RRM domain-containing protein

Overview


Name	RRM domain-containing protein
Smed ID	SMED30014750
Length (bp)	1354

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of RRM domain-containing protein (SMED30014750) t-SNE clustered cells

Violin plots show distribution of expression levels for RRM domain-containing protein (SMED30014750) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RRM domain-containing protein (SMED30014750) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RRM domain-containing protein (SMED30014750) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30014750

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 14

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30014750	h1SMcG0010238	SmedASXL_016225	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
X1 cell	SMED30014750	h1SMcG0010238	SmedASXL_004848	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30014750	h1SMcG0010238	SmedASXL_004848	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30014750	h1SMcG0010238	dd_Smed_v4_1760_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30014750	h1SMcG0010238	dd_Smed_v4_1760_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30014750	h1SMcG0010238	dd_Smed_v4_1760_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30014750	h1SMcG0010238	dd_Smed_v4_1760_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30014750	h1SMcG0010238	dd_Smed_v4_1760_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30014750	h1SMcG0010238	dd_Smed_v4_13812_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30014750	h1SMcG0010238	dd_Smed_v4_13812_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30014750	h1SMcG0010238	dd_Smed_v4_13812_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30014750	h1SMcG0010238	dd_Smed_v6_13812_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30014750	h1SMcG0010238	dd_Smed_v6_22819_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30014750	h1SMcG0010238	OX_Smed_1.0.12332	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2A (transformer 2 alpha homolog [Source:HGNC Symbol;Acc:HGNC:16645])

HSP 1 Score: 80.8777 bits (198), Expect = 3.394e-17
Identity = 37/92 (40.22%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:    9 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAH 100

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2A (transformer 2 alpha homolog [Source:HGNC Symbol;Acc:HGNC:16645])

HSP 1 Score: 80.8777 bits (198), Expect = 3.471e-17
Identity = 37/92 (40.22%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:    9 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAH 100

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2A (transformer 2 alpha homolog [Source:HGNC Symbol;Acc:HGNC:16645])

HSP 1 Score: 80.8777 bits (198), Expect = 3.471e-17
Identity = 37/92 (40.22%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:    9 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAH 100

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2A (transformer 2 alpha homolog [Source:HGNC Symbol;Acc:HGNC:16645])

HSP 1 Score: 81.6481 bits (200), Expect = 1.249e-16
Identity = 37/92 (40.22%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:  110 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAH 201

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Human
Match: TRA2B (transformer 2 beta homolog [Source:HGNC Symbol;Acc:HGNC:10781])

HSP 1 Score: 76.2554 bits (186), Expect = 1.682e-15
Identity = 36/92 (39.13%), Postives = 59/92 (64.13%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G R    P+  +G+FGLS  TTE  L ++F KYG I  + +V ++++  SRG++F+ +E++D A +A +   G  +DGR IR+D+S  KR +
Sbjct:    9 GNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPH 100

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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: rsp-8 (SR Protein (Splicing factor) [Source:UniProtKB/TrEMBL;Acc:G3MU77])

HSP 1 Score: 71.2478 bits (173), Expect = 1.631e-13
Identity = 35/90 (38.89%), Postives = 54/90 (60.00%), Query Frame = 2

Query:  485 RDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            R+  +PS  +G+F LS  TTE  L  +F ++G+IN   LV +R +G SRG+ FI +  I+ A  A  +     +DG +IR+D+S  KR +
Sbjct:   69 RENPQPSKCLGVFNLSSYTTEKDLRDVFGEFGEINKCDLVYDRPSGNSRGFGFIYFNLIEDATAARDKLCNTDLDGHKIRVDFSLTKRGH 158

[Close]

Query:  485 RDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            R+  +PS  +G+F LS  TTE  L  +F ++G+IN   LV +R +G SRG+ FI +  I+ A  A  +     +DG +IR+D+S  KR +
Sbjct:   69 RENPQPSKCLGVFNLSSYTTEKDLRDVFGEFGEINKCDLVYDRPSGNSRGFGFIYFNLIEDATAARDKLCNTDLDGHKIRVDFSLTKRGH 158

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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: cpf-2 (Cleavage and Polyadenylation Factor [Source:UniProtKB/TrEMBL;Acc:O45577])

HSP 1 Score: 66.6254 bits (161), Expect = 7.473e-12
Identity = 32/86 (37.21%), Postives = 52/86 (60.47%), Query Frame = 2

Query:  509 TVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNG 766
            +V +  +S   +ED +  IF K G + S+K+V +RETG+ +GY FIE+ DI +A  A++   G  + GR +R+D + G  N +  G
Sbjct:   19 SVFVGNISYDVSEDTIRSIFSKAGNVLSIKMVHDRETGKPKGYGFIEFPDIQTAEVAIRNLNGYELSGRILRVDSAAGGMNMEEFG 104

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Query:  509 TVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNG 766
            +V +  +S   +ED +  IF K G + S+K+V +RETG+ +GY FIE+ DI +A  A++   G  + GR +R+D + G  N +  G
Sbjct:   19 SVFVGNISYDVSEDTIRSIFSKAGNVLSIKMVHDRETGKPKGYGFIEFPDIQTAEVAIRNLNGYELSGRILRVDSAAGGMNMEEFG 104

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BLAST of RRM domain-containing protein vs. Ensembl Celegans
Match: rbm-3.1 (RNA Binding Motif protein homolog [Source:UniProtKB/TrEMBL;Acc:O45712])

HSP 1 Score: 55.8398 bits (133), Expect = 6.634e-10
Identity = 25/67 (37.31%), Postives = 46/67 (68.66%), Query Frame = 2

Query:  536 KTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYS 736
            +TTE+ L   F   G+IN++++V +RETG  RG++FIE+ +  SA +A+++  G   +GR +R++ +
Sbjct:   15 QTTEEELGNFFSSIGQINNVRIVCDRETGRPRGFAFIEFAEEGSAQRAVEQMNGAEFNGRPLRVNLA 81

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BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089616)

HSP 1 Score: 77.0258 bits (188), Expect = 2.810e-16
Identity = 33/91 (36.26%), Postives = 59/91 (64.84%), Query Frame = 2

Query:  482 TRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            +R++ + S  +G+FGL+  T++  + ++F+KYG I  +++V++ +T  SRG+ FI +E +  A  A   C G  VDGR IR+D+S  +R +
Sbjct:    4 SREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAH 94

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089615)

HSP 1 Score: 77.411 bits (189), Expect = 6.698e-16
Identity = 33/91 (36.26%), Postives = 59/91 (64.84%), Query Frame = 2

Query:  482 TRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            +R++ + S  +G+FGL+  T++  + ++F+KYG I  +++V++ +T  SRG+ FI +E +  A  A   C G  VDGR IR+D+S  +R +
Sbjct:   51 SREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAH 141

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089619)

HSP 1 Score: 77.411 bits (189), Expect = 6.698e-16
Identity = 33/91 (36.26%), Postives = 59/91 (64.84%), Query Frame = 2

Query:  482 TRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            +R++ + S  +G+FGL+  T++  + ++F+KYG I  +++V++ +T  SRG+ FI +E +  A  A   C G  VDGR IR+D+S  +R +
Sbjct:   51 SREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAH 141

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089620)

HSP 1 Score: 77.411 bits (189), Expect = 1.097e-15
Identity = 33/91 (36.26%), Postives = 59/91 (64.84%), Query Frame = 2

Query:  482 TRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            +R++ + S  +G+FGL+  T++  + ++F+KYG I  +++V++ +T  SRG+ FI +E +  A  A   C G  VDGR IR+D+S  +R +
Sbjct:   89 SREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAH 179

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Match: tra2 (gene:FBgn0003742 transcript:FBtr0089621)

HSP 1 Score: 77.411 bits (189), Expect = 1.097e-15
Identity = 33/91 (36.26%), Postives = 59/91 (64.84%), Query Frame = 2

Query:  482 TRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            +R++ + S  +G+FGL+  T++  + ++F+KYG I  +++V++ +T  SRG+ FI +E +  A  A   C G  VDGR IR+D+S  +R +
Sbjct:   89 SREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAH 179

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 80.8777 bits (198), Expect = 3.332e-17
Identity = 36/85 (42.35%), Postives = 57/85 (67.06%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            P+  +G+FGLS  TTE  L ++F +YG +  + +V ++ TG SRG++F+ +E ID A +A++   G  +DGR IR+DYS  KR +
Sbjct:  104 PNTCLGVFGLSLYTTERDLREVFSRYGSLAGVNVVYDQRTGRSRGFAFVYFEHIDDAKEAMERANGMELDGRRIRVDYSITKRPH 188

[Close]

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            P+  +G+FGLS  TTE  L ++F +YG +  + +V ++ TG SRG++F+ +E ID A +A++   G  +DGR IR+DYS  KR +
Sbjct:  104 PNTCLGVFGLSLYTTERDLREVFSRYGSLAGVNVVYDQRTGRSRGFAFVYFEHIDDAKEAMERANGMELDGRRIRVDYSITKRPH 188

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 81.6481 bits (200), Expect = 9.557e-17
Identity = 36/85 (42.35%), Postives = 57/85 (67.06%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            P+  +G+FGLS  TTE  L ++F +YG +  + +V ++ TG SRG++F+ +E ID A +A++   G  +DGR IR+DYS  KR +
Sbjct:  133 PNTCLGVFGLSLYTTERDLREVFSRYGSLAGVNVVYDQRTGRSRGFAFVYFEHIDDAKEAMERANGMELDGRRIRVDYSITKRPH 217

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 81.2629 bits (199), Expect = 1.272e-16
Identity = 36/85 (42.35%), Postives = 57/85 (67.06%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            P+  +G+FGLS  TTE  L ++F +YG +  + +V ++ TG SRG++F+ +E ID A +A++   G  +DGR IR+DYS  KR +
Sbjct:  133 PNTCLGVFGLSLYTTERDLREVFSRYGSLAGVNVVYDQRTGRSRGFAFVYFEHIDDAKEAMERANGMELDGRRIRVDYSITKRPH 217

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Match: cirbpa (cold inducible RNA binding protein a [Source:ZFIN;Acc:ZDB-GENE-050417-329])

HSP 1 Score: 70.4774 bits (171), Expect = 9.175e-14
Identity = 36/71 (50.70%), Postives = 46/71 (64.79%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            I GLS  TTE +L   F KYG I ++ +  NRET  SRG+ F+ +E+ D A  AL+   GKSVDGR IR+D
Sbjct:    9 IGGLSFDTTEQSLEDAFSKYGVITNVHVARNRETNRSRGFGFVTFENPDDAKDALEGMNGKSVDGRTIRVD 79

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: plekhg5 (pleckstrin homology and RhoGEF domain containing G5 [Source:Xenbase;Acc:XB-GENE-6039487])

HSP 1 Score: 79.7221 bits (195), Expect = 4.609e-16
Identity = 36/92 (39.13%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E I+ + +A++   G  +DGR IR+DYS  KR +
Sbjct:  105 GSRANPDPNICIGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIEDSREAMEHANGMELDGRRIRVDYSITKRAH 196

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: rit1 (Ras-like without CAAX 1 [Source:Xenbase;Acc:XB-GENE-5777077])

HSP 1 Score: 78.5666 bits (192), Expect = 2.004e-15
Identity = 37/92 (40.22%), Postives = 60/92 (65.22%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G R    P+  +G+FGLS  TTE  L ++F KYG I+ + +V ++++  SRG+SF+ +E++D A +A +   G  +DGR IR+D+S  KR +
Sbjct:  144 GNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPISDVSIVYDQQSRRSRGFSFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPH 235

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: cirbp (cold inducible RNA binding protein [Source:NCBI gene;Acc:549982])

HSP 1 Score: 67.781 bits (164), Expect = 1.129e-12
Identity = 30/71 (42.25%), Postives = 51/71 (71.83%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            + GL+ +TTE++L ++F KYG++  + +V +RE+  SRG+ F+ +E+ + A  A+    GKSVDGR+IR+D
Sbjct:   10 VGGLNFETTEESLEQVFSKYGQVAEVVVVKDRESKRSRGFGFVTFENPEDAKDAMMAMNGKSVDGRQIRVD 80

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: cirbp (cold inducible RNA binding protein [Source:NCBI gene;Acc:549982])

HSP 1 Score: 67.0106 bits (162), Expect = 2.061e-12
Identity = 30/71 (42.25%), Postives = 51/71 (71.83%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            + GL+ +TTE++L ++F KYG++  + +V +RE+  SRG+ F+ +E+ + A  A+    GKSVDGR+IR+D
Sbjct:   22 VGGLNFETTEESLEQVFSKYGQVAEVVVVKDRESKRSRGFGFVTFENPEDAKDAMMAMNGKSVDGRQIRVD 92

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Match: cirbp (cold inducible RNA binding protein [Source:NCBI gene;Acc:549982])

HSP 1 Score: 66.6254 bits (161), Expect = 2.263e-12
Identity = 30/71 (42.25%), Postives = 51/71 (71.83%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            + GL+ +TTE++L ++F KYG++  + +V +RE+  SRG+ F+ +E+ + A  A+    GKSVDGR+IR+D
Sbjct:   22 VGGLNFETTEESLEQVFSKYGQVAEVVVVKDRESKRSRGFGFVTFENPEDAKDAMMAMNGKSVDGRQIRVD 92

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Tra2a (transformer 2 alpha [Source:MGI Symbol;Acc:MGI:1933972])

HSP 1 Score: 81.6481 bits (200), Expect = 8.333e-17
Identity = 37/92 (40.22%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:  108 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAH 199

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Tra2a (transformer 2 alpha [Source:MGI Symbol;Acc:MGI:1933972])

HSP 1 Score: 81.6481 bits (200), Expect = 8.574e-17
Identity = 37/92 (40.22%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:  108 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAH 199

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Cirbp (cold inducible RNA binding protein [Source:MGI Symbol;Acc:MGI:893588])

HSP 1 Score: 74.7146 bits (182), Expect = 5.430e-16
Identity = 35/73 (47.95%), Postives = 51/73 (69.86%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYS 736
            + GLS  T E AL ++F KYG+I+ + +V +RET  SRG+ F+ +E+ID A  A+    GKSVDGR+IR+D +
Sbjct:   10 VGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQA 82

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Cirbp (cold inducible RNA binding protein [Source:MGI Symbol;Acc:MGI:893588])

HSP 1 Score: 75.8702 bits (185), Expect = 1.146e-15
Identity = 35/71 (49.30%), Postives = 50/71 (70.42%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            + GLS  T E AL ++F KYG+I+ + +V +RET  SRG+ F+ +E+ID A  A+    GKSVDGR+IR+D
Sbjct:   10 VGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVD 80

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Match: Tra2b (transformer 2 beta [Source:MGI Symbol;Acc:MGI:106016])

HSP 1 Score: 76.2554 bits (186), Expect = 1.154e-15
Identity = 36/92 (39.13%), Postives = 59/92 (64.13%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G R    P+  +G+FGLS  TTE  L ++F KYG I  + +V ++++  SRG++F+ +E++D A +A +   G  +DGR IR+D+S  KR +
Sbjct:    9 GNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERANGMELDGRRIRVDFSITKRPH 100

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6PFR5|TRA2A_MOUSE (Transformer-2 protein homolog alpha OS=Mus musculus OX=10090 GN=Tra2a PE=1 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 5.913e-16
Identity = 37/92 (40.22%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:  108 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAH 199

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q13595|TRA2A_HUMAN (Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 5.998e-16
Identity = 37/92 (40.22%), Postives = 61/92 (66.30%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG ++ + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:  110 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAH 201

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|O02008|TRA2_DROVI (Transformer-2 sex-determining protein OS=Drosophila virilis OX=7244 GN=tra2 PE=3 SV=1)

HSP 1 Score: 80.4925 bits (197), Expect = 1.229e-15
Identity = 35/91 (38.46%), Postives = 58/91 (63.74%), Query Frame = 2

Query:  482 TRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
             RD+ + S  +G+FGL+  TT+  + ++F+K+G I  +++V++  T  SRG+ FI +E++  A  A   C G  VDGR IR+DYS  +R +
Sbjct:   97 ARDHPQASRCIGVFGLNTNTTQQKVRELFNKFGPIERIQMVIDAHTHRSRGFCFIYFENLGDARVAKDACTGMEVDGRRIRVDYSITQRAH 187

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|P60825|CIRBP_RAT (Cold-inducible RNA-binding protein OS=Rattus norvegicus OX=10116 GN=Cirbp PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 8.016e-15
Identity = 35/71 (49.30%), Postives = 50/71 (70.42%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            + GLS  T E AL ++F KYG+I+ + +V +RET  SRG+ F+ +E+ID A  A+    GKSVDGR+IR+D
Sbjct:   10 VGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVD 80

[Close]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Match: sp|P60824|CIRBP_MOUSE (Cold-inducible RNA-binding protein OS=Mus musculus OX=10090 GN=Cirbp PE=1 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 8.016e-15
Identity = 35/71 (49.30%), Postives = 50/71 (70.42%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            + GLS  T E AL ++F KYG+I+ + +V +RET  SRG+ F+ +E+ID A  A+    GKSVDGR+IR+D
Sbjct:   10 VGGLSFDTNEQALEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVD 80

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A1S6KMI2 (RRM domain-containing protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 304.679 bits (779), Expect = 5.009e-98
Identity = 252/252 (100.00%), Postives = 252/252 (100.00%), Query Frame = 2

Query:   44 MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPXXXXXXXXXXXXXXXXXXXXXXXXXXHVIAKKSYREDKPSYRDERKPFXXXXXXXXXXXXXXXXXXXXXXXXXXXFKEDRGRNDDRHXXXXXXXXXXXXXXXXXXXXXXXXXGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY 799
            MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPKIDKKASKRRSISKDSRSRSISRNRKHVIAKKSYREDKPSYRDERKPFREERRSARDDRDSYRNDRDSYRNDRRSFKEDRGRNDDRHSNRYERSGRRNRSRSRSPEFSRYSRGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY
Sbjct:    1 MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPKIDKKASKRRSISKDSRSRSISRNRKHVIAKKSYREDKPSYRDERKPFREERRSARDDRDSYRNDRDSYRNDRRSFKEDRGRNDDRHSNRYERSGRRNRSRSRSPEFSRYSRGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY 252

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A3R7LVI2 (Transformer-2 protein OS=Penaeus vannamei OX=6689 GN=C7M84_017849 PE=4 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 6.271e-20
Identity = 43/92 (46.74%), Postives = 65/92 (70.65%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            GTRD  +PS  +G+FGLS  TTE  L+ IFDK+G +  +++V++ +TG+SRG++F+ +E +  A +A  EC G  +DGR IR+DYS  KR +
Sbjct:   73 GTRDNPEPSKCLGVFGLSVHTTERQLYTIFDKFGPLEKVQVVLDSKTGKSRGFAFVYFESLKDASEAKNECSGMEIDGRRIRVDYSITKRPH 164

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: C0IRC8 (Transformer-2 protein OS=Penaeus monodon OX=6687 PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 9.348e-20
Identity = 43/92 (46.74%), Postives = 65/92 (70.65%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            GTRD  +PS  +G+FGLS  TTE  L+ IFDK+G +  +++V++ +TG+SRG++F+ +E +  A +A  EC G  +DGR IR+DYS  KR +
Sbjct:   99 GTRDNPEPSKCLGVFGLSVHTTERQLYTIFDKFGPLEKVQVVLDSKTGKSRGFAFVYFESLKDASEAKNECSGMEIDGRRIRVDYSITKRPH 190

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: C0IRC9 (Variant transformer-2 protein OS=Penaeus monodon OX=6687 PE=2 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 9.828e-20
Identity = 43/92 (46.74%), Postives = 65/92 (70.65%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            GTRD  +PS  +G+FGLS  TTE  L+ IFDK+G +  +++V++ +TG+SRG++F+ +E +  A +A  EC G  +DGR IR+DYS  KR +
Sbjct:   94 GTRDNPEPSKCLGVFGLSVHTTERQLYTIFDKFGPLEKVQVVLDSKTGKSRGFAFVYFESLKDASEAKNECSGMEIDGRRIRVDYSITKRPH 185

[Close]

BLAST of RRM domain-containing protein vs. TrEMBL
Match: A0A3R7QGW1 (Transformer-2c OS=Penaeus vannamei OX=6689 GN=C7M84_014972 PE=4 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 1.951e-19
Identity = 43/92 (46.74%), Postives = 64/92 (69.57%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R+   PSN +GIFGLS  TTE  L  +F KYG IN +++V++ +TG SRG++FI ++ +D A +A  +C G  +DGR IR+DYS  +R +
Sbjct:   93 GSREDPSPSNCLGIFGLSLYTTERQLHHLFGKYGHINEVQVVLDAKTGRSRGFAFIYFDHVDDATEAKDQCTGMEIDGRRIRVDYSITERAH 184

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 80.8777 bits (198), Expect = 6.584e-17
Identity = 37/92 (40.22%), Postives = 60/92 (65.22%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    P+  +G+FGLS  TTE  L ++F +YG +  + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:   98 GSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLAGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRPH 189

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 79.337 bits (194), Expect = 1.718e-16
Identity = 35/85 (41.18%), Postives = 57/85 (67.06%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            P+  +G+FGLS  TTE  L ++F +YG +  + +V ++ TG SRG++F+ +E ID + +A++   G  +DGR IR+DYS  KR +
Sbjct:  133 PNTCLGVFGLSLYTTERDLREVFSRYGPLAGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRPH 217

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000034164.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:6544829:6548035:1 gene:ENSAMXG00000039469.1 transcript:ENSAMXT00000034164.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.0182 bits (175), Expect = 1.864e-14
Identity = 34/90 (37.78%), Postives = 59/90 (65.56%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKR 748
            G R    P+  +G+FGLS  TTE  L ++F KYG ++S+ +V ++++  SRG++F+ +E+ + + +A +   G  +DGR IR+DYS  +R
Sbjct:    9 GNRANPDPNCCLGVFGLSLYTTERDLREVFSKYGPLSSVSIVYDQQSRRSRGFAFVYFENREDSREAKERANGMELDGRRIRVDYSITQR 98

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: cirbpa (cold inducible RNA binding protein a [Source:ZFIN;Acc:ZDB-GENE-050417-329])

HSP 1 Score: 70.4774 bits (171), Expect = 4.920e-14
Identity = 36/71 (50.70%), Postives = 47/71 (66.20%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            I GLS  TTE +L + F KYG I ++ +  NRET  SRG+ F+ +E+ D A  AL+   GKSVDGR IR+D
Sbjct:    9 IGGLSFDTTEQSLEEAFSKYGVITNVHVARNRETNRSRGFGFVTFENPDDAKDALEGMNGKSVDGRAIRVD 79

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Match: tra2b (transformer-2 protein homolog alpha-like [Source:NCBI gene;Acc:103029311])

HSP 1 Score: 69.707 bits (169), Expect = 6.998e-13
Identity = 33/92 (35.87%), Postives = 58/92 (63.04%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G R    P+  +G+FGLS  TTE  L ++F KYG +  + +V ++++  SRG++F+ +E+ + + +A +   G  +DGR IR+D+S  KR +
Sbjct:  109 GNRANPDPTCCLGVFGLSLYTTERDLREVFSKYGPLADVCIVYDQQSRRSRGFAFVYFENREDSQEAKERANGMELDGRRIRVDFSITKRPH 200

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: tra2a (transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1391])

HSP 1 Score: 74.3294 bits (181), Expect = 3.015e-15
Identity = 34/92 (36.96%), Postives = 60/92 (65.22%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G+R    PS  +G+FGLS  T E  L ++F +YG + S+ +V ++++G SRG++F+ +++ + A +A +   G  +DGR IR+D+S  KR +
Sbjct:  103 GSRVNPDPSCCLGVFGLSLHTGEKDLKEVFSRYGPVQSVNVVYDQQSGRSRGFAFVYFDNSEDAKEAKERANGMELDGRYIRVDFSITKRAH 194

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: tra2b (transformer 2 beta homolog [Source:ZFIN;Acc:ZDB-GENE-040426-1094])

HSP 1 Score: 71.633 bits (174), Expect = 3.410e-14
Identity = 31/92 (33.70%), Postives = 59/92 (64.13%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G R   +P+  +G+FGLS  TTE  L ++F +YG +  + +V ++++G  RG++F+  ++++ + +A +   G  +DGR IR+D+S  KR +
Sbjct:   97 GDRGNPEPNTCLGVFGLSLYTTEHDLREVFGRYGPVADVNVVYDQQSGRPRGFAFVYMQNMEDSKEAKERVNGMELDGRNIRVDFSITKRAH 188

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: rbmx (RNA binding motif protein X-linked [Source:NCBI gene;Acc:321860])

HSP 1 Score: 64.3142 bits (155), Expect = 1.718e-11
Identity = 29/71 (40.85%), Postives = 47/71 (66.20%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            I GLS  T E+AL  IF KYG++  + ++ +RET  SRG++F+ + + D A  A ++  GK +DGR I+++
Sbjct:   11 IGGLSTDTNENALETIFSKYGRVAEVLIMKDRETNRSRGFAFVTFANPDDAKGAERDMNGKPLDGRNIKVE 81

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: rbmx (RNA binding motif protein X-linked [Source:NCBI gene;Acc:321860])

HSP 1 Score: 61.6178 bits (148), Expect = 1.366e-10
Identity = 32/91 (35.16%), Postives = 53/91 (58.24%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSR 790
            + GL+  TTE AL   F KYG++  + L+ +RET  SRG++F+ + + + A +A ++  GK ++GR +R+D +         G  RY  SR
Sbjct:   11 VGGLNIDTTEKALEATFSKYGRVADVLLMKDRETNLSRGFAFVTFANPEDAKEAERDANGKVLEGRAMRVDQATKPSFESFPGGGRYGFSR 101

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Match: ncl (nucleolin [Source:ZFIN;Acc:ZDB-GENE-030131-6986])

HSP 1 Score: 61.6178 bits (148), Expect = 2.101e-10
Identity = 29/78 (37.18%), Postives = 51/78 (65.38%), Query Frame = 2

Query:  503 SNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYS 736
            SNT+ +  LS +  ED+L  +F+      +++++M+RETG+ RG +F+++  ID A  A+K   G  V+GR IR+++S
Sbjct:  458 SNTLMVRNLSFQADEDSLRSVFENA---EAVRVLMDRETGKPRGMAFVDFASIDDAKAAMKAHSGAEVEGRAIRLEFS 532

HSP 2 Score: 57.7658 bits (138), Expect = 2.830e-9
Identity = 28/89 (31.46%), Postives = 53/89 (59.55%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGK 745
            GT    + S+T+ + GL   T+ED L    D +    + ++V +R++G+S+GY+++++   D A  AL   +G  +DG +I +D++R K
Sbjct:  536 GTPGPSEASSTLFVRGLGEDTSEDTL---MDSFEGATAARIVTDRDSGQSKGYAYVDFSSADEAKSALNAMKGVEIDGSQIYVDFARPK 621

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: NSR1 (Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by polyphosphorylation [Source:SGD;Acc:S000003391])

HSP 1 Score: 61.2326 bits (147), Expect = 1.016e-10
Identity = 24/84 (28.57%), Postives = 56/84 (66.67%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRN 751
            PS+T+ +  LS     DA++++F K+G++ S+++  + ET + +G+ ++++ +++ A +AL   +G+ +D R +R+D+S  + N
Sbjct:  265 PSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNRPVRLDFSSPRPN 348

HSP 2 Score: 48.9062 bits (115), Expect = 9.058e-7
Identity = 28/86 (32.56%), Postives = 50/86 (58.14%), Query Frame = 2

Query:  488 DYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGK 745
            + E+P+ T+ +  LS    ++ L K F+  G +   +++  R T  SRGY ++++E+   A +A++E +GK +DGR I  D S  K
Sbjct:  163 ETEEPA-TIFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCDMSTSK 247

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: IST3 (Component of the U2 snRNP; required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing; diploid mutants have a specific defect in MATa1 pre-mRNA splicing which leads to haploid gene expression in diploids [Source:SGD;Acc:S000001444])

HSP 1 Score: 51.6026 bits (122), Expect = 1.435e-8
Identity = 28/84 (33.33%), Postives = 50/84 (59.52%), Query Frame = 2

Query:  512 VGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYS--RGKRNYQ 757
            + I  L+R+ TE  +  +F +YG    + L  +  TGES+G+++++YED  S I A+    G  + GR +++D++  R KR+ Q
Sbjct:   33 IYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQ 116

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: NAM8 (RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function [Source:SGD;Acc:S000001128])

HSP 1 Score: 51.9878 bits (123), Expect = 1.072e-7
Identity = 31/100 (31.00%), Postives = 58/100 (58.00%), Query Frame = 2

Query:  497 KPSNTVGIFG--LSRKTTEDALWKIF-DKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRS 787
            K  N   IF   L+   TE  L+++F ++Y   +  K+V ++ TG S+GY F+++ + D    AL E +G  ++GR I++  + G++ +  +G+  Y+RS
Sbjct:  158 KSGNNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRAIKVGPTSGQQQHV-SGNNDYNRS 256

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: RIE1 (Putative RNA binding protein; localizes to stress granules induced by glucose deprivation; interacts with Rbg1p in a two-hybrid assay; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003482])

HSP 1 Score: 51.9878 bits (123), Expect = 1.318e-7
Identity = 26/78 (33.33%), Postives = 44/78 (56.41%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDY 733
            P N + + G+++  +   L  +F KYG I S+KL+ ++  GE  GY FI Y     A   +KE  G++V+G  + ++Y
Sbjct:  194 PGN-IFVGGIAKSLSIGELSFLFSKYGPILSMKLIYDKTKGEPNGYGFISYPLGSQASLCIKELNGRTVNGSTLFINY 270

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Match: HRP1 (Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483])

HSP 1 Score: 50.447 bits (119), Expect = 3.145e-7
Identity = 28/79 (35.44%), Postives = 43/79 (54.43%), Query Frame = 2

Query:  488 DYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYE---DIDSAIQALKECRGKSVDGR 715
            D  K S  + I GL+  TTED L + F KYG +  LK++ +  TG SRG+ F+ +E    +D  ++      GK +D +
Sbjct:  153 DLSKESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKTQHILDGKVIDPK 231

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO44802 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUS7])

HSP 1 Score: 84.7297 bits (208), Expect = 3.140e-19
Identity = 41/92 (44.57%), Postives = 58/92 (63.04%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G RD   PS  +G+FGLS  TTE  L  +F+KYG + ++++V + +TG SRG+ F+ YED   A  A +   G  +DGR IR+DYS  KR +
Sbjct:   86 GNRDNPSPSRCLGVFGLSLYTTERDLRPVFEKYGPVEAIQIVYDHQTGRSRGFGFVYYEDTKDAEVAKERTTGIELDGRRIRVDYSVTKRAH 177

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO38445 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCR4])

HSP 1 Score: 68.9366 bits (167), Expect = 1.752e-12
Identity = 30/83 (36.14%), Postives = 56/83 (67.47%), Query Frame = 2

Query:  488 DYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYS 736
            D   P++++ +  LS  TT D+L   F+     ++ K++ +RE+GESRG+ F++Y+D+++A + L E  G  VDGR++R+D++
Sbjct:  471 DQNPPNSSLIVRNLSYDTTTDSLGAAFEG---CSNAKVIFDRESGESRGFGFVDYDDVETAKKVLSEMAGAEVDGRQVRLDFA 550

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO42298 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1T6])

HSP 1 Score: 55.0694 bits (131), Expect = 1.206e-8
Identity = 28/79 (35.44%), Postives = 50/79 (63.29%), Query Frame = 2

Query:  509 TVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGK 745
            T+ I  LS++T  + L + F KYG++ + +LV +  TG SRGY+F+E+++   A  A +E     +DG+EI +++  G+
Sbjct:   55 TLFIGRLSKETRAETLVEAFSKYGEVENCRLVRDFVTGFSRGYAFVEFKERWDAKTAYREISKCCIDGQEILVEFEAGR 133

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO45916 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRA7])

HSP 1 Score: 54.6842 bits (130), Expect = 3.856e-8
Identity = 27/78 (34.62%), Postives = 48/78 (61.54%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECR--GKSVDGREIRM 727
            P + V +  L+R T    L + F  +G+I  L++V + ETG SRG++FI + + +SA +A++ C+     +DGR+I +
Sbjct:   60 PRSKVFVGNLNRDTKPVTLAEYFSVFGEIEGLRIVKDHETGISRGFAFITFTEPESASKAIRWCKHHHPQLDGRQITI 137

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Match: EDO36859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHB5])

HSP 1 Score: 53.5286 bits (127), Expect = 4.581e-8
Identity = 29/79 (36.71%), Postives = 43/79 (54.43%), Query Frame = 2

Query:  509 TVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGK 745
            T+ I  ++  T+E  L +  + YG I  + +V N +  + RGY+FIEYE       A K   GK +DGR I +D  RG+
Sbjct:  104 TLFIGRINYDTSESKLRREMEMYGPIKHISMVYNSKASKPRGYAFIEYEHERDMHAAYKHADGKKIDGRRIVVDVERGR 182

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: tra2a (transformer-2 protein homolog alpha [Source:NCBI gene;Acc:101157868])

HSP 1 Score: 86.2705 bits (212), Expect = 1.368e-18
Identity = 38/92 (41.30%), Postives = 63/92 (68.48%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            GTR+   PS  +G+FGL+  TTE  L ++F +YG++  + +V ++ TG SRG++FI +E +  A +A++   G ++DGR+IR+DYS  KR +
Sbjct:  100 GTRENPDPSTCLGVFGLNLSTTERDLREVFSRYGRLTGINMVHDQRTGRSRGFAFIYFERLCDAREAIEHTNGMNMDGRQIRVDYSITKRPH 191

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: tra2a (transformer 2a [Source:NCBI gene;Acc:100049284])

HSP 1 Score: 73.559 bits (179), Expect = 2.941e-14
Identity = 34/92 (36.96%), Postives = 60/92 (65.22%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G R    PS  +G+FGLS  TTE  L ++F KYG ++ + +V ++++  SRG++F+ +E+ + + +A ++  G  +DGR IR+D+S  KR +
Sbjct:  106 GNRGNPDPSCCLGVFGLSLYTTERDLREVFSKYGPLSEVNIVYDQQSRRSRGFAFVYFENSEDSKEAKEQANGMELDGRRIRVDFSITKRAH 197

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: cirbpa (cold inducible RNA binding protein [Source:NCBI gene;Acc:101165004])

HSP 1 Score: 70.8626 bits (172), Expect = 4.359e-14
Identity = 32/71 (45.07%), Postives = 49/71 (69.01%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            I GLS +T ED+L   F KYG I  + ++ ++ETG SRG+ F++Y++++ A  AL    GK++DGR IR+D
Sbjct:    9 IGGLSFETNEDSLAAAFGKYGTIEKVDVIRDKETGRSRGFGFVKYDNVEDAKDALDAMNGKTLDGRAIRVD 79

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: cirbpa (cold inducible RNA binding protein [Source:NCBI gene;Acc:101165004])

HSP 1 Score: 70.0922 bits (170), Expect = 6.465e-14
Identity = 32/71 (45.07%), Postives = 49/71 (69.01%), Query Frame = 2

Query:  518 IFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMD 730
            I GLS +T ED+L   F KYG I  + ++ ++ETG SRG+ F++Y++++ A  AL    GK++DGR IR+D
Sbjct:    8 IGGLSFETNEDSLAAAFGKYGTIEKVDVIRDKETGRSRGFGFVKYDNVEDAKDALDAMNGKTLDGRAIRVD 78

[Close]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Match: tra2b (transformer 2 beta homolog [Source:NCBI gene;Acc:100049285])

HSP 1 Score: 72.0182 bits (175), Expect = 1.043e-13
Identity = 34/92 (36.96%), Postives = 57/92 (61.96%), Query Frame = 2

Query:  479 GTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            G R    P+  +G+FGLS  TTE  L  +F KYG +  + +V ++++  SRG++F+ +E+   A +A ++  G  +DGR IR+D+S  KR +
Sbjct:  113 GNRANPDPNACLGVFGLSLYTTERDLKDVFSKYGPLADVSIVYDQQSRRSRGFAFVYFENTPDAKEAKEKANGMELDGRRIRVDFSITKRPH 204

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000063924.1 (SMESG000063924.1)

HSP 1 Score: 304.679 bits (779), Expect = 1.350e-101
Identity = 252/252 (100.00%), Postives = 252/252 (100.00%), Query Frame = 2

Query:   44 MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPXXXXXXXXXXXXXXXXXXXXXXXXXXHVIAKKSYREDKPSYRDERKPFXXXXXXXXXXXXXXXXXXXXXXXXXXXFKEDRGRNDDRHXXXXXXXXXXXXXXXXXXXXXXXXXGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY 799
            MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPKIDKKASKRRSISKDSRSRSISRNRKHVIAKKSYREDKPSYRDERKPFREERRSARDDRDSYRNDRDSYRNDRRSFKEDRGRNDDRHSNRYERSGRRNRSRSRSPEFSRYSRGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY
Sbjct:    1 MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPKIDKKASKRRSISKDSRSRSISRNRKHVIAKKSYREDKPSYRDERKPFREERRSARDDRDSYRNDRDSYRNDRRSFKEDRGRNDDRHSNRYERSGRRNRSRSRSPEFSRYSRGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY 252

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000063924.1 (SMESG000063924.1)

HSP 1 Score: 304.679 bits (779), Expect = 1.393e-101
Identity = 252/252 (100.00%), Postives = 252/252 (100.00%), Query Frame = 2

Query:   44 MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPXXXXXXXXXXXXXXXXXXXXXXXXXXHVIAKKSYREDKPSYRDERKPFXXXXXXXXXXXXXXXXXXXXXXXXXXXFKEDRGRNDDRHXXXXXXXXXXXXXXXXXXXXXXXXXGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY 799
            MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPKIDKKASKRRSISKDSRSRSISRNRKHVIAKKSYREDKPSYRDERKPFREERRSARDDRDSYRNDRDSYRNDRRSFKEDRGRNDDRHSNRYERSGRRNRSRSRSPEFSRYSRGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY
Sbjct:    1 MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPKIDKKASKRRSISKDSRSRSISRNRKHVIAKKSYREDKPSYRDERKPFREERRSARDDRDSYRNDRDSYRNDRRSFKEDRGRNDDRHSNRYERSGRRNRSRSRSPEFSRYSRGTRDYEKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRDGY 252

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000045560.1 (SMESG000045560.1)

HSP 1 Score: 100.908 bits (250), Expect = 1.058e-23
Identity = 43/83 (51.81%), Postives = 64/83 (77.11%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKR 748
            P   +GIFGLS+KT E+ LW  F+KYGKI++++L+M+R   ES GY+FI+Y++I+ A++A+KE  G  +DG  IR+DYS GK+
Sbjct:  106 PCTCIGIFGLSKKTKEETLWDKFEKYGKIDNVRLIMDRGKRESLGYAFIDYKEIEFAMKAMKEAHGTEIDGNNIRLDYSVGKK 188

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000052838.1 (SMESG000052838.1)

HSP 1 Score: 98.2117 bits (243), Expect = 4.228e-22
Identity = 42/85 (49.41%), Postives = 62/85 (72.94%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            PS  +GIFGLS+KT+E  LWK F  +GKI S+ L++++ T ES G++FI YE++DSA  A+KE  G ++D + +R+DYS  K+ Y
Sbjct:   58 PSTCIGIFGLSKKTSERTLWKTFGNFGKIKSVSLIVDKFTKESLGFAFINYEELDSATNAIKETNGMTLDSKVVRVDYSITKKAY 142

[Close]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Match: SMESG000052829.1 (SMESG000052829.1)

HSP 1 Score: 93.2041 bits (230), Expect = 3.413e-21
Identity = 40/85 (47.06%), Postives = 62/85 (72.94%), Query Frame = 2

Query:  500 PSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSFIEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNY 754
            P   +G+FGL+++T E  LW+ F+K+G+I S+KL+M++   ES GY FI YED+ SA +A+KE  G ++DG+ IR+DYS  K+ +
Sbjct:   75 PCKCIGVFGLNKRTEEKILWETFEKFGRIASVKLIMDKYHQESLGYGFINYEDLGSATRAVKEASGMNLDGKVIRVDYSITKKAH 159

The following BLAST results are available for this feature:

BLAST of RRM domain-containing protein vs. Ensembl Human
BLAST of RRM domain-containing protein vs. Ensembl Celegans
BLAST of RRM domain-containing protein vs. Ensembl Fly
BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
BLAST of RRM domain-containing protein vs. Ensembl Xenopus
BLAST of RRM domain-containing protein vs. Ensembl Mouse
BLAST of RRM domain-containing protein vs. UniProt/SwissProt
BLAST of RRM domain-containing protein vs. TrEMBL
BLAST of RRM domain-containing protein vs. Ensembl Cavefish
BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
BLAST of RRM domain-containing protein vs. Ensembl Yeast
BLAST of RRM domain-containing protein vs. Ensembl Nematostella
BLAST of RRM domain-containing protein vs. Ensembl Medaka
BLAST of RRM domain-containing protein vs. Planmine SMEST

BLAST of RRM domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TRA2A	3.394e-17	40.22	transformer 2 alpha homolog [Source:HGNC Symbol;Ac...	[more]
TRA2A	3.471e-17	40.22	transformer 2 alpha homolog [Source:HGNC Symbol;Ac...	[more]
TRA2A	3.471e-17	40.22	transformer 2 alpha homolog [Source:HGNC Symbol;Ac...	[more]
TRA2A	1.249e-16	40.22	transformer 2 alpha homolog [Source:HGNC Symbol;Ac...	[more]
TRA2B	1.682e-15	39.13	transformer 2 beta homolog [Source:HGNC Symbol;Acc...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rsp-8	1.631e-13	38.89	SR Protein (Splicing factor) [Source:UniProtKB/Tr...	[more]
rsp-8	1.631e-13	38.89	SR Protein (Splicing factor) [Source:UniProtKB/Tr...	[more]
cpf-2	7.473e-12	37.21	Cleavage and Polyadenylation Factor [Source:UniPr...	[more]
cpf-2	7.473e-12	37.21	Cleavage and Polyadenylation Factor [Source:UniPr...	[more]
rbm-3.1	6.634e-10	37.31	RNA Binding Motif protein homolog [Source:UniProt...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tra2	2.810e-16	36.26	gene:FBgn0003742 transcript:FBtr0089616	[more]
tra2	6.698e-16	36.26	gene:FBgn0003742 transcript:FBtr0089615	[more]
tra2	6.698e-16	36.26	gene:FBgn0003742 transcript:FBtr0089619	[more]
tra2	1.097e-15	36.26	gene:FBgn0003742 transcript:FBtr0089620	[more]
tra2	1.097e-15	36.26	gene:FBgn0003742 transcript:FBtr0089621	[more]

BLAST of RRM domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tra2a	3.332e-17	42.35	transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G...	[more]
tra2a	3.332e-17	42.35	transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G...	[more]
tra2a	9.557e-17	42.35	transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G...	[more]
tra2a	1.272e-16	42.35	transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G...	[more]
cirbpa	9.175e-14	50.70	cold inducible RNA binding protein a [Source:ZFIN;...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
plekhg5	4.609e-16	39.13	pleckstrin homology and RhoGEF domain containing G...	[more]
rit1	2.004e-15	40.22	Ras-like without CAAX 1 [Source:Xenbase;Acc:XB-GEN...	[more]
cirbp	1.129e-12	42.25	cold inducible RNA binding protein [Source:NCBI ge...	[more]
cirbp	2.061e-12	42.25	cold inducible RNA binding protein [Source:NCBI ge...	[more]
cirbp	2.263e-12	42.25	cold inducible RNA binding protein [Source:NCBI ge...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tra2a	8.333e-17	40.22	transformer 2 alpha [Source:MGI Symbol;Acc:MGI:193...	[more]
Tra2a	8.574e-17	40.22	transformer 2 alpha [Source:MGI Symbol;Acc:MGI:193...	[more]
Cirbp	5.430e-16	47.95	cold inducible RNA binding protein [Source:MGI Sym...	[more]
Cirbp	1.146e-15	49.30	cold inducible RNA binding protein [Source:MGI Sym...	[more]
Tra2b	1.154e-15	39.13	transformer 2 beta [Source:MGI Symbol;Acc:MGI:1060...	[more]

BLAST of RRM domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6PFR5\|TRA2A_MOUSE	5.913e-16	40.22	Transformer-2 protein homolog alpha OS=Mus musculu...	[more]
sp\|Q13595\|TRA2A_HUMAN	5.998e-16	40.22	Transformer-2 protein homolog alpha OS=Homo sapien...	[more]
sp\|O02008\|TRA2_DROVI	1.229e-15	38.46	Transformer-2 sex-determining protein OS=Drosophil...	[more]
sp\|P60825\|CIRBP_RAT	8.016e-15	49.30	Cold-inducible RNA-binding protein OS=Rattus norve...	[more]
sp\|P60824\|CIRBP_MOUSE	8.016e-15	49.30	Cold-inducible RNA-binding protein OS=Mus musculus...	[more]

BLAST of RRM domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S6KMI2	5.009e-98	100.00	RRM domain-containing protein OS=Schmidtea mediter...	[more]
A0A3R7LVI2	6.271e-20	46.74	Transformer-2 protein OS=Penaeus vannamei OX=6689 ...	[more]
C0IRC8	9.348e-20	46.74	Transformer-2 protein OS=Penaeus monodon OX=6687 P...	[more]
C0IRC9	9.828e-20	46.74	Variant transformer-2 protein OS=Penaeus monodon O...	[more]
A0A3R7QGW1	1.951e-19	46.74	Transformer-2c OS=Penaeus vannamei OX=6689 GN=C7M8...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tra2a	6.584e-17	40.22	transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G...	[more]
tra2a	1.718e-16	41.18	transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G...	[more]
ENSAMXT00000034164.1	1.864e-14	37.78	pep primary_assembly:Astyanax_mexicanus-2.0:12:654...	[more]
cirbpa	4.920e-14	50.70	cold inducible RNA binding protein a [Source:ZFIN;...	[more]
tra2b	6.998e-13	35.87	transformer-2 protein homolog alpha-like [Source:N...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tra2a	3.015e-15	36.96	transformer 2 alpha homolog [Source:ZFIN;Acc:ZDB-G...	[more]
tra2b	3.410e-14	33.70	transformer 2 beta homolog [Source:ZFIN;Acc:ZDB-GE...	[more]
rbmx	1.718e-11	40.85	RNA binding motif protein X-linked [Source:NCBI ge...	[more]
rbmx	1.366e-10	35.16	RNA binding motif protein X-linked [Source:NCBI ge...	[more]
ncl	2.101e-10	37.18	nucleolin [Source:ZFIN;Acc:ZDB-GENE-030131-6986]	[more]

BLAST of RRM domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
NSR1	1.016e-10	28.57	Nucleolar protein that binds nuclear localization ...	[more]
IST3	1.435e-8	33.33	Component of the U2 snRNP; required for the first ...	[more]
NAM8	1.072e-7	31.00	RNA binding protein, component of the U1 snRNP pro...	[more]
RIE1	1.318e-7	33.33	Putative RNA binding protein; localizes to stress ...	[more]
HRP1	3.145e-7	35.44	Subunit of cleavage factor I; cleavage factor I is...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO44802	3.140e-19	44.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38445	1.752e-12	36.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42298	1.206e-8	35.44	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45916	3.856e-8	34.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36859	4.581e-8	36.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of RRM domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tra2a	1.368e-18	41.30	transformer-2 protein homolog alpha [Source:NCBI g...	[more]
tra2a	2.941e-14	36.96	transformer 2a [Source:NCBI gene;Acc:100049284]	[more]
cirbpa	4.359e-14	45.07	cold inducible RNA binding protein [Source:NCBI ge...	[more]
cirbpa	6.465e-14	45.07	cold inducible RNA binding protein [Source:NCBI ge...	[more]
tra2b	1.043e-13	36.96	transformer 2 beta homolog [Source:NCBI gene;Acc:1...	[more]

BLAST of RRM domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000063924.1	1.350e-101	100.00	SMESG000063924.1	[more]
SMESG000063924.1	1.393e-101	100.00	SMESG000063924.1	[more]
SMESG000045560.1	1.058e-23	51.81	SMESG000045560.1	[more]
SMESG000052838.1	4.228e-22	49.41	SMESG000052838.1	[more]
SMESG000052829.1	3.413e-21	47.06	SMESG000052829.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30014750 ID=SMED30014750|Name=RRM domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1354bp
AACTATCATATTTAATTTTTATACAGTAAATTAAAATTTTATAATGTCAG
GTAGAAATGAATCTAAGGTAAGTAGGAATTCTTCCTCACCTAATAAGTCA
AATGGCGAATATTGGTCATCAAAATCTAAATCTCGTTCGCCAAAAATTGA
TAAAAAGGCATCTAAAAGAAGATCCATTTCGAAGGATAGTAGATCAAGAT
CAATTTCTAGAAATCGTAAACATGTTATTGCCAAGAAATCCTATAGAGAA
GATAAACCATCATATAGAGATGAAAGAAAACCTTTTCGGGAAGAAAGACG
CTCTGCTAGAGATGATCGCGATTCTTATAGAAATGACCGTGATTCATATA
GGAATGATCGTAGATCTTTTAAGGAGGATAGAGGAAGAAATGATGATCGA
CATTCCAACAGATATGAAAGATCTGGTAGACGTAATCGTTCAAGATCAAG
ATCTCCTGAATTTAGTAGATATAGTAGAGGCACACGAGATTATGAAAAGC
CTTCGAATACTGTTGGGATTTTTGGTTTATCAAGAAAGACTACGGAAGAT
GCTTTATGGAAAATTTTTGATAAATATGGTAAAATTAATAGTCTGAAATT
GGTAATGAACAGAGAAACTGGAGAATCACGTGGTTACTCATTTATTGAAT
ATGAAGACATCGATTCTGCAATTCAAGCATTAAAGGAATGTCGAGGTAAA
AGTGTTGACGGTAGAGAAATTCGAATGGATTATAGCCGAGGAAAGCGAAA
TTATCAGAATAATGGCGATGAAAGATATTCCCGAAGTCGTGACGGATATC
AATCAAGAAAGAGGCAATCAAGATCGAGAAGCAAAAGTCGTTCGAATTAT
TCAGGTAAAGCATCAATTATTTGAATATTGATATAAAGTTGAACTGAAGC
CTCAGAATTTAAAGAAATTGAGATGTTTATTGTTTTTATTAGTGGGAAGC
CATTGATGTTTCAGTTGAAGCGATTTTATTAAAATAACGAGATAGAGCCT
GGGTTGATTAAAAGAATGAACAGATTTATTCGAAAGAAAGTTCGTTGAGA
TAAAGTTTCTAATCAAATGATGAGATAATTCTGTTCAAGAGAGTTGCCAT
GGTTGATTAATATTATAGATAGATTAACAGTGTGCATATTTTTGTTTTCG
TTATTTTGGGAAATGTAACACAAAATAAATTTTTAGTTTTATGTTCCGCA
TGGAAAATTTACCTTTAATAATAATTTTTTCTACGTTCGAGTTAAAATAA
ATATTATAAACATTAAGGGATTCTTTTATTCGTATTTTCCATATTTTATG
TATACCGATTCCCCGAAAAATATTAATATCTTTGTCAATCTTGTTAGCAA
TCAC

protein sequence of SMED30014750-orf-1

>SMED30014750-orf-1 ID=SMED30014750-orf-1|Name=SMED30014750-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=277bp
MSGRNESKVSRNSSSPNKSNGEYWSSKSKSRSPKIDKKASKRRSISKDSR
SRSISRNRKHVIAKKSYREDKPSYRDERKPFREERRSARDDRDSYRNDRD
SYRNDRRSFKEDRGRNDDRHSNRYERSGRRNRSRSRSPEFSRYSRGTRDY
EKPSNTVGIFGLSRKTTEDALWKIFDKYGKINSLKLVMNRETGESRGYSF
IEYEDIDSAIQALKECRGKSVDGREIRMDYSRGKRNYQNNGDERYSRSRD
GYQSRKRQSRSRSKSRSNYSGKASII*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0003676	nucleic acid binding
GO:0000166	nucleotide binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000429	neoblast
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR035979	RBD_domain_sf
IPR000504	RRM_dom
IPR012677	Nucleotide-bd_a/b_plait_sf

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 85..105
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 229..257
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 229..276
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 131..149
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 63..125
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..28
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..151
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 29..52
None	No IPR available	PANTHER	PTHR13952	U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD	coord: 152..264
IPR000504	RNA recognition motif domain	SMART	SM00360	rrm1_1	coord: 156..229 e-value: 4.1E-21 score: 86.1
IPR000504	RNA recognition motif domain	PFAM	PF00076	RRM_1	coord: 159..227 e-value: 1.3E-18 score: 66.6
IPR000504	RNA recognition motif domain	PROSITE	PS50102	RRM	coord: 155..233 score: 17.95
IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	GENE3D	G3DSA:3.30.70.330		coord: 144..270 e-value: 7.3E-27 score: 96.0
IPR035979	RNA-binding domain superfamily	SUPERFAMILY	SSF54928	RNA-binding domain, RBD	coord: 150..260