Aldolase_II domain-containing protein

Overview


Name	Aldolase_II domain-containing protein
Smed ID	SMED30014826
Length (bp)	879

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Aldolase_II domain-containing protein (SMED30014826) t-SNE clustered cells

Violin plots show distribution of expression levels for Aldolase_II domain-containing protein (SMED30014826) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Aldolase_II domain-containing protein (SMED30014826) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Aldolase_II domain-containing protein (SMED30014826) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30014826

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30014826	SMESG000044944.1	SmedASXL_013533	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
epidermis	SMED30014826	SMESG000044944.1	dd_Smed_v4_11759_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30014826	SMESG000044944.1	dd_Smed_v4_11759_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Aldolase_II domain-containing protein vs. Ensembl Human
Match: ADD3 (adducin 3 [Source:HGNC Symbol;Acc:HGNC:245])

HSP 1 Score: 72.0182 bits (175), Expect = 1.568e-13
Identity = 73/276 (26.45%), Postives = 131/276 (47.46%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNI-VFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + SN +++N+     D   T LK     F  H  + +T  + +C + I+      +S    G++PISQESLLL      ++ +Y+        +  S E+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+ L+      N+ V   ++ K    T+   G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLLG-----DVAYYD--------YQGSLEE------QEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGSHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

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Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNI-VFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + SN +++N+     D   T LK     F  H  + +T  + +C + I+      +S    G++PISQESLLL      ++ +Y+        +  S E+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+ L+      N+ V   ++ K    T+   G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLLG-----DVAYYD--------YQGSLEE------QEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGSHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Human
Match: ADD3 (adducin 3 [Source:HGNC Symbol;Acc:HGNC:245])

HSP 1 Score: 71.633 bits (174), Expect = 2.534e-13
Identity = 73/276 (26.45%), Postives = 131/276 (47.46%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNI-VFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + SN +++N+     D   T LK     F  H  + +T  + +C + I+      +S    G++PISQESLLL      ++ +Y+        +  S E+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+ L+      N+ V   ++ K    T+   G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLLG-----DVAYYD--------YQGSLEE------QEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGSHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Human
Match: ADD1 (adducin 1 [Source:HGNC Symbol;Acc:HGNC:243])

HSP 1 Score: 57.3806 bits (137), Expect = 1.179e-8
Identity = 68/275 (24.73%), Postives = 122/275 (44.36%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIK-HSIAKNFIIVNNPKIKSDNSPSNFLELNL-----DNFPTELK--SISFLIHFLV-QNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL   +++  L  W +     I+ + +S  ++F+IV    + S+ + S+ +++NL     D   T L      F +H  +     + +C + I+      +S    GL+PIS E+L L      E+ +++            DE+       K  I+ N    K+  + ++N G +  G ++EEA++    +V AC+ QV+ L+      N+V  + E   A        +    +     S  +W  GE EFEA MR L+   Y TGY ++
Sbjct:  145 LRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLG-----EVAYHDYHGILV------DEEE------KVLIQKNLGP-KSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSR-----SPGSPVGEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYR 396

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Human
Match: ADD1 (adducin 1 [Source:HGNC Symbol;Acc:HGNC:243])

HSP 1 Score: 57.3806 bits (137), Expect = 1.211e-8
Identity = 68/275 (24.73%), Postives = 122/275 (44.36%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIK-HSIAKNFIIVNNPKIKSDNSPSNFLELNL-----DNFPTELK--SISFLIHFLV-QNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL   +++  L  W +     I+ + +S  ++F+IV    + S+ + S+ +++NL     D   T L      F +H  +     + +C + I+      +S    GL+PIS E+L L      E+ +++            DE+       K  I+ N    K+  + ++N G +  G ++EEA++    +V AC+ QV+ L+      N+V  + E   A        +    +     S  +W  GE EFEA MR L+   Y TGY ++
Sbjct:  145 LRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLG-----EVAYHDYHGILV------DEEE------KVLIQKNLGP-KSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSR-----SPGSPVGEGTGSPPKWQIGEQEFEALMRMLDNLGYRTGYPYR 396

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BLAST of Aldolase_II domain-containing protein vs. Ensembl Celegans
Match: add-2 (Adducin-related protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20952])

HSP 1 Score: 93.9745 bits (232), Expect = 3.495e-22
Identity = 66/269 (24.54%), Postives = 134/269 (49.81%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISF-------LIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITG 829
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ S+ S S+ ++++LD    +  S +F       ++H  + N     +C + ++H  VV +S    GL+PISQES+++      ++ ++E       +   +       LL++        +   N + ++N G +V G +IE A      ++ AC+TQ++     ++ N+ FP++ +   +  +   G   V   N   + ++W  GELE++A MRQL+   Y+TG
Sbjct:   41 RNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMIVG-----DVGYHEYRGILIDEAERA-------LLVR-------DLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTG 290

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Celegans
Match: add-2 (Adducin-related protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20952])

HSP 1 Score: 92.0485 bits (227), Expect = 1.095e-20
Identity = 66/269 (24.54%), Postives = 134/269 (49.81%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISF-------LIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITG 829
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ S+ S S+ ++++LD    +  S +F       ++H  + N     +C + ++H  VV +S    GL+PISQES++     + ++ ++E       +   +       LL++        +   N + ++N G +V G +IE A      ++ AC+TQ++     ++ N+ FP++ +   +  +   G   V   N   + ++W  GELE++A MRQL+   Y+TG
Sbjct:  358 RNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMI-----VGDVGYHEYRGILIDEAERA-------LLVR-------DLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTG 607

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Celegans
Match: add-2 (Adducin-related protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20952])

HSP 1 Score: 92.0485 bits (227), Expect = 1.095e-20
Identity = 66/269 (24.54%), Postives = 134/269 (49.81%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISF-------LIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITG 829
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ S+ S S+ ++++LD    +  S +F       ++H  + N     +C + ++H  VV +S    GL+PISQES++     + ++ ++E       +   +       LL++        +   N + ++N G +V G +IE A      ++ AC+TQ++     ++ N+ FP++ +   +  +   G   V   N   + ++W  GELE++A MRQL+   Y+TG
Sbjct:  358 RNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMI-----VGDVGYHEYRGILIDEAERA-------LLVR-------DLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTG 607

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Celegans
Match: add-2 (Adducin-related protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q20952])

HSP 1 Score: 92.0485 bits (227), Expect = 1.095e-20
Identity = 66/269 (24.54%), Postives = 134/269 (49.81%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISF-------LIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITG 829
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ S+ S S+ ++++LD    +  S +F       ++H  + N     +C + ++H  VV +S    GL+PISQES++     + ++ ++E       +   +       LL++        +   N + ++N G +V G +IE A      ++ AC+TQ++     ++ N+ FP++ +   +  +   G   V   N   + ++W  GELE++A MRQL+   Y+TG
Sbjct:  358 RNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMI-----VGDVGYHEYRGILIDEAERA-------LLVR-------DLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTG 607

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BLAST of Aldolase_II domain-containing protein vs. Ensembl Celegans
Match: add-1 (Adducin-related protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U9K0])

HSP 1 Score: 68.5514 bits (166), Expect = 8.954e-13
Identity = 69/279 (24.73%), Postives = 124/279 (44.44%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-----------PKIKSDNSPSNFLELNLDNFPTELKSISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKS---HEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            ++KL CL ++  L  W +G    IS + +   N  ++N              +K D    N   L+       +   +FL+H  +       +C L ++   V  ++    GL+P+ +E+++L     H+  +I                D+D  FD ++       A +   N +F++N G LV G TIE A F     V AC+TQV+ +      N++ P E+   AI+    +  +   L  N    + W  GELE+E+ MR L+++++ TG+ ++
Sbjct:  124 RNKLACLFRLADLFQWSQGIHNEISYRTNDEDNTFLMNPFGLLYHEITAATIVKID---ENGKILDCGTLKAGVNQPAFLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVLGPVGYHDYQDI---------------GDDDIQFDEII-------ANLGDKNVLFLRNQGFLVVGDTIEHATFLANNTVIACETQVRAARA-GLDNLIIPEEK---AIQRAFRNSRNTNSLKRN--GTVDWRVGELEWESWMRVLDHANFQTGHVYR 371

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BLAST of Aldolase_II domain-containing protein vs. Ensembl Fly
Match: hts (gene:FBgn0263391 transcript:FBtr0309105)

HSP 1 Score: 68.9366 bits (167), Expect = 7.691e-13
Identity = 74/297 (24.92%), Postives = 131/297 (44.11%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKI-KSDNSPSNFLELNLDNFPTELKSISF---LIHFLVQNTVNC-----QCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNK-IFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAI------------KTILLDGTSNVVLINNQK----------SELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL    ++  L  W +G    I+ +  + + + +VN   +   + + S   ++++     E  + +F     HF++ + V+      +CA+ I  + VV IS    GL+P+++++ +L   EI    +  LF+E                  + + ++  ++  N+K I + N G L  G TIEEA+F    +V AC+TQ+KL   +   N+V   EES+ AI            K       +       +K          S  +W  G  EFEA MR L+ + Y TGY ++
Sbjct:  119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNFGGNKSHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL--GEITTHAYTGLFDE------------------EERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLP-VGLDNLVLIPEESRKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVGSPPKWRVGGAEFEALMRMLDNAGYRTGYIYR 394

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Fly
Match: hts (gene:FBgn0263391 transcript:FBtr0309103)

HSP 1 Score: 68.9366 bits (167), Expect = 7.691e-13
Identity = 74/297 (24.92%), Postives = 131/297 (44.11%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKI-KSDNSPSNFLELNLDNFPTELKSISF---LIHFLVQNTVNC-----QCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNK-IFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAI------------KTILLDGTSNVVLINNQK----------SELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL    ++  L  W +G    I+ +  + + + +VN   +   + + S   ++++     E  + +F     HF++ + V+      +CA+ I  + VV IS    GL+P+++++ +L   EI    +  LF+E                  + + ++  ++  N+K I + N G L  G TIEEA+F    +V AC+TQ+KL   +   N+V   EES+ AI            K       +       +K          S  +W  G  EFEA MR L+ + Y TGY ++
Sbjct:  119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNFGGNKSHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL--GEITTHAYTGLFDE------------------EERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLP-VGLDNLVLIPEESRKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVGSPPKWRVGGAEFEALMRMLDNAGYRTGYIYR 394

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Fly
Match: hts (gene:FBgn0263391 transcript:FBtr0309107)

HSP 1 Score: 68.9366 bits (167), Expect = 7.691e-13
Identity = 74/297 (24.92%), Postives = 131/297 (44.11%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKI-KSDNSPSNFLELNLDNFPTELKSISF---LIHFLVQNTVNC-----QCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNK-IFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAI------------KTILLDGTSNVVLINNQK----------SELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL    ++  L  W +G    I+ +  + + + +VN   +   + + S   ++++     E  + +F     HF++ + V+      +CA+ I  + VV IS    GL+P+++++ +L   EI    +  LF+E                  + + ++  ++  N+K I + N G L  G TIEEA+F    +V AC+TQ+KL   +   N+V   EES+ AI            K       +       +K          S  +W  G  EFEA MR L+ + Y TGY ++
Sbjct:  119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNFGGNKSHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVL--GEITTHAYTGLFDE------------------EERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLP-VGLDNLVLIPEESRKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVGSPPKWRVGGAEFEALMRMLDNAGYRTGYIYR 394

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Fly
Match: hts (gene:FBgn0263391 transcript:FBtr0309102)

HSP 1 Score: 68.5514 bits (166), Expect = 1.417e-12
Identity = 75/300 (25.00%), Postives = 131/300 (43.67%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKI-KSDNSPSNFLELNLDNFPTELKSISF---LIHFLVQNTVNC-----QCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNK-IFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAI-------------------------KTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL    ++  L  W +G    I+ +  + + + +VN   +   + + S   ++++     E  + +F     HF++ + V+      +CA+ I  + VV IS    GL+P+++++ +L   EI    +  LF+E                  + + ++  ++  N+K I + N G L  G TIEEA+F    +V AC+TQ+KL   +   N+V   EES+ AI                          T   D    V  +    S  +W  G  EFEA MR L+ + Y TGY ++
Sbjct:  119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTNFGGNKSHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLG--EITTHAYTGLFDE------------------EERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLP-VGLDNLVLIPEESRKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVG---SPPKWRVGGAEFEALMRMLDNAGYRTGYIYR 394

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Fly
Match: hts (gene:FBgn0263391 transcript:FBtr0309115)

HSP 1 Score: 68.1662 bits (165), Expect = 1.584e-12
Identity = 63/224 (28.12%), Postives = 100/224 (44.64%), Query Frame = 2

Query:  251 FLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNK-IFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAI-------------------------KTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            F++H +V     + +CA+ I  + VV IS    GL+P+++++ +L   EI    +  LF+E                  + + ++  ++  N+K I + N G L  G TIEEA+F    +V AC+TQ+KL   +   N+V   EES+ AI                          T   D    V  +    S  +W  G  EFEA MR L+ + Y TGY ++
Sbjct:  195 FVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLG--EITTHAYTGLFDE------------------EERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLL-PVGLDNLVLIPEESRKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVG---SPPKWRVGGAEFEALMRMLDNAGYRTGYIYR 394

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BLAST of Aldolase_II domain-containing protein vs. Ensembl Zebrafish
Match: add3a (adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-030131-2721])

HSP 1 Score: 75.0998 bits (183), Expect = 9.685e-15
Identity = 71/278 (25.54%), Postives = 127/278 (45.68%), Query Frame = 2

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L++I  L +W      +I+++ S  ++ I++    +  ++ S SN +++N+     D   T L+  +  F  H  + +   + +C + I+      +S    GL+PISQE+L+L      +I +Y     +    +  +E          ++++  A+    K+ + +N G +  G TIEEA+       YAC+ QV    C       IV   E+ K   + +   G        N  S+ +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  136 QTRCKLASLYRIVDLFSWAHFASCYITVRVSKEQDHILIIPRGLSFAEASASNLVKVNILGDVIDQGSTNLRIDAAGFSPHAAIYSIRPDVRCIVHISTPATAAVSSMKCGLLPISQEALILG-----DIAYYN----YQGSLDEQEE----------RVELQKALGPTAKVLVLRNHGIVALGETIEEAFHYIYGAQYACEIQVNAFSCAGGMENLIVLDLEKFKARTQGVAQVGV-------NMGSQQKWRLGELEFESLMRMLDNLGYRTGYTYR 387

[Close]

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L++I  L +W      +I+++ S  ++ I++    +  ++ S SN +++N+     D   T L+  +  F  H  + +   + +C + I+      +S    GL+PISQE+L+L      +I +Y     +    +  +E          ++++  A+    K+ + +N G +  G TIEEA+       YAC+ QV    C       IV   E+ K   + +   G        N  S+ +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  136 QTRCKLASLYRIVDLFSWAHFASCYITVRVSKEQDHILIIPRGLSFAEASASNLVKVNILGDVIDQGSTNLRIDAAGFSPHAAIYSIRPDVRCIVHISTPATAAVSSMKCGLLPISQEALILG-----DIAYYN----YQGSLDEQEE----------RVELQKALGPTAKVLVLRNHGIVALGETIEEAFHYIYGAQYACEIQVNAFSCAGGMENLIVLDLEKFKARTQGVAQVGV-------NMGSQQKWRLGELEFESLMRMLDNLGYRTGYTYR 387

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Zebrafish
Match: add3a (adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-030131-2721])

HSP 1 Score: 74.7146 bits (182), Expect = 1.265e-14
Identity = 71/278 (25.54%), Postives = 127/278 (45.68%), Query Frame = 2

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L++I  L +W      +I+++ S  ++ I++    +  ++ S SN +++N+     D   T L+  +  F  H  + +   + +C + I+      +S    GL+PISQE+L+L      +I +Y     +    +  +E          ++++  A+    K+ + +N G +  G TIEEA+       YAC+ QV    C       IV   E+ K   + +   G        N  S+ +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  136 QTRCKLASLYRIVDLFSWAHFASCYITVRVSKEQDHILIIPRGLSFAEASASNLVKVNILGDVIDQGSTNLRIDAAGFSPHAAIYSIRPDVRCIVHISTPATAAVSSMKCGLLPISQEALILG-----DIAYYN----YQGSLDEQEE----------RVELQKALGPTAKVLVLRNHGIVALGETIEEAFHYIYGAQYACEIQVNAFSCAGGMENLIVLDLEKFKARTQGVAQVGV-------NMGSQQKWRLGELEFESLMRMLDNLGYRTGYTYR 387

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Zebrafish
Match: add3a (adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-030131-2721])

HSP 1 Score: 74.7146 bits (182), Expect = 1.351e-14
Identity = 71/278 (25.54%), Postives = 127/278 (45.68%), Query Frame = 2

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L++I  L +W      +I+++ S  ++ I++    +  ++ S SN +++N+     D   T L+  +  F  H  + +   + +C + I+      +S    GL+PISQE+L+L      +I +Y     +    +  +E          ++++  A+    K+ + +N G +  G TIEEA+       YAC+ QV    C       IV   E+ K   + +   G        N  S+ +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  136 QTRCKLASLYRIVDLFSWAHFASCYITVRVSKEQDHILIIPRGLSFAEASASNLVKVNILGDVIDQGSTNLRIDAAGFSPHAAIYSIRPDVRCIVHISTPATAAVSSMKCGLLPISQEALILG-----DIAYYN----YQGSLDEQEE----------RVELQKALGPTAKVLVLRNHGIVALGETIEEAFHYIYGAQYACEIQVNAFSCAGGMENLIVLDLEKFKARTQGVAQVGV-------NMGSQQKWRLGELEFESLMRMLDNLGYRTGYTYR 387

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Zebrafish
Match: add3a (adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-030131-2721])

HSP 1 Score: 74.7146 bits (182), Expect = 1.351e-14
Identity = 71/278 (25.54%), Postives = 127/278 (45.68%), Query Frame = 2

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L++I  L +W      +I+++ S  ++ I++    +  ++ S SN +++N+     D   T L+  +  F  H  + +   + +C + I+      +S    GL+PISQE+L+L      +I +Y     +    +  +E          ++++  A+    K+ + +N G +  G TIEEA+       YAC+ QV    C       IV   E+ K   + +   G        N  S+ +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  136 QTRCKLASLYRIVDLFSWAHFASCYITVRVSKEQDHILIIPRGLSFAEASASNLVKVNILGDVIDQGSTNLRIDAAGFSPHAAIYSIRPDVRCIVHISTPATAAVSSMKCGLLPISQEALILG-----DIAYYN----YQGSLDEQEE----------RVELQKALGPTAKVLVLRNHGIVALGETIEEAFHYIYGAQYACEIQVNAFSCAGGMENLIVLDLEKFKARTQGVAQVGV-------NMGSQQKWRLGELEFESLMRMLDNLGYRTGYTYR 387

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Xenopus
Match: atr (ATR serine/threonine kinase [Source:Xenbase;Acc:XB-GENE-1012722])

HSP 1 Score: 71.2478 bits (173), Expect = 2.822e-13
Identity = 66/275 (24.00%), Postives = 121/275 (44.00%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNLDNFPTELKSI-------SFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  ++++  L  W    + +I+++ +  ++ I++    +  S+ S SN ++LN+     E  S         F  H  +  T  + +CA+ I+      +S    G++PISQE+LLL      ++ +Y     +    +  +E      ++    KV         + ++N G L  G ++EEA+     V  AC+ QV         N  ++   E+ K     +   G   V    N + + +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  136 RCKLASMYRLADLFGWAHLAKAYITVRVTKEQDHILIMPRGLSFSEASASNLVKLNIIGEVVEQGSTNLQIDPSGFSPHAAIYATRPDVRCAIHIHTPAAAAVSSMKCGILPISQEALLLG-----DVAYYN----YQGSLDEQEERIELQKVLGASAKV---------LVLRNHGVLALGESLEEAFHYIFNVQLACEVQVHALAGAGGVNNLLLLDLEKFKPTTYCVAAAGGGGV----NMEGDHKWKVGELEFESLMRMLDNLGYRTGYAYR 388

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Xenopus
Match: atr (ATR serine/threonine kinase [Source:Xenbase;Acc:XB-GENE-1012722])

HSP 1 Score: 70.8626 bits (172), Expect = 3.916e-13
Identity = 66/276 (23.91%), Postives = 124/276 (44.93%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNLDNFPTELKSI-------SFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  ++++  L  W    + +I+++ +  ++ I++    +  S+ S SN ++LN+     E  S         F  H  +  T  + +CA+ I+      +S    G++PISQE+LLL      ++ +Y     +    +  +E          +I++   +  + K+ + +N G L  G ++EEA+     V  AC+ QV         N  ++   E+ K     +   G   V    N + + +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  133 RCKLASMYRLADLFGWAHLAKAYITVRVTKEQDHILIMPRGLSFSEASASNLVKLNIIGEVVEQGSTNLQIDPSGFSPHAAIYATRPDVRCAIHIHTPAAAAVSSMKCGILPISQEALLLG-----DVAYYN----YQGSLDEQEE----------RIELQKVLGASAKVLVLRNHGVLALGESLEEAFHYIFNVQLACEVQVHALAGAGGVNNLLLLDLEKFKPTTYCVAAAGGGGV----NMEGDHKWKVGELEFESLMRMLDNLGYRTGYAYR 385

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Xenopus
Match: atr (ATR serine/threonine kinase [Source:Xenbase;Acc:XB-GENE-1012722])

HSP 1 Score: 70.4774 bits (171), Expect = 4.115e-13
Identity = 66/276 (23.91%), Postives = 124/276 (44.93%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNLDNFPTELKSI-------SFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  ++++  L  W    + +I+++ +  ++ I++    +  S+ S SN ++LN+     E  S         F  H  +  T  + +CA+ I+      +S    G++PISQE+LLL      ++ +Y     +    +  +E          +I++   +  + K+ + +N G L  G ++EEA+     V  AC+ QV         N  ++   E+ K     +   G   V    N + + +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  137 RCKLASMYRLADLFGWAHLAKAYITVRVTKEQDHILIMPRGLSFSEASASNLVKLNIIGEVVEQGSTNLQIDPSGFSPHAAIYATRPDVRCAIHIHTPAAAAVSSMKCGILPISQEALLLG-----DVAYYN----YQGSLDEQEE----------RIELQKVLGASAKVLVLRNHGVLALGESLEEAFHYIFNVQLACEVQVHALAGAGGVNNLLLLDLEKFKPTTYCVAAAGGGGV----NMEGDHKWKVGELEFESLMRMLDNLGYRTGYAYR 389

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Xenopus
Match: atr (ATR serine/threonine kinase [Source:Xenbase;Acc:XB-GENE-1012722])

HSP 1 Score: 70.4774 bits (171), Expect = 4.634e-13
Identity = 66/276 (23.91%), Postives = 124/276 (44.93%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNLDNFPTELKSI-------SFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  ++++  L  W    + +I+++ +  ++ I++    +  S+ S SN ++LN+     E  S         F  H  +  T  + +CA+ I+      +S    G++PISQE+LLL      ++ +Y     +    +  +E          +I++   +  + K+ + +N G L  G ++EEA+     V  AC+ QV         N  ++   E+ K     +   G   V    N + + +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  136 RCKLASMYRLADLFGWAHLAKAYITVRVTKEQDHILIMPRGLSFSEASASNLVKLNIIGEVVEQGSTNLQIDPSGFSPHAAIYATRPDVRCAIHIHTPAAAAVSSMKCGILPISQEALLLG-----DVAYYN----YQGSLDEQEE----------RIELQKVLGASAKVLVLRNHGVLALGESLEEAFHYIFNVQLACEVQVHALAGAGGVNNLLLLDLEKFKPTTYCVAAAGGGGV----NMEGDHKWKVGELEFESLMRMLDNLGYRTGYAYR 388

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Xenopus
Match: atr (ATR serine/threonine kinase [Source:Xenbase;Acc:XB-GENE-1012722])

HSP 1 Score: 70.4774 bits (171), Expect = 5.045e-13
Identity = 66/276 (23.91%), Postives = 124/276 (44.93%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNLDNFPTELKSI-------SFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  ++++  L  W    + +I+++ +  ++ I++    +  S+ S SN ++LN+     E  S         F  H  +  T  + +CA+ I+      +S    G++PISQE+LLL      ++ +Y     +    +  +E          +I++   +  + K+ + +N G L  G ++EEA+     V  AC+ QV         N  ++   E+ K     +   G   V    N + + +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  130 RCKLASMYRLADLFGWAHLAKAYITVRVTKEQDHILIMPRGLSFSEASASNLVKLNIIGEVVEQGSTNLQIDPSGFSPHAAIYATRPDVRCAIHIHTPAAAAVSSMKCGILPISQEALLLG-----DVAYYN----YQGSLDEQEE----------RIELQKVLGASAKVLVLRNHGVLALGESLEEAFHYIFNVQLACEVQVHALAGAGGVNNLLLLDLEKFKPTTYCVAAAGGGGV----NMEGDHKWKVGELEFESLMRMLDNLGYRTGYAYR 382

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Mouse
Match: Add3 (adducin 3 (gamma) [Source:MGI Symbol;Acc:MGI:1351615])

HSP 1 Score: 71.633 bits (174), Expect = 1.529e-13
Identity = 69/276 (25.00%), Postives = 129/276 (46.74%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + S  +++N+     D   T+LK     F  H  + +T  + +C + I+      +S    G++PISQESL+L      ++ +Y+          S DE+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+        +  +V   ++ K     + + G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILG-----DVAYYDYQG-------SLDEE-------EERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHGVAMSGGGGVNMASHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

[Close]

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + S  +++N+     D   T+LK     F  H  + +T  + +C + I+      +S    G++PISQESL+L      ++ +Y+          S DE+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+        +  +V   ++ K     + + G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILG-----DVAYYDYQG-------SLDEE-------EERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHGVAMSGGGGVNMASHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

[Close]

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + S  +++N+     D   T+LK     F  H  + +T  + +C + I+      +S    G++PISQESL+L      ++ +Y+          S DE+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+        +  +V   ++ K     + + G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILG-----DVAYYDYQG-------SLDEE-------EERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHGVAMSGGGGVNMASHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

[Close]

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + S  +++N+     D   T+LK     F  H  + +T  + +C + I+      +S    G++PISQESL+L      ++ +Y+          S DE+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+        +  +V   ++ K     + + G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILG-----DVAYYDYQG-------SLDEE-------EERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHGVAMSGGGGVNMASHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

[Close]

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + S  +++N+     D   T+LK     F  H  + +T  + +C + I+      +S    G++PISQESL+L      ++ +Y+          S DE+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+        +  +V   ++ K     + + G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILG-----DVAYYDYQG-------SLDEE-------EERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHGVAMSGGGGVNMASHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

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BLAST of Aldolase_II domain-containing protein vs. UniProt/SwissProt
Match: sp|Q20952|ADD2_CAEEL (Adducin-related protein 2 OS=Caenorhabditis elegans OX=6239 GN=add-2 PE=2 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.393e-19
Identity = 66/269 (24.54%), Postives = 134/269 (49.81%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISF-------LIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITG 829
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ S+ S S+ ++++LD    +  S +F       ++H  + N     +C + ++H  VV +S    GL+PISQES++     + ++ ++E       +   +       LL++        +   N + ++N G +V G +IE A      ++ AC+TQ++     ++ N+ FP++ +   +  +   G   V   N   + ++W  GELE++A MRQL+   Y+TG
Sbjct:  358 RNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMI-----VGDVGYHEYRGILIDEAERA-------LLVR-------DLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTG 607

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BLAST of Aldolase_II domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UEY8|ADDG_HUMAN (Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1)

HSP 1 Score: 71.633 bits (174), Expect = 1.217e-12
Identity = 73/276 (26.45%), Postives = 131/276 (47.46%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNI-VFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + SN +++N+     D   T LK     F  H  + +T  + +C + I+      +S    G++PISQESLLL      ++ +Y+        +  S E+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+ L+      N+ V   ++ K    T+   G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLLLG-----DVAYYD--------YQGSLEE------QEERIQLQKVLGPSCKVLVLRNHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGSHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

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BLAST of Aldolase_II domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9QYB5|ADDG_MOUSE (Gamma-adducin OS=Mus musculus OX=10090 GN=Add3 PE=1 SV=2)

HSP 1 Score: 71.2478 bits (173), Expect = 1.437e-12
Identity = 69/276 (25.00%), Postives = 129/276 (46.74%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +IS++ S  ++ II+    +  S+ + S  +++N+     D   T+LK     F  H  + +T  + +C + I+      +S    G++PISQESL+L      ++ +Y+          S DE+       + +I++   +  + K+ + +N G +  G T+EEA+     V  AC+ QV+        +  +V   ++ K     + + G   V + ++QK    W  GE+EFE  MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLADLFGWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASTLVKVNIIGEVVDQGSTDLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGILPISQESLILG-----DVAYYDYQG-------SLDEE-------EERIELQKVLGPSCKVLVLRNHGMVALGETLEEAFHYIFNVQMACEIQVQAVAGAGGVDNLLVLDLQKYKAFTHGVAMSGGGGVNMASHQK----WKVGEIEFEGLMRTLDNLGYRTGYAYR 390

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BLAST of Aldolase_II domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9U9K0|ADD1_CAEEL (Adducin-related protein 1 OS=Caenorhabditis elegans OX=6239 GN=add-1 PE=2 SV=2)

HSP 1 Score: 68.5514 bits (166), Expect = 1.470e-11
Identity = 69/279 (24.73%), Postives = 124/279 (44.44%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-----------PKIKSDNSPSNFLELNLDNFPTELKSISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKS---HEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            ++KL CL ++  L  W +G    IS + +   N  ++N              +K D    N   L+       +   +FL+H  +       +C L ++   V  ++    GL+P+ +E+++L     H+  +I                D+D  FD ++       A +   N +F++N G LV G TIE A F     V AC+TQV+ +      N++ P E+   AI+    +  +   L  N    + W  GELE+E+ MR L+++++ TG+ ++
Sbjct:  124 RNKLACLFRLADLFQWSQGIHNEISYRTNDEDNTFLMNPFGLLYHEITAATIVKID---ENGKILDCGTLKAGVNQPAFLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVLGPVGYHDYQDI---------------GDDDIQFDEII-------ANLGDKNVLFLRNQGFLVVGDTIEHATFLANNTVIACETQVRAARA-GLDNLIIPEEK---AIQRAFRNSRNTNSLKRN--GTVDWRVGELEWESWMRVLDHANFQTGHVYR 371

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BLAST of Aldolase_II domain-containing protein vs. UniProt/SwissProt
Match: sp|Q02645|HTS_DROME (Protein hu-li tai shao OS=Drosophila melanogaster OX=7227 GN=hts PE=1 SV=2)

HSP 1 Score: 68.1662 bits (165), Expect = 1.903e-11
Identity = 75/298 (25.17%), Postives = 132/298 (44.30%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPK--IKSDNSPSNFLELNLDNFPTELKSISF---LIHFLVQNTVNC-----QCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNK-IFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAI------------KTILLDGTSNVVLINNQK----------SELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL    ++  L  W +G    I+ +  + + + +VN P   +  + + S   ++++     E  + +F     HF++ + V+      +CA+ I  + VV IS    GL+P+++++ +L   EI    +  LF+E                  + + ++  ++  N+K I + N G L  G TIEEA+F    +V AC+TQ+KL   +   N+V   EES+ AI            K       +       +K          S  +W  G  EFEA MR L+ + Y TGY ++
Sbjct:  119 LRCKLAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVN-PYGLLYHEITASALNKVDMQGQIVEQGTTNFGGNKSHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLG--EITTHAYTGLFDE------------------EERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLP-VGLDNLVLIPEESRKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVGSPPKWRVGGAEFEALMRMLDNAGYRTGYIYR 394

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BLAST of Aldolase_II domain-containing protein vs. TrEMBL
Match: Q1ZXU2 (Aldolase_II domain-containing protein OS=Caenorhabditis elegans OX=6239 GN=add-2 PE=1 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.318e-18
Identity = 66/269 (24.54%), Postives = 134/269 (49.81%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISF-------LIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITG 829
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ S+ S S+ ++++LD    +  S +F       ++H  + N     +C + ++H  VV +S    GL+PISQES+++      ++ ++E       +   +       LL++        +   N + ++N G +V G +IE A      ++ AC+TQ++     ++ N+ FP++ +   +  +   G   V   N   + ++W  GELE++A MRQL+   Y+TG
Sbjct:   41 RNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMIVG-----DVGYHEYRGILIDEAERA-------LLVR-------DLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTG 290

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BLAST of Aldolase_II domain-containing protein vs. TrEMBL
Match: A0A1I7TP00 (Aldolase_II domain-containing protein OS=Caenorhabditis tropicalis OX=1561998 PE=4 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 2.182e-18
Identity = 68/272 (25.00%), Postives = 136/272 (50.00%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISF-------LIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDF 838
            ++KL  L+++  L  W +G    I+++ S   + I++N   +  ++ S S+ ++++LD    +  S SF       ++H  + N     +C + ++H  VV +S    GL+PISQE+++     + E+ ++E       +   +       LL++        +   N + ++N G +V G +IE A      ++ AC+TQVK     ++ N+ FP++ +   +  +  +G   V   N   +  +W  GELE++A MRQL+   Y+TG+++
Sbjct:  336 RNKLAALYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQFYNEVSASSLIKVDLDGTVIDGGSTSFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQEAMI-----VGEVGYHEYRGILIDEAERA-------LLIR-------DLGDRNVLILRNHGFVVCGESIEHALSLTYHLIIACETQVKAVPGGNTDNVHFPAQSAIKQVYKVASNGGGGVNRQNGHVNSTQWRKGELEWQAYMRQLDAQGYVTGHEY 588

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BLAST of Aldolase_II domain-containing protein vs. TrEMBL
Match: A0A2G5TGG3 (Aldolase_II domain-containing protein OS=Caenorhabditis nigoni OX=1611254 GN=Cni-add-2 PE=4 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 4.292e-17
Identity = 66/275 (24.00%), Postives = 138/275 (50.18%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISFLIH---FLVQNTVN-----CQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFKLK 847
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ ++ S S+ ++++LD       S  F ++   +++ + V+      +C + ++H  VV +S    GL+PISQE+++     + E+ ++E       +   +       LL++        +   + + ++N G +V G ++E A      ++ AC+TQVK     ++ N+ FP+  +   +  +  +G   V   N   +  +W  GELE++A MRQL+   Y+TG+D+  K
Sbjct:  374 RNKLAALYRLVDLFRWSQGIYNHITVRVSNDPDEILINAFGQLYNEVSASSLIKVDLDGTVINGGSTDFGVNQAGYVLHSAVHRARPEIKCVVHLHHPSVVAVSAQKCGLLPISQEAMI-----VGEVGYHEYRGILIDEAERA-------LLVR-------DLGDRHVMILRNHGFVVCGESVEHALSVTYHLIIACETQVKTVPGGNTDNVHFPAHSAIKQVYQVACNGGGGVNRQNGHVNSTQWRKGELEWQAYMRQLDAQGYVTGHDYNCK 629

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BLAST of Aldolase_II domain-containing protein vs. TrEMBL
Match: A8Y444 (Protein CBR-ADD-2 OS=Caenorhabditis briggsae OX=6238 GN=add-2 PE=4 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 5.220e-17
Identity = 65/275 (23.64%), Postives = 138/275 (50.18%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNLDNFPTELKSISFLIH---FLVQNTVN-----CQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFKLK 847
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ ++ S S+ +++++D       S  F ++   +++ + V+      +C + ++H  VV +S    GL+PISQE+++     + E+ ++E       +   +       LL++        +   + + ++N G +V G ++E A      ++ AC+TQVK     ++ N+ FP+  +   +  +  +G   V   N   +  +W  GELE++A MRQL+   Y+TG+D+  K
Sbjct:  372 RNKLAALYRLVDLFRWSQGIYNHITVRVSNDPDEILINAFGQLYNEVSASSLIKVDMDGTVINGGSTGFGVNQAGYVLHSAVHRARPEIKCVVHLHHPSVVAVSAQKCGLLPISQEAMI-----VGEVGYHEYRGILIDEAERA-------LLVR-------DLGDRHVMILRNHGFVVCGESVEHALSVTYHLIIACETQVKTVPGGNTDNVHFPAHSAIKQVYQVASNGGGGVNRQNGHVNSTQWRKGELEWQAYMRQLDAQGYVTGHDYNCK 627

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BLAST of Aldolase_II domain-containing protein vs. TrEMBL
Match: A0A2H2IJW5 (Aldolase_II domain-containing protein OS=Caenorhabditis japonica OX=281687 PE=4 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 1.338e-16
Identity = 65/271 (23.99%), Postives = 136/271 (50.18%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN-PKIKSDNSPSNFLELNL-----DNFPTE--LKSISFLIHFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYD 835
            ++KL  L+++  L  W +G    I+++ S   + I++N   ++ ++ + S+ ++++L     D   TE  +    +++H  + +   + +C + ++H  VV +S    GL+PISQE++++      ++ ++E       +   +       LL++        + + N + ++N G +V   ++E A      ++ AC+TQVK      + N+ FPS+ +   +  +   G   V   N Q +  RW  GELE++A MRQL+   Y+TG++
Sbjct:   42 RNKLASLYRLVDLFRWSQGIYNHITVRISPDTDEILINAFGQLYNEVTASSLVKVDLEGNVLDKGSTEFGVNQAGYVLHSAIHSGRPDAKCVIHLHHPSVVAVSAQKCGLLPISQEAMIVG-----DVAYHEYKGILIDEAERA-------LLIR-------DLGERNVMILRNHGFVVCAESVEHALSLTYHLIIACETQVKSVPGGCTDNVHFPSQAAVKQVYMVASHGGGGVNRENGQINSCRWRRGELEWQAYMRQLDAQGYVTGHE 293

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Cavefish
Match: add3a (adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-030131-2721])

HSP 1 Score: 63.1586 bits (152), Expect = 9.379e-11
Identity = 68/278 (24.46%), Postives = 119/278 (42.81%), Query Frame = 2

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIA------KNFIIVNNPKIKSDNSPSNFLELNLDNFPTELK--SISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L+++  L +W      +I+++++            + N   +K      N L   +D   T L+     F  H  + +   + +C + I+      +S    GL+PISQE+L+L   +I           +F    S DE        + ++++  A+  + K+ + +N G +  G TIEEA+        AC+ QV    C       IV   E+ ++  + +   G        N  S+ +W  GELEFE+ MR L+   Y TGY ++
Sbjct:  135 QTRCKLAALYRLVDLFSWAHFSSSYITVRNTFTVQHFHCSTLSLFNTFTVKV-----NILGDVVDQGSTTLRMDPAGFSPHAAIYSMRPDVRCIVHIHTPVTAAVSSMKCGLLPISQEALILG--DIA----------YFNYQGSLDE-------QEERVELQKALGPSAKVLVLRNHGVVALGETIEEAFHYIYTAQLACEIQVNAFSCAGGVENLIVLDLEKYRSRTQGVAQTGV-------NMASQNKWKIGELEFESLMRMLDNLGYRTGYAYR 381

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Cavefish
Match: add1 (adducin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-030909-2])

HSP 1 Score: 62.7734 bits (151), Expect = 1.047e-10
Identity = 70/278 (25.18%), Postives = 131/278 (47.12%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIK-HSIAKNFIIVNNPKIKSDNSPSNFLELNL-----DNFPTELK--SISFLIHFLV-QNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNIVF--PSE-ESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL   +++  L  W +     ++++ +S  + F+IV    + S+ S S+ +++NL     D   T L      F +H  +     + +C + I+      +S    GL+PIS E+L L      E+ +++            DE+   ++L++  +   + +L      ++N G +  G T+EEA++    +V AC+ QV+ L+      N+V   P++ ++++     + DGTS           L+W  GE EFEA MR L+   Y TGY ++
Sbjct:  134 LRCKLAAFYRLADLFGWSQLIYNHLTVRLNSEQERFLIVPFGLLYSEVSASSLVKINLQGEIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCIVHIHTPAGAAVSAMKCGLLPISPEALSLG-----EVAYHDYHGILV------DEEE--NVLIQKNLGPTSKVL-----ILRNHGLVSVGETVEEAFYYIHNLVRACEIQVRTLASAGGPDNLVMLDPAKYKARSRHPEPVGDGTS-----------LKWQIGEQEFEALMRMLDNLGYRTGYPYR 382

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Cavefish
Match: add3b (gamma-adducin-like [Source:NCBI gene;Acc:103046517])

HSP 1 Score: 62.3882 bits (150), Expect = 1.364e-10
Identity = 65/277 (23.47%), Postives = 121/277 (43.68%), Query Frame = 2

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNLDNFPTELKSISFLI-------HFLVQNT-VNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHS-KNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L+++  L  +      +I+++    ++ +++    +  S+ + ++ +++NL     E  S+ F +       H  V +   + +C + I+      IS    G++PIS E+LLL      E+ +       FT     D+        + ++++  A+    K+ + +N G L  G TIEEA+        AC+ QV    C     N+    +ES   +K       S       +  E+RW  GE EFE+ MR ++   Y TGY ++
Sbjct:  168 QNRCKLASLYRLLDLYGYTHCTSGYITVRVCREQDHVLILPRGLSFSEATAASLMKVNLIGHVVEHGSMGFAVDDAAFKLHAAVYSARPDAKCVIHIHTPATAAISSMKCGILPISHEALLLG-----EVSY-------FTYHGDVDDG-------QERVELQKALGPTTKVLVLRNHGLLAFGETIEEAFHYAYHSQQACEIQVCAVLCAGGVDNLCVLDKES---VKV------SPSASGETEDGEVRWRVGEAEFESLMRMMDNLGYRTGYAYR 416

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Cavefish
Match: add1 (adducin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-030909-2])

HSP 1 Score: 62.003 bits (149), Expect = 2.204e-10
Identity = 70/278 (25.18%), Postives = 131/278 (47.12%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIK-HSIAKNFIIVNNPKIKSDNSPSNFLELNL-----DNFPTELK--SISFLIHFLV-QNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNIVF--PSE-ESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL   +++  L  W +     ++++ +S  + F+IV    + S+ S S+ +++NL     D   T L      F +H  +     + +C + I+      +S    GL+PIS E+L L      E+ +++            DE+   ++L++  +   + +L      ++N G +  G T+EEA++    +V AC+ QV+ L+      N+V   P++ ++++     + DGTS           L+W  GE EFEA MR L+   Y TGY ++
Sbjct:   95 LRCKLAAFYRLADLFGWSQLIYNHLTVRLNSEQERFLIVPFGLLYSEVSASSLVKINLQGEIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCIVHIHTPAGAAVSAMKCGLLPISPEALSLG-----EVAYHDYHGILV------DEEE--NVLIQKNLGPTSKVL-----ILRNHGLVSVGETVEEAFYYIHNLVRACEIQVRTLASAGGPDNLVMLDPAKYKARSRHPEPVGDGTS-----------LKWQIGEQEFEALMRMLDNLGYRTGYPYR 343

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Cavefish
Match: add1 (adducin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-030909-2])

HSP 1 Score: 62.003 bits (149), Expect = 2.279e-10
Identity = 70/278 (25.18%), Postives = 131/278 (47.12%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIK-HSIAKNFIIVNNPKIKSDNSPSNFLELNL-----DNFPTELK--SISFLIHFLV-QNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVK-LSHCIHSKNIVF--PSE-ESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL   +++  L  W +     ++++ +S  + F+IV    + S+ S S+ +++NL     D   T L      F +H  +     + +C + I+      +S    GL+PIS E+L L      E+ +++            DE+   ++L++  +   + +L      ++N G +  G T+EEA++    +V AC+ QV+ L+      N+V   P++ ++++     + DGTS           L+W  GE EFEA MR L+   Y TGY ++
Sbjct:   95 LRCKLAAFYRLADLFGWSQLIYNHLTVRLNSEQERFLIVPFGLLYSEVSASSLVKINLQGEIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCIVHIHTPAGAAVSAMKCGLLPISPEALSLG-----EVAYHDYHGILV------DEEE--NVLIQKNLGPTSKVL-----ILRNHGLVSVGETVEEAFYYIHNLVRACEIQVRTLASAGGPDNLVMLDPAKYKARSRHPEPVGDGTS-----------LKWQIGEQEFEALMRMLDNLGYRTGYPYR 343

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Sea Lamprey
Match: add1 (adducin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-030909-2])

HSP 1 Score: 61.2326 bits (147), Expect = 6.895e-11
Identity = 69/279 (24.73%), Postives = 127/279 (45.52%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAK---NFIIVNNPKIKSDNSPSNFLELNL-----DNFPTELK--SISFLIHFLV-QNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKT--ILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            L+ KL  ++++  L  W   + I+  I   + K   +F+I+    + S+ + S+ +++NL     D   T L      F +H  +     + +C + ++      +S    GL+PISQES++L      E+ +++             E  + D   K  ++ N  +   +K+ I +N G +  G T+EEA+     +V AC+ QV+      S + V   +E K  ++T  I+  G  N+  ++       W  GE E EA MR ++   Y TGY ++
Sbjct:  145 LRCKLAAVYRLVDLYGW--SQLIYNHISARVNKEQEHFLIIPFGLLFSEVTASSLVKVNLQGEIVDRGSTNLGINQAGFTLHSAIYAARPDIKCVIHVHTPAGTAVSAMKCGLLPISQESMILG-----EVTYHDY------------EGILVDDEEKANLQKN--LGPTSKVLILRNHGLVALGETVEEAFHYLYNLVMACEVQVRTLASAGSVDNVILLDEEKLRVRTQGIVTHGNVNMAGLHT------WGVGEQELEALMRMMDSMGYRTGYAYR 396

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Nematostella
Match: EDO42734 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0I1])

HSP 1 Score: 59.6918 bits (143), Expect = 2.848e-10
Identity = 63/263 (23.95%), Postives = 119/263 (45.25%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIK------HSIAKNFIIVNNPKIKSDNSPSNFLELNLDNFPTELK--SISFLIHFLVQNTV-NCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLE 808
            L+ KL  ++++  L  W  G    I+ +      H +   F ++ N    S     +F    +D   T L       ++H  V +   +  C + I+    V ++    G++PI+QE+ +L      EI +++         + +++D+I + L +          K+  + ++N G ++ G TIEEA+    + V +C+ QV+ +      N++  SE+ +   K + + G  N   I + K   +W  GELEFEA MR L+
Sbjct:   88 LRCKLAAVYRLVDLFGWSIGIYGHITARASNDEDHYLLNPFGLLYNEVTASSLVKVDFAGNIVDGGSTNLGVNRAGLVLHSAVHSARKDIACVIHIHQPACVAVASTEYGILPITQEASMLG-----EIAYHDFRGILL---DENEKDAIINELGE----------KSKVMVLRNHGMVIAGDTIEEAFMLAHMCVLSCEYQVR-AMSAGVDNLIKVSEQVRE--KVLEVTGGEN---ITDSKGS-KWKHGELEFEAWMRMLD 325

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Nematostella
Match: EDO42733 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0I0])

HSP 1 Score: 49.2914 bits (116), Expect = 8.728e-7
Identity = 44/187 (23.53%), Postives = 88/187 (47.06%), Query Frame = 2

Query:  293 CALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSK--NIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFKLK 847
            C +++  T+V  +S    G++PIS E+       I EI ++ L +    K     E     L +    KV         + ++N+G +  G+++EEA++   L+  AC+ Q   ++ + +   N++   +E +  I   + +G      +N  K ++     ++ FEA MR L+   + TGY+F ++
Sbjct:  322 CVVVLCSTNVKAVSAMDCGVLPISHEAAA-----IGEIVYHTLGSIVLDKA----EKEALTLKLSAVDKV---------LVLRNMGAVCVGKSVEEAFYNAFLLHKACENQ---AYAVRAGINNLIKLDDEVREKIYKSVQEGDD----VNQNKRKV----ADVHFEAWMRMLDARGHKTGYEFSIQ 479

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Medaka
Match: add3b (gamma-adducin [Source:NCBI gene;Acc:101170613])

HSP 1 Score: 68.1662 bits (165), Expect = 2.081e-12
Identity = 71/286 (24.83%), Postives = 124/286 (43.36%), Query Frame = 2

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTEL--KSISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLD-----------GTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L+++  L NW R    +I+++ S  ++ I+++   +  ++ + +N +++N+     D   TEL      F  H  + +   + +C + I+      +S    G++PISQE+LLL      ++  Y     +    ++ +E   F   +    KV         + + N G L  G T+EEA+        AC+ QV    C            S NA    LLD             + VV+ N    E++W  GE EFE+ +R L+   Y TGY ++
Sbjct:  136 QSRCKLASLYRLVDLFNWARFTSAYITVRVSKEQDHILISPRGLSFAEVTAANLVKVNIVGEVVDQGSTELGIDHFGFAPHAAIYSMRPDVRCIIHIHTPATTAVSSMKCGILPISQEALLLG-----DVSCYG----YHGSLDNKEEMVEFQKALGPTSKV---------MMLSNHGLLALGETVEEAFHYVYHSQLACEIQVHSLRC------------SGNADNLTLLDRQKFKPLTQGVAAAGVVIDN----EVKWKVGEAEFESLLRMLDNLGYRTGYAYR 387

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Medaka
Match: add3b (gamma-adducin [Source:NCBI gene;Acc:101170613])

HSP 1 Score: 67.781 bits (164), Expect = 2.278e-12
Identity = 70/287 (24.39%), Postives = 123/287 (42.86%), Query Frame = 2

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTEL--KSISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIF-IKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLD-----------GTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L+++  L NW R    +I+++ S  ++ I+++   +  ++ + +N +++N+     D   TEL      F  H  + +   + +C + I+      +S    G++PISQE+LLL      ++  Y        K              +  ++   A+   +K+  + N G L  G T+EEA+        AC+ QV    C            S NA    LLD             + VV+ N    E++W  GE EFE+ +R L+   Y TGY ++
Sbjct:  137 QSRCKLASLYRLVDLFNWARFTSAYITVRVSKEQDHILISPRGLSFAEVTAANLVKVNIVGEVVDQGSTELGIDHFGFAPHAAIYSMRPDVRCIIHIHTPATTAVSSMKCGILPISQEALLLG-----DVSCYGYHGSLDNK--------------EEMVEFQKALGPTSKVMMLSNHGLLALGETVEEAFHYVYHSQLACEIQVHSLRC------------SGNADNLTLLDRQKFKPLTQGVAAAGVVIDN----EVKWKVGEAEFESLLRMLDNLGYRTGYAYR 388

[Close]

Query:   44 QLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTEL--KSISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIF-IKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLD-----------GTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            Q + KL  L+++  L NW R    +I+++ S  ++ I+++   +  ++ + +N +++N+     D   TEL      F  H  + +   + +C + I+      +S    G++PISQE+LLL      ++  Y        K              +  ++   A+   +K+  + N G L  G T+EEA+        AC+ QV    C            S NA    LLD             + VV+ N    E++W  GE EFE+ +R L+   Y TGY ++
Sbjct:  137 QSRCKLASLYRLVDLFNWARFTSAYITVRVSKEQDHILISPRGLSFAEVTAANLVKVNIVGEVVDQGSTELGIDHFGFAPHAAIYSMRPDVRCIIHIHTPATTAVSSMKCGILPISQEALLLG-----DVSCYGYHGSLDNK--------------EEMVEFQKALGPTSKVMMLSNHGLLALGETVEEAFHYVYHSQLACEIQVHSLRC------------SGNADNLTLLDRQKFKPLTQGVAAAGVVIDN----EVKWKVGEAEFESLLRMLDNLGYRTGYAYR 388

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Medaka
Match: add3a (gamma-adducin [Source:NCBI gene;Acc:101164133])

HSP 1 Score: 66.6254 bits (161), Expect = 6.287e-12
Identity = 70/276 (25.36%), Postives = 123/276 (44.57%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +I+ + S  ++ I++    +  ++ S SN +++N+     D   T L   S  F  H  + +   + +C + ++      +S    G++PISQE+L+L      +I +Y       T   S D+      L K       A+    K+ + +N G +  G T+EEA+       YAC+ QV    C       IV   E+ ++ +  +     ++   IN    + RW  GELEFE+ MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLVDLFGWAHFANSYITGRVSKEQDHILIIPRGLSFAEASASNLVKVNIIGDVIDQGSTSLSINSSGFSPHAAIYSMRPDIRCIIHVHTPAAAAVSSMKCGILPISQEALILG-----DIAYY-------TYHGSLDDQEERRELQK-------ALGPTAKVLVLRNHGVVALGETMEEAFHYIYNAQYACEIQVNAISCAGGVENLIVLDQEKYRSRVFAV-----ASAAAIN-MAGQYRWKIGELEFESLMRMLDNLGYRTGYTYR 388

[Close]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Medaka
Match: add3a (gamma-adducin [Source:NCBI gene;Acc:101164133])

HSP 1 Score: 66.2402 bits (160), Expect = 9.311e-12
Identity = 70/276 (25.36%), Postives = 123/276 (44.57%), Query Frame = 2

Query:   50 KSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIK-SDNSPSNFLELNL-----DNFPTELK--SISFLIHFLVQN-TVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKN--IVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFK 841
            + KL  L+++  L  W      +I+ + S  ++ I++    +  ++ S SN +++N+     D   T L   S  F  H  + +   + +C + ++      +S    G++PISQE+L+L      +I +Y       T   S D+      L K       A+    K+ + +N G +  G T+EEA+       YAC+ QV    C       IV   E+ ++ +  +     ++   IN    + RW  GELEFE+ MR L+   Y TGY ++
Sbjct:  138 RCKLASLYRLVDLFGWAHFANSYITGRVSKEQDHILIIPRGLSFAEASASNLVKVNIIGDVIDQGSTSLSINSSGFSPHAAIYSMRPDIRCIIHVHTPAAAAVSSMKCGILPISQEALILG-----DIAYY-------TYHGSLDDQEERRELQK-------ALGPTAKVLVLRNHGVVALGETMEEAFHYIYNAQYACEIQVNAISCAGGVENLIVLDQEKYRSRVFAV-----ASAAAIN-MAGQYRWKIGELEFESLMRMLDNLGYRTGYTYR 388

[Close]

BLAST of Aldolase_II domain-containing protein vs. Planmine SMEST
Match: SMESG000044944.1 (SMESG000044944.1)

HSP 1 Score: 552.362 bits (1422), Expect = 0.000e+0
Identity = 273/279 (97.85%), Postives = 275/279 (98.57%), Query Frame = 2

Query:   23 MSENSINQLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIKSDNSPSNFLELNLDNFPTELKSISFLIHFLVQNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFKLKNIWK 859
            M ENSINQLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIKSDN+PSNFL+LNLDNFPTEL SISFLIHFLVQNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYE  NEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFKLKNIWK
Sbjct:    1 MPENSINQLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNNPKIKSDNNPSNFLKLNLDNFPTELNSISFLIHFLVQNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYEFVNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFKLKNIWK 279

[Close]

BLAST of Aldolase_II domain-containing protein vs. Planmine SMEST
Match: SMESG000027670.1 (SMESG000027670.1)

HSP 1 Score: 115.161 bits (287), Expect = 4.126e-32
Identity = 50/105 (47.62%), Postives = 72/105 (68.57%), Query Frame = 2

Query:  545 VGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFKLKNIWK 859
            +G  VTG+TIEE WF   +  YAC+TQ+KL  CIHS+N++ P  E++  +      G S+ +++NN    + WL G+LEFEA MR LEY++  +GYDFK+K+IWK
Sbjct:    1 MGAFVTGKTIEETWFNCYIFDYACQTQMKLGKCIHSENVIVPGIEAQKNVLKQFKGGISSTLMLNNPNDNVEWLPGQLEFEALMRDLEYNESSSGYDFKIKSIWK 105

[Close]

BLAST of Aldolase_II domain-containing protein vs. Planmine SMEST
Match: SMESG000059133.1 (SMESG000059133.1)

HSP 1 Score: 67.781 bits (164), Expect = 1.750e-12
Identity = 67/275 (24.36%), Postives = 126/275 (45.82%), Query Frame = 2

Query:   47 LKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVN-NPKIKSDNSPSNFLELNLD----NFPTELKSISFLIHFLV-QNTVNCQCALLINHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWLAGELEFEATMRQLEYSDYITGYDFKLKNI 853
            L+ KL  ++++     W  G  +  S++ +   N  + N +  +  + + SN +++NL     N  + +   S+++H  + Q+    +C + +    VV +S    GLI I++E++ L +     +  YE  +       +S      + L   Q  +  A+     I ++N G L  G+T+EEAWF   L V+AC+TQV+L+  + S N+             +L +       I +Q         EL+FE+ MR L+ + + TGY ++   I
Sbjct:  135 LRCKLASVYRLIDFHGWASGMMLHASVRINRESNEFLTNCHGLMNHEITASNLVKVNLKGEVLNAHSRIDLASWVLHSSIHQSDPRFKCVIHVRTPAVVAVSCMRSGLIKINEEAVKLGN-----VPIYEWGS-------ASVNVGPGERLSVEQSTLTEAIGHRKCILVRNQGLLARGKTVEEAWFYAGLAVHACETQVRLASSVGSVNL-------------LLANEEEREPEIEDQTI-------ELQFESLMRTLDAAGHRTGYLYRHAPI 377

[Close]

BLAST of Aldolase_II domain-containing protein vs. Planmine SMEST
Match: SMESG000012838.1 (SMESG000012838.1)

HSP 1 Score: 67.781 bits (164), Expect = 2.223e-12
Identity = 61/221 (27.60%), Postives = 112/221 (50.68%), Query Frame = 2

Query:  233 ELKSISFLIHFLVQNTVNCQCALL-INHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAI----KTILLDGTSNVVL--INNQKSE----LRWLAGELEFEATMRQLEYSDYITGYDFKLKNIWK 859
            E   ++++IH  + +  +   A+L +     + IS    GL+PI +E++LL S  I++             F  S+  SI  ++      + + ++ N+KI I  N G L+ G  IEEAW   M    AC+TQ+KL + +   ++  P +  +  +    ++  L G + + +  ++ + SE     +W  GELEFEA MR ++ + Y TGY ++ +NI++
Sbjct:  201 EANPLAWMIHSAIYSCQHSIRAILELKTPAALAISSLEHGLLPICREAILLGSTVILD---------NLPGF-VSESKSISLIMTDLNNYLTSVIVPNSKILIVPNCGFLICGEHIEEAWHLLMNCQIACETQMKLGN-LTIDDLYIPDKNCQADLFHQWRSTDLGGVTKIEIDSVSYENSEHVPQAQWRIGELEFEALMRHMDNNGYRTGYMYRQENIYQ 410

[Close]

BLAST of Aldolase_II domain-containing protein vs. Planmine SMEST
Match: SMESG000012838.1 (SMESG000012838.1)

HSP 1 Score: 67.3958 bits (163), Expect = 2.326e-12
Identity = 61/221 (27.60%), Postives = 112/221 (50.68%), Query Frame = 2

Query:  233 ELKSISFLIHFLVQNTVNCQCALL-INHTDVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDSIFDLLMKYQIKVNAAMLKNNKIFI-KNVGCLVTGRTIEEAWFEGMLVVYACKTQVKLSHCIHSKNIVFPSEESKNAI----KTILLDGTSNVVL--INNQKSE----LRWLAGELEFEATMRQLEYSDYITGYDFKLKNIWK 859
            E   ++++IH  + +  +   A+L +     + IS    GL+PI +E++LL S  I++             F  S+  SI  ++      + + ++ N+KI I  N G L+ G  IEEAW   M    AC+TQ+KL + +   ++  P +  +  +    ++  L G + + +  ++ + SE     +W  GELEFEA MR ++ + Y TGY ++ +NI++
Sbjct:  201 EANPLAWMIHSAIYSCQHSIRAILELKTPAALAISSLEHGLLPICREAILLGSTVILD---------NLPGF-VSESKSISLIMTDLNNYLTSVIVPNSKILIVPNCGFLICGEHIEEAWHLLMNCQIACETQMKLGN-LTIDDLYIPDKNCQADLFHQWRSTDLGGVTKIEIDSVSYENSEHVPQAQWRIGELEFEALMRHMDNNGYRTGYMYRQENIYQ 410

The following BLAST results are available for this feature:

BLAST of Aldolase_II domain-containing protein vs. Ensembl Human
BLAST of Aldolase_II domain-containing protein vs. Ensembl Celegans
BLAST of Aldolase_II domain-containing protein vs. Ensembl Fly
BLAST of Aldolase_II domain-containing protein vs. Ensembl Zebrafish
BLAST of Aldolase_II domain-containing protein vs. Ensembl Xenopus
BLAST of Aldolase_II domain-containing protein vs. Ensembl Mouse
BLAST of Aldolase_II domain-containing protein vs. UniProt/SwissProt
BLAST of Aldolase_II domain-containing protein vs. TrEMBL
BLAST of Aldolase_II domain-containing protein vs. Ensembl Cavefish
BLAST of Aldolase_II domain-containing protein vs. Ensembl Sea Lamprey
BLAST of Aldolase_II domain-containing protein vs. Ensembl Yeast
BLAST of Aldolase_II domain-containing protein vs. Ensembl Nematostella
BLAST of Aldolase_II domain-containing protein vs. Ensembl Medaka
BLAST of Aldolase_II domain-containing protein vs. Planmine SMEST

BLAST of Aldolase_II domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ADD3	1.568e-13	26.45	adducin 3 [Source:HGNC Symbol;Acc:HGNC:245]	[more]
ADD3	1.568e-13	26.45	adducin 3 [Source:HGNC Symbol;Acc:HGNC:245]	[more]
ADD3	2.534e-13	26.45	adducin 3 [Source:HGNC Symbol;Acc:HGNC:245]	[more]
ADD1	1.179e-8	24.73	adducin 1 [Source:HGNC Symbol;Acc:HGNC:243]	[more]
ADD1	1.211e-8	24.73	adducin 1 [Source:HGNC Symbol;Acc:HGNC:243]	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
add-2	3.495e-22	24.54	Adducin-related protein 2 [Source:UniProtKB/Swiss...	[more]
add-2	1.095e-20	24.54	Adducin-related protein 2 [Source:UniProtKB/Swiss...	[more]
add-2	1.095e-20	24.54	Adducin-related protein 2 [Source:UniProtKB/Swiss...	[more]
add-2	1.095e-20	24.54	Adducin-related protein 2 [Source:UniProtKB/Swiss...	[more]
add-1	8.954e-13	24.73	Adducin-related protein 1 [Source:UniProtKB/Swiss...	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hts	7.691e-13	24.92	gene:FBgn0263391 transcript:FBtr0309105	[more]
hts	7.691e-13	24.92	gene:FBgn0263391 transcript:FBtr0309103	[more]
hts	7.691e-13	24.92	gene:FBgn0263391 transcript:FBtr0309107	[more]
hts	1.417e-12	25.00	gene:FBgn0263391 transcript:FBtr0309102	[more]
hts	1.584e-12	28.13	gene:FBgn0263391 transcript:FBtr0309115	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
add3a	9.685e-15	25.54	adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-0301...	[more]
add3a	9.685e-15	25.54	adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-0301...	[more]
add3a	1.265e-14	25.54	adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-0301...	[more]
add3a	1.351e-14	25.54	adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-0301...	[more]
add3a	1.351e-14	25.54	adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-0301...	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
atr	2.822e-13	24.00	ATR serine/threonine kinase [Source:Xenbase;Acc:XB...	[more]
atr	3.916e-13	23.91	ATR serine/threonine kinase [Source:Xenbase;Acc:XB...	[more]
atr	4.115e-13	23.91	ATR serine/threonine kinase [Source:Xenbase;Acc:XB...	[more]
atr	4.634e-13	23.91	ATR serine/threonine kinase [Source:Xenbase;Acc:XB...	[more]
atr	5.045e-13	23.91	ATR serine/threonine kinase [Source:Xenbase;Acc:XB...	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Add3	1.529e-13	25.00	adducin 3 (gamma) [Source:MGI Symbol;Acc:MGI:13516...	[more]
Add3	1.529e-13	25.00	adducin 3 (gamma) [Source:MGI Symbol;Acc:MGI:13516...	[more]
Add3	1.529e-13	25.00	adducin 3 (gamma) [Source:MGI Symbol;Acc:MGI:13516...	[more]
Add3	1.529e-13	25.00	adducin 3 (gamma) [Source:MGI Symbol;Acc:MGI:13516...	[more]
Add3	1.529e-13	25.00	adducin 3 (gamma) [Source:MGI Symbol;Acc:MGI:13516...	[more]

BLAST of Aldolase_II domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q20952\|ADD2_CAEEL	1.393e-19	24.54	Adducin-related protein 2 OS=Caenorhabditis elegan...	[more]
sp\|Q9UEY8\|ADDG_HUMAN	1.217e-12	26.45	Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1...	[more]
sp\|Q9QYB5\|ADDG_MOUSE	1.437e-12	25.00	Gamma-adducin OS=Mus musculus OX=10090 GN=Add3 PE=...	[more]
sp\|Q9U9K0\|ADD1_CAEEL	1.470e-11	24.73	Adducin-related protein 1 OS=Caenorhabditis elegan...	[more]
sp\|Q02645\|HTS_DROME	1.903e-11	25.17	Protein hu-li tai shao OS=Drosophila melanogaster ...	[more]

BLAST of Aldolase_II domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q1ZXU2	1.318e-18	24.54	Aldolase_II domain-containing protein OS=Caenorhab...	[more]
A0A1I7TP00	2.182e-18	25.00	Aldolase_II domain-containing protein OS=Caenorhab...	[more]
A0A2G5TGG3	4.292e-17	24.00	Aldolase_II domain-containing protein OS=Caenorhab...	[more]
A8Y444	5.220e-17	23.64	Protein CBR-ADD-2 OS=Caenorhabditis briggsae OX=62...	[more]
A0A2H2IJW5	1.338e-16	23.99	Aldolase_II domain-containing protein OS=Caenorhab...	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
add3a	9.379e-11	24.46	adducin 3 (gamma) a [Source:ZFIN;Acc:ZDB-GENE-0301...	[more]
add1	1.047e-10	25.18	adducin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-030909...	[more]
add3b	1.364e-10	23.47	gamma-adducin-like [Source:NCBI gene;Acc:103046517...	[more]
add1	2.204e-10	25.18	adducin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-030909...	[more]
add1	2.279e-10	25.18	adducin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-030909...	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
add1	6.895e-11	24.73	adducin 1 (alpha) [Source:ZFIN;Acc:ZDB-GENE-030909...	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Aldolase_II domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO42734	2.848e-10	23.95	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42733	8.728e-7	23.53	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Aldolase_II domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
add3b	2.081e-12	24.83	gamma-adducin [Source:NCBI gene;Acc:101170613]	[more]
add3b	2.278e-12	24.39	gamma-adducin [Source:NCBI gene;Acc:101170613]	[more]
add3b	2.278e-12	24.39	gamma-adducin [Source:NCBI gene;Acc:101170613]	[more]
add3a	6.287e-12	25.36	gamma-adducin [Source:NCBI gene;Acc:101164133]	[more]
add3a	9.311e-12	25.36	gamma-adducin [Source:NCBI gene;Acc:101164133]	[more]

BLAST of Aldolase_II domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000044944.1	0.000e+0	97.85	SMESG000044944.1	[more]
SMESG000027670.1	4.126e-32	47.62	SMESG000027670.1	[more]
SMESG000059133.1	1.750e-12	24.36	SMESG000059133.1	[more]
SMESG000012838.1	2.223e-12	27.60	SMESG000012838.1	[more]
SMESG000012838.1	2.326e-12	27.60	SMESG000012838.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30014826 ID=SMED30014826|Name=Aldolase_II domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=879bp
TTTTATATAAAATTGAATGGTTATGTCTGAAAATTCAATAAATCAATTGA
AATCTAAGTTATGTTGTTTGCATAAAATTGGAAGCCTCGATAATTGGTTT
AGGGGCGAAGAAATTTTCATAAGTATTAAACATTCTATTGCAAAAAATTT
TATAATTGTAAACAACCCAAAAATAAAGTCTGATAACAGTCCTTCTAACT
TTTTGGAATTAAATTTGGATAATTTTCCAACTGAATTAAAATCAATTTCT
TTCTTAATCCATTTTCTCGTACAAAATACAGTTAATTGCCAATGCGCTCT
ATTAATAAATCATACCGATGTCGTTAAGATATCACAAAATGGAATCGGTT
TAATTCCAATCAGTCAAGAATCGTTGCTGTTAAAGAGTCATGAAATTGTT
GAAATTGAATTTTATGAACTTTTCAATGAATTCTTCACAAAATTCAATTC
ATCAGATGAGGATTCTATTTTTGATTTACTTATGAAATATCAAATTAAAG
TTAATGCAGCCATGTTAAAAAATAATAAAATTTTTATAAAAAATGTTGGA
TGCTTAGTGACTGGGAGAACAATTGAGGAGGCATGGTTCGAGGGAATGCT
GGTGGTGTATGCGTGCAAAACCCAGGTAAAACTTTCGCATTGTATTCATT
CGAAAAATATTGTCTTTCCAAGCGAGGAATCCAAAAATGCAATTAAAACA
ATTCTACTTGATGGGACTTCTAATGTAGTGTTGATAAATAATCAGAAATC
GGAACTCAGGTGGTTGGCTGGGGAATTGGAATTCGAGGCCACAATGAGAC
AGCTTGAATATTCGGATTACATAACCGGATACGATTTCAAATTGAAAAAT
ATCTGGAAATAAAAGATTTCTTTTGTGGT

protein sequence of SMED30014826-orf-1

>SMED30014826-orf-1 ID=SMED30014826-orf-1|Name=SMED30014826-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=282bp
MVMSENSINQLKSKLCCLHKIGSLDNWFRGEEIFISIKHSIAKNFIIVNN
PKIKSDNSPSNFLELNLDNFPTELKSISFLIHFLVQNTVNCQCALLINHT
DVVKISQNGIGLIPISQESLLLKSHEIVEIEFYELFNEFFTKFNSSDEDS
IFDLLMKYQIKVNAAMLKNNKIFIKNVGCLVTGRTIEEAWFEGMLVVYAC
KTQVKLSHCIHSKNIVFPSEESKNAIKTILLDGTSNVVLINNQKSELRWL
AGELEFEATMRQLEYSDYITGYDFKLKNIWK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036409	Aldolase_II/adducin_N_sf
IPR001303	Aldolase_II/adducin_N

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm
GO:0005811	lipid particle
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016328	lateral plasma membrane
GO:0035183	female germline ring canal inner rim
GO:0045169	fusome
GO:0045170	spectrosome
GO:0045172	germline ring canal

Vocabulary: **biological process**
Term	Definition
GO:0007275	multicellular organism development
GO:0007282	cystoblast division
GO:0007294	germarium-derived oocyte fate determination
GO:0007411	axon guidance
GO:0007527	adult somatic muscle development
GO:0008302	female germline ring canal formation, actin assembly
GO:0030154	cell differentiation
GO:0030723	ovarian fusome organization
GO:0030724	testicular fusome organization
GO:0031987	locomotion involved in locomotory behavior
GO:0045214	sarcomere organization
GO:0045478	fusome organization
GO:0048134	germ-line cyst formation
GO:0048135	female germ-line cyst formation
GO:0048477	oogenesis
GO:0051297	centrosome organization
GO:0061572	actin filament bundle organization
GO:0070050	neuron cellular homeostasis
GO:0072499	photoreceptor cell axon guidance
GO:0000212	meiotic spindle organization

Vocabulary: **molecular function**
Term	Definition
GO:0003779	actin binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR036409	Class II aldolase/adducin N-terminal domain superfamily	GENE3D	G3DSA:3.40.225.10		coord: 4..268 e-value: 1.4E-17 score: 65.6
IPR036409	Class II aldolase/adducin N-terminal domain superfamily	SUPERFAMILY	SSF53639	AraD/HMP-PK domain-like	coord: 8..205
IPR001303	Class II aldolase/adducin N-terminal	PFAM	PF00596	Aldolase_II	coord: 34..203 e-value: 1.4E-5 score: 25.1
None	No IPR available	PANTHER	PTHR10672	ADDUCIN	coord: 9..274

Main menu

Aldolase_II domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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