BMP

Overview
NameBMP (ABV04322.1)
Smed IDSMED30014877
Length (bp)1471
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of BMP (SMED30014877) t-SNE clustered cells

Violin plots show distribution of expression levels for BMP (SMED30014877) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of BMP (SMED30014877) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for BMP (SMED30014877) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30014877

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 15

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
dorsal region of the whole animalSMED30014877h1SMcG0003348 ABV04322.1smed_ncbi_20240424PMID:23318641
Chen et al., 2013
whole organism asexual adult colorimetric in situ hybridization evidence
eyeSMED30014877h1SMcG0003348 EF633689.1smed_ncbi_20240424PMID:22451003
González-Sastre et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30014877h1SMcG0003348 dd_Smed_v4_17402_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30014877h1SMcG0003348 dd_Smed_v6_17402_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
dorsal midlineSMED30014877h1SMcG0003348 ABV04322.1smed_ncbi_20240424PMID:17942485
Reddien et al., 2007
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal midlineSMED30014877h1SMcG0003348 EF633689.1smed_ncbi_20240424PMID:21295481
Molina et al., 2011
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal midlineSMED30014877h1SMcG0003348 ABV04322.1smed_ncbi_20240424PMID:21295483
Gaviño et al., 2011
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal region of the whole animalSMED30014877h1SMcG0003348 ABV04322.1smed_ncbi_20240424PMID:21295483
Gaviño et al., 2011
whole organism asexual adult colorimetric in situ hybridization evidence
Category 2 cellSMED30014877h1SMcG0003348 dd_Smed_v4_17402_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
dorsal midlineSMED30014877h1SMcG0003348 Smed-BMPsmed_ncbi_20240424PMID:17905225
Molina et al., 2007
whole organism asexual adult colorimetric in situ hybridization evidence
esophagusSMED30014877h1SMcG0003348 Smed-BMPsmed_ncbi_20240424PMID:17905225
Molina et al., 2007
whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30014877h1SMcG0003348 Smed-BMPsmed_ncbi_20240424PMID:17905225
Molina et al., 2007
whole organism asexual adult colorimetric in situ hybridization evidence
dorsal midlineSMED30014877h1SMcG0003348 EF633689smed_ncbi_20240424PMID:17905225
Molina et al., 2007
whole organism asexual adult colorimetric in situ hybridization evidence
esophagusSMED30014877h1SMcG0003348 EF633689smed_ncbi_20240424PMID:17905225
Molina et al., 2007
whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30014877h1SMcG0003348 EF633689smed_ncbi_20240424PMID:17905225
Molina et al., 2007
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of BMP vs. Ensembl Human
Match: BMP7 (bone morphogenetic protein 7 [Source:HGNC Symbol;Acc:HGNC:1074])

HSP 1 Score: 126.331 bits (316), Expect = 4.071e-31
Identity = 54/136 (39.71%), Postives = 88/136 (64.71%), Query Frame = 3
Query:  891 NQEESTIPKD-ENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            +Q  S  PK+ E +R+  V  + + D  Q+    C+++ L V+F+++GW  WIIAP+ Y AYYC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  300 SQNRSKTPKNQEALRMANVAENSSSDQRQA----CKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH 431          
BLAST of BMP vs. Ensembl Human
Match: BMP7 (bone morphogenetic protein 7 [Source:HGNC Symbol;Acc:HGNC:1074])

HSP 1 Score: 122.094 bits (305), Expect = 4.501e-30
Identity = 45/102 (44.12%), Postives = 72/102 (70.59%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            C+++ L V+F+++GW  WIIAP+ Y AYYC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  264 CKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH 365          
BLAST of BMP vs. Ensembl Human
Match: BMP4 (bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071])

HSP 1 Score: 122.865 bits (307), Expect = 5.136e-30
Identity = 53/123 (43.09%), Postives = 79/123 (64.23%), Query Frame = 3
Query:  930 RLKRVKRDKTDYIQSLED---DCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            R +R KR    + Q       +C+R+SL V F +VGW+ WI+AP  Y A+YC G+CP+PL+D+ N+TNHAI+Q L++ +   SIPK CCVP  L   ++LYL+     +L+ +++M V  C C
Sbjct:  286 RRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNS-SIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407          
BLAST of BMP vs. Ensembl Human
Match: BMP4 (bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071])

HSP 1 Score: 122.865 bits (307), Expect = 5.136e-30
Identity = 53/123 (43.09%), Postives = 79/123 (64.23%), Query Frame = 3
Query:  930 RLKRVKRDKTDYIQSLED---DCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            R +R KR    + Q       +C+R+SL V F +VGW+ WI+AP  Y A+YC G+CP+PL+D+ N+TNHAI+Q L++ +   SIPK CCVP  L   ++LYL+     +L+ +++M V  C C
Sbjct:  286 RRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNS-SIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407          
BLAST of BMP vs. Ensembl Human
Match: BMP4 (bone morphogenetic protein 4 [Source:HGNC Symbol;Acc:HGNC:1071])

HSP 1 Score: 122.865 bits (307), Expect = 5.136e-30
Identity = 53/123 (43.09%), Postives = 79/123 (64.23%), Query Frame = 3
Query:  930 RLKRVKRDKTDYIQSLED---DCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            R +R KR    + Q       +C+R+SL V F +VGW+ WI+AP  Y A+YC G+CP+PL+D+ N+TNHAI+Q L++ +   SIPK CCVP  L   ++LYL+     +L+ +++M V  C C
Sbjct:  286 RRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNS-SIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407          
BLAST of BMP vs. Ensembl Celegans
Match: dbl-1 (DPP/BMP-Like; Decapentaplegic protein homolog [Source:UniProtKB/TrEMBL;Acc:G5EEL5])

HSP 1 Score: 117.472 bits (293), Expect = 7.528e-29
Identity = 50/120 (41.67%), Postives = 73/120 (60.83%), Query Frame = 3
Query:  930 RLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            R  R K  K    ++  + C+R    V F ++ W  WI+AP+ Y+AY C+G+CP P+    NATNHAIIQ L+H L+   +P PCCVP    P ++LY++ +   ++RE+ DM V SC C
Sbjct:  245 RKNRKKGRKHHNTEAESNLCRRTDFYVDFDDLNWQDWIMAPKGYDAYQCQGSCPNPMPAQLNATNHAIIQSLLHSLRPDEVPPPCCVPTETSPLSILYMDVDKVIVIREYADMRVESCGC 364          
BLAST of BMP vs. Ensembl Celegans
Match: dbl-1 (DPP/BMP-Like; Decapentaplegic protein homolog [Source:UniProtKB/TrEMBL;Acc:G5EEL5])

HSP 1 Score: 117.472 bits (293), Expect = 7.528e-29
Identity = 50/120 (41.67%), Postives = 73/120 (60.83%), Query Frame = 3
Query:  930 RLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            R  R K  K    ++  + C+R    V F ++ W  WI+AP+ Y+AY C+G+CP P+    NATNHAIIQ L+H L+   +P PCCVP    P ++LY++ +   ++RE+ DM V SC C
Sbjct:  245 RKNRKKGRKHHNTEAESNLCRRTDFYVDFDDLNWQDWIMAPKGYDAYQCQGSCPNPMPAQLNATNHAIIQSLLHSLRPDEVPPPCCVPTETSPLSILYMDVDKVIVIREYADMRVESCGC 364          
BLAST of BMP vs. Ensembl Celegans
Match: tig-2 (TransformIng Growth factor beta family [Source:UniProtKB/TrEMBL;Acc:O16273])

HSP 1 Score: 102.834 bits (255), Expect = 7.807e-24
Identity = 45/132 (34.09%), Postives = 75/132 (56.82%), Query Frame = 3
Query:  903 STIPKDENIRLKRVKRDKTDYIQSLEDD--CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            ST P       ++VKR ++ Y +   ++  CQR  L V F  +GW +W+IAP+ ++A+YC G+C  P S   NAT+HAI+Q  +H ++  S     C P +L    +L++++     ++ ++DM V  C CH
Sbjct:  235 STTPISAPPMRQKVKRSESAYFEKPNENERCQRKGLYVDFDILGWKQWVIAPEGFSAFYCSGDCSAPFSKEMNATSHAIVQSTLHRVRPNSTTPAKCAPSSLGSYKILFVDQNKQVQIKRYRDMVVDECGCH 366          
BLAST of BMP vs. Ensembl Celegans
Match: unc-129 (UNC-129 [Source:UniProtKB/TrEMBL;Acc:G5EBY8])

HSP 1 Score: 77.0258 bits (188), Expect = 5.592e-15
Identity = 31/101 (30.69%), Postives = 53/101 (52.48%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            C +  ++V+ K  GW +++I P+     +CKG C  P+  +  A+NHA++Q L       +    CC P NL+     Y + +G  ++R +  M + SCSC
Sbjct:  312 CHKEGVLVSLKHFGWDRYVIEPKTIETSFCKGKCAKPMLTSGKASNHAMLQSL------FAAEPVCCAPTNLKSLNFWYRDEKGRTVIRNYSKMLIGSCSC 406          
BLAST of BMP vs. Ensembl Celegans
Match: unc-129 (UNC-129 [Source:UniProtKB/TrEMBL;Acc:G5EBY8])

HSP 1 Score: 77.0258 bits (188), Expect = 5.592e-15
Identity = 31/101 (30.69%), Postives = 53/101 (52.48%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            C +  ++V+ K  GW +++I P+     +CKG C  P+  +  A+NHA++Q L       +    CC P NL+     Y + +G  ++R +  M + SCSC
Sbjct:  312 CHKEGVLVSLKHFGWDRYVIEPKTIETSFCKGKCAKPMLTSGKASNHAMLQSL------FAAEPVCCAPTNLKSLNFWYRDEKGRTVIRNYSKMLIGSCSC 406          
BLAST of BMP vs. Ensembl Fly
Match: dpp (gene:FBgn0000490 transcript:FBtr0077771)

HSP 1 Score: 130.568 bits (327), Expect = 3.396e-32
Identity = 49/104 (47.12%), Postives = 73/104 (70.19%), Query Frame = 3
Query:  978 EDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +D C+R+SL V F +VGW  WI+AP  Y+AYYC G CP+PL+D+FN+TNHA++Q L++ +    +PK CCVP  L    +LYLN +   +L+ +++M+V  C C
Sbjct:  484 DDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587          
BLAST of BMP vs. Ensembl Fly
Match: dpp (gene:FBgn0000490 transcript:FBtr0077773)

HSP 1 Score: 130.568 bits (327), Expect = 3.396e-32
Identity = 49/104 (47.12%), Postives = 73/104 (70.19%), Query Frame = 3
Query:  978 EDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +D C+R+SL V F +VGW  WI+AP  Y+AYYC G CP+PL+D+FN+TNHA++Q L++ +    +PK CCVP  L    +LYLN +   +L+ +++M+V  C C
Sbjct:  484 DDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587          
BLAST of BMP vs. Ensembl Fly
Match: dpp (gene:FBgn0000490 transcript:FBtr0077775)

HSP 1 Score: 130.568 bits (327), Expect = 3.396e-32
Identity = 49/104 (47.12%), Postives = 73/104 (70.19%), Query Frame = 3
Query:  978 EDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +D C+R+SL V F +VGW  WI+AP  Y+AYYC G CP+PL+D+FN+TNHA++Q L++ +    +PK CCVP  L    +LYLN +   +L+ +++M+V  C C
Sbjct:  484 DDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587          
BLAST of BMP vs. Ensembl Fly
Match: dpp (gene:FBgn0000490 transcript:FBtr0077772)

HSP 1 Score: 130.568 bits (327), Expect = 3.396e-32
Identity = 49/104 (47.12%), Postives = 73/104 (70.19%), Query Frame = 3
Query:  978 EDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +D C+R+SL V F +VGW  WI+AP  Y+AYYC G CP+PL+D+FN+TNHA++Q L++ +    +PK CCVP  L    +LYLN +   +L+ +++M+V  C C
Sbjct:  484 DDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587          
BLAST of BMP vs. Ensembl Fly
Match: gbb (gene:FBgn0024234 transcript:FBtr0072127)

HSP 1 Score: 115.546 bits (288), Expect = 1.223e-27
Identity = 47/102 (46.08%), Postives = 68/102 (66.67%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            CQ  +L + FK++GW  WIIAP+ Y A+YC G C +PL+ + NATNHAI+Q L+H L+   +PKPCC P  L    +LY   + +  L+++++M V SC CH
Sbjct:  354 CQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH 455          
BLAST of BMP vs. Ensembl Zebrafish
Match: bmp2a (bone morphogenetic protein 2a [Source:ZFIN;Acc:ZDB-GENE-980526-388])

HSP 1 Score: 124.79 bits (312), Expect = 3.672e-31
Identity = 49/102 (48.04%), Postives = 75/102 (73.53%), Query Frame = 3
Query:  984 DCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +C+R+SL V F +VGW+ WI+AP  Y+A+YC+G CP+PL+D+ N+TNHAI+Q L++ +   +IP+ CCVP +L P +LLYL+     +L+ ++DM V  C C
Sbjct:  285 NCRRHSLYVDFSDVGWNDWIVAPPGYHAFYCQGECPFPLADHLNSTNHAIVQTLVNSVNS-NIPRACCVPTDLSPVSLLYLDEYERVILKNYQDMVVEGCGC 385          
BLAST of BMP vs. Ensembl Zebrafish
Match: gdf3 (growth differentiation factor 3 [Source:NCBI gene;Acc:30125])

HSP 1 Score: 121.324 bits (303), Expect = 4.351e-30
Identity = 53/118 (44.92%), Postives = 72/118 (61.02%), Query Frame = 3
Query:  939 RVKRDKTDYIQSLEDD-CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            R KR  + Y+     + C+   L + FK+VGW  WIIAPQ Y A YC G CP+PLS++ N TNHAI+Q L+H       P+PCCVP  L P ++LY +   + +LR ++DM V  C C
Sbjct:  237 RRKRSASYYLPVTPSNVCKPRRLYIDFKDVGWQDWIIAPQGYLANYCHGECPFPLSESLNGTNHAILQTLVHSFDPKGTPQPCCVPIKLSPISMLYYDNNDNVVLRHYEDMVVDECGC 354          
BLAST of BMP vs. Ensembl Zebrafish
Match: bmp4 (bone morphogenetic protein 4 [Source:ZFIN;Acc:ZDB-GENE-980528-2059])

HSP 1 Score: 122.094 bits (305), Expect = 4.419e-30
Identity = 50/118 (42.37%), Postives = 77/118 (65.25%), Query Frame = 3
Query:  936 KRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +R KR      +    +C+R++L V F +VGW+ WI+AP  Y AYYC G CP+PL+D+ N+TNHAI+Q L++ + + +IPK CCVP  L   ++LYL+     +L+ +++M V  C C
Sbjct:  283 RRAKRSPKQRGRKRNRNCRRHALYVDFSDVGWNDWIVAPPGYQAYYCHGECPFPLADHLNSTNHAIVQTLVNSV-NTNIPKACCVPTELSAISMLYLDETDRVVLKNYQEMVVEGCGC 399          
BLAST of BMP vs. Ensembl Zebrafish
Match: bmp7b (bone morphogenetic protein 7b [Source:ZFIN;Acc:ZDB-GENE-060929-328])

HSP 1 Score: 122.479 bits (306), Expect = 4.567e-30
Identity = 54/144 (37.50%), Postives = 88/144 (61.11%), Query Frame = 3
Query:  864 GNKAPLPTYNQEESTIPKDENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            GNK   P  ++   T    E +R+  +  + + D  Q+    C+++ L V+F+++GW  WIIAP+ Y AYYC G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  291 GNKQRNPNRSK---TAKGQEALRVANIAENSSADQKQA----CKKHELYVSFRDLGWQDWIIAPEGYAAYYCMGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLHAISVLYFDDSSNVILKKYRNMVVRACGCH 427          
BLAST of BMP vs. Ensembl Zebrafish
Match: bmp7b (bone morphogenetic protein 7b [Source:ZFIN;Acc:ZDB-GENE-060929-328])

HSP 1 Score: 122.479 bits (306), Expect = 4.567e-30
Identity = 54/144 (37.50%), Postives = 88/144 (61.11%), Query Frame = 3
Query:  864 GNKAPLPTYNQEESTIPKDENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            GNK   P  ++   T    E +R+  +  + + D  Q+    C+++ L V+F+++GW  WIIAP+ Y AYYC G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  291 GNKQRNPNRSK---TAKGQEALRVANIAENSSADQKQA----CKKHELYVSFRDLGWQDWIIAPEGYAAYYCMGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLHAISVLYFDDSSNVILKKYRNMVVRACGCH 427          
BLAST of BMP vs. Ensembl Xenopus
Match: bmp7.1 (bone morphogenetic protein 7, gene 1 [Source:NCBI gene;Acc:394805])

HSP 1 Score: 130.183 bits (326), Expect = 1.524e-32
Identity = 56/136 (41.18%), Postives = 88/136 (64.71%), Query Frame = 3
Query:  891 NQEESTIPK-DENIRLKRVKRDK-TDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            NQ  S  PK  E +R+  +  +  TD  Q+    C+++ L V+FK++GW  WIIAP+ Y A+YC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L P ++LY +   + +L+++++M V +C CH
Sbjct:  294 NQNRSKAPKSQEALRVSNIAENSSTDQKQA----CKKHELYVSFKDLGWQDWIIAPEGYAAFYCEGECAFPLNSYMNATNHAIVQTLVHFINPDTVPKPCCAPTQLNPISVLYFDDSSNVILKKYRNMVVRACGCH 425          
BLAST of BMP vs. Ensembl Xenopus
Match: admp (anti-dorsalizing morphogenic protein [Source:NCBI gene;Acc:733983])

HSP 1 Score: 123.635 bits (309), Expect = 1.600e-30
Identity = 55/119 (46.22%), Postives = 78/119 (65.55%), Query Frame = 3
Query:  951 DKTDYIQSLEDD----CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLK-DISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            ++T   +S+EDD    CQR+ L V F+E+GWS WII+P+ YNAY+CKG+CP+PL  N   TNHA +Q +I+ LK    +  PCCVP  L    LLY + + + +L+++ DM   SC CH
Sbjct:  272 NRTRISRSVEDDGQLPCQRHPLYVDFEEIGWSGWIISPRGYNAYHCKGSCPFPLGQNMRPTNHATVQSIINALKLTKGVSSPCCVPDKLFSINLLYFDDDENVVLKQYDDMVAGSCGCH 390          
BLAST of BMP vs. Ensembl Xenopus
Match: nr5a1 (nuclear receptor subfamily 5 group A member 1 [Source:Xenbase;Acc:XB-GENE-485361])

HSP 1 Score: 123.25 bits (308), Expect = 3.824e-30
Identity = 46/102 (45.10%), Postives = 71/102 (69.61%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            C+++ L V+F+++GW  WIIAP+ Y AYYC G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++K+M V +C CH
Sbjct:  335 CKKHELFVSFRDLGWQDWIIAPEGYAAYYCDGECAFPLNSFMNATNHAIVQTLVHFVNPETVPKPCCAPTQLNGISVLYFDDSSNVILKKYKNMVVQACGCH 436          
BLAST of BMP vs. Ensembl Xenopus
Match: nr5a1 (nuclear receptor subfamily 5 group A member 1 [Source:Xenbase;Acc:XB-GENE-485361])

HSP 1 Score: 123.25 bits (308), Expect = 4.317e-30
Identity = 46/102 (45.10%), Postives = 71/102 (69.61%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            C+++ L V+F+++GW  WIIAP+ Y AYYC G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++K+M V +C CH
Sbjct:  323 CKKHELFVSFRDLGWQDWIIAPEGYAAYYCDGECAFPLNSFMNATNHAIVQTLVHFVNPETVPKPCCAPTQLNGISVLYFDDSSNVILKKYKNMVVQACGCH 424          
BLAST of BMP vs. Ensembl Xenopus
Match: nr5a1 (nuclear receptor subfamily 5 group A member 1 [Source:Xenbase;Acc:XB-GENE-485361])

HSP 1 Score: 123.25 bits (308), Expect = 4.317e-30
Identity = 46/102 (45.10%), Postives = 71/102 (69.61%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            C+++ L V+F+++GW  WIIAP+ Y AYYC G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++K+M V +C CH
Sbjct:  323 CKKHELFVSFRDLGWQDWIIAPEGYAAYYCDGECAFPLNSFMNATNHAIVQTLVHFVNPETVPKPCCAPTQLNGISVLYFDDSSNVILKKYKNMVVQACGCH 424          
BLAST of BMP vs. Ensembl Mouse
Match: Bmp7 (bone morphogenetic protein 7 [Source:MGI Symbol;Acc:MGI:103302])

HSP 1 Score: 126.331 bits (316), Expect = 2.676e-31
Identity = 54/136 (39.71%), Postives = 88/136 (64.71%), Query Frame = 3
Query:  891 NQEESTIPKD-ENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            +Q  S  PK+ E +R+  V  + + D  Q+    C+++ L V+F+++GW  WIIAP+ Y AYYC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  299 SQNRSKTPKNQEALRMASVAENSSSDQRQA----CKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPDTVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH 430          
BLAST of BMP vs. Ensembl Mouse
Match: Bmp2 (bone morphogenetic protein 2 [Source:MGI Symbol;Acc:MGI:88177])

HSP 1 Score: 121.324 bits (303), Expect = 1.000e-29
Identity = 53/119 (44.54%), Postives = 78/119 (65.55%), Query Frame = 3
Query:  936 KRVKRD-KTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            KR KR  K    + L+  C+R+ L V F +VGW+ WI+AP  Y+A+YC G CP+PL+D+ N+TNHAI+Q L++ + +  IPK CCVP  L   ++LYL+     +L+ ++DM V  C C
Sbjct:  276 KREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSV-NSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGC 393          
BLAST of BMP vs. Ensembl Mouse
Match: Bmp4 (bone morphogenetic protein 4 [Source:MGI Symbol;Acc:MGI:88180])

HSP 1 Score: 120.939 bits (302), Expect = 1.647e-29
Identity = 51/120 (42.50%), Postives = 77/120 (64.17%), Query Frame = 3
Query:  930 RLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            R KR  +      +    +C+R+SL V F +VGW+ WI+AP  Y A+YC G+CP+PL+D+ N+TNHAI+Q L++ +   SIPK CCVP  L   ++LYL+     +L+ +++M V  C C
Sbjct:  289 RAKRSPKHHPQRSRKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNS-SIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407          
BLAST of BMP vs. Ensembl Mouse
Match: Bmp4 (bone morphogenetic protein 4 [Source:MGI Symbol;Acc:MGI:88180])

HSP 1 Score: 120.939 bits (302), Expect = 1.647e-29
Identity = 51/120 (42.50%), Postives = 77/120 (64.17%), Query Frame = 3
Query:  930 RLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            R KR  +      +    +C+R+SL V F +VGW+ WI+AP  Y A+YC G+CP+PL+D+ N+TNHAI+Q L++ +   SIPK CCVP  L   ++LYL+     +L+ +++M V  C C
Sbjct:  289 RAKRSPKHHPQRSRKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNS-SIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407          
BLAST of BMP vs. Ensembl Mouse
Match: Bmp8a (bone morphogenetic protein 8a [Source:MGI Symbol;Acc:MGI:104515])

HSP 1 Score: 119.783 bits (299), Expect = 3.545e-29
Identity = 47/102 (46.08%), Postives = 70/102 (68.63%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            C+R+ L V+F+++GW  W+IAPQ Y+AYYC+G C +PL    NATNHAI+Q L+H +K   +PK CC P  L   ++LY +   + +LR+ ++M V +C CH
Sbjct:  298 CRRHELYVSFRDLGWLDWVIAPQGYSAYYCEGECAFPLDSCMNATNHAILQSLVHLMKPDVVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH 399          
BLAST of BMP vs. UniProt/SwissProt
Match: sp|P91699|DECA_DROPS (Protein decapentaplegic OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=dpp PE=2 SV=3)

HSP 1 Score: 130.954 bits (328), Expect = 2.964e-31
Identity = 50/104 (48.08%), Postives = 73/104 (70.19%), Query Frame = 3
Query:  978 EDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            E+ C+R+SL V F +VGW  WI+AP  Y+AYYC G CP+PL+D+FN+TNHA++Q L++ L    +PK CCVP  L    +LYLN +   +L+ +++M+V  C C
Sbjct:  512 EETCRRHSLYVDFADVGWDDWIVAPPGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNLNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 615          
BLAST of BMP vs. UniProt/SwissProt
Match: sp|P07713|DECA_DROME (Protein decapentaplegic OS=Drosophila melanogaster OX=7227 GN=dpp PE=1 SV=2)

HSP 1 Score: 130.568 bits (327), Expect = 3.404e-31
Identity = 49/104 (47.12%), Postives = 73/104 (70.19%), Query Frame = 3
Query:  978 EDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +D C+R+SL V F +VGW  WI+AP  Y+AYYC G CP+PL+D+FN+TNHA++Q L++ +    +PK CCVP  L    +LYLN +   +L+ +++M+V  C C
Sbjct:  484 DDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 587          
BLAST of BMP vs. UniProt/SwissProt
Match: sp|P91706|DECA_DROSI (Protein decapentaplegic OS=Drosophila simulans OX=7240 GN=dpp PE=2 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 3.553e-31
Identity = 49/104 (47.12%), Postives = 73/104 (70.19%), Query Frame = 3
Query:  978 EDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +D C+R+SL V F +VGW  WI+AP  Y+AYYC G CP+PL+D+FN+TNHA++Q L++ +    +PK CCVP  L    +LYLN +   +L+ +++M+V  C C
Sbjct:  489 DDTCRRHSLYVDFSDVGWDDWIVAPLGYDAYYCHGKCPFPLADHFNSTNHAVVQTLVNNMNPGKVPKACCVPTQLDSVAMLYLNDQSTVVLKNYQEMTVVGCGC 592          
BLAST of BMP vs. UniProt/SwissProt
Match: sp|P48970|UNIV_STRPU (Univin OS=Strongylocentrotus purpuratus OX=7668 PE=2 SV=2)

HSP 1 Score: 127.102 bits (318), Expect = 5.385e-31
Identity = 50/107 (46.73%), Postives = 72/107 (67.29%), Query Frame = 3
Query:  972 SLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            SL + CQR+ L V+F++VGW  WIIAP  Y AYYC G CP+PL +  N TNHAIIQ L++ + + ++PK CC P  L   ++LY +   + +LR+++DM V +C C 
Sbjct:  289 SLTNLCQRHRLFVSFRDVGWENWIIAPMGYQAYYCDGECPFPLGERLNGTNHAIIQTLVNSIDNRAVPKVCCAPTKLSGISMLYFDNNENVVLRQYEDMVVEACGCR 395          
BLAST of BMP vs. UniProt/SwissProt
Match: sp|P23359|BMP7_MOUSE (Bone morphogenetic protein 7 OS=Mus musculus OX=10090 GN=Bmp7 PE=1 SV=2)

HSP 1 Score: 126.331 bits (316), Expect = 1.872e-30
Identity = 54/136 (39.71%), Postives = 88/136 (64.71%), Query Frame = 3
Query:  891 NQEESTIPKD-ENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            +Q  S  PK+ E +R+  V  + + D  Q+    C+++ L V+F+++GW  WIIAP+ Y AYYC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  299 SQNRSKTPKNQEALRMASVAENSSSDQRQA----CKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPDTVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH 430          
BLAST of BMP vs. TrEMBL
Match: A8SLH3 (BMP OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 833.173 bits (2151), Expect = 0.000e+0
Identity = 401/401 (100.00%), Postives = 401/401 (100.00%), Query Frame = 3
Query:   90 MQKLIVVNIQILCCFIFKLTQIIDAKDSFYGKRFGSQNNNPSEKVRSNLQKMLLSNMGLQPDDVVDSEKYAELSEKLPHFVPDFMKSLYVKSRYNLFNFSVNIEGKPVHLGPIEIIHCQRLRNIQTWSSVGIHKLVFKSSVYTNDNHPLARELRLNRRLFPKILQEPPNNKSNEMHVIMMIFNEHFQLIKEKPINSKSFMKHGWISVDISEYVKSSVFYIKMYGFWRNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            MQKLIVVNIQILCCFIFKLTQIIDAKDSFYGKRFGSQNNNPSEKVRSNLQKMLLSNMGLQPDDVVDSEKYAELSEKLPHFVPDFMKSLYVKSRYNLFNFSVNIEGKPVHLGPIEIIHCQRLRNIQTWSSVGIHKLVFKSSVYTNDNHPLARELRLNRRLFPKILQEPPNNKSNEMHVIMMIFNEHFQLIKEKPINSKSFMKHGWISVDISEYVKSSVFYIKMYGFWRNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH
Sbjct:    1 MQKLIVVNIQILCCFIFKLTQIIDAKDSFYGKRFGSQNNNPSEKVRSNLQKMLLSNMGLQPDDVVDSEKYAELSEKLPHFVPDFMKSLYVKSRYNLFNFSVNIEGKPVHLGPIEIIHCQRLRNIQTWSSVGIHKLVFKSSVYTNDNHPLARELRLNRRLFPKILQEPPNNKSNEMHVIMMIFNEHFQLIKEKPINSKSFMKHGWISVDISEYVKSSVFYIKMYGFWRNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 401          
BLAST of BMP vs. TrEMBL
Match: D3J1J9 (Bone morphogenetic protein (Fragment) OS=Schmidtea polychroa OX=50054 GN=bmp PE=2 SV=1)

HSP 1 Score: 602.053 bits (1551), Expect = 0.000e+0
Identity = 282/313 (90.10%), Postives = 302/313 (96.49%), Query Frame = 3
Query:  270 PDDVVDSEKYAELSEKLPHFVPDFMKSLYVKSRYNLFNFSVNIEGKPVHLGPIEIIHCQRLRNIQTWSSVGIHKLVFKSSVYTNDNHPLARELRLNRRLFPKILQEPPNNKSNEMHVIMMIFNEHFQLIKEKPINSKSFMKHGWISVDISEYVKSSVFYIKMYGFWRNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRP 1208
            PDDVVDSEKYAELS KLPHFVPDFMKSLYVK RYNLFNFSV+IEGKPVHLGPIEIIHCQRLRNIQTWSSVGIHKLVFKSSVYTNDNHPLARELRLN+RLFPKI+ EPP NKSN +H+IMMIF+EHF+LIKEKPINSKSFMKHGW+S+DISEY+KSS+FYIKMYGFWRN+SSHT+TDLKF I KMNQLYLYYANIVTFY NKAPLPTY + ESTIPK+EN+RLKR+KRDK+ YIQ+LE+DCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRP
Sbjct:    1 PDDVVDSEKYAELSGKLPHFVPDFMKSLYVKYRYNLFNFSVDIEGKPVHLGPIEIIHCQRLRNIQTWSSVGIHKLVFKSSVYTNDNHPLARELRLNKRLFPKIIHEPPKNKSNIVHIIMMIFDEHFKLIKEKPINSKSFMKHGWVSIDISEYMKSSIFYIKMYGFWRNKSSHTTTDLKFHIHKMNQLYLYYANIVTFYTNKAPLPTYKKVESTIPKNENVRLKRIKRDKSSYIQNLEEDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRP 313          
BLAST of BMP vs. TrEMBL
Match: O76147 (Bone morphogenetic protein (Fragment) OS=Dugesia japonica OX=6161 GN=djbmp PE=2 SV=1)

HSP 1 Score: 588.956 bits (1517), Expect = 0.000e+0
Identity = 278/399 (69.67%), Postives = 336/399 (84.21%), Query Frame = 3
Query:   96 KLIVVNIQILCCFIFKLTQIIDAKDSFYGKRFGSQNNNPSEKVRSNLQKMLLSNMGLQPDDVVDSEKYAELSEKLPHFVPDFMKSLYVKSRYNLFNFSVNIEGKPVHLGPIEIIHCQRLRNIQTWSSVGIHKLVFKSSVYTNDNHPLARELRLNRRLFPKILQEPPNNKSNEMHVIMMIFNEHFQLIKEKPINSKSFMKHGWISVDISEYVKSSVFYIKMYGFW-RNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            KL+++NI   C F+FK T+     DSFY K+ G++  NPSEKVRSNLQK+LL NMGL+PD+VVDSE +AELSEKLPHFVPDFMK LYVK R NL+NFSV IEGKP HLGP+E+IHCQRLRNIQTWSSVGIHKL+FKS   +  ++PLARELR+N+RLFP+I+ E PNN+ +E+++I+M+F++ F+L+KEK INSKSF K GWIS+DIS+Y+++SVF+IK +G W +++S     ++K+ IQ+ +QLYLYYANIVTFY NK    +  Q ESTI + EN+ L RVKRD + Y+   E+DCQRY LIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLL+HGLKD+SIPKPCCVPY+L PETLLYLN EGDALLREFKDMSVSSCSC
Sbjct:    1 KLLLINIHFFCYFLFKFTKSNGTSDSFYEKKLGNKITNPSEKVRSNLQKILLLNMGLKPDEVVDSENFAELSEKLPHFVPDFMKLLYVKYRSNLYNFSVEIEGKPKHLGPVEMIHCQRLRNIQTWSSVGIHKLIFKSFTKSKTSYPLARELRINKRLFPRIIHESPNNEFSELYMIIMVFDDRFKLLKEKLINSKSFNKQGWISIDISKYLQNSVFFIKTFGLWKKHKSIFKRVNVKYQIQQSHQLYLYYANIVTFYSNKVRPSSNKQYESTISETENLHLSRVKRDTSGYMPGHEEDCQRYPLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLVHGLKDLSIPKPCCVPYHLHPETLLYLNNEGDALLREFKDMSVSSCSC 399          
BLAST of BMP vs. TrEMBL
Match: A0A3P8LPV9 (TGF_BETA_2 domain-containing protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS13224 PE=3 SV=1)

HSP 1 Score: 132.88 bits (333), Expect = 6.935e-33
Identity = 55/105 (52.38%), Postives = 74/105 (70.48%), Query Frame = 3
Query:  975 LEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            L+  CQR  LI+ F  VGW+ W+IAPQ YNA YC G CP+PLS ++N TNHA++  L+H L    IP PCCVP+ L  ++LLY ++ GD +LR ++DM V SC+C
Sbjct:   63 LDTTCQRRELIINFDAVGWAGWVIAPQAYNARYCLGQCPFPLSTHYNTTNHAVLLQLVHLLDVARIPGPCCVPHQLSSQSLLYHSQNGDVVLRVYEDMVVESCAC 167          
BLAST of BMP vs. TrEMBL
Match: A0A183WM71 (TGF_BETA_2 domain-containing protein OS=Trichobilharzia regenti OX=157069 PE=3 SV=1)

HSP 1 Score: 132.494 bits (332), Expect = 8.177e-33
Identity = 55/105 (52.38%), Postives = 74/105 (70.48%), Query Frame = 3
Query:  975 LEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            L+  CQR  LI+ F  VGW+ W+IAPQ YNA YC G CP+PLS ++N TNHA++  L+H L    IP PCCVP+ L  ++LLY ++ GD +LR ++DM V SC+C
Sbjct:   63 LDTTCQRRELIINFDAVGWAGWVIAPQAYNARYCLGQCPFPLSTHYNTTNHAVLLQLVHLLDVARIPGPCCVPHQLSSQSLLYHSQNGDVVLRVYEDMVVESCAC 167          
BLAST of BMP vs. Ensembl Cavefish
Match: bmp2a (bone morphogenetic protein 2 [Source:NCBI gene;Acc:103021856])

HSP 1 Score: 125.561 bits (314), Expect = 2.377e-31
Identity = 50/102 (49.02%), Postives = 76/102 (74.51%), Query Frame = 3
Query:  984 DCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +C+R+SL V F +VGW+ WI+AP  Y+A+YC+G CP+PL+D+ N+TNHAI+Q L++ + + +IPK CCVP +L P +LLYL+     +L+ ++DM V  C C
Sbjct:  304 NCRRHSLYVDFSDVGWNDWIVAPPGYHAFYCQGECPFPLADHLNSTNHAIVQTLVNSV-NTNIPKACCVPTDLSPVSLLYLDEYERVILKNYQDMVVEGCGC 404          
BLAST of BMP vs. Ensembl Cavefish
Match: bmp2b (Astyanax mexicanus bone morphogenetic protein 2-like (LOC103028976), mRNA. [Source:RefSeq mRNA;Acc:NM_001320207])

HSP 1 Score: 123.635 bits (309), Expect = 1.459e-30
Identity = 58/139 (41.73%), Postives = 85/139 (61.15%), Query Frame = 3
Query:  879 LPTYNQEESTIPKDENIRLKRVKRD--KTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            L TY+ +    P  +  R KR  R   K         +C+R+ L V F +VGW++WI+AP  Y+A+YC G CP+PLSD+ N+TNHAI+Q L++ +   +IP+ CCVP  L P +LLYL+     +L+ ++DM V  C C
Sbjct:  275 LVTYSHDGKGTPLLQPHREKRQARRGPKQRRKPHQRTNCRRHPLYVDFSDVGWNEWIVAPPGYHAFYCNGECPFPLSDHLNSTNHAIVQTLVNSVNS-NIPRACCVPTELSPISLLYLDEYEKVVLKNYQDMVVEGCGC 412          
BLAST of BMP vs. Ensembl Cavefish
Match: bmp2b (Astyanax mexicanus bone morphogenetic protein 2-like (LOC103028976), mRNA. [Source:RefSeq mRNA;Acc:NM_001320207])

HSP 1 Score: 123.635 bits (309), Expect = 2.456e-30
Identity = 58/139 (41.73%), Postives = 85/139 (61.15%), Query Frame = 3
Query:  879 LPTYNQEESTIPKDENIRLKRVKRD--KTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            L TY+ +    P  +  R KR  R   K         +C+R+ L V F +VGW++WI+AP  Y+A+YC G CP+PLSD+ N+TNHAI+Q L++ +   +IP+ CCVP  L P +LLYL+     +L+ ++DM V  C C
Sbjct:  307 LVTYSHDGKGTPLLQPHREKRQARRGPKQRRKPHQRTNCRRHPLYVDFSDVGWNEWIVAPPGYHAFYCNGECPFPLSDHLNSTNHAIVQTLVNSVNS-NIPRACCVPTELSPISLLYLDEYEKVVLKNYQDMVVEGCGC 444          
BLAST of BMP vs. Ensembl Cavefish
Match: bmp4 (bone morphogenetic protein 4 [Source:NCBI gene;Acc:103024384])

HSP 1 Score: 121.709 bits (304), Expect = 5.648e-30
Identity = 50/118 (42.37%), Postives = 76/118 (64.41%), Query Frame = 3
Query:  936 KRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +R KR      +    +C+R++L V F +VGW+ WI+AP  Y AYYC G CP+PL+D+ N+TNHAI+Q L++ +   +IPK CCVP  L   ++LYL+     +L+ +++M V  C C
Sbjct:  285 RRTKRSAKQRGRKRNRNCRRHALYVDFSDVGWNDWIVAPPGYQAYYCHGECPFPLADHLNSTNHAIVQTLVNSVNS-NIPKACCVPTELSAISMLYLDETDRVVLKNYQEMVVEGCGC 401          
BLAST of BMP vs. Ensembl Cavefish
Match: bmp7a (bone morphogenetic protein 7-like [Source:NCBI gene;Acc:103042113])

HSP 1 Score: 121.709 bits (304), Expect = 6.637e-30
Identity = 56/147 (38.10%), Postives = 86/147 (58.50%), Query Frame = 3
Query:  873 APLPTYNQEESTIPK------DENIRLKRVKRD-KTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            AP    NQ  S  PK       E ++L     +   D  Q     C+++ L V+F+++GW  WIIAP+ Y AYYC+G C +PL+   NATNHAI+Q L+H +   S+P+PCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  261 APGHKRNQNRSKAPKHAAPSTQEALKLAEAAENVSVDPKQG----CKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPDSVPRPCCAPTQLHGISVLYFDDSSNVILKKYRNMVVRACGCH 403          
BLAST of BMP vs. Ensembl Sea Lamprey
Match: bmp16 (bone morphogenetic protein 16 [Source:ZFIN;Acc:ZDB-GENE-100115-1])

HSP 1 Score: 125.561 bits (314), Expect = 7.096e-32
Identity = 50/101 (49.50%), Postives = 72/101 (71.29%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            CQR  L V F+EVGW  WI+AP  YNAY+C+G CP+PL+D+ N+TNHAI+Q L++ + + SIP+ CCVP  L P ++LY++     +L+ ++DM V  C C
Sbjct:  328 CQRQPLYVDFREVGWDDWIVAPPGYNAYFCQGECPFPLADHLNSTNHAIVQTLVNSV-NASIPRACCVPTELSPISMLYMDEYEKVVLKNYQDMVVEGCGC 427          
BLAST of BMP vs. Ensembl Sea Lamprey
Match: gdf3 (growth differentiation factor 3 [Source:NCBI gene;Acc:30125])

HSP 1 Score: 123.25 bits (308), Expect = 1.081e-31
Identity = 50/118 (42.37%), Postives = 72/118 (61.02%), Query Frame = 3
Query:  936 KRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +R KR  +    +  + C+R  L V F++VGW  W+IAPQ Y A YC G CPYPL +  N TNHA++Q L+H +    +P+PCCVP +L P ++LY +   + +LR +  M V  C C
Sbjct:  219 RRAKRSASHPPVTPSNVCKRRRLYVDFRDVGWHDWVIAPQGYLANYCAGECPYPLGEALNGTNHAVLQTLVHAVDPRGVPQPCCVPVHLSPISMLYYDNSDNVVLRHYDGMVVDECGC 336          
BLAST of BMP vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011300.1 (pep scaffold:Pmarinus_7.0:GL484183:14786:15094:1 gene:ENSPMAG00000010273.1 transcript:ENSPMAT00000011300.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.457 bits (267), Expect = 1.619e-28
Identity = 44/101 (43.56%), Postives = 65/101 (64.36%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            C R  L V FKE+GW  WIIAP +Y+AY C+G C +PL  +   TNHAIIQ L++ L+  + P  CCVP  L P ++LY++   + + ++++ M V +C C
Sbjct:    1 CGRRQLRVNFKELGWDDWIIAPLDYDAYLCEGACDFPLRSHLEPTNHAIIQTLLNSLEPDATPASCCVPTKLSPISILYIDAGNNVVYKQYEGMVVEACGC 101          
BLAST of BMP vs. Ensembl Sea Lamprey
Match: bmp2a (bone morphogenetic protein 2a [Source:ZFIN;Acc:ZDB-GENE-980526-388])

HSP 1 Score: 112.079 bits (279), Expect = 3.531e-27
Identity = 45/101 (44.55%), Postives = 67/101 (66.34%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            C RY L V F +VGW+ WI+AP  YNA++C+G C +PL  + N+TNHAI+Q L++ + +  +P+ CC+P  L P  LLYL+     +L+ ++DM V  C C
Sbjct:  322 CARYPLYVDFSDVGWNDWIVAPPGYNAFFCQGECHFPLPQHLNSTNHAIVQTLVNSV-NPEVPRACCIPTELTPIALLYLDEYEKVVLKNYQDMVVEGCGC 421          
BLAST of BMP vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006367.1 (pep scaffold:Pmarinus_7.0:GL476771:24172:26941:-1 gene:ENSPMAG00000005753.1 transcript:ENSPMAT00000006367.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 100.523 bits (249), Expect = 2.723e-23
Identity = 43/102 (42.16%), Postives = 62/102 (60.78%), Query Frame = 3
Query:  987 CQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLR-EFKDMSVSSCSC 1289
            C+R  L V+FKE+GW  WIIAP  Y+AY C G C +PL+D+ + T HAI++ L+H      + K CCVP  L   ++LY +  G    + +++ M VS C C
Sbjct:  302 CKRTPLFVSFKEIGWDSWIIAPPGYDAYECTGQCIFPLTDHLSPTKHAIVKTLMHLAHPDKVAKACCVPTKLDSISILYRDEAGVVTYKYKYEGMVVSECGC 403          
BLAST of BMP vs. Ensembl Nematostella
Match: EDO46295 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQJ0])

HSP 1 Score: 123.635 bits (309), Expect = 4.060e-32
Identity = 78/268 (29.10%), Postives = 130/268 (48.51%), Query Frame = 3
Query:  561 RLFPKILQEPPNNKSNEMHVIMM---IFNEH-FQLIKEKPINSKSFMKHGWISVDISEYVKSSVFYIKMYGFWRNRSSHTSTDLKFLIQKMN--QLYLYYANIVTFYGNKAPLP--------------TYNQEESTIPKDENIRLKR----VKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            RL+ +  +  P+N  N  +V+ +   I+      LI ++ + S    + GW   DIS   +           W + S   +  L+  +   N  +L  + A  V F+G K   P              T+      I +    R+ R     +    D   S +  CQR +L V+F+++ W  W+IAP+ Y+A+YC G C +PL+ N NATNHAI+Q L+H +   ++PKPCC P  L P ++LY +++ + +L+++  M V +C CH
Sbjct:   23 RLYKEDTRGDPSNWRNATYVVRLYQVIYPAQVLDLIDQRVLRS---WEKGWQEFDISAAGR----------VW-SESPEKNYGLELSVVNFNNQELSPHLAGFVGFHGLKEKRPFIVSFFKQDGEKKYTHEIHAHDIRQHRATRVSRSLPNAQVGGVDPRASNKKVCQRQALHVSFRKLRWQDWVIAPEGYSAFYCSGECSFPLNANMNATNHAIVQTLVHLMNPKTVPKPCCAPTELSPISVLYFDQDNNVVLKKYNKMVVKACGCH 276          
BLAST of BMP vs. Ensembl Nematostella
Match: EDO47115 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNC2])

HSP 1 Score: 115.161 bits (287), Expect = 8.571e-30
Identity = 68/203 (33.50%), Postives = 101/203 (49.75%), Query Frame = 3
Query:  699 WISVDISEYVK-SSVFYIKMYGFWRNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRL-----KRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            WI+ +++  VK  S +  K YG W +  S+ +    F I    Q+    A I      K     Y          +N ++      R +RD  D +      C+R+ L V F+E+ WS WI+AP+ ++AYYC G CP  +   FN TNHAIIQ L+H     S+P  CCVP  L   ++LY   +G  +L+E+ +M  +SC C
Sbjct:   14 WITFNVTSAVKFWSKYPSKNYGLWVSVRSYQAPPSDFKIATGAQM----AEIQDELQEKKNALNYKVPNVDDLSRDNSKIIMASRTRSRRDVADNL------CRRHRLFVKFQELNWSDWILAPRGFSAYYCTGTCPEVIEQYFNPTNHAIIQNLLHHRYSKSVPAACCVPTRLHSISMLYFELDGSIVLKEYGEMVAASCGC 206          
BLAST of BMP vs. Ensembl Nematostella
Match: EDO39129 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAY4])

HSP 1 Score: 117.857 bits (294), Expect = 3.474e-29
Identity = 54/138 (39.13%), Postives = 82/138 (59.42%), Query Frame = 3
Query:  885 TYNQEE---STIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            TYN +E       +  ++R    KR +  Y       CQR+ L V F +VGW+ WI+AP  Y+A+YC G CPYP++ + NATNHAI+Q +++ + D ++P  CC+P  L P ++L LN     +L+ +KDM +  C C
Sbjct:  247 TYNHDELHHHHTRRKRSLRSGGAKRRRPQY-------CQRHPLYVDFTDVGWNDWIVAPPGYHAFYCTGVCPYPIAKHLNATNHAIVQTIMNTV-DSNVPNACCIPTTLNPISILSLNEFDKVVLKNYKDMVIEGCGC 376          
BLAST of BMP vs. Ensembl Nematostella
Match: EDO31057 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZ10])

HSP 1 Score: 95.9005 bits (237), Expect = 2.194e-21
Identity = 40/97 (41.24%), Postives = 58/97 (59.79%), Query Frame = 3
Query: 1002 LIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYL-NREGDALLREFKDMSVSSCSC 1289
            + V F+ +GWS WIIAPQ Y+AY C+G C YP+ +    TNHA +Q +++ L     PK CC P  L P ++LY  +   + + + +KDM V  C C
Sbjct:  338 MYVDFRLLGWSDWIIAPQGYDAYLCEGECKYPIDNYLRPTNHATVQTIVNSLDPSIAPKACCTPNELSPISILYTEDGSNNVVYKNYKDMVVERCGC 434          
BLAST of BMP vs. Ensembl Nematostella
Match: EDO34888 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN19])

HSP 1 Score: 62.3882 bits (150), Expect = 5.300e-12
Identity = 30/102 (29.41%), Postives = 52/102 (50.98%), Query Frame = 3
Query:  984 DCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            +C R    V+F+E+GW  WI+ P+ +NA YC G+C   +   ++ T       L+   +++S   PCC P  +   +LLY +++ +       +M V  C C
Sbjct:   27 ECCRQEFYVSFEEMGWDNWILVPRGFNANYCTGSCYGHILPVYHHTEVIQKVALLRKQRELS---PCCAPTKMFDLSLLYYDKDENLFQENVSNMVVEECGC 125          
BLAST of BMP vs. Ensembl Medaka
Match: bmp7a (bone morphogenetic protein 7 [Source:NCBI gene;Acc:101160897])

HSP 1 Score: 119.398 bits (298), Expect = 1.115e-31
Identity = 46/112 (41.07%), Postives = 77/112 (68.75%), Query Frame = 3
Query:  957 TDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            +D +   ++ C+++ L V+F+++GW  WIIAP+ Y AYYC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:   34 SDSLGFSKEGCKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLHGISVLYFDDSSNVILKKYRNMVVRACGCH 145          
BLAST of BMP vs. Ensembl Medaka
Match: bmp7a (bone morphogenetic protein 7 [Source:NCBI gene;Acc:101160897])

HSP 1 Score: 122.865 bits (307), Expect = 3.173e-30
Identity = 45/105 (42.86%), Postives = 74/105 (70.48%), Query Frame = 3
Query:  978 EDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            ++ C+++ L V+F+++GW  WIIAP+ Y AYYC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  321 KEGCKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLHGISVLYFDDSSNVILKKYRNMVVRACGCH 425          
BLAST of BMP vs. Ensembl Medaka
Match: bmp7b (bone morphogenetic protein 7 [Source:NCBI gene;Acc:101173146])

HSP 1 Score: 122.094 bits (305), Expect = 4.138e-30
Identity = 53/136 (38.97%), Postives = 86/136 (63.24%), Query Frame = 3
Query:  891 NQEESTIPKD-ENIRLKRVKRDK-TDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            N   S  PK  E +R+  +  +  TD  Q+    C+++ L V+F+++GW  WIIAP+ Y A+YC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  265 NNNRSKNPKSQEALRMANIAENSSTDQKQA----CKKHELYVSFRDLGWQDWIIAPEGYAAFYCEGECAFPLNSYMNATNHAIVQTLVHFIHPDTVPKPCCAPTQLHAISVLYYDDSSNVILKKYRNMVVKACGCH 396          
BLAST of BMP vs. Ensembl Medaka
Match: bmp7b (bone morphogenetic protein 7 [Source:NCBI gene;Acc:101173146])

HSP 1 Score: 122.094 bits (305), Expect = 5.958e-30
Identity = 53/136 (38.97%), Postives = 86/136 (63.24%), Query Frame = 3
Query:  891 NQEESTIPKD-ENIRLKRVKRDK-TDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            N   S  PK  E +R+  +  +  TD  Q+    C+++ L V+F+++GW  WIIAP+ Y A+YC+G C +PL+   NATNHAI+Q L+H +   ++PKPCC P  L   ++LY +   + +L+++++M V +C CH
Sbjct:  296 NNNRSKNPKSQEALRMANIAENSSTDQKQA----CKKHELYVSFRDLGWQDWIIAPEGYAAFYCEGECAFPLNSYMNATNHAIVQTLVHFIHPDTVPKPCCAPTQLHAISVLYYDDSSNVILKKYRNMVVKACGCH 427          
BLAST of BMP vs. Ensembl Medaka
Match: admp (bone morphogenetic protein 2-like [Source:NCBI gene;Acc:101170375])

HSP 1 Score: 120.939 bits (302), Expect = 9.904e-30
Identity = 55/137 (40.15%), Postives = 79/137 (57.66%), Query Frame = 3
Query:  891 NQEESTIPKDENIRLKRVKRDKTDYIQ--SLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDI-SIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
             +  ST+P+              DY +   +   CQR  L V F+E+GWS WI++P+ YNAY+CKG+CP+PL  N   TNHA +Q +I+ LK +  I  PCCVP  L    LLY + + + +L+++ DM   SC CH
Sbjct:  255 GESTSTLPQFPMSSPSSRSARSVDYSEDHGVPKPCQRLPLYVDFEEIGWSGWIVSPRGYNAYHCKGSCPFPLGQNMRPTNHATVQSIINALKLVRGIETPCCVPDKLHSINLLYFDDDENVVLKQYNDMVAGSCGCH 391          
BLAST of BMP vs. Planmine SMEST
Match: SMESG000013937.1 (SMESG000013937.1)

HSP 1 Score: 382.874 bits (982), Expect = 4.033e-133
Identity = 180/180 (100.00%), Postives = 180/180 (100.00%), Query Frame = 3
Query:  753 MYGFWRNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 1292
            MYGFWRNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH
Sbjct:    1 MYGFWRNRSSHTSTDLKFLIQKMNQLYLYYANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH 180          
BLAST of BMP vs. Planmine SMEST
Match: SMESG000059598.1 (SMESG000059598.1)

HSP 1 Score: 92.8189 bits (229), Expect = 5.469e-20
Identity = 50/138 (36.23%), Postives = 75/138 (54.35%), Query Frame = 3
Query:  888 YNQEESTIPKDENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGL---KDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            YN E    PK    R KR    +T D +   +  C  Y + V F ++GW++WII PQ+++A  C G+CPYPL   ++ TNHA++Q + + L    DI  P  CC P+  +   +LY N E    L+ + +M + SC C
Sbjct:  334 YNGEFYVPPK----RFKRSDPSETEDVVVERQKYCFLYPMKVDFDKMGWNQWIIGPQSFSAGICIGSCPYPLGQTYHPTNHAVVQSIWYNLNPNNDIIGPV-CCSPHEFKTLRMLYYNNERVVALKSYDNMIIKSCGC 466          
BLAST of BMP vs. Planmine SMEST
Match: SMESG000059604.1 (SMESG000059604.1)

HSP 1 Score: 92.4337 bits (228), Expect = 6.526e-20
Identity = 50/138 (36.23%), Postives = 75/138 (54.35%), Query Frame = 3
Query:  888 YNQEESTIPKDENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGL---KDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            YN E    PK    R +R    +T D + +    C  Y + V F ++GW +WI+AP ++NA  C G CP+PL  ++  TNHAI+Q + + L    DI  P  CCVP+  +   +L  N +   +L+ F+DM   SC+C
Sbjct:  334 YNGEFYVPPK----RFRRSDSSETKDKVITRRKYCSLYPMQVFFDKMGWDQWIVAPHSFNAGICTGPCPFPLGQSYQPTNHAIVQNIWYNLNPNNDIIGPV-CCVPHEFKTFVILLFNEQA-VVLKSFEDMIAKSCTC 465          
BLAST of BMP vs. Planmine SMEST
Match: SMESG000059598.1 (SMESG000059598.1)

HSP 1 Score: 91.6633 bits (226), Expect = 2.096e-19
Identity = 52/144 (36.11%), Postives = 77/144 (53.47%), Query Frame = 3
Query:  888 YNQEESTIPKDENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGL---KDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSCH*RGYC 1307
            YN E    PK    R KR    +T D +   +  C  Y + V F ++GW++WII PQ+++A  C G+CPYPL   ++ TNHA++Q + + L    DI  P  CC P+  +   +LY N E    L+ + +M + SC     GYC
Sbjct:  334 YNGEFYVPPK----RFKRSDPSETEDVVVERQKYCFLYPMKVDFDKMGWNQWIIGPQSFSAGICIGSCPYPLGQTYHPTNHAVVQSIWYNLNPNNDIIGP-VCCSPHEFKTLRMLYYNNERVVALKSYDNMIIKSC-----GYC 467          
BLAST of BMP vs. Planmine SMEST
Match: SMESG000059596.1 (SMESG000059596.1)

HSP 1 Score: 86.6557 bits (213), Expect = 5.154e-18
Identity = 49/138 (35.51%), Postives = 70/138 (50.72%), Query Frame = 3
Query:  888 YNQEESTIPKDENIRLKRVKRDKT-DYIQSLEDDCQRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQLLIHGL---KDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC 1289
            YN E    PK    R KR    +T D +      C  Y + V F ++GW +WIIAP ++NA  C G CP+PL   +  TNHA++Q + + L    DI  P  CC P+      +L+ N E    L+ + +M + SC C
Sbjct:  329 YNGEFYVPPK----RFKRSDPSETEDVVVERRKYCFLYPMKVYFDKMGWDQWIIAPHSFNAGICIGPCPFPLGQTYYPTNHAVVQSIWYNLNPNNDIIGPV-CCSPHEFTTLRMLFYNNERVVALKSYDNMIIKSCGC 461          
The following BLAST results are available for this feature:
BLAST of BMP vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BMP74.071e-3139.71bone morphogenetic protein 7 [Source:HGNC Symbol;A... [more]
BMP74.501e-3044.12bone morphogenetic protein 7 [Source:HGNC Symbol;A... [more]
BMP45.136e-3043.09bone morphogenetic protein 4 [Source:HGNC Symbol;A... [more]
BMP45.136e-3043.09bone morphogenetic protein 4 [Source:HGNC Symbol;A... [more]
BMP45.136e-3043.09bone morphogenetic protein 4 [Source:HGNC Symbol;A... [more]
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BLAST of BMP vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dbl-17.528e-2941.67DPP/BMP-Like; Decapentaplegic protein homolog [So... [more]
dbl-17.528e-2941.67DPP/BMP-Like; Decapentaplegic protein homolog [So... [more]
tig-27.807e-2434.09TransformIng Growth factor beta family [Source:Un... [more]
unc-1295.592e-1530.69UNC-129 [Source:UniProtKB/TrEMBL;Acc:G5EBY8][more]
unc-1295.592e-1530.69UNC-129 [Source:UniProtKB/TrEMBL;Acc:G5EBY8][more]
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BLAST of BMP vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpp3.396e-3247.12gene:FBgn0000490 transcript:FBtr0077771[more]
dpp3.396e-3247.12gene:FBgn0000490 transcript:FBtr0077773[more]
dpp3.396e-3247.12gene:FBgn0000490 transcript:FBtr0077775[more]
dpp3.396e-3247.12gene:FBgn0000490 transcript:FBtr0077772[more]
gbb1.223e-2746.08gene:FBgn0024234 transcript:FBtr0072127[more]
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BLAST of BMP vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bmp2a3.672e-3148.04bone morphogenetic protein 2a [Source:ZFIN;Acc:ZDB... [more]
gdf34.351e-3044.92growth differentiation factor 3 [Source:NCBI gene;... [more]
bmp44.419e-3042.37bone morphogenetic protein 4 [Source:ZFIN;Acc:ZDB-... [more]
bmp7b4.567e-3037.50bone morphogenetic protein 7b [Source:ZFIN;Acc:ZDB... [more]
bmp7b4.567e-3037.50bone morphogenetic protein 7b [Source:ZFIN;Acc:ZDB... [more]
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BLAST of BMP vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bmp7.11.524e-3241.18bone morphogenetic protein 7, gene 1 [Source:NCBI ... [more]
admp1.600e-3046.22anti-dorsalizing morphogenic protein [Source:NCBI ... [more]
nr5a13.824e-3045.10nuclear receptor subfamily 5 group A member 1 [Sou... [more]
nr5a14.317e-3045.10nuclear receptor subfamily 5 group A member 1 [Sou... [more]
nr5a14.317e-3045.10nuclear receptor subfamily 5 group A member 1 [Sou... [more]
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BLAST of BMP vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Bmp72.676e-3139.71bone morphogenetic protein 7 [Source:MGI Symbol;Ac... [more]
Bmp21.000e-2944.54bone morphogenetic protein 2 [Source:MGI Symbol;Ac... [more]
Bmp41.647e-2942.50bone morphogenetic protein 4 [Source:MGI Symbol;Ac... [more]
Bmp41.647e-2942.50bone morphogenetic protein 4 [Source:MGI Symbol;Ac... [more]
Bmp8a3.545e-2946.08bone morphogenetic protein 8a [Source:MGI Symbol;A... [more]
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BLAST of BMP vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P91699|DECA_DROPS2.964e-3148.08Protein decapentaplegic OS=Drosophila pseudoobscur... [more]
sp|P07713|DECA_DROME3.404e-3147.12Protein decapentaplegic OS=Drosophila melanogaster... [more]
sp|P91706|DECA_DROSI3.553e-3147.12Protein decapentaplegic OS=Drosophila simulans OX=... [more]
sp|P48970|UNIV_STRPU5.385e-3146.73Univin OS=Strongylocentrotus purpuratus OX=7668 PE... [more]
sp|P23359|BMP7_MOUSE1.872e-3039.71Bone morphogenetic protein 7 OS=Mus musculus OX=10... [more]
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BLAST of BMP vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A8SLH30.000e+0100.00BMP OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
D3J1J90.000e+090.10Bone morphogenetic protein (Fragment) OS=Schmidtea... [more]
O761470.000e+069.67Bone morphogenetic protein (Fragment) OS=Dugesia j... [more]
A0A3P8LPV96.935e-3352.38TGF_BETA_2 domain-containing protein OS=Trichobilh... [more]
A0A183WM718.177e-3352.38TGF_BETA_2 domain-containing protein OS=Trichobilh... [more]
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BLAST of BMP vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bmp2a2.377e-3149.02bone morphogenetic protein 2 [Source:NCBI gene;Acc... [more]
bmp2b1.459e-3041.73Astyanax mexicanus bone morphogenetic protein 2-li... [more]
bmp2b2.456e-3041.73Astyanax mexicanus bone morphogenetic protein 2-li... [more]
bmp45.648e-3042.37bone morphogenetic protein 4 [Source:NCBI gene;Acc... [more]
bmp7a6.637e-3038.10bone morphogenetic protein 7-like [Source:NCBI gen... [more]
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BLAST of BMP vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bmp167.096e-3249.50bone morphogenetic protein 16 [Source:ZFIN;Acc:ZDB... [more]
gdf31.081e-3142.37growth differentiation factor 3 [Source:NCBI gene;... [more]
ENSPMAT00000011300.11.619e-2843.56pep scaffold:Pmarinus_7.0:GL484183:14786:15094:1 g... [more]
bmp2a3.531e-2744.55bone morphogenetic protein 2a [Source:ZFIN;Acc:ZDB... [more]
ENSPMAT00000006367.12.723e-2342.16pep scaffold:Pmarinus_7.0:GL476771:24172:26941:-1 ... [more]
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BLAST of BMP vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of BMP vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO462954.060e-3229.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO471158.571e-3033.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO391293.474e-2939.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO310572.194e-2141.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO348885.300e-1229.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of BMP vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bmp7a1.115e-3141.07bone morphogenetic protein 7 [Source:NCBI gene;Acc... [more]
bmp7a3.173e-3042.86bone morphogenetic protein 7 [Source:NCBI gene;Acc... [more]
bmp7b4.138e-3038.97bone morphogenetic protein 7 [Source:NCBI gene;Acc... [more]
bmp7b5.958e-3038.97bone morphogenetic protein 7 [Source:NCBI gene;Acc... [more]
admp9.904e-3040.15bone morphogenetic protein 2-like [Source:NCBI gen... [more]
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BLAST of BMP vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000013937.14.033e-133100.00SMESG000013937.1[more]
SMESG000059598.15.469e-2036.23SMESG000059598.1[more]
SMESG000059604.16.526e-2036.23SMESG000059604.1[more]
SMESG000059598.12.096e-1936.11SMESG000059598.1[more]
SMESG000059596.15.154e-1835.51SMESG000059596.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30014877
GenBankABV04322.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014877 ID=SMED30014877|Name=BMP|organism=Schmidtea mediterranea sexual|type=transcript|length=1471bp
AAAAATTTACAAAAATAGTAATTTTGTTACAATTATTTTTTTCCGGTATT
TTTTTTTTAATTTTTAAATTCGGATAGCGAATACAATTGATGCAAAAATT
AATTGTTGTTAACATACAAATATTATGTTGTTTTATTTTCAAACTCACAC
AAATAATTGATGCCAAAGATTCGTTCTATGGAAAGAGATTCGGTTCACAA
AACAATAATCCATCAGAGAAAGTTCGCAGTAATTTACAGAAAATGCTACT
TTCAAACATGGGACTTCAACCCGATGATGTTGTTGACAGTGAAAAGTATG
CAGAATTGTCGGAAAAATTGCCTCATTTTGTTCCAGATTTTATGAAATCC
CTCTATGTTAAATCCCGATATAATTTGTTTAATTTTTCCGTGAATATCGA
AGGAAAACCTGTACATTTAGGACCTATCGAAATCATACACTGTCAAAGAT
TGAGAAATATTCAAACATGGTCATCCGTTGGTATCCACAAGCTTGTCTTT
AAATCGTCTGTTTATACAAATGACAATCATCCTTTAGCAAGAGAACTCCG
TCTGAATAGAAGATTATTTCCCAAAATACTCCAGGAACCCCCCAATAATA
AATCAAATGAAATGCATGTAATCATGATGATTTTCAATGAGCATTTTCAA
TTAATAAAAGAAAAACCCATCAATTCAAAATCATTTATGAAACATGGTTG
GATTTCAGTAGATATTTCAGAATATGTAAAAAGTTCAGTTTTCTACATTA
AAATGTACGGATTTTGGAGGAATAGGTCATCTCACACAAGTACCGATTTG
AAATTTCTTATACAAAAAATGAATCAACTTTATTTATACTATGCAAATAT
CGTTACATTTTATGGTAATAAAGCTCCTTTGCCTACATATAACCAAGAGG
AATCTACAATTCCTAAAGATGAAAATATTCGTTTAAAGAGAGTTAAACGT
GATAAAACTGATTATATTCAAAGTTTGGAAGATGACTGTCAAAGATATTC
TTTAATTGTTACCTTCAAAGAAGTAGGATGGAGTAAATGGATCATAGCCC
CTCAGAATTACAATGCGTATTATTGCAAAGGTAACTGTCCTTACCCGTTA
TCAGATAATTTTAATGCCACAAACCATGCAATTATTCAATTATTAATTCA
TGGTCTAAAAGACATTTCTATTCCAAAACCGTGCTGTGTGCCCTACAATT
TACGCCCAGAAACCTTGTTATACCTAAACAGGGAAGGAGACGCCTTATTG
AGAGAATTCAAGGATATGTCGGTAAGTAGTTGCTCGTGTCATTGAAGGGG
CTACTGTCACAATTTTCAATCACGATACCTCAAATGTAACTAAGATTTTA
AAACCTAAATGATCATTTTTTTTGCTTTTCTATTTAACTTTCATTTAACT
GAATGTAAAAGTTAAAGTTCTGAAGAATATTTGCATTTTTCATTCTGATT
ATCAAAGTTCTTGTTTTATTT
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protein sequence of SMED30014877-orf-1

>SMED30014877-orf-1 ID=SMED30014877-orf-1|Name=SMED30014877-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=402bp
MQKLIVVNIQILCCFIFKLTQIIDAKDSFYGKRFGSQNNNPSEKVRSNLQ
KMLLSNMGLQPDDVVDSEKYAELSEKLPHFVPDFMKSLYVKSRYNLFNFS
VNIEGKPVHLGPIEIIHCQRLRNIQTWSSVGIHKLVFKSSVYTNDNHPLA
RELRLNRRLFPKILQEPPNNKSNEMHVIMMIFNEHFQLIKEKPINSKSFM
KHGWISVDISEYVKSSVFYIKMYGFWRNRSSHTSTDLKFLIQKMNQLYLY
YANIVTFYGNKAPLPTYNQEESTIPKDENIRLKRVKRDKTDYIQSLEDDC
QRYSLIVTFKEVGWSKWIIAPQNYNAYYCKGNCPYPLSDNFNATNHAIIQ
LLIHGLKDISIPKPCCVPYNLRPETLLYLNREGDALLREFKDMSVSSCSC
H*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000028Category 2 cell
PLANA:0000032dorsal midline
PLANA:0000036eye
PLANA:0000062esophagus
PLANA:0000103central nervous system
PLANA:0000141dorsal region of the whole animal
PLANA:0000418head
PLANA:0002056medial muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR001839TGF-b_C
IPR029034Cystine-knot_cytokine
IPR017948TGFb_CS
Vocabulary: molecular function
TermDefinition
GO:0008083growth factor activity
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region