ATP-dependent DNA helicase DDX11

Query:  451 ESNEENFVV-NYNSDEE--VSNDIENQENEGS---ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKP-IGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQM-----------DSEKATDELGNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMK-VMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYG-----SESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            ES EE  V+  Y SDEE  V++ ++  E++     ITKIYYCSRTHSQL Q + E+ K+ +   +     GSRQNLC+N  V  L S+ LIN++C+D+Q+    K     E   K+R+    A C F ++E++  +    +    D+EQL+  G ++  CP+YG + +   A LV++PYQ +L+ A R A+ I ++D +VI DEAHNL DTI+ ++SV++  S L     QL  Y+ +Y +R  +KNL+YL+Q+  +    +  +   I    +  SLS          +FLF++ ++ + L ++  + +KS ++ KL             V   R+   L G  Q ++  Q            +S+ +T    + ++ ++ F+AA+  +  D  +++ +   L+     FL+++P  +   +V +CR++++ GGTMQP SDF  +L   A   ++R+  FSC HVI     +  V+  G++  N PL FTF+ R    M+   G I  ++    P GVV FF SY  + ++   W+  G+L  +   K ++ EPK + Q E V+  +++          ++          GA+L +V+G KMSEGINFSD L R V++VG+P+P  RS  LQEKM+Y+++        +   + +  NL MK VNQ+IGRAIRH+ DFA+++LLD+RYA    +++         LP+W++  V ++      I+ ++ F +
Sbjct:  165 ESGEEELVLAEYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGA----VFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMHIQGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGIS--NQPLEFTFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSR---------CIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFASVVLLDQRYARPPVLAK---------LPAWIRARVEVKATFGPAIAAVQKFHR 874          

Query:   88 MSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
            M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL
Sbjct:    1 MAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWL 36          

Query:  451 ESNEENFVV-NYNSDEE--VSNDIENQENEGS---ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKP-IGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQM-----------DSEKATDELGNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMK-VMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYG-----SESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSF 2523
            ES EE  V+  Y SDEE  V++ ++  E++     ITKIYYCSRTHSQL Q + E+ K+ +   +     GSRQNLC+N  V  L S+ LIN++C+D+Q+    K     E   K+R+    A C F ++E++  +    +    D+EQL+  G ++  CP+YG + +   A LV++PYQ +L+ A R A+ I ++D +VI DEAHNL DTI+ ++SV++  S L     QL  Y+ +Y +R  +KNL+YL+Q+  +    +  +   I    +  SLS          +FLF++ ++ + L ++  + +KS ++ KL             V   R+   L G  Q ++  Q            +S+ +T    + ++ ++ F+AA+  +  D  +++ +   L+     FL+++P  +   +V +CR++++ GGTMQP SDF  +L   A   ++R+  FSC HVI     +  V+  G++  N PL FTF+ R    M+   G I  ++    P GVV FF SY  + ++   W+  G+L  +   K ++ EPK + Q E V+  +++          ++          GA+L +V+G KMSEGINFSD L R V++VG+P+P  RS  LQEKM+Y+++        +   + +  NL MK VNQ+IGRAIRH+ DFA+++LLD+RYA    +++         LP+W++  V ++      I+ ++ F
Sbjct:  191 ESGEEELVLAEYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGA----VFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMHIQGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGIS--NQPLEFTFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSR---------CIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFASVVLLDQRYARPPVLAK---------LPAWIRARVEVKATFGPAIAAVQKF 898          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
            F FP+ PY  Q   M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL
Sbjct:   13 FPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWL 62          

Query:  451 ESNEENFVV-NYNSDEE--VSNDIENQENEGS---ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPI-GKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQM-----------DSEKATDELGNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMK-VMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYG-----SESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSF 2523
            ES EE  V+  Y SDEE  V++ ++  E++     ITKIYYCSRTHSQL Q + E+ K+ +   +     GSRQNLC+N  V  L S+ LIN++C+D+Q+    K     E   K+R+    A C F ++E++  +    +    D+EQL+  G ++  CP+YG + +   A LV++PYQ +L+ A R A+ I ++D +VI DEAHNL DTI+ ++SV++  S L     QL  Y+ +Y +R  +KNL+YL+Q+  +    +  +   I    +  SLS          +FLF++ ++ + L ++  + +KS ++ KL             V   R+   L G  Q ++  Q            +S+ +T    + ++ ++ F+AA+  +  D  +++ +   L+     FL+++P  +   +V +CR++++ GGTMQP SDF  +L   A   ++R+  FSC HVI     +  V+  G++  N PL FTF+ R    MI                                                  + EPK + Q E V+  +++          ++          GA+L +V+G KMSEGINFSD L R V++VG+P+P  RS  LQEKM+Y+++        +   + +  NL MK VNQ+IGRAIRH+ DFA+++LLD+RYA    +++         LP+W++  V ++      I+ ++ F
Sbjct:  191 ESGEEELVLAEYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGA----VFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMHIQGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGIS--NQPLEFTFQKRELPQMI--------------------------------------------------FQEPKSAHQVEQVLLAYSR---------CIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFASVVLLDQRYARPPVLAK---------LPAWIRARVEVKATFGPAIAAVQKF 848          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
            F FP+ PY  Q   M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL
Sbjct:   13 FPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWL 62          

Query:  451 ESNEENFVV-NYNSDEE--VSNDIENQENEGS---ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKP-IGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQM-----------DSEKATDELGNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMK-VMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKI 2415
            ES EE  V+  Y SDEE  V++ ++  E++     ITKIYYCSRTHSQL Q + E+ K+ +   +     GSRQNLC+N  V  L S+ LIN++C+D+Q+    K     E   K+R+    A C F ++E++  +    +    D+EQL+  G ++  CP+YG + +   A LV++PYQ +L+ A R A+ I ++D +VI DEAHNL DTI+ ++SV++  S L     QL  Y+ +Y +R  +KNL+YL+Q+  +    +  +   I    +  SLS          +FLF++ ++ + L ++  + +KS ++ KL             V   R+   L G  Q ++  Q            +S+ +T    + ++ ++ F+AA+  +  D  +++ +   L+     FL+++P  +   +V +CR++++ GGTMQP SDF  +L   A   ++R+  FSC HVI     +  V+  G++  N PL FTF+ R    M+   G I  ++    P GVV FF SY  + ++   W+  G+L  +   K ++ EPK + Q E V+  +++          ++          GA+L +V+G KMSEGINFSD L R V++VG+P+P  RS  LQEKM+Y++ Q  S            +PV++  GR   H+    A     +R A    I
Sbjct:  191 ESGEEELVLAEYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVEVSGSQLCQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGA----VFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASTLRPASPLMHIQGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGIS--NQPLEFTFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSR---------CIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLD-QTLSPRPGTPREGSGGEPVHE--GRQPVHRQGHQAPEGFCQRSAPGPAI 863          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
            F FP+ PY  Q   M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL
Sbjct:   13 FPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWL 62          

Query: 1570 LTFLVVDPGKYLKDIVNQ-CRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSC---EHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQ-NENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSE-------SSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            L++    PG  + ++V Q  RS+I+  GT+ P S F+  +         +I    C    H+I+ K Q+ V  +        L   F+ R +E  + + G    +I    P G++IFF SY VM+K +E W+++ +  +++ LK +++EP+     +E + A + +                +A  + GA   AV   K SEG++FSD   R VI+ G+PYP    P +  KM ++++  G         S +  Y   A + VNQAIGR IRH+ D+ A+ L D R+A             +  LPSW++  V + +N   +I ++  FF+
Sbjct:  453 LSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEM---------QIPFPVCLENPHIID-KHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYAR---------------VAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFA---------FADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFR 750          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVS--KNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGL 1116
            I KI Y SRTHSQL QV+ EL  TSY  K+  C  GSR+ LCI+  V + +S +L    C                    RK      C F  Y  +EE S  + +    +DIE LV +G K   CP+Y  +    +A ++ MPY  +L+  +R A  I++K  +VIFDEAHN+     +  S  L    L +GL
Sbjct:  106 IPKIIYASRTHSQLTQVINELRNTSYRPKV--CVLGSREQLCIHPEVKKQESNHLQIHLC--------------------RKKVASRSCHF--YNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGL 276          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDF 282
            +FP++PY  Q + M+++   ++++  GI ESPTGTGK+L +LC++L W          E +++ +  ++I + +Q + 
Sbjct:   12 DFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAW---------REHLRDGISARKIAERAQGEL 80          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEI--KQIEDDSQNDFD-WINAYAQSKKSK---LNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVS--------NDIENQENEG-SITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGAC---CSFKSYEKIEEVSKNIIRHPM-DIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLI------KENQMDSEKATDELGNAMLTVRNFIAAVYYSL-DASILVEK---DVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            F+FP++PY  Q+ LM E+   IE+RKIGIFESPTGTGKSLSVLCS++ WL   +     +L     E+  K  E D     D W  A  +  +++     + +Q +  E+ +  +DQ +   ++         +D +   +  +E      YN+DE+          +D++ +E +     KI+Y SRTHSQL Q+ +EL KT +  +I TC   SR  LC+N  V +LK  +LINEKC++L+K      +  + L K     T  C   C F +  +IE+V   ++ + +    ++   G  S GCP++  +KS  +  LVL+PYQ +L+   R A  IE+KDN+++ DEAHN+ +TIS + S ++    L   L+ ++ Y   Y  +  + NLLY++QLE++ S ++ F++ +      ++  +      + E+ L ++  +++K+ L  K       ++  ++      +   L G  +L+       E + +       + + + ++++FI A+     D  I+VEK   +    F++++P   L ++V   R+ I++GGTM+P       L + +   +D I  FSC HVI+  Q + V T+       P + T++ R  +  +++      ++    PNGVVIF  SY+ +    ++ +  G+L  I++ K+V+ E +Q   +                  +   F+ +AK++KGA+LFAV+G KMSEGINF DEL R VI++G+PYP   S  L+E+M +++ Q  +    ++Y +L M  VNQAIGRAIRH+ D+AA+ L D+RYA      E+  RK    L +W+ D   ++     +I + +SFF+
Sbjct:    4 FSFPFQPYDIQLNLMREIRQCIEQRKIGIFESPTGTGKSLSVLCSTMTWLEAEELRISTDLSTRLGEVHTKITECDKITTADNWETAVREKMRAQDVETEILEQIQSRERLQSRIDQARRGMVEVSRKRKAPARDTDQFLEPQDEAAPSEEYNNDEKSEKQRDSDFFDDVDEEEEKPLKCLKIFYASRTHSQLEQLAEELAKTRFQPRIVTC--ASRGTLCVNEEVKKLKLNHLINEKCMELRKNGMSEKEKVQKLEKGTTKKTKTCATSCEFYNSTQIEDVVNGVLSNKLKSTLEVSKQGKLSNGCPYFATRKSVPQCQLVLLPYQVLLHDGTRKAWGIELKDNVIVLDEAHNVLNTISSLYSAEISTKSLTLALRLIREYNAHYKLKLLAHNLLYMKQLESLTSKMLIFLNSQ-SKEDVMTMAQLARNLNILEINLFKLAEYMEKTDLCKKFHGFYMRLQKEEIKKE--NEKPKLTGIQKLMAAKEAEPEPEAEPLPPPKPVPSPLFSLKSFIDALTNKCEDGRIIVEKSATEAKFRFMLLNPADRLSEVVTSARATILVGGTMEPAQLLVETLSRGS-IGADSIRRFSCCHVIDDSQLLAV-TVERTVDGKPFQLTYQTRGADTTLRSLATSIQALIPHIPNGVVIFVPSYDFLFNFQKKMKEFGILKRIEEKKAVFTESRQPTSD------------------VWDRFSRAAKTSKGAILFAVVGGKMSEGINFCDELGRAVIVIGLPYPNKTSVELRERMKFLDTQMPN-GGNLLYESLCMHAVNQAIGRAIRHRRDYAAVYLFDDRYA-----KESTRRK----LSTWIGDRTQVKLGFGEIIRKTRSFFE 825          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEI--KQIEDDSQNDFD-WINAYAQSKKSK---LNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVS--------NDIENQENEG-SITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGAC---CSFKSYEKIEEVSKNIIRHPM-DIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLI------KENQMDSEKATDELGNAMLTVRNFIAAVYYSL-DASILVEK---DVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            F+FP++PY  Q+ LM E+   IE+RKIGIFESPTGTGKSLSVLCS++ WL   +     +L     E+  K  E D     D W  A  +  +++     + +Q +  E+ +  +DQ +   ++         +D +   +  +E      YN+DE+          +D++ +E +     KI+Y SRTHSQL Q+ +EL KT +  +I TC   SR  LC+N  V +LK  +LINEKC++L+K      +  + L K     T  C   C F +  +IE+V   ++ + +    ++   G  S GCP++  +KS  +  LVL+PYQ +L+   R A  IE+KDN+++ DEAHN+ +TIS + S ++    L   L+ ++ Y   Y  +  + NLLY++QLE++ S ++ F++ +      ++  +      + E+ L ++  +++K+ L  K       ++  ++      +   L G  +L+       E + +       + + + ++++FI A+     D  I+VEK   +    F++++P   L ++V   R+ I++GGTM+P       L + +   +D I  FSC HVI+  Q + V T+       P + T++ R  +  +++      ++    PNGVVIF  SY+ +    ++ +  G+L  I++ K+V+ E +Q   +                  +   F+ +AK++KGA+LFAV+G KMSEGINF DEL R VI++G+PYP   S  L+E+M +++ Q  +    ++Y +L M  VNQAIGRAIRH+ D+AA+ L D+RYA      E+  RK    L +W+ D   ++     +I + +SFF+
Sbjct:    4 FSFPFQPYDIQLNLMREIRQCIEQRKIGIFESPTGTGKSLSVLCSTMTWLEAEELRISTDLSTRLGEVHTKITECDKITTADNWETAVREKMRAQDVETEILEQIQSRERLQSRIDQARRGMVEVSRKRKAPARDTDQFLEPQDEAAPSEEYNNDEKSEKQRDSDFFDDVDEEEEKPLKCLKIFYASRTHSQLEQLAEELAKTRFQPRIVTC--ASRGTLCVNEEVKKLKLNHLINEKCMELRKNGMSEKEKVQKLEKGTTKKTKTCATSCEFYNSTQIEDVVNGVLSNKLKSTLEVSKQGKLSNGCPYFATRKSVPQCQLVLLPYQVLLHDGTRKAWGIELKDNVIVLDEAHNVLNTISSLYSAEISTKSLTLALRLIREYNAHYKLKLLAHNLLYMKQLESLTSKMLIFLNSQ-SKEDVMTMAQLARNLNILEINLFKLAEYMEKTDLCKKFHGFYMRLQKEEIKKE--NEKPKLTGIQKLMAAKEAEPEPEAEPLPPPKPVPSPLFSLKSFIDALTNKCEDGRIIVEKSATEAKFRFMLLNPADRLSEVVTSARATILVGGTMEPAQLLVETLSRGS-IGADSIRRFSCCHVIDDSQLLAV-TVERTVDGKPFQLTYQTRGADTTLRSLATSIQALIPHIPNGVVIFVPSYDFLFNFQKKMKEFGILKRIEEKKAVFTESRQPTSD------------------VWDRFSRAAKTSKGAILFAVVGGKMSEGINFCDELGRAVIVIGLPYPNKTSVELRERMKFLDTQMPN-GGNLLYESLCMHAVNQAIGRAIRHRRDYAAVYLFDDRYA-----KESTRRK----LSTWIGDRTQVKLGFGEIIRKTRSFFE 825          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEK--IEEVSKNIIR-HPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQ--------------LIKENQMDSEKATDELGNAMLTVRNFIAAVY--YSLDASILVEKDVGLTFLVVDPGKYLKDIVNQC----------------------------------RSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMT-LGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQS--------KGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYG-------SESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            +  I+Y SRTHSQL QV+ EL +T Y   + T   GSR++ CIN  V ++K  N     C  L                   V+  AC  +  ++    +++++ + +   MDIE  V  G ++  CP++  ++    A L+L+PY  +++P  R   K+++K++IVIFDEAHNL        S +L  + +   +++LK  +   +    +       +     S  I+   + I++  +   +  L K +  E ++D++      S+L      S +     D  ++    + A F  N               L+ +N+   E A  E G+ M  V +F+ ++Y  ++ D +  V ++       VDP    K +   C                                  R++++  GT+ P   F+  +  N             EH +   +Q+ V+T +    K   L  +F+NR N   +    +  L +    P G++IFFSSY+ MD+++  W++        +    +++K K V +EP+     E + AI         RL     +T       GA L AV   K+SEGI+F D  +R VII+GIPYP      +  K  Y++   G        +SS+  Y   A + VNQAIGR +RHK+DF  ++L+D RYA     ++ E+       P WL++++S +++T+    +   FF+
Sbjct:  102 VPTIFYASRTHSQLEQVVHELNRTEYK-WVKTTILGSREHFCINQKVKKIKESNRQAHVCRGL-------------------VSKRACHYYNKFDACTTDKMTEFLDKGEAMDIEDFVKLGTQNSLCPYFMSRQRSETAELILLPYNYIIDPKMRRRYKLDLKNSIVIFDEAHNLESICESNASAELTSTSIALCIEELKKVLALLVDEEETARSEADAETGAFGSAKIDLTKKLIENLRTEDLMTVLEKIFSLEEEMDKLFG---SSQLKSVPPLSGK---ASDGEILLETLAKAGFDANSVERLVDVLRDAISYLLSKNE---EVALTEKGDGMEKVADFLLSIYSTHAQDVAAAVGEETVKLVDRVDP----KTVARNCKLYIQKDKDNEKLTIKYFCFQASISMRMLKMRGVRNVLLASGTLSPIQAFTYNMGLNFGA------ILENEHAL---KQVPVLTSIVTRGKRGGLAGSFQNRKNLDYVTGVAEALLRVMEVIPQGILIFFSSYSQMDELVATWKTTKWSSNSNESFWEKMEKTKRVVVEPRA---KEELAAI---------RL----RYTQGVSEQHGAALLAVCRGKVSEGIDFCDAESRAVIIIGIPYPPIHDERVVLKKMYLDDLMGRKDTKSERQSSQDWYQMEAFRAVNQAIGRVLRHKDDFGTVVLMDTRYAS----AKPEM------FPKWLRNTIS-RSDTDGCALKTSRFFK 765          

Query:   31 NQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQ 216
            N   +  FP+EPY  Q   M  +   ++++     ESPTGTGK+LS+LCS+L W+   +E +
Sbjct:   14 NPKLSVKFPFEPYECQRIFMKNVVDVLDRKLDAALESPTGTGKTLSLLCSTLAWVQRQKETK 75          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEK--IEEVSKNIIR-HPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQ--------------LIKENQMDSEKATDELGNAMLTVRNFIAAVY--YSLDASILVEKDVGLTFLVVDPGKYLKDIVNQC----------------------------------RSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMT-LGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQS--------KGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYG-------SESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            +  I+Y SRTHSQL QV+ EL +T Y   + T   GSR++ CIN  V ++K  N     C  L                   V+  AC  +  ++    +++++ + +   MDIE  V  G ++  CP++  ++    A L+L+PY  +++P  R   K+++K++IVIFDEAHNL        S +L  + +   +++LK  +   +    +       +     S  I+   + I++  +   +  L K +  E ++D++      S+L      S +     D  ++    + A F  N               L+ +N+   E A  E G+ M  V +F+ ++Y  ++ D +  V ++       VDP    K +   C                                  R++++  GT+ P   F+  +  N             EH +   +Q+ V+T +    K   L  +F+NR N   +    +  L +    P G++IFFSSY+ MD+++  W++        +    +++K K V +EP+     E + AI         RL     +T       GA L AV   K+SEGI+F D  +R VII+GIPYP      +  K  Y++   G        +SS+  Y   A + VNQAIGR +RHK+DF  ++L+D RYA     ++ E+       P WL++++S +++T+    +   FF+
Sbjct:  102 VPTIFYASRTHSQLEQVVHELNRTEYK-WVKTTILGSREHFCINQKVKKIKESNRQAHVCRGL-------------------VSKRACHYYNKFDACTTDKMTEFLDKGEAMDIEDFVKLGTQNSLCPYFMSRQRSETAELILLPYNYIIDPKMRRRYKLDLKNSIVIFDEAHNLESICESNASAELTSTSIALCIEELKKVLALLVDEEETARSEADAETGAFGSAKIDLTKKLIENLRTEDLMTVLEKIFSLEEEMDKLFG---SSQLKSVPPLSGK---ASDGEILLETLAKAGFDANSVERLVDVLRDAISYLLSKNE---EVALTEKGDGMEKVADFLLSIYSTHAQDVAAAVGEETVKLVDRVDP----KTVARNCKLYIQKDKDNEKLTIKYFCFQASISMRMLKMRGVRNVLLASGTLSPIQAFTYNMGLNFGA------ILENEHAL---KQVPVLTSIVTRGKRGGLAGSFQNRKNLDYVTGVAEALLRVMEVIPQGILIFFSSYSQMDELVATWKTTKWSSNSNESFWEKMEKTKRVVVEPRA---KEELAAI---------RL----RYTQGVSEQHGAALLAVCRGKVSEGIDFCDAESRAVIIIGIPYPPIHDERVVLKKMYLDDLMGRKDTKSERQSSQDWYQMEAFRAVNQAIGRVLRHKDDFGTVVLMDTRYAS----AKPEM------FPKWLRNTIS-RSDTDGCALKTSRFFK 765          

Query:   31 NQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQ 216
            N   +  FP+EPY  Q   M  +   ++++     ESPTGTGK+LS+LCS+L W+   +E +
Sbjct:   14 NPKLSVKFPFEPYECQRIFMKNVVDVLDRKLDAALESPTGTGKTLSLLCSTLAWVQRQKETK 75          

Query: 1528 YSLDASILVEKDVGLTFLVV-----DPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKD 2469
            YS   S++VE   G    V+     D    ++ ++++ +S+I+  GT+ P   +   L  +   PS  I +F+   +  A+  +  + +   +  V +   FE R + A+I+  G++ L + S  P+G+V+FF+SY  M+ +I  W  + ++ E+ K K ++IE   +L+                    +  +  +  S +GAVLF+V   K+SEGI+FS  L R VI++GIPY  T S +L+ ++ Y+  Q+G + +  +  + AM+   Q +GRA+R K D+  ++  D+R+      S N+ ++GK  LP W+++
Sbjct:  408 YSKGFSVIVEPQDGSQLAVITLSCHDASIAIRPVMSRFQSVIITSGTLSPLEMYPKVLDFD---PS-VIASFT---MTLARPCLSPLVVARGNDQVAMTSRFEQRADVAVIRNYGNLVLEMASLVPDGMVVFFTSYLYMENVIGVWYEQHIIDELMKYKLLFIETNDALETSAA----------------LEKYVEACDSGRGAVLFSVARGKVSEGIDFSHHLGRCVIMLGIPYMYTESRVLRARLEYLRDQFGIKENDFLTFD-AMRHTAQCMGRALRSKTDYGLMVFADKRF------SRND-KRGK--LPRWMQE 693          

Query:  538 ITKIYYCSRTHSQLNQVLQEL-LKTSYADK-----IA--TCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKV---TTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSR 1230
            + K+ YCSRT  ++ + ++E+ +   Y +K     +A  T    +R+NLC+N  V  L+  N ++  C           ++T + A++++    T  AC  F+++E      +N +    ++E L   G +   CP++  +++ N+AH+V+  Y  +L+P  A L SK   + ++V+FDEAHN+ +   +  SV +   +    L++L+S +   + R  S N     +L++ +  L+E + R
Sbjct:   67 LDKLVYCSRTIPEIEKCVEEMKVLYDYWEKETGQPVAKITVAMSARKNLCVNEPVAALRFGNTVDSAC----------QKLTASSARQKRAEDPTLEACDYFENFEAKSVPMQNGV---WNLEDLRSLGREKKICPYFTARQAINRAHIVVYSYHYILDPKIAELVSKDFSRKSVVVFDEAHNIDNVCIESMSVAISQKNADRALQELQS-LEGVVNRMKSSN---SEKLQSEYDKLVEGLKR 292          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKN----KLEIKQIEDDSQNDFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEE---VSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGA--CCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKID----SYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSA-----------LFGGNQLIKE---------NQMDSEKATDELGNAMLTVRNFIAAVYYSL----------------DASILVEKDVG-LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAK--SNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNS 2499
            F FPY PY  Q +LM EL+  +E+ ++GIFESPTGTGKSL++ C +L WL  ++E    E++      + E+ +++++S+   +W+ +  +S+  +  L               Q+  I+   +   +      +    E  E++     +SD E        E  E+     +I++CSRTHSQL Q++ EL KT +   + +   GSRQ LC N  V +LK + L+NE+CLD+      T +     +KK ++T  A   C FK+   +E +    +  P+DIE+L   G   GGC +Y  + +   A L+L+PYQ +L  +AR    I +K +IVI DEAHNL D+++ ++  ++    L     Q+  Y   + +RF++KNLL + Q+  I   L++ + ++ +      S +   E   +     + L  +L+F  +++ A K++     +E       RP ++ A                Q +KE           ++ E   +EL       +  +  V  S                 D  ILV+   G L ++++DP +   DIV + R++++ GGTMQP  +   +LF       DR+      HV+ A   +    +       PL F F +R +  M++    I  ++    P GVV F  SY  +DK+ +  +  G L  I   KSV+ E   S +                   ++ N+  + K  ++ GA+L +V+G K+SEG+NF+D+L R V++VG+PY  + SP L+++M +++++ G  +    Y NL +K VNQ IGRA+RH  D+A + LLD+R+AD  KI      +GK  LP W+   +   N  N 
Sbjct:   18 FGFPYSPYEIQEQLMQELFQVLERGQVGIFESPTGTGKSLTLTCGALTWLARHEELVRTEMLARIRGVEQELAKLKEESEQSSNWLESQGKSRAQRAELLRLQHLQALLDKQEQQLDQIRKGAK--KHKRQGRVHPGKLEELEKDLDPESDSDSEHETADGPQEAAEDRYRPVQIFFCSRTHSQLAQIVAELRKTPHGQSVRSISLGSRQQLCGNPAVRKLKHVGLMNERCLDM-----ATKKARPNPSKKSRLTAEANSRCPFKAASLVESLRDLALTEPLDIEELANEGTACGGCSYYASRSAVEHAQLILLPYQLLLQKSARNQLGISLKGSIVIVDEAHNLLDSVAQLHGSEISRQQLERAKVQISGYKDHFQKRFTTKNLLKINQIIFIIRRLLKILDQRKELQSNGCSMMRTYELTAEGDFFNIDLCELLDFCARTRFARKVQGRADRMEREP----RPSENQAPVSTARSLILQRLASEQKLKEKTKSVKRRVEDINKEDKAEELQEQQKPTKKPVEEVAPSPIRPLLAFLETLTSNAEDGRILVDPVGGTLKYILLDPAEQFADIVAEARAIVIAGGTMQPTKELKEQLFTGCH---DRLVERFYNHVV-ANDAILPFVISNGPSGAPLSFKFAHRGSAEMLRELSMILRNLCQVVPGGVVCFLPSYEYLDKVYKYLEQSGTLETISGRKSVFREVSGSAEQ------------------LLDNYALAIKRPASYGALLLSVVGGKLSEGLNFADDLGRAVLVVGLPYSNSLSPELRQRMQHLDEKLGPGAGNEYYENLCVKAVNQCIGRAVRHIKDYACVYLLDKRFAD-PKI------RGK--LPKWISRHIVEANAANG 845          

Query: 1570 LTFLVVDPGKYLKDIVN-QCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIM---YHNL-AMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTN---SLISELKSFFQ 2529
            + F   +PG  ++ ++N Q RS+I+  GT+ P           AE            H+++ + Q+ V  +G       L   + NR+N   I + G   L++    P+G+++FF SY +++K ++ WQ+ G+ ++I   K +++EP+   Q       FT           M  F  + + +KGAV  AV   K+SEG++F+D   R VII G+P+P  + P +  K  Y+E     E+  +    ++NL A + VNQAIGR IRH+ND+ AI+L D R+ D +++ +         L  W++  +  +   +    ++ EL+ FF+
Sbjct:  454 INFWCFNPGFGMEQLLNTQVRSVILTSGTLAPLKPLI------AELAIPVAQHLENPHIVD-QSQVYVKIIGTGPDRQQLISNYANRDNPKYISSLGQTILNVARIVPDGLLVFFPSYPMLNKCVDAWQASGLWADISCKKPIFLEPRSKDQ-------FTS---------TMEEFYQAIRDSKGAVFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLEANRTRENQLLSGQEWYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRFKDASQVQQ---------LSKWIRGHLGDRPQCSPFGPIVRELRQFFK 749          

Query:  517 NQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNI--IRHP--MDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSS 1164
             + N   + K+ Y SRTHSQL Q ++EL +T+YA+ + +   GSR  LCI+  V + +  +     C                   K +V +  C    S++   E  K+   +R P  MDIE LV  G +   CP++  ++   +A +  MPY  +L+P AR A+KIE+ + IVI DEAHN+     +  SV++  S +   ++     +   +Q F+S
Sbjct:   99 GRANNWGVPKVIYASRTHSQLTQAMRELKRTAYAN-MRSVVLGSRDQLCIHPEVMREQGNSNKTNMC-------------------KLRVHSKTC----SFQMRVESRKDHPDLRGPTIMDIEDLVKVGQRLKICPYFASRELVPQADITFMPYNYLLDPKARKANKIELGNTIVILDEAHNIEKICEESASVQIKSSDVAMAIED----VTHIMQVFAS 290          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIK 234
            +FP+EPYP Q   M ++   +     G+ ESPTGTGK+LS+LCSSL W+   Q     +++K
Sbjct:   12 HFPFEPYPVQRAYMEKVIHCLRDGTNGVLESPTGTGKTLSLLCSSLAWIRTRQSEHQKQMVK 73          

Query: 1570 LTFLVVDPGKYLKDIVN-QCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIM---YHNL-AMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTN---SLISELKSFFQ 2529
            + F   +PG  ++ ++N Q RS+I+  GT+ P           AE            H+++ + Q+ V  +G       L   + NR+N   I + G   L++    P+G+++FF SY +++K ++ WQ+ G+ ++I   K +++EP+   Q       FT           M  F  + + +KGAV  AV   K+SEG++F+D   R VII G+P+P  + P +  K  Y+E     E+  +    ++NL A + VNQAIGR IRH+ND+ AI+L D R+ D +++ +         L  W++  +  +   +    ++ EL+ FF+
Sbjct:  454 INFWCFNPGFGMEQLLNTQVRSVILTSGTLAPLKPLI------AELAIPVAQHLENPHIVD-QSQVYVKIIGTGPDRQQLISNYANRDNPKYISSLGQTILNVARIVPDGLLVFFPSYPMLNKCVDAWQASGLWADISCKKPIFLEPRSKDQ-------FTS---------TMEEFYQAIRDSKGAVFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLEANRTRENQLLSGQEWYNLDATRAVNQAIGRVIRHRNDYGAILLCDSRFKDASQVQQ---------LSKWIRGHLGDRPQCSPFGPIVRELRQFFK 749          

Query:  517 NQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNI--IRHP--MDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSS 1164
             + N   + K+ Y SRTHSQL Q ++EL +T+YA+ + +   GSR  LCI+  V + +  +     C                   K +V +  C    S++   E  K+   +R P  MDIE LV  G +   CP++  ++   +A +  MPY  +L+P AR A+KIE+ + IVI DEAHN+     +  SV++  S +   ++     +   +Q F+S
Sbjct:   99 GRANNWGVPKVIYASRTHSQLTQAMRELKRTAYAN-MRSVVLGSRDQLCIHPEVMREQGNSNKTNMC-------------------KLRVHSKTC----SFQMRVESRKDHPDLRGPTIMDIEDLVKVGQRLKICPYFASRELVPQADITFMPYNYLLDPKARKANKIELGNTIVILDEAHNIEKICEESASVQIKSSDVAMAIED----VTHIMQVFAS 290          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIK 234
            +FP+EPYP Q   M ++   +     G+ ESPTGTGK+LS+LCSSL W+   Q     +++K
Sbjct:   12 HFPFEPYPVQRAYMEKVIHCLRDGTNGVLESPTGTGKTLSLLCSSLAWIRTRQSEHQKQMVK 73          

Query: 1570 LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSV 2475
            L F  +D    +  + ++ +++++  GT+ P   +   L  +    S    T        A+  +  M +   +  V +   FE R + A+I+  G + + +    P+G+V FF+SY  ++ ++  W  +G++  + + K ++IE + + +    +                 N+  +    +GAVL AV   K+SEG++F     R V++ GIPY  T+S IL+ ++ Y+  Q+    +  +  + AM+   Q +GRA+R K D+  +I  D+R++   K S          LP W+++ +
Sbjct:  433 LHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTL-------ARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAETSYALM----------------NYVKACDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRENDFLTFD-AMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSR---------LPKWIQEHL 701          

Query:  523 ENEGSITKIYYCSRTHSQLNQVLQEL--LKTSY------ADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRK---VTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKL 1089
            E+  ++ K+ YCSRT  ++ +V+ EL  L   Y                SR+N+CI+  V++ +    ++ KC  L          T +  ++R      T  C  F+ +  +E     +      I+ L   G     CP++  + +   AH+V+  Y  +L+P  A++ SK   +++ V+FDEAHN+ +   D  SVK+
Sbjct:   62 EHPETVRKLIYCSRTVPEIEKVIAELQNLMVYYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGL----------TASYIRERHEMDTETPICQYFEGF-SLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMSVKI 251          

Query:   25 MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNE---LIKNKLEIKQIEDDSQN----DFDWINAYAQSKK-----SKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVV-NYNSDEEVS---------NDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQK-PIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI-DSYSSLSCV---------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRP------RQSSALFGGNQLIKENQMD---SEKATDE---LGNAMLTVRNFIAAVYYS-LDASILVEKDV-----GLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
            M ++   F FP++PYP Q   M  LY  +++RK+GIFESPTGTGKSLS++C +L WL   +E +  E   L++ + +   +++ + N    + DW++ + Q K      +KL   + +E                     +   + +          EE  +V  Y SD+E +         ND ++   E  +TKIYYCSRTHSQL Q + E+ K+ Y D +     GSRQNLCIN  V +L ++ ++NE+CL++QK    K  + +++ +K+ +    A C F  +E +  +   ++    D+EQL+  G ++  CP+Y  + S   A +V++PYQ++L+ + R AS I++KD IVI DEAHNL DTIS ++S ++    L     QL  Y  +Y  R  +KNL+Y++Q+  +   L+  +  K+  + ++ SC          +FLFK  ++ + L ++  + +KS ++ KL       E   +           R++  L    Q ++    D    + A ++   + + M+   +F+ A+  +  D  +++++        L FL+++   +   I+ +CR++I+ GGTMQP +DF  +L  +A    +RI  FSC HVI  +  + ++ L        L FTF+ R++  M++ TG +  ++ +  P GVV FF SY    +I+  W+S G+L  ++  K ++ EPK++ Q E V++ ++K          ++  +       GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  +SP LQEKM+Y++K      G    + +  +L MK VNQ+IGRAIRH+ D+A I+L D RYA          R G L  LP W++ S           +  + FF
Sbjct:    1 MESKSGRFPFPFQPYPIQESFMEALYTALDQRKVGIFESPTGTGKSLSLICGALTWLRDYEEQRKQEAARLLEGQKDSDVVKEKNSNSGPPEPDWVSEFVQKKAERDMVNKLKADEDDE------------------AVKLLQLSREGAEPETHSPEEEGLIVAEYESDDEATPKSRLCDDDNDDDDDLEEEHVTKIYYCSRTHSQLAQFVHEVQKSPYGDAVRLVNLGSRQNLCINPEVVRLGNVQMMNERCLEMQKNKHEKRQKASDSESKRSRGLAKATCVFSRFENLMAMKDEVLVKVRDVEQLIQHGRETHTCPYYSTRMSIPAAQVVVLPYQSLLHASTRKASGIKLKDQIVIIDEAHNLMDTISAIHSAEISGGQLCRAHSQLSQYCERYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVGQNPNTQSCQTGSELLTINDFLFKAQVDNINLFKVQKYFEKSMISRKLCGFAEKYEGSGINTHSSSKNKENRRTEGLGRFLQTLQSKPTDVSEQQMAVEDKPIMASPMMLAESFLFALTNANKDGRVVIQRQACVAQSSLKFLLLNAAVHFAQILQECRAVIIAGGTMQPVADFKEQLLFSAGVTEERILEFSCGHVIPPENILPIV-LCAGPSGQQLEFTFQTRDSPQMMEETGRVLSNLCNIVPGGVVCFFPSYEYEKRILGHWESTGILQRLQSKKKIFQEPKKASQVEQVLSEYSK---------CIQRCSNIGGGQTGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKHMPHVAGKSPGKALVESLCMKAVNQSIGRAIRHRGDYACIVLCDHRYA----------RTGTLQKLPEWIRSSTHTHATFGPAFASARRFF 852          

Query:   25 MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNE---LIKNKLEIKQIEDDSQN----DFDWINAYAQSK-------------------KSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVSND---------IENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQK-PIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI-DSYSSLSCV---------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRP------RQSSALFGGNQLIKENQMD---SEKATDE---LGNAMLTVRNFIAAVYYS-LDASILVEKDV-----GLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
            M ++   F FP++PYP Q   M  LY  +++RK+GIFESPTGTGKSLS++C +L WL   +E +  E   L++ + +   +++ + N    + DW++ + Q K                   + +L +   N  L              +K   ++    +   +S +E  E   V  Y SD+E +            ++   E  +TKIYYCSRTHSQL Q + E+ K+ Y D +     GSRQNLCIN  V +L ++ ++NE+CL++QK    K  + +++ +K+ +    A C F  +E +  +   ++    D+EQL+  G ++  CP+Y  + S   A +V++PYQ++L+ + R AS I++KD IVI DEAHNL DTIS ++S ++    L     QL  Y  +Y  R  +KNL+Y++Q+  +   L+  +  K+  + ++ SC          +FLFK  ++ + L ++  + +KS ++ KL       E   +           R++  L    Q ++    D    + A ++   + + M+   +F+ A+  +  D  +++++        L FL+++   +   I+ +CR++I+ GGTMQP +DF  +L  +A    +RI  FSC HVI  +  + ++ L        L FTF+ R++  M++ TG +  ++ +  P GVV FF SY    +I+  W+S G+L  ++  K ++ EPK++ Q E V++ ++K          ++  +       GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  +SP LQEKM+Y++K      G    + +  +L MK VNQ+IGRAIRH+ D+A I+L D RYA          R G L  LP W++ S           +  + FF
Sbjct:    1 MESKSGRFPFPFQPYPIQESFMEALYTALDQRKVGIFESPTGTGKSLSLICGALTWLRDYEEQRKQEAARLLEGQKDSDVVKEKNSNSGPPEPDWVSEFVQKKAERDMVNKLKDEELKRKKREERLEMIRHNAQLRYAMKRKADEDDEAVKLLQLSREGAEPETHSPEE--EGLIVAEYESDDEATPKSRLCDDDNDDDDDLEEEHVTKIYYCSRTHSQLAQFVHEVQKSPYGDAVRLVNLGSRQNLCINPEVVRLGNVQMMNERCLEMQKNKHEKRQKASDSESKRSRGLAKATCVFSRFENLMAMKDEVLVKVRDVEQLIQHGRETHTCPYYSTRMSIPAAQVVVLPYQSLLHASTRKASGIKLKDQIVIIDEAHNLMDTISAIHSAEISGGQLCRAHSQLSQYCERYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVGQNPNTQSCQTGSELLTINDFLFKAQVDNINLFKVQKYFEKSMISRKLCGFAEKYEGSGINTHSSSKNKENRRTEGLGRFLQTLQSKPTDVSEQQMAVEDKPIMASPMMLAESFLFALTNANKDGRVVIQRQACVAQSSLKFLLLNAAVHFAQILQECRAVIIAGGTMQPVADFKEQLLFSAGVTEERILEFSCGHVIPPENILPIV-LCAGPSGQQLEFTFQTRDSPQMMEETGRVLSNLCNIVPGGVVCFFPSYEYEKRILGHWESTGILQRLQSKKKIFQEPKKASQVEQVLSEYSK---------CIQRCSNIGGGQTGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKHMPHVAGKSPGKALVESLCMKAVNQSIGRAIRHRGDYACIVLCDHRYA----------RTGTLQKLPEWIRSSTHTHATFGPAFASARRFF 881          

Query:  538 ITKIYYCSRTHSQLNQVLQELLK--------TSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHP--MDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISD---VNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEF-----VSRKIDSY----------------SSLSCVEFL------FKTYLN-EMKLDRILN--------------FIDKSKL---AYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVS 2478
            +TK+ YCSRT  ++ +V++EL K        T   +        SR+NLCI+  V+ L+    ++ KC  L          +   A+ +       C F  YE+ + V + +   P   +++ L   G + G CP++  + +   A++V+  Y  +L+P  A L SK   K ++V+FDEAHN+ +   D   VN  +  L    T ++ L++ I +  +  ++K       L   +  L+E      V+R+ D Y                 S+   E        F  YL   +++  ++                ID+  L   A +LR+ +R +E  D+    P    + F    L+           +   +   T+ N +                  L F  +DP   +K +  + +++I+  GT+ P  D   R+         R  T +   +  A+  +  + +G  +  V +   FE R + A+I+  G++ L + +  P+G+V FF+SY  M+ I+  W  +G+L  I++ K ++IE + + +                    +  +  + ++ +GA+L +V   K+SEGI+F     R VI+ G+PY  T+S IL+ ++ Y+  Q+    +  +  + AM+   Q +GRAIR K D+  +I  D+RYA   K       +GK  LP W+++ ++
Sbjct:   67 VTKLVYCSRTVPEIEKVVEELRKLMDYYSKQTGVKNDFLALALSSRKNLCIHPEVSSLRFGKEVDGKCHSLTA--------SYIRAQHQSNPNQPVCQF--YEEFDNVGRQVPIPPGIYNLDDLKDFGRRKGWCPYFLARYALLHANIVVYSYHYLLDPKIADLVSKELAKKSVVVFDEAHNIDNVCIDSMSVNITRRTLDRCQTNVETLQNTISRIKETDAAK-------LREEYRRLVEGLKEANVARETDIYLSNPVLPDEILQEAVPGSIRTAEHFVGFMKRFLEYLKARLRIHHVVQESAPQFLKDIFEKVCIDRKPLRFCAERLRSLLRTLEIADIADFSPITLISHFA--TLVSTYSKGFTIIIEPFEDKTPTIANPV------------------LHFSCMDPSIAIKPVFGRFQTVIITSGTLSPL-DIYPRILDF------RPVTMASFTMTLARTCLCPLIVGRGNDQVAMTSKFETREDFAVIRNYGNLLLEMSAIVPDGIVAFFTSYMYMENIVASWYEQGILENIQRNKLIFIETQDAAETSMA----------------LEKYQEACENGRGAILLSVARGKVSEGIDFVHHFGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGLMIFADKRYARADK-------RGK--LPRWIQEHLT 702          

Query: 1570 LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCE----HVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNE--NVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSES---SRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            L+F  ++P     D+ +  RS+++  GT+ P   FS+ L             FS +    HVIN K Q+ V T+G   +   L  TF++    A     G + L +      GV+ F  SY ++DK+ + W + G+  ++++ K+V  EP+   + +   ++  + +          +R   A  +   GA+L AV   K+SEG++F+D+ AR V+ +GIP+P  +   ++ KM Y +K   S         Y   A + +NQA+GR IRH+ND+ A+IL+D+R+    + + N   K   GL  W++  V   +     +  LKSF Q
Sbjct:  617 LSFWCLNPAVAFSDLSSTVRSIVLTSGTLSPMGSFSSELGIK----------FSIQLEANHVIN-KSQVWVGTIGAGPQGRKLCATFQHAETFAFQDEVGALLLKVCHTVSRGVLCFLPSYKMLDKLRDRWTNTGLWDKLEECKTVITEPRGGGKGDFDELLQTYYE---------AIRGTAAKGEKRDGALLVAVCRGKVSEGLDFTDDNARAVVTIGIPFPNIKDLQVELKMKYNDKHAKSRGLLPGGRWYEIQAYRALNQALGRCIRHRNDWGALILVDDRF----RTNPN---KYITGLSKWVRQLVRHHDTFTGAMQSLKSFSQ 918          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLD-LQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLL 1176
            I KI++ +RTH Q+ Q+ +EL +T Y+  +      SR + C++  V  +   N  NE+C + L+   G++ +    + K R  +T           ++ V  + +    DIE+LV  G K   C +Y  ++   +A +V  PY  +L+P  R + +I +K+ IV+ DEAHN+ D   +  S  L  + L+    ++   +   ++R   + LL
Sbjct:  270 IPKIFFGTRTHKQITQIARELKRTLYS-TVPMTILSSRDHTCVHPEV--VPHANR-NERCKEFLEAKNGRSCRYYHNVHKMRDQST-----------LQWV--HGLHQAWDIEELVRLGGKLRSCAYYAARELMQEACIVFCPYNYLLDPLIRESMEINLKEQIVVLDEAHNIEDCARESASFTLNQAQLLLARDEIDGMVTHNIRRDQHRPLL 466          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
            NFP + YP Q+ +M+ +   +   +  + ESPTG+GKSL++LCS+L W
Sbjct:   16 NFPCKAYPSQLAMMNSIIRGLNNGQHCLLESPTGSGKSLALLCSALAW 63          

Query: 1570 LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCE----HVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNE--NVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSES---SRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            L+F  ++P     D+ +  RS+++  GT+ P   FS+ L             FS +    HVIN K Q+ V T+G   +   L  TF++    A     G + L +      GV+ F  SY ++DK+ + W + G+  ++++ K+V  EP+   + +   ++  + +          +R   A  +   GA+L AV   K+SEG++F+D+ AR V+ +GIP+P  +   ++ KM Y +K   S         Y   A + +NQA+GR IRH+ND+ A+IL+D+R+    + + N   K   GL  W++  V   +     +  LKSF Q
Sbjct:  617 LSFWCLNPAVAFSDLSSTVRSIVLTSGTLSPMGSFSSELGIK----------FSIQLEANHVIN-KSQVWVGTIGAGPQGRKLCATFQHAETFAFQDEVGALLLKVCHTVSRGVLCFLPSYKMLDKLRDRWTNTGLWDKLEECKTVITEPRGGGKGDFDELLQTYYE---------AIRGTAAKGEKRDGALLVAVCRGKVSEGLDFTDDNARAVVTIGIPFPNIKDLQVELKMKYNDKHAKSRGLLPGGRWYEIQAYRALNQALGRCIRHRNDWGALILVDDRF----RTNPN---KYITGLSKWVRQLVRHHDTFTGAMQSLKSFSQ 918          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLD-LQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLL 1176
            I KI++ +RTH Q+ Q+ +EL +T Y+  +      SR + C++  V  +   N  NE+C + L+   G++ +    + K R  +T           ++ V  + +    DIE+LV  G K   C +Y  ++   +A +V  PY  +L+P  R + +I +K+ IV+ DEAHN+ D   +  S  L  + L+    ++   +   ++R   + LL
Sbjct:  270 IPKIFFGTRTHKQITQIARELKRTLYS-TVPMTILSSRDHTCVHPEV--VPHANR-NERCKEFLEAKNGRSCRYYHNVHKMRDQST-----------LQWV--HGLHQAWDIEELVRLGGKLRSCAYYAARELMQEACIVFCPYNYLLDPLIRESMEINLKEQIVVLDEAHNIEDCARESASFTLNQAQLLLARDEIDGMVTHNIRRDQHRPLL 466          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
            NFP + YP Q+ +M+ +   +   +  + ESPTG+GKSL++LCS+L W
Sbjct:   16 NFPCKAYPSQLAMMNSIIRGLNNGQHCLLESPTGSGKSLALLCSALAW 63          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL----LVNQENQMNELIKNKLEIKQIEDD-SQNDFDWINAYAQSK-----KSKLN----LTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQ--------------ESNEENFVVNYNSDEEVSNDIENQENEGS-----ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCV-----------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQM--------------DSEKATDELGNAMLTVRNFIAAVYYS-LDASILVE-----KDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAM----IKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLG-LPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            F FPYEPYP Q + M +LY  +E  K+GIFESPTGTGKSLS++C +L WL       ++ +   L     E+K+ +   S  + DWI  + Q K     K+K+        + E+  K+     Q+K    +K   ++ T +    S Q              +  +E  +V Y SDEE     +  E+E       +TKIYYCSRTHSQL+Q + E+ K+ +  +      GSRQN+C+N  V +L ++ LIN++C+++Q+   K ++  +   +K++  + A C F SYE+++ +    +    DIEQLV    +   CP+Y  + +   A +V++PYQ +L+ ++R AS I++KD +VI DEAHNL DTI+ + S ++  + L     QL  Y+ +Y  R  +KNL+Y++QL  +    ++ +   +    S   V           +FLF + ++ + L +I  +  KS ++ KL   +   +  +  +       A  G  Q +++                 D+E       + ++ +  F++A+  +  D  +++          L FL+++P  +  +++ +CRS+I+ GGTMQP SDF  +L  +A    +RI  FSC HVI A+  + ++ L     N  L FT++ R+   M    +  TG I  ++ +F P G+V FF SY    +I E W+  G+L  +   K ++ EPK++ Q + V+  ++K          ++N + S  +  GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  RSP LQEKMSY++K      G  + R++  NL MK VNQ+IGRAIRH+ D+A+I+LLD RY+          R   LG LP W++ S  ++ N  +  + ++ FFQ
Sbjct:   13 FPFPYEPYPIQEQFMEKLYQALEAGKVGIFESPTGTGKSLSLICGALTWLQDFETKKRQEEAQALSVADTELKEKDTSASSTEPDWIAQFVQMKEEMDIKNKIKEEQLRRKKREEHLKQMKHNVQLKFASKRKREEDDETMRLLQLSQQILSGGGEKEALELDQEEQELLLVEYESDEETKKGPDRLEDEEDLEEEHVTKIYYCSRTHSQLSQFVHEVQKSPFGKQTRLVSLGSRQNMCVNDDVRRLGNVQLINDRCMEMQR--NKHEKKNKEPERKKRQESRAACPFYSYEQMQFLRDETLVEVKDIEQLVSLAREVKACPYYSSRYAIPTAQVVVLPYQMLLHESSRKASGIKLKDQVVIIDEAHNLIDTITCMYSSQVSGAQLCQAHSQLMQYMDRYRSRLKAKNLMYVKQLVFLLEKFVQVMGGNVKQNPSFQKVAQDGTTLKSINDFLFHSQIDNINLFKIQRYCTKSMISRKLSGFVEKFKGTETCLANKESQKA--GLQQFLQDLSQKSRHTVGAPEGALEDAENGQLRTASPLMQIEGFLSALTNANQDGRVILHMQGTVAQSSLKFLMLNPAVHFAEVLKECRSVIIAGGTMQPVSDFKQQLLISAGLSPERITEFSCGHVIPAENILPIV-LCSGPTNQQLEFTYQKRDLPEMESIFMDETGRILTNLCNFVPGGLVCFFPSYEYQKRIQEHWEKSGLLKRLALKKKIFQEPKRANQVDQVLVEYSK---------CIKNCSQSGGAQNGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIRSPELQEKMSYLDKTLPKTEGVSAGRVLIENLCMKAVNQSIGRAIRHRGDYASIVLLDHRYS----------RPAILGKLPQWIRSSTQVKPNFGAAFATIRKFFQ 889          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL----LVNQENQMNELIKNKLEIKQIEDD-SQNDFDWINAYAQSK-----KSKLNLTDQN------EXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCV-----------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYS-LDASILVE-----KDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAM----IKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLG-LPSWLKDSVSIQNNTNSLISELK 2517
            F FPYEPYP Q + M +LY  +E  K+GIFESPTGTGKSLS++C +L WL       ++ +   L     E+K+ +   S  + DWI  + Q K     K+K+ +T           L +++   + ++L++L ++ ++    K+    +QE  +E  +V Y SDEE     E  +   S++ IYYCSRTHSQL+Q + E+ K+ +  +      GSRQN+C+N  V +L ++ LIN++C+++Q+   K ++  +   +K++  + A C F SYE+++ +    +    DIEQLV    +   CP+Y  + +   A +V++PYQ +L+ ++R AS I++KD +VI DEAHNL DTI+ + S ++  + L     QL  Y+ +Y  R  +KNL+Y++QL  +    ++ +   +    S   V           +FLF + ++ + L +I  +  KS ++ K               VR +  S L  G  + + N  D+E       + ++ +  F++A+  +  D  +++          L FL+++P  +  +++ +CRS+I+ GGTMQP SDF  +L  +A    +RI  FSC HVI A+  + ++ L     N  L FT++ R+   M    +  TG I  ++ +F P G+V FF SY    +I E W+  G+L  +   K ++ EPK++ Q + V+  ++K          ++N + S  +  GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  RSP LQEKMSY++K      G  + R++  NL MK VNQ+IGRAIRH+ D+A+I+LLD RY+          R   LG LP W++ S  ++ N  +  + ++
Sbjct:   21 FPFPYEPYPIQEQFMEKLYQALEAGKVGIFESPTGTGKSLSLICGALTWLQDFETKKRQEEAQALSVADTELKEKDTSASSTEPDWIAQFVQMKEEMDIKNKIKVTCLTLDLIFPSCLLQREEDDETMRLLQLSQQILSGGGEKEALELDQE-EQELLLVEYESDEETKKGPEY-DIAVSLSCIYYCSRTHSQLSQFVHEVQKSPFGKQTRLVSLGSRQNMCVNDDVRRLGNVQLINDRCMEMQR--NKHEKKNKEPERKKRQESRAACPFYSYEQMQFLRDETLVEVKDIEQLVSLAREVKACPYYSSRYAIPTAQVVVLPYQMLLHESSRKASGIKLKDQVVIIDEAHNLIDTITCMYSSQVSGAQLCQAHSQLMQYMDRYRSRLKAKNLMYVKQLVFLLEKFVQVMGGNVKQNPSFQKVAQDGTTLKSINDFLFHSQIDNINLFKIQRYCTKSMISRK---------------VRKQTYSLLLIGQAVTRLNLYDAENGQLRTASPLMQIEGFLSALTNANQDGRVILHMQGTVAQSSLKFLMLNPAVHFAEVLKECRSVIIAGGTMQPVSDFKQQLLISAGLSPERITEFSCGHVIPAENILPIV-LCSGPTNQQLEFTYQKRDLPEMESIFMDETGRILTNLCNFVPGGLVCFFPSYEYQKRIQEHWEKSGLLKRLALKKKIFQEPKRANQVDQVLVEYSK---------CIKNCSQSGGAQNGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIRSPELQEKMSYLDKTLPKTEGVSAGRVLIENLCMKAVNQSIGRAIRHRGDYASIVLLDHRYS----------RPAILGKLPQWIRSSTQVKPNFGAAFATIR 847          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL----LVNQENQMNELIKNKLEIKQIEDD-SQNDFDWINAYAQSK-------KSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSN------QESNEENFVVNYNSDEEVSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCV-----------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQS-----SALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAM----IKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLG-LPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            F FPYEPYP Q + M +LY  +E  K+GIFESPTGTGKSLS++C +L WL       ++ +   L     E+K+ +   S  + DWI  + Q K       K K     + +  E  K +   ++L    K  + N  F      N       +  +E  +V Y SDEE     E          IYYCSRTHSQL+Q + E+ K+ +  +      GSRQN+C+N  V +L ++ LIN++C+++Q+   K ++  +   +K++  + A C F SYE+++ +    +    DIEQLV    +   CP+Y  + +   A +V++PYQ +L+ ++R AS I++KD +VI DEAHNL DTI+ + S ++  + L     QL  Y+ +Y  R  +KNL+Y++QL  +    ++ +   +    S   V           +FLF + ++ + L +++       L      ++ + E G +    P        SAL   NQ                G  +L ++  +A                 L FL+++P  +  +++ +CRS+I+ GGTMQP SDF  +L  +A    +RI  FSC HVI A+  + ++ L     N  L FT++ R+   M    +  TG I  ++ +F P G+V FF SY    +I E W+  G+L  +   K ++ EPK++ Q + V+  ++K                S  +  GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  RSP LQEKMSY++K      G  + R++  NL MK VNQ+IGRAIRH+ D+A+I+LLD RY+          R   LG LP W++ S  ++ N  +  + ++ FFQ
Sbjct:   14 FPFPYEPYPIQEQFMEKLYQALEAGKVGIFESPTGTGKSLSLICGALTWLQDFETKKRQEEAQALSVADTELKEKDTSASSTEPDWIAQFVQMKEEMDIKNKIKEEQLRRKKREEHLKQMKHNVQLKFASKRKVTNLLFLSVIGQNTVTLELDQEEQELLLVEYESDEETKKGPEYD------IAIYYCSRTHSQLSQFVHEVQKSPFGKQTRLVSLGSRQNMCVNDDVRRLGNVQLINDRCMEMQR--NKHEKKNKEPERKKRQESRAACPFYSYEQMQFLRDETLVEVKDIEQLVSLAREVKACPYYSSRYAIPTAQVVVLPYQMLLHESSRKASGIKLKDQVVIIDEAHNLIDTITCMYSSQVSGAQLCQAHSQLMQYMDRYRSRLKAKNLMYVKQLVFLLEKFVQVMGGNVKQNPSFQKVAQDGTTLKSINDFLFHSQIDNINLFKLIFMFVFMLLVGAPEGALEDAENGQLRTASPLMQIEGFLSALTNANQD---------------GRVILHMQGTVA--------------QSSLKFLMLNPAVHFAEVLKECRSVIIAGGTMQPVSDFKQQLLISAGLSPERITEFSCGHVIPAENILPIV-LCSGPTNQQLEFTYQKRDLPEMESIFMDETGRILTNLCNFVPGGLVCFFPSYEYQKRIQEHWEKSGLLKRLALKKKIFQEPKRANQVDQVLVEYSK-------------CIKSGGAQNGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIRSPELQEKMSYLDKTLPKTEGVSAGRVLIENLCMKAVNQSIGRAIRHRGDYASIVLLDHRYS----------RPAILGKLPQWIRSSTQVKPNFGAAFATIRKFFQ 823          

Query:  541 TKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQS-----SALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAM----IKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLG-LPSWLKDSVSIQNNTNSLISELKSFFQ 2529
             +IYYCSRTHSQL+Q + E+ K+ +  +      GSRQN+C+N  V +L ++ LIN++C+++Q+             K  +  + A C F SYE+++ +    +    DIEQLV    +   CP+Y  + +   A +V++PYQ +L+ ++R AS I++KD +VI DEAHNL DTI+ + S ++  + L     QL  Y+ +Y  R  +KNL+Y++QL  +    ++ +  K+          F+F   L                L      ++ + E G +    P        SAL   NQ                G  +L ++  +A                 L FL+++P  +  +++ +CRS+I+ GGTMQP SDF  +L  +A    +RI  FSC HVI A+  + ++ L     N  L FT++ R+   M    +  TG I  ++ +F P G+V FF SY    +I E W+  G+L  +   K ++ EPK++ Q + V+  ++K          ++N + S  +  GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  RSP LQEKMSY++K      G  + R++  NL MK VNQ+IGRAIRH+ D+A+I+LLD RY+          R   LG LP W++ S  ++ N  +  + ++ FFQ
Sbjct:  199 VQIYYCSRTHSQLSQFVHEVQKSPFGKQTRLVSLGSRQNMCVNDDVRRLGNVQLINDRCMEMQR------------NKHGEQESRAACPFYSYEQMQFLRDETLVEVKDIEQLVSLAREVKACPYYSSRYAIPTAQVVVLPYQMLLHESSRKASGIKLKDQVVIIDEAHNLIDTITCMYSSQVSGAQLCQAHSQLMQYMDRYRSRLKAKNLMYVKQLVFLLEKFVQVMGGKLI---------FMFVFML----------------LVGAPEGALEDAENGQLRTASPLMQIEGFLSALTNANQD---------------GRVILHMQGTVA--------------QSSLKFLMLNPAVHFAEVLKECRSVIIAGGTMQPVSDFKQQLLISAGLSPERITEFSCGHVIPAENILPIV-LCSGPTNQQLEFTYQKRDLPEMESIFMDETGRILTNLCNFVPGGLVCFFPSYEYQKRIQEHWEKSGLLKRLALKKKIFQEPKRANQVDQVLVEYSK---------CIKNCSQSGGAQNGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIRSPELQEKMSYLDKTLPKTEGVSAGRVLIENLCMKAVNQSIGRAIRHRGDYASIVLLDHRYS----------RPAILGKLPQWIRSSTQVKPNFGAAFATIRKFFQ 789          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL----LVNQENQMNELIKNKLEIKQIEDD-SQNDFDWINAYAQSKK 315
            F FPYEPYP Q + M +LY  +E  K+GIFESPTGTGKSLS++C +L WL       ++ +   L     E+K+ +   S  + DWI  + Q K+
Sbjct:   13 FPFPYEPYPIQEQFMEKLYQALEAGKVGIFESPTGTGKSLSLICGALTWLQDFETKKRQEEAQALSVADTELKEKDTSASSTEPDWIAQFVQMKE 107          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL----LVNQENQMNELIKNKLEIKQIEDD-SQNDFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSI------NNTTFKDCNYSNQ--------------ESNEENFVVNYNSDEEVSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCV-----------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYS-LDASILVE-----KDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAM----IKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEK 2268
            F FPYEPYP Q + M +LY  +E  K+GIFESPTGTGKSLS++C +L WL       ++ +   L     E+K+ +   S  + DWI  + Q K+    +  +N+        +     + L   S       ++ T +    S Q              +  +E  +V Y SDEE     E          IYYCSRTHSQL+Q + E+ K+ +  +      GSRQN+C+N  V +L ++ LIN++C+++Q+   K ++  +   +K++  + A C F SYE+++ +    +    DIEQLV    +   CP+Y  + +   A +V++PYQ +L+ ++R AS I++KD +VI DEAHNL DTI+ + S ++  + L     QL  Y+ +Y  R  +KNL+Y++QL  +    ++ +   +    S   V           +FLF + ++ + L +I  +  KS ++ KL           V ++       L G  +   E   D+E       + ++ +  F++A+  +  D  +++          L FL+++P  +  +++ +CRS+I+ GGTMQP SDF  +L  +A    +RI  FSC HVI A+  + ++ L     N  L FT++ R+   M    +  TG I  ++ +F P G+V FF SY    +I E W+  G+L  +   K V         ++N                   N + S  +  GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  RSP LQEKMSY++K
Sbjct:   13 FPFPYEPYPIQEQFMEKLYQALEAGKVGIFESPTGTGKSLSLICGALTWLQDFETKKRQEEAQALSVADTELKEKDTSASSTEPDWIAQFVQMKE---EMDIKNKIKCYFICAISSSLTLDLIFPSCLLQREEDDETMRLLQLSQQILSGGGEKEALELDQEEQELLLVEYESDEETKKGPE-------YDIIYYCSRTHSQLSQFVHEVQKSPFGKQTRLVSLGSRQNMCVNDDVRRLGNVQLINDRCMEMQR--NKHEKKNKEPERKKRQESRAACPFYSYEQMQFLRDETLVEVKDIEQLVSLAREVKACPYYSSRYAIPTAQVVVLPYQMLLHESSRKASGIKLKDQVVIIDEAHNLIDTITCMYSSQVSGAQLCQAHSQLMQYMDRYRSRLKAKNLMYVKQLVFLLEKFVQVMGGNVKQNPSFQKVAQDGTTLKSINDFLFHSQIDNINLFKIQRYCTKSMISRKLIFMF-------VFML-------LVGAPEGALE---DAENGQLRTASPLMQIEGFLSALTNANQDGRVILHMQGTVAQSSLKFLMLNPAVHFAEVLKECRSVIIAGGTMQPVSDFKQQLLISAGLSPERITEFSCGHVIPAENILPIV-LCSGPTNQQLEFTYQKRDLPEMESIFMDETGRILTNLCNFVPGGLVCFFPSYEYQKRIQEHWEKSGLLKRLALKKKVI--------HQN-------------------NCSQSGGAQNGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIRSPELQEKMSYLDK 742          

Query:   76 QMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL--LVNQENQMNELI-----------KNKL----EIKQIEDDSQ--NDFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVV-NYNSDEEVSND----IENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNA--------MLTVRNFIAAVYYS-LDASILVEKD--VG---LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEK-----QYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            Q   M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL     ++ Q   L+           KN L      ++  D  +   + DW+  + Q KK + +L ++  + +K +    +  L   ++     T  +       E  EE+ V+  Y SDEE         E+   E  ITKIYYCSRTHSQL Q ++E+LK+ +  +      GSRQ LC+N  V  L S+ L+N++C+D+Q+   + +   E   K+++      C F ++E++E +   I+    D+EQLV  G ++  CP+YG + +   A LV++PY  +L+ A R A+ I ++  +VI DEAHNL DTI++++S ++  S L     QL  Y+ +Y +R  +KNL+Y++Q+  +    +  +   +    +  SLS          +FLF++ ++ + L ++  +++KS L+ KL             +   +++  L G  Q +K  Q    + + E G A        ++ +  F+AA+  +  D  ++V +   VG   L FL+++P  +   +V +CR++++ GGTMQP SDF  +L   +   + R+  FSC HVI     + ++     S N  L FT++ R    M++ TG I  ++ +  P GVV F  SY  + ++   W   G+L+ +   K ++ EPK++ Q E V+  ++K          + + + S     GA+L +V+G KMSEGINFSD+L R V++VG+PYP  +SP LQEKM+Y+ +     Q       ++  NL MK +NQ+IGRAIRH+ DFA+I+LLD RYA  + +++         LP+W++D V ++       + ++ F +
Sbjct:   23 QKDFMAELYKVLEGGKIGIFESPTGTGKSLSLICGALSWLRDFEKKKLQAEALLLAPGSGPPSSEKNSLLTSSSCQEPTDTPRPAGEPDWVTEFVQ-KKEERDLVERLREEQKHEEEETEALLRLSREMLDAGTGPE--QLEQLECGEEHLVLAEYESDEERRGSRVDEAEDDLEEEHITKIYYCSRTHSQLAQFVREVLKSPFGKETRLVSLGSRQTLCVNEDVKNLGSVQLMNDRCVDMQRSKREKNGTGEDKPKRKRQKIQTSCPFYNHEQMELLRDEILLEVKDMEQLVALGKEARACPYYGSRFAIPAAQLVVLPYPMLLHAATRQAAGIRLQGQVVIIDEAHNLIDTITNIHSTEVNGSQLCQAHSQLLQYMERYRKRLKAKNLMYIKQILYLLEKFVAVLGGNVKQNPTTQSLSQTGSELKSINDFLFQSQVDNINLFKVQRYLEKSMLSRKLFGFTECFGVVLPSLSDSQENRGLAGFQQFLKSLQSGPTEDSPEEGQAVALRPASPLMHIEAFLAALTTANQDGRVIVNRQGSVGQSSLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPMSDFREQLLACSGVEAGRVVEFSCGHVIPPDNILPLIICSGPS-NQQLEFTYQRRELPQMVEETGRILCNLCNVVPGGVVCFLPSYEYLRQVHAHWDKTGLLTRLSVRKKIFQEPKRASQVEQVLMAYSK---------CIMSCSHSEGHLTGALLLSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMAYLNQTLPRTQGQPLPGTVLIENLCMKAINQSIGRAIRHQRDFASIVLLDHRYARPSILAK---------LPAWIRDRVEVKATFGPAFAAVRKFHR 872          

Query:  451 ESNEENFVV-NYNSDEEVSND----IENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNA--------MLTVRNFIAAVYYS-LDASILVEKD--VG---LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEK-----QYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            E  EE+ V+  Y SDEE         E+   E  ITKIYYCSRTHSQL Q ++E+LK+ +  +      GSRQ LC+N  V  L S+ L+N++C+D+Q+   + +   E   K+++      C F ++E++E +   I+    D+EQLV  G ++  CP+YG + +   A LV++PY  +L+ A R A+ I ++  +VI DEAHNL DTI++++S ++  S L     QL  Y+ +Y +R  +KNL+Y++Q+  +    +  +   +    +  SLS          +FLF++ ++ + L ++  +++KS L+ KL             +   +++  L G  Q +K  Q    + + E G A        ++ +  F+AA+  +  D  ++V +   VG   L FL+++P  +   +V +CR++++ GGTMQP SDF  +L   +   + R+  FSC HVI     + ++     S N  L FT++ R    M++ TG I  ++ +  P GVV F  SY  + ++   W   G+L+ +   K ++ EPK++ Q E V+  ++K          + + + S     GA+L +V+G KMSEGINFSD+L R V++VG+PYP  +SP LQEKM+Y+ +     Q       ++  NL MK +NQ+IGRAIRH+ DFA+I+LLD RYA  + +++         LP+W++D V ++       + ++ F +
Sbjct:  190 ECGEEHLVLAEYESDEERRGSRVDEAEDDLEEEHITKIYYCSRTHSQLAQFVREVLKSPFGKETRLVSLGSRQTLCVNEDVKNLGSVQLMNDRCVDMQRSKREKNGTGEDKPKRKRQKIQTSCPFYNHEQMELLRDEILLEVKDMEQLVALGKEARACPYYGSRFAIPAAQLVVLPYPMLLHAATRQAAGIRLQGQVVIIDEAHNLIDTITNIHSTEVNGSQLCQAHSQLLQYMERYRKRLKAKNLMYIKQILYLLEKFVAVLGGNVKQNPTTQSLSQTGSELKSINDFLFQSQVDNINLFKVQRYLEKSMLSRKLFGFTECFGVVLPSLSDSQENRGLAGFQQFLKSLQSGPTEDSPEEGQAVALRPASPLMHIEAFLAALTTANQDGRVIVNRQGSVGQSSLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPMSDFREQLLACSGVEAGRVVEFSCGHVIPPDNILPLIICSGPS-NQQLEFTYQRRELPQMVEETGRILCNLCNVVPGGVVCFLPSYEYLRQVHAHWDKTGLLTRLSVRKKIFQEPKRASQVEQVLMAYSK---------CIMSCSHSEGHLTGALLLSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMAYLNQTLPRTQGQPLPGTVLIENLCMKAINQSIGRAIRHQRDFASIVLLDHRYARPSILAK---------LPAWIRDRVEVKATFGPAFAAVRKFHR 898          

Query:   76 QMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
            Q   M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL
Sbjct:   23 QKDFMAELYKVLEGGKIGIFESPTGTGKSLSLICGALSWL 62          

Query: 1570 LTFLVVDPGKYLKDIVNQ-CRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSC---EHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSE-------SSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            L++    P + ++++V Q  R++I+  GT+ P S F+  +         +I    C    H+I+ K Q+ V  +      V L   ++ R +E  + + G    +I    P+G+++FF SY VM+K +E WQ +G+  +++ LK +++EP+       VI  + +Q              AS  SN GA   AV   K SEG++FSD   R VI+ G+PYP    P +  KM ++++  G         S +  Y   A + VNQAIGR IRH++D+ AI L D R+A             +  LPSW++  + + +N   +I ++  FF+
Sbjct:  453 LSYWCFSPSQSMRELVCQGVRTLILTSGTLAPLSSFALEM---------QIPFPVCLENPHIID-KNQLWVGIVPRGPDGVQLSSAYDKRFSEECLSSLGKALSNIARVVPHGLLVFFPSYPVMEKSLEFWQVQGLARKVEALKPLFVEPRNKGSFSEVIDAYYQQ-------------VASPASN-GATFLAVCRGKASEGLDFSDMNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMRGRSGVGGQCLSGQEWYQQQASRAVNQAIGRVIRHRHDYGAIFLCDHRFA---------YADARAQLPSWVRPYLKVYDNFGHVIRDVAQFFR 750          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLK 1119
            I KI Y SRTHSQL QV++EL  T+Y  K+  C  GSR+ LCI+  V + +S ++    C                    RK      C F +  + + + +++    +DIE LV  G K   CP+Y  +    +A ++ MPY  +L+  +R A  I++K  +VIFDEAHN+     +  S  L    + +GL+
Sbjct:  106 IPKIIYASRTHSQLTQVIRELRNTAYRPKV--CVLGSREQLCIHPEVKKQESNHMQISLC--------------------RKKVASRSCHFYNNVEAKFLEQDLATPILDIEDLVKNGSKQKMCPYYLSRNMKQQADIIFMPYNYLLDAKSRKAHSIDLKGTVVIFDEAHNVEKICEESASFDLTPRDVASGLE 277          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
            +FP++PYP Q + M+++   ++K+  GI ESPTGTGK+L +LCS+L W
Sbjct:   12 DFPFQPYPCQQEYMTKVLECLQKKVNGILESPTGTGKTLCLLCSTLAW 59          

Query: 1570 LTFLVVDPGKYLKDIVNQ-CRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSC---EHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSE-------SSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            L++    P + ++++V Q  R++I+  GT+ P S F+  +         +I    C    H+I+ K Q+ V  +      V L   ++ R +E  + + G    +I    P+G+++FF SY VM+K +E WQ +G+  +++ LK +++EP+       VI  + +Q              AS  SN GA   AV   K SEG++FSD   R VI+ G+PYP    P +  KM ++++  G         S +  Y   A + VNQAIGR IRH++D+ AI L D R+A             +  LPSW++  + + +N   +I ++  FF+
Sbjct:  453 LSYWCFSPSQSMRELVCQGVRTLILTSGTLAPLSSFALEM---------QIPFPVCLENPHIID-KNQLWVGIVPRGPDGVQLSSAYDKRFSEECLSSLGKALSNIARVVPHGLLVFFPSYPVMEKSLEFWQVQGLARKVEALKPLFVEPRNKGSFSEVIDAYYQQ-------------VASPASN-GATFLAVCRGKASEGLDFSDMNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMRGRSGVGGQCLSGQEWYQQQASRAVNQAIGRVIRHRHDYGAIFLCDHRFA---------YADARAQLPSWVRPYLKVYDNFGHVIRDVAQFFR 750          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLK 1119
            I KI Y SRTHSQL QV++EL  T+Y  K+  C  GSR+ LCI+  V + +S ++    C                    RK      C F +  + + + +++    +DIE LV  G K   CP+Y  +    +A ++ MPY  +L+  +R A  I++K  +VIFDEAHN+     +  S  L    + +GL+
Sbjct:  106 IPKIIYASRTHSQLTQVIRELRNTAYRPKV--CVLGSREQLCIHPEVKKQESNHMQISLC--------------------RKKVASRSCHFYNNVEAKFLEQDLATPILDIEDLVKNGSKQKMCPYYLSRNMKQQADIIFMPYNYLLDAKSRKAHSIDLKGTVVIFDEAHNVEKICEESASFDLTPRDVASGLE 277          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
            +FP++PYP Q + M+++   ++K+  GI ESPTGTGK+L +LCS+L W
Sbjct:   12 DFPFQPYPCQQEYMTKVLECLQKKVNGILESPTGTGKTLCLLCSTLAW 59          

Query: 1570 LTFLVVDPGKYLKDIVNQ-CRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSC---EHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSE-------SSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            L++    P + ++++V Q  R++I+  GT+ P S F+  +         +I    C    H+I+ K Q+ V  +      V L   ++ R +E  + + G    +I    P+G+++FF SY VM+K +E WQ +G+  +++ LK +++EP+       VI  + +Q              AS  SN GA   AV   K SEG++FSD   R VI+ G+PYP    P +  KM ++++  G         S +  Y   A + VNQAIGR IRH++D+ AI L D R+A             +  LPSW++  + + +N   +I ++  FF+
Sbjct:  453 LSYWCFSPSQSMRELVCQGVRTLILTSGTLAPLSSFALEM---------QIPFPVCLENPHIID-KNQLWVGIVPRGPDGVQLSSAYDKRFSEECLSSLGKALSNIARVVPHGLLVFFPSYPVMEKSLEFWQVQGLARKVEALKPLFVEPRNKGSFSEVIDAYYQQ-------------VASPASN-GATFLAVCRGKASEGLDFSDMNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMRGRSGVGGQCLSGQEWYQQQASRAVNQAIGRVIRHRHDYGAIFLCDHRFA---------YADARAQLPSWVRPYLKVYDNFGHVIRDVAQFFR 750          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLK 1119
            I KI Y SRTHSQL QV++EL  T+Y  K+  C  GSR+ LCI+  V + +S ++    C                    RK      C F +  + + + +++    +DIE LV  G K   CP+Y  +    +A ++ MPY  +L+  +R A  I++K  +VIFDEAHN+     +  S  L    + +GL+
Sbjct:  106 IPKIIYASRTHSQLTQVIRELRNTAYRPKV--CVLGSREQLCIHPEVKKQESNHMQISLC--------------------RKKVASRSCHFYNNVEAKFLEQDLATPILDIEDLVKNGSKQKMCPYYLSRNMKQQADIIFMPYNYLLDAKSRKAHSIDLKGTVVIFDEAHNVEKICEESASFDLTPRDVASGLE 277          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
            +FP++PYP Q + M+++   ++K+  GI ESPTGTGK+L +LCS+L W
Sbjct:   12 DFPFQPYPCQQEYMTKVLECLQKKVNGILESPTGTGKTLCLLCSTLAW 59          

Query:   25 MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNE---LIKNKLEIKQIEDDSQN----DFDWINAYAQSK-------------------KSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVSND---------IENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQK-PIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI-DSYSSLSCV---------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRP------RQSSALFGGNQLIKENQMD---SEKATDE---LGNAMLTVRNFIAAVYYS-LDASILVEKDV-----GLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
            M ++   F FP++PYP Q   M  LY  +++RK+GIFESPTGTGKSLS++C +L WL   +E +  E   L++ + +   +++ + N    + DW++ + Q K                   + +L +   N  L              +K   ++    +   +S +E  E   V  Y SD+E +            ++   E  +TKIYYCSRTHSQL Q + E+ K+ Y D +     GSRQNLCIN  V +L ++ ++NE+CL++QK    K  + +++ +K+ +    A C F  +E +  +   ++    D+EQL+  G ++  CP+Y  + S   A +V++PYQ++L+ + R AS I++KD IVI DEAHNL DTIS ++S ++    L     QL  Y  +Y  R  +KNL+Y++Q+  +   L+  +  K+  + ++ SC          +FLFK  ++ + L ++  + +KS ++ KL       E   +           R++  L    Q ++    D    + A ++   + + M+   +F+ A+  +  D  +++++        L FL+++   +   I+ +CR++I+ GGTMQP +DF  +L  +A    +RI  FSC HVI  +  + ++ L        L FTF+ R++  M++ TG +  ++ +  P GVV FF SY    +I+  W+S G+L  ++  K ++ EPK++ Q E V++ ++K          ++  +       GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  +SP LQEKM+Y++K      G    + +  +L MK VNQ+IGRAIRH+ D+A I+L D RYA          R G L  LP W++ S           +  + FF
Sbjct:    1 MESKSGRFPFPFQPYPIQESFMEALYTALDQRKVGIFESPTGTGKSLSLICGALTWLRDYEEQRKQEAARLLEGQKDSDVVKEKNSNSGPPEPDWVSEFVQKKAERDMVNKLKDEELKRKKREERLEMIRHNAQLRYAMKRKADEDDEAVKLLQLSREGAEPETHSPEE--EGLIVAEYESDDEATPKSRLCDDDNDDDDDLEEEHVTKIYYCSRTHSQLAQFVHEVQKSPYGDAVRLVNLGSRQNLCINPEVVRLGNVQMMNERCLEMQKNKHEKRQKASDSESKRSRGLAKATCVFSRFENLMAMKDEVLVKVRDVEQLIQHGRETHTCPYYSTRMSIPAAQVVVLPYQSLLHASTRKASGIKLKDQIVIIDEAHNLMDTISAIHSAEISGGQLCRAHSQLSQYCERYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVGQNPNTQSCQTGSELLTINDFLFKAQVDNINLFKVQKYFEKSMISRKLCGFAEKYEGSGINTHSSSKNKENRRTEGLGRFLQTLQSKPTDVSEQQMAVEDKPIMASPMMLAESFLFALTNANKDGRVVIQRQACVAQSSLKFLLLNAAVHFAQILQECRAVIIAGGTMQPVADFKEQLLFSAGVTEERILEFSCGHVIPPENILPIV-LCAGPSGQQLEFTFQTRDSPQMMEETGRVLSNLCNIVPGGVVCFFPSYEYEKRILGHWESTGILQRLQSKKKIFQEPKKASQVEQVLSEYSK---------CIQRCSNIGGGQTGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKHMPHVAGKSPGKALVESLCMKAVNQSIGRAIRHRGDYACIVLCDHRYA----------RTGTLQKLPEWIRSSTHTHATFGPAFASARRFF 881          

Query:  451 ESNEENFVV-NYNSDEEVSND----IENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNA--------MLTVRNFIAAVYYS-LDASILVEKD--VG---LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEK-----QYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            E  EE+ V+  Y SDEE         E+   E  ITKIYYCSRTHSQL Q ++E+LK+ +  +      GSRQ LC+N  V  L S+ L+N++C+D+Q+   + +   E   K+++      C F ++E++E +   I+    D+EQLV  G ++  CP+YG + +   A LV++PY  +L+ A R A+ I ++  +VI DEAHNL DTI++++S ++  S L     QL  Y+ +Y +R  +KNL+Y++Q+  +    +  +   +    +  SLS          +FLF++ ++ + L ++  +++KS L+ KL             +   +++  L G  Q +K  Q    + + E G A        ++ +  F+AA+  +  D  ++V +   VG   L FL+++P  +   +V +CR++++ GGTMQP SDF  +L   +   + R+  FSC HVI     + ++     S N  L FT++ R    M++ TG I  ++ +  P GVV F  SY  + ++   W   G+L+ +   K ++ EPK++ Q E V+  ++K          + + + S     GA+L +V+G KMSEGINFSD+L R V++VG+PYP  +SP LQEKM+Y+ +     Q       ++  NL MK +NQ+IGRAIRH+ DFA+I+LLD RYA  + +++         LP+W++D V ++       + ++ F +
Sbjct:  190 ECGEEHLVLAEYESDEERRGSRVDEAEDDLEEEHITKIYYCSRTHSQLAQFVREVLKSPFGKETRLVSLGSRQTLCVNEDVKNLGSVQLMNDRCVDMQRSKREKNGTGEDKPKRKRQKIQTSCPFYNHEQMELLRDEILLEVKDMEQLVALGKEARACPYYGSRFAIPAAQLVVLPYPMLLHAATRQAAGIRLQGQVVIIDEAHNLIDTITNIHSTEVNGSQLCQAHSQLLQYMERYRKRLKAKNLMYIKQILYLLEKFVAVLGGNVKQNPTTQSLSQTGSELKSINDFLFQSQVDNINLFKVQRYLEKSMLSRKLFGFTECFGVVLPSLSDSQENRGLAGFQQFLKSLQSGPTEDSPEEGQAVALRPASPLMHIEAFLAALTTANQDGRVIVNRQGSVGQSSLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPMSDFREQLLACSGVEAGRVVEFSCGHVIPPDNILPLIICSGPS-NQQLEFTYQRRELPQMVEETGRILCNLCNVVPGGVVCFLPSYEYLRQVHAHWDKTGLLTRLSVRKKIFQEPKRASQVEQVLMAYSK---------CIMSCSHSEGHLTGALLLSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMAYLNQTLPRTQGQPLPGTVLIENLCMKAINQSIGRAIRHQRDFASIVLLDHRYARPSILAK---------LPAWIRDRVEVKATFGPAFAAVRKFHR 898          

Query:   76 QMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
            Q   M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL
Sbjct:   23 QKDFMAELYKVLEGGKIGIFESPTGTGKSLSLICGALSWL 62          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEI--KQIEDDSQNDFD-WINAYAQSKKSK---LNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVS--------NDIENQENEG-SITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGAC---CSFKSYEKIEEVSKNIIRHPM-DIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLI------KENQMDSEKATDELGNAMLTVRNFIAAVYYSL-DASILVEK---DVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            F+FP++PY  Q+ LM E+   IE+RKIGIFESPTGTGKSLSVLCS++ WL   +     +L     E+  K  E D     D W  A  +  +++     + +Q +  E+ +  +DQ +   ++         +D +   +  +E      YN+DE+          +D++ +E +     KI+Y SRTHSQL Q+ +EL KT +  +I TC   SR  LC+N  V +LK  +LINEKC++L+K      +  + L K     T  C   C F +  +IE+V   ++ + +    ++   G  S GCP++  +KS  +  LVL+PYQ +L+   R A  IE+KDN+++ DEAHN+ +TIS + S ++    L   L+ ++ Y   Y  +  + NLLY++QLE++ S ++ F++ +      ++  +      + E+ L ++  +++K+ L  K       ++  ++      +   L G  +L+       E + +       + + + ++++FI A+     D  I+VEK   +    F++++P   L ++V   R+ I++GGTM+P       L + +   +D I  FSC HVI+  Q + V T+       P + T++ R  +  +++      ++    PNGVVIF  SY+ +    ++ +  G+L  I++ K+V+ E +Q   +                  +   F+ +AK++KGA+LFAV+G KMSEGINF DEL R VI++G+PYP   S  L+E+M +++ Q  +    ++Y +L M  VNQAIGRAIRH+ D+AA+ L D+RYA      E+  RK    L +W+ D   ++     +I + +SFF+
Sbjct:    4 FSFPFQPYDIQLNLMREIRQCIEQRKIGIFESPTGTGKSLSVLCSTMTWLEAEELRISTDLSTRLGEVHTKITECDKITTADNWETAVREKMRAQDVETEILEQIQSRERLQSRIDQARRGMVEVSRKRKAPARDTDQFLEPQDEAAPSEEYNNDEKSEKQRDSDFFDDVDEEEEKPLKCLKIFYASRTHSQLEQLAEELAKTRFQPRIVTC--ASRGTLCVNEEVKKLKLNHLINEKCMELRKNGMSEKEKVQKLEKGTTKKTKTCATSCEFYNSTQIEDVVNGVLSNKLKSTLEVSKQGKLSNGCPYFATRKSVPQCQLVLLPYQVLLHDGTRKAWGIELKDNVIVLDEAHNVLNTISSLYSAEISTKSLTLALRLIREYNAHYKLKLLAHNLLYMKQLESLTSKMLIFLNSQ-SKEDVMTMAQLARNLNILEINLFKLAEYMEKTDLCKKFHGFYMRLQKEEIKKE--NEKPKLTGIQKLMAAKEAEPEPEAEPLPPPKPVPSPLFSLKSFIDALTNKCEDGRIIVEKSATEAKFRFMLLNPADRLSEVVTSARATILVGGTMEPAQLLVETLSRGS-IGADSIRRFSCCHVIDDSQLLAV-TVERTVDGKPFQLTYQTRGADTTLRSLATSIQALIPHIPNGVVIFVPSYDFLFNFQKKMKEFGILKRIEEKKAVFTESRQPTSD------------------VWDRFSRAAKTSKGAILFAVVGGKMSEGINFCDELGRAVIVIGLPYPNKTSVELRERMKFLDTQMPN-GGNLLYESLCMHAVNQAIGRAIRHRRDYAAVYLFDDRYA-----KESTRRK----LSTWIGDRTQVKLGFGEIIRKTRSFFE 825          

Query:  451 ESNEENFVV-NYNSDEE--VSND-----IENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKP-IGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQM-----------DSEKATDELGNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYG-----SESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            ES EE  V+  Y SDEE  V++       E+   E  ITKIY+CSRTHSQL Q + E+ K+ +   +     GSRQNLC+N  V  L S+ LIN++C+D+Q+    K     E   K+R+    A C F ++E++  +    +    D+EQL+  G ++  CP+Y  + +   A LV++PYQ +L+ A R A+ I ++D +VI DEAHNL DTI+ ++SV++  S L     QL  Y+ +Y +R  +KNL+YL+Q+  +    +  +   I    +  SLS          +FLF++ ++ + L ++  + +KS ++ KL             V   R+   L G  Q ++  Q            +S+ +  +  + ++ +  F+AA+  +  D  +++ +   L+     FL+++P  +   +V +CR++++ GGTMQP SDF  +L   A   ++R+  FSC HVI       V+  G++  N PL FTF+ R+   M+   G I  ++      GVV FFSSY  + ++   W+  G+L  +   K ++ EPK + Q E V+  +++          ++           A+L +V+G KMSEGINFSD L R V++VG+P+P  RS  LQEKM+Y+++        +   + +  NL MK VNQ+IGRAIRH+ DFA+I+LLD+RYA    +++         LP+W++ SV ++      I+ ++ F +
Sbjct:  191 ESGEEELVLAEYESDEEKKVASGHRVDEDEDDLEEEHITKIYHCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVRSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYRSRLAIPAAKLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTITGMHSVEVSGSQLCQAHSQLLQYMERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGA----VFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASVPQPASPLMHIEGFLAALTTANQDGRVILSRQGSLSESTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSCGHVIPPDNIPLVICSGIS--NQPLEFTFQKRDLPQMMDEVGRILCNLCGVVSGGVVCFFSSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSR---------CIQACGQERGQVTEALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFASIVLLDQRYARPPVLAK---------LPAWIRASVEVKATFGPAIAAVQKFHR 901          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
            F FP+ PY  Q   M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL
Sbjct:   13 FPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWL 62          

Query:  451 ESNEENFVV-NYNSDEE--VSNDIENQENEGS---ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKP-IGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---DSYSSLSCV--------EFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQM-----------DSEKATDELGNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMK-VMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYG-----SESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELK----SFF 2526
            ES EE  V+  Y SDEE  V++ ++  E++     ITKIY+CSRTHSQL Q + E+ K+ +   +     GSRQNLC+N  V  L S+ LIN +C+D+Q+    K     E   K+R+    A C F ++E++  +    +    D+EQL+  G ++  CP+YG + +   A LV++PYQ +L+ A R A+ I ++D +VI DEAHNL DT + ++SV++  S L     QL  Y+ +Y +R  +KNL+YL+Q+  +    +  +   I    +  SLS          +FLF++ ++ + L ++  + +KS ++ KL             V   R+   L G  Q ++  Q            +S+ +  +  + ++ +  F+AA+  +  D  +++ +   L+     FL+++P  +   +V +CR++++ GGTMQP S+F  +L   A   ++R+  FSC HVI     +  V+  GV+  N PL FTF+ R+   M+   G I  ++      GVV FF SY  + ++   W+  G+L  +   K ++ EPK + Q E V+  +++          ++          GA+L +V+G KMSEGINFSD L R V++VG+P+P  RS  LQEKM+Y+++        +   + +  NL MK VNQ+IGRAIRH+ DFA+I+LLD+RYA    +++         LP+W++  V ++      I+ ++    +FF
Sbjct:  210 ESGEEELVLAEYESDEEKKVASGVDEDEDDLEEEHITKIYHCSRTHSQLAQFVHEVKKSPFGKDVRLVSLGSRQNLCVNEDVRSLGSVQLINNRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRLQDQVVIIDEAHNLIDTTTSMHSVEVSGSQLCQAHSQLLQYMERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGMELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGA----VFSSREQPKLAGFQQFLQSLQPRTTEALAAPADESQASVPQPASPLMHIEGFLAALTTANQDGRVILSRQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAGGTMQPVSNFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGVS--NQPLEFTFQKRDLPQMMDEVGRILCNLCGVVSGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSR---------CLQACGQERGPVTGALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAHPGKALVENLCMKAVNQSIGRAIRHQKDFASIVLLDQRYARPPVLAK---------LPAWIRARVEVKATFGPAIAAVQKVSPTFF 922          

Query:   85 LMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
             M+ELY  +E  KIGIFESPTGTGKSLS++C +L+WL
Sbjct:   45 FMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWL 81          

Query:   28 SNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIK------------------NKLEIKQIEDDSQ----NDFDWINAYAQSKKSKL---NLTDQ------NEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQ---------ESNEENFVV-NYNSDEEVS-------NDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI----------DSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVV---------VRPRQSSALFGGNQLIKENQMDSEKATDE---LGNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
             N    F FP++PYP Q + M  LYA +E+ K+GIFESPTGTGKSLS++C +L WL   +E +  E  K                  + + +++ E  S      + DW++ + Q +  +     L D+       ED  +      Q+K    +K S N+ T K    S Q         E +E+  VV +Y SDEEV+       +D ++   E  +TKIYYCSRTHSQL Q + E+ K+ Y+  ++    GSRQNLCIN  V +L S+ LIN++C++LQK         ++  K+R+    A C+F  YEK+  +   ++    DIEQLV  G  +  CP+Y  + +   A +V++PYQ++L+ A R AS I++KD IVI DEAHNL DTI+ ++S ++  + L     QL  Y  +Y  R  +KNL+Y++Q+  +   L+  +  K+               L+  +FLF+  ++ + L ++  + +KS ++ KL       E   V            R         G Q      ++ + + ++   + + M+ V +F+ A+  +  D  +++EK   L      FL+++   +   ++ +CR++++ GGTMQP SDF  +L  +A  P++RI  FSC HVI  +  + ++ L        L FTF+ R+   M++ TG +  ++ +  P GVV FF SY    +I+  W+S GVL  +   K ++ EPK++ Q E V++ ++K          ++    +  S  GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  +SP LQEKM+Y++K      G    + +  NL MK VNQ+IGRAIRH+ D+A I+L D RYA          R G L  LP W++ S S  +N     + ++ FF
Sbjct:    4 GNGVSRFPFPFKPYPIQERFMEALYAVLEQGKVGIFESPTGTGKSLSLICGALTWLKDCEEKKRQEAAKLLEHTVSARAVGGGGKDGDGITVQEEEKGSSAGADGELDWVSEFVQKRAEREMVNKLKDEEVKRKRREDRLEMIRHNAQLKYSMKRKNSENSETEKLLQCSKQDAGSEEGPNEDDEDGLVVADYESDEEVTPKNRLCDDDDDDDLEEEHVTKIYYCSRTHSQLAQFVHEVQKSPYSSTVSLVNLGSRQNLCINPEVARLGSVQLINDRCMELQKNKHDKQNKVDSEPKRRRGAIKATCAFSGYEKMMTMRDEVLASVRDIEQLVQHGRDTHTCPYYSTRLAIPAAQVVVLPYQSLLHAATRKASGIKLKDQIVIIDEAHNLTDTITALHSAEVNGAQLCRAHSQLSQYCDRYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVGLNPVTQTTQSGTELLTINDFLFRAQIDNINLFKVQRYFEKSLISRKLFGFSEKYEGSGVSTHTSSMNKENHRTEGLGRFLQGLQSKATAPVEPQGSVEDRPIMASPMMLVESFLFALTSANKDGRVVMEKQACLAQSSVKFLMLNAAVHFAQVLQECRAVVIAGGTMQPVSDFKEQLLLSAGVPNERIVEFSCGHVIPPENILPII-LCTGPSGQELEFTFQTRDTPQMMEETGRVLSNLCNVVPGGVVCFFPSYEYERRILGHWESNGVLQRLAAKKKIFQEPKKASQVEQVLSEYSK---------CIQRCINTGGSQSGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKHMPLVDGRSPGKALIENLCMKAVNQSIGRAIRHRGDYACIVLCDRRYA----------RTGTLQKLPEWIRSSTSTHSNFGPAFASIRKFF 897          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL-------------LVNQ----------ENQMNELIKNKLEIKQIEDDSQNDFDWINAYAQSKKSKL---NLTDQ------NEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEEN----------FVVNYNSDEEVSNDIENQE--------NEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKID----SYSSLSCVE------FLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIK----------------ENQMDSEKATDELGNAMLTVRNFIAAVYYS-LDASILVEKDV-----GLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
            F FP++PYP Q + M  LYA +E+RK+GIFESPTGTGKSLS++C +L WL             L+            EN  N + K+  E ++    +  + DW++ + Q +  +     L D+       E+  +      Q+K    +K S  N   K    S QE + E            V +Y SDEEV+    N +         E  ITKIYYCSRTHSQL Q + E+ K+ Y   ++    GSRQN+C+N  V +L S+ LIN++C++LQK         +   K+R+    A C+F  YEK+  +   ++    DIEQL+  G ++  CP+Y  + +   A +V++PYQ++L+ A R AS I++KD IVI DEAHNL DT++ ++S ++  + L     QL  Y  +Y  R  +KNL+Y++Q+  +   L+  +  K+     + S+ S  E      FLF+  ++ + L ++  + +KS ++ KL   +   E   V       SS++   NQ I+                  Q  + +    + + M+ V +F+ A+  S  D  ++++K        L FL+++   +   +V +CR++I+ GGTMQP +DF  +L  +A    +RI  FSC HVI  +  + ++ L        L FTF+ R+   M++ TG +  ++ +  P GVV FF SY    +I+  W+S GVL  +   K V+ EPK++ Q E V++ +++          ++  +++ +   GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  +SP LQEKM+Y++K      G    + +  NL MK VNQ+IGRAIRH+ D+A I+L D RY+          R G L  LP W++ S    ++     + ++ FF
Sbjct:   10 FPFPFKPYPIQERFMEALYAALEQRKVGIFESPTGTGKSLSLICGALTWLRDFEEKKREEAATLLQHSERDRKGGGGENVCNGVQKSGQEEERGSSGATTEPDWVSEFVQKRAEREMVNKLKDEEMKRKRREERLEMIRHNAQLKYAMKRKSSEVNEVEKLLQLSKQELSSEEKSHEEEEEGLIVADYESDEEVTTKTRNCDDDDNDDDLEEEHITKIYYCSRTHSQLAQFVHEVQKSPYGSTVSLVNLGSRQNMCVNPDVARLGSLQLINDRCMELQKNKHDKQNKADLEPKRRRGVAKATCAFSGYEKLMAMRDEVLVKVRDIEQLLQHGRETHTCPYYSTRMAIPAAEVVVLPYQSLLHAATRKASGIKLKDQIVIIDEAHNLADTLTALHSAEVNGAQLCRAHSQLSQYCDRYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVGLNPVTQSTQSGAELLTINDFLFRAQIDNINLFKVQKYFEKSMISRKLCGFVEKYEGKGVNT----HSSSVNKENQRIEGLGRFLQSLQNKPAAPPEQQGAVEDRPSMASPMMLVESFLFALTNSNKDGRVVMDKQACLAQSSLKFLMLNAAVHFAQVVQECRAVIIAGGTMQPVADFKEQLLLSAGVSEERISEFSCGHVIPPENILPIV-LCAGPSGQELEFTFQTRDTPRMMEETGRVLSNLCNVVPGGVVCFFPSYEYEKRILGHWESNGVLQRLAAKKKVFQEPKKASQVEQVLSEYSR---------CIQRCSSTGQGQSGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKNMPHVDGRSPGKTLVENLCMKAVNQSIGRAIRHRGDYACIVLCDRRYS----------RTGTLQKLPEWIRSSTHTHSSFGPAFASIRRFF 899          

Query:   22 IMSNQFYA--------FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQN-----------------DFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQ---------ESNEEN-------------FVVNYNSDEE------VSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQK-PIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKID----------SYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIE-TGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGN--------------AMLTVRNFIAAVYYS-LDASILVEKDV-----GLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
            ++S QF+A        F FPYEPY  Q + M  LY TI++ KIGIFESPTGTGKSLS++C +L WL  ++E +  E +   LE + +  DS +                 + +WI  + Q KK++  L D+ ++   +K   ++   +      +        +   +         ES EE+              V +Y SD++      + ++ E+   E  +TKIYYCSRTHSQL Q + E+ K+ + +++      SRQNLCIN  V +L S+ LIN++C+++Q+   GK ++ T+T  K+R+    A C F  +E +  +    +    D+E +VV G ++  CP+YG + +   A LV++PYQ +L+ A R AS I++KD +VI DEAHNL DTI+ + S +++ + L     QL  Y+ +Y  R  +KNL+Y++Q+  +   L+  +  K+D              L+   FLF+  ++ + L ++  + +KS ++ KL   +   + TG  V V  +++    G  + +K  Q   +  T  +                 M+ V  F++A+  +  D  ++V++        L FL+++P  +   ++ +C+++I+ GGTMQP +DF  +L  +A    +RI  FSC HVI   Q +  + L        L FTF+NR    M++ TG +  ++ +  P G+V FF SY    +++  W S GVL  +   K ++ EP+++ Q E V+  +++          +++ + +     GA+LF+V+G KMSEGINFSDEL R VI+VG+PYP  +SP LQEKM+Y++K      G    + +  NL MK VNQ+IGRAIRH+ D+A I+LLD RY+          R G L  LP W+++   +Q         ++ FF
Sbjct:    5 VLSLQFHAGMETTTLQFPFPYEPYSIQKQFMEALYTTIDEGKIGIFESPTGTGKSLSLICGALTWLRDHEEKKKQEAV-GLLEERDVTMDSSSTQPPQGHCSSPALSSSTEPNWIADFVQ-KKAERELVDKLKEEAIRKRKREERMELIRHNVQLQYALKHKSDQDEEARRLLRLSAESGEEDGKGAVLGDGEEELIVADYESDDDGKPKNSICDEEEDDLEEDHVTKIYYCSRTHSQLAQFVHEVQKSPFREEVRVVSLASRQNLCINEEVRRLGSVQLINDRCMEMQRNKHGKAEKSTDTEPKRRRREPKAVCPFSRHEALLGLRDETLVKVRDVEDMVVLGRETKACPYYGGRLAVPAAQLVVLPYQVLLHEAMRRASGIKLKDQVVIIDEAHNLMDTIACIYSSEVMGTQLCCAHSQLTQYMERYRNRLKAKNLMYVKQILFVLEGLVHVLGGKVDQNPHSQVTQAGTEMLTINNFLFRAQIDNINLFKVQRYFEKSLISRKLNGFVEKYQGTGVAVSVSKKENQRTEGLGRFLKSLQSGQQAHTVPIPGQKVAEEDKQSSVVCPMIQVEGFLSALTNANKDGRLVVQRQGTLAQDSLKFLLLNPAIHFAPVLKECKAVIIAGGTMQPVADFKEQLLLSAGVSEERISGFSCGHVI-PPQNILPIVLCSGPSGQELEFTFQNRETPQMMEETGRVLSNLCNVVPGGLVCFFPSYEYERRVLAHWNSTGVLGRLAARKKIFQEPRKASQVEQVLKEYSR---------CIQHCSQAGAVLSGALLFSVVGGKMSEGINFSDELGRCVIMVGMPYPNIKSPELQEKMAYLDKHMPHVGGQSPGKALVENLCMKAVNQSIGRAIRHRGDYACIVLLDRRYS----------RPGTLQKLPEWIRNRTQVQPTFGPAFGGIRKFF 907          

Query:   22 IMSNQFYA--------FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQN-----------------DFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQ---------ESNEEN-------------FVVNYNSDEE------VSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQK-PIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKID----------SYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
            ++S QF+A        F FPYEPY  Q + M  LY TI++ KIGIFESPTGTGKSLS++C +L WL  ++E +  E +   LE + +  DS +                 + +WI  + Q KK++  L D+ ++   +K   ++   +      +        +   +         ES EE+              V +Y SD++      + ++ E+   E  +TKIYYCSRTHSQL Q + E+ K+ + +++      SRQNLCIN  V +L S+ LIN++C+++Q+   GK ++ T+T  K+R+    A C F  +E +  +    +    D+E +VV G ++  CP+YG + +   A LV++PYQ +L+ A R AS I++KD +VI DEAHNL DTI+ + S +++ + L     QL  Y+ +Y  R  +KNL+Y++Q+  +   L+  +  K+D              L+   FLF+  ++ + L ++  + +KS ++ KL   +   +   V V   +            KENQ      T+ LG        F+ ++     A         L FL+++P  +   ++ +C+++I+ GGTMQP +DF  +L  +A    +RI  FSC HVI   Q +  + L        L FTF+NR    M++ TG +  ++ +  P G+V FF SY    +++  W S GVL  +   K ++ EP+++ Q E V+  +++          +++ + +     GA+LF+V+G KMSEGINFSDEL R VI+VG+PYP  +SP LQEKM+Y++K      G    + +  NL MK VNQ+IGRAIRH+ D+A I+LLD RY+          R G L  LP W+++   +Q         ++ FF
Sbjct:    5 VLSLQFHAGMETTTLQFPFPYEPYSIQKQFMEALYTTIDEGKIGIFESPTGTGKSLSLICGALTWLRDHEEKKKQEAV-GLLEERDVTMDSSSTQPPQGHCSSPALSSSTEPNWIADFVQ-KKAERELVDKLKEEAIRKRKREERMELIRHNVQLQYALKHKSDQDEEARRLLRLSAESGEEDGKGAVLGDGEEELIVADYESDDDGKPKNSICDEEEDDLEEDHVTKIYYCSRTHSQLAQFVHEVQKSPFREEVRVVSLASRQNLCINEEVRRLGSVQLINDRCMEMQRNKHGKAEKSTDTEPKRRRREPKAVCPFSRHEALLGLRDETLVKVRDVEDMVVLGRETKACPYYGGRLAVPAAQLVVLPYQVLLHEAMRRASGIKLKDQVVIIDEAHNLMDTIACIYSSEVMGTQLCCAHSQLTQYMERYRNRLKAKNLMYVKQILFVLEGLVHVLGGKVDQNPHSQVTQAGTEMLTINNFLFRAQIDNINLFKVQRYFEKSLISRKLNGFVEKYQGTGVAVSVSK------------KENQR-----TEGLG-------RFLKSLQSGQQAHTGTLAQDSLKFLLLNPAIHFAPVLKECKAVIIAGGTMQPVADFKEQLLLSAGVSEERISGFSCGHVI-PPQNILPIVLCSGPSGQELEFTFQNRETPQMMEETGRVLSNLCNVVPGGLVCFFPSYEYERRVLAHWNSTGVLGRLAARKKIFQEPRKASQVEQVLKEYSR---------CIQHCSQAGAVLSGALLFSVVGGKMSEGINFSDELGRCVIMVGMPYPNIKSPELQEKMAYLDKHMPHVGGQSPGKALVENLCMKAVNQSIGRAIRHRGDYACIVLLDRRYS----------RPGTLQKLPEWIRNRTQVQPTFGPAFGGIRKFF 862          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNE---LIKNKLEIKQI-------------EDDSQN------DFDWINAYAQSKKSKL---NLTDQ------NEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEEN----------FVVNYNSDEEVS--------NDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKID----SYSSLSCVE------FLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRP------RQSSALFGGNQLIKENQ------MDSEKATDELGNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
            F FP++PYP Q + M  LY  +E+ K+GIFESPTGTGKSLS++C +L WL   +E +  E   L+++ +    +             E++  N      + DW++ + Q +  +     L D+       ED  +      Q+K    +K S N+ T K   +S +++  E+           V +Y SDEE +         + ++   E  +TKIYYCSRTHSQL Q + E+ K+ Y   ++    GSRQNLCIN  V +L S+ LIN++C++LQK         ++  K+R+    A C+F  YEK+  +   ++    DIEQLV  G  +  CP+Y  + +   A +V++PYQ++L+ A R AS I++KD IVI DEAHNL DTI+ ++S ++  + L     QL  Y  +Y  R  +KNL+Y++Q+  +   L+  +  K+     + S+ S  E      FLF+  ++ + L ++  +++KS ++ KL       E   V           R++  L    Q ++           SE+    + + M+ V +F+ A+  +  D  +++EK   L      FL+++   +   ++ +CR++++ GGTMQP SDF  +L  +A    +RI  FSC HVI  +  + ++ L        L FTF+ R+   M++ TG +  ++ +  P GVV FF SY    +I+  W+S GVL  +   K ++ EPK++ Q E V++ +++          ++  + +     GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  +SP LQEKM+Y++K      G    + +  NL MK VNQ+IGRAIRH++D+A I+L D RYA          R G L  LP W++ S    +N     + ++ FF
Sbjct:   10 FPFPFKPYPIQERFMEALYTVLEEGKVGIFESPTGTGKSLSLICGALTWLKDFEEKKRQEAEKLLEHTVSASAVGGGGKNGDGITVREEEKSNSAGVDGELDWVSEFVQKRAERELVNKLKDEEMKRKRREDRLEMIRHNAQLKYTMKRKNSENSETEKLLQFSKKDAGSEDGPDEDEEDGLVVADYESDEETTPKNRLCDEEEDDDDLEEEHVTKIYYCSRTHSQLAQFVHEVQKSPYNSTVSLVNLGSRQNLCINPEVARLGSVQLINDRCMELQKNKHDKQDKVDSEPKRRRGAVKATCAFSGYEKMMTMRDEVLASVRDIEQLVQHGRDTHTCPYYSTRLAIPAAQVVVLPYQSLLHAATRKASGIKLKDQIVIIDEAHNLGDTITALHSSEVNGAQLCRAHSQLSQYCERYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVGLNPVTQSTQSGTELLTINDFLFRAQIDNINLFKVQRYLEKSLISRKLFGFSEKYEGSGVSTHTSSMNKENRRTEGLGRFLQGLQSKATAPVEYQGSEEDRPIMASPMMLVESFLFALSSANKDGRVVMEKQTCLAQSSVKFLMLNAAVHFAQVLQECRAVVIAGGTMQPVSDFKEQLLLSAGAHKERIAEFSCGHVIPPENILPII-LCTGPSGQELEFTFQTRDRPQMMEETGRVLSNLCNVVPGGVVCFFPSYEYERRILGHWESNGVLQRLAAKKKIFQEPKKASQVERVLSEYSR---------CIQRCSNTGGGQSGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKHMPHVDGRSPGKALIENLCMKAVNQSIGRAIRHRDDYACIVLCDRRYA----------RTGTLQKLPEWIRSSTRTHSNFGPAFAGIRKFF 898          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNE----LIKNKLEIKQIEDDSQNDF--------------DWINAYAQSKKSKL---NLTDQ------NEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEEN----------FVVNYNSDEEVS-------NDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKID----------SYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDV------VVVRPRQSSALFGGNQLIKENQMDSEKAT------DELGNAMLTVRNFIAAVYYS-LDASILVEKDV-----GLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKL-GLPSWLKDSVSIQNNTNSLISELKSFF 2526
            F FP++PY  Q + M  LYA +E+ K+GIFESPTGTGKSLS++C +L WL  ++E +  E    L + ++E K   D  + D               DW++ + Q +  +     L D+       E+  +      Q+K    +K + +N   K    S QE + E            V +Y SD+E +        D ++   E  +TKIYYCSRTHSQL Q + E+ K+ Y   ++    GSRQNLC+N  V +L S+ LIN++C++LQK        T+   K+R+    A C F  YEK+  +   ++    DIEQLV  G  +  CP+Y  + +   A +V++PYQ +L+ A R AS I++KD IV+ DEAHNL DTI+ ++S ++  + L     QL  Y  +Y  R  +KNL+Y++Q+  +   L+  +  K+               L+  +FLF+  ++ + L ++  + +KS ++ KL   +   E   V      V    R +  L    Q ++     + +          + + M+ V +F+ A+  S  D  ++++K        L FL+++   +   +V +CR++I+ GGTMQP +DF  +L  +A    +RI  FSC HVI  +  + ++ L        L FTF+ R+   M++ TG +  ++ +  P GVV FF SY    +I+  W+  G+L  +   K V+ EPK++ Q E V++ ++K          ++  + +     GA+LF+V+G KMSEGINFSD+L R +++VG+PYP  +SP LQEKM+Y++K      G    + +  NL MK VNQ+IGRAIRH+ D+A I+L D RY+          R G L  LP W++ S    ++     + ++ FF
Sbjct:   10 FPFPFKPYTIQERFMESLYAALEQGKVGIFESPTGTGKSLSLICGALTWLRDHEEKKKEEAARLLQEKEVERKGDGDGGEKDCNGDKSGGSGAATEPDWVSDFVQKRAEREIVNKLKDEEIKRKRREERLEMIRHNAQLKYAMKRKTNEDNEAEKLLQLSKQELSSEEKSHEEEEEGLIVADYESDDEATPKPRICDEDDDDDLEEEHVTKIYYCSRTHSQLAQFVHEVQKSPYGSTVSLVNLGSRQNLCVNPDVTRLGSVQLINDRCMELQKNKHDKQSKTDLEPKRRRSIAKATCPFTGYEKMMAMRDEVLVKVRDIEQLVQHGRGTHTCPYYSTRLAIPAAQVVVLPYQTLLHAATRKASGIKLKDQIVVIDEAHNLTDTITALHSAEVNGAQLCRAHSQLSQYCERYRSRLKAKNLMYIKQILFVLEGLVRTLGGKVSLNPVTQSTQPGTELLTINDFLFRAQIDNINLFKVQKYFEKSMISRKLCGFVEKYEGNGVNTHSNSVNKENRNTEGLGRFLQSLQNKPAAAAEQQAAVDDRPSMSSPMMLVESFLFALTNSNKDGRVVMDKQAYLSQSSLKFLMLNAAVHFAQVVQECRAVIIAGGTMQPVADFKEQLLLSAGLSEERIAEFSCGHVIPPENILPIV-LCAGPSGQGLEFTFQTRDTPQMMEETGRVLSNLCNVVPGGVVCFFPSYEYEKRILGHWEKTGILQRLAAKKKVFQEPKKASQVEQVLSEYSK---------CIQRCSNTGGGQTGALLFSVVGGKMSEGINFSDDLGRCIVMVGMPYPNIKSPELQEKMAYLDKNMPHIDGRSPGKALIENLCMKAVNQSIGRAIRHRGDYACIVLCDRRYS----------RSGTLQKLPQWIRSSTHTHSSFGPAFASIRKFF 893          

Query:  538 ITKIYYCSRTHSQLNQVLQELLK--------TSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPM-----DIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISD---VNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEF-----VSRKIDSY--------------------SSLSCVEFL--FKTYLN-EMKLDRILN--------------FIDKSKL---AYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVS 2478
            +TK+ YCSRT  ++ +V++EL K        T   +        SR+NLCI+  V+ L+    ++ KC  L          +   A+     +   C F  YE+ + V + +   P+     +++ L   G K G CP+Y  + S   A++V+  Y  +L+P  A L SK   K ++V+FDEAHN+ +   D   VN  +  L    T +  L++ I    QR    +   LR+    +  L+E      V+R+ D Y                    ++   V FL  F  YL   +++  ++                ID+  L   A +LR+ +R +E  D+    P    + F    L+           +   +   T+ N +                  L F  +DP   +K +  + +S+++  GT+ P  D   R+         R  T +   +  A+  +  + +G  +  V +   FE R + A+I+  G++ L + +  P+G+V FF+SY  M+ I+  W  +G+L  I++ K ++IE   + +                    +  +  + ++ +GA+L +V   K+SEGI+F     R VI+ G+PY  T+S IL+ ++ Y+  Q+    +  +  + AM+   Q +GRAIR K D+  +I  D+RYA   K       +GK  LP W+++ +S
Sbjct:   43 VTKLIYCSRTVPEIEKVVEELRKLMEFYTKETGEKNNFLALALSSRKNLCIHPEVSSLRFGKEVDGKCHSLTA--------SYIRAQHHSNPSQPVCRF--YEEFDAVGRQV---PIPSGIYNLDDLKDFGRKKGWCPYYLARYSILHANIVVYSYHYLLDPKIADLVSKELAKKSVVVFDEAHNIDNVCIDSMSVNITRRTLDRCQTNVDTLQNTI----QRIKETDAAKLREE---YRRLVEGLKEANVARETDIYLSNPVLPDEVLQEAIPGSIRTAEHFVGFLKRFLEYLKARLRIHHVVQESSPQFLKDIYEKVCIDRKPLRFCAERLRSLLRTLEIADIADFSPITLISHFA--TLVSTYSKGFTIIIEPFEDKTPTIANPV------------------LHFSCMDPSIAIKPVFERFQSVVITSGTLSPL-DIYPRILDF------RPVTMASFTMTLARTCLCPLIVGRGNDQVAMSSKFETREDFAVIRNYGNLLLEMSAIVPDGIVAFFTSYVYMENIVASWYEQGILENIQRNKLIFIETPDAAETSMA----------------LEKYQEACENGRGAILLSVARGKVSEGIDFVHHFGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGLMIFADKRYARADK-------RGK--LPRWIQEHIS 678          

Query:  538 ITKIYYCSRTHSQLNQVLQELLK--------TSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPM-----DIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISD---VNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEF-----VSRKIDSY--------------------SSLSCVEFL--FKTYLN-EMKLDRILN--------------FIDKSKL---AYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVS 2478
            +TK+ YCSRT  ++ +V++EL K        T   +        SR+NLCI+  V+ L+    ++ KC  L          +   A+     +   C F  YE+ + V + +   P+     +++ L   G K G CP+Y  + S   A++V+  Y  +L+P  A L SK   K ++V+FDEAHN+ +   D   VN  +  L    T +  L++ I    QR    +   LR+    +  L+E      V+R+ D Y                    ++   V FL  F  YL   +++  ++                ID+  L   A +LR+ +R +E  D+    P    + F    L+           +   +   T+ N +                  L F  +DP   +K +  + +S+++  GT+ P  D   R+         R  T +   +  A+  +  + +G  +  V +   FE R + A+I+  G++ L + +  P+G+V FF+SY  M+ I+  W  +G+L  I++ K ++IE   + +                    +  +  + ++ +GA+L +V   K+SEGI+F     R VI+ G+PY  T+S IL+ ++ Y+  Q+    +  +  + AM+   Q +GRAIR K D+  +I  D+RYA   K       +GK  LP W+++ +S
Sbjct:   67 VTKLIYCSRTVPEIEKVVEELRKLMEFYTKETGEKNNFLALALSSRKNLCIHPEVSSLRFGKEVDGKCHSLTA--------SYIRAQHHSNPSQPVCRF--YEEFDAVGRQV---PIPSGIYNLDDLKDFGRKKGWCPYYLARYSILHANIVVYSYHYLLDPKIADLVSKELAKKSVVVFDEAHNIDNVCIDSMSVNITRRTLDRCQTNVDTLQNTI----QRIKETDAAKLREE---YRRLVEGLKEANVARETDIYLSNPVLPDEVLQEAIPGSIRTAEHFVGFLKRFLEYLKARLRIHHVVQESSPQFLKDIYEKVCIDRKPLRFCAERLRSLLRTLEIADIADFSPITLISHFA--TLVSTYSKGFTIIIEPFEDKTPTIANPV------------------LHFSCMDPSIAIKPVFERFQSVVITSGTLSPL-DIYPRILDF------RPVTMASFTMTLARTCLCPLIVGRGNDQVAMSSKFETREDFAVIRNYGNLLLEMSAIVPDGIVAFFTSYVYMENIVASWYEQGILENIQRNKLIFIETPDAAETSMA----------------LEKYQEACENGRGAILLSVARGKVSEGIDFVHHFGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGLMIFADKRYARADK-------RGK--LPRWIQEHIS 702          

Query:  973 MLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISD---VNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEF-----VSRKIDSY--------------------SSLSCVEFL--FKTYLN-EMKLDRILN--------------FIDKSKL---AYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVS 2478
            +L+P  A L SK   K ++V+FDEAHN+ +   D   VN  +  L    T +  L++ I    QR    +   LR+    +  L+E      V+R+ D Y                    ++   V FL  F  YL   +++  ++                ID+  L   A +LR+ +R +E  D+    P    + F    L+           +   +   T+ N +                  L F  +DP   +K +  + +S+++  GT+ P  D   R+         R  T +   +  A+  +  + +G  +  V +   FE R + A+I+  G++ L + +  P+G+V FF+SY  M+ I+  W  +G+L  I++ K ++IE   + +                    +  +  + ++ +GA+L +V   K+SEGI+F     R VI+ G+PY  T+S IL+ ++ Y+  Q+    +  +  + AM+   Q +GRAIR K D+  +I  D+RYA   K       +GK  LP W+++ +S
Sbjct:  117 LLDPKIADLVSKELAKKSVVVFDEAHNIDNVCIDSMSVNITRRTLDRCQTNVDTLQNTI----QRIKETDAAKLREE---YRRLVEGLKEANVARETDIYLSNPVLPDEVLQEAIPGSIRTAEHFVGFLKRFLEYLKARLRIHHVVQESSPQFLKDIYEKVCIDRKPLRFCAERLRSLLRTLEIADIADFSPITLISHFA--TLVSTYSKGFTIIIEPFEDKTPTIANPV------------------LHFSCMDPSIAIKPVFERFQSVVITSGTLSPL-DIYPRILDF------RPVTMASFTMTLARTCLCPLIVGRGNDQVAMSSKFETREDFAVIRNYGNLLLEMSAIVPDGIVAFFTSYVYMENIVASWYEQGILENIQRNKLIFIETPDAAETSMA----------------LEKYQEACENGRGAILLSVARGKVSEGIDFVHHFGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGLMIFADKRYARADK-------RGK--LPRWIQEHIS 607          

Query: 1570 LTFLVVDPGKYLKDIVNQ-CRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCE--HVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRI-------MYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            L++    PG  +++++ Q  R +I+  GT+ P S F+        C        S E  HVI  K Q+ V  +      V L   F+ R     + + G+  +++    P+G+++FF SY V+DK +E W++ G    I+ +K +++EP+       VI  F  +                 KSN G+  FAV   K SEG++F+D   R VII G+P+P    P +  KM Y+++   ++SS +        Y   A + VNQAIGR IRH+ D+ AI L D R+ +    ++         LPSW++  V + +N  +++ +   FF+
Sbjct:  452 LSYWCFCPGFSMQELLRQEVRCIILTSGTLSPLSSFT--------CEMQIPFPVSLENPHVIQ-KDQIFVSIVDKGPDGVQLSTAFDKRFVPENMASLGNTIVNLSRVVPHGLLVFFPSYPVLDKTLEFWRANGHADRIENMKPMFVEPRGKGTFTEVIDGFYDK-------------VNDPKSNGGS-FFAVCRGKASEGLDFADTYGRGVIITGLPFPPRMDPRVVLKMQYLDEMCRNKSSGMKYLSGQEWYRQQASRAVNQAIGRVIRHREDYGAIFLCDHRFKNTDVRAQ---------LPSWVRPYVRM-DNFGTVVRDAAQFFR 748          

Query:  538 ITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRK 1143
            I KI Y SRTHSQL QV+ EL  T+Y  K+  C  GSR+ LCIN  + + +S ++    C                   + KV+T +C  + + ++ +   K+I+   +D+E LV  G K   CP+Y  +     A L+ MPY  +L+P +R A  IE+K  +VIFDEAHN+     +  S  L    L + +  +   +R+
Sbjct:  106 IPKIIYASRTHSQLTQVVSELKNTAYRPKV--CVLGSREQLCINQEIMKQESNHIKVHMC-------------------RAKVSTRSCLFYNNVDE-KSTDKDIMNSILDVEDLVKTGKKERVCPYYLSRSLKQHADLIFMPYNYLLDPKSRRAHNIELKGAVVIFDEAHNVEKMCEESTSFDLTPYDLTSAIDAVDKLLRE 285          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
            +FP+ PYP Q   M+++   ++ +  G+ ESPTGTGK+L +LC++L W
Sbjct:   12 DFPFTPYPCQTDYMNKVIECLQSKVNGVLESPTGTGKTLCLLCATLGW 59          

Query:  538 ITKIYYCSRTHSQLNQVLQELLK--------TSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGAC--CSFKSYEKIEEVSKNIIRHP--MDIEQLVVAGLKSGGCPFYGIKKS-FNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISD---VNSVKLLLSHLVTGLK---------------QLKSYIRKYLQRFSSKNLL---------------YLRQLETIFSN------LIEFVSR---------KIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAY---KLRNSMRNIETGDVVVVRPRQSSALFG--------GNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMI-VIGGTMQPFSDFS----NRLFKNAECPSDRIH-TFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQN 2487
            + K+ YCSRT  ++ +V++E+ K        T    K       SR+NLCI+  V+ L+    ++ +C  L          T +  + R  + G+   CSF  YE      + +   P    ++ L   G +   CP++  + S    A++V+  Y  +L+P  A L SK   K ++V+FDEAHN+ +   D   VN  +  L    T ++               +LK   R+ ++     ++                 L+  E +  N       + F+ R         ++    S S   FL +TY      DRI   ID+  L +   +LR+ +R +E  D+    P      F         G  LI E     E  T  + N +L  R       +S +  + V                   +VN  R+ + V  GT    + F     N  F    C +  +  TFS     N    MK++  G  +  V +   FE R + A+I+  G++ L +    P+GVV FF+SY+ M+ I+  W  +G+L  I++ K ++IE +     E  +A              +  +  + ++ +GAVL +V   K+SEGI+F     R VI+ GIPY  T+S IL+ ++ ++   Y    +  +  + AM+   Q +GRAIR K D+  ++  D+RY+   K       +GK  LP W+++ ++  N
Sbjct:   33 VQKLVYCSRTVPEIEKVIEEMKKLVAYYEKHTKEPMKFLALSLSSRKNLCIHPEVSALRFGKEVDGRCHSL----------TASYVRNRHSSDGSVPVCSF--YEDFNTNGREVPMPPGIYSLDDLKEYGRQKHWCPYFLARYSQIMHANVVVYSYHYLLDPKIADLVSKEMSKKSVVVFDEAHNIDNVCIDSMSVNITRRTLDRCSTNIETLQTTIQKIRETDATKLKEEYRRLVEGLRDASVARETDVHLANPVLPDEVLQDAEAVPGNSRNAEHFVSFLKRFVEYLKSRLRVTHVLSESTPAFLKETY------DRIC--IDRKPLRFCSERLRSLLRTLEIADIADFSPLTLVCNFATLVSTYTNGFTLIIE---PFEDKTPTILNPILRFRR------HSKNQKLSVH------------------MVNDTRASVNVPCGTRALLNRFPLDKVNTRFTALRCITGVLALTFS----PNRGLAMKIVARG--NDQVTMSSKFETREDIAVIRNYGNLLLEMTCVVPDGVVCFFTSYHYMESIVAAWYEQGILENIQRNKLIFIETQDG--AETSVA--------------LEKYHEACENGRGAVLLSVARGKVSEGIDFVHHYGRAVIMFGIPYVYTQSRILKARLEFLRDHYQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGVMVFADKRYSRADK-------RGK--LPRWIQEHITDAN 682          

Query: 1738 HVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQ-SLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIM-----------YHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            HVI+ K Q+ V  +     +V L   + NR+  A + + G   +++    PNG+++FF SY VMD  ++ W+++G+ S+I+++K +++EPKQ  L  E +   + K          + +   SA     A  FAV   K+SEG++F+D   R VII G+P+P    P ++ KM ++++     S+ +            Y   A + VNQAIGR IRH++D+ AIIL D R++  + +++         LPSW++ SV       +++ EL  FF+
Sbjct:    9 HVID-KHQVWVGIVEKGPDSVQLNSAYRNRSCPAYMSSLGKTIVNLARIIPNGLLVFFPSYTVMDMCLQHWKNEGLSSKIEEIKPMFVEPKQKGLFTEAINGFYDK----------INDPRCSA-----AAFFAVCRGKVSEGLDFADANGRAVIITGLPFPPQMDPWIKLKMQFLDEMKAKRSTEMQCEFVGLSGQEWYTQQASRAVNQAIGRVIRHRHDYGAIILCDHRFSSASAVAQ---------LPSWMRPSVKAYPEFGAVVRELSQFFR 259          

Query:  532 GSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIR 1140
            G+I KI Y SRTHSQL+Q + EL   SY  ++  C  GSR+ LCI+  V + +S +     C                    R  TT   C +  Y  +EE   + I   MD+E+LV  G K   CP++  ++  + A ++ MPY  +L+  +R A  I++   IVIFDEAHN+     +  S  L    L + +  +  +++
Sbjct:   95 GNIPKIIYSSRTHSQLSQAMNELKNASYKPRV--CVLGSREQLCIHPDVVKQESNHAKVHLC--------------------RAKTTSRSCFY--YNNVEEKKTDFIAGIMDVEELVKKGKKHQVCPYFMTQELKHDADIIFMPYNYLLDTKSRRAHSIDLSGKIVIFDEAHNVERLCENAASFDLTPFELASSIDAVSHFLQ 273          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQ 273
            +FP+ PY  Q   M+++   +   K GI ESPTGTGK+L +LC++L W    +E+Q+ + ++ + +     DD +
Sbjct:   12 SFPFTPYKCQEDYMAQVIDCLNLGKNGILESPTGTGKTLCLLCATLAW----REHQVGQHVRQREQQNSWGDDGR 82          

Query:  532 GSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKS--INLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIE-----EVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHL------VTGLKQLKSYIRKYLQRFSSKNLLYLRQL 1191
            G+I KI Y SRTHSQL+Q + EL   SY  ++  C  GSR+ LCI+  V + +S    + N + + L                 R  TT   C +  Y  +E       S+ +    MD+E+LV  G K   CP++  ++  + A ++ MPY  +L+  +R A  I++   IVIFDEAHN+     +  S  L    L      V+   Q+KS  +  L   S +++  ++QL
Sbjct:   96 GNIPKIIYSSRTHSQLSQAMNELKNASYKPRV--CVLGSREQLCIHPDVVKQESNHAKVWNNRLVHL----------------CRAKTTSRSCFY--YNNVEVYCSLRASQRLAGRIMDVEELVKKGKKHQVCPYFMTQELKHDADIIFMPYNYLLDTKSRRAHSIDLSGKIVIFDEAHNVERLCENAASFDLTPFELASSIDAVSHFLQMKSRTQTVLHDVSIEDVANIKQL 308          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNK 240
            +FP+ PY  Q   M+++   +   K GI ESPTGTGK+L +LC++L W    +E+Q+ + ++ +
Sbjct:   12 SFPFTPYKCQEDYMAQVIDCLNLGKNGILESPTGTGKTLCLLCATLAW----REHQVGQHVRQR 71          

Query:  532 GSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHP--MDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIR 1140
            G+I KI Y SRTHSQL+Q + EL   SY  ++  C  GSR+ LCI+  V + +S +     C                   + K T+ +C  + + E   E + ++   P  MD+E+LV  G K   CP++  ++  + A ++ MPY  +L+  +R A  I++   IVIFDEAHN+     +  S  L    L + +  +  +++
Sbjct:   95 GNIPKIIYSSRTHSQLSQAMNELKNASYKPRV--CVLGSREQLCIHPDVVKQESNHAKVHLC-------------------RAKTTSRSCFYYNNVEG--ECAVHLTPTPGIMDVEELVKKGKKHQVCPYFMTQELKHDADIIFMPYNYLLDTKSRRAHSIDLSGKIVIFDEAHNVERLCENAASFDLTPFELASSIDAVSHFLQ 276          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQ 273
            +FP+ PY  Q   M+++   +   K GI ESPTGTGK+L +LC++L W    +E+Q+ + ++ + +     DD +
Sbjct:   12 SFPFTPYKCQEDYMAQVIDCLNLGKNGILESPTGTGKTLCLLCATLAW----REHQVGQHVRQREQQNSWGDDGR 82          

Query:   43 AFNFPYEPYPQQMKLMSELYATI-EKRKIGIFESPTGTGKSLSVLCSSLNW------------------------------------------------LLVNQENQMNELIKNKLEIKQIE-----DDSQNDFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVSNDIENQE-----NEGSITKIYYCSRTHSQLNQVLQEL----LKTSYADKIAT-----CCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPM------DIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYS-SLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVY-YSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVP-LRFTFENRNNEAMI-KATGDIFLSIFSFCP--NGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVE---------KQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFF 2526
             F  PY+PY  Q++LM  +Y  + E +KI I ESPTGTGK+LS++C+++ W                                                LL + E  +NE+  N    KQ++     D     +  ++   + +K   +L    E+ +      +         +S       D +Y   E N +   +    D +VS D  N +     N+  + KIYY SRT+SQL Q   +L      +S+ DK+           S++ LCIN  V + K++  IN+ C DL+                   +   C  +++  +       +    M      DIE LV  G   G CP+Y  +++   A +V +PYQ +L+ + R + +I ++++IVI DEAHNL +TI+ + S ++ L  L    K + +Y  K+  R +  N + L +L ++   LI+F+ +        +   +    + ++ + + ++L +I  SK+AYK+    +         ++  +SS        IKE    S  +       +  V  F+  +   + +     EK+  + +++++P K  + I+NQ + +++ GGTM+P S+F + L    E PS+ I T SC HVI  +     +T      N P L FTFE R + +++       F+ +    P   G+V FF SY  +  +I+ W+     + +  ++ ++ E K                       I+  ++ S    +G++L A++G K+SEGINF D+L R V++VG+P+P   S  L  K  ++          ++  S +++    N+ MK VNQ++GRAIRH ND+A I LLD RY      +    RK    L  W++DS++ ++ T+ +IS  + FF
Sbjct:    9 TFYHPYKPYDIQVQLMETVYRVLSEGKKIAILESPTGTGKTLSLICATMTWLRMNKADIFTRMETNIKTNEDDSENLSDDEPDWVIDTYRKSVLQEKVDLLNDYEKHLNEI--NTTSCKQLKTMCDLDKEHGRYKSVDPLRKKRKGARHLDVSLEEQDFIPRPYESDSENNDTSKSTRGGRISDKDYKLSELNSQIITLLDKIDGKVSRDPNNGDRFDVTNQNPV-KIYYASRTYSQLGQFTSQLRLPSFPSSFRDKVPDEKVKYLPLASKKQLCINPKVMKWKTLEAINDACADLRH------------------SKEGCIFYQNTNEWRHCPDTLALRDMIFSEIQDIEDLVPLGKSLGICPYYASREALPIAEVVTLPYQYLLSESTRSSLQINLENSIVIIDEAHNLIETINSIYSSQISLEDLKNCHKGIVTYFNKFKSRLNPGNRVNLLKLNSLLMTLIQFIVKNFKKIGQEIDPNDMFTGSNIDTLNIHKLLRYIKVSKIAYKIDTYNQ--------ALKEEESSK---NENPIKETHKKSVSSQP----LLFKVSQFLYCLTNLTSEGQFFFEKNYSIKYMLLEPSKPFESILNQAKCVVLAGGTMEPMSEFLSNLL--PEVPSEDITTLSCNHVIPKENLQTYIT------NQPELEFTFEKRMSPSLVNNHLFQFFVDLSKAVPKKGGIVAFFPSYQYLAHVIQCWKQNDRFATLNNVRKIFYEAKDGDD-------------------ILSGYSDSVAEGRGSLLLAIVGGKLSEGINFQDDLCRAVVMVGLPFPNIFSGELIVKRKHLAAKIMKSGGTEEEASRATKEFMENICMKAVNQSVGRAIRHANDYANIYLLDVRY------NRPNFRK---KLSRWVQDSINSEHTTHQVISSTRKFF 853          

Query:  544 KIYYCSRTHSQLNQVLQEL--------LKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNP--AARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLK------------------QLKSYIRKYLQRFSSKNLLYLRQ--------------LETIFSNL------IEFVSRKIDSYSS----LSCVEFLFKTYLNEMKLDRILNFIDKSKLAY---KLRNSMRNIETGDVVVVRPRQSSALFG--------GNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQN---NTNSLISELKSFFQ 2529
            KI YCSRT S++ + L EL         +  Y +        SR+NLC++  V++ +   +++EKC  +        Q    L +  +     C   ++   IE V   + +     E+L+    +   CP++ +++  +  ++++  Y  +L+P  A R+++++  KD+IVIFDEAHN+ +   +  S+ L    L    +                  +L+    K +Q   S ++L  ++               E I  N+      + F+ R I+   +    L  +    K++L  +K    L FI++  L +   +L   +R +E  +V      +  A F         G  LI E          E+ NA   V N I   +  LDASI +                 K +  +  S+I+  GT+ P   +   L  N +    + +  +      AK+    M +   S  V +   FE RN+ ++++  G + +      P+G+V+FF SY  M+ I+  WQ+ G+L E+ K K + +E   +   E  +A+ T              +  +  + +GA+L +V   K+SEGI+F  +  R V+++GIP+  T S IL+ ++ ++ + Y    +  +  + AM+   Q +GR +R K+D+  ++L D R++           + +  LP W+   +S  +   +T+  IS  K F +
Sbjct:   68 KIIYCSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPEVSKERKGTVVDEKCRRMT-----NGQAKRKLEEDPEANVELCEYHENLYNIE-VEDYLPKGVFSFEKLLKYCEEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVS-KDSIVIFDEAHNIDNVCIESLSLDLTTDALRRATRGANALDERISEVRKVDSQKLQDEYEKLVQGLHSADILTDQEEPFVETPVLPQDLLTEAIPGNIRRAEHFVSFLKRLIEYLKTRMKVLHVISETPKSFLQHLKQ---LTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYEEGFLLIIEPY--------EIENA--AVPNPIMR-FTCLDASIAI-----------------KPVFERFSSVIITSGTISPLDMYPRML--NFKTVLQKSYAMTL-----AKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEFAKITPDGMVVFFPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDA--QETSLALET--------------YRKACSNGRGAILLSVARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENYRIRENDFLSFD-AMRHAAQCLGRVLRGKDDYGVMVLADRRFS-----------RKRSQLPKWIAQGLSDADLNLSTDMAISNTKQFLR 722          

Query:  490 DEEVSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKN--IIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLL---LSHLVTGLKQLKSYIR------KYLQRFSSKNLLYLRQLETIFSNL------IEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDK--SKLAYKLRNSMRNIE--TGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTV-----RNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQ-CRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTA--SAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRI-------MYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFFQ 2529
            D+  SN   N E    I KI Y SRTHSQL+Q +QEL  T Y  +++    GSR+ LCIN+ V +  S +     C                    R   T   C F  Y  +E    N       +DIE LV  G K   CP+Y  ++    A ++ MPY  +L+P +R A  +++  +IV+FDEAHNL     +  S  L    ++  V  +     Y+          +  +  +   L+ L+ +FS L      I+  S    S+      E L    +     DR+L  ++K  + LA  LR     ++  T  + +V  +       GN      Q++ +    + G  + T      +   +++Y+    S  +   + + +    PG  +KD+++Q   S+I+  GT+ P + F+      AE            HVI  K QM V  +        L  ++E R+    +   G+   +     PNG+++FF SY VM+K +E WQ+ G+ + + + K ++ EP+                G    +  M +F A  +  S  GA  FAV   K+SEG++FSD   R V+I G+P+P      ++ KMS++++    + S I        Y   A + VNQA+GR IRH+ DF AI+L D R+     + E         LPSW+K  V I      +  EL  FF+
Sbjct:   99 DDSCSNKGSNFE----IPKIIYASRTHSQLSQAVQELKATVYRPRVS--IIGSREQLCINSDVLKQDSNSAKVHMC--------------------RAKVTARTCHF--YNNLEGNKSNPAFTTEILDIEDLVRLGQKHKVCPYYMARELKTSADIIFMPYNYLLDPKSRKAHNLDISGSIVVFDEAHNLEKVCEETVSFDLTSFDIASCVEDVLLCMEYVANAEDDPDIGEGGTDIDPEDLKVLKALFSKLEEEIDQIQLPSDGSKSFPGDFMFELLGNVGIKPNTKDRVLETLEKINTLLANGLRGKHFALQKFTDALQIVFNKTDKGPKSGNSFKVHVQVEPDSKKKQKGLDIWTSGSKLSKKGTSSLYF---YSFFMRTMIMIHYWCFSPGHAMKDLMSQGVSSVILTSGTLSPLNSFT------AEMQIPFPIRLENPHVIE-KHQMMVAVVTKAPDGATLNSSYEFRSTPGYMTGLGNTIANFARTIPNGLLVFFPSYPVMNKCLEHWQNTGIWARLSQYKPMFAEPR----------------GKGDFVQTMEDFYAKINDPSLNGATFFAVCRGKVSEGLDFSDINGRAVVITGLPFPPMMDAKVKLKMSFLDEMSRKDKSAIKGLTGREWYRQQASRAVNQAVGRVIRHRQDFGAILLCDVRFTYPDALRE---------LPSWVKPQVKIFKEFGHVQRELIQFFR 751          

Query:   49 NFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
            +FP++PY  Q+  M ++   ++ RK  + ESPTGTGK+L +LC++L W
Sbjct:   10 DFPFKPYDCQVAYMEKVIECLQTRKNAVLESPTGTGKTLCLLCATLAW 57          

Query: 1570 LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKD 2469
            L F  +D    +K + ++ +S+++  GT+ P   +   L         R  T +   +  A+  +  M +   S  V +   FE R + A+I+  G++   + +  P+G+V FF+SY  M+ ++  W  +G++S I+K K ++IE   +   E  +A              + N+  + ++ +GA+L +V   K+SEGI+F     R VI+ GIPY  T+S IL+ ++ Y+ +Q+    +  +  + AM+   Q +GRAIR K D+  ++  D+R++ + K       +GK  LP W+++
Sbjct:  409 LHFSCMDASIAVKPVFDRFQSVVITSGTLSPIDMYPKIL-------DFRPVTMATFTMTLARTCLCPMIVSRGSDQVAMTTKFEMREDLAVIRNYGNLLTEMSAVVPDGIVCFFTSYLYMESVVSLWHDQGIISNIQKNKLLFIETTDA--AETSLA--------------LHNYQKACENGRGAILLSVARGKVSEGIDFDHHYGRAVIMFGIPYVYTQSRILKARLEYLREQFNIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGIMVFADKRFSKVDK-------RGK--LPKWIQE 675          

Query:  538 ITKIYYCSRTHSQLNQVLQELLK-TSYADK-------IATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHP--MDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKL 1089
            +TK+ YCSRT  ++ +V++EL K T Y +        I      SR+NLCI+  V   +    ++ KCL +     +         K ++ ++   C+F  YE  + + ++    P   +++ L   G K G CP++  +++   A++++  Y  ML+P  A L SK   K  +V+FDEAHN+ +   D  SV +
Sbjct:   43 LTKLIYCSRTVPEIEKVMEELKKLTEYYESETGEKPNILALALSSRKNLCIHPEVAGEREGKKVDGKCLSMTASFVRL--------KHKEDSSVPVCNF--YEDFDSLGRDEKMPPGSYNLDDLRQFGRKKGWCPYFLARRAIYHANVIVYSYHYMLDPKIADLVSKELDKKAVVVFDEAHNIDNVCIDSMSVTI 227          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQEN---------QMNELIKNKLEIKQIEDDSQNDFDWINAYAQSKK-----SKLNLTD----QNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQ--------ESNEENFVVNYNSDEEVSN---------DIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI----DSYSSLSCVE------FLFKTYLNEMKLDRILNFIDKSKLAYKLR-------NSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDEL-----------GNAMLTVRNFIAAVYYS-LDASILVEKDVGLT-----FLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMK-VMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQY----GSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFF 2526
            F FPY+PY  Q + M  LY  +++ K+GIFESPTGTGKSLS++C +L+WL  ++E          Q  E   +    +     S  + DWI  + Q K      SKL   D    + E+  +      Q+K    +K   +   FK    S +        + +EE+ V  Y SD++  +         + E++  E  +TKIYYCSRTHSQL Q + E+ K+ ++  I+    GSRQNLCIN  V +L SI  IN++C+++QK      Q  E  AK+++    + C F     ++++   ++    DIEQL+  G     CP+Y  + +   A LV++PYQ +L+ A R A+ +++K  +VI DEAHNL DT+S ++S +L  S L     QL  Y  +Y  R  +KNL+Y++Q+      L+  +  K+     S ++ +  E      FLFK  ++ +   ++  + +KS ++ KL         S   + T + +    R++  L    + +K NQ  +     +L            + M+ +  F  A+  S  D  +LV +   L+     FL+++P  +  +++ +CRS+I+ GGTMQP SDF   L  +A    +RI  F+C HVI  +  +  VM  G + +   L FTF++R+   M+  TG I  +I +  P GVV FF SY  + +I+  W++ G L+ +   K ++ EPK+  Q E+V++ F++          ++     +    GA+LF+V+G KMSEGINFSD+L R V++VG+PYP  +SP LQEKMSY++K      G    + +  NL MK VNQ+IGRAIRH+ D+++++L D RY+    +S+         LP+W++   S         + L+ FF
Sbjct:    8 FPFPYQPYDIQEQFMQALYRALDQSKVGIFESPTGTGKSLSLICGALSWLRDHEEKTIQEAAALLQEGEAALSTSAAQSSSTSSSAEPDWITDFVQKKAERDLVSKLKEEDLKRKKREERLEMIRNNAQLKYALKRKSHEDEEAFKLLQLSKEDQAEAPEDQEDEEHIVAEYESDDDSKSRSRLLGRDDEEEDELVEEHVTKIYYCSRTHSQLAQFVHEVQKSPFSKDISLVTLGSRQNLCINEEVRRLGSIQRINDRCMEMQKN-KHEKQRPEDGAKRKRGPAKSVCPFNKASALQQMRDEVLGTVYDIEQLIKVGKDIHSCPYYATRLAIPPAKLVVLPYQMVLHEATRRAAGVQLKGQVVIIDEAHNLSDTLSCIHSSELNGSQLCRAYSQLTQYADRYKSRLKAKNLMYIKQILFAIERLVRVLGGKVGQNPQSQNTQAGTEMHTINNFLFKAEIDNINWFKLQRYFEKSMISRKLSGFVEKYAGSGVTLHTQNTLNKENRRTEGLLNYLKTLKSNQNSASVPQPDLQESAEAEKVLSASPMMQIEGFFMALTNSNTDGRVLVHRQGTLSESSIKFLLLNPAVHFAEVLKECRSVIIAGGTMQPVSDFKEELLLSAGVGQERIVEFACGHVIPPENILPIVMCSGPSGQE--LDFTFQSRDLPCMMDETGRILSNICNVVPGGVVCFFPSYEYLRRIMCHWEASGALTRLSNKKKIFQEPKKPNQVEHVLSEFSR---------CIQRCAQESSGLTGALLFSVVGGKMSEGINFSDDLGRCVVMVGMPYPNIKSPELQEKMSYLDKHLPHSQGKSPGQALVENLCMKAVNQSIGRAIRHRGDYSSVVLCDRRYSRPATLSK---------LPAWIRSRTSTYATFGPAFAALRKFF 887          

Query:  538 ITKIYYCSRTHSQLNQVLQELLK--------TSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPM-----DIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISD---VNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEF-----VSRKIDSYSSLSCV--EFLFKTYLNEMK--------LDRILNFI-DKSKLAYKLRNS----MRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGN-----AMLTVRNFIAAV-YYSLDASILVEK---------DVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVS 2478
            +TK+ YCSRT  ++ +V++EL K        T   +        SR+NLCI+  V+ L+    ++ KC  L     +        A++        C F  YE+ + V + +   P+     +++ L   G + G CP+Y  + S   A++V+  Y  +L+P  A L SK   K ++V+FDEAHN+ +   D   VN  +  L    + ++ L+  I    Q+    +   LR+    +  L+E      V+R+ D Y +   +  E L +     ++        L R L ++  + ++ + ++ S    +++I     +  +P +  A           ++ S   T E+ +     A+  + NF   V  YSL  +I++E          +  L F  +DP   +K +  + +S+++  GT+ P   +   L         R  T +   +  A+  +  + +G  +  V L   FE R + A+I+  G++ L + +  P+G+V FF+SY  M+ I+  W  +G+L  I++ K ++IE + + +                    +  +  + ++ +GA+L +V   K+SEGI+F     R VI+ G+PY  T+S IL+ ++ Y+  Q+    +  +  + AM+   Q +GRAIR K D+  +I  D+RYA   K       +GK  LP W+++ +S
Sbjct:   67 VTKLIYCSRTVPEIEKVVEELRKLMEFYAKETGEVNNFLALALSSRKNLCIHPEVSSLRFGKEVDGKCHSLTASYIR--------AQRHSNPDQPVCRF--YEEFDAVGRQV---PLPAGIYNLDDLKDFGRRKGWCPYYLARYSILHANIVVYSYHYLLDPKIADLVSKELAKKSVVVFDEAHNIDNVCIDSMSVNITRRTLDRCQSNVETLQHTI----QKIKDTDAAKLREE---YRRLVEGLKEANVARETDVYLANPVLPDEILQEAVPGSIRTAEHFLGFLRRFLEYLKSRLRVHHVVQESAPQFLKDIFEKVCIDRKPLRFCA----------ERLQSLLRTLEIADIADFSAVTLISNFATLVSTYSLGFTIIIEPFDDRTPTIANPVLHFSCMDPSIAIKPVFQRFQSVVITSGTLSPLDIYPKIL-------DFRPVTMASFTMTLARTCLCPLIVGRGNDQVALSSKFETREDFAVIRNYGNLLLEMSAIVPDGIVAFFTSYVYMENIVASWYEQGILENIQRNKLIFIETQDAAETSMA----------------LEKYQEACENGRGAILLSVARGKVSEGIDFVHHFGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGLMIFADKRYARADK-------RGK--LPRWIQEHIS 702          

Query:  538 ITKIYYCSRTHSQLNQVLQELLK--------TSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPM-----DIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPA-ARLASKIEVKDNIVIFDEAHNLPDTISD---VNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEF-----VSRKIDSYSSLSCV--EFLFKTYLNEMK--------LDRILNFI-DKSKLAYKLRNS----MRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGN-----AMLTVRNFIAAV-YYSLDASILVEK---------DVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVS 2478
            +TK+ YCSRT  ++ +V++EL K        T   +        SR+NLCI+  V+ L+    ++ KC  L          +   A++        C F  YE+ + V + +   P+     +++ L   G + G CP+Y  + S   A++V+  Y  +L+P  A L SK   K ++V+FDEAHN+ +   D   VN  +  L    + ++ L+  I    Q+    +   LR+    +  L+E      V+R+ D Y +   +  E L +     ++        L R L ++  + ++ + ++ S    +++I     +  +P +  A           ++ S   T E+ +     A+  + NF   V  YSL  +I++E          +  L F  +DP   +K +  + +S+++  GT+ P   +   L         R  T +   +  A+  +  + +G  +  V L   FE R + A+I+  G++ L + +  P+G+V FF+SY  M+ I+  W  +G+L  I++ K ++IE + + +                    +  +  + ++ +GA+L +V   K+SEGI+F     R VI+ G+PY  T+S IL+ ++ Y+  Q+    +  +  + AM+   Q +GRAIR K D+  +I  D+RYA   K       +GK  LP W+++ +S
Sbjct:   67 VTKLIYCSRTVPEIEKVVEELRKLMEFYAKETGEVNNFLALALSSRKNLCIHPEVSSLRFGKEVDGKCHSLTA--------SYIRAQRHSNPDQPVCRF--YEEFDAVGRQV---PLPAGIYNLDDLKDFGRRKGWCPYYLARYSILHANIVVYSYHYLLDPKIADLVSKELAKKSVVVFDEAHNIDNVCIDSMSVNITRRTLDRCQSNVETLQHTI----QKIKDTDAAKLREE---YRRLVEGLKEANVARETDVYLANPVLPDEILQEAVPGSIRTAEHFLGFLRRFLEYLKSRLRVHHVVQESAPQFLKDIFEKVCIDRKPLRFCA----------ERLQSLLRTLEIADIADFSAVTLISNFATLVSTYSLGFTIIIEPFDDRTPTIANPVLHFSCMDPSIAIKPVFQRFQSVVITSGTLSPLDIYPKIL-------DFRPVTMASFTMTLARTCLCPLIVGRGNDQVALSSKFETREDFAVIRNYGNLLLEMSAIVPDGIVAFFTSYVYMENIVASWYEQGILENIQRNKLIFIETQDAAETSMA----------------LEKYQEACENGRGAILLSVARGKVSEGIDFVHHFGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGLMIFADKRYARADK-------RGK--LPRWIQEHIS 702          

Query: 1570 LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCE----HVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVE---KQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSF 2523
            L+F  ++P     D+    RS+++  GT+ P   FS+ L             FS +    HVIN K Q+ V T+G   +   L  TF++    A     GD+ L I      GV+ F  SY ++DK+ + W + G+  ++++ K+V  EP+   + +               L    +         GA+L AV   K+SEG++F+D+ AR V+ +GIP+P  +   ++ KM Y +   K  G       Y   A + +NQA+GR IRHKND+ A+IL+D+RY        N   K   GL  W++  V      ++ +  LK+F
Sbjct:  609 LSFWCLNPAVAFSDLSGSVRSIVLTSGTLSPMGSFSSELGVK----------FSIQLEANHVIN-KSQVWVGTVGAGPQGKKLCATFQHTETYAFQDEVGDLLLHICKVIAKGVLCFLPSYKLLDKLRDRWSNTGLWEKLEQQKTVITEPRGGAKGD-----------FDELLQTYYDAIKCCDERDGALLIAVCRGKVSEGLDFTDDNARAVVTIGIPFPNIKDLQVELKMKYNDQHCKSRGLLPGHRWYEIQAYRALNQALGRCIRHKNDWGALILVDDRYG-------NNPNKYITGLSKWVRQLVQHHYTFSNAMQSLKAF 904          

Query:  520 QENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDL-QKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNL 1173
            ++++  I KI++ +RTH Q+ Q+  EL +T Y+  +      SR + C+N  V  +   N  NE+C DL +   GK+ +    + K R            +  ++ V  + +    D+E LV    +   C +Y  ++    A ++  PY  +L+P  R + +I++   I++ DEAHN+ D   +  S  L  S L T  ++L S ++  ++R   + L
Sbjct:  253 KDDKKRIPKIFFGTRTHKQITQIAHELKRTVYSS-VHMTILSSRDHTCVNPEV--VPHFNR-NERCKDLLEAKNGKSCRFYHGVQKMR-----------DHHTLQRV--HGLHEAWDVEDLVTVAKRLRSCSYYAARELMQGASIIFCPYNYLLDPMIRESMEIDLAGQILVLDEAHNIEDCARESTSFTLDESSLKTCREELDSMVKNNIRRSQHEPL 454          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
             +FP + YP Q+ +M+ +   +   +  + ESPTG+GKSL++LCS+L W
Sbjct:   15 IHFPCKAYPSQLSMMNSIVRGLNYGQHCLLESPTGSGKSLALLCSTLAW 63          

Query: 1570 LTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCE----HVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAK---SNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVE---KQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSF 2523
            L+F  ++P     D+    RS+++  GT+ P   FS+ L             FS +    HVIN K Q+ V T+G   +   L  TF++    A     GD+ L I      GV+ F  SY ++DK+ + W + G+  ++++ K+V  EP+   + +     F +         +++ +  + K      GA+L AV   K+SEG++F+D+ AR V+ +GIP+P  +   ++ KM Y +   K  G       Y   A + +NQA+GR IRHKND+ A+IL+D+RY        N   K   GL  W++  V      ++ +  LK+F
Sbjct:  609 LSFWCLNPAVAFSDLSGSVRSIVLTSGTLSPMGSFSSELGVK----------FSIQLEANHVIN-KSQVWVGTVGAGPQGKKLCATFQHTETYAFQDEVGDLLLHICKVIAKGVLCFLPSYKLLDKLRDRWSNTGLWEKLEQQKTVITEPRGGAKGD-----FDE---------LLQTYYDAIKCCDERDGALLIAVCRGKVSEGLDFTDDNARAVVTIGIPFPNIKDLQVELKMKYNDQHCKSRGLLPGHRWYEIQAYRALNQALGRCIRHKNDWGALILVDDRYG-------NNPNKYITGLSKWVRQLVQHHYTFSNAMQSLKAF 904          

Query:  520 QENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDL-QKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNL 1173
            ++++  I KI++ +RTH Q+ Q+  EL +T Y+  +      SR + C+N  V  +   N  NE+C DL +   GK+ +    + K R            +  ++ V  + +    D+E LV    +   C +Y  ++    A ++  PY  +L+P  R + +I++   I++ DEAHN+ D   +  S  L  S L T  ++L S ++  ++R   + L
Sbjct:  253 KDDKKRIPKIFFGTRTHKQITQIAHELKRTVYSS-VHMTILSSRDHTCVNPEV--VPHFNR-NERCKDLLEAKNGKSCRFYHGVQKMR-----------DHHTLQRV--HGLHEAWDVEDLVTVAKRLRSCSYYAARELMQGASIIFCPYNYLLDPMIRESMEIDLAGQILVLDEAHNIEDCARESTSFTLDESSLKTCREELDSMVKNNIRRSQHEPL 454          

Query:   46 FNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNW 192
             +FP + YP Q+ +M+ +   +   +  + ESPTG+GKSL++LCS+L W
Sbjct:   15 IHFPCKAYPSQLSMMNSIVRGLNYGQHCLLESPTGSGKSLALLCSTLAW 63          

Query:   25 MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFF 2526
            MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWI+AYAQSKKSKLNLTDQNEDLEKKKIILDQIKLIKLKKESINNTTFKDCNYS+QESNEENFVVNYNSDEEVSNDIENQE EGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGL QLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPS+RIHTFSCEHVINAKQQMKVMTLGV+SKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIE KQSLQNEN                IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFF
Sbjct:    1 MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWISAYAQSKKSKLNLTDQNEDLEKKKIILDQIKLIKLKKESINNTTFKDCNYSHQESNEENFVVNYNSDEEVSNDIENQETEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLNQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSNRIHTFSCEHVINAKQQMKVMTLGVDSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEQKQSLQNEN----------------IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFF 818          

Query:   79 MKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFF 2526
            MKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWI+AYAQSKKSKLNLTDQNEDLEKKKIILDQIKLIKLKKESINNTTFKDCNYS+QESNEENFVVNYNSDEEVSNDIENQE EGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGL QLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPS+RIHTFSCEHVINAKQQMKVMTLGV+SKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIE KQSLQNEN                IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFF
Sbjct:    1 MKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWISAYAQSKKSKLNLTDQNEDLEKKKIILDQIKLIKLKKESINNTTFKDCNYSHQESNEENFVVNYNSDEEVSNDIENQETEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLNQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSNRIHTFSCEHVINAKQQMKVMTLGVDSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEQKQSLQNEN----------------IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSYVEKQYGSESSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDERYADITKISENELRKGKLGLPSWLKDSVSIQNNTNSLISELKSFF 800          

Query:   25 MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWINAYAQSKKSKLNLTDQNEXXXXXXXXXXXXXXXXXXXXSINNTTFKDCNYSNQESNEENFVVNYNSDEEVSNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFF 1911
            MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWI+AYAQSKKSKLNLTDQNEDLEKKKIILDQIKLIKLKKESINNTTFKDCNYS+QESNEENFVVNYNSDEEVSNDIENQE EGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGL QLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPS+RIHTFSCEHVINAKQQMKVMTLGV+SKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCP    I +
Sbjct:    1 MSNQFYAFNFPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWLLVNQENQMNELIKNKLEIKQIEDDSQNDFDWISAYAQSKKSKLNLTDQNEDLEKKKIILDQIKLIKLKKESINNTTFKDCNYSHQESNEENFVVNYNSDEEVSNDIENQETEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHPMDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPDTISDVNSVKLLLSHLVTGLNQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKIDSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMRNIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATDELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSNRIHTFSCEHVINAKQQMKVMTLGVDSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPKHFYIIW 629          

Query:  502 SNDIENQENEGSITKIYYCSRTHSQLNQVLQELLKTSYADKIATCCFGSRQNLCINATVNQLKSINLINEKCLDLQKPIGKTDQITETLAKKRKVTTGACCSFKSYEKIEEVSKNIIRHP---MDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPD----------TISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---------DSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMR-NIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATD--------------ELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSY---VEKQYGSE--SSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDER 2394
            S + E +EN   + KI++ +RTH Q+ QV++EL K++Y++   +   G R   C+N  V   K I+   + C DL K +G                    C +K   +          HP    DIE + +   K   CP++  K     A +V  PY  +LNP  R +  + +++NI+I DEAHN+ D          ++ D++ +K+LL H+          ++K  +     +LL +  LE +   +IE +S K+          ++   S V+ L    L+   L+ I NF  ++ LA KLRN +R N E  D     P     L     ++ +  MDS+K                 E  N  +    +I+      D   ++  +  L    ++PG   K I +  RS+I+  GT+ P   F   L     C    I  F   HV+  ++   + ++G       ++  F   +  +     G + L      PNG++IF SS+ +++  ++ W + G+++EI+K KS++IEP+Q+ +    I  + K                      GA+L AV   K SEG++F+DE ARLVI VGIPYP    P +  KM+Y    +K +  +  S    Y+  A + +NQA+GR IRH+ D+ A+I++D R
Sbjct:   71 SRNDECKENAKQV-KIFFGTRTHKQIGQVIRELKKSAYSNTRMSILSG-RNLSCLNQEVLMSKEID---QNCKDLCKKMG--------------------CIYKIDNQ---------PHPETTWDIESISMKLKKVKICPYFQFKSWMKSADIVFCPYNYILNPFIRKSMGVNLENNIIILDEAHNIEDICREGASMSISLKDIDYLKMLLPHI----------LKKSGKEDCQHDLLTM--LEKM-HEVIELLSSKLFYKDEDVLKKTWDLESFVQLLKNCQLD---LENIKNF--ENHLA-KLRNEIRVNEEITDSTSEIPSSFMQLIDSFIMLVKLMMDSDKTKQNDFSIVITEGEKYAEPINEKVASGEWISCKKRKAD---VLNNNFVLNIWCMNPGIVFKQISDISRSIILTSGTLSPVVSFEKEL----NCKFSAI--FQAGHVVQPEKTF-LASIGNGPSGNAMKAVFSTTSKLSFQDELGQMLLKCSEVVPNGILIFLSSFALIELFMQRWTNTGLINEIRKHKSIFIEPRQTSEMNECIDAYFKH------------------VKDGALLLAVFRGKASEGVDFADEAARLVITVGIPYPSIADPKVVLKMNYNTNKKKHFDDQLLSGNEWYNIQAFRALNQALGRCIRHREDWGAMIMIDSR 662          

Query:   52 FPYEPYPQQMKLMSELYATIEKRKIGIFESPTGTGKSLSVLCSSLNWL 195
            FP EPYPQQ+ +M  +  +I K +  + E PTG+GK++++LCS+L WL
Sbjct:   13 FPIEPYPQQLYMMRRIINSINKSENCLMELPTGSGKTIALLCSTLGWL 60          

Query:  856 HP---MDIEQLVVAGLKSGGCPFYGIKKSFNKAHLVLMPYQNMLNPAARLASKIEVKDNIVIFDEAHNLPD----------TISDVNSVKLLLSHLVTGLKQLKSYIRKYLQRFSSKNLLYLRQLETIFSNLIEFVSRKI---------DSYSSLSCVEFLFKTYLNEMKLDRILNFIDKSKLAYKLRNSMR-NIETGDVVVVRPRQSSALFGGNQLIKENQMDSEKATD--------------ELGNAMLTVRNFIAAVYYSLDASILVEKDVGLTFLVVDPGKYLKDIVNQCRSMIVIGGTMQPFSDFSNRLFKNAECPSDRIHTFSCEHVINAKQQMKVMTLGVNSKNVPLRFTFENRNNEAMIKATGDIFLSIFSFCPNGVVIFFSSYNVMDKIIEEWQSKGVLSEIKKLKSVYIEPKQSLQNENVIAIFTKQ*GLIRRL*IMRNFTASAKSNKGAVLFAVIGAKMSEGINFSDELARLVIIVGIPYPQTRSPILQEKMSY---VEKQYGSE--SSRIMYHNLAMKPVNQAIGRAIRHKNDFAAIILLDER 2394
            HP    DIE + +   K   CP++  K     A +V  PY  +LNP  R +  + +++NI+I DEAHN+ D          ++ D++ +K+LL H+          ++K  +     +LL +  LE +   +IE +S K+          ++   S V+ L    L+   L+ I NF  ++ LA KLRN +R N E  D     P     L     ++ +  MDS+K                 E  N  +    +I+      D   ++  +  L    ++PG   K I +  RS+I+  GT+ P   F   L     C    I  F   HV+  ++   + ++G       ++  F   +  +     G + L      PNG++IF SS+ +++  ++ W + G+++EI+K KS++IEP+Q+ +    I  + K                      GA+L AV   K SEG++F+DE ARLVI VGIPYP    P +  KM+Y    +K +  +  S    Y+  A + +NQA+GR IRH+ D+ A+I++D R
Sbjct:   12 HPETTWDIESISMKLKKVKICPYFQFKSWMKSADIVFCPYNYILNPFIRKSMGVNLENNIIILDEAHNIEDICREGASMSISLKDIDYLKMLLPHI----------LKKSGKEDCQHDLLTM--LEKM-HEVIELLSSKLFYKDEDVLKKTWDLESFVQLLKNCQLD---LENIKNF--ENHLA-KLRNEIRVNEEITDSTSEIPSSFMQLIDSFIMLVKLMMDSDKTKQNDFSIVITEGEKYAEPINEKVASGEWISCKKRKAD---VLNNNFVLNIWCMNPGIVFKQISDISRSIILTSGTLSPVVSFEKEL----NCKFSAI--FQAGHVVQPEKTF-LASIGNGPSGNAMKAVFSTTSKLSFQDELGQMLLKCSEVVPNGILIFLSSFALIELFMQRWTNTGLINEIRKHKSIFIEPRQTSEMNECIDAYFKH------------------VKDGALLLAVFRGKASEGVDFADEAARLVITVGIPYPSIADPKVVLKMNYNTNKKKHFDDQLLSGNEWYNIQAFRALNQALGRCIRHREDWGAMIMIDSR 519