slc11a-1

Overview
Nameslc11a-1 (AKN21474.1)
Smed IDSMED30014808
Length (bp)1885
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of slc11a-1 (SMED30014808) t-SNE clustered cells

Violin plots show distribution of expression levels for slc11a-1 (SMED30014808) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc11a-1 (SMED30014808) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc11a-1 (SMED30014808) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014808

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30014808h1SMcG0003967 Contig3248GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014808h1SMcG0003967 Contig6204newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30014808h1SMcG0003967 dd_Smed_v4_4739_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30014808h1SMcG0003967 Contig25723newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of slc11a-1 vs. Ensembl Human
Match: SLC11A2 (solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908])

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 305/461 (66.16%), Postives = 378/461 (82.00%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E+++IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLATL+GL++QRLAARLGVVTG HLAEVC+++YPK+PR+ILW+M+E+AIIGSDMQEVIG+AIA NLLS G IPLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ VKP+Q++VLKGMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NRN + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+GK    +VE C     PH  +F   ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M++F NG   RI+  + V + C+   IN+YFV+V+++
Sbjct:   77 ATYFNEKISIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICS---INMYFVVVYVR 529
[Close]
BLAST of slc11a-1 vs. Ensembl Human
Match: SLC11A2 (solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908])

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 305/461 (66.16%), Postives = 378/461 (82.00%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E+++IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLATL+GL++QRLAARLGVVTG HLAEVC+++YPK+PR+ILW+M+E+AIIGSDMQEVIG+AIA NLLS G IPLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ VKP+Q++VLKGMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NRN + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+GK    +VE C     PH  +F   ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M++F NG   RI+  + V + C+   IN+YFV+V+++
Sbjct:   77 ATYFNEKISIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICS---INMYFVVVYVR 529
[Close]
BLAST of slc11a-1 vs. Ensembl Human
Match: SLC11A2 (solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908])

HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0
Identity = 305/461 (66.16%), Postives = 378/461 (82.00%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E+++IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLATL+GL++QRLAARLGVVTG HLAEVC+++YPK+PR+ILW+M+E+AIIGSDMQEVIG+AIA NLLS G IPLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ VKP+Q++VLKGMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NRN + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+GK    +VE C     PH  +F   ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M++F NG   RI+  + V + C+   IN+YFV+V+++
Sbjct:   48 ATYFNEKISIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICS---INMYFVVVYVR 500
[Close]
BLAST of slc11a-1 vs. Ensembl Human
Match: SLC11A2 (solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908])

HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0
Identity = 305/461 (66.16%), Postives = 378/461 (82.00%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E+++IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLATL+GL++QRLAARLGVVTG HLAEVC+++YPK+PR+ILW+M+E+AIIGSDMQEVIG+AIA NLLS G IPLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ VKP+Q++VLKGMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NRN + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+GK    +VE C     PH  +F   ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M++F NG   RI+  + V + C+   IN+YFV+V+++
Sbjct:   48 ATYFNEKISIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICS---INMYFVVVYVR 500
[Close]
BLAST of slc11a-1 vs. Ensembl Human
Match: SLC11A2 (solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908])

HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0
Identity = 305/461 (66.16%), Postives = 378/461 (82.00%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E+++IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLATL+GL++QRLAARLGVVTG HLAEVC+++YPK+PR+ILW+M+E+AIIGSDMQEVIG+AIA NLLS G IPLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ VKP+Q++VLKGMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NRN + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+GK    +VE C     PH  +F   ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M++F NG   RI+  + V + C+   IN+YFV+V+++
Sbjct:   44 ATYFNEKISIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICS---INMYFVVVYVR 496
[Close]
BLAST of slc11a-1 vs. Ensembl Celegans
Match: smf-1 (NRAMP-like transporter smf-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21434])

HSP 1 Score: 534.643 bits (1376), Expect = 0.000e+0
Identity = 276/489 (56.44%), Postives = 372/489 (76.07%), Query Frame = 2 
Query:  161 QERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKA-NKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFY-QGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWVXXXXXXXXXXXXXXXXVYLCLYGLV 1621
            QERV+IP DD        FSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGA A +KLLW+LL A ++G+++QR++ARLGVV+G H+AEV YQ YP++PRIILW+MIEIAI+ SDMQEVIGTAIA  LLS G +PL+ GV +TI+DTFTFL +D+YG+RKLE  F  LI TM  +FGY+++VVKP   EV+ GM VP+C  CG  E +QA+ ++GAVIMPHN+YLHSALVKSR ++R  R ++ EAN Y+ +ES +ALF+SF IN+FVV+VFA G Y K    + E C A + IP  ++F ++    ++DIYKGGI+LGC+FG   ++IW IGI AAGQSSTMTGTY GQF MEGF+ + W +W+RVL+TR+IAI PT+ + FY QG+ NLT MND LN +  +QLPFA+IPI+TFTSS+++M +F++ ++  +  +  +  ++ IN+YF+  ++ + + + W   ++++     Y+LF++YL LY LV
Sbjct:   37 QERVDIPVDDV----EKAFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAQAAYKLLWVLLSAHIIGMLLQRMSARLGVVSGKHMAEVAYQFYPRLPRIILWLMIEIAIVCSDMQEVIGTAIAIFLLSKGFVPLYVGVFITILDTFTFLLIDRYGIRKLELIFGFLILTMTVSFGYEFVVVKPPIGEVISGMVVPWCAGCGKGEFMQAISVVGAVIMPHNLYLHSALVKSRRVDRKDRRRVAEANKYFTLESAIALFLSFFINLFVVAVFAHGLYQKTNADVREMCIARHDIPDADIFPNNTEPVEVDIYKGGIYLGCQFGAIAMFIWGIGIFAAGQSSTMTGTYTGQFVMEGFVKIEWPKWKRVLITRAIAITPTLVLTFYSQGVQNLTGMNDFLNCVQMIQLPFALIPIITFTSSRKIMHDFRSSKVFQIFALITSALILSINVYFISDYVFSRLGSEWYIIMVLAPITFAYVLFVLYLALYCLV 521
[Close]
BLAST of slc11a-1 vs. Ensembl Celegans
Match: smf-2 (NRAMP-like transporter smf-2 [Source:UniProtKB/Swiss-Prot;Acc:Q21433])

HSP 1 Score: 495.738 bits (1275), Expect = 5.681e-170
Identity = 268/486 (55.14%), Postives = 363/486 (74.69%), Query Frame = 2 
Query:  170 VNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEEC-KANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFY-QGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWVXXXXXXXXXXXXXXXXVYLCLYGLV 1621
            V IP+D++     + FS++KLWAFTGPGFLMSIAYLDPGNIESDLQ+GA A++KLLW+LL++ ++G+++QR++ARLGVV+G H+AE+ Y  YP +PRIILW+MIEIAI+ SDMQEVIGTAIA  LLS+G IPL  GV++TI+DTFTFLF+D+YG+RKLE  F  LI+TM  +FGY+++V+KP   +VL G  VP+C  CG +E++ A+ I GAVIMPHN YLHSALVKSR ++R+ + +I EAN Y+ IES  AL +SF IN+FV+SVFA G Y K    +   C   N IP   VF ++ +   +D+++GGI+LGC+FGL  + IWAIGI AAGQSSTMTGTY GQF MEGF+ ++W +W+RVL+TR++AI PT+ +     GI NLT MND LN +  +QLPFA+IP++TFTSSKR+M  F+  +     ++      IGIN+YF+  ++  N    W+ +++I  F  LY+ FI+YL +Y LV
Sbjct:   27 VKIPEDEK----NTWFSWRKLWAFTGPGFLMSIAYLDPGNIESDLQAGAQAEYKLLWVLLVSHIVGMLLQRMSARLGVVSGKHMAEIAYDYYPLVPRIILWLMIEIAIVCSDMQEVIGTAIAIYLLSSGKIPLLVGVLITILDTFTFLFIDRYGIRKLEFIFVALISTMAISFGYEFVVMKPVLTKVLTGTVVPWCSGCGKEEIITAISIFGAVIMPHNFYLHSALVKSRKVDRSSKTRIAEANKYFSIESAFALSVSFFINLFVLSVFARGLYQKTNGDVNSMCLSHNDIPDSNVFPNNTSSVTVDLFQGGIYLGCQFGLFAMIIWAIGIFAAGQSSTMTGTYTGQFVMEGFVRISWPKWKRVLITRAVAITPTLILCIKAHGIKNLTGMNDFLNCVQMVQLPFALIPMITFTSSKRIMHNFRTSKPLQYFSIICGIITIGINVYFIFQYVTENFGTGWLIFVIIGPFTLLYIAFILYLAIYCLV 508
[Close]
BLAST of slc11a-1 vs. Ensembl Celegans
Match: smf-3 (NRAMP-like transporter smf-3 [Source:UniProtKB/Swiss-Prot;Acc:Q95XG8])

HSP 1 Score: 479.945 bits (1234), Expect = 1.524e-163
Identity = 261/460 (56.74%), Postives = 345/460 (75.00%), Query Frame = 2 
Query:  161 QERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEEC---KANKIPHW---EVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIA-FYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFI 1519
            Q+   +  + E   D + FS++KLWAFTGPGFLMSIAYLDPGNIESDLQ+GAI+ FKL+W+LL+A ++GL++QRLAARLGVV+G H+AE+ +  YPKIPR++LW+++E AI+GSDMQEVIGTAI+F LLSNGVIPLW GV++TI DTFTFLFL+KYG+RK EAFF  LIT M   FGY++ V  P+  ++  GMFVP+C  C +  ++Q V IIGAVIMPHN YLHSALVKSR ++R    K+ EAN Y+ IES  ALF+SF+IN  V+SVFA+G YGK    I + C     N +P +   E   ++DA    DIY  GIFLGC FG+  LY+WA+GILAAGQSSTMTGTYAGQFAMEGF+ +   +W+R+L+TRS+AI PT+ +  F  GI N++ +ND LN L  +QLPFA+IP+LTF S + +M E+K   +S ++++ ++  ++ IN YF+  +I
Sbjct:   22 QQTYEVQVEVEDTPDTT-FSWRKLWAFTGPGFLMSIAYLDPGNIESDLQAGAISYFKLIWVLLVAHIMGLLLQRLAARLGVVSGKHMAEIAFSYYPKIPRLVLWMLVESAIVGSDMQEVIGTAISFYLLSNGVIPLWAGVLITICDTFTFLFLEKYGVRKFEAFFCFLITCMAITFGYEFGVSAPDAGKMFSGMFVPWCNGCDNNMVMQGVAIIGAVIMPHNFYLHSALVKSRRVDRRRAEKVTEANKYFFIESAFALFVSFIINTLVISVFAQGMYGKTNQDIRDTCYNNTHNGMPDFYKVEFPANNDAAQS-DIYHAGIFLGCTFGIFALYVWAVGILAAGQSSTMTGTYAGQFAMEGFIQIKLPQWKRILITRSLAILPTLAVVIFSGGIDNISSLNDFLNCLQLIQLPFALIPVLTFVSDRNIMHEYKLASVSKVVSIVISLIILFINFYFLYSWI 479
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BLAST of slc11a-1 vs. Ensembl Fly
Match: Mvl (gene:FBgn0011672 transcript:FBtr0306350)

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 300/466 (64.38%), Postives = 364/466 (78.11%), Query Frame = 2 
Query:  143 AASTYF-QERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSD-----ALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQ 1522
            A   YF  E+V IPDDD        FSF+KLWAFTGPGFLMSIAYLDPGNIESD+QSGA A++K+LW+LL AT+LGL+MQRLAARLGVVTG HLAE+CY++Y ++PR ILW+MIEIAIIGSDMQEVIGTAIA  LLSN V+PLWGGV++TI+DTFTFLFLDKYGLRKLE  F  LIT M  +FGY+YIV  PNQ EVL+GMFVP+C NC S  LLQAVG++GAVIMPHN+YLHSALVKSR+I+R    K+ EANFY+ IE+ VALF+SF+IN+FVV+VFA G YGK    +VE CK   +      +  D     A+ D D+YKGG+FLGC FG   +YIW +GILAAGQSSTMTGTYAGQF+MEGFLNL W RW RVL+TR IAI PT  +A +  + +LT MND+LN +MS+QLPFA IP + FTS   +M EF NG  + ++++ L   VIG+N+YFV+V ++
Sbjct:   50 AKQAYFSDEKVLIPDDDS---TNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVE 512
[Close]
BLAST of slc11a-1 vs. Ensembl Fly
Match: Mvl (gene:FBgn0011672 transcript:FBtr0306351)

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 300/466 (64.38%), Postives = 364/466 (78.11%), Query Frame = 2 
Query:  143 AASTYF-QERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSD-----ALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQ 1522
            A   YF  E+V IPDDD        FSF+KLWAFTGPGFLMSIAYLDPGNIESD+QSGA A++K+LW+LL AT+LGL+MQRLAARLGVVTG HLAE+CY++Y ++PR ILW+MIEIAIIGSDMQEVIGTAIA  LLSN V+PLWGGV++TI+DTFTFLFLDKYGLRKLE  F  LIT M  +FGY+YIV  PNQ EVL+GMFVP+C NC S  LLQAVG++GAVIMPHN+YLHSALVKSR+I+R    K+ EANFY+ IE+ VALF+SF+IN+FVV+VFA G YGK    +VE CK   +      +  D     A+ D D+YKGG+FLGC FG   +YIW +GILAAGQSSTMTGTYAGQF+MEGFLNL W RW RVL+TR IAI PT  +A +  + +LT MND+LN +MS+QLPFA IP + FTS   +M EF NG  + ++++ L   VIG+N+YFV+V ++
Sbjct:   50 AKQAYFSDEKVLIPDDDS---TNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVE 512
[Close]
BLAST of slc11a-1 vs. Ensembl Fly
Match: Mvl (gene:FBgn0011672 transcript:FBtr0301477)

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 300/466 (64.38%), Postives = 364/466 (78.11%), Query Frame = 2 
Query:  143 AASTYF-QERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSD-----ALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQ 1522
            A   YF  E+V IPDDD        FSF+KLWAFTGPGFLMSIAYLDPGNIESD+QSGA A++K+LW+LL AT+LGL+MQRLAARLGVVTG HLAE+CY++Y ++PR ILW+MIEIAIIGSDMQEVIGTAIA  LLSN V+PLWGGV++TI+DTFTFLFLDKYGLRKLE  F  LIT M  +FGY+YIV  PNQ EVL+GMFVP+C NC S  LLQAVG++GAVIMPHN+YLHSALVKSR+I+R    K+ EANFY+ IE+ VALF+SF+IN+FVV+VFA G YGK    +VE CK   +      +  D     A+ D D+YKGG+FLGC FG   +YIW +GILAAGQSSTMTGTYAGQF+MEGFLNL W RW RVL+TR IAI PT  +A +  + +LT MND+LN +MS+QLPFA IP + FTS   +M EF NG  + ++++ L   VIG+N+YFV+V ++
Sbjct:   50 AKQAYFSDEKVLIPDDDS---TNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVE 512
[Close]
BLAST of slc11a-1 vs. Ensembl Fly
Match: Mvl (gene:FBgn0011672 transcript:FBtr0089521)

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 300/466 (64.38%), Postives = 364/466 (78.11%), Query Frame = 2 
Query:  143 AASTYF-QERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSD-----ALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQ 1522
            A   YF  E+V IPDDD        FSF+KLWAFTGPGFLMSIAYLDPGNIESD+QSGA A++K+LW+LL AT+LGL+MQRLAARLGVVTG HLAE+CY++Y ++PR ILW+MIEIAIIGSDMQEVIGTAIA  LLSN V+PLWGGV++TI+DTFTFLFLDKYGLRKLE  F  LIT M  +FGY+YIV  PNQ EVL+GMFVP+C NC S  LLQAVG++GAVIMPHN+YLHSALVKSR+I+R    K+ EANFY+ IE+ VALF+SF+IN+FVV+VFA G YGK    +VE CK   +      +  D     A+ D D+YKGG+FLGC FG   +YIW +GILAAGQSSTMTGTYAGQF+MEGFLNL W RW RVL+TR IAI PT  +A +  + +LT MND+LN +MS+QLPFA IP + FTS   +M EF NG  + ++++ L   VIG+N+YFV+V ++
Sbjct:   50 AKQAYFSDEKVLIPDDDS---TNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVE 512
[Close]
BLAST of slc11a-1 vs. Ensembl Fly
Match: Mvl (gene:FBgn0011672 transcript:FBtr0301478)

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 300/466 (64.38%), Postives = 364/466 (78.11%), Query Frame = 2 
Query:  143 AASTYF-QERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSD-----ALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQ 1522
            A   YF  E+V IPDDD        FSF+KLWAFTGPGFLMSIAYLDPGNIESD+QSGA A++K+LW+LL AT+LGL+MQRLAARLGVVTG HLAE+CY++Y ++PR ILW+MIEIAIIGSDMQEVIGTAIA  LLSN V+PLWGGV++TI+DTFTFLFLDKYGLRKLE  F  LIT M  +FGY+YIV  PNQ EVL+GMFVP+C NC S  LLQAVG++GAVIMPHN+YLHSALVKSR+I+R    K+ EANFY+ IE+ VALF+SF+IN+FVV+VFA G YGK    +VE CK   +      +  D     A+ D D+YKGG+FLGC FG   +YIW +GILAAGQSSTMTGTYAGQF+MEGFLNL W RW RVL+TR IAI PT  +A +  + +LT MND+LN +MS+QLPFA IP + FTS   +M EF NG  + ++++ L   VIG+N+YFV+V ++
Sbjct:   50 AKQAYFSDEKVLIPDDDS---TNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVE 512
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BLAST of slc11a-1 vs. Ensembl Zebrafish
Match: slc11a2 (solute carrier family 11 member 2 [Source:ZFIN;Acc:ZDB-GENE-021115-1])

HSP 1 Score: 207.223 bits (526), Expect = 2.121e-62
Identity = 101/171 (59.06%), Postives = 127/171 (74.27%), Query Frame = 2 
Query: 1016 EECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFI 1519
            ++C     PH ++F +++   ++DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RVLLTRSIAI PT+ +A +Q + +LT MND LNVL SMQLPFA+IPILTFTS   +M +F NG   +I   L + L C    IN+YFVIV++
Sbjct:    3 QQCNETGSPHTDLFPANNETLEVDIYKGGVVLGCFFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIFPTLLVAVFQDVQHLTGMNDFLNVLQSMQLPFALIPILTFTSLTSLMHDFANGLVWKIGGGLLILLVC---AINMYFVIVYV 170
[Close]
BLAST of slc11a-1 vs. Ensembl Xenopus
Match: SLC11A1 (solute carrier family 11 member 1 [Source:NCBI gene;Acc:100498626])

HSP 1 Score: 583.563 bits (1503), Expect = 0.000e+0
Identity = 300/463 (64.79%), Postives = 365/463 (78.83%), Query Frame = 2 
Query:  131 SNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFI 1519
            +   +  TY  ER+ +P+          FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQ GAIA FKLLW+LL AT+LGL+ QRLA RLGVVTG  LA++C   YPK PR ILW+++EIAIIGSDMQEVIGTAIAF+LLS+G IPLWGGV++TIIDT  FLFLDKYGLRKLEAFFA+LIT M   FGY+Y+VVKP+Q EVLKGMF PYC  CGS ELLQAVGIIGA+IMPHNIYLHS+LVKSR ++R  + ++ EAN YY+IES +ALF+SFLIN+FV++VFAE FY K      + C+ +  PH +VF S++    +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTYAGQF MEGFLNL W R+ RVL TRS AI PT+F+A ++ + +LT MNDLLNVL S+ LPFA++P+LTFTS + +M +F NG I  ++ + L   ++ IN+YFV V+I
Sbjct:   26 TKEESERTYLDERIAVPNTGS-----PGFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQCGAIAGFKLLWVLLGATVLGLLCQRLAVRLGVVTGMDLAQICRYYYPKAPRWILWILVEIAIIGSDMQEVIGTAIAFSLLSSGRIPLWGGVLITIIDTLFFLFLDKYGLRKLEAFFALLITIMAVTFGYEYVVVKPDQREVLKGMFYPYCSGCGSPELLQAVGIIGAIIMPHNIYLHSSLVKSRVVDRKQKQEVSEANMYYMIESSIALFVSFLINLFVMAVFAEAFYNKTNQDAYDVCQNSSSPHADVFPSNNDSLSVDIYKGGVILGCFFGPAALYIWAVGILAAGQSSTMTGTYAGQFVMEGFLNLKWSRFYRVLFTRSCAIIPTVFVAAFKDVEHLTGMNDLLNVLQSILLPFALLPVLTFTSMRPLMCDFVNGLIGKIVAILLIALIMAINLYFVFVYI 483
[Close]
BLAST of slc11a-1 vs. Ensembl Xenopus
Match: SLC11A1 (solute carrier family 11 member 1 [Source:NCBI gene;Acc:100498626])

HSP 1 Score: 582.022 bits (1499), Expect = 0.000e+0
Identity = 300/463 (64.79%), Postives = 365/463 (78.83%), Query Frame = 2 
Query:  131 SNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFI 1519
            +   +  TY  ER+ +P+          FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQ GAIA FKLLW+LL AT+LGL+ QRLA RLGVVTG  LA++C   YPK PR ILW+++EIAIIGSDMQEVIGTAIAF+LLS+G IPLWGGV++TIIDT  FLFLDKYGLRKLEAFFA+LIT M   FGY+Y+VVKP+Q EVLKGMF PYC  CGS ELLQAVGIIGA+IMPHNIYLHS+LVKSR ++R  + ++ EAN YY+IES +ALF+SFLIN+FV++VFAE FY K      + C+ +  PH +VF S++    +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTYAGQF MEGFLNL W R+ RVL TRS AI PT+F+A ++ + +LT MNDLLNVL S+ LPFA++P+LTFTS + +M +F NG I  ++ + L   ++ IN+YFV V+I
Sbjct:   41 TKEESERTYLDERIAVPNTGS-----PGFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQCGAIAGFKLLWVLLGATVLGLLCQRLAVRLGVVTGMDLAQICRYYYPKAPRWILWILVEIAIIGSDMQEVIGTAIAFSLLSSGRIPLWGGVLITIIDTLFFLFLDKYGLRKLEAFFALLITIMAVTFGYEYVVVKPDQREVLKGMFYPYCSGCGSPELLQAVGIIGAIIMPHNIYLHSSLVKSRVVDRKQKQEVSEANMYYMIESSIALFVSFLINLFVMAVFAEAFYNKTNQDAYDVCQNSSSPHADVFPSNNDSLSVDIYKGGVILGCFFGPAALYIWAVGILAAGQSSTMTGTYAGQFVMEGFLNLKWSRFYRVLFTRSCAIIPTVFVAAFKDVEHLTGMNDLLNVLQSILLPFALLPVLTFTSMRPLMCDFVNGLIGKIVAILLIALIMAINLYFVFVYI 498
[Close]
BLAST of slc11a-1 vs. Ensembl Xenopus
Match: SLC11A1 (solute carrier family 11 member 1 [Source:NCBI gene;Acc:100498626])

HSP 1 Score: 576.244 bits (1484), Expect = 0.000e+0
Identity = 295/438 (67.35%), Postives = 356/438 (81.28%), Query Frame = 2 
Query:  206 RSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFI 1519
            +  FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQ GAIA FKLLW+LL AT+LGL+ QRLA RLGVVTG  LA++C   YPK PR ILW+++EIAIIGSDMQEVIGTAIAF+LLS+G IPLWGGV++TIIDT  FLFLDKYGLRKLEAFFA+LIT M   FGY+Y+VVKP+Q EVLKGMF PYC  CGS ELLQAVGIIGA+IMPHNIYLHS+LVKSR ++R  + ++ EAN YY+IES +ALF+SFLIN+FV++VFAE FY K      + C+ +  PH +VF S++    +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTYAGQF MEGFLNL W R+ RVL TRS AI PT+F+A ++ + +LT MNDLLNVL S+ LPFA++P+LTFTS + +M +F NG I  ++ + L   ++ IN+YFV V+I
Sbjct:   15 QPGFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQCGAIAGFKLLWVLLGATVLGLLCQRLAVRLGVVTGMDLAQICRYYYPKAPRWILWILVEIAIIGSDMQEVIGTAIAFSLLSSGRIPLWGGVLITIIDTLFFLFLDKYGLRKLEAFFALLITIMAVTFGYEYVVVKPDQREVLKGMFYPYCSGCGSPELLQAVGIIGAIIMPHNIYLHSSLVKSRVVDRKQKQEVSEANMYYMIESSIALFVSFLINLFVMAVFAEAFYNKTNQDAYDVCQNSSSPHADVFPSNNDSLSVDIYKGGVILGCFFGPAALYIWAVGILAAGQSSTMTGTYAGQFVMEGFLNLKWSRFYRVLFTRSCAIIPTVFVAAFKDVEHLTGMNDLLNVLQSILLPFALLPVLTFTSMRPLMCDFVNGLIGKIVAILLIALIMAINLYFVFVYI 452
[Close]
BLAST of slc11a-1 vs. Ensembl Xenopus
Match: rtn1 (reticulon 1 [Source:Xenbase;Acc:XB-GENE-1011333])

HSP 1 Score: 575.859 bits (1483), Expect = 0.000e+0
Identity = 312/480 (65.00%), Postives = 381/480 (79.38%), Query Frame = 2 
Query:   89 NKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVF-NSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG-RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            N +D + E +  VE      +TYF E++ IP+D+      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSG++A FKLLW+LL AT++GL++QRLAARLGVVTG HLAEVC ++YPK+PRIILW+M+E+AIIGSDMQEVIG+AIA NLLS G+IPLWGGV++TIIDTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ V PNQ E+LKGMF PYC++CG+ +L QAVGI+GAVIMPHN+YLHSALVKSR INR  + ++REAN Y+ IES +ALFISFLINVFVV+VFAE FYGK    +  EC     P   +F N++D L  +DI+KGG+ LGC FG   LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS   +M+EF NG +  S + + + C+   IN+YFV+V++ 
Sbjct:   26 NLSDTSPEPAVEVEP----FATYFDEKIPIPEDE----THSWFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGSVAGFKLLWVLLAATIIGLLLQRLAARLGVVTGLHLAEVCNRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIALNLLSAGIIPLWGGVLITIIDTFFFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVRVSPNQGELLKGMFFPYCKDCGAPQLEQAVGIVGAVIMPHNMYLHSALVKSREINRANKKEVREANKYFFIESSIALFISFLINVFVVAVFAEAFYGKTNQEVFNECLNKSSPQSNLFPNNTDPL-QVDIFKGGVVLGCFFGAPALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVFLTRSIAITPTLLVAIFQDVQHLTGMNDFLNVLQSLQLPFALIPILTFTSLPSVMSEFANGIKFISRILILIVCS---INMYFVVVYVS 493
[Close]
BLAST of slc11a-1 vs. Ensembl Xenopus
Match: rtn1 (reticulon 1 [Source:Xenbase;Acc:XB-GENE-1011333])

HSP 1 Score: 575.859 bits (1483), Expect = 0.000e+0
Identity = 312/482 (64.73%), Postives = 382/482 (79.25%), Query Frame = 2 
Query:   89 NKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVF-NSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            N +D + E +  VE      +TYF E++ IP+D+      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSG++A FKLLW+LL AT++GL++QRLAARLGVVTG HLAEVC ++YPK+PRIILW+M+E+AIIGSDMQEVIG+AIA NLLS G+IPLWGGV++TIIDTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ V PNQ E+LKGMF PYC++CG+ +L QAVGI+GAVIMPHN+YLHSALVKSR INR  + ++REAN Y+ IES +ALFISFLINVFVV+VFAE FYGK    +  EC     P   +F N++D L  +DI+KGG+ LGC FG   LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS   +M+EF NG   +I+  + + + C+   IN+YFV+V++ 
Sbjct:   26 NLSDTSPEPAVEVEP----FATYFDEKIPIPEDE----THSWFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGSVAGFKLLWVLLAATIIGLLLQRLAARLGVVTGLHLAEVCNRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIALNLLSAGIIPLWGGVLITIIDTFFFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVRVSPNQGELLKGMFFPYCKDCGAPQLEQAVGIVGAVIMPHNMYLHSALVKSREINRANKKEVREANKYFFIESSIALFISFLINVFVVAVFAEAFYGKTNQEVFNECLNKSSPQSNLFPNNTDPL-QVDIFKGGVVLGCFFGAPALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVFLTRSIAITPTLLVAIFQDVQHLTGMNDFLNVLQSLQLPFALIPILTFTSLPSVMSEFANGIGWKIAGGILILIVCS---INMYFVVVYVS 495
[Close]
BLAST of slc11a-1 vs. Ensembl Mouse
Match: Slc11a2 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 [Source:MGI Symbol;Acc:MGI:1345279])

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 307/461 (66.59%), Postives = 379/461 (82.21%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E++ IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLAT++GL++QRLAARLGVVTG HLAEVC+++YPK+PRIILW+M+E+AIIGSDMQEVIG+AIA NLLS G +PLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+YI VKP+Q++VL+GMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NR  + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+ K    +VE CK N  PH ++F S ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M+EF NG   RI+  + V + C+   IN+YFV+V++Q
Sbjct:   48 TTYFDEKIPIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYITVKPSQSQVLRGMFVPSCPGCRTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNKQVVEVCKNNSSPHADLFPSDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLIVCS---INMYFVVVYVQ 500
[Close]
BLAST of slc11a-1 vs. Ensembl Mouse
Match: Slc11a2 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 [Source:MGI Symbol;Acc:MGI:1345279])

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 307/461 (66.59%), Postives = 379/461 (82.21%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E++ IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLAT++GL++QRLAARLGVVTG HLAEVC+++YPK+PRIILW+M+E+AIIGSDMQEVIG+AIA NLLS G +PLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+YI VKP+Q++VL+GMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NR  + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+ K    +VE CK N  PH ++F S ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M+EF NG   RI+  + V + C+   IN+YFV+V++Q
Sbjct:   48 TTYFDEKIPIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYITVKPSQSQVLRGMFVPSCPGCRTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNKQVVEVCKNNSSPHADLFPSDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLIVCS---INMYFVVVYVQ 500
[Close]
BLAST of slc11a-1 vs. Ensembl Mouse
Match: Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 [Source:MGI Symbol;Acc:MGI:1345275])

HSP 1 Score: 524.242 bits (1349), Expect = 0.000e+0
Identity = 279/459 (60.78%), Postives = 353/459 (76.91%), Query Frame = 2 
Query:  152 TYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHW-EVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQT 1525
            TY  E++ IP  D+G      FS +KLWAFTGPGFLMSIA+LDPGNIESDLQ+GA+A FKLLW+LL AT+LGL+ QRLAARLGVVTG  L EVC+  YPK+PRI+LW+ IE+AI+GSDMQEVIGTAI+FNLLS G IPLW GV++TI+DTF FLFLD YGLRKLEAFF +LIT M   FGY+Y+V  P+Q  +LKG+ +P C  CG  ELLQAVGI+GA+IMPHNIYLHSALVKSR ++R  R  +REAN Y+LIE+ +AL +SF+IN+FV++VF + FY +        C  + + ++ ++F   +    +DIY+GG+ LGC FG A LYIWA+G+LAAGQSSTMTGTYAGQF MEGFL L W R+ RVLLTRS AI PT+ +A ++ + +L+ +NDLLNVL S+ LPFA++PILTFTS   +M EF NGR+S  +T  +   V  IN+YFVI ++ +
Sbjct:   34 TYLSEKIPIPSADQGT-----FSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWDGVLITIVDTFFFLFLDNYGLRKLEAFFGLLITIMALTFGYEYVVAHPSQGALLKGLVLPTCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKSREVDRTRRVDVREANMYFLIEATIALSVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLQNYAKIFPRDNNTVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLKDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQEFANGRMSKAITSCIMALVCAINLYFVISYLPS 487
[Close]
BLAST of slc11a-1 vs. Ensembl Mouse
Match: Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 [Source:MGI Symbol;Acc:MGI:1345275])

HSP 1 Score: 446.047 bits (1146), Expect = 7.771e-151
Identity = 229/386 (59.33%), Postives = 294/386 (76.17%), Query Frame = 2 
Query:  371 MMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHW-EVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQT 1525
            + QRLAARLGVVTG  L EVC+  YPK+PRI+LW+ IE+AI+GSDMQEVIGTAI+FNLLS G IPLW GV++TI+DTF FLFLD YGLRKLEAFF +LIT M   FGY+Y+V  P+Q  +LKG+ +P C  CG  ELLQAVGI+GA+IMPHNIYLHSALVKSR ++R  R  +REAN Y+LIE+ +AL +SF+IN+FV++VF + FY +        C  + + ++ ++F   +    +DIY+GG+ LGC FG A LYIWA+G+LAAGQSSTMTGTYAGQF MEGFL L W R+ RVLLTRS AI PT+ +A ++ + +L+ +NDLLNVL S+ LPFA++PILTFTS   +M EF NGR+S  +T  +   V  IN+YFVI ++ +
Sbjct:   61 LCQRLAARLGVVTGKDLGEVCHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAISFNLLSAGRIPLWDGVLITIVDTFFFLFLDNYGLRKLEAFFGLLITIMALTFGYEYVVAHPSQGALLKGLVLPTCPGCGQPELLQAVGIVGAIIMPHNIYLHSALVKSREVDRTRRVDVREANMYFLIEATIALSVSFIINLFVMAVFGQAFYQQTNEEAFNICANSSLQNYAKIFPRDNNTVSVDIYQGGVILGCLFGPAALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLVAVFRDLKDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPAVMQEFANGRMSKAITSCIMALVCAINLYFVISYLPS 446
[Close]
BLAST of slc11a-1 vs. Ensembl Mouse
Match: Slc11a2 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 [Source:MGI Symbol;Acc:MGI:1345279])

HSP 1 Score: 242.662 bits (618), Expect = 6.886e-76
Identity = 118/194 (60.82%), Postives = 148/194 (76.29%), Query Frame = 2 
Query:  950 INVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            INVFVVSVFAE F+ K    +VE CK N  PH ++F S ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M+EF NG   RI+  + V + C+   IN+YFV+V++Q
Sbjct:    1 INVFVVSVFAEAFFEKTNKQVVEVCKNNSSPHADLFPSDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLIVCS---INMYFVVVYVQ 191
[Close]
BLAST of slc11a-1 vs. UniProt/SwissProt
Match: sp|P49282|NRAM2_MOUSE (Natural resistance-associated macrophage protein 2 OS=Mus musculus OX=10090 GN=Slc11a2 PE=1 SV=2)

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 307/461 (66.59%), Postives = 379/461 (82.21%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E++ IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLAT++GL++QRLAARLGVVTG HLAEVC+++YPK+PRIILW+M+E+AIIGSDMQEVIG+AIA NLLS G +PLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+YI VKP+Q++VL+GMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NR  + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+ K    +VE CK N  PH ++F S ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M+EF NG   RI+  + V + C+   IN+YFV+V++Q
Sbjct:   48 TTYFDEKIPIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYITVKPSQSQVLRGMFVPSCPGCRTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNKQVVEVCKNNSSPHADLFPSDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLIVCS---INMYFVVVYVQ 500
[Close]
BLAST of slc11a-1 vs. UniProt/SwissProt
Match: sp|P49283|MVL_DROME (Protein Malvolio OS=Drosophila melanogaster OX=7227 GN=Mvl PE=2 SV=2)

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 300/466 (64.38%), Postives = 364/466 (78.11%), Query Frame = 2 
Query:  143 AASTYF-QERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSD-----ALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQ 1522
            A   YF  E+V IPDDD        FSF+KLWAFTGPGFLMSIAYLDPGNIESD+QSGA A++K+LW+LL AT+LGL+MQRLAARLGVVTG HLAE+CY++Y ++PR ILW+MIEIAIIGSDMQEVIGTAIA  LLSN V+PLWGGV++TI+DTFTFLFLDKYGLRKLE  F  LIT M  +FGY+YIV  PNQ EVL+GMFVP+C NC S  LLQAVG++GAVIMPHN+YLHSALVKSR+I+R    K+ EANFY+ IE+ VALF+SF+IN+FVV+VFA G YGK    +VE CK   +      +  D     A+ D D+YKGG+FLGC FG   +YIW +GILAAGQSSTMTGTYAGQF+MEGFLNL W RW RVL+TR IAI PT  +A +  + +LT MND+LN +MS+QLPFA IP + FTS   +M EF NG  + ++++ L   VIG+N+YFV+V ++
Sbjct:   50 AKQAYFSDEKVLIPDDDS---TNVGFSFRKLWAFTGPGFLMSIAYLDPGNIESDMQSGAAAKYKILWVLLWATVLGLLMQRLAARLGVVTGLHLAEMCYRQYKRLPRWILWIMIEIAIIGSDMQEVIGTAIAIYLLSNKVVPLWGGVLITIVDTFTFLFLDKYGLRKLEFLFGTLITIMAVSFGYEYIVSAPNQGEVLEGMFVPWCSNCNSNVLLQAVGVVGAVIMPHNLYLHSALVKSRDIDRRQTKKVSEANFYFFIEASVALFVSFIINLFVVAVFAHGMYGKTNNDVVEVCKDKSMYEDAKMSFVDNVNGTAIIDADLYKGGLFLGCTFGAVAMYIWGVGILAAGQSSTMTGTYAGQFSMEGFLNLQWPRWCRVLVTRCIAIIPTFCLAMFSKMEDLTSMNDILNAVMSLQLPFAAIPTIAFTSCAAIMGEFVNGLGNKIVSILLTIVVIGVNLYFVVVQVE 512
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BLAST of slc11a-1 vs. UniProt/SwissProt
Match: sp|O54902|NRAM2_RAT (Natural resistance-associated macrophage protein 2 OS=Rattus norvegicus OX=10116 GN=Slc11a2 PE=1 SV=1)

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 303/461 (65.73%), Postives = 379/461 (82.21%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E++ IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLAT++GL++QRLAARLGVVTG HLAEVC+++YPK+PRIILW+M+E+AIIGSDMQEVIG+AIA NLLS G +PL+GGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ VKP+Q++VL+GMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NR  + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+ K    +VE C+ +  PH ++F + ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M+EF NG   RI+  + V L C+   IN+YFV+V++Q
Sbjct:   48 TTYFDEKIPIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFEKTNEQVVEVCRNSSSPHADLFPNDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVILTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSEFSNGIGWRIAGGILVLLVCS---INMYFVVVYVQ 500
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BLAST of slc11a-1 vs. UniProt/SwissProt
Match: sp|P49281|NRAM2_HUMAN (Natural resistance-associated macrophage protein 2 OS=Homo sapiens OX=9606 GN=SLC11A2 PE=1 SV=2)

HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0
Identity = 305/461 (66.16%), Postives = 378/461 (82.00%), Query Frame = 2 
Query:  149 STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQ 1522
            +TYF E+++IP+++      S FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA+A FKLLW+LLLATL+GL++QRLAARLGVVTG HLAEVC+++YPK+PR+ILW+M+E+AIIGSDMQEVIG+AIA NLLS G IPLWGGV++TI DTF FLFLDKYGLRKLEAFF  LIT M   FGY+Y+ VKP+Q++VLKGMFVP C  C + ++ QAVGI+GAVIMPHN+YLHSALVKSR +NRN + ++REAN Y+ IES +ALF+SF+INVFVVSVFAE F+GK    +VE C     PH  +F   ++   +DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RV+LTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS + +M++F NG   RI+  + V + C+   IN+YFV+V+++
Sbjct:   48 ATYFNEKISIPEEE-----YSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICS---INMYFVVVYVR 500
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BLAST of slc11a-1 vs. UniProt/SwissProt
Match: sp|P51027|NRAM1_CHICK (Natural resistance-associated macrophage protein 1 OS=Gallus gallus OX=9031 GN=SLC11A1 PE=2 SV=1)

HSP 1 Score: 550.051 bits (1416), Expect = 0.000e+0
Identity = 286/483 (59.21%), Postives = 367/483 (75.98%), Query Frame = 2 
Query:   83 SMNKNDINAESSAIVESNSTA-ASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHW-EVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQT 1525
            S+N+   +A +  +   +    A TY  E ++IP           FSF+KLWAFTGPGFLMSIAYLDPGN+ESDLQ GA+A FKLLW+LL AT+LGL+ QRLA RLGVVTG  LAE+CY  YP++PR++LW+M+EIAIIGSDMQEVIGTAIAF+LLS G IPLWGGV++TI DT  FLFLDKYGLRKLEAFF  LIT M   FGY+Y++V+P Q EVLKG+F+PYC  CG +ELLQAVGI+GA+IMPHNI+LHS+LVK+R I+R+ + +++EAN Y+L ES +ALF+SFLIN+FV++VF E FY +    +  +C  + +  +  +F  ++    +DIY+GG+ LGC FG A LYIWA+GILAAGQSSTMTGTYAGQF MEGFL L W R+ RVL TRS+AI PT+F+A ++ +  LT MNDLLNVL S+ LPFA++P+LTFTS + +M +F NG +  +L   +   V  IN+YFV+ F+ T
Sbjct:   18 SLNRGQTDASNVPVPPHHPVPHAQTYLDELISIPKGST-----PGFSFRKLWAFTGPGFLMSIAYLDPGNVESDLQCGAVAGFKLLWVLLWATVLGLLCQRLAIRLGVVTGKDLAEICYLYYPRVPRVLLWLMMEIAIIGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITITDTLFFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVMVRPAQTEVLKGIFLPYCPGCGREELLQAVGIVGAIIMPHNIFLHSSLVKTRAIDRSKKEEVKEANMYFLTESCLALFVSFLINLFVMAVFGEAFYHQRNEDVHNKCVNSSVSRYASIFPINNETVSVDIYQGGVILGCYFGAAALYIWAVGILAAGQSSTMTGTYAGQFVMEGFLQLRWSRFTRVLFTRSLAILPTLFVAAFRDVSQLTGMNDLLNVLQSILLPFAVLPVLTFTSLRPLMHDFANGLLGQVLMSLITGLVCAINVYFVVDFLPT 495
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BLAST of slc11a-1 vs. TrEMBL
Match: A0A0H3YJ20 (Slc11a-1 OS=Schmidtea mediterranea OX=79327 GN=slc11a-1 PE=2 SV=1)

HSP 1 Score: 1005.74 bits (2599), Expect = 0.000e+0
Identity = 542/542 (100.00%), Postives = 542/542 (100.00%), Query Frame = 2 
Query:   86 MNKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWVXXXXXXXXXXXXXXXXVYLCLYGLVENNKLRKLILGNCWRLFGDLMIYRSINEVS 1711
            MNKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKLLWLLLLATLLGLMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSRNINRNIRAKIREANFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWVYYLLISIFLALYLLFIVYLCLYGLVENNKLRKLILGNCWRLFGDLMIYRSINEVS
Sbjct:    1 MNKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKLLWLLLLATLLGLMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSRNINRNIRAKIREANFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWVYYLLISIFLALYLLFIVYLCLYGLVENNKLRKLILGNCWRLFGDLMIYRSINEVS 542
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BLAST of slc11a-1 vs. TrEMBL
Match: R7VCE5 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_224895 PE=3 SV=1)

HSP 1 Score: 650.203 bits (1676), Expect = 0.000e+0
Identity = 337/473 (71.25%), Postives = 396/473 (83.72%), Query Frame = 2 
Query:  125 VESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFW 1543
            ++SN + ASTYF +++ IPD  +     + FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQ+KLLWLLLLAT+LGL+MQRLAARLGVVTG HLAEVC ++YPK+PRI+LW+M+EIAIIGSDMQEVIGTAIA  +LSNG IPLWGGV++T++DTFTFL LDKYGLRKLEAFF  LIT M  +FGY+Y++V PNQ EVLKGMF PYCE CGSKELLQAVGIIGAVIMPHNIYLHSALVKSR+I+R+ + +++EAN YY IE+GVALF+SFLINVFVVSVFA GFYGKN+T I   C    IPH E+FN S    ++D++ GG+FLGC FGLA +YIWAIGILAAGQSSTMTGTYAGQFAMEGFL+L WKRWQRVLLTRSIAI PTIF+A ++GI  LT MNDLLNVLMS+QLPFA++PILTFTSS   M +FKNG  + ++   L   V  IN+YF  V+I+   +  W
Sbjct:   38 IQSNVSVASTYFDQKIEIPDTGD-----AKFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQYKLLWLLLLATILGLLMQRLAARLGVVTGLHLAEVCCRQYPKLPRILLWLMVEIAIIGSDMQEVIGTAIAIFILSNGKIPLWGGVLITVVDTFTFLLLDKYGLRKLEAFFGFLITVMAISFGYEYVLVAPNQGEVLKGMFFPYCEGCGSKELLQAVGIIGAVIMPHNIYLHSALVKSRSIDRSKKTEVKEANMYYFIEAGVALFVSFLINVFVVSVFASGFYGKNSTEIYTNCVNGSIPHAEIFNHSGT-AEVDLFSGGVFLGCEFGLAAMYIWAIGILAAGQSSTMTGTYAGQFAMEGFLDLKWKRWQRVLLTRSIAILPTIFLAAFRGIDELTGMNDLLNVLMSLQLPFALLPILTFTSSGYCMGDFKNGWFNKVVGCALTVAVFAINLYFFSVYIEPLQTLHW 504
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BLAST of slc11a-1 vs. TrEMBL
Match: V4C557 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_143684 PE=3 SV=1)

HSP 1 Score: 649.047 bits (1673), Expect = 0.000e+0
Identity = 330/479 (68.89%), Postives = 402/479 (83.92%), Query Frame = 2 
Query:  110 ESSAIVE-SNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFW 1543
            E+S + + S +T ASTYF E++ IPD     D+   FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSG++AQF+LLW+L+ AT+LGL+MQRLAARLGVVTG HLAEVCY++YP +PR++LW+M+EIAIIGSDMQEVIGTAIA  LLS+G +PL+ GVI+TI DTFTFL LDKYGLRKLE FFA LI  M   FGY+YIVV PNQA+V+KG+FVPYCE CGSK+LLQAVG+IGA+IMPHNIYLHSALVKSR ++R+ R +IREAN Y+LIE+ +ALFISFLINVFVV+VFAEGF+ +    + E+C+A   PH  VFN++D    +DIYKGG+FLGC+FG+A +YIW +GILAAGQSSTMTGTY GQF MEGFLNL WKRWQRVLLTR+IAI PT+FIA Y+GI NLT MNDLLNVLMS+QLPFA++PILTFTS+K +M EF NGR + +LT  LA  VI IN++FV+ +++  + + W
Sbjct:   12 ETSPVKKGSVTTVASTYFSEQIPIPD----ADNYKMFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGSVAQFRLLWVLMGATILGLLMQRLAARLGVVTGMHLAEVCYRQYPIVPRLLLWLMVEIAIIGSDMQEVIGTAIAIYLLSDGKVPLYAGVIITIADTFTFLLLDKYGLRKLEGFFAFLILVMAVTFGYEYIVVAPNQAQVVKGLFVPYCEGCGSKQLLQAVGVIGAIIMPHNIYLHSALVKSREVDRSKRPEIREANKYFLIEAIIALFISFLINVFVVAVFAEGFFNQTNHDLFEKCEAQGNPHASVFNNTDQEISVDIYKGGVFLGCKFGIAAMYIWGVGILAAGQSSTMTGTYTGQFVMEGFLNLKWKRWQRVLLTRTIAILPTVFIAIYEGIENLTVMNDLLNVLMSLQLPFALLPILTFTSAKGLMDEFVNGRTTKILTALLAIVVIAINLFFVVEYLE-KLPDHW 485
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BLAST of slc11a-1 vs. TrEMBL
Match: A0A210PS89 (Natural resistance-associated macrophage protein 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19887 PE=3 SV=1)

HSP 1 Score: 643.269 bits (1658), Expect = 0.000e+0
Identity = 335/509 (65.82%), Postives = 419/509 (82.32%), Query Frame = 2 
Query:   95 NDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWVXXXXXXXXXXXXXXXXVYLCLYGLV 1621
              +N+E  ++   N T ASTYF ERV +P  D      + FSF+KLWAFTGPGFLMSIAYLDPGN+ESDL++GA AQFKLLW+L+++T+LGL+MQRLAARLGVVTG HLAE+C++RYPK+PRIILWVM+EIAIIGSD+QEVIGTAIA ++LSNG IPL+GGV++TIIDTFTFL LD+YGLRKLEAFF  LIT M  +FGY+Y+VV PNQ +V+KGMF PYCENCGS ELLQ +GI+GA+IMPHNIYLHSALVKSR++NR  +A + EAN Y+ IE+ +ALF+SFLINVFV ++FAEGFYG+++  I   C     P+ ++FN+S  + D+DIY+GGI+LGC++G+A +YIWA+GILAAGQSSTMTGTY+GQFAMEGFLNL WKRWQRVL TRSIAI PT+FIA Y+GI +LT MNDLLNVLMS+QLPFA+IPILTFT+S+++M +FKNG  + +LT  L+  VI IN+YFV V+I   + + W  YL I++ L  Y+LF  YL  Y L+
Sbjct:    3 TSVNSEKKSV---NDTTASTYFDERVAVPPPDG-----TRFSFRKLWAFTGPGFLMSIAYLDPGNVESDLRAGASAQFKLLWILMISTVLGLLMQRLAARLGVVTGLHLAEICFKRYPKVPRIILWVMVEIAIIGSDIQEVIGTAIAISILSNGKIPLYGGVLITIIDTFTFLLLDRYGLRKLEAFFCFLITVMSISFGYEYVVVHPNQPQVMKGMFFPYCENCGSDELLQGIGIVGAIIMPHNIYLHSALVKSRDVNRKQKAAVSEANLYFFIEAAIALFVSFLINVFVTAIFAEGFYGRSSQEIYHICTNASSPYADLFNNSHVVADVDIYRGGIYLGCKYGIAAMYIWAVGILAAGQSSTMTGTYSGQFAMEGFLNLKWKRWQRVLFTRSIAILPTVFIAIYKGIGDLTDMNDLLNVLMSLQLPFALIPILTFTNSEKLMGDFKNGLFTKILTSVLSVVVIVINLYFVAVYIPV-LPHHWAMYLFIALILTFYVLFTAYLTWYCLI 502
[Close]
BLAST of slc11a-1 vs. TrEMBL
Match: Q4W8C5 (Divalent metal transporter OS=Mizuhopecten yessoensis OX=6573 GN=dmt PE=2 SV=1)

HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0
Identity = 333/509 (65.42%), Postives = 417/509 (81.93%), Query Frame = 2 
Query:   95 NDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWVXXXXXXXXXXXXXXXXVYLCLYGLV 1621
              +N+E  ++   N T ASTYF ERV +P  D      + FSF+KLWAFTGPGFLMSIAYLDPGN+ESDL++GA AQFKLLW+L+++T+LGL+MQRLAARLGVVTG HLAE+C++RYPK+PRIILWVM+EIAIIGSD+QEVIGTAIA ++LSNG IPL+GGV++TIIDTFTFL LD+YGLRKLEAFF  LIT M  +FGY+Y+VV PNQ +V+KGMF PYCENCGS ELLQ +GI+GA+IMPHNIYLHSALVKSR++NR  +A + EAN Y+ IE+ +ALF+SFLINVFV ++FAEGFYG+++  I   C     P+ ++FN+S  + D+DIY+GGI+LGC++G+A +YIWA+GILAAGQSSTMTGTY+GQFAMEGFLNL WKRWQRVL TRSI I PT+FI  Y+GI +LT MNDLLNVLMS+QLPFA+IPILTFT+S+++M +FKNG  + +LT  L+  VI IN+YFV V+I   + + W  YL I++ L  Y+LF  YL  Y L+
Sbjct:    3 TSVNSEKKSV---NETTASTYFDERVAVPPPDG-----TRFSFRKLWAFTGPGFLMSIAYLDPGNVESDLRAGASAQFKLLWILMISTVLGLLMQRLAARLGVVTGLHLAEICFKRYPKVPRIILWVMVEIAIIGSDIQEVIGTAIAISILSNGKIPLYGGVLITIIDTFTFLLLDRYGLRKLEAFFCFLITVMSISFGYEYVVVHPNQPQVMKGMFFPYCENCGSDELLQGIGIVGAIIMPHNIYLHSALVKSRDVNRKQKAAVSEANLYFFIEAAIALFVSFLINVFVTAIFAEGFYGRSSQEIYHICTNASSPYADLFNNSHVVADVDIYRGGIYLGCKYGIAAMYIWAVGILAAGQSSTMTGTYSGQFAMEGFLNLKWKRWQRVLFTRSIPILPTVFIPIYKGIGDLTDMNDLLNVLMSLQLPFALIPILTFTNSEKLMGDFKNGLFTKILTSVLSVVVIVINLYFVAVYIPV-LPHHWAMYLFIALILTFYVLFTAYLTWYCLI 502
[Close]
BLAST of slc11a-1 vs. Ensembl Cavefish
Match: slc11a2 (natural resistance-associated macrophage protein 2 [Source:NCBI gene;Acc:103037062])

HSP 1 Score: 584.719 bits (1506), Expect = 0.000e+0
Identity = 311/471 (66.03%), Postives = 377/471 (80.04%), Query Frame = 2 
Query:  116 SAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFI 1519
            +A   S     STYF+E++ IPDD   +     FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA A FKLLW+LL +T++GL++QRLAARLGVVTG HLAEVC ++YP +PRIILW+M+E+AIIGSDMQEVIG AIAFNLLS G IPLW GV++TIIDTF FLFLDKYGLRKLEAFF +LIT M  +FGY+Y++V PNQ EVLKGMFVPYCE CG  +L QAVG++GAVIMPHNIYLHSALVKSR ++RN + +++EAN YY IES +ALF+SFLINVFVV+VFAE FY K    + ++C  +  PH ++F +++    +DIYKGG+ LGC FG A LYIWAIGILAAGQSSTMTGTY+GQF MEGFLNL W R+ RVLLTRSIAI PT+ +A +Q + +LT MND LNVL SMQLPFA+IPILTFTS   +M +F NG   +I   +T+ + C    IN+YFV+V++
Sbjct:   28 AASPSSQEEPISTYFEEKIPIPDDATQI-----FSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWVLLASTIIGLLLQRLAARLGVVTGMHLAEVCNRQYPTVPRIILWLMVELAIIGSDMQEVIGCAIAFNLLSVGRIPLWAGVLITIIDTFVFLFLDKYGLRKLEAFFGILITIMALSFGYEYVMVAPNQVEVLKGMFVPYCEGCGPVQLEQAVGVVGAVIMPHNIYLHSALVKSRQVDRNNKKEVKEANKYYFIESSIALFVSFLINVFVVAVFAEAFYDKTNIQVNQQCNESGSPHTDLFPTNNETLQVDIYKGGVVLGCFFGPAALYIWAIGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIFPTLLVAIFQDVQHLTGMNDFLNVLQSMQLPFALIPILTFTSLTSIMNDFANGLVWKIGGGMTILMVC---AINMYFVVVYV 490
[Close]
BLAST of slc11a-1 vs. Ensembl Cavefish
Match: slc11a2 (natural resistance-associated macrophage protein 2 [Source:NCBI gene;Acc:103037062])

HSP 1 Score: 584.334 bits (1505), Expect = 0.000e+0
Identity = 311/471 (66.03%), Postives = 377/471 (80.04%), Query Frame = 2 
Query:  116 SAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFI 1519
            +A   S     STYF+E++ IPDD   +     FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA A FKLLW+LL +T++GL++QRLAARLGVVTG HLAEVC ++YP +PRIILW+M+E+AIIGSDMQEVIG AIAFNLLS G IPLW GV++TIIDTF FLFLDKYGLRKLEAFF +LIT M  +FGY+Y++V PNQ EVLKGMFVPYCE CG  +L QAVG++GAVIMPHNIYLHSALVKSR ++RN + +++EAN YY IES +ALF+SFLINVFVV+VFAE FY K    + ++C  +  PH ++F +++    +DIYKGG+ LGC FG A LYIWAIGILAAGQSSTMTGTY+GQF MEGFLNL W R+ RVLLTRSIAI PT+ +A +Q + +LT MND LNVL SMQLPFA+IPILTFTS   +M +F NG   +I   +T+ + C    IN+YFV+V++
Sbjct:   32 AASPSSQEEPISTYFEEKIPIPDDATQI-----FSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWVLLASTIIGLLLQRLAARLGVVTGMHLAEVCNRQYPTVPRIILWLMVELAIIGSDMQEVIGCAIAFNLLSVGRIPLWAGVLITIIDTFVFLFLDKYGLRKLEAFFGILITIMALSFGYEYVMVAPNQVEVLKGMFVPYCEGCGPVQLEQAVGVVGAVIMPHNIYLHSALVKSRQVDRNNKKEVKEANKYYFIESSIALFVSFLINVFVVAVFAEAFYDKTNIQVNQQCNESGSPHTDLFPTNNETLQVDIYKGGVVLGCFFGPAALYIWAIGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIFPTLLVAIFQDVQHLTGMNDFLNVLQSMQLPFALIPILTFTSLTSIMNDFANGLVWKIGGGMTILMVC---AINMYFVVVYV 494
[Close]
BLAST of slc11a-1 vs. Ensembl Cavefish
Match: slc11a2 (natural resistance-associated macrophage protein 2 [Source:NCBI gene;Acc:103037062])

HSP 1 Score: 539.65 bits (1389), Expect = 0.000e+0
Identity = 286/418 (68.42%), Postives = 341/418 (81.58%), Query Frame = 2 
Query:  116 SAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQ 1369
            +A   S     STYF+E++ IPDD   +     FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA A FKLLW+LL +T++GL++QRLAARLGVVTG HLAEVC ++YP +PRIILW+M+E+AIIGSDMQEVIG AIAFNLLS G IPLW GV++TIIDTF FLFLDKYGLRKLEAFF +LIT M  +FGY+Y++V PNQ EVLKGMFVPYCE CG  +L QAVG++GAVIMPHNIYLHSALVKSR ++RN + +++EAN YY IES +ALF+SFLINVFVV+VFAE FY K    + ++C  +  PH ++F +++    +DIYKGG+ LGC FG A LYIWAIGILAAGQSSTMTGTY+GQF MEGFLNL W R+ RVLLTRSIAI PT+ +A +Q + +LT MND LNVL SMQ
Sbjct:   29 AASPSSQEEPISTYFEEKIPIPDDATQI-----FSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWVLLASTIIGLLLQRLAARLGVVTGMHLAEVCNRQYPTVPRIILWLMVELAIIGSDMQEVIGCAIAFNLLSVGRIPLWAGVLITIIDTFVFLFLDKYGLRKLEAFFGILITIMALSFGYEYVMVAPNQVEVLKGMFVPYCEGCGPVQLEQAVGVVGAVIMPHNIYLHSALVKSRQVDRNNKKEVKEANKYYFIESSIALFVSFLINVFVVAVFAEAFYDKTNIQVNQQCNESGSPHTDLFPTNNETLQVDIYKGGVVLGCFFGPAALYIWAIGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIFPTLLVAIFQDVQHLTGMNDFLNVLQSMQ 441
[Close]
BLAST of slc11a-1 vs. Ensembl Sea Lamprey
Match: SLC11A2 (solute carrier family 11 member 2 [Source:HGNC Symbol;Acc:HGNC:10908])

HSP 1 Score: 403.29 bits (1035), Expect = 4.495e-137
Identity = 224/326 (68.71%), Postives = 266/326 (81.60%), Query Frame = 2 
Query:  128 ESNSTAA--STYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKG 1099
            ES+   A  STYF +++ +PD   G      FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA A FKLLW+LL +T+LGL++QRLAARLGVVTG HLAEVC + YPKIPRIILW+M+E+AIIGSDMQEVIG+AIA NLLSNG +PL+GGV++TI DTF FLFLDKYGLRKLEAFFAVLITTM   FGYQY++V P+Q E+LKGMF PYCE CG+ +L QAVGI+GAVIMPHNIYLHSALVKSR I+R+ R ++R+AN YY IE+ VALF+SFLINVFVVSVFAE F+GK    +   C  +  PH ++F++      +DIYKG
Sbjct:   39 ESSDAPAEMSTYFDDKIPVPDAGAGT-----FSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWVLLTSTILGLLLQRLAARLGVVTGMHLAEVCNRNYPKIPRIILWLMVELAIIGSDMQEVIGSAIAINLLSNGAVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFAVLITTMAITFGYQYVMVAPDQRELLKGMFFPYCEGCGTPQLEQAVGIVGAVIMPHNIYLHSALVKSRAIDRSKRQEVRDANMYYFIEASVALFVSFLINVFVVSVFAEAFFGKTNNDVRTVCLDHHSPHADMFSNDSNTLQVDIYKG 359
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BLAST of slc11a-1 vs. Ensembl Yeast
Match: SMF1 (Divalent metal ion transporter; broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins [Source:SGD;Acc:S000005482])

HSP 1 Score: 172.94 bits (437), Expect = 4.181e-47
Identity = 135/471 (28.66%), Postives = 219/471 (46.50%), Query Frame = 2 
Query:  104 NAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFS--FKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYG------LRKLEAFFAVLIT--TMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALV---------------------KSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMM 1423
            + + S +V        T+     N   +D  V  R      F K   F GPG ++S+AY+DPGN  + + +GA  QF LL ++LL+  + + +Q L  +LG VTG  L+  C +  P+     L+   E A+I +D+ EVIGTAIA N+L    +PL  GV +T++D F  +F  K G      +R  E F AVL+    + FA    YI    +  +V +G FVP  +      +  A+ I+GA +MPH+++L SALV                     K +           +   Y    + +   + + +    +++F        T  +   C    +    ++NS +A D  D++     L      A   I+ + +L +GQS+ +  T +GQ   EG +N   + WQR L TR I+I P + I+   G   L+   +   V++S+ LPF + P++ FT  K +M
Sbjct:   32 DKKDSTVVIEGEAPVRTFTSSSSNHEREDTYVSKRQVMRDIFAKYLKFIGPGLMVSVAYIDPGNYSTAVDAGASNQFSLLCIILLSNFIAIFLQCLCIKLGSVTGLDLSRACREYLPRWLNWTLYFFAECAVIATDIAEVIGTAIALNILIK--VPLPAGVAITVVDVFLIMFTYKPGASSIRFIRIFECFVAVLVVGVCICFAIELAYIPKSTSVKQVFRG-FVPSAQMFDHNGIYTAISILGATVMPHSLFLGSALVQPRLLDYDVKHGNYTVSEEQDKVKKSKSTEEIMEEKYFNYRPTNAAIKYCMKYSMVELSITLF--------TLALFVNCAILVVAGSTLYNSPEA-DGADLFTIHELLSRNLAPAAGTIFMLALLLSGQSAGVVCTMSGQIVSEGHINWKLQPWQRRLATRCISIIPCLVISICIGREALSKALNASQVVLSIVLPFLVAPLIFFTCKKSIM 490
[Close]
BLAST of slc11a-1 vs. Ensembl Yeast
Match: SMF3 (Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by metal ions; member of the Nramp family of metal transport proteins; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004024])

HSP 1 Score: 164.466 bits (415), Expect = 8.804e-45
Identity = 132/417 (31.65%), Postives = 219/417 (52.52%), Query Frame = 2 
Query:  206 RSHFS-FKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPL-WGGVILTIIDTFTFLFLDKYG--LRKLEAF-FAVLITTMGFAFGYQYIVVK---PNQAEVLKGMFVPYCENCGSKE---LLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMM 1423
            RS+    +K   F GPG L+S+AY+DPGN  + +  GA  ++ LL+ + ++ +  +++Q L  +LG +TG+ LAE C    PK     L++  E+AII +D+ EV+GTAIA  +L    IPL WG ++  +      +F    G  L+K+  F F V I  +G    +   + K   P++AE+ KG F+P   N   KE   L  ++GI+GA +MPH++YL S++VK R  + +++   +      L  S +   +++     ++S+F    +  +   IV     +  P  E     DA D + IYK    L      A   I+A+ +L +GQS+ +  T AGQ   EGFL  +   W   L TR IAI P +F+    G   ++ + +   V++S+ LP    P++ FT+++++M
Sbjct:    2 RSYMQILQKFAKFIGPGILVSVAYMDPGNYATSVSGGAQYKYTLLFSIFISNIFAVLLQCLCVKLGTITGYDLAENCRHNLPKKLNYTLYLFAEVAIIATDLAEVVGTAIALQILFK--IPLTWGVLLTVLDVLVILMFYTPNGQSLKKVRVFEFGVGILVIGTCICFVLELFKVSIPDKAELFKG-FLP--SNIIFKEQQALYISLGILGATVMPHSLYLGSSIVKPRLHDYDLKKYGKVNARPSL--SAIKYTLNYAYAELIISLFLIATFVNSAILIVAGATLSGQPEAE-----DA-DLLSIYK---LLVHYISPAAGLIFALAMLCSGQSAGIICTLAGQIVSEGFLQWSLPPWATRLCTRLIAIVPCLFVTLTMGEKGISDILNFSQVVLSLILPIVSAPLIYFTANRKLM 402
[Close]
BLAST of slc11a-1 vs. Ensembl Yeast
Match: SMF2 (Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins [Source:SGD;Acc:S000001092])

HSP 1 Score: 164.851 bits (416), Expect = 1.922e-44
Identity = 122/416 (29.33%), Postives = 208/416 (50.00%), Query Frame = 2 
Query:  218 SFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDK-----YGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALV---------KSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMM 1423
            + +K   F GPG ++S++Y+DPGN  + + +G+  ++KLL+ +L++  +    Q L ARLG VTG  LA+ C +  P    I L+++ E+AII +D+ EV+GTAI+ N+L +  IPL  GVILT++D    L   K      G+R  EAF ++L+      F  +    K   A+ +   F+P         L  ++ I+GA +MPH++YL S +V         K+ +   +        + Y      ++  + F I   ++S+F        T  +   C    +    ++ S+   ++ D++     L          ++ + +L +GQS+ +  T +GQ   EGFLN T     R   TR++AI P + +    G   L+   +   V++S+ LPF   P+L FTSSK++M
Sbjct:   53 TLRKYARFIGPGLMVSVSYMDPGNYSTAVAAGSAHRYKLLFSVLVSNFMAAFWQYLCARLGAVTGLDLAQNCKKHLPFGLNITLYILAEMAIIATDLAEVVGTAISLNILFH--IPLALGVILTVVDVLIVLLAYKPNGSMKGIRIFEAFVSLLVVLTVVCFTVELFYAKLGPAKEIFSGFLPSKAVFEGDGLYLSLAILGATVMPHSLYLGSGVVQPRLREYDIKNGHYLPDANDMDNNHDNYRPSYEAISETLHFTITELLISLF--------TVALFVNCAILIVSGATLYGSTQNAEEADLFSIYNLLCSTLSKGAGTVFVLALLFSGQSAGIVCTLSGQMVSEGFLNWTVSPALRRSATRAVAITPCLILVLVAGRSGLSGALNASQVVLSLLLPFVSAPLLYFTSSKKIM 458
[Close]
BLAST of slc11a-1 vs. Ensembl Nematostella
Match: EDO43558 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY09])

HSP 1 Score: 582.408 bits (1500), Expect = 0.000e+0
Identity = 300/461 (65.08%), Postives = 368/461 (79.83%), Query Frame = 2 
Query:  146 ASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSS-------DALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNGRISSLLTVFLACTVIGINIYFV 1507
            A TYF +++ IP ++        FS ++LWAFTGPGFLMSIAYLDPGNIESDL+ GA+A+FKLLW+L+LATL+GL+MQRLA RLG VTG HLAEVC  +YP+IPRIILWVM+EIAIIGSDMQEVIGTAIAFNLLSNG IPL+GGV++TI DTF FLFLDKYGLRKLEAFF  LIT M  +FGY+Y VVKP+Q EV+KG+F P C+NC  + +LQ VGI+GAVIMPHN+YLHSALVKSR INR+ +  ++EAN YY IES +ALFISF+IN+FVV+VFAE FYGK    + + C  + IP   VFN++       D ++  D+YKGG+FLGC FG   LY+W+IGILAAGQSSTMTGTY+GQF MEGFLN++W RW+RVL TR IAIAPT+ +AF++G+ +LT MND LNVL S+QLPFA++P+L FTS K +M  F N R+   L   L+  VIGIN++FV
Sbjct:   88 AHTYFDQKIEIPREENDFG----FSLRRLWAFTGPGFLMSIAYLDPGNIESDLRQGAVAKFKLLWVLMLATLMGLIMQRLALRLGTVTGMHLAEVCNAKYPRIPRIILWVMVEIAIIGSDMQEVIGTAIAFNLLSNGKIPLYGGVLITITDTFIFLFLDKYGLRKLEAFFGFLITIMAISFGYEYGVVKPDQVEVVKGLFTPMCKNCNQEAILQGVGIVGAVIMPHNMYLHSALVKSREINRSDKKAVKEANMYYFIESAIALFISFIINIFVVAVFAEAFYGKTYQQVFQGCHDHGIPQINVFNATSQGKHWNDTIEG-DLYKGGVFLGCVFGAPALYVWSIGILAAGQSSTMTGTYSGQFVMEGFLNISWARWKRVLFTRCIAIAPTLAVAFFEGVQDLTGMNDFLNVLQSLQLPFALLPVLHFTSDKSIMDGFANCRVMQGLVWLLSMLVIGINMFFV 543
[Close]
BLAST of slc11a-1 vs. Ensembl Medaka
Match: slc11a2 (natural resistance-associated macrophage protein 2 [Source:NCBI gene;Acc:101175073])

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 304/467 (65.10%), Postives = 371/467 (79.44%), Query Frame = 2 
Query:  128 ESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFI 1519
            E    A STYF+++V+IPD    +     FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA A FKLLW+LL AT++GL++QRLAARLGVVTG HLAEVC ++YP +PRI+LW+M+E+AIIGSDMQEVIG AIAFNLLS G IPLW GV++TI DTF FLFLDKYGLRKLEAFF +LIT M  +FGY+Y++VKP+Q E+LKGMF+PYC  CG  +L QAVGI+GAVIMPHNIYLHSALVKSR+++R  +  ++EAN Y+ IES VALF+SFLINVFVV+VFAE F+ K    +   C A    H ++F  ++   ++DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RVLLTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS   +M +F NG   +IS  + + + C    IN+YFVIV++
Sbjct:   33 EDQDEAFSTYFEQKVHIPDTGNQI-----FSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWVLLGATIIGLLLQRLAARLGVVTGMHLAEVCNRQYPIVPRILLWLMVELAIIGSDMQEVIGCAIAFNLLSVGRIPLWAGVLITITDTFVFLFLDKYGLRKLEAFFGLLITIMAISFGYEYVIVKPDQGELLKGMFLPYCAGCGPVQLEQAVGIVGAVIMPHNIYLHSALVKSRDVDRKNKKDVKEANKYFFIESAVALFVSFLINVFVVAVFAEAFFNKTNMDVNAMCNATGSRHTDLFPMNNDTLEVDIYKGGVVLGCFFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIIPTLLVAIFQDVQHLTGMNDFLNVLQSLQLPFALIPILTFTSLTSIMNDFVNGLVWKISGGILILMVCV---INMYFVIVYV 491
[Close]
BLAST of slc11a-1 vs. Ensembl Medaka
Match: slc11a2 (natural resistance-associated macrophage protein 2 [Source:NCBI gene;Acc:101175073])

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 304/467 (65.10%), Postives = 371/467 (79.44%), Query Frame = 2 
Query:  128 ESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFI 1519
            E    A STYF+++V+IPD    +     FSF+KLWAFTGPGFLMSIAYLDPGNIESDLQSGA A FKLLW+LL AT++GL++QRLAARLGVVTG HLAEVC ++YP +PRI+LW+M+E+AIIGSDMQEVIG AIAFNLLS G IPLW GV++TI DTF FLFLDKYGLRKLEAFF +LIT M  +FGY+Y++VKP+Q E+LKGMF+PYC  CG  +L QAVGI+GAVIMPHNIYLHSALVKSR+++R  +  ++EAN Y+ IES VALF+SFLINVFVV+VFAE F+ K    +   C A    H ++F  ++   ++DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RVLLTRSIAI PT+ +A +Q + +LT MND LNVL S+QLPFA+IPILTFTS   +M +F NG   +IS  + + + C    IN+YFVIV++
Sbjct:   33 EDQDEAFSTYFEQKVHIPDTGNQI-----FSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWVLLGATIIGLLLQRLAARLGVVTGMHLAEVCNRQYPIVPRILLWLMVELAIIGSDMQEVIGCAIAFNLLSVGRIPLWAGVLITITDTFVFLFLDKYGLRKLEAFFGLLITIMAISFGYEYVIVKPDQGELLKGMFLPYCAGCGPVQLEQAVGIVGAVIMPHNIYLHSALVKSRDVDRKNKKDVKEANKYFFIESAVALFVSFLINVFVVAVFAEAFFNKTNMDVNAMCNATGSRHTDLFPMNNDTLEVDIYKGGVVLGCFFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIIPTLLVAIFQDVQHLTGMNDFLNVLQSLQLPFALIPILTFTSLTSIMNDFVNGLVWKISGGILILMVCV---INMYFVIVYV 491
[Close]
BLAST of slc11a-1 vs. Ensembl Medaka
Match: ENSORLT00000020759.2 (natural resistance-associated macrophage protein 2 [Source:NCBI gene;Acc:101155197])

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 294/475 (61.89%), Postives = 375/475 (78.95%), Query Frame = 2 
Query:  131 SNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWV 1546
             N    +TYF ++V++P++D        FS +KLWAFTGPGFLMSIAYLDPGNIESDLQSGA A FKLLWLLL AT++GL++QRLAARLGVVTG HLAEVC+++Y  +PRI+LW+M+E+AIIGSDMQEVIG AIAFNLLS G I LW GV++TI+DTF FLFLDKYGLR+LEAFF +LIT M   FG +Y++V P+Q +++KGMF+PYCE CG  +L QAVG+IGAVIMPHNIYLHSALVKSR ++R+ + +++EAN Y+ IES +ALF+SFL+NVFVV++FAE FY +    +   C  +  PH ++F   +   ++DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RVLLTRSIAI PT+ +A +Q +H+LT MND LNVL SMQLPFA+IPILTFTS   +M+EF NG   +I   + + + C    IN+YFV++++ T +++ W+
Sbjct:   68 DNDLPPTTYFDQKVSVPEEDTA----RFFSLRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWLLLSATIIGLLLQRLAARLGVVTGMHLAEVCHRQYRTVPRILLWLMVELAIIGSDMQEVIGCAIAFNLLSAGRIRLWAGVLITILDTFVFLFLDKYGLRRLEAFFGLLITIMAITFGCEYVMVAPDQGQLIKGMFLPYCEGCGPVQLTQAVGVIGAVIMPHNIYLHSALVKSREVDRSNKKEVKEANKYFFIESAIALFVSFLVNVFVVAIFAEAFYQRTNMEVYTVCNQSGTPHLDLFPLDNNTLEVDIYKGGVVLGCFFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIVPTLLVAIFQDVHHLTGMNDFLNVLQSMQLPFALIPILTFTSLPSLMSEFANGWVFKIGGGVAILIVC---AINMYFVVIYV-TALNSAWL 534
[Close]
BLAST of slc11a-1 vs. Ensembl Medaka
Match: ENSORLT00000027995.1 (natural resistance-associated macrophage protein 2 [Source:NCBI gene;Acc:101155197])

HSP 1 Score: 559.681 bits (1441), Expect = 0.000e+0
Identity = 294/475 (61.89%), Postives = 375/475 (78.95%), Query Frame = 2 
Query:  131 SNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKXXXXXXXXXXXXXMMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLACLYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIAPTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFKNG---RISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWV 1546
             N    +TYF ++V++P++D        FS +KLWAFTGPGFLMSIAYLDPGNIESDLQSGA A FKLLWLLL AT++GL++QRLAARLGVVTG HLAEVC+++Y  +PRI+LW+M+E+AIIGSDMQEVIG AIAFNLLS G I LW GV++TI+DTF FLFLDKYGLR+LEAFF +LIT M   FG +Y++V P+Q +++KGMF+PYCE CG  +L QAVG+IGAVIMPHNIYLHSALVKSR ++R+ + +++EAN Y+ IES +ALF+SFL+NVFVV++FAE FY +    +   C  +  PH ++F   +   ++DIYKGG+ LGC FG A LYIWA+GILAAGQSSTMTGTY+GQF MEGFLNL W R+ RVLLTRSIAI PT+ +A +Q +H+LT MND LNVL SMQLPFA+IPILTFTS   +M+EF NG   +I   + + + C    IN+YFV++++ T +++ W+
Sbjct:   68 DNDLPPTTYFDQKVSVPEEDTA----RFFSLRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAKAGFKLLWLLLSATIIGLLLQRLAARLGVVTGMHLAEVCHRQYRTVPRILLWLMVELAIIGSDMQEVIGCAIAFNLLSAGRIRLWAGVLITILDTFVFLFLDKYGLRRLEAFFGLLITIMAITFGCEYVMVAPDQGQLIKGMFLPYCEGCGPVQLTQAVGVIGAVIMPHNIYLHSALVKSREVDRSNKKEVKEANKYFFIESAIALFVSFLVNVFVVAIFAEAFYQRTNMEVYTVCNQSGTPHLDLFPLDNNTLEVDIYKGGVVLGCFFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLRWSRFARVLLTRSIAIVPTLLVAIFQDVHHLTGMNDFLNVLQSMQLPFALIPILTFTSLPSLMSEFANGWVFKIGGGVAILIVC---AINMYFVVIYV-TALNSAWL 534
[Close]
BLAST of slc11a-1 vs. Planmine SMEST
Match: SMESG000019511.1 (SMESG000019511.1)

HSP 1 Score: 399.823 bits (1026), Expect = 2.684e-137
Identity = 215/216 (99.54%), Postives = 215/216 (99.54%), Query Frame = 2 
Query:  371 MMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVE 1018
            MMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSRNINRNIRAKIREANFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIV 
Sbjct:    1 MMQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSRNINRNIRAKIREANFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVS 216
[Close]
BLAST of slc11a-1 vs. Planmine SMEST
Match: SMESG000019511.1 (SMESG000019511.1)

HSP 1 Score: 397.512 bits (1020), Expect = 1.769e-136
Identity = 214/215 (99.53%), Postives = 214/215 (99.53%), Query Frame = 2 
Query:  374 MQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSXXXXXXXXXXXXXXXFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVE 1018
            MQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSRNINRNIRAKIREANFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIV 
Sbjct:    1 MQRLAARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIAFNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFAFGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYLHSALVKSRNINRNIRAKIREANFYYLIESGVALFISFLINVFVVSVFAEGFYGKNTTTIVS 215
[Close]
BLAST of slc11a-1 vs. Planmine SMEST
Match: SMESG000019504.1 (SMESG000019504.1)

HSP 1 Score: 172.94 bits (437), Expect = 1.524e-51
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 2 
Query:   86 MNKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFK 331
            MNKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFK
Sbjct:    1 MNKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLWAFTGPGFLMSIAYLDPGNIESDLQSGAIAQFK 82
The following BLAST results are available for this feature:
BLAST of slc11a-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SLC11A20.000e+066.16solute carrier family 11 member 2 [Source:HGNC Sym... [more]
SLC11A20.000e+066.16solute carrier family 11 member 2 [Source:HGNC Sym... [more]
SLC11A20.000e+066.16solute carrier family 11 member 2 [Source:HGNC Sym... [more]
SLC11A20.000e+066.16solute carrier family 11 member 2 [Source:HGNC Sym... [more]
SLC11A20.000e+066.16solute carrier family 11 member 2 [Source:HGNC Sym... [more]
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BLAST of slc11a-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
smf-10.000e+056.44NRAMP-like transporter smf-1 [Source:UniProtKB/Sw... [more]
smf-25.681e-17055.14NRAMP-like transporter smf-2 [Source:UniProtKB/Sw... [more]
smf-31.524e-16356.74NRAMP-like transporter smf-3 [Source:UniProtKB/Sw... [more]
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BLAST of slc11a-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mvl0.000e+064.38gene:FBgn0011672 transcript:FBtr0306350[more]
Mvl0.000e+064.38gene:FBgn0011672 transcript:FBtr0306351[more]
Mvl0.000e+064.38gene:FBgn0011672 transcript:FBtr0301477[more]
Mvl0.000e+064.38gene:FBgn0011672 transcript:FBtr0089521[more]
Mvl0.000e+064.38gene:FBgn0011672 transcript:FBtr0301478[more]
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BLAST of slc11a-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
slc11a22.121e-6259.06solute carrier family 11 member 2 [Source:ZFIN;Acc... [more]
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BLAST of slc11a-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SLC11A10.000e+064.79solute carrier family 11 member 1 [Source:NCBI gen... [more]
SLC11A10.000e+064.79solute carrier family 11 member 1 [Source:NCBI gen... [more]
SLC11A10.000e+067.35solute carrier family 11 member 1 [Source:NCBI gen... [more]
rtn10.000e+065.00reticulon 1 [Source:Xenbase;Acc:XB-GENE-1011333][more]
rtn10.000e+064.73reticulon 1 [Source:Xenbase;Acc:XB-GENE-1011333][more]
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BLAST of slc11a-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Slc11a20.000e+066.59solute carrier family 11 (proton-coupled divalent ... [more]
Slc11a20.000e+066.59solute carrier family 11 (proton-coupled divalent ... [more]
Slc11a10.000e+060.78solute carrier family 11 (proton-coupled divalent ... [more]
Slc11a17.771e-15159.33solute carrier family 11 (proton-coupled divalent ... [more]
Slc11a26.886e-7660.82solute carrier family 11 (proton-coupled divalent ... [more]
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BLAST of slc11a-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P49282|NRAM2_MOUSE0.000e+066.59Natural resistance-associated macrophage protein 2... [more]
sp|P49283|MVL_DROME0.000e+064.38Protein Malvolio OS=Drosophila melanogaster OX=722... [more]
sp|O54902|NRAM2_RAT0.000e+065.73Natural resistance-associated macrophage protein 2... [more]
sp|P49281|NRAM2_HUMAN0.000e+066.16Natural resistance-associated macrophage protein 2... [more]
sp|P51027|NRAM1_CHICK0.000e+059.21Natural resistance-associated macrophage protein 1... [more]
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BLAST of slc11a-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YJ200.000e+0100.00Slc11a-1 OS=Schmidtea mediterranea OX=79327 GN=slc... [more]
R7VCE50.000e+071.25Uncharacterized protein OS=Capitella teleta OX=283... [more]
V4C5570.000e+068.89Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
A0A210PS890.000e+065.82Natural resistance-associated macrophage protein 2... [more]
Q4W8C50.000e+065.42Divalent metal transporter OS=Mizuhopecten yessoen... [more]
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BLAST of slc11a-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
slc11a20.000e+066.03natural resistance-associated macrophage protein 2... [more]
slc11a20.000e+066.03natural resistance-associated macrophage protein 2... [more]
slc11a20.000e+068.42natural resistance-associated macrophage protein 2... [more]
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BLAST of slc11a-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
SLC11A24.495e-13768.71solute carrier family 11 member 2 [Source:HGNC Sym... [more]
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BLAST of slc11a-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
SMF14.181e-4728.66Divalent metal ion transporter; broad specificity ... [more]
SMF38.804e-4531.65Putative divalent metal ion transporter involved i... [more]
SMF21.922e-4429.33Divalent metal ion transporter involved in mangane... [more]
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BLAST of slc11a-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO435580.000e+065.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of slc11a-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
slc11a20.000e+065.10natural resistance-associated macrophage protein 2... [more]
slc11a20.000e+065.10natural resistance-associated macrophage protein 2... [more]
ENSORLT00000020759.20.000e+061.89natural resistance-associated macrophage protein 2... [more]
ENSORLT00000027995.10.000e+061.89natural resistance-associated macrophage protein 2... [more]
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BLAST of slc11a-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000019511.12.684e-13799.54SMESG000019511.1[more]
SMESG000019511.11.769e-13699.53SMESG000019511.1[more]
SMESG000019504.11.524e-51100.00SMESG000019504.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30014808
GenBankAKN21474.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014808 ID=SMED30014808|Name=slc11a-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1885bp
TTAAATCCTTCCCAATTAACCTTGAAAAGCCAATTACATTTTGATTTATG
CTCTTTATATTTTAATAAAATTGTAAATAAATAGTATGAATAAAAATGAC
ATCAATGCTGAATCTTCAGCCATAGTCGAATCAAACTCAACTGCCGCGTC
AACATATTTCCAGGAAAGAGTTAATATACCTGATGATGATGAAGGAGTTG
ATGATCGTTCACATTTTAGCTTTAAAAAGTTATGGGCATTTACTGGACCG
GGATTTTTAATGAGTATTGCTTATTTAGATCCTGGGAATATTGAATCAGA
TTTACAAAGTGGTGCAATTGCTCAATTTAAGCTACTTTGGCTGTTGCTCT
TAGCTACTCTTCTTGGTTTAATGATGCAAAGATTGGCAGCAAGATTAGGT
GTGGTGACAGGGTTCCATTTGGCAGAGGTTTGTTATCAAAGATATCCCAA
GATACCAAGAATCATTCTTTGGGTTATGATTGAAATTGCAATTATTGGCT
CAGATATGCAAGAAGTCATTGGAACTGCTATTGCATTTAATTTATTAAGT
AATGGCGTGATACCTTTATGGGGTGGAGTTATTTTGACAATTATTGATAC
TTTTACGTTTCTCTTTCTGGATAAATATGGCTTGCGTAAATTGGAAGCGT
TTTTTGCAGTATTAATCACAACCATGGGATTCGCATTTGGTTATCAATAT
ATTGTTGTGAAACCAAATCAGGCGGAAGTTTTAAAAGGAATGTTTGTACC
GTATTGTGAAAATTGTGGCAGCAAAGAATTATTACAAGCTGTTGGGATCA
TTGGAGCGGTTATAATGCCTCACAATATTTATCTGCACTCTGCTCTAGTC
AAATCAAGGAACATCAACCGAAATATAAGAGCTAAAATTCGTGAAGCAAA
CTTTTATTACCTAATTGAATCAGGAGTCGCCCTTTTTATATCATTTTTGA
TTAACGTATTCGTTGTATCTGTATTTGCTGAAGGATTCTATGGAAAGAAC
ACCACGACAATAGTAGAAGAATGCAAGGCGAATAAAATTCCACATTGGGA
AGTTTTTAACAGTTCAGATGCGTTGGATGATATTGACATATACAAAGGAG
GAATTTTCCTCGGCTGTCGATTTGGATTAGCATGCCTATATATTTGGGCT
ATCGGTATTTTAGCGGCTGGTCAAAGCTCAACGATGACGGGCACATATGC
AGGCCAATTCGCAATGGAAGGCTTCCTCAATTTGACATGGAAACGTTGGC
AAAGAGTGTTACTGACTAGATCTATTGCAATCGCACCGACAATTTTCATT
GCTTTCTATCAAGGTATTCATAACCTGACTCACATGAATGATTTACTCAA
TGTTCTCATGAGTATGCAGCTGCCATTTGCAATTATTCCTATATTAACTT
TTACTTCTTCCAAACGAATGATGGCAGAATTTAAAAATGGAAGAATATCT
TCGTTATTAACAGTTTTCCTAGCATGTACGGTAATAGGAATCAACATTTA
CTTTGTCATAGTGTTTATTCAAACAAATGTTTCGAATTTTTGGGTTTATT
ATTTGCTCATTTCAATATTCTTGGCCCTTTACCTCCTGTTTATCGTGTAT
TTGTGTCTATATGGATTAGTAGAAAACAACAAATTACGGAAATTGATATT
AGGAAATTGTTGGAGACTTTTCGGAGACCTGATGATTTACAGGTCAATTA
ATGAAGTTTCTTAATTTCTATGAAGATAGTATTATAAGTTATGTTGACAG
ATTTTTAATTATTTTTTAAATACAAATTGAATATCAATTTTAAAAAACAT
TTTTATACAAAAATATTTGTTTCTGTCAATTTACAAAAGAGACTACGCTA
CTTTTTACCGATTTCTAAATAAAATCACGAAATGT
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protein sequence of SMED30014808-orf-1

>SMED30014808-orf-1 ID=SMED30014808-orf-1|Name=SMED30014808-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=543bp
MNKNDINAESSAIVESNSTAASTYFQERVNIPDDDEGVDDRSHFSFKKLW
AFTGPGFLMSIAYLDPGNIESDLQSGAIAQFKLLWLLLLATLLGLMMQRL
AARLGVVTGFHLAEVCYQRYPKIPRIILWVMIEIAIIGSDMQEVIGTAIA
FNLLSNGVIPLWGGVILTIIDTFTFLFLDKYGLRKLEAFFAVLITTMGFA
FGYQYIVVKPNQAEVLKGMFVPYCENCGSKELLQAVGIIGAVIMPHNIYL
HSALVKSRNINRNIRAKIREANFYYLIESGVALFISFLINVFVVSVFAEG
FYGKNTTTIVEECKANKIPHWEVFNSSDALDDIDIYKGGIFLGCRFGLAC
LYIWAIGILAAGQSSTMTGTYAGQFAMEGFLNLTWKRWQRVLLTRSIAIA
PTIFIAFYQGIHNLTHMNDLLNVLMSMQLPFAIIPILTFTSSKRMMAEFK
NGRISSLLTVFLACTVIGINIYFVIVFIQTNVSNFWVYYLLISIFLALYL
LFIVYLCLYGLVENNKLRKLILGNCWRLFGDLMIYRSINEVS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0030001metal ion transport
GO:0006810transport
GO:0015675nickel cation transport
GO:0015676vanadium ion transport
GO:0015684ferrous iron transport
GO:0015692lead ion transport
GO:0015992proton transport
GO:0034599cellular response to oxidative stress
GO:0034755iron ion transmembrane transport
GO:0035434copper ion transmembrane transport
GO:0035444nickel cation transmembrane transport
GO:0048813dendrite morphogenesis
GO:0048821erythrocyte development
GO:0055072iron ion homeostasis
GO:0060586multicellular organismal iron ion homeostasis
GO:0070574cadmium ion transmembrane transport
GO:0070627ferrous iron import
GO:0071421manganese ion transmembrane transport
GO:1902600hydrogen ion transmembrane transport
GO:1903874ferrous iron transmembrane transport
GO:0006778porphyrin-containing compound metabolic process
GO:0006779porphyrin-containing compound biosynthetic process
GO:0006783heme biosynthetic process
GO:0006811ion transport
GO:0006824cobalt ion transport
GO:0006825copper ion transport
GO:0006826iron ion transport
GO:0006828manganese ion transport
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007611learning or memory
GO:0010039response to iron ion
Vocabulary: molecular function
TermDefinition
GO:0046873metal ion transmembrane transporter activity
GO:0005215transporter activity
GO:0015094lead ion transmembrane transporter activity
GO:0015099nickel cation transmembrane transporter activity
GO:0015100vanadium ion transmembrane transporter activity
GO:0015295solute:proton symporter activity
GO:0015639ferrous iron uptake transmembrane transporter activity
GO:0022890inorganic cation transmembrane transporter activity
GO:0046870cadmium ion binding
GO:0046915transition metal ion transmembrane transporter activity
GO:0005375copper ion transmembrane transporter activity
GO:0005381iron ion transmembrane transporter activity
GO:0005384manganese ion transmembrane transporter activity
GO:0015078hydrogen ion transmembrane transporter activity
GO:0015086cadmium ion transmembrane transporter activity
GO:0015087cobalt ion transmembrane transporter activity
GO:0015093ferrous iron transmembrane transporter activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR001046NRAMP_fam
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0016324apical plasma membrane
GO:0031410cytoplasmic vesicle
GO:0031526brush border membrane
GO:0031902late endosome membrane
GO:0045177apical part of cell
GO:0045178basal part of cell
GO:0048471perinuclear region of cytoplasm
GO:0055037recycling endosome
GO:0070826paraferritin complex
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005739mitochondrion
GO:0005741mitochondrial outer membrane
GO:0005764lysosome
GO:0005765lysosomal membrane
GO:0005768endosome
GO:0005769early endosome
GO:0005770late endosome
GO:0005773vacuole
GO:0005802trans-Golgi network
GO:0005886plasma membrane
GO:0005887integral component of plasma membrane
GO:0005903brush border
GO:0009986cell surface
GO:0010008endosome membrane
GO:0012505endomembrane system
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001046NRAMP familyPRINTSPR00447NATRESASSCMPcoord: 128..154
score: 75.7
coord: 362..381
score: 83.8
coord: 183..204
score: 58.0
coord: 158..177
score: 64.0
coord: 390..407
score: 59.33
coord: 422..441
score: 68.2
coord: 235..258
score: 80.5
IPR001046NRAMP familyPFAMPF01566Nrampcoord: 69..452
e-value: 2.9E-118
score: 395.0
IPR001046NRAMP familyTIGRFAMTIGR01197TIGR01197coord: 47..446
e-value: 1.3E-171
score: 569.1
IPR001046NRAMP familyPANTHERPTHR11706SOLUTE CARRIER PROTEIN FAMILY 11 MEMBERcoord: 33..512
NoneNo IPR availablePANTHERPTHR11706:SF40NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2coord: 33..512
NoneNo IPR availableTMHMMTMhelixcoord: 186..208
NoneNo IPR availableTMHMMTMhelixcoord: 339..361
NoneNo IPR availableTMHMMTMhelixcoord: 454..476
NoneNo IPR availableTMHMMTMhelixcoord: 83..102
NoneNo IPR availableTMHMMTMhelixcoord: 486..508
NoneNo IPR availableTMHMMTMhelixcoord: 233..255
NoneNo IPR availableTMHMMTMhelixcoord: 420..442
NoneNo IPR availableTMHMMTMhelixcoord: 391..410
NoneNo IPR availableTMHMMTMhelixcoord: 157..179
NoneNo IPR availableTMHMMTMhelixcoord: 276..298