WD repeat and FYVE domain-containing protein 3
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014717 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751]) HSP 1 Score: 1237.25 bits (3200), Expect = 0.000e+0 Identity = 890/2784 (31.97%), Postives = 1405/2784 (50.47%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXX------------XXXXXXXXXXXXHYLKTIVSDSSFIPN---PMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD----------FCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKI--AEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRS--------PCDNNENHCQVYQIK--KFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE Q + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ E+ +D+++ L+ LI LTT G EL+P ++ + + GF +P P K S+RN AF VLQ+ FL A+T FL IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + + + +K ++ H+ IFK+V +++G+LE+ VN LH YA LK A DS NN +Q L LL+++ LT+L+ + N +FR+ GG+ C ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E S K W+ + + ++ E + + LT A++ EP+N +F + Y L +A+R LGCF SD+ I N N+Q + L D SVS L CS+ + ++Y A + FD+R S +H ++ + + P +KL V SS+ + ++I+HP A+++++ L+ ++ Q H ++LQ+ + L L +RN Q+MCE+ + LL A+ +E+H LH +FERLA+Q + P +R+FLRLA PL C + S+ Y+P + G G D + S ++ G + LTRVK L+ +TT D + P+FVE + EGFGCLFLP + ++ ++ I+ ++ GIG GER FPP G S+S+W C++ FSS HP+RLL++ R S + CL I ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL++T KL+Y+ S + ++++VYAYIGT P +I++L WR GP HF+EE L +S V+ I LGPNY+G+FQ P D + +P+ SLV EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P+++IHN+AGHL+G+ R++GA LIGY G+R F P P+ + VGG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L R + L P I+ LS L++ S +DL RFGQF+ TL E + + NN+ L++ EF + I + + + + E + EEL+K LGFDWI++FM+ +H +TV AMR LV LLS ++KF++G+ GWL TD VL + G +L N +REIN D+CH PGF LQS LP H +P +YF+L+AL L + +P+NL+ + P ISC + Q QF+ +S+ F+FG G +++ I +C+EA +LL M+R ML E +W+R+YP+TL++FF YLYH+ + S+ M DFL L ++P + D + S ++ F+ ++ + +++E C + T L + PA+K + DF +++I+D L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GGSY + NN++YF RVVDK+WQ + + ++I ++ +LI+Q ++R ++ +++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G N+ G+ +TW+ PD + +I + Q+ +N +W E+ +KKQ+LEE FK+ + ++ + P IE+ LK W +++ E I+ G ++ + Q KL+R+S L +L+ S SG + +S +E W+ HI+VV++L+D + +++ + Y+ +W +E EL RERGLWGP +GS LDKWML+ EGPCRMRKKM+ N+ FY HYPY P P E + Q K +++ A S D + Y Y +L+ S NP V++ I + ++PE +T + ++G S P GD + ++ QD + I +E+E+T N Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELP------------------LAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAES-KDALKDLVNLITSLTTYGVSELKPA-GITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAMNVFPSNTQP-------FQRLLEEDVISIESVS---------------PTLRHCSK----------LFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASV-GSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPV-SLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQGFPS----SNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPV-----------ISCRSKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTEAVFLLLGMLRSMLTSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEK----------------------KCISRGEALAPTTQS----KLSRVSSGFGLSKLTGSRRNRKESGLNK-----------HSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEY--------------YMRLA-------SGNPAIVQDAIVESSEGEAAQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSI--EEEEKTDN 2523 HSP 2 Score: 1193.33 bits (3086), Expect = 0.000e+0 Identity = 571/1049 (54.43%), Postives = 740/1049 (70.54%), Query Frame = 2 Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDE----YDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRP----NMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ ++ N I + + ++++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STVV VW M + K A ++L+ L GH + VTC + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT TGRS+QI+ MS M +WD NV++TG +DGVVR W +E++QVP + + A+ E Q + + +SS+ E DE D ++ S ++ + A+ R+ A D+ S ++ S+ +DG V + + ++ L LS P P N +L+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ S RN Sbjct: 2529 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLP----GSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAAS-CRATAAWCTDSGSDDSRRWSDQL---------------SLDEKDGFIFVNYSEG-QTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRN 3525
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751]) HSP 1 Score: 733.406 bits (1892), Expect = 0.000e+0 Identity = 343/508 (67.52%), Postives = 414/508 (81.50%), Query Frame = 2 Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQAD 9808 ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ ++ N I + + ++++F+H+LDN+ PSL PVKELK VGQI+ D Sbjct: 132 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGIS----VLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD 632
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: WDFY4 (WDFY family member 4 [Source:HGNC Symbol;Acc:HGNC:29323]) HSP 1 Score: 642.114 bits (1655), Expect = 0.000e+0 Identity = 335/788 (42.51%), Postives = 479/788 (60.79%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG-EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQID-PMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPI 10564 + QV ++ ++ EK+ F +QG V EG+LLFG +FYI + FTL T ++ + ++ +P + FN + + +D +S + ++RE+ + R+LLQ IA+E+F +G + L F ++K + F SL K + T + G ++ + Q+W+K +ISNF+YLMYLNT AGR+ ND MQYPVFPW+LADY SETL+L +P FR L KPMGAQ++ R +F +R++E + G+ T HY THYSSA+IVA YLVRM PFTQ F LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N + G Q+G VLGD+ LPPWA GD R+FI HR+ALE D+VSA+L+ WIDLIFGYKQ G AAV+AVN+FH FY +D+ SI DPL +S ++GF++NFGQ+PKQLF KPHP R + K + P++ P F+++L ++ PS VK++ K A+G I+ S ++LAVE+NK L+PPL+ R +WGF D S +G+Y SDK++ +E +G +C +C + ++T G STVV VW +S+ +P L L+ LYGH +AVTCLA + +++LLVSGS+D TCI+WDL + ++ +L H ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G I + WD ++ITG DG+VR+W E V++ + Sbjct: 2376 ERQVILQELL-DKEKVTQKFSLVIVQGHLVSEGVLLFGHQHFYICENFTLSPTGDVYCTRHCLSNISDPFI--------FNLCSKDRSTDHYSCQCHSYADMRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQPSL-------------KGKATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLPEFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPA-RTAAGKPLPGKDVSTPVSLPGHPQP----FFYSLQSLRPSQVTVKDMYLFSLGSESPKGAIGHIV-------------STEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCLCAVCPSPTTIVTSGTSTVVCVWELSMTKGRPR---------------GLRLRQALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSV 3108 HSP 2 Score: 325.094 bits (832), Expect = 7.446e-88 Identity = 273/1007 (27.11%), Postives = 475/1007 (47.17%), Query Frame = 2 Query: 2687 SIIVHPEAVISLIHLIPAI-RCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISL----TRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHV-ILVSTKEEVFGNRE--QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMG-TLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPIL---DYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINP--LNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWL----TGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKET 5650 + I+HP V ++ L+P + D Q + E+Q + + L ++N Q+MCE+ + L+ A++ PLHS + +FE+LA+Q + P +R FL L P T D +T C SG +++ P L T+ +G + + + + +I+ T + R A PSFVE +M EG+GCLF+P+++ +S SV R FPP GG +FS W + + + HP+R L+L R L + + C ++S+ P+ + ++VST+E+ F + + S+ + C LL W HL + + M +H + S L+GQ+I + K+ YI + F SM + VY YI T + S+L WR GP + EE ++ + I +LGP Y GNFQ + D ++ VAEE+V F L+ + SI ++ I YNE+D +IA+++++ ++ + P+ ++ N AGHLSG+ R++GA+ +G G+R F +P +D +GG +LLG++++A D +YA VK++ S L N ++ L H+ GY++++FLL+KK LL+ RIF L++ + G+ + F+ I N +F ++C+ LW++ + L ++ H+ E Q + ++++ + L+ ++I L + ++ P ++TII ++ + DL R G F+V+TL +E +I ++ L + + + I +RN +++L ++++ ++E K EE+ LG DW LL +Q +H ST VLA++ L+ L+ P +FRDG+ W+ G D+V MDN + Q + C LPGF L L HH IP++Y ++ L + + D K++ Sbjct: 826 AAIMHPGVVCIMVRLLPRLYHEDHPQLSE--EIQCSLASHIQSLVKSEKNRQVMCEA-GLLGTLMASCHRALVTSGSPLHSRLIRIFEKLASQAIEPDVLRQFLGLGIPSSLSATTKILDSSHTHRGNPGC----------------SGSQTAQGLAEGPWPAAPDAGLHPGVTQAPQPLGESQDSTTALQTALSLIS-MTSPRNLQPQRAALAPSFVEFDMSVEGYGCLFIPTLSTVMGTSTEYSVSGGIGTGAT---------RPFPPPGGLTFSCWFLISRHGAATEGHPLRFLTLVRHLARTEQPFVCFSVSLC--PDDLSLVVSTEEKEFQPLDVMEPEDDSEPSAGCQLQVRCGQLLACGQWHHLAVVVTKE-MKRHCTVSTCLDGQVIGSAKMLYIQ-ALPGPFLSMDPSAFVDVYGYIATPRVWKQKSSLIWRLGPTYLFEEAISMETLEVINKLGPRYCGNFQAVHVQGEDLDSEATPFVAEERVSFGLHIASSSITSVADIRNAYNEVDSRLIAKEMNISSRDNAMPVFLLRNCAGHLSGSLRTIGAVAVGQLGVRVFHSSPAASSLDFIGGPAILLGLISLATDDHTMYAAVKVLHSVLTSN-AMCDFLMQHICGYQIMAFLLRKKASLLNHRIFQLILSVAGTVELGFRSSAIT----------------NTGVFQHILCNFELWMN------TADNLELSLFSHLLEILQSPREGPRNAEAAHQA----------------QLIPKLIFLFNEPSLIPSKISTIIG-----ILACQLRGHFSTQDLLRIGLFVVYTLKPSSVNERQICMDGALDPSLPAGS-QTSGKTIWLRNQLLEMLLSVISSPQLHLSSESK--EEMFLKLGPDWFLLLLQGHLHASTTVLALKLLLYFLASPSLRTRFRDGLCAGSWVERSTEGVDIV---------MDNLKSQSPLPEQ---SPCLLPGFRVLNDFLAHHVHIPEVYLIVSTFFLQTPLTELMDGPKDS 1740 HSP 3 Score: 139.043 bits (349), Expect = 1.541e-31 Identity = 158/677 (23.34%), Postives = 312/677 (46.09%), Query Frame = 2 Query: 302 VSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPP---WDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284 VS + ++++K + E+A LA Q L + + G++LL + +L+ + + + + LP+ ++CLY+FF P ++ ++ + D V + F Q+L IC E L+ +L+ L +A+ C +S W++ VL+ I+ + S IQ++ + L+N+++ L + E+ + + +++S V+ L +F NS+GY ++ + L++ + +E + + L+ L+ LTTCG EL+ + I YP +EGF+ + +++N AF VLQ+VF A LC+++L I+T++ + N+F+LE F E + K VQE L++ +V L+YVP + + + ++K T + +++ + + + +F ++ +D G+L + + QL A ++K + + V + + EL +++ + L+ +N + + G +V F+K + +L ++ L+ + +EE MS +G + S ++Q L + + + + R FR F + L LEG + +PP W + ++ LE V L ++ AL +P N +F N + L E + LGCFG+ Sbjct: 99 VSDQLAQQLQKALVGKPAEQARLAAGQLLW-----WKGDVDQDGYLLLKSVYVLTGTDSETLGRVAESGLPALLLQCLYLFFVFP---LDKDELLESD-----------------LQVQKM------FVQMLLNICSDSQGLEGLLSGSELQSLL--IATTCLREHSCCFWKEPTFCVLRAIS-KAQNLSIIQYLQATDCVRLSLQNLSRLTDTLPAPEVSEAVSLILGFVKDSYPVSSALFLEFENSEGYPLLLKVLLRYDGLTQSEVD-PHLEELLGLVVWLTTCGRSELK----VFDSITYPQLEGFKFHHEAS-GVTVKNLQAFQVLQNVFHKASDSVLCIQVLSVIRTMWAWNARNFFLLEWTLQPISQFVEIMPLKPAPVQEHFFQLLEALVFELHYVPHEILRKVQHLIKESPGPSCTLMALQSILSIAGGDPLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKVSTPGVQDPERELTCVMLRIVVTLLKGSVRNAVVLKDHG-------MVPFIKIFLDDECYREASLSILEQLS-AINAEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILVTPKGRAAFRVSSGFNGLLSLLSDLEGS---LQEPPLQAWGAVSPRQTLELVLYTLCAVSAALHWDPVNGYFFRRNGLFEKLAEDLCLLGCFGA 723 HSP 4 Score: 67.0106 bits (162), Expect = 9.315e-10 Identity = 101/460 (21.96%), Postives = 198/460 (43.04%), Query Frame = 2 Query: 5900 MCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSL----PARKLIMDFFKMIIVDYFSLPKNSYQHV-IDIILECDIENTTQEHMKQFQTVFMNSLTEHFM------AVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLI-----SQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLK-LNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQIC-------LKTWNSYIESENIGTAS----SHWGRISL 7171 +C+E A +LL M++ ++Q +E+ W + +P ++L+F + L H +FL L A +P + N SPE+ ++ T+E L + PAR+ + +F ++++ + + Q + ++++LE ++ T + + FQ+ + S E F A G+ + A NI F ++V+K++ + DP I+ ++ I + +R +LY S N++IL+ LS+ ++ + + L L ++ +F NS+ F++CL+H L+ L G+ ST++ +++K+ + L + I+ ++LWQ++ ++Q LE+AFKI LS IE++ LK W Y+ SE AS +H +++L Sbjct: 1762 LCTEGALLLLEMLKATMSQPL--AGSEDGAWAQTFPASVLQF-LSLVHRTYPQDPAWRAPEFLQTLAIAAFPLGAQKGVGAESTRNTSSPEAAAEGDS----------------TVEGLQAPTKAHPARRKLREFTQLLLRELLLGASSPKQWLPLEVLLEASPDHATSQQKRDFQSEVLLSAMELFHMTSGGDAAMFRDGKEPQPSAEAAAAPSLANISCFTQKLVEKLYSGMFSADPRHILLFILEHIMVVIETASSQRDTVLSTLYSSLNKVILYCLSK------PQQSLSECLGLLSILGFLQEHWDVVFATYNSNISFLLCLMHCLLLLNERSYPEGFGLEPKPRMSTYHQVFLSPNEDVKEKREDLPSLSDVQHNIQKTVQTLWQQLVAQRQQTLEDAFKIDLSVKPGEREVKIEEVTPLWEETMLKAWQHYLASEKKSLASRSNVAHHSKVTL 2196
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: LYST (lysosomal trafficking regulator [Source:HGNC Symbol;Acc:HGNC:1968]) HSP 1 Score: 431.024 bits (1107), Expect = 7.634e-120 Identity = 253/717 (35.29%), Postives = 385/717 (53.70%), Query Frame = 2 Query: 8528 FSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQF-------EKRYREW---DDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQP-----VKELK---------NAVGQIIQADLNGTNSNAVGSVPS-SVLAVEQNKCLIPPL---------------YTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCA-----GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 +++ EI+EVHKR + L+ AVE+FL +GR LLAF K+++ +Y H+I + +E G+ + +N W G+I+NF+YL +LN AGRS+NDLMQYPVFP+ILADY SETLDL +R L KP+ Q + + ++ E+ YR+ DDP PYHYG+HYS++ V +LVRM PFT+ FL Q FD+ DR FHS TW +S +M D+KELIPEFFYLP FL N FD G +QNG + + LPPWA+ D R FI HR+ALE DYVS ++ +WIDL+FGYKQ G A+V+A+NVFH Y G +D+ +++DP++R A+ I +GQ P+QLF H ++ P + +N I+ P A + F + ++ P +K LK V + + +G ++ ++P+ ++ + +N CL+ ++ ++WG++D LR+ + S+ + + Y C + L TG V+ + +S P+ + Q +LYGH E +T L V Y++L+S SRD TCI+WDL R+CY++ L+GH +PV A+ SE +G +A+ G+ L LW+++G+ + V+ + I +V S + NV+ G +G+VR+WS Sbjct: 3067 WTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKVRDDVY---------------HNILTNNLPNLLEYGNITALTNL---------WYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIAVQYKEKEDRYVDTYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKASVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSR----PGAKLN--IEGELPAAVGLLVQFAFRETREQVKEITYPSPLSWIKGLKWGEYVGSPSAPVPVVCFSQPHGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGVRSMNSTDIQWSAILSWGYADNILRLKSKQSEPPVNFIQSSQQYQVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEI-------------EMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGGGSDLRLWTVNGDLVGHVHC----REIICSVAFSNQPEGVSINVIAGGLENGIVRLWS 3735
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: LRBA (LPS responsive beige-like anchor protein [Source:HGNC Symbol;Acc:HGNC:1742]) HSP 1 Score: 387.882 bits (995), Expect = 3.994e-109 Identity = 245/639 (38.34%), Postives = 343/639 (53.68%), Query Frame = 2 Query: 8516 MSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFP-----KKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISII---------------------------NKQIDPMAPLASSAPAERLF----YHNLDNMEPSLQPVK-ELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVV---RVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSG 10306 + K+ F EIR + RRYLLQ A+E+F+ + + FP KK+ N Y + V +S G Q +I S ++TQRW+ EISNF+YLM+LNT+AGRSYNDL QYPVFPW++ +YESE LDLT P+ FR L KP+GA + R F +RY W+D + P +HYGTHYS+A V +L+R+EPFT +FL LQGG FD ADR F SI W + SQ + +DIKELIPEF+YLP N N ++LG +G V+ D+ LPPWAK S EF+ +R ALE ++VS L++WIDLIFGYKQ G AV A+NVF++L YEG V++ SI DP+ R AV I +FGQ P QL +PHP + + +S + N Q P + A RLF +HNL + ++Q +L + +I ++ G + + + + V ++C + RY+ GF D S RV + D+ +LI+V +G V CL GG ++ R + + SG + + AP +A L GH VTC AV A L++SGS++ C++ + G + LR L G Sbjct: 771 LHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVN--YLPRVGVGTSF---------GLPQTRRISLASPR---QLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWED--DQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRN-SQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAK-TSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQVSPLMFTDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIASN-TGMHRRQITDLLDQSIQV-HSQCFVITSDNRYILVCGFWDKSFRVYSTDTGRLIQVV-----FGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKCSGIGDNPGSETAAP----RAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSMNGDL--LRTLEG 1378
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2]) HSP 1 Score: 787.334 bits (2032), Expect = 0.000e+0 Identity = 398/770 (51.69%), Postives = 515/770 (66.88%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRR-KMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGS--TSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQ--ANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNT-----ATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 DNQ + ++ E++H MFRCARIQGL+ EGLLLFG+ +FY++DGFTLLKT+EI +++ + ++H+PIVP T T + ++ KFS+ IREVHKRRYLLQPIA+EVF DGRN+LLAFPKK++++++ K +A +L+ S+ GQK N IE S+ S+ +G++SVTQRW G ISNFQYLM+LNTLAGR YNDL QYP+FPW+LADY S LD + STFR KPMGAQS +RL QF KR+REWDDPSGETPPY YGTHYSSAMIV YLVR+EPFTQ FL LQGGHFDLADRMFHS+ D W SAS++NMAD+KELIPEFF LP NTN FDLG KQNG+ + D+LLP W GD REFIR HR+ALE DYVS+HL+EWIDLIFGYKQ G+ AV+ N+FHHLFYEG+VD IDDPL R+A IGF+NNFGQIP QLFKKPHP K++ I N RLFYH + NM P KEL++A+G I Q D G V+A+EQNK I RY+ WG D S+R+G D+DK + V+EM + ++ C +E L G S + VW ++ +KP LS++ + L GH +A+TCL S+ +LVS SRD T ++W L M +RQL H V A+ +++ TG +A+ T LH+W+++GE LA +NT A + I+++ STM +WD NV++ G +DG+V+++S Sbjct: 2409 DNQTLLR-LLEQGEQLHSMFRCARIQGLETAEGLLLFGRDHFYVVDGFTLLKTKEIRDLDFLSQEMHDPIVPYPATGATQPPKSSRLCSKFSYNMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKIRDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGETPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLFKKPHPQKKVNILEGFSN---------TPGVTTSRLFYHAIHNMSAPQTPFKELRSAIGSIHQNDKIG------------VVALEQNKVFIGT--NRYITWGLPDRSVRMGQIDNDKSVCVHEMCE-VDEMTCAAAGDETTLFCGNTSGCITVWKVN---NKP-----------------LSMKKLSVLNGHSDAITCLVSCQSHAVLVSASRDLTVLVWHLSEMFLIRQLPKHPHAVLAVAVNDATGDIATACSTLLHVWTLNGELLAVLNTCDVAPAIDPQQMIISLAFSTMNEWDNDNVIMCGTSDGIVKIYS 3133 HSP 2 Score: 691.419 bits (1783), Expect = 0.000e+0 Identity = 676/2629 (25.71%), Postives = 1195/2629 (45.45%), Query Frame = 2 Query: 122 SLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVL-IILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS----IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSL---LVKAFIRLIEHNKIFKEVLKDMGILE----ISVNQLHSYAYNLKKEQDAGISDSVNNE-QDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRA--LEFIKVLTLSSGSEEDMSNFLGLIRS-INSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQE---LLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSV-SLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFS-SIATTHPIRLLSLARSLQGSNE-----------FISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHC--WIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKY--VSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETK--------INLNENNKSDLESAE-FKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALR---EINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFG-NSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGL-------TGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQ--TVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPN---NIYYFFSRVVDKVWQENYVDDPDV----IISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGP-CRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY--CFSMSKSILKT 7801 SL L+ F++Y K +S S +D +LL PLFHK+ +L F++V F + + S++V+E+++RA + T EA+ +I ++L+P E KG+ +L + +LS +I+ SLPST VK +Y+FFDLP + T+T + + + L D Q+++ +C + +EELVRK+DL LLF S N+ WRK A +L+ IA ++ + I+++ KK + +KN++ S + + + L L+ S+ + LLD+F + GY +I++FL+ +ET+ + +R+++++ L G E+ P+ + + F+LP+P S+RN AF +L VFL + ++ +++ + +IY DPANYFIL+ + +F ++L +K +V+ +L+ LI+ V L+++P +E+ SL V++KT A T++ +V+ +LI + I K+ +++G+L+ I Y N++ S S ++ Q +L LL D LT++I N ++N +LF + G+ ++ +V V + R+ L+ +K L + + +++ + + + ++ I +NL + +L++L V++ESH+ RI FRK F+ L+ LE F+ + P D I +E +LE+V I + T++++ EPSN +YF +++ S+T +R F ++ +I E +E W S +L+++ + + V L DN +A GN + C + + +++ A++ ++ + SD + N + S ++ S++VHP A+IS++ L+P+I ++T I Q Y+ L + +RN QIMC+ V MP LL + + ENH L L ERL+ Q +TP +R FLRL PLCC+ + ++DD + + ++ GGP+ L RVK+L+ + T ++Q PSFVE +M EGF L+LP + ER+FPP GFSF TWI + S A HPIRLL++ R++ N ++C ++ + +L+ST+E ++ + ++A+ + + Q C W HL + F+R ++K S S +LNG+ I T+KL Y++ N + + SV A +GT P + S L +R + EEP+TA V + +L P+YIGN+Q L EEK+VFSL A TL +I +Y ++D ++++ L + P + S+P+R++ N H GAGR+ G +++GY G+R F+P P+ ++D +GG + G++AMA D+E LYA +K + S + LL ++ Y++++ LL+ K +L+S I ++ +TG+AD + H +++ N + F +++CDL +W SE + ++ Y ++D +++ R +S L+ RI+ ++ NT +E + LI I+ + + GQ + TL TSE++ +++E K +ES++ ++ + IRN II L NS + ++ ++L++ LGFDW+ M P VH T+ LA+R L+ +L+ P + +F++G GWL+ D V++ R ++L + A+ +IN + + GF L+ L+ H P Y+ +++LL+G I + F C+ QF E V +FG NST +S +A S C +A L M+R + + + W P T+++ ++Y ++ F ++A +F++ L T AM S+ + S SP++ F ++ + P +++MD K I D + + +ID IL+ +I + Q T ++S+ EH + D+LS LPP NI NI SR VD W + + +L + S+ + + E + R+ LF LSR I +Q + + +T ++++ F L HL+ L PD + +DN + + + Q+ A +W ++ K+ L+EE FK Q +++ + + W +++S+ L +GG S+ + +Q QIS K NR++ S + R ++ S++T + S S + +W+ H+S++KEL+ + + + + + W E+EL RERG+WGP S L+K+ LD EGP RMR+K+IPN FY YP+RP+ +P + ++ KVA S D + YY C + L T Sbjct: 10 SLLHLRKTFSEYLKIPVSGSRSNDPSRLL----PLFHKVMSMYTPQQLNAEFKEVVHFATFLCSVLVKEVRQRAASTGTIEAAQSIAEFLRPG-------TELKGYTILEAIRFLLSSEDEIMIDAACKVSLPSTLVKTIYLFFDLPAAA----------TTVTVTDLTENATETEDEMLKNNEKLHDMIGQIMEGLCRFKCVSEELVRKDDLLLLFVGTTSQVAEANNCWRKLCARLLEVIADKSITNAVIKYVIVKKCVRIFVKNLSSAPSNSHSDAQKTAESIICLSCFLKNSAYLTDQLLDEFYEADGYTVIKDFLL------KSETDNEIVRNILLMAISLVNSGKFEITPQ---YTSGLVQLPAFQLPIPAGNGLSVRNLNAFALLYHVFLESTSESTSCTVIDILHSIYTCDPANYFILDKEYPLSIFIDQLERKPHAVRVKLLELIEFAVFQLSHIPCRELISLCVLLKTEISAGKTAMCTIIVQMCFKLITVDAIIKDAFREVGLLDALCFIIRRMFEMYEKNIQNASFTVTSTSSRSQDQLKLSLLTTDLLTIIIKNNTENGKLFTECFGAKLLIEIVCEVNEEWRSSLLQLVKQLLIVAPTDQYIMHLVNTLQDRIPIENLEVMFSLLKALLGVVRESHKVRIQFRKSGGFLALSALLLGLEKRFTDL-HPAGDGRIPREQCQMLEFVHIIFKVFTLSMRFEPSNAKYFSTEITWDSITSLLRLTSIF-NESTVISIEETE------WKS---LTHTDLASEIAACHEVFRLDDNIEA----GNVPKGMPF------NIYFGCYVCRLIFNMALDNYEK---------------------MTSDIRW--NDDGASLEESIVSWTSSLLVHPGAIISMLCLLPSISASSMKWT--IAAQYYVSLLLKAILKSERNQQIMCQ-VDMPKHLLRIAEKLFLTENHILLQPFYYLLERLSYQSLTPNQLRSFLRLDSPLCCRSLDDDEDDDDDSKI------------------------------EIADNEGGPVPLQRVKALVSMMTPRDQ---------------------YIGTAPSFVEFDMSVEGFAALYLP--------------------SLAPMFSTTKAERIFPPLNGFSFCTWIYLDALSDKKADAHPIRLLTVTRAVAPPNSDPPSKKPSQTAHLACFQCQ-FSAFDRSLLISTEE---SDQPGADLEKTANFQTDKLIRITLADQVRCGEWFHLAVVFNR-SVLKSSQVSLYLNGRHISTQKLMYVAQNAGGAATQLAQ-TYSVNAVVGTLPALRRPSRLRFRLASIFLAEEPMTAETVRAVVQLQPHYIGNYQTA------STAPLFHEEKIVFSLSAAATQELTLAKIRTMYGKMDAEILSQHLGISPNDHSTPLRVLCNTISHAPGAGRTFGGVIVGYLGMRTFTPRPVPSLLDSIGGFASVYGLIAMAVDSEGLYASLKSLVSAIRSQPRLLATWNNNRSYQILAVLLEDKAKMLNSHIMHMVFNVTGTADTSRE------------HAPTIS---NPSAFEDLLCDLKVW-----------------KGAPSELHKMLLEHFYELITDHQLNNLQVVRKSS---------LLSRILLIIHDEPTMIKNT--DEIIFNLISAIMQPQCDSRSILKIGQSIAATLP---TSESECYEDSHLPFHISEIQKLFIESSDPPPEALHQVYIRNRLLNIIANFLANSNTQV--QQQMCDQLVRTLGFDWLFALMSPGVHSGTIYLALRILLLILNQPSLLARFKEGSANGGWLSEADSVVRNRAAVVLGFSVSAHGGAVGSKIDINPELSNCGGFAALEHLMAAHADKPYPYYAMLSLLVGQPISAL------------------RF---CD----QFNMELVWTHVFGLNST----SSVFEAINSA------------------------------NFCFDAIIPLFAMIRTSIYHQ----SSIHQPWTVTNPSTVVQMITFMYQNSPAFFNIAHTDEFILALFSTLIEDTNAMGVKSEVANRRSQDGGG--SPDAEYF---------------------QAFLAQPNVRIVMDLLKKICCDNLQVNTSKNDTIIDAILD-NISESGNTRKTQIACLTSLLHSVLEHTVGTDLLSSS--ALPPNTQAQNIVQIVANISLLSSRAVDAFWNGLVFGSESMRMLSTLYHLQVIASKKVNKAVNAEPITGCIMRMTLFILSRPI--------DSVPVQLSVLDALSTLVSKRYLFLSSNEAWFFASLTHLIFMLS-----------VTPDVLF--QFQDNSSSSDLDRTSAQVAMCACRVWSDVICAKQALIEETFKKQSVTDINAARALLSHSAGVYWQQFVDSQ-------------LRAIQTGG-SSAQGSAVTAKDIIQQQISSKFNRVA--SGITRFAAKRSMSTTTALPSSGSVAAWKS--TSTDKQVIFMWLRVHVSLIKELVRAQSTRYTEWHAHVRKWCLHDWHQWEAELTRERGIWGPERASKLEKFKLDLTEGPTTRMRRKLIPNRNFYHIYPFRPHLEAPS---------AKAQRAKVAISFDSKPYYETCLRHRRRTLDT 2293 HSP 3 Score: 158.688 bits (400), Expect = 8.364e-38 Identity = 69/137 (50.36%), Postives = 97/137 (70.80%), Query Frame = 2 Query: 10979 GFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389 G + R L+ R+ LTMHTA+ R DN +P+PI+++A SRDHRS+YVGD GRV+ W + GR ADHW++D + C C+ +F+L +R+HHCRNCG +FC+ CS+ E+ I R+ + +PVRVC KCF + QQSS Sbjct: 3219 GAQFVRVLVQRTALTMHTAFNRPDNVHPAPITAIAPSRDHRSLYVGDGIGRVWCWQSAEGGGR--ADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRKCFQRL--QQSS 3351
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2]) HSP 1 Score: 787.334 bits (2032), Expect = 0.000e+0 Identity = 398/770 (51.69%), Postives = 515/770 (66.88%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRR-KMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGS--TSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQ--ANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNT-----ATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 DNQ + ++ E++H MFRCARIQGL+ EGLLLFG+ +FY++DGFTLLKT+EI +++ + ++H+PIVP T T + ++ KFS+ IREVHKRRYLLQPIA+EVF DGRN+LLAFPKK++++++ K +A +L+ S+ GQK N IE S+ S+ +G++SVTQRW G ISNFQYLM+LNTLAGR YNDL QYP+FPW+LADY S LD + STFR KPMGAQS +RL QF KR+REWDDPSGETPPY YGTHYSSAMIV YLVR+EPFTQ FL LQGGHFDLADRMFHS+ D W SAS++NMAD+KELIPEFF LP NTN FDLG KQNG+ + D+LLP W GD REFIR HR+ALE DYVS+HL+EWIDLIFGYKQ G+ AV+ N+FHHLFYEG+VD IDDPL R+A IGF+NNFGQIP QLFKKPHP K++ I N RLFYH + NM P KEL++A+G I Q D G V+A+EQNK I RY+ WG D S+R+G D+DK + V+EM + ++ C +E L G S + VW ++ +KP LS++ + L GH +A+TCL S+ +LVS SRD T ++W L M +RQL H V A+ +++ TG +A+ T LH+W+++GE LA +NT A + I+++ STM +WD NV++ G +DG+V+++S Sbjct: 2407 DNQTLLR-LLEQGEQLHSMFRCARIQGLETAEGLLLFGRDHFYVVDGFTLLKTKEIRDLDFLSQEMHDPIVPYPATGATQPPKSSRLCSKFSYNMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKIRDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGETPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLFKKPHPQKKVNILEGFSN---------TPGVTTSRLFYHAIHNMSAPQTPFKELRSAIGSIHQNDKIG------------VVALEQNKVFIGT--NRYITWGLPDRSVRMGQIDNDKSVCVHEMCE-VDEMTCAAAGDETTLFCGNTSGCITVWKVN---NKP-----------------LSMKKLSVLNGHSDAITCLVSCQSHAVLVSASRDLTVLVWHLSEMFLIRQLPKHPHAVLAVAVNDATGDIATACSTLLHVWTLNGELLAVLNTCDVAPAIDPQQMIISLAFSTMNEWDNDNVIMCGTSDGIVKIYS 3131 HSP 2 Score: 691.804 bits (1784), Expect = 0.000e+0 Identity = 676/2629 (25.71%), Postives = 1195/2629 (45.45%), Query Frame = 2 Query: 122 SLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVL-IILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS----IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSL---LVKAFIRLIEHNKIFKEVLKDMGILE----ISVNQLHSYAYNLKKEQDAGISDSVNNE-QDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRA--LEFIKVLTLSSGSEEDMSNFLGLIRS-INSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQE---LLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSV-SLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFS-SIATTHPIRLLSLARSLQGSNE-----------FISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHC--WIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKY--VSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETK--------INLNENNKSDLESAE-FKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALR---EINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFG-NSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGL-------TGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQ--TVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPN---NIYYFFSRVVDKVWQENYVDDPDV----IISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGP-CRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY--CFSMSKSILKT 7801 SL L+ F++Y K +S S +D +LL PLFHK+ +L F++V F + + S++V+E+++RA + T EA+ +I ++L+P E KG+ +L + +LS +I+ SLPST VK +Y+FFDLP + T+T + + + L D Q+++ +C + +EELVRK+DL LLF S N+ WRK A +L+ IA ++ + I+++ KK + +KN++ S + + + L L+ S+ + LLD+F + GY +I++FL+ +ET+ + +R+++++ L G E+ P+ + + F+LP+P S+RN AF +L VFL + ++ +++ + +IY DPANYFIL+ + +F ++L +K +V+ +L+ LI+ V L+++P +E+ SL V++KT A T++ +V+ +LI + I K+ +++G+L+ I Y N++ S S ++ Q +L LL D LT++I N ++N +LF + G+ ++ +V V + R+ L+ +K L + + +++ + + + ++ I +NL + +L++L V++ESH+ RI FRK F+ L+ LE F+ + P D I +E +LE+V I + T++++ EPSN +YF +++ S+T +R F ++ +I E +E W S +L+++ + + V L DN +A GN + C + + +++ A++ ++ + SD + N + S ++ S++VHP A+IS++ L+P+I ++T I Q Y+ L + +RN QIMC+ V MP LL + + ENH L L ERL+ Q +TP +R FLRL PLCC+ + ++DD + + ++ GGP+ L RVK+L+ + T ++Q PSFVE +M EGF L+LP + ER+FPP GFSF TWI + S A HPIRLL++ R++ N ++C ++ + +L+ST+E ++ + ++A+ + + Q C W HL + F+R ++K S S +LNG+ I T+KL Y++ N + + SV A +GT P + S L +R + EEP+TA V + +L P+YIGN+Q L EEK+VFSL A TL +I +Y ++D ++++ L + P + S+P+R++ N H GAGR+ G +++GY G+R F+P P+ ++D +GG + G++AMA D+E LYA +K + S + LL ++ Y++++ LL+ K +L+S I ++ +TG+AD + H +++ N + F +++CDL +W SE + ++ Y ++D +++ R +S L+ RI+ ++ NT +E + LI I+ + + GQ + TL TSE++ +++E K +ES++ ++ + IRN II L NS + ++ ++L++ LGFDW+ M P VH T+ LA+R L+ +L+ P + +F++G GWL+ D V++ R ++L + A+ +IN + + GF L+ L+ H P Y+ +++LL+G I + F C+ QF E V +FG NST +S +A S C +A L M+R + + + W P T+++ ++Y ++ F ++A +F++ L T AM S+ + S SP++ F ++ + P +++MD K I D + + +ID IL+ +I + Q T ++S+ EH + D+LS LPP NI NI SR VD W + + +L + S+ + + E + R+ LF LSR I +Q + + +T ++++ F L HL+ L PD + +DN + + + Q+ A +W ++ K+ L+EE FK Q +++ + + W +++S+ L +GG S+ + +Q QIS K NR++ S + R ++ S++T + S S + +W+ H+S++KEL+ + + + + + W E+EL RERG+WGP S L+K+ LD EGP RMR+K+IPN FY YP+RP+ +P + ++ KVA S D + YY C + L T Sbjct: 10 SLLHLRKTFSEYLKIPVSGSRSNDPSRLL----PLFHKVMSMYTPQQLNAEFKEVVHFATFLCSVLVKEVRQRAASTGTIEAAQSIAEFLRPG-------TELKGYTILEAIRFLLSSEDEIMIDAACKVSLPSTLVKTIYLFFDLPAAA----------TTVTVTDLTENATETEDEMLKNNEKLHDMIGQIMEGLCRFKCVSEELVRKDDLLLLFVGTTSQVAEANNCWRKLCARLLEVIADKSITNAVIKYVIVKKCVRIFVKNLSSAPSNSHSDAQKTAESIICLSCFLKNSAYLTDQLLDEFYEADGYTVIKDFLL------KSETDNEIVRNILLMAISLVNSGKFEITPQ---YTSGLVQLPAFQLPIPAGNGLSVRNLNAFALLYHVFLESTSESTSCTVIDILHSIYTCDPANYFILDKEYPLSIFIDQLERKPHAVRVKLLELIEFAVFQLSHIPCRELISLCVLLKTEISAGKTAMCTIIVQMCFKLITVDAIIKDAFREVGLLDALCFIIRRMFEMYEKNIQNASFTVTSTSSRSQDQLKLSLLTTDLLTIIIKNNTENGKLFTECFGAKLLIEIVCEVNEEWRSSLLQLVKQLLIVAPTDQYIMHLVNTLQDRIPIENLEVMFSLLKALLGVVRESHKVRIQFRKSGGFLALSALLLGLEKRFTDL-HPAGDGRIPREQCQMLEFVHIIFKVFTLSMRFEPSNAKYFSTEITWDSITSLLRLTSIF-NESTVISIEETE------WKS---LTHTDLASEIAACHEVFRLDDNIEA----GNVPKGMPF------NIYFGCYVCRLIFNMALDNYEK---------------------MTSDIRW--NDDGASLEESIVSWTSSLLVHPGAIISMLCLLPSISASSMKWT--IAAQYYVSLLLKAILKSERNQQIMCQ-VDMPKHLLRIAEKLFLTENHILLQPFYYLLERLSYQSLTPNQLRSFLRLDSPLCCRSLDDDEDDDDDSKI------------------------------EIADNEGGPVPLQRVKALVSMMTPRDQ---------------------YIGTAPSFVEFDMSVEGFAALYLP--------------------SLAPMFSTTKAERIFPPLNGFSFCTWIYLDALSDKKADAHPIRLLTVTRAVAPPNSDPPSKKPSQTAHLACFQCQ-FSAFDRSLLISTEE---SDQPGADLEKTANFQTDKLIRITLADQVRCGEWFHLAVVFNR-SVLKSSQVSLYLNGRHISTQKLMYVAQNAGGAATQLAQ-TYSVNAVVGTLPALRRPSRLRFRLASIFLAEEPMTAETVRAVVQLQPHYIGNYQTA------STAPLFHEEKIVFSLSAAATQELTLAKIRTMYGKMDAEILSQHLGISPNDHSTPLRVLCNTISHAPGAGRTFGGVIVGYLGMRTFTPRPVPSLLDSIGGFASVYGLIAMAVDSEGLYASLKSLVSAIRSQPRLLATWNNNRSYQILAVLLEDKAKMLNSHIMHMVFNVTGTADTSRE------------HAPTIS---NPSAFEDLLCDLKVW-----------------KGAPSELHKMLLEHFYELITDHQLNNLQVVRKSS---------LLSRILLIIHDEPTMIKNT--DEIIFNLISAIMQPQCDSRSILKIGQSIAATLP---TSESECYEDSHLPFHISEIQKLFIESSDPPPEALHQVYIRNRLLNIIANFLANSNTQV--QQQMCDQLVRTLGFDWLFALMSPGVHSGTIYLALRILLLILNQPSLLARFKEGSANGGWLSEADSVVRNRAAVVLGFSVSAHGGAVGSKIDINPELSNCGGFAALEHLMAAHADKPYPYYAMLSLLVGQPISAL------------------RF---CD----QFNMELVWTHVFGLNST----SSVFEAINSA------------------------------NFCFDAIIPLFAMIRTSIYHQ----SSIHQPWTVTNPSTVVQMITFMYQNSPAFFNIAHTDEFILALFSTLIEDTNAMGVKSEVANRRSQDGGG--SPDAEYF---------------------QAFLAQPNVRIVMDLLKKICCDNLQVNTSKNDTIIDAILD-NISESGNTRKTQIACLTSLLHSVLEHTVGTDLLSSS--ALPPNTQAQNIVQIVANISLLSSRAVDAFWNGLVFGSESMRMLSTLYHLQVIASKKVNKAVNAEPITGCIMRMTLFILSRPI--------DSVPVQLSVLDALSTLVSKRYLFLSSNEAWFFASLTHLIFMLS-----------VTPDVL----FQDNSSSSDLDRTSAQVAMCACRVWSDVICAKQALIEETFKKQSVTDINAARALLSHSAGVYWQQFVDSQ-------------LRAIQTGG-SSAQGSAVTAKDIIQQQISSKFNRVA--SGITRFAAKRSMSTTTALPSSGSVAAWKS--TSTDKQVIFMWLRVHVSLIKELVRAQSTRYTEWHAHVRKWCLHDWHQWEAELTRERGIWGPERASKLEKFKLDLTEGPTTRMRRKLIPNRNFYHIYPFRPHLEAPS---------AKAQRAKVAISFDSKPYYETCLRHRRRTLDT 2291 HSP 3 Score: 158.688 bits (400), Expect = 8.224e-38 Identity = 69/137 (50.36%), Postives = 97/137 (70.80%), Query Frame = 2 Query: 10979 GFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389 G + R L+ R+ LTMHTA+ R DN +P+PI+++A SRDHRS+YVGD GRV+ W + GR ADHW++D + C C+ +F+L +R+HHCRNCG +FC+ CS+ E+ I R+ + +PVRVC KCF + QQSS Sbjct: 3217 GAQFVRVLVQRTALTMHTAFNRPDNVHPAPITAIAPSRDHRSLYVGDGIGRVWCWQSAEGGGR--ADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRKCFQRL--QQSS 3349
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2]) HSP 1 Score: 786.949 bits (2031), Expect = 0.000e+0 Identity = 398/770 (51.69%), Postives = 515/770 (66.88%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRR-KMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGS--TSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQ--ANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNT-----ATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 DNQ + ++ E++H MFRCARIQGL+ EGLLLFG+ +FY++DGFTLLKT+EI +++ + ++H+PIVP T T + ++ KFS+ IREVHKRRYLLQPIA+EVF DGRN+LLAFPKK++++++ K +A +L+ S+ GQK N IE S+ S+ +G++SVTQRW G ISNFQYLM+LNTLAGR YNDL QYP+FPW+LADY S LD + STFR KPMGAQS +RL QF KR+REWDDPSGETPPY YGTHYSSAMIV YLVR+EPFTQ FL LQGGHFDLADRMFHS+ D W SAS++NMAD+KELIPEFF LP NTN FDLG KQNG+ + D+LLP W GD REFIR HR+ALE DYVS+HL+EWIDLIFGYKQ G+ AV+ N+FHHLFYEG+VD IDDPL R+A IGF+NNFGQIP QLFKKPHP K++ I N RLFYH + NM P KEL++A+G I Q D G V+A+EQNK I RY+ WG D S+R+G D+DK + V+EM + ++ C +E L G S + VW ++ +KP LS++ + L GH +A+TCL S+ +LVS SRD T ++W L M +RQL H V A+ +++ TG +A+ T LH+W+++GE LA +NT A + I+++ STM +WD NV++ G +DG+V+++S Sbjct: 2409 DNQTLLR-LLEQGEQLHSMFRCARIQGLETAEGLLLFGRDHFYVVDGFTLLKTKEIRDLDFLSQEMHDPIVPYPATGATQPPKSSRLCSKFSYNMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKIRDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGETPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLFKKPHPQKKVNILEGFSN---------TPGVTTSRLFYHAIHNMSAPQTPFKELRSAIGSIHQNDKIG------------VVALEQNKVFIGT--NRYITWGLPDRSVRMGQIDNDKSVCVHEMCE-VDEMTCAAAGDETTLFCGNTSGCITVWKVN---NKP-----------------LSMKKLSVLNGHSDAITCLVSCQSHAVLVSASRDLTVLVWHLSEMFLIRQLPKHPHAVLAVAVNDATGDIATACSTLLHVWTLNGELLAVLNTCDVAPAIDPQQMIISLAFSTMNEWDNDNVIMCGTSDGIVKIYS 3133 HSP 2 Score: 691.419 bits (1783), Expect = 0.000e+0 Identity = 676/2629 (25.71%), Postives = 1195/2629 (45.45%), Query Frame = 2 Query: 122 SLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVL-IILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS----IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSL---LVKAFIRLIEHNKIFKEVLKDMGILE----ISVNQLHSYAYNLKKEQDAGISDSVNNE-QDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRA--LEFIKVLTLSSGSEEDMSNFLGLIRS-INSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQE---LLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSV-SLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFS-SIATTHPIRLLSLARSLQGSNE-----------FISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHC--WIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKY--VSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETK--------INLNENNKSDLESAE-FKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALR---EINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFG-NSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGL-------TGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQ--TVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPN---NIYYFFSRVVDKVWQENYVDDPDV----IISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGP-CRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY--CFSMSKSILKT 7801 SL L+ F++Y K +S S +D +LL PLFHK+ +L F++V F + + S++V+E+++RA + T EA+ +I ++L+P E KG+ +L + +LS +I+ SLPST VK +Y+FFDLP + T+T + + + L D Q+++ +C + +EELVRK+DL LLF S N+ WRK A +L+ IA ++ + I+++ KK + +KN++ S + + + L L+ S+ + LLD+F + GY +I++FL+ +ET+ + +R+++++ L G E+ P+ + + F+LP+P S+RN AF +L VFL + ++ +++ + +IY DPANYFIL+ + +F ++L +K +V+ +L+ LI+ V L+++P +E+ SL V++KT A T++ +V+ +LI + I K+ +++G+L+ I Y N++ S S ++ Q +L LL D LT++I N ++N +LF + G+ ++ +V V + R+ L+ +K L + + +++ + + + ++ I +NL + +L++L V++ESH+ RI FRK F+ L+ LE F+ + P D I +E +LE+V I + T++++ EPSN +YF +++ S+T +R F ++ +I E +E W S +L+++ + + V L DN +A GN + C + + +++ A++ ++ + SD + N + S ++ S++VHP A+IS++ L+P+I ++T I Q Y+ L + +RN QIMC+ V MP LL + + ENH L L ERL+ Q +TP +R FLRL PLCC+ + ++DD + + ++ GGP+ L RVK+L+ + T ++Q PSFVE +M EGF L+LP + ER+FPP GFSF TWI + S A HPIRLL++ R++ N ++C ++ + +L+ST+E ++ + ++A+ + + Q C W HL + F+R ++K S S +LNG+ I T+KL Y++ N + + SV A +GT P + S L +R + EEP+TA V + +L P+YIGN+Q L EEK+VFSL A TL +I +Y ++D ++++ L + P + S+P+R++ N H GAGR+ G +++GY G+R F+P P+ ++D +GG + G++AMA D+E LYA +K + S + LL ++ Y++++ LL+ K +L+S I ++ +TG+AD + H +++ N + F +++CDL +W SE + ++ Y ++D +++ R +S L+ RI+ ++ NT +E + LI I+ + + GQ + TL TSE++ +++E K +ES++ ++ + IRN II L NS + ++ ++L++ LGFDW+ M P VH T+ LA+R L+ +L+ P + +F++G GWL+ D V++ R ++L + A+ +IN + + GF L+ L+ H P Y+ +++LL+G I + F C+ QF E V +FG NST +S +A S C +A L M+R + + + W P T+++ ++Y ++ F ++A +F++ L T AM S+ + S SP++ F ++ + P +++MD K I D + + +ID IL+ +I + Q T ++S+ EH + D+LS LPP NI NI SR VD W + + +L + S+ + + E + R+ LF LSR I +Q + + +T ++++ F L HL+ L PD + +DN + + + Q+ A +W ++ K+ L+EE FK Q +++ + + W +++S+ L +GG S+ + +Q QIS K NR++ S + R ++ S++T + S S + +W+ H+S++KEL+ + + + + + W E+EL RERG+WGP S L+K+ LD EGP RMR+K+IPN FY YP+RP+ +P + ++ KVA S D + YY C + L T Sbjct: 10 SLLHLRKTFSEYLKIPVSGSRSNDPSRLL----PLFHKVMSMYTPQQLNAEFKEVVHFATFLCSVLVKEVRQRAASTGTIEAAQSIAEFLRPG-------TELKGYTILEAIRFLLSSEDEIMIDAACKVSLPSTLVKTIYLFFDLPAAA----------TTVTVTDLTENATETEDEMLKNNEKLHDMIGQIMEGLCRFKCVSEELVRKDDLLLLFVGTTSQVAEANNCWRKLCARLLEVIADKSITNAVIKYVIVKKCVRIFVKNLSSAPSNSHSDAQKTAESIICLSCFLKNSAYLTDQLLDEFYEADGYTVIKDFLL------KSETDNEIVRNILLMAISLVNSGKFEITPQ---YTSGLVQLPAFQLPIPAGNGLSVRNLNAFALLYHVFLESTSESTSCTVIDILHSIYTCDPANYFILDKEYPLSIFIDQLERKPHAVRVKLLELIEFAVFQLSHIPCRELISLCVLLKTEISAGKTAMCTIIVQMCFKLITVDAIIKDAFREVGLLDALCFIIRRMFEMYEKNIQNASFTVTSTSSRSQDQLKLSLLTTDLLTIIIKNNTENGKLFTECFGAKLLIEIVCEVNEEWRSSLLQLVKQLLIVAPTDQYIMHLVNTLQDRIPIENLEVMFSLLKALLGVVRESHKVRIQFRKSGGFLALSALLLGLEKRFTDL-HPAGDGRIPREQCQMLEFVHIIFKVFTLSMRFEPSNAKYFSTEITWDSITSLLRLTSIF-NESTVISIEETE------WKS---LTHTDLASEIAACHEVFRLDDNIEA----GNVPKGMPF------NIYFGCYVCRLIFNMALDNYEK---------------------MTSDIRW--NDDGASLEESIVSWTSSLLVHPGAIISMLCLLPSISASSMKWT--IAAQYYVSLLLKAILKSERNQQIMCQ-VDMPKHLLRIAEKLFLTENHILLQPFYYLLERLSYQSLTPNQLRSFLRLDSPLCCRSLDDDEDDDDDSKI------------------------------EIADNEGGPVPLQRVKALVSMMTPRDQ---------------------YIGTAPSFVEFDMSVEGFAALYLP--------------------SLAPMFSTTKAERIFPPLNGFSFCTWIYLDALSDKKADAHPIRLLTVTRAVAPPNSDPPSKKPSQTAHLACFQCQ-FSAFDRSLLISTEE---SDQPGADLEKTANFQTDKLIRITLADQVRCGEWFHLAVVFNR-SVLKSSQVSLYLNGRHISTQKLMYVAQNAGGAATQLAQ-TYSVNAVVGTLPALRRPSRLRFRLASIFLAEEPMTAETVRAVVQLQPHYIGNYQTA------STAPLFHEEKIVFSLSAAATQELTLAKIRTMYGKMDAEILSQHLGISPNDHSTPLRVLCNTISHAPGAGRTFGGVIVGYLGMRTFTPRPVPSLLDSIGGFASVYGLIAMAVDSEGLYASLKSLVSAIRSQPRLLATWNNNRSYQILAVLLEDKAKMLNSHIMHMVFNVTGTADTSRE------------HAPTIS---NPSAFEDLLCDLKVW-----------------KGAPSELHKMLLEHFYELITDHQLNNLQVVRKSS---------LLSRILLIIHDEPTMIKNT--DEIIFNLISAIMQPQCDSRSILKIGQSIAATLP---TSESECYEDSHLPFHISEIQKLFIESSDPPPEALHQVYIRNRLLNIIANFLANSNTQV--QQQMCDQLVRTLGFDWLFALMSPGVHSGTIYLALRILLLILNQPSLLARFKEGSANGGWLSEADSVVRNRAAVVLGFSVSAHGGAVGSKIDINPELSNCGGFAALEHLMAAHADKPYPYYAMLSLLVGQPISAL------------------RF---CD----QFNMELVWTHVFGLNST----SSVFEAINSA------------------------------NFCFDAIIPLFAMIRTSIYHQ----SSIHQPWTVTNPSTVVQMITFMYQNSPAFFNIAHTDEFILALFSTLIEDTNAMGVKSEVANRRSQDGGG--SPDAEYF---------------------QAFLAQPNVRIVMDLLKKICCDNLQVNTSKNDTIIDAILD-NISESGNTRKTQIACLTSLLHSVLEHTVGTDLLSSS--ALPPNTQAQNIVQIVANISLLSSRAVDAFWNGLVFGSESMRMLSTLYHLQVIASKKVNKAVNAEPITGCIMRMTLFILSRPI--------DSVPVQLSVLDALSTLVSKRYLFLSSNEAWFFASLTHLIFMLS-----------VTPDVL----FQDNSSSSDLDRTSAQVAMCACRVWSDVICAKQALIEETFKKQSVTDINAARALLSHSAGVYWQQFVDSQ-------------LRAIQTGG-SSAQGSAVTAKDIIQQQISSKFNRVA--SGITRFAAKRSMSTTTALPSSGSVAAWKS--TSTDKQVIFMWLRVHVSLIKELVRAQSTRYTEWHAHVRKWCLHDWHQWEAELTRERGIWGPERASKLEKFKLDLTEGPTTRMRRKLIPNRNFYHIYPFRPHLEAPS---------AKAQRAKVAISFDSKPYYETCLRHRRRTLDT 2291 HSP 3 Score: 158.688 bits (400), Expect = 8.294e-38 Identity = 69/137 (50.36%), Postives = 97/137 (70.80%), Query Frame = 2 Query: 10979 GFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389 G + R L+ R+ LTMHTA+ R DN +P+PI+++A SRDHRS+YVGD GRV+ W + GR ADHW++D + C C+ +F+L +R+HHCRNCG +FC+ CS+ E+ I R+ + +PVRVC KCF + QQSS Sbjct: 3219 GAQFVRVLVQRTALTMHTAFNRPDNVHPAPITAIAPSRDHRSLYVGDGIGRVWCWQSAEGGGR--ADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRKCFQRL--QQSS 3351
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2]) HSP 1 Score: 786.949 bits (2031), Expect = 0.000e+0 Identity = 398/770 (51.69%), Postives = 515/770 (66.88%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRR-KMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGS--TSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQ--ANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNT-----ATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 DNQ + ++ E++H MFRCARIQGL+ EGLLLFG+ +FY++DGFTLLKT+EI +++ + ++H+PIVP T T + ++ KFS+ IREVHKRRYLLQPIA+EVF DGRN+LLAFPKK++++++ K +A +L+ S+ GQK N IE S+ S+ +G++SVTQRW G ISNFQYLM+LNTLAGR YNDL QYP+FPW+LADY S LD + STFR KPMGAQS +RL QF KR+REWDDPSGETPPY YGTHYSSAMIV YLVR+EPFTQ FL LQGGHFDLADRMFHS+ D W SAS++NMAD+KELIPEFF LP NTN FDLG KQNG+ + D+LLP W GD REFIR HR+ALE DYVS+HL+EWIDLIFGYKQ G+ AV+ N+FHHLFYEG+VD IDDPL R+A IGF+NNFGQIP QLFKKPHP K++ I N RLFYH + NM P KEL++A+G I Q D G V+A+EQNK I RY+ WG D S+R+G D+DK + V+EM + ++ C +E L G S + VW ++ +KP LS++ + L GH +A+TCL S+ +LVS SRD T ++W L M +RQL H V A+ +++ TG +A+ T LH+W+++GE LA +NT A + I+++ STM +WD NV++ G +DG+V+++S Sbjct: 2411 DNQTLLR-LLEQGEQLHSMFRCARIQGLETAEGLLLFGRDHFYVVDGFTLLKTKEIRDLDFLSQEMHDPIVPYPATGATQPPKSSRLCSKFSYNMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKIRDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGETPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLFKKPHPQKKVNILEGFSN---------TPGVTTSRLFYHAIHNMSAPQTPFKELRSAIGSIHQNDKIG------------VVALEQNKVFIGT--NRYITWGLPDRSVRMGQIDNDKSVCVHEMCE-VDEMTCAAAGDETTLFCGNTSGCITVWKVN---NKP-----------------LSMKKLSVLNGHSDAITCLVSCQSHAVLVSASRDLTVLVWHLSEMFLIRQLPKHPHAVLAVAVNDATGDIATACSTLLHVWTLNGELLAVLNTCDVAPAIDPQQMIISLAFSTMNEWDNDNVIMCGTSDGIVKIYS 3135 HSP 2 Score: 691.034 bits (1782), Expect = 0.000e+0 Identity = 676/2629 (25.71%), Postives = 1195/2629 (45.45%), Query Frame = 2 Query: 122 SLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVL-IILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS----IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSL---LVKAFIRLIEHNKIFKEVLKDMGILE----ISVNQLHSYAYNLKKEQDAGISDSVNNE-QDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRA--LEFIKVLTLSSGSEEDMSNFLGLIRS-INSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQE---LLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSV-SLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFS-SIATTHPIRLLSLARSLQGSNE-----------FISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHC--WIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKY--VSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETK--------INLNENNKSDLESAE-FKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALR---EINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFG-NSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGL-------TGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQ--TVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPN---NIYYFFSRVVDKVWQENYVDDPDV----IISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGP-CRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY--CFSMSKSILKT 7801 SL L+ F++Y K +S S +D +LL PLFHK+ +L F++V F + + S++V+E+++RA + T EA+ +I ++L+P E KG+ +L + +LS +I+ SLPST VK +Y+FFDLP + T+T + + + L D Q+++ +C + +EELVRK+DL LLF S N+ WRK A +L+ IA ++ + I+++ KK + +KN++ S + + + L L+ S+ + LLD+F + GY +I++FL+ +ET+ + +R+++++ L G E+ P+ + + F+LP+P S+RN AF +L VFL + ++ +++ + +IY DPANYFIL+ + +F ++L +K +V+ +L+ LI+ V L+++P +E+ SL V++KT A T++ +V+ +LI + I K+ +++G+L+ I Y N++ S S ++ Q +L LL D LT++I N ++N +LF + G+ ++ +V V + R+ L+ +K L + + +++ + + + ++ I +NL + +L++L V++ESH+ RI FRK F+ L+ LE F+ + P D I +E +LE+V I + T++++ EPSN +YF +++ S+T +R F ++ +I E +E W S +L+++ + + V L DN +A GN + C + + +++ A++ ++ + SD + N + S ++ S++VHP A+IS++ L+P+I ++T I Q Y+ L + +RN QIMC+ V MP LL + + ENH L L ERL+ Q +TP +R FLRL PLCC+ + ++DD + + ++ GGP+ L RVK+L+ + T ++Q PSFVE +M EGF L+LP + ER+FPP GFSF TWI + S A HPIRLL++ R++ N ++C ++ + +L+ST+E ++ + ++A+ + + Q C W HL + F+R ++K S S +LNG+ I T+KL Y++ N + + SV A +GT P + S L +R + EEP+TA V + +L P+YIGN+Q L EEK+VFSL A TL +I +Y ++D ++++ L + P + S+P+R++ N H GAGR+ G +++GY G+R F+P P+ ++D +GG + G++AMA D+E LYA +K + S + LL ++ Y++++ LL+ K +L+S I ++ +TG+AD + H +++ N + F +++CDL +W SE + ++ Y ++D +++ R +S L+ RI+ ++ NT +E + LI I+ + + GQ + TL TSE++ +++E K +ES++ ++ + IRN II L NS + ++ ++L++ LGFDW+ M P VH T+ LA+R L+ +L+ P + +F++G GWL+ D V++ R ++L + A+ +IN + + GF L+ L+ H P Y+ +++LL+G I + F C+ QF E V +FG NST +S +A S C +A L M+R + + + W P T+++ ++Y ++ F ++A +F++ L T AM S+ + S SP++ F ++ + P +++MD K I D + + +ID IL+ +I + Q T ++S+ EH + D+LS LPP NI NI SR VD W + + +L + S+ + + E + R+ LF LSR I +Q + + +T ++++ F L HL+ L PD + +DN + + + Q+ A +W ++ K+ L+EE FK Q +++ + + W +++S+ L +GG S+ + +Q QIS K NR++ S + R ++ S++T + S S + +W+ H+S++KEL+ + + + + + W E+EL RERG+WGP S L+K+ LD EGP RMR+K+IPN FY YP+RP+ +P + ++ KVA S D + YY C + L T Sbjct: 10 SLLHLRKTFSEYLKIPVSGSRSNDPSRLL----PLFHKVMSMYTPQQLNAEFKEVVHFATFLCSVLVKEVRQRAASTGTIEAAQSIAEFLRPG-------TELKGYTILEAIRFLLSSEDEIMIDAACKVSLPSTLVKTIYLFFDLPAAA----------TTVTVTDLTENATETEDEMLKNNEKLHDMIGQIMEGLCRFKCVSEELVRKDDLLLLFVGTTSQVAEANNCWRKLCARLLEVIADKSITNAVIKYVIVKKCVRIFVKNLSSAPSNSHSDAQKTAESIICLSCFLKNSAYLTDQLLDEFYEADGYTVIKDFLL------KSETDNEIVRNILLMAISLVNSGKFEITPQ---YTSGLVQLPAFQLPIPAGNGLSVRNLNAFALLYHVFLESTSESTSCTVIDILHSIYTCDPANYFILDKEYPLSIFIDQLERKPHAVRVKLLELIEFAVFQLSHIPCRELISLCVLLKTEISAGKTAMCTIIVQMCFKLITVDAIIKDAFREVGLLDALCFIIRRMFEMYEKNIQNASFTVTSTSSRSQDQLKLSLLTTDLLTIIIKNNTENGKLFTECFGAKLLIEIVCEVNEEWRSSLLQLVKQLLIVAPTDQYIMHLVNTLQDRIPIENLEVMFSLLKALLGVVRESHKVRIQFRKSGGFLALSALLLGLEKRFTDL-HPAGDGRIPREQCQMLEFVHIIFKVFTLSMRFEPSNAKYFSTEITWDSITSLLRLTSIF-NESTVISIEETE------WKS---LTHTDLASEIAACHEVFRLDDNIEA----GNVPKGMPF------NIYFGCYVCRLIFNMALDNYEK---------------------MTSDIRW--NDDGASLEESIVSWTSSLLVHPGAIISMLCLLPSISASSMKWT--IAAQYYVSLLLKAILKSERNQQIMCQ-VDMPKHLLRIAEKLFLTENHILLQPFYYLLERLSYQSLTPNQLRSFLRLDSPLCCRSLDDDEDDDDDSKI------------------------------EIADNEGGPVPLQRVKALVSMMTPRDQ---------------------YIGTAPSFVEFDMSVEGFAALYLP--------------------SLAPMFSTTKAERIFPPLNGFSFCTWIYLDALSDKKADAHPIRLLTVTRAVAPPNSDPPSKKPSQTAHLACFQCQ-FSAFDRSLLISTEE---SDQPGADLEKTANFQTDKLIRITLADQVRCGEWFHLAVVFNR-SVLKSSQVSLYLNGRHISTQKLMYVAQNAGGAATQLAQ-TYSVNAVVGTLPALRRPSRLRFRLASIFLAEEPMTAETVRAVVQLQPHYIGNYQTA------STAPLFHEEKIVFSLSAAATQELTLAKIRTMYGKMDAEILSQHLGISPNDHSTPLRVLCNTISHAPGAGRTFGGVIVGYLGMRTFTPRPVPSLLDSIGGFASVYGLIAMAVDSEGLYASLKSLVSAIRSQPRLLATWNNNRSYQILAVLLEDKAKMLNSHIMHMVFNVTGTADTSRE------------HAPTIS---NPSAFEDLLCDLKVW-----------------KGAPSELHKMLLEHFYELITDHQLNNLQVVRKSS---------LLSRILLIIHDEPTMIKNT--DEIIFNLISAIMQPQCDSRSILKIGQSIAATLP---TSESECYEDSHLPFHISEIQKLFIESSDPPPEALHQVYIRNRLLNIIANFLANSNTQV--QQQMCDQLVRTLGFDWLFALMSPGVHSGTIYLALRILLLILNQPSLLARFKEGSANGGWLSEADSVVRNRAAVVLGFSVSAHGGAVGSKIDINPELSNCGGFAALEHLMAAHADKPYPYYAMLSLLVGQPISAL------------------RF---CD----QFNMELVWTHVFGLNST----SSVFEAINSA------------------------------NFCFDAIIPLFAMIRTSIYHQ----SSIHQPWTVTNPSTVVQMITFMYQNSPAFFNIAHTDEFILALFSTLIEDTNAMGVKSEVANRRSQDGGG--SPDAEYF---------------------QAFLAQPNVRIVMDLLKKICCDNLQVNTSKNDTIIDAILD-NISESGNTRKTQIACLTSLLHSVLEHTVGTDLLSSS--ALPPNTQAQNIVQIVANISLLSSRAVDAFWNGLVFGSESMRMLSTLYHLQVIASKKVNKAVNAEPITGCIMRMTLFILSRPI--------DSVPVQLSVLDALSTLVSKRYLFLSSNEAWFFASLTHLIFMLS-----------VTPDVLF--QFQDNSSSSDLDRTSAQVAMCACRVWSDVICAKQALIEETFKKQSVTDINAARALLSHSAGVYWQQFVDSQ-------------LRAIQTGG-SSAQGSAVTAKDIIQQQISSKFNRVA--SGITRFAAKRSMSTTTALPSSGSVAAWKS--TSTDKQVIFMWLRVHVSLIKELVRAQSTRYTEWHAHVRKWCLHDWHQWEAELTRERGIWGPERASKLEKFKLDLTEGPTTRMRRKLIPNRNFYHIYPFRPHLEAPS---------AKAQRAKVAISFDSKPYYETCLRHRRRTLDT 2293 HSP 3 Score: 158.688 bits (400), Expect = 8.366e-38 Identity = 69/137 (50.36%), Postives = 97/137 (70.80%), Query Frame = 2 Query: 10979 GFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389 G + R L+ R+ LTMHTA+ R DN +P+PI+++A SRDHRS+YVGD GRV+ W + GR ADHW++D + C C+ +F+L +R+HHCRNCG +FC+ CS+ E+ I R+ + +PVRVC KCF + QQSS Sbjct: 3221 GAQFVRVLVQRTALTMHTAFNRPDNVHPAPITAIAPSRDHRSLYVGDGIGRVWCWQSAEGGGR--ADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRKCFQRL--QQSS 3353
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: sel-2 (Putative neurobeachin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q19317]) HSP 1 Score: 340.117 bits (871), Expect = 5.371e-93 Identity = 216/625 (34.56%), Postives = 319/625 (51.04%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISII-----NKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAV------------GQIIQADLNGTNSNAVG--SVPSSVLAVEQNKCLIPPLYTRYV-------------------------AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERIL------ITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249 +++ EIR + RRYLLQ A+E+FL + AF + K K + + + ++ + ++ S + + +W+K EISNF YLM+LNT+AGR++NDL QYPVFPWIL +Y S+TLDL+ S FR L KP+GA SE R F RY WDD + P +HYGTHYS+ +L+R+EPF F+ L G FD DR+ HSIKD+W+ Q + D+KELIPE FYLP N++KF+LG + +G + D++LPPWA+ F+ HR+ALE D VS LN+WIDLIFGYKQ G AV A NVF+HL YEG V + P + +A+ I +FGQ P QL + HP + ++ ++ ++ + M S++P L + + P V +N V G ++ L+ SNA G S+P + A + P+ R++ A G+ D S R+ + DS +V + +GD++ + +E L +TG V +W+ + T AG G P S ++ L GH +++ L V+A + L+VSG D Sbjct: 1749 RWNLQEIRAIFLRRYLLQNTALELFLASRTAIMFAFDSEDAVK---KVVYQLPRVGVGVKYGLPQSRKTSLMTP------RQLFKHSDMCAKWQKREISNFDYLMFLNTVAGRTFNDLSQYPVFPWILTNYTSDTLDLSVASNFRDLSKPIGALSEARRKFFNDRYTSWDD--DQVPAFHYGTHYSTPAFTLNWLLRVEPFASMFINLHDGKFDHPDRITHSIKDSWDRC-QRDSHDVKELIPELFYLPEMFRNSSKFNLGRRADGTPVDDVVLPPWAES-PEHFVLMHRQALESDLVSCQLNQWIDLIFGYKQRGAEAVRATNVFYHLTYEGTVTPKMAETPGQVAAIEQQILSFGQTPSQLLTEAHPPRHSIMSMAPTMFRRHDEDLCMMMKYISNSPVVYLAANTFHQL-PQPTVVGVAQNLVFSLNKWDNSYSYGASQRSALSMDPSNAEGQVSLPLTADAQLASAASTTPVARRHLGDAFDQRLTVQCSNFVTTTDSKFIFACGYPDYSFRIVDTDSG---RVRQAVYGHGDVVTCIARSETSLFSDCYVVTGSMDCTVVLWHWN-----GTTGFIAGEYNQPGEVP--SPRSILTGHEASISALCVSAEHGLVVSGCED 2349
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: bchs (gene:FBgn0043362 transcript:FBtr0079144) HSP 1 Score: 1158.67 bits (2996), Expect = 0.000e+0 Identity = 567/1068 (53.09%), Postives = 740/1068 (69.29%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVP-----STPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAP---AERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEM-PDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATG---RSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQ--MRPNMRK--------------------LRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCF 11362 DN+ + ++ EKI FMFRCAR+QGLD EGLLLFG+ + YI+DGFTLLK REI +I+ +P +EPI+P S+ T +H+ + KF++ EIREVHKRRYLLQPIA+EVF DGRN+LL+FP+K++NK+ +F+ +A++L NAQ S++GQK+ + +E + IFS +GE SVTQRW +GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE LDLT+P TFR +PMGAQ+E RL QF+KR++EWDDP GETPPYHYGTHYSSAMIV YLVR+EPF+Q FLKLQGGHFDLADRMFHSIK+ W SAS+ NMAD+KELIPEFFYLP FL+N N FDLG KQNG L ++LPPWAK D REFIR HR ALECDYVS HL+ WIDLIFG KQ G AAV+AVNVFHHLFYEGNVDIY+IDDPLK++A IGFINNFGQIPKQLFKK HP K++ S + IDP + + ++ +RLF+HNLDN++PSLQP+KELK VGQI+Q D +V AVEQNK ++PP YT+Y+AWGF+D SLR+G YD+D+ V E G+I+ C N ++++T G S+VV +W N +L+++ +L+GH +AVTCLA +A+YN++VSGSRD T I+WD+ R ++RQL GHA VAA+ I+E+TG +A+C+ T+LH+WSI+G+ LA VNT G R +QIL V S + +WD NV+ITG TDGVVRMWSLE+ QVPI VSSQ ++V S ++++ D+ + + KS+ + + +S SI + S + E+ + S+ ++ ++ A S+ ++ + +RP+ LRKGF WQRQL+FRSKLTMHTAY+R DNA P+ I++L +S+DH+ +YVGD RGR+F WSV ++PGR +ADHW++DE A+ C+ C ++F+L ER+HHCRNCG VFCNKCS+ E+EI RLR+ KPVRVC C+ Sbjct: 2457 DNETFLR-LLEEQEKISFMFRCARVQGLDTFEGLLLFGKEHCYIVDGFTLLKNREIRDIDTLPPGAYEPIIPNSGGTSSTTSRAVSHKLRQCSKFAYEEIREVHKRRYLLQPIALEVFSEDGRNYLLSFPRKVRNKVNQRFLALATALNDNAQQSVAGQKRTASVEQ-TAGIFSGLIGETSVTQRWVRGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEELDLTNPKTFRDFSRPMGAQAEERLEQFQKRFKEWDDPHGETPPYHYGTHYSSAMIVCSYLVRLEPFSQPFLKLQGGHFDLADRMFHSIKEAWLSASKLNMADVKELIPEFFYLPEFLSNFNNFDLGTKQNGETLNHVILPPWAKHDPREFIRLHRSALECDYVSQHLHLWIDLIFGCKQQGPAAVDAVNVFHHLFYEGNVDIYNIDDPLKKNATIGFINNFGQIPKQLFKKAHPAKKM--GGSRHSALIDPTSLIQGNSTVLQTDRLFFHNLDNLKPSLQPIKELKGPVGQILQPD-------------KTVFAVEQNKVMMPPSYTKYIAWGFADHSLRIGLYDTDRASFVSEASAQNSGEILTCACPNAKMIVTAGTSSVVTIWKFDANRK------------------SLAVKHSLHGHTDAVTCLAASAAYNVIVSGSRDGTAIVWDMTRFTFVRQLRGHAGVVAAVSINELTGDIATCSATWLHVWSINGDALAMVNTCVGSADRMQQILCVAFSQIREWDQQNVIITGSTDGVVRMWSLEHTQVPIDRK-----LKRGTEVSSQDKPDTV-----SLEGKDNKDDKMSLMKQIKSLSQSEEEMEIVKSASESSISEASQHSHGSSKSAEAGPKAEVQGERRKSSISGAKSLHEMKSATVEGQGSSYDPKSNEDEHAIRPSKSDTSLTDGFVVIDNDRHKGDQILRKGFRWQRQLMFRSKLTMHTAYDRKDNAEPASITALTVSKDHKILYVGDARGRIFSWSVTEQPGRGVADHWLKDEGADQCVKCHVKFTLYERKHHCRNCGQVFCNKCSRFESEISRLRILKPVRVCQACY 3479 HSP 2 Score: 1070.84 bits (2768), Expect = 0.000e+0 Identity = 817/2626 (31.11%), Postives = 1306/2626 (49.73%), Query Frame = 2 Query: 122 SLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS-IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETE-QDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXI--------SNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENS-EGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSD-SSFIPNPMK---LPVPPSSIN----NCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIAT-THPIRLLSLARSLQGSNEF-ISCLNISIINSPNHVILVSTKEEVFGNREQ-ENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYEN-PIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTL--SALGTSETKINL-NENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPA---------------------ALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKL--------IMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPP--GGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKR--QITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIV------GYSTWY-NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXX-----XXXXXXXXXXEQI---CLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSC-LDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELY 7765 SL LK LF +Y + D LY+++PLF K+F P ++ E+F DV FC VS LMV EI+KRA+NQ TE AS+AIV++L+ T+ E + GW+LL L +L+ G LI+ M A++PST VKCLY+FFDLP E + ++ G +++ RR +L F Q+L ++C YP EEL R +DL LLF A+ S CP HN WRK AA++L TI+ NGL+ + + +I+ K ++ C+ N+ + + +EIV++FVT+F L++SS V+Q+L+DDFR SQGY + +FL+K + S E Q +IR+L+++I+ L CG+ ELRP P + + ++ F+LP ++ +RN YAF VLQ+VFL + T LC IL+AI +Y + ANYFILE + T F+E++H KS +QE+ +L++ IV LN+VP KE+ SLS+++K + L +K + ++ HN +FK+V +++GILEI V L YA +++K S V E + L ++ S N +LFR+ GG+ CV LV F + +AL ++ L LS+G ++DM + L L+ S++ + KI++L L LK+SHR R VFRKV FV V L+G +L P I +Q+L+ ++ + L A++ EP+N ++F +S +SL + +R LGCFG L + + E S +++F + LS +S++ L C + + +Y A++ F+ L + T+ SD + + +P K PV PS +N + IVHP V+ ++ L+PA+ D ++LQ+Y+ E + L +RN QIMC+ + +LL + A+ E+HPLH + ERLA Q + P +R FLRL +PL C I + QP +KL GGP+ LTR+K+L+ +TT + D+ + +P FVE++M EGFGCL+LP + ++ I+ N IGGIG G+R+FPP G ++STW CV+KFS T H +RLL+L R++ E ++CL+I ++++ + I+VST+E + R+ ++ S + +A C LL E W +LV+ +R ++K+SS +L+G + T+KL+YI+ + ++ S+ T T ++ YIGT P + S LCW+QG H IE+ LT V I +LGP+Y+G+ Q P L ++ + LV E++V+ L A +S TL +I K+Y+ D IA+QL+++ E ++PI+I+HN+AGHL+GAGRSLG +++GY G+R FSP P++ +ID VGG VLLGI+AMA D E+LYA VK + + NR+ E++ Y+ + KKK+HLL+S I L GL G+ + QD ++ N F +++CDL +W + N + L S SD + +K + DL L+ +++ ++ Q + E L L+E ++ + DL FGQ++ L + G E + L + N ++ + IYL RN C L T I +++ K LG DW+LLFMQP VH +TV++A+R LV + + ++++FRD G+L T++V Q++ L +P E+ + ++PGF L+ L+ HH +P++YF++ AL++G +K + ++F+ + V +FL+G ++N Q L +++ +C E +LL M+R +++ EC W+ +P T+++ LY + +F V M D + L ++P + S P P S T + G+ + + E+L+ P KL I+DF ++I+VD L + VID++L+ E+ Q+QT + +L +H +A D+L G+ LPL P I N++Y +R+VDK+WQ +P I ++ +LI Q ++R ++ E L+ S NR ILF LSR + + ++ + + + +G+G N + EF+ CL + L+QL + I+ +TW+ NP + + + ++ NQ++ L I A +W+E+ KK +EE FK+ L+ S + EQ+ K W +Y+E+E T + W L QI K+ +++ L RL S + + R + ++ E A H+ ++K+L+D + + Y+ W E EL RERGLWGP GSC LDKW+LD+ EGP RMRKK + N+ FY HYPYRP DN + K+KVA+S D + Y Sbjct: 61 SLTTLKKLFNEYTHPREPLSEQERDDKLYEMLPLFCKVFSSCPSNDMSEKFWDVVAFCQQVSRLMVSEIRKRASNQSTEAASIAIVKFLEVETTE----ETSSGWMLLATLNLLANGDVSLIQVMTAAAVPSTLVKCLYLFFDLPIVEDD-----------EPSADGGAVSEFNAH--ERRTLLQKVFVQLLVKLCSYPYPAEELARMDDLTLLFSAITSPCPIHNIVWRKNAAEILTTISRNGLTDAVVSYIHSKGCMALCVDNMQRLTFGNPLEIVEMFVTVFCFLKDSSQVSQILMDDFRASQGYVFLSDFLLKFDNNRSQSLEIQAAIRNLVLMISSLCMCGFYELRP-PASQFNTAFKLQNFQLPQATSRETCVRNVYAFQVLQNVFLKSTTPALCCTILDAISRVYHSENANYFILESEQTLSSFAERIHMKSPQIQEKFYDLLEFIVFQLNFVPCKELISLSLLLKHNQSTSCSILCLKTLLNILRHNAVFKDVYREVGILEIFVGCLTRYAAHVQKITKGDESVVVELENESEEELFDTLGKHVLEALTMLLGGGASNNAQLFREYGGAKCVHELVKFKHCRPQALGIVRELILSAGGDDDMLHILSLMHSVSPLQVEFKIQILNMLLGCLKDSHRTRTVFRKVGGFVYVTSVFVSLDGSMAL----PQPDIPQQDLILLLQIVFQTLATAMRFEPANAKFFHQEISSSSLCDTLRLLGCFGGSSALQDYTGTYEPQQSLLKYYHEIFSGDILSVSFSEDVPYPLS---------------------------YVCIVFRLLYSIALDNFEAPNLSG-------------IITLFSDPPTTLRSPSKELAPPVHPSQLNLTQPSPEPRIVHPGVVLCMLQLLPAVEYDMAPL-QAVQLQVYLSEIIKSLVRSERNQQIMCDH-GLAEKLLKLTRRALAEESHPLHVPMQYILERLAAQALQPTELRQFLRLGEPLSCADIDLQ---------------QP-----YKL--------------------GGPVPLTRIKTLVSMTTPR------------------DFRAHGSSTLPPFVELDMSAEGFGCLYLP------SLAPQATATAGGTIDANSIGGIGAGDRIFPPQTGLTYSTWFCVEKFSDPKTDPHCVRLLTLVRTIHNPREENLACLSI-LLSARDKAIVVSTQETLVTPRKSIGDWEPEGSDDGIARIWCPDLLHEGQWHNLVVVLNR-AVLKNSSLFLYLDGVPMHTQKLHYIAQHPAAGNASL-TSPTQIFGYIGTPPIWRRYSRLCWKQGVCHLIEDVLTQQTVQTIYQLGPHYMGSLQAPQLGKQSESLAPLVPEDRVLLGLNAKAVSKLTLVKIRKVYSRADNKSIAKQLNMNSHENATPIKILHNSAGHLAGAGRSLGGVVVGYLGVRVFSPHPVSAMIDTVGGCNVLLGIIAMAQDVESLYAGVKALTCVVRSNRAAQAEMDRKRCYQTLGMFFKKKKHLLNSHILHLTFGLVGTVNSG-QD---------------MSAIPNVTAFQDLLCDLEIWHNAPNGLLRSLLEHLLELVVES------------SDKKQN----------VKIMRDLQLLVKLLHIITQIQ----DHSTREILFSLLETLLGGQPRHTDLLLFGQYVAAKLPHAHSGGLERAVLLPSMKNPAEDQDGGVAQNIYL---RNRCL--SLLHGLLFTPRNTVNYVICDDISKTLGMDWLLLFMQPHVHFTTVIIAVRILVVICANESFLVRFRDATHNGGYLRFTEMVSQRKMLGLGAQQLNQRPTNGTGTVIVATPQNTIQHLPTQIAGEVRAAALNIPGFQLLEWLMNHHLDVPELYFLITALIMGQPVKVL------------------------ATEHTKFDLDRVWSFLWGAPV----SANTQ--------------LPKLN-----------------ICPEGVCVLLAMVRGIVHG--GECA----PWLHSHPETIIQLLFSLYQNLTDFAPVMMTGDVVTSLVAVLFP-----LASRPADSE---PNSGASTPTDDTGS------SFALPPPETLHGAPQPKLTAHPVCNCIIDFLRVIVVDSLGLNMQGKPTPVIDLVLDAAPESAELPLQVQYQTQIIIALMDHLLAADVLVGEQAALPLVPLLQSQMQYIAPNVFYLTARIVDKLWQGCLARNPHDIFDFVIKLIVQAKRRSSSLSLEHLHHSLNRSILFLLSRPTDDSRADQMSVLEALHKIIQHRLLIFGAG-----NHELEFIGCLTYCLLQLTADMKIILEPATSRNTTWHVNPQTETAEPKDEDLNQLQGRNL---IVGAAFRVWEELYVCKKPAIEEVFKVSLTSPPPNSKAPDLQTTREQVMELASKLWFNYVEAERKATYRAPW-------------------------ELHTQIQSKIQKVTGG--LSRL----------TSRTKTKKEELVRTRSTLTREAAYESTGIHVQLIKDLLDLRAKQYQQMLQHTQRYVYQDWVQSEMELTRERGLWGP-TGSCSLDKWILDTTEGPHRMRKKTMRNDVFYLHYPYRP-ELELADNRQ--------LKYKVASSLDSKTY 2374
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: rg (gene:FBgn0266098 transcript:FBtr0344651) HSP 1 Score: 382.104 bits (980), Expect = 2.174e-105 Identity = 226/637 (35.48%), Postives = 344/637 (54.00%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERL-----FYHN--LDNMEPSLQPVKELKNAV-----------------------------------GQIIQAD----LNGTNSNA-------VGSVPSSVLAVEQNKCLIPPLYTRY-VAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249 K+ F E+R + RRYLLQ +A+E+FL + L AFP + K K I+ + + ++ I ++ S + M ++TQ+W++ EISNF+YLM+LNT+AGR+YNDL QYP+FPW+L +YES+ LDL+ PS +R L KP+GA + +R FE+RY WD S PP+HYGTHYS+A +LVR+EPFT FL LQGG FD DR+F S+ +W++ Q + +D+KELIPE+++LP N++ + LG++++G ++ DI LPPWAK EF+R +R ALE ++VS L++WIDLIFGYKQ G A+ A NVF++L YEG+VD+ + DP+ R AV I NFGQ P QL +PHP + + +S P+ SA E L FY N + ++ + P L + V Q + D ++GTN+N+ +G S +L + N C + + +R+ +A GF D S RV ++ K++++ +G V C+ ++ + +G V +W+ + G + +A L GH +AVT + ++A L+VSGS + Sbjct: 2705 KWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVK---KVIKALPRVGVGIKYGIPQTRRASMMSP------RQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWD--SDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNC-QRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKS-PEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHLS----------PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSN-CFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIV-----FGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGEGDVPTP-----------RATLTGHEQAVTSVVISAELGLVVSGSSN 3301
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: rg (gene:FBgn0266098 transcript:FBtr0344649) HSP 1 Score: 381.719 bits (979), Expect = 2.482e-105 Identity = 226/637 (35.48%), Postives = 344/637 (54.00%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERL-----FYHN--LDNMEPSLQPVKELKNAV-----------------------------------GQIIQAD----LNGTNSNA-------VGSVPSSVLAVEQNKCLIPPLYTRY-VAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249 K+ F E+R + RRYLLQ +A+E+FL + L AFP + K K I+ + + ++ I ++ S + M ++TQ+W++ EISNF+YLM+LNT+AGR+YNDL QYP+FPW+L +YES+ LDL+ PS +R L KP+GA + +R FE+RY WD S PP+HYGTHYS+A +LVR+EPFT FL LQGG FD DR+F S+ +W++ Q + +D+KELIPE+++LP N++ + LG++++G ++ DI LPPWAK EF+R +R ALE ++VS L++WIDLIFGYKQ G A+ A NVF++L YEG+VD+ + DP+ R AV I NFGQ P QL +PHP + + +S P+ SA E L FY N + ++ + P L + V Q + D ++GTN+N+ +G S +L + N C + + +R+ +A GF D S RV ++ K++++ +G V C+ ++ + +G V +W+ + G + +A L GH +AVT + ++A L+VSGS + Sbjct: 2725 KWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVK---KVIKALPRVGVGIKYGIPQTRRASMMSP------RQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWD--SDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNC-QRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKS-PEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHLS----------PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSN-CFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIV-----FGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGEGDVPTP-----------RATLTGHEQAVTSVVISAELGLVVSGSSN 3321
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: rg (gene:FBgn0266098 transcript:FBtr0344668) HSP 1 Score: 381.719 bits (979), Expect = 2.622e-105 Identity = 226/637 (35.48%), Postives = 344/637 (54.00%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERL-----FYHN--LDNMEPSLQPVKELKNAV-----------------------------------GQIIQAD----LNGTNSNA-------VGSVPSSVLAVEQNKCLIPPLYTRY-VAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249 K+ F E+R + RRYLLQ +A+E+FL + L AFP + K K I+ + + ++ I ++ S + M ++TQ+W++ EISNF+YLM+LNT+AGR+YNDL QYP+FPW+L +YES+ LDL+ PS +R L KP+GA + +R FE+RY WD S PP+HYGTHYS+A +LVR+EPFT FL LQGG FD DR+F S+ +W++ Q + +D+KELIPE+++LP N++ + LG++++G ++ DI LPPWAK EF+R +R ALE ++VS L++WIDLIFGYKQ G A+ A NVF++L YEG+VD+ + DP+ R AV I NFGQ P QL +PHP + + +S P+ SA E L FY N + ++ + P L + V Q + D ++GTN+N+ +G S +L + N C + + +R+ +A GF D S RV ++ K++++ +G V C+ ++ + +G V +W+ + G + +A L GH +AVT + ++A L+VSGS + Sbjct: 2498 KWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVK---KVIKALPRVGVGIKYGIPQTRRASMMSP------RQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWD--SDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNC-QRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKS-PEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHLS----------PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSN-CFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIV-----FGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGEGDVPTP-----------RATLTGHEQAVTSVVISAELGLVVSGSSN 3094
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: rg (gene:FBgn0266098 transcript:FBtr0344648) HSP 1 Score: 381.719 bits (979), Expect = 2.695e-105 Identity = 226/637 (35.48%), Postives = 344/637 (54.00%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERL-----FYHN--LDNMEPSLQPVKELKNAV-----------------------------------GQIIQAD----LNGTNSNA-------VGSVPSSVLAVEQNKCLIPPLYTRY-VAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249 K+ F E+R + RRYLLQ +A+E+FL + L AFP + K K I+ + + ++ I ++ S + M ++TQ+W++ EISNF+YLM+LNT+AGR+YNDL QYP+FPW+L +YES+ LDL+ PS +R L KP+GA + +R FE+RY WD S PP+HYGTHYS+A +LVR+EPFT FL LQGG FD DR+F S+ +W++ Q + +D+KELIPE+++LP N++ + LG++++G ++ DI LPPWAK EF+R +R ALE ++VS L++WIDLIFGYKQ G A+ A NVF++L YEG+VD+ + DP+ R AV I NFGQ P QL +PHP + + +S P+ SA E L FY N + ++ + P L + V Q + D ++GTN+N+ +G S +L + N C + + +R+ +A GF D S RV ++ K++++ +G V C+ ++ + +G V +W+ + G + +A L GH +AVT + ++A L+VSGS + Sbjct: 2462 KWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVK---KVIKALPRVGVGIKYGIPQTRRASMMSP------RQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWD--SDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNC-QRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKS-PEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHLS----------PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSN-CFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIV-----FGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGEGDVPTP-----------RATLTGHEQAVTSVVISAELGLVVSGSSN 3058
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-070705-153]) HSP 1 Score: 1198.73 bits (3100), Expect = 0.000e+0 Identity = 849/2671 (31.79%), Postives = 1359/2671 (50.88%), Query Frame = 2 Query: 26 KSNLEMNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKG-GLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKT-----CNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLK--KEQDAGISDSVNN---EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPP---WDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXX-------------XXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQ-----------MQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEV---FGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYEN---------PIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIYLIEIRNMCFXXXXXXXXXXXXXE--TNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQ--NLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY 7768 K L+MN V+RI+ + + +D L L+ LF++ + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE+ Q + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP HN WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + +I+LE+ +E+ +D+++ L+ L+ LTT G EL+P L+ + + GF +P P K ++RN AF+VLQ+ FL A++ L ILEAI IY D ANYFILE Q+T F+E++ K VQ + L++ +V LNYVP KE+ S+SV++K+ C++ T +LL +L H+ +F +V +++G+LE+ VN LH YA LK + + DS NN EQ +L L+++ LT+L+ + N LFR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S + L LK +L +L VL+ESHR R VFRKV FV L+ +E + PP W+ + + ++ E + I LT A++ EP+N +F + Y L +A+R LGCF SD + N+Q + +E D I N L CS+ + +MY A + FD+R Y + S S +KL + SS ++ +++HP AV++++ L+P++ D Q H ++LQ+ + L L +RN QI+CE+ + LL A+ +E+HPLH +FERLA+Q + P +R+FLRL +PL C + S+ Y+ L G G D I++ ++ G + LTRVK L+ +TT D + P+FVE++ EGFGCLFLP + ++ S+ + ++ G+G GER FPP G S+STW CV++FS+ +HP+RLL++ R S + CL I ++++ + ++VSTKEE+ + + E S A F C L+ E W HL+L + GM+K+S + +++GQ++ T KL+Y+ + S + ++++VY+YIGT P ++S L WR GP HF+EE L A+ V+ I LGPNY+G+FQ L ++ P+G LV EEKV FSL+A+++S T+ +I K+YN+LD IA+QL + E ++P++++HNA GHL+G+ R++GA +IGY G+R F P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L L ++ + P T I LS L++ + N DL RFGQF+ TL E + + N+ ++ EF + I + + + E T + EEL++ LGFDW+L+FM+ +H STV A+ LV LLS + +F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQ+LLP H +P+IYFML+AL I +P++L QF+ +S+ F+FG +A +G L N MC+E A +LL M+R MLN E +W+R+YPITL++FF YLYH+ + + DFL L ++P + D S ++ F ++ + +++E C N+ N +T + PA+K + DF +++I+D + P + +ID++LE E +T+ K+FQ+ ++S+ E +A D+L G+ +LP+ GGSY + NN++YF RVVDK+WQ + + +++ ++ +LI+Q ++R ++ +S+Y NR IL++LSR K + + + L T + + P N D EFV CL H LI L G ++ G+ +TW+ ++ ++N D+ + + + +W E+ +K+Q+LE+ FK+ + ++ + P +E+ K+W +++ E I+ G V+ + Q KL+R+S L +L+ S SG N++S +E W+ HI+VV++L+ +++ + Y+ +W +E EL RERGLWGP +GS LDK+ LD EGPCRMRKKM+ N+ FY HYPY P + E + + +++ A S D + YY Sbjct: 16 KKPLKMNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFSELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSTMNEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEVNQSE----ETSRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHMPEVPAATQTELP------------------LADRRALLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPHNLPWRKSAGEVLTTISRHGLSVNVVKYIHEKECLSTCIQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRMCQGYTFLIDLMIRLEQAKEDES-KDALKDLVNLVTALTTYGVSELKPA-GLTTGAPFLLPGFVVPQPSGKGHTVRNIQAFSVLQNAFLKAKSGRLARMILEAIANIYAADYANYFILEAQHTLSQFAERVTKLP-EVQSKYFELLEFVVFGLNYVPCKELFSVSVLLKSSTSYGCSITATRTLL-----KLGRHHPVFSDVFREVGLLEVLVNLLHKYAALLKDPTQTHSDQGDSKNNVAEEQKQLAWLVMETLTVLLQGSNTNAGLFREFGGARCVHNIVKYRQCREHALMIIQQLVLSPSGDDDMGTLLGLMHSAPTAELQLKTDILRALLAVLRESHRTRTVFRKVGGFVYVTSLLLAMERS---LCSPPVIGWEKVNQNKVFELLHTIFCTLTAAMRYEPANSHFFRTEIQYEKLADAVRLLGCF-SDAKKVGPATVFPSNAQPFQR----LLE------------------DEIIPAENVCPTLKHCSK----------LFIYMYKMATDSFDSRAEQVPPCLTHETSLPSPWGTPAITRKRHGYSSSSNSASGKALTDLKLHLGNSSQHSSDPVVIHPGAVLAMLDLLPSVSSD-TQPEHALDLQLAVANILQLLVHSERNQQILCEA-GLHSRLLQRCSCALGDEDHPLHPPLQRMFERLASQALEPMVLREFLRLGNPLNCGAWDKKLLKQYRVHKPSSLSYEAEMRNSMTLSMEGFGPDSVFTINEDNSQYRISRSLVRSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVELDTSLEGFGCLFLP--SLAPHNAPSSNANTSGVSDGAVVSGMGNGERFFPPPSGLSYSTWFCVERFSTPPQSHPVRLLTVVRRATSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQSYVDDFSEESSFYEILPCCARFRCADLITEGQWHHLLLVMSK-GMLKNSMATLYIDGQMVSTVKLHYVHNSPGGSASANPPVVSTVYSYIGTPPAQRQLSTLVWRLGPTHFLEEVLPAASVAAIYELGPNYVGSFQAVYLPCKDSKTEAVPPCPVG-LVPEEKVSFSLFAHSVSALTVAKIRKVYNKLDSKAIAKQLGVSSHESATPVKLVHNAVGHLNGSARTVGAAVIGYLGVRAFVTKPVATNLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRPLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLLREFQLIPKLL-LTLRDQSLS-------QPTITAIGNVLSLLLQ---GFPNT-YDLLRFGQFISSTLPTFAVCEKFVIMENTNEEKIDRGADEEFGGLLSSNLILLRNRLLDILLKQLFSCKEKGTVNAQACEELVRTLGFDWLLMFMEEHIHSSTVTAALLILVVLLSNQSILSRFKEGLSGGGWLDHTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFPVLQTLLPKHTNVPEIYFMLMALFFQQPITELPESL-------------------------QFDLDSIWTFIFGVPAS--------------SATVVGSLHN--------------------MCTETAFLLLAMLRSMLNLPWQ--SEEEGSWLREYPITLMQFFRYLYHNIPDLAPMWHSPDFLCTLAATVFPFNIRPYSEMVSDLDDEASSPTEEFKAFVTDTGMNRSQSEYC-----NVGNKTYLT-----NHPAKKYVFDFMRLLIMDNLCMTPASKQTPIIDLLLEASPERSTRTQQKEFQSYILDSVMEQLLAADVLMGEEASLPITTGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLVVDFIVQLITQSKRRSQGLSLDSVYHCLNRTILYQLSR------PHKTVPQQVTLLDSLRVLTVNRNLVLGPGNHDQEFVACLAHCLINLHTGSSVEGFGLEAEARMTTWHV--AVPSENESDSVQSQDVSEGRQLLLKAVNRVWTELMHSKRQMLEDIFKVSLPVNDRGHVDIGTARPALEEPAAKSWQNHLVHEK----------------------KCISRGETVAPANQS----KLSRVSSGFGLSKLTGSRRSKKESGMNK-----------NNLSAQETFQWMFTHIAVVRDLVAMQYKEHQERQQNALKYVMDEWAGIEYELLRERGLWGPPIGSHLDKFQLDMTEGPCRMRKKMVRNDMFYIHYPYVP-------DPEPNASTQKPARYRRAISYDSKEYY 2427 HSP 2 Score: 986.482 bits (2549), Expect = 0.000e+0 Identity = 459/769 (59.69%), Postives = 587/769 (76.33%), Query Frame = 2 Query: 8255 QWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVP 10561 Q + + ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P + +R S F++ +IREVHKRRYLLQP+A EVF GDGRN+LLAF K ++NK+Y +F+ V SL ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDL +P TFR L KPMGAQ+++RL Q++KR+++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG+KQNG LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ S N + P P+ ++ +++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK L+PP + + AWG++D S R+ NY+SDK + VYE +G I+C +C N +++ITGGFST + VW +GS+ + A +L+L+ L GH +AVTCL +++Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G +AS NT TGRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP Sbjct: 2504 QKTDNTTLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTVTREIRDIETLPPNMHEPIIPRGARQSKSQLKRTCS-IFAYEDIREVHKRRYLLQPMAAEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLA-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLNNPKTFRNLSKPMGAQTDDRLIQYKKRFKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGSKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---SKSNGEA-PGGPVTLNSTLDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLVPPAWNKTFAWGYADLSCRLSNYESDKAVVVYECLSEWGQILCAICPNPKLVITGGFSTAICVWE----------TGSSKEK-----AKSLTLKQALLGHTDAVTCLTASSAYHIVVSGSRDRTCIIWDLNKLSFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGSPVASANTFTGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRIEFLQVP 3237
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: wdfy4 (WDFY family member 4 [Source:ZFIN;Acc:ZDB-GENE-090313-322]) HSP 1 Score: 625.55 bits (1612), Expect = 0.000e+0 Identity = 321/709 (45.28%), Postives = 448/709 (63.19%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQN---SKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPH----PTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELK-NAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPI-STSFCSADFSEPQAVSSQP 10621 ++S+ +I+E + R+LL+ A+E+FL +G + L F Y + V SSL + ++ + K ++++ EK+V +W++GEISNF+YLM+LNTLAGR+YNDLMQYP+FPW++ADYESETLDL+SP+TFR L KPMGAQ+E R +F +RY E ++ G+ + HY THYSSA+IVA YLVRMEPF+Q FL+LQGG FD+ +RMFHSI++ WESAS+ NM+D++ELIPEFFYLP+FL N+N+FD G Q+G L D++LPPWAKGD +EFIR HREALE DYVS+ L+ WIDLIFGY+Q G AVEA+N FH FY D S+ DP+ +S ++G+INNFGQ+PKQ+F KPH P K + ++ QI P F+ LD ++PS Q VKE+ VGQI+ + VL VE+NK LIPP Y WG D + G+Y +K V E +G+ +C C N +IT G STVV VW++ ++ K + L+ LYGH + VTCL + ++++++SGS D+TCI+WDL + Y+ QL H++ V+A+ I+++TG + SCAGT+L+LW++ G+ LAS+NT IL + +WDP NV+ITG DGVVR+W EY +V + CS S+ +SS P Sbjct: 12 RWSYDDIKEANFMRFLLEDNALEIFLKNGTSVFLVFFNNDHVNAYKRLCSVVSSLKGRGETVLNVSRSGLLFVKTRRKTSAV------EKTVLIKWQRGEISNFEYLMHLNTLAGRTYNDLMQYPIFPWVIADYESETLDLSSPATFRDLSKPMGAQTEKRKEKFIQRYLEVENNDGDLSAQCHYCTHYSSAIIVASYLVRMEPFSQTFLQLQGGTFDVPERMFHSIQNEWESASKDNMSDVRELIPEFFYLPDFLVNSNQFDFGCMQDGTPLNDVVLPPWAKGDPQEFIRVHREALESDYVSSRLHLWIDLIFGYRQQGMPAVEALNTFHPYFYTDKHDRASMKDPVMKSTMLGYINNFGQMPKQIFTKPHASRTPNKSTAGKETSVSSQITP-------------FFFKLDKLKPSAQAVKEVSLGPVGQIVCKE-------------KDVLVVEKNKLLIPPQLNTYFCWGSYDQTCSFGSYTGEKSFGVCESLSDWGEPVCAACPNNSTIITAGTSTVVCVWDVFISKDK---------------LKHMRLKQTLYGHTDTVTCLVASEAHSMIISGSLDQTCILWDLEDLSYITQLPEHSSAVSALAINDLTGEIVSCAGTHLYLWTMKGQLLASINTYYEPEGNILCCCFTQKHEWDPRNVIITGSADGVVRIWKTEYTRVQLPGHEECSV--SQGHVLSSAP 671
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1]) HSP 1 Score: 424.476 bits (1090), Expect = 2.024e-118 Identity = 272/794 (34.26%), Postives = 403/794 (50.76%), Query Frame = 2 Query: 8291 GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK--RLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQP-VKELK--NAVGQ-------IIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASC-----AGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 + E I F RC + G LL G+S Y ++ N+P + H+ P T S +++ EI+EVHKR + L+ A+E+FL +GR LLAF K ++ +Y H+I + +E G+ S ++T W G+I+NF+YL +LN AGRS+NDLMQYPVFP+IL DY +ETLDL S +R L KP+ QS+ + ++ YR DDP PYHYG+HYS++ V +LVR+ PFT+ FL Q FD+ DR FHS+ TW +S +M D+KELIPEFFYLP FL N FD G +QN + + LPPWA+ D R FI HR+ALE D VS L +WIDL+FG KQ G AAV+A+NVFH Y G +D+ +++DP++R A+ I +GQ P+QLF H ++ L+ + + + + LA E+ D+ PS P +K LK VG + + +G ++ ++P+ + K + +Y++ ++WG++D LR+ + S+ I + + C + L TG V+ ++ + PT + Q +LYGH VT L V Y++L+S SRD TCI+WDL R+CY++ LSGH +PV A+ SE TG +A+ G+ L LW+I+G+ + V+ + I +V S + NV+ G +GVVR+WS Sbjct: 1874 ATSEPIRFTRRCVSVAPSRETAGELLLGKSGMYFVE-------------ENVP-ETHDNQSPHGET-------EPASFSWTYEEIKEVHKRWWQLRDNAMEIFLTNGRTLLLAFDNTKFRDDVY---------------HNILTSDLPNLLEYGNIS---------ALTHLWSSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILKDYTNETLDLQEASIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGKREDDPMPPVQPYHYGSHYSNSGTVLHFLVRLPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFSASHISRAGTKLLSEAELPAAMGLLVQLAFRESREQ----PRDSGYPSPLPWIKGLKWGEYVGSPSAPDPVVCFSQPHGERFGSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYTDNMLRLKSKQSEPPINFIQCSPLHQVSSCAWVPDSCQLFTGSKCGVITAYSNRFTTTMPTEM-------------EVESQVDLYGHTAEVTGLFVCKPYSILISVSRDGTCILWDLNRLCYVQSLSGHKSPVNAVSASETTGDIATVCDSVGGGSDLRLWTINGDLIGHVHC----REIICSVAFSNQPEGVSVNVIAGGLENGVVRLWS 2600
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1]) HSP 1 Score: 424.476 bits (1090), Expect = 2.321e-118 Identity = 272/794 (34.26%), Postives = 403/794 (50.76%), Query Frame = 2 Query: 8291 GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK--RLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQP-VKELK--NAVGQ-------IIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASC-----AGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 + E I F RC + G LL G+S Y ++ N+P + H+ P T S +++ EI+EVHKR + L+ A+E+FL +GR LLAF K ++ +Y H+I + +E G+ S ++T W G+I+NF+YL +LN AGRS+NDLMQYPVFP+IL DY +ETLDL S +R L KP+ QS+ + ++ YR DDP PYHYG+HYS++ V +LVR+ PFT+ FL Q FD+ DR FHS+ TW +S +M D+KELIPEFFYLP FL N FD G +QN + + LPPWA+ D R FI HR+ALE D VS L +WIDL+FG KQ G AAV+A+NVFH Y G +D+ +++DP++R A+ I +GQ P+QLF H ++ L+ + + + + LA E+ D+ PS P +K LK VG + + +G ++ ++P+ + K + +Y++ ++WG++D LR+ + S+ I + + C + L TG V+ ++ + PT + Q +LYGH VT L V Y++L+S SRD TCI+WDL R+CY++ LSGH +PV A+ SE TG +A+ G+ L LW+I+G+ + V+ + I +V S + NV+ G +GVVR+WS Sbjct: 1868 ATSEPIRFTRRCVSVAPSRETAGELLLGKSGMYFVE-------------ENVP-ETHDNQSPHGET-------EPASFSWTYEEIKEVHKRWWQLRDNAMEIFLTNGRTLLLAFDNTKFRDDVY---------------HNILTSDLPNLLEYGNIS---------ALTHLWSSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILKDYTNETLDLQEASIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGKREDDPMPPVQPYHYGSHYSNSGTVLHFLVRLPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFSASHISRAGTKLLSEAELPAAMGLLVQLAFRESREQ----PRDSGYPSPLPWIKGLKWGEYVGSPSAPDPVVCFSQPHGERFGSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYTDNMLRLKSKQSEPPINFIQCSPLHQVSSCAWVPDSCQLFTGSKCGVITAYSNRFTTTMPTEM-------------EVESQVDLYGHTAEVTGLFVCKPYSILISVSRDGTCILWDLNRLCYVQSLSGHKSPVNAVSASETTGDIATVCDSVGGGSDLRLWTINGDLIGHVHC----REIICSVAFSNQPEGVSVNVIAGGLENGVVRLWS 2594
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: nbeab (neurobeachin b [Source:ZFIN;Acc:ZDB-GENE-120329-2]) HSP 1 Score: 366.311 bits (939), Expect = 7.710e-105 Identity = 248/731 (33.93%), Postives = 364/731 (49.79%), Query Frame = 2 Query: 8516 MSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSI-DDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLI------------------------------PISIINKQIDP--MAPLASSAPAERLF----YHNLDNMEP----SLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMS----VNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSGHAAPVAA--ICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMW 10537 + K+ F EIR V RR+LLQ A+E+F+ + + + FP + K +V SL + G Q +I S ++TQRW++ EISNF+YLM+LNT+AGR+YNDL QYPVFPW+L ++ESE LDLT PS FR L KP+GA + R + RY WD+ ETPP HY THYS+A +LVR+EPFT FL G FD +R F SI +W Q + AD+KELIPEF+YLP N+N + LG++ +GV + D+ LP WAK +F+R +R ALE ++VS L++WIDLIFGYKQ G A A+NVFHHL YEG+V++ S+ DP R A I + GQ P QL +PHP + + P++ + P P + RLF +HN + SL+ L + +I A+ +GTN + + + + +C + RY+ GF D S RV + D+ KL ++ +G V CL + +++G + +W S + P S R A L GH V C++V A +++SG+++ C++ + G + LR L G + V IC+S + +SI+G+ LA + +I T + ++ D G ++TGG +GVV +W Sbjct: 337 LHGKWMFSEIRAVFTRRFLLQNTALEIFMANRTSVMFNFPDQPTVK------KVVYSLPCVGVGTSYGLPQARRISLASPR---QLFKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNFESEELDLTVPSNFRDLSKPIGALNPKRAVFYADRYESWDE---ETPPCHYTTHYSTANSTLHWLVRIEPFTTFFLNANGNKFDHPNRTFSSIARSWRHC-QRDTADVKELIPEFYYLPEMFVNSNGYCLGDRDDGVPVCDVELPAWAK-KPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAARALNVFHHLTYEGSVNLDSLASDPPLREATEAQIQSVGQSPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTLPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLEQAHHLPIEMDSLI-ANNSGTNKRQITDLVDQSIQI-NTQCFVVTADNRYILVCGFWDKSFRVYSSDTGKLTQIV-----FGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNNSDYPAPR------------AVLTGHDFEVVCVSVCAELGIIISGAKEGPCLVHTITGDL--LRALEGPDSCVLPRLICVSSEGHCIIYFDRGQFCSFSINGKLLAQM--------EINDSTRAIVLSSD-GQNLVTGGDNGVVEVW 1023
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:100496744]) HSP 1 Score: 2425.59 bits (6285), Expect = 0.000e+0 Identity = 1469/3872 (37.94%), Postives = 2167/3872 (55.97%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLE-SAEFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQP-GFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F ++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL V+ +L+ ++CM T S+PST +KCLY+FFDLP+ P+I + + P RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ NE+ +D+++ + LI LTT G EL+P L+ + + GF +P P K S+RN AF+VLQ+ FL A+T +L IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + K ++ I H+ IFK+V K++G+LE+ VN LH YA LK EQ ++ EQ +L L++++ LT+L+ + N +FR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L IVL+ESHR R VFRKV FV LV +E S + W+ + + ++ E + + LT A++ EP+N +F + Y L +AIR LGCF S + N S+NQ F+ L D + + V +L CS+ + ++Y A + FD H + + S P + MKL S+++ ++I+HP A++S++ L+ ++ D +Q H ++LQ+ I L L +RN Q+MCE+ + LL+ A+ NE+HPLH +FERLA+Q + P +R+FLRL DPL C S+ Y+P + + G G D FC R N G + LTRVK L+ +TT D + P+FVE + EGFGCLFLPS+AP + + + + G G R+FPP G ++STW C++ SS HP+RLL+L R S + CLNI ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL+ T KL+Y+ S + ++++VYAYIGT P ++S L WR GP HF+EE LTA+ V I LGPNY+G+FQ P D ++ GSL V EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HN+AGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ L KKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R D L+ +++ + +++ P I+ LS L++ S +DL RFGQF+ TL E + + NN+ LE +F + LI +RN ++LK+L S T + EEL+K LGFDW ++FM+ +H +TV AMR LV LLS P +L+F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQSLLP H +P +YF+L+ L L + +P+NL+ + P IS +N+S QF+ +S+ F+FG +SG+ +++ +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + + + +FL L +++P + D + S ++ F+ +S + +++E C M T L + PA+K + DF ++++++ L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GG+Y + NN++YF RVVDK+WQ + D +++ + +LISQ ++R ++ E++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G N G+ +TW+ P I D + + ++ + L L R +W E+ +KKQ+LE+ FK+ + ++ ++ P IE+ L+ W +++ E T+ +P S + S +++G +S KL RN L+ +++S +E W+ HI+VV++L+D + +++ + Y+ +W E EL RERGLWGP +GS LDKWML+ EGPCRMRKK++ N+ FY HYPY P + E+ + +++ A S D + D Y +L P N + TVEE+ + ++ +PE +T + ++G P+K D +D E++E M D + +E +S E ++ +DS+ ++ ++ EKI M+RCAR+QGLD EGLLLFG+ +FY++DGFT+ TREI +I +P+++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ IN + M+ L +++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STV+ VW + K A +L+L+ L GH + VTCL + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT GRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP + + AD E P + G E+ S+ E+ Q+ + S+ N S + + ++ + D SD+ S++++ D +DG V + N SKVQ ++S SQ +R + KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ + RN Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENEL-----------------PL-AERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDR----------------HVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPDDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENLQVSAPV-----------ISSRSNRSCQFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIP-------DAEHETNTMKPARYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGQEAQDDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3479
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:100496744]) HSP 1 Score: 2419.81 bits (6270), Expect = 0.000e+0 Identity = 1477/3892 (37.95%), Postives = 2175/3892 (55.88%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFD-----------NXXXXXXXXXXXXXXXXHYLKTIVSDSSF-IP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRP--YHRS---PCDNNENHCQ-VYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQP-GFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F ++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL V+ +L+ ++CM T S+PST +KCLY+FFDLP+ P+I + + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ NE+ +D+++ + LI LTT G EL+P L+ + + GF +P P K S+RN AF+VLQ+ FL A+T +L IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + K ++ I H+ IFK+V K++G+LE+ VN LH YA LK EQ ++ EQ +L L++++ LT+L+ + N +FR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L IVL+ESHR R VFRKV FV LV +E S + W+ + + ++ E + + LT A++ EP+N +F + Y L +AIR LGCF S + N S+NQ F+ L D + + V +L CS+ + ++Y A + FD N L K ++ VS SS P + MKL S+++ ++I+HP A++S++ L+ ++ D +Q H ++LQ+ I L L +RN Q+MCE+ + LL+ A+ NE+HPLH +FERLA+Q + P +R+FLRL DPL C S+ Y+P + + G G D FC R N G + LTRVK L+ +TT D + P+FVE + EGFGCLFLPS+AP + + + + G G R+FPP G ++STW C++ SS HP+RLL+L R S + CLNI ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL+ T KL+Y+ S + ++++VYAYIGT P ++S L WR GP HF+EE LTA+ V I LGPNY+G+FQ P D ++ GSL V EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HN+AGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ L KKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R D L+ +++ + +++ P I+ LS L++ S +DL RFGQF+ TL E + + NN+ LE +F + LI +RN ++LK+L S T + EEL+K LGFDW ++FM+ +H +TV AMR LV LLS P +L+F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQSLLP H +P +YF+L+ L L + +P+NL+ + P IS +N+S QF+ +S+ F+FG +SG+ +++ +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + + + +FL L +++P + D + S ++ F+ +S + +++E C M T L + PA+K + DF ++++++ L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GG+Y + NN++YF RVVDK+WQ + D +++ + +LISQ ++R ++ E++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G N G+ +TW+ P I D + + ++ + L L R +W E+ +KKQ+LE+ FK+ + ++ ++ P IE+ L+ W +++ E T+ +P S + S +++G +S KL RN L+ +++S +E W+ HI+VV++L+D + +++ + Y+ +W E EL RERGLWGP +GS LDKWML+ EGPCRMRKK++ N+ FY HYPY P H + C N C+ + Q +++ A S D + D Y +L P N + TVEE+ + ++ +PE +T + ++G P+K D +D E++E M D + +E +S E ++ +DS+ ++ ++ EKI M+RCAR+QGLD EGLLLFG+ +FY++DGFT+ TREI +I +P+++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ IN + M+ L +++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STV+ VW + K A +L+L+ L GH + VTCL + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT GRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP + + AD E P + G E+ S+ E+ Q+ + S+ N S + + ++ + D SD+ S++++ D +DG V + N SKVQ ++S SQ +R + KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ + RN Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENELP------------------LAERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDSRAEQIPPCLTNETSLPSPWGTPAVSRKRHVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPGADDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENLQVSAPV-----------ISSRSNRSCQFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIPDAEHETNTMVCFNKICSCKCIGQKSRYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGQEAQDDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3522
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:100496744]) HSP 1 Score: 2410.18 bits (6245), Expect = 0.000e+0 Identity = 1466/3884 (37.74%), Postives = 2159/3884 (55.59%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFD-----------NXXXXXXXXXXXXXXXXHYLKTIVSDSSF-IP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F ++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL V+ +L+ ++CM T S+PST +KCLY+FFDLP+ P+I + + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ NE+ +D+++ + LI LTT G EL+P L+ + + GF +P P K S+RN AF+VLQ+ FL A+T +L IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + K ++ I H+ IFK+V K++G+LE+ VN LH YA LK EQ ++ EQ +L L++++ LT+L+ + N +FR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L IVL+ESHR R VFRKV FV LV +E S + W+ + + ++ E + + LT A++ EP+N +F + Y L +AIR LGCF S + N S+NQ F+ L D + + V +L CS+ + ++Y A + FD N L K ++ VS SS P + MKL S+++ ++I+HP A++S++ L+ ++ D +Q H ++LQ+ I L L +RN Q+MCE+ + LL+ A+ NE+HPLH +FERLA+Q + P +R+FLRL DPL C S+ Y+P + + G G D FC R N G + LTRVK L+ +TT D + P+FVE + EGFGCLFLPS+AP + + + + G G R+FPP G ++STW C++ SS HP+RLL+L R S + CLNI ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL+ T KL+Y+ S + ++++VYAYIGT P ++S L WR GP HF+EE LTA+ V I LGPNY+G+FQ P D ++ GSL V EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HN+AGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ L KKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R D L+ +++ + +++ P I+ LS L++ S +DL RFGQF+ TL E + + NN+ LE +F + LI +RN ++LK+L S T + EEL+K LGFDW ++FM+ +H +TV AMR LV LLS P +L+F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQSLLP H +P +YF+L+ L L + +P+NL QF+ +S+ F+FG +SG+ +++ +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + + + +FL L +++P + D + S ++ F+ +S + +++E C M T L + PA+K + DF ++++++ L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GG+Y + NN++YF RVVDK+WQ + D +++ + +LISQ ++R ++ E++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G N G+ +TW+ P I D + + ++ + L L R +W E+ +KKQ+LE+ FK+ + ++ ++ P IE+ L+ W +++ E T+ +P S + S +++G +S KL RN L+ +++S +E W+ HI+VV++L+D + +++ + Y+ +W E EL RERGLWGP +GS LDKWML+ EGPCRMRKK++ N+ FY HYPY P + E+ + +++ A S D + D Y +L P N + TVEE+ + ++ +PE +T + ++G P+K D +D E++E M D + +E +S E ++ +DS+ ++ ++ EKI M+RCAR+QGLD EGLLLFG+ +FY++DGFT+ TREI +I +P+++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ IN + M+ L +++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STV+ VW + K A +L+L+ L GH + VTCL + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT GRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP + + AD E P + S+ E+ Q+ + S+ N S + + ++ + D SD+ S++++ D +DG V + N SKVQ ++S SQ +R + KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ + RN Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENELP------------------LAERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDSRAEQIPPCLTNETSLPSPWGTPAVSRKRHVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPGADDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENL-------------------------QFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIP-------DAEHETNTMKPARYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGLDCYDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3493
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: ENSXETT00000044622.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:7:37111747:37138184:1 gene:ENSXETG00000002289.1 transcript:ENSXETT00000044622.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 389.037 bits (998), Expect = 2.478e-118 Identity = 209/526 (39.73%), Postives = 307/526 (58.37%), Query Frame = 2 Query: 8975 MGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNM-EPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLE 10546 MGAQ+ R +F +RY++ ++ G+ + HY THYSSA IV+ YLVR+EPFTQ +QGG DLADR+FH++ WESAS NM+D++ELIPEF+YLP N+N LG Q+G V+GD+LLPPWA GD + F+R H EALE +YVS+ ++ WIDL+FGYKQ G AAV A+NVFH FY G+ D + DPL R+ +IGFI+NFGQ+PKQLF KPHP + K++ SS FY ++ + ++ P L+ AVG ++ + +V A E+N L+ P Y ++WG+SDGSL++ N ++ K++ V+E+ +G V+C + I+IT S+V+ VW S K S L L+ L GH AV C+ + Y +L+SGS D +CI+WDL + +R+L H V + +++ TG SC + L++WS++G+ L + + IL+ + +V++TG DG+VR W +E Sbjct: 1 MGAQTRERSQKFIQRYKDVENNDGDLSVQCHYCTHYSSASIVSSYLVRVEPFTQAMRWVQGGPLDLADRLFHNVAGVWESASSENMSDVRELIPEFYYLPEMFINSNHCQLGCMQDGTVVGDVLLPPWAHGDPQSFVRLHSEALESEYVSSQIHHWIDLVFGYKQRGPAAVHALNVFHPYFY-GSPDYLNSTDPLVRTTLIGFISNFGQVPKQLFTKPHPLRH--------GKEL-------SSGHTVSPFYSAPCSLKQVTVTPRGNLRGAVGHMLVTE-------------KAVFAAEKNHVLLSPSYAMSLSWGYSDGSLKLQNRNTRKVVDVWELMSHWGWCHSVICPSPAIVITAMSSSVLCVWIFSPPGQKERES-------------ELQLKKVLTGHGSAVLCVCASVKYGVLISGSADGSCILWDLDNLKCVRKLPIHPREVTLVAVNDRTGAFVSCCHSDLYMWSVNGKPLTYIRVGS----NILSCCFGGL------SVIVTGSQDGIVRFWKME 474
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: LYST (lysosomal trafficking regulator [Source:NCBI gene;Acc:779601]) HSP 1 Score: 417.927 bits (1073), Expect = 5.338e-116 Identity = 259/748 (34.63%), Postives = 390/748 (52.14%), Query Frame = 2 Query: 8450 IDVHEPIVPSTPTVNTFNHRRKMSDKF--SFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPH---PTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNM----EPSLQP-VKELK--NAVG-------QIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCA-----GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 I V + + P+ TF + F ++ EI+EVHKR + L+ AVE+FL +GR LLAF K+++ IY H+I + +E G+ + ++T W G+I+NF+YL +LN AGRS++DLMQYPVFP+IL+DY +ETLDL+ + +R L KP+ QS+ + ++ Y+ DDP PYHYG+HYS++ V +LVRM PFT+ FL Q FD+ DR FHS+K TW +S +M D+KELIPEFFYLP FL N FD G +QNG + + LPPWA+ D R FI HR+ALE D VS + WIDL+FGYKQ G AAV+A+NVFH Y G +D+ +++DP++R A+ I +GQ P+QLF H P +LL+ + P A + F + D PS P +K LK VG + + +G ++ ++P+ + K + +Y++ ++WG++D LR+ + S+ + + + + C + L TG V+ + S P L + Q +LYGH +T L V Y++L+S S+D TCI+WDL R+CY++ L+GH +PV A+ SE TG +A+ G+ L LW+++G+ + V+ + I +V S + NV+ G +G+VR+WS Sbjct: 2915 IRVTQRCINVAPSRETFGELLLEAASFAWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKIRDDIY---------------HNILNNNLPNLLEYGNIT---------ALTHLWCTGQITNFEYLTHLNKHAGRSFSDLMQYPVFPFILSDYFNETLDLSDSAIYRNLAKPIAVQSKEKEDRYIDNYKYLEDEYCKGDREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMKTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGLRQNGERVNHVNLPPWARNDPRLFILIHRQALESDNVSQTICHWIDLVFGYKQKGRAAVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFHSAHVSRPGSKLLMEGEL---------PAAMGLLVQLAFRDSRDTSRDVGHPSPLPWIKGLKWGEYVGSPSAPDPSVCFSQPHGERFGSLQALPTRAVCGLSGKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYADNILRLKSKQSEPPVNFIQCSELHQVTSCAWVPDSCQLFTGSKCGVITAYLNRFTNSTP-------------LEIEVESQVHLYGHTAEITSLFVCKPYSILISVSKDGTCIIWDLNRLCYVQSLTGHKSPVTAVSASETTGDIATVCDSVGGGSDLRLWTVNGDLIGHVHC----REIICSVAFSNQPEGVSVNVIAGGLENGIVRLWS 3611
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875]) HSP 1 Score: 1231.47 bits (3185), Expect = 0.000e+0 Identity = 883/2774 (31.83%), Postives = 1399/2774 (50.43%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKT-----------IVSDSSFIP----NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTY--------ISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE AG P RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ E +D+++ L+ L+ LTT G EL+P ++ + + GF +P P K S+RN AF VLQ+ FL A+T+FL IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + + + +K ++ H+ IFK+V +++G+LE+ VN LH YA LK A DS NN +Q L LL+++ LT+L+ + N +FR+ GG+ C ++V + + + AL I+ L LS E+DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E S K W+ + + ++LE + + LT AL+ EP+N +F + Y L +A+R LGCF SD+ I N N+Q + +E +VS+ D++ L CS+ + ++Y A + FD+ S T VS P +KL V S + + ++I+HP A+++++ L+ ++ Q H ++LQ+ + L L +RN Q+MCE+ + LL A+ +E+H LH +FERLA+Q + P +R+FLRLA PL C + S+ ++P + G G D F ++ S ++ G + LTRVK L+ +TT D + P+FVE + EGFGCLFLP + ++ ++ + ++ G+G GER FPP G S+S W C++ FSS HP+RLL++ R S + CL I ++++ + ++VSTKEE+ N E S A F C L+ E W HL L R GM+K+S+ + +L+GQL+ T KL+Y+ S + ++++VYAY+GT P +I++L WR GP HF+EE L S V+ I LGPNY+G+FQ P D + +P+ SLVAEEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HNAAGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L R + L P I+ LS L++ + N +DL RFGQF+ TL E + + NN+ + + L+ + + L + + + E + EEL++ LGFDWI++FM+ +HP+TV AMR LV LLS ++KF++G+ GWL TD VL + G +L N +REIN D+CH PGF+ LQS LP H +P +YF+L+AL L + +P+NL+ + P T S Q QF+ +S+ F+FG G +++ I +C+E+A +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + S+ + DFL L ++P + D + S ++ F+ ++ + +++E C + T L + PA+K + DF +++I+D L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GGSY + NN++YF RVVDK+WQ + + ++I ++ +LI+Q ++R ++ +++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G ++ G+ +TW+ PD + +I + Q+ +N +W E+ +KKQ+LEE FK+ + ++ P IE+ LK W +++ E + R +P + + S +++G +S KL RN L + S +E W+ HI+VV++L+D + +++ + Y+ +W +E EL RERGLWGP +GS LDKWML+ EGPCRMRKKM+ N+ FY HYPY P E V + +++ A S D + YY +L+ S NP V++ I + ++PE +T + ++G S P GD + ++ QD + I +E+E+T N Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPE-----------------AGGGAQNELPL-AERRGLLQKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQGKEAEC-RDALKDLVSLVTSLTTYGVSELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEALTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGEDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVSQSQVLELLHTVFCTLTAALRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAVNVFPSNTQPFQR------------LLEEGAVSV----DSV------SPTLRHCSK----------LFIYLYKVATDSFDSHAEQIPPCLTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTSSPLQSSDAVIIHPGAMLAMLDLLASVG-SVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCGAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSFEPEMRSSVITSLEGLGSDNVFSSHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLTDGAVVSGMGSGERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELVVEGQWHHLALLMSR-GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAVCVPCKDAKSEGVTPSPV-SLVAEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLVHNAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQ---GFPNS-NDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKPDPGAEEEFGGLVSANLILLRNRLLDILLKLVYTSKEKTNINLQACEELVRTLGFDWIMMFMEEHLHPTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFLVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVT-----------SSRCKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTESAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWLSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAG-SVEGFGLEAEARMTTWHIMIPSDIEPDGGYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVSLPVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCIS-----RGEALVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLHK-----------------------HSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVP-------ETEQEASVGKPARYRRAISYDSKEYYL--------------RLA-------SGNPAIVQDAIVESSEGEATQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSI--EEEEKTDN 2505 HSP 2 Score: 1184.47 bits (3063), Expect = 0.000e+0 Identity = 566/1044 (54.21%), Postives = 736/1044 (70.50%), Query Frame = 2 Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWIL+DY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ ++ N I + A ++++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STVV VW M + K A L+L+ L GH + VTC + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT TGRS+QI+ MS M +WD NV++TG +DGVVR W +E++QVP + + + E Q + + +SS+ E +E + + + S + + S A + D SD+ S++++ D +DG +N E + +Q L P + +L+ G+ W+RQL+FRSKLTMHTA++R DN +P+ +++L +S+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+YS+ ++ + RN Sbjct: 2511 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGIS----VPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEDLEMQEGCPEAQIGQQAQDDDSSDSETEEPSVSQDPKDTSSQPSSTSHRPRAASCRATATWCTDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQTRAHLQGPLAHPHPNPIEARSYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRN 3507
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875]) HSP 1 Score: 1225.31 bits (3169), Expect = 0.000e+0 Identity = 884/2787 (31.72%), Postives = 1401/2787 (50.27%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKT-----------IVSDSSFIP----NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTY--------ISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGN-----REQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRS--------PCDNNENHCQVYQIKK---FKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE AG P RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ E +D+++ L+ L+ LTT G EL+P ++ + + GF +P P K S+RN AF VLQ+ FL A+T+FL IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + + + +K ++ H+ IFK+V +++G+LE+ VN LH YA LK A DS NN +Q L LL+++ LT+L+ + N +FR+ GG+ C ++V + + + AL I+ L LS E+DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E S K W+ + + ++LE + + LT AL+ EP+N +F + Y L +A+R LGCF SD+ I N N+Q + +E +VS+ D++ L CS+ + ++Y A + FD+ S T VS P +KL V S + + ++I+HP A+++++ L+ ++ Q H ++LQ+ + L L +RN Q+MCE+ + LL A+ +E+H LH +FERLA+Q + P +R+FLRLA PL C + S+ ++P + G G D F ++ S ++ G + LTRVK L+ +TT D + P+FVE + EGFGCLFLP + ++ ++ + ++ G+G GER FPP G S+S W C++ FSS HP+RLL++ R S + CL I ++++ + ++VSTKEE+ N E+ ++ E C L+ E W HL L R GM+K+S+ + +L+GQL+ T KL+Y+ S + ++++VYAY+GT P +I++L WR GP HF+EE L S V+ I LGPNY+G+FQ P D + +P+ SLVAEEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HNAAGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L R + L P I+ LS L++ + N +DL RFGQF+ TL E + + NN+ + + L+ + + L + + + E + EEL++ LGFDWI++FM+ +HP+TV AMR LV LLS ++KF++G+ GWL TD VL + G +L N +REIN D+CH PGF+ LQS LP H +P +YF+L+AL L + +P+NL+ + P T S Q QF+ +S+ F+FG G +++ I +C+E+A +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + S+ + DFL L ++P + D + S ++ F+ ++ + +++E C + T L + PA+K + DF +++I+D L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GGSY + NN++YF RVVDK+WQ + + ++I ++ +LI+Q ++R ++ +++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G ++ G+ +TW+ PD + +I + Q+ +N +W E+ +KKQ+LEE FK+ + ++ P IE+ LK W +++ E + R +P + + S +++G +S KL RN L + S +E W+ HI+VV++L+D + +++ + Y+ +W +E EL RERGLWGP +GS LDKWML+ EGPCRMRKKM+ N+ FY HYPY P P E V KK ++ A S D + YY +L+ S NP V++ I + ++PE +T + ++G S P GD + ++ QD + I +E+E+T N Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPE-----------------AGGGAQNELPL-AERRGLLQKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQGKEAEC-RDALKDLVSLVTSLTTYGVSELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEALTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGEDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVSQSQVLELLHTVFCTLTAALRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAVNVFPSNTQPFQR------------LLEEGAVSV----DSV------SPTLRHCSK----------LFIYLYKVATDSFDSHAEQIPPCLTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTSSPLQSSDAVIIHPGAMLAMLDLLASV-GSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCGAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSFEPEMRSSVITSLEGLGSDNVFSSHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLTDGAVVSGMGSGERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFR--CGELVVEGQWHHLALLMSR-GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAVCVPCKDAKSEGVTPSPV-SLVAEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLVHNAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQ---GFPNS-NDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKPDPGAEEEFGGLVSANLILLRNRLLDILLKLVYTSKEKTNINLQACEELVRTLGFDWIMMFMEEHLHPTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFLVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVT-----------SSRCKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTESAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWLSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAG-SVEGFGLEAEARMTTWHIMIPSDIEPDGGYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVSLPVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCIS-----RGEALVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLHK-----------------------HSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQEASVGSEIPSKQPEPPDDVIAQKKPARYRRAISYDSKEYYL--------------RLA-------SGNPAIVQDAIVESSEGEATQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSI--EEEEKTDN 2523 HSP 2 Score: 1184.47 bits (3063), Expect = 0.000e+0 Identity = 566/1044 (54.21%), Postives = 736/1044 (70.50%), Query Frame = 2 Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWIL+DY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ ++ N I + A ++++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STVV VW M + K A L+L+ L GH + VTC + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT TGRS+QI+ MS M +WD NV++TG +DGVVR W +E++QVP + + + E Q + + +SS+ E +E + + + S + + S A + D SD+ S++++ D +DG +N E + +Q L P + +L+ G+ W+RQL+FRSKLTMHTA++R DN +P+ +++L +S+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+YS+ ++ + RN Sbjct: 2529 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGIS----VPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEDLEMQEGCPEAQIGQQAQDDDSSDSETEEPSVSQDPKDTSSQPSSTSHRPRAASCRATATWCTDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQTRAHLQGPLAHPHPNPIEARSYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRN 3525
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875]) HSP 1 Score: 1222.61 bits (3162), Expect = 0.000e+0 Identity = 878/2785 (31.53%), Postives = 1394/2785 (50.05%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKT-----------IVSDSSFIP----NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTY--------ISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGN-----REQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRS--------PCDNNENHCQVYQIKK---FKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ + AG P RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ E +D+++ L+ L+ LTT G EL+P ++ + + GF +P P K S+RN AF VLQ+ FL A+T+FL IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + + + +K ++ H+ IFK+V +++G+LE+ VN LH YA LK A DS NN +Q L LL+++ LT+L+ + N +FR+ GG+ C ++V + + + AL I+ L LS E+DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E S K W+ + + ++LE + + LT AL+ EP+N +F + Y L +A+R LGCF SD+ I N N+Q + +E +VS+ D++ L CS+ + ++Y A + FD+ S T VS P +KL V S + + ++I+HP A+++++ L+ ++ Q H ++LQ+ + L L +RN Q+MCE+ + LL A+ +E+H LH +FERLA+Q + P +R+FLRLA PL C + S+ ++P + G G D F ++ S ++ G + LTRVK L+ +TT D + P+FVE + EGFGCLFLP + ++ ++ + ++ G+G GER FPP G S+S W C++ FSS HP+RLL++ R S + CL I ++++ + ++VSTKEE+ N E+ ++ E C L+ E W HL L R GM+K+S+ + +L+GQL+ T KL+Y+ S + ++++VYAY+GT P +I++L WR GP HF+EE L S V+ I LGPNY+G+FQ P D + +P+ SLVAEEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HNAAGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L R + L P I+ LS L++ + N +DL RFGQF+ TL E + + NN+ + + L+ + + L + + + E + EEL++ LGFDWI++FM+ +HP+TV AMR LV LLS ++KF++G+ GWL TD VL + G +L N +REIN D+CH PGF+ LQS LP H +P +YF+L+AL L + +P+NL QF+ +S+ F+FG G +++ I +C+E+A +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + S+ + DFL L ++P + D + S ++ F+ ++ + +++E C + T L + PA+K + DF +++I+D L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GGSY + NN++YF RVVDK+WQ + + ++I ++ +LI+Q ++R ++ +++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G ++ G+ +TW+ PD + +I + Q+ +N +W E+ +KKQ+LEE FK+ + ++ P IE+ LK W +++ E + R +P + + S +++G +S KL RN L + S +E W+ HI+VV++L+D + +++ + Y+ +W +E EL RERGLWGP +GS LDKWML+ EGPCRMRKKM+ N+ FY HYPY P P E V KK ++ A S D + YY +L+ S NP V++ I + ++PE +T + ++G S P GD + ++ QD + I +E+E+T N Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPH----------------VPEAGGGAQNELPL-AERRGLLQKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQGKEAEC-RDALKDLVSLVTSLTTYGVSELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEALTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGEDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVSQSQVLELLHTVFCTLTAALRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAVNVFPSNTQPFQR------------LLEEGAVSV----DSV------SPTLRHCSK----------LFIYLYKVATDSFDSHAEQIPPCLTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTSSPLQSSDAVIIHPGAMLAMLDLLASV-GSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCGAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSFEPEMRSSVITSLEGLGSDNVFSSHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLTDGAVVSGMGSGERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFR--CGELVVEGQWHHLALLMSR-GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAVCVPCKDAKSEGVTPSPV-SLVAEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLVHNAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQ---GFPNS-NDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKPDPGAEEEFGGLVSANLILLRNRLLDILLKLVYTSKEKTNINLQACEELVRTLGFDWIMMFMEEHLHPTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFLVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENL-------------------------QFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTESAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWLSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAGSSVEGFGLEAEARMTTWHIMIPSDIEPDGGYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVSLPVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCIS-----RGEALVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLHK-----------------------HSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQEASVGSEIPSKQPEPPDDVIAQKKPARYRRAISYDSKEYYL--------------RLA-------SGNPAIVQDAIVESSEGEATQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSI--EEEEKTDN 2509 HSP 2 Score: 1184.47 bits (3063), Expect = 0.000e+0 Identity = 566/1044 (54.21%), Postives = 736/1044 (70.50%), Query Frame = 2 Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWIL+DY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ ++ N I + A ++++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STVV VW M + K A L+L+ L GH + VTC + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT TGRS+QI+ MS M +WD NV++TG +DGVVR W +E++QVP + + + E Q + + +SS+ E +E + + + S + + S A + D SD+ S++++ D +DG +N E + +Q L P + +L+ G+ W+RQL+FRSKLTMHTA++R DN +P+ +++L +S+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+YS+ ++ + RN Sbjct: 2515 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGIS----VPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEDLEMQEGCPEAQIGQQAQDDDSSDSETEEPSVSQDPKDTSSQPSSTSHRPRAASCRATATWCTDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQTRAHLQGPLAHPHPNPIEARSYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRN 3511
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy4 (WD repeat and FYVE domain containing 4 [Source:MGI Symbol;Acc:MGI:3584510]) HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0 Identity = 347/815 (42.58%), Postives = 490/815 (60.12%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG----EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVS 10639 + QV ++ ++ EK+ +QG V EG+LLFGQ +FYI + FTL T ++ ++ ++ +P + FN + + SD +S + ++RE+ + R+LLQ IA+E+F +G + LL F ++K F Q S+ G+ G+T N ++++ QRW+K EISNF+YLMYLNTLAGR+YND MQYPVFPW+LADY SE L+LT+P TFR L KPMGAQ++ R +F +R+++ + G+ T HY THYSSA+IVA YLVRM PFTQ F LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N + G Q+G LGD+ LPPWA GD R+FI HR+ALE D+VS++L+ WIDLIFGYKQ G AAVEAVN FH FY +D+ SI DPL +S ++GFI+NFGQ+PKQ+F KPHP++ K D P+ ++ F H+L + PS VK++ K A+G I+ + S+LAVE+NK L+PPL+ R +WGF D S +G+Y SDK++ +E +G +C +C + +++T G S VV +W +S+ +P L L+ LYGH +AVTCL + +++LLVSGS+DRTCI+WDL + + L H ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G I + WD +V+ITG DG+VR+W E V++P+ QAV +P E +S Sbjct: 2374 ERQVILQELL-DGEKVSQKVPMVIVQGHLVSEGILLFGQHHFYICENFTLSPTGDVYCTHHCLSNISDPFI--------FNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNSDRSKALKSFSTF--------QPSLKGK--------GTTEDPFNLRKHPGFDRTMLQRWQKREISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQTKERKLKFTQRFKDVEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKSTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGCMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLGSITDPLIKSTILGFISNFGQVPKQIFTKPHPSRNTTGKNPGPGK--DASTPVGLPGHSQS-FLHSLPALRPSQVTVKDMYLFSLGSESPKGAIGHIVPTE-------------KSILAVEKNKLLMPPLWNRTFSWGFDDFSCCLGSYGSDKILMTFENLAAWGPCLCAVCPSPTMIVTSGASAVVCIWELSLVKGRPR---------------GLKLRQALYGHTQAVTCLTASVTFSLLVSGSQDRTCILWDLDHLSRVACLPVHREGISAIAISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGTITCCCIVEGPAWDASHVIITGSKDGMVRIWKTEDVKMPVPR----------QAVMEEPSTEPLS 3122 HSP 2 Score: 322.783 bits (826), Expect = 3.061e-87 Identity = 279/1011 (27.60%), Postives = 470/1011 (46.49%), Query Frame = 2 Query: 2690 IIVHPEAVISLIHLIPAIRC-DQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLA----DPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVF---GNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGS---LVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEP---LSKLIELIISYSNK------PDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGW----LTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKE 5647 +I+HP + ++ L+P + D Q + E+Q + L L ++N Q+MCE+ M L+ + LHS+ + +FE+L +Q + P +R FL L + + + + + +C + GS ++ SQ +L SLI +T+ +N R A PSFVE +M EG+GCLF P+++ +S S+ + R FPP GG +FS W + + +++ HP+R L+L R L + + C +IS+ + ++VST+E+ F E E+ +E ++ + C LL W HL + + M ++ S + +L+GQ I + K+ YI S F + VY YIGT + S+L WR GP + EE ++A ++ I +LGP Y GNFQ L E+P G L+AEE+V F LY + SI ++ I YNE+D +IA+++++ ++ ++P+ ++ N AGHLSG R+LGA+ +G G+R F +P +D +GG +LLG++++A D +YA +K++ S L N ++ L H+ GY++++FLL+KK L+ RIF L++ + G+A+ F+ + N +F V+C+ LW + + L + H+ E Q R+ + +L LL L NEP LSK+ +I + DL R G F+++TL +E +I L+ + A + + I +RN +++ ++++S T+E K E++ LG DW LL +Q +HPST LA++ L+ LS P +FRDG+ W + G D+V MDN + +PA + C LPGF L L +H IP++Y ++ + L + + + +E Sbjct: 826 MIMHPGIICIMVRLLPRLYLEDHPQLSE--EIQCSVARHLLSLVKSEKNRQVMCEA-GMLRTLMTFCPRTLSTGGSDLHSILIRIFEKLGSQAIEPDVLRQFLGLGIRPPRSAAVKSLHLPPGHEDNPGCSGSCAATAEKPTDSSPRPGGSQALRPSWASQYSA-----TALQTTLSLISMTSPRN------------------LQPQRAALTPSFVEFDMSSEGYGCLFTPTLSTVMGTSTEHSISGGTGSGAP---------RPFPPPGGLTFSCWFLISRQANVMEGHPLRFLTLVRHLARTEQPFVCFSISLCMD-DLSLVVSTEEKEFQPLDAMEPEDEAEPSAGRQLQVR-CSQLLTCGQWYHLAVVVSKE-MKRNCSVTTYLDGQAIGSAKMLYIQALPGSFFSMDPSSFVDVYGYIGTPRVWKQKSSLTWRLGPAYLFEEDISADTLALIIKLGPRYCGNFQAVHLQGEDPDGEATPLIAEERVSFGLYVPSSSITSIMNIRNTYNEVDSRLIAKEMNISSRDNATPVFLLRNCAGHLSGPLRTLGAVAVGQLGVRVFHSSPAASSLDYIGGPAILLGLISLATDDHTMYAAMKVLHSVLTSN-AMCDYLMQHICGYQILAFLLRKKTSFLNHRIFQLILSVAGTAELGFRPSAVT----------------NMCIFQHVLCNFELWTN------TADNLELTLFSHLLEILQS-------PREGPRNAEVAHQAQLLPKLLFL---------------------FNEPSLALSKVSTIIAILGCQLKGHFNIQDLLRVGLFVIYTLKPSSVNERQICLD-GAQDPSRPAGSQTSGKAIWLRNQLLEMLFGVISSSQLHLTSELK--EQVFLSLGPDWFLLLLQGHLHPSTTTLALKLLLYFLSSPPLRGRFRDGLSAGCWVENCMDGVDIV---------MDNLKSRPAVPDQ---SPCLLPGFRVLNDFLAYHVLIPEVYLIVSSFFLQTPLTELTNGPRE 1732 HSP 3 Score: 157.918 bits (398), Expect = 2.520e-37 Identity = 162/684 (23.68%), Postives = 313/684 (45.76%), Query Frame = 2 Query: 272 FQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284 F+ + VS + +EI++ + E+A A Q LQ + + G +LL + +L+ + + ++ + LP+ ++CLY+FF P + D + G + F Q+L IC E L+ +L+ L +A+ C +S W++ VL+ I+ S S IQ++ + ++N++K L + E+ + + + +R+S ++ LL +F N +GY ++ + L++ E + LI L+ LTTCG EL+ + + YP +EGF+ + +++N AF VLQ++F A LC+++L AIKT++ +P N+F+LE F+E + K VQE L++ +V L YVP + ++ + ++K + T + +++ +R+ +++F ++ +D G+L + + QL A ++K + S V + + EL +++ + L+ +N + + G +V F+K + +L ++ L++ + +EE MS +G + S ++Q L + + E+ + FR F + L LEG + + + LE V L +++ AL +P N +F N + L E + LGCFG+ Sbjct: 89 FRSLQRLAEDVSDQLAQEIQQALAGKPAEQARAAAGQLLQ-----WKSDADQDGNLLLKSVYVLTGTDSETLGRVVDSGLPALLLQCLYLFFAFP---------VEKDDLLESDVQGQRM-----------------FVQMLLNICSESQGLEGLLSGSELQSLL--IATTCLREHSCLFWKQPTFCVLRAIS-KAQSPSVIQYLRTADCVRLSVQNLSKLADTLPAPEVSEAVSLILNFVRDSYPISSALLLEFENGEGYPLLLKVLLRYNGLTQGVVE-PHLEELIELVMWLTTCGRSELK----VFDSVTYPQLEGFKFHQEAS-GVTVKNLQAFQVLQNLFHRASDSVLCIQVLLAIKTMWAWNPRNFFLLEWTLQPISQFAEIIPLKPTPVQEHFFQLLETLVFKLLYVPHEVLAKVQRLIKESSELSCTLVALRSILRITASDRLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKECSPDVQDPERELTYVMLSTVVTLLQGSVRNAVVLKDHG-------MVPFIKIFLDDECYRGPSLSILEQLSVIN-AEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILETPKGHAAFRVSSGFNGLLSLLSDLEGSLQVPEVTTCGAVSPSQTLELVLHTLCVVSAALHLDPVNEHFFRSNGLFEKLAEDLCLLGCFGT 723 HSP 4 Score: 61.6178 bits (148), Expect = 3.020e-8 Identity = 62/279 (22.22%), Postives = 120/279 (43.01%), Query Frame = 2 Query: 5900 MCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHV-IDIILECDIENTTQEHMKQFQTVFMNSLTEHFM-----AVDILSGQNLPLPPGGSYANIPN--NIYYFFSRVVDKVWQENYVDDPDVIISYLCRLI-----SQGRKRQITQESLYRSFNRLILFRLSR 6697 +C E A +LL M++ ++NQ + + W + P ++L+ F+ L H + S DFL + +P +S N SP + + G S PA + + +F ++++ + N Q + +++ILE + T + + FQT + S + F + L G PLP + A +P+ ++ YF ++V+K++ + DP I+ ++ I + ++ +LY S N++IL LS+ Sbjct: 1755 LCIEGALLLLGMLKAIMNQ--PPAGSGDGAWEQTLPSSVLQ-FLRLVHRSYPQDSAWRTPDFLQTVAIITFPLETQKETTSESSRNTSSPGASAEASHAAEG------------FQASFQPHPALRQLREFMQVLLRELLLGGSNPKQWLPLEVILEASPDGATSQQKRDFQTEVLLSTMDIFQVPSGDGMPTLRGSKEPLPNAEAGA-VPSLASVSYFTQKLVEKIYSGVFSADPRHILLFITEHIIAVIENPSSQKDTVMSALYSSLNKVILHCLSK 2017
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy4 (WD repeat and FYVE domain containing 4 [Source:MGI Symbol;Acc:MGI:3584510]) HSP 1 Score: 647.121 bits (1668), Expect = 0.000e+0 Identity = 347/815 (42.58%), Postives = 490/815 (60.12%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG----EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVS 10639 + QV ++ ++ EK+ +QG V EG+LLFGQ +FYI + FTL T ++ ++ ++ +P + FN + + SD +S + ++RE+ + R+LLQ IA+E+F +G + LL F ++K F Q S+ G+ G+T N ++++ QRW+K EISNF+YLMYLNTLAGR+YND MQYPVFPW+LADY SE L+LT+P TFR L KPMGAQ++ R +F +R+++ + G+ T HY THYSSA+IVA YLVRM PFTQ F LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N + G Q+G LGD+ LPPWA GD R+FI HR+ALE D+VS++L+ WIDLIFGYKQ G AAVEAVN FH FY +D+ SI DPL +S ++GFI+NFGQ+PKQ+F KPHP++ K D P+ ++ F H+L + PS VK++ K A+G I+ + S+LAVE+NK L+PPL+ R +WGF D S +G+Y SDK++ +E +G +C +C + +++T G S VV +W +S+ +P L L+ LYGH +AVTCL + +++LLVSGS+DRTCI+WDL + + L H ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G I + WD +V+ITG DG+VR+W E V++P+ QAV +P E +S Sbjct: 2215 ERQVILQELL-DGEKVSQKVPMVIVQGHLVSEGILLFGQHHFYICENFTLSPTGDVYCTHHCLSNISDPFI--------FNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNSDRSKALKSFSTF--------QPSLKGK--------GTTEDPFNLRKHPGFDRTMLQRWQKREISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQTKERKLKFTQRFKDVEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKSTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGCMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLGSITDPLIKSTILGFISNFGQVPKQIFTKPHPSRNTTGKNPGPGK--DASTPVGLPGHSQS-FLHSLPALRPSQVTVKDMYLFSLGSESPKGAIGHIVPTE-------------KSILAVEKNKLLMPPLWNRTFSWGFDDFSCCLGSYGSDKILMTFENLAAWGPCLCAVCPSPTMIVTSGASAVVCIWELSLVKGRPR---------------GLKLRQALYGHTQAVTCLTASVTFSLLVSGSQDRTCILWDLDHLSRVACLPVHREGISAIAISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGTITCCCIVEGPAWDASHVIITGSKDGMVRIWKTEDVKMPVPR----------QAVMEEPSTEPLS 2963 HSP 2 Score: 295.434 bits (755), Expect = 5.451e-79 Identity = 237/803 (29.51%), Postives = 394/803 (49.07%), Query Frame = 2 Query: 3299 RFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVF---GNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGS---LVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEP---LSKLIELI------ISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGW----LTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKE 5647 R A PSFVE +M EG+GCLF P+++ +S S+ + R FPP GG +FS W + + +++ HP+R L+L R L + + C +IS+ + ++VST+E+ F E E+ +E ++ + C LL W HL + + M ++ S + +L+GQ I + K+ YI S F + VY YIGT + S+L WR GP + EE ++A ++ I +LGP Y GNFQ L E+P G L+AEE+V F LY + SI ++ I YNE+D +IA+++++ ++ ++P+ ++ N AGHLSG R+LGA+ +G G+R F +P +D +GG +LLG++++A D +YA +K++ S L N ++ L H+ GY++++FLL+KK L+ RIF L++ + G+A+ F+ + N +F V+C+ LW + + L + H+ E Q + R+ + +L LL L NEP LSK+ +I + DL R G F+++TL +E +I L+ + A + + I +RN +++ ++++S T+E + E++ LG DW LL +Q +HPST LA++ L+ LS P +FRDG+ W + G D+V MDN + +PA + C LPGF L L +H IP++Y ++ + L + + + +E Sbjct: 963 RAALTPSFVEFDMSSEGYGCLFTPTLSTVMGTSTEHSISGGTGSGAP---------RPFPPPGGLTFSCWFLISRQANVMEGHPLRFLTLVRHLARTEQPFVCFSISLCMD-DLSLVVSTEEKEFQPLDAMEPEDEAEPSAGRQLQVR-CSQLLTCGQWYHLAVVVSKE-MKRNCSVTTYLDGQAIGSAKMLYIQALPGSFFSMDPSSFVDVYGYIGTPRVWKQKSSLTWRLGPAYLFEEDISADTLALIIKLGPRYCGNFQAVHLQGEDPDGEATPLIAEERVSFGLYVPSSSITSIMNIRNTYNEVDSRLIAKEMNISSRDNATPVFLLRNCAGHLSGPLRTLGAVAVGQLGVRVFHSSPAASSLDYIGGPAILLGLISLATDDHTMYAAMKVLHSVLTSN-AMCDYLMQHICGYQILAFLLRKKTSFLNHRIFQLILSVAGTAELGFRPSAVT----------------NMCIFQHVLCNFELWTN------TADNLELTLFSHLLEILQSPREGP-------RNAEVAHQAQLLPKLLFL---------------------FNEPSLALSKVSTIIAILGCQLKGHFNIQDLLRVGLFVIYTLKPSSVNERQICLD-GAQDPSRPAGSQTSGKAIWLRNQLLEMLFGVISSSQLHLTSE--LKEQVFLSLGPDWFLLLLQGHLHPSTTTLALKLLLYFLSSPPLRGRFRDGLSAGCWVENCMDGVDIV---------MDNLKSRPAVPDQ---SPCLLPGFRVLNDFLAYHVLIPEVYLIVSSFFLQTPLTELTNGPRE 1687 HSP 3 Score: 155.221 bits (391), Expect = 1.597e-36 Identity = 162/684 (23.68%), Postives = 313/684 (45.76%), Query Frame = 2 Query: 272 FQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284 F+ + VS + +EI++ + E+A A Q LQ + + G +LL + +L+ + + ++ + LP+ ++CLY+FF P + D + G + F Q+L IC E L+ +L+ L +A+ C +S W++ VL+ I+ S S IQ++ + ++N++K L + E+ + + + +R+S ++ LL +F N +GY ++ + L++ E + LI L+ LTTCG EL+ + + YP +EGF+ + +++N AF VLQ++F A LC+++L AIKT++ +P N+F+LE F+E + K VQE L++ +V L YVP + ++ + ++K + T + +++ +R+ +++F ++ +D G+L + + QL A ++K + S V + + EL +++ + L+ +N + + G +V F+K + +L ++ L++ + +EE MS +G + S ++Q L + + E+ + FR F + L LEG + + + LE V L +++ AL +P N +F N + L E + LGCFG+ Sbjct: 89 FRSLQRLAEDVSDQLAQEIQQALAGKPAEQARAAAGQLLQ-----WKSDADQDGNLLLKSVYVLTGTDSETLGRVVDSGLPALLLQCLYLFFAFP---------VEKDDLLESDVQGQRM-----------------FVQMLLNICSESQGLEGLLSGSELQSLL--IATTCLREHSCLFWKQPTFCVLRAIS-KAQSPSVIQYLRTADCVRLSVQNLSKLADTLPAPEVSEAVSLILNFVRDSYPISSALLLEFENGEGYPLLLKVLLRYNGLTQGVVE-PHLEELIELVMWLTTCGRSELK----VFDSVTYPQLEGFKFHQEAS-GVTVKNLQAFQVLQNLFHRASDSVLCIQVLLAIKTMWAWNPRNFFLLEWTLQPISQFAEIIPLKPTPVQEHFFQLLETLVFKLLYVPHEVLAKVQRLIKESSELSCTLVALRSILRITASDRLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKECSPDVQDPERELTYVMLSTVVTLLQGSVRNAVVLKDHG-------MVPFIKIFLDDECYRGPSLSILEQLSVIN-AEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILETPKGHAAFRVSSGFNGLLSLLSDLEGSLQVPEVTTCGAVSPSQTLELVLHTLCVVSAALHLDPVNEHFFRSNGLFEKLAEDLCLLGCFGT 723
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q8IZQ1|WDFY3_HUMAN (WD repeat and FYVE domain-containing protein 3 OS=Homo sapiens OX=9606 GN=WDFY3 PE=1 SV=2) HSP 1 Score: 1237.25 bits (3200), Expect = 0.000e+0 Identity = 890/2784 (31.97%), Postives = 1405/2784 (50.47%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXX------------XXXXXXXXXXXXHYLKTIVSDSSFIPN---PMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD----------FCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKI--AEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRS--------PCDNNENHCQVYQIK--KFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE Q + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ E+ +D+++ L+ LI LTT G EL+P ++ + + GF +P P K S+RN AF VLQ+ FL A+T FL IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + + + +K ++ H+ IFK+V +++G+LE+ VN LH YA LK A DS NN +Q L LL+++ LT+L+ + N +FR+ GG+ C ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E S K W+ + + ++ E + + LT A++ EP+N +F + Y L +A+R LGCF SD+ I N N+Q + L D SVS L CS+ + ++Y A + FD+R S +H ++ + + P +KL V SS+ + ++I+HP A+++++ L+ ++ Q H ++LQ+ + L L +RN Q+MCE+ + LL A+ +E+H LH +FERLA+Q + P +R+FLRLA PL C + S+ Y+P + G G D + S ++ G + LTRVK L+ +TT D + P+FVE + EGFGCLFLP + ++ ++ I+ ++ GIG GER FPP G S+S+W C++ FSS HP+RLL++ R S + CL I ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL++T KL+Y+ S + ++++VYAYIGT P +I++L WR GP HF+EE L +S V+ I LGPNY+G+FQ P D + +P+ SLV EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P+++IHN+AGHL+G+ R++GA LIGY G+R F P P+ + VGG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L R + L P I+ LS L++ S +DL RFGQF+ TL E + + NN+ L++ EF + I + + + + E + EEL+K LGFDWI++FM+ +H +TV AMR LV LLS ++KF++G+ GWL TD VL + G +L N +REIN D+CH PGF LQS LP H +P +YF+L+AL L + +P+NL+ + P ISC + Q QF+ +S+ F+FG G +++ I +C+EA +LL M+R ML E +W+R+YP+TL++FF YLYH+ + S+ M DFL L ++P + D + S ++ F+ ++ + +++E C + T L + PA+K + DF +++I+D L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GGSY + NN++YF RVVDK+WQ + + ++I ++ +LI+Q ++R ++ +++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G N+ G+ +TW+ PD + +I + Q+ +N +W E+ +KKQ+LEE FK+ + ++ + P IE+ LK W +++ E I+ G ++ + Q KL+R+S L +L+ S SG + +S +E W+ HI+VV++L+D + +++ + Y+ +W +E EL RERGLWGP +GS LDKWML+ EGPCRMRKKM+ N+ FY HYPY P P E + Q K +++ A S D + Y Y +L+ S NP V++ I + ++PE +T + ++G S P GD + ++ QD + I +E+E+T N Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELP------------------LAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAES-KDALKDLVNLITSLTTYGVSELKPA-GITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAMNVFPSNTQP-------FQRLLEEDVISIESVS---------------PTLRHCSK----------LFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASV-GSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPV-SLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQGFPS----SNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPV-----------ISCRSKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTEAVFLLLGMLRSMLTSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEK----------------------KCISRGEALAPTTQS----KLSRVSSGFGLSKLTGSRRNRKESGLNK-----------HSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEY--------------YMRLA-------SGNPAIVQDAIVESSEGEAAQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSI--EEEEKTDN 2523 HSP 2 Score: 1193.33 bits (3086), Expect = 0.000e+0 Identity = 571/1049 (54.43%), Postives = 740/1049 (70.54%), Query Frame = 2 Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDE----YDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRP----NMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ ++ N I + + ++++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STVV VW M + K A ++L+ L GH + VTC + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT TGRS+QI+ MS M +WD NV++TG +DGVVR W +E++QVP + + A+ E Q + + +SS+ E DE D ++ S ++ + A+ R+ A D+ S ++ S+ +DG V + + ++ L LS P P N +L+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ S RN Sbjct: 2529 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLP----GSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAAS-CRATAAWCTDSGSDDSRRWSDQL---------------SLDEKDGFIFVNYSEG-QTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRN 3525
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q6VNB8|WDFY3_MOUSE (WD repeat and FYVE domain-containing protein 3 OS=Mus musculus OX=10090 GN=Wdfy3 PE=1 SV=1) HSP 1 Score: 1231.47 bits (3185), Expect = 0.000e+0 Identity = 883/2774 (31.83%), Postives = 1399/2774 (50.43%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKT-----------IVSDSSFIP----NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTY--------ISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE AG P RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ E +D+++ L+ L+ LTT G EL+P ++ + + GF +P P K S+RN AF VLQ+ FL A+T+FL IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + + + +K ++ H+ IFK+V +++G+LE+ VN LH YA LK A DS NN +Q L LL+++ LT+L+ + N +FR+ GG+ C ++V + + + AL I+ L LS E+DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E S K W+ + + ++LE + + LT AL+ EP+N +F + Y L +A+R LGCF SD+ I N N+Q + +E +VS+ D++ L CS+ + ++Y A + FD+ S T VS P +KL V S + + ++I+HP A+++++ L+ ++ Q H ++LQ+ + L L +RN Q+MCE+ + LL A+ +E+H LH +FERLA+Q + P +R+FLRLA PL C + S+ ++P + G G D F ++ S ++ G + LTRVK L+ +TT D + P+FVE + EGFGCLFLP + ++ ++ + ++ G+G GER FPP G S+S W C++ FSS HP+RLL++ R S + CL I ++++ + ++VSTKEE+ N E S A F C L+ E W HL L R GM+K+S+ + +L+GQL+ T KL+Y+ S + ++++VYAY+GT P +I++L WR GP HF+EE L S V+ I LGPNY+G+FQ P D + +P+ SLVAEEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HNAAGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L R + L P I+ LS L++ + N +DL RFGQF+ TL E + + NN+ + + L+ + + L + + + E + EEL++ LGFDWI++FM+ +HP+TV AMR LV LLS ++KF++G+ GWL TD VL + G +L N +REIN D+CH PGF+ LQS LP H +P +YF+L+AL L + +P+NL+ + P T S Q QF+ +S+ F+FG G +++ I +C+E+A +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + S+ + DFL L ++P + D + S ++ F+ ++ + +++E C + T L + PA+K + DF +++I+D L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GGSY + NN++YF RVVDK+WQ + + ++I ++ +LI+Q ++R ++ +++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G ++ G+ +TW+ PD + +I + Q+ +N +W E+ +KKQ+LEE FK+ + ++ P IE+ LK W +++ E + R +P + + S +++G +S KL RN L + S +E W+ HI+VV++L+D + +++ + Y+ +W +E EL RERGLWGP +GS LDKWML+ EGPCRMRKKM+ N+ FY HYPY P E V + +++ A S D + YY +L+ S NP V++ I + ++PE +T + ++G S P GD + ++ QD + I +E+E+T N Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPE-----------------AGGGAQNELPL-AERRGLLQKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQGKEAEC-RDALKDLVSLVTSLTTYGVSELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEALTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGEDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVSQSQVLELLHTVFCTLTAALRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAVNVFPSNTQPFQR------------LLEEGAVSV----DSV------SPTLRHCSK----------LFIYLYKVATDSFDSHAEQIPPCLTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTSSPLQSSDAVIIHPGAMLAMLDLLASVG-SVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCGAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSFEPEMRSSVITSLEGLGSDNVFSSHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLTDGAVVSGMGSGERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELVVEGQWHHLALLMSR-GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAVCVPCKDAKSEGVTPSPV-SLVAEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLVHNAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQ---GFPNS-NDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKPDPGAEEEFGGLVSANLILLRNRLLDILLKLVYTSKEKTNINLQACEELVRTLGFDWIMMFMEEHLHPTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFLVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVT-----------SSRCKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTESAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWLSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAG-SVEGFGLEAEARMTTWHIMIPSDIEPDGGYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVSLPVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCIS-----RGEALVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLHK-----------------------HSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVP-------ETEQEASVGKPARYRRAISYDSKEYYL--------------RLA-------SGNPAIVQDAIVESSEGEATQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSI--EEEEKTDN 2505 HSP 2 Score: 1184.47 bits (3063), Expect = 0.000e+0 Identity = 566/1044 (54.21%), Postives = 736/1044 (70.50%), Query Frame = 2 Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWIL+DY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ ++ N I + A ++++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STVV VW M + K A L+L+ L GH + VTC + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT TGRS+QI+ MS M +WD NV++TG +DGVVR W +E++QVP + + + E Q + + +SS+ E +E + + + S + + S A + D SD+ S++++ D +DG +N E + +Q L P + +L+ G+ W+RQL+FRSKLTMHTA++R DN +P+ +++L +S+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+YS+ ++ + RN Sbjct: 2511 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGIS----VPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEDLEMQEGCPEAQIGQQAQDDDSSDSETEEPSVSQDPKDTSSQPSSTSHRPRAASCRATATWCTDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQTRAHLQGPLAHPHPNPIEARSYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRN 3507
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|E9Q2M9|WDFY4_MOUSE (WD repeat- and FYVE domain-containing protein 4 OS=Mus musculus OX=10090 GN=Wdfy4 PE=1 SV=2) HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0 Identity = 347/815 (42.58%), Postives = 490/815 (60.12%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG----EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVS 10639 + QV ++ ++ EK+ +QG V EG+LLFGQ +FYI + FTL T ++ ++ ++ +P + FN + + SD +S + ++RE+ + R+LLQ IA+E+F +G + LL F ++K F Q S+ G+ G+T N ++++ QRW+K EISNF+YLMYLNTLAGR+YND MQYPVFPW+LADY SE L+LT+P TFR L KPMGAQ++ R +F +R+++ + G+ T HY THYSSA+IVA YLVRM PFTQ F LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N + G Q+G LGD+ LPPWA GD R+FI HR+ALE D+VS++L+ WIDLIFGYKQ G AAVEAVN FH FY +D+ SI DPL +S ++GFI+NFGQ+PKQ+F KPHP++ K D P+ ++ F H+L + PS VK++ K A+G I+ + S+LAVE+NK L+PPL+ R +WGF D S +G+Y SDK++ +E +G +C +C + +++T G S VV +W +S+ +P L L+ LYGH +AVTCL + +++LLVSGS+DRTCI+WDL + + L H ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G I + WD +V+ITG DG+VR+W E V++P+ QAV +P E +S Sbjct: 2374 ERQVILQELL-DGEKVSQKVPMVIVQGHLVSEGILLFGQHHFYICENFTLSPTGDVYCTHHCLSNISDPFI--------FNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNSDRSKALKSFSTF--------QPSLKGK--------GTTEDPFNLRKHPGFDRTMLQRWQKREISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQTKERKLKFTQRFKDVEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKSTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGCMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLGSITDPLIKSTILGFISNFGQVPKQIFTKPHPSRNTTGKNPGPGK--DASTPVGLPGHSQS-FLHSLPALRPSQVTVKDMYLFSLGSESPKGAIGHIVPTE-------------KSILAVEKNKLLMPPLWNRTFSWGFDDFSCCLGSYGSDKILMTFENLAAWGPCLCAVCPSPTMIVTSGASAVVCIWELSLVKGRPR---------------GLKLRQALYGHTQAVTCLTASVTFSLLVSGSQDRTCILWDLDHLSRVACLPVHREGISAIAISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGTITCCCIVEGPAWDASHVIITGSKDGMVRIWKTEDVKMPVPR----------QAVMEEPSTEPLS 3122 HSP 2 Score: 322.783 bits (826), Expect = 2.141e-86 Identity = 279/1011 (27.60%), Postives = 470/1011 (46.49%), Query Frame = 2 Query: 2690 IIVHPEAVISLIHLIPAIRC-DQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLA----DPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVF---GNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGS---LVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEP---LSKLIELIISYSNK------PDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGW----LTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKE 5647 +I+HP + ++ L+P + D Q + E+Q + L L ++N Q+MCE+ M L+ + LHS+ + +FE+L +Q + P +R FL L + + + + + +C + GS ++ SQ +L SLI +T+ +N R A PSFVE +M EG+GCLF P+++ +S S+ + R FPP GG +FS W + + +++ HP+R L+L R L + + C +IS+ + ++VST+E+ F E E+ +E ++ + C LL W HL + + M ++ S + +L+GQ I + K+ YI S F + VY YIGT + S+L WR GP + EE ++A ++ I +LGP Y GNFQ L E+P G L+AEE+V F LY + SI ++ I YNE+D +IA+++++ ++ ++P+ ++ N AGHLSG R+LGA+ +G G+R F +P +D +GG +LLG++++A D +YA +K++ S L N ++ L H+ GY++++FLL+KK L+ RIF L++ + G+A+ F+ + N +F V+C+ LW + + L + H+ E Q R+ + +L LL L NEP LSK+ +I + DL R G F+++TL +E +I L+ + A + + I +RN +++ ++++S T+E K E++ LG DW LL +Q +HPST LA++ L+ LS P +FRDG+ W + G D+V MDN + +PA + C LPGF L L +H IP++Y ++ + L + + + +E Sbjct: 826 MIMHPGIICIMVRLLPRLYLEDHPQLSE--EIQCSVARHLLSLVKSEKNRQVMCEA-GMLRTLMTFCPRTLSTGGSDLHSILIRIFEKLGSQAIEPDVLRQFLGLGIRPPRSAAVKSLHLPPGHEDNPGCSGSCAATAEKPTDSSPRPGGSQALRPSWASQYSA-----TALQTTLSLISMTSPRN------------------LQPQRAALTPSFVEFDMSSEGYGCLFTPTLSTVMGTSTEHSISGGTGSGAP---------RPFPPPGGLTFSCWFLISRQANVMEGHPLRFLTLVRHLARTEQPFVCFSISLCMD-DLSLVVSTEEKEFQPLDAMEPEDEAEPSAGRQLQVR-CSQLLTCGQWYHLAVVVSKE-MKRNCSVTTYLDGQAIGSAKMLYIQALPGSFFSMDPSSFVDVYGYIGTPRVWKQKSSLTWRLGPAYLFEEDISADTLALIIKLGPRYCGNFQAVHLQGEDPDGEATPLIAEERVSFGLYVPSSSITSIMNIRNTYNEVDSRLIAKEMNISSRDNATPVFLLRNCAGHLSGPLRTLGAVAVGQLGVRVFHSSPAASSLDYIGGPAILLGLISLATDDHTMYAAMKVLHSVLTSN-AMCDYLMQHICGYQILAFLLRKKTSFLNHRIFQLILSVAGTAELGFRPSAVT----------------NMCIFQHVLCNFELWTN------TADNLELTLFSHLLEILQS-------PREGPRNAEVAHQAQLLPKLLFL---------------------FNEPSLALSKVSTIIAILGCQLKGHFNIQDLLRVGLFVIYTLKPSSVNERQICLD-GAQDPSRPAGSQTSGKAIWLRNQLLEMLFGVISSSQLHLTSELK--EQVFLSLGPDWFLLLLQGHLHPSTTTLALKLLLYFLSSPPLRGRFRDGLSAGCWVENCMDGVDIV---------MDNLKSRPAVPDQ---SPCLLPGFRVLNDFLAYHVLIPEVYLIVSSFFLQTPLTELTNGPRE 1732 HSP 3 Score: 157.918 bits (398), Expect = 1.763e-36 Identity = 162/684 (23.68%), Postives = 313/684 (45.76%), Query Frame = 2 Query: 272 FQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284 F+ + VS + +EI++ + E+A A Q LQ + + G +LL + +L+ + + ++ + LP+ ++CLY+FF P + D + G + F Q+L IC E L+ +L+ L +A+ C +S W++ VL+ I+ S S IQ++ + ++N++K L + E+ + + + +R+S ++ LL +F N +GY ++ + L++ E + LI L+ LTTCG EL+ + + YP +EGF+ + +++N AF VLQ++F A LC+++L AIKT++ +P N+F+LE F+E + K VQE L++ +V L YVP + ++ + ++K + T + +++ +R+ +++F ++ +D G+L + + QL A ++K + S V + + EL +++ + L+ +N + + G +V F+K + +L ++ L++ + +EE MS +G + S ++Q L + + E+ + FR F + L LEG + + + LE V L +++ AL +P N +F N + L E + LGCFG+ Sbjct: 89 FRSLQRLAEDVSDQLAQEIQQALAGKPAEQARAAAGQLLQ-----WKSDADQDGNLLLKSVYVLTGTDSETLGRVVDSGLPALLLQCLYLFFAFP---------VEKDDLLESDVQGQRM-----------------FVQMLLNICSESQGLEGLLSGSELQSLL--IATTCLREHSCLFWKQPTFCVLRAIS-KAQSPSVIQYLRTADCVRLSVQNLSKLADTLPAPEVSEAVSLILNFVRDSYPISSALLLEFENGEGYPLLLKVLLRYNGLTQGVVE-PHLEELIELVMWLTTCGRSELK----VFDSVTYPQLEGFKFHQEAS-GVTVKNLQAFQVLQNLFHRASDSVLCIQVLLAIKTMWAWNPRNFFLLEWTLQPISQFAEIIPLKPTPVQEHFFQLLETLVFKLLYVPHEVLAKVQRLIKESSELSCTLVALRSILRITASDRLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKECSPDVQDPERELTYVMLSTVVTLLQGSVRNAVVLKDHG-------MVPFIKIFLDDECYRGPSLSILEQLSVIN-AEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILETPKGHAAFRVSSGFNGLLSLLSDLEGSLQVPEVTTCGAVSPSQTLELVLHTLCVVSAALHLDPVNEHFFRSNGLFEKLAEDLCLLGCFGT 723 HSP 4 Score: 61.6178 bits (148), Expect = 2.113e-7 Identity = 62/279 (22.22%), Postives = 120/279 (43.01%), Query Frame = 2 Query: 5900 MCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHV-IDIILECDIENTTQEHMKQFQTVFMNSLTEHFM-----AVDILSGQNLPLPPGGSYANIPN--NIYYFFSRVVDKVWQENYVDDPDVIISYLCRLI-----SQGRKRQITQESLYRSFNRLILFRLSR 6697 +C E A +LL M++ ++NQ + + W + P ++L+ F+ L H + S DFL + +P +S N SP + + G S PA + + +F ++++ + N Q + +++ILE + T + + FQT + S + F + L G PLP + A +P+ ++ YF ++V+K++ + DP I+ ++ I + ++ +LY S N++IL LS+ Sbjct: 1755 LCIEGALLLLGMLKAIMNQ--PPAGSGDGAWEQTLPSSVLQ-FLRLVHRSYPQDSAWRTPDFLQTVAIITFPLETQKETTSESSRNTSSPGASAEASHAAEG------------FQASFQPHPALRQLREFMQVLLRELLLGGSNPKQWLPLEVILEASPDGATSQQKRDFQTEVLLSTMDIFQVPSGDGMPTLRGSKEPLPNAEAGA-VPSLASVSYFTQKLVEKIYSGVFSADPRHILLFITEHIIAVIENPSSQKDTVMSALYSSLNKVILHCLSK 2017
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q6ZS81|WDFY4_HUMAN (WD repeat- and FYVE domain-containing protein 4 OS=Homo sapiens OX=9606 GN=WDFY4 PE=1 SV=3) HSP 1 Score: 642.114 bits (1655), Expect = 0.000e+0 Identity = 335/788 (42.51%), Postives = 479/788 (60.79%), Query Frame = 2 Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG-EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQID-PMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPI 10564 + QV ++ ++ EK+ F +QG V EG+LLFG +FYI + FTL T ++ + ++ +P + FN + + +D +S + ++RE+ + R+LLQ IA+E+F +G + L F ++K + F SL K + T + G ++ + Q+W+K +ISNF+YLMYLNT AGR+ ND MQYPVFPW+LADY SETL+L +P FR L KPMGAQ++ R +F +R++E + G+ T HY THYSSA+IVA YLVRM PFTQ F LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N + G Q+G VLGD+ LPPWA GD R+FI HR+ALE D+VSA+L+ WIDLIFGYKQ G AAV+AVN+FH FY +D+ SI DPL +S ++GF++NFGQ+PKQLF KPHP R + K + P++ P F+++L ++ PS VK++ K A+G I+ S ++LAVE+NK L+PPL+ R +WGF D S +G+Y SDK++ +E +G +C +C + ++T G STVV VW +S+ +P L L+ LYGH +AVTCLA + +++LLVSGS+D TCI+WDL + ++ +L H ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G I + WD ++ITG DG+VR+W E V++ + Sbjct: 2376 ERQVILQELL-DKEKVTQKFSLVIVQGHLVSEGVLLFGHQHFYICENFTLSPTGDVYCTRHCLSNISDPFI--------FNLCSKDRSTDHYSCQCHSYADMRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQPSL-------------KGKATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLPEFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPA-RTAAGKPLPGKDVSTPVSLPGHPQP----FFYSLQSLRPSQVTVKDMYLFSLGSESPKGAIGHIV-------------STEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCLCAVCPSPTTIVTSGTSTVVCVWELSMTKGRPR---------------GLRLRQALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSV 3108 HSP 2 Score: 325.094 bits (832), Expect = 3.576e-87 Identity = 273/1007 (27.11%), Postives = 475/1007 (47.17%), Query Frame = 2 Query: 2687 SIIVHPEAVISLIHLIPAI-RCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISL----TRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHV-ILVSTKEEVFGNRE--QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMG-TLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPIL---DYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINP--LNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWL----TGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKET 5650 + I+HP V ++ L+P + D Q + E+Q + + L ++N Q+MCE+ + L+ A++ PLHS + +FE+LA+Q + P +R FL L P T D +T C SG +++ P L T+ +G + + + + +I+ T + R A PSFVE +M EG+GCLF+P+++ +S SV R FPP GG +FS W + + + HP+R L+L R L + + C ++S+ P+ + ++VST+E+ F + + S+ + C LL W HL + + M +H + S L+GQ+I + K+ YI + F SM + VY YI T + S+L WR GP + EE ++ + I +LGP Y GNFQ + D ++ VAEE+V F L+ + SI ++ I YNE+D +IA+++++ ++ + P+ ++ N AGHLSG+ R++GA+ +G G+R F +P +D +GG +LLG++++A D +YA VK++ S L N ++ L H+ GY++++FLL+KK LL+ RIF L++ + G+ + F+ I N +F ++C+ LW++ + L ++ H+ E Q + ++++ + L+ ++I L + ++ P ++TII ++ + DL R G F+V+TL +E +I ++ L + + + I +RN +++L ++++ ++E K EE+ LG DW LL +Q +H ST VLA++ L+ L+ P +FRDG+ W+ G D+V MDN + Q + C LPGF L L HH IP++Y ++ L + + D K++ Sbjct: 826 AAIMHPGVVCIMVRLLPRLYHEDHPQLSE--EIQCSLASHIQSLVKSEKNRQVMCEA-GLLGTLMASCHRALVTSGSPLHSRLIRIFEKLASQAIEPDVLRQFLGLGIPSSLSATTKILDSSHTHRGNPGC----------------SGSQTAQGLAEGPWPAAPDAGLHPGVTQAPQPLGESQDSTTALQTALSLIS-MTSPRNLQPQRAALAPSFVEFDMSVEGYGCLFIPTLSTVMGTSTEYSVSGGIGTGAT---------RPFPPPGGLTFSCWFLISRHGAATEGHPLRFLTLVRHLARTEQPFVCFSVSLC--PDDLSLVVSTEEKEFQPLDVMEPEDDSEPSAGCQLQVRCGQLLACGQWHHLAVVVTKE-MKRHCTVSTCLDGQVIGSAKMLYIQ-ALPGPFLSMDPSAFVDVYGYIATPRVWKQKSSLIWRLGPTYLFEEAISMETLEVINKLGPRYCGNFQAVHVQGEDLDSEATPFVAEERVSFGLHIASSSITSVADIRNAYNEVDSRLIAKEMNISSRDNAMPVFLLRNCAGHLSGSLRTIGAVAVGQLGVRVFHSSPAASSLDFIGGPAILLGLISLATDDHTMYAAVKVLHSVLTSN-AMCDFLMQHICGYQIMAFLLRKKASLLNHRIFQLILSVAGTVELGFRSSAIT----------------NTGVFQHILCNFELWMN------TADNLELSLFSHLLEILQSPREGPRNAEAAHQA----------------QLIPKLIFLFNEPSLIPSKISTIIG-----ILACQLRGHFSTQDLLRIGLFVVYTLKPSSVNERQICMDGALDPSLPAGS-QTSGKTIWLRNQLLEMLLSVISSPQLHLSSESK--EEMFLKLGPDWFLLLLQGHLHASTTVLALKLLLYFLASPSLRTRFRDGLCAGSWVERSTEGVDIV---------MDNLKSQSPLPEQ---SPCLLPGFRVLNDFLAHHVHIPEVYLIVSTFFLQTPLTELMDGPKDS 1740 HSP 3 Score: 139.043 bits (349), Expect = 7.400e-31 Identity = 158/677 (23.34%), Postives = 312/677 (46.09%), Query Frame = 2 Query: 302 VSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPP---WDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284 VS + ++++K + E+A LA Q L + + G++LL + +L+ + + + + LP+ ++CLY+FF P ++ ++ + D V + F Q+L IC E L+ +L+ L +A+ C +S W++ VL+ I+ + S IQ++ + L+N+++ L + E+ + + +++S V+ L +F NS+GY ++ + L++ + +E + + L+ L+ LTTCG EL+ + I YP +EGF+ + +++N AF VLQ+VF A LC+++L I+T++ + N+F+LE F E + K VQE L++ +V L+YVP + + + ++K T + +++ + + + +F ++ +D G+L + + QL A ++K + + V + + EL +++ + L+ +N + + G +V F+K + +L ++ L+ + +EE MS +G + S ++Q L + + + + R FR F + L LEG + +PP W + ++ LE V L ++ AL +P N +F N + L E + LGCFG+ Sbjct: 99 VSDQLAQQLQKALVGKPAEQARLAAGQLLW-----WKGDVDQDGYLLLKSVYVLTGTDSETLGRVAESGLPALLLQCLYLFFVFP---LDKDELLESD-----------------LQVQKM------FVQMLLNICSDSQGLEGLLSGSELQSLL--IATTCLREHSCCFWKEPTFCVLRAIS-KAQNLSIIQYLQATDCVRLSLQNLSRLTDTLPAPEVSEAVSLILGFVKDSYPVSSALFLEFENSEGYPLLLKVLLRYDGLTQSEVD-PHLEELLGLVVWLTTCGRSELK----VFDSITYPQLEGFKFHHEAS-GVTVKNLQAFQVLQNVFHKASDSVLCIQVLSVIRTMWAWNARNFFLLEWTLQPISQFVEIMPLKPAPVQEHFFQLLEALVFELHYVPHEILRKVQHLIKESPGPSCTLMALQSILSIAGGDPLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKVSTPGVQDPERELTCVMLRIVVTLLKGSVRNAVVLKDHG-------MVPFIKIFLDDECYREASLSILEQLS-AINAEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILVTPKGRAAFRVSSGFNGLLSLLSDLEGS---LQEPPLQAWGAVSPRQTLELVLYTLCAVSAALHWDPVNGYFFRRNGLFEKLAEDLCLLGCFGA 723 HSP 4 Score: 67.0106 bits (162), Expect = 4.474e-9 Identity = 101/460 (21.96%), Postives = 198/460 (43.04%), Query Frame = 2 Query: 5900 MCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSL----PARKLIMDFFKMIIVDYFSLPKNSYQHV-IDIILECDIENTTQEHMKQFQTVFMNSLTEHFM------AVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLI-----SQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLK-LNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQIC-------LKTWNSYIESENIGTAS----SHWGRISL 7171 +C+E A +LL M++ ++Q +E+ W + +P ++L+F + L H +FL L A +P + N SPE+ ++ T+E L + PAR+ + +F ++++ + + Q + ++++LE ++ T + + FQ+ + S E F A G+ + A NI F ++V+K++ + DP I+ ++ I + +R +LY S N++IL+ LS+ ++ + + L L ++ +F NS+ F++CL+H L+ L G+ ST++ +++K+ + L + I+ ++LWQ++ ++Q LE+AFKI LS IE++ LK W Y+ SE AS +H +++L Sbjct: 1762 LCTEGALLLLEMLKATMSQPL--AGSEDGAWAQTFPASVLQF-LSLVHRTYPQDPAWRAPEFLQTLAIAAFPLGAQKGVGAESTRNTSSPEAAAEGDS----------------TVEGLQAPTKAHPARRKLREFTQLLLRELLLGASSPKQWLPLEVLLEASPDHATSQQKRDFQSEVLLSAMELFHMTSGGDAAMFRDGKEPQPSAEAAAAPSLANISCFTQKLVEKLYSGMFSADPRHILLFILEHIMVVIETASSQRDTVLSTLYSSLNKVILYCLSK------PQQSLSECLGLLSILGFLQEHWDVVFATYNSNISFLLCLMHCLLLLNERSYPEGFGLEPKPRMSTYHQVFLSPNEDVKEKREDLPSLSDVQHNIQKTVQTLWQQLVAQRQQTLEDAFKIDLSVKPGEREVKIEEVTPLWEETMLKAWQHYLASEKKSLASRSNVAHHSKVTL 2196
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q55DM1|LVSA_DICDI (BEACH domain-containing protein lvsA OS=Dictyostelium discoideum OX=44689 GN=lvsA PE=4 SV=2) HSP 1 Score: 570.466 bits (1469), Expect = 1.066e-161 Identity = 308/775 (39.74%), Postives = 444/775 (57.29%), Query Frame = 2 Query: 8315 MFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAF-PKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSI------------------FSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDP-----SGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPY-GDIMCVLCLNE-RILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVP 10561 M+ C + G+D EG+L+F Y YI DG+ K +I+ + ++ +P + K+++ +IR+V KRRYLL+ +A+E+F DGRN L+ + + ++++Y + SS ++I G Q I G T F++ + +T +W++G+ISNFQYLM+LNTLAGRSYNDL QYPVFPW+L+DYESE LD+ P +R L KPMGA E+R +F +R+ WDD + P +HYGTHYSSA IV +YL+R+EPFTQHFLKLQGG +D DR+F SI + W S+SQ + + ELIPEF+YL FL N NKF+ G KQ G + DI+LPPWAKG +EFI+ HR+ALE DYVS HL+EWIDLIFGY+Q G AA +++NVF++L YEG V+I +I DP++++A I INNFGQ PKQLF KPHP + A L + N +K++ VGQI L + VG NK L+PP +++Y+ WG DGS+R Y++ IKV E D + G + C+ + RI ++GG +++ V+N+ SL L GH ++TC++ + Y+++VSGS DRTCI+WDL R+CY+R L H P++ I I + TG + C+GT + +++++GE L + T+ + QI S +W NV++TG DG V++W LE +P Sbjct: 2815 MYNCGSVDGMDKIEGILIFCPVYMYIFDGY--YKDENTGDISEVEEKINSEWLPEGTVLPMKKKIIHYFLKWAYEDIRDVLKRRYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLVNNVSS-----HNTIGGDAQG--ITGGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISNFQYLMHLNTLAGRSYNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQKFRERFENWDDQEPNEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPDRLFSSITEAWASSSQGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPWAKGSPQEFIKLHRKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGAVNIDAISDPVEKAATIAQINNFGQTPKQLFDKPHPKRN---------------ATLMGLPFYAKALTGNF---------IKDIGEPVGQI---RLINDRATCVGF----------NKVLLPPNHSKYMLWGLPDGSIR---YNTGDKIKVLE--DHHDGPLTCLTATEDGRICVSGGSDSLICVYNLK----------------------RFSLAKRLSGHTGSITCVSASRPYSIIVSGSDDRTCIIWDLNRLCYVRSLDAHEGPISCIGIHDTTGEIVVCSGTTISVYTVNGELLINYKTSQIANDQITCCIWSKGPEWLGENVLLTGHRDGKVKVWGLETRLLP 3516 HSP 2 Score: 87.8113 bits (216), Expect = 2.736e-15 Identity = 114/535 (21.31%), Postives = 238/535 (44.49%), Query Frame = 2 Query: 113 TDSSLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFH--KIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQ------NSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYP---ATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIE-IVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPM---------NKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISV 1651 + ++ +LK+L+ ++ +K ++ ++LL I L+ KI +P +++ F+F +S +V++I + + + Q ++ + + ++ + + G+ LL + ILS E M AS+PS V+CL FF +P + +M T + I+ + ++++ +CF + EEL + + L LF +++ CP + R + L TI +I K++I+ +K++T + + E V + + +L ESS + +LLD+F+ + GY + L + S++ + L+ I L GY N+S+ P+E +P N+N +N AF VL+ FL + + ++IL+ I ++Y + N+ +L+ +T F ++ S ++ ++ ++ +V LN VP +E+S+ S+++ T ++ + L+ +K + ++ G+L+I V Sbjct: 143 SQATAQKLKLLWQEFLSSKSDKDKVMRLNKLLPYFIGLYEDKKIDTKSPMVDIFGNNSKSFSFA--ISRRLVKDINEIMKQANSPQQPPQPPQLIKETIAKEIYKFFSTTSGQVSGFELLYSIEILSESNTSCAEAMAEASIPSMLVRCLQYFFLVP-----------YTTMMETT----------------KGIIEE---KLIRTLCFLSKQKSAIEELQKTDTLSTLFALMSNECPPSHRPLRAKIGSF--GLELTDLYPPTITYINSKRVIANIIKDLTNYYMFTPESYVTLCRIIIKILSESSKKSTILLDEFQRNDGYT---FLVDSLFRLESSKDKPALFEQLLDSICSLVYIGY------GNVSL----PVENSSVPYQTSINNIKEISNQNYISKNGNAFKVLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQEYESLSNGLKYHVMKIVCFVVTVLNCVPFQELSTFSLLVGENPSFYTLEMINQLITTLVNFEFRYKHIFRETGLLDILV 630 HSP 3 Score: 74.7146 bits (182), Expect = 2.141e-11 Identity = 37/88 (42.05%), Postives = 52/88 (59.09%), Query Frame = 2 Query: 7502 KWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELY 7765 +W+++ +++ RER +WGP LDKW LDS EGP RMRKKM N FY++YPY P P + +N+ + + SAD E Y Sbjct: 2486 QWENMRAQITRERAVWGPSEPHPLDKWKLDSTEGPYRMRKKMEKNYNFYKNYPYVP----PSFDEQNNSLL------PIPCSADSETY 2563
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: A0A5G3JJ76 (WD repeat and FYVE domain containing 3 OS=Xenopus tropicalis OX=8364 GN=wdfy3 PE=4 SV=1) HSP 1 Score: 2425.59 bits (6285), Expect = 0.000e+0 Identity = 1469/3872 (37.94%), Postives = 2167/3872 (55.97%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLE-SAEFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQP-GFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F ++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL V+ +L+ ++CM T S+PST +KCLY+FFDLP+ P+I + + P RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ NE+ +D+++ + LI LTT G EL+P L+ + + GF +P P K S+RN AF+VLQ+ FL A+T +L IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + K ++ I H+ IFK+V K++G+LE+ VN LH YA LK EQ ++ EQ +L L++++ LT+L+ + N +FR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L IVL+ESHR R VFRKV FV LV +E S + W+ + + ++ E + + LT A++ EP+N +F + Y L +AIR LGCF S + N S+NQ F+ L D + + V +L CS+ + ++Y A + FD H + + S P + MKL S+++ ++I+HP A++S++ L+ ++ D +Q H ++LQ+ I L L +RN Q+MCE+ + LL+ A+ NE+HPLH +FERLA+Q + P +R+FLRL DPL C S+ Y+P + + G G D FC R N G + LTRVK L+ +TT D + P+FVE + EGFGCLFLPS+AP + + + + G G R+FPP G ++STW C++ SS HP+RLL+L R S + CLNI ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL+ T KL+Y+ S + ++++VYAYIGT P ++S L WR GP HF+EE LTA+ V I LGPNY+G+FQ P D ++ GSL V EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HN+AGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ L KKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R D L+ +++ + +++ P I+ LS L++ S +DL RFGQF+ TL E + + NN+ LE +F + LI +RN ++LK+L S T + EEL+K LGFDW ++FM+ +H +TV AMR LV LLS P +L+F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQSLLP H +P +YF+L+ L L + +P+NL+ + P IS +N+S QF+ +S+ F+FG +SG+ +++ +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + + + +FL L +++P + D + S ++ F+ +S + +++E C M T L + PA+K + DF ++++++ L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GG+Y + NN++YF RVVDK+WQ + D +++ + +LISQ ++R ++ E++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G N G+ +TW+ P I D + + ++ + L L R +W E+ +KKQ+LE+ FK+ + ++ ++ P IE+ L+ W +++ E T+ +P S + S +++G +S KL RN L+ +++S +E W+ HI+VV++L+D + +++ + Y+ +W E EL RERGLWGP +GS LDKWML+ EGPCRMRKK++ N+ FY HYPY P + E+ + +++ A S D + D Y +L P N + TVEE+ + ++ +PE +T + ++G P+K D +D E++E M D + +E +S E ++ +DS+ ++ ++ EKI M+RCAR+QGLD EGLLLFG+ +FY++DGFT+ TREI +I +P+++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ IN + M+ L +++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STV+ VW + K A +L+L+ L GH + VTCL + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT GRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP + + AD E P + G E+ S+ E+ Q+ + S+ N S + + ++ + D SD+ S++++ D +DG V + N SKVQ ++S SQ +R + KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ + RN Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENEL-----------------PL-AERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDR----------------HVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPDDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENLQVSAPV-----------ISSRSNRSCQFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIP-------DAEHETNTMKPARYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGQEAQDDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3479
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: A0A5G3HUJ1 (WD repeat and FYVE domain containing 3 OS=Xenopus tropicalis OX=8364 GN=wdfy3 PE=4 SV=1) HSP 1 Score: 2419.81 bits (6270), Expect = 0.000e+0 Identity = 1477/3892 (37.95%), Postives = 2175/3892 (55.88%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFD-----------NXXXXXXXXXXXXXXXXHYLKTIVSDSSF-IP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRP--YHRS---PCDNNENHCQ-VYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQP-GFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F ++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL V+ +L+ ++CM T S+PST +KCLY+FFDLP+ P+I + + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ NE+ +D+++ + LI LTT G EL+P L+ + + GF +P P K S+RN AF+VLQ+ FL A+T +L IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + K ++ I H+ IFK+V K++G+LE+ VN LH YA LK EQ ++ EQ +L L++++ LT+L+ + N +FR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L IVL+ESHR R VFRKV FV LV +E S + W+ + + ++ E + + LT A++ EP+N +F + Y L +AIR LGCF S + N S+NQ F+ L D + + V +L CS+ + ++Y A + FD N L K ++ VS SS P + MKL S+++ ++I+HP A++S++ L+ ++ D +Q H ++LQ+ I L L +RN Q+MCE+ + LL+ A+ NE+HPLH +FERLA+Q + P +R+FLRL DPL C S+ Y+P + + G G D FC R N G + LTRVK L+ +TT D + P+FVE + EGFGCLFLPS+AP + + + + G G R+FPP G ++STW C++ SS HP+RLL+L R S + CLNI ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL+ T KL+Y+ S + ++++VYAYIGT P ++S L WR GP HF+EE LTA+ V I LGPNY+G+FQ P D ++ GSL V EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HN+AGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ L KKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R D L+ +++ + +++ P I+ LS L++ S +DL RFGQF+ TL E + + NN+ LE +F + LI +RN ++LK+L S T + EEL+K LGFDW ++FM+ +H +TV AMR LV LLS P +L+F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQSLLP H +P +YF+L+ L L + +P+NL+ + P IS +N+S QF+ +S+ F+FG +SG+ +++ +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + + + +FL L +++P + D + S ++ F+ +S + +++E C M T L + PA+K + DF ++++++ L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GG+Y + NN++YF RVVDK+WQ + D +++ + +LISQ ++R ++ E++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G N G+ +TW+ P I D + + ++ + L L R +W E+ +KKQ+LE+ FK+ + ++ ++ P IE+ L+ W +++ E T+ +P S + S +++G +S KL RN L+ +++S +E W+ HI+VV++L+D + +++ + Y+ +W E EL RERGLWGP +GS LDKWML+ EGPCRMRKK++ N+ FY HYPY P H + C N C+ + Q +++ A S D + D Y +L P N + TVEE+ + ++ +PE +T + ++G P+K D +D E++E M D + +E +S E ++ +DS+ ++ ++ EKI M+RCAR+QGLD EGLLLFG+ +FY++DGFT+ TREI +I +P+++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ IN + M+ L +++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STV+ VW + K A +L+L+ L GH + VTCL + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT GRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP + + AD E P + G E+ S+ E+ Q+ + S+ N S + + ++ + D SD+ S++++ D +DG V + N SKVQ ++S SQ +R + KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ + RN Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENELP------------------LAERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDSRAEQIPPCLTNETSLPSPWGTPAVSRKRHVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPGADDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENLQVSAPV-----------ISSRSNRSCQFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIPDAEHETNTMVCFNKICSCKCIGQKSRYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGQEAQDDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3522
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: A0A5G3JJY3 (WD repeat and FYVE domain containing 3 OS=Xenopus tropicalis OX=8364 GN=wdfy3 PE=4 SV=1) HSP 1 Score: 2410.18 bits (6245), Expect = 0.000e+0 Identity = 1466/3884 (37.74%), Postives = 2159/3884 (55.59%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFD-----------NXXXXXXXXXXXXXXXXHYLKTIVSDSSF-IP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F ++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL V+ +L+ ++CM T S+PST +KCLY+FFDLP+ P+I + + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ NE+ +D+++ + LI LTT G EL+P L+ + + GF +P P K S+RN AF+VLQ+ FL A+T +L IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + K ++ I H+ IFK+V K++G+LE+ VN LH YA LK EQ ++ EQ +L L++++ LT+L+ + N +FR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L IVL+ESHR R VFRKV FV LV +E S + W+ + + ++ E + + LT A++ EP+N +F + Y L +AIR LGCF S + N S+NQ F+ L D + + V +L CS+ + ++Y A + FD N L K ++ VS SS P + MKL S+++ ++I+HP A++S++ L+ ++ D +Q H ++LQ+ I L L +RN Q+MCE+ + LL+ A+ NE+HPLH +FERLA+Q + P +R+FLRL DPL C S+ Y+P + + G G D FC R N G + LTRVK L+ +TT D + P+FVE + EGFGCLFLPS+AP + + + + G G R+FPP G ++STW C++ SS HP+RLL+L R S + CLNI ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL+ T KL+Y+ S + ++++VYAYIGT P ++S L WR GP HF+EE LTA+ V I LGPNY+G+FQ P D ++ GSL V EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HN+AGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ L KKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R D L+ +++ + +++ P I+ LS L++ S +DL RFGQF+ TL E + + NN+ LE +F + LI +RN ++LK+L S T + EEL+K LGFDW ++FM+ +H +TV AMR LV LLS P +L+F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQSLLP H +P +YF+L+ L L + +P+NL QF+ +S+ F+FG +SG+ +++ +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + + + +FL L +++P + D + S ++ F+ +S + +++E C M T L + PA+K + DF ++++++ L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GG+Y + NN++YF RVVDK+WQ + D +++ + +LISQ ++R ++ E++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G N G+ +TW+ P I D + + ++ + L L R +W E+ +KKQ+LE+ FK+ + ++ ++ P IE+ L+ W +++ E T+ +P S + S +++G +S KL RN L+ +++S +E W+ HI+VV++L+D + +++ + Y+ +W E EL RERGLWGP +GS LDKWML+ EGPCRMRKK++ N+ FY HYPY P + E+ + +++ A S D + D Y +L P N + TVEE+ + ++ +PE +T + ++G P+K D +D E++E M D + +E +S E ++ +DS+ ++ ++ EKI M+RCAR+QGLD EGLLLFG+ +FY++DGFT+ TREI +I +P+++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ IN + M+ L +++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STV+ VW + K A +L+L+ L GH + VTCL + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT GRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP + + AD E P + S+ E+ Q+ + S+ N S + + ++ + D SD+ S++++ D +DG V + N SKVQ ++S SQ +R + KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ + RN Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENELP------------------LAERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDSRAEQIPPCLTNETSLPSPWGTPAVSRKRHVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPGADDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENL-------------------------QFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIP-------DAEHETNTMKPARYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGLDCYDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3493
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: A0A5F8H7K0 (WD repeat and FYVE domain containing 3 OS=Monodelphis domestica OX=13616 GN=WDFY3 PE=4 SV=1) HSP 1 Score: 2377.44 bits (6160), Expect = 0.000e+0 Identity = 1448/3881 (37.31%), Postives = 2157/3881 (55.58%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAG-ISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXX------------XXXXXXXXXXXXHYLKTIVSDSSF----IPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD----------FCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYENPIG-----SLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLL---MDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQID-PMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-----PQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQ 11383 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE+ Q + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP +N WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ E+ +D+++ L+ LI LTT G EL+P ++ + + GF +P P K S+RN AF VLQ+ FL A+T++L IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + + + K ++ H+ IFK+V +++G+LE+ VN LH YA LK Q DS NN +Q +L LL+++ LT+L+ + N +FR+ GG+ C ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E S K W+ + + ++ E + + LT A++ EP+N +F + Y L +A+R LGCF SD+ I N N+Q + L D + +SVS L CS+ + ++Y A + F++ S +H ++ + S + + + + P PS + + ++++HP A+++++ L+ ++ +Q H ++LQ+ + L L +RN Q+MCE+ + LL A+ +E+H LH +FERLA+Q + P +R+FLRLA+PL C N + S+ Y+P G G D + S ++ G + LTRVK L+ +TT D A P+FVE + EGFGCLFLPS+AP + + ++ ++ G G R FPP G S+S+W C++ FSS HP+RLL+L R S + CL I ++++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +++GQL+ T KL+YI S + ++++VYAYIGT P ++++L WR GP HF+EE L S V+ I LGPNY+G+FQ P D ++ G SLV EEKV F LYA ++S T+ +I K+YN+LD IA+QL + E ++P++++HN+AGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L R + L P I+ LS L++ + N +DL RFGQF+ TL E + + NN+ L++ ++ L+ + + L + + + E + E+L++ LGFDW+L+F + +H +TV AMR LV LLS ++KF++G+ GWL TD VL + G +L + + +A+REIN D+CH PGF LQS LP H +P +YF+L+AL L + +P+NL+ + P IS NQ QF+ +S+ F+FG ++GP+ ++ + C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + S+ M +FL L ++P + D + S ++ F+ ++ + +++E C N+ + +T + PA+K + DF +++I+D L P + +ID++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GGSY + NN++YF RVVDK+WQ + + ++I ++ +LI+Q ++R ++ +++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G ++ G+ +TW+ +PDS + ++ + Q+ +N +W E+ +KKQ LEE FK+ + ++ P IE+ LK W +++ E + R +P + + S +++G +S KL RN L+ +++S++E W+ HI+VV++L+D + +++ + Y+ +W +E EL RERGLWGP +GS LDKWML+ EGPCRMRKKM+ N+ FY HYPY P E V + +++ A S D + Y Y +L+ S NP V++ I S+E E + + E G DT +KG + + ++ P D DEE N++ + +DS SR E E+ D++ ++ ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P RR S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPW+LADY+S+ +DL +P TFR L KPMGAQ++ RL Q++KRYR+W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LG+++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAV+AVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ ++ N + P P ++++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C + +++ITGG STVV VW M + K A L+L+ L GH + VTC + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT TGRS+QI+ MS M +WD NV++TG +DGVVR W +E++QVP + + + E P+A Q G + S + D +E S+ ++ + A S A ++ + D SD+ S++++ D +DG +N E +Q L P + L+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ I++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEVVGGAQNELP------------------LAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAES-KDALKDLVNLITSLTTYGVSELKPA-GITTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNYLPQIILDAITNIYIADNANYFILESQHTLSQFAEKISKLP-EVQTKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYQCSIIATKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAAFLKDPQALNEQGDSKNNSSVEDQKQLALLVMETLTILLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMIIQQLVLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRTRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISPLNVFPSNTQP-------FQRLLEDDLTSVDSVS---------------PTLRHCSK----------LFIYLYKVATDSFESHAEQIPPCLTNESSLPSPWGTPAVSRKRHAYHSVSTPSGYSSKNVADLKQQPAAPS-LQSSDAVVIHPGAMLAMLDLLSSV-GSPSQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPVVLREFLRLANPLNCGAWDKNLLKQYRIHKPSSLSYEPEMRGSMVTSIEGLGSDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSAVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNAATAGLTDGTVISGIGSGE--RFFPPPSGLSYSSWFCIEHFSSSPNHHPVRLLTLVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGDLIVEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYIHSTPGGSGSANPPVVSTVYAYIGTPPAQRQLASLVWRLGPTHFLEEVLPISSVNIIYELGPNYVGSFQAVHVPCKDSKSESGIQSPVSLVPEEKVSFGLYALSVSSLTVAKIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTVGAALIGYLGVRTFIPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIVAISNVLSFLLQ---GFPNS-NDLLRFGQFIASTLPTFAVCEKFVVMEINNEEKLDTGTEEDFGVLVSANLILLRNRLLDILLKLIYSSKEKTSINIQACEDLVRTLGFDWLLMFTEEHLHSTTVTAAMRILVVLLSNQSVLIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSAIREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVTELPENLQVSVPV-----------ISSRCNQGCQFDLDSIWTFIFGVPA---------------SSGPVVSSIHNV-------------------CTEAAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPEFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAVDTGMNRSQSEYC-----NVGSKTYLT-----NHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSHVDGFGLEAEARMTTWHIMIPSDIDPDSSCSQDVSEGR-QLLIKAVNR--------VWTELIHSKKQTLEELFKVTLPVNDRGLVDITIARPLIEEAALKCWQNHLAHEKKCIS-----RGEALVPSTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSMQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYMP-------ETEQETNVLKPARYRRAVSYDSKEY--------------YMRLA-------SGNPAFVQDAIIESSEG-ESTQQEPE---HGE-------DTIAKVKG--LVKPPLKRSRSAP----DGGDEE--NQEQLQDQIAEDS---------SREE--------EEKTDNATLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLRRSCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWVLADYDSQEVDLANPKTFRNLAKPMGAQTDERLTQYKKRYRDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGNVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVDAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNSGLSVPPGPT-----SDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAICPSPKLVITGGTSTVVCVWEMGTSKEK---------------AKTLTLKQALLGHTDTVTCSTASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPVVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPIEDLEMQEDCPEAQIGQEG-QDEESSDSEAEESSIIQDPKETPSQPGSVSHRPRAA----SCRAAAVWSADSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQPRVHLQGPLNHPHPYPVDVRHYNSLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEITALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHER 3499
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: M7BQI5 (WD repeat and FYVE domain-containing protein 3 OS=Chelonia mydas OX=8469 GN=UY3_12513 PE=4 SV=1) HSP 1 Score: 2369.35 bits (6139), Expect = 0.000e+0 Identity = 1455/3894 (37.37%), Postives = 2160/3894 (55.47%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQN-WSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPN---PMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYI----------SQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYEN------PIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNE-NQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRP-----------YHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNE------DPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDE----------ETFNKDNMFSDTVDDSDFPLDTEKTSRSE-SKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQ--AVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTL--LKSLSQP---QMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQS 11386 MN V+RI+ + + +D L L+ LF + + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE+ Q + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP N WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SSDV+Q LLDDFR QGY + + L++LE+ E+ +D+++ L+ LI LTT G EL+P ++ + + GF +P P K S+RN AF+VLQ+ FL A+T++L IL+AI IY D ANYFILE Q+T F+EK+ K VQ + +++ +V +LNY+P KE+ S+S+++K+ + + +K ++ H+ IFK+V +++G+LE+ VN LH YA LK A DS NN +Q +L LL+++ LT+L+ + N +FR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E K W+ + + ++ E + + LT A++ EP+N +F + Y L +A+R LGC+ +S ++ N + SN + L D +SV+ L CS+ + ++Y A + FD H ++ + + P +KL + + + ++I+HP A+++++ L+ ++ Q H ++LQ+ + L L +RN Q+MCE+ + LL A+ +E+H LH +FERLA+Q + P +R+FLRLA+PL C + + S+ Y+P + G G D + S ++ G + LTRVK L+ +TT D + P+F+E + EGFGCLFLPS+AP + + + + G G R FPP G S+STW C++ FS+ HP+RL ++ R S + CL I I+++ + ++VSTKEE+ N E S A F C L+ E W HLVL + GM+K+S+ + +L+G L++T KL+Y+ + S + ++++VYAY GT P +IS+L WR GP HF+EE L S VS I LGPNY+G+FQ P D ++ P+ SLV EEKV F LYA ++S T+ RI K+YN+LD IA+QL + E ++P++++HN+AGHL+G R++GA LIGY G+R F P P+ + +GG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L R + L P I+ LS L++ S +DL RFGQ + TL E + + NN+ LE+ ++ L + + L + + + E + +EEL++ LGFDWI+LFM+ +H +TV AMR LV LLS ++KF++G+ GWL TD VL + G +L N +REIN D+CH PGF LQS LP H +P +YF+L+AL L + +P+NL+ + P + S NQ QF+ +S+ F+FG G +++ I+ +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + S+ M +FL L ++P + D + S ++ F+ ++ + +++E C N+ + +T + PA+K + DF +++I+D L P + ++D++LE E +T+ K+FQT ++S+ +H +A D+L G++ LP+ GGSY + NN++YF RVVDK+WQ + + +++ ++ +LISQ ++R ++ +++Y NR IL++ SR K + + + L T + I P N D EF+ CL H LI L G + G+ +TW+ P I D + + + ++ + L L R +W E+ +KKQ+LEE FK+ + +++ P IE+ LK W +++ E + R +P + + S +++G +S KL RN L+ +++S +E W+ HI+VV++L+D + +++ + Y+ +W +E EL RERGLWGP +GS LDK ML+ EGPCRMRKKM+ N+ FY YPY P + P + ++ + +++ A S D + YY +L+ S NP ++ I S+E +PE +T + ++G S P GD + ++ QD + ID+E++ E K F +T D LD S+ S++ LN + S S HM G +I M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P +R S F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V SLT ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+S LDLT+P TFR L KPMGAQ+E RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD++LPPWAKGD REFIR HREALECD+VSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ S IN + M+ + + +++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK LIPP + + AWG++D S R+G Y+SDK + VYE +G I+C +C N +++ITGG STVV VW M + K A L+L+ L GH + VTC + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G + SVNT TGRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP + + + E Q +Q G E+ + + + E D + I Q +K E++SQ + + + S S+ GS++ S+ +DG V N S+ Q+ + ++ P ++R + KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ I++L IS+DH I VGD RGRVF WSV +PGRS ADHW++DE + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++ PVRVC C+Y++ ++ Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEVVGGAQNELP------------------LAERRTLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPCNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAES-KDALKDLVNLITSLTTYGVNELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFSVLQNAFLKAKTNYLAQIILDAITNIYIADNANYFILESQHTLSQFAEKISKLP-EVQTKYFEMLEFVVFSLNYIPCKELISVSILLKSSTSYQCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNDQGDSRNNSSFEDQKQLALLVMETLTVLLQGSNTNAGIFREFGGARCVHNIVKYPQCRQHALMIIQQLVLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRTRTVFRKVGGFVYVTSLLVAMERSLCSPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRLLGCYS---------DSRKISPLNVFPSNTQPFQRLLEDDLISMDSVA---------------PTLRHCSK----------LFIYLYKVATDSFDR----------------HAYHSVSTPPVYPPKNIADLKLHTGATLLQSSDAVIIHPGAMLAMLDLLASV-GSTAQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLANPLNCGAWDKKLLKLYRVHKPSSLSYEPEMRSSMVTSMEGLGSDSVFSLHEDNHYRISRSLLKPAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFIEFDTSLEGFGCLFLPSLAPHNAPTNNAVTTGLVDGAVVSGIGTGE--RFFPPPSGLSYSTWFCIEHFSTPPNNHPVRLFTVVRRANSSEQHYVCLAI-ILSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGDLIVEGQWHHLVLVMSK-GMLKNSTAALYLDGLLVNTVKLHYVHSSPGGSGSTNPPVVSTVYAYTGTPPAQRQISSLVWRLGPTHFVEEVLPLSSVSTIYELGPNYVGSFQAVYIPCKDSKSEGVSPSPV-SLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAVSSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQGFPS----SNDLLRFGQVISSTLPTFAVCEKFVVMEVNNEEKLETGTEEDFGGLASANLILLRNRLLDILLKLIYTSKEKTSVNLQASEELVRTLGFDWIMLFMEEHLHSTTVTAAMRILVVLLSNQPILIKFKEGLSGGGWLDETDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVTELPENLQVSAPVS-----------SSRCNQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIN----------------NVCTEAAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLTSMWMSPEFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFRAFAADTGMNRSQSEYC-----NVGSKTYLT-----NHPAKKFVFDFMRVLIIDNLCLTPASKQTPLVDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLVDFIIQLISQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFICCLAHCLINLHMGSGVDGFGLEAEARMTTWHIMIPSDIEPDGVYNQDISEGRQLLLKAINR-----VWTELIHSKKQVLEEVFKVTLPVNDRGHVDIVVARPFIEEASLKCWQNHLAHEKKCIS-----RGESLVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSTQEISQWMFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWSQIEYELLRERGLWGPPIGSHLDKCMLEMTEGPCRMRKKMVRNDMFYIQYPYMPETEQETNLLSDFSSKPPETPDDTIPQKKPTRYRRAISYDSKEYY--------------MRLA-------SGNPAVFQDTIEESSEGEATQQEPEHG-EDTIARVKGLVKPPLKRSRSAPDGGDEENQEQLQD-QIAEGSSIDEEEKTDNTTLLRLLEEGEKVQYFRNT--DQLLYLDFYFVPFSDFSRVMVLNVDSSSRSV-------------------------------HM-GVPLQIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNLHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSAELDLTNPKTFRNLAKPMGAQTEERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDFVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---SRINGDVVGMS-VPPGSTNDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAVIVYECLSEWGQILCAICPNPKLVITGGISTVVCVWEMGTSKEK---------------AKTLTLKQALLGHTDTVTCSTASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPVVSVNTFTGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEILEMQEDCPEAQIGQEA-----QDEDSSDSEADDQCISQDTKPQESQSQPNSTSHRPVPSSSRAAAWSA--------DSGSDDSRRWSDQLSLDEKDGFIFV---NYSEGQTKVHPHAQVNHPNHVEVR-HYSKLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEITALGISKDHSRILVGDGRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERG 3535
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:103029491]) HSP 1 Score: 987.638 bits (2552), Expect = 0.000e+0 Identity = 458/769 (59.56%), Postives = 586/769 (76.20%), Query Frame = 2 Query: 8255 QWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVP 10561 Q + + ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDGFT+ TREI +I +P ++HEPI+P + +R S F++ +I+EVHKRRYLLQP+AVEVF GDGRN+LLAF K ++NK+Y +F+ V SL ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY++E LDL +P TFR L KPMGAQ+++RL Q++KR+++W+DP+GETP YHYGTHYSSAMIVA YL+RMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG+KQNG LGD++LPPWAKGD REFIR HR+ALECDYVSAHL+EWIDLIFG+KQ G AVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+ S +N +I P P + S+ A+++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK L+PP + + AWG++D S R+ NY+SDK + VYE +G I+C +C N +++ITGG ST + VW MS K A L+L+ L GH +AVTCL +++Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + S AGTY+H+WSI+G +AS NT TGRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP Sbjct: 2492 QKTDNTTLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTVTREIRDIETLPANLHEPIIPRGARQSQSQLKRSCS-IFAYEDIKEVHKRRYLLQPMAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLA-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDAEELDLNNPKTFRNLSKPMGAQTDDRLIQYKKRFKDWEDPNGETPAYHYGTHYSSAMIVASYLLRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGSKQNGTRLGDVILPPWAKGDPREFIRVHRQALECDYVSAHLHEWIDLIFGFKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---SKLNGEI-PGMPASVSSTADKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLVPPAWNKTFAWGYADLSCRLANYESDKAVIVYECLSEWGQILCAICPNPKLVITGGTSTAICVWEMSTAKEK---------------AKTLTLKQALLGHTDAVTCLTASSAYHIIVSGSRDRTCIVWDLNKLSFVTQLRGHRAPVSALCINELTGDIVSSAGTYIHVWSINGNPIASANTFTGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVP 3225 HSP 2 Score: 769.615 bits (1986), Expect = 0.000e+0 Identity = 546/1744 (31.31%), Postives = 880/1744 (50.46%), Query Frame = 2 Query: 2603 LKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQ-----------MQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEV---FGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYEN---------PIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIE-----IRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKC--GNVINNIRNTEMITLES---LNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRP 7669 +K I ++ NP + P P +++HP AV++++ L+ ++ D Q H ++LQ+ + L L +RN QI+CE+ + LL AM +E+HPLH +FERLA+Q + P +R+FLRL +PL C + S+ Y+ G G D +++ ++ G + LTRVK L+ +TT D A P+FVE + EGFGCLFLPS+AP + SS ++ VS G G R+FPP G S+S+W CV++FS+ +HP+RLL++ R S + CL I ++++ + ++VSTKEE+ + + E S A F C L+ E W HLVL + GM+K+S + +++GQL+ T KL+Y+ S + ++++VY+YIGT P ++S+L WR GP HF+EE L A+ V+ I LGPNY+G+FQ L ++ P+ +LV EEKV FSLYA ++S T+ +I K+YN+LD IA+QL + E ++P+++IHNAAGHL+G R++GA +IGY G+R F P P+ + VGG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ S + ++ K R ++ LL L L ++ + P T I+ LS L++ + N DL RFGQF+ TL E + + +N+ ++ + L+ +RN I+LK+L +S + EEL++ LGFDW+L+FM+ +H STV A+ LV LLS + +F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQ+LLP H +P++YF+L+AL L + +PD+L+ +S +QF+ +S+ +F+FG +A +G + N +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + + DFL L A++P + ++ + + E+ TE K + N +E + S L + PA+K + DF K++I+D L P + +ID++LE E +T+ K+FQ+ ++S+ EH +A D++ G++ +P+ GGSY + NN++YF RVVDK+WQ + + +++ ++ +LISQ ++R ++ +S+Y NR IL++LSR K + + + L T + + P N D +FV CL H I L G N+ G+ +TW+ I ++N D + + + + +W E+ +K+Q+LE+ FK+ + ++ + P +E+ K+W +++ E + R +P + + S +++G +S+ + S K + M++ N++S +E W+ HI+VV++L+ + +++ + Y+ +W +E EL RERGLWGP +GS LDK+ LD EGPCRMRKKM+ N+ FY HYPY P Sbjct: 823 VKAITDLKLYLGNPSQHPSDP--------VVIHPGAVLAMLDLLASVSSDA-QPEHALDLQLAVANILQVLVHSERNQQILCEA-GLHSRLLQRCSCAMGDEDHPLHPPLQRMFERLASQALQPMVLREFLRLGNPLNCGAWDKKLLKQYRVHKPSSLSYEAEARNSMTTSMEGFGPDSVFAVNEDNSQYRISRSLVRSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSAVTPAFVEFDSSLEGFGCLFLPSLAPHNASSNNANTSGVSDGAVVSGMGTGE--RLFPPPSGLSYSSWFCVERFSTAPHSHPVRLLTVVRRATASEQHYVCLAI-VLSAKDRSLVVSTKEELLQSYADDFSEESSFYEILPCCARFRCADLITEGQWHHLVLVMSK-GMLKNSMATLYIDGQLVSTVKLHYVHSAPGGSGAANPPVVSTVYSYIGTPPAQRQLSSLVWRLGPTHFLEEVLPATSVAAIYELGPNYVGSFQAVYLPCKDSKTEAVPPCPV-ALVPEEKVSFSLYALSVSALTVAKIRKVYNKLDSKAIAKQLAVSSHENATPVKLIHNAAGHLNGPARTIGAAVIGYLGVRAFVPKPVATNLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLACKEMERIKGYQLLAMLLKKKRLLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLLREFQLIPKLL-LTLRDQSLS-------QPTITAISNVLSLLLQ---GFPNS-YDLLRFGQFLSSTLPTFAVCEKFVVMEVSNEEKIDGGNDDDFGGLLSSNVILLRNRLLDILLKLLFSSKEKSIVNAQACEELVRTLGFDWLLMFMEEHIHSSTVTAALWILVVLLSNQSILGRFKEGLSGGGWLDHTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFPVLQTLLPKHTNVPELYFLLMALFLQQPVTELPDSLQ--------------VHVS-----TQFDLDSIWSFIFGVPAS--------------SATVVGSIHN--------------------VCTEAAFLLLAMLRSMLNLPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLAPMWHSPDFLCALAAAVFPFN---IRPYSEMVTDLDDEAGSPTEEFKAFVADTGMNRSQSEYCNVGSKTYLTNHPAKKYVFDFMKVLIMDNLCLTPASKQTPIIDLLLEASPERSTRTQQKEFQSYILDSVMEHLLAADVMLGEDGSMPITTGGSYQVLTNNVFYFTQRVVDKLWQGMFNKESKLVVEFIVQLISQAKRRSQGLSLDSIYHCLNRTILYQLSR------PHKTVPQQVALLDSLRVLTVNRNLVLGPGNHDQDFVACLAHCFINLHTGSNVEGFGLEAEARMTTWHV--MIPSENEADTPHSQDVSEGRQLLLKAVNRVWTELMHSKRQMLEDIFKVSLPVNDRGHVDIATARPGLEEPAAKSWQNHLAHEKKCIS-----RGETIVPATQSKLSRVSSGFGLSKLTGARRSKKESGMNK--------------------------------NNLSAQETFQWMFTHIAVVRDLVAMQYKEYQERQQNALKYVTDEWAGIEYELLRERGLWGPPIGSHLDKFQLDMTEGPCRMRKKMVRNDMFYIHYPYVP 2389 HSP 3 Score: 473.396 bits (1217), Expect = 4.067e-133 Identity = 278/758 (36.68%), Postives = 443/758 (58.44%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKT-----CNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLK--KEQDAGISDSVNN---EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCF 2278 MN V+RI+ + + +D L L+ LF++ + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL + +L+ ++CM T S+PST VKCLY+FFDLP+ PE+ Q + RR +L F Q+L ++C + + EEL +K+DL+LLF A+ SWCP HN WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ + L +EIV++F L L++SS+V+Q LLDDFR QGY + + +++LE+ +E+ +D+++ L+ L+ LTT G EL+P L+ + + GF +P P K ++RN AF+VLQ+ FL A++ L +LEAI IY D ANYFILE Q+T F+E++ + VQ + L++ +V LNYVP KE+ S+SV++K+ C++ T +LL +L H+ +F +V +++G+LE+ VN LH YA LK + DS NN +Q +L L+++ LT+L+ + N LFR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S S L LK +L +L VL+ESHR R VFRKV FV LV +E W+ + + ++ E + + LT A++ EP+N +F + Y L +A+R LGCF Sbjct: 1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFSELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSTMNEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEVNQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHMPEVPAATQTELP------------------LADRRALLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPHNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCIQNMQQSDDLSPLEIVEMFAGLSCFLKDSSNVSQALLDDFRMCQGYNFLTDLMLRLEQAKEDES-KDALKDLVNLVTSLTTYGVSELKPA-GLTTGAPFLLPGFVVPQPSGKGHTVRNIQAFSVLQNAFLKAKSGRLARMVLEAIANIYAADYANYFILEAQHTLSQFAERVARLP-EVQAKYFELLEFVVFGLNYVPCKELFSVSVLLKSSTSYSCSITATRTLL-----KLSRHHPVFSDVFREVGLLEVLVNLLHKYAALLKDPTQTHGEHGDSKNNVADDQKQLAWLVMETLTVLLQGSNTNAGLFREFGGARCVHNIVKYRQCREHALMIIQQLVLSPSGDDDMGTLLGLMHSAPSTELQLKTDILRALLAVLRESHRTRTVFRKVGGFVYVTSLLVAMERSLGSQPAGSWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFRSEIQYEKLADAVRLLGCF 724
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1]) HSP 1 Score: 415.231 bits (1066), Expect = 2.400e-115 Identity = 267/798 (33.46%), Postives = 404/798 (50.63%), Query Frame = 2 Query: 8291 GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNME----PSLQP-VKELK--NAVGQ-------IIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSL--QANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCA-----GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 + E I F RC + G LL G+S Y ++ +N H P+ S +++ EI+EVHKR + L+ AVE+FL +GR LLAF K ++ +Y H+I + + +E + S ++TQ W +I+NF+YL +LN AGRS+NDLMQYPVFP+IL DY SETLDL P+ +R L KP+ QS+ + ++ YR DDP PYHYG+HYS++ V +LVRM PFT+ FL Q FD+ DR FHS+ TW +S +M D+KELIPEFFYLP FL N FD G +QN + + LPPWA+ D R F+ HR+ALE D VS L +WIDL+FG KQ G AA+ A+NVFH Y G +D+ +++DP++R A+ I +GQ P+QLF H ++ P ++ ++ P A + F + + + PS P +K LK VG + + +G ++ ++P+ + K + +Y++ ++WG++D LR+ + S+ I + + C + L TG V+ ++ +R + +A + + Q +LYGH + VT L V Y++L+S SRD TCI+WDL R+CY++ L+GH +PV A+ SE TG +A+ G+ L LW+++G+ + V+ + I +V S + NV+ G +GVVR+WS Sbjct: 2905 ATSEPIRFTRRCISVAPSRETAGELLLGKSGMYFVE-------------DNAAETPHGETEPA-------------SFCWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVY---------------HNILTSELPNLLEYDNIS---------ALTQLWGSSQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILRDYVSETLDLQDPNIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFVLIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAIHAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFNATHISRA--GPKLMMEGEL----PAAMGLLVQLAFRESREQAKEVTYPSPLPWIKGLKWGEYVGSPSAPDPVVCFSQPHGERFGSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYTDNMLRLKSKQSEPPINFIQCSPLHQVTSCAWVPDGCQLFTGSKCGVITAYS---------------NRFSTTMASEMDVESQVHLYGHTDEVTGLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLTGHKSPVNAVSASETTGDIATVCDSVGGGSDLRLWTVNGDLIGHVHC----REIICSVAFSNQPEGVSVNVIAGGLENGVVRLWS 3626
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: nbeal1 (neurobeachin-like 1 [Source:ZFIN;Acc:ZDB-GENE-130530-544]) HSP 1 Score: 380.563 bits (976), Expect = 4.961e-105 Identity = 241/638 (37.77%), Postives = 333/638 (52.19%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQ-NGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLI-------------------------PPLYTRYVAWGFS-------------------------DGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNER--ILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGR 10279 K+ +IRE+H RRY L+ A+E+FL D N+ L F K+++NK+Y++ + + SL L+ S + +TQ+W EISNF YLM LNT+AGR+YN+L QYPVFPWILADY SE LDL+ P FR L KP+ +E ++Y ++DP+G +HYGTHYS+A V YL+R+EPFT ++LQ G FD ADR FHSI TW++ N D+KELIPEFFY P FL N N FDLG Q + + D++LP WAK +FI HR+ALE +YVSAHL+EWIDLIFGYKQ G AAVEA+NVF++ YEG VD+ +I D +R A+ G I+NFGQ P QL K+PHP + L + ++D PL +F H + ++ + + V ++ N ++S P +++ V QN CLI P R++A FS D SLRV + K + Y + DI+ L + LI+G T VW + P GL+P LQ LYGH + V + ++ ++ VSG+RD T I+ + R Sbjct: 1977 KWPLSQIREIHLRRYNLRRSALEIFLIDQTNYFLNFKKEVRNKVYSRML-LLCSLPLHGTRSPQ-----------------ELLKASGLTQKWVNREISNFDYLMQLNTIAGRTYNNLAQYPVFPWILADYTSEELDLSDPCVFRDLSKPVAVLNEKNAKAVREKYESFEDPTGTIDRFHYGTHYSNAAGVMHYLIRVEPFTSLHIQLQSGRFDCADRQFHSIPATWQTLID-NPNDVKELIPEFFYFPEFLENQNGFDLGRLQISKERVNDVVLPKWAK-SPEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCTYEGAVDLDAITDEKERKALEGMISNFGQTPCQLLKEPHPVRLSLEELEKRTSRLDS-CPL-------NVFEHLTELKSFFVEGISDNCALVKAVVPK--NQSHSFISQGSPDTLVTVSQN-CLIGAHGWLPYDKTISNYFTFIKDPTVASPKTQRFLAGPFSPGVDVTARLFVVSHDGKLLFSGGHWDNSLRVTSLLKGKTVGQYIR---HMDIITCLATDYCGIHLISGSRDTTCMVWQVQQQGGAPV-----------GLSPK-PLQV-LYGHTDEVVSVCISTELDMAVSGARDGTVIIHSVRR 2567
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: nbeal2 (neurobeachin-like 2 [Source:NCBI gene;Acc:100330830]) HSP 1 Score: 366.696 bits (940), Expect = 6.733e-101 Identity = 221/599 (36.89%), Postives = 319/599 (53.26%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQ-NGVVLGDILLPPWAKGDSRE-FIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNME---PSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPS-----------SVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL 10273 K ++REVH RRY L+ A+E+F D ++ + F KK++NK+Y++ + G + + GS S + ++TQ+W EISNF+YLM LNT+AGR+YNDL QYPVFPW+L DY S LDL P+ FR L KP+G + ++Y ++DP+G +HYGTHYS+A V Y++RMEPFT ++LQ G FD ADR FHS+ W+ A + AD+KELIPEFFY P FL+N N F+LG Q N + +++LP WA SRE FIR HR+ALE ++VSAHL+EWIDLIFGYKQ G AVEA+NVF++ YEG VD+ +I + +R A+ G I+NFGQ P QL K+ HP + S +ID + P + LD + P +Q V IIQ + +A G + + + ++ + P R+++ FS G +++ G + V+ + R+L +GG W+ S+ + G + HI+ VTCL++ L+SGSRD TC++W + Sbjct: 2036 KRPLSQLREVHLRRYNLRRSALELFFIDQAHYFINFRKKVRNKVYSRIL---------------GLRPPNLFYFGSRSP-QELLKASNLTQKWVCREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSSVLDLEDPAVFRDLSKPIGVVNPRHAQNVREKYESFEDPTGTVDKFHYGTHYSNAAGVMHYMIRMEPFTTLHIQLQSGKFDCADRQFHSVAAAWQ-ARMESPADVKELIPEFFYFPEFLDNMNGFNLGCLQVNQEQVNNVVLPRWA--SSREDFIRKHRKALESEHVSAHLHEWIDLIFGYKQRGPEAVEALNVFYYCTYEGAVDLDAIANETERKALEGIISNFGQTPCQLLKEAHPPRMSAENASRRQSRIDTLPP---------NLFEQLDKLRDGVPLVQAVVPRNQTRSFIIQGSDVLVSVSANGQIGTHSWLPYDKNIANYFTFSKDPTMSNPKTQRFLSGPFSPG------------VEI-------GAQVLVVSSDGRLLFSGGH------WDCSLRVTMLGKGKMVG---------------RICRHIDVVTCLSLDLCGIYLISGSRDTTCMVWQV 2566
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: lrba (LPS-responsive vesicle trafficking, beach and anchor containing [Source:ZFIN;Acc:ZDB-GENE-090311-19]) HSP 1 Score: 365.54 bits (937), Expect = 1.758e-100 Identity = 235/727 (32.32%), Postives = 363/727 (49.93%), Query Frame = 2 Query: 8459 HEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPIS--IINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQAD-LNGTNSNAVGSVPSSVLAV------EQNKCLIPPLYTRYVAW-GFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSA 10585 H S P + + + K+ F EIR V RRYLLQ A+E+FL + + F K K + + + + G Q +I S + S+TQRW++ EISNF+YL++LNT++GR++NDL QYPVFPW++ +Y++E LDLT PS +R L KP+GA + R F R+ W+D + P +HYGTHYS+A +L+R+EPFT FL QGG FD ADR F SI W + Q + +D+KELIPEFFYLP N+N ++LG +G V+ D+ LPPWAK EF+R +R ALE ++VS L++WIDLIFGYKQ G AV ++NVF++L YEG V++ +I DP+ R AV I +FGQ P QL +PH + + ++ + Q+ + P+ H N +P L + ++ + +G ++ VGS + + ++C I R++ GF D S RV + D+ KL+++ +G V CL + +++G + +W S G + G + ++ +A L GH VTC +V A C +W R L G P +E ++ G + +SI+G+ L + K++ + ++ D G ++ GG G++ +W + ++ S C A Sbjct: 1960 HPSFTQSDPKI--LAYTEGLHGKWLFTEIRAVFSRRYLLQNTALEIFLANRTAVMFNFADAATVK---KVVHCLPRVGVGTNY---GLPQTRRI---SLATPKQLFKASSMTQRWQRREISNFEYLIFLNTISGRTFNDLNQYPVFPWVITNYDTEDLDLTLPSNYRDLSKPIGALNPKRAAFFSDRFESWEDE--QVPKFHYGTHYSTASFTMMWLLRIEPFTTFFLNFQGGKFDHADRTFSSISRAWRNC-QRDTSDVKELIPEFFYLPEMFVNSNNYNLGVMDDGTVVSDVELPPWAKS-PEEFVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRSLNVFYYLTYEGAVNLSTITDPMLREAVESQIRSFGQTPCQLLIEPHSPRSSAMQVTPLMFTDQMQQDVIMVLKFPSNSPVVHVAANTQPGLNSPAIITVTANRLFAVNKWHGLTASNVGSHRRQITDLLDQSIQVSSQCFIITSDNRFLLLAGFWDKSFRVYSTDTGKLVQIV-----FGHRDVVTCLARSESYIGGDCYVLSGSRDATLLLWYWS------------GKHCSIGDSKFVTPRAILTGHDCEVTCASVCAD-----------CCGLW--------RVLRGVCGPRLLQASTEGHCVIYYDQGHFC-TYSINGKLL--------QHKELEDKIRAMLLSKD-GQYLLCGGDGGILSVWQVHDLKQLFSYPGCDA 2625
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000320.1 (pep scaffold:Pmarinus_7.0:GL481331:460:21348:1 gene:ENSPMAG00000000288.1 transcript:ENSPMAT00000000320.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 691.419 bits (1783), Expect = 0.000e+0 Identity = 338/560 (60.36%), Postives = 419/560 (74.82%), Query Frame = 2 Query: 8447 PIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESET--LDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPA-ERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNAS--KPTAS 10111 P + +P++P T + +H ++ KFS+ +REVHKRRYLLQP+AVEVF DGRN+LL FP+ ++NK+Y +F+ +A SL ++ S+SGQ N+ +EAGS + S +GE+SVTQRW GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE LDLT P TFR + KPMGAQ+ RL QF+KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS++D W SAS++NMAD+KELIPEFFYLP+FL N+N ++LG KQNG+ LG++LLP WAKGD+REFIR HREALECDYVSAHL+EWIDLIFG KQ G AV + NVFHHLFYEG VDIYSI DPLK +A IGFINNFGQIPKQLFKKPHP KR + +K P AS+ PA + LF+H+LD + PS P+KELK VGQI+ + VLAVE+NK L+PP + R +WGF+D S R+ NYD+DK V+E +G ++C +C + + ++ GG +TV+ VW M KPT Sbjct: 1 PPRLQDPVIPRG-TRSPPSHPQRACSKFSYEGVREVHKRRYLLQPMAVEVFSNDGRNYLLVFPRGVRNKVYQRFLTIAPSLA-DSSESVSGQNPNASVEAGS-GLLSGLVGERSVTQRWVHGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYQSEEQELDLTDPRTFRDMSKPMGAQTMERLEQFQKRYQDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQTFLRLQGGHFDLADRMFHSVRDAWLSASRNNMADVKELIPEFFYLPDFLQNSNHYNLGCKQNGIWLGEVLLPNWAKGDAREFIRVHREALECDYVSAHLHEWIDLIFGCKQQGPMAVASTNVFHHLFYEGQVDIYSITDPLKLTATIGFINNFGQIPKQLFKKPHPAKR------VGSKPSGDTNPGASAGPARDCLFFHHLDCLTPSPVPLKELKGPVGQIVCTE-------------RGVLAVEENKVLLPPGFQRTFSWGFADLSCRLCNYDTDKAPVVFECMWEWGPLLCAVCPDAKTVVCGGTATVLCVWEMQGGGKDRKPTVG 538
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000322.1 (pep scaffold:Pmarinus_7.0:GL481331:12961:21303:1 gene:ENSPMAG00000000288.1 transcript:ENSPMAT00000000322.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 558.14 bits (1437), Expect = 9.166e-180 Identity = 276/440 (62.73%), Postives = 332/440 (75.45%), Query Frame = 2 Query: 8804 EKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESET--LDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSG-ETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPA-ERLFYHNLDNMEPSLQPVK----------ELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNM 10081 + GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE LDLT P TFR + KPMGAQ+ RL QF+KRY++W+DP+G ETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS++D W SAS++NMAD+KELIPEFFYLP+FL N+N ++LG KQNG+ LG++LLP WAKGD+REFIR HREALECDYVSAHL+EWIDLIFG KQ G AV + NVFHHLFYEG VDIYSI DPLK +A IGFINNFGQIPKQLFKKPHP KR + +K P AS+ PA + LF+H+LD + PS P+K +LK VGQI+ + VLAVE+NK L+PP + R +WGF+D S R+ NYD+DK V+E +G ++C +C + + ++ GG +TV+ VW M Sbjct: 1 QHGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYQSEEQELDLTDPRTFRDMSKPMGAQTMERLEQFQKRYQDWEDPNGSETPAYHYGTHYSSAMIVASYLVRMEPFTQTFLRLQGGHFDLADRMFHSVRDAWLSASRNNMADVKELIPEFFYLPDFLQNSNHYNLGCKQNGIWLGEVLLPNWAKGDAREFIRVHREALECDYVSAHLHEWIDLIFGCKQQGPMAVASTNVFHHLFYEGQVDIYSITDPLKLTATIGFINNFGQIPKQLFKKPHPAKR------VGSKPSGDTNPGASAGPARDCLFFHHLDCLTPSPVPLKDHYLFILSICQLKGPVGQIVCTE-------------RGVLAVEENKVLLPPGFQRTFSWGFADLSCRLCNYDTDKAPVVFECMWEWGPLLCAVCPDAKTVVCGGTATVLCVWEM 421
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008664.1 (pep scaffold:Pmarinus_7.0:GL477107:533344:566732:-1 gene:ENSPMAG00000007824.1 transcript:ENSPMAT00000008664.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 501.13 bits (1289), Expect = 1.975e-148 Identity = 428/1501 (28.51%), Postives = 695/1501 (46.30%), Query Frame = 2 Query: 2687 SIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCR--YQPHNCAEFKLDKNGSGQDFC--TYISQ-MQRP-NGGPISLTRVKSLIGITTQ-QNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPC-----EMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITS-VYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIG----NFQNPILDYENPIGS----LVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLES--LNSLPARKLIMDFFKMIIVDYFSLPKNSYQH--VIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPG-----------------GSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQL-----INGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSN----AESLWQEISTNKKQLLE 7030 + +VHP AV++ + L+P++ + LQ +++RL L +R+ Q++ E+ + LL A+ +E HPLH FERLA + P +R FLRL +PL C ++ D+ T + + P + F YIS+ + RP G + LTR+K L+ +TT + + VP P F+E +M EGFGCLFLPS+APQ+ G S + G RVFPP G S+S W+CV++ S + HP+RLL+L R GS+ ++CL +S++ + +L+ T+E++ QE ++ ++ C L QE W HLVL +R G++K SS S +++GQL KL+YI + G VY Y+GT P + S L WR GPVH +EEPL + V+ I LG ++ G Q P GS LV EE++ F LY + S+ T+ +I K YN+ D +A+Q+ L E +P+ ++HNA+GHL G R++GA +IG G+R + P+ + CVGG +LLG+LAMA D E LYA K + + + +E+E GY+L++ LLK+KR LL++ L + L G+ +E G+++ SL+ F +++ DL +W H H+S VD +++SS D++ R + +L L L+ +++ ++ + PL+ +++L+ L++ D+ +GQF+ TL SE + L + D ++ + L+ RN+ F + T+ K EE+L+ LGFDW+LLF+Q +HP+TV +AMR LV+LLS + +F++G GWL T ++ + P L E +C LPGF L S LP H +P +YF L+AL L I ++P+N++ P Q + +S+ + G S ++A P C EA LL M+R +NQ E +W+ +YP+T L+F YLYH+ +V +FL L ++P + P S + T + R+ +M++ S L+ P+RKL++DF + I VD S Q ++D++LE E TQ +++QT + S+ H + D LS Q G G+Y + N I+YF RVVDK+WQ + +P ++ +++ LISQ ++R ++ + LY NR +L++LSR ++ + + + + + P N +F CL+H L+Q+ ++G + S W+ +ST + D E L R+ +WQE+ +K+ ++E Sbjct: 1 AFLVHPGAVLAAVDLLPSV-VSATDPQRAVALQCAVVDRLGLLLQSERSQQVLSEA-GLARRLLLRCCGALASEAHPLHDGLQRAFERLACHGLEPPVLRAFLRLGNPLNCA--AWDERDLLTHRVHRGLDVCHDPTSLGSGAHSHRPVSPPFGHRRYISRSLLRPAEGAALPLTRIKCLVAMTTPLHTRHNMAAVP-------------------PPFLEFDMSVEGFGCLFLPSLAPQNAPGGSSVAISPTDDSVTSGMGSAGE-RVFPPPSGLSYSVWLCVERLDSPSQAHPVRLLTLVRRSTGSDRHLACLALSLLPR-DKAVLLCTREQLL----QEMDIPKPRADDSSQDGCVRFVTPELAQEGQWHHLVLVLNR-GVLKPSSASLYVDGQLAGNTKLSYIQATPGGLGSAGGPGAPPLVYGYVGTPPGRRRSSPLAWRVGPVHLMEEPLGHAAVATIFGLGVHHTGCMQAVLQRATEGKSEPSGSATVSLVPEERLSFGLYPLSASLLTVAKIRKAYNKADSRAVAKQIGLSSNENVTPVMLLHNASGHLGGPSRTIGAAVIGNLGVRRSAARPVASSLQCVGGPALLLGLLAMAGDVEALYAATKALVCAVRASELAQREMERIRGYQLLAMLLKRKRSLLNTHSLHLALSLAGT---------VESGRER----DSLS-GLCLPAFRDLVTDLQIWFHSPYDL------------HLS-LLDHFVD--LLTESS--DVEELR-----RIMLGLQLVPKLLHVLKDHTL-PLSKATVMSIARLLSLLLQGFPSSHDMLWYGQFLASTLPTFSVSEKFVELRADEPQDDDA--LIDIESLVSARNI-FLRNQLLEVLLDLLHTSAEKACEEMLRILGFDWLLLFVQGHLHPATVTVAMRILVSLLSNGGILRRFQEGSPGGGWLDLTQALVSGQ-----------TPTVLAE----ACLLPGFSVLLSCLPSHASLPQLYFFLLALFLNRPITSVPENVQSCPPP-------------------QLDLDSIWRYSLGLPP------------SVFSAPP----------------------SVPAPCLEAVLTLLAMLRSTVNQPWQA--EEEGSWLIEYPVTQLQFLQYLYHNVGGLANVWTHPEFLGSLAATIFPYN-------------LRPHSEMNTPSH-----FAKSRSEQMVSARSSFLSQHPSRKLVVDFLRTIAVDSLLQGNVSRQSPPLLDVLLEASPERATQSQQREYQTELLLSIMGHLQSADALSEQTH---AGHRVSFIQLVDSVTGFRRGTYTAVANGIFYFAQRVVDKLWQGMFSREPRLVFNFIAELISQAKQRSQGLSLDGLYGCLNRAVLYQLSR------PRRWPAQQGVLQESLGQLLVHRNLLLGPGNYQPDFFACLLHCLLQIRMHRFVDGFGLEARSAWH---VLSTSDPDDEEASQGALCAMRSARAQLVKLVRRVWQELIGSKRAVVE 1331
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007035.1 (pep scaffold:Pmarinus_7.0:GL477366:176480:246408:1 gene:ENSPMAG00000006333.1 transcript:ENSPMAT00000007035.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 372.089 bits (954), Expect = 1.187e-110 Identity = 252/740 (34.05%), Postives = 370/740 (50.00%), Query Frame = 2 Query: 8489 VNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLA-----GRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPH------------PTKRLLI-------------------PISIINKQIDPM--APLASSAPAERLFYHN-----LDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAW-GFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTV--------VRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTY----LHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMW 10537 V + + K+ F E+ + RRYLLQ A+E+FL + + P I + + + + + + ++ S A +F ++TQRW++ ++SNF+YLM+LNT+A GR+YNDL QYPVFPW++A+Y+SE LDLT PS FR L KP+GA + R F +RY WDD + P +HYGTHYS+A V +L+R+EPFT +FL LQGG FD ADR F S+ W + SQ + +D+KELIPEFFYLP N+N ++LG GV +GD++LPPWAK EF+R +R ALE + VS L++W+DLIFGYKQ G A+ A+NV+++L YEG V++ SI D + R AV I +FGQ P QL +PH P++ ++ P++ + PM P + RLF N + S++ + L + ++ A++ + V SV + R+V GF D S RV + D+ +L + +G V CL + GG V V +W S + A G + G + S +A L GH VT +AV+ L +SGS C+M L G + LR L G A + ++ A C G Y L +S++G S T TG + + + ++ G V+TGG GVV +W Sbjct: 10 VKVLAYTESLHGKWLFSEVEAIFSRRYLLQNTALEIFLSSRTSIMFNLPDA---TIVKSVVHLLPRVGIGTLYGLPQARRYSL--ASPRQLFK----ASNMTQRWQQRDVSNFEYLMFLNTIAACTDPGRTYNDLNQYPVFPWVIANYDSEELDLTLPSNFRDLSKPVGALNPQRAAVFAERYASWDD--ADIPAFHYGTHYSTAAFVLMWLLRVEPFTNYFLSLQGGKFDHADRTFSSVARAWRN-SQRDTSDVKELIPEFFYLPEMFTNSNDYNLGVTDAGVAVGDVVLPPWAK-TGEEFVRINRAALESEIVSCQLHQWVDLIFGYKQRGPEAIRAMNVYYYLTYEGAVNMASIRDRVTREAVEAQIRSFGQTPAQLMVEPHAPRSSAMHMVWFPSQTPMMFSNKSQQEVIMVLKFPSNSPVTHVAANTGPMQSPPAILTITCSRLFAINKWNGLCERSSASMEDIMRLPVEIDPLLVANMGLHRRQIMDPVDHSVPTCVNTFTVTAD--NRFVMLGGFWDKSFRVYSTDTGRLKQAM-----FGHWDVVTCLARSEVGVGGDCYVASGSRDATVLLWRWS---GRELALGD--RTMHGNMR---SPRAILTGHDTEVTSVAVSTELGLAISGSIGSPCLMHTLAGEL--LRALEGAGATATPLLLA--ISQDALCFGYYDDGTLLSFSVNGR--LSARTPTGDTTRAMVLSAD-------GQYVLTGGDKGVVEVW 708
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008649.1 (pep scaffold:Pmarinus_7.0:GL477107:529775:566732:-1 gene:ENSPMAG00000007824.1 transcript:ENSPMAT00000008649.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 379.407 bits (973), Expect = 1.577e-107 Identity = 311/997 (31.19%), Postives = 494/997 (49.55%), Query Frame = 2 Query: 2687 SIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQ-QNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITS-VYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKIN--LNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKI----AEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLK 5644 + +VHP AV++ + L+P++ + LQ +++RL L +R+ Q++ E+ + LL A+ +E HPLH FERLA + P +R FLRL +PL C ++ D+ YQ + SG + P G + LTR+K L+ +TT + + VP P F+E +M EGFGCLFLPS+APQ+ G S RVFPP G S+S W+CV++ S + HP+RLL+L R GS+ ++CL +S++ + +L+ T+E++ + + V E L QE W HLVL +R G++K SS S +++GQL KL+YI + G VY Y+GT P + S L WR GPVH +EEPL + V+ I LG ++ G Q + + SLV EE++ F LY + S+ T+ +I K YN+ D +A+Q+ L E +P+ ++HNA+GHL G R++GA +IG G+R + P+ + CVGG +LLG+LAMA D E LYA K + + + +E+E GY+L++ LLK+KR LL++ L + L G+ +E G+++ SL+ F +++ DL +W H H+S VD +++SS D++ R + +L L L+ +++ ++ + PL+ +++L+ L++ D+ +GQF+ TL SE + L + S + ++ L+ RN+ F + T+ K+ EE+L+ LGFDW+LLF+Q +HP+TV +AMR LV+LLS + +F++G GWL T ++ + +L N P REIN ++C LPGF L S LP H +P +YF L+AL L I ++P+N++ Sbjct: 1 AFLVHPGAVLAAVDLLPSV-VSATDPQRAVALQCAVVDRLGLLLQSERSQQVLSEA-GLARRLLLRCCGALASEAHPLHDGLQRAFERLACHGLEPPVLRAFLRLGNPLNCA--AWDERDL----------YQ---------SRPPSGI--------VDNPEGAALPLTRIKCLVAMTTPLHTRHNMAAVP-------------------PPFLEFDMSVEGFGCLFLPSLAPQNAPGGSSE-------------------RVFPPPSGLSYSVWLCVERLDSPSQAHPVRLLTLVRRSTGSDRHLACLALSLLPR-DKAVLLCTREQLLQEMALKELVRHSQDGCVRFVTPE-LAQEGQWHHLVLVLNR-GVLKPSSASLYVDGQLAGNTKLSYIQATPGGLGSAGGPGAPPLVYGYVGTPPGRRRSSPLAWRVGPVHLMEEPLGHAAVATIFGLGVHHTGCMQAVL---QRATVSLVPEERLSFGLYPLSASLLTVAKIRKAYNKADSRAVAKQIGLSSNENVTPVMLLHNASGHLGGPSRTIGAAVIGNLGVRRSAARPVASSLQCVGGPALLLGLLAMAGDVEALYAATKALVCAVRASELAQREMERIRGYQLLAMLLKRKRSLLNTHSLHLALSLAGT---------VESGRER----DSLS-GLCLPAFRDLVTDLQIWFHSPYDL------------HLS-LLDHFVD--LLTESS--DVEELR-----RIMLGLQLVPKLLHVLKDHTL-PLSKATVMSIARLLSLLLQGFPSSHDMLWYGQFLASTLPTFSVSEKFVEQALPLGSTSVFRLSMEEDGAGLVSARNI-FLRNQLLEVLLDLLHTSAEKVMRRACEEMLRILGFDWLLLFVQGHLHPATVTVAMRILVSLLSNGGILRRFQEGSPGGGWLDLTQALVSGQTPTVLGFNVGRGPGGGVIPREINSEACLLPGFSVLLSCLPSHASLPQLYFFLLALFLNRPITSVPENVQ 884 HSP 2 Score: 119.783 bits (299), Expect = 8.587e-27 Identity = 98/385 (25.45%), Postives = 176/385 (45.71%), Query Frame = 2 Query: 5903 CSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQH--VIDIILE-CDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGG---SYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTD-NIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLE 7030 C EA LL M+R +NQ E +W+ +YP+T L+F YLYH+ +V +FL L ++P + + S S E+ N+ + + P+RKL++DF + I VD S Q ++D++LE E TQ +++QT + S+ H + D LS Q G S+ + +++ F RVVDK+WQ + +P ++ +++ LISQ ++R ++ + LY NR +L++LSR ++ + + + + + P N +F CL+H L+Q I + + P +T+ N+ + Q+ +KL ++ WQE+ +K+ ++E Sbjct: 912 CLEAVLTLLAMLRSTVNQPWQA--EEEGSWLIEYPVTQLQFLQYLYHNVGGLANVWTHPEFLGSLAATIFPYN----------LRPHSEMSDTAVGTERASKDGGNVSEADYFFVHH----PSRKLVVDFLRTIAVDSLLQGNVSRQSPPLLDVLLENASPERATQSQQREYQTELLLSIMGHLQSADALSEQT----HAGHRVSFIQLVDSVTGF--RVVDKLWQGMFSREPRLVFNFIAELISQAKQRSQGLSLDGLYGCLNRAVLYQLSR------PRRWPAQQGVLQESLGQLLVHRNLLLGPGNYQPDFFACLLHCLLQ------IRMHRGEHFPTRAATEGNVCRSRAQL--VKLVRRV-------WQELIGSKRAVVE 1253 HSP 3 Score: 115.161 bits (287), Expect = 2.762e-25 Identity = 49/106 (46.23%), Postives = 71/106 (66.98%), Query Frame = 2 Query: 7373 NHVSLEEARLWIPPHISVVKELMDYH------KNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPY 7672 N ++A +W+ HI+VV++L+DY + ++E + L ++W +E+E+ RERG WGP VGS LDKWMLD EGPCRMR+K++PNE+FY HY + PY Sbjct: 1358 NRKQRKDASVWMFTHIAVVRDLVDYRYKQQQERRARGQRECSVARLLAAEWGRLEAEVTRERGPWGPPVGSRLDKWMLDPTEGPCRMRRKLMPNEHFYAHYAHYPY 1463
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: BPH1 (Protein homologous to Chediak-Higashi syndrome and Beige proteins; both of which are implicated in disease syndromes in human and mouse, respectively, due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting [Source:SGD;Acc:S000000628]) HSP 1 Score: 389.808 bits (1000), Expect = 4.421e-109 Identity = 204/479 (42.59%), Postives = 301/479 (62.84%), Query Frame = 2 Query: 8276 IEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYII-DGFTLLKTREIVEINNIPIDVHEPIV-----PSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAF-PKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSK--------------IEAGSTSIFS---NFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDD-PSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK 9637 I ++ ++ I ++ C+ I GL++ EG+L+ G +Y Y + D + L+ ++I++++ + + + V P V+TF K +I V KR +LL+ +A+E+ + + +F K++++ + ++ L + S Q+ N + I + TS+FS + + ++++W +GEISNF YL+ +N LAGRS+NDL QYPVFPW++ADYES LDL +P T+R L KPMGAQSE R QF +RY + ++ P+HYGTHYSSAMIV+ YL+R++PF + FL LQGG F ADR+F S++ W SAS N D++EL PEFF+LP FL N N +D G Q+G + D++LPPWA GD + FI+ +REALE YVSAHL+EWIDLIFGYKQ GD AV++VNVF+ L Y G V++ +IDD +R A+ G I+NFGQ P Q+F++PHP K Sbjct: 1363 ILRLLKDNDSIATIWNCSLIIGLEIKEGILIHGSNYLYFVSDYYFSLEDKKILKLSEVSQESRDMTVSLINGPDVKRVSTFLKHEVFVWKLL--DITFVTKRPFLLRDVAIELLFKERVSAFFSFYNKRVRDDVLRVLNKIPKHLPADPIFSSVLQEINDRGNSIVARNGIGKASIASKFTSVFSANNSLIDGFEISKKWVRGEISNFYYLLSINILAGRSFNDLTQYPVFPWVIADYESNVLDLENPKTYRDLSKPMGAQSEKRKLQFIERYEALASLENADSAPFHYGTHYSSAMIVSSYLIRLKPFVESFLLLQGGSFGPADRLFSSLERAWSSASSENTTDVRELTPEFFFLPEFLINVNSYDFGTDQSGKKVDDVVLPPWANGDPKVFIQKNREALESPYVSAHLHEWIDLIFGYKQKGDIAVKSVNVFNRLSYPGAVNLDNIDDENERRAITGIIHNFGQTPLQIFQEPHPEK 1839
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: VPS27 (Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p) [Source:SGD;Acc:S000005289]) HSP 1 Score: 66.6254 bits (161), Expect = 6.100e-11 Identity = 28/67 (41.79%), Postives = 43/67 (64.18%), Query Frame = 2 Query: 11162 GRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCF 11362 ++ AD WI +++ C+ C +FSL R+HHCR+CG VFC + S + + L +++PVRVC CF Sbjct: 164 SKTPAD-WI---DSDACMICSKKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEPVRVCDSCF 226
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: TAF5 (Subunit (90 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification [Source:SGD;Acc:S000000402]) HSP 1 Score: 62.7734 bits (151), Expect = 9.275e-10 Identity = 84/357 (23.53%), Postives = 140/357 (39.22%), Query Frame = 2 Query: 9740 NMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQN-----KCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMP---DPYGDIMCVLCL-------------NERILITGGFSTVVRVWNMSVNASKPTASGS-------AGSRLTGGLAPALSLQA-------NLY------GHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICI-SEVTGMVASCAGTYLHLWSI-DGEELASVNTATGRSKQ-ILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEY 10678 +++ +Q VKE ++A I+ D N ++PS + QN CL R A GF D +++ + D L D D C + + + L++G VR+W+M + + + G + S L A A Q ++Y GH+ V C++ + + +GS D+TC MWD+ +R GH APV +I + + + +++W I G+ L + G K I +++ S GNV+I+GG D VR+W L+ +EP A +P + V S N + EY Sbjct: 430 DLKLEIQKVKESRDA----IKLD------NLQLALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMR---GHGKNAIYSLSYSK-----EGNVLISGGADHTVRVWDLKKAT------------TEPSAEPDEPFIGYLGDVTASINQDIKEY 756
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: PIB1 (RING-type ubiquitin ligase of the endosomal and vacuolar membranes; binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain [Source:SGD;Acc:S000002721]) HSP 1 Score: 54.299 bits (129), Expect = 1.460e-7 Identity = 25/71 (35.21%), Postives = 35/71 (49.30%), Query Frame = 2 Query: 11183 WIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFK-----------PVRVCAKCF 11362 W DE A C CK FS RRHHCR CG +FC+ C+++ ++ R+ P R C +C+ Sbjct: 14 WQADEEAHSCFQCKTNFSFLVRRHHCRCCGRIFCSSCTENFVNYNKKRVHALQKKNSDVESPPYRTCNECY 84
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: FAB1 (1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis [Source:SGD;Acc:S000001915]) HSP 1 Score: 54.6842 bits (130), Expect = 3.655e-7 Identity = 21/62 (33.87%), Postives = 36/62 (58.06%), Query Frame = 2 Query: 11177 DHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCF 11362 ++W++DE+++ C C F+ R+HHCR CG +FC+ C+ + R +RVC C+ Sbjct: 235 EYWMKDESSKECFSCGKTFNTFRRKHHCRICGQIFCSSCTL-LIDGDRFGCHAKMRVCYNCY 295
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO33951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQQ4]) HSP 1 Score: 392.119 bits (1006), Expect = 6.457e-115 Identity = 262/747 (35.07%), Postives = 376/747 (50.33%), Query Frame = 2 Query: 8528 FSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKE----LKNAVGQIIQADL-----------NGTNSNAVGS--------VPSSVLAVEQNKCLIPPLYTRYVAWGFS--------------DGSLRVGNYDSDKLIKVYEMP-------DPYGDIMCVLCLNE--RILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPAL--SLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQL-------SGHAAPVAAICISEVTGMVASCA---GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQ--VPISTSFCSAD 10588 ++ E+REVH RR+ L+ A+E FL D N+ + KK +N +Y K + + + + G+ S + + +T+RW K EISNF+YLM LNT+AGR+YNDL QYPVFPW+L DYES+ LDL++ + +R L KP+G + R+ + E RY+ ++DP+G +HYGTHYS++ V FYL+R+EPFT + L G FD ADR FHSI W+S + +D+KEL+PEFFY P FL N N FDLG Q G + + LPPWA+ EF+ HR+ALE +YVS HL++WIDLIFGYKQ G+ AVEA NVF++ YEG VD+ +I + +R A G INNFGQ P QL PHP R+ + +KQ + +S P +F H +D ++ V + L A +QA L T S +G+ S E + L R VA FS D L + D I+V+ + + D + L ++ L+TG T R+W +S GG A + S LYGH VTC+ ++ ++ VSGSRD TCI+ + YLR L S V ++ +SE G++ S L +SI+G LA ++ + + G+ V+TGG G + + SL + VPI++ + D Sbjct: 265 WALAELREVHLRRHNLRRSALEFFLVDQTNYFINCSKKARNTVYKKIMSL---------------RPPNLYYMGARSP-AQLLKASGLTERWVKREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLVDYESKDLDLSNRAVYRDLSKPIGVLNPARVKEVEDRYKHFEDPTGTIAKFHYGTHYSNSANVLFYLLRVEPFTTLHVALHSGRFDCADRQFHSIPALWDSLF-NKASDVKELVPEFFYFPEFLENLNGFDLGRLQGGARVNHVTLPPWAR-TPEEFVHKHRQALESEYVSTHLHDWIDLIFGYKQRGEKAVEAHNVFYYCTYEGAVDLDAITNEAERIATEGMINNFGQTPSQLLTTPHPV-RMTQADAAAHKQ-KALEIAGTSKPLANVFEH-VDKLKAYFVVVTDSCDPLVFAAVPRVQARLLIHHGMPDCMVTVTRSGILGNQDWLPYSKTKSRPFTFELDPALSSVKLRRTVAGPFSPDVTVTSRHFAMTQDARLIITAGHWDNTIRVFSIKGKLQSRITAHSDTVTCLSIDRDGHHLMTGSRDTTCRLWLVS---------------HVGGWAADVDKSPLQTLYGHDHEVTCVVLSWELDMAVSGSRDGTCIVHTARKGQYLRTLRPMGNEPSSAPCRVTSLGLSEFGGIIVSSNTRDARALTHYSINGRLLAQ---ERALKDDVIDIEIC-------GDFVVTGGNSGRLGIRSLHSMNLLVPITSVSLAKD 965
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO45998 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRE1]) HSP 1 Score: 305.064 bits (780), Expect = 1.448e-86 Identity = 169/372 (45.43%), Postives = 229/372 (61.56%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPN-FLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK 9637 K +I V KRRYLL+ + +E+F D +++Y L LN+Q S + Q + + + ++++T +W+ G I+NF YLMYLN+ + RS+NDL QYPVFPW++ADY S LDL P TFR L KP+GA + NRL+Q ++R R+ +P + YG+HYS+ V +YLVR+ P + L LQGG FD DR+F+SI++TWE+ + AD+KELIPEF+ FL N LG KQ+ +GD+ LP WA D +FIR +REALEC YVS LN WIDLIFGYKQ G+ A EA NVF++L YEG VD+ SI DP +R+++ I FGQ PKQLF PHP + Sbjct: 174 KCKLSQISRVVKRRYLLRHVGIEIFSKDS------------SQMY---------LVLNSQ---SDRDQFYRELLKQPDVNLDDTEQENMTLKWQNGAITNFDYLMYLNSSSDRSFNDLTQYPVFPWVIADYTSSQLDLRDPLTFRDLAKPIGALNPNRLNQLKERCRDMTEPK-----FLYGSHYSTPGYVLYYLVRVAP--EFMLCLQGGKFDQPDRLFNSIQETWENVLTGH-ADVKELIPEFYQSSGEFLVNCQNLPLGMKQDKSNVGDVELPAWAT-DCEDFIRKNREALECPYVSERLNHWIDLIFGYKQRGEEAWEADNVFYYLTYEGAVDLDSITDPNERASLESQILEFGQTPKQLFTSPHPQR 512
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO30379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0Y3]) HSP 1 Score: 291.197 bits (744), Expect = 7.540e-85 Identity = 178/492 (36.18%), Postives = 261/492 (53.05%), Query Frame = 2 Query: 8858 GRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLL---------------IPISIINKQIDP--MAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSN----AVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL----------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVS 10237 GR+Y DL QYPVFPWIL +YES+ LDL P+ +R L KP+GA + NR QF +RY WD+ + + PP+HYGTHYS+ +L+R+EPF FL LQGG FD R F S++ W++ ++ + +D+KELIPE FYLP N+N+F G +G+V+ D+ LP WA +F+ HR ALE +YVS+ ++ WIDLIFG+KQ G AV+A NVF HL YEG+VD+ SI D + R AV I +FGQ P QL PHP + +P++ + D P + + F +++ S Q +++++ I Q + GT S +G P C + R + A G+ D S + + +S KL + +G V CL + I+++G V VW+ S + TA+ ++ + P S A L GH + +TC+ V A+ L+VS Sbjct: 1 GRTYCDLNQYPVFPWILTNYESDKLDLKDPNNYRDLTKPIGALNPNRHVQFLERYASWDE-NDDIPPFHYGTHYSTCGFTLAWLIRLEPFATQFLNLQGGKFDHPGRTFCSVQRAWQNCNR-DTSDVKELIPELFYLPEMFCNSNRFTFGVDDDGMVIDDVELPSWAN-TPEQFVTIHRAALESEYVSSQIHGWIDLIFGFKQRGPEAVKATNVFFHLTYEGSVDLDSISDTVMREAVEQQIKSFGQTPSQLLLDPHPPRVTQEMQVCIFLTFKVTENVPVTYVAAHTDQHITTPAVVTISCNQCF--SVNRWLASAQSLRDVR-----IEQDPMLGTPSGRQRRQLGE-PLDQTVTPSASCFVVTCDNRTIMACGYWDNSFKCFSTESGKLTQCV-----FGHSDVVTCLVYSRHQGLAGGDAIVVSGSRDATVLVWHWSERIQRVTAASNS-------VDP--SPLAILTGHEQPITCVDVNAALGLVVS 467
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO46742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNV7]) HSP 1 Score: 246.128 bits (627), Expect = 7.787e-70 Identity = 161/489 (32.92%), Postives = 244/489 (49.90%), Query Frame = 2 Query: 9155 GHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVL---------AVEQNKCLIPPLYTRYVAWGFSDGSLRV---GNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAG--------TYLHLWSIDGEELA------SVNTAT-GRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 G+FD DR FHS+ TW +S + D+KELIPEFF+LP FL N FD G +QNGV + D+ LPPWAK + R FI HR+ALE D VS HL+ WIDLIFG+KQ G AVEA+NVFH Y G VDI SI DP+ A+ I +GQ P QLF PH + P ++ ++ L A ++ S +N + I L G NA+ S ++ L A++ + L+ + ++W +G L V G S L+ + PD + ++ + L G + + V + N + G+R+ LYGH +A+TCL V ++++VS +D I+WDL R+ Y+R L+ H+ V A+ +S +G +A+ + + L+LW+++G +A ++N R+ + L+V NV+ TG ++G +R+WS Sbjct: 2 GNFDQPDRTFHSLATTWRLSSYQSPTDVKELIPEFFFLPEFLENFEGFDFGFRQNGVRVMDVSLPPWAKNNPRLFILIHRQALETDIVSQHLHNWIDLIFGFKQTGKDAVEALNVFHPATYFG-VDINSITDPISNKALKTMIETYGQTPTQLFTYPHSPRVTRKPQALSAADTASVSSLKLDAEVASFTGTFINRFTSSFSS----ENTIVGSITDTLAGGRYNAIISHSNTTLITMYQKADAAIDSERLLLSAV----LSWAAMNGQLDVYHGGTSASPMLLMGTKTPDK----VTRCAVSRKSLFIGSSTGALSVIPVKYNQATDCGIEVQGTRV------------RLYGHTQAITCLHVCHEFSVVVSAGQDGRAIIWDLNRLSYVRSLT-HSNAVTAVSVSRTSGDIATVSNAESVGEEESDLYLWTVNGRPIAHKTCEITINCLDFSRAPEGLSV-----------NVIATGLSNGAIRLWS 453
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO29546 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3B8]) HSP 1 Score: 120.939 bits (302), Expect = 1.460e-31 Identity = 55/119 (46.22%), Postives = 77/119 (64.71%), Query Frame = 2 Query: 8798 RWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQG 9154 RW G +SNF+YL LN +AGR+ NDLMQYPVFP++L+D+ SE LDL P T R L KP+ Q+ ++++ YR+ + P HY +HYS++ V +LVR+ PFT L+ QG Sbjct: 1 RWRAGTLSNFEYLTELNKMAGRTCNDLMQYPVFPFVLSDFTSEVLDLNDPKTLRDLTKPIAVQNPIMEAKYKEYYRQQGESDPAAAPCHYSSHYSNSGTVLHFLVRLPPFTNMLLQYQG 119
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:101161316]) HSP 1 Score: 1213.75 bits (3139), Expect = 0.000e+0 Identity = 826/2676 (30.87%), Postives = 1365/2676 (51.01%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA---GISDSVNNEQDEXXXXXXXXXXXXIS-------NCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPV-------------PPSSI------------------NNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCC--------------QPITINKD-DINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXX---XXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENP--------IGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKN--TIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEK--CGNVINNIRNTEMITLESLNSL---PARKLIMDFFKMIIVDYF-SLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY 7768 MN V+RI+ + + +D L L+ LF++ + + ++ LY ++P+F+++F P + E+F D+ F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++ E ++GW+LL+ + +L+ ++CM T S+PST VKCLY+FFDLP+ Q + P RR +L F Q++ ++C + + EEL +K+DL+LLF A+ SWCP HN WR++A +VL TI+ +GLS + +++I+ K+ ++ C++N+ + L +EIV++F L L++SS V+Q LLDDFR QGY+ + + +++LE+ +E +D+++ L+ L+ L T G EL+P L+ + + GF LP P K ++RN AF VLQ+ FL A+T L +L+AI IY DPANYFILE Q+T F+E++ K Q + L++ +V +LNYVP KE+ +S+++K+ + V+ ++L H+ +F +VL+++G+LE+ VN LH YA LK +D NN E L + ++ + N LFR+ GG+ CV ++V + + + AL I+ L LS ++DM LGL+ S L LK +L +L VL+ESHR R VFRKV FV LV +E + W+ + + ++ E + + S LT A++ EP+N +F + Y L +A+R LGCF L + GV N Q + + +SV L CS+ + +++ A + FD+ ++ ++ + +P+P P PP+ I ++ ++++HP AV++++ L+P+I D +Q H ++LQ+ + L L + +RN Q++CE+ + +L A+ +E+HPLH +FERLA+Q + P +R+FLRL +PL C +P +++ D D+ S + P + + NG + S ++ G + LTRVK L+ +TT D A+ P+FVE +M EGFGCLFLP + ++ ++ + ++ G+G GER+FPP G S+STW CV++FSS HP+RLL++ R S + CL ++ +++ + ++ VSTKEE+ E+ E++ E + A F C L+ E W HLVL + GM+K+S + +++GQL++T KL+YI S + ++++VY YIGT P ++S+L WR GP F+EE L A+ + I LGPNY+G+FQ L ++ + +LV EEKV FSL A+++S T+ +I K YN+LD +A+QL + E ++P+++IHNAAGHL+G R++GA ++GY G+R F P P+ + VGG+ +LG++AMA+D E LYA VK + + N KE+E GY+L++ LLKKKR LL+S I L L G+ D + I N F +++CD +WLH H+S F+ ++ +++SSE K CR L D L+ + L++ L+ +S ++ L++ P DL RFGQF+ TL E + + NN+ +++ +F + LI +RN +L++L + T + EEL++ LGFDW+L+FM+ +H STV +A+ LV LLS + +F++G+ GWL TD VL + G +L N LREIN D+CH PGF LQ+LLP H +P++YF+L+AL L + +PD+L+ + N ++ + F+ +S+ F+FG + SG G I +C+EAA +LL M+R MLN E +W+R+YP+TL++FF YLYH+ + + ++FL L A++P + ++ + ++ E+ TE K G+ N +E + S SL PA+K + DF +++I+D + P + ++D++LE E +T+ K+FQ+ ++ + EH +A D+L G++ LPL GGSY + NN++YF RVVDK+WQ + D +++ ++ +LI Q ++R ++ +++Y NR +L++L R K + + + L T + + P N D +FV CL H I L +G N+ G+ +TW+ P I +N D + + + +W E+ +K+Q+LE+ FK+ + ++ + +E+ LK+W +++ E + R P + + S +++G +S+ + + K N +++NS S +E W+ HI+VV++L+ + +++ + Y+ +W S+E EL RERGLWGP +GS LDK++L+ EGPCRMRKKM+ N+ FY HYPY P + N Q + +++ A S D + YY Sbjct: 1 MNMVKRIMGRPRQDECSP----QDNALGLMHLRRLFSELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSSMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEVNQSE----ETSRGWMLLSTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHMTEGHPQPEL------------------PL-ADRRALLQKVFVQIMVKLCTFVSPAEELAQKDDLQLLFSAITSWCPPHNLPWRRSAGEVLNTISRHGLSVNVVKYIHEKECLATCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSGVSQTLLDDFRMCQGYSFLCDLMLRLEQGKEDEP-KDALKDLVNLVTCLCTYGVTELKPA-GLTTGAPFLLPGFVLPQPTGKGHTVRNIQAFAVLQNAFLRAKTSRLACMLLDAIGNIYAADPANYFILESQHTLSQFAERVAKLP-EAQVKYFELLEFVVFSLNYVPCKELFGVSMLLKSSTSHACSITAVRTLLKLARHDPVFSDVLREVGLLEVLVNLLHKYAALLKDPASFLSFCSADCKNNTVAEEQKQLAWLVMETLTVLLQGSNTTNTNAALFREFGGARCVHNIVKYRQCREHALLIIQQLVLSPSGDDDMGTLLGLMHSAPPSELQLKTDILRALLAVLRESHRTRTVFRKVGGFVYVTSLLVAMERSLCQPPQHGWERVNQNQVFELLHTVFSTLTAAMRYEPANSYFFRTEIQYEKLADAVRLLGCFSDTKKL----GATGVFPSNAQPFQRLLEDEAAPAGCAGDSVC---------------PTLKHCSK----------LFIYLHKMATDSFDS--------------RAEHMPPCLTHETSLPSPWGTPALTRKRHGYYGTTGPPAPIKALTDLKVHLSNPSLTGSSSSDTVVIHPGAVLAMVDLLPSITSD-SQPEHALDLQLAVANILQLLVNSERNQQVLCEAC-LHQRMLQRCSQALADEDHPLHPPLQRMFERLASQALQPVVLREFLRLGNPLNCGAWDKKLLKQYRVHKPSSLSYDTDMRNGMTMSMEGFGPDSVFATPAEDNG---QYRISRSLVRSAEGSTVPLTRVKCLVSMTTPH------------------DIHLHGSAETPAFVEFDMSLEGFGCLFLP--SLAPHNAPTNNANTSGVSDGAVLSGMGTGERLFPPPSGLSYSTWFCVERFSSAPQAHPVRLLTMVRRATSSEQHYVCLAVA-LSTKDRLLTVSTKEELLQTHSDESSEEASFYEILPCCARFRCADLIAEGQWHHLVLVMSK-GMLKNSMATLYIDGQLVNTVKLHYIHSTPGGSGSTNPPVVSTVYGYIGTPPAQRQLSSLVWRLGPSIFLEEVLPATSAAAIYELGPNYVGSFQAVYLPCKDSRAEPSPATLVALVPEEKVSFSLSAHSVSALTVAKIRKAYNKLDSKAVAKQLAVSSHENATPVKLIHNAAGHLNGPARTIGAAVVGYLGVRAFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIE--LLTESSEA-AKNCR------LLRDFQLVPK---LLLTLRDTSLSQPTVAAISNVLSLLLQGFPNPYDLLRFGQFLSSTLPTFAVCEKFVVMEINNEEKIDAGNDDDFGGLLSASLILLRNRLLDNLLRLLFITKEKCTVNAQACEELVRTLGFDWLLMFMEEHLHSSTVTVALWILVVLLSNQSILNRFKEGLSGGGWLDHTDAVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFPVLQTLLPKHTNVPELYFLLMALFLQQPVNMLPDSLQ----------VHVNITPVTSSSWTHFDLDSLWTFIFG-----------IPASSGTVVGSI-----------------------HSVCTEAAFLLLAMLRSMLNLPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWHSAEFLCALAAAVFPFN---IRPYSEMVSDLDDEAGSPTEEFKAFAGDSGMNRSQSEYCNVGSKTSLTNHPAKKYVFDFMRVLIMDNLCTTPASKQTPIVDLLLEASPERSTRTQQKEFQSNILDGVMEHLLAADVLLGEDASLPLSSGGSYQILVNNVFYFTQRVVDKLWQGMFNKDSKLVVDFIVQLIGQAKRRSQGLSLDAIYHCLNRTVLYQLCR------PHKTVAQQVALLEALRVLTVNRNLVLGPGNHDQDFVACLAHCFICLHSGSNVEGFGLEAEARMTTWHVP--ILAENEPDAVQSHDVSEGRQLLLKAVNRVWTELMHSKRQMLEDIFKVSLPCNDRGHVDIATARSALEEHALKSWQNHLAHEKKCIS-----RGEAVAPATQSKLSRVSSGFGLSKLTGVRRNKKENSLNKNS--------------------------------PSAQETFQWMFTHIAVVRDLVAMQYKEYQERQQNALKYVTEEWASIEYELLRERGLWGPPIGSHLDKFVLEMTEGPCRMRKKMVRNDMFYIHYPYIP------ETTTNSTQ--KPLRYRRAISYDSKEYY 2433 HSP 2 Score: 1151.73 bits (2978), Expect = 0.000e+0 Identity = 555/1058 (52.46%), Postives = 737/1058 (69.66%), Query Frame = 2 Query: 8255 QWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSF---------CSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRS-NMAISIDNKDKSSDEL--DEE--YVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQS 11386 Q ++ ++ EKI M+RCAR+QGLD EGLLLFG+ +FY+IDG+T+ +REI +I+ +P ++HE I+P +R S F++ +I+EVHKRRYLLQP+AVEVF DGRN+LLAF K ++NK+Y +F+ V SL ++ S+SGQ+ N+ +E GS + S +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE +DL +P +FR L KPMGAQ+++RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG LGD+LLP WAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR + +K A + + ++++F+H+LDN+ PSL PVKELK VGQI+ D +LAVEQNK L+PP +T+ AWG++D S R+ NY+SDK + VYE +G I+C +C N ++++TGG ST + VW +G++ R A +L+L+ L GH +AVTCL +++Y+++VSGSRDRTCI+WDL ++ ++ QL GH AP++A+CI+E+TG + SCAGTY+H+WSI+G ++S NT TGRS+QIL +S M +WD NV++TG +DGVVR W +E++QVP + + C + S S+ + S D S + Q+ S +M D+ + SD L DE+ +V + +E + + + + + + S V++ +LR G+ W+RQL+FRSKLTMHTA++R DNA+P+ ISSLAIS+DH I VGD RGRVF WSV ++PGRS ADHW++DE + C C +RFSLTERRHHCRNCG +FC +CS++++EI RL++ PVRVC C+Y++ ++S Sbjct: 2511 QRTENTSLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGYTMTVSREIRDIDTLPPNLHEAIIPRGARQGQSQLKRTCS-IFAYEDIKEVHKRRYLLQPMAVEVFSADGRNYLLAFQKGVRNKVYQRFLAVVPSLA-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLNNPKSFRNLAKPMGAQTDDRLTQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGAKQNGTKLGDVLLPSWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKR------VRSKANGDAAGVPPNFNSDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLVPPAWTKTFAWGYADLSCRLANYESDKALVVYECLSEWGQILCAICPNPKLILTGGTSTAICVWE----------TGTSKER-----AKSLTLKQALLGHTDAVTCLTASSAYHIVVSGSRDRTCIIWDLNKLSFVTQLRGHRAPISALCINELTGDIVSCAGTYIHVWSINGSPISSANTFTGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEPDVPDCCGENHNAADDDSSESDGDEPSLSQESRPPRDPSTGGGSQPGSAVHRPRGQSGRAGASWSMDSGSDDSHRWSDTLSIDEKDGFVFVNYSEGQTKGPHPHLAPQGQSSGPHSLHPSSVEAR------------TYNQLRAGYRWERQLVFRSKLTMHTAFDRKDNAHPAEISSLAISKDHSKILVGDGRGRVFSWSVSEQPGRSAADHWVKDELVDSCSACTVRFSLTERRHHCRNCGQLFCQRCSRYQSEIRRLKISSPVRVCQNCYYNLQHERS 3519
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: lyst (lysosomal trafficking regulator [Source:NCBI gene;Acc:101170120]) HSP 1 Score: 416.772 bits (1070), Expect = 8.125e-116 Identity = 261/796 (32.79%), Postives = 403/796 (50.63%), Query Frame = 2 Query: 8291 GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQP-----VKELK--NAVGQ-------IIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCA-----GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540 + E I F RC + G LL G+S Y ++ +N I+ +F+ +++ EI+EVHKR + L+ AVE+FL +GR LLAF K ++ ++ H+I + +E G+ + ++TQ W G+I+NF+YL +LN AGRS+NDLMQYPVFP++L+DY SETLDL + +R L KP+ QS+ + ++ YR DDP PYHYG+HYS++ V +LVRM PFT+ FL Q FD+ DR FHS+ TW +S +M D+KELIPEFFYLP FL N FD G +QNG + + LPPWA+ D R F+ HR+ALE D+VS L +WIDL+FG KQ G AAV+A+NVFH Y G +D+ +++DP++R A+ I +GQ P+QLF H ++ P ++ ++ P A + F + + + P +K +K VG + + +G ++ ++P+ + +K + +Y++ ++WG+ D LR+ + S+ I + + C + L TG V+ ++ +S P+ + Q +LYGH VT L V Y++L+S S D TCI+WDL R+CY++ L+GH +PV A+ SE TG +A+ G+ L LW+++G+ + V+ + I ++ S + NV+ G +GVVR+WS Sbjct: 3040 ATSESIRFTRRCVSVAPSRETAGELLLGKSGMYFVE-------------DNAADAQDSQILHGETEAPSFS--------WTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVF---------------HNILTSDLPNLLEYGNIT---------ALTQLWGSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFVLSDYTSETLDLQEANIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGIREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFVLIHRQALESDHVSQTLCQWIDLVFGLKQKGRAAVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFSASHMSRT--GPKLMMEGEL----PAAMGLLVQLAFRETREQAKEVVCPSPLPWIKGMKWGEFVGSPSAPDPVVCFSQPHGERFGSLLALPTRAICGLYSKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYGDNILRLKSKQSEPPINFIQCSQLHQVSSCAWVPDGCQLFTGSKCGVITAYSNRFTSSTPSEM-------------EVESQVHLYGHTGEVTNLVVCKPYSILISVSCDGTCIIWDLNRLCYVQSLTGHKSPVTAVAASETTGDIATVCHSEGGGSDLRLWTVNGDLIGHVHC----RETICSLAFSNQPEGVSVNVIAGGLENGVVRLWS 3766
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: lrba (LPS responsive beige-like anchor protein [Source:NCBI gene;Acc:101175296]) HSP 1 Score: 368.622 bits (945), Expect = 1.935e-101 Identity = 225/632 (35.60%), Postives = 335/632 (53.01%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLI-------------------------PISIINKQIDPMAPLAS--SAPAERLFYHN-LDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSG 10306 K+ F EIR V RRYLLQ A+EVF+ + L FP A +V L + G Q +I S + ++TQRW++ EISNF+YLM+LNT++GR+YNDL QYPVFPW++ +Y+SE LDLT PS FR L KP+GA + R F RY W+D + P +HYGTHYS++ +L+R+EPFT FL QGG FD ADR F S+ W + Q + +D+KELIPEF+YLP N+N ++LG ++G V+ +++LPPWAK EF+R +R ALE ++VS L++WIDLIFGYKQ G A A+NV++++ YEG V++ SI+DP+ R AV I +FGQ P QL +PHP + + P++ + P A+ + A RLF N + Q +L + +I +++ G + + + + + ++C + R++ GF D S RV + DS KL ++ +G V CL + +++G + +W + K + G T G + +A L GH VTC +V A L++SG ++ C++ + G + LR L G Sbjct: 1976 KWLFTEIRAVFSRRYLLQNTALEVFMANRTAVLFNFPDA------ATVKKVVHCLPRVGVGTSFGLPQTRRI---SLATPKQLFKASNMTQRWQRREISNFEYLMFLNTISGRTYNDLNQYPVFPWVITNYDSEELDLTLPSNFRDLSKPIGALNPKRAAFFSDRYESWED--DQVPKFHYGTHYSTSSFTLMWLLRIEPFTTFFLNFQGGKFDHADRTFSSVSRAWRNC-QRDTSDVKELIPEFYYLPEMFVNSNNYNLGVMEDGTVVSNVVLPPWAKS-PEEFVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEATRALNVYYYVTYEGAVNLSSINDPMLREAVESQIRSFGQTPCQLLIEPHPPRSSAMQVTPLMFTEQMQQDVIMVLKFPSNSPVTYVAANTQPGLTSAAIITVTANRLFAVNKWHGLTGEAQQQYQLPVEIDPLIASNV-GAHRRQISDLLDQSIQI-SSQCFVITADNRFILLCGFWDKSFRVYSTDSGKLTQIV-----FGHRDVVTCLARSESYIGGDCYILSGSRDATLLLWYWN---GKLCSIGE-----TPGSESFTTPRAILTGHDCEVTCASVCAELGLVISGCKEGPCLIHSMNGDL--LRTLEG 2577
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: nbeal2 (neurobeachin like 2 [Source:NCBI gene;Acc:101163272]) HSP 1 Score: 353.984 bits (907), Expect = 6.874e-97 Identity = 181/382 (47.38%), Postives = 246/382 (64.40%), Query Frame = 2 Query: 8498 FNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQ-NGVVLGDILLPPWAKGDSRE-FIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK 9637 F+ +R +S ++REVH RRY L+ A+E+F D ++ + F KK++NK+Y++ + G + + GS S + +TQ+W EISNF+YLM LNT+AGR+YNDL QYPVFPW+L DY S TLDL+ PS FR L KP+G + ++Y ++DP+G +HYGTHYS+A V Y++RMEPFT ++LQ G FD+ADR FHS+ W+ A + AD+KELIPEFFY P FL N N FDLG Q + + D+ LP WA SRE FIR HR+ALE ++VS+HL+EWIDLIFG KQ G+ AV A+NVF++ YEG VD+ +I + +R A G I+NFGQ P QL K+PHP++ Sbjct: 2035 FDFKRPLS------QLREVHLRRYNLRRSALELFFIDQSHYFINFKKKVRNKVYSRIL---------------GLRPPNLFYFGSRSP-QELLKASGLTQKWVYREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSPTLDLSDPSIFRDLSKPIGVVNPRHAQNVREKYESFEDPTGNIDKFHYGTHYSNAAGVMHYMIRMEPFTTLHIQLQSGRFDVADRQFHSVAAAWQ-ARMESPADVKELIPEFFYFPEFLQNMNGFDLGRLQISQEAVTDVELPRWAT--SREDFIRKHRKALESEHVSSHLHEWIDLIFGCKQRGEEAVNALNVFYYCTYEGAVDLDAIANETERKAYEGIISNFGQTPCQLLKEPHPSR 2391
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: nbeab (neurobeachin [Source:NCBI gene;Acc:101155372]) HSP 1 Score: 335.495 bits (859), Expect = 1.629e-91 Identity = 244/730 (33.42%), Postives = 366/730 (50.14%), Query Frame = 2 Query: 8504 HRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLI------------------------------PISIINKQIDP--MAPLASSAPAERLF----YHNLDNMEP----SLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGG-------LAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSGHAAPVAAICI---SEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMW 10537 H + K+ F EIR V R YLLQ A+EVF+ + + + P + A V SL + G Q +I S + ++TQRW++ EISNF+YLM+LNT+AGR+YNDL QYPVFPW+L +Y+SE LDLT P FR L KP+GA + R + +RY W+D +TP HY +HYSS +LVR+EPFT +L FD DR F SI +W S Q + +D+KELIPEF+YLP N++ ++LG +++G + D+ LP WAK +F+R +R ALE ++VS L++WIDLIFGYKQ G AV A+NVFHHL YEG+V++ I D R A I +FGQ P QL +PHP + + P++ + P P + RLF +HN + SL L + +I A+ G+N + + + + + + C + RY+ F D S RV + ++ KL ++ +G V CL GG +V + S +A+ S + G L + +A L GH + V C++V A L++SG+++ C++ + G + LR L G A + I SE ++ G + + +SI+G+ LA + +I T + ++ D G+ ++TGG +GVV +W Sbjct: 1559 HTEGLHGKWMFSEIRAVFSRCYLLQNTALEVFMANRTSVMFNLPDQ------ATVKNVVHSLPRVGVGTSYGLPQARRI---SLATPRQLFKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYDSEELDLTLPRNFRDLSKPVGALNPKRAAFYGERYGTWED--DQTPSCHYTSHYSSTSTTLHWLVRIEPFTTFYLCSNKNKFDHPDRTFSSIARSWRSC-QRDTSDVKELIPEFYYLPEMFVNSSNYNLGMREDGSRISDVELPAWAK-KPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHHLTYEGSVNLDGIGDLSLRQATEAHIQSFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDSVI-ANNTGSNKHQITDLVDQSIRITTH-CFVVTADNRYILVCSFWDKSFRVYSSETGKLTQIV-----FGHWDVVTCLARSESYIGGDCYIV---SGSRDATLLLWYWSGRHHIIDGHYHFIFLLYLCFAPRAVLTGHDQEVVCVSVCAELGLVISGAKEGPCLVHTITGDL--LRALEGPAYCLCPRLISVSSEGHCIIYYERGHFCN-FSINGKLLAQM--------EIKDSTRAIILSSD-GHNLVTGGDNGVVEVW 2253
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000039846.1 (SMESG000039846.1) HSP 1 Score: 7291.81 bits (18918), Expect = 0.000e+0 Identity = 3763/3783 (99.47%), Postives = 3767/3783 (99.58%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSDSKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISL+HLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGGFSFSTWICVQKFSS+ATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTD+VLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENME FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESI FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQI QESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQIS+KLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSAD SEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS Sbjct: 1 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSDSKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLLHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGGFSFSTWICVQKFSSMATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDVVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENME-------------FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESISFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQIIQESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISVKLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADLSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 3770
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000039846.1 (SMESG000039846.1) HSP 1 Score: 7263.69 bits (18845), Expect = 0.000e+0 Identity = 3751/3783 (99.15%), Postives = 3755/3783 (99.26%), Query Frame = 2 Query: 41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSDSKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISL+HLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGGFSFSTWICVQKFSS+ATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTD+VLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLK FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESI FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQI QESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQIS+KLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSAD SEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS Sbjct: 1 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSDSKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLLHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGGFSFSTWICVQKFSSMATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDVVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLK-------------------------FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESISFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQIIQESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISVKLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADLSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 3758
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000039846.1 (SMESG000039846.1) HSP 1 Score: 3875.86 bits (10050), Expect = 0.000e+0 Identity = 1958/1977 (99.04%), Postives = 1961/1977 (99.19%), Query Frame = 2 Query: 5459 LMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389 ++DNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENME FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESI FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQI QESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQIS+KLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSAD SEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS Sbjct: 25 IVDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENME-------------FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESISFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQIIQESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISVKLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADLSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 1988
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000017089.1 (SMESG000017089.1) HSP 1 Score: 355.91 bits (912), Expect = 1.198e-97 Identity = 174/378 (46.03%), Postives = 246/378 (65.08%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPIS 9658 K+ F EIR + R++L + IA+E+F+ + + AFP + + K I V + + ++ +S +++S SN +TQRW++ EISNF YLMYLNT+AGR+YNDL QYP+FPW+LA+YESET+DL+SPS +R L P+GA + +R F+ R++ WDD S +HYGTHYS+A V YLVR+EPFT FL LQ G FD ADR FHS+ TW++ Q + +D+KELIPEFFYLP N+N + G ++G ++ D++LP WAK +F+R +R+ALE + VS L+ WIDLIFGYKQ G A+ + NVF +L YEG+V+ I DP+ R A+ I +FGQ P QL +PHP + + +S Sbjct: 2026 KWHFSEIRAIFSRKFLHKNIALEIFVANRMAVMFAFPDQ---ETVRKVIYVLPRVGIGIKYCVSQHRKSSLASPRQIFKLSN------MTQRWQQREISNFDYLMYLNTIAGRTYNDLNQYPIFPWVLANYESETIDLSSPSNYRDLSSPIGALNPSRKKFFDNRFKNWDDDSQSA--FHYGTHYSTAAFVLNYLVRVEPFTTLFLNLQSGKFDHADRTFHSVAQTWKNC-QRDTSDVKELIPEFFYLPEMFTNSNDYRFGKSEDGNIVDDVILPKWAKT-PEDFVRINRQALESELVSCQLHHWIDLIFGYKQRGPEAIRSTNVFCYLTYEGSVNWDEIKDPMIRQALEDQIRSFGQTPSQLVTEPHPPRNSALHVS 2390
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000017089.1 (SMESG000017089.1) HSP 1 Score: 355.91 bits (912), Expect = 1.307e-97 Identity = 174/378 (46.03%), Postives = 246/378 (65.08%), Query Frame = 2 Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPIS 9658 K+ F EIR + R++L + IA+E+F+ + + AFP + + K I V + + ++ +S +++S SN +TQRW++ EISNF YLMYLNT+AGR+YNDL QYP+FPW+LA+YESET+DL+SPS +R L P+GA + +R F+ R++ WDD S +HYGTHYS+A V YLVR+EPFT FL LQ G FD ADR FHS+ TW++ Q + +D+KELIPEFFYLP N+N + G ++G ++ D++LP WAK +F+R +R+ALE + VS L+ WIDLIFGYKQ G A+ + NVF +L YEG+V+ I DP+ R A+ I +FGQ P QL +PHP + + +S Sbjct: 2026 KWHFSEIRAIFSRKFLHKNIALEIFVANRMAVMFAFPDQ---ETVRKVIYVLPRVGIGIKYCVSQHRKSSLASPRQIFKLSN------MTQRWQQREISNFDYLMYLNTIAGRTYNDLNQYPIFPWVLANYESETIDLSSPSNYRDLSSPIGALNPSRKKFFDNRFKNWDDDSQSA--FHYGTHYSTAAFVLNYLVRVEPFTTLFLNLQSGKFDHADRTFHSVAQTWKNC-QRDTSDVKELIPEFFYLPEMFTNSNDYRFGKSEDGNIVDDVILPKWAKT-PEDFVRINRQALESELVSCQLHHWIDLIFGYKQRGPEAIRSTNVFCYLTYEGSVNWDEIKDPMIRQALEDQIRSFGQTPSQLVTEPHPPRNSALHVS 2390 The following BLAST results are available for this feature:
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014717 ID=SMED30014717|Name=WD repeat and FYVE domain-containing protein 3|organism=Schmidtea mediterranea sexual|type=transcript|length=11694bpback to top protein sequence of SMED30014717-orf-1 >SMED30014717-orf-1 ID=SMED30014717-orf-1|Name=SMED30014717-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=3784bp MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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