK-DQISELSEPEQFAVHISDIKKLEQRLNCLLFRTRFPEEMSDTKPGVVNATAACREVKTSPKFAKLLELILLMGNYMNTGSRNEGTIGFEISYLTKLSSTKSVDGQRNLLHFIADAVENKYSSEIAGFENELGHVEAAGKVSEEILGKSISNMSANLRKIEKELE-AKQQNTNPEDRFHDAMKEFYSSAKDQVDVLVEMHKNMVTMFKDVLEFFC-MDPKKTSMEEFFGDLKTFMDQYSQCKKEN 878 HSP 2 Score: 63.5438 bits (153), Expect = 5.345e-10 Identity = 41/165 (24.85%), Postives = 90/165 (54.55%), Query Frame = 2
Query: 716 GDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQT-KSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAY 1207
G K H C++C + +NN+ G Q+ + +D + ++ + P+Y + + ++ +++AVCL++ H+R ++A + + E+ RF ++ L D + V+ +QFIN ++ + ++++ R++L+ EF GL+ + L++ D LN Q+D +
Sbjct: 103 GSVEKRIQHECVRCLKAYMNNKYGLQLMLKSEDGLTLLARSM-DPNYPSMMTDVVKVMAAVCLVK--HDRAVEAMTVCGEL-EEKGRFSKIVD--------ALHDDHTSLKVACIQFINALISTPDDLDFRLHLRNEFVREGLNDAFQDLRDLENDDLNVQLDIW 255
BLAST of Formin-like protein vs. Ensembl Nematostella
Match: EDO48372 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJG2]) HSP 1 Score: 77.7962 bits (190), Expect = 2.949e-14 Identity = 86/322 (26.71%), Postives = 160/322 (49.69%), Query Frame = 2
Query: 2495 VEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMN--DSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEEL-SLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTE---------QAKIA--FVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISEN-ARRQMGDXXXXXXXXXXXXXXPKGDQTRKKNRTRQINAD----GIMDEIMAGLDYQPLQAGLHARRGKRDN---TDSPETSIYQEH 3394
V+ +L+A+L+ FD+ ++ + V A + S KL+++LE+VL GN MN ++R A F+I L L ++ D+K +L+N++ IEE+ P+L + +L V A++VS L ++LS + + ++L S A + D ++N + ++T+ + +TE Q K+ F V++FGEKD + + + FFG F+ F A++ N ++++ +E +++ + ++ K+ + R+I+ D DE+M LD ARR K ++ T SP T+I E+
Sbjct: 1126 VKKRLKAMLFRAQFDDKCDEVKPDLEAVIDAAAELRTSDKLQRVLELVLMTGNYMNKGNTRIAGAQAFKISYLTKLNTTKTTDNKSTLLNFLVQKIEERCPELLDVKDDLRTVPIAAKVSGQLLATEVQDLSRRMKGIKDDLISFQALASQKEEDRFTEVVINIITSSLTKCQNIIEETEGKLEELLDLQKKMNEDFRDVVKFFGEKDSKMTT-EEFFGIFAAFLVHFNMAVNHNITKKKLQEEQAKREER---------NKLFKELKQRKISVDEEVEQAKDELMKSLD---------ARRPKSNDQATTISPTTAITSEN 1428
BLAST of Formin-like protein vs. Ensembl Nematostella
Match: EDO48258 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJG3]) HSP 1 Score: 73.1738 bits (178), Expect = 4.209e-13 Identity = 61/195 (31.28%), Postives = 92/195 (47.18%), Query Frame = 2
Query: 2567 IRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRS-PDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAI 3148
+ TV A + + S KL L++VL GN MN S+ GFR+ L L +S PD S ++YI I K P+L EL +VE AS+VS L EEL ++ + ++L I + + F + L QA+++F T+E+FGE+ + S FFG + F+ FK A+
Sbjct: 419 LTTVIEANKEIRNSTKLSDYLQMVLTVGNFMNGSQTA---GFRVAFLTKLVFIKSTPDKNVSFLDYITRQIIRKNPELALLTDELLHVEKASKVSFRTLDLDIEELREEVEILEDDLDKIAKTEIHEDSKFMEAIELFTHHARAQFQSLVELRHQAELSFATTLEYFGEE--TSISSAQFFGLISTFLCHFKDAV 608
BLAST of Formin-like protein vs. Ensembl Nematostella
Match: EDO29831 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2I4]) HSP 1 Score: 60.8474 bits (146), Expect = 5.292e-10 Identity = 41/165 (24.85%), Postives = 90/165 (54.55%), Query Frame = 2
Query: 716 GDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQT-KSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAY 1207
G K H C++C + +NN+ G Q+ + +D + ++ + P+Y + + ++ +++AVCL++ H+R ++A + + E+ RF ++ L D + V+ +QFIN ++ + ++++ R++L+ EF GL+ + L++ D LN Q+D +
Sbjct: 63 GSVEKRIQHECVRCLKAYMNNKYGLQLMLKSEDGLTLLARSM-DPNYPSMMTDVVKVMAAVCLVK--HDRAVEAMTVCGEL-EEKGRFSKIVD--------ALHDDHTSLKVACIQFINALISTPDDLDFRLHLRNEFVREGLNDAFQDLRDLENDDLNVQLDIW 215
BLAST of Formin-like protein vs. Ensembl Medaka
Match: fmnl2a (formin like 2 [Source:NCBI gene;Acc:101172369]) HSP 1 Score: 362.073 bits (928), Expect = 5.228e-106 Identity = 326/1100 (29.64%), Postives = 531/1100 (48.27%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNG---TNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVD--MNDSQPALNNDTVETHKGASNIPHSAVSTNK----PKLPHTPLKS---KEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMD-------VSITSVAGDAPL--------IKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGESLNV--LANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
MGN K + P P++ E E+R+ + + S+++ P + + Q + +K EL+ + F+ KNP T ++ LRSY + K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y++ + + +G NT + +S + S + S ++RR + S + + + I RN++ + +S C +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E +RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS + E+L E E KI E E ++ + K+LE + + S ++SLR +++ + + R+S+++++I +L Q G I + KK D+ + + E L + PA+N+D G + P LP+ PL S P A+D P+ M+ + + SV P+ W L+ Q GTVF EID +I + L++D FE++FK + PP+D K IQ+ K++LLD NR K + +I+ R+ G+ + AI FD+ + D L+ P+ E ++R E V L NEDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA ++EK+ + F++EL YVE A+ VSL N + +EL G+D E S+ + T L +F+ N +++ L++ + A+ AF + +++FGE +T P +FF VRF+ ++++A +N +R+
Sbjct: 1 MGNAGSMDQTTYFKGHGVPTKLPMPESGE-LEERFAIVLNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYLQKLRSYLDPAVPRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLA-----------FAQYAVNYDGDSVENTEDALDKSKTWSRSIEDLHRGGSFHHGGTMRR------GGTLPPSTTGNGITRIGRNSTLRYSTMSIRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCVETQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDDYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHMTEKLQDTENEAMSKIVELEKQLMQRNKDLEAIREAYKDTSSQIQSLRQMLKEKDEAIQ-RQSNLEKKIHELEKQ-----------GTIKIHKK-------GDGDISILASSPAGVEGLTGSTATGNGPAVNSDHSGAGGGMAGPPPPPPPPPPLPVNGTLPNGPLPSVSVPAQPPPPPPPPPPPPGLASDLFPSAPPPPPMPPPLPGCGTPTVIMNSGLAEGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----KAQGPPIDFNVSKQKVIQK----------------GPSKVTLLDSNRAKNL----------------AITLRKVGKTTEEICKAIQLFDLRTLPVDFVECLMRFQPTENEVKVFRQFEKERKPVESLTNEDRFMMQFSKIERLMQKMTIMAFIGNFSESVLMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVKEKYSQVSLFYNELNYVEKAAGVSLDNALLDVKELQRGMDLTKREYSMHGHN---------TMLKDFITHNESKLKKLQDDAKIAQDAFDEVLKFFGENS-KTTPPSVFFPVFVRFVKAYRQAEEDNEQRK 1004
BLAST of Formin-like protein vs. Ensembl Medaka
Match: fmnl2a (formin like 2 [Source:NCBI gene;Acc:101172369]) HSP 1 Score: 358.992 bits (920), Expect = 8.730e-105 Identity = 317/1057 (29.99%), Postives = 516/1057 (48.82%), Query Frame = 2
Query: 125 VFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNG---TNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVD--MNDSQPALNNDTVETHKGASNIPHSAVSTNK----PKLPHTPLKS---KEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMDVSITSVAGDAPL--------IKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGESLNV--LANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
+F S+++ P + + Q + +K EL+ + F+ KNP T ++ LRSY + K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y++ + + +G NT + +S + S + S ++RR + S + + + I RN++ + +S C +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E +RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS + E+L E E KI E E ++ + K+LE + + S ++SLR +++ + + R+S+++++I +L Q G I + KK D+ + + E L + PA+N+D G + P LP+ PL S P A+D P+ M+ + +V P+ W L+ Q GTVF EID +I + L++D FE++FK + PP+D K IQ+ K++LLD NR K + +I+ R+ G+ + AI FD+ + D L+ P+ E ++R E V L NEDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA ++EK+ + F++EL YVE A+ VSL N + +EL G+D E S+ + T L +F+ N +++ L++ + A+ AF + +++FGE +T P +FF VRF+ ++++A +N +R+
Sbjct: 40 LFQNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYLQKLRSYLDPAVPRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLA-----------FAQYAVNYDGDSVENTEDALDKSKTWSRSIEDLHRGGSFHHGGTMRR------GGTLPPSTTGNGITRIGRNSTLRYSTMSIRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCVETQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDDYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHMTEKLQDTENEAMSKIVELEKQLMQRNKDLEAIREAYKDTSSQIQSLRQMLKEKDEAIQ-RQSNLEKKIHELEKQ-----------GTIKIHKK-------GDGDISILASSPAGVEGLTGSTATGNGPAVNSDHSGAGGGMAGPPPPPPPPPPLPVNGTLPNGPLPSVSVPAQPPPPPPPPPPPPGLASDLFPSAPPPPPMPPPLPGCGTPTVIMNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----KAQGPPIDFNVSKQKVIQK----------------GPSKVTLLDSNRAKNL----------------AITLRKVGKTTEEICKAIQLFDLRTLPVDFVECLMRFQPTENEVKVFRQFEKERKPVESLTNEDRFMMQFSKIERLMQKMTIMAFIGNFSESVLMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVKEKYSQVSLFYNELNYVEKAAGVSLDNALLDVKELQRGMDLTKREYSMHGHN---------TMLKDFITHNESKLKKLQDDAKIAQDAFDEVLKFFGENS-KTTPPSVFFPVFVRFVKAYRQAEEDNEQRK 1001
BLAST of Formin-like protein vs. Ensembl Medaka
Match: fmnl2a (formin like 2 [Source:NCBI gene;Acc:101172369]) HSP 1 Score: 353.214 bits (905), Expect = 8.064e-103 Identity = 318/1064 (29.89%), Postives = 517/1064 (48.59%), Query Frame = 2
Query: 125 VFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNG---TNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVD--MNDSQPALNNDTVETHKGASNIPHSAVSTNK----PKLPHTPLKS---KEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMD-------VSITSVAGDAPL--------IKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGESLNV--LANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
+F S+++ P + + Q + +K EL+ + F+ KNP T ++ LRSY + K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y++ + + +G NT + +S + S + S ++RR + S + + + I RN++ + +S C +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E +RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS + E+L E E KI E E ++ + K+LE + + S ++SLR +++ + + R+S+++++I +L Q G I + KK D+ + + E L + PA+N+D G + P LP+ PL S P A+D P+ M+ + + SV P+ W L+ Q GTVF EID +I + L++D FE++FK + PP+D K IQ+ K++LLD NR K + +I+ R+ G+ + AI FD+ + D L+ P+ E ++R E V L NEDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA ++EK+ + F++EL YVE A+ VSL N + +EL G+D E S+ + T L +F+ N +++ L++ + A+ AF + +++FGE +T P +FF VRF+ ++++A +N +R+
Sbjct: 40 LFQNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYLQKLRSYLDPAVPRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLA-----------FAQYAVNYDGDSVENTEDALDKSKTWSRSIEDLHRGGSFHHGGTMRR------GGTLPPSTTGNGITRIGRNSTLRYSTMSIRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCVETQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDDYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHMTEKLQDTENEAMSKIVELEKQLMQRNKDLEAIREAYKDTSSQIQSLRQMLKEKDEAIQ-RQSNLEKKIHELEKQ-----------GTIKIHKK-------GDGDISILASSPAGVEGLTGSTATGNGPAVNSDHSGAGGGMAGPPPPPPPPPPLPVNGTLPNGPLPSVSVPAQPPPPPPPPPPPPGLASDLFPSAPPPPPMPPPLPGCGTPTVIMNSGLAEGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----KAQGPPIDFNVSKQKVIQK----------------GPSKVTLLDSNRAKNL----------------AITLRKVGKTTEEICKAIQLFDLRTLPVDFVECLMRFQPTENEVKVFRQFEKERKPVESLTNEDRFMMQFSKIERLMQKMTIMAFIGNFSESVLMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVKEKYSQVSLFYNELNYVEKAAGVSLDNALLDVKELQRGMDLTKREYSMHGHN---------TMLKDFITHNESKLKKLQDDAKIAQDAFDEVLKFFGENS-KTTPPSVFFPVFVRFVKAYRQAEEDNEQRK 1008
BLAST of Formin-like protein vs. Ensembl Medaka
Match: fmnl2a (formin like 2 [Source:NCBI gene;Acc:101172369]) HSP 1 Score: 353.214 bits (905), Expect = 8.221e-103 Identity = 318/1064 (29.89%), Postives = 517/1064 (48.59%), Query Frame = 2
Query: 125 VFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNG---TNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVD--MNDSQPALNNDTVETHKGASNIPHSAVSTN----KPKLPHTPLKS---KEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMD-------VSITSVAGDAPL--------IKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADR---LLYQLPSFQETDMYRDITGESLNV--LANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
+F S+++ P + + Q + +K EL+ + F+ KNP T ++ LRSY + K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y++ + + +G NT + +S + S + S ++RR + S + + + I RN++ + +S C +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E +RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS + E+L E E KI E E ++ + K+LE + + S ++SLR +++ + + R+S+++++I +L Q G I + KK D+ + + E L + PA+N+D G + P LP+ PL S P A+D P+ M+ + + SV P+ W L+ Q GTVF EID +I + L++D FE++FK + PP+D K IQ+ K++LLD NR K + +I+ R+ G+ + AI FD+ + D L+ P+ E ++R E V L NEDR + S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA ++EK+ + F++EL YVE A+ VSL N + +EL G+D E S+ + T L +F+ N +++ L++ + A+ AF + +++FGE +T P +FF VRF+ ++++A +N +R+
Sbjct: 40 LFQNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPH------TYLQKLRSYLDPAVPRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLA-----------FAQYAVNYDGDSVENTEDALDKSKTWSRSIEDLHRGGSFHHGGTMRR------GGTLPPSTTGNGITRIGRNSTLRYSTMSIRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCVETQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDDYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHMTEKLQDTENEAMSKIVELEKQLMQRNKDLEAIREAYKDTSSQIQSLRQMLKEKDEAIQ-RQSNLEKKIHELEKQ-----------GTIKIHKK-------GDGDISILASSPAGVEGLTGSTATGNGPAVNSDHSGAGGGMAGPPPPPPPPPPLPVNGTLPNGPLPSVSVPAQPPPPPPPPPPPPGLASDLFPSAPPPPPMPPPLPGCGTPTVIMNSGLAEGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----KAQGPPIDFNVSKQKVIQK----------------GPSKVTLLDSNRAKNL----------------AITLRKVGKTTEEICKAIQLFDLRTLPVDFVECLMRFQPTENEVKVFRQFEKERKPVESLTNEDRFMMQFSKIERLMQKMTIMAFIGNFSESVLMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVKEKYSQVSLFYNELNYVEKAAGVSLDNALLDVKELQRGMDLTKREYSMHGHN---------TMLKDFITHNESKLKKLQDDAKIAQDAFDEVLKFFGENS-KTTPPSVFFPVFVRFVKAYRQAEEDNEQRK 1008
BLAST of Formin-like protein vs. Ensembl Medaka
Match: fmnl2a (formin like 2 [Source:NCBI gene;Acc:101172369]) HSP 1 Score: 337.806 bits (865), Expect = 1.754e-97 Identity = 314/1059 (29.65%), Postives = 510/1059 (48.16%), Query Frame = 2
Query: 125 VFIQSLDVTPQNIQNIDQLEAPQKIELLLN---FEAKNPKCSAFHYVTLIKGLRSY---KMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFL--KHSGLEILVDYMSQILLHLIKSEEMQIFPITMNG---TNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKEC----LHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVD--MNDSQPALNNDTVETHKGASNIPHSAVSTN----KPKLPHTPLKS---KEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMD-------VSITSVAGDAPL--------IKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRP---LACAITNFDMASEAADRLLYQLPSFQETDMYRDITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQ 3169
+F S+++ P + + Q + +K EL+ + F+ KNP H T ++ LRSY + K + Q + Q+L EISLRTNH+ WV +FL ++ GL++LV+Y++ + + +G NT + +S + S + S ++RR + S + + + I RN++ + +S C +H+C+ C R I+N Q G M + +N I + L + + +TK+L+L+LL+AVCL+ GGHE +L AFD FK + E +RF+ LM ++++ +D NID+ V+ MQFINI+VHSVE++N RV+LQY+FT L LD +L KL+ D+L Q+ AYLDN+ D LLEDAE K A + E LE++IS + E+L E E KI E E ++ + K+LE + + S ++SLR +++ + + R+S+++++I +L Q G I + KK D+ + + E L + PA+N+D G + P LP+ PL S P A+D P+ M+ + + SV P+ W L+ Q GTVF EID +I + L++D FE++FK + PP+D K IQ+ K++LLD NR K + +I+ R+ G+ + AI FD+ + D + L FQ T+ NE S I+R+ K+ + ++ F E+ L ++ V A S+ SQKLKKILEI+LA GN MN S+RG GF++QSLD+L + +S D K +L++YIA ++EK+ + F++EL YVE A+ VSL N + +EL G+D E S+ + T L +F+ N +++ L++ + A+ AF + +++FGE +T P +FF VRF+ ++++A +N +R+
Sbjct: 40 LFQNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPP----H--TYLQKLRSYLDPAVPRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLA-----------FAQYAVNYDGDSVENTEDALDKSKTWSRSIEDLHRGGSFHHGGTMRR------GGTLPPSTTGNGITRIGRNSTLRYSTMSIRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCVETQRFERLMEYFKN------EDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLCLDDYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHMTEKLQDTENEAMSKIVELEKQLMQRNKDLEAIREAYKDTSSQIQSLRQMLKEKDEAIQ-RQSNLEKKIHELEKQ-----------GTIKIHKK-------GDGDISILASSPAGVEGLTGSTATGNGPAVNSDHSGAGGGMAGPPPPPPPPPPLPVNGTLPNGPLPSVSVPAQPPPPPPPPPPPPGLASDLFPSAPPPPPMPPPLPGCGTPTVIMNSGLAEGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKT-----KAQGPPIDFNVSKQKVIQK----------------GPSKVTLLDSNRAKNL----------------AITLRKVGKTTEEICKAIQLFDLRTLPVD-FVECLMRFQPTE--------------NE------FSKIERLMQKMTIMAFIGNFSESVLMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKLTLLHYIANVVKEKYSQVSLFYNELNYVEKAAGVSLDNALLDVKELQRGMDLTKREYSMHGHN---------TMLKDFITHNESKLKKLQDDAKIAQDAFDEVLKFFGENS-KTTPPSVFFPVFVRFVKAYRQAEEDNEQRK 982
BLAST of Formin-like protein vs. Planmine SMEST
Match: SMESG000044336.1 (SMESG000044336.1) HSP 1 Score: 2177.52 bits (5641), Expect = 0.000e+0 Identity = 1125/1126 (99.91%), Postives = 1126/1126 (100.00%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFXXXXXXXXXXXXDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVDMNDSQPALNNDTVETHKGASNIPHSAVSTNKPKLPHTPLKSKEHLVADTQPLAKDEQHATDSLDLVXXXXXXXXXXXXXSRPSPSMDVSITSVAGDAPLIKWNILRNQQGTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDXXXXXXXXXXXXXXPKGDQTRKKNRTRQINADGIMDEIMAGLDYQPLQAGLHARRGKRDNTDSPETSIYQEH 3394
MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNSTRMSCSKSRSSGINRNTSSVSK+SKSHSAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSLLLDLLSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFEAEKARKIKEAEDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVDMNDSQPALNNDTVETHKGASNIPHSAVSTNKPKLPHTPLKSKEHLVADTQPLAKDEQHATDSLDLVININEKHNKEHKKSRPSPSMDVSITSVAGDAPLIKWNILRNQQGTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDENNRKKNKERKINEPKGDQTRKKNRTRQINADGIMDEIMAGLDYQPLQAGLHARRGKRDNTDSPETSIYQEH
Sbjct: 1 MGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGLRSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNSTRMSCSKSRSSGINRNTSSVSKNSKSHSAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSLLLDLLSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDISLLQEQLTLFEAEKARKIKEAEDRVRKAEKELEKAQSREDELSLLVESLRSKIRDINVNLSDRESDMKREITDLHDQLKKLNPAAVQNGNIHVKKKPAVPVRQSSNDVKPSSDNERSKEFLVDMNDSQPALNNDTVETHKGASNIPHSAVSTNKPKLPHTPLKSKEHLVADTQPLAKDEQHATDSLDLVININEKHNKEHKKSRPSPSMDVSITSVAGDAPLIKWNILRNQQGTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGESLNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISENARRQMGDENNRKKNKERKINEPKGDQTRKKNRTRQINADGIMDEIMAGLDYQPLQAGLHARRGKRDNTDSPETSIYQEH 1126
BLAST of Formin-like protein vs. Planmine SMEST
Match: SMESG000040024.1 (SMESG000040024.1) HSP 1 Score: 364.385 bits (934), Expect = 1.185e-107 Identity = 207/433 (47.81%), Postives = 285/433 (65.82%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPP--PQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGL---RSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDI 1300
MG+ S P+ K+ NS P NL+ FEKRW FIQSLDV P+N++ IDQL+ QK +LLLNFE+KNPK SAFHYVTLIK L +S + + +K+ D+ + +LSATE+SLRTN+V+WVYDFL ++GLE+L+DYMS+ L+ + + NY++ + N ++SD + S +F + + N I R +S V+K S +V +S+K LH LKC R ILNNQ+GC+MAF + I+VI +CL+HP+YQTK+L+L+ L+A+CLI G ++VL AF+ FK +T E +RFDTL+ ++R HET +DDYNID+ VS QFINI+VHS E+INLRVYLQ EFT+LGLD F +KL+ER GDRL +QV AY N VD ++LLED+E KE + + E+LE +
Sbjct: 1 MGSTSSKST-PQYKFINSGEGRLEMRPTNLQ-FEKRWDTFIQSLDVGPENVRQIDQLDPDQKEQLLLNFESKNPKYSAFHYVTLIKALQTGKSIRKSFNKKPDD--DPVHVLSATEVSLRTNNVDWVYDFLNNNGLEVLLDYMSKTLVLFL------------------NINYKNIETKKTLN-LQSDTKTHLSSS--DLFKSKKFNCCA---------SIKRRSSVVTKFQNSKDSVNESVKNSLHQGLKCMRAILNNQRGCEMAFVHSRAIDVIALCLLHPNYQTKTLVLETLAAICLIVNGLQKVLAAFEYFKEITGESRRFDTLITYFRDHETFKVDDYNIDFMVSCTQFINIVVHSGEDINLRVYLQQEFTILGLDDFYRKLEERSGDRLKKQVAAYNGNRVDVAILLEDSETKETVLLDYEKLEHEF 399 HSP 2 Score: 273.478 bits (698), Expect = 6.460e-76 Identity = 171/477 (35.85%), Postives = 259/477 (54.30%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGES---LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISE-NARRQMGDXXXXXXXXXXXXXXPKGD----QTRKK-----NRTRQINADGIMDEIMAGLDYQPLQAGLHARRG 3346
P+ W++L+NQQ GTVF ++ + +L+ + FE IFK+ P+ D+I ++ N S + + +K +LLD ++ +C+ +++ +L QEKL H I L +I +++ E ADR+LYQLP+ + YR +N L +EDRL+ L ++R++ KLE ++Y+ F E Y +L EK+ V A +V SQKLK+ILEI+LA+GN MN SRRG GFR+QSLD+L + +S D W+LM + +E KF +L +F E+ +VE AS++ + + L G+ +V +E++ N P RL F +N L AK F++ EWFGE+ +PD+FFG RF ++FKK++ + RR N +E +PK + RKK NRTRQINADGIMD+I+AGLD PLQA +H +R
Sbjct: 552 PVFNWSVLKNQQLKGTVFVSMNDEVLYDKLEFEKFENIFKLNPVG--------DSIPN---------GVDSNDSSEKTSKRKPEKKTLLDGSKHRCLGVLLKFLDQEKL--HSDI--------LCKSINQLEVSVEVADRILYQLPTNDDIKTYRRYEYSDKLPINALTDEDRLLLTLCKVERLQQKLEVVVYIHNFPEAYKSLVEKVTFVTRASLAVRSSQKLKQILEIILAYGNLMNSSRRGIMYGFRLQSLDLLTDTKSLDKSWTLMQFFVDIVESKFQNLSDFSDEMRFVEQASKIPMEAITTDVASLVGGMKQVRDEMNCNTNQ--------PPRLKKFFEDNENLTADLSKSAANAKETFLQAAEWFGERQ-NNPTPDVFFGIFHRFTENFKKSLEDVRKRRAQSIILNIVPTEETPKAKPKDKKLALEARKKNRRMNNRTRQINADGIMDDILAGLDKTPLQAEIHPKRS 992
BLAST of Formin-like protein vs. Planmine SMEST
Match: SMESG000040024.1 (SMESG000040024.1) HSP 1 Score: 363.614 bits (932), Expect = 2.166e-107 Identity = 207/433 (47.81%), Postives = 285/433 (65.82%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPP--PQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGL---RSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDI 1300
MG+ S P+ K+ NS P NL+ FEKRW FIQSLDV P+N++ IDQL+ QK +LLLNFE+KNPK SAFHYVTLIK L +S + + +K+ D+ + +LSATE+SLRTN+V+WVYDFL ++GLE+L+DYMS+ L+ + + NY++ + N ++SD + S +F + + N I R +S V+K S +V +S+K LH LKC R ILNNQ+GC+MAF + I+VI +CL+HP+YQTK+L+L+ L+A+CLI G ++VL AF+ FK +T E +RFDTL+ ++R HET +DDYNID+ VS QFINI+VHS E+INLRVYLQ EFT+LGLD F +KL+ER GDRL +QV AY N VD ++LLED+E KE + + E+LE +
Sbjct: 1 MGSTSSKST-PQYKFINSGEGRLEMRPTNLQ-FEKRWDTFIQSLDVGPENVRQIDQLDPDQKEQLLLNFESKNPKYSAFHYVTLIKALQTGKSIRKSFNKKPDD--DPVHVLSATEVSLRTNNVDWVYDFLNNNGLEVLLDYMSKTLVLFL------------------NINYKNIETKKTLN-LQSDTKTHLSSS--DLFKSKKFNCCA---------SIKRRSSVVTKFQNSKDSVNESVKNSLHQGLKCMRAILNNQRGCEMAFVHSRAIDVIALCLLHPNYQTKTLVLETLAAICLIVNGLQKVLAAFEYFKEITGESRRFDTLITYFRDHETFKVDDYNIDFMVSCTQFINIVVHSGEDINLRVYLQQEFTILGLDDFYRKLEERSGDRLKKQVAAYNGNRVDVAILLEDSETKETVLLDYEKLEHEF 399 HSP 2 Score: 269.626 bits (688), Expect = 1.506e-74 Identity = 171/486 (35.19%), Postives = 259/486 (53.29%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGES---LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISE-NARRQMGDXXXXXXXXXXXXXXPKGD-------------QTRKK-----NRTRQINADGIMDEIMAGLDYQPLQAGLHARRG 3346
P+ W++L+NQQ GTVF ++ + +L+ + FE IFK+ P+ D+I ++ N S + + +K +LLD ++ +C+ +++ +L QEKL H I L +I +++ E ADR+LYQLP+ + YR +N L +EDRL+ L ++R++ KLE ++Y+ F E Y +L EK+ V A +V SQKLK+ILEI+LA+GN MN SRRG GFR+QSLD+L + +S D W+LM + +E KF +L +F E+ +VE AS++ + + L G+ +V +E++ N P RL F +N L AK F++ EWFGE+ +PD+FFG RF ++FKK++ + RR N +E +PK + RKK NRTRQINADGIMD+I+AGLD PLQA +H +R
Sbjct: 552 PVFNWSVLKNQQLKGTVFVSMNDEVLYDKLEFEKFENIFKLNPVG--------DSIPN---------GVDSNDSSEKTSKRKPEKKTLLDGSKHRCLGVLLKFLDQEKL--HSDI--------LCKSINQLEVSVEVADRILYQLPTNDDIKTYRRYEYSDKLPINALTDEDRLLLTLCKVERLQQKLEVVVYIHNFPEAYKSLVEKVTFVTRASLAVRSSQKLKQILEIILAYGNLMNSSRRGIMYGFRLQSLDLLTDTKSLDKSWTLMQFFVDIVESKFQNLSDFSDEMRFVEQASKIPMEAITTDVASLVGGMKQVRDEMNCNTNQ--------PPRLKKFFEDNENLTADLSKSAANAKETFLQAAEWFGERQ-NNPTPDVFFGIFHRFTENFKKSLEDVRKRRAQSIILNIVPTEETPKAKPKDKNLSMEELQKKLALEARKKNRRMNNRTRQINADGIMDDILAGLDKTPLQAEIHPKRS 1001
BLAST of Formin-like protein vs. Planmine SMEST
Match: SMESG000040024.1 (SMESG000040024.1) HSP 1 Score: 361.303 bits (926), Expect = 1.287e-106 Identity = 205/433 (47.34%), Postives = 280/433 (64.67%), Query Frame = 2
Query: 17 MGNQQQGSPYPRLKYSNSNNEAPP--PQNLEDFEKRWQVFIQSLDVTPQNIQNIDQLEAPQKIELLLNFEAKNPKCSAFHYVTLIKGL---RSYKMTNSKRKDEFQNAKQILSATEISLRTNHVEWVYDFLKHSGLEILVDYMSQILLHLIKSEEMQIFPITMNGTNTISSNYQSTGATISENGIESDFSPQANQSLRRIFDASQRNXXXXXXXXXXXXGINRNTXXXXXXXXXXXAVGDSIKECLHLCLKCFRTILNNQKGCQMAFEYKDTINVITMCLVHPSYQTKSXXXXXXSAVCLIEGGHERVLKAFDLFKVMTREEKRFDTLMYFYRHHETLPLDDYNIDYAVSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEAFIAECERLEKDI 1300
MG+ S P+ K+ NS P NL+ FEKRW FIQSLDV P+N++ IDQL+ QK +LLLNFE+KNPK SAFHYVTLIK L +S + + +K+ D+ + +LSATE+SLRTN+V+WVYDFL ++GLE+L+DYMS+ L+ +K + + T+ SS+ +F + + N I R +S V+K S +V +S+K LH LKC R ILNNQ+GC+MAF + I+VI +CL+HP+YQTK+L+L+ L+A+CLI G ++VL AF+ FK +T E +RFDTL+ ++R HET +DDYNID+ VS QFINI+VHS E+INLRVYLQ EFT+LGLD F +KL+ER GDRL +QV AY N VD ++LLED+E KE + + E+LE +
Sbjct: 1 MGSTSSKST-PQYKFINSGEGRLEMRPTNLQ-FEKRWDTFIQSLDVGPENVRQIDQLDPDQKEQLLLNFESKNPKYSAFHYVTLIKALQTGKSIRKSFNKKPDD--DPVHVLSATEVSLRTNNVDWVYDFLNNNGLEVLLDYMSKTLVLFLKQSDTK--------THLSSSD---------------------------LFKSKKFNCCA---------SIKRRSSVVTKFQNSKDSVNESVKNSLHQGLKCMRAILNNQRGCEMAFVHSRAIDVIALCLLHPNYQTKTLVLETLAAICLIVNGLQKVLAAFEYFKEITGESRRFDTLITYFRDHETFKVDDYNIDFMVSCTQFINIVVHSGEDINLRVYLQQEFTILGLDDFYRKLEERSGDRLKKQVAAYNGNRVDVAILLEDSETKETVLLDYEKLEHEF 385 HSP 2 Score: 269.626 bits (688), Expect = 1.091e-74 Identity = 171/486 (35.19%), Postives = 259/486 (53.29%), Query Frame = 2
Query: 1961 PLIKWNILRNQQ--GTVFEEIDGSQIEKQLDLDGFEKIFKVPPIEHEYDVPPLDTIDGKGLEIQRERNLNDNQLSGDGANDQSDKISLLDPNRQKCIKMVVTYLIQEKLLQHDSISFREWGRPLACAITNFDMASEAADRLLYQLPSFQETDMYRDITGES---LNVLANEDRLVALLSCIDRVEMKLEAILYMDAFDETYFALQEKIRTVALACRSVMESQKLKKILEIVLAFGNRMNDSRRGKAIGFRIQSLDMLPECRSPDDKWSLMNYIAFCIEEKFPDLKNFFSELEYVEDASRVSLCNLMAAFEELSTGLDRVAEELSLIKNAVENNPDLIPTRLVNFVRENITRVNLLRNQTEQAKIAFVKTVEWFGEKDLQTASPDLFFGALVRFMDSFKKAISE-NARRQMGDXXXXXXXXXXXXXXPKGD-------------QTRKK-----NRTRQINADGIMDEIMAGLDYQPLQAGLHARRG 3346
P+ W++L+NQQ GTVF ++ + +L+ + FE IFK+ P+ D+I ++ N S + + +K +LLD ++ +C+ +++ +L QEKL H I L +I +++ E ADR+LYQLP+ + YR +N L +EDRL+ L ++R++ KLE ++Y+ F E Y +L EK+ V A +V SQKLK+ILEI+LA+GN MN SRRG GFR+QSLD+L + +S D W+LM + +E KF +L +F E+ +VE AS++ + + L G+ +V +E++ N P RL F +N L AK F++ EWFGE+ +PD+FFG RF ++FKK++ + RR N +E +PK + RKK NRTRQINADGIMD+I+AGLD PLQA +H +R
Sbjct: 538 PVFNWSVLKNQQLKGTVFVSMNDEVLYDKLEFEKFENIFKLNPVG--------DSIPN---------GVDSNDSSEKTSKRKPEKKTLLDGSKHRCLGVLLKFLDQEKL--HSDI--------LCKSINQLEVSVEVADRILYQLPTNDDIKTYRRYEYSDKLPINALTDEDRLLLTLCKVERLQQKLEVVVYIHNFPEAYKSLVEKVTFVTRASLAVRSSQKLKQILEIILAYGNLMNSSRRGIMYGFRLQSLDLLTDTKSLDKSWTLMQFFVDIVESKFQNLSDFSDEMRFVEQASKIPMEAITTDVASLVGGMKQVRDEMNCNTNQ--------PPRLKKFFEDNENLTADLSKSAANAKETFLQAAEWFGERQ-NNPTPDVFFGIFHRFTENFKKSLEDVRKRRAQSIILNIVPTEETPKAKPKDKNLSMEELQKKLALEARKKNRRMNNRTRQINADGIMDDILAGLDKTPLQAEIHPKRS 987
BLAST of Formin-like protein vs. Planmine SMEST
Match: SMESG000040019.1 (SMESG000040019.1) HSP 1 Score: 79.337 bits (194), Expect = 1.875e-16 Identity = 40/73 (54.79%), Postives = 51/73 (69.86%), Query Frame = 2
Query: 1046 VSNMQFINIIVHSVENINLRVYLQYEFTLLGLDSFLKKLQERPGDRLNRQVDAYLDNLVDCSVLLEDAEAKEA 1264
VS QFIN + H ++IN+RVY+Q EF +LGLD F KL+ER GDRLN+QV AY + V +L+ED E KE
Sbjct: 39 VSFAQFINNVTHFGDDINIRVYIQQEFNILGLDDFYIKLEERSGDRLNKQVVAYNGHRVYVIILIEDLETKET 111 The following BLAST results are available for this feature:
BLAST of Formin-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Formin-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Formin-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Formin-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Formin-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Formin-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014928 ID=SMED30014928|Name=Formin-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3841bpback to top protein sequence of SMED30014928-orf-1 >SMED30014928-orf-1 ID=SMED30014928-orf-1|Name=SMED30014928-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1129bp MAMGNQQQGSPYPRLKYSNSNNEAPPPQNLEDFEKRWQVFIQSLDVTPQNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
