Netrin receptor DCC

Overview
NameNetrin receptor DCC
Smed IDSMED30014869
Length (bp)3301
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Netrin receptor DCC (SMED30014869) t-SNE clustered cells

Violin plots show distribution of expression levels for Netrin receptor DCC (SMED30014869) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Netrin receptor DCC (SMED30014869) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Netrin receptor DCC (SMED30014869) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014869

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30014869h1SMcG0001017 dd_Smed_v4_7195_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30014869h1SMcG0001017 dd_Smed_v6_7195_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Human
Match: DCC (DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701])

HSP 1 Score: 85.1149 bits (209), Expect = 2.804e-19
Identity = 69/259 (26.64%), Postives = 121/259 (46.72%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            +N I +SW+ P+ P   V+ Y I +G   P      +  K+  + IE L  S++Y + +      G G    +  TT+       P +P V ++ V +     ++SW ++ + KN + S+  ++ V + +     +  +   + +S       + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K             A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:  393 TNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRT-SFSASAKYKSEDTTSLSYTATGLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP-----------RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 637

HSP 2 Score: 31.9574 bits (71), Expect = 2.804e-19
Identity = 17/44 (38.64%), Postives = 23/44 (52.27%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L+L+  YYFRI   N  G  PLS   +F+T     PD+   + G
Sbjct:  647 LNLDTMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDKMANDQG 690
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Human
Match: DCC (DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701])

HSP 1 Score: 77.7962 bits (190), Expect = 8.633e-17
Identity = 70/279 (25.09%), Postives = 122/279 (43.73%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEI---------------VPKI------PVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            +N I +SW+ P+ P   V+ Y I +G   P      +  K+  + IE L  S++Y + +      G G    +  TT+                     VP +      PV ++ V +     ++SW ++ + KN + S+  ++ V + +     +  +   + +S       + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K             A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:  738 TNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRT-SFSASAKYKSEDTTSLSYTATGLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP-----------RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 1002

HSP 2 Score: 30.8018 bits (68), Expect = 8.633e-17
Identity = 17/44 (38.64%), Postives = 23/44 (52.27%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L+L+  YYFRI   N  G  PLS   +F+T     PD+   + G
Sbjct: 1012 LNLDTMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDKMANDQG 1055
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Human
Match: DCC (DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701])

HSP 1 Score: 77.7962 bits (190), Expect = 1.150e-16
Identity = 70/279 (25.09%), Postives = 122/279 (43.73%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEI---------------VPKI------PVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            +N I +SW+ P+ P   V+ Y I +G   P      +  K+  + IE L  S++Y + +      G G    +  TT+                     VP +      PV ++ V +     ++SW ++ + KN + S+  ++ V + +     +  +   + +S       + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K             A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:  715 TNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRT-SFSASAKYKSEDTTSLSYTATGLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP-----------RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 979

HSP 2 Score: 30.4166 bits (67), Expect = 1.150e-16
Identity = 17/44 (38.64%), Postives = 23/44 (52.27%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L+L+  YYFRI   N  G  PLS   +F+T     PD+   + G
Sbjct:  989 LNLDTMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDKMANDQG 1032
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Human
Match: NEO1 (neogenin 1 [Source:HGNC Symbol;Acc:HGNC:7754])

HSP 1 Score: 60.4622 bits (145), Expect = 2.675e-13
Identity = 64/255 (25.10%), Postives = 115/255 (45.10%), Query Frame = 1 
Query: 1267 SIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-KSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIX--XXXXXXXXXXXXSSTVIN--IKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            SI +SW+ P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G   Y   +T      +  P +P V ++   +     +I+W ++ +   ++    I    YY++R       N    N ++T ++  +  + P T YE  V   +    + S +SM    TT E  P+ PP+ +T+ + + K              I V+WQPP + NG+I  Y+I+ + D   ++ +W
Sbjct:  449 SIVVSWTPPENQNIV-VRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQK----ITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSV--MVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPK-----------TIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDW 685

HSP 2 Score: 36.1946 bits (82), Expect = 2.675e-13
Identity = 16/41 (39.02%), Postives = 21/41 (51.22%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNG 2162
            I  L L+  YYF+I   N  G  P+S    F+TP  +G  G
Sbjct:  699 IQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKASGSGG 739
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Human
Match: DCC (DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701])

HSP 1 Score: 63.5438 bits (153), Expect = 9.995e-13
Identity = 38/107 (35.51%), Postives = 56/107 (52.34%), Query Frame = 1 
Query: 1702 NMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
             + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K  P          A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:   48 GLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGK--PR---------AVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 141

HSP 2 Score: 31.5722 bits (70), Expect = 9.995e-13
Identity = 14/30 (46.67%), Postives = 18/30 (60.00%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT 2138
            L+L+  YYFRI   N  G  PLS   +F+T
Sbjct:  151 LNLDTMYYFRIQARNSKGVGPLSDPILFRT 180
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Celegans
Match: unc-40 (Unc-40 protein [Source:UniProtKB/TrEMBL;Acc:G5EF96])

HSP 1 Score: 65.0846 bits (157), Expect = 3.147e-10
Identity = 70/304 (23.03%), Postives = 124/304 (40.79%), Query Frame = 1 
Query: 1165 DKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDI-----------DTVKGIGKS----YVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            D    D E + +   +   P A I         + I +SW  P      V+ Y I WG   P      ++   T++ I  L    +Y + +             +TV+ + +     + +   +   +       PV ++   +  T  ++ W E    + E + NT + V Y +    + N H  +N + T   ++ + PAT YE  VR  + ++ + S +SM     T    PS  P+ LT+       +P++   + +  +  + WQPPK  NGEI+ YL+F T    L   +W    V+G
Sbjct:  726 DTPGQDKEERTLGAPREIRPHAGI---------DYILVSWLPPADEQNLVRGYQIGWGLSVPDTETIRVTASTTQYKIARLHSERDYVISLRAFNNLGSGFPIYETVRTLSRETPSHFNEDSDSDDSDVGSSESTPVGVRAEAISATSIRVMWTE----SDETAFNTQYTVRYST--AVDGNQHRYVNSTETWATVEGLRPATEYEFAVR-AVASNGQLSTWSMATRNRTLAAPPSSAPRDLTV-------LPAE---SGDPHSSSLHWQPPKYSNGEIEEYLVFYTDRASLADKDWTINYVAG 1003
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Fly
Match: fra (gene:FBgn0011592 transcript:FBtr0087821)

HSP 1 Score: 65.0846 bits (157), Expect = 3.584e-10
Identity = 63/266 (23.68%), Postives = 117/266 (43.98%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETK--FVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVP---KIPVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVIN--IKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGK 2025
            +N+I + W  P  P   ++ Y + WG   P   +  I  KET+   ++++L  + +Y V +    VKG G      I T+ E     P   ++PV L+ + +  +   + W +  + KN   + N      +Y++      ++     ++T +N  I ++ P T YE  V+  +V   + S +SM +  +T +  P  PP+ +T+   ++           N   + V W PPK   G+I  Y I+ T D      +W     +G+
Sbjct:  769 ANNIALHWGPPQHPEIKIRNYVLGWGRGIP--DENTIELKETERYHILKNLESNMDYVVSLRARNVKGDGPPIYDNIKTRDEEPVDAPTPLEVPVGLRAITMSSSSIVVYWIDTMLNKNQHVTDN-----RHYTVSYGITGSNRYRYHNTTDLNCMINDLRPNTQYEFAVK--VVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEM-----------NPPTVIVQWIPPKHTLGQITGYNIYYTTDTTKRDRDWSVEAFAGE 1014

HSP 2 Score: 51.9878 bits (123), Expect = 3.986e-6
Identity = 25/41 (60.98%), Postives = 31/41 (75.61%), Query Frame = 3 
Query: 3114 SSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC 3236
            S+D    ++ + S+EEL  EMANLEGLMKDLS+IT  EFEC
Sbjct: 1335 STDEIQRLAPSTSTEELNQEMANLEGLMKDLSAITANEFEC 1375
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Fly
Match: fra (gene:FBgn0011592 transcript:FBtr0087822)

HSP 1 Score: 65.0846 bits (157), Expect = 3.926e-10
Identity = 64/266 (24.06%), Postives = 119/266 (44.74%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETK--FVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVP---KIPVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVIN--IKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGK 2025
            +N+I + W  P  P   ++ Y + WG   P   +  I  KET+   ++++L  + +Y V +    VKG G      I T+ E     P   ++PV L+ + +  +   + W +  + KN   + N      +Y++      ++     ++T +N  I ++ P T YE  V+  +V   + S +SM +  +T +  P  PP+ +T+   ++ N P+          + V W PPK   G+I  Y I+ T D      +W     +G+
Sbjct:  920 ANNIALHWGPPQHPEIKIRNYVLGWGRGIP--DENTIELKETERYHILKNLESNMDYVVSLRARNVKGDGPPIYDNIKTRDEEPVDAPTPLEVPVGLRAITMSSSSIVVYWIDTMLNKNQHVTDN-----RHYTVSYGITGSNRYRYHNTTDLNCMINDLRPNTQYEFAVK--VVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEM-NPPT----------VIVQWIPPKHTLGQITGYNIYYTTDTTKRDRDWSVEAFAGE 1165

HSP 2 Score: 51.9878 bits (123), Expect = 4.020e-6
Identity = 25/41 (60.98%), Postives = 31/41 (75.61%), Query Frame = 3 
Query: 3114 SSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC 3236
            S+D    ++ + S+EEL  EMANLEGLMKDLS+IT  EFEC
Sbjct: 1486 STDEIQRLAPSTSTEELNQEMANLEGLMKDLSAITANEFEC 1526
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Fly
Match: fra (gene:FBgn0011592 transcript:FBtr0339649)

HSP 1 Score: 65.0846 bits (157), Expect = 4.056e-10
Identity = 64/266 (24.06%), Postives = 119/266 (44.74%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETK--FVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVP---KIPVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVIN--IKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGK 2025
            +N+I + W  P  P   ++ Y + WG   P   +  I  KET+   ++++L  + +Y V +    VKG G      I T+ E     P   ++PV L+ + +  +   + W +  + KN   + N      +Y++      ++     ++T +N  I ++ P T YE  V+  +V   + S +SM +  +T +  P  PP+ +T+   ++ N P+          + V W PPK   G+I  Y I+ T D      +W     +G+
Sbjct:  911 ANNIALHWGPPQHPEIKIRNYVLGWGRGIP--DENTIELKETERYHILKNLESNMDYVVSLRARNVKGDGPPIYDNIKTRDEEPVDAPTPLEVPVGLRAITMSSSSIVVYWIDTMLNKNQHVTDN-----RHYTVSYGITGSNRYRYHNTTDLNCMINDLRPNTQYEFAVK--VVKGRRESSWSMSVLNSTYQNVPVTPPREVTVRLDEM-NPPT----------VIVQWIPPKHTLGQITGYNIYYTTDTTKRDRDWSVEAFAGE 1156

HSP 2 Score: 51.9878 bits (123), Expect = 4.051e-6
Identity = 25/41 (60.98%), Postives = 31/41 (75.61%), Query Frame = 3 
Query: 3114 SSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC 3236
            S+D    ++ + S+EEL  EMANLEGLMKDLS+IT  EFEC
Sbjct: 1477 STDEIQRLAPSTSTEELNQEMANLEGLMKDLSAITANEFEC 1517
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Fly
Match: Ptp69D (gene:FBgn0014007 transcript:FBtr0075914)

HSP 1 Score: 57.3806 bits (137), Expect = 7.897e-8
Identity = 87/354 (24.58%), Postives = 138/354 (38.98%), Query Frame = 1 
Query: 1012 LDKISSFSQL----LNVTNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWS-----QPIVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGK--SYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKIS--WNE------DYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDN--WGER 2010
            LD  SS S+L    LN T    ++  + +  ++C + D   L + S                  K+I L    +P+ SI  F     +N I ++W+      PI          G       K  I+G  T ++++   P+T YF++I      G G+   Y Q ITT   +   +PK+         G T + I+  WN       DYI+  E     +   E   +         + N  +       +  AT YE  VR C   +  C  +S  +  TT +   + P    T  ++Q  +   DN    N  AI  +W  PK PNG++ +YLI +  +    VD   WG +
Sbjct:  181 LDTFSSISKLNDTHLNFTLEFTEVYKKENGTYKCTVFDDTGLEITS------------------KEITLFVMEVPQVSID-FAKAVGANKIYLNWTVNDGNDPIQKFFITLQEAGTPTFTYHKDFINGSHTSYILDHFKPNTTYFLRIVGKNSIGNGQPTQYPQGITTLSYDPIFIPKVET------TGSTASTITIGWNPPPPDLIDYIQYYE-----LIVSESGEVPKVIEEAIYQQNSRNLPYMFDKLKTATDYEFRVRACSDLTKTCGPWSENVNGTTMDGVATKP----TNLSIQCHH---DNVTRGNSIAI--NWDVPKTPNGKVVSYLIHLLGNPMSTVDREMWGPK 495
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Fly
Match: Ptp69D (gene:FBgn0014007 transcript:FBtr0075913)

HSP 1 Score: 57.3806 bits (137), Expect = 8.101e-8
Identity = 87/354 (24.58%), Postives = 138/354 (38.98%), Query Frame = 1 
Query: 1012 LDKISSFSQL----LNVTNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWS-----QPIVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGK--SYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKIS--WNE------DYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDN--WGER 2010
            LD  SS S+L    LN T    ++  + +  ++C + D   L + S                  K+I L    +P+ SI  F     +N I ++W+      PI          G       K  I+G  T ++++   P+T YF++I      G G+   Y Q ITT   +   +PK+         G T + I+  WN       DYI+  E     +   E   +         + N  +       +  AT YE  VR C   +  C  +S  +  TT +   + P    T  ++Q  +   DN    N  AI  +W  PK PNG++ +YLI +  +    VD   WG +
Sbjct:  181 LDTFSSISKLNDTHLNFTLEFTEVYKKENGTYKCTVFDDTGLEITS------------------KEITLFVMEVPQVSID-FAKAVGANKIYLNWTVNDGNDPIQKFFITLQEAGTPTFTYHKDFINGSHTSYILDHFKPNTTYFLRIVGKNSIGNGQPTQYPQGITTLSYDPIFIPKVET------TGSTASTITIGWNPPPPDLIDYIQYYE-----LIVSESGEVPKVIEEAIYQQNSRNLPYMFDKLKTATDYEFRVRACSDLTKTCGPWSENVNGTTMDGVATKP----TNLSIQCHH---DNVTRGNSIAI--NWDVPKTPNGKVVSYLIHLLGNPMSTVDREMWGPK 495
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Zebrafish
Match: neo1a (neogenin 1a [Source:ZFIN;Acc:ZDB-GENE-021031-1])

HSP 1 Score: 71.633 bits (174), Expect = 4.906e-16
Identity = 67/272 (24.63%), Postives = 124/272 (45.59%), Query Frame = 1 
Query: 1204 LKKRSIPEASITTFEFISTSNSIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-KSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            L +  +P+   ++    S  NSI +SW+ P    IV V+ Y+I++G   P      +  K+  + IE+L P+++Y + +      G G   Y   IT  +   + +P +P V ++   +     K++W ++ +   ++  +  +    +      N      N ++    +  + P T YE  V   +    + S +SM    TT E+ PS PP+ +T+  V  +  P           I V+WQPP + NG+I  Y+I+ + D K +V +W
Sbjct:  712 LDESRVPDVP-SSLHVRSLVNSIVVSWTPPENQDIV-VRGYSISYGIGSPHAQTIKVDYKQRYYTIENLNPNSHYVITLKAFNNVGEGIPVYESAITRPQSVPDPIPMLPPVGVQASVLNQDTIKVTWADNSLPKNQKITDARYYTVRWKTNIPANTKFKVANTTTLFHTVTGLKPNTLYEFSV--MVTKGRRTSTWSMTAHGTTFESIPSSPPKDVTV--VSKEGRPK---------TIIVNWQPPSEANGKITGYIIYYSTDVKAEVHDW 968

HSP 2 Score: 33.8834 bits (76), Expect = 4.906e-16
Identity = 18/46 (39.13%), Postives = 22/46 (47.83%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENG---KNGGP 2168
            I  L L+  YYF+I   N  G  P+S    F+TP   G   K G P
Sbjct:  982 IQELTLDTTYYFKIQARNSKGMGPMSEAVQFRTPKAPGISVKQGRP 1027
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Zebrafish
Match: neo1a (neogenin 1a [Source:ZFIN;Acc:ZDB-GENE-021031-1])

HSP 1 Score: 71.633 bits (174), Expect = 4.423e-15
Identity = 65/271 (23.99%), Postives = 123/271 (45.39%), Query Frame = 1 
Query: 1204 LKKRSIPEASITTFEFISTSNSIKISWSQPI---VPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-KSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            L +  +P+   ++    S  NSI +SW+ P    + V+ Y+I++G   P      +  K+  + IE+L P+++Y + +      G G   Y   IT  +   + +P +P V ++   +     K++W ++ +   ++  +  +    +      N      N ++    +  + P T YE  V   +    + S +SM    TT E+ PS PP+ +T+  V  +  P           I V+WQPP + NG+I  Y+I+ + D K +V +W
Sbjct:  712 LDESRVPDVP-SSLHVRSLVNSIVVSWTPPENQDIVVRGYSISYGIGSPHAQTIKVDYKQRYYTIENLNPNSHYVITLKAFNNVGEGIPVYESAITRPQSVPDPIPMLPPVGVQASVLNQDTIKVTWADNSLPKNQKITDARYYTVRWKTNIPANTKFKVANTTTLFHTVTGLKPNTLYEFSV--MVTKGRRTSTWSMTAHGTTFESIPSSPPKDVTV--VSKEGRPK---------TIIVNWQPPSEANGKITGYIIYYSTDVKAEVHDW 968

HSP 2 Score: 30.8018 bits (68), Expect = 4.423e-15
Identity = 14/34 (41.18%), Postives = 18/34 (52.94%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            I  L L+  YYF+I   N  G  P+S    F+TP
Sbjct:  982 IQELTLDTTYYFKIQARNSKGMGPMSEAVQFRTP 1015
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Zebrafish
Match: dcc (DCC netrin 1 receptor [Source:NCBI gene;Acc:569360])

HSP 1 Score: 72.7886 bits (177), Expect = 6.056e-15
Identity = 70/265 (26.42%), Postives = 119/265 (44.91%), Query Frame = 1 
Query: 1264 NSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNY----FVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVI----NIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            NSI +SW+ P+ P   ++ YTI +G   P      +  K+  + IE+L PS       F   D              + T   +    P IP V ++ V +     ++SW ++ I   ++S     +V YYS++ + +++ +  + S+        +  + P T YE  V   +    K S +SM    TT E  PS  P+ LT+  +  +  P          AI +SWQPP + NG I  ++++ T +K L +D+W    +SG
Sbjct:  724 NSIIMSWTPPLNPNTLIRGYTIGYGVGSPYAQTVRVDSKQRYYSIENLDPSDPSDDDLFHLFDN-------------VATAAPDSSSAPMIPPVGVQAVALTSDSVRVSWADNSIPKNQKSS----EVRYYSVKWRTSHSTSGKHKSADTTALSHTVTGLKPNTMYEFSV--MVTKGRKSSTWSMTAHATTYEAAPSSAPKDLTV--IGREGRPR---------AILISWQPPLEANGRITGFILYYTLEKNLPIDDWVMEPISG 958

HSP 2 Score: 28.8758 bits (63), Expect = 6.056e-15
Identity = 18/48 (37.50%), Postives = 25/48 (52.08%), Query Frame = 3 
Query: 2037 VIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            V+D L+L+  YYFRI   N  G  PLS    ++T     PD+   + G
Sbjct:  965 VLD-LNLDTVYYFRIQAKNAKGVGPLSDPVQYRTSKVEHPDKMANDQG 1011
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Zebrafish
Match: neo1a (neogenin 1a [Source:ZFIN;Acc:ZDB-GENE-021031-1])

HSP 1 Score: 67.0106 bits (162), Expect = 1.149e-13
Identity = 64/290 (22.07%), Postives = 123/290 (42.41%), Query Frame = 1 
Query: 1204 LKKRSIPEASITTFEFISTSNSIKISWSQPI---VPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKI---------------------PVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            L +  +P+   ++    S  NSI +SW+ P    + V+ Y+I++G   P      +  K+  + IE+L P+++Y + +      G G    +   T+ ++  I P +                     PV ++   +     K++W ++ +   ++  +  +    +      N      N ++    +  + P T YE  V   +    + S +SM    TT E+ PS PP+ +T+  V  +  P           I V+WQPP + NG+I  Y+I+ + D K +V +W
Sbjct:  712 LDESRVPDVP-SSLHVRSLVNSIVVSWTPPENQDIVVRGYSISYGIGSPHAQTIKVDYKQRYYTIENLNPNSHYVITLKAFNNVGEGIPVYESAITRPQSDPIDPDVDLYELFHAPYTPVPDPIPMLPPVGVQASVLNQDTIKVTWADNSLPKNQKITDARYYTVRWKTNIPANTKFKVANTTTLFHTVTGLKPNTLYEFSV--MVTKGRRTSTWSMTAHGTTFESIPSSPPKDVTV--VSKEGRPK---------TIIVNWQPPSEANGKITGYIIYYSTDVKAEVHDW 987

HSP 2 Score: 30.4166 bits (67), Expect = 1.149e-13
Identity = 14/34 (41.18%), Postives = 18/34 (52.94%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            I  L L+  YYF+I   N  G  P+S    F+TP
Sbjct: 1001 IQELTLDTTYYFKIQARNSKGMGPMSEAVQFRTP 1034
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Zebrafish
Match: neo1b (neogenin 1b [Source:ZFIN;Acc:ZDB-GENE-131121-320])

HSP 1 Score: 62.3882 bits (150), Expect = 8.633e-12
Identity = 65/262 (24.81%), Postives = 116/262 (44.27%), Query Frame = 1 
Query: 1264 NSIKISWSQPI---VPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENK-EIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIX----XXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            N I +SW+ P    V V+ Y I +G   P      +  K+  + I++L  S++Y + +      G G       TT+ ++  +  P +P V ++   +     K+SW ++ +   ++    I    YY+IR       N  +   N +S    +  + P T YE  V   +  + + S +SM    TT E+ PS  P+ +T+ + +            N   I ++WQPP + NG+I  Y+I+ + D   +V +W    V G
Sbjct:  752 NRIVVSWTPPENQEVLVRGYKIGYGIGSPHAHTVTLDYKQRFYSIDNLDASSHYVITLKAYNNMGEGVPIYNSATTRPQSAPDPTPMLPPVGVQASVLSHDTVKVSWADNSLAKNQK----ITDARYYTIRWKTNIPANTKYKMANTTSLFHTVSALKPNTLYEFSV--MVTKNRRSSTWSMTAHSTTHESIPSSAPKDVTVISKE-----------GNPRIININWQPPTEANGKITGYIIYYSTDVNAEVHDWVVEPVVG 996

HSP 2 Score: 28.4906 bits (62), Expect = 8.633e-12
Identity = 13/34 (38.24%), Postives = 18/34 (52.94%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            I  L L+  Y+F+I   N  G  P+S    F+TP
Sbjct: 1003 IQGLTLDTSYFFKIQARNSKGMGPMSDAVQFRTP 1036
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Xenopus
Match: DCC (DCC netrin 1 receptor [Source:NCBI gene;Acc:100486082])

HSP 1 Score: 95.5153 bits (236), Expect = 2.929e-22
Identity = 68/258 (26.36%), Postives = 122/258 (47.29%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            + SI +SW+ P+ P   V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G    +  TT+ +     P +P V ++ V +     ++SW ++ +   +++    F    +      ++ +   + +S    +  + P T YE  V   +    + S +SM    TT ET P+  P+ LT+ T + K             A+ VSWQPP + NG+I +Y++F T DK L +D+W   T++G
Sbjct:  726 TTSIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIENLEPSSHYVISLKAFNNAGEGVPLYESATTRSQTDMSTPMLPPVGVQAVALTHDAVRVSWADNSVIKNQKTAEVRFYTIRWRTSYSASSKYKSADTTSLSHTVTGLKPNTMYEFSV--MVTKGRRSSTWSMTAHATTYETAPTSAPKDLTVITRERKP-----------RAVIVSWQPPIEANGKIIDYILFYTLDKNLQIDDWVMVTITG 970

HSP 2 Score: 31.9574 bits (71), Expect = 2.929e-22
Identity = 15/31 (48.39%), Postives = 18/31 (58.06%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            L+L+  YYFRI   N  G  PLS    F+TP
Sbjct:  980 LNLDTAYYFRIQARNAKGLGPLSDPITFRTP 1010
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Xenopus
Match: DCC (DCC netrin 1 receptor [Source:NCBI gene;Acc:100486082])

HSP 1 Score: 91.6633 bits (226), Expect = 1.264e-21
Identity = 69/263 (26.24%), Postives = 123/263 (46.77%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKI------PVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            + SI +SW+ P+ P   V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G    +  TT+ +    VP +      PV ++ V +     ++SW ++ +   +++    F    +      ++ +   + +S    +  + P T YE  V   +    + S +SM    TT ET P+  P+ LT+ T + K             A+ VSWQPP + NG+I +Y++F T DK L +D+W   T++G
Sbjct:  738 TTSIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIENLEPSSHYVISLKAFNNAGEGVPLYESATTRSQT---VPDMSTPMLPPVGVQAVALTHDAVRVSWADNSVIKNQKTAEVRFYTIRWRTSYSASSKYKSADTTSLSHTVTGLKPNTMYEFSV--MVTKGRRSSTWSMTAHATTYETAPTSAPKDLTVITRERKP-----------RAVIVSWQPPIEANGKIIDYILFYTLDKNLQIDDWVMVTITG 984

HSP 2 Score: 33.4982 bits (75), Expect = 1.264e-21
Identity = 16/33 (48.48%), Postives = 19/33 (57.58%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDE 2147
            L+L+  YYFRI   N  G  PLS    F+TP E
Sbjct:  994 LNLDTAYYFRIQARNAKGLGPLSDPITFRTPKE 1026
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Xenopus
Match: DCC (DCC netrin 1 receptor [Source:NCBI gene;Acc:100486082])

HSP 1 Score: 90.5077 bits (223), Expect = 2.672e-21
Identity = 69/263 (26.24%), Postives = 123/263 (46.77%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKI------PVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            + SI +SW+ P+ P   V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G    +  TT+ +    VP +      PV ++ V +     ++SW ++ +   +++    F    +      ++ +   + +S    +  + P T YE  V   +    + S +SM    TT ET P+  P+ LT+ T + K             A+ VSWQPP + NG+I +Y++F T DK L +D+W   T++G
Sbjct:  742 TTSIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIENLEPSSHYVISLKAFNNAGEGVPLYESATTRSQT---VPDMSTPMLPPVGVQAVALTHDAVRVSWADNSVIKNQKTAEVRFYTIRWRTSYSASSKYKSADTTSLSHTVTGLKPNTMYEFSV--MVTKGRRSSTWSMTAHATTYETAPTSAPKDLTVITRERKP-----------RAVIVSWQPPIEANGKIIDYILFYTLDKNLQIDDWVMVTITG 988

HSP 2 Score: 33.113 bits (74), Expect = 2.672e-21
Identity = 16/36 (44.44%), Postives = 20/36 (55.56%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGK 2156
            L+L+  YYFRI   N  G  PLS    F+TP  N +
Sbjct:  998 LNLDTAYYFRIQARNAKGLGPLSDPITFRTPKGNSQ 1033
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Xenopus
Match: DCC (DCC netrin 1 receptor [Source:NCBI gene;Acc:100486082])

HSP 1 Score: 87.4261 bits (215), Expect = 2.841e-20
Identity = 70/280 (25.00%), Postives = 124/280 (44.29%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEI-----------------VPKI------PVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            + SI +SW+ P+ P   V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G    +  TT+ +   I                 VP +      PV ++ V +     ++SW ++ +   +++    F    +      ++ +   + +S    +  + P T YE  V   +    + S +SM    TT ET P+  P+ LT+ T + K             A+ VSWQPP + NG+I +Y++F T DK L +D+W   T++G
Sbjct:  720 TTSIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIENLEPSSHYVISLKAFNNAGEGVPLYESATTRSQTDPIDPLEIEFYPFIDDFPTSVPDMSTPMLPPVGVQAVALTHDAVRVSWADNSVIKNQKTAEVRFYTIRWRTSYSASSKYKSADTTSLSHTVTGLKPNTMYEFSV--MVTKGRRSSTWSMTAHATTYETAPTSAPKDLTVITRERKP-----------RAVIVSWQPPIEANGKIIDYILFYTLDKNLQIDDWVMVTITG 986

HSP 2 Score: 33.113 bits (74), Expect = 2.841e-20
Identity = 16/36 (44.44%), Postives = 20/36 (55.56%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGK 2156
            L+L+  YYFRI   N  G  PLS    F+TP  N +
Sbjct:  996 LNLDTAYYFRIQARNAKGLGPLSDPITFRTPKGNSQ 1031
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Xenopus
Match: DCC (DCC netrin 1 receptor [Source:NCBI gene;Acc:100486082])

HSP 1 Score: 87.4261 bits (215), Expect = 7.113e-20
Identity = 70/280 (25.00%), Postives = 124/280 (44.29%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEI-----------------VPKI------PVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            + SI +SW+ P+ P   V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G    +  TT+ +   I                 VP +      PV ++ V +     ++SW ++ +   +++    F    +      ++ +   + +S    +  + P T YE  V   +    + S +SM    TT ET P+  P+ LT+ T + K             A+ VSWQPP + NG+I +Y++F T DK L +D+W   T++G
Sbjct:  738 TTSIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIENLEPSSHYVISLKAFNNAGEGVPLYESATTRSQTDPIDPLEIEFYPFIDDFPTSVPDMSTPMLPPVGVQAVALTHDAVRVSWADNSVIKNQKTAEVRFYTIRWRTSYSASSKYKSADTTSLSHTVTGLKPNTMYEFSV--MVTKGRRSSTWSMTAHATTYETAPTSAPKDLTVITRERKP-----------RAVIVSWQPPIEANGKIIDYILFYTLDKNLQIDDWVMVTITG 1004

HSP 2 Score: 31.5722 bits (70), Expect = 7.113e-20
Identity = 15/31 (48.39%), Postives = 18/31 (58.06%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            L+L+  YYFRI   N  G  PLS    F+TP
Sbjct: 1014 LNLDTAYYFRIQARNAKGLGPLSDPITFRTP 1044
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Mouse
Match: Dcc (deleted in colorectal carcinoma [Source:MGI Symbol;Acc:MGI:94869])

HSP 1 Score: 86.6557 bits (213), Expect = 4.025e-19
Identity = 65/258 (25.19%), Postives = 116/258 (44.96%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            +N I +SW+ P+ P   V+ Y I +G   P      +  K+  + IE L  S++Y + +      G G    +  TT+       P +P V ++ V +     ++SW ++ +   +++ +       +      +  +   + +S       + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K             A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:  738 TNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP-----------RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 982

HSP 2 Score: 29.261 bits (64), Expect = 4.025e-19
Identity = 17/44 (38.64%), Postives = 22/44 (50.00%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L L+  YYFRI   N  G  PLS   +F+T     PD+   + G
Sbjct:  992 LSLDTMYYFRIQARNVKGVGPLSDPILFRTLKVEHPDKMANDQG 1035
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Mouse
Match: Dcc (deleted in colorectal carcinoma [Source:MGI Symbol;Acc:MGI:94869])

HSP 1 Score: 77.0258 bits (188), Expect = 3.111e-16
Identity = 65/278 (23.38%), Postives = 115/278 (41.37%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVP---------------------KIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            +N I +SW+ P+ P   V+ Y I +G   P      +  K+  + IE L  S++Y + +      G G    +  TT+       P                       PV ++ V +     ++SW ++ +   +++ +       +      +  +   + +S       + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K             A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:  738 TNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP-----------RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 1002

HSP 2 Score: 29.261 bits (64), Expect = 3.111e-16
Identity = 17/44 (38.64%), Postives = 22/44 (50.00%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L L+  YYFRI   N  G  PLS   +F+T     PD+   + G
Sbjct: 1012 LSLDTMYYFRIQARNVKGVGPLSDPILFRTLKVEHPDKMANDQG 1055
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Mouse
Match: Neo1 (neogenin [Source:MGI Symbol;Acc:MGI:1097159])

HSP 1 Score: 59.3066 bits (142), Expect = 9.310e-12
Identity = 63/255 (24.71%), Postives = 114/255 (44.71%), Query Frame = 1 
Query: 1267 SIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-KSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIX--XXXXXXXXXXXXSSTVIN--IKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            SI +SW+ P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G   Y   +T      +  P +P V ++   +     +I+W ++ +   ++    I    YY++R       N    N ++T ++  +  + P T YE  V   +    + S +SM     T E  P+ PP+ +T+ + + K              I V+WQPP + NG+I  Y+I+ + D   ++ +W
Sbjct:  784 SIVVSWTPPENQNIV-VRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQK----ITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSV--MVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKP-----------RTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDW 1020

HSP 2 Score: 31.5722 bits (70), Expect = 9.310e-12
Identity = 16/41 (39.02%), Postives = 20/41 (48.78%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNG 2162
            I  L L+  YYF+I   N  G  P+S    F+TP   G  G
Sbjct: 1034 IQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKALGSAG 1074
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Mouse
Match: Neo1 (neogenin [Source:MGI Symbol;Acc:MGI:1097159])

HSP 1 Score: 53.9138 bits (128), Expect = 1.627e-10
Identity = 65/271 (23.99%), Postives = 115/271 (42.44%), Query Frame = 1 
Query: 1267 SIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-----KSYVQPITTKKE------NKEIVP-------KIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIX--XXXXXXXXXXXXSSTVIN--IKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            SI +SW+ P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G      +  +P T   E      N    P         PV ++   +     +I+W ++ +   ++    I    YY++R       N    N ++T ++  +  + P T YE  V   +    + S +SM     T E  P+ PP+ +T+ + + K              I V+WQPP + NG+I  Y+I+ + D   ++ +W
Sbjct:  784 SIVVSWTPPENQNIV-VRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQK----ITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSV--MVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKP-----------RTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDW 1036

HSP 2 Score: 32.7278 bits (73), Expect = 1.627e-10
Identity = 15/43 (34.88%), Postives = 21/43 (48.84%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGP 2168
            I  L L+  YYF+I   N  G  P+S    F+TP  +  +  P
Sbjct: 1050 IQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMP 1092
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Mouse
Match: Ptprq (protein tyrosine phosphatase, receptor type, Q [Source:MGI Symbol;Acc:MGI:1096349])

HSP 1 Score: 54.6842 bits (130), Expect = 8.929e-7
Identity = 63/253 (24.90%), Postives = 111/253 (43.87%), Query Frame = 1 
Query: 1234 ITTFEFISTSNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSS--TVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTAD 1977
            I TF+ +S S SI +SW  P+ P   + +Y +     +   + +         V+E L+P T Y       T+KG+G S +    T  E+  + P  P NL L+     +  ++W+   +  G      I +V  + I     +     N+S   T   +  + P +TY I V +        + +S V++FTTQE+ P             ++N+     + ++  ++ V W PP+K NG I +Y+I V  +
Sbjct: 1157 INTFKNLS-STSILLSWDPPLKPNGAILSYHLTLQGTH---ANRTFVTSGNHIVLEELSPFTLYSFLAAARTMKGLGPSSILFFYTD-ESAPLAP--PQNLTLINYTSDFVWLTWSPSPLPGG------IVKVYSFKIHEHETDTVFYKNISGFQTDAKLAGLEPVSTYSISV-SAFTKVGNGNQFSNVVKFTTQESVPD-----------AVQNI---ACVARDWQSVSVMWDPPRKANGIIIHYMITVEGN 1381
[Close]
BLAST of Netrin receptor DCC vs. UniProt/SwissProt
Match: sp|P43146|DCC_HUMAN (Netrin receptor DCC OS=Homo sapiens OX=9606 GN=DCC PE=1 SV=2)

HSP 1 Score: 77.7962 bits (190), Expect = 3.818e-16
Identity = 70/279 (25.09%), Postives = 122/279 (43.73%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEI---------------VPKI------PVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            +N I +SW+ P+ P   V+ Y I +G   P      +  K+  + IE L  S++Y + +      G G    +  TT+                     VP +      PV ++ V +     ++SW ++ + KN + S+  ++ V + +     +  +   + +S       + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K             A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:  738 TNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRT-SFSASAKYKSEDTTSLSYTATGLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP-----------RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 1002

HSP 2 Score: 30.8018 bits (68), Expect = 3.818e-16
Identity = 17/44 (38.64%), Postives = 23/44 (52.27%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L+L+  YYFRI   N  G  PLS   +F+T     PD+   + G
Sbjct: 1012 LNLDTMYYFRIQARNSKGVGPLSDPILFRTLKVEHPDKMANDQG 1055
[Close]
BLAST of Netrin receptor DCC vs. UniProt/SwissProt
Match: sp|Q63155|DCC_RAT (Netrin receptor DCC OS=Rattus norvegicus OX=10116 GN=Dcc PE=1 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 1.461e-15
Identity = 65/278 (23.38%), Postives = 115/278 (41.37%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVP---------------------KIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            +N I +SW+ P+ P   V+ Y I +G   P      +  K+  + IE L  S++Y + +      G G    +  TT+       P                       PV ++ V +     ++SW ++ +   +++ +       +      +  +   + +S       + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K             A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:  738 TNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP-----------RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 1002

HSP 2 Score: 29.6462 bits (65), Expect = 1.461e-15
Identity = 17/44 (38.64%), Postives = 22/44 (50.00%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L L+  YYFRI   N  G  PLS   +F+T     PD+   + G
Sbjct: 1012 LSLDTMYYFRIQARNAKGVGPLSDPILFRTLKVEHPDKMANDQG 1055
[Close]
BLAST of Netrin receptor DCC vs. UniProt/SwissProt
Match: sp|P70211|DCC_MOUSE (Netrin receptor DCC OS=Mus musculus OX=10090 GN=Dcc PE=1 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 1.899e-15
Identity = 65/278 (23.38%), Postives = 115/278 (41.37%), Query Frame = 1 
Query: 1261 SNSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVP---------------------KIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            +N I +SW+ P+ P   V+ Y I +G   P      +  K+  + IE L  S++Y + +      G G    +  TT+       P                       PV ++ V +     ++SW ++ +   +++ +       +      +  +   + +S       + P T YE  V   +  + + S +SM    TT E  P+  P+ LT+ T + K             A+ VSWQPP + NG+I  Y++F T DK + +D+W   T+SG
Sbjct:  738 TNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSV--MVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKP-----------RAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISG 1002

HSP 2 Score: 29.261 bits (64), Expect = 1.899e-15
Identity = 17/44 (38.64%), Postives = 22/44 (50.00%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L L+  YYFRI   N  G  PLS   +F+T     PD+   + G
Sbjct: 1012 LSLDTMYYFRIQARNVKGVGPLSDPILFRTLKVEHPDKMANDQG 1055
[Close]
BLAST of Netrin receptor DCC vs. UniProt/SwissProt
Match: sp|Q90610|NEO1_CHICK (Neogenin (Fragment) OS=Gallus gallus OX=9031 PE=2 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 2.963e-10
Identity = 65/273 (23.81%), Postives = 116/273 (42.49%), Query Frame = 1 
Query: 1267 SIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG----KSYV----------------QPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVIN----IKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            SI +SW+ P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G    +S V                 P T   +   ++P  PV ++   +     +I+W ++ +   ++    I    YY++R + N   N    ++        +  + P T YE  V   +    + S +SM    TT E  P+ PP+ +T+ + + K              I V+WQPP + NG+I  Y+I+ + D   ++ +W
Sbjct:  738 SIVVSWTPPENQNIV-VRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHSDTSEVDLFVINAPYTPVPDPSPMMP--PVGVQASILSHDTIRITWADNSLPKNQK----ITDARYYTVRWKTNIPANTKYKTANATTLSYLVTGLKPNTLYEFSV--MVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKP-----------RTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDW 990

HSP 2 Score: 31.9574 bits (71), Expect = 2.963e-10
Identity = 15/43 (34.88%), Postives = 20/43 (46.51%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGP 2168
            I  L L+  YYF+I   N  G  P+S    F+TP     +  P
Sbjct: 1004 IQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKAESSDKMP 1046
[Close]
BLAST of Netrin receptor DCC vs. UniProt/SwissProt
Match: sp|Q92859|NEO1_HUMAN (Neogenin OS=Homo sapiens OX=9606 GN=NEO1 PE=1 SV=2)

HSP 1 Score: 55.4546 bits (132), Expect = 3.780e-10
Identity = 61/267 (22.85%), Postives = 112/267 (41.95%), Query Frame = 1 
Query: 1267 SIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-----KSYVQPITTKKE------NKEIVP-------KIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            SI +SW+ P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G      +  +P T   E      N    P         PV ++   +     +I+W ++ +   ++  ++ +    +      N  +   N ++    +  + P T YE  V   +    + S +SM    TT E  P+ PP+ +T+ + + K              I V+WQPP + NG+I  Y+I+ + D   ++ +W
Sbjct:  753 SIVVSWTPPENQNIV-VRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSV--MVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPK-----------TIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDW 1005

HSP 2 Score: 32.7278 bits (73), Expect = 3.780e-10
Identity = 15/43 (34.88%), Postives = 21/43 (48.84%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGP 2168
            I  L L+  YYF+I   N  G  P+S    F+TP  +  +  P
Sbjct: 1019 IQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSDKMP 1061
[Close]
BLAST of Netrin receptor DCC vs. TrEMBL
Match: A0A504YMV1 (Netrin receptor DCC (Fragment) OS=Fasciola gigantica OX=46835 GN=FGIG_08374 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 9.559e-38
Identity = 84/307 (27.36%), Postives = 136/307 (44.30%), Query Frame = 1 
Query: 1312 YTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSY------VQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSS-------------TVIN---------------IKNMNPATTYEIMVRNCLVNSSKCSD--------------------YSMVLEFTTQETKPSDPPQHL------------TLSTVQIKNVPSD----NTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            Y I WG+++PGP++  + G +T+++IE+L P T Y++++   T  G G +       + P+T +       P IPVNL +  VG TWA++ W    + + E   + +FQ++YY+I     ++                     TV N               ++ + P T YE  V  CL+ S   +D                    +SMV  F T    P DPPQ +            T+  VQ+   PSD    ++     + I+V W  P + NG I  Y+I++TA++K  V +W ER+V G
Sbjct:  476 YLIRWGDMHPGPAEDSVRGDQTEYLIENLRPGTIYYIRVIAVTQLGEGPAAYTVTRTLNPVTDELTPATSGPLIPVNLVVQAVGSTWARVGWELSNLPSAETMPSLMFQIKYYAITADGFHDTQHGYRRGLSTYERDVELVNLTVPNRNRGAKRVGSHYKAMLRGLRPGTQYEFGV--CLIQSHLTNDLNAVEVRDNRASAMATSPYCWSMVQGFETFGQHPKDPPQRIRVLIPLSDTKPETIGLVQLD--PSDSGGLSSDGGKTYPIRVIWDSPSQSNGPILAYVIYLTANRKQSVTHWFERSVDG 778

HSP 2 Score: 73.1738 bits (178), Expect = 9.559e-38
Identity = 33/60 (55.00%), Postives = 41/60 (68.33%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEEL 2219
            I  LDLNR YY +I   N +G+SPLSS+ +F+TPD  G  GG   LS+EYYDA +I E L
Sbjct:  785 IRGLDLNRVYYMQIAARNRHGRSPLSSVIVFRTPDAQGIGGGMFKLSREYYDARDINEPL 844
[Close]
BLAST of Netrin receptor DCC vs. TrEMBL
Match: A0A4E0RKI9 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_000263 PE=4 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 9.242e-37
Identity = 82/307 (26.71%), Postives = 135/307 (43.97%), Query Frame = 1 
Query: 1312 YTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYV------QPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSS-------------TVIN---------------IKNMNPATTYEIMVRNCLVNSSKCSD--------------------YSMVLEFTTQETKPSDPPQHL------------TLSTVQIKNVPSD----NTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            Y I WG+++PGP++  + G +T+++IE+L P T Y++++   T  G G +         P+T +       P IPVNL +  VG TWA++ W    + + +   + +FQ++YY+I     ++                     TV N               ++ + P T YE  V  CL+ S   +D                    +SMV  F T    P DPPQ +            T+  VQ+   PSD    ++     + I+V W  P + NG I  Y+I++TA++K  + +W ER+V G
Sbjct:  630 YLIRWGDMHPGPAEDSVRGDQTEYLIENLRPGTIYYIRVIAVTQLGEGPAAYTVTRTHNPVTDELTPATSGPLIPVNLVVQAVGSTWARVGWELSSLPSADTMPSLMFQIKYYAITADGFHDTQHGYRRGLSTYERDVELVNLTVPNRNRGAKRVGSHYKAMLRGLRPGTQYEFGV--CLIQSHLTNDPNAVGIRDNRASAVATSPYCWSMVQGFETFGQHPKDPPQRIRVLIPLSDTKPETIGLVQLD--PSDSGGLSSDGGKTYPIRVIWDSPSQSNGPILAYVIYLTANRKQSLTHWFERSVDG 932

HSP 2 Score: 73.559 bits (179), Expect = 9.242e-37
Identity = 37/80 (46.25%), Postives = 48/80 (60.00%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDA-----------TEITEELKIQTSNERG 2246
            I  LDLNR YY +I   N +G+SPLSS+ +F+TPD  G  GG   LS+EYYDA           T I+E L  QT++ +G
Sbjct:  939 IRGLDLNRVYYMQIAARNRHGRSPLSSVIVFRTPDAQGIGGGMFKLSREYYDARDINEPLVTMVTGISEALGTQTADLKG 1018
[Close]
BLAST of Netrin receptor DCC vs. TrEMBL
Match: A0A4S2LH98 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007226 PE=4 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 1.117e-33
Identity = 83/310 (26.77%), Postives = 137/310 (44.19%), Query Frame = 1 
Query: 1294 IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEI------VPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXS----STVINI-----------------------KNMNPATTYEIMVRNCLVNSSK------------------CSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSD--NTLTKNRFA--------------IQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            + P   Y + WG+++PGPS+  + G +T++++E+L P T Y+V++   T  G G +      T+    +        P IPVNL +  VG TWA++ W    +    +S+  +F+++YY I    +  H     S    +TVI +                       + + PAT YE  V  CL+++                    C  +SMV  F T    PSD P ++ +S      VP D  + LT+N  A              +++ W  P + NGEI  Y+I+++AD+   V++W E  V G
Sbjct:  674 LPPGTKYIVRWGDMHPGPSEDTVMGDQTEYLMENLRPGTIYYVRVIAVTRLGDGPAAYTVTMTRSLTSDTGNPSSNGPIIPVNLVVRAVGSTWARVGWELPELPTRLQSQVLLFKIKYYPINVDRSTIHPFQTGSPSSEATVITVNLSVPLSPTTPASQQSWPFKAVLRGLQPATQYEFGV--CLLDTPTNEASFHMPMKGQTMSPELC--WSMVQGFETFGKNPSDAPTNIRIS------VPRDLADPLTQNEGAGREDKRSSAKPGVLVRLHWDAPLRTNGEIGAYVIYLSADRSKSVNDWSEHIVPG 973

HSP 2 Score: 66.6254 bits (161), Expect = 1.117e-33
Identity = 64/233 (27.47%), Postives = 103/233 (44.21%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKI---------QTSNERGNDNLVDXXXXXXXXXXXXXXXXXXXXYKWWIIIGXXXXXXXXXXXXXXXXXXXKCRNENIPYENGIKIMKGKNACDVDYMNSGKENI-KFINKVPILTTPDLFRHTNDQNCHQNYLEMEERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTP 2717
            L   + Y+ R+   N +G SP S +  F+TPD NG+ GG + LSK YYDA EI E L           Q +  R ++N VD ++  ++ +              WII+G V G  +V +L+   ++  +CRN      N + IMK ++     YM SG  N+ +     P   +      +   +CH     +       ++   +    + S N     +P+ H  SGH+TP
Sbjct:  983 LQPKQIYFLRMVARNRHGTSPFSPVVAFRTPDSNGQGGGMVRLSKTYYDAREIFEPLDTVIPAGVDQNQAAGVRSSNNAVDETSGADQLR--------------WIIVGSVLGGTVVIVLVATAVLFTRCRNS----RNSLGIMK-RSTSKQPYM-SGYPNVYRSDTTGPADLSTKTASFSLQDHCHGG-CSVAGSGAGGSNSGCHLVGCTLSDNPPMDPRPSSHECSGHHTP 1194
[Close]
BLAST of Netrin receptor DCC vs. TrEMBL
Match: A0A4S2LNQ8 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007226 PE=4 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 1.275e-33
Identity = 83/310 (26.77%), Postives = 137/310 (44.19%), Query Frame = 1 
Query: 1294 IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEI------VPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXS----STVINI-----------------------KNMNPATTYEIMVRNCLVNSSK------------------CSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSD--NTLTKNRFA--------------IQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            + P   Y + WG+++PGPS+  + G +T++++E+L P T Y+V++   T  G G +      T+    +        P IPVNL +  VG TWA++ W    +    +S+  +F+++YY I    +  H     S    +TVI +                       + + PAT YE  V  CL+++                    C  +SMV  F T    PSD P ++ +S      VP D  + LT+N  A              +++ W  P + NGEI  Y+I+++AD+   V++W E  V G
Sbjct:  674 LPPGTKYIVRWGDMHPGPSEDTVMGDQTEYLMENLRPGTIYYVRVIAVTRLGDGPAAYTVTMTRSLTSDTGNPSSNGPIIPVNLVVRAVGSTWARVGWELPELPTRLQSQVLLFKIKYYPINVDRSTIHPFQTGSPSSEATVITVNLSVPLSPTTPASQQSWPFKAVLRGLQPATQYEFGV--CLLDTPTNEASFHMPMKGQTMSPELC--WSMVQGFETFGKNPSDAPTNIRIS------VPRDLADPLTQNEGAGREDKRSSAKPGVLVRLHWDAPLRTNGEIGAYVIYLSADRSKSVNDWSEHIVPG 973

HSP 2 Score: 66.6254 bits (161), Expect = 1.275e-33
Identity = 64/233 (27.47%), Postives = 103/233 (44.21%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKI---------QTSNERGNDNLVDXXXXXXXXXXXXXXXXXXXXYKWWIIIGXXXXXXXXXXXXXXXXXXXKCRNENIPYENGIKIMKGKNACDVDYMNSGKENI-KFINKVPILTTPDLFRHTNDQNCHQNYLEMEERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTP 2717
            L   + Y+ R+   N +G SP S +  F+TPD NG+ GG + LSK YYDA EI E L           Q +  R ++N VD ++  ++ +              WII+G V G  +V +L+   ++  +CRN      N + IMK ++     YM SG  N+ +     P   +      +   +CH     +       ++   +    + S N     +P+ H  SGH+TP
Sbjct:  983 LQPKQIYFLRMVARNRHGTSPFSPVVAFRTPDSNGQGGGMVRLSKTYYDAREIFEPLDTVIPAGVDQNQAAGVRSSNNAVDETSGADQLR--------------WIIVGSVLGGTVVIVLVATAVLFTRCRNS----RNSLGIMK-RSTSKQPYM-SGYPNVYRSDTTGPADLSTKTASFSLQDHCHGG-CSVAGSGAGGSNSGCHLVGCTLSDNPPMDPRPSSHECSGHHTP 1194
[Close]
BLAST of Netrin receptor DCC vs. TrEMBL
Match: A0A3R7C7J3 (Neogenin-like protein (Fragment) OS=Clonorchis sinensis OX=79923 GN=CSKR_11433s PE=4 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 8.261e-32
Identity = 79/306 (25.82%), Postives = 135/306 (44.12%), Query Frame = 1 
Query: 1294 IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEI------VPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXX----XXXXXXXSSTVINI-----------------------KNMNPATTYEIMVRNCLVN-SSKCSDY---------------SMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFA--------------IQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            + P   Y I WG+++PGPS+  + G +T+++IE L P T Y++++   T  G G +      T+    +        P IPVNL +  VG TWA++ W    +    +S+  +F+++YY I    +          +  +T+I +                       + + PAT YE  V  CL++  ++ S++               SMV  F T    PSD P ++ +S  +    P    LT+N  A              +++ W  P + NGEI  Y+I+++AD+   V++W E  V G
Sbjct:  511 LPPGTKYIIRWGDMHPGPSEDTVMGDQTEYLIEKLRPGTIYYIRVIAVTRLGDGPAAYTVTMTRSLTSDTGNPSSNGPIIPVNLVVRAVGSTWARVGWELPELPTRLQSQVLLFKIKYYPINVDRSTMHPFQTGIPSSQATMITVNLSVPLNPTTTASQQSWPFKAVLRGLQPATQYEFGV--CLLDPPTEGSNFHMPMMSQTISPELCWSMVQGFETFGKNPSDAPTNIRISVPRGLADP----LTQNEGAGSEGKPSSAKTGVFVRLHWDAPLRANGEIGAYVIYLSADRSKSVNDWSEHIVPG 810

HSP 2 Score: 63.929 bits (154), Expect = 8.261e-32
Identity = 51/162 (31.48%), Postives = 78/162 (48.15%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKI---------QTSNERGNDNLVDXXXXXXXXXXXXXXXXXXXXYKWWIIIGXXXXXXXXXXXXXXXXXXXKCRNENIPYENGIKIMKGKNACDVDYMNSGKENI 2507
            L   + Y+ R+   N +G SP S +  F+TPD NG+ GG + LSK YYDA EI E L           Q +  R ++N VD  +  ++ +              WII+G V G  +V +L+   ++ ++CR       N + IMK ++     YM SG  N+
Sbjct:  820 LQPKQIYFLRMVARNRHGTSPFSPVVAFRTPDSNGQGGGMVRLSKTYYDAREIFEPLDTVIPAGVDQNQAAGVRPSNNAVDEPSGADQLR--------------WIIVGSVLGGTVVIVLVATAVLFSRCRKS----RNSLGIMK-RSTSKQPYM-SGYPNV 961
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Cavefish
Match: dcc (DCC netrin 1 receptor [Source:NCBI gene;Acc:569360])

HSP 1 Score: 80.4925 bits (197), Expect = 5.985e-17
Identity = 70/285 (24.56%), Postives = 124/285 (43.51%), Query Frame = 1 
Query: 1264 NSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKK-------------------------ENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVI----NIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            NSI +SW+ P+ P   V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G    +   T+                           +  ++P  PV ++ V +     ++SW ++ I   ++S     +V YYS++ + +++ +    S+        +  + P T YE  V   +    K S +SM    TT E  PS  P+ LT+  +  +  P          +I +SWQPP + NG I  Y+++ T DK + +D+W    +SG
Sbjct:  722 NSIIMSWTPPLNPNILVRGYIIGYGVGSPYAETVRVDSKQRYYSIENLEPSSHYVISLKAFNNAGEGVPLYESAVTRSMSDPVDPSDDDLFHLFDKFPTPIPDTSTPMIP--PVGVQAVALTSDSVRVSWADNSISKNQKSS----EVRYYSVKWKTSHSTSGKYKSADTTALSHTVTGLKPNTMYEFAV--MVTKGRKSSTWSMTAHATTYEAAPSSAPKDLTV--IGREGRPR---------SILISWQPPLEANGRITGYIVYYTLDKNMPIDDWVMEPISG 987

HSP 2 Score: 27.7202 bits (60), Expect = 5.985e-17
Identity = 16/44 (36.36%), Postives = 22/44 (50.00%), Query Frame = 3 
Query: 2049 LDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            L+L+  YYFRI   N  G  PLS    ++T     PD+   + G
Sbjct:  997 LNLDTVYYFRIQAKNAKGVGPLSDPVQYRTSKVEHPDKMANDQG 1040
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Cavefish
Match: neo1a (neogenin-like [Source:NCBI gene;Acc:103031419])

HSP 1 Score: 70.4774 bits (171), Expect = 3.267e-15
Identity = 70/256 (27.34%), Postives = 118/256 (46.09%), Query Frame = 1 
Query: 1264 NSIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-KSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNM----NPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            NSI +SWS P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G   Y   IT  +   + +P +P V ++   +     K++W ++ +   ++    I    YY++R + N   N    ++    + +M     P T YE  V   +    K S +SM    TT E  PS  P+ +T+ + +          T+ R  I V+WQPP + NG+I  Y+I+ + D   +V +W
Sbjct:  731 NSIVVSWSPPENQDIV-VRGYIIGYGIGSPHAQTIKVDYKQRYYSIENLDPSSHYVITLKAFNNVGEGIPVYESAITRPQSVPDPIPMMPPVGVQASVLSHDTIKVTWADNSLPKNQK----ITDARYYTVRWKTNIPANTKYKTANTTTLSHMVTGLKPNTLYEFSV--MVTKGRKTSTWSMTAHGTTFEATPSSAPKDVTVVSKE----------TRPRTII-VNWQPPSEANGKITGYIIYYSTDVNAEVHDW 968

HSP 2 Score: 31.9574 bits (71), Expect = 3.267e-15
Identity = 16/43 (37.21%), Postives = 21/43 (48.84%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGP 2168
            I  L L+  YYF+I   N  G  P+S    F+TP  +   G P
Sbjct:  982 IQDLTLDTTYYFKIQARNSKGMGPMSEAVHFRTPKASSIPGKP 1024
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Cavefish
Match: neo1a (neogenin-like [Source:NCBI gene;Acc:103031419])

HSP 1 Score: 70.8626 bits (172), Expect = 1.169e-14
Identity = 70/256 (27.34%), Postives = 118/256 (46.09%), Query Frame = 1 
Query: 1264 NSIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-KSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNM----NPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            NSI +SWS P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G   Y   IT  +   + +P +P V ++   +     K++W ++ +   ++    I    YY++R + N   N    ++    + +M     P T YE  V   +    K S +SM    TT E  PS  P+ +T+ + +          T+ R  I V+WQPP + NG+I  Y+I+ + D   +V +W
Sbjct:  731 NSIVVSWSPPENQDIV-VRGYIIGYGIGSPHAQTIKVDYKQRYYSIENLDPSSHYVITLKAFNNVGEGIPVYESAITRPQSVPDPIPMMPPVGVQASVLSHDTIKVTWADNSLPKNQK----ITDARYYTVRWKTNIPANTKYKTANTTTLSHMVTGLKPNTLYEFSV--MVTKGRKTSTWSMTAHGTTFEATPSSAPKDVTVVSKE----------TRPRTII-VNWQPPSEANGKITGYIIYYSTDVNAEVHDW 968

HSP 2 Score: 30.0314 bits (66), Expect = 1.169e-14
Identity = 14/34 (41.18%), Postives = 18/34 (52.94%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            I  L L+  YYF+I   N  G  P+S    F+TP
Sbjct:  982 IQDLTLDTTYYFKIQARNSKGMGPMSEAVHFRTP 1015
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Cavefish
Match: neo1a (neogenin-like [Source:NCBI gene;Acc:103031419])

HSP 1 Score: 70.8626 bits (172), Expect = 1.198e-14
Identity = 70/256 (27.34%), Postives = 118/256 (46.09%), Query Frame = 1 
Query: 1264 NSIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-KSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNM----NPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            NSI +SWS P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G   Y   IT  +   + +P +P V ++   +     K++W ++ +   ++    I    YY++R + N   N    ++    + +M     P T YE  V   +    K S +SM    TT E  PS  P+ +T+ + +          T+ R  I V+WQPP + NG+I  Y+I+ + D   +V +W
Sbjct:  717 NSIVVSWSPPENQDIV-VRGYIIGYGIGSPHAQTIKVDYKQRYYSIENLDPSSHYVITLKAFNNVGEGIPVYESAITRPQSVPDPIPMMPPVGVQASVLSHDTIKVTWADNSLPKNQK----ITDARYYTVRWKTNIPANTKYKTANTTTLSHMVTGLKPNTLYEFSV--MVTKGRKTSTWSMTAHGTTFEATPSSAPKDVTVVSKE----------TRPRTII-VNWQPPSEANGKITGYIIYYSTDVNAEVHDW 954

HSP 2 Score: 29.6462 bits (65), Expect = 1.198e-14
Identity = 14/34 (41.18%), Postives = 18/34 (52.94%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            I  L L+  YYF+I   N  G  P+S    F+TP
Sbjct:  968 IQDLTLDTTYYFKIQARNSKGMGPMSEAVHFRTP 1001
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Cavefish
Match: neo1a (neogenin-like [Source:NCBI gene;Acc:103031419])

HSP 1 Score: 70.4774 bits (171), Expect = 1.278e-14
Identity = 70/256 (27.34%), Postives = 118/256 (46.09%), Query Frame = 1 
Query: 1264 NSIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG-KSYVQPITTKKENKEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNM----NPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            NSI +SWS P    IV V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G   Y   IT  +   + +P +P V ++   +     K++W ++ +   ++    I    YY++R + N   N    ++    + +M     P T YE  V   +    K S +SM    TT E  PS  P+ +T+ + +          T+ R  I V+WQPP + NG+I  Y+I+ + D   +V +W
Sbjct:  731 NSIVVSWSPPENQDIV-VRGYIIGYGIGSPHAQTIKVDYKQRYYSIENLDPSSHYVITLKAFNNVGEGIPVYESAITRPQSVPDPIPMMPPVGVQASVLSHDTIKVTWADNSLPKNQK----ITDARYYTVRWKTNIPANTKYKTANTTTLSHMVTGLKPNTLYEFSV--MVTKGRKTSTWSMTAHGTTFEATPSSAPKDVTVVSKE----------TRPRTII-VNWQPPSEANGKITGYIIYYSTDVNAEVHDW 968

HSP 2 Score: 30.0314 bits (66), Expect = 1.278e-14
Identity = 14/34 (41.18%), Postives = 18/34 (52.94%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            I  L L+  YYF+I   N  G  P+S    F+TP
Sbjct:  982 IQDLTLDTTYYFKIQARNSKGMGPMSEAVHFRTP 1015
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Nematostella
Match: EDO46961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNP0])

HSP 1 Score: 46.9802 bits (110), Expect = 1.234e-6
Identity = 30/102 (29.41%), Postives = 47/102 (46.08%), Query Frame = 1 
Query: 1696 IKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            +  + P ++YE   R   VNS   S  S++ E+TT ETKP   P+++    V      SD +        +  W PP   NG I+ Y ++ + D   D+  W
Sbjct:  343 VSGLRPFSSYEF--RVFAVNSLGRSRPSLMAEYTTSETKPGSAPRNIEAMGV------SDTSF-------KAGWLPPISANGRIRGYRLYYSLDLLEDISQW 429

HSP 2 Score: 24.6386 bits (52), Expect = 1.234e-6
Identity = 19/69 (27.54%), Postives = 30/69 (43.48%), Query Frame = 3 
Query: 2016 QWKGL-----NTVIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEI 2207
            QW+ +     +T +  L     ++FRI   N  G  PLS +   KT  + G  G P ++      +T I
Sbjct:  428 QWRFMASSTNSTTVTGLTRQTTHFFRILAYNIAGDGPLSEVVAVKT--QKGVPGQPRSVQLSVLSSTAI 494
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Medaka
Match: dcc (DCC netrin 1 receptor [Source:NCBI gene;Acc:101164079])

HSP 1 Score: 83.5741 bits (205), Expect = 4.166e-18
Identity = 71/283 (25.09%), Postives = 126/283 (44.52%), Query Frame = 1 
Query: 1264 NSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG---------KSYVQPITTKKEN-------------KEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVI----NIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            NSI +SW+ P+ P   V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G         +S   PI   +++                 P IP V ++ V +     ++SW ++ +   ++S     +V YYS++ +++ + +    S+        I  + P T YE  V   +    K S +SM    TT E  PS  P+ LT+ + + +             ++ +SWQPP + NG I  Y+++ T DK + +D+W    +SG
Sbjct:  730 NSIIMSWTPPLSPNILVRGYIIGYGVGSPYAETVRVDSKQRYYSIENLEPSSHYVISLKAFNNAGEGVPLYESAVTRSLTDPIDPLEDDLFHLFDKYPTPMPDTSTPMIPPVGVQAVALSSDSVRMSWADNSMTKNQKSS----EVRYYSVKWKSSYSTSGKYKSADTTALSHTITGLKPNTMYEFAV--MVTKGRKSSTWSMTAHATTYEAAPSSAPKDLTVISREGRP-----------RSVLISWQPPLEANGRITGYILYYTMDKNIPIDDWVMEAISG 995

HSP 2 Score: 28.8758 bits (63), Expect = 4.166e-18
Identity = 19/48 (39.58%), Postives = 25/48 (52.08%), Query Frame = 3 
Query: 2037 VIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            V+D L+L+  YYFRI   N  G  PLS    F+T     PD+   + G
Sbjct: 1002 VVD-LNLDTVYYFRIQAKNAKGVGPLSEPIHFRTAKVEHPDKMANDQG 1048
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Medaka
Match: dcc (DCC netrin 1 receptor [Source:NCBI gene;Acc:101164079])

HSP 1 Score: 82.8037 bits (203), Expect = 6.115e-18
Identity = 71/283 (25.09%), Postives = 126/283 (44.52%), Query Frame = 1 
Query: 1264 NSIKISWSQPIVP---VKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG---------KSYVQPITTKKEN-------------KEIVPKIP-VNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVI----NIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            NSI +SW+ P+ P   V+ Y I +G   P      +  K+  + IE+L PS++Y + +      G G         +S   PI   +++                 P IP V ++ V +     ++SW ++ +   ++S     +V YYS++ +++ + +    S+        I  + P T YE  V   +    K S +SM    TT E  PS  P+ LT+ + + +             ++ +SWQPP + NG I  Y+++ T DK + +D+W    +SG
Sbjct:  764 NSIIMSWTPPLSPNILVRGYIIGYGVGSPYAETVRVDSKQRYYSIENLEPSSHYVISLKAFNNAGEGVPLYESAVTRSLTDPIDPLEDDLFHLFDKYPTPMPDTSTPMIPPVGVQAVALSSDSVRMSWADNSMTKNQKSS----EVRYYSVKWKSSYSTSGKYKSADTTALSHTITGLKPNTMYEFAV--MVTKGRKSSTWSMTAHATTYEAAPSSAPKDLTVISREGRP-----------RSVLISWQPPLEANGRITGYILYYTMDKNIPIDDWVMEAISG 1029

HSP 2 Score: 28.8758 bits (63), Expect = 6.115e-18
Identity = 19/48 (39.58%), Postives = 25/48 (52.08%), Query Frame = 3 
Query: 2037 VIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKT-----PDENGKNGG 2165
            V+D L+L+  YYFRI   N  G  PLS    F+T     PD+   + G
Sbjct: 1036 VVD-LNLDTVYYFRIQAKNAKGVGPLSEPIHFRTAKVEHPDKMANDQG 1082
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Medaka
Match: neo1b (neogenin 1 [Source:NCBI gene;Acc:101164964])

HSP 1 Score: 70.0922 bits (170), Expect = 1.273e-15
Identity = 73/279 (26.16%), Postives = 123/279 (44.09%), Query Frame = 1 
Query: 1264 NSIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIG---------------------KSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSG 2022
            NSI +SW+ P    IV V+ YTI++G   P      +  K+  + IE+L PS+ Y + +      G G                     + +  P T   ++  ++P  PV ++   +     K++W ++ + KN + + N  + V + +    N         S + I +  + P T YE  V   L    + S +SM  + TT E+ PS PP+ +T+  V  +N P           I V+WQPP + NG+I  Y+I+ + D   +V +W    V G
Sbjct:  688 NSIVVSWTPPENQDIV-VRGYTIDYGIGSPHSQTIKVDYKQRYYTIENLNPSSQYVITLKAFNNVGEGIPLYESTATRWDTQYPDVDLYELFPAPYTPVPDHTPMMP--PVGVQASVLTHDTIKVTWADNTLPKNQKITDNRFYTVRWKTNIPANTKVKMANTSSLSHI-VTGLKPNTLYEFSV--MLTKGRRASTWSMTAQGTTFESIPSSPPKDVTV--VSKENKPR---------TIIVNWQPPSEANGKITGYIIYYSTDVNAEVHDWVIEPVVG 949

HSP 2 Score: 33.8834 bits (76), Expect = 1.273e-15
Identity = 15/37 (40.54%), Postives = 20/37 (54.05%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDEN 2150
            I  L L+  YYF+I   N  G  P+S   +F+TP  N
Sbjct:  956 IQELTLDTTYYFKIQARNSKGMGPMSDAVLFRTPKSN 992
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Medaka
Match: neo1b (neogenin 1 [Source:NCBI gene;Acc:101164964])

HSP 1 Score: 70.8626 bits (172), Expect = 2.997e-15
Identity = 71/269 (26.39%), Postives = 120/269 (44.61%), Query Frame = 1 
Query: 1264 NSIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENK------EIVPKI------------PVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            NSI +SW+ P    IV V+ YTI++G   P      +  K+  + IE+L PS+ Y + +      G G    +   T+ ++       E+ P              PV ++   +     K++W ++ + KN + + N  + V + +    N         S + I +  + P T YE  V   L    + S +SM  + TT E+ PS PP+ +T+  V  +N P           I V+WQPP + NG+I  Y+I+ + D   +V +W
Sbjct:  765 NSIVVSWTPPENQDIV-VRGYTIDYGIGSPHSQTIKVDYKQRYYTIENLNPSSQYVITLKAFNNVGEGIPLYESTATRAQSDPDVDLYELFPAPYTPVPDHTPMMPPVGVQASVLTHDTIKVTWADNTLPKNQKITDNRFYTVRWKTNIPANTKVKMANTSSLSHI-VTGLKPNTLYEFSV--MLTKGRRASTWSMTAQGTTFESIPSSPPKDVTV--VSKENKPR---------TIIVNWQPPSEANGKITGYIIYYSTDVNAEVHDW 1018

HSP 2 Score: 31.9574 bits (71), Expect = 2.997e-15
Identity = 14/34 (41.18%), Postives = 19/34 (55.88%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            I  L L+  YYF+I   N  G  P+S   +F+TP
Sbjct: 1032 IQELTLDTTYYFKIQARNSKGMGPMSDAVLFRTP 1065
[Close]
BLAST of Netrin receptor DCC vs. Ensembl Medaka
Match: neo1b (neogenin 1 [Source:NCBI gene;Acc:101164964])

HSP 1 Score: 70.8626 bits (172), Expect = 3.307e-15
Identity = 71/269 (26.39%), Postives = 120/269 (44.61%), Query Frame = 1 
Query: 1264 NSIKISWSQP----IVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENK------EIVPKI------------PVNLKLVEVGDTWAKISWNEDYI-KNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNW 2001
            NSI +SW+ P    IV V+ YTI++G   P      +  K+  + IE+L PS+ Y + +      G G    +   T+ ++       E+ P              PV ++   +     K++W ++ + KN + + N  + V + +    N         S + I +  + P T YE  V   L    + S +SM  + TT E+ PS PP+ +T+  V  +N P           I V+WQPP + NG+I  Y+I+ + D   +V +W
Sbjct:  765 NSIVVSWTPPENQDIV-VRGYTIDYGIGSPHSQTIKVDYKQRYYTIENLNPSSQYVITLKAFNNVGEGIPLYESTATRAQSDPDVDLYELFPAPYTPVPDHTPMMPPVGVQASVLTHDTIKVTWADNTLPKNQKITDNRFYTVRWKTNIPANTKVKMANTSSLSHI-VTGLKPNTLYEFSV--MLTKGRRASTWSMTAQGTTFESIPSSPPKDVTV--VSKENKPR---------TIIVNWQPPSEANGKITGYIIYYSTDVNAEVHDW 1018

HSP 2 Score: 31.9574 bits (71), Expect = 3.307e-15
Identity = 14/34 (41.18%), Postives = 19/34 (55.88%), Query Frame = 3 
Query: 2040 IDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTP 2141
            I  L L+  YYF+I   N  G  P+S   +F+TP
Sbjct: 1032 IQELTLDTTYYFKIQARNSKGMGPMSDAVLFRTP 1065
[Close]
BLAST of Netrin receptor DCC vs. Planmine SMEST
Match: SMESG000056891.1 (SMESG000056891.1)

HSP 1 Score: 1311.59 bits (3393), Expect = 0.000e+0
Identity = 670/672 (99.70%), Postives = 671/672 (99.85%), Query Frame = 1 
Query:   13 MKNIFWIINFLAILDHYLFYCIEYNPFTILVNRNSHLSISCFLSDNDTNTKWLTFNTNFEITDLHNDSHHTISPNGTLKIFNFKNTKLYYQCVSVSKTQILFEKIFQIVSIEHXXXXXXXXXEQIFKLSKPILFTSKLVVGKNTKLIWVMWKNNRFYDISLSNKIVQFDSSIKVMILSLNNVLSFVACLKQTITNLIITCDKPHFIRSSKLDEHSKVMYSEVNDYVILQCRNSSDNHKYRWFKNGKLIEFGERITNYGNIISIRNITVDDYGYYQCYISKPFTLPYKLSIFLINFYNSSDLFHSFVKMNDKKSPLILPCKHHSPGTPSFIYWNLDKISSFSQLLNVTNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWSQPIVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGKA 2028
            MKNIFWIINFLAILDHYLFYCIEYNPF ILVNRNSHLSISCFLSDNDTNTKWLTFNTNFEITDLHNDSHHTISPNGTLKIFNFKNTKLYYQCVSVSKTQILFEKIFQIVSIEHLFNNNLLNFEQIFKLSKPILFTSKLVVGKNTKLIWVMWKNNRFYDISLSNKIVQFDSSIKVMILSLNNVLSFVACLKQTITNLIITCDKPHFIRSSKLDEHSKVMYSEVNDYVILQCRNSSDNHKYRWFKNGKLIEFGERITNYGNIISIRNITVDDYGYYQCYISKPFTLPYKLSIFLINFYNSSDLFHSFVKMNDKKSPLILPCKHHSPGTPSFIYWNLDKISSFSQLLNVTNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWSQPIVPVKTYTINWGNLYPGPSK+IISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIRNQNNNNHNRLNLSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGKA
Sbjct:    1 MKNIFWIINFLAILDHYLFYCIEYNPFIILVNRNSHLSISCFLSDNDTNTKWLTFNTNFEITDLHNDSHHTISPNGTLKIFNFKNTKLYYQCVSVSKTQILFEKIFQIVSIEHLFNNNLLNFEQIFKLSKPILFTSKLVVGKNTKLIWVMWKNNRFYDISLSNKIVQFDSSIKVMILSLNNVLSFVACLKQTITNLIITCDKPHFIRSSKLDEHSKVMYSEVNDYVILQCRNSSDNHKYRWFKNGKLIEFGERITNYGNIISIRNITVDDYGYYQCYISKPFTLPYKLSIFLINFYNSSDLFHSFVKMNDKKSPLILPCKHHSPGTPSFIYWNLDKISSFSQLLNVTNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWSQPIVPVKTYTINWGNLYPGPSKRIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIRNQNNNNHNRLNLSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGKA 672

HSP 2 Score: 690.649 bits (1781), Expect = 0.000e+0
Identity = 404/412 (98.06%), Postives = 406/412 (98.54%), Query Frame = 3 
Query: 2001 GRKNCQWKGLNTVIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKIQTSNERGNDNLVDXXXXXXXXXXXXXXXXXXXXYKWWIIIGXXXXXXXXXXXXXXXXXXXKCRNENIPYENGIKIMKGKNACDVDYMNSGKENIKFINKVPILTTPDLFRHTNDQNCHQNYLEMEERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTPPGLIHQQNMVMTTSQLTSNSNERQFYQVPFMHHMGHNQMNVFTSSAPRVNAAASDFNSINIPSPISGYSDFTSSQATVLYDXXXXXXXXXXXXXXXXXXXXXXXXXKAPLVNEPINEGMNNCEKSTEIENNKSSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC 3236
            G +    K LNTVIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKIQTSNERGNDNLVDTSTNNNETKNKTLTKLSLTNYKWWIIIGIVFGAILVFILIILFLVAAKCRNENIPYENGIKIMKGKNACDVDYMNSGKENIKFINKVPILTTPDLFRHTNDQNCHQNYLEMEERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTPPGLIHQQNMVMTTSQLTSNSNERQFYQVPFMHHMGHNQMNVFTSSAPRVNAAASDFNSINIPSPISGYSDFTSSQATVLYDTSTAKSSGGKSSLSGSGSYNNGLASKAPLVNEPINEGMNNCEKSTE+ENNKSSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC
Sbjct:  664 GERTVSGKALNTVIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKIQTSNERGNDNLVDTSTNNNETKNKTLTKLSLTNYKWWIIIGIVFGAILVFILIILFLVAAKCRNENIPYENGIKIMKGKNACDVDYMNSGKENIKFINKVPILTTPDLFRHTNDQNCHQNYLEMEERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTPPGLIHQQNMVMTTSQLTSNSNERQFYQVPFMHHMGHNQMNVFTSSAPRVNAAASDFNSINIPSPISGYSDFTSSQATVLYDTSTAKSSGGKSSLSGSGSYNNGLASKAPLVNEPINEGMNNCEKSTEVENNKSSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC 1075
[Close]
BLAST of Netrin receptor DCC vs. Planmine SMEST
Match: SMESG000056891.1 (SMESG000056891.1)

HSP 1 Score: 1310.05 bits (3389), Expect = 0.000e+0
Identity = 670/672 (99.70%), Postives = 671/672 (99.85%), Query Frame = 1 
Query:   13 MKNIFWIINFLAILDHYLFYCIEYNPFTILVNRNSHLSISCFLSDNDTNTKWLTFNTNFEITDLHNDSHHTISPNGTLKIFNFKNTKLYYQCVSVSKTQILFEKIFQIVSIEHXXXXXXXXXEQIFKLSKPILFTSKLVVGKNTKLIWVMWKNNRFYDISLSNKIVQFDSSIKVMILSLNNVLSFVACLKQTITNLIITCDKPHFIRSSKLDEHSKVMYSEVNDYVILQCRNSSDNHKYRWFKNGKLIEFGERITNYGNIISIRNITVDDYGYYQCYISKPFTLPYKLSIFLINFYNSSDLFHSFVKMNDKKSPLILPCKHHSPGTPSFIYWNLDKISSFSQLLNVTNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWSQPIVPVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGKA 2028
            MKNIFWIINFLAILDHYLFYCIEYNPF ILVNRNSHLSISCFLSDNDTNTKWLTFNTNFEITDLHNDSHHTISPNGTLKIFNFKNTKLYYQCVSVSKTQILFEKIFQIVSIEHLFNNNLLNFEQIFKLSKPILFTSKLVVGKNTKLIWVMWKNNRFYDISLSNKIVQFDSSIKVMILSLNNVLSFVACLKQTITNLIITCDKPHFIRSSKLDEHSKVMYSEVNDYVILQCRNSSDNHKYRWFKNGKLIEFGERITNYGNIISIRNITVDDYGYYQCYISKPFTLPYKLSIFLINFYNSSDLFHSFVKMNDKKSPLILPCKHHSPGTPSFIYWNLDKISSFSQLLNVTNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWSQPIVPVKTYTINWGNLYPGPSK+IISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIRNQNNNNHNRLNLSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGKA
Sbjct:    1 MKNIFWIINFLAILDHYLFYCIEYNPFIILVNRNSHLSISCFLSDNDTNTKWLTFNTNFEITDLHNDSHHTISPNGTLKIFNFKNTKLYYQCVSVSKTQILFEKIFQIVSIEHLFNNNLLNFEQIFKLSKPILFTSKLVVGKNTKLIWVMWKNNRFYDISLSNKIVQFDSSIKVMILSLNNVLSFVACLKQTITNLIITCDKPHFIRSSKLDEHSKVMYSEVNDYVILQCRNSSDNHKYRWFKNGKLIEFGERITNYGNIISIRNITVDDYGYYQCYISKPFTLPYKLSIFLINFYNSSDLFHSFVKMNDKKSPLILPCKHHSPGTPSFIYWNLDKISSFSQLLNVTNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQIILKKRSIPEASITTFEFISTSNSIKISWSQPIVPVKTYTINWGNLYPGPSKRIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIRNQNNNNHNRLNLSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIKNYLIFVTADKKLDVDNWGERTVSGKA 672

HSP 2 Score: 632.869 bits (1631), Expect = 0.000e+0
Identity = 361/412 (87.62%), Postives = 368/412 (89.32%), Query Frame = 3 
Query: 2001 GRKNCQWKGLNTVIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKIQTSNERGNDNLVDXXXXXXXXXXXXXXXXXXXXYKWWIIIGXXXXXXXXXXXXXXXXXXXKCRNENIPYENGIKIMKGKNACDVDYMNSGKENIKFINKVPILTTPDLFRHTNDQNCHQNYLEMEERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTPPGLIHQQNMVMTTSQLTSNSNERQFYQVPFMHHMGHNQMNVFTSSAPRVNAAASDFNSINIPSPISGYSDFTSSQATVLYDXXXXXXXXXXXXXXXXXXXXXXXXXKAPLVNEPINEGMNNCEKSTEIENNKSSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC 3236
            G +    K LNTVIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKIQTSNERGNDNLVDTSTNNNETKNKTLTKLSLTNYKWWIIIGIVFGAILVFILIILFLVAAKCRNENIPYENGIKIMKGKNACDVDYMNSGKENIKFINKVPILTTPDLFRHTNDQNCHQNYLEMEERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTPPGLIHQQNMVMTTSQLTSNSNERQFYQVPFMHHMGHNQMNVFTSSAPRVNAAASDFNSI+  S +SG   + +  A+                             KAPLVNEPINEGMNNCEKSTE+ENNKSSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC
Sbjct:  664 GERTVSGKALNTVIDRLDLNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEITEELKIQTSNERGNDNLVDTSTNNNETKNKTLTKLSLTNYKWWIIIGIVFGAILVFILIILFLVAAKCRNENIPYENGIKIMKGKNACDVDYMNSGKENIKFINKVPILTTPDLFRHTNDQNCHQNYLEMEERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTPPGLIHQQNMVMTTSQLTSNSNERQFYQVPFMHHMGHNQMNVFTSSAPRVNAAASDFNSISGKSSLSGSGSYNNGLAS-----------------------------KAPLVNEPINEGMNNCEKSTEVENNKSSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC 1046
[Close]
BLAST of Netrin receptor DCC vs. Planmine SMEST
Match: SMESG000042475.1 (SMESG000042475.1)

HSP 1 Score: 97.4413 bits (241), Expect = 1.345e-26
Identity = 77/279 (27.60%), Postives = 130/279 (46.59%), Query Frame = 1 
Query: 1213 RSIPEASITTFEFISTSNSIKISWSQPIV--PVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDY----------SMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPN----GEIKNYLIFVTADKKLDVDNW 2001
            +SIP ++IT++     + SI++ WS P    PV TYTI WG +YPGP    +      ++I +L   T Y +KI        G   +   +T   N + +P IP+NL + ++  TW  I+W +    + + S   ++Q+ Y S      +N  +      V  I  +  AT+Y   VR   V   +  +Y          S+   F+T+  +P++ PQ+L L T+   +V + +  TK    + +SW  P         +I  Y I+ T++ K D+ NW
Sbjct:  603 KSIPPSAITSWRAKGLNTSIELQWSHPTGGGPVTTYTIEWGKVYPGPQHVTLKYPINSYLINNLELRTQYMIKIIPINGASPGMELLFSHSTGNPNIKSIP-IPLNLNINQIEKTWVVITWED---PSNDVSNTRLYQIRYSSTDKDFPSNELKNTTEKNV-QITGLRTATSYSFSVRTGDVIPPRDGEYINKEWAWSEWSLKESFSTKGERPTNSPQNLKLVTIGEPDVRNTDVYTK----VALSWSSPITNETVRYDDITRYTIYFTSEPKTDISNW 872

HSP 2 Score: 43.1282 bits (100), Expect = 1.345e-26
Identity = 16/51 (31.37%), Postives = 32/51 (62.75%), Query Frame = 3 
Query: 2055 LNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEI 2207
            + + YYFR+GC  ++ + PLS + ++KT D+  +N G + +  +Y +  +I
Sbjct:  891 IQKIYYFRVGCQTKHFECPLSPLLLYKTSDKKKQNFGLLRIPDKYRNTVDI 941

HSP 3 Score: 61.6178 bits (148), Expect = 3.415e-9
Identity = 28/41 (68.29%), Postives = 36/41 (87.80%), Query Frame = 3 
Query: 3114 SSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFEC 3236
            SS +++ ++K FS+EEL  EMANLEGLMKDL++ITQKEFEC
Sbjct: 1283 SSQSESEVTKGFSTEELSQEMANLEGLMKDLNAITQKEFEC 1323
[Close]
BLAST of Netrin receptor DCC vs. Planmine SMEST
Match: SMESG000042475.1 (SMESG000042475.1)

HSP 1 Score: 97.0561 bits (240), Expect = 1.732e-26
Identity = 77/279 (27.60%), Postives = 130/279 (46.59%), Query Frame = 1 
Query: 1213 RSIPEASITTFEFISTSNSIKISWSQPIV--PVKTYTINWGNLYPGPSKQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKEIVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIXXXXXXXXXXXXXSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDY----------SMVLEFTTQETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPN----GEIKNYLIFVTADKKLDVDNW 2001
            +SIP ++IT++     + SI++ WS P    PV TYTI WG +YPGP    +      ++I +L   T Y +KI        G   +   +T   N + +P IP+NL + ++  TW  I+W +    + + S   ++Q+ Y S      +N  +      V  I  +  AT+Y   VR   V   +  +Y          S+   F+T+  +P++ PQ+L L T+   +V + +  TK    + +SW  P         +I  Y I+ T++ K D+ NW
Sbjct:  603 KSIPPSAITSWRAKGLNTSIELQWSHPTGGGPVTTYTIEWGKVYPGPQHVTLKYPINSYLINNLELRTQYMIKIIPINGASPGMELLFSHSTGNPNIKSIP-IPLNLNINQIEKTWVVITWED---PSNDVSNTRLYQIRYSSTDKDFPSNELKNTTEKNV-QITGLRTATSYSFSVRTGDVIPPRDGEYINKEWAWSEWSLKESFSTKGERPTNSPQNLKLVTIGEPDVRNTDVYTK----VALSWSSPITNETVRYDDITRYTIYFTSEPKTDISNW 872

HSP 2 Score: 43.1282 bits (100), Expect = 1.732e-26
Identity = 16/51 (31.37%), Postives = 32/51 (62.75%), Query Frame = 3 
Query: 2055 LNRYYYFRIGCSNEYGKSPLSSIRIFKTPDENGKNGGPITLSKEYYDATEI 2207
            + + YYFR+GC  ++ + PLS + ++KT D+  +N G + +  +Y +  +I
Sbjct:  891 IQKIYYFRVGCQTKHFECPLSPLLLYKTSDKKKQNFGLLRIPDKYRNTVDI 941

HSP 3 Score: 57.7658 bits (138), Expect = 4.966e-8
Identity = 27/40 (67.50%), Postives = 35/40 (87.50%), Query Frame = 3 
Query: 3114 SSDAQNLISKAFSSEELCLEMANLEGLMKDLSSITQKEFE 3233
            SS +++ ++K FS+EEL  EMANLEGLMKDL++ITQKEFE
Sbjct: 1283 SSQSESEVTKGFSTEELSQEMANLEGLMKDLNAITQKEFE 1322
The following BLAST results are available for this feature:
BLAST of Netrin receptor DCC vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DCC2.804e-1926.64DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC... [more]
DCC8.633e-1725.09DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC... [more]
DCC1.150e-1625.09DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC... [more]
NEO12.675e-1325.10neogenin 1 [Source:HGNC Symbol;Acc:HGNC:7754][more]
DCC9.995e-1335.51DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Netrin receptor DCC vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
unc-403.147e-1023.03Unc-40 protein [Source:UniProtKB/TrEMBL;Acc:G5EF9... [more]
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BLAST of Netrin receptor DCC vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fra3.584e-1023.68gene:FBgn0011592 transcript:FBtr0087821[more]
fra3.926e-1024.06gene:FBgn0011592 transcript:FBtr0087822[more]
fra4.056e-1024.06gene:FBgn0011592 transcript:FBtr0339649[more]
Ptp69D7.897e-824.58gene:FBgn0014007 transcript:FBtr0075914[more]
Ptp69D8.101e-824.58gene:FBgn0014007 transcript:FBtr0075913[more]
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BLAST of Netrin receptor DCC vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
neo1a4.906e-1624.63neogenin 1a [Source:ZFIN;Acc:ZDB-GENE-021031-1][more]
neo1a4.423e-1523.99neogenin 1a [Source:ZFIN;Acc:ZDB-GENE-021031-1][more]
dcc6.056e-1526.42DCC netrin 1 receptor [Source:NCBI gene;Acc:569360... [more]
neo1a1.149e-1322.07neogenin 1a [Source:ZFIN;Acc:ZDB-GENE-021031-1][more]
neo1b8.633e-1224.81neogenin 1b [Source:ZFIN;Acc:ZDB-GENE-131121-320][more]
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BLAST of Netrin receptor DCC vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DCC2.929e-2226.36DCC netrin 1 receptor [Source:NCBI gene;Acc:100486... [more]
DCC1.264e-2126.24DCC netrin 1 receptor [Source:NCBI gene;Acc:100486... [more]
DCC2.672e-2126.24DCC netrin 1 receptor [Source:NCBI gene;Acc:100486... [more]
DCC2.841e-2025.00DCC netrin 1 receptor [Source:NCBI gene;Acc:100486... [more]
DCC7.113e-2025.00DCC netrin 1 receptor [Source:NCBI gene;Acc:100486... [more]
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BLAST of Netrin receptor DCC vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dcc4.025e-1925.19deleted in colorectal carcinoma [Source:MGI Symbol... [more]
Dcc3.111e-1623.38deleted in colorectal carcinoma [Source:MGI Symbol... [more]
Neo19.310e-1224.71neogenin [Source:MGI Symbol;Acc:MGI:1097159][more]
Neo11.627e-1023.99neogenin [Source:MGI Symbol;Acc:MGI:1097159][more]
Ptprq8.929e-724.90protein tyrosine phosphatase, receptor type, Q [So... [more]
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BLAST of Netrin receptor DCC vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P43146|DCC_HUMAN3.818e-1625.09Netrin receptor DCC OS=Homo sapiens OX=9606 GN=DCC... [more]
sp|Q63155|DCC_RAT1.461e-1523.38Netrin receptor DCC OS=Rattus norvegicus OX=10116 ... [more]
sp|P70211|DCC_MOUSE1.899e-1523.38Netrin receptor DCC OS=Mus musculus OX=10090 GN=Dc... [more]
sp|Q90610|NEO1_CHICK2.963e-1023.81Neogenin (Fragment) OS=Gallus gallus OX=9031 PE=2 ... [more]
sp|Q92859|NEO1_HUMAN3.780e-1022.85Neogenin OS=Homo sapiens OX=9606 GN=NEO1 PE=1 SV=2[more]
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BLAST of Netrin receptor DCC vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A504YMV19.559e-3827.36Netrin receptor DCC (Fragment) OS=Fasciola giganti... [more]
A0A4E0RKI99.242e-3726.71Uncharacterized protein OS=Fasciola hepatica OX=61... [more]
A0A4S2LH981.117e-3326.77Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A4S2LNQ81.275e-3326.77Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A3R7C7J38.261e-3225.82Neogenin-like protein (Fragment) OS=Clonorchis sin... [more]
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BLAST of Netrin receptor DCC vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dcc5.985e-1724.56DCC netrin 1 receptor [Source:NCBI gene;Acc:569360... [more]
neo1a3.267e-1527.34neogenin-like [Source:NCBI gene;Acc:103031419][more]
neo1a1.169e-1427.34neogenin-like [Source:NCBI gene;Acc:103031419][more]
neo1a1.198e-1427.34neogenin-like [Source:NCBI gene;Acc:103031419][more]
neo1a1.278e-1427.34neogenin-like [Source:NCBI gene;Acc:103031419][more]
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BLAST of Netrin receptor DCC vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Netrin receptor DCC vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Netrin receptor DCC vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO469611.234e-629.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Netrin receptor DCC vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dcc4.166e-1825.09DCC netrin 1 receptor [Source:NCBI gene;Acc:101164... [more]
dcc6.115e-1825.09DCC netrin 1 receptor [Source:NCBI gene;Acc:101164... [more]
neo1b1.273e-1526.16neogenin 1 [Source:NCBI gene;Acc:101164964][more]
neo1b2.997e-1526.39neogenin 1 [Source:NCBI gene;Acc:101164964][more]
neo1b3.307e-1526.39neogenin 1 [Source:NCBI gene;Acc:101164964][more]
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BLAST of Netrin receptor DCC vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000056891.10.000e+099.70SMESG000056891.1[more]
SMESG000056891.10.000e+099.70SMESG000056891.1[more]
SMESG000042475.11.345e-2627.60SMESG000042475.1[more]
SMESG000042475.11.732e-2627.60SMESG000042475.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014869 ID=SMED30014869|Name=Netrin receptor DCC|organism=Schmidtea mediterranea sexual|type=transcript|length=3301bp
CATTTTTTAATAATGAAAAATATATTTTGGATAATTAATTTTTTGGCAAT
TTTGGATCATTATTTATTTTATTGTATTGAATATAATCCTTTCACTATTC
TGGTTAATAGAAATTCTCACTTATCGATTTCGTGTTTCTTGTCAGATAAT
GATACCAACACAAAATGGCTTACATTTAATACAAATTTCGAAATCACAGA
CTTGCATAATGATTCTCATCACACAATCAGTCCAAATGGAACTCTAAAAA
TATTTAATTTTAAAAATACGAAATTATATTATCAATGTGTTTCTGTTAGT
AAAACTCAAATTTTATTTGAAAAAATCTTTCAAATTGTTTCTATTGAACA
TTTATTTAATAATAATTTGTTAAATTTTGAACAAATTTTCAAACTGTCTA
AACCGATTCTATTTACCAGTAAATTAGTAGTCGGAAAAAACACGAAATTA
ATATGGGTTATGTGGAAAAACAATAGATTTTATGATATTTCATTGTCCAA
TAAAATTGTCCAGTTTGATAGTAGCATAAAAGTTATGATTTTATCATTAA
ACAATGTTCTCAGTTTCGTAGCTTGTTTAAAGCAAACAATTACAAATTTA
ATTATTACCTGTGATAAGCCTCATTTCATTCGCTCTTCGAAATTAGATGA
GCACTCGAAAGTGATGTATTCAGAAGTGAATGATTATGTCATTCTACAAT
GCAGAAATAGCAGTGACAATCACAAATATCGGTGGTTTAAAAATGGGAAA
TTAATTGAATTTGGAGAAAGAATTACAAATTATGGTAATATAATTTCAAT
CAGGAACATTACTGTAGATGATTATGGATATTATCAATGTTACATTAGCA
AGCCTTTTACTTTGCCTTATAAATTGTCTATTTTTTTAATTAATTTTTAT
AACTCATCGGATTTATTTCACTCGTTTGTAAAGATGAATGATAAAAAATC
TCCTTTAATTTTGCCTTGTAAACATCATTCTCCCGGAACTCCTTCATTCA
TTTACTGGAACCTCGACAAAATATCATCATTTTCTCAATTGTTAAATGTG
ACAAATCTTTCACCAAAATTATCAGATCAAACTTCTGCACTGTTTCAATG
CTTGATCAACGATAGTGATCAATTACATGTTTTTTCATACTTTTTACAAA
GCAATCATCACAATGATAAAATATCGGGCGATTCCGAAAATAAGCAAATC
ATATTAAAGAAACGGAGTATTCCTGAAGCTAGTATAACTACTTTTGAATT
TATATCCACATCAAACAGCATCAAGATCAGTTGGTCACAGCCGATTGTGC
CGGTGAAAACCTACACGATCAACTGGGGCAACTTGTATCCGGGTCCGAGC
AAACAAATCATCAGTGGAAAGGAAACGAAATTCGTTATTGAATCATTAAC
TCCATCTACCAATTACTTTGTTAAAATTGACATTGATACAGTCAAGGGCA
TCGGAAAATCATATGTTCAACCGATCACGACTAAAAAAGAAAATAAAGAA
ATTGTTCCGAAAATCCCAGTAAATTTAAAATTGGTTGAAGTTGGTGATAC
CTGGGCAAAAATATCTTGGAACGAAGATTACATTAAAAATGGCGAAGAAT
CTAAAAATACTATTTTTCAAGTTGAATATTATTCTATTCGAAATCAAAAC
AACAACAATCACAACCGACTGAATTTGTCTTCAACAGTTATCAATATCAA
AAACATGAATCCAGCGACAACGTACGAAATAATGGTGAGAAACTGCTTGG
TAAATTCTTCAAAATGCAGTGACTATTCAATGGTTTTGGAATTTACGACT
CAAGAGACCAAACCCAGTGATCCACCGCAGCATCTTACTCTATCAACAGT
TCAGATCAAAAATGTACCATCGGATAATACTCTAACGAAAAACAGGTTTG
CCATTCAAGTCTCTTGGCAGCCACCTAAAAAACCAAATGGAGAAATAAAA
AATTATCTGATATTTGTCACAGCTGATAAAAAGCTGGATGTTGATAATTG
GGGAGAAAGAACTGTCAGTGGAAAGGCTTAAATACGGTGATCGACAGACT
TGACCTAAATAGGTATTATTATTTCCGAATTGGCTGTAGCAATGAATATG
GGAAAAGTCCATTGTCATCTATCAGAATATTCAAAACTCCAGATGAAAAT
GGGAAAAATGGTGGACCAATAACACTGTCGAAAGAATATTATGACGCCAC
AGAAATTACAGAGGAGTTGAAAATCCAAACTTCCAATGAAAGAGGAAATG
ATAACTTGGTTGACACGAGTACCAACAACAATGAAACTAAAAATAAAACC
CTAACTAAACTTTCTTTGACAAATTACAAATGGTGGATTATCATTGGAAT
TGTTTTTGGAGCGATTTTAGTGTTTATATTGATAATATTGTTTTTGGTAG
CTGCCAAATGCAGAAATGAAAACATTCCTTATGAAAATGGAATCAAAATT
ATGAAAGGTAAAAATGCCTGCGATGTCGATTATATGAATTCGGGAAAAGA
AAACATAAAATTTATAAATAAAGTTCCGATTTTAACCACTCCTGATTTAT
TTCGACATACGAATGATCAGAATTGTCATCAAAATTACTTAGAAATGGAA
GAACGGACGGATTCTCCCAATTCGTTTTCATCGAATAAAGCTTTTCCATC
ACAAAGTCACAATACGAAATTTACTAGTCAGCCGAACTACCATGGCATAT
CAGGTCACTATACCCCTCCAGGTCTTATCCATCAGCAGAACATGGTAATG
ACAACAAGTCAATTAACTAGCAATTCTAATGAAAGACAATTTTATCAAGT
TCCTTTTATGCATCATATGGGCCATAATCAAATGAATGTATTCACAAGTT
CGGCACCTAGAGTTAATGCAGCGGCGTCCGATTTCAACTCTATAAATATA
CCTTCCCCAATTTCTGGTTACAGTGATTTCACGAGTAGTCAAGCTACGGT
TTTATATGATACTTCAACAGCTAAATCATCAGGTGGAAAATCCAGTCTCA
GTGGATCAGGCTCCTATAACAACGGGTTAGCTAGTAAAGCTCCTTTGGTT
AATGAACCAATAAATGAAGGAATGAATAATTGTGAAAAGTCTACAGAAAT
AGAAAATAATAAATCCAGTGATGCTCAAAATTTAATTTCAAAAGCATTCA
GCAGCGAAGAGCTGTGTTTGGAAATGGCGAATCTCGAAGGTCTCATGAAA
GATCTAAGTAGTATTACGCAAAAAGAATTTGAGTGTTGAATCATCCAGAA
AATCAAATCAGTGTCGCATTTAATGAATTTTTATAAAAAACTTGTTTGCA
T
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protein sequence of SMED30014869-orf-1

>SMED30014869-orf-1 ID=SMED30014869-orf-1|Name=SMED30014869-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=677bp
HFLIMKNIFWIINFLAILDHYLFYCIEYNPFTILVNRNSHLSISCFLSDN
DTNTKWLTFNTNFEITDLHNDSHHTISPNGTLKIFNFKNTKLYYQCVSVS
KTQILFEKIFQIVSIEHLFNNNLLNFEQIFKLSKPILFTSKLVVGKNTKL
IWVMWKNNRFYDISLSNKIVQFDSSIKVMILSLNNVLSFVACLKQTITNL
IITCDKPHFIRSSKLDEHSKVMYSEVNDYVILQCRNSSDNHKYRWFKNGK
LIEFGERITNYGNIISIRNITVDDYGYYQCYISKPFTLPYKLSIFLINFY
NSSDLFHSFVKMNDKKSPLILPCKHHSPGTPSFIYWNLDKISSFSQLLNV
TNLSPKLSDQTSALFQCLINDSDQLHVFSYFLQSNHHNDKISGDSENKQI
ILKKRSIPEASITTFEFISTSNSIKISWSQPIVPVKTYTINWGNLYPGPS
KQIISGKETKFVIESLTPSTNYFVKIDIDTVKGIGKSYVQPITTKKENKE
IVPKIPVNLKLVEVGDTWAKISWNEDYIKNGEESKNTIFQVEYYSIRNQN
NNNHNRLNLSSTVINIKNMNPATTYEIMVRNCLVNSSKCSDYSMVLEFTT
QETKPSDPPQHLTLSTVQIKNVPSDNTLTKNRFAIQVSWQPPKKPNGEIK
NYLIFVTADKKLDVDNWGERTVSGKA*
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protein sequence of SMED30014869-orf-2

>SMED30014869-orf-2 ID=SMED30014869-orf-2|Name=SMED30014869-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=263bp
MKGKNACDVDYMNSGKENIKFINKVPILTTPDLFRHTNDQNCHQNYLEME
ERTDSPNSFSSNKAFPSQSHNTKFTSQPNYHGISGHYTPPGLIHQQNMVM
TTSQLTSNSNERQFYQVPFMHHMGHNQMNVFTSSAPRVNAAASDFNSINI
PSPISGYSDFTSSQATVLYDTSTAKSSGGKSSLSGSGSYNNGLASKAPLV
NEPINEGMNNCEKSTEIENNKSSDAQNLISKAFSSEELCLEMANLEGLMK
DLSSITQKEFEC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005887integral component of plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0007399nervous system development
GO:0007411axon guidance
GO:0030513positive regulation of BMP signaling pathway
GO:0055072iron ion homeostasis
Vocabulary: molecular function
TermDefinition
GO:0038023signaling receptor activity
GO:0005515protein binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR036116FN3_sf
IPR036179Ig-like_dom_sf
IPR003598Ig_sub2
IPR003961FN3_dom
IPR013783Ig-like_fold
IPR007110Ig-like_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003961Fibronectin type IIISMARTSM00060FN3_2coord: 503..587
e-value: 0.0072
score: 25.5
coord: 408..485
e-value: 0.34
score: 20.0
IPR003961Fibronectin type IIIPFAMPF00041fn3coord: 414..485
e-value: 1.5E-7
score: 31.7
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 622..677
score: 9.113
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 408..497
score: 11.606
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 505..603
score: 13.799
IPR003961Fibronectin type IIICDDcd00063FN3coord: 420..476
e-value: 6.05176E-6
score: 43.2539
IPR003961Fibronectin type IIICDDcd00063FN3coord: 503..600
e-value: 5.16896E-8
score: 49.0319
IPR003961Fibronectin type IIICDDcd00063FN3coord: 607..669
e-value: 0.00607982
score: 34.3943
IPR003598Immunoglobulin subtype 2SMARTSM00408igc2_5coord: 225..287
e-value: 2.8E-6
score: 36.9
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 218..297
e-value: 8.3E-10
score: 40.6
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 417..498
e-value: 1.9E-9
score: 39.4
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 499..604
e-value: 2.0E-12
score: 49.1
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 605..676
e-value: 6.9E-8
score: 34.8
IPR007110Immunoglobulin-like domainPFAMPF13895Ig_2coord: 225..283
e-value: 1.6E-7
score: 31.5
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 207..293
score: 9.246
NoneNo IPR availablePANTHERPTHR46957FAMILY NOT NAMEDcoord: 538..657
NoneNo IPR availablePANTHERPTHR46957FAMILY NOT NAMEDcoord: 348..531
NoneNo IPR availablePANTHERPTHR46957:SF3coord: 538..657
NoneNo IPR availablePANTHERPTHR46957:SF3coord: 348..531
NoneNo IPR availableCDDcd00096Igcoord: 230..283
e-value: 2.58105E-5
score: 40.6885
IPR036116Fibronectin type III superfamilySUPERFAMILYSSF49265Fibronectin type IIIcoord: 502..659
IPR036116Fibronectin type III superfamilySUPERFAMILYSSF49265Fibronectin type IIIcoord: 419..495
IPR036179Immunoglobulin-like domain superfamilySUPERFAMILYSSF48726Immunoglobulincoord: 220..288