WD repeat and FYVE domain-containing protein 3

Overview
NameWD repeat and FYVE domain-containing protein 3
Smed IDSMED30014717
Length (bp)11694
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of WD repeat and FYVE domain-containing protein 3 (SMED30014717) t-SNE clustered cells

Violin plots show distribution of expression levels for WD repeat and FYVE domain-containing protein 3 (SMED30014717) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of WD repeat and FYVE domain-containing protein 3 (SMED30014717) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for WD repeat and FYVE domain-containing protein 3 (SMED30014717) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30014717

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30014717h1SMcG0005327 Contig1351GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30014717h1SMcG0005327 Contig1351GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30014717h1SMcG0005327 Contig1351GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30014717h1SMcG0005327 Contig1351GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30014717h1SMcG0010700 Contig1351GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30014717h1SMcG0010700 Contig1351GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30014717h1SMcG0010700 Contig1351GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30014717h1SMcG0010700 Contig1351GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
nervous systemSMED30014717h1SMcG0010700 dd_Smed_v4_3398_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014717h1SMcG0010700 dd_Smed_v4_3398_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014717h1SMcG0010700 dd_Smed_v4_3398_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30014717h1SMcG0010700 dd_Smed_v4_3398_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014717h1SMcG0010700 dd_Smed_v4_3398_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751])

HSP 1 Score: 1237.25 bits (3200), Expect = 0.000e+0
Identity = 890/2784 (31.97%), Postives = 1405/2784 (50.47%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXX------------XXXXXXXXXXXXHYLKTIVSDSSFIPN---PMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD----------FCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKI--AEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRS--------PCDNNENHCQVYQIK--KFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE     Q +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+    E+ +D+++ L+ LI  LTT G  EL+P   ++    + + GF +P P  K  S+RN  AF VLQ+ FL A+T FL   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+ +    + + +K  ++   H+ IFK+V +++G+LE+ VN LH YA  LK    A     DS NN    +Q  L LL+++ LT+L+   + N  +FR+ GG+ C  ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E   S   K  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +A+R LGCF SD+  I   N    N+Q        +   L  D     SVS                 L  CS+          +  ++Y  A + FD+R                       S  +H   ++ +   + P     +KL V  SS+ +  ++I+HP A+++++ L+ ++     Q  H ++LQ+ +   L  L   +RN Q+MCE+  +   LL     A+ +E+H LH     +FERLA+Q + P  +R+FLRLA PL C            +   S+  Y+P   +       G G D          +    S ++   G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLP  +    ++  ++      I+  ++ GIG GER FPP  G S+S+W C++ FSS    HP+RLL++ R    S +   CL I ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL++T KL+Y+      S  +   ++++VYAYIGT P   +I++L WR GP HF+EE L +S V+ I  LGPNY+G+FQ    P  D +      +P+ SLV EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P+++IHN+AGHL+G+ R++GA LIGY G+R F P P+   +  VGG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL   L  R + L       P    I+  LS L++   S     +DL RFGQF+  TL      E  + +  NN+  L++    EF   +    I      + + +     + E     +   EEL+K LGFDWI++FM+  +H +TV  AMR LV LLS    ++KF++G+   GWL  TD VL  + G +L  N          +REIN D+CH PGF  LQS LP H  +P +YF+L+AL L   +  +P+NL+ + P            ISC + Q  QF+ +S+  F+FG                       G +++ I                  +C+EA  +LL M+R ML         E  +W+R+YP+TL++FF YLYH+  +  S+ M  DFL  L   ++P +           D  + S  ++   F+ ++ +  +++E C           + T   L + PA+K + DF +++I+D   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  ++I ++ +LI+Q ++R   ++ +++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G N+ G+        +TW+        PD   + +I +   Q+    +N         +W E+  +KKQ+LEE FK+      +   ++ +  P IE+  LK W +++  E                         I+ G  ++ + Q     KL+R+S    L +L+ S      SG              + +S +E   W+  HI+VV++L+D     + +++   + Y+  +W  +E EL RERGLWGP +GS LDKWML+  EGPCRMRKKM+ N+ FY HYPY P            P    E    + Q K  +++ A S D + Y              Y +L+       S NP  V++ I        + ++PE    +T + ++G          S P  GD +  ++ QD   +   I  +E+E+T N
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELP------------------LAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAES-KDALKDLVNLITSLTTYGVSELKPA-GITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAMNVFPSNTQP-------FQRLLEEDVISIESVS---------------PTLRHCSK----------LFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASV-GSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPV-SLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQGFPS----SNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPV-----------ISCRSKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTEAVFLLLGMLRSMLTSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEK----------------------KCISRGEALAPTTQS----KLSRVSSGFGLSKLTGSRRNRKESGLNK-----------HSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEY--------------YMRLA-------SGNPAIVQDAIVESSEGEAAQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSI--EEEEKTDN 2523          

HSP 2 Score: 1193.33 bits (3086), Expect = 0.000e+0
Identity = 571/1049 (54.43%), Postives = 740/1049 (70.54%), Query Frame = 2
Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDE----YDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRP----NMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+   ++  N  I  +      + ++++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STVV VW M  +  K               A  ++L+  L GH + VTC   + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT TGRS+QI+   MS M +WD  NV++TG +DGVVR W +E++QVP + +   A+  E Q    +      +   +SS+ E DE     D ++      S  ++ + A+  R+  A   D+    S    ++                S+  +DG   V  +   + ++ L   LS P   P    N  +L+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ S    RN
Sbjct: 2529 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLP----GSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAAS-CRATAAWCTDSGSDDSRRWSDQL---------------SLDEKDGFIFVNYSEG-QTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRN 3525          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751])

HSP 1 Score: 733.406 bits (1892), Expect = 0.000e+0
Identity = 343/508 (67.52%), Postives = 414/508 (81.50%), Query Frame = 2
Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQAD 9808
            ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+   ++  N  I     +   + ++++F+H+LDN+ PSL PVKELK  VGQI+  D
Sbjct:  132 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGIS----VLPGSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD 632          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: WDFY4 (WDFY family member 4 [Source:HGNC Symbol;Acc:HGNC:29323])

HSP 1 Score: 642.114 bits (1655), Expect = 0.000e+0
Identity = 335/788 (42.51%), Postives = 479/788 (60.79%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG-EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQID-PMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPI 10564
            + QV ++ ++   EK+   F    +QG  V EG+LLFG  +FYI + FTL  T ++    +   ++ +P +        FN   + + +D +S     + ++RE+ + R+LLQ IA+E+F  +G +  L F    ++K +  F     SL               K  +  T     + G ++ + Q+W+K +ISNF+YLMYLNT AGR+ ND MQYPVFPW+LADY SETL+L +P  FR L KPMGAQ++ R  +F +R++E +   G+ T   HY THYSSA+IVA YLVRM PFTQ F  LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N  + G  Q+G VLGD+ LPPWA GD R+FI  HR+ALE D+VSA+L+ WIDLIFGYKQ G AAV+AVN+FH  FY   +D+ SI DPL +S ++GF++NFGQ+PKQLF KPHP  R      +  K +  P++      P    F+++L ++ PS   VK++          K A+G I+             S   ++LAVE+NK L+PPL+ R  +WGF D S  +G+Y SDK++  +E    +G  +C +C +   ++T G STVV VW +S+   +P                 L L+  LYGH +AVTCLA + +++LLVSGS+D TCI+WDL  + ++ +L  H   ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G    I    +     WD   ++ITG  DG+VR+W  E V++ +
Sbjct: 2376 ERQVILQELL-DKEKVTQKFSLVIVQGHLVSEGVLLFGHQHFYICENFTLSPTGDVYCTRHCLSNISDPFI--------FNLCSKDRSTDHYSCQCHSYADMRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQPSL-------------KGKATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLPEFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPA-RTAAGKPLPGKDVSTPVSLPGHPQP----FFYSLQSLRPSQVTVKDMYLFSLGSESPKGAIGHIV-------------STEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCLCAVCPSPTTIVTSGTSTVVCVWELSMTKGRPR---------------GLRLRQALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSV 3108          

HSP 2 Score: 325.094 bits (832), Expect = 7.446e-88
Identity = 273/1007 (27.11%), Postives = 475/1007 (47.17%), Query Frame = 2
Query: 2687 SIIVHPEAVISLIHLIPAI-RCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISL----TRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHV-ILVSTKEEVFGNRE--QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMG-TLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPIL---DYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINP--LNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWL----TGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKET 5650
            + I+HP  V  ++ L+P +   D  Q +   E+Q  +   +  L   ++N Q+MCE+  +   L+     A++    PLHS  + +FE+LA+Q + P  +R FL L  P      T   D  +T      C                SG      +++   P      L    T+    +G +     + +  + +I+  T   +    R A  PSFVE +M  EG+GCLF+P+++    +S   SV                  R FPP GG +FS W  + +  +    HP+R L+L R L  + +   C ++S+   P+ + ++VST+E+ F   +  +       S+    +  C  LL    W HL +   +  M +H + S  L+GQ+I + K+ YI   +   F SM  +    VY YI T     + S+L WR GP +  EE ++   +  I +LGP Y GNFQ   +   D ++     VAEE+V F L+  + SI ++  I   YNE+D  +IA+++++  ++ + P+ ++ N AGHLSG+ R++GA+ +G  G+R F  +P    +D +GG  +LLG++++A D   +YA VK++ S L  N ++   L  H+ GY++++FLL+KK  LL+ RIF L++ + G+ +  F+   I                 N  +F  ++C+  LW++        + L  ++  H+ E  Q   +    ++++ +                  L+ ++I L  + ++ P  ++TII      ++   +       DL R G F+V+TL     +E +I ++      L +   + +   I +RN   +++L ++++     ++E K  EE+   LG DW LL +Q  +H ST VLA++ L+  L+ P    +FRDG+    W+     G D+V         MDN + Q     +     C LPGF  L   L HH  IP++Y ++    L   +  + D  K++
Sbjct:  826 AAIMHPGVVCIMVRLLPRLYHEDHPQLSE--EIQCSLASHIQSLVKSEKNRQVMCEA-GLLGTLMASCHRALVTSGSPLHSRLIRIFEKLASQAIEPDVLRQFLGLGIPSSLSATTKILDSSHTHRGNPGC----------------SGSQTAQGLAEGPWPAAPDAGLHPGVTQAPQPLGESQDSTTALQTALSLIS-MTSPRNLQPQRAALAPSFVEFDMSVEGYGCLFIPTLSTVMGTSTEYSVSGGIGTGAT---------RPFPPPGGLTFSCWFLISRHGAATEGHPLRFLTLVRHLARTEQPFVCFSVSLC--PDDLSLVVSTEEKEFQPLDVMEPEDDSEPSAGCQLQVRCGQLLACGQWHHLAVVVTKE-MKRHCTVSTCLDGQVIGSAKMLYIQ-ALPGPFLSMDPSAFVDVYGYIATPRVWKQKSSLIWRLGPTYLFEEAISMETLEVINKLGPRYCGNFQAVHVQGEDLDSEATPFVAEERVSFGLHIASSSITSVADIRNAYNEVDSRLIAKEMNISSRDNAMPVFLLRNCAGHLSGSLRTIGAVAVGQLGVRVFHSSPAASSLDFIGGPAILLGLISLATDDHTMYAAVKVLHSVLTSN-AMCDFLMQHICGYQIMAFLLRKKASLLNHRIFQLILSVAGTVELGFRSSAIT----------------NTGVFQHILCNFELWMN------TADNLELSLFSHLLEILQSPREGPRNAEAAHQA----------------QLIPKLIFLFNEPSLIPSKISTIIG-----ILACQLRGHFSTQDLLRIGLFVVYTLKPSSVNERQICMDGALDPSLPAGS-QTSGKTIWLRNQLLEMLLSVISSPQLHLSSESK--EEMFLKLGPDWFLLLLQGHLHASTTVLALKLLLYFLASPSLRTRFRDGLCAGSWVERSTEGVDIV---------MDNLKSQSPLPEQ---SPCLLPGFRVLNDFLAHHVHIPEVYLIVSTFFLQTPLTELMDGPKDS 1740          

HSP 3 Score: 139.043 bits (349), Expect = 1.541e-31
Identity = 158/677 (23.34%), Postives = 312/677 (46.09%), Query Frame = 2
Query:  302 VSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPP---WDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284
            VS  + ++++K    +  E+A LA  Q L         + +  G++LL  + +L+   +  +  +  + LP+  ++CLY+FF  P   ++ ++  + D                   V +       F Q+L  IC      E L+   +L+ L   +A+ C   +S   W++    VL+ I+    + S IQ++     +   L+N+++    L + E+ +    +   +++S  V+  L  +F NS+GY ++ + L++ +    +E +   +  L+ L+  LTTCG  EL+    +   I YP +EGF+     +   +++N  AF VLQ+VF  A    LC+++L  I+T++  +  N+F+LE        F E +  K   VQE    L++ +V  L+YVP + +  +  ++K       T + +++ + +   + +F ++ +D G+L + + QL   A  ++K  +   +  V + + EL  +++  +  L+    +N  + +  G       +V F+K        +  +L  ++ L+ +  +EE MS  +G + S ++Q        L    + +  + + R  FR    F   +  L  LEG    + +PP   W  +  ++ LE V   L  ++ AL  +P N  +F  N  +  L E +  LGCFG+
Sbjct:   99 VSDQLAQQLQKALVGKPAEQARLAAGQLLW-----WKGDVDQDGYLLLKSVYVLTGTDSETLGRVAESGLPALLLQCLYLFFVFP---LDKDELLESD-----------------LQVQKM------FVQMLLNICSDSQGLEGLLSGSELQSLL--IATTCLREHSCCFWKEPTFCVLRAIS-KAQNLSIIQYLQATDCVRLSLQNLSRLTDTLPAPEVSEAVSLILGFVKDSYPVSSALFLEFENSEGYPLLLKVLLRYDGLTQSEVD-PHLEELLGLVVWLTTCGRSELK----VFDSITYPQLEGFKFHHEAS-GVTVKNLQAFQVLQNVFHKASDSVLCIQVLSVIRTMWAWNARNFFLLEWTLQPISQFVEIMPLKPAPVQEHFFQLLEALVFELHYVPHEILRKVQHLIKESPGPSCTLMALQSILSIAGGDPLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKVSTPGVQDPERELTCVMLRIVVTLLKGSVRNAVVLKDHG-------MVPFIKIFLDDECYREASLSILEQLS-AINAEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILVTPKGRAAFRVSSGFNGLLSLLSDLEGS---LQEPPLQAWGAVSPRQTLELVLYTLCAVSAALHWDPVNGYFFRRNGLFEKLAEDLCLLGCFGA 723          

HSP 4 Score: 67.0106 bits (162), Expect = 9.315e-10
Identity = 101/460 (21.96%), Postives = 198/460 (43.04%), Query Frame = 2
Query: 5900 MCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSL----PARKLIMDFFKMIIVDYFSLPKNSYQHV-IDIILECDIENTTQEHMKQFQTVFMNSLTEHFM------AVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLI-----SQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLK-LNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQIC-------LKTWNSYIESENIGTAS----SHWGRISL 7171
            +C+E A +LL M++  ++Q      +E+  W + +P ++L+F + L H            +FL  L  A +P        +    N  SPE+    ++                T+E L +     PAR+ + +F ++++ +      +  Q + ++++LE   ++ T +  + FQ+  + S  E F       A     G+        + A    NI  F  ++V+K++   +  DP  I+ ++   I     +   +R     +LY S N++IL+ LS+       ++ + + L  L       ++   +F   NS+  F++CL+H L+ L       G+        ST++       +++K+    +  L  +   I+   ++LWQ++   ++Q LE+AFKI LS         IE++        LK W  Y+ SE    AS    +H  +++L
Sbjct: 1762 LCTEGALLLLEMLKATMSQPL--AGSEDGAWAQTFPASVLQF-LSLVHRTYPQDPAWRAPEFLQTLAIAAFPLGAQKGVGAESTRNTSSPEAAAEGDS----------------TVEGLQAPTKAHPARRKLREFTQLLLRELLLGASSPKQWLPLEVLLEASPDHATSQQKRDFQSEVLLSAMELFHMTSGGDAAMFRDGKEPQPSAEAAAAPSLANISCFTQKLVEKLYSGMFSADPRHILLFILEHIMVVIETASSQRDTVLSTLYSSLNKVILYCLSK------PQQSLSECLGLLSILGFLQEHWDVVFATYNSNISFLLCLMHCLLLLNERSYPEGFGLEPKPRMSTYHQVFLSPNEDVKEKREDLPSLSDVQHNIQKTVQTLWQQLVAQRQQTLEDAFKIDLSVKPGEREVKIEEVTPLWEETMLKAWQHYLASEKKSLASRSNVAHHSKVTL 2196          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: LYST (lysosomal trafficking regulator [Source:HGNC Symbol;Acc:HGNC:1968])

HSP 1 Score: 431.024 bits (1107), Expect = 7.634e-120
Identity = 253/717 (35.29%), Postives = 385/717 (53.70%), Query Frame = 2
Query: 8528 FSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQF-------EKRYREW---DDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQP-----VKELK---------NAVGQIIQADLNGTNSNAVGSVPS-SVLAVEQNKCLIPPL---------------YTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCA-----GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
            +++ EI+EVHKR + L+  AVE+FL +GR  LLAF   K+++ +Y               H+I      + +E G+ +  +N          W  G+I+NF+YL +LN  AGRS+NDLMQYPVFP+ILADY SETLDL     +R L KP+  Q + +  ++       E+ YR+    DDP     PYHYG+HYS++  V  +LVRM PFT+ FL  Q   FD+ DR FHS   TW  +S  +M D+KELIPEFFYLP FL N   FD G +QNG  +  + LPPWA+ D R FI  HR+ALE DYVS ++ +WIDL+FGYKQ G A+V+A+NVFH   Y G +D+ +++DP++R A+   I  +GQ P+QLF   H ++    P + +N  I+   P A     +  F    + ++    P     +K LK           V  +  +  +G    ++ ++P+ ++  + +N CL+                  ++  ++WG++D  LR+ +  S+  +   +    Y    C    +   L TG    V+  +     +S P+                +  Q +LYGH E +T L V   Y++L+S SRD TCI+WDL R+CY++ L+GH +PV A+  SE +G +A+       G+ L LW+++G+ +  V+      + I +V  S   +    NV+  G  +G+VR+WS
Sbjct: 3067 WTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKVRDDVY---------------HNILTNNLPNLLEYGNITALTNL---------WYTGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILADYVSETLDLNDLLIYRNLSKPIAVQYKEKEDRYVDTYKYLEEEYRKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSTNTTWRLSSFESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFILIHRQALESDYVSQNICQWIDLVFGYKQKGKASVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFHMAHVSR----PGAKLN--IEGELPAAVGLLVQFAFRETREQVKEITYPSPLSWIKGLKWGEYVGSPSAPVPVVCFSQPHGERFGSLQALPTRAICGLSRNFCLLMTYSKEQGVRSMNSTDIQWSAILSWGYADNILRLKSKQSEPPVNFIQSSQQYQVTSCAWVPDSCQLFTGSKCGVITAYTNRFTSSTPSEI-------------EMETQIHLYGHTEEITSLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLAGHKSPVTAVSASETSGDIATVCDSAGGGSDLRLWTVNGDLVGHVHC----REIICSVAFSNQPEGVSINVIAGGLENGIVRLWS 3735          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Match: LRBA (LPS responsive beige-like anchor protein [Source:HGNC Symbol;Acc:HGNC:1742])

HSP 1 Score: 387.882 bits (995), Expect = 3.994e-109
Identity = 245/639 (38.34%), Postives = 343/639 (53.68%), Query Frame = 2
Query: 8516 MSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFP-----KKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISII---------------------------NKQIDPMAPLASSAPAERLF----YHNLDNMEPSLQPVK-ELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVV---RVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSG 10306
            +  K+ F EIR +  RRYLLQ  A+E+F+ +    +  FP     KK+ N  Y   + V +S          G  Q  +I   S           ++TQRW+  EISNF+YLM+LNT+AGRSYNDL QYPVFPW++ +YESE LDLT P+ FR L KP+GA +  R   F +RY  W+D   + P +HYGTHYS+A  V  +L+R+EPFT +FL LQGG FD ADR F SI   W + SQ + +DIKELIPEF+YLP    N N ++LG   +G V+ D+ LPPWAK  S EF+  +R ALE ++VS  L++WIDLIFGYKQ G  AV A+NVF++L YEG V++ SI DP+ R AV   I +FGQ P QL  +PHP +   + +S +                           N Q     P   +  A RLF    +HNL   + ++Q    +L   +  +I ++  G +   +  +    + V  ++C +     RY+   GF D S RV + D+ +LI+V      +G    V CL       GG   ++   R   + +       SG   +  +   AP    +A L GH   VTC AV A   L++SGS++  C++  + G +  LR L G
Sbjct:  771 LHGKWLFTEIRSIFSRRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVN--YLPRVGVGTSF---------GLPQTRRISLASPR---QLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELDLTLPTNFRDLSKPIGALNPKRAAFFAERYESWED--DQVPKFHYGTHYSTASFVLAWLLRIEPFTTYFLNLQGGKFDHADRTFSSISRAWRN-SQRDTSDIKELIPEFYYLPEMFVNFNNYNLGVMDDGTVVSDVELPPWAK-TSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGSAMQVSPLMFTDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNKWHNLPAHQGAVQDQPYQLPVEIDPLIASN-TGMHRRQITDLLDQSIQV-HSQCFVITSDNRYILVCGFWDKSFRVYSTDTGRLIQVV-----FGHWDVVTCLARSESYIGGNCYILSGSRDATLLLWYWNGKCSGIGDNPGSETAAP----RAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLIHSMNGDL--LRTLEG 1378          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2])

HSP 1 Score: 787.334 bits (2032), Expect = 0.000e+0
Identity = 398/770 (51.69%), Postives = 515/770 (66.88%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRR-KMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGS--TSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQ--ANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNT-----ATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
            DNQ  +  ++   E++H MFRCARIQGL+  EGLLLFG+ +FY++DGFTLLKT+EI +++ +  ++H+PIVP   T  T   +  ++  KFS+  IREVHKRRYLLQPIA+EVF  DGRN+LLAFPKK++++++ K   +A +L+     S+ GQK N  IE      S+ S+ +G++SVTQRW  G ISNFQYLM+LNTLAGR YNDL QYP+FPW+LADY S  LD  + STFR   KPMGAQS +RL QF KR+REWDDPSGETPPY YGTHYSSAMIV  YLVR+EPFTQ FL LQGGHFDLADRMFHS+ D W SAS++NMAD+KELIPEFF LP    NTN FDLG KQNG+ + D+LLP W  GD REFIR HR+ALE DYVS+HL+EWIDLIFGYKQ G+ AV+  N+FHHLFYEG+VD   IDDPL R+A IGF+NNFGQIP QLFKKPHP K++ I     N                RLFYH + NM     P KEL++A+G I Q D  G            V+A+EQNK  I     RY+ WG  D S+R+G  D+DK + V+EM +   ++ C    +E  L  G  S  + VW ++   +KP                 LS++  + L GH +A+TCL    S+ +LVS SRD T ++W L  M  +RQL  H   V A+ +++ TG +A+   T LH+W+++GE LA +NT     A    + I+++  STM +WD  NV++ G +DG+V+++S
Sbjct: 2409 DNQTLLR-LLEQGEQLHSMFRCARIQGLETAEGLLLFGRDHFYVVDGFTLLKTKEIRDLDFLSQEMHDPIVPYPATGATQPPKSSRLCSKFSYNMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKIRDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGETPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLFKKPHPQKKVNILEGFSN---------TPGVTTSRLFYHAIHNMSAPQTPFKELRSAIGSIHQNDKIG------------VVALEQNKVFIGT--NRYITWGLPDRSVRMGQIDNDKSVCVHEMCE-VDEMTCAAAGDETTLFCGNTSGCITVWKVN---NKP-----------------LSMKKLSVLNGHSDAITCLVSCQSHAVLVSASRDLTVLVWHLSEMFLIRQLPKHPHAVLAVAVNDATGDIATACSTLLHVWTLNGELLAVLNTCDVAPAIDPQQMIISLAFSTMNEWDNDNVIMCGTSDGIVKIYS 3133          

HSP 2 Score: 691.419 bits (1783), Expect = 0.000e+0
Identity = 676/2629 (25.71%), Postives = 1195/2629 (45.45%), Query Frame = 2
Query:  122 SLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVL-IILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS----IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSL---LVKAFIRLIEHNKIFKEVLKDMGILE----ISVNQLHSYAYNLKKEQDAGISDSVNNE-QDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRA--LEFIKVLTLSSGSEEDMSNFLGLIRS-INSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQE---LLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSV-SLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFS-SIATTHPIRLLSLARSLQGSNE-----------FISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHC--WIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKY--VSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETK--------INLNENNKSDLESAE-FKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALR---EINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFG-NSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGL-------TGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQ--TVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPN---NIYYFFSRVVDKVWQENYVDDPDV----IISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGP-CRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY--CFSMSKSILKT 7801
            SL  L+  F++Y K  +S S  +D  +LL    PLFHK+       +L   F++V  F + + S++V+E+++RA +  T EA+ +I ++L+P         E KG+ +L  +  +LS     +I+     SLPST VK +Y+FFDLP             +  T+T       + +   +     L D   Q+++ +C +   +EELVRK+DL LLF    S     N+ WRK  A +L+ IA   ++ + I+++  KK +   +KN++     S     +  +  + L   L+ S+ +   LLD+F  + GY +I++FL+       +ET+ + +R+++++   L   G  E+ P+       +  +  F+LP+P     S+RN  AF +L  VFL + ++     +++ + +IY  DPANYFIL+ +    +F ++L +K  +V+ +L+ LI+  V  L+++P +E+ SL V++KT   A  T++   +V+   +LI  + I K+  +++G+L+    I       Y  N++       S S  ++ Q +L LL  D LT++I N ++N +LF +  G+  ++ +V  V  + R+  L+ +K L + + +++ + + +  ++  I  +NL +   +L++L  V++ESH+ RI FRK   F+     L+ LE  F+ +  P  D  I +E   +LE+V  I  + T++++ EPSN +YF   +++ S+T  +R    F ++  +I  E +E      W S       +L+++ +  + V  L DN +A    GN    +             C + + +++ A++ ++                      + SD  +  N     +  S ++   S++VHP A+IS++ L+P+I     ++T  I  Q Y+   L  +   +RN QIMC+ V MP  LL   +   + ENH L      L ERL+ Q +TP  +R FLRL  PLCC+ +  ++DD +   +                              ++    GGP+ L RVK+L+ + T ++Q                          PSFVE +M  EGF  L+LP                        +      ER+FPP  GFSF TWI +   S   A  HPIRLL++ R++   N             ++C      ++ +  +L+ST+E    ++   +  ++A+ +        +  Q  C  W HL + F+R  ++K S  S +LNG+ I T+KL Y++ N   +   +     SV A +GT P   + S L +R   +   EEP+TA  V  + +L P+YIGN+Q            L  EEK+VFSL A      TL +I  +Y ++D  ++++ L + P + S+P+R++ N   H  GAGR+ G +++GY G+R F+P P+  ++D +GG   + G++AMA D+E LYA +K + S +     LL    ++  Y++++ LL+ K  +L+S I  ++  +TG+AD   +            H  +++   N + F +++CDL +W                     SE  +  ++  Y  ++D    +++  R +S         L+ RI+ ++        NT  +E +  LI  I+        + + GQ +  TL    TSE++         +++E  K  +ES++     ++ + IRN    II   L NS      + ++ ++L++ LGFDW+   M P VH  T+ LA+R L+ +L+ P  + +F++G    GWL+  D V++ R  ++L  +      A+    +IN +  +  GF  L+ L+  H   P  Y+ +++LL+G  I  +                   F   C+    QF  E V   +FG NST    +S  +A  S                                 C +A   L  M+R  +        + +  W    P T+++   ++Y ++  F ++A   +F++ L       T AM   S+   + S       SP++  F                     ++  + P  +++MD  K I  D   +  +    +ID IL+ +I  +      Q    T  ++S+ EH +  D+LS     LPP     NI     NI    SR VD  W         +     + +L  + S+   + +  E +     R+ LF LSR I            +Q  +  + +T         ++++  F   L HL+  L              PD +     +DN +     + + Q+   A  +W ++   K+ L+EE FK Q  +++ +    +       W  +++S+             L    +GG  S+  +       +Q QIS K NR++  S + R ++  S++T +   S  S             +   +W+  H+S++KEL+      + +  + +  +    W   E+EL RERG+WGP   S L+K+ LD  EGP  RMR+K+IPN  FY  YP+RP+  +P           + ++ KVA S D + YY  C    +  L T
Sbjct:   10 SLLHLRKTFSEYLKIPVSGSRSNDPSRLL----PLFHKVMSMYTPQQLNAEFKEVVHFATFLCSVLVKEVRQRAASTGTIEAAQSIAEFLRPG-------TELKGYTILEAIRFLLSSEDEIMIDAACKVSLPSTLVKTIYLFFDLPAAA----------TTVTVTDLTENATETEDEMLKNNEKLHDMIGQIMEGLCRFKCVSEELVRKDDLLLLFVGTTSQVAEANNCWRKLCARLLEVIADKSITNAVIKYVIVKKCVRIFVKNLSSAPSNSHSDAQKTAESIICLSCFLKNSAYLTDQLLDEFYEADGYTVIKDFLL------KSETDNEIVRNILLMAISLVNSGKFEITPQ---YTSGLVQLPAFQLPIPAGNGLSVRNLNAFALLYHVFLESTSESTSCTVIDILHSIYTCDPANYFILDKEYPLSIFIDQLERKPHAVRVKLLELIEFAVFQLSHIPCRELISLCVLLKTEISAGKTAMCTIIVQMCFKLITVDAIIKDAFREVGLLDALCFIIRRMFEMYEKNIQNASFTVTSTSSRSQDQLKLSLLTTDLLTIIIKNNTENGKLFTECFGAKLLIEIVCEVNEEWRSSLLQLVKQLLIVAPTDQYIMHLVNTLQDRIPIENLEVMFSLLKALLGVVRESHKVRIQFRKSGGFLALSALLLGLEKRFTDL-HPAGDGRIPREQCQMLEFVHIIFKVFTLSMRFEPSNAKYFSTEITWDSITSLLRLTSIF-NESTVISIEETE------WKS---LTHTDLASEIAACHEVFRLDDNIEA----GNVPKGMPF------NIYFGCYVCRLIFNMALDNYEK---------------------MTSDIRW--NDDGASLEESIVSWTSSLLVHPGAIISMLCLLPSISASSMKWT--IAAQYYVSLLLKAILKSERNQQIMCQ-VDMPKHLLRIAEKLFLTENHILLQPFYYLLERLSYQSLTPNQLRSFLRLDSPLCCRSLDDDEDDDDDSKI------------------------------EIADNEGGPVPLQRVKALVSMMTPRDQ---------------------YIGTAPSFVEFDMSVEGFAALYLP--------------------SLAPMFSTTKAERIFPPLNGFSFCTWIYLDALSDKKADAHPIRLLTVTRAVAPPNSDPPSKKPSQTAHLACFQCQ-FSAFDRSLLISTEE---SDQPGADLEKTANFQTDKLIRITLADQVRCGEWFHLAVVFNR-SVLKSSQVSLYLNGRHISTQKLMYVAQNAGGAATQLAQ-TYSVNAVVGTLPALRRPSRLRFRLASIFLAEEPMTAETVRAVVQLQPHYIGNYQTA------STAPLFHEEKIVFSLSAAATQELTLAKIRTMYGKMDAEILSQHLGISPNDHSTPLRVLCNTISHAPGAGRTFGGVIVGYLGMRTFTPRPVPSLLDSIGGFASVYGLIAMAVDSEGLYASLKSLVSAIRSQPRLLATWNNNRSYQILAVLLEDKAKMLNSHIMHMVFNVTGTADTSRE------------HAPTIS---NPSAFEDLLCDLKVW-----------------KGAPSELHKMLLEHFYELITDHQLNNLQVVRKSS---------LLSRILLIIHDEPTMIKNT--DEIIFNLISAIMQPQCDSRSILKIGQSIAATLP---TSESECYEDSHLPFHISEIQKLFIESSDPPPEALHQVYIRNRLLNIIANFLANSNTQV--QQQMCDQLVRTLGFDWLFALMSPGVHSGTIYLALRILLLILNQPSLLARFKEGSANGGWLSEADSVVRNRAAVVLGFSVSAHGGAVGSKIDINPELSNCGGFAALEHLMAAHADKPYPYYAMLSLLVGQPISAL------------------RF---CD----QFNMELVWTHVFGLNST----SSVFEAINSA------------------------------NFCFDAIIPLFAMIRTSIYHQ----SSIHQPWTVTNPSTVVQMITFMYQNSPAFFNIAHTDEFILALFSTLIEDTNAMGVKSEVANRRSQDGGG--SPDAEYF---------------------QAFLAQPNVRIVMDLLKKICCDNLQVNTSKNDTIIDAILD-NISESGNTRKTQIACLTSLLHSVLEHTVGTDLLSSS--ALPPNTQAQNIVQIVANISLLSSRAVDAFWNGLVFGSESMRMLSTLYHLQVIASKKVNKAVNAEPITGCIMRMTLFILSRPI--------DSVPVQLSVLDALSTLVSKRYLFLSSNEAWFFASLTHLIFMLS-----------VTPDVLF--QFQDNSSSSDLDRTSAQVAMCACRVWSDVICAKQALIEETFKKQSVTDINAARALLSHSAGVYWQQFVDSQ-------------LRAIQTGG-SSAQGSAVTAKDIIQQQISSKFNRVA--SGITRFAAKRSMSTTTALPSSGSVAAWKS--TSTDKQVIFMWLRVHVSLIKELVRAQSTRYTEWHAHVRKWCLHDWHQWEAELTRERGIWGPERASKLEKFKLDLTEGPTTRMRRKLIPNRNFYHIYPFRPHLEAPS---------AKAQRAKVAISFDSKPYYETCLRHRRRTLDT 2293          

HSP 3 Score: 158.688 bits (400), Expect = 8.364e-38
Identity = 69/137 (50.36%), Postives = 97/137 (70.80%), Query Frame = 2
Query: 10979 GFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389
            G  + R L+ R+ LTMHTA+ R DN +P+PI+++A SRDHRS+YVGD  GRV+ W   +  GR  ADHW++D   + C  C+ +F+L +R+HHCRNCG +FC+ CS+ E+ I R+ + +PVRVC KCF  +  QQSS
Sbjct: 3219 GAQFVRVLVQRTALTMHTAFNRPDNVHPAPITAIAPSRDHRSLYVGDGIGRVWCWQSAEGGGR--ADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRKCFQRL--QQSS 3351          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2])

HSP 1 Score: 787.334 bits (2032), Expect = 0.000e+0
Identity = 398/770 (51.69%), Postives = 515/770 (66.88%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRR-KMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGS--TSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQ--ANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNT-----ATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
            DNQ  +  ++   E++H MFRCARIQGL+  EGLLLFG+ +FY++DGFTLLKT+EI +++ +  ++H+PIVP   T  T   +  ++  KFS+  IREVHKRRYLLQPIA+EVF  DGRN+LLAFPKK++++++ K   +A +L+     S+ GQK N  IE      S+ S+ +G++SVTQRW  G ISNFQYLM+LNTLAGR YNDL QYP+FPW+LADY S  LD  + STFR   KPMGAQS +RL QF KR+REWDDPSGETPPY YGTHYSSAMIV  YLVR+EPFTQ FL LQGGHFDLADRMFHS+ D W SAS++NMAD+KELIPEFF LP    NTN FDLG KQNG+ + D+LLP W  GD REFIR HR+ALE DYVS+HL+EWIDLIFGYKQ G+ AV+  N+FHHLFYEG+VD   IDDPL R+A IGF+NNFGQIP QLFKKPHP K++ I     N                RLFYH + NM     P KEL++A+G I Q D  G            V+A+EQNK  I     RY+ WG  D S+R+G  D+DK + V+EM +   ++ C    +E  L  G  S  + VW ++   +KP                 LS++  + L GH +A+TCL    S+ +LVS SRD T ++W L  M  +RQL  H   V A+ +++ TG +A+   T LH+W+++GE LA +NT     A    + I+++  STM +WD  NV++ G +DG+V+++S
Sbjct: 2407 DNQTLLR-LLEQGEQLHSMFRCARIQGLETAEGLLLFGRDHFYVVDGFTLLKTKEIRDLDFLSQEMHDPIVPYPATGATQPPKSSRLCSKFSYNMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKIRDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGETPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLFKKPHPQKKVNILEGFSN---------TPGVTTSRLFYHAIHNMSAPQTPFKELRSAIGSIHQNDKIG------------VVALEQNKVFIGT--NRYITWGLPDRSVRMGQIDNDKSVCVHEMCE-VDEMTCAAAGDETTLFCGNTSGCITVWKVN---NKP-----------------LSMKKLSVLNGHSDAITCLVSCQSHAVLVSASRDLTVLVWHLSEMFLIRQLPKHPHAVLAVAVNDATGDIATACSTLLHVWTLNGELLAVLNTCDVAPAIDPQQMIISLAFSTMNEWDNDNVIMCGTSDGIVKIYS 3131          

HSP 2 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 676/2629 (25.71%), Postives = 1195/2629 (45.45%), Query Frame = 2
Query:  122 SLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVL-IILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS----IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSL---LVKAFIRLIEHNKIFKEVLKDMGILE----ISVNQLHSYAYNLKKEQDAGISDSVNNE-QDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRA--LEFIKVLTLSSGSEEDMSNFLGLIRS-INSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQE---LLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSV-SLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFS-SIATTHPIRLLSLARSLQGSNE-----------FISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHC--WIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKY--VSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETK--------INLNENNKSDLESAE-FKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALR---EINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFG-NSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGL-------TGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQ--TVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPN---NIYYFFSRVVDKVWQENYVDDPDV----IISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGP-CRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY--CFSMSKSILKT 7801
            SL  L+  F++Y K  +S S  +D  +LL    PLFHK+       +L   F++V  F + + S++V+E+++RA +  T EA+ +I ++L+P         E KG+ +L  +  +LS     +I+     SLPST VK +Y+FFDLP             +  T+T       + +   +     L D   Q+++ +C +   +EELVRK+DL LLF    S     N+ WRK  A +L+ IA   ++ + I+++  KK +   +KN++     S     +  +  + L   L+ S+ +   LLD+F  + GY +I++FL+       +ET+ + +R+++++   L   G  E+ P+       +  +  F+LP+P     S+RN  AF +L  VFL + ++     +++ + +IY  DPANYFIL+ +    +F ++L +K  +V+ +L+ LI+  V  L+++P +E+ SL V++KT   A  T++   +V+   +LI  + I K+  +++G+L+    I       Y  N++       S S  ++ Q +L LL  D LT++I N ++N +LF +  G+  ++ +V  V  + R+  L+ +K L + + +++ + + +  ++  I  +NL +   +L++L  V++ESH+ RI FRK   F+     L+ LE  F+ +  P  D  I +E   +LE+V  I  + T++++ EPSN +YF   +++ S+T  +R    F ++  +I  E +E      W S       +L+++ +  + V  L DN +A    GN    +             C + + +++ A++ ++                      + SD  +  N     +  S ++   S++VHP A+IS++ L+P+I     ++T  I  Q Y+   L  +   +RN QIMC+ V MP  LL   +   + ENH L      L ERL+ Q +TP  +R FLRL  PLCC+ +  ++DD +   +                              ++    GGP+ L RVK+L+ + T ++Q                          PSFVE +M  EGF  L+LP                        +      ER+FPP  GFSF TWI +   S   A  HPIRLL++ R++   N             ++C      ++ +  +L+ST+E    ++   +  ++A+ +        +  Q  C  W HL + F+R  ++K S  S +LNG+ I T+KL Y++ N   +   +     SV A +GT P   + S L +R   +   EEP+TA  V  + +L P+YIGN+Q            L  EEK+VFSL A      TL +I  +Y ++D  ++++ L + P + S+P+R++ N   H  GAGR+ G +++GY G+R F+P P+  ++D +GG   + G++AMA D+E LYA +K + S +     LL    ++  Y++++ LL+ K  +L+S I  ++  +TG+AD   +            H  +++   N + F +++CDL +W                     SE  +  ++  Y  ++D    +++  R +S         L+ RI+ ++        NT  +E +  LI  I+        + + GQ +  TL    TSE++         +++E  K  +ES++     ++ + IRN    II   L NS      + ++ ++L++ LGFDW+   M P VH  T+ LA+R L+ +L+ P  + +F++G    GWL+  D V++ R  ++L  +      A+    +IN +  +  GF  L+ L+  H   P  Y+ +++LL+G  I  +                   F   C+    QF  E V   +FG NST    +S  +A  S                                 C +A   L  M+R  +        + +  W    P T+++   ++Y ++  F ++A   +F++ L       T AM   S+   + S       SP++  F                     ++  + P  +++MD  K I  D   +  +    +ID IL+ +I  +      Q    T  ++S+ EH +  D+LS     LPP     NI     NI    SR VD  W         +     + +L  + S+   + +  E +     R+ LF LSR I            +Q  +  + +T         ++++  F   L HL+  L              PD +     +DN +     + + Q+   A  +W ++   K+ L+EE FK Q  +++ +    +       W  +++S+             L    +GG  S+  +       +Q QIS K NR++  S + R ++  S++T +   S  S             +   +W+  H+S++KEL+      + +  + +  +    W   E+EL RERG+WGP   S L+K+ LD  EGP  RMR+K+IPN  FY  YP+RP+  +P           + ++ KVA S D + YY  C    +  L T
Sbjct:   10 SLLHLRKTFSEYLKIPVSGSRSNDPSRLL----PLFHKVMSMYTPQQLNAEFKEVVHFATFLCSVLVKEVRQRAASTGTIEAAQSIAEFLRPG-------TELKGYTILEAIRFLLSSEDEIMIDAACKVSLPSTLVKTIYLFFDLPAAA----------TTVTVTDLTENATETEDEMLKNNEKLHDMIGQIMEGLCRFKCVSEELVRKDDLLLLFVGTTSQVAEANNCWRKLCARLLEVIADKSITNAVIKYVIVKKCVRIFVKNLSSAPSNSHSDAQKTAESIICLSCFLKNSAYLTDQLLDEFYEADGYTVIKDFLL------KSETDNEIVRNILLMAISLVNSGKFEITPQ---YTSGLVQLPAFQLPIPAGNGLSVRNLNAFALLYHVFLESTSESTSCTVIDILHSIYTCDPANYFILDKEYPLSIFIDQLERKPHAVRVKLLELIEFAVFQLSHIPCRELISLCVLLKTEISAGKTAMCTIIVQMCFKLITVDAIIKDAFREVGLLDALCFIIRRMFEMYEKNIQNASFTVTSTSSRSQDQLKLSLLTTDLLTIIIKNNTENGKLFTECFGAKLLIEIVCEVNEEWRSSLLQLVKQLLIVAPTDQYIMHLVNTLQDRIPIENLEVMFSLLKALLGVVRESHKVRIQFRKSGGFLALSALLLGLEKRFTDL-HPAGDGRIPREQCQMLEFVHIIFKVFTLSMRFEPSNAKYFSTEITWDSITSLLRLTSIF-NESTVISIEETE------WKS---LTHTDLASEIAACHEVFRLDDNIEA----GNVPKGMPF------NIYFGCYVCRLIFNMALDNYEK---------------------MTSDIRW--NDDGASLEESIVSWTSSLLVHPGAIISMLCLLPSISASSMKWT--IAAQYYVSLLLKAILKSERNQQIMCQ-VDMPKHLLRIAEKLFLTENHILLQPFYYLLERLSYQSLTPNQLRSFLRLDSPLCCRSLDDDEDDDDDSKI------------------------------EIADNEGGPVPLQRVKALVSMMTPRDQ---------------------YIGTAPSFVEFDMSVEGFAALYLP--------------------SLAPMFSTTKAERIFPPLNGFSFCTWIYLDALSDKKADAHPIRLLTVTRAVAPPNSDPPSKKPSQTAHLACFQCQ-FSAFDRSLLISTEE---SDQPGADLEKTANFQTDKLIRITLADQVRCGEWFHLAVVFNR-SVLKSSQVSLYLNGRHISTQKLMYVAQNAGGAATQLAQ-TYSVNAVVGTLPALRRPSRLRFRLASIFLAEEPMTAETVRAVVQLQPHYIGNYQTA------STAPLFHEEKIVFSLSAAATQELTLAKIRTMYGKMDAEILSQHLGISPNDHSTPLRVLCNTISHAPGAGRTFGGVIVGYLGMRTFTPRPVPSLLDSIGGFASVYGLIAMAVDSEGLYASLKSLVSAIRSQPRLLATWNNNRSYQILAVLLEDKAKMLNSHIMHMVFNVTGTADTSRE------------HAPTIS---NPSAFEDLLCDLKVW-----------------KGAPSELHKMLLEHFYELITDHQLNNLQVVRKSS---------LLSRILLIIHDEPTMIKNT--DEIIFNLISAIMQPQCDSRSILKIGQSIAATLP---TSESECYEDSHLPFHISEIQKLFIESSDPPPEALHQVYIRNRLLNIIANFLANSNTQV--QQQMCDQLVRTLGFDWLFALMSPGVHSGTIYLALRILLLILNQPSLLARFKEGSANGGWLSEADSVVRNRAAVVLGFSVSAHGGAVGSKIDINPELSNCGGFAALEHLMAAHADKPYPYYAMLSLLVGQPISAL------------------RF---CD----QFNMELVWTHVFGLNST----SSVFEAINSA------------------------------NFCFDAIIPLFAMIRTSIYHQ----SSIHQPWTVTNPSTVVQMITFMYQNSPAFFNIAHTDEFILALFSTLIEDTNAMGVKSEVANRRSQDGGG--SPDAEYF---------------------QAFLAQPNVRIVMDLLKKICCDNLQVNTSKNDTIIDAILD-NISESGNTRKTQIACLTSLLHSVLEHTVGTDLLSSS--ALPPNTQAQNIVQIVANISLLSSRAVDAFWNGLVFGSESMRMLSTLYHLQVIASKKVNKAVNAEPITGCIMRMTLFILSRPI--------DSVPVQLSVLDALSTLVSKRYLFLSSNEAWFFASLTHLIFMLS-----------VTPDVL----FQDNSSSSDLDRTSAQVAMCACRVWSDVICAKQALIEETFKKQSVTDINAARALLSHSAGVYWQQFVDSQ-------------LRAIQTGG-SSAQGSAVTAKDIIQQQISSKFNRVA--SGITRFAAKRSMSTTTALPSSGSVAAWKS--TSTDKQVIFMWLRVHVSLIKELVRAQSTRYTEWHAHVRKWCLHDWHQWEAELTRERGIWGPERASKLEKFKLDLTEGPTTRMRRKLIPNRNFYHIYPFRPHLEAPS---------AKAQRAKVAISFDSKPYYETCLRHRRRTLDT 2291          

HSP 3 Score: 158.688 bits (400), Expect = 8.224e-38
Identity = 69/137 (50.36%), Postives = 97/137 (70.80%), Query Frame = 2
Query: 10979 GFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389
            G  + R L+ R+ LTMHTA+ R DN +P+PI+++A SRDHRS+YVGD  GRV+ W   +  GR  ADHW++D   + C  C+ +F+L +R+HHCRNCG +FC+ CS+ E+ I R+ + +PVRVC KCF  +  QQSS
Sbjct: 3217 GAQFVRVLVQRTALTMHTAFNRPDNVHPAPITAIAPSRDHRSLYVGDGIGRVWCWQSAEGGGR--ADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRKCFQRL--QQSS 3349          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2])

HSP 1 Score: 786.949 bits (2031), Expect = 0.000e+0
Identity = 398/770 (51.69%), Postives = 515/770 (66.88%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRR-KMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGS--TSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQ--ANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNT-----ATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
            DNQ  +  ++   E++H MFRCARIQGL+  EGLLLFG+ +FY++DGFTLLKT+EI +++ +  ++H+PIVP   T  T   +  ++  KFS+  IREVHKRRYLLQPIA+EVF  DGRN+LLAFPKK++++++ K   +A +L+     S+ GQK N  IE      S+ S+ +G++SVTQRW  G ISNFQYLM+LNTLAGR YNDL QYP+FPW+LADY S  LD  + STFR   KPMGAQS +RL QF KR+REWDDPSGETPPY YGTHYSSAMIV  YLVR+EPFTQ FL LQGGHFDLADRMFHS+ D W SAS++NMAD+KELIPEFF LP    NTN FDLG KQNG+ + D+LLP W  GD REFIR HR+ALE DYVS+HL+EWIDLIFGYKQ G+ AV+  N+FHHLFYEG+VD   IDDPL R+A IGF+NNFGQIP QLFKKPHP K++ I     N                RLFYH + NM     P KEL++A+G I Q D  G            V+A+EQNK  I     RY+ WG  D S+R+G  D+DK + V+EM +   ++ C    +E  L  G  S  + VW ++   +KP                 LS++  + L GH +A+TCL    S+ +LVS SRD T ++W L  M  +RQL  H   V A+ +++ TG +A+   T LH+W+++GE LA +NT     A    + I+++  STM +WD  NV++ G +DG+V+++S
Sbjct: 2409 DNQTLLR-LLEQGEQLHSMFRCARIQGLETAEGLLLFGRDHFYVVDGFTLLKTKEIRDLDFLSQEMHDPIVPYPATGATQPPKSSRLCSKFSYNMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKIRDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGETPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLFKKPHPQKKVNILEGFSN---------TPGVTTSRLFYHAIHNMSAPQTPFKELRSAIGSIHQNDKIG------------VVALEQNKVFIGT--NRYITWGLPDRSVRMGQIDNDKSVCVHEMCE-VDEMTCAAAGDETTLFCGNTSGCITVWKVN---NKP-----------------LSMKKLSVLNGHSDAITCLVSCQSHAVLVSASRDLTVLVWHLSEMFLIRQLPKHPHAVLAVAVNDATGDIATACSTLLHVWTLNGELLAVLNTCDVAPAIDPQQMIISLAFSTMNEWDNDNVIMCGTSDGIVKIYS 3133          

HSP 2 Score: 691.419 bits (1783), Expect = 0.000e+0
Identity = 676/2629 (25.71%), Postives = 1195/2629 (45.45%), Query Frame = 2
Query:  122 SLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVL-IILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS----IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSL---LVKAFIRLIEHNKIFKEVLKDMGILE----ISVNQLHSYAYNLKKEQDAGISDSVNNE-QDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRA--LEFIKVLTLSSGSEEDMSNFLGLIRS-INSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQE---LLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSV-SLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFS-SIATTHPIRLLSLARSLQGSNE-----------FISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHC--WIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKY--VSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETK--------INLNENNKSDLESAE-FKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALR---EINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFG-NSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGL-------TGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQ--TVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPN---NIYYFFSRVVDKVWQENYVDDPDV----IISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGP-CRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY--CFSMSKSILKT 7801
            SL  L+  F++Y K  +S S  +D  +LL    PLFHK+       +L   F++V  F + + S++V+E+++RA +  T EA+ +I ++L+P         E KG+ +L  +  +LS     +I+     SLPST VK +Y+FFDLP             +  T+T       + +   +     L D   Q+++ +C +   +EELVRK+DL LLF    S     N+ WRK  A +L+ IA   ++ + I+++  KK +   +KN++     S     +  +  + L   L+ S+ +   LLD+F  + GY +I++FL+       +ET+ + +R+++++   L   G  E+ P+       +  +  F+LP+P     S+RN  AF +L  VFL + ++     +++ + +IY  DPANYFIL+ +    +F ++L +K  +V+ +L+ LI+  V  L+++P +E+ SL V++KT   A  T++   +V+   +LI  + I K+  +++G+L+    I       Y  N++       S S  ++ Q +L LL  D LT++I N ++N +LF +  G+  ++ +V  V  + R+  L+ +K L + + +++ + + +  ++  I  +NL +   +L++L  V++ESH+ RI FRK   F+     L+ LE  F+ +  P  D  I +E   +LE+V  I  + T++++ EPSN +YF   +++ S+T  +R    F ++  +I  E +E      W S       +L+++ +  + V  L DN +A    GN    +             C + + +++ A++ ++                      + SD  +  N     +  S ++   S++VHP A+IS++ L+P+I     ++T  I  Q Y+   L  +   +RN QIMC+ V MP  LL   +   + ENH L      L ERL+ Q +TP  +R FLRL  PLCC+ +  ++DD +   +                              ++    GGP+ L RVK+L+ + T ++Q                          PSFVE +M  EGF  L+LP                        +      ER+FPP  GFSF TWI +   S   A  HPIRLL++ R++   N             ++C      ++ +  +L+ST+E    ++   +  ++A+ +        +  Q  C  W HL + F+R  ++K S  S +LNG+ I T+KL Y++ N   +   +     SV A +GT P   + S L +R   +   EEP+TA  V  + +L P+YIGN+Q            L  EEK+VFSL A      TL +I  +Y ++D  ++++ L + P + S+P+R++ N   H  GAGR+ G +++GY G+R F+P P+  ++D +GG   + G++AMA D+E LYA +K + S +     LL    ++  Y++++ LL+ K  +L+S I  ++  +TG+AD   +            H  +++   N + F +++CDL +W                     SE  +  ++  Y  ++D    +++  R +S         L+ RI+ ++        NT  +E +  LI  I+        + + GQ +  TL    TSE++         +++E  K  +ES++     ++ + IRN    II   L NS      + ++ ++L++ LGFDW+   M P VH  T+ LA+R L+ +L+ P  + +F++G    GWL+  D V++ R  ++L  +      A+    +IN +  +  GF  L+ L+  H   P  Y+ +++LL+G  I  +                   F   C+    QF  E V   +FG NST    +S  +A  S                                 C +A   L  M+R  +        + +  W    P T+++   ++Y ++  F ++A   +F++ L       T AM   S+   + S       SP++  F                     ++  + P  +++MD  K I  D   +  +    +ID IL+ +I  +      Q    T  ++S+ EH +  D+LS     LPP     NI     NI    SR VD  W         +     + +L  + S+   + +  E +     R+ LF LSR I            +Q  +  + +T         ++++  F   L HL+  L              PD +     +DN +     + + Q+   A  +W ++   K+ L+EE FK Q  +++ +    +       W  +++S+             L    +GG  S+  +       +Q QIS K NR++  S + R ++  S++T +   S  S             +   +W+  H+S++KEL+      + +  + +  +    W   E+EL RERG+WGP   S L+K+ LD  EGP  RMR+K+IPN  FY  YP+RP+  +P           + ++ KVA S D + YY  C    +  L T
Sbjct:   10 SLLHLRKTFSEYLKIPVSGSRSNDPSRLL----PLFHKVMSMYTPQQLNAEFKEVVHFATFLCSVLVKEVRQRAASTGTIEAAQSIAEFLRPG-------TELKGYTILEAIRFLLSSEDEIMIDAACKVSLPSTLVKTIYLFFDLPAAA----------TTVTVTDLTENATETEDEMLKNNEKLHDMIGQIMEGLCRFKCVSEELVRKDDLLLLFVGTTSQVAEANNCWRKLCARLLEVIADKSITNAVIKYVIVKKCVRIFVKNLSSAPSNSHSDAQKTAESIICLSCFLKNSAYLTDQLLDEFYEADGYTVIKDFLL------KSETDNEIVRNILLMAISLVNSGKFEITPQ---YTSGLVQLPAFQLPIPAGNGLSVRNLNAFALLYHVFLESTSESTSCTVIDILHSIYTCDPANYFILDKEYPLSIFIDQLERKPHAVRVKLLELIEFAVFQLSHIPCRELISLCVLLKTEISAGKTAMCTIIVQMCFKLITVDAIIKDAFREVGLLDALCFIIRRMFEMYEKNIQNASFTVTSTSSRSQDQLKLSLLTTDLLTIIIKNNTENGKLFTECFGAKLLIEIVCEVNEEWRSSLLQLVKQLLIVAPTDQYIMHLVNTLQDRIPIENLEVMFSLLKALLGVVRESHKVRIQFRKSGGFLALSALLLGLEKRFTDL-HPAGDGRIPREQCQMLEFVHIIFKVFTLSMRFEPSNAKYFSTEITWDSITSLLRLTSIF-NESTVISIEETE------WKS---LTHTDLASEIAACHEVFRLDDNIEA----GNVPKGMPF------NIYFGCYVCRLIFNMALDNYEK---------------------MTSDIRW--NDDGASLEESIVSWTSSLLVHPGAIISMLCLLPSISASSMKWT--IAAQYYVSLLLKAILKSERNQQIMCQ-VDMPKHLLRIAEKLFLTENHILLQPFYYLLERLSYQSLTPNQLRSFLRLDSPLCCRSLDDDEDDDDDSKI------------------------------EIADNEGGPVPLQRVKALVSMMTPRDQ---------------------YIGTAPSFVEFDMSVEGFAALYLP--------------------SLAPMFSTTKAERIFPPLNGFSFCTWIYLDALSDKKADAHPIRLLTVTRAVAPPNSDPPSKKPSQTAHLACFQCQ-FSAFDRSLLISTEE---SDQPGADLEKTANFQTDKLIRITLADQVRCGEWFHLAVVFNR-SVLKSSQVSLYLNGRHISTQKLMYVAQNAGGAATQLAQ-TYSVNAVVGTLPALRRPSRLRFRLASIFLAEEPMTAETVRAVVQLQPHYIGNYQTA------STAPLFHEEKIVFSLSAAATQELTLAKIRTMYGKMDAEILSQHLGISPNDHSTPLRVLCNTISHAPGAGRTFGGVIVGYLGMRTFTPRPVPSLLDSIGGFASVYGLIAMAVDSEGLYASLKSLVSAIRSQPRLLATWNNNRSYQILAVLLEDKAKMLNSHIMHMVFNVTGTADTSRE------------HAPTIS---NPSAFEDLLCDLKVW-----------------KGAPSELHKMLLEHFYELITDHQLNNLQVVRKSS---------LLSRILLIIHDEPTMIKNT--DEIIFNLISAIMQPQCDSRSILKIGQSIAATLP---TSESECYEDSHLPFHISEIQKLFIESSDPPPEALHQVYIRNRLLNIIANFLANSNTQV--QQQMCDQLVRTLGFDWLFALMSPGVHSGTIYLALRILLLILNQPSLLARFKEGSANGGWLSEADSVVRNRAAVVLGFSVSAHGGAVGSKIDINPELSNCGGFAALEHLMAAHADKPYPYYAMLSLLVGQPISAL------------------RF---CD----QFNMELVWTHVFGLNST----SSVFEAINSA------------------------------NFCFDAIIPLFAMIRTSIYHQ----SSIHQPWTVTNPSTVVQMITFMYQNSPAFFNIAHTDEFILALFSTLIEDTNAMGVKSEVANRRSQDGGG--SPDAEYF---------------------QAFLAQPNVRIVMDLLKKICCDNLQVNTSKNDTIIDAILD-NISESGNTRKTQIACLTSLLHSVLEHTVGTDLLSSS--ALPPNTQAQNIVQIVANISLLSSRAVDAFWNGLVFGSESMRMLSTLYHLQVIASKKVNKAVNAEPITGCIMRMTLFILSRPI--------DSVPVQLSVLDALSTLVSKRYLFLSSNEAWFFASLTHLIFMLS-----------VTPDVL----FQDNSSSSDLDRTSAQVAMCACRVWSDVICAKQALIEETFKKQSVTDINAARALLSHSAGVYWQQFVDSQ-------------LRAIQTGG-SSAQGSAVTAKDIIQQQISSKFNRVA--SGITRFAAKRSMSTTTALPSSGSVAAWKS--TSTDKQVIFMWLRVHVSLIKELVRAQSTRYTEWHAHVRKWCLHDWHQWEAELTRERGIWGPERASKLEKFKLDLTEGPTTRMRRKLIPNRNFYHIYPFRPHLEAPS---------AKAQRAKVAISFDSKPYYETCLRHRRRTLDT 2291          

HSP 3 Score: 158.688 bits (400), Expect = 8.294e-38
Identity = 69/137 (50.36%), Postives = 97/137 (70.80%), Query Frame = 2
Query: 10979 GFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389
            G  + R L+ R+ LTMHTA+ R DN +P+PI+++A SRDHRS+YVGD  GRV+ W   +  GR  ADHW++D   + C  C+ +F+L +R+HHCRNCG +FC+ CS+ E+ I R+ + +PVRVC KCF  +  QQSS
Sbjct: 3219 GAQFVRVLVQRTALTMHTAFNRPDNVHPAPITAIAPSRDHRSLYVGDGIGRVWCWQSAEGGGR--ADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRKCFQRL--QQSS 3351          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: wdfy-3 (WD40 and FYVE domain protein [Source:UniProtKB/TrEMBL;Acc:H2FLM2])

HSP 1 Score: 786.949 bits (2031), Expect = 0.000e+0
Identity = 398/770 (51.69%), Postives = 515/770 (66.88%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRR-KMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGS--TSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQ--ANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNT-----ATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
            DNQ  +  ++   E++H MFRCARIQGL+  EGLLLFG+ +FY++DGFTLLKT+EI +++ +  ++H+PIVP   T  T   +  ++  KFS+  IREVHKRRYLLQPIA+EVF  DGRN+LLAFPKK++++++ K   +A +L+     S+ GQK N  IE      S+ S+ +G++SVTQRW  G ISNFQYLM+LNTLAGR YNDL QYP+FPW+LADY S  LD  + STFR   KPMGAQS +RL QF KR+REWDDPSGETPPY YGTHYSSAMIV  YLVR+EPFTQ FL LQGGHFDLADRMFHS+ D W SAS++NMAD+KELIPEFF LP    NTN FDLG KQNG+ + D+LLP W  GD REFIR HR+ALE DYVS+HL+EWIDLIFGYKQ G+ AV+  N+FHHLFYEG+VD   IDDPL R+A IGF+NNFGQIP QLFKKPHP K++ I     N                RLFYH + NM     P KEL++A+G I Q D  G            V+A+EQNK  I     RY+ WG  D S+R+G  D+DK + V+EM +   ++ C    +E  L  G  S  + VW ++   +KP                 LS++  + L GH +A+TCL    S+ +LVS SRD T ++W L  M  +RQL  H   V A+ +++ TG +A+   T LH+W+++GE LA +NT     A    + I+++  STM +WD  NV++ G +DG+V+++S
Sbjct: 2411 DNQTLLR-LLEQGEQLHSMFRCARIQGLETAEGLLLFGRDHFYVVDGFTLLKTKEIRDLDFLSQEMHDPIVPYPATGATQPPKSSRLCSKFSYNMIREVHKRRYLLQPIALEVFSSDGRNYLLAFPKKIRDRVFDKLTSMAINLSSGGSDSLGGQKANVAIETTGRGASLLSSLIGQQSVTQRWLSGNISNFQYLMHLNTLAGRCYNDLSQYPIFPWVLADYTSSQLDFNNISTFRDFSKPMGAQSPDRLEQFLKRFREWDDPSGETPPYMYGTHYSSAMIVVSYLVRLEPFTQQFLSLQGGHFDLADRMFHSVGDAWTSASRNNMADVKELIPEFFTLPEMFTNTNHFDLGVKQNGIHVNDVLLPAWCHGDPREFIRLHRQALESDYVSSHLHEWIDLIFGYKQNGEEAVKNSNLFHHLFYEGSVDFERIDDPLTRNATIGFVNNFGQIPTQLFKKPHPQKKVNILEGFSN---------TPGVTTSRLFYHAIHNMSAPQTPFKELRSAIGSIHQNDKIG------------VVALEQNKVFIGT--NRYITWGLPDRSVRMGQIDNDKSVCVHEMCE-VDEMTCAAAGDETTLFCGNTSGCITVWKVN---NKP-----------------LSMKKLSVLNGHSDAITCLVSCQSHAVLVSASRDLTVLVWHLSEMFLIRQLPKHPHAVLAVAVNDATGDIATACSTLLHVWTLNGELLAVLNTCDVAPAIDPQQMIISLAFSTMNEWDNDNVIMCGTSDGIVKIYS 3135          

HSP 2 Score: 691.034 bits (1782), Expect = 0.000e+0
Identity = 676/2629 (25.71%), Postives = 1195/2629 (45.45%), Query Frame = 2
Query:  122 SLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVL-IILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS----IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSL---LVKAFIRLIEHNKIFKEVLKDMGILE----ISVNQLHSYAYNLKKEQDAGISDSVNNE-QDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRA--LEFIKVLTLSSGSEEDMSNFLGLIRS-INSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQE---LLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSV-SLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFS-SIATTHPIRLLSLARSLQGSNE-----------FISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHC--WIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKY--VSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETK--------INLNENNKSDLESAE-FKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALR---EINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFG-NSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGL-------TGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQ--TVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPN---NIYYFFSRVVDKVWQENYVDDPDV----IISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGP-CRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY--CFSMSKSILKT 7801
            SL  L+  F++Y K  +S S  +D  +LL    PLFHK+       +L   F++V  F + + S++V+E+++RA +  T EA+ +I ++L+P         E KG+ +L  +  +LS     +I+     SLPST VK +Y+FFDLP             +  T+T       + +   +     L D   Q+++ +C +   +EELVRK+DL LLF    S     N+ WRK  A +L+ IA   ++ + I+++  KK +   +KN++     S     +  +  + L   L+ S+ +   LLD+F  + GY +I++FL+       +ET+ + +R+++++   L   G  E+ P+       +  +  F+LP+P     S+RN  AF +L  VFL + ++     +++ + +IY  DPANYFIL+ +    +F ++L +K  +V+ +L+ LI+  V  L+++P +E+ SL V++KT   A  T++   +V+   +LI  + I K+  +++G+L+    I       Y  N++       S S  ++ Q +L LL  D LT++I N ++N +LF +  G+  ++ +V  V  + R+  L+ +K L + + +++ + + +  ++  I  +NL +   +L++L  V++ESH+ RI FRK   F+     L+ LE  F+ +  P  D  I +E   +LE+V  I  + T++++ EPSN +YF   +++ S+T  +R    F ++  +I  E +E      W S       +L+++ +  + V  L DN +A    GN    +             C + + +++ A++ ++                      + SD  +  N     +  S ++   S++VHP A+IS++ L+P+I     ++T  I  Q Y+   L  +   +RN QIMC+ V MP  LL   +   + ENH L      L ERL+ Q +TP  +R FLRL  PLCC+ +  ++DD +   +                              ++    GGP+ L RVK+L+ + T ++Q                          PSFVE +M  EGF  L+LP                        +      ER+FPP  GFSF TWI +   S   A  HPIRLL++ R++   N             ++C      ++ +  +L+ST+E    ++   +  ++A+ +        +  Q  C  W HL + F+R  ++K S  S +LNG+ I T+KL Y++ N   +   +     SV A +GT P   + S L +R   +   EEP+TA  V  + +L P+YIGN+Q            L  EEK+VFSL A      TL +I  +Y ++D  ++++ L + P + S+P+R++ N   H  GAGR+ G +++GY G+R F+P P+  ++D +GG   + G++AMA D+E LYA +K + S +     LL    ++  Y++++ LL+ K  +L+S I  ++  +TG+AD   +            H  +++   N + F +++CDL +W                     SE  +  ++  Y  ++D    +++  R +S         L+ RI+ ++        NT  +E +  LI  I+        + + GQ +  TL    TSE++         +++E  K  +ES++     ++ + IRN    II   L NS      + ++ ++L++ LGFDW+   M P VH  T+ LA+R L+ +L+ P  + +F++G    GWL+  D V++ R  ++L  +      A+    +IN +  +  GF  L+ L+  H   P  Y+ +++LL+G  I  +                   F   C+    QF  E V   +FG NST    +S  +A  S                                 C +A   L  M+R  +        + +  W    P T+++   ++Y ++  F ++A   +F++ L       T AM   S+   + S       SP++  F                     ++  + P  +++MD  K I  D   +  +    +ID IL+ +I  +      Q    T  ++S+ EH +  D+LS     LPP     NI     NI    SR VD  W         +     + +L  + S+   + +  E +     R+ LF LSR I            +Q  +  + +T         ++++  F   L HL+  L              PD +     +DN +     + + Q+   A  +W ++   K+ L+EE FK Q  +++ +    +       W  +++S+             L    +GG  S+  +       +Q QIS K NR++  S + R ++  S++T +   S  S             +   +W+  H+S++KEL+      + +  + +  +    W   E+EL RERG+WGP   S L+K+ LD  EGP  RMR+K+IPN  FY  YP+RP+  +P           + ++ KVA S D + YY  C    +  L T
Sbjct:   10 SLLHLRKTFSEYLKIPVSGSRSNDPSRLL----PLFHKVMSMYTPQQLNAEFKEVVHFATFLCSVLVKEVRQRAASTGTIEAAQSIAEFLRPG-------TELKGYTILEAIRFLLSSEDEIMIDAACKVSLPSTLVKTIYLFFDLPAAA----------TTVTVTDLTENATETEDEMLKNNEKLHDMIGQIMEGLCRFKCVSEELVRKDDLLLLFVGTTSQVAEANNCWRKLCARLLEVIADKSITNAVIKYVIVKKCVRIFVKNLSSAPSNSHSDAQKTAESIICLSCFLKNSAYLTDQLLDEFYEADGYTVIKDFLL------KSETDNEIVRNILLMAISLVNSGKFEITPQ---YTSGLVQLPAFQLPIPAGNGLSVRNLNAFALLYHVFLESTSESTSCTVIDILHSIYTCDPANYFILDKEYPLSIFIDQLERKPHAVRVKLLELIEFAVFQLSHIPCRELISLCVLLKTEISAGKTAMCTIIVQMCFKLITVDAIIKDAFREVGLLDALCFIIRRMFEMYEKNIQNASFTVTSTSSRSQDQLKLSLLTTDLLTIIIKNNTENGKLFTECFGAKLLIEIVCEVNEEWRSSLLQLVKQLLIVAPTDQYIMHLVNTLQDRIPIENLEVMFSLLKALLGVVRESHKVRIQFRKSGGFLALSALLLGLEKRFTDL-HPAGDGRIPREQCQMLEFVHIIFKVFTLSMRFEPSNAKYFSTEITWDSITSLLRLTSIF-NESTVISIEETE------WKS---LTHTDLASEIAACHEVFRLDDNIEA----GNVPKGMPF------NIYFGCYVCRLIFNMALDNYEK---------------------MTSDIRW--NDDGASLEESIVSWTSSLLVHPGAIISMLCLLPSISASSMKWT--IAAQYYVSLLLKAILKSERNQQIMCQ-VDMPKHLLRIAEKLFLTENHILLQPFYYLLERLSYQSLTPNQLRSFLRLDSPLCCRSLDDDEDDDDDSKI------------------------------EIADNEGGPVPLQRVKALVSMMTPRDQ---------------------YIGTAPSFVEFDMSVEGFAALYLP--------------------SLAPMFSTTKAERIFPPLNGFSFCTWIYLDALSDKKADAHPIRLLTVTRAVAPPNSDPPSKKPSQTAHLACFQCQ-FSAFDRSLLISTEE---SDQPGADLEKTANFQTDKLIRITLADQVRCGEWFHLAVVFNR-SVLKSSQVSLYLNGRHISTQKLMYVAQNAGGAATQLAQ-TYSVNAVVGTLPALRRPSRLRFRLASIFLAEEPMTAETVRAVVQLQPHYIGNYQTA------STAPLFHEEKIVFSLSAAATQELTLAKIRTMYGKMDAEILSQHLGISPNDHSTPLRVLCNTISHAPGAGRTFGGVIVGYLGMRTFTPRPVPSLLDSIGGFASVYGLIAMAVDSEGLYASLKSLVSAIRSQPRLLATWNNNRSYQILAVLLEDKAKMLNSHIMHMVFNVTGTADTSRE------------HAPTIS---NPSAFEDLLCDLKVW-----------------KGAPSELHKMLLEHFYELITDHQLNNLQVVRKSS---------LLSRILLIIHDEPTMIKNT--DEIIFNLISAIMQPQCDSRSILKIGQSIAATLP---TSESECYEDSHLPFHISEIQKLFIESSDPPPEALHQVYIRNRLLNIIANFLANSNTQV--QQQMCDQLVRTLGFDWLFALMSPGVHSGTIYLALRILLLILNQPSLLARFKEGSANGGWLSEADSVVRNRAAVVLGFSVSAHGGAVGSKIDINPELSNCGGFAALEHLMAAHADKPYPYYAMLSLLVGQPISAL------------------RF---CD----QFNMELVWTHVFGLNST----SSVFEAINSA------------------------------NFCFDAIIPLFAMIRTSIYHQ----SSIHQPWTVTNPSTVVQMITFMYQNSPAFFNIAHTDEFILALFSTLIEDTNAMGVKSEVANRRSQDGGG--SPDAEYF---------------------QAFLAQPNVRIVMDLLKKICCDNLQVNTSKNDTIIDAILD-NISESGNTRKTQIACLTSLLHSVLEHTVGTDLLSSS--ALPPNTQAQNIVQIVANISLLSSRAVDAFWNGLVFGSESMRMLSTLYHLQVIASKKVNKAVNAEPITGCIMRMTLFILSRPI--------DSVPVQLSVLDALSTLVSKRYLFLSSNEAWFFASLTHLIFMLS-----------VTPDVLF--QFQDNSSSSDLDRTSAQVAMCACRVWSDVICAKQALIEETFKKQSVTDINAARALLSHSAGVYWQQFVDSQ-------------LRAIQTGG-SSAQGSAVTAKDIIQQQISSKFNRVA--SGITRFAAKRSMSTTTALPSSGSVAAWKS--TSTDKQVIFMWLRVHVSLIKELVRAQSTRYTEWHAHVRKWCLHDWHQWEAELTRERGIWGPERASKLEKFKLDLTEGPTTRMRRKLIPNRNFYHIYPFRPHLEAPS---------AKAQRAKVAISFDSKPYYETCLRHRRRTLDT 2293          

HSP 3 Score: 158.688 bits (400), Expect = 8.366e-38
Identity = 69/137 (50.36%), Postives = 97/137 (70.80%), Query Frame = 2
Query: 10979 GFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389
            G  + R L+ R+ LTMHTA+ R DN +P+PI+++A SRDHRS+YVGD  GRV+ W   +  GR  ADHW++D   + C  C+ +F+L +R+HHCRNCG +FC+ CS+ E+ I R+ + +PVRVC KCF  +  QQSS
Sbjct: 3221 GAQFVRVLVQRTALTMHTAFNRPDNVHPAPITAIAPSRDHRSLYVGDGIGRVWCWQSAEGGGR--ADHWVQDVTRQRCDDCEHKFTLADRKHHCRNCGQIFCSTCSRFESHITRMNISRPVRVCRKCFQRL--QQSS 3353          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Match: sel-2 (Putative neurobeachin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q19317])

HSP 1 Score: 340.117 bits (871), Expect = 5.371e-93
Identity = 216/625 (34.56%), Postives = 319/625 (51.04%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISII-----NKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAV------------GQIIQADLNGTNSNAVG--SVPSSVLAVEQNKCLIPPLYTRYV-------------------------AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERIL------ITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249
            +++  EIR +  RRYLLQ  A+E+FL      + AF  +   K   K +     + +  ++ +   ++ S +                +  +W+K EISNF YLM+LNT+AGR++NDL QYPVFPWIL +Y S+TLDL+  S FR L KP+GA SE R   F  RY  WDD   + P +HYGTHYS+      +L+R+EPF   F+ L  G FD  DR+ HSIKD+W+   Q +  D+KELIPE FYLP    N++KF+LG + +G  + D++LPPWA+     F+  HR+ALE D VS  LN+WIDLIFGYKQ G  AV A NVF+HL YEG V     + P + +A+   I +FGQ P QL  + HP +  ++ ++       ++ +  M    S++P   L  +    + P    V   +N V            G   ++ L+   SNA G  S+P +  A   +     P+  R++                         A G+ D S R+ + DS    +V +    +GD++  +  +E  L      +TG     V +W+ +      T    AG     G  P  S ++ L GH  +++ L V+A + L+VSG  D
Sbjct: 1749 RWNLQEIRAIFLRRYLLQNTALELFLASRTAIMFAFDSEDAVK---KVVYQLPRVGVGVKYGLPQSRKTSLMTP------RQLFKHSDMCAKWQKREISNFDYLMFLNTVAGRTFNDLSQYPVFPWILTNYTSDTLDLSVASNFRDLSKPIGALSEARRKFFNDRYTSWDD--DQVPAFHYGTHYSTPAFTLNWLLRVEPFASMFINLHDGKFDHPDRITHSIKDSWDRC-QRDSHDVKELIPELFYLPEMFRNSSKFNLGRRADGTPVDDVVLPPWAES-PEHFVLMHRQALESDLVSCQLNQWIDLIFGYKQRGAEAVRATNVFYHLTYEGTVTPKMAETPGQVAAIEQQILSFGQTPSQLLTEAHPPRHSIMSMAPTMFRRHDEDLCMMMKYISNSPVVYLAANTFHQL-PQPTVVGVAQNLVFSLNKWDNSYSYGASQRSALSMDPSNAEGQVSLPLTADAQLASAASTTPVARRHLGDAFDQRLTVQCSNFVTTTDSKFIFACGYPDYSFRIVDTDSG---RVRQAVYGHGDVVTCIARSETSLFSDCYVVTGSMDCTVVLWHWN-----GTTGFIAGEYNQPGEVP--SPRSILTGHEASISALCVSAEHGLVVSGCED 2349          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: bchs (gene:FBgn0043362 transcript:FBtr0079144)

HSP 1 Score: 1158.67 bits (2996), Expect = 0.000e+0
Identity = 567/1068 (53.09%), Postives = 740/1068 (69.29%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVP-----STPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAP---AERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEM-PDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATG---RSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQ--MRPNMRK--------------------LRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCF 11362
            DN+  +  ++   EKI FMFRCAR+QGLD  EGLLLFG+ + YI+DGFTLLK REI +I+ +P   +EPI+P     S+ T    +H+ +   KF++ EIREVHKRRYLLQPIA+EVF  DGRN+LL+FP+K++NK+  +F+ +A++L  NAQ S++GQK+ + +E  +  IFS  +GE SVTQRW +GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE LDLT+P TFR   +PMGAQ+E RL QF+KR++EWDDP GETPPYHYGTHYSSAMIV  YLVR+EPF+Q FLKLQGGHFDLADRMFHSIK+ W SAS+ NMAD+KELIPEFFYLP FL+N N FDLG KQNG  L  ++LPPWAK D REFIR HR ALECDYVS HL+ WIDLIFG KQ G AAV+AVNVFHHLFYEGNVDIY+IDDPLK++A IGFINNFGQIPKQLFKK HP K++    S  +  IDP + +  ++     +RLF+HNLDN++PSLQP+KELK  VGQI+Q D              +V AVEQNK ++PP YT+Y+AWGF+D SLR+G YD+D+   V E      G+I+   C N ++++T G S+VV +W    N                    +L+++ +L+GH +AVTCLA +A+YN++VSGSRD T I+WD+ R  ++RQL GHA  VAA+ I+E+TG +A+C+ T+LH+WSI+G+ LA VNT  G   R +QIL V  S + +WD  NV+ITG TDGVVRMWSLE+ QVPI              VSSQ   ++V     S   ++++ D+  + +  KS+    +   + +S    SI    + S    +        E+  +    S+     ++ ++ A      S+     ++ +  +RP+                       LRKGF WQRQL+FRSKLTMHTAY+R DNA P+ I++L +S+DH+ +YVGD RGR+F WSV ++PGR +ADHW++DE A+ C+ C ++F+L ER+HHCRNCG VFCNKCS+ E+EI RLR+ KPVRVC  C+
Sbjct: 2457 DNETFLR-LLEEQEKISFMFRCARVQGLDTFEGLLLFGKEHCYIVDGFTLLKNREIRDIDTLPPGAYEPIIPNSGGTSSTTSRAVSHKLRQCSKFAYEEIREVHKRRYLLQPIALEVFSEDGRNYLLSFPRKVRNKVNQRFLALATALNDNAQQSVAGQKRTASVEQ-TAGIFSGLIGETSVTQRWVRGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEELDLTNPKTFRDFSRPMGAQAEERLEQFQKRFKEWDDPHGETPPYHYGTHYSSAMIVCSYLVRLEPFSQPFLKLQGGHFDLADRMFHSIKEAWLSASKLNMADVKELIPEFFYLPEFLSNFNNFDLGTKQNGETLNHVILPPWAKHDPREFIRLHRSALECDYVSQHLHLWIDLIFGCKQQGPAAVDAVNVFHHLFYEGNVDIYNIDDPLKKNATIGFINNFGQIPKQLFKKAHPAKKM--GGSRHSALIDPTSLIQGNSTVLQTDRLFFHNLDNLKPSLQPIKELKGPVGQILQPD-------------KTVFAVEQNKVMMPPSYTKYIAWGFADHSLRIGLYDTDRASFVSEASAQNSGEILTCACPNAKMIVTAGTSSVVTIWKFDANRK------------------SLAVKHSLHGHTDAVTCLAASAAYNVIVSGSRDGTAIVWDMTRFTFVRQLRGHAGVVAAVSINELTGDIATCSATWLHVWSINGDALAMVNTCVGSADRMQQILCVAFSQIREWDQQNVIITGSTDGVVRMWSLEHTQVPIDRK-----LKRGTEVSSQDKPDTV-----SLEGKDNKDDKMSLMKQIKSLSQSEEEMEIVKSASESSISEASQHSHGSSKSAEAGPKAEVQGERRKSSISGAKSLHEMKSATVEGQGSSYDPKSNEDEHAIRPSKSDTSLTDGFVVIDNDRHKGDQILRKGFRWQRQLMFRSKLTMHTAYDRKDNAEPASITALTVSKDHKILYVGDARGRIFSWSVTEQPGRGVADHWLKDEGADQCVKCHVKFTLYERKHHCRNCGQVFCNKCSRFESEISRLRILKPVRVCQACY 3479          

HSP 2 Score: 1070.84 bits (2768), Expect = 0.000e+0
Identity = 817/2626 (31.11%), Postives = 1306/2626 (49.73%), Query Frame = 2
Query:  122 SLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS-IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETE-QDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXI--------SNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENS-EGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSD-SSFIPNPMK---LPVPPSSIN----NCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIAT-THPIRLLSLARSLQGSNEF-ISCLNISIINSPNHVILVSTKEEVFGNREQ-ENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYEN-PIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTL--SALGTSETKINL-NENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPA---------------------ALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKL--------IMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPP--GGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKR--QITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIV------GYSTWY-NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXX-----XXXXXXXXXXEQI---CLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSC-LDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELY 7765
            SL  LK LF +Y          + D  LY+++PLF K+F   P  ++ E+F DV  FC  VS LMV EI+KRA+NQ TE AS+AIV++L+   T+    E + GW+LL  L +L+ G   LI+ M  A++PST VKCLY+FFDLP  E +             ++ G    +++     RR +L   F Q+L ++C YP   EEL R +DL LLF A+ S CP HN  WRK AA++L TI+ NGL+ + + +I+ K  ++ C+ N+ +    + +EIV++FVT+F  L++SS V+Q+L+DDFR SQGY  + +FL+K +   S   E Q +IR+L+++I+ L  CG+ ELRP P    +  + ++ F+LP   ++   +RN YAF VLQ+VFL + T  LC  IL+AI  +Y  + ANYFILE + T   F+E++H KS  +QE+  +L++ IV  LN+VP KE+ SLS+++K       + L +K  + ++ HN +FK+V +++GILEI V  L  YA +++K      S  V  E +    L       ++           S N +LFR+ GG+ CV  LV F   + +AL  ++ L LS+G ++DM + L L+ S++   +  KI++L  L   LK+SHR R VFRKV  FV      V L+G  +L    P   I +Q+L+  ++ +   L  A++ EP+N ++F   +S +SL + +R LGCFG    L  +  + E   S     +++F  + LS  +S++    L                              C + + +Y  A++ F+   L               + T+ SD  + + +P K    PV PS +N    +    IVHP  V+ ++ L+PA+  D       ++LQ+Y+ E +  L   +RN QIMC+   +  +LL   + A+  E+HPLH     + ERLA Q + P  +R FLRL +PL C  I +                QP     +KL                    GGP+ LTR+K+L+ +TT +                  D+     + +P FVE++M  EGFGCL+LP        +  ++      I+ N IGGIG G+R+FPP  G ++STW CV+KFS   T  H +RLL+L R++    E  ++CL+I ++++ +  I+VST+E +   R+   ++    S + +A   C  LL E  W +LV+  +R  ++K+SS   +L+G  + T+KL+YI+ + ++   S+ T  T ++ YIGT P   + S LCW+QG  H IE+ LT   V  I +LGP+Y+G+ Q P L  ++  +  LV E++V+  L A  +S  TL +I K+Y+  D   IA+QL+++  E ++PI+I+HN+AGHL+GAGRSLG +++GY G+R FSP P++ +ID VGG  VLLGI+AMA D E+LYA VK +   +  NR+   E++    Y+ +    KKK+HLL+S I  L  GL G+ +   QD               ++   N   F +++CDL +W +  N    +       L   S            SD  +           +K + DL L+ +++ ++ Q      +    E L  L+E ++    +  DL  FGQ++   L  +  G  E  + L +  N ++ +       IYL   RN C    L          T    I +++ K LG DW+LLFMQP VH +TV++A+R LV + +   ++++FRD     G+L  T++V Q++   L       +P                         E+   + ++PGF  L+ L+ HH  +P++YF++ AL++G  +K +                            ++F+ + V +FL+G       ++N Q              L +++                 +C E   +LL M+R +++    EC      W+  +P T+++    LY +  +F  V M  D +  L   ++P     + S P       P S   T  +  G+      +  +   E+L+  P  KL        I+DF ++I+VD   L  +     VID++L+   E+       Q+QT  + +L +H +A D+L G+   LPL P        I  N++Y  +R+VDK+WQ     +P  I  ++ +LI Q ++R   ++ E L+ S NR ILF LSR   + +  ++ +      + +     +G+G     N + EF+ CL + L+QL   + I+        +TW+ NP + + +   ++ NQ++   L   I   A  +W+E+   KK  +EE FK+ L+     S    +    EQ+     K W +Y+E+E   T  + W                          L  QI  K+ +++    L RL           S + +      R  + ++ E A      H+ ++K+L+D     + +       Y+   W   E EL RERGLWGP  GSC LDKW+LD+ EGP RMRKK + N+ FY HYPYRP      DN +         K+KVA+S D + Y
Sbjct:   61 SLTTLKKLFNEYTHPREPLSEQERDDKLYEMLPLFCKVFSSCPSNDMSEKFWDVVAFCQQVSRLMVSEIRKRASNQSTEAASIAIVKFLEVETTE----ETSSGWMLLATLNLLANGDVSLIQVMTAAAVPSTLVKCLYLFFDLPIVEDD-----------EPSADGGAVSEFNAH--ERRTLLQKVFVQLLVKLCSYPYPAEELARMDDLTLLFSAITSPCPIHNIVWRKNAAEILTTISRNGLTDAVVSYIHSKGCMALCVDNMQRLTFGNPLEIVEMFVTVFCFLKDSSQVSQILMDDFRASQGYVFLSDFLLKFDNNRSQSLEIQAAIRNLVLMISSLCMCGFYELRP-PASQFNTAFKLQNFQLPQATSRETCVRNVYAFQVLQNVFLKSTTPALCCTILDAISRVYHSENANYFILESEQTLSSFAERIHMKSPQIQEKFYDLLEFIVFQLNFVPCKELISLSLLLKHNQSTSCSILCLKTLLNILRHNAVFKDVYREVGILEIFVGCLTRYAAHVQKITKGDESVVVELENESEEELFDTLGKHVLEALTMLLGGGASNNAQLFREYGGAKCVHELVKFKHCRPQALGIVRELILSAGGDDDMLHILSLMHSVSPLQVEFKIQILNMLLGCLKDSHRTRTVFRKVGGFVYVTSVFVSLDGSMAL----PQPDIPQQDLILLLQIVFQTLATAMRFEPANAKFFHQEISSSSLCDTLRLLGCFGGSSALQDYTGTYEPQQSLLKYYHEIFSGDILSVSFSEDVPYPLS---------------------------YVCIVFRLLYSIALDNFEAPNLSG-------------IITLFSDPPTTLRSPSKELAPPVHPSQLNLTQPSPEPRIVHPGVVLCMLQLLPAVEYDMAPL-QAVQLQVYLSEIIKSLVRSERNQQIMCDH-GLAEKLLKLTRRALAEESHPLHVPMQYILERLAAQALQPTELRQFLRLGEPLSCADIDLQ---------------QP-----YKL--------------------GGPVPLTRIKTLVSMTTPR------------------DFRAHGSSTLPPFVELDMSAEGFGCLYLP------SLAPQATATAGGTIDANSIGGIGAGDRIFPPQTGLTYSTWFCVEKFSDPKTDPHCVRLLTLVRTIHNPREENLACLSI-LLSARDKAIVVSTQETLVTPRKSIGDWEPEGSDDGIARIWCPDLLHEGQWHNLVVVLNR-AVLKNSSLFLYLDGVPMHTQKLHYIAQHPAAGNASL-TSPTQIFGYIGTPPIWRRYSRLCWKQGVCHLIEDVLTQQTVQTIYQLGPHYMGSLQAPQLGKQSESLAPLVPEDRVLLGLNAKAVSKLTLVKIRKVYSRADNKSIAKQLNMNSHENATPIKILHNSAGHLAGAGRSLGGVVVGYLGVRVFSPHPVSAMIDTVGGCNVLLGIIAMAQDVESLYAGVKALTCVVRSNRAAQAEMDRKRCYQTLGMFFKKKKHLLNSHILHLTFGLVGTVNSG-QD---------------MSAIPNVTAFQDLLCDLEIWHNAPNGLLRSLLEHLLELVVES------------SDKKQN----------VKIMRDLQLLVKLLHIITQIQ----DHSTREILFSLLETLLGGQPRHTDLLLFGQYVAAKLPHAHSGGLERAVLLPSMKNPAEDQDGGVAQNIYL---RNRCL--SLLHGLLFTPRNTVNYVICDDISKTLGMDWLLLFMQPHVHFTTVIIAVRILVVICANESFLVRFRDATHNGGYLRFTEMVSQRKMLGLGAQQLNQRPTNGTGTVIVATPQNTIQHLPTQIAGEVRAAALNIPGFQLLEWLMNHHLDVPELYFLITALIMGQPVKVL------------------------ATEHTKFDLDRVWSFLWGAPV----SANTQ--------------LPKLN-----------------ICPEGVCVLLAMVRGIVHG--GECA----PWLHSHPETIIQLLFSLYQNLTDFAPVMMTGDVVTSLVAVLFP-----LASRPADSE---PNSGASTPTDDTGS------SFALPPPETLHGAPQPKLTAHPVCNCIIDFLRVIVVDSLGLNMQGKPTPVIDLVLDAAPESAELPLQVQYQTQIIIALMDHLLAADVLVGEQAALPLVPLLQSQMQYIAPNVFYLTARIVDKLWQGCLARNPHDIFDFVIKLIVQAKRRSSSLSLEHLHHSLNRSILFLLSRPTDDSRADQMSVLEALHKIIQHRLLIFGAG-----NHELEFIGCLTYCLLQLTADMKIILEPATSRNTTWHVNPQTETAEPKDEDLNQLQGRNL---IVGAAFRVWEELYVCKKPAIEEVFKVSLTSPPPNSKAPDLQTTREQVMELASKLWFNYVEAERKATYRAPW-------------------------ELHTQIQSKIQKVTGG--LSRL----------TSRTKTKKEELVRTRSTLTREAAYESTGIHVQLIKDLLDLRAKQYQQMLQHTQRYVYQDWVQSEMELTRERGLWGP-TGSCSLDKWILDTTEGPHRMRKKTMRNDVFYLHYPYRP-ELELADNRQ--------LKYKVASSLDSKTY 2374          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: rg (gene:FBgn0266098 transcript:FBtr0344651)

HSP 1 Score: 382.104 bits (980), Expect = 2.174e-105
Identity = 226/637 (35.48%), Postives = 344/637 (54.00%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERL-----FYHN--LDNMEPSLQPVKELKNAV-----------------------------------GQIIQAD----LNGTNSNA-------VGSVPSSVLAVEQNKCLIPPLYTRY-VAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249
            K+ F E+R +  RRYLLQ +A+E+FL    + L AFP +   K   K I+    + +  ++ I   ++ S +           M   ++TQ+W++ EISNF+YLM+LNT+AGR+YNDL QYP+FPW+L +YES+ LDL+ PS +R L KP+GA + +R   FE+RY  WD  S   PP+HYGTHYS+A     +LVR+EPFT  FL LQGG FD  DR+F S+  +W++  Q + +D+KELIPE+++LP    N++ + LG++++G ++ DI LPPWAK    EF+R +R ALE ++VS  L++WIDLIFGYKQ G  A+ A NVF++L YEG+VD+  + DP+ R AV   I NFGQ P QL  +PHP +   + +S          P+  SA  E L     FY N  + ++  +  P   L + V                                    Q +  D    ++GTN+N+       +G   S +L +  N C +  + +R+ +A GF D S RV   ++ K++++      +G    V C+        ++  + +G     V +W+ +         G   +            +A L GH +AVT + ++A   L+VSGS +
Sbjct: 2705 KWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVK---KVIKALPRVGVGIKYGIPQTRRASMMSP------RQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWD--SDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNC-QRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKS-PEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHLS----------PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSN-CFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIV-----FGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGEGDVPTP-----------RATLTGHEQAVTSVVISAELGLVVSGSSN 3301          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: rg (gene:FBgn0266098 transcript:FBtr0344649)

HSP 1 Score: 381.719 bits (979), Expect = 2.482e-105
Identity = 226/637 (35.48%), Postives = 344/637 (54.00%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERL-----FYHN--LDNMEPSLQPVKELKNAV-----------------------------------GQIIQAD----LNGTNSNA-------VGSVPSSVLAVEQNKCLIPPLYTRY-VAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249
            K+ F E+R +  RRYLLQ +A+E+FL    + L AFP +   K   K I+    + +  ++ I   ++ S +           M   ++TQ+W++ EISNF+YLM+LNT+AGR+YNDL QYP+FPW+L +YES+ LDL+ PS +R L KP+GA + +R   FE+RY  WD  S   PP+HYGTHYS+A     +LVR+EPFT  FL LQGG FD  DR+F S+  +W++  Q + +D+KELIPE+++LP    N++ + LG++++G ++ DI LPPWAK    EF+R +R ALE ++VS  L++WIDLIFGYKQ G  A+ A NVF++L YEG+VD+  + DP+ R AV   I NFGQ P QL  +PHP +   + +S          P+  SA  E L     FY N  + ++  +  P   L + V                                    Q +  D    ++GTN+N+       +G   S +L +  N C +  + +R+ +A GF D S RV   ++ K++++      +G    V C+        ++  + +G     V +W+ +         G   +            +A L GH +AVT + ++A   L+VSGS +
Sbjct: 2725 KWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVK---KVIKALPRVGVGIKYGIPQTRRASMMSP------RQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWD--SDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNC-QRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKS-PEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHLS----------PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSN-CFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIV-----FGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGEGDVPTP-----------RATLTGHEQAVTSVVISAELGLVVSGSSN 3321          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: rg (gene:FBgn0266098 transcript:FBtr0344668)

HSP 1 Score: 381.719 bits (979), Expect = 2.622e-105
Identity = 226/637 (35.48%), Postives = 344/637 (54.00%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERL-----FYHN--LDNMEPSLQPVKELKNAV-----------------------------------GQIIQAD----LNGTNSNA-------VGSVPSSVLAVEQNKCLIPPLYTRY-VAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249
            K+ F E+R +  RRYLLQ +A+E+FL    + L AFP +   K   K I+    + +  ++ I   ++ S +           M   ++TQ+W++ EISNF+YLM+LNT+AGR+YNDL QYP+FPW+L +YES+ LDL+ PS +R L KP+GA + +R   FE+RY  WD  S   PP+HYGTHYS+A     +LVR+EPFT  FL LQGG FD  DR+F S+  +W++  Q + +D+KELIPE+++LP    N++ + LG++++G ++ DI LPPWAK    EF+R +R ALE ++VS  L++WIDLIFGYKQ G  A+ A NVF++L YEG+VD+  + DP+ R AV   I NFGQ P QL  +PHP +   + +S          P+  SA  E L     FY N  + ++  +  P   L + V                                    Q +  D    ++GTN+N+       +G   S +L +  N C +  + +R+ +A GF D S RV   ++ K++++      +G    V C+        ++  + +G     V +W+ +         G   +            +A L GH +AVT + ++A   L+VSGS +
Sbjct: 2498 KWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVK---KVIKALPRVGVGIKYGIPQTRRASMMSP------RQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWD--SDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNC-QRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKS-PEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHLS----------PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSN-CFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIV-----FGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGEGDVPTP-----------RATLTGHEQAVTSVVISAELGLVVSGSSN 3094          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Match: rg (gene:FBgn0266098 transcript:FBtr0344648)

HSP 1 Score: 381.719 bits (979), Expect = 2.695e-105
Identity = 226/637 (35.48%), Postives = 344/637 (54.00%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERL-----FYHN--LDNMEPSLQPVKELKNAV-----------------------------------GQIIQAD----LNGTNSNA-------VGSVPSSVLAVEQNKCLIPPLYTRY-VAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRD 10249
            K+ F E+R +  RRYLLQ +A+E+FL    + L AFP +   K   K I+    + +  ++ I   ++ S +           M   ++TQ+W++ EISNF+YLM+LNT+AGR+YNDL QYP+FPW+L +YES+ LDL+ PS +R L KP+GA + +R   FE+RY  WD  S   PP+HYGTHYS+A     +LVR+EPFT  FL LQGG FD  DR+F S+  +W++  Q + +D+KELIPE+++LP    N++ + LG++++G ++ DI LPPWAK    EF+R +R ALE ++VS  L++WIDLIFGYKQ G  A+ A NVF++L YEG+VD+  + DP+ R AV   I NFGQ P QL  +PHP +   + +S          P+  SA  E L     FY N  + ++  +  P   L + V                                    Q +  D    ++GTN+N+       +G   S +L +  N C +  + +R+ +A GF D S RV   ++ K++++      +G    V C+        ++  + +G     V +W+ +         G   +            +A L GH +AVT + ++A   L+VSGS +
Sbjct: 2462 KWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVK---KVIKALPRVGVGIKYGIPQTRRASMMSP------RQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWD--SDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNC-QRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKS-PEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVLDPVMREAVENQIRNFGQTPSQLLMEPHPPRSSAMHLS----------PMMFSAMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSN-CFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIV-----FGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGEGDVPTP-----------RATLTGHEQAVTSVVISAELGLVVSGSSN 3058          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-070705-153])

HSP 1 Score: 1198.73 bits (3100), Expect = 0.000e+0
Identity = 849/2671 (31.79%), Postives = 1359/2671 (50.88%), Query Frame = 2
Query:   26 KSNLEMNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKG-GLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKT-----CNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLK--KEQDAGISDSVNN---EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPP---WDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXX-------------XXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQ-----------MQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEV---FGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYEN---------PIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIYLIEIRNMCFXXXXXXXXXXXXXE--TNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQ--NLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY 7768
            K  L+MN V+RI+    +   +     +D    L  L+ LF++      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE+    Q +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP HN  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + +I+LE+   +E+ +D+++ L+ L+  LTT G  EL+P   L+    + + GF +P P  K  ++RN  AF+VLQ+ FL A++  L   ILEAI  IY  D ANYFILE Q+T   F+E++ K    VQ +   L++ +V  LNYVP KE+ S+SV++K+     C++  T +LL     +L  H+ +F +V +++G+LE+ VN LH YA  LK   +  +   DS NN   EQ +L  L+++ LT+L+   + N  LFR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S  +  L LK  +L +L  VL+ESHR R VFRKV  FV     L+ +E     +  PP   W+ + + ++ E +  I   LT A++ EP+N  +F   + Y  L +A+R LGCF SD   +        N+Q +       +E                  D I    N    L  CS+          +  +MY  A + FD+R                             Y  +  S S      +KL +  SS ++   +++HP AV++++ L+P++  D  Q  H ++LQ+ +   L  L   +RN QI+CE+  +   LL     A+ +E+HPLH     +FERLA+Q + P  +R+FLRL +PL C            +   S+  Y+        L   G G D    I++           ++   G  + LTRVK L+ +TT                    D      +  P+FVE++   EGFGCLFLP  +    ++  S+       +  ++ G+G GER FPP  G S+STW CV++FS+   +HP+RLL++ R    S +   CL I ++++ +  ++VSTKEE+   + +   E  S        A F C  L+ E  W HL+L   + GM+K+S  + +++GQ++ T KL+Y+  +   S  +   ++++VY+YIGT P   ++S L WR GP HF+EE L A+ V+ I  LGPNY+G+FQ   L  ++         P+G LV EEKV FSL+A+++S  T+ +I K+YN+LD   IA+QL +   E ++P++++HNA GHL+G+ R++GA +IGY G+R F   P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL L L ++ +         P  T I   LS L++    + N   DL RFGQF+  TL      E  + +   N+  ++     EF   +    I      + + +       E  T   +  EEL++ LGFDW+L+FM+  +H STV  A+  LV LLS    + +F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQ+LLP H  +P+IYFML+AL     I  +P++L                         QF+ +S+  F+FG                  +A  +G L N                    MC+E A +LL M+R MLN        E  +W+R+YPITL++FF YLYH+  +   +    DFL  L   ++P +           D    S  ++   F  ++ +  +++E C     N+ N   +T     + PA+K + DF +++I+D   + P +    +ID++LE   E +T+   K+FQ+  ++S+ E  +A D+L G+  +LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  +++ ++ +LI+Q ++R   ++ +S+Y   NR IL++LSR        K + + +  L      T   + +  P N D EFV CL H LI L  G ++ G+        +TW+   ++ ++N  D+       +  + +      +W E+  +K+Q+LE+ FK+      +   ++ +  P +E+   K+W +++  E                         I+ G  V+ + Q     KL+R+S    L +L+ S      SG              N++S +E   W+  HI+VV++L+        +++   + Y+  +W  +E EL RERGLWGP +GS LDK+ LD  EGPCRMRKKM+ N+ FY HYPY P       + E +    +  +++ A S D + YY
Sbjct:   16 KKPLKMNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFSELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSTMNEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEVNQSE----ETSRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHMPEVPAATQTELP------------------LADRRALLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPHNLPWRKSAGEVLTTISRHGLSVNVVKYIHEKECLSTCIQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRMCQGYTFLIDLMIRLEQAKEDES-KDALKDLVNLVTALTTYGVSELKPA-GLTTGAPFLLPGFVVPQPSGKGHTVRNIQAFSVLQNAFLKAKSGRLARMILEAIANIYAADYANYFILEAQHTLSQFAERVTKLP-EVQSKYFELLEFVVFGLNYVPCKELFSVSVLLKSSTSYGCSITATRTLL-----KLGRHHPVFSDVFREVGLLEVLVNLLHKYAALLKDPTQTHSDQGDSKNNVAEEQKQLAWLVMETLTVLLQGSNTNAGLFREFGGARCVHNIVKYRQCREHALMIIQQLVLSPSGDDDMGTLLGLMHSAPTAELQLKTDILRALLAVLRESHRTRTVFRKVGGFVYVTSLLLAMERS---LCSPPVIGWEKVNQNKVFELLHTIFCTLTAAMRYEPANSHFFRTEIQYEKLADAVRLLGCF-SDAKKVGPATVFPSNAQPFQR----LLE------------------DEIIPAENVCPTLKHCSK----------LFIYMYKMATDSFDSRAEQVPPCLTHETSLPSPWGTPAITRKRHGYSSSSNSASGKALTDLKLHLGNSSQHSSDPVVIHPGAVLAMLDLLPSVSSD-TQPEHALDLQLAVANILQLLVHSERNQQILCEA-GLHSRLLQRCSCALGDEDHPLHPPLQRMFERLASQALEPMVLREFLRLGNPLNCGAWDKKLLKQYRVHKPSSLSYEAEMRNSMTLSMEGFGPDSVFTINEDNSQYRISRSLVRSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVELDTSLEGFGCLFLP--SLAPHNAPSSNANTSGVSDGAVVSGMGNGERFFPPPSGLSYSTWFCVERFSTPPQSHPVRLLTVVRRATSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQSYVDDFSEESSFYEILPCCARFRCADLITEGQWHHLLLVMSK-GMLKNSMATLYIDGQMVSTVKLHYVHNSPGGSASANPPVVSTVYSYIGTPPAQRQLSTLVWRLGPTHFLEEVLPAASVAAIYELGPNYVGSFQAVYLPCKDSKTEAVPPCPVG-LVPEEKVSFSLFAHSVSALTVAKIRKVYNKLDSKAIAKQLGVSSHESATPVKLVHNAVGHLNGSARTVGAAVIGYLGVRAFVTKPVATNLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRPLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLLREFQLIPKLL-LTLRDQSLS-------QPTITAIGNVLSLLLQ---GFPNT-YDLLRFGQFISSTLPTFAVCEKFVIMENTNEEKIDRGADEEFGGLLSSNLILLRNRLLDILLKQLFSCKEKGTVNAQACEELVRTLGFDWLLMFMEEHIHSSTVTAALLILVVLLSNQSILSRFKEGLSGGGWLDHTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFPVLQTLLPKHTNVPEIYFMLMALFFQQPITELPESL-------------------------QFDLDSIWTFIFGVPAS--------------SATVVGSLHN--------------------MCTETAFLLLAMLRSMLNLPWQ--SEEEGSWLREYPITLMQFFRYLYHNIPDLAPMWHSPDFLCTLAATVFPFNIRPYSEMVSDLDDEASSPTEEFKAFVTDTGMNRSQSEYC-----NVGNKTYLT-----NHPAKKYVFDFMRLLIMDNLCMTPASKQTPIIDLLLEASPERSTRTQQKEFQSYILDSVMEQLLAADVLMGEEASLPITTGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLVVDFIVQLITQSKRRSQGLSLDSVYHCLNRTILYQLSR------PHKTVPQQVTLLDSLRVLTVNRNLVLGPGNHDQEFVACLAHCLINLHTGSSVEGFGLEAEARMTTWHV--AVPSENESDSVQSQDVSEGRQLLLKAVNRVWTELMHSKRQMLEDIFKVSLPVNDRGHVDIGTARPALEEPAAKSWQNHLVHEK----------------------KCISRGETVAPANQS----KLSRVSSGFGLSKLTGSRRSKKESGMNK-----------NNLSAQETFQWMFTHIAVVRDLVAMQYKEHQERQQNALKYVMDEWAGIEYELLRERGLWGPPIGSHLDKFQLDMTEGPCRMRKKMVRNDMFYIHYPYVP-------DPEPNASTQKPARYRRAISYDSKEYY 2427          

HSP 2 Score: 986.482 bits (2549), Expect = 0.000e+0
Identity = 459/769 (59.69%), Postives = 587/769 (76.33%), Query Frame = 2
Query: 8255 QWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVP 10561
            Q  +   +  ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P     +    +R  S  F++ +IREVHKRRYLLQP+A EVF GDGRN+LLAF K ++NK+Y +F+ V  SL  ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDL +P TFR L KPMGAQ+++RL Q++KR+++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG+KQNG  LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G  AVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+    S  N +  P  P+  ++  +++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK L+PP + +  AWG++D S R+ NY+SDK + VYE    +G I+C +C N +++ITGGFST + VW           +GS+  +     A +L+L+  L GH +AVTCL  +++Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  +AS NT TGRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP
Sbjct: 2504 QKTDNTTLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTVTREIRDIETLPPNMHEPIIPRGARQSKSQLKRTCS-IFAYEDIREVHKRRYLLQPMAAEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLA-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLNNPKTFRNLSKPMGAQTDDRLIQYKKRFKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGSKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---SKSNGEA-PGGPVTLNSTLDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLVPPAWNKTFAWGYADLSCRLSNYESDKAVVVYECLSEWGQILCAICPNPKLVITGGFSTAICVWE----------TGSSKEK-----AKSLTLKQALLGHTDAVTCLTASSAYHIVVSGSRDRTCIIWDLNKLSFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGSPVASANTFTGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRIEFLQVP 3237          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: wdfy4 (WDFY family member 4 [Source:ZFIN;Acc:ZDB-GENE-090313-322])

HSP 1 Score: 625.55 bits (1612), Expect = 0.000e+0
Identity = 321/709 (45.28%), Postives = 448/709 (63.19%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQN---SKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPH----PTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELK-NAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPI-STSFCSADFSEPQAVSSQP 10621
            ++S+ +I+E +  R+LL+  A+E+FL +G +  L F        Y +   V SSL    +  ++  +      K    ++++      EK+V  +W++GEISNF+YLM+LNTLAGR+YNDLMQYP+FPW++ADYESETLDL+SP+TFR L KPMGAQ+E R  +F +RY E ++  G+ +   HY THYSSA+IVA YLVRMEPF+Q FL+LQGG FD+ +RMFHSI++ WESAS+ NM+D++ELIPEFFYLP+FL N+N+FD G  Q+G  L D++LPPWAKGD +EFIR HREALE DYVS+ L+ WIDLIFGY+Q G  AVEA+N FH  FY    D  S+ DP+ +S ++G+INNFGQ+PKQ+F KPH    P K      + ++ QI P             F+  LD ++PS Q VKE+    VGQI+  +               VL VE+NK LIPP    Y  WG  D +   G+Y  +K   V E    +G+ +C  C N   +IT G STVV VW++ ++  K                  + L+  LYGH + VTCL  + ++++++SGS D+TCI+WDL  + Y+ QL  H++ V+A+ I+++TG + SCAGT+L+LW++ G+ LAS+NT       IL    +   +WDP NV+ITG  DGVVR+W  EY +V +     CS   S+   +SS P
Sbjct:   12 RWSYDDIKEANFMRFLLEDNALEIFLKNGTSVFLVFFNNDHVNAYKRLCSVVSSLKGRGETVLNVSRSGLLFVKTRRKTSAV------EKTVLIKWQRGEISNFEYLMHLNTLAGRTYNDLMQYPIFPWVIADYESETLDLSSPATFRDLSKPMGAQTEKRKEKFIQRYLEVENNDGDLSAQCHYCTHYSSAIIVASYLVRMEPFSQTFLQLQGGTFDVPERMFHSIQNEWESASKDNMSDVRELIPEFFYLPDFLVNSNQFDFGCMQDGTPLNDVVLPPWAKGDPQEFIRVHREALESDYVSSRLHLWIDLIFGYRQQGMPAVEALNTFHPYFYTDKHDRASMKDPVMKSTMLGYINNFGQMPKQIFTKPHASRTPNKSTAGKETSVSSQITP-------------FFFKLDKLKPSAQAVKEVSLGPVGQIVCKE-------------KDVLVVEKNKLLIPPQLNTYFCWGSYDQTCSFGSYTGEKSFGVCESLSDWGEPVCAACPNNSTIITAGTSTVVCVWDVFISKDK---------------LKHMRLKQTLYGHTDTVTCLVASEAHSMIISGSLDQTCILWDLEDLSYITQLPEHSSAVSALAINDLTGEIVSCAGTHLYLWTMKGQLLASINTYYEPEGNILCCCFTQKHEWDPRNVIITGSADGVVRIWKTEYTRVQLPGHEECSV--SQGHVLSSAP 671          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1])

HSP 1 Score: 424.476 bits (1090), Expect = 2.024e-118
Identity = 272/794 (34.26%), Postives = 403/794 (50.76%), Query Frame = 2
Query: 8291 GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK--RLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQP-VKELK--NAVGQ-------IIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASC-----AGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
             + E I F  RC  +       G LL G+S  Y ++              N+P + H+   P   T          S  +++ EI+EVHKR + L+  A+E+FL +GR  LLAF   K ++ +Y               H+I      + +E G+ S         ++T  W  G+I+NF+YL +LN  AGRS+NDLMQYPVFP+IL DY +ETLDL   S +R L KP+  QS+ +  ++   YR            DDP     PYHYG+HYS++  V  +LVR+ PFT+ FL  Q   FD+ DR FHS+  TW  +S  +M D+KELIPEFFYLP FL N   FD G +QN   +  + LPPWA+ D R FI  HR+ALE D VS  L +WIDL+FG KQ G AAV+A+NVFH   Y G +D+ +++DP++R A+   I  +GQ P+QLF   H ++    L+  + +   +  +  LA     E+      D+  PS  P +K LK    VG        +  +  +G    ++ ++P+  +     K  +  +Y++                 ++WG++D  LR+ +  S+  I   +    +    C    +   L TG    V+  ++     + PT                +  Q +LYGH   VT L V   Y++L+S SRD TCI+WDL R+CY++ LSGH +PV A+  SE TG +A+       G+ L LW+I+G+ +  V+      + I +V  S   +    NV+  G  +GVVR+WS
Sbjct: 1874 ATSEPIRFTRRCVSVAPSRETAGELLLGKSGMYFVE-------------ENVP-ETHDNQSPHGET-------EPASFSWTYEEIKEVHKRWWQLRDNAMEIFLTNGRTLLLAFDNTKFRDDVY---------------HNILTSDLPNLLEYGNIS---------ALTHLWSSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILKDYTNETLDLQEASIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGKREDDPMPPVQPYHYGSHYSNSGTVLHFLVRLPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFSASHISRAGTKLLSEAELPAAMGLLVQLAFRESREQ----PRDSGYPSPLPWIKGLKWGEYVGSPSAPDPVVCFSQPHGERFGSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYTDNMLRLKSKQSEPPINFIQCSPLHQVSSCAWVPDSCQLFTGSKCGVITAYSNRFTTTMPTEM-------------EVESQVDLYGHTAEVTGLFVCKPYSILISVSRDGTCILWDLNRLCYVQSLSGHKSPVNAVSASETTGDIATVCDSVGGGSDLRLWTINGDLIGHVHC----REIICSVAFSNQPEGVSVNVIAGGLENGVVRLWS 2600          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1])

HSP 1 Score: 424.476 bits (1090), Expect = 2.321e-118
Identity = 272/794 (34.26%), Postives = 403/794 (50.76%), Query Frame = 2
Query: 8291 GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK--RLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQP-VKELK--NAVGQ-------IIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASC-----AGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
             + E I F  RC  +       G LL G+S  Y ++              N+P + H+   P   T          S  +++ EI+EVHKR + L+  A+E+FL +GR  LLAF   K ++ +Y               H+I      + +E G+ S         ++T  W  G+I+NF+YL +LN  AGRS+NDLMQYPVFP+IL DY +ETLDL   S +R L KP+  QS+ +  ++   YR            DDP     PYHYG+HYS++  V  +LVR+ PFT+ FL  Q   FD+ DR FHS+  TW  +S  +M D+KELIPEFFYLP FL N   FD G +QN   +  + LPPWA+ D R FI  HR+ALE D VS  L +WIDL+FG KQ G AAV+A+NVFH   Y G +D+ +++DP++R A+   I  +GQ P+QLF   H ++    L+  + +   +  +  LA     E+      D+  PS  P +K LK    VG        +  +  +G    ++ ++P+  +     K  +  +Y++                 ++WG++D  LR+ +  S+  I   +    +    C    +   L TG    V+  ++     + PT                +  Q +LYGH   VT L V   Y++L+S SRD TCI+WDL R+CY++ LSGH +PV A+  SE TG +A+       G+ L LW+I+G+ +  V+      + I +V  S   +    NV+  G  +GVVR+WS
Sbjct: 1868 ATSEPIRFTRRCVSVAPSRETAGELLLGKSGMYFVE-------------ENVP-ETHDNQSPHGET-------EPASFSWTYEEIKEVHKRWWQLRDNAMEIFLTNGRTLLLAFDNTKFRDDVY---------------HNILTSDLPNLLEYGNIS---------ALTHLWSSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILKDYTNETLDLQEASIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGKREDDPMPPVQPYHYGSHYSNSGTVLHFLVRLPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFILIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFSASHISRAGTKLLSEAELPAAMGLLVQLAFRESREQ----PRDSGYPSPLPWIKGLKWGEYVGSPSAPDPVVCFSQPHGERFGSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYTDNMLRLKSKQSEPPINFIQCSPLHQVSSCAWVPDSCQLFTGSKCGVITAYSNRFTTTMPTEM-------------EVESQVDLYGHTAEVTGLFVCKPYSILISVSRDGTCILWDLNRLCYVQSLSGHKSPVNAVSASETTGDIATVCDSVGGGSDLRLWTINGDLIGHVHC----REIICSVAFSNQPEGVSVNVIAGGLENGVVRLWS 2594          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Match: nbeab (neurobeachin b [Source:ZFIN;Acc:ZDB-GENE-120329-2])

HSP 1 Score: 366.311 bits (939), Expect = 7.710e-105
Identity = 248/731 (33.93%), Postives = 364/731 (49.79%), Query Frame = 2
Query: 8516 MSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSI-DDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLI------------------------------PISIINKQIDP--MAPLASSAPAERLF----YHNLDNMEP----SLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMS----VNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSGHAAPVAA--ICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMW 10537
            +  K+ F EIR V  RR+LLQ  A+E+F+ +  + +  FP +   K      +V  SL      +  G  Q  +I   S           ++TQRW++ EISNF+YLM+LNT+AGR+YNDL QYPVFPW+L ++ESE LDLT PS FR L KP+GA +  R   +  RY  WD+   ETPP HY THYS+A     +LVR+EPFT  FL   G  FD  +R F SI  +W    Q + AD+KELIPEF+YLP    N+N + LG++ +GV + D+ LP WAK    +F+R +R ALE ++VS  L++WIDLIFGYKQ G  A  A+NVFHHL YEG+V++ S+  DP  R A    I + GQ P QL  +PHP +   +                              P++ +     P    P   +    RLF    +HN   +      SL+    L   +  +I A+ +GTN   +  +    + +   +C +     RY+   GF D S RV + D+ KL ++      +G    V CL         +  +++G     + +W  S    +    P  S     R            A L GH   V C++V A   +++SG+++  C++  + G +  LR L G  + V    IC+S     +          +SI+G+ LA +        +I   T + ++  D G  ++TGG +GVV +W
Sbjct:  337 LHGKWMFSEIRAVFTRRFLLQNTALEIFMANRTSVMFNFPDQPTVK------KVVYSLPCVGVGTSYGLPQARRISLASPR---QLFKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNFESEELDLTVPSNFRDLSKPIGALNPKRAVFYADRYESWDE---ETPPCHYTTHYSTANSTLHWLVRIEPFTTFFLNANGNKFDHPNRTFSSIARSWRHC-QRDTADVKELIPEFYYLPEMFVNSNGYCLGDRDDGVPVCDVELPAWAK-KPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAARALNVFHHLTYEGSVNLDSLASDPPLREATEAQIQSVGQSPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTLPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLEQAHHLPIEMDSLI-ANNSGTNKRQITDLVDQSIQI-NTQCFVVTADNRYILVCGFWDKSFRVYSSDTGKLTQIV-----FGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNNSDYPAPR------------AVLTGHDFEVVCVSVCAELGIIISGAKEGPCLVHTITGDL--LRALEGPDSCVLPRLICVSSEGHCIIYFDRGQFCSFSINGKLLAQM--------EINDSTRAIVLSSD-GQNLVTGGDNGVVEVW 1023          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:100496744])

HSP 1 Score: 2425.59 bits (6285), Expect = 0.000e+0
Identity = 1469/3872 (37.94%), Postives = 2167/3872 (55.97%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLE-SAEFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQP-GFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F ++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL V+ +L+      ++CM T S+PST +KCLY+FFDLP+ P+I    + +                  P    RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+   NE+ +D+++  + LI  LTT G  EL+P   L+    + + GF +P P  K  S+RN  AF+VLQ+ FL A+T +L   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+      +    K  ++ I H+ IFK+V K++G+LE+ VN LH YA  LK       EQ    ++    EQ +L L++++ LT+L+   + N  +FR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L IVL+ESHR R VFRKV  FV     LV +E   S   +  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +AIR LGCF           S  +   N   S+NQ F+   L  D +  + V                 +L  CS+          +  ++Y  A + FD                 H    + + S   P   + MKL    S+++   ++I+HP A++S++ L+ ++  D +Q  H ++LQ+ I   L  L   +RN Q+MCE+  +   LL+    A+ NE+HPLH     +FERLA+Q + P  +R+FLRL DPL C                S+  Y+P   +   +   G G D  FC       R N        G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLPS+AP +  +  +    +         G G   R+FPP  G ++STW C++  SS    HP+RLL+L R    S +   CLNI ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL+ T KL+Y+      S  +   ++++VYAYIGT P   ++S L WR GP HF+EE LTA+ V  I  LGPNY+G+FQ    P  D ++  GSL     V EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HN+AGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ L KKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R         D  L+ +++  +   +++ P    I+  LS L++   S     +DL RFGQF+  TL      E  + +  NN+  LE   +F   +   LI +RN    ++LK+L  S    T   +  EEL+K LGFDW ++FM+  +H +TV  AMR LV LLS P  +L+F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQSLLP H  +P +YF+L+ L L   +  +P+NL+ + P            IS  +N+S QF+ +S+  F+FG            +SG+ +++                            +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +   + +  +FL  L  +++P +           D  + S  ++   F+ +S +  +++E C           M T   L + PA+K + DF ++++++   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GG+Y  + NN++YF  RVVDK+WQ  +  D  +++  + +LISQ ++R   ++ E++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G N  G+        +TW+   P  I  D +  + ++ + L L    R     +W E+  +KKQ+LE+ FK+      +   ++ ++ P IE+  L+ W +++  E   T+          +P S  + S +++G  +S         KL    RN     L+                        +++S +E   W+  HI+VV++L+D     + +++   + Y+  +W   E EL RERGLWGP +GS LDKWML+  EGPCRMRKK++ N+ FY HYPY P       + E+     +  +++ A S D +              D Y +L P    N +    TVEE+ +   ++ +PE    +T + ++G            P+K      D  +D           E++E      M  D +        +E +S  E        ++ +DS+ ++                             ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY++DGFT+  TREI +I  +P+++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+      IN  +  M+ L      +++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STV+ VW    +  K               A +L+L+  L GH + VTCL  + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT  GRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP + +   AD  E P     +  G E+       S+ E+    Q+   + S+   N S     + +   ++  + D  SD+         S++++ D        +DG   V  + N SKVQ   ++S    SQ  +R +  KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ +    RN
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENEL-----------------PL-AERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDR----------------HVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPDDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENLQVSAPV-----------ISSRSNRSCQFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIP-------DAEHETNTMKPARYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGQEAQDDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3479          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:100496744])

HSP 1 Score: 2419.81 bits (6270), Expect = 0.000e+0
Identity = 1477/3892 (37.95%), Postives = 2175/3892 (55.88%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFD-----------NXXXXXXXXXXXXXXXXHYLKTIVSDSSF-IP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRP--YHRS---PCDNNENHCQ-VYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQP-GFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F ++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL V+ +L+      ++CM T S+PST +KCLY+FFDLP+ P+I    + +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+   NE+ +D+++  + LI  LTT G  EL+P   L+    + + GF +P P  K  S+RN  AF+VLQ+ FL A+T +L   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+      +    K  ++ I H+ IFK+V K++G+LE+ VN LH YA  LK       EQ    ++    EQ +L L++++ LT+L+   + N  +FR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L IVL+ESHR R VFRKV  FV     LV +E   S   +  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +AIR LGCF           S  +   N   S+NQ F+   L  D +  + V                 +L  CS+          +  ++Y  A + FD           N   L           K ++   VS SS   P   + MKL    S+++   ++I+HP A++S++ L+ ++  D +Q  H ++LQ+ I   L  L   +RN Q+MCE+  +   LL+    A+ NE+HPLH     +FERLA+Q + P  +R+FLRL DPL C                S+  Y+P   +   +   G G D  FC       R N        G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLPS+AP +  +  +    +         G G   R+FPP  G ++STW C++  SS    HP+RLL+L R    S +   CLNI ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL+ T KL+Y+      S  +   ++++VYAYIGT P   ++S L WR GP HF+EE LTA+ V  I  LGPNY+G+FQ    P  D ++  GSL     V EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HN+AGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ L KKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R         D  L+ +++  +   +++ P    I+  LS L++   S     +DL RFGQF+  TL      E  + +  NN+  LE     +F   +   LI +RN    ++LK+L  S    T   +  EEL+K LGFDW ++FM+  +H +TV  AMR LV LLS P  +L+F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQSLLP H  +P +YF+L+ L L   +  +P+NL+ + P            IS  +N+S QF+ +S+  F+FG            +SG+ +++                            +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +   + +  +FL  L  +++P +           D  + S  ++   F+ +S +  +++E C           M T   L + PA+K + DF ++++++   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GG+Y  + NN++YF  RVVDK+WQ  +  D  +++  + +LISQ ++R   ++ E++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G N  G+        +TW+   P  I  D +  + ++ + L L    R     +W E+  +KKQ+LE+ FK+      +   ++ ++ P IE+  L+ W +++  E   T+          +P S  + S +++G  +S         KL    RN     L+                        +++S +E   W+  HI+VV++L+D     + +++   + Y+  +W   E EL RERGLWGP +GS LDKWML+  EGPCRMRKK++ N+ FY HYPY P   H +    C N    C+ + Q  +++ A S D +              D Y +L P    N +    TVEE+ +   ++ +PE    +T + ++G            P+K      D  +D           E++E      M  D +        +E +S  E        ++ +DS+ ++                             ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY++DGFT+  TREI +I  +P+++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+      IN  +  M+ L      +++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STV+ VW    +  K               A +L+L+  L GH + VTCL  + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT  GRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP + +   AD  E P     +  G E+       S+ E+    Q+   + S+   N S     + +   ++  + D  SD+         S++++ D        +DG   V  + N SKVQ   ++S    SQ  +R +  KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ +    RN
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENELP------------------LAERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDSRAEQIPPCLTNETSLPSPWGTPAVSRKRHVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPGADDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENLQVSAPV-----------ISSRSNRSCQFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIPDAEHETNTMVCFNKICSCKCIGQKSRYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGQEAQDDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3522          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: WDFY3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:100496744])

HSP 1 Score: 2410.18 bits (6245), Expect = 0.000e+0
Identity = 1466/3884 (37.74%), Postives = 2159/3884 (55.59%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFD-----------NXXXXXXXXXXXXXXXXHYLKTIVSDSSF-IP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F ++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL V+ +L+      ++CM T S+PST +KCLY+FFDLP+ P+I    + +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+   NE+ +D+++  + LI  LTT G  EL+P   L+    + + GF +P P  K  S+RN  AF+VLQ+ FL A+T +L   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+      +    K  ++ I H+ IFK+V K++G+LE+ VN LH YA  LK       EQ    ++    EQ +L L++++ LT+L+   + N  +FR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L IVL+ESHR R VFRKV  FV     LV +E   S   +  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +AIR LGCF           S  +   N   S+NQ F+   L  D +  + V                 +L  CS+          +  ++Y  A + FD           N   L           K ++   VS SS   P   + MKL    S+++   ++I+HP A++S++ L+ ++  D +Q  H ++LQ+ I   L  L   +RN Q+MCE+  +   LL+    A+ NE+HPLH     +FERLA+Q + P  +R+FLRL DPL C                S+  Y+P   +   +   G G D  FC       R N        G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLPS+AP +  +  +    +         G G   R+FPP  G ++STW C++  SS    HP+RLL+L R    S +   CLNI ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL+ T KL+Y+      S  +   ++++VYAYIGT P   ++S L WR GP HF+EE LTA+ V  I  LGPNY+G+FQ    P  D ++  GSL     V EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HN+AGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ L KKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R         D  L+ +++  +   +++ P    I+  LS L++   S     +DL RFGQF+  TL      E  + +  NN+  LE     +F   +   LI +RN    ++LK+L  S    T   +  EEL+K LGFDW ++FM+  +H +TV  AMR LV LLS P  +L+F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQSLLP H  +P +YF+L+ L L   +  +P+NL                         QF+ +S+  F+FG            +SG+ +++                            +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +   + +  +FL  L  +++P +           D  + S  ++   F+ +S +  +++E C           M T   L + PA+K + DF ++++++   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GG+Y  + NN++YF  RVVDK+WQ  +  D  +++  + +LISQ ++R   ++ E++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G N  G+        +TW+   P  I  D +  + ++ + L L    R     +W E+  +KKQ+LE+ FK+      +   ++ ++ P IE+  L+ W +++  E   T+          +P S  + S +++G  +S         KL    RN     L+                        +++S +E   W+  HI+VV++L+D     + +++   + Y+  +W   E EL RERGLWGP +GS LDKWML+  EGPCRMRKK++ N+ FY HYPY P       + E+     +  +++ A S D +              D Y +L P    N +    TVEE+ +   ++ +PE    +T + ++G            P+K      D  +D           E++E      M  D +        +E +S  E        ++ +DS+ ++                             ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY++DGFT+  TREI +I  +P+++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+      IN  +  M+ L      +++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STV+ VW    +  K               A +L+L+  L GH + VTCL  + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT  GRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP + +   AD  E P     +            S+ E+    Q+   + S+   N S     + +   ++  + D  SD+         S++++ D        +DG   V  + N SKVQ   ++S    SQ  +R +  KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ +    RN
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENELP------------------LAERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDSRAEQIPPCLTNETSLPSPWGTPAVSRKRHVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPGADDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENL-------------------------QFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIP-------DAEHETNTMKPARYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGLDCYDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3493          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: ENSXETT00000044622.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:7:37111747:37138184:1 gene:ENSXETG00000002289.1 transcript:ENSXETT00000044622.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 389.037 bits (998), Expect = 2.478e-118
Identity = 209/526 (39.73%), Postives = 307/526 (58.37%), Query Frame = 2
Query: 8975 MGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNM-EPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLE 10546
            MGAQ+  R  +F +RY++ ++  G+ +   HY THYSSA IV+ YLVR+EPFTQ    +QGG  DLADR+FH++   WESAS  NM+D++ELIPEF+YLP    N+N   LG  Q+G V+GD+LLPPWA GD + F+R H EALE +YVS+ ++ WIDL+FGYKQ G AAV A+NVFH  FY G+ D  +  DPL R+ +IGFI+NFGQ+PKQLF KPHP +          K++       SS      FY    ++ + ++ P   L+ AVG ++  +              +V A E+N  L+ P Y   ++WG+SDGSL++ N ++ K++ V+E+   +G    V+C +  I+IT   S+V+ VW  S    K   S              L L+  L GH  AV C+  +  Y +L+SGS D +CI+WDL  +  +R+L  H   V  + +++ TG   SC  + L++WS++G+ L  +   +     IL+     +      +V++TG  DG+VR W +E
Sbjct:    1 MGAQTRERSQKFIQRYKDVENNDGDLSVQCHYCTHYSSASIVSSYLVRVEPFTQAMRWVQGGPLDLADRLFHNVAGVWESASSENMSDVRELIPEFYYLPEMFINSNHCQLGCMQDGTVVGDVLLPPWAHGDPQSFVRLHSEALESEYVSSQIHHWIDLVFGYKQRGPAAVHALNVFHPYFY-GSPDYLNSTDPLVRTTLIGFISNFGQVPKQLFTKPHPLRH--------GKEL-------SSGHTVSPFYSAPCSLKQVTVTPRGNLRGAVGHMLVTE-------------KAVFAAEKNHVLLSPSYAMSLSWGYSDGSLKLQNRNTRKVVDVWELMSHWGWCHSVICPSPAIVITAMSSSVLCVWIFSPPGQKERES-------------ELQLKKVLTGHGSAVLCVCASVKYGVLISGSADGSCILWDLDNLKCVRKLPIHPREVTLVAVNDRTGAFVSCCHSDLYMWSVNGKPLTYIRVGS----NILSCCFGGL------SVIVTGSQDGIVRFWKME 474          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Match: LYST (lysosomal trafficking regulator [Source:NCBI gene;Acc:779601])

HSP 1 Score: 417.927 bits (1073), Expect = 5.338e-116
Identity = 259/748 (34.63%), Postives = 390/748 (52.14%), Query Frame = 2
Query: 8450 IDVHEPIVPSTPTVNTFNHRRKMSDKF--SFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPH---PTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNM----EPSLQP-VKELK--NAVG-------QIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCA-----GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
            I V +  +   P+  TF      +  F  ++ EI+EVHKR + L+  AVE+FL +GR  LLAF   K+++ IY               H+I      + +E G+ +         ++T  W  G+I+NF+YL +LN  AGRS++DLMQYPVFP+IL+DY +ETLDL+  + +R L KP+  QS+ +  ++   Y+            DDP     PYHYG+HYS++  V  +LVRM PFT+ FL  Q   FD+ DR FHS+K TW  +S  +M D+KELIPEFFYLP FL N   FD G +QNG  +  + LPPWA+ D R FI  HR+ALE D VS  +  WIDL+FGYKQ G AAV+A+NVFH   Y G +D+ +++DP++R A+   I  +GQ P+QLF   H   P  +LL+   +         P A     +  F  + D       PS  P +K LK    VG        +  +  +G    ++ ++P+  +     K  +  +Y++                 ++WG++D  LR+ +  S+  +   +  + +    C    +   L TG    V+  +      S P             L   +  Q +LYGH   +T L V   Y++L+S S+D TCI+WDL R+CY++ L+GH +PV A+  SE TG +A+       G+ L LW+++G+ +  V+      + I +V  S   +    NV+  G  +G+VR+WS
Sbjct: 2915 IRVTQRCINVAPSRETFGELLLEAASFAWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKIRDDIY---------------HNILNNNLPNLLEYGNIT---------ALTHLWCTGQITNFEYLTHLNKHAGRSFSDLMQYPVFPFILSDYFNETLDLSDSAIYRNLAKPIAVQSKEKEDRYIDNYKYLEDEYCKGDREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMKTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGLRQNGERVNHVNLPPWARNDPRLFILIHRQALESDNVSQTICHWIDLVFGYKQKGRAAVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFHSAHVSRPGSKLLMEGEL---------PAAMGLLVQLAFRDSRDTSRDVGHPSPLPWIKGLKWGEYVGSPSAPDPSVCFSQPHGERFGSLQALPTRAVCGLSGKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYADNILRLKSKQSEPPVNFIQCSELHQVTSCAWVPDSCQLFTGSKCGVITAYLNRFTNSTP-------------LEIEVESQVHLYGHTAEITSLFVCKPYSILISVSKDGTCIIWDLNRLCYVQSLTGHKSPVTAVSASETTGDIATVCDSVGGGSDLRLWTVNGDLIGHVHC----REIICSVAFSNQPEGVSVNVIAGGLENGIVRLWS 3611          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875])

HSP 1 Score: 1231.47 bits (3185), Expect = 0.000e+0
Identity = 883/2774 (31.83%), Postives = 1399/2774 (50.43%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKT-----------IVSDSSFIP----NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTY--------ISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE                 AG       P    RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+    E  +D+++ L+ L+  LTT G  EL+P   ++    + + GF +P P  K  S+RN  AF VLQ+ FL A+T+FL   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+ +    + + +K  ++   H+ IFK+V +++G+LE+ VN LH YA  LK    A     DS NN    +Q  L LL+++ LT+L+   + N  +FR+ GG+ C  ++V + + +  AL  I+ L LS   E+DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E   S   K  W+ + + ++LE +  +   LT AL+ EP+N  +F   + Y  L +A+R LGCF SD+  I   N    N+Q +                +E +VS+    D++         L  CS+          +  ++Y  A + FD+            S       T            VS     P      +KL V  S + +  ++I+HP A+++++ L+ ++     Q  H ++LQ+ +   L  L   +RN Q+MCE+  +   LL     A+ +E+H LH     +FERLA+Q + P  +R+FLRLA PL C            +   S+  ++P   +       G G D  F ++         S ++   G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLP  +    ++  ++       +  ++ G+G GER FPP  G S+S W C++ FSS    HP+RLL++ R    S +   CL I ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HL L   R GM+K+S+ + +L+GQL+ T KL+Y+      S  +   ++++VYAY+GT P   +I++L WR GP HF+EE L  S V+ I  LGPNY+G+FQ    P  D +      +P+ SLVAEEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HNAAGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL   L  R + L       P    I+  LS L++    + N  +DL RFGQF+  TL      E  + +  NN+   +    +    L+    +  +  L  +   +   + E      +  EEL++ LGFDWI++FM+  +HP+TV  AMR LV LLS    ++KF++G+   GWL  TD VL  + G +L  N          +REIN D+CH PGF+ LQS LP H  +P +YF+L+AL L   +  +P+NL+ + P T           S    Q  QF+ +S+  F+FG                       G +++ I                  +C+E+A +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +  S+ +  DFL  L   ++P +           D  + S  ++   F+ ++ +  +++E C           + T   L + PA+K + DF +++I+D   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  ++I ++ +LI+Q ++R   ++ +++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G ++ G+        +TW+        PD   + +I +   Q+    +N         +W E+  +KKQ+LEE FK+      +   ++    P IE+  LK W +++  E    +     R    +P +  + S +++G  +S         KL    RN     L                         +  S +E   W+  HI+VV++L+D     + +++   + Y+  +W  +E EL RERGLWGP +GS LDKWML+  EGPCRMRKKM+ N+ FY HYPY P         E    V +  +++ A S D + YY               +L+       S NP  V++ I        + ++PE    +T + ++G          S P  GD +  ++ QD   +   I  +E+E+T N
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPE-----------------AGGGAQNELPL-AERRGLLQKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQGKEAEC-RDALKDLVSLVTSLTTYGVSELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEALTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGEDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVSQSQVLELLHTVFCTLTAALRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAVNVFPSNTQPFQR------------LLEEGAVSV----DSV------SPTLRHCSK----------LFIYLYKVATDSFDSHAEQIPPCLTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTSSPLQSSDAVIIHPGAMLAMLDLLASVG-SVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCGAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSFEPEMRSSVITSLEGLGSDNVFSSHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLTDGAVVSGMGSGERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELVVEGQWHHLALLMSR-GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAVCVPCKDAKSEGVTPSPV-SLVAEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLVHNAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQ---GFPNS-NDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKPDPGAEEEFGGLVSANLILLRNRLLDILLKLVYTSKEKTNINLQACEELVRTLGFDWIMMFMEEHLHPTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFLVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVT-----------SSRCKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTESAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWLSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAG-SVEGFGLEAEARMTTWHIMIPSDIEPDGGYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVSLPVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCIS-----RGEALVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLHK-----------------------HSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVP-------ETEQEASVGKPARYRRAISYDSKEYYL--------------RLA-------SGNPAIVQDAIVESSEGEATQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSI--EEEEKTDN 2505          

HSP 2 Score: 1184.47 bits (3063), Expect = 0.000e+0
Identity = 566/1044 (54.21%), Postives = 736/1044 (70.50%), Query Frame = 2
Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWIL+DY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+   ++  N  I     +   A ++++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STVV VW M  +  K               A  L+L+  L GH + VTC   + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT TGRS+QI+   MS M +WD  NV++TG +DGVVR W +E++QVP + +    +  E Q    +      +   +SS+ E +E    +  + + S  + +       S  A +    D  SD+         S++++ D        +DG   +N  E    + +Q  L      P    +  +L+ G+ W+RQL+FRSKLTMHTA++R DN +P+ +++L +S+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+YS+  ++ +    RN
Sbjct: 2511 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGIS----VPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEDLEMQEGCPEAQIGQQAQDDDSSDSETEEPSVSQDPKDTSSQPSSTSHRPRAASCRATATWCTDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQTRAHLQGPLAHPHPNPIEARSYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRN 3507          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875])

HSP 1 Score: 1225.31 bits (3169), Expect = 0.000e+0
Identity = 884/2787 (31.72%), Postives = 1401/2787 (50.27%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKT-----------IVSDSSFIP----NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTY--------ISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGN-----REQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRS--------PCDNNENHCQVYQIKK---FKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE                 AG       P    RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+    E  +D+++ L+ L+  LTT G  EL+P   ++    + + GF +P P  K  S+RN  AF VLQ+ FL A+T+FL   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+ +    + + +K  ++   H+ IFK+V +++G+LE+ VN LH YA  LK    A     DS NN    +Q  L LL+++ LT+L+   + N  +FR+ GG+ C  ++V + + +  AL  I+ L LS   E+DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E   S   K  W+ + + ++LE +  +   LT AL+ EP+N  +F   + Y  L +A+R LGCF SD+  I   N    N+Q +                +E +VS+    D++         L  CS+          +  ++Y  A + FD+            S       T            VS     P      +KL V  S + +  ++I+HP A+++++ L+ ++     Q  H ++LQ+ +   L  L   +RN Q+MCE+  +   LL     A+ +E+H LH     +FERLA+Q + P  +R+FLRLA PL C            +   S+  ++P   +       G G D  F ++         S ++   G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLP  +    ++  ++       +  ++ G+G GER FPP  G S+S W C++ FSS    HP+RLL++ R    S +   CL I ++++ +  ++VSTKEE+  N      E+ ++ E           C  L+ E  W HL L   R GM+K+S+ + +L+GQL+ T KL+Y+      S  +   ++++VYAY+GT P   +I++L WR GP HF+EE L  S V+ I  LGPNY+G+FQ    P  D +      +P+ SLVAEEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HNAAGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL   L  R + L       P    I+  LS L++    + N  +DL RFGQF+  TL      E  + +  NN+   +    +    L+    +  +  L  +   +   + E      +  EEL++ LGFDWI++FM+  +HP+TV  AMR LV LLS    ++KF++G+   GWL  TD VL  + G +L  N          +REIN D+CH PGF+ LQS LP H  +P +YF+L+AL L   +  +P+NL+ + P T           S    Q  QF+ +S+  F+FG                       G +++ I                  +C+E+A +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +  S+ +  DFL  L   ++P +           D  + S  ++   F+ ++ +  +++E C           + T   L + PA+K + DF +++I+D   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  ++I ++ +LI+Q ++R   ++ +++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G ++ G+        +TW+        PD   + +I +   Q+    +N         +W E+  +KKQ+LEE FK+      +   ++    P IE+  LK W +++  E    +     R    +P +  + S +++G  +S         KL    RN     L                         +  S +E   W+  HI+VV++L+D     + +++   + Y+  +W  +E EL RERGLWGP +GS LDKWML+  EGPCRMRKKM+ N+ FY HYPY P            P    E    V   KK   ++ A S D + YY               +L+       S NP  V++ I        + ++PE    +T + ++G          S P  GD +  ++ QD   +   I  +E+E+T N
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPE-----------------AGGGAQNELPL-AERRGLLQKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQGKEAEC-RDALKDLVSLVTSLTTYGVSELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEALTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGEDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVSQSQVLELLHTVFCTLTAALRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAVNVFPSNTQPFQR------------LLEEGAVSV----DSV------SPTLRHCSK----------LFIYLYKVATDSFDSHAEQIPPCLTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTSSPLQSSDAVIIHPGAMLAMLDLLASV-GSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCGAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSFEPEMRSSVITSLEGLGSDNVFSSHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLTDGAVVSGMGSGERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFR--CGELVVEGQWHHLALLMSR-GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAVCVPCKDAKSEGVTPSPV-SLVAEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLVHNAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQ---GFPNS-NDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKPDPGAEEEFGGLVSANLILLRNRLLDILLKLVYTSKEKTNINLQACEELVRTLGFDWIMMFMEEHLHPTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFLVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVT-----------SSRCKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTESAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWLSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAG-SVEGFGLEAEARMTTWHIMIPSDIEPDGGYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVSLPVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCIS-----RGEALVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLHK-----------------------HSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQEASVGSEIPSKQPEPPDDVIAQKKPARYRRAISYDSKEYYL--------------RLA-------SGNPAIVQDAIVESSEGEATQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSI--EEEEKTDN 2523          

HSP 2 Score: 1184.47 bits (3063), Expect = 0.000e+0
Identity = 566/1044 (54.21%), Postives = 736/1044 (70.50%), Query Frame = 2
Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWIL+DY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+   ++  N  I     +   A ++++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STVV VW M  +  K               A  L+L+  L GH + VTC   + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT TGRS+QI+   MS M +WD  NV++TG +DGVVR W +E++QVP + +    +  E Q    +      +   +SS+ E +E    +  + + S  + +       S  A +    D  SD+         S++++ D        +DG   +N  E    + +Q  L      P    +  +L+ G+ W+RQL+FRSKLTMHTA++R DN +P+ +++L +S+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+YS+  ++ +    RN
Sbjct: 2529 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGIS----VPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEDLEMQEGCPEAQIGQQAQDDDSSDSETEEPSVSQDPKDTSSQPSSTSHRPRAASCRATATWCTDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQTRAHLQGPLAHPHPNPIEARSYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRN 3525          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy3 (WD repeat and FYVE domain containing 3 [Source:MGI Symbol;Acc:MGI:1096875])

HSP 1 Score: 1222.61 bits (3162), Expect = 0.000e+0
Identity = 878/2785 (31.53%), Postives = 1394/2785 (50.05%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKT-----------IVSDSSFIP----NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTY--------ISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGN-----REQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRS--------PCDNNENHCQVYQIKK---FKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+                +  AG       P    RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+    E  +D+++ L+ L+  LTT G  EL+P   ++    + + GF +P P  K  S+RN  AF VLQ+ FL A+T+FL   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+ +    + + +K  ++   H+ IFK+V +++G+LE+ VN LH YA  LK    A     DS NN    +Q  L LL+++ LT+L+   + N  +FR+ GG+ C  ++V + + +  AL  I+ L LS   E+DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E   S   K  W+ + + ++LE +  +   LT AL+ EP+N  +F   + Y  L +A+R LGCF SD+  I   N    N+Q +                +E +VS+    D++         L  CS+          +  ++Y  A + FD+            S       T            VS     P      +KL V  S + +  ++I+HP A+++++ L+ ++     Q  H ++LQ+ +   L  L   +RN Q+MCE+  +   LL     A+ +E+H LH     +FERLA+Q + P  +R+FLRLA PL C            +   S+  ++P   +       G G D  F ++         S ++   G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLP  +    ++  ++       +  ++ G+G GER FPP  G S+S W C++ FSS    HP+RLL++ R    S +   CL I ++++ +  ++VSTKEE+  N      E+ ++ E           C  L+ E  W HL L   R GM+K+S+ + +L+GQL+ T KL+Y+      S  +   ++++VYAY+GT P   +I++L WR GP HF+EE L  S V+ I  LGPNY+G+FQ    P  D +      +P+ SLVAEEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HNAAGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL   L  R + L       P    I+  LS L++    + N  +DL RFGQF+  TL      E  + +  NN+   +    +    L+    +  +  L  +   +   + E      +  EEL++ LGFDWI++FM+  +HP+TV  AMR LV LLS    ++KF++G+   GWL  TD VL  + G +L  N          +REIN D+CH PGF+ LQS LP H  +P +YF+L+AL L   +  +P+NL                         QF+ +S+  F+FG                       G +++ I                  +C+E+A +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +  S+ +  DFL  L   ++P +           D  + S  ++   F+ ++ +  +++E C           + T   L + PA+K + DF +++I+D   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  ++I ++ +LI+Q ++R   ++ +++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G ++ G+        +TW+        PD   + +I +   Q+    +N         +W E+  +KKQ+LEE FK+      +   ++    P IE+  LK W +++  E    +     R    +P +  + S +++G  +S         KL    RN     L                         +  S +E   W+  HI+VV++L+D     + +++   + Y+  +W  +E EL RERGLWGP +GS LDKWML+  EGPCRMRKKM+ N+ FY HYPY P            P    E    V   KK   ++ A S D + YY               +L+       S NP  V++ I        + ++PE    +T + ++G          S P  GD +  ++ QD   +   I  +E+E+T N
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPH----------------VPEAGGGAQNELPL-AERRGLLQKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQGKEAEC-RDALKDLVSLVTSLTTYGVSELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEALTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGEDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVSQSQVLELLHTVFCTLTAALRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAVNVFPSNTQPFQR------------LLEEGAVSV----DSV------SPTLRHCSK----------LFIYLYKVATDSFDSHAEQIPPCLTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTSSPLQSSDAVIIHPGAMLAMLDLLASV-GSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCGAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSFEPEMRSSVITSLEGLGSDNVFSSHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLTDGAVVSGMGSGERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFR--CGELVVEGQWHHLALLMSR-GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAVCVPCKDAKSEGVTPSPV-SLVAEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLVHNAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQ---GFPNS-NDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKPDPGAEEEFGGLVSANLILLRNRLLDILLKLVYTSKEKTNINLQACEELVRTLGFDWIMMFMEEHLHPTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFLVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENL-------------------------QFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTESAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWLSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAGSSVEGFGLEAEARMTTWHIMIPSDIEPDGGYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVSLPVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCIS-----RGEALVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLHK-----------------------HSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQEASVGSEIPSKQPEPPDDVIAQKKPARYRRAISYDSKEYYL--------------RLA-------SGNPAIVQDAIVESSEGEATQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSI--EEEEKTDN 2509          

HSP 2 Score: 1184.47 bits (3063), Expect = 0.000e+0
Identity = 566/1044 (54.21%), Postives = 736/1044 (70.50%), Query Frame = 2
Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWIL+DY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+   ++  N  I     +   A ++++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STVV VW M  +  K               A  L+L+  L GH + VTC   + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT TGRS+QI+   MS M +WD  NV++TG +DGVVR W +E++QVP + +    +  E Q    +      +   +SS+ E +E    +  + + S  + +       S  A +    D  SD+         S++++ D        +DG   +N  E    + +Q  L      P    +  +L+ G+ W+RQL+FRSKLTMHTA++R DN +P+ +++L +S+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+YS+  ++ +    RN
Sbjct: 2515 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGIS----VPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEDLEMQEGCPEAQIGQQAQDDDSSDSETEEPSVSQDPKDTSSQPSSTSHRPRAASCRATATWCTDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQTRAHLQGPLAHPHPNPIEARSYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRN 3511          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy4 (WD repeat and FYVE domain containing 4 [Source:MGI Symbol;Acc:MGI:3584510])

HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0
Identity = 347/815 (42.58%), Postives = 490/815 (60.12%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG----EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVS 10639
            + QV ++ ++   EK+        +QG  V EG+LLFGQ +FYI + FTL  T ++   ++   ++ +P +        FN   + + SD +S     + ++RE+ + R+LLQ IA+E+F  +G + LL F    ++K    F           Q S+ G+        G+T    N       ++++ QRW+K EISNF+YLMYLNTLAGR+YND MQYPVFPW+LADY SE L+LT+P TFR L KPMGAQ++ R  +F +R+++ +   G+ T   HY THYSSA+IVA YLVRM PFTQ F  LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N  + G  Q+G  LGD+ LPPWA GD R+FI  HR+ALE D+VS++L+ WIDLIFGYKQ G AAVEAVN FH  FY   +D+ SI DPL +S ++GFI+NFGQ+PKQ+F KPHP++          K  D   P+     ++  F H+L  + PS   VK++          K A+G I+  +              S+LAVE+NK L+PPL+ R  +WGF D S  +G+Y SDK++  +E    +G  +C +C +  +++T G S VV +W +S+   +P                 L L+  LYGH +AVTCL  + +++LLVSGS+DRTCI+WDL  +  +  L  H   ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G    I    +     WD  +V+ITG  DG+VR+W  E V++P+            QAV  +P  E +S
Sbjct: 2374 ERQVILQELL-DGEKVSQKVPMVIVQGHLVSEGILLFGQHHFYICENFTLSPTGDVYCTHHCLSNISDPFI--------FNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNSDRSKALKSFSTF--------QPSLKGK--------GTTEDPFNLRKHPGFDRTMLQRWQKREISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQTKERKLKFTQRFKDVEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKSTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGCMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLGSITDPLIKSTILGFISNFGQVPKQIFTKPHPSRNTTGKNPGPGK--DASTPVGLPGHSQS-FLHSLPALRPSQVTVKDMYLFSLGSESPKGAIGHIVPTE-------------KSILAVEKNKLLMPPLWNRTFSWGFDDFSCCLGSYGSDKILMTFENLAAWGPCLCAVCPSPTMIVTSGASAVVCIWELSLVKGRPR---------------GLKLRQALYGHTQAVTCLTASVTFSLLVSGSQDRTCILWDLDHLSRVACLPVHREGISAIAISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGTITCCCIVEGPAWDASHVIITGSKDGMVRIWKTEDVKMPVPR----------QAVMEEPSTEPLS 3122          

HSP 2 Score: 322.783 bits (826), Expect = 3.061e-87
Identity = 279/1011 (27.60%), Postives = 470/1011 (46.49%), Query Frame = 2
Query: 2690 IIVHPEAVISLIHLIPAIRC-DQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLA----DPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVF---GNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGS---LVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEP---LSKLIELIISYSNK------PDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGW----LTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKE 5647
            +I+HP  +  ++ L+P +   D  Q +   E+Q  +   L  L   ++N Q+MCE+  M   L+      +      LHS+ + +FE+L +Q + P  +R FL L          + + +     +    + +C        +      GS     ++ SQ         +L    SLI +T+ +N                      R A  PSFVE +M  EG+GCLF P+++    +S   S+   +              R FPP GG +FS W  + + +++   HP+R L+L R L  + +   C +IS+    +  ++VST+E+ F      E E+ +E ++   +    C  LL    W HL +   +  M ++ S + +L+GQ I + K+ YI     S F    +    VY YIGT     + S+L WR GP +  EE ++A  ++ I +LGP Y GNFQ   L  E+P G    L+AEE+V F LY  + SI ++  I   YNE+D  +IA+++++  ++ ++P+ ++ N AGHLSG  R+LGA+ +G  G+R F  +P    +D +GG  +LLG++++A D   +YA +K++ S L  N ++   L  H+ GY++++FLL+KK   L+ RIF L++ + G+A+  F+   +                 N  +F  V+C+  LW +        + L   +  H+ E  Q             R+ +      +L  LL L                      NEP   LSK+  +I     +        DL R G F+++TL     +E +I L+   +     A  + +   I +RN   +++  ++++S    T+E K  E++   LG DW LL +Q  +HPST  LA++ L+  LS P    +FRDG+    W    + G D+V         MDN + +PA   +     C LPGF  L   L +H  IP++Y ++ +  L   +  + +  +E
Sbjct:  826 MIMHPGIICIMVRLLPRLYLEDHPQLSE--EIQCSVARHLLSLVKSEKNRQVMCEA-GMLRTLMTFCPRTLSTGGSDLHSILIRIFEKLGSQAIEPDVLRQFLGLGIRPPRSAAVKSLHLPPGHEDNPGCSGSCAATAEKPTDSSPRPGGSQALRPSWASQYSA-----TALQTTLSLISMTSPRN------------------LQPQRAALTPSFVEFDMSSEGYGCLFTPTLSTVMGTSTEHSISGGTGSGAP---------RPFPPPGGLTFSCWFLISRQANVMEGHPLRFLTLVRHLARTEQPFVCFSISLCMD-DLSLVVSTEEKEFQPLDAMEPEDEAEPSAGRQLQVR-CSQLLTCGQWYHLAVVVSKE-MKRNCSVTTYLDGQAIGSAKMLYIQALPGSFFSMDPSSFVDVYGYIGTPRVWKQKSSLTWRLGPAYLFEEDISADTLALIIKLGPRYCGNFQAVHLQGEDPDGEATPLIAEERVSFGLYVPSSSITSIMNIRNTYNEVDSRLIAKEMNISSRDNATPVFLLRNCAGHLSGPLRTLGAVAVGQLGVRVFHSSPAASSLDYIGGPAILLGLISLATDDHTMYAAMKVLHSVLTSN-AMCDYLMQHICGYQILAFLLRKKTSFLNHRIFQLILSVAGTAELGFRPSAVT----------------NMCIFQHVLCNFELWTN------TADNLELTLFSHLLEILQS-------PREGPRNAEVAHQAQLLPKLLFL---------------------FNEPSLALSKVSTIIAILGCQLKGHFNIQDLLRVGLFVIYTLKPSSVNERQICLD-GAQDPSRPAGSQTSGKAIWLRNQLLEMLFGVISSSQLHLTSELK--EQVFLSLGPDWFLLLLQGHLHPSTTTLALKLLLYFLSSPPLRGRFRDGLSAGCWVENCMDGVDIV---------MDNLKSRPAVPDQ---SPCLLPGFRVLNDFLAYHVLIPEVYLIVSSFFLQTPLTELTNGPRE 1732          

HSP 3 Score: 157.918 bits (398), Expect = 2.520e-37
Identity = 162/684 (23.68%), Postives = 313/684 (45.76%), Query Frame = 2
Query:  272 FQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284
            F+ +      VS  + +EI++    +  E+A  A  Q LQ        + +  G +LL  + +L+   +  +  ++ + LP+  ++CLY+FF  P          + D +      G +                  F Q+L  IC      E L+   +L+ L   +A+ C   +S   W++    VL+ I+    S S IQ++     +   ++N++K    L + E+ +    + + +R+S  ++  LL +F N +GY ++ + L++         E   +  LI L+  LTTCG  EL+    +   + YP +EGF+     +   +++N  AF VLQ++F  A    LC+++L AIKT++  +P N+F+LE        F+E +  K   VQE    L++ +V  L YVP + ++ +  ++K  +    T + +++ +R+   +++F ++ +D G+L + + QL   A  ++K  +   S  V + + EL  +++  +  L+    +N  + +  G       +V F+K        +  +L  ++ L++ + +EE MS  +G + S ++Q        L    + + E+ +    FR    F   +  L  LEG   +        +   + LE V   L +++ AL  +P N  +F  N  +  L E +  LGCFG+
Sbjct:   89 FRSLQRLAEDVSDQLAQEIQQALAGKPAEQARAAAGQLLQ-----WKSDADQDGNLLLKSVYVLTGTDSETLGRVVDSGLPALLLQCLYLFFAFP---------VEKDDLLESDVQGQRM-----------------FVQMLLNICSESQGLEGLLSGSELQSLL--IATTCLREHSCLFWKQPTFCVLRAIS-KAQSPSVIQYLRTADCVRLSVQNLSKLADTLPAPEVSEAVSLILNFVRDSYPISSALLLEFENGEGYPLLLKVLLRYNGLTQGVVE-PHLEELIELVMWLTTCGRSELK----VFDSVTYPQLEGFKFHQEAS-GVTVKNLQAFQVLQNLFHRASDSVLCIQVLLAIKTMWAWNPRNFFLLEWTLQPISQFAEIIPLKPTPVQEHFFQLLETLVFKLLYVPHEVLAKVQRLIKESSELSCTLVALRSILRITASDRLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKECSPDVQDPERELTYVMLSTVVTLLQGSVRNAVVLKDHG-------MVPFIKIFLDDECYRGPSLSILEQLSVIN-AEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILETPKGHAAFRVSSGFNGLLSLLSDLEGSLQVPEVTTCGAVSPSQTLELVLHTLCVVSAALHLDPVNEHFFRSNGLFEKLAEDLCLLGCFGT 723          

HSP 4 Score: 61.6178 bits (148), Expect = 3.020e-8
Identity = 62/279 (22.22%), Postives = 120/279 (43.01%), Query Frame = 2
Query: 5900 MCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHV-IDIILECDIENTTQEHMKQFQTVFMNSLTEHFM-----AVDILSGQNLPLPPGGSYANIPN--NIYYFFSRVVDKVWQENYVDDPDVIISYLCRLI-----SQGRKRQITQESLYRSFNRLILFRLSR 6697
            +C E A +LL M++ ++NQ      + +  W +  P ++L+ F+ L H +    S     DFL  +    +P       +S    N  SP +     +   G               S    PA + + +F ++++ +      N  Q + +++ILE   +  T +  + FQT  + S  + F       +  L G   PLP   + A +P+  ++ YF  ++V+K++   +  DP  I+ ++   I     +   ++     +LY S N++IL  LS+
Sbjct: 1755 LCIEGALLLLGMLKAIMNQ--PPAGSGDGAWEQTLPSSVLQ-FLRLVHRSYPQDSAWRTPDFLQTVAIITFPLETQKETTSESSRNTSSPGASAEASHAAEG------------FQASFQPHPALRQLREFMQVLLRELLLGGSNPKQWLPLEVILEASPDGATSQQKRDFQTEVLLSTMDIFQVPSGDGMPTLRGSKEPLPNAEAGA-VPSLASVSYFTQKLVEKIYSGVFSADPRHILLFITEHIIAVIENPSSQKDTVMSALYSSLNKVILHCLSK 2017          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Match: Wdfy4 (WD repeat and FYVE domain containing 4 [Source:MGI Symbol;Acc:MGI:3584510])

HSP 1 Score: 647.121 bits (1668), Expect = 0.000e+0
Identity = 347/815 (42.58%), Postives = 490/815 (60.12%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG----EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVS 10639
            + QV ++ ++   EK+        +QG  V EG+LLFGQ +FYI + FTL  T ++   ++   ++ +P +        FN   + + SD +S     + ++RE+ + R+LLQ IA+E+F  +G + LL F    ++K    F           Q S+ G+        G+T    N       ++++ QRW+K EISNF+YLMYLNTLAGR+YND MQYPVFPW+LADY SE L+LT+P TFR L KPMGAQ++ R  +F +R+++ +   G+ T   HY THYSSA+IVA YLVRM PFTQ F  LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N  + G  Q+G  LGD+ LPPWA GD R+FI  HR+ALE D+VS++L+ WIDLIFGYKQ G AAVEAVN FH  FY   +D+ SI DPL +S ++GFI+NFGQ+PKQ+F KPHP++          K  D   P+     ++  F H+L  + PS   VK++          K A+G I+  +              S+LAVE+NK L+PPL+ R  +WGF D S  +G+Y SDK++  +E    +G  +C +C +  +++T G S VV +W +S+   +P                 L L+  LYGH +AVTCL  + +++LLVSGS+DRTCI+WDL  +  +  L  H   ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G    I    +     WD  +V+ITG  DG+VR+W  E V++P+            QAV  +P  E +S
Sbjct: 2215 ERQVILQELL-DGEKVSQKVPMVIVQGHLVSEGILLFGQHHFYICENFTLSPTGDVYCTHHCLSNISDPFI--------FNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNSDRSKALKSFSTF--------QPSLKGK--------GTTEDPFNLRKHPGFDRTMLQRWQKREISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQTKERKLKFTQRFKDVEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKSTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGCMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLGSITDPLIKSTILGFISNFGQVPKQIFTKPHPSRNTTGKNPGPGK--DASTPVGLPGHSQS-FLHSLPALRPSQVTVKDMYLFSLGSESPKGAIGHIVPTE-------------KSILAVEKNKLLMPPLWNRTFSWGFDDFSCCLGSYGSDKILMTFENLAAWGPCLCAVCPSPTMIVTSGASAVVCIWELSLVKGRPR---------------GLKLRQALYGHTQAVTCLTASVTFSLLVSGSQDRTCILWDLDHLSRVACLPVHREGISAIAISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGTITCCCIVEGPAWDASHVIITGSKDGMVRIWKTEDVKMPVPR----------QAVMEEPSTEPLS 2963          

HSP 2 Score: 295.434 bits (755), Expect = 5.451e-79
Identity = 237/803 (29.51%), Postives = 394/803 (49.07%), Query Frame = 2
Query: 3299 RFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVF---GNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGS---LVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEP---LSKLIELI------ISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGW----LTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKE 5647
            R A  PSFVE +M  EG+GCLF P+++    +S   S+   +              R FPP GG +FS W  + + +++   HP+R L+L R L  + +   C +IS+    +  ++VST+E+ F      E E+ +E ++   +    C  LL    W HL +   +  M ++ S + +L+GQ I + K+ YI     S F    +    VY YIGT     + S+L WR GP +  EE ++A  ++ I +LGP Y GNFQ   L  E+P G    L+AEE+V F LY  + SI ++  I   YNE+D  +IA+++++  ++ ++P+ ++ N AGHLSG  R+LGA+ +G  G+R F  +P    +D +GG  +LLG++++A D   +YA +K++ S L  N ++   L  H+ GY++++FLL+KK   L+ RIF L++ + G+A+  F+   +                 N  +F  V+C+  LW +        + L   +  H+ E  Q   +         R+ +      +L  LL L                      NEP   LSK+  +I      +       DL R G F+++TL     +E +I L+   +     A  + +   I +RN   +++  ++++S    T+E  + E++   LG DW LL +Q  +HPST  LA++ L+  LS P    +FRDG+    W    + G D+V         MDN + +PA   +     C LPGF  L   L +H  IP++Y ++ +  L   +  + +  +E
Sbjct:  963 RAALTPSFVEFDMSSEGYGCLFTPTLSTVMGTSTEHSISGGTGSGAP---------RPFPPPGGLTFSCWFLISRQANVMEGHPLRFLTLVRHLARTEQPFVCFSISLCMD-DLSLVVSTEEKEFQPLDAMEPEDEAEPSAGRQLQVR-CSQLLTCGQWYHLAVVVSKE-MKRNCSVTTYLDGQAIGSAKMLYIQALPGSFFSMDPSSFVDVYGYIGTPRVWKQKSSLTWRLGPAYLFEEDISADTLALIIKLGPRYCGNFQAVHLQGEDPDGEATPLIAEERVSFGLYVPSSSITSIMNIRNTYNEVDSRLIAKEMNISSRDNATPVFLLRNCAGHLSGPLRTLGAVAVGQLGVRVFHSSPAASSLDYIGGPAILLGLISLATDDHTMYAAMKVLHSVLTSN-AMCDYLMQHICGYQILAFLLRKKTSFLNHRIFQLILSVAGTAELGFRPSAVT----------------NMCIFQHVLCNFELWTN------TADNLELTLFSHLLEILQSPREGP-------RNAEVAHQAQLLPKLLFL---------------------FNEPSLALSKVSTIIAILGCQLKGHFNIQDLLRVGLFVIYTLKPSSVNERQICLD-GAQDPSRPAGSQTSGKAIWLRNQLLEMLFGVISSSQLHLTSE--LKEQVFLSLGPDWFLLLLQGHLHPSTTTLALKLLLYFLSSPPLRGRFRDGLSAGCWVENCMDGVDIV---------MDNLKSRPAVPDQ---SPCLLPGFRVLNDFLAYHVLIPEVYLIVSSFFLQTPLTELTNGPRE 1687          

HSP 3 Score: 155.221 bits (391), Expect = 1.597e-36
Identity = 162/684 (23.68%), Postives = 313/684 (45.76%), Query Frame = 2
Query:  272 FQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284
            F+ +      VS  + +EI++    +  E+A  A  Q LQ        + +  G +LL  + +L+   +  +  ++ + LP+  ++CLY+FF  P          + D +      G +                  F Q+L  IC      E L+   +L+ L   +A+ C   +S   W++    VL+ I+    S S IQ++     +   ++N++K    L + E+ +    + + +R+S  ++  LL +F N +GY ++ + L++         E   +  LI L+  LTTCG  EL+    +   + YP +EGF+     +   +++N  AF VLQ++F  A    LC+++L AIKT++  +P N+F+LE        F+E +  K   VQE    L++ +V  L YVP + ++ +  ++K  +    T + +++ +R+   +++F ++ +D G+L + + QL   A  ++K  +   S  V + + EL  +++  +  L+    +N  + +  G       +V F+K        +  +L  ++ L++ + +EE MS  +G + S ++Q        L    + + E+ +    FR    F   +  L  LEG   +        +   + LE V   L +++ AL  +P N  +F  N  +  L E +  LGCFG+
Sbjct:   89 FRSLQRLAEDVSDQLAQEIQQALAGKPAEQARAAAGQLLQ-----WKSDADQDGNLLLKSVYVLTGTDSETLGRVVDSGLPALLLQCLYLFFAFP---------VEKDDLLESDVQGQRM-----------------FVQMLLNICSESQGLEGLLSGSELQSLL--IATTCLREHSCLFWKQPTFCVLRAIS-KAQSPSVIQYLRTADCVRLSVQNLSKLADTLPAPEVSEAVSLILNFVRDSYPISSALLLEFENGEGYPLLLKVLLRYNGLTQGVVE-PHLEELIELVMWLTTCGRSELK----VFDSVTYPQLEGFKFHQEAS-GVTVKNLQAFQVLQNLFHRASDSVLCIQVLLAIKTMWAWNPRNFFLLEWTLQPISQFAEIIPLKPTPVQEHFFQLLETLVFKLLYVPHEVLAKVQRLIKESSELSCTLVALRSILRITASDRLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKECSPDVQDPERELTYVMLSTVVTLLQGSVRNAVVLKDHG-------MVPFIKIFLDDECYRGPSLSILEQLSVIN-AEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILETPKGHAAFRVSSGFNGLLSLLSDLEGSLQVPEVTTCGAVSPSQTLELVLHTLCVVSAALHLDPVNEHFFRSNGLFEKLAEDLCLLGCFGT 723          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q8IZQ1|WDFY3_HUMAN (WD repeat and FYVE domain-containing protein 3 OS=Homo sapiens OX=9606 GN=WDFY3 PE=1 SV=2)

HSP 1 Score: 1237.25 bits (3200), Expect = 0.000e+0
Identity = 890/2784 (31.97%), Postives = 1405/2784 (50.47%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXX------------XXXXXXXXXXXXHYLKTIVSDSSFIPN---PMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD----------FCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKI--AEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRS--------PCDNNENHCQVYQIK--KFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE     Q +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+    E+ +D+++ L+ LI  LTT G  EL+P   ++    + + GF +P P  K  S+RN  AF VLQ+ FL A+T FL   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+ +    + + +K  ++   H+ IFK+V +++G+LE+ VN LH YA  LK    A     DS NN    +Q  L LL+++ LT+L+   + N  +FR+ GG+ C  ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E   S   K  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +A+R LGCF SD+  I   N    N+Q        +   L  D     SVS                 L  CS+          +  ++Y  A + FD+R                       S  +H   ++ +   + P     +KL V  SS+ +  ++I+HP A+++++ L+ ++     Q  H ++LQ+ +   L  L   +RN Q+MCE+  +   LL     A+ +E+H LH     +FERLA+Q + P  +R+FLRLA PL C            +   S+  Y+P   +       G G D          +    S ++   G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLP  +    ++  ++      I+  ++ GIG GER FPP  G S+S+W C++ FSS    HP+RLL++ R    S +   CL I ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL++T KL+Y+      S  +   ++++VYAYIGT P   +I++L WR GP HF+EE L +S V+ I  LGPNY+G+FQ    P  D +      +P+ SLV EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P+++IHN+AGHL+G+ R++GA LIGY G+R F P P+   +  VGG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL   L  R + L       P    I+  LS L++   S     +DL RFGQF+  TL      E  + +  NN+  L++    EF   +    I      + + +     + E     +   EEL+K LGFDWI++FM+  +H +TV  AMR LV LLS    ++KF++G+   GWL  TD VL  + G +L  N          +REIN D+CH PGF  LQS LP H  +P +YF+L+AL L   +  +P+NL+ + P            ISC + Q  QF+ +S+  F+FG                       G +++ I                  +C+EA  +LL M+R ML         E  +W+R+YP+TL++FF YLYH+  +  S+ M  DFL  L   ++P +           D  + S  ++   F+ ++ +  +++E C           + T   L + PA+K + DF +++I+D   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  ++I ++ +LI+Q ++R   ++ +++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G N+ G+        +TW+        PD   + +I +   Q+    +N         +W E+  +KKQ+LEE FK+      +   ++ +  P IE+  LK W +++  E                         I+ G  ++ + Q     KL+R+S    L +L+ S      SG              + +S +E   W+  HI+VV++L+D     + +++   + Y+  +W  +E EL RERGLWGP +GS LDKWML+  EGPCRMRKKM+ N+ FY HYPY P            P    E    + Q K  +++ A S D + Y              Y +L+       S NP  V++ I        + ++PE    +T + ++G          S P  GD +  ++ QD   +   I  +E+E+T N
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEAVGGAQNELP------------------LAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAES-KDALKDLVNLITSLTTYGVSELKPA-GITTGAPFLLPGFAVPQPAGKGHSVRNVQAFAVLQNAFLKAKTSFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNEQGDSRNNSSVEDQKHLALLVMETLTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAMNVFPSNTQP-------FQRLLEEDVISIESVS---------------PTLRHCSK----------LFIYLYKVATDSFDSRAEQIPPCLTSESSLPSPWGTPALSRKRHAYHSVSTPPVYPPKNVADLKLHVTTSSLQSSDAVIIHPGAMLAMLDLLASV-GSVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSYEPEMRSSMITSLEGLGTDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLIDGAVVSGIGSGERFFPPPSGLSYSSWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELIIEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVNTVKLHYVHSTPGGSGSANPPVVSTVYAYIGTPPAQRQIASLVWRLGPTHFLEEVLPSSNVTTIYELGPNYVGSFQAVCMPCKDAKSEGVVPSPV-SLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLIHNSAGHLNGSARTIGAALIGYLGVRTFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQGFPS----SNDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKLDTGTEEEFGGLVSANLILLRNRLLDILLKLIYTSKEKTSINLQACEELVKTLGFDWIMMFMEEHLHSTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPV-----------ISCRSKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTEAVFLLLGMLRSMLTSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSNVDGFGLEAEARMTTWHIMIPSDIEPDGSYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVTLPVNERGHVDIATARPLIEEAALKCWQNHLAHEK----------------------KCISRGEALAPTTQS----KLSRVSSGFGLSKLTGSRRNRKESGLNK-----------HSLSTQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETPDDIPQKKPARYRRAVSYDSKEY--------------YMRLA-------SGNPAIVQDAIVESSEGEAAQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEENQEQLQDQIAEGSSI--EEEEKTDN 2523          

HSP 2 Score: 1193.33 bits (3086), Expect = 0.000e+0
Identity = 571/1049 (54.43%), Postives = 740/1049 (70.54%), Query Frame = 2
Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDE----YDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRP----NMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+   ++  N  I  +      + ++++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STVV VW M  +  K               A  ++L+  L GH + VTC   + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT TGRS+QI+   MS M +WD  NV++TG +DGVVR W +E++QVP + +   A+  E Q    +      +   +SS+ E DE     D ++      S  ++ + A+  R+  A   D+    S    ++                S+  +DG   V  +   + ++ L   LS P   P    N  +L+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ S    RN
Sbjct: 2529 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNAGISVLP----GSTSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAMTVYECLSEWGQILCAICPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKTVTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIICCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPAEVLEMQEDCPEAQIGQEAQDEDSSDSEADEQSISQDPKDTPSQPSSTSHRPRAAS-CRATAAWCTDSGSDDSRRWSDQL---------------SLDEKDGFIFVNYSEG-QTRAHLQGPLSHPHPNPIEVRNYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGSEDGPRN 3525          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q6VNB8|WDFY3_MOUSE (WD repeat and FYVE domain-containing protein 3 OS=Mus musculus OX=10090 GN=Wdfy3 PE=1 SV=1)

HSP 1 Score: 1231.47 bits (3185), Expect = 0.000e+0
Identity = 883/2774 (31.83%), Postives = 1399/2774 (50.43%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKT-----------IVSDSSFIP----NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTY--------ISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYE------NPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENI------NCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFN 8068
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE                 AG       P    RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+    E  +D+++ L+ L+  LTT G  EL+P   ++    + + GF +P P  K  S+RN  AF VLQ+ FL A+T+FL   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+ +    + + +K  ++   H+ IFK+V +++G+LE+ VN LH YA  LK    A     DS NN    +Q  L LL+++ LT+L+   + N  +FR+ GG+ C  ++V + + +  AL  I+ L LS   E+DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E   S   K  W+ + + ++LE +  +   LT AL+ EP+N  +F   + Y  L +A+R LGCF SD+  I   N    N+Q +                +E +VS+    D++         L  CS+          +  ++Y  A + FD+            S       T            VS     P      +KL V  S + +  ++I+HP A+++++ L+ ++     Q  H ++LQ+ +   L  L   +RN Q+MCE+  +   LL     A+ +E+H LH     +FERLA+Q + P  +R+FLRLA PL C            +   S+  ++P   +       G G D  F ++         S ++   G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLP  +    ++  ++       +  ++ G+G GER FPP  G S+S W C++ FSS    HP+RLL++ R    S +   CL I ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HL L   R GM+K+S+ + +L+GQL+ T KL+Y+      S  +   ++++VYAY+GT P   +I++L WR GP HF+EE L  S V+ I  LGPNY+G+FQ    P  D +      +P+ SLVAEEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HNAAGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL   L  R + L       P    I+  LS L++    + N  +DL RFGQF+  TL      E  + +  NN+   +    +    L+    +  +  L  +   +   + E      +  EEL++ LGFDWI++FM+  +HP+TV  AMR LV LLS    ++KF++G+   GWL  TD VL  + G +L  N          +REIN D+CH PGF+ LQS LP H  +P +YF+L+AL L   +  +P+NL+ + P T           S    Q  QF+ +S+  F+FG                       G +++ I                  +C+E+A +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +  S+ +  DFL  L   ++P +           D  + S  ++   F+ ++ +  +++E C           + T   L + PA+K + DF +++I+D   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  ++I ++ +LI+Q ++R   ++ +++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G ++ G+        +TW+        PD   + +I +   Q+    +N         +W E+  +KKQ+LEE FK+      +   ++    P IE+  LK W +++  E    +     R    +P +  + S +++G  +S         KL    RN     L                         +  S +E   W+  HI+VV++L+D     + +++   + Y+  +W  +E EL RERGLWGP +GS LDKWML+  EGPCRMRKKM+ N+ FY HYPY P         E    V +  +++ A S D + YY               +L+       S NP  V++ I        + ++PE    +T + ++G          S P  GD +  ++ QD   +   I  +E+E+T N
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPE-----------------AGGGAQNELPL-AERRGLLQKAFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQGKEAEC-RDALKDLVSLVTSLTTYGVSELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNFLAQIILDAITNIYMADNANYFILESQHTLSQFAEKISKLP-EVQNKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYHCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPAQALNEQGDSRNNSSVEDQKHLALLVMEALTVLLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMTIQQLVLSPNGEDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRSRTVFRKVGGFVYITSLLVAMERSLSSPPKNGWEKVSQSQVLELLHTVFCTLTAALRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISAVNVFPSNTQPFQR------------LLEEGAVSV----DSV------SPTLRHCSK----------LFIYLYKVATDSFDSHAEQIPPCLTSESSLPSPWGTPALSRKRHAFHCVSTPPVYPAKNVTDLKLQVTSSPLQSSDAVIIHPGAMLAMLDLLASVG-SVTQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCGAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLASPLNCGAWDKKLLKQYRVHKPSSLSFEPEMRSSVITSLEGLGSDNVFSSHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLP--SLAPHNAPTNNTVTTGLTDGAVVSGMGSGERFFPPPSGLSYSCWFCIEHFSSPPNNHPVRLLTVVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGELVVEGQWHHLALLMSR-GMLKNSTAALYLDGQLVSTVKLHYVHSTPGGSGSANPPVLSTVYAYVGTPPAQRQIASLVWRLGPTHFLEEVLPPSSVTTIYELGPNYVGSFQAVCVPCKDAKSEGVTPSPV-SLVAEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLGISSHENATPVKLVHNAAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQ---GFPNS-NDLLRFGQFISSTLPTFAVCEKFVVMEINNEEKPDPGAEEEFGGLVSANLILLRNRLLDILLKLVYTSKEKTNINLQACEELVRTLGFDWIMMFMEEHLHPTTVTAAMRILVVLLSNQSILIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFLVLQSFLPKHTNVPALYFLLMALFLQQPVSELPENLQVSVPVT-----------SSRCKQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIH----------------NVCTESAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWLSPDFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAADTGMNRSQSEYCN----------VGTKTYLTNHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTHVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHAG-SVEGFGLEAEARMTTWHIMIPSDIEPDGGYSQDISEG-RQLLIKAVNR--------VWTELIHSKKQVLEELFKVSLPVNDRGHVDIALARPLIEEAGLKCWQNHLAHEKKCIS-----RGEALVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLHK-----------------------HSPSPQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIECELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYVP-------ETEQEASVGKPARYRRAISYDSKEYYL--------------RLA-------SGNPAIVQDAIVESSEGEATQQEPEHG-EDTIAKVKGLVKPPLKRSRSAPDGGDEETQEQLQDQIAESGSI--EEEEKTDN 2505          

HSP 2 Score: 1184.47 bits (3063), Expect = 0.000e+0
Identity = 566/1044 (54.21%), Postives = 736/1044 (70.50%), Query Frame = 2
Query: 8285 MIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWIL+DY+SE +DLT+P TFR L KPMGAQ++ RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+   ++  N  I     +   A ++++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STVV VW M  +  K               A  L+L+  L GH + VTC   + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT TGRS+QI+   MS M +WD  NV++TG +DGVVR W +E++QVP + +    +  E Q    +      +   +SS+ E +E    +  + + S  + +       S  A +    D  SD+         S++++ D        +DG   +N  E    + +Q  L      P    +  +L+ G+ W+RQL+FRSKLTMHTA++R DN +P+ +++L +S+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+YS+  ++ +    RN
Sbjct: 2511 LLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGIRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILSDYDSEEVDLTNPKTFRNLAKPMGAQTDERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLFNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNIGIS----VPPGATSDKIFFHHLDNLRPSLTPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAVCPNPKLVITGGTSTVVCVWEMGTSKEK---------------AKPLTLKQALLGHTDTVTCATASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEDLEMQEGCPEAQIGQQAQDDDSSDSETEEPSVSQDPKDTSSQPSSTSHRPRAASCRATATWCTDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQTRAHLQGPLAHPHPNPIEARSYSRLKPGYRWERQLVFRSKLTMHTAFDRKDNTHPAEVTALGVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRN 3507          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|E9Q2M9|WDFY4_MOUSE (WD repeat- and FYVE domain-containing protein 4 OS=Mus musculus OX=10090 GN=Wdfy4 PE=1 SV=2)

HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0
Identity = 347/815 (42.58%), Postives = 490/815 (60.12%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG----EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVS 10639
            + QV ++ ++   EK+        +QG  V EG+LLFGQ +FYI + FTL  T ++   ++   ++ +P +        FN   + + SD +S     + ++RE+ + R+LLQ IA+E+F  +G + LL F    ++K    F           Q S+ G+        G+T    N       ++++ QRW+K EISNF+YLMYLNTLAGR+YND MQYPVFPW+LADY SE L+LT+P TFR L KPMGAQ++ R  +F +R+++ +   G+ T   HY THYSSA+IVA YLVRM PFTQ F  LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N  + G  Q+G  LGD+ LPPWA GD R+FI  HR+ALE D+VS++L+ WIDLIFGYKQ G AAVEAVN FH  FY   +D+ SI DPL +S ++GFI+NFGQ+PKQ+F KPHP++          K  D   P+     ++  F H+L  + PS   VK++          K A+G I+  +              S+LAVE+NK L+PPL+ R  +WGF D S  +G+Y SDK++  +E    +G  +C +C +  +++T G S VV +W +S+   +P                 L L+  LYGH +AVTCL  + +++LLVSGS+DRTCI+WDL  +  +  L  H   ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G    I    +     WD  +V+ITG  DG+VR+W  E V++P+            QAV  +P  E +S
Sbjct: 2374 ERQVILQELL-DGEKVSQKVPMVIVQGHLVSEGILLFGQHHFYICENFTLSPTGDVYCTHHCLSNISDPFI--------FNMCSKDRSSDHYSCQRHAYSDLRELRQARFLLQDIALEIFFQNGYSKLLVFYNSDRSKALKSFSTF--------QPSLKGK--------GTTEDPFNLRKHPGFDRTMLQRWQKREISNFEYLMYLNTLAGRTYNDYMQYPVFPWVLADYTSEMLNLTNPKTFRDLSKPMGAQTKERKLKFTQRFKDVEKIEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCSLQGGSFDVADRMFHSVKSTWESASKENMSDVRELTPEFFYLPEFLTNCNAVEFGCMQDGTTLGDVQLPPWADGDPRKFISLHRQALESDFVSSNLHHWIDLIFGYKQQGPAAVEAVNTFHPYFYGDRIDLGSITDPLIKSTILGFISNFGQVPKQIFTKPHPSRNTTGKNPGPGK--DASTPVGLPGHSQS-FLHSLPALRPSQVTVKDMYLFSLGSESPKGAIGHIVPTE-------------KSILAVEKNKLLMPPLWNRTFSWGFDDFSCCLGSYGSDKILMTFENLAAWGPCLCAVCPSPTMIVTSGASAVVCIWELSLVKGRPR---------------GLKLRQALYGHTQAVTCLTASVTFSLLVSGSQDRTCILWDLDHLSRVACLPVHREGISAIAISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGTITCCCIVEGPAWDASHVIITGSKDGMVRIWKTEDVKMPVPR----------QAVMEEPSTEPLS 3122          

HSP 2 Score: 322.783 bits (826), Expect = 2.141e-86
Identity = 279/1011 (27.60%), Postives = 470/1011 (46.49%), Query Frame = 2
Query: 2690 IIVHPEAVISLIHLIPAIRC-DQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLA----DPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVF---GNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGS---LVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEP---LSKLIELIISYSNK------PDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGW----LTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKE 5647
            +I+HP  +  ++ L+P +   D  Q +   E+Q  +   L  L   ++N Q+MCE+  M   L+      +      LHS+ + +FE+L +Q + P  +R FL L          + + +     +    + +C        +      GS     ++ SQ         +L    SLI +T+ +N                      R A  PSFVE +M  EG+GCLF P+++    +S   S+   +              R FPP GG +FS W  + + +++   HP+R L+L R L  + +   C +IS+    +  ++VST+E+ F      E E+ +E ++   +    C  LL    W HL +   +  M ++ S + +L+GQ I + K+ YI     S F    +    VY YIGT     + S+L WR GP +  EE ++A  ++ I +LGP Y GNFQ   L  E+P G    L+AEE+V F LY  + SI ++  I   YNE+D  +IA+++++  ++ ++P+ ++ N AGHLSG  R+LGA+ +G  G+R F  +P    +D +GG  +LLG++++A D   +YA +K++ S L  N ++   L  H+ GY++++FLL+KK   L+ RIF L++ + G+A+  F+   +                 N  +F  V+C+  LW +        + L   +  H+ E  Q             R+ +      +L  LL L                      NEP   LSK+  +I     +        DL R G F+++TL     +E +I L+   +     A  + +   I +RN   +++  ++++S    T+E K  E++   LG DW LL +Q  +HPST  LA++ L+  LS P    +FRDG+    W    + G D+V         MDN + +PA   +     C LPGF  L   L +H  IP++Y ++ +  L   +  + +  +E
Sbjct:  826 MIMHPGIICIMVRLLPRLYLEDHPQLSE--EIQCSVARHLLSLVKSEKNRQVMCEA-GMLRTLMTFCPRTLSTGGSDLHSILIRIFEKLGSQAIEPDVLRQFLGLGIRPPRSAAVKSLHLPPGHEDNPGCSGSCAATAEKPTDSSPRPGGSQALRPSWASQYSA-----TALQTTLSLISMTSPRN------------------LQPQRAALTPSFVEFDMSSEGYGCLFTPTLSTVMGTSTEHSISGGTGSGAP---------RPFPPPGGLTFSCWFLISRQANVMEGHPLRFLTLVRHLARTEQPFVCFSISLCMD-DLSLVVSTEEKEFQPLDAMEPEDEAEPSAGRQLQVR-CSQLLTCGQWYHLAVVVSKE-MKRNCSVTTYLDGQAIGSAKMLYIQALPGSFFSMDPSSFVDVYGYIGTPRVWKQKSSLTWRLGPAYLFEEDISADTLALIIKLGPRYCGNFQAVHLQGEDPDGEATPLIAEERVSFGLYVPSSSITSIMNIRNTYNEVDSRLIAKEMNISSRDNATPVFLLRNCAGHLSGPLRTLGAVAVGQLGVRVFHSSPAASSLDYIGGPAILLGLISLATDDHTMYAAMKVLHSVLTSN-AMCDYLMQHICGYQILAFLLRKKTSFLNHRIFQLILSVAGTAELGFRPSAVT----------------NMCIFQHVLCNFELWTN------TADNLELTLFSHLLEILQS-------PREGPRNAEVAHQAQLLPKLLFL---------------------FNEPSLALSKVSTIIAILGCQLKGHFNIQDLLRVGLFVIYTLKPSSVNERQICLD-GAQDPSRPAGSQTSGKAIWLRNQLLEMLFGVISSSQLHLTSELK--EQVFLSLGPDWFLLLLQGHLHPSTTTLALKLLLYFLSSPPLRGRFRDGLSAGCWVENCMDGVDIV---------MDNLKSRPAVPDQ---SPCLLPGFRVLNDFLAYHVLIPEVYLIVSSFFLQTPLTELTNGPRE 1732          

HSP 3 Score: 157.918 bits (398), Expect = 1.763e-36
Identity = 162/684 (23.68%), Postives = 313/684 (45.76%), Query Frame = 2
Query:  272 FQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284
            F+ +      VS  + +EI++    +  E+A  A  Q LQ        + +  G +LL  + +L+   +  +  ++ + LP+  ++CLY+FF  P          + D +      G +                  F Q+L  IC      E L+   +L+ L   +A+ C   +S   W++    VL+ I+    S S IQ++     +   ++N++K    L + E+ +    + + +R+S  ++  LL +F N +GY ++ + L++         E   +  LI L+  LTTCG  EL+    +   + YP +EGF+     +   +++N  AF VLQ++F  A    LC+++L AIKT++  +P N+F+LE        F+E +  K   VQE    L++ +V  L YVP + ++ +  ++K  +    T + +++ +R+   +++F ++ +D G+L + + QL   A  ++K  +   S  V + + EL  +++  +  L+    +N  + +  G       +V F+K        +  +L  ++ L++ + +EE MS  +G + S ++Q        L    + + E+ +    FR    F   +  L  LEG   +        +   + LE V   L +++ AL  +P N  +F  N  +  L E +  LGCFG+
Sbjct:   89 FRSLQRLAEDVSDQLAQEIQQALAGKPAEQARAAAGQLLQ-----WKSDADQDGNLLLKSVYVLTGTDSETLGRVVDSGLPALLLQCLYLFFAFP---------VEKDDLLESDVQGQRM-----------------FVQMLLNICSESQGLEGLLSGSELQSLL--IATTCLREHSCLFWKQPTFCVLRAIS-KAQSPSVIQYLRTADCVRLSVQNLSKLADTLPAPEVSEAVSLILNFVRDSYPISSALLLEFENGEGYPLLLKVLLRYNGLTQGVVE-PHLEELIELVMWLTTCGRSELK----VFDSVTYPQLEGFKFHQEAS-GVTVKNLQAFQVLQNLFHRASDSVLCIQVLLAIKTMWAWNPRNFFLLEWTLQPISQFAEIIPLKPTPVQEHFFQLLETLVFKLLYVPHEVLAKVQRLIKESSELSCTLVALRSILRITASDRLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKECSPDVQDPERELTYVMLSTVVTLLQGSVRNAVVLKDHG-------MVPFIKIFLDDECYRGPSLSILEQLSVIN-AEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILETPKGHAAFRVSSGFNGLLSLLSDLEGSLQVPEVTTCGAVSPSQTLELVLHTLCVVSAALHLDPVNEHFFRSNGLFEKLAEDLCLLGCFGT 723          

HSP 4 Score: 61.6178 bits (148), Expect = 2.113e-7
Identity = 62/279 (22.22%), Postives = 120/279 (43.01%), Query Frame = 2
Query: 5900 MCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHV-IDIILECDIENTTQEHMKQFQTVFMNSLTEHFM-----AVDILSGQNLPLPPGGSYANIPN--NIYYFFSRVVDKVWQENYVDDPDVIISYLCRLI-----SQGRKRQITQESLYRSFNRLILFRLSR 6697
            +C E A +LL M++ ++NQ      + +  W +  P ++L+ F+ L H +    S     DFL  +    +P       +S    N  SP +     +   G               S    PA + + +F ++++ +      N  Q + +++ILE   +  T +  + FQT  + S  + F       +  L G   PLP   + A +P+  ++ YF  ++V+K++   +  DP  I+ ++   I     +   ++     +LY S N++IL  LS+
Sbjct: 1755 LCIEGALLLLGMLKAIMNQ--PPAGSGDGAWEQTLPSSVLQ-FLRLVHRSYPQDSAWRTPDFLQTVAIITFPLETQKETTSESSRNTSSPGASAEASHAAEG------------FQASFQPHPALRQLREFMQVLLRELLLGGSNPKQWLPLEVILEASPDGATSQQKRDFQTEVLLSTMDIFQVPSGDGMPTLRGSKEPLPNAEAGA-VPSLASVSYFTQKLVEKIYSGVFSADPRHILLFITEHIIAVIENPSSQKDTVMSALYSSLNKVILHCLSK 2017          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q6ZS81|WDFY4_HUMAN (WD repeat- and FYVE domain-containing protein 4 OS=Homo sapiens OX=9606 GN=WDFY4 PE=1 SV=3)

HSP 1 Score: 642.114 bits (1655), Expect = 0.000e+0
Identity = 335/788 (42.51%), Postives = 479/788 (60.79%), Query Frame = 2
Query: 8261 DNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFN--HRRKMSDKFS-----FGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMG-EKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGE-TPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQID-PMAPLASSAPAERLFYHNLDNMEPSLQPVKEL----------KNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPI 10564
            + QV ++ ++   EK+   F    +QG  V EG+LLFG  +FYI + FTL  T ++    +   ++ +P +        FN   + + +D +S     + ++RE+ + R+LLQ IA+E+F  +G +  L F    ++K +  F     SL               K  +  T     + G ++ + Q+W+K +ISNF+YLMYLNT AGR+ ND MQYPVFPW+LADY SETL+L +P  FR L KPMGAQ++ R  +F +R++E +   G+ T   HY THYSSA+IVA YLVRM PFTQ F  LQGG FD+ADRMFHS+K TWESAS+ NM+D++EL PEFFYLP FL N N  + G  Q+G VLGD+ LPPWA GD R+FI  HR+ALE D+VSA+L+ WIDLIFGYKQ G AAV+AVN+FH  FY   +D+ SI DPL +S ++GF++NFGQ+PKQLF KPHP  R      +  K +  P++      P    F+++L ++ PS   VK++          K A+G I+             S   ++LAVE+NK L+PPL+ R  +WGF D S  +G+Y SDK++  +E    +G  +C +C +   ++T G STVV VW +S+   +P                 L L+  LYGH +AVTCLA + +++LLVSGS+D TCI+WDL  + ++ +L  H   ++AI IS+V+G + SCAG +L LW+++G+ LAS+ TA G    I    +     WD   ++ITG  DG+VR+W  E V++ +
Sbjct: 2376 ERQVILQELL-DKEKVTQKFSLVIVQGHLVSEGVLLFGHQHFYICENFTLSPTGDVYCTRHCLSNISDPFI--------FNLCSKDRSTDHYSCQCHSYADMRELRQARFLLQDIALEIFFHNGYSKFLVFYNNDRSKAFKSFCSFQPSL-------------KGKATSEDTLSLRRYPGSDRIMLQKWQKRDISNFEYLMYLNTAAGRTCNDYMQYPVFPWVLADYTSETLNLANPKIFRDLSKPMGAQTKERKLKFIQRFKEVEKTEGDMTVQCHYYTHYSSAIIVASYLVRMPPFTQAFCALQGGSFDVADRMFHSVKSTWESASRENMSDVRELTPEFFYLPEFLTNCNGVEFGCMQDGTVLGDVQLPPWADGDPRKFISLHRKALESDFVSANLHHWIDLIFGYKQQGPAAVDAVNIFHPYFYGDRMDLSSITDPLIKSTILGFVSNFGQVPKQLFTKPHPA-RTAAGKPLPGKDVSTPVSLPGHPQP----FFYSLQSLRPSQVTVKDMYLFSLGSESPKGAIGHIV-------------STEKTILAVERNKVLLPPLWNRTFSWGFDDFSCCLGSYGSDKVLMTFENLAAWGRCLCAVCPSPTTIVTSGTSTVVCVWELSMTKGRPR---------------GLRLRQALYGHTQAVTCLAASVTFSLLVSGSQDCTCILWDLDHLTHVTRLPAHREGISAITISDVSGTIVSCAGAHLSLWNVNGQPLASITTAWGPEGAITCCCLMEGPAWDTSQIIITGSQDGMVRVWKTEDVKMSV 3108          

HSP 2 Score: 325.094 bits (832), Expect = 3.576e-87
Identity = 273/1007 (27.11%), Postives = 475/1007 (47.17%), Query Frame = 2
Query: 2687 SIIVHPEAVISLIHLIPAI-RCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISL----TRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHV-ILVSTKEEVFGNRE--QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMG-TLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPIL---DYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHL-GYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINP--LNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWL----TGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKET 5650
            + I+HP  V  ++ L+P +   D  Q +   E+Q  +   +  L   ++N Q+MCE+  +   L+     A++    PLHS  + +FE+LA+Q + P  +R FL L  P      T   D  +T      C                SG      +++   P      L    T+    +G +     + +  + +I+  T   +    R A  PSFVE +M  EG+GCLF+P+++    +S   SV                  R FPP GG +FS W  + +  +    HP+R L+L R L  + +   C ++S+   P+ + ++VST+E+ F   +  +       S+    +  C  LL    W HL +   +  M +H + S  L+GQ+I + K+ YI   +   F SM  +    VY YI T     + S+L WR GP +  EE ++   +  I +LGP Y GNFQ   +   D ++     VAEE+V F L+  + SI ++  I   YNE+D  +IA+++++  ++ + P+ ++ N AGHLSG+ R++GA+ +G  G+R F  +P    +D +GG  +LLG++++A D   +YA VK++ S L  N ++   L  H+ GY++++FLL+KK  LL+ RIF L++ + G+ +  F+   I                 N  +F  ++C+  LW++        + L  ++  H+ E  Q   +    ++++ +                  L+ ++I L  + ++ P  ++TII      ++   +       DL R G F+V+TL     +E +I ++      L +   + +   I +RN   +++L ++++     ++E K  EE+   LG DW LL +Q  +H ST VLA++ L+  L+ P    +FRDG+    W+     G D+V         MDN + Q     +     C LPGF  L   L HH  IP++Y ++    L   +  + D  K++
Sbjct:  826 AAIMHPGVVCIMVRLLPRLYHEDHPQLSE--EIQCSLASHIQSLVKSEKNRQVMCEA-GLLGTLMASCHRALVTSGSPLHSRLIRIFEKLASQAIEPDVLRQFLGLGIPSSLSATTKILDSSHTHRGNPGC----------------SGSQTAQGLAEGPWPAAPDAGLHPGVTQAPQPLGESQDSTTALQTALSLIS-MTSPRNLQPQRAALAPSFVEFDMSVEGYGCLFIPTLSTVMGTSTEYSVSGGIGTGAT---------RPFPPPGGLTFSCWFLISRHGAATEGHPLRFLTLVRHLARTEQPFVCFSVSLC--PDDLSLVVSTEEKEFQPLDVMEPEDDSEPSAGCQLQVRCGQLLACGQWHHLAVVVTKE-MKRHCTVSTCLDGQVIGSAKMLYIQ-ALPGPFLSMDPSAFVDVYGYIATPRVWKQKSSLIWRLGPTYLFEEAISMETLEVINKLGPRYCGNFQAVHVQGEDLDSEATPFVAEERVSFGLHIASSSITSVADIRNAYNEVDSRLIAKEMNISSRDNAMPVFLLRNCAGHLSGSLRTIGAVAVGQLGVRVFHSSPAASSLDFIGGPAILLGLISLATDDHTMYAAVKVLHSVLTSN-AMCDFLMQHICGYQIMAFLLRKKASLLNHRIFQLILSVAGTVELGFRSSAIT----------------NTGVFQHILCNFELWMN------TADNLELSLFSHLLEILQSPREGPRNAEAAHQA----------------QLIPKLIFLFNEPSLIPSKISTIIG-----ILACQLRGHFSTQDLLRIGLFVVYTLKPSSVNERQICMDGALDPSLPAGS-QTSGKTIWLRNQLLEMLLSVISSPQLHLSSESK--EEMFLKLGPDWFLLLLQGHLHASTTVLALKLLLYFLASPSLRTRFRDGLCAGSWVERSTEGVDIV---------MDNLKSQSPLPEQ---SPCLLPGFRVLNDFLAHHVHIPEVYLIVSTFFLQTPLTELMDGPKDS 1740          

HSP 3 Score: 139.043 bits (349), Expect = 7.400e-31
Identity = 158/677 (23.34%), Postives = 312/677 (46.09%), Query Frame = 2
Query:  302 VSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSG--WRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTK--GGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYP-IEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILE-PQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVK-------SQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPP---WDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGS 2284
            VS  + ++++K    +  E+A LA  Q L         + +  G++LL  + +L+   +  +  +  + LP+  ++CLY+FF  P   ++ ++  + D                   V +       F Q+L  IC      E L+   +L+ L   +A+ C   +S   W++    VL+ I+    + S IQ++     +   L+N+++    L + E+ +    +   +++S  V+  L  +F NS+GY ++ + L++ +    +E +   +  L+ L+  LTTCG  EL+    +   I YP +EGF+     +   +++N  AF VLQ+VF  A    LC+++L  I+T++  +  N+F+LE        F E +  K   VQE    L++ +V  L+YVP + +  +  ++K       T + +++ + +   + +F ++ +D G+L + + QL   A  ++K  +   +  V + + EL  +++  +  L+    +N  + +  G       +V F+K        +  +L  ++ L+ +  +EE MS  +G + S ++Q        L    + +  + + R  FR    F   +  L  LEG    + +PP   W  +  ++ LE V   L  ++ AL  +P N  +F  N  +  L E +  LGCFG+
Sbjct:   99 VSDQLAQQLQKALVGKPAEQARLAAGQLLW-----WKGDVDQDGYLLLKSVYVLTGTDSETLGRVAESGLPALLLQCLYLFFVFP---LDKDELLESD-----------------LQVQKM------FVQMLLNICSDSQGLEGLLSGSELQSLL--IATTCLREHSCCFWKEPTFCVLRAIS-KAQNLSIIQYLQATDCVRLSLQNLSRLTDTLPAPEVSEAVSLILGFVKDSYPVSSALFLEFENSEGYPLLLKVLLRYDGLTQSEVD-PHLEELLGLVVWLTTCGRSELK----VFDSITYPQLEGFKFHHEAS-GVTVKNLQAFQVLQNVFHKASDSVLCIQVLSVIRTMWAWNARNFFLLEWTLQPISQFVEIMPLKPAPVQEHFFQLLEALVFELHYVPHEILRKVQHLIKESPGPSCTLMALQSILSIAGGDPLFTDIFRDSGLLGLLLAQLRKQAKIMRKSGNKVSTPGVQDPERELTCVMLRIVVTLLKGSVRNAVVLKDHG-------MVPFIKIFLDDECYREASLSILEQLS-AINAEEYMSIIVGALCS-STQGELQLKLDLLKSLLRILVTPKGRAAFRVSSGFNGLLSLLSDLEGS---LQEPPLQAWGAVSPRQTLELVLYTLCAVSAALHWDPVNGYFFRRNGLFEKLAEDLCLLGCFGA 723          

HSP 4 Score: 67.0106 bits (162), Expect = 4.474e-9
Identity = 101/460 (21.96%), Postives = 198/460 (43.04%), Query Frame = 2
Query: 5900 MCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSL----PARKLIMDFFKMIIVDYFSLPKNSYQHV-IDIILECDIENTTQEHMKQFQTVFMNSLTEHFM------AVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLI-----SQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLK-LNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQIC-------LKTWNSYIESENIGTAS----SHWGRISL 7171
            +C+E A +LL M++  ++Q      +E+  W + +P ++L+F + L H            +FL  L  A +P        +    N  SPE+    ++                T+E L +     PAR+ + +F ++++ +      +  Q + ++++LE   ++ T +  + FQ+  + S  E F       A     G+        + A    NI  F  ++V+K++   +  DP  I+ ++   I     +   +R     +LY S N++IL+ LS+       ++ + + L  L       ++   +F   NS+  F++CL+H L+ L       G+        ST++       +++K+    +  L  +   I+   ++LWQ++   ++Q LE+AFKI LS         IE++        LK W  Y+ SE    AS    +H  +++L
Sbjct: 1762 LCTEGALLLLEMLKATMSQPL--AGSEDGAWAQTFPASVLQF-LSLVHRTYPQDPAWRAPEFLQTLAIAAFPLGAQKGVGAESTRNTSSPEAAAEGDS----------------TVEGLQAPTKAHPARRKLREFTQLLLRELLLGASSPKQWLPLEVLLEASPDHATSQQKRDFQSEVLLSAMELFHMTSGGDAAMFRDGKEPQPSAEAAAAPSLANISCFTQKLVEKLYSGMFSADPRHILLFILEHIMVVIETASSQRDTVLSTLYSSLNKVILYCLSK------PQQSLSECLGLLSILGFLQEHWDVVFATYNSNISFLLCLMHCLLLLNERSYPEGFGLEPKPRMSTYHQVFLSPNEDVKEKREDLPSLSDVQHNIQKTVQTLWQQLVAQRQQTLEDAFKIDLSVKPGEREVKIEEVTPLWEETMLKAWQHYLASEKKSLASRSNVAHHSKVTL 2196          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Match: sp|Q55DM1|LVSA_DICDI (BEACH domain-containing protein lvsA OS=Dictyostelium discoideum OX=44689 GN=lvsA PE=4 SV=2)

HSP 1 Score: 570.466 bits (1469), Expect = 1.066e-161
Identity = 308/775 (39.74%), Postives = 444/775 (57.29%), Query Frame = 2
Query: 8315 MFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAF-PKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSI------------------FSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDP-----SGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPY-GDIMCVLCLNE-RILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVP 10561
            M+ C  + G+D  EG+L+F   Y YI DG+   K     +I+ +   ++   +P    +           K+++ +IR+V KRRYLL+ +A+E+F  DGRN L+ +  +  ++++Y   +   SS      ++I G  Q   I  G T                    F++   +  +T +W++G+ISNFQYLM+LNTLAGRSYNDL QYPVFPW+L+DYESE LD+  P  +R L KPMGA  E+R  +F +R+  WDD        + P +HYGTHYSSA IV +YL+R+EPFTQHFLKLQGG +D  DR+F SI + W S+SQ +   + ELIPEF+YL  FL N NKF+ G KQ G  + DI+LPPWAKG  +EFI+ HR+ALE DYVS HL+EWIDLIFGY+Q G AA +++NVF++L YEG V+I +I DP++++A I  INNFGQ PKQLF KPHP +                A L       +    N          +K++   VGQI    L    +  VG           NK L+PP +++Y+ WG  DGS+R   Y++   IKV E  D + G + C+    + RI ++GG  +++ V+N+                         SL   L GH  ++TC++ +  Y+++VSGS DRTCI+WDL R+CY+R L  H  P++ I I + TG +  C+GT + +++++GE L +  T+   + QI     S   +W   NV++TG  DG V++W LE   +P
Sbjct: 2815 MYNCGSVDGMDKIEGILIFCPVYMYIFDGY--YKDENTGDISEVEEKINSEWLPEGTVLPMKKKIIHYFLKWAYEDIRDVLKRRYLLRQVALEIFSTDGRNNLVVYRDEPTRDEVYHTLVNNVSS-----HNTIGGDAQG--ITGGQTGNDDNDDHHGGGGGRGVRDRFTSIWRKSPLTLKWQQGQISNFQYLMHLNTLAGRSYNDLTQYPVFPWVLSDYESEELDIDDPKVYRDLSKPMGALEESRAQKFRERFENWDDQEPNEHGHKVPKFHYGTHYSSAAIVLYYLIRLEPFTQHFLKLQGGRWDQPDRLFSSITEAWASSSQGSTGVVMELIPEFYYLDEFLVNNNKFNFGTKQGGEPIDDIILPPWAKGSPQEFIKLHRKALESDYVSEHLHEWIDLIFGYRQQGKAADDSLNVFYYLTYEGAVNIDAISDPVEKAATIAQINNFGQTPKQLFDKPHPKRN---------------ATLMGLPFYAKALTGNF---------IKDIGEPVGQI---RLINDRATCVGF----------NKVLLPPNHSKYMLWGLPDGSIR---YNTGDKIKVLE--DHHDGPLTCLTATEDGRICVSGGSDSLICVYNLK----------------------RFSLAKRLSGHTGSITCVSASRPYSIIVSGSDDRTCIIWDLNRLCYVRSLDAHEGPISCIGIHDTTGEIVVCSGTTISVYTVNGELLINYKTSQIANDQITCCIWSKGPEWLGENVLLTGHRDGKVKVWGLETRLLP 3516          

HSP 2 Score: 87.8113 bits (216), Expect = 2.736e-15
Identity = 114/535 (21.31%), Postives = 238/535 (44.49%), Query Frame = 2
Query:  113 TDSSLNQLKILFADY-KTKISNSEISDHDQLLYDIIPLFH--KIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQ------NSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYP---ATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIE-IVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPM---------NKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISV 1651
            + ++  +LK+L+ ++  +K    ++   ++LL   I L+   KI   +P +++       F+F   +S  +V++I +      + +      Q ++  + +      ++ + +  G+ LL  + ILS       E M  AS+PS  V+CL  FF +P           + +M   T                + I+ +   ++++ +CF     +  EEL + + L  LF  +++ CP  +   R         +    L   TI +I  K++I+  +K++T   + + E  V +   +  +L ESS  + +LLD+F+ + GY      +  L +  S++ +      L+  I  L   GY       N+S+    P+E   +P            N+N   +N  AF VL+  FL +  +   ++IL+ I ++Y  +  N+ +L+  +T   F ++    S  ++  ++ ++  +V  LN VP +E+S+ S+++       T  ++ +    L+     +K + ++ G+L+I V
Sbjct:  143 SQATAQKLKLLWQEFLSSKSDKDKVMRLNKLLPYFIGLYEDKKIDTKSPMVDIFGNNSKSFSFA--ISRRLVKDINEIMKQANSPQQPPQPPQLIKETIAKEIYKFFSTTSGQVSGFELLYSIEILSESNTSCAEAMAEASIPSMLVRCLQYFFLVP-----------YTTMMETT----------------KGIIEE---KLIRTLCFLSKQKSAIEELQKTDTLSTLFALMSNECPPSHRPLRAKIGSF--GLELTDLYPPTITYINSKRVIANIIKDLTNYYMFTPESYVTLCRIIIKILSESSKKSTILLDEFQRNDGYT---FLVDSLFRLESSKDKPALFEQLLDSICSLVYIGY------GNVSL----PVENSSVPYQTSINNIKEISNQNYISKNGNAFKVLERYFLKSNYEENRVKILDRILSVYSSNTVNFILLQHTSTLTKFIQEYESLSNGLKYHVMKIVCFVVTVLNCVPFQELSTFSLLVGENPSFYTLEMINQLITTLVNFEFRYKHIFRETGLLDILV 630          

HSP 3 Score: 74.7146 bits (182), Expect = 2.141e-11
Identity = 37/88 (42.05%), Postives = 52/88 (59.09%), Query Frame = 2
Query: 7502 KWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELY 7765
            +W+++ +++ RER +WGP     LDKW LDS EGP RMRKKM  N  FY++YPY P    P  + +N+  +       +  SAD E Y
Sbjct: 2486 QWENMRAQITRERAVWGPSEPHPLDKWKLDSTEGPYRMRKKMEKNYNFYKNYPYVP----PSFDEQNNSLL------PIPCSADSETY 2563          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: A0A5G3JJ76 (WD repeat and FYVE domain containing 3 OS=Xenopus tropicalis OX=8364 GN=wdfy3 PE=4 SV=1)

HSP 1 Score: 2425.59 bits (6285), Expect = 0.000e+0
Identity = 1469/3872 (37.94%), Postives = 2167/3872 (55.97%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLE-SAEFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQP-GFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F ++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL V+ +L+      ++CM T S+PST +KCLY+FFDLP+ P+I    + +                  P    RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+   NE+ +D+++  + LI  LTT G  EL+P   L+    + + GF +P P  K  S+RN  AF+VLQ+ FL A+T +L   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+      +    K  ++ I H+ IFK+V K++G+LE+ VN LH YA  LK       EQ    ++    EQ +L L++++ LT+L+   + N  +FR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L IVL+ESHR R VFRKV  FV     LV +E   S   +  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +AIR LGCF           S  +   N   S+NQ F+   L  D +  + V                 +L  CS+          +  ++Y  A + FD                 H    + + S   P   + MKL    S+++   ++I+HP A++S++ L+ ++  D +Q  H ++LQ+ I   L  L   +RN Q+MCE+  +   LL+    A+ NE+HPLH     +FERLA+Q + P  +R+FLRL DPL C                S+  Y+P   +   +   G G D  FC       R N        G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLPS+AP +  +  +    +         G G   R+FPP  G ++STW C++  SS    HP+RLL+L R    S +   CLNI ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL+ T KL+Y+      S  +   ++++VYAYIGT P   ++S L WR GP HF+EE LTA+ V  I  LGPNY+G+FQ    P  D ++  GSL     V EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HN+AGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ L KKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R         D  L+ +++  +   +++ P    I+  LS L++   S     +DL RFGQF+  TL      E  + +  NN+  LE   +F   +   LI +RN    ++LK+L  S    T   +  EEL+K LGFDW ++FM+  +H +TV  AMR LV LLS P  +L+F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQSLLP H  +P +YF+L+ L L   +  +P+NL+ + P            IS  +N+S QF+ +S+  F+FG            +SG+ +++                            +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +   + +  +FL  L  +++P +           D  + S  ++   F+ +S +  +++E C           M T   L + PA+K + DF ++++++   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GG+Y  + NN++YF  RVVDK+WQ  +  D  +++  + +LISQ ++R   ++ E++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G N  G+        +TW+   P  I  D +  + ++ + L L    R     +W E+  +KKQ+LE+ FK+      +   ++ ++ P IE+  L+ W +++  E   T+          +P S  + S +++G  +S         KL    RN     L+                        +++S +E   W+  HI+VV++L+D     + +++   + Y+  +W   E EL RERGLWGP +GS LDKWML+  EGPCRMRKK++ N+ FY HYPY P       + E+     +  +++ A S D +              D Y +L P    N +    TVEE+ +   ++ +PE    +T + ++G            P+K      D  +D           E++E      M  D +        +E +S  E        ++ +DS+ ++                             ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY++DGFT+  TREI +I  +P+++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+      IN  +  M+ L      +++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STV+ VW    +  K               A +L+L+  L GH + VTCL  + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT  GRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP + +   AD  E P     +  G E+       S+ E+    Q+   + S+   N S     + +   ++  + D  SD+         S++++ D        +DG   V  + N SKVQ   ++S    SQ  +R +  KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ +    RN
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENEL-----------------PL-AERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDR----------------HVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPDDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENLQVSAPV-----------ISSRSNRSCQFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIP-------DAEHETNTMKPARYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGQEAQDDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3479          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: A0A5G3HUJ1 (WD repeat and FYVE domain containing 3 OS=Xenopus tropicalis OX=8364 GN=wdfy3 PE=4 SV=1)

HSP 1 Score: 2419.81 bits (6270), Expect = 0.000e+0
Identity = 1477/3892 (37.95%), Postives = 2175/3892 (55.88%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFD-----------NXXXXXXXXXXXXXXXXHYLKTIVSDSSF-IP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRP--YHRS---PCDNNENHCQ-VYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQP-GFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F ++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL V+ +L+      ++CM T S+PST +KCLY+FFDLP+ P+I    + +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+   NE+ +D+++  + LI  LTT G  EL+P   L+    + + GF +P P  K  S+RN  AF+VLQ+ FL A+T +L   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+      +    K  ++ I H+ IFK+V K++G+LE+ VN LH YA  LK       EQ    ++    EQ +L L++++ LT+L+   + N  +FR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L IVL+ESHR R VFRKV  FV     LV +E   S   +  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +AIR LGCF           S  +   N   S+NQ F+   L  D +  + V                 +L  CS+          +  ++Y  A + FD           N   L           K ++   VS SS   P   + MKL    S+++   ++I+HP A++S++ L+ ++  D +Q  H ++LQ+ I   L  L   +RN Q+MCE+  +   LL+    A+ NE+HPLH     +FERLA+Q + P  +R+FLRL DPL C                S+  Y+P   +   +   G G D  FC       R N        G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLPS+AP +  +  +    +         G G   R+FPP  G ++STW C++  SS    HP+RLL+L R    S +   CLNI ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL+ T KL+Y+      S  +   ++++VYAYIGT P   ++S L WR GP HF+EE LTA+ V  I  LGPNY+G+FQ    P  D ++  GSL     V EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HN+AGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ L KKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R         D  L+ +++  +   +++ P    I+  LS L++   S     +DL RFGQF+  TL      E  + +  NN+  LE     +F   +   LI +RN    ++LK+L  S    T   +  EEL+K LGFDW ++FM+  +H +TV  AMR LV LLS P  +L+F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQSLLP H  +P +YF+L+ L L   +  +P+NL+ + P            IS  +N+S QF+ +S+  F+FG            +SG+ +++                            +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +   + +  +FL  L  +++P +           D  + S  ++   F+ +S +  +++E C           M T   L + PA+K + DF ++++++   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GG+Y  + NN++YF  RVVDK+WQ  +  D  +++  + +LISQ ++R   ++ E++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G N  G+        +TW+   P  I  D +  + ++ + L L    R     +W E+  +KKQ+LE+ FK+      +   ++ ++ P IE+  L+ W +++  E   T+          +P S  + S +++G  +S         KL    RN     L+                        +++S +E   W+  HI+VV++L+D     + +++   + Y+  +W   E EL RERGLWGP +GS LDKWML+  EGPCRMRKK++ N+ FY HYPY P   H +    C N    C+ + Q  +++ A S D +              D Y +L P    N +    TVEE+ +   ++ +PE    +T + ++G            P+K      D  +D           E++E      M  D +        +E +S  E        ++ +DS+ ++                             ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY++DGFT+  TREI +I  +P+++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+      IN  +  M+ L      +++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STV+ VW    +  K               A +L+L+  L GH + VTCL  + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT  GRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP + +   AD  E P     +  G E+       S+ E+    Q+   + S+   N S     + +   ++  + D  SD+         S++++ D        +DG   V  + N SKVQ   ++S    SQ  +R +  KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ +    RN
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENELP------------------LAERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDSRAEQIPPCLTNETSLPSPWGTPAVSRKRHVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPGADDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENLQVSAPV-----------ISSRSNRSCQFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIPDAEHETNTMVCFNKICSCKCIGQKSRYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGQEAQDDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3522          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: A0A5G3JJY3 (WD repeat and FYVE domain containing 3 OS=Xenopus tropicalis OX=8364 GN=wdfy3 PE=4 SV=1)

HSP 1 Score: 2410.18 bits (6245), Expect = 0.000e+0
Identity = 1466/3884 (37.74%), Postives = 2159/3884 (55.59%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKK------EQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNW--SSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFD-----------NXXXXXXXXXXXXXXXXHYLKTIVSDSSF-IP---NPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD--FCTYISQMQRPN--------GGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQ---NPILDYENPIGSL-----VAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNIN-PLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKNTIY--LIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENIN--CSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-PQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERA-NNSKVQSTLLKS---LSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*ICKRN 11407
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F ++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL V+ +L+      ++CM T S+PST +KCLY+FFDLP+ P+I    + +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ ++ C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+   NE+ +D+++  + LI  LTT G  EL+P   L+    + + GF +P P  K  S+RN  AF+VLQ+ FL A+T +L   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+      +    K  ++ I H+ IFK+V K++G+LE+ VN LH YA  LK       EQ    ++    EQ +L L++++ LT+L+   + N  +FR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L IVL+ESHR R VFRKV  FV     LV +E   S   +  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +AIR LGCF           S  +   N   S+NQ F+   L  D +  + V                 +L  CS+          +  ++Y  A + FD           N   L           K ++   VS SS   P   + MKL    S+++   ++I+HP A++S++ L+ ++  D +Q  H ++LQ+ I   L  L   +RN Q+MCE+  +   LL+    A+ NE+HPLH     +FERLA+Q + P  +R+FLRL DPL C                S+  Y+P   +   +   G G D  FC       R N        G  + LTRVK L+ +TT                    D      +  P+FVE +   EGFGCLFLPS+AP +  +  +    +         G G   R+FPP  G ++STW C++  SS    HP+RLL+L R    S +   CLNI ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL+ T KL+Y+      S  +   ++++VYAYIGT P   ++S L WR GP HF+EE LTA+ V  I  LGPNY+G+FQ    P  D ++  GSL     V EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HN+AGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ L KKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R         D  L+ +++  +   +++ P    I+  LS L++   S     +DL RFGQF+  TL      E  + +  NN+  LE     +F   +   LI +RN    ++LK+L  S    T   +  EEL+K LGFDW ++FM+  +H +TV  AMR LV LLS P  +L+F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQSLLP H  +P +YF+L+ L L   +  +P+NL                         QF+ +S+  F+FG            +SG+ +++                            +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +   + +  +FL  L  +++P +           D  + S  ++   F+ +S +  +++E C           M T   L + PA+K + DF ++++++   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GG+Y  + NN++YF  RVVDK+WQ  +  D  +++  + +LISQ ++R   ++ E++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G N  G+        +TW+   P  I  D +  + ++ + L L    R     +W E+  +KKQ+LE+ FK+      +   ++ ++ P IE+  L+ W +++  E   T+          +P S  + S +++G  +S         KL    RN     L+                        +++S +E   W+  HI+VV++L+D     + +++   + Y+  +W   E EL RERGLWGP +GS LDKWML+  EGPCRMRKK++ N+ FY HYPY P       + E+     +  +++ A S D +              D Y +L P    N +    TVEE+ +   ++ +PE    +T + ++G            P+K      D  +D           E++E      M  D +        +E +S  E        ++ +DS+ ++                             ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY++DGFT+  TREI +I  +P+++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILAD++SE LDLTSP TFR L KPMGAQ+E+RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECDYVS+HL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+      IN  +  M+ L      +++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STV+ VW    +  K               A +L+L+  L GH + VTCL  + +Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT  GRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP + +   AD  E P     +            S+ E+    Q+   + S+   N S     + +   ++  + D  SD+         S++++ D        +DG   V  + N SKVQ   ++S    SQ  +R +  KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ +++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ +    RN
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPARHMTQKEQEEKLYMMLPVFIRVFGSAPSNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----ETSRGWMLLTVINLLASSGQKTVDCMTTMSVPSTLIKCLYLFFDLPHLPDIPGGAENELP------------------LAERRALLQKVFVQILVKLCHFVSPAEELAQKDDLQLLFSAITSWCPPYNIPWRKSAGEVLMTISRHGLSLNVVKYIHEKECLATCVQNMQQSNDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRICQGYVFLSDLLLRLEQAKENES-KDALKDFVNLITSLTTYGVNELKPA-GLTTGAPFLLPGFAVPQPTGKGLSMRNIQAFSVLQNTFLKAKTSYLAQIILDAIMNIYMSDNANYFILESQHTLSQFAEKITKLP-DVQVKYFEMLEFVVFSLNYIPCKELISVSILLKSSASFSCSIFATKTLLKFIRHHNIFKDVFKEVGLLEVMVNLLHKYAAVLKDPAQAYIEQGCASANRSTEEQRQLALVVMETLTVLLHGSNTNAGVFREFGGARCVHNIVKYPQCREYALMVIQQLMLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLIVLRESHRTRTVFRKVGGFVYVTSLLVAMEKALSCPPRNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAIRLLGCFF---------ESRKIRPSNILPSNNQPFH-RLLEDDVAQLDFVC---------------PVLKHCSK----------LFVYLYKVATDSFDSRAEQIPPCLTNETSLPSPWGTPAVSRKRHVYHAVSTSSLNAPKNLSDMKLHTGTSALSGSDAVIIHPGAMLSMLDLLASVDSD-SQPEHALDLQLAIANILQSLVHTERNQQVMCEA-GLHARLLHRCSAALANEDHPLHPPLQRMFERLASQALEPMVLREFLRLGDPLNCAAWDKRLLKQYRTHKPSSLSYEPEMRSSMIMSTEGIGSDSVFCVSEDSHYRINRSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTSNAVTTGLVDGAVLSGIGTGE--RLFPPPSGLTYSTWFCIEHLSSPPNNHPVRLLTLVRRANSSEQHFVCLNI-VLSAKDKSLIVSTKEELLQNYVDDFSEEASFYEILPCCARFRCSDLIMEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYVHSTPGGSGSTNPPVVSTVYAYIGTPPAQRQLSCLVWRLGPTHFLEEVLTAANVGIIYELGPNYVGSFQAVCTPCKDSKSETGSLSLVSLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLFKKKRGLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLMR---------DFQLIPKLLLTLRDMSLSQPTLAAISNVLSFLLQGFQS----SNDLLRFGQFISSTLPTFAVCEKFVVMEVNNEEKLEPGADDDFGGLVSANLIILRNRLLDVLLKLLYTSKEKTTVNLQACEELVKILGFDWAIMFMEEHLHSTTVTAAMRILVVLLSNPSILLRFKEGVTGGGWLDQTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFSILQSLLPKHTNVPALYFLLMTLFLQQPVTELPENL-------------------------QFDLDSIWTFIFGVPA---------SSGNVFSS-------------------------IHNVCTEAALLLLAMLRTMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWISPEFLCALAASVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFASDSGMNRSQSEYCN----------MGTKTYLTNHPAKKFVFDFMRVLVIENLCLTPASKQTPLIDLLLEASPERSTRAQQKEFQTYILDSVMDHLLAADVLLGEDASLPITTGGNYQVLVNNVFYFTQRVVDKLWQGMFNKDSKILVDCIIQLISQSKRRSQGLSLEAIYNCLNRTILYQFSR------AHKTVAQQVALLDSLRVLTVNRNLILGPGNHDQEFITCLAHCLINLHMGSNPDGFGLEAEARMTTWHIMIPSDIEQDGVYQDVSEGRQLLLKAVNR-----VWIELIHSKKQVLEDIFKVAFPVNERGHVDINTVRPFIEEATLRAWQNHLVYEKKCTSKGE-----ALVPTSQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSAQEISQWVFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWNQTEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKVVRNDMFYIHYPYIP-------DAEHETNTMKPARYRRAVSYDSK--------------DYYMRLMPG---NPAVFQDTVEESSDGETAHNEPEHG-EDTIARVKGL--------VKAPLKRSRSAPDGGED-----------ENQE------MLQDQL--------SEGSSVEE--------DEKMDSTTLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVVDGFTMTVTREIRDIETLPVNMHEPIIPRGARQGPSQLKRNCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADFDSEELDLTSPKTFRNLAKPMGAQTEDRLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDYVSSHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---GRINGDLTSMS-LPVGTACDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPAWNKTFAWGYADLSCRLGTYESDKAVVVYECLSEWGQILCTICPNPKMVITGGTSTVICVWEAGTSKEK---------------AKSLNLKQALIGHTDTVTCLTASLAYHIVVSGSRDRTCIIWDLNKLAFVTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPIVSVNTFIGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPADTMEMPDDCQDEHLGLDCYDESSDSDAEDQSVSQDIKTKESQPQGNDSHRPRASSARAGLTAWSGDSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSENQSKVQLPQIQSGGQASQTDVR-HYNKLKTGYRWERQLVFRSKLTMHTAFDRKDNAHPAEVTALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGMDNCSGCAVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERGTEEATRN 3493          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: A0A5F8H7K0 (WD repeat and FYVE domain containing 3 OS=Monodelphis domestica OX=13616 GN=WDFY3 PE=4 SV=1)

HSP 1 Score: 2377.44 bits (6160), Expect = 0.000e+0
Identity = 1448/3881 (37.31%), Postives = 2157/3881 (55.58%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAG-ISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXX------------XXXXXXXXXXXXHYLKTIVSDSSF----IPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQD----------FCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYENPIG-----SLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLL---MDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWY-------NPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQID-PMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSE-----PQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDG---INIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQ 11383
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE+    Q +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP +N  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+    E+ +D+++ L+ LI  LTT G  EL+P   ++    + + GF +P P  K  S+RN  AF VLQ+ FL A+T++L   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+ +    + +  K  ++   H+ IFK+V +++G+LE+ VN LH YA  LK  Q      DS NN    +Q +L LL+++ LT+L+   + N  +FR+ GG+ C  ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E   S   K  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +A+R LGCF SD+  I   N    N+Q        +   L  D +  +SVS                 L  CS+          +  ++Y  A + F++                        S  +H   ++ + S +    + +  + P  PS + +  ++++HP A+++++ L+ ++    +Q  H ++LQ+ +   L  L   +RN Q+MCE+  +   LL     A+ +E+H LH     +FERLA+Q + P  +R+FLRLA+PL C     N      +   S+  Y+P           G G D          +    S ++   G  + LTRVK L+ +TT                    D      A  P+FVE +   EGFGCLFLPS+AP +  +  ++   ++        G G   R FPP  G S+S+W C++ FSS    HP+RLL+L R    S +   CL I ++++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +++GQL+ T KL+YI      S  +   ++++VYAYIGT P   ++++L WR GP HF+EE L  S V+ I  LGPNY+G+FQ    P  D ++  G     SLV EEKV F LYA ++S  T+ +I K+YN+LD   IA+QL +   E ++P++++HN+AGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL   L  R + L       P    I+  LS L++    + N  +DL RFGQF+  TL      E  + +  NN+  L++   ++   L+    +  +  L  +   +   + E      +  E+L++ LGFDW+L+F +  +H +TV  AMR LV LLS    ++KF++G+   GWL  TD VL  + G +L   +  +    +A+REIN D+CH PGF  LQS LP H  +P +YF+L+AL L   +  +P+NL+ + P            IS   NQ  QF+ +S+  F+FG                  ++GP+   ++ +                   C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +  S+ M  +FL  L   ++P +           D  + S  ++   F+ ++ +  +++E C     N+ +   +T     + PA+K + DF +++I+D   L P +    +ID++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  ++I ++ +LI+Q ++R   ++ +++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G ++ G+        +TW+       +PDS  + ++ +   Q+    +N         +W E+  +KKQ LEE FK+      +   ++    P IE+  LK W +++  E    +     R    +P +  + S +++G  +S         KL    RN     L+                        +++S++E   W+  HI+VV++L+D     + +++   + Y+  +W  +E EL RERGLWGP +GS LDKWML+  EGPCRMRKKM+ N+ FY HYPY P         E    V +  +++ A S D + Y              Y +L+       S NP  V++ I  S+E  E + +  E    G        DT   +KG   +    + ++  P    D  DEE  N++ +     +DS         SR E        E+  D++ ++                             ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          RR  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPW+LADY+S+ +DL +P TFR L KPMGAQ++ RL Q++KRYR+W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LG+++LPPWAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G AAV+AVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+   ++  N  +  P  P      ++++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C + +++ITGG STVV VW M  +  K               A  L+L+  L GH + VTC   + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT TGRS+QI+   MS M +WD  NV++TG +DGVVR W +E++QVP + +    +  E     P+A   Q G +   S    +       D +E      S+ ++ + A    S  A ++ + D  SD+         S++++ D        +DG   +N  E      +Q  L      P    +   L+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ I++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPNTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEVVGGAQNELP------------------LAERRGLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPYNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAES-KDALKDLVNLITSLTTYGVSELKPA-GITTGAPFLLPGFAVPQPAGKGHSVRNIQAFAVLQNAFLKAKTNYLPQIILDAITNIYIADNANYFILESQHTLSQFAEKISKLP-EVQTKYFEMLEFVVFSLNYIPCKELISVSILLKSSSSYQCSIIATKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAAFLKDPQALNEQGDSKNNSSVEDQKQLALLVMETLTILLQGSNTNAGIFREFGGARCAHNIVKYPQCRQHALMIIQQLVLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRTRTVFRKVGGFVYITSLLVAMERSLSCPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRFLGCF-SDLRKISPLNVFPSNTQP-------FQRLLEDDLTSVDSVS---------------PTLRHCSK----------LFIYLYKVATDSFESHAEQIPPCLTNESSLPSPWGTPAVSRKRHAYHSVSTPSGYSSKNVADLKQQPAAPS-LQSSDAVVIHPGAMLAMLDLLSSV-GSPSQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPVVLREFLRLANPLNCGAWDKNLLKQYRIHKPSSLSYEPEMRGSMVTSIEGLGSDNVFSLHEDNHYRISKSLVKSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSAVTPAFVEFDTSLEGFGCLFLPSLAPHNAPTNNAATAGLTDGTVISGIGSGE--RFFPPPSGLSYSSWFCIEHFSSSPNHHPVRLLTLVRRANSSEQHYVCLAI-VLSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGDLIVEGQWHHLVLVMSK-GMLKNSTAALYIDGQLVSTVKLHYIHSTPGGSGSANPPVVSTVYAYIGTPPAQRQLASLVWRLGPTHFLEEVLPISSVNIIYELGPNYVGSFQAVHVPCKDSKSESGIQSPVSLVPEEKVSFGLYALSVSSLTVAKIRKVYNKLDSKAIAKQLAISSHENATPVKLLHNSAGHLNGPARTVGAALIGYLGVRTFIPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIVAISNVLSFLLQ---GFPNS-NDLLRFGQFIASTLPTFAVCEKFVVMEINNEEKLDTGTEEDFGVLVSANLILLRNRLLDILLKLIYSSKEKTSINIQACEDLVRTLGFDWLLMFTEEHLHSTTVTAAMRILVVLLSNQSVLIKFKEGLSGGGWLEQTDSVLTNKIGTVLGFNVGRSAGGRSAIREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVTELPENLQVSVPV-----------ISSRCNQGCQFDLDSIWTFIFGVPA---------------SSGPVVSSIHNV-------------------CTEAAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLASMWMSPEFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFKAFAVDTGMNRSQSEYC-----NVGSKTYLT-----NHPAKKFVFDFMRVLIIDNLCLTPASKQTPLIDLLLEASPERSTRTQQKEFQTYVLDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLIDFIIQLIAQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFISCLAHCLINLHVGSHVDGFGLEAEARMTTWHIMIPSDIDPDSSCSQDVSEGR-QLLIKAVNR--------VWTELIHSKKQTLEELFKVTLPVNDRGLVDITIARPLIEEAALKCWQNHLAHEKKCIS-----RGEALVPSTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSMQEISQWMFTHIAVVRDLVDTQYKEYQERQQNALKYVTEEWCQIEYELLRERGLWGPPIGSHLDKWMLEMTEGPCRMRKKMVRNDMFYNHYPYMP-------ETEQETNVLKPARYRRAVSYDSKEY--------------YMRLA-------SGNPAFVQDAIIESSEG-ESTQQEPE---HGE-------DTIAKVKG--LVKPPLKRSRSAP----DGGDEE--NQEQLQDQIAEDS---------SREE--------EEKTDNATLL----------------------------RLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNMHEPIIPRGARQGPSQLRRSCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWVLADYDSQEVDLANPKTFRNLAKPMGAQTDERLTQYKKRYRDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGNVILPPWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPAAVDAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVRSRLNGDNSGLSVPPGPT-----SDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAVTVYECLSEWGQILCAICPSPKLVITGGTSTVVCVWEMGTSKEK---------------AKTLTLKQALLGHTDTVTCSTASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPVVSVNTFTGRSQQIVCCCMSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPIEDLEMQEDCPEAQIGQEG-QDEESSDSEAEESSIIQDPKETPSQPGSVSHRPRAA----SCRAAAVWSADSGSDDSRR-----WSDQLSLD-------EKDGFIFVNYSEGQPRVHLQGPLNHPHPYPVDVRHYNSLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEITALGISKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHER 3499          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Match: M7BQI5 (WD repeat and FYVE domain-containing protein 3 OS=Chelonia mydas OX=8469 GN=UY3_12513 PE=4 SV=1)

HSP 1 Score: 2369.35 bits (6139), Expect = 0.000e+0
Identity = 1455/3894 (37.37%), Postives = 2160/3894 (55.47%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA--GISDSVNN----EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQN-WSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPN---PMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYI----------SQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNRE---QENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQN---PILDYEN------PIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEP-----KIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQS-QFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSS-----------DPGMKSSPKKINLFSPESII-FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYN--PDSISTDNIKDNE-NQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRP-----------YHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNE------DPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDE----------ETFNKDNMFSDTVDDSDFPLDTEKTSRSE-SKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQ--AVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTL--LKSLSQP---QMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQS 11386
            MN V+RI+    +   +     +D    L  L+ LF +      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE+    Q +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP  N  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SSDV+Q LLDDFR  QGY  + + L++LE+    E+ +D+++ L+ LI  LTT G  EL+P   ++    + + GF +P P  K  S+RN  AF+VLQ+ FL A+T++L   IL+AI  IY  D ANYFILE Q+T   F+EK+ K    VQ +   +++ +V +LNY+P KE+ S+S+++K+      + + +K  ++   H+ IFK+V +++G+LE+ VN LH YA  LK    A     DS NN    +Q +L LL+++ LT+L+   + N  +FR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E       K  W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +A+R LGC+          +S  ++  N + SN   +   L  D    +SV+                 L  CS+          +  ++Y  A + FD                 H   ++ +   + P     +KL    + + +  ++I+HP A+++++ L+ ++     Q  H ++LQ+ +   L  L   +RN Q+MCE+  +   LL     A+ +E+H LH     +FERLA+Q + P  +R+FLRLA+PL C         +  +   S+  Y+P   +       G G D    +          S ++   G  + LTRVK L+ +TT                    D      +  P+F+E +   EGFGCLFLPS+AP +  +  +    +         G G   R FPP  G S+STW C++ FS+    HP+RL ++ R    S +   CL I I+++ +  ++VSTKEE+  N      E  S        A F C  L+ E  W HLVL   + GM+K+S+ + +L+G L++T KL+Y+  +   S  +   ++++VYAY GT P   +IS+L WR GP HF+EE L  S VS I  LGPNY+G+FQ    P  D ++      P+ SLV EEKV F LYA ++S  T+ RI K+YN+LD   IA+QL +   E ++P++++HN+AGHL+G  R++GA LIGY G+R F P P+   +  +GG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL   L  R + L       P    I+  LS L++   S     +DL RFGQ +  TL      E  + +  NN+  LE+   ++   L     +  +  L  +   +   + E      + +EEL++ LGFDWI+LFM+  +H +TV  AMR LV LLS    ++KF++G+   GWL  TD VL  + G +L  N          +REIN D+CH PGF  LQS LP H  +P +YF+L+AL L   +  +P+NL+ + P +           S   NQ  QF+ +S+  F+FG                       G +++ I+                 +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +  S+ M  +FL  L   ++P +           D  + S  ++   F+ ++ +  +++E C     N+ +   +T     + PA+K + DF +++I+D   L P +    ++D++LE   E +T+   K+FQT  ++S+ +H +A D+L G++  LP+  GGSY  + NN++YF  RVVDK+WQ  +  +  +++ ++ +LISQ ++R   ++ +++Y   NR IL++ SR        K + + +  L      T   + I  P N D EF+ CL H LI L  G  + G+        +TW+   P  I  D + + + ++ + L L    R     +W E+  +KKQ+LEE FK+      +   +++   P IE+  LK W +++  E    +     R    +P +  + S +++G  +S         KL    RN     L+                        +++S +E   W+  HI+VV++L+D     + +++   + Y+  +W  +E EL RERGLWGP +GS LDK ML+  EGPCRMRKKM+ N+ FY  YPY P           +   P +  ++     +  +++ A S D + YY               +L+       S NP   ++ I  S+E      +PE    +T + ++G          S P  GD +  ++ QD +      ID+E++          E   K   F +T  D    LD      S+ S++  LN + S  S                                HM G   +I  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P          +R  S  F++ +I+EVHKRRYLLQPIAVEVF GDGRN+LLAF K ++NK+Y +F+ V  SLT ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+S  LDLT+P TFR L KPMGAQ+E RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD++LPPWAKGD REFIR HREALECD+VSAHL+EWIDLIFGYKQ G AAVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+    S IN  +  M+ +   +  +++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK LIPP + +  AWG++D S R+G Y+SDK + VYE    +G I+C +C N +++ITGG STVV VW M  +  K               A  L+L+  L GH + VTC   + +Y+++VSGSRDRTCI+WDL ++ +L QL GH APV+A+CI+E+TG + SCAGTY+H+WSI+G  + SVNT TGRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP + +    +  E Q     +Q G E+     +  +  + E D + I Q +K  E++SQ  + +   +  S      S+          GS++        S+  +DG   V   N S+ Q+ +     ++ P   ++R +  KL+ G+ W+RQL+FRSKLTMHTA++R DNA+P+ I++L IS+DH  I VGD RGRVF WSV  +PGRS ADHW++DE  + C GC +RFSLTERRHHCRNCG +FC KCS+ ++EI RL++  PVRVC  C+Y++  ++ 
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFTELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSTMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEINQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHVPEVVGGAQNELP------------------LAERRTLLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPCNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSDVSQTLLDDFRIWQGYNFLCDLLLRLEQAKEAES-KDALKDLVNLITSLTTYGVNELKPA-GVTTGAPFLLPGFAVPQPAGKGHSVRNIQAFSVLQNAFLKAKTNYLAQIILDAITNIYIADNANYFILESQHTLSQFAEKISKLP-EVQTKYFEMLEFVVFSLNYIPCKELISVSILLKSSTSYQCSIIAMKTLLKFTRHDYIFKDVFREVGLLEVMVNLLHKYAALLKDPTQALNDQGDSRNNSSFEDQKQLALLVMETLTVLLQGSNTNAGIFREFGGARCVHNIVKYPQCRQHALMIIQQLVLSPSGDDDMGTLLGLMHSAPPTELQLKTDILRALLSVLRESHRTRTVFRKVGGFVYVTSLLVAMERSLCSPPKNGWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFKTEIQYEKLADAVRLLGCYS---------DSRKISPLNVFPSNTQPFQRLLEDDLISMDSVA---------------PTLRHCSK----------LFIYLYKVATDSFDR----------------HAYHSVSTPPVYPPKNIADLKLHTGATLLQSSDAVIIHPGAMLAMLDLLASV-GSTAQPEHALDLQLAVANILQSLVHTERNQQVMCEA-GLHARLLQRCSAALADEDHSLHPPLQRMFERLASQALEPMVLREFLRLANPLNCGAWDKKLLKLYRVHKPSSLSYEPEMRSSMVTSMEGLGSDSVFSLHEDNHYRISRSLLKPAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSSVTPAFIEFDTSLEGFGCLFLPSLAPHNAPTNNAVTTGLVDGAVVSGIGTGE--RFFPPPSGLSYSTWFCIEHFSTPPNNHPVRLFTVVRRANSSEQHYVCLAI-ILSAKDRSLIVSTKEELLQNYVDDFSEESSFYEILPCCARFRCGDLIVEGQWHHLVLVMSK-GMLKNSTAALYLDGLLVNTVKLHYVHSSPGGSGSTNPPVVSTVYAYTGTPPAQRQISSLVWRLGPTHFVEEVLPLSSVSTIYELGPNYVGSFQAVYIPCKDSKSEGVSPSPV-SLVPEEKVSFGLYALSVSSLTVARIRKVYNKLDSKAIAKQLAVSSHENATPVKLLHNSAGHLNGPARTIGAALIGYLGVRTFVPKPVATTLQYIGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEASKNAKLMREFQLIPKLL---LTLRDMSLS-----QPTIAAISNVLSFLLQGFPS----SNDLLRFGQVISSTLPTFAVCEKFVVMEVNNEEKLETGTEEDFGGLASANLILLRNRLLDILLKLIYTSKEKTSVNLQASEELVRTLGFDWIMLFMEEHLHSTTVTAAMRILVVLLSNQPILIKFKEGLSGGGWLDETDSVLTNKIGTVLGFNVGRSAGGRSTVREINRDACHFPGFPVLQSFLPKHTNVPALYFLLMALFLQQPVTELPENLQVSAPVS-----------SSRCNQGCQFDLDSIWTFIFG------------------VPASSGTVVSSIN----------------NVCTEAAFLLLGMLRSMLNSPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLTSMWMSPEFLCALAATVFPFNIRPYSEMVTDLDDEVGSPAEEFRAFAADTGMNRSQSEYC-----NVGSKTYLT-----NHPAKKFVFDFMRVLIIDNLCLTPASKQTPLVDLLLEASPERSTRTQQKEFQTYILDSVMDHLLAADVLLGEDASLPITSGGSYQVLVNNVFYFTQRVVDKLWQGMFNKESKLLVDFIIQLISQSKRRSQGLSLDAVYHCLNRTILYQFSR------AHKTVPQQVALLDSLRVLTVNRNLILGPGNHDQEFICCLAHCLINLHMGSGVDGFGLEAEARMTTWHIMIPSDIEPDGVYNQDISEGRQLLLKAINR-----VWTELIHSKKQVLEEVFKVTLPVNDRGHVDIVVARPFIEEASLKCWQNHLAHEKKCIS-----RGESLVPTTQSKLSRVSSGFGLS---------KLTGSRRNRKESGLNK-----------------------HNLSTQEISQWMFTHIAVVRDLVDMQYKEYQERQQNALKYVTEEWSQIEYELLRERGLWGPPIGSHLDKCMLEMTEGPCRMRKKMVRNDMFYIQYPYMPETEQETNLLSDFSSKPPETPDDTIPQKKPTRYRRAISYDSKEYY--------------MRLA-------SGNPAVFQDTIEESSEGEATQQEPEHG-EDTIARVKGLVKPPLKRSRSAPDGGDEENQEQLQD-QIAEGSSIDEEEKTDNTTLLRLLEEGEKVQYFRNT--DQLLYLDFYFVPFSDFSRVMVLNVDSSSRSV-------------------------------HM-GVPLQIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTATREIRDIETLPPNLHEPIIPRGARQGPSQLKRTCS-IFAYEDIKEVHKRRYLLQPIAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLT-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSAELDLTNPKTFRNLAKPMGAQTEERLAQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWYSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGCKQNGTKLGDVILPPWAKGDPREFIRVHREALECDFVSAHLHEWIDLIFGYKQQGPAAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---SRINGDVVGMS-VPPGSTNDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLIPPTWNKTFAWGYADLSCRLGTYESDKAVIVYECLSEWGQILCAICPNPKLVITGGISTVVCVWEMGTSKEK---------------AKTLTLKQALLGHTDTVTCSTASLAYHIIVSGSRDRTCIIWDLNKLSFLTQLRGHRAPVSALCINELTGDIVSCAGTYIHVWSINGNPVVSVNTFTGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEILEMQEDCPEAQIGQEA-----QDEDSSDSEADDQCISQDTKPQESQSQPNSTSHRPVPSSSRAAAWSA--------DSGSDDSRRWSDQLSLDEKDGFIFV---NYSEGQTKVHPHAQVNHPNHVEVR-HYSKLKPGYRWERQLVFRSKLTMHTAFDRKDNAHPAEITALGISKDHSRILVGDGRGRVFSWSVSDQPGRSAADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYNLQHERG 3535          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:103029491])

HSP 1 Score: 987.638 bits (2552), Expect = 0.000e+0
Identity = 458/769 (59.56%), Postives = 586/769 (76.20%), Query Frame = 2
Query: 8255 QWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVP 10561
            Q  +   +  ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDGFT+  TREI +I  +P ++HEPI+P     +    +R  S  F++ +I+EVHKRRYLLQP+AVEVF GDGRN+LLAF K ++NK+Y +F+ V  SL  ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY++E LDL +P TFR L KPMGAQ+++RL Q++KR+++W+DP+GETP YHYGTHYSSAMIVA YL+RMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG+KQNG  LGD++LPPWAKGD REFIR HR+ALECDYVSAHL+EWIDLIFG+KQ G  AVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR+    S +N +I P  P + S+ A+++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK L+PP + +  AWG++D S R+ NY+SDK + VYE    +G I+C +C N +++ITGG ST + VW MS    K               A  L+L+  L GH +AVTCL  +++Y+++VSGSRDRTCI+WDL ++ ++ QL GH APV+A+CI+E+TG + S AGTY+H+WSI+G  +AS NT TGRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP
Sbjct: 2492 QKTDNTTLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGFTMTVTREIRDIETLPANLHEPIIPRGARQSQSQLKRSCS-IFAYEDIKEVHKRRYLLQPMAVEVFSGDGRNYLLAFQKGVRNKVYQRFLAVVPSLA-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDAEELDLNNPKTFRNLSKPMGAQTDDRLIQYKKRFKDWEDPNGETPAYHYGTHYSSAMIVASYLLRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGSKQNGTRLGDVILPPWAKGDPREFIRVHRQALECDYVSAHLHEWIDLIFGFKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKRVR---SKLNGEI-PGMPASVSSTADKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLVPPAWNKTFAWGYADLSCRLANYESDKAVIVYECLSEWGQILCAICPNPKLVITGGTSTAICVWEMSTAKEK---------------AKTLTLKQALLGHTDAVTCLTASSAYHIIVSGSRDRTCIVWDLNKLSFVTQLRGHRAPVSALCINELTGDIVSSAGTYIHVWSINGNPIASANTFTGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVP 3225          

HSP 2 Score: 769.615 bits (1986), Expect = 0.000e+0
Identity = 546/1744 (31.31%), Postives = 880/1744 (50.46%), Query Frame = 2
Query: 2603 LKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQ-----------MQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEV---FGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYEN---------PIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIE-----IRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKC--GNVINNIRNTEMITLES---LNSLPARKLIMDFFKMIIVDYFSL-PKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRP 7669
            +K I     ++ NP + P  P        +++HP AV++++ L+ ++  D  Q  H ++LQ+ +   L  L   +RN QI+CE+  +   LL     AM +E+HPLH     +FERLA+Q + P  +R+FLRL +PL C            +   S+  Y+            G G D    +++           ++   G  + LTRVK L+ +TT                    D      A  P+FVE +   EGFGCLFLPS+AP + SS  ++   VS        G G   R+FPP  G S+S+W CV++FS+   +HP+RLL++ R    S +   CL I ++++ +  ++VSTKEE+   + +   E  S        A F C  L+ E  W HLVL   + GM+K+S  + +++GQL+ T KL+Y+      S  +   ++++VY+YIGT P   ++S+L WR GP HF+EE L A+ V+ I  LGPNY+G+FQ   L  ++         P+ +LV EEKV FSLYA ++S  T+ +I K+YN+LD   IA+QL +   E ++P+++IHNAAGHL+G  R++GA +IGY G+R F P P+   +  VGG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++    S  + ++ K  R   ++  LL L L ++ +         P  T I+  LS L++    + N   DL RFGQF+  TL      E  + +  +N+  ++     +   L+      +RN    I+LK+L +S        +  EEL++ LGFDW+L+FM+  +H STV  A+  LV LLS    + +F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQ+LLP H  +P++YF+L+AL L   +  +PD+L+                +S     +QF+ +S+ +F+FG                  +A  +G + N                    +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +   +    DFL  L  A++P +   ++   + +     E+   TE  K    +   N   +E   + S   L + PA+K + DF K++I+D   L P +    +ID++LE   E +T+   K+FQ+  ++S+ EH +A D++ G++  +P+  GGSY  + NN++YF  RVVDK+WQ  +  +  +++ ++ +LISQ ++R   ++ +S+Y   NR IL++LSR        K + + +  L      T   + +  P N D +FV CL H  I L  G N+ G+        +TW+    I ++N  D  +     +  + +      +W E+  +K+Q+LE+ FK+      +   ++ +  P +E+   K+W +++  E    +     R    +P +  + S +++G  +S+    + S K + M++                                N++S +E   W+  HI+VV++L+      + +++   + Y+  +W  +E EL RERGLWGP +GS LDK+ LD  EGPCRMRKKM+ N+ FY HYPY P
Sbjct:  823 VKAITDLKLYLGNPSQHPSDP--------VVIHPGAVLAMLDLLASVSSDA-QPEHALDLQLAVANILQVLVHSERNQQILCEA-GLHSRLLQRCSCAMGDEDHPLHPPLQRMFERLASQALQPMVLREFLRLGNPLNCGAWDKKLLKQYRVHKPSSLSYEAEARNSMTTSMEGFGPDSVFAVNEDNSQYRISRSLVRSAEGSTVPLTRVKCLVSMTTPH------------------DIRLHGSAVTPAFVEFDSSLEGFGCLFLPSLAPHNASSNNANTSGVSDGAVVSGMGTGE--RLFPPPSGLSYSSWFCVERFSTAPHSHPVRLLTVVRRATASEQHYVCLAI-VLSAKDRSLVVSTKEELLQSYADDFSEESSFYEILPCCARFRCADLITEGQWHHLVLVMSK-GMLKNSMATLYIDGQLVSTVKLHYVHSAPGGSGAANPPVVSTVYSYIGTPPAQRQLSSLVWRLGPTHFLEEVLPATSVAAIYELGPNYVGSFQAVYLPCKDSKTEAVPPCPV-ALVPEEKVSFSLYALSVSALTVAKIRKVYNKLDSKAIAKQLAVSSHENATPVKLIHNAAGHLNGPARTIGAAVIGYLGVRAFVPKPVATNLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLACKEMERIKGYQLLAMLLKKKRLLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIELLTESSEAAKNAKLLREFQLIPKLL-LTLRDQSLS-------QPTITAISNVLSLLLQ---GFPNS-YDLLRFGQFLSSTLPTFAVCEKFVVMEVSNEEKIDGGNDDDFGGLLSSNVILLRNRLLDILLKLLFSSKEKSIVNAQACEELVRTLGFDWLLMFMEEHIHSSTVTAALWILVVLLSNQSILGRFKEGLSGGGWLDHTDSVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFPVLQTLLPKHTNVPELYFLLMALFLQQPVTELPDSLQ--------------VHVS-----TQFDLDSIWSFIFGVPAS--------------SATVVGSIHN--------------------VCTEAAFLLLAMLRSMLNLPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLAPMWHSPDFLCALAAAVFPFN---IRPYSEMVTDLDDEAGSPTEEFKAFVADTGMNRSQSEYCNVGSKTYLTNHPAKKYVFDFMKVLIMDNLCLTPASKQTPIIDLLLEASPERSTRTQQKEFQSYILDSVMEHLLAADVMLGEDGSMPITTGGSYQVLTNNVFYFTQRVVDKLWQGMFNKESKLVVEFIVQLISQAKRRSQGLSLDSIYHCLNRTILYQLSR------PHKTVPQQVALLDSLRVLTVNRNLVLGPGNHDQDFVACLAHCFINLHTGSNVEGFGLEAEARMTTWHV--MIPSENEADTPHSQDVSEGRQLLLKAVNRVWTELMHSKRQMLEDIFKVSLPVNDRGHVDIATARPGLEEPAAKSWQNHLAHEKKCIS-----RGETIVPATQSKLSRVSSGFGLSKLTGARRSKKESGMNK--------------------------------NNLSAQETFQWMFTHIAVVRDLVAMQYKEYQERQQNALKYVTDEWAGIEYELLRERGLWGPPIGSHLDKFQLDMTEGPCRMRKKMVRNDMFYIHYPYVP 2389          

HSP 3 Score: 473.396 bits (1217), Expect = 4.067e-133
Identity = 278/758 (36.68%), Postives = 443/758 (58.44%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPN-PEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKT-----CNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLK--KEQDAGISDSVNN---EQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCF 2278
            MN V+RI+    +   +     +D    L  L+ LF++      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL  + +L+      ++CM T S+PST VKCLY+FFDLP+ PE+    Q +                       RR +L   F Q+L ++C + +  EEL +K+DL+LLF A+ SWCP HN  WRK+A +VL TI+ +GLS + +++I+ K+ +S C++N+ +   L  +EIV++F  L   L++SS+V+Q LLDDFR  QGY  + + +++LE+   +E+ +D+++ L+ L+  LTT G  EL+P   L+    + + GF +P P  K  ++RN  AF+VLQ+ FL A++  L   +LEAI  IY  D ANYFILE Q+T   F+E++ +    VQ +   L++ +V  LNYVP KE+ S+SV++K+     C++  T +LL     +L  H+ +F +V +++G+LE+ VN LH YA  LK   +      DS NN   +Q +L  L+++ LT+L+   + N  LFR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S  S  L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E          W+ + + ++ E +  +   LT A++ EP+N  +F   + Y  L +A+R LGCF
Sbjct:    1 MNMVKRIMGRPRQEECSP----QDNALGLMHLRRLFSELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSTMNEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEVNQSE----EASRGWMLLTTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHMPEVPAATQTELP------------------LADRRALLQKVFVQILVKLCSFVSPAEELAQKDDLQLLFSAITSWCPPHNLPWRKSAGEVLMTISRHGLSVNVVKYIHEKECLSTCIQNMQQSDDLSPLEIVEMFAGLSCFLKDSSNVSQALLDDFRMCQGYNFLTDLMLRLEQAKEDES-KDALKDLVNLVTSLTTYGVSELKPA-GLTTGAPFLLPGFVVPQPSGKGHTVRNIQAFSVLQNAFLKAKSGRLARMVLEAIANIYAADYANYFILEAQHTLSQFAERVARLP-EVQAKYFELLEFVVFGLNYVPCKELFSVSVLLKSSTSYSCSITATRTLL-----KLSRHHPVFSDVFREVGLLEVLVNLLHKYAALLKDPTQTHGEHGDSKNNVADDQKQLAWLVMETLTVLLQGSNTNAGLFREFGGARCVHNIVKYRQCREHALMIIQQLVLSPSGDDDMGTLLGLMHSAPSTELQLKTDILRALLAVLRESHRTRTVFRKVGGFVYVTSLLVAMERSLGSQPAGSWEKVNQNQVFELLHTVFCTLTAAMRYEPANSHFFRSEIQYEKLADAVRLLGCF 724          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: lyst (lysosomal trafficking regulator [Source:ZFIN;Acc:ZDB-GENE-070702-1])

HSP 1 Score: 415.231 bits (1066), Expect = 2.400e-115
Identity = 267/798 (33.46%), Postives = 404/798 (50.63%), Query Frame = 2
Query: 8291 GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNME----PSLQP-VKELK--NAVGQ-------IIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSL--QANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCA-----GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
             + E I F  RC  +       G LL G+S  Y ++             +N     H    P+             S  +++ EI+EVHKR + L+  AVE+FL +GR  LLAF   K ++ +Y               H+I   +  + +E  + S         ++TQ W   +I+NF+YL +LN  AGRS+NDLMQYPVFP+IL DY SETLDL  P+ +R L KP+  QS+ +  ++   YR            DDP     PYHYG+HYS++  V  +LVRM PFT+ FL  Q   FD+ DR FHS+  TW  +S  +M D+KELIPEFFYLP FL N   FD G +QN   +  + LPPWA+ D R F+  HR+ALE D VS  L +WIDL+FG KQ G AA+ A+NVFH   Y G +D+ +++DP++R A+   I  +GQ P+QLF   H ++    P  ++  ++    P A     +  F  + +  +    PS  P +K LK    VG        +  +  +G    ++ ++P+  +     K  +  +Y++                 ++WG++D  LR+ +  S+  I   +    +    C    +   L TG    V+  ++               +R +  +A  + +  Q +LYGH + VT L V   Y++L+S SRD TCI+WDL R+CY++ L+GH +PV A+  SE TG +A+       G+ L LW+++G+ +  V+      + I +V  S   +    NV+  G  +GVVR+WS
Sbjct: 2905 ATSEPIRFTRRCISVAPSRETAGELLLGKSGMYFVE-------------DNAAETPHGETEPA-------------SFCWTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVY---------------HNILTSELPNLLEYDNIS---------ALTQLWGSSQITNFEYLTHLNKHAGRSFNDLMQYPVFPFILRDYVSETLDLQDPNIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGAREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNSERVNHVNLPPWARNDPRLFVLIHRQALESDQVSQTLCQWIDLVFGLKQKGKAAIHAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFNATHISRA--GPKLMMEGEL----PAAMGLLVQLAFRESREQAKEVTYPSPLPWIKGLKWGEYVGSPSAPDPVVCFSQPHGERFGSLLALPTRAICGLSRKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYTDNMLRLKSKQSEPPINFIQCSPLHQVTSCAWVPDGCQLFTGSKCGVITAYS---------------NRFSTTMASEMDVESQVHLYGHTDEVTGLFVCKPYSILISVSRDGTCIIWDLNRLCYVQSLTGHKSPVNAVSASETTGDIATVCDSVGGGSDLRLWTVNGDLIGHVHC----REIICSVAFSNQPEGVSVNVIAGGLENGVVRLWS 3626          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: nbeal1 (neurobeachin-like 1 [Source:ZFIN;Acc:ZDB-GENE-130530-544])

HSP 1 Score: 380.563 bits (976), Expect = 4.961e-105
Identity = 241/638 (37.77%), Postives = 333/638 (52.19%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQ-NGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLI-------------------------PPLYTRYVAWGFS-------------------------DGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNER--ILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGR 10279
            K+   +IRE+H RRY L+  A+E+FL D  N+ L F K+++NK+Y++ + +  SL L+   S                     +    +TQ+W   EISNF YLM LNT+AGR+YN+L QYPVFPWILADY SE LDL+ P  FR L KP+   +E       ++Y  ++DP+G    +HYGTHYS+A  V  YL+R+EPFT   ++LQ G FD ADR FHSI  TW++    N  D+KELIPEFFY P FL N N FDLG  Q +   + D++LP WAK    +FI  HR+ALE +YVSAHL+EWIDLIFGYKQ G AAVEA+NVF++  YEG VD+ +I D  +R A+ G I+NFGQ P QL K+PHP +  L  +     ++D   PL        +F H  +     ++ + +    V  ++    N ++S      P +++ V QN CLI                          P   R++A  FS                         D SLRV +    K +  Y     + DI+  L  +     LI+G   T   VW +      P            GL+P   LQ  LYGH + V  + ++   ++ VSG+RD T I+  + R
Sbjct: 1977 KWPLSQIREIHLRRYNLRRSALEIFLIDQTNYFLNFKKEVRNKVYSRML-LLCSLPLHGTRSPQ-----------------ELLKASGLTQKWVNREISNFDYLMQLNTIAGRTYNNLAQYPVFPWILADYTSEELDLSDPCVFRDLSKPVAVLNEKNAKAVREKYESFEDPTGTIDRFHYGTHYSNAAGVMHYLIRVEPFTSLHIQLQSGRFDCADRQFHSIPATWQTLID-NPNDVKELIPEFFYFPEFLENQNGFDLGRLQISKERVNDVVLPKWAK-SPEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCTYEGAVDLDAITDEKERKALEGMISNFGQTPCQLLKEPHPVRLSLEELEKRTSRLDS-CPL-------NVFEHLTELKSFFVEGISDNCALVKAVVPK--NQSHSFISQGSPDTLVTVSQN-CLIGAHGWLPYDKTISNYFTFIKDPTVASPKTQRFLAGPFSPGVDVTARLFVVSHDGKLLFSGGHWDNSLRVTSLLKGKTVGQYIR---HMDIITCLATDYCGIHLISGSRDTTCMVWQVQQQGGAPV-----------GLSPK-PLQV-LYGHTDEVVSVCISTELDMAVSGARDGTVIIHSVRR 2567          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: nbeal2 (neurobeachin-like 2 [Source:NCBI gene;Acc:100330830])

HSP 1 Score: 366.696 bits (940), Expect = 6.733e-101
Identity = 221/599 (36.89%), Postives = 319/599 (53.26%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQ-NGVVLGDILLPPWAKGDSRE-FIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNME---PSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPS-----------SVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL 10273
            K    ++REVH RRY L+  A+E+F  D  ++ + F KK++NK+Y++ +               G +  +    GS S     +   ++TQ+W   EISNF+YLM LNT+AGR+YNDL QYPVFPW+L DY S  LDL  P+ FR L KP+G  +        ++Y  ++DP+G    +HYGTHYS+A  V  Y++RMEPFT   ++LQ G FD ADR FHS+   W+ A   + AD+KELIPEFFY P FL+N N F+LG  Q N   + +++LP WA   SRE FIR HR+ALE ++VSAHL+EWIDLIFGYKQ G  AVEA+NVF++  YEG VD+ +I +  +R A+ G I+NFGQ P QL K+ HP +      S    +ID + P           +  LD +    P +Q V         IIQ      + +A G + +           +     ++  +  P   R+++  FS G            +++       G  + V+  + R+L +GG       W+ S+  +        G                +  HI+ VTCL++      L+SGSRD TC++W +
Sbjct: 2036 KRPLSQLREVHLRRYNLRRSALELFFIDQAHYFINFRKKVRNKVYSRIL---------------GLRPPNLFYFGSRSP-QELLKASNLTQKWVCREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSSVLDLEDPAVFRDLSKPIGVVNPRHAQNVREKYESFEDPTGTVDKFHYGTHYSNAAGVMHYMIRMEPFTTLHIQLQSGKFDCADRQFHSVAAAWQ-ARMESPADVKELIPEFFYFPEFLDNMNGFNLGCLQVNQEQVNNVVLPRWA--SSREDFIRKHRKALESEHVSAHLHEWIDLIFGYKQRGPEAVEALNVFYYCTYEGAVDLDAIANETERKALEGIISNFGQTPCQLLKEAHPPRMSAENASRRQSRIDTLPP---------NLFEQLDKLRDGVPLVQAVVPRNQTRSFIIQGSDVLVSVSANGQIGTHSWLPYDKNIANYFTFSKDPTMSNPKTQRFLSGPFSPG------------VEI-------GAQVLVVSSDGRLLFSGGH------WDCSLRVTMLGKGKMVG---------------RICRHIDVVTCLSLDLCGIYLISGSRDTTCMVWQV 2566          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Match: lrba (LPS-responsive vesicle trafficking, beach and anchor containing [Source:ZFIN;Acc:ZDB-GENE-090311-19])

HSP 1 Score: 365.54 bits (937), Expect = 1.758e-100
Identity = 235/727 (32.32%), Postives = 363/727 (49.93%), Query Frame = 2
Query: 8459 HEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPIS--IINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQAD-LNGTNSNAVGSVPSSVLAV------EQNKCLIPPLYTRYVAW-GFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSA 10585
            H     S P +    +   +  K+ F EIR V  RRYLLQ  A+E+FL +    +  F      K   K +     + +   +   G  Q  +I   S +         S+TQRW++ EISNF+YL++LNT++GR++NDL QYPVFPW++ +Y++E LDLT PS +R L KP+GA +  R   F  R+  W+D   + P +HYGTHYS+A     +L+R+EPFT  FL  QGG FD ADR F SI   W +  Q + +D+KELIPEFFYLP    N+N ++LG   +G V+ D+ LPPWAK    EF+R +R ALE ++VS  L++WIDLIFGYKQ G  AV ++NVF++L YEG V++ +I DP+ R AV   I +FGQ P QL  +PH  +   + ++  +   Q+     +    P+     H   N +P L     +     ++   +  +G  ++ VGS    +  +        ++C I     R++   GF D S RV + D+ KL+++      +G    V CL         +  +++G     + +W  S            G   + G +  ++ +A L GH   VTC +V A             C +W        R L G   P      +E   ++    G +   +SI+G+ L        + K++     + ++  D G  ++ GG  G++ +W +  ++   S   C A
Sbjct: 1960 HPSFTQSDPKI--LAYTEGLHGKWLFTEIRAVFSRRYLLQNTALEIFLANRTAVMFNFADAATVK---KVVHCLPRVGVGTNY---GLPQTRRI---SLATPKQLFKASSMTQRWQRREISNFEYLIFLNTISGRTFNDLNQYPVFPWVITNYDTEDLDLTLPSNYRDLSKPIGALNPKRAAFFSDRFESWEDE--QVPKFHYGTHYSTASFTMMWLLRIEPFTTFFLNFQGGKFDHADRTFSSISRAWRNC-QRDTSDVKELIPEFFYLPEMFVNSNNYNLGVMDDGTVVSDVELPPWAKS-PEEFVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEAVRSLNVFYYLTYEGAVNLSTITDPMLREAVESQIRSFGQTPCQLLIEPHSPRSSAMQVTPLMFTDQMQQDVIMVLKFPSNSPVVHVAANTQPGLNSPAIITVTANRLFAVNKWHGLTASNVGSHRRQITDLLDQSIQVSSQCFIITSDNRFLLLAGFWDKSFRVYSTDTGKLVQIV-----FGHRDVVTCLARSESYIGGDCYVLSGSRDATLLLWYWS------------GKHCSIGDSKFVTPRAILTGHDCEVTCASVCAD-----------CCGLW--------RVLRGVCGPRLLQASTEGHCVIYYDQGHFC-TYSINGKLL--------QHKELEDKIRAMLLSKD-GQYLLCGGDGGILSVWQVHDLKQLFSYPGCDA 2625          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000320.1 (pep scaffold:Pmarinus_7.0:GL481331:460:21348:1 gene:ENSPMAG00000000288.1 transcript:ENSPMAT00000000320.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 691.419 bits (1783), Expect = 0.000e+0
Identity = 338/560 (60.36%), Postives = 419/560 (74.82%), Query Frame = 2
Query: 8447 PIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESET--LDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPA-ERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNAS--KPTAS 10111
            P  + +P++P   T +  +H ++   KFS+  +REVHKRRYLLQP+AVEVF  DGRN+LL FP+ ++NK+Y +F+ +A SL  ++  S+SGQ  N+ +EAGS  + S  +GE+SVTQRW  GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE   LDLT P TFR + KPMGAQ+  RL QF+KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS++D W SAS++NMAD+KELIPEFFYLP+FL N+N ++LG KQNG+ LG++LLP WAKGD+REFIR HREALECDYVSAHL+EWIDLIFG KQ G  AV + NVFHHLFYEG VDIYSI DPLK +A IGFINNFGQIPKQLFKKPHP KR      + +K      P AS+ PA + LF+H+LD + PS  P+KELK  VGQI+  +               VLAVE+NK L+PP + R  +WGF+D S R+ NYD+DK   V+E    +G ++C +C + + ++ GG +TV+ VW M       KPT  
Sbjct:    1 PPRLQDPVIPRG-TRSPPSHPQRACSKFSYEGVREVHKRRYLLQPMAVEVFSNDGRNYLLVFPRGVRNKVYQRFLTIAPSLA-DSSESVSGQNPNASVEAGS-GLLSGLVGERSVTQRWVHGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYQSEEQELDLTDPRTFRDMSKPMGAQTMERLEQFQKRYQDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQTFLRLQGGHFDLADRMFHSVRDAWLSASRNNMADVKELIPEFFYLPDFLQNSNHYNLGCKQNGIWLGEVLLPNWAKGDAREFIRVHREALECDYVSAHLHEWIDLIFGCKQQGPMAVASTNVFHHLFYEGQVDIYSITDPLKLTATIGFINNFGQIPKQLFKKPHPAKR------VGSKPSGDTNPGASAGPARDCLFFHHLDCLTPSPVPLKELKGPVGQIVCTE-------------RGVLAVEENKVLLPPGFQRTFSWGFADLSCRLCNYDTDKAPVVFECMWEWGPLLCAVCPDAKTVVCGGTATVLCVWEMQGGGKDRKPTVG 538          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000322.1 (pep scaffold:Pmarinus_7.0:GL481331:12961:21303:1 gene:ENSPMAG00000000288.1 transcript:ENSPMAT00000000322.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 558.14 bits (1437), Expect = 9.166e-180
Identity = 276/440 (62.73%), Postives = 332/440 (75.45%), Query Frame = 2
Query: 8804 EKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESET--LDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSG-ETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPA-ERLFYHNLDNMEPSLQPVK----------ELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNM 10081
            + GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE   LDLT P TFR + KPMGAQ+  RL QF+KRY++W+DP+G ETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS++D W SAS++NMAD+KELIPEFFYLP+FL N+N ++LG KQNG+ LG++LLP WAKGD+REFIR HREALECDYVSAHL+EWIDLIFG KQ G  AV + NVFHHLFYEG VDIYSI DPLK +A IGFINNFGQIPKQLFKKPHP KR      + +K      P AS+ PA + LF+H+LD + PS  P+K          +LK  VGQI+  +               VLAVE+NK L+PP + R  +WGF+D S R+ NYD+DK   V+E    +G ++C +C + + ++ GG +TV+ VW M
Sbjct:    1 QHGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYQSEEQELDLTDPRTFRDMSKPMGAQTMERLEQFQKRYQDWEDPNGSETPAYHYGTHYSSAMIVASYLVRMEPFTQTFLRLQGGHFDLADRMFHSVRDAWLSASRNNMADVKELIPEFFYLPDFLQNSNHYNLGCKQNGIWLGEVLLPNWAKGDAREFIRVHREALECDYVSAHLHEWIDLIFGCKQQGPMAVASTNVFHHLFYEGQVDIYSITDPLKLTATIGFINNFGQIPKQLFKKPHPAKR------VGSKPSGDTNPGASAGPARDCLFFHHLDCLTPSPVPLKDHYLFILSICQLKGPVGQIVCTE-------------RGVLAVEENKVLLPPGFQRTFSWGFADLSCRLCNYDTDKAPVVFECMWEWGPLLCAVCPDAKTVVCGGTATVLCVWEM 421          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008664.1 (pep scaffold:Pmarinus_7.0:GL477107:533344:566732:-1 gene:ENSPMAG00000007824.1 transcript:ENSPMAT00000008664.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 501.13 bits (1289), Expect = 1.975e-148
Identity = 428/1501 (28.51%), Postives = 695/1501 (46.30%), Query Frame = 2
Query: 2687 SIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCR--YQPHNCAEFKLDKNGSGQDFC--TYISQ-MQRP-NGGPISLTRVKSLIGITTQ-QNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPC-----EMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITS-VYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIG----NFQNPILDYENPIGS----LVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLES--LNSLPARKLIMDFFKMIIVDYFSLPKNSYQH--VIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPG-----------------GSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQL-----INGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSN----AESLWQEISTNKKQLLE 7030
            + +VHP AV++ + L+P++          + LQ  +++RL  L   +R+ Q++ E+  +   LL     A+ +E HPLH      FERLA   + P  +R FLRL +PL C     ++ D+ T  +       + P +              F    YIS+ + RP  G  + LTR+K L+ +TT    + +   VP                   P F+E +M  EGFGCLFLPS+APQ+   G S     +        G     RVFPP  G S+S W+CV++  S +  HP+RLL+L R   GS+  ++CL +S++   +  +L+ T+E++     QE       ++  ++  C       L QE  W HLVL  +R G++K SS S +++GQL    KL+YI         + G      VY Y+GT P   + S L WR GPVH +EEPL  + V+ I  LG ++ G      Q        P GS    LV EE++ F LY  + S+ T+ +I K YN+ D   +A+Q+ L   E  +P+ ++HNA+GHL G  R++GA +IG  G+R  +  P+   + CVGG  +LLG+LAMA D E LYA  K +   +  +    +E+E   GY+L++ LLK+KR LL++    L + L G+         +E G+++     SL+       F +++ DL +W H                 H+S      VD   +++SS  D++  R     + +L L L+ +++ ++    + PL+      +++L+ L++       D+  +GQF+  TL     SE  + L  +   D ++    +   L+  RN+ F     +        T+  K  EE+L+ LGFDW+LLF+Q  +HP+TV +AMR LV+LLS    + +F++G    GWL  T  ++  +            P  L E    +C LPGF  L S LP H  +P +YF L+AL L   I ++P+N++   P                    Q + +S+  +  G               S ++A P                           C EA   LL M+R  +NQ       E  +W+ +YP+T L+F  YLYH+     +V    +FL  L   ++P +               P S + T +          R+ +M++  S  L+  P+RKL++DF + I VD       S Q   ++D++LE   E  TQ   +++QT  + S+  H  + D LS Q      G                 G+Y  + N I+YF  RVVDK+WQ  +  +P ++ +++  LISQ ++R   ++ + LY   NR +L++LSR       ++   +         +   + + +  P N   +F  CL+H L+Q+     ++G  +   S W+    +ST +  D E     L      R+        +WQE+  +K+ ++E
Sbjct:    1 AFLVHPGAVLAAVDLLPSV-VSATDPQRAVALQCAVVDRLGLLLQSERSQQVLSEA-GLARRLLLRCCGALASEAHPLHDGLQRAFERLACHGLEPPVLRAFLRLGNPLNCA--AWDERDLLTHRVHRGLDVCHDPTSLGSGAHSHRPVSPPFGHRRYISRSLLRPAEGAALPLTRIKCLVAMTTPLHTRHNMAAVP-------------------PPFLEFDMSVEGFGCLFLPSLAPQNAPGGSSVAISPTDDSVTSGMGSAGE-RVFPPPSGLSYSVWLCVERLDSPSQAHPVRLLTLVRRSTGSDRHLACLALSLLPR-DKAVLLCTREQLL----QEMDIPKPRADDSSQDGCVRFVTPELAQEGQWHHLVLVLNR-GVLKPSSASLYVDGQLAGNTKLSYIQATPGGLGSAGGPGAPPLVYGYVGTPPGRRRSSPLAWRVGPVHLMEEPLGHAAVATIFGLGVHHTGCMQAVLQRATEGKSEPSGSATVSLVPEERLSFGLYPLSASLLTVAKIRKAYNKADSRAVAKQIGLSSNENVTPVMLLHNASGHLGGPSRTIGAAVIGNLGVRRSAARPVASSLQCVGGPALLLGLLAMAGDVEALYAATKALVCAVRASELAQREMERIRGYQLLAMLLKRKRSLLNTHSLHLALSLAGT---------VESGRER----DSLS-GLCLPAFRDLVTDLQIWFHSPYDL------------HLS-LLDHFVD--LLTESS--DVEELR-----RIMLGLQLVPKLLHVLKDHTL-PLSKATVMSIARLLSLLLQGFPSSHDMLWYGQFLASTLPTFSVSEKFVELRADEPQDDDA--LIDIESLVSARNI-FLRNQLLEVLLDLLHTSAEKACEEMLRILGFDWLLLFVQGHLHPATVTVAMRILVSLLSNGGILRRFQEGSPGGGWLDLTQALVSGQ-----------TPTVLAE----ACLLPGFSVLLSCLPSHASLPQLYFFLLALFLNRPITSVPENVQSCPPP-------------------QLDLDSIWRYSLGLPP------------SVFSAPP----------------------SVPAPCLEAVLTLLAMLRSTVNQPWQA--EEEGSWLIEYPVTQLQFLQYLYHNVGGLANVWTHPEFLGSLAATIFPYN-------------LRPHSEMNTPSH-----FAKSRSEQMVSARSSFLSQHPSRKLVVDFLRTIAVDSLLQGNVSRQSPPLLDVLLEASPERATQSQQREYQTELLLSIMGHLQSADALSEQTH---AGHRVSFIQLVDSVTGFRRGTYTAVANGIFYFAQRVVDKLWQGMFSREPRLVFNFIAELISQAKQRSQGLSLDGLYGCLNRAVLYQLSR------PRRWPAQQGVLQESLGQLLVHRNLLLGPGNYQPDFFACLLHCLLQIRMHRFVDGFGLEARSAWH---VLSTSDPDDEEASQGALCAMRSARAQLVKLVRRVWQELIGSKRAVVE 1331          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007035.1 (pep scaffold:Pmarinus_7.0:GL477366:176480:246408:1 gene:ENSPMAG00000006333.1 transcript:ENSPMAT00000007035.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 372.089 bits (954), Expect = 1.187e-110
Identity = 252/740 (34.05%), Postives = 370/740 (50.00%), Query Frame = 2
Query: 8489 VNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLA-----GRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPH------------PTKRLLI-------------------PISIINKQIDPM--APLASSAPAERLFYHN-----LDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAW-GFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTV--------VRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTY----LHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMW 10537
            V    +   +  K+ F E+  +  RRYLLQ  A+E+FL    + +   P      I    + +   + +   + +   ++ S   A    +F       ++TQRW++ ++SNF+YLM+LNT+A     GR+YNDL QYPVFPW++A+Y+SE LDLT PS FR L KP+GA +  R   F +RY  WDD   + P +HYGTHYS+A  V  +L+R+EPFT +FL LQGG FD ADR F S+   W + SQ + +D+KELIPEFFYLP    N+N ++LG    GV +GD++LPPWAK    EF+R +R ALE + VS  L++W+DLIFGYKQ G  A+ A+NV+++L YEG V++ SI D + R AV   I +FGQ P QL  +PH            P++  ++                   P++ +     PM   P   +    RLF  N      +    S++ +  L   +  ++ A++       +  V  SV        +      R+V   GF D S RV + D+ +L +       +G    V CL    +  GG   V        V +W  S    +  A G     + G +    S +A L GH   VT +AV+    L +SGS    C+M  L G +  LR L G  A    + ++      A C G Y    L  +S++G    S  T TG + + + ++         G  V+TGG  GVV +W
Sbjct:   10 VKVLAYTESLHGKWLFSEVEAIFSRRYLLQNTALEIFLSSRTSIMFNLPDA---TIVKSVVHLLPRVGIGTLYGLPQARRYSL--ASPRQLFK----ASNMTQRWQQRDVSNFEYLMFLNTIAACTDPGRTYNDLNQYPVFPWVIANYDSEELDLTLPSNFRDLSKPVGALNPQRAAVFAERYASWDD--ADIPAFHYGTHYSTAAFVLMWLLRVEPFTNYFLSLQGGKFDHADRTFSSVARAWRN-SQRDTSDVKELIPEFFYLPEMFTNSNDYNLGVTDAGVAVGDVVLPPWAK-TGEEFVRINRAALESEIVSCQLHQWVDLIFGYKQRGPEAIRAMNVYYYLTYEGAVNMASIRDRVTREAVEAQIRSFGQTPAQLMVEPHAPRSSAMHMVWFPSQTPMMFSNKSQQEVIMVLKFPSNSPVTHVAANTGPMQSPPAILTITCSRLFAINKWNGLCERSSASMEDIMRLPVEIDPLLVANMGLHRRQIMDPVDHSVPTCVNTFTVTAD--NRFVMLGGFWDKSFRVYSTDTGRLKQAM-----FGHWDVVTCLARSEVGVGGDCYVASGSRDATVLLWRWS---GRELALGD--RTMHGNMR---SPRAILTGHDTEVTSVAVSTELGLAISGSIGSPCLMHTLAGEL--LRALEGAGATATPLLLA--ISQDALCFGYYDDGTLLSFSVNGR--LSARTPTGDTTRAMVLSAD-------GQYVLTGGDKGVVEVW 708          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008649.1 (pep scaffold:Pmarinus_7.0:GL477107:529775:566732:-1 gene:ENSPMAG00000007824.1 transcript:ENSPMAT00000008649.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 379.407 bits (973), Expect = 1.577e-107
Identity = 311/997 (31.19%), Postives = 494/997 (49.55%), Query Frame = 2
Query: 2687 SIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQ-QNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITS-VYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKIN--LNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKI----AEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLK 5644
            + +VHP AV++ + L+P++          + LQ  +++RL  L   +R+ Q++ E+  +   LL     A+ +E HPLH      FERLA   + P  +R FLRL +PL C     ++ D+          YQ          +  SG         +  P G  + LTR+K L+ +TT    + +   VP                   P F+E +M  EGFGCLFLPS+APQ+   G S                    RVFPP  G S+S W+CV++  S +  HP+RLL+L R   GS+  ++CL +S++   +  +L+ T+E++      +     +    V     E L QE  W HLVL  +R G++K SS S +++GQL    KL+YI         + G      VY Y+GT P   + S L WR GPVH +EEPL  + V+ I  LG ++ G  Q  +   +    SLV EE++ F LY  + S+ T+ +I K YN+ D   +A+Q+ L   E  +P+ ++HNA+GHL G  R++GA +IG  G+R  +  P+   + CVGG  +LLG+LAMA D E LYA  K +   +  +    +E+E   GY+L++ LLK+KR LL++    L + L G+         +E G+++     SL+       F +++ DL +W H                 H+S      VD   +++SS  D++  R     + +L L L+ +++ ++    + PL+      +++L+ L++       D+  +GQF+  TL     SE  +   L   + S    +  ++   L+  RN+ F     +        T+  K+     EE+L+ LGFDW+LLF+Q  +HP+TV +AMR LV+LLS    + +F++G    GWL  T  ++  +   +L  N    P      REIN ++C LPGF  L S LP H  +P +YF L+AL L   I ++P+N++
Sbjct:    1 AFLVHPGAVLAAVDLLPSV-VSATDPQRAVALQCAVVDRLGLLLQSERSQQVLSEA-GLARRLLLRCCGALASEAHPLHDGLQRAFERLACHGLEPPVLRAFLRLGNPLNCA--AWDERDL----------YQ---------SRPPSGI--------VDNPEGAALPLTRIKCLVAMTTPLHTRHNMAAVP-------------------PPFLEFDMSVEGFGCLFLPSLAPQNAPGGSSE-------------------RVFPPPSGLSYSVWLCVERLDSPSQAHPVRLLTLVRRSTGSDRHLACLALSLLPR-DKAVLLCTREQLLQEMALKELVRHSQDGCVRFVTPE-LAQEGQWHHLVLVLNR-GVLKPSSASLYVDGQLAGNTKLSYIQATPGGLGSAGGPGAPPLVYGYVGTPPGRRRSSPLAWRVGPVHLMEEPLGHAAVATIFGLGVHHTGCMQAVL---QRATVSLVPEERLSFGLYPLSASLLTVAKIRKAYNKADSRAVAKQIGLSSNENVTPVMLLHNASGHLGGPSRTIGAAVIGNLGVRRSAARPVASSLQCVGGPALLLGLLAMAGDVEALYAATKALVCAVRASELAQREMERIRGYQLLAMLLKRKRSLLNTHSLHLALSLAGT---------VESGRER----DSLS-GLCLPAFRDLVTDLQIWFHSPYDL------------HLS-LLDHFVD--LLTESS--DVEELR-----RIMLGLQLVPKLLHVLKDHTL-PLSKATVMSIARLLSLLLQGFPSSHDMLWYGQFLASTLPTFSVSEKFVEQALPLGSTSVFRLSMEEDGAGLVSARNI-FLRNQLLEVLLDLLHTSAEKVMRRACEEMLRILGFDWLLLFVQGHLHPATVTVAMRILVSLLSNGGILRRFQEGSPGGGWLDLTQALVSGQTPTVLGFNVGRGPGGGVIPREINSEACLLPGFSVLLSCLPSHASLPQLYFFLLALFLNRPITSVPENVQ 884          

HSP 2 Score: 119.783 bits (299), Expect = 8.587e-27
Identity = 98/385 (25.45%), Postives = 176/385 (45.71%), Query Frame = 2
Query: 5903 CSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQH--VIDIILE-CDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGG---SYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTD-NIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLE 7030
            C EA   LL M+R  +NQ       E  +W+ +YP+T L+F  YLYH+     +V    +FL  L   ++P +          +   S  S      E+      N+   +   +      P+RKL++DF + I VD       S Q   ++D++LE    E  TQ   +++QT  + S+  H  + D LS Q       G   S+  + +++  F  RVVDK+WQ  +  +P ++ +++  LISQ ++R   ++ + LY   NR +L++LSR       ++   +         +   + + +  P N   +F  CL+H L+Q      I  +   + P   +T+ N+  +  Q+  +KL  ++       WQE+  +K+ ++E
Sbjct:  912 CLEAVLTLLAMLRSTVNQPWQA--EEEGSWLIEYPVTQLQFLQYLYHNVGGLANVWTHPEFLGSLAATIFPYN----------LRPHSEMSDTAVGTERASKDGGNVSEADYFFVHH----PSRKLVVDFLRTIAVDSLLQGNVSRQSPPLLDVLLENASPERATQSQQREYQTELLLSIMGHLQSADALSEQT----HAGHRVSFIQLVDSVTGF--RVVDKLWQGMFSREPRLVFNFIAELISQAKQRSQGLSLDGLYGCLNRAVLYQLSR------PRRWPAQQGVLQESLGQLLVHRNLLLGPGNYQPDFFACLLHCLLQ------IRMHRGEHFPTRAATEGNVCRSRAQL--VKLVRRV-------WQELIGSKRAVVE 1253          

HSP 3 Score: 115.161 bits (287), Expect = 2.762e-25
Identity = 49/106 (46.23%), Postives = 71/106 (66.98%), Query Frame = 2
Query: 7373 NHVSLEEARLWIPPHISVVKELMDYH------KNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPY 7672
            N    ++A +W+  HI+VV++L+DY       +    ++E  +   L ++W  +E+E+ RERG WGP VGS LDKWMLD  EGPCRMR+K++PNE+FY HY + PY
Sbjct: 1358 NRKQRKDASVWMFTHIAVVRDLVDYRYKQQQERRARGQRECSVARLLAAEWGRLEAEVTRERGPWGPPVGSRLDKWMLDPTEGPCRMRRKLMPNEHFYAHYAHYPY 1463          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: BPH1 (Protein homologous to Chediak-Higashi syndrome and Beige proteins; both of which are implicated in disease syndromes in human and mouse, respectively, due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting [Source:SGD;Acc:S000000628])

HSP 1 Score: 389.808 bits (1000), Expect = 4.421e-109
Identity = 204/479 (42.59%), Postives = 301/479 (62.84%), Query Frame = 2
Query: 8276 IEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYII-DGFTLLKTREIVEINNIPIDVHEPIV-----PSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAF-PKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSK--------------IEAGSTSIFS---NFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDD-PSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK 9637
            I  ++  ++ I  ++ C+ I GL++ EG+L+ G +Y Y + D +  L+ ++I++++ +  +  +  V     P    V+TF        K    +I  V KR +LL+ +A+E+   +  +   +F  K++++ +     ++   L  +   S   Q+ N +              I +  TS+FS   + +    ++++W +GEISNF YL+ +N LAGRS+NDL QYPVFPW++ADYES  LDL +P T+R L KPMGAQSE R  QF +RY       + ++ P+HYGTHYSSAMIV+ YL+R++PF + FL LQGG F  ADR+F S++  W SAS  N  D++EL PEFF+LP FL N N +D G  Q+G  + D++LPPWA GD + FI+ +REALE  YVSAHL+EWIDLIFGYKQ GD AV++VNVF+ L Y G V++ +IDD  +R A+ G I+NFGQ P Q+F++PHP K
Sbjct: 1363 ILRLLKDNDSIATIWNCSLIIGLEIKEGILIHGSNYLYFVSDYYFSLEDKKILKLSEVSQESRDMTVSLINGPDVKRVSTFLKHEVFVWKLL--DITFVTKRPFLLRDVAIELLFKERVSAFFSFYNKRVRDDVLRVLNKIPKHLPADPIFSSVLQEINDRGNSIVARNGIGKASIASKFTSVFSANNSLIDGFEISKKWVRGEISNFYYLLSINILAGRSFNDLTQYPVFPWVIADYESNVLDLENPKTYRDLSKPMGAQSEKRKLQFIERYEALASLENADSAPFHYGTHYSSAMIVSSYLIRLKPFVESFLLLQGGSFGPADRLFSSLERAWSSASSENTTDVRELTPEFFFLPEFLINVNSYDFGTDQSGKKVDDVVLPPWANGDPKVFIQKNREALESPYVSAHLHEWIDLIFGYKQKGDIAVKSVNVFNRLSYPGAVNLDNIDDENERRAITGIIHNFGQTPLQIFQEPHPEK 1839          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: VPS27 (Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p) [Source:SGD;Acc:S000005289])

HSP 1 Score: 66.6254 bits (161), Expect = 6.100e-11
Identity = 28/67 (41.79%), Postives = 43/67 (64.18%), Query Frame = 2
Query: 11162 GRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCF 11362
             ++ AD WI   +++ C+ C  +FSL  R+HHCR+CG VFC + S +   +  L +++PVRVC  CF
Sbjct:  164 SKTPAD-WI---DSDACMICSKKFSLLNRKHHCRSCGGVFCQEHSSNSIPLPDLGIYEPVRVCDSCF 226          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: TAF5 (Subunit (90 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification [Source:SGD;Acc:S000000402])

HSP 1 Score: 62.7734 bits (151), Expect = 9.275e-10
Identity = 84/357 (23.53%), Postives = 140/357 (39.22%), Query Frame = 2
Query: 9740 NMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQN-----KCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMP---DPYGDIMCVLCL-------------NERILITGGFSTVVRVWNMSVNASKPTASGS-------AGSRLTGGLAPALSLQA-------NLY------GHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICI-SEVTGMVASCAGTYLHLWSI-DGEELASVNTATGRSKQ-ILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEY 10678
            +++  +Q VKE ++A    I+ D      N   ++PS  +   QN      CL      R  A GF D  +++ + D   L          D   D  C   +             + + L++G     VR+W+M  + +  +  G        + S L    A A   Q        ++Y      GH+  V C++   +   + +GS D+TC MWD+     +R   GH APV +I +  +   +        +++W I  G+ L  +    G  K  I +++ S       GNV+I+GG D  VR+W L+               +EP A   +P    +  V  S N +  EY
Sbjct:  430 DLKLEIQKVKESRDA----IKLD------NLQLALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMR---GHGKNAIYSLSYSK-----EGNVLISGGADHTVRVWDLKKAT------------TEPSAEPDEPFIGYLGDVTASINQDIKEY 756          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: PIB1 (RING-type ubiquitin ligase of the endosomal and vacuolar membranes; binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain [Source:SGD;Acc:S000002721])

HSP 1 Score: 54.299 bits (129), Expect = 1.460e-7
Identity = 25/71 (35.21%), Postives = 35/71 (49.30%), Query Frame = 2
Query: 11183 WIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFK-----------PVRVCAKCF 11362
            W  DE A  C  CK  FS   RRHHCR CG +FC+ C+++    ++ R+             P R C +C+
Sbjct:   14 WQADEEAHSCFQCKTNFSFLVRRHHCRCCGRIFCSSCTENFVNYNKKRVHALQKKNSDVESPPYRTCNECY 84          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Match: FAB1 (1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis [Source:SGD;Acc:S000001915])

HSP 1 Score: 54.6842 bits (130), Expect = 3.655e-7
Identity = 21/62 (33.87%), Postives = 36/62 (58.06%), Query Frame = 2
Query: 11177 DHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCF 11362
            ++W++DE+++ C  C   F+   R+HHCR CG +FC+ C+    +  R      +RVC  C+
Sbjct:  235 EYWMKDESSKECFSCGKTFNTFRRKHHCRICGQIFCSSCTL-LIDGDRFGCHAKMRVCYNCY 295          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO33951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQQ4])

HSP 1 Score: 392.119 bits (1006), Expect = 6.457e-115
Identity = 262/747 (35.07%), Postives = 376/747 (50.33%), Query Frame = 2
Query: 8528 FSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKE----LKNAVGQIIQADL-----------NGTNSNAVGS--------VPSSVLAVEQNKCLIPPLYTRYVAWGFS--------------DGSLRVGNYDSDKLIKVYEMP-------DPYGDIMCVLCLNE--RILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPAL--SLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQL-------SGHAAPVAAICISEVTGMVASCA---GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQ--VPISTSFCSAD 10588
            ++  E+REVH RR+ L+  A+E FL D  N+ +   KK +N +Y K + +               +  +    G+ S  +  +    +T+RW K EISNF+YLM LNT+AGR+YNDL QYPVFPW+L DYES+ LDL++ + +R L KP+G  +  R+ + E RY+ ++DP+G    +HYGTHYS++  V FYL+R+EPFT   + L  G FD ADR FHSI   W+S   +  +D+KEL+PEFFY P FL N N FDLG  Q G  +  + LPPWA+    EF+  HR+ALE +YVS HL++WIDLIFGYKQ G+ AVEA NVF++  YEG VD+ +I +  +R A  G INNFGQ P QL   PHP  R+    +  +KQ   +    +S P   +F H +D ++     V +    L  A    +QA L             T S  +G+          S     E +  L      R VA  FS              D  L +     D  I+V+ +          + D +  L ++     L+TG   T  R+W +S                 GG A  +  S    LYGH   VTC+ ++   ++ VSGSRD TCI+    +  YLR L       S     V ++ +SE  G++ S        L  +SI+G  LA           ++ + +        G+ V+TGG  G + + SL  +   VPI++   + D
Sbjct:  265 WALAELREVHLRRHNLRRSALEFFLVDQTNYFINCSKKARNTVYKKIMSL---------------RPPNLYYMGARSP-AQLLKASGLTERWVKREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLVDYESKDLDLSNRAVYRDLSKPIGVLNPARVKEVEDRYKHFEDPTGTIAKFHYGTHYSNSANVLFYLLRVEPFTTLHVALHSGRFDCADRQFHSIPALWDSLF-NKASDVKELVPEFFYFPEFLENLNGFDLGRLQGGARVNHVTLPPWAR-TPEEFVHKHRQALESEYVSTHLHDWIDLIFGYKQRGEKAVEAHNVFYYCTYEGAVDLDAITNEAERIATEGMINNFGQTPSQLLTTPHPV-RMTQADAAAHKQ-KALEIAGTSKPLANVFEH-VDKLKAYFVVVTDSCDPLVFAAVPRVQARLLIHHGMPDCMVTVTRSGILGNQDWLPYSKTKSRPFTFELDPALSSVKLRRTVAGPFSPDVTVTSRHFAMTQDARLIITAGHWDNTIRVFSIKGKLQSRITAHSDTVTCLSIDRDGHHLMTGSRDTTCRLWLVS---------------HVGGWAADVDKSPLQTLYGHDHEVTCVVLSWELDMAVSGSRDGTCIVHTARKGQYLRTLRPMGNEPSSAPCRVTSLGLSEFGGIIVSSNTRDARALTHYSINGRLLAQ---ERALKDDVIDIEIC-------GDFVVTGGNSGRLGIRSLHSMNLLVPITSVSLAKD 965          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO45998 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRE1])

HSP 1 Score: 305.064 bits (780), Expect = 1.448e-86
Identity = 169/372 (45.43%), Postives = 229/372 (61.56%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPN-FLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK 9637
            K    +I  V KRRYLL+ + +E+F  D             +++Y         L LN+Q   S + Q  +       +  +   ++++T +W+ G I+NF YLMYLN+ + RS+NDL QYPVFPW++ADY S  LDL  P TFR L KP+GA + NRL+Q ++R R+  +P      + YG+HYS+   V +YLVR+ P  +  L LQGG FD  DR+F+SI++TWE+    + AD+KELIPEF+     FL N     LG KQ+   +GD+ LP WA  D  +FIR +REALEC YVS  LN WIDLIFGYKQ G+ A EA NVF++L YEG VD+ SI DP +R+++   I  FGQ PKQLF  PHP +
Sbjct:  174 KCKLSQISRVVKRRYLLRHVGIEIFSKDS------------SQMY---------LVLNSQ---SDRDQFYRELLKQPDVNLDDTEQENMTLKWQNGAITNFDYLMYLNSSSDRSFNDLTQYPVFPWVIADYTSSQLDLRDPLTFRDLAKPIGALNPNRLNQLKERCRDMTEPK-----FLYGSHYSTPGYVLYYLVRVAP--EFMLCLQGGKFDQPDRLFNSIQETWENVLTGH-ADVKELIPEFYQSSGEFLVNCQNLPLGMKQDKSNVGDVELPAWAT-DCEDFIRKNREALECPYVSERLNHWIDLIFGYKQRGEEAWEADNVFYYLTYEGAVDLDSITDPNERASLESQILEFGQTPKQLFTSPHPQR 512          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO30379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0Y3])

HSP 1 Score: 291.197 bits (744), Expect = 7.540e-85
Identity = 178/492 (36.18%), Postives = 261/492 (53.05%), Query Frame = 2
Query: 8858 GRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLL---------------IPISIINKQIDP--MAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSN----AVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL----------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVS 10237
            GR+Y DL QYPVFPWIL +YES+ LDL  P+ +R L KP+GA + NR  QF +RY  WD+ + + PP+HYGTHYS+      +L+R+EPF   FL LQGG FD   R F S++  W++ ++ + +D+KELIPE FYLP    N+N+F  G   +G+V+ D+ LP WA     +F+  HR ALE +YVS+ ++ WIDLIFG+KQ G  AV+A NVF HL YEG+VD+ SI D + R AV   I +FGQ P QL   PHP +                  +P++ +    D     P   +    + F  +++    S Q +++++     I Q  + GT S      +G  P          C +     R + A G+ D S +  + +S KL +       +G    V CL           + I+++G     V VW+ S    + TA+ ++       + P  S  A L GH + +TC+ V A+  L+VS
Sbjct:    1 GRTYCDLNQYPVFPWILTNYESDKLDLKDPNNYRDLTKPIGALNPNRHVQFLERYASWDE-NDDIPPFHYGTHYSTCGFTLAWLIRLEPFATQFLNLQGGKFDHPGRTFCSVQRAWQNCNR-DTSDVKELIPELFYLPEMFCNSNRFTFGVDDDGMVIDDVELPSWAN-TPEQFVTIHRAALESEYVSSQIHGWIDLIFGFKQRGPEAVKATNVFFHLTYEGSVDLDSISDTVMREAVEQQIKSFGQTPSQLLLDPHPPRVTQEMQVCIFLTFKVTENVPVTYVAAHTDQHITTPAVVTISCNQCF--SVNRWLASAQSLRDVR-----IEQDPMLGTPSGRQRRQLGE-PLDQTVTPSASCFVVTCDNRTIMACGYWDNSFKCFSTESGKLTQCV-----FGHSDVVTCLVYSRHQGLAGGDAIVVSGSRDATVLVWHWSERIQRVTAASNS-------VDP--SPLAILTGHEQPITCVDVNAALGLVVS 467          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO46742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNV7])

HSP 1 Score: 246.128 bits (627), Expect = 7.787e-70
Identity = 161/489 (32.92%), Postives = 244/489 (49.90%), Query Frame = 2
Query: 9155 GHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVL---------AVEQNKCLIPPLYTRYVAWGFSDGSLRV---GNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAG--------TYLHLWSIDGEELA------SVNTAT-GRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
            G+FD  DR FHS+  TW  +S  +  D+KELIPEFF+LP FL N   FD G +QNGV + D+ LPPWAK + R FI  HR+ALE D VS HL+ WIDLIFG+KQ G  AVEA+NVFH   Y G VDI SI DP+   A+   I  +GQ P QLF  PH  +    P ++       ++ L   A         ++    S       +N +   I   L G   NA+ S  ++ L         A++  + L+  +    ++W   +G L V   G   S  L+   + PD     +    ++ + L  G  +  + V  +  N +        G+R+             LYGH +A+TCL V   ++++VS  +D   I+WDL R+ Y+R L+ H+  V A+ +S  +G +A+ +         + L+LW+++G  +A      ++N     R+ + L+V           NV+ TG ++G +R+WS
Sbjct:    2 GNFDQPDRTFHSLATTWRLSSYQSPTDVKELIPEFFFLPEFLENFEGFDFGFRQNGVRVMDVSLPPWAKNNPRLFILIHRQALETDIVSQHLHNWIDLIFGFKQTGKDAVEALNVFHPATYFG-VDINSITDPISNKALKTMIETYGQTPTQLFTYPHSPRVTRKPQALSAADTASVSSLKLDAEVASFTGTFINRFTSSFSS----ENTIVGSITDTLAGGRYNAIISHSNTTLITMYQKADAAIDSERLLLSAV----LSWAAMNGQLDVYHGGTSASPMLLMGTKTPDK----VTRCAVSRKSLFIGSSTGALSVIPVKYNQATDCGIEVQGTRV------------RLYGHTQAITCLHVCHEFSVVVSAGQDGRAIIWDLNRLSYVRSLT-HSNAVTAVSVSRTSGDIATVSNAESVGEEESDLYLWTVNGRPIAHKTCEITINCLDFSRAPEGLSV-----------NVIATGLSNGAIRLWS 453          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Match: EDO29546 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3B8])

HSP 1 Score: 120.939 bits (302), Expect = 1.460e-31
Identity = 55/119 (46.22%), Postives = 77/119 (64.71%), Query Frame = 2
Query: 8798 RWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQG 9154
            RW  G +SNF+YL  LN +AGR+ NDLMQYPVFP++L+D+ SE LDL  P T R L KP+  Q+     ++++ YR+  +      P HY +HYS++  V  +LVR+ PFT   L+ QG
Sbjct:    1 RWRAGTLSNFEYLTELNKMAGRTCNDLMQYPVFPFVLSDFTSEVLDLNDPKTLRDLTKPIAVQNPIMEAKYKEYYRQQGESDPAAAPCHYSSHYSNSGTVLHFLVRLPPFTNMLLQYQG 119          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: wdfy3 (WD repeat and FYVE domain containing 3 [Source:NCBI gene;Acc:101161316])

HSP 1 Score: 1213.75 bits (3139), Expect = 0.000e+0
Identity = 826/2676 (30.87%), Postives = 1365/2676 (51.01%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGG-LKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDA---GISDSVNNEQDEXXXXXXXXXXXXIS-------NCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPV-------------PPSSI------------------NNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCC--------------QPITINKD-DINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXX---XXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENP--------IGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA---EFKN--TIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAA---LREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEK--CGNVINNIRNTEMITLESLNSL---PARKLIMDFFKMIIVDYF-SLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQN--LPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQ--ITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGY--------STWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKI------QXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYY 7768
            MN V+RI+    +   +     +D    L  L+ LF++      +    + ++ LY ++P+F+++F   P   + E+F D+  F + VS LMV EI++RA+N+ TE AS AIVQ+L+ N ++    E ++GW+LL+ + +L+      ++CM T S+PST VKCLY+FFDLP+      Q +                   P    RR +L   F Q++ ++C + +  EEL +K+DL+LLF A+ SWCP HN  WR++A +VL TI+ +GLS + +++I+ K+ ++ C++N+ +   L  +EIV++F  L   L++SS V+Q LLDDFR  QGY+ + + +++LE+   +E  +D+++ L+ L+  L T G  EL+P   L+    + + GF LP P  K  ++RN  AF VLQ+ FL A+T  L   +L+AI  IY  DPANYFILE Q+T   F+E++ K     Q +   L++ +V +LNYVP KE+  +S+++K+      +   V+  ++L  H+ +F +VL+++G+LE+ VN LH YA  LK          +D  NN   E    L   +   ++         + N  LFR+ GG+ CV ++V + + +  AL  I+ L LS   ++DM   LGL+ S     L LK  +L +L  VL+ESHR R VFRKV  FV     LV +E       +  W+ + + ++ E +  + S LT A++ EP+N  +F   + Y  L +A+R LGCF     L     + GV   N    Q    +  +      +SV                  L  CS+          +  +++  A + FD+                 ++   ++  + +P+P   P              PP+ I                  ++  ++++HP AV++++ L+P+I  D +Q  H ++LQ+ +   L  L + +RN Q++CE+  +   +L     A+ +E+HPLH     +FERLA+Q + P  +R+FLRL +PL C              +P +++ D D+      S   + P +      + NG    +    S ++   G  + LTRVK L+ +TT                    D      A+ P+FVE +M  EGFGCLFLP  +    ++  ++       +  ++ G+G GER+FPP  G S+STW CV++FSS    HP+RLL++ R    S +   CL ++ +++ + ++ VSTKEE+      E+  E++  E +   A F C  L+ E  W HLVL   + GM+K+S  + +++GQL++T KL+YI      S  +   ++++VY YIGT P   ++S+L WR GP  F+EE L A+  + I  LGPNY+G+FQ   L  ++         + +LV EEKV FSL A+++S  T+ +I K YN+LD   +A+QL +   E ++P+++IHNAAGHL+G  R++GA ++GY G+R F P P+   +  VGG+  +LG++AMA+D E LYA VK +   +  N    KE+E   GY+L++ LLKKKR LL+S I  L   L G+ D   +   I                 N   F +++CD  +WLH                 H+S  F+  ++   +++SSE   K CR       L D  L+ +   L++      L+      +S ++ L++     P DL RFGQF+  TL      E  + +  NN+  +++    +F    +  LI +RN     +L++L  +    T   +  EEL++ LGFDW+L+FM+  +H STV +A+  LV LLS    + +F++G+   GWL  TD VL  + G +L  N          LREIN D+CH PGF  LQ+LLP H  +P++YF+L+AL L   +  +PD+L+          +  N      ++ + F+ +S+  F+FG             + SG   G I                         +C+EAA +LL M+R MLN        E  +W+R+YP+TL++FF YLYH+  +   +   ++FL  L  A++P +   ++   + ++    E+   TE  K   G+   N   +E   + S  SL   PA+K + DF +++I+D   + P +    ++D++LE   E +T+   K+FQ+  ++ + EH +A D+L G++  LPL  GGSY  + NN++YF  RVVDK+WQ  +  D  +++ ++ +LI Q ++R   ++ +++Y   NR +L++L R        K + + +  L      T   + +  P N D +FV CL H  I L +G N+ G+        +TW+ P  I  +N  D        +  + +      +W E+  +K+Q+LE+ FK+      +   ++ +    +E+  LK+W +++  E    +     R     P +  + S +++G  +S+    + + K N +++NS                                 S +E   W+  HI+VV++L+      + +++   + Y+  +W S+E EL RERGLWGP +GS LDK++L+  EGPCRMRKKM+ N+ FY HYPY P      +   N  Q  +  +++ A S D + YY
Sbjct:    1 MNMVKRIMGRPRQDECSP----QDNALGLMHLRRLFSELCHPPRHMTQKEQEEKLYMMLPVFNRVFGNAPPSSMTEKFSDLLQFTTQVSRLMVTEIRRRASNKSTEAASRAIVQFLEVNQSE----ETSRGWMLLSTINLLASSGQKTVDCMTTMSVPSTLVKCLYLFFDLPHMTEGHPQPEL------------------PL-ADRRALLQKVFVQIMVKLCTFVSPAEELAQKDDLQLLFSAITSWCPPHNLPWRRSAGEVLNTISRHGLSVNVVKYIHEKECLATCVQNMQQSDDLSPLEIVEMFAGLSCFLKDSSGVSQTLLDDFRMCQGYSFLCDLMLRLEQGKEDEP-KDALKDLVNLVTCLCTYGVTELKPA-GLTTGAPFLLPGFVLPQPTGKGHTVRNIQAFAVLQNAFLRAKTSRLACMLLDAIGNIYAADPANYFILESQHTLSQFAERVAKLP-EAQVKYFELLEFVVFSLNYVPCKELFGVSMLLKSSTSHACSITAVRTLLKLARHDPVFSDVLREVGLLEVLVNLLHKYAALLKDPASFLSFCSADCKNNTVAEEQKQLAWLVMETLTVLLQGSNTTNTNAALFREFGGARCVHNIVKYRQCREHALLIIQQLVLSPSGDDDMGTLLGLMHSAPPSELQLKTDILRALLAVLRESHRTRTVFRKVGGFVYVTSLLVAMERSLCQPPQHGWERVNQNQVFELLHTVFSTLTAAMRYEPANSYFFRTEIQYEKLADAVRLLGCFSDTKKL----GATGVFPSNAQPFQRLLEDEAAPAGCAGDSVC---------------PTLKHCSK----------LFIYLHKMATDSFDS--------------RAEHMPPCLTHETSLPSPWGTPALTRKRHGYYGTTGPPAPIKALTDLKVHLSNPSLTGSSSSDTVVIHPGAVLAMVDLLPSITSD-SQPEHALDLQLAVANILQLLVNSERNQQVLCEAC-LHQRMLQRCSQALADEDHPLHPPLQRMFERLASQALQPVVLREFLRLGNPLNCGAWDKKLLKQYRVHKPSSLSYDTDMRNGMTMSMEGFGPDSVFATPAEDNG---QYRISRSLVRSAEGSTVPLTRVKCLVSMTTPH------------------DIHLHGSAETPAFVEFDMSLEGFGCLFLP--SLAPHNAPTNNANTSGVSDGAVLSGMGTGERLFPPPSGLSYSTWFCVERFSSAPQAHPVRLLTMVRRATSSEQHYVCLAVA-LSTKDRLLTVSTKEELLQTHSDESSEEASFYEILPCCARFRCADLIAEGQWHHLVLVMSK-GMLKNSMATLYIDGQLVNTVKLHYIHSTPGGSGSTNPPVVSTVYGYIGTPPAQRQLSSLVWRLGPSIFLEEVLPATSAAAIYELGPNYVGSFQAVYLPCKDSRAEPSPATLVALVPEEKVSFSLSAHSVSALTVAKIRKAYNKLDSKAVAKQLAVSSHENATPVKLIHNAAGHLNGPARTIGAAVVGYLGVRAFVPKPVATTLQYVGGAAAILGLVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLKKKRSLLNSHILHLTFSLVGTVDSGHETSIIP----------------NSTAFQDLLCDFEVWLHAPYEL------------HLS-LFEHFIE--LLTESSEA-AKNCR------LLRDFQLVPK---LLLTLRDTSLSQPTVAAISNVLSLLLQGFPNPYDLLRFGQFLSSTLPTFAVCEKFVVMEINNEEKIDAGNDDDFGGLLSASLILLRNRLLDNLLRLLFITKEKCTVNAQACEELVRTLGFDWLLMFMEEHLHSSTVTVALWILVVLLSNQSILNRFKEGLSGGGWLDHTDAVLTNKIGTVLGFNVGRSAGGRSTLREINRDACHFPGFPVLQTLLPKHTNVPELYFLLMALFLQQPVNMLPDSLQ----------VHVNITPVTSSSWTHFDLDSLWTFIFG-----------IPASSGTVVGSI-----------------------HSVCTEAAFLLLAMLRSMLNLPWQ--SEEEGSWLREYPVTLMQFFRYLYHNVPDLSPMWHSAEFLCALAAAVFPFN---IRPYSEMVSDLDDEAGSPTEEFKAFAGDSGMNRSQSEYCNVGSKTSLTNHPAKKYVFDFMRVLIMDNLCTTPASKQTPIVDLLLEASPERSTRTQQKEFQSNILDGVMEHLLAADVLLGEDASLPLSSGGSYQILVNNVFYFTQRVVDKLWQGMFNKDSKLVVDFIVQLIGQAKRRSQGLSLDAIYHCLNRTVLYQLCR------PHKTVAQQVALLEALRVLTVNRNLVLGPGNHDQDFVACLAHCFICLHSGSNVEGFGLEAEARMTTWHVP--ILAENEPDAVQSHDVSEGRQLLLKAVNRVWTELMHSKRQMLEDIFKVSLPCNDRGHVDIATARSALEEHALKSWQNHLAHEKKCIS-----RGEAVAPATQSKLSRVSSGFGLSKLTGVRRNKKENSLNKNS--------------------------------PSAQETFQWMFTHIAVVRDLVAMQYKEYQERQQNALKYVTEEWASIEYELLRERGLWGPPIGSHLDKFVLEMTEGPCRMRKKMVRNDMFYIHYPYIP------ETTTNSTQ--KPLRYRRAISYDSKEYY 2433          

HSP 2 Score: 1151.73 bits (2978), Expect = 0.000e+0
Identity = 555/1058 (52.46%), Postives = 737/1058 (69.66%), Query Frame = 2
Query: 8255 QWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSF---------CSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRS-NMAISIDNKDKSSDEL--DEE--YVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQS 11386
            Q     ++  ++   EKI  M+RCAR+QGLD  EGLLLFG+ +FY+IDG+T+  +REI +I+ +P ++HE I+P          +R  S  F++ +I+EVHKRRYLLQP+AVEVF  DGRN+LLAF K ++NK+Y +F+ V  SL  ++  S+SGQ+ N+ +E GS  + S  +GEKSVTQRWE+GEISNFQYLM+LNTLAGRSYNDLMQYPVFPWILADY+SE +DL +P +FR L KPMGAQ+++RL Q++KRY++W+DP+GETP YHYGTHYSSAMIVA YLVRMEPFTQ FL+LQGGHFDLADRMFHS+++ W SAS+HNMAD+KELIPEFFYLP FL N+N FDLG KQNG  LGD+LLP WAKGD REFIR HREALECDYVSAHL+EWIDLIFGYKQ G  AVEAVNVFHHLFYEG VDIY+I+DPLK +A IGFINNFGQIPKQLFKKPHP KR      + +K     A +  +  ++++F+H+LDN+ PSL PVKELK  VGQI+  D               +LAVEQNK L+PP +T+  AWG++D S R+ NY+SDK + VYE    +G I+C +C N ++++TGG ST + VW           +G++  R     A +L+L+  L GH +AVTCL  +++Y+++VSGSRDRTCI+WDL ++ ++ QL GH AP++A+CI+E+TG + SCAGTY+H+WSI+G  ++S NT TGRS+QIL   +S M +WD  NV++TG +DGVVR W +E++QVP + +          C  +        S        S+ + S    D          S     + Q+     S +M    D+  + SD L  DE+  +V +  +E  +   +  +  +   +     + S V++                +LR G+ W+RQL+FRSKLTMHTA++R DNA+P+ ISSLAIS+DH  I VGD RGRVF WSV ++PGRS ADHW++DE  + C  C +RFSLTERRHHCRNCG +FC +CS++++EI RL++  PVRVC  C+Y++  ++S
Sbjct: 2511 QRTENTSLLRLLEEGEKIQHMYRCARVQGLDTSEGLLLFGKEHFYVIDGYTMTVSREIRDIDTLPPNLHEAIIPRGARQGQSQLKRTCS-IFAYEDIKEVHKRRYLLQPMAVEVFSADGRNYLLAFQKGVRNKVYQRFLAVVPSLA-DSSESVSGQRPNTSVEQGS-GLLSTLVGEKSVTQRWERGEISNFQYLMHLNTLAGRSYNDLMQYPVFPWILADYDSEEVDLNNPKSFRNLAKPMGAQTDDRLTQYKKRYKDWEDPNGETPAYHYGTHYSSAMIVASYLVRMEPFTQIFLRLQGGHFDLADRMFHSVREAWLSASKHNMADVKELIPEFFYLPEFLLNSNNFDLGAKQNGTKLGDVLLPSWAKGDPREFIRVHREALECDYVSAHLHEWIDLIFGYKQQGPPAVEAVNVFHHLFYEGQVDIYNINDPLKETATIGFINNFGQIPKQLFKKPHPPKR------VRSKANGDAAGVPPNFNSDKIFFHHLDNLRPSLAPVKELKEPVGQIVCTD-------------KGILAVEQNKVLVPPAWTKTFAWGYADLSCRLANYESDKALVVYECLSEWGQILCAICPNPKLILTGGTSTAICVWE----------TGTSKER-----AKSLTLKQALLGHTDAVTCLTASSAYHIVVSGSRDRTCIIWDLNKLSFVTQLRGHRAPISALCINELTGDIVSCAGTYIHVWSINGSPISSANTFTGRSQQILCCCVSEMNEWDTQNVIVTGHSDGVVRFWRMEFLQVPETPAPEPVEPDVPDCCGENHNAADDDSSESDGDEPSLSQESRPPRDPSTGGGSQPGSAVHRPRGQSGRAGASWSMDSGSDDSHRWSDTLSIDEKDGFVFVNYSEGQTKGPHPHLAPQGQSSGPHSLHPSSVEAR------------TYNQLRAGYRWERQLVFRSKLTMHTAFDRKDNAHPAEISSLAISKDHSKILVGDGRGRVFSWSVSEQPGRSAADHWVKDELVDSCSACTVRFSLTERRHHCRNCGQLFCQRCSRYQSEIRRLKISSPVRVCQNCYYNLQHERS 3519          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: lyst (lysosomal trafficking regulator [Source:NCBI gene;Acc:101170120])

HSP 1 Score: 416.772 bits (1070), Expect = 8.125e-116
Identity = 261/796 (32.79%), Postives = 403/796 (50.63%), Query Frame = 2
Query: 8291 GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPK-KMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYR----------EWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQP-----VKELK--NAVGQ-------IIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTR----------------YVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCA-----GTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS 10540
             + E I F  RC  +       G LL G+S  Y ++             +N        I+       +F+        +++ EI+EVHKR + L+  AVE+FL +GR  LLAF   K ++ ++               H+I      + +E G+ +         ++TQ W  G+I+NF+YL +LN  AGRS+NDLMQYPVFP++L+DY SETLDL   + +R L KP+  QS+ +  ++   YR            DDP     PYHYG+HYS++  V  +LVRM PFT+ FL  Q   FD+ DR FHS+  TW  +S  +M D+KELIPEFFYLP FL N   FD G +QNG  +  + LPPWA+ D R F+  HR+ALE D+VS  L +WIDL+FG KQ G AAV+A+NVFH   Y G +D+ +++DP++R A+   I  +GQ P+QLF   H ++    P  ++  ++    P A     +  F    +  +  + P     +K +K    VG        +  +  +G    ++ ++P+  +    +K  +  +Y++                 ++WG+ D  LR+ +  S+  I   +    +    C    +   L TG    V+  ++    +S P+                +  Q +LYGH   VT L V   Y++L+S S D TCI+WDL R+CY++ L+GH +PV A+  SE TG +A+       G+ L LW+++G+ +  V+      + I ++  S   +    NV+  G  +GVVR+WS
Sbjct: 3040 ATSESIRFTRRCVSVAPSRETAGELLLGKSGMYFVE-------------DNAADAQDSQILHGETEAPSFS--------WTYEEIKEVHKRWWQLRDNAVEIFLTNGRTLLLAFDNTKFRDDVF---------------HNILTSDLPNLLEYGNIT---------ALTQLWGSGQITNFEYLTHLNKHAGRSFNDLMQYPVFPFVLSDYTSETLDLQEANIYRNLSKPIAVQSKEKEDRYVDNYRYLEEEYKKGIREDDPMPPVQPYHYGSHYSNSGTVLHFLVRMPPFTKMFLAYQDQSFDIPDRTFHSMNTTWRLSSYESMTDVKELIPEFFYLPEFLVNREGFDFGVRQNGERVNHVNLPPWARNDPRLFVLIHRQALESDHVSQTLCQWIDLVFGLKQKGRAAVQAINVFHPATYFG-MDVSAVEDPVQRRALETMIKTYGQTPRQLFSASHMSRT--GPKLMMEGEL----PAAMGLLVQLAFRETREQAKEVVCPSPLPWIKGMKWGEFVGSPSAPDPVVCFSQPHGERFGSLLALPTRAICGLYSKFCLMMIYSKEQGVRSMHSTDIQWSAILSWGYGDNILRLKSKQSEPPINFIQCSQLHQVSSCAWVPDGCQLFTGSKCGVITAYSNRFTSSTPSEM-------------EVESQVHLYGHTGEVTNLVVCKPYSILISVSCDGTCIIWDLNRLCYVQSLTGHKSPVTAVAASETTGDIATVCHSEGGGSDLRLWTVNGDLIGHVHC----RETICSLAFSNQPEGVSVNVIAGGLENGVVRLWS 3766          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: lrba (LPS responsive beige-like anchor protein [Source:NCBI gene;Acc:101175296])

HSP 1 Score: 368.622 bits (945), Expect = 1.935e-101
Identity = 225/632 (35.60%), Postives = 335/632 (53.01%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLI-------------------------PISIINKQIDPMAPLAS--SAPAERLFYHN-LDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCL--------NERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSG 10306
            K+ F EIR V  RRYLLQ  A+EVF+ +    L  FP        A   +V   L      +  G  Q  +I   S +         ++TQRW++ EISNF+YLM+LNT++GR+YNDL QYPVFPW++ +Y+SE LDLT PS FR L KP+GA +  R   F  RY  W+D   + P +HYGTHYS++     +L+R+EPFT  FL  QGG FD ADR F S+   W +  Q + +D+KELIPEF+YLP    N+N ++LG  ++G V+ +++LPPWAK    EF+R +R ALE ++VS  L++WIDLIFGYKQ G  A  A+NV++++ YEG V++ SI+DP+ R AV   I +FGQ P QL  +PHP +   +                         P++ +     P    A+  +  A RLF  N    +    Q   +L   +  +I +++ G +   +  +    + +  ++C +     R++   GF D S RV + DS KL ++      +G    V CL         +  +++G     + +W  +    K  + G      T G     + +A L GH   VTC +V A   L++SG ++  C++  + G +  LR L G
Sbjct: 1976 KWLFTEIRAVFSRRYLLQNTALEVFMANRTAVLFNFPDA------ATVKKVVHCLPRVGVGTSFGLPQTRRI---SLATPKQLFKASNMTQRWQRREISNFEYLMFLNTISGRTYNDLNQYPVFPWVITNYDSEELDLTLPSNFRDLSKPIGALNPKRAAFFSDRYESWED--DQVPKFHYGTHYSTSSFTLMWLLRIEPFTTFFLNFQGGKFDHADRTFSSVSRAWRNC-QRDTSDVKELIPEFYYLPEMFVNSNNYNLGVMEDGTVVSNVVLPPWAKS-PEEFVRINRLALESEFVSCQLHQWIDLIFGYKQQGPEATRALNVYYYVTYEGAVNLSSINDPMLREAVESQIRSFGQTPCQLLIEPHPPRSSAMQVTPLMFTEQMQQDVIMVLKFPSNSPVTYVAANTQPGLTSAAIITVTANRLFAVNKWHGLTGEAQQQYQLPVEIDPLIASNV-GAHRRQISDLLDQSIQI-SSQCFVITADNRFILLCGFWDKSFRVYSTDSGKLTQIV-----FGHRDVVTCLARSESYIGGDCYILSGSRDATLLLWYWN---GKLCSIGE-----TPGSESFTTPRAILTGHDCEVTCASVCAELGLVISGCKEGPCLIHSMNGDL--LRTLEG 2577          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: nbeal2 (neurobeachin like 2 [Source:NCBI gene;Acc:101163272])

HSP 1 Score: 353.984 bits (907), Expect = 6.874e-97
Identity = 181/382 (47.38%), Postives = 246/382 (64.40%), Query Frame = 2
Query: 8498 FNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQ-NGVVLGDILLPPWAKGDSRE-FIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTK 9637
            F+ +R +S      ++REVH RRY L+  A+E+F  D  ++ + F KK++NK+Y++ +               G +  +    GS S     +    +TQ+W   EISNF+YLM LNT+AGR+YNDL QYPVFPW+L DY S TLDL+ PS FR L KP+G  +        ++Y  ++DP+G    +HYGTHYS+A  V  Y++RMEPFT   ++LQ G FD+ADR FHS+   W+ A   + AD+KELIPEFFY P FL N N FDLG  Q +   + D+ LP WA   SRE FIR HR+ALE ++VS+HL+EWIDLIFG KQ G+ AV A+NVF++  YEG VD+ +I +  +R A  G I+NFGQ P QL K+PHP++
Sbjct: 2035 FDFKRPLS------QLREVHLRRYNLRRSALELFFIDQSHYFINFKKKVRNKVYSRIL---------------GLRPPNLFYFGSRSP-QELLKASGLTQKWVYREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSPTLDLSDPSIFRDLSKPIGVVNPRHAQNVREKYESFEDPTGNIDKFHYGTHYSNAAGVMHYMIRMEPFTTLHIQLQSGRFDVADRQFHSVAAAWQ-ARMESPADVKELIPEFFYFPEFLQNMNGFDLGRLQISQEAVTDVELPRWAT--SREDFIRKHRKALESEHVSSHLHEWIDLIFGCKQRGEEAVNALNVFYYCTYEGAVDLDAIANETERKAYEGIISNFGQTPCQLLKEPHPSR 2391          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Match: nbeab (neurobeachin [Source:NCBI gene;Acc:101155372])

HSP 1 Score: 335.495 bits (859), Expect = 1.629e-91
Identity = 244/730 (33.42%), Postives = 366/730 (50.14%), Query Frame = 2
Query: 8504 HRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLI------------------------------PISIINKQIDP--MAPLASSAPAERLF----YHNLDNMEP----SLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYV-AWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGG-------LAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDL-GRMCYLRQLSGHAAPVAAICI---SEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMW 10537
            H   +  K+ F EIR V  R YLLQ  A+EVF+ +  + +   P +      A    V  SL      +  G  Q  +I   S +         ++TQRW++ EISNF+YLM+LNT+AGR+YNDL QYPVFPW+L +Y+SE LDLT P  FR L KP+GA +  R   + +RY  W+D   +TP  HY +HYSS      +LVR+EPFT  +L      FD  DR F SI  +W S  Q + +D+KELIPEF+YLP    N++ ++LG +++G  + D+ LP WAK    +F+R +R ALE ++VS  L++WIDLIFGYKQ G  AV A+NVFHHL YEG+V++  I D   R A    I +FGQ P QL  +PHP +   +                              P++ +     P    P   +    RLF    +HN   +      SL     L   +  +I A+  G+N + +  +    + +  + C +     RY+    F D S RV + ++ KL ++      +G    V CL       GG   +V   + S +A+      S    +  G       L    + +A L GH + V C++V A   L++SG+++  C++  + G +  LR L G A  +    I   SE   ++    G + + +SI+G+ LA +        +I   T + ++  D G+ ++TGG +GVV +W
Sbjct: 1559 HTEGLHGKWMFSEIRAVFSRCYLLQNTALEVFMANRTSVMFNLPDQ------ATVKNVVHSLPRVGVGTSYGLPQARRI---SLATPRQLFKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYDSEELDLTLPRNFRDLSKPVGALNPKRAAFYGERYGTWED--DQTPSCHYTSHYSSTSTTLHWLVRIEPFTTFYLCSNKNKFDHPDRTFSSIARSWRSC-QRDTSDVKELIPEFYYLPEMFVNSSNYNLGMREDGSRISDVELPAWAK-KPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHHLTYEGSVNLDGIGDLSLRQATEAHIQSFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHNTVGLRGAPGYSLDQAHHLPIEMDSVI-ANNTGSNKHQITDLVDQSIRITTH-CFVVTADNRYILVCSFWDKSFRVYSSETGKLTQIV-----FGHWDVVTCLARSESYIGGDCYIV---SGSRDATLLLWYWSGRHHIIDGHYHFIFLLYLCFAPRAVLTGHDQEVVCVSVCAELGLVISGAKEGPCLVHTITGDL--LRALEGPAYCLCPRLISVSSEGHCIIYYERGHFCN-FSINGKLLAQM--------EIKDSTRAIILSSD-GHNLVTGGDNGVVEVW 2253          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000039846.1 (SMESG000039846.1)

HSP 1 Score: 7291.81 bits (18918), Expect = 0.000e+0
Identity = 3763/3783 (99.47%), Postives = 3767/3783 (99.58%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389
            MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSDSKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISL+HLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGGFSFSTWICVQKFSS+ATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTD+VLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENME             FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESI FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQI QESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQIS+KLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSAD SEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS
Sbjct:    1 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSDSKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLLHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGGFSFSTWICVQKFSSMATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDVVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENME-------------FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESISFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQIIQESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISVKLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADLSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 3770          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000039846.1 (SMESG000039846.1)

HSP 1 Score: 7263.69 bits (18845), Expect = 0.000e+0
Identity = 3751/3783 (99.15%), Postives = 3755/3783 (99.26%), Query Frame = 2
Query:   41 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAXXXXXXXXXXXXXSNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDEXXXXXXXXXXXXISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNXXXXXXXXXXXXXXXXHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRVFPPTGGFSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYXXXXXXXXXXXXPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFXXXXXXXXXXXXIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCIXXXXXXXXXXXXXXRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFXXXXXXXXXXXXXETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389
            MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSDSKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISL+HLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGGFSFSTWICVQKFSS+ATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTD+VLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLK                         FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESI FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQI QESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQIS+KLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSAD SEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS
Sbjct:    1 MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISDHDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRATNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIECMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKYDPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCPSHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKSIEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISNETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNKNESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQNTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTCNVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKEQDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSLVNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLESLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDVDLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNGNYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSDSKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLLHLIPAIRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQFAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINKDDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISLTRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMCYEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGGFSFSTWICVQKFSSMATTHPIRLLSLARSLQGSNEFISCLNISIINSPNHVILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFHRPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIGTTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILDYENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLHPKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCVGGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLISFLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKSFNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYVSDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLSKLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESAEFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWILLFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDVVLQKRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLK-------------------------FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESISFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQIIQESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISVKLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADLSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 3758          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000039846.1 (SMESG000039846.1)

HSP 1 Score: 3875.86 bits (10050), Expect = 0.000e+0
Identity = 1958/1977 (99.04%), Postives = 1961/1977 (99.19%), Query Frame = 2
Query: 5459 LMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQXXXXXXXXXXXXXXEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQITQESLYRSFNRLILFRLSRRIAEXXXXXXXXXXXXXXXXXSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQXXXXXXXXXXXXEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISIKLNRMSRNSVLGRLXXXXXXXXXXXXXXXXXXXXXXRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPXXXXXXXXXXXXXXXTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 11389
            ++DNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENME             FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESI FTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQI QESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQIS+KLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSAD SEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS
Sbjct:   25 IVDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFMLIALLLGNKIKNIPDNLKETNPKTWLENME-------------FEFESVCNFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKKSVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLYHSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESISFTENEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSYQHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPPGGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQIIQESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGIFNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQMKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQHQISVKLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLEEARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRERGLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCDNNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMNDSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDNKIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRSESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMIGSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEINNIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVGQIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLRVGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVNASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSGSRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLWSIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWSLEYVQVPISTSFCSADLSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEEIWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINSDLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHWQRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFFWSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNKCSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS 1988          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000017089.1 (SMESG000017089.1)

HSP 1 Score: 355.91 bits (912), Expect = 1.198e-97
Identity = 174/378 (46.03%), Postives = 246/378 (65.08%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPIS 9658
            K+ F EIR +  R++L + IA+E+F+ +    + AFP +   +   K I V   + +  ++ +S  +++S          SN      +TQRW++ EISNF YLMYLNT+AGR+YNDL QYP+FPW+LA+YESET+DL+SPS +R L  P+GA + +R   F+ R++ WDD S     +HYGTHYS+A  V  YLVR+EPFT  FL LQ G FD ADR FHS+  TW++  Q + +D+KELIPEFFYLP    N+N +  G  ++G ++ D++LP WAK    +F+R +R+ALE + VS  L+ WIDLIFGYKQ G  A+ + NVF +L YEG+V+   I DP+ R A+   I +FGQ P QL  +PHP +   + +S
Sbjct: 2026 KWHFSEIRAIFSRKFLHKNIALEIFVANRMAVMFAFPDQ---ETVRKVIYVLPRVGIGIKYCVSQHRKSSLASPRQIFKLSN------MTQRWQQREISNFDYLMYLNTIAGRTYNDLNQYPIFPWVLANYESETIDLSSPSNYRDLSSPIGALNPSRKKFFDNRFKNWDDDSQSA--FHYGTHYSTAAFVLNYLVRVEPFTTLFLNLQSGKFDHADRTFHSVAQTWKNC-QRDTSDVKELIPEFFYLPEMFTNSNDYRFGKSEDGNIVDDVILPKWAKT-PEDFVRINRQALESELVSCQLHHWIDLIFGYKQRGPEAIRSTNVFCYLTYEGSVNWDEIKDPMIRQALEDQIRSFGQTPSQLVTEPHPPRNSALHVS 2390          
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Match: SMESG000017089.1 (SMESG000017089.1)

HSP 1 Score: 355.91 bits (912), Expect = 1.307e-97
Identity = 174/378 (46.03%), Postives = 246/378 (65.08%), Query Frame = 2
Query: 8525 KFSFGEIREVHKRRYLLQPIAVEVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKIEAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYPVFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDPSGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHSIKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDILLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEAVNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKRLLIPIS 9658
            K+ F EIR +  R++L + IA+E+F+ +    + AFP +   +   K I V   + +  ++ +S  +++S          SN      +TQRW++ EISNF YLMYLNT+AGR+YNDL QYP+FPW+LA+YESET+DL+SPS +R L  P+GA + +R   F+ R++ WDD S     +HYGTHYS+A  V  YLVR+EPFT  FL LQ G FD ADR FHS+  TW++  Q + +D+KELIPEFFYLP    N+N +  G  ++G ++ D++LP WAK    +F+R +R+ALE + VS  L+ WIDLIFGYKQ G  A+ + NVF +L YEG+V+   I DP+ R A+   I +FGQ P QL  +PHP +   + +S
Sbjct: 2026 KWHFSEIRAIFSRKFLHKNIALEIFVANRMAVMFAFPDQ---ETVRKVIYVLPRVGIGIKYCVSQHRKSSLASPRQIFKLSN------MTQRWQQREISNFDYLMYLNTIAGRTYNDLNQYPIFPWVLANYESETIDLSSPSNYRDLSSPIGALNPSRKKFFDNRFKNWDDDSQSA--FHYGTHYSTAAFVLNYLVRVEPFTTLFLNLQSGKFDHADRTFHSVAQTWKNC-QRDTSDVKELIPEFFYLPEMFTNSNDYRFGKSEDGNIVDDVILPKWAKT-PEDFVRINRQALESELVSCQLHHWIDLIFGYKQRGPEAIRSTNVFCYLTYEGSVNWDEIKDPMIRQALEDQIRSFGQTPSQLVTEPHPPRNSALHVS 2390          
The following BLAST results are available for this feature:
BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
WDFY30.000e+031.97WD repeat and FYVE domain containing 3 [Source:HGN... [more]
WDFY30.000e+067.52WD repeat and FYVE domain containing 3 [Source:HGN... [more]
WDFY47.446e-8842.51WDFY family member 4 [Source:HGNC Symbol;Acc:HGNC:... [more]
LYST7.634e-12035.29lysosomal trafficking regulator [Source:HGNC Symbo... [more]
LRBA3.994e-10938.34LPS responsive beige-like anchor protein [Source:H... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wdfy-38.364e-3851.69WD40 and FYVE domain protein [Source:UniProtKB/Tr... [more]
wdfy-38.224e-3851.69WD40 and FYVE domain protein [Source:UniProtKB/Tr... [more]
wdfy-38.294e-3851.69WD40 and FYVE domain protein [Source:UniProtKB/Tr... [more]
wdfy-38.366e-3851.69WD40 and FYVE domain protein [Source:UniProtKB/Tr... [more]
sel-25.371e-9334.56Putative neurobeachin homolog [Source:UniProtKB/S... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bchs0.000e+053.09gene:FBgn0043362 transcript:FBtr0079144[more]
rg2.174e-10535.48gene:FBgn0266098 transcript:FBtr0344651[more]
rg2.482e-10535.48gene:FBgn0266098 transcript:FBtr0344649[more]
rg2.622e-10535.48gene:FBgn0266098 transcript:FBtr0344668[more]
rg2.695e-10535.48gene:FBgn0266098 transcript:FBtr0344648[more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wdfy30.000e+031.79WD repeat and FYVE domain containing 3 [Source:ZFI... [more]
wdfy40.000e+045.28WDFY family member 4 [Source:ZFIN;Acc:ZDB-GENE-090... [more]
lyst2.024e-11834.26lysosomal trafficking regulator [Source:ZFIN;Acc:Z... [more]
lyst2.321e-11834.26lysosomal trafficking regulator [Source:ZFIN;Acc:Z... [more]
nbeab7.710e-10533.93neurobeachin b [Source:ZFIN;Acc:ZDB-GENE-120329-2][more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
WDFY30.000e+037.94WD repeat and FYVE domain containing 3 [Source:NCB... [more]
WDFY30.000e+037.95WD repeat and FYVE domain containing 3 [Source:NCB... [more]
WDFY30.000e+037.74WD repeat and FYVE domain containing 3 [Source:NCB... [more]
ENSXETT00000044622.12.478e-11839.73pep primary_assembly:Xenopus_tropicalis_v9.1:7:371... [more]
LYST5.338e-11634.63lysosomal trafficking regulator [Source:NCBI gene;... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Wdfy30.000e+031.83WD repeat and FYVE domain containing 3 [Source:MGI... [more]
Wdfy30.000e+031.72WD repeat and FYVE domain containing 3 [Source:MGI... [more]
Wdfy30.000e+031.53WD repeat and FYVE domain containing 3 [Source:MGI... [more]
Wdfy43.061e-8742.58WD repeat and FYVE domain containing 4 [Source:MGI... [more]
Wdfy45.451e-7942.58WD repeat and FYVE domain containing 4 [Source:MGI... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IZQ1|WDFY3_HUMAN0.000e+031.97WD repeat and FYVE domain-containing protein 3 OS=... [more]
sp|Q6VNB8|WDFY3_MOUSE0.000e+031.83WD repeat and FYVE domain-containing protein 3 OS=... [more]
sp|E9Q2M9|WDFY4_MOUSE2.141e-8642.58WD repeat- and FYVE domain-containing protein 4 OS... [more]
sp|Q6ZS81|WDFY4_HUMAN3.576e-8742.51WD repeat- and FYVE domain-containing protein 4 OS... [more]
sp|Q55DM1|LVSA_DICDI1.066e-16139.74BEACH domain-containing protein lvsA OS=Dictyostel... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5G3JJ760.000e+037.94WD repeat and FYVE domain containing 3 OS=Xenopus ... [more]
A0A5G3HUJ10.000e+037.95WD repeat and FYVE domain containing 3 OS=Xenopus ... [more]
A0A5G3JJY30.000e+037.74WD repeat and FYVE domain containing 3 OS=Xenopus ... [more]
A0A5F8H7K00.000e+037.31WD repeat and FYVE domain containing 3 OS=Monodelp... [more]
M7BQI50.000e+037.37WD repeat and FYVE domain-containing protein 3 OS=... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wdfy34.067e-13359.56WD repeat and FYVE domain containing 3 [Source:NCB... [more]
lyst2.400e-11533.46lysosomal trafficking regulator [Source:ZFIN;Acc:Z... [more]
nbeal14.961e-10537.77neurobeachin-like 1 [Source:ZFIN;Acc:ZDB-GENE-1305... [more]
nbeal26.733e-10136.89neurobeachin-like 2 [Source:NCBI gene;Acc:10033083... [more]
lrba1.758e-10032.32LPS-responsive vesicle trafficking, beach and anch... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000000320.10.000e+060.36pep scaffold:Pmarinus_7.0:GL481331:460:21348:1 gen... [more]
ENSPMAT00000000322.19.166e-18062.73pep scaffold:Pmarinus_7.0:GL481331:12961:21303:1 g... [more]
ENSPMAT00000008664.11.975e-14828.51pep scaffold:Pmarinus_7.0:GL477107:533344:566732:-... [more]
ENSPMAT00000007035.11.187e-11034.05pep scaffold:Pmarinus_7.0:GL477366:176480:246408:1... [more]
ENSPMAT00000008649.11.577e-10731.19pep scaffold:Pmarinus_7.0:GL477107:529775:566732:-... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
BPH14.421e-10942.59Protein homologous to Chediak-Higashi syndrome and... [more]
VPS276.100e-1141.79Endosomal protein that forms a complex with Hse1p;... [more]
TAF59.275e-1023.53Subunit (90 kDa) of TFIID and SAGA complexes; invo... [more]
PIB11.460e-735.21RING-type ubiquitin ligase of the endosomal and va... [more]
FAB13.655e-733.871-phosphatidylinositol-3-phosphate 5-kinase; vacuo... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO339516.457e-11535.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459981.448e-8645.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO303797.540e-8536.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO467427.787e-7032.92Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO295461.460e-3146.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wdfy30.000e+030.87WD repeat and FYVE domain containing 3 [Source:NCB... [more]
lyst8.125e-11632.79lysosomal trafficking regulator [Source:NCBI gene;... [more]
lrba1.935e-10135.60LPS responsive beige-like anchor protein [Source:N... [more]
nbeal26.874e-9747.38neurobeachin like 2 [Source:NCBI gene;Acc:10116327... [more]
nbeab1.629e-9133.42neurobeachin [Source:NCBI gene;Acc:101155372][more]
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BLAST of WD repeat and FYVE domain-containing protein 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000039846.10.000e+099.47SMESG000039846.1[more]
SMESG000039846.10.000e+099.15SMESG000039846.1[more]
SMESG000039846.10.000e+099.04SMESG000039846.1[more]
SMESG000017089.11.198e-9746.03SMESG000017089.1[more]
SMESG000017089.11.307e-9746.03SMESG000017089.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014717 ID=SMED30014717|Name=WD repeat and FYVE domain-containing protein 3|organism=Schmidtea mediterranea sexual|type=transcript|length=11694bp
ATAAATGAAACAATTATTGTAAGAAAAAAGCAATTTAGAAATGAATTTTG
TACGAAGAATAGTCAATTCAAAAGTTGAAACAAATAGTAATAAACCAGGA
GTTTATGAAGATACAGATAGTTCACTAAATCAATTAAAAATACTATTTGC
GGATTATAAAACAAAAATTTCGAATTCTGAAATATCTGATCACGACCAAT
TATTGTATGATATTATACCTCTATTTCATAAAATATTTTGTCCTACTCCT
GGTATCGAATTATGCGAAAGATTTCAAGATGTTTTTACTTTTTGTTCTCA
TGTCTCTTCGTTAATGGTTAGAGAAATTAAGAAGCGAGCAACAAACCAAA
AAACAGAAGAAGCAAGCCTTGCTATTGTCCAATATTTACAACCAAATCTT
ACTCAAAATTCTAAAAACGAAGAAAATAAAGGGTGGGTGCTGTTAAATGT
TCTCATTATTCTCAGTCGTGGTCCTGCACCTTTAATTGAATGCATGATAA
CAGCTAGTCTACCTTCAACCTTTGTCAAATGTCTTTATATTTTTTTCGAC
TTACCAAATCCAGAAATAAATTGCAACCAGCAACAGCAACACGATTCCAT
GTTCACGTTAACGAGTGCCGGCAATAAATGCTGTAAATACGATCCGTTTA
CCGTTCATAGACGGAATATTTTATTAGACAATTTTAAACAAGTTTTACAA
CGGATTTGCTTTTATCCTGCAACAACAGAAGAATTGGTAAGAAAAGAAGA
TTTGAGATTGCTTTTTGGAGCAGTTGCAAGTTGGTGTCCATCTCACAATT
CCGGTTGGAGGAAAGCGGCCGCAGATGTTTTACAGACAATAGCTCACAAT
GGACTTTCTCAGTCAACTATTCAACATATATATCACAAAAAACTGATCTC
TCAATGTTTGAAAAATGTTACAAAAGGTGGTTTAAAGTCAATAGAAATAG
TTGATATATTTGTTACATTATTCCATTTGCTCCGTGAATCAAGTGATGTC
AATCAGATGTTACTCGATGATTTCAGAAACAGTCAAGGCTATGCCATTAT
TGAAGAATTCCTTATAAAATTGGAAAAAGAAATTTCCAATGAAACAGAAC
AAGATTCCATTCGAAGCCTAATAATTCTCATTGCTAAATTGACCACATGT
GGTTATGTTGAATTACGGCCGAAGCCAAATTTATCAGTAGATATTATTTA
TCCAATAGAGGGATTTGAATTGCCTATGCCAATGAATAAAAATGAAAGTA
TTCGAAACTATTATGCTTTTAATGTATTGCAATCAGTTTTCCTACACGCC
GAAACAGATTTTTTATGTCTACGGATTCTTGAAGCCATCAAAACCATATA
TCAACAGGATCCTGCCAATTATTTTATATTAGAACCTCAAAATACATTCC
AAGTCTTTTCAGAAAAATTACACAAAAAATCTTTGTCCGTTCAGGAAGAA
CTAGTTAATTTAATTGACTGCATTGTCGTAACGTTGAATTATGTGCCTGT
CAAAGAAATTAGTAGTTTATCTGTTATTATGAAAACATGCAATGTTGCTG
TTACGACCAGTTTATTAGTGAAGGCATTTATTCGATTGATTGAACACAAT
AAAATTTTCAAAGAAGTATTAAAGGACATGGGGATTTTGGAAATCTCTGT
CAATCAGTTACACAGTTATGCTTATAATTTGAAAAAAGAGCAAGATGCAG
GAATTTCAGACTCGGTAAATAATGAGCAGGATGAACTCGGATTATTATTA
ATCGACTTCTTGACTCTGTTGATAAGCAATTGTTCAAAAAACATTGAACT
CTTTAGAAAGATTGGAGGCAGTGGTTGCGTTTTAAGTCTTGTAAATTTTG
TTAAAAGCCAAACGAGAGCTTTGGAATTTATTAAAGTCCTTACTTTGAGC
TCTGGATCAGAAGAAGATATGAGCAATTTTCTTGGATTAATTAGATCAAT
TAACTCACAAAACTTAAATTTGAAAATAAAAGTACTTGAGTCTCTATTTA
TTGTTCTCAAAGAGTCTCATCGATGCCGAATTGTTTTTAGGAAAGTGCAC
AGCTTTGTTGTTTTTATTCAAGAACTCGTTCATTTAGAAGGCTGTTTTTC
ATTAATTGCTAAACCTCCATGGGATTTAATAATAAAACAAGAATTACTCG
AATATGTAAAATGTATTTTGTCAATTTTAACTATGGCTTTAAAGAAAGAA
CCCAGTAATGTCAGATACTTCCTGCTCAATGTAAGCTATGCTTCTCTTAC
AGAAGCAATACGGAATTTAGGTTGCTTCGGAAGTGATGTAGATCTAATAT
GCCATGAAAATTCTGAAGGTGTAAATAGTCAAAATTGGTCATCAAATCAA
GTATTTTATATGGAGAATCTAAGTGCCGATTATTCTGATGAAAACTCCGT
TTCGTTAAAAGACAATTTTGATGCGATTTTCCAAAATGGTAATTATCAAG
ATCTCCTTGACAAATGTTCTGAAACTACTCAACAAACAATCATCGCATGC
TGCATTTTGAAATTCATGTATGACAATGCCATTGAACAATTTGATAACCG
GTTGCTATTAAAGAAGAGTAAATTTTTATTTCGTTCTGATTCCAAACACT
ATTTGAAAACAATAGTTTCTGATTCCTCATTTATTCCGAATCCTATGAAA
TTGCCCGTTCCGCCAAGTTCCATAAACAATTGCCATTCGATCATTGTTCA
TCCTGAAGCCGTTATTAGTCTAATTCACCTCATTCCAGCTATTCGTTGCG
ACCAAAATCAATTTACCCATCAAATAGAATTGCAGATTTACATTTTGGAA
AGATTAAATTACTTATTTTCCATTGACCGAAATCTACAAATCATGTGTGA
ATCAGTTTCTATGCCATTAGAATTACTAAATCACTTCCAATTCGCAATGA
TAAATGAAAACCATCCTCTACACTCGCTTTCTTTGGCACTCTTTGAACGA
CTGGCTACTCAAAAAGTTACTCCGAAAAACGTTAGGGATTTCCTTCGCCT
TGCTGATCCCTTGTGTTGTCAACCAATTACTATTAATAAAGATGACATTA
ATACTATGGATTTAACTTCAAATTGTCGATATCAGCCTCATAACTGTGCA
GAATTTAAATTAGACAAAAATGGTAGTGGTCAGGATTTTTGCACATATAT
ATCTCAAATGCAGCGTCCAAATGGCGGTCCAATATCTCTAACAAGGGTTA
AAAGCCTTATCGGTATTACCACACAGCAAAATCAATCAGATCGAGTTTGT
GTTCCTATTATTAATGATTCTACCGGAGAAACTGATTATTCTGAAATGAG
ATTTGCTCAAATTCCTAGTTTTGTTGAAATGAATATGTGTTATGAAGGCT
TTGGTTGTTTGTTTTTACCATCTATTGCGCCTCAAAGTGTTTCATCTGGA
ATTTCCAGCGTCGGGCTAGTGTCACCAATCGAAAATAATATTATTGGAGG
CATTGGAATCGGCGAACGTGTGTTTCCACCGACTGGAGGTTTTTCATTTT
CCACTTGGATTTGTGTTCAAAAATTTAGTTCTATCGCAACTACGCACCCA
ATACGCCTATTAAGTCTTGCCAGAAGCCTCCAAGGAAGCAATGAATTTAT
ATCTTGTCTTAATATATCGATAATTAACAGTCCTAATCATGTCATATTGG
TTTCAACCAAAGAAGAAGTATTTGGAAACAGAGAACAAGAAAATTATTCC
GAATCTGCATCATCAGAATTTGTTGCAGAATTTCCTTGCGAAATGCTCTT
ACAAGAACATTGTTGGATTCATTTGGTATTAACATTTCACAGGCCGGGGA
TGATTAAGCACTCCTCGTGCAGTTGCTTTCTCAATGGTCAGTTAATTGAT
ACAAAAAAGTTGAATTATATATCACCTAATGTTTCATCGAGTTTTGGTAG
CATGGGCACGCTCATTACTTCTGTGTACGCATACATTGGCACGACTCCGA
ATAATCACAAAATAAGCAATCTATGTTGGCGTCAAGGCCCAGTTCATTTT
ATCGAAGAACCACTCACTGCATCAGTAGTATCAAACATTACAAGATTAGG
CCCGAATTATATTGGGAACTTTCAGAATCCAATTCTGGATTACGAAAACC
CTATTGGATCTTTGGTGGCAGAAGAAAAAGTTGTCTTCAGTTTATATGCC
AATAACATCAGTATTTTCACCCTGCCTCGAATTAACAAGATCTATAACGA
ACTCGATGGCACAGTTATTGCGAGACAACTTCATTTACACCCAAAAGAAA
AGTCGAGTCCGATCAGGATAATTCATAACGCTGCCGGTCATTTATCGGGA
GCAGGCCGTTCGCTTGGCGCTATTCTTATAGGCTATGAAGGAATTCGAAA
CTTCAGCCCAGCACCAATGACAAAAATAATAGATTGTGTAGGTGGATCCA
AAGTTCTTTTGGGTATTTTAGCCATGGCAAATGACGCGGAAAATTTGTAC
GCTGTTGTCAAATTGATGTGCTCTTTTCTTATCGATAATAGATCCCTACT
AAAAGAACTTGAAAGCCATTTAGGATATAAACTTATTAGCTTCTTACTCA
AAAAGAAACGTCATTTATTAAGTTCTAGAATATTTAGTTTGTTAGTGGGT
CTAACTGGATCTGCTGATCAGGAATTTCAGGATATAAAAATTGAGAAAGG
AAAACAGCAAATAATCCATATTTCGTCTCTGAATAAATCATTCAACAGGA
ATCTTTTCGGAGAGGTTATTTGTGACTTGAATTTGTGGTTGCATTGTATT
AACATCGACAACAATAATAATCAATTATTGGGTAATGTTCTTCGGCATAT
AAGTGAATTCTTCCAAAAATGTGTCGATAGCAAATATGTTAGTGATTCCT
CGGAAAGAGATATAAAAACTTGTAGAACAACTTCGATTCTCAAATATCTA
TTGGATCTTAATTTAATGGAGAGAATTATAGATCTGATGATGCAATTCAA
TATTAATCCGCTAAACACAATAATTAATGAGCCATTGTCAAAACTCATTG
AGCTTATAATATCATATTCCAATAAGCCAGATGATTTGAGAAGGTTCGGT
CAATTTATGGTTTGGACGCTTTCAGCTCTTGGAACATCAGAAACGAAAAT
TAATTTAAATGAAAATAATAAATCAGATCTCGAATCAGCCGAATTCAAAA
ATACGATTTATTTAATAGAGATTAGAAATATGTGCTTCAAGATTATTCTC
AAAATTCTAAACAATTCAATAAATAGTGAAACTAATGAACCGAAAATCGC
TGAAGAATTATTGAAATATTTGGGATTTGATTGGATTTTGTTATTTATGC
AACCCGATGTCCATCCTAGCACCGTTGTATTAGCAATGCGCTGTTTAGTG
ACATTATTATCAGTTCCGCAATATATCTTAAAATTCAGAGATGGGATTTT
ATGTTCGGGTTGGTTGACTGGTACCGATTTGGTCCTGCAGAAAAGGCACG
GATTGCTTTTAATGGATAATGCCCGAGATCAACCAGCAGCTCTAAGAGAA
ATTAATTTGGATTCTTGCCATCTGCCCGGATTCGTTTACCTTCAGTCTCT
TTTACCTCATCATTGTCGTATACCCGATATTTATTTCATGCTGATCGCTC
TCCTGTTGGGAAACAAAATTAAAAACATTCCAGATAATTTGAAGGAAACT
AATCCTAAAACTTGGCTAGAAAATATGGAAGCCAATTTTGAAATATCCTG
TGAAGCAAATCAATCTCAGTTTGAATTCGAATCGGTGTGTAATTTTCTTT
TTGGCAATTCTACTGAACAAAGTCAAGCCTCTAATAAACAAGCATCTGGA
TCTGGATGGACTGCTGGACCAATTGGCGTTCTTCTAAATAGGATTGATTA
TCAGAACAATGCAAATAAAAAGTCTAATGTTGTAAAAAAATCTGTTGAAA
TGTGCAGTGAAGCAGCTACTATTTTATTAACCATGATGCGTGTAATGCTA
AATCAGAATTGTAATGAATGTGACAATGAAAATCATACTTGGATCAGAGA
TTACCCAATAACTTTATTGAGATTCTTCGTCTATCTTTATCATTCAAATG
CTGAATTTCAATCAGTAGCTATGCAGAGTGATTTTCTCATCGGTCTGACT
GGAGCTATGTATCCATCTAGTGATCCTGGAATGAAATCATCTCCCAAGAA
AATTAATCTGTTTTCTCCAGAGTCAATAATTTTTACAGAAAATGAAAAGT
GTGGCAATGTGATAAATAACATCCGCAATACAGAAATGATTACATTAGAA
TCTTTAAATTCTTTACCAGCGAGGAAATTAATCATGGATTTTTTCAAAAT
GATTATAGTTGACTATTTTTCTCTACCGAAAAATTCATATCAGCATGTTA
TTGATATAATACTAGAATGTGACATTGAAAACACAACACAAGAACATATG
AAACAATTCCAAACCGTTTTTATGAATAGTTTGACGGAACATTTTATGGC
TGTGGATATTTTGAGTGGACAAAATCTACCTCTTCCTCCTGGAGGAAGTT
ACGCTAATATTCCAAATAATATATATTACTTTTTCAGTCGAGTTGTTGAT
AAAGTCTGGCAAGAAAACTATGTAGATGATCCCGATGTGATCATTTCATA
CTTATGCCGTCTGATCTCTCAGGGAAGAAAAAGACAAATCACTCAAGAAT
CATTGTATCGGTCATTCAACCGATTAATTCTTTTTCGATTATCTAGACGA
ATAGCGGAACTTAAAAATAAAAAATTAATTCTTAAGACACTGCAAAAGTT
GTTGAAAAAAAGTGAAACAACTGATTATGGCAGTGGGATTTTCAACCCAG
CTAATTCTGACGGTGAATTTGTCGTCTGTTTAGTCCATTTACTGATCCAG
TTGATTAATGGCATAAACATCGTTGGCTACTCCACTTGGTATAATCCAGA
TTCCATATCCACTGACAATATCAAGGACAATGAAAATCAAATGAAATACC
TGAAATTAAATGAGCAAATACGGTCAAATGCTGAATCCTTATGGCAGGAA
ATTTCCACTAATAAAAAGCAGTTGCTGGAAGAAGCTTTTAAAATTCAATT
ATCCTCAAACCTTCTGTCGATTTCTCCAAATATTGAACAGATTTGTTTAA
AAACCTGGAATAGTTACATTGAGAGTGAAAATATTGGTACTGCATCTAGT
CATTGGGGACGAATCTCACTAAATATTCCATTATCTGGTGGAAGAGATTC
CTCGATTAATACAGGCTCAAATGTATCCCAAAGTTTACAACATCAAATCT
CTATCAAACTAAATCGAATGTCAAGAAATAGTGTCCTTGGCAGACTGAGT
AGTTCAACTTCTATAACCACAGCTTCTGGATCGGGAAGTTTTTCCTCTAG
TATTGGTGCATCACGACTACTAAATCATGTTTCCCTAGAAGAAGCTAGAC
TTTGGATCCCACCTCATATATCTGTCGTTAAGGAGTTAATGGACTATCAC
AAAAACGTTTTCCTGAAAAAAGAATCATTTATGATGCATTACCTCGAATC
TAAATGGAAATCTGTTGAATCTGAATTGAATCGTGAAAGAGGCCTGTGGG
GACCAATGGTTGGTAGTTGTCTGGATAAATGGATGCTTGACTCTGCAGAA
GGACCTTGTCGAATGCGAAAGAAAATGATTCCGAATGAATACTTTTATCA
GCATTATCCATACAGACCGTATCATAGATCCCCATGTGATAACAATGAAA
ATCACTGTCAGGTATATCAGATTAAAAAGTTTAAAGTTGCCGCTAGTGCT
GATGGTGAACTTTACTATTGCTTTTCCATGTCAAAATCTATTTTAAAAAC
TGATGAATATCAACAATTGTCGCCGGCTTTGGATATGAATGATTCAAATA
ATCCTAAAACAGTGGAAGAAAATATTAATTGTTCAAATGAAGATCCGGAA
GAATCTCTTCGTAATACGGAATCTTTGCTGAGAGGTCGAAAAGTAAGTGT
CAGCATTTTAGATACTTCTATTCCAATGAAAGGTGACAATAAAATCGACG
ATGAGTGGCAGGATACTAAATTCAAACCAGAAGATATTATTGATCAGGAA
GATGAAGAAACGTTTAATAAGGACAATATGTTTTCAGACACTGTTGATGA
TTCCGATTTCCCTCTAGATACAGAAAAAACATCGAGAAGCGAGTCAAAAT
TAAAAAAATTAAATTCCGAACAATCTTTGGATTCATCTGCAATAATTCCG
AATCCATCAGCTCAATCACAAGAATCGGCGAAGAAACAATCTAGCATTTC
CACTCAATGGGATAATCAGGTTGCGATTGAACATATGATAGGATCAGATG
AGAAAATTCATTTTATGTTTCGATGTGCCAGAATTCAAGGTTTGGATGTC
CATGAAGGTCTGTTATTATTCGGACAAAGTTATTTCTATATTATCGATGG
ATTTACTTTGTTGAAAACAAGAGAAATAGTTGAAATAAACAATATTCCTA
TTGATGTACATGAACCCATTGTTCCTTCAACTCCAACTGTCAATACTTTC
AATCACCGAAGAAAAATGAGTGACAAATTCTCTTTTGGTGAAATCAGAGA
GGTCCATAAACGGCGATATTTGTTACAGCCGATTGCAGTTGAAGTATTTT
TGGGAGATGGGAGAAATTTTTTGCTAGCATTTCCAAAGAAAATGCAAAAT
AAAATTTATGCCAAATTTATTCAAGTTGCGTCCTCATTGACTTTAAATGC
TCAGCATAGCATTTCTGGGCAGAAGCAAAACTCAAAAATCGAAGCTGGAA
GCACTAGTATATTCAGTAACTTTATGGGCGAAAAATCTGTAACTCAGCGG
TGGGAGAAAGGAGAAATCAGTAATTTTCAATATTTGATGTACTTGAATAC
TTTGGCCGGCAGATCATATAATGATTTAATGCAATATCCTGTTTTCCCTT
GGATTTTAGCTGATTATGAAAGTGAAACCCTAGATTTGACTTCTCCTTCT
ACTTTCCGGCAATTAGACAAACCAATGGGAGCTCAGAGTGAAAATAGATT
ACATCAATTTGAAAAAAGGTATCGAGAATGGGATGATCCGAGTGGAGAGA
CCCCTCCGTATCATTATGGCACTCATTATTCATCAGCAATGATTGTCGCA
TTTTATCTCGTTCGGATGGAACCCTTTACACAACATTTTCTGAAATTACA
AGGTGGTCATTTTGATCTAGCCGATCGTATGTTCCATTCTATTAAAGATA
CATGGGAAAGCGCCAGTCAACATAACATGGCCGATATTAAAGAACTGATT
CCTGAATTTTTCTATCTTCCAAATTTCTTAAACAATACCAACAAATTTGA
TTTGGGAAATAAGCAAAACGGAGTTGTGCTCGGTGATATATTGTTGCCTC
CTTGGGCTAAAGGAGATTCGAGAGAATTTATTCGAGCTCACAGAGAAGCA
TTGGAATGTGATTACGTTTCTGCTCATTTAAATGAATGGATTGATTTGAT
ATTCGGGTATAAGCAGCTTGGTGATGCTGCAGTTGAAGCTGTGAATGTAT
TCCATCATTTATTCTACGAAGGTAATGTAGACATTTATTCAATCGATGAT
CCGTTGAAAAGATCTGCTGTTATTGGTTTCATCAACAATTTCGGTCAAAT
ACCCAAACAACTATTCAAAAAACCCCATCCAACAAAGCGGCTGCTTATAC
CAATATCAATTATTAATAAACAGATTGACCCAATGGCCCCGTTAGCCAGC
AGTGCACCGGCGGAACGGTTATTTTATCACAATTTGGATAATATGGAACC
TTCGTTGCAACCGGTGAAAGAACTGAAAAATGCTGTCGGTCAAATAATTC
AAGCTGATTTAAATGGGACTAATTCAAATGCGGTTGGTTCTGTACCGAGT
TCAGTTCTTGCTGTTGAACAAAACAAGTGTCTTATTCCTCCATTATACAC
TCGCTATGTGGCGTGGGGATTTTCTGATGGTAGCTTGAGGGTCGGCAATT
ACGACTCAGATAAATTAATCAAAGTTTATGAAATGCCAGATCCTTATGGG
GATATAATGTGTGTCCTTTGTCTGAATGAGCGCATTTTGATAACCGGTGG
CTTTAGTACGGTCGTTCGCGTTTGGAATATGTCGGTTAATGCCAGTAAAC
CAACAGCATCTGGTAGTGCTGGGTCGCGTTTGACAGGTGGTTTAGCACCA
GCATTGAGTTTGCAAGCAAATTTATATGGCCACATTGAAGCTGTTACATG
CTTAGCTGTTGCTGCATCTTATAATCTCCTCGTTTCCGGGAGTCGCGATC
GTACCTGCATAATGTGGGACCTGGGTAGGATGTGTTATTTGAGACAATTG
AGTGGACACGCAGCGCCAGTGGCAGCGATATGTATTAGTGAAGTGACTGG
GATGGTAGCTAGTTGTGCTGGAACGTATTTGCATTTGTGGAGTATTGATG
GTGAAGAACTTGCATCAGTTAATACTGCTACAGGTCGAAGCAAACAAATT
CTTACTGTTACAATGAGCACTATGATGGATTGGGATCCTGGAAATGTCGT
TATAACCGGCGGAACTGATGGTGTAGTACGAATGTGGAGTCTCGAATATG
TTCAAGTTCCGATTTCTACTTCATTTTGTTCAGCTGATTTCAGTGAACCC
CAGGCGGTAAGTTCACAGCCTGGTTTTGAATCCGTGTCTTCAGTTTGTGA
AAGTTCAAATTTGGAAGAAGATGAATATGATCAGGAAGAAATATGGCAGT
CCTCAAAATCCATTGAAAATAAATCACAAACTGCTACCTTGACTAGGTCA
AACATGGCAATTAGCATTGATAATAAAGATAAGTCTTCAGATGAGCTTGA
TGAAGAATATGTAGTTATTGGTTCAAATGAGATCAATTCCGATCTAGTCA
ATAAATCCGTATTGTCCGAAGATGGTATTAATATTGTTGAAAGGGCAAAT
AATTCGAAGGTGCAAAGCACATTATTGAAATCATTATCACAGCCTCAAAT
GCGCCCAAATATGAGAAAATTGAGGAAAGGATTTCATTGGCAAAGACAAT
TGATATTCCGGAGTAAACTAACAATGCATACTGCGTATGAAAGATCAGAT
AATGCTAATCCTTCTCCAATCAGTTCACTGGCAATTTCACGAGATCATCG
AAGTATTTATGTTGGTGATCAAAGGGGACGAGTATTTTTTTGGTCAGTAC
CACAAGAGCCGGGTCGATCAATGGCAGATCATTGGATTCGTGATGAGAAC
GCTGAAGTTTGTATCGGTTGCAAAATCAGGTTCTCTTTGACAGAAAGGAG
GCATCATTGTAGAAATTGCGGACTCGTTTTTTGCAATAAGTGCAGTAAAC
ATGAAACAGAAATCCATCGACTTCGTTTATTCAAACCGGTCAGAGTTTGT
GCAAAATGTTTCTATTCCATCACTAGTCAACAATCAAGCTAAATTTGCAA
AAGGAATCATCTGAGAATAAATGATTTAGGAATCGCATTTGACCTGGTTA
AATTCTGTGATTAGTCTCTCATCGGCATAATTGATTGAAAGATGATAATT
ATATTTATTTGTTTTAATTGGAGAAAAATTGATATTTATTGATTCGTTTT
AGATGGAATATTTCATTTGTTTCTGGTGTATTATAGTACTGATATAAATT
TTAGTGCGCGTTTTGTATACTCACGATATTGTTTACGGGCATATTCTTTG
TGATTATATTGTAGATAATATGATAATCCATCTTTGAAAAAAAA
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protein sequence of SMED30014717-orf-1

>SMED30014717-orf-1 ID=SMED30014717-orf-1|Name=SMED30014717-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=3784bp
MNFVRRIVNSKVETNSNKPGVYEDTDSSLNQLKILFADYKTKISNSEISD
HDQLLYDIIPLFHKIFCPTPGIELCERFQDVFTFCSHVSSLMVREIKKRA
TNQKTEEASLAIVQYLQPNLTQNSKNEENKGWVLLNVLIILSRGPAPLIE
CMITASLPSTFVKCLYIFFDLPNPEINCNQQQQHDSMFTLTSAGNKCCKY
DPFTVHRRNILLDNFKQVLQRICFYPATTEELVRKEDLRLLFGAVASWCP
SHNSGWRKAAADVLQTIAHNGLSQSTIQHIYHKKLISQCLKNVTKGGLKS
IEIVDIFVTLFHLLRESSDVNQMLLDDFRNSQGYAIIEEFLIKLEKEISN
ETEQDSIRSLIILIAKLTTCGYVELRPKPNLSVDIIYPIEGFELPMPMNK
NESIRNYYAFNVLQSVFLHAETDFLCLRILEAIKTIYQQDPANYFILEPQ
NTFQVFSEKLHKKSLSVQEELVNLIDCIVVTLNYVPVKEISSLSVIMKTC
NVAVTTSLLVKAFIRLIEHNKIFKEVLKDMGILEISVNQLHSYAYNLKKE
QDAGISDSVNNEQDELGLLLIDFLTLLISNCSKNIELFRKIGGSGCVLSL
VNFVKSQTRALEFIKVLTLSSGSEEDMSNFLGLIRSINSQNLNLKIKVLE
SLFIVLKESHRCRIVFRKVHSFVVFIQELVHLEGCFSLIAKPPWDLIIKQ
ELLEYVKCILSILTMALKKEPSNVRYFLLNVSYASLTEAIRNLGCFGSDV
DLICHENSEGVNSQNWSSNQVFYMENLSADYSDENSVSLKDNFDAIFQNG
NYQDLLDKCSETTQQTIIACCILKFMYDNAIEQFDNRLLLKKSKFLFRSD
SKHYLKTIVSDSSFIPNPMKLPVPPSSINNCHSIIVHPEAVISLIHLIPA
IRCDQNQFTHQIELQIYILERLNYLFSIDRNLQIMCESVSMPLELLNHFQ
FAMINENHPLHSLSLALFERLATQKVTPKNVRDFLRLADPLCCQPITINK
DDINTMDLTSNCRYQPHNCAEFKLDKNGSGQDFCTYISQMQRPNGGPISL
TRVKSLIGITTQQNQSDRVCVPIINDSTGETDYSEMRFAQIPSFVEMNMC
YEGFGCLFLPSIAPQSVSSGISSVGLVSPIENNIIGGIGIGERVFPPTGG
FSFSTWICVQKFSSIATTHPIRLLSLARSLQGSNEFISCLNISIINSPNH
VILVSTKEEVFGNREQENYSESASSEFVAEFPCEMLLQEHCWIHLVLTFH
RPGMIKHSSCSCFLNGQLIDTKKLNYISPNVSSSFGSMGTLITSVYAYIG
TTPNNHKISNLCWRQGPVHFIEEPLTASVVSNITRLGPNYIGNFQNPILD
YENPIGSLVAEEKVVFSLYANNISIFTLPRINKIYNELDGTVIARQLHLH
PKEKSSPIRIIHNAAGHLSGAGRSLGAILIGYEGIRNFSPAPMTKIIDCV
GGSKVLLGILAMANDAENLYAVVKLMCSFLIDNRSLLKELESHLGYKLIS
FLLKKKRHLLSSRIFSLLVGLTGSADQEFQDIKIEKGKQQIIHISSLNKS
FNRNLFGEVICDLNLWLHCINIDNNNNQLLGNVLRHISEFFQKCVDSKYV
SDSSERDIKTCRTTSILKYLLDLNLMERIIDLMMQFNINPLNTIINEPLS
KLIELIISYSNKPDDLRRFGQFMVWTLSALGTSETKINLNENNKSDLESA
EFKNTIYLIEIRNMCFKIILKILNNSINSETNEPKIAEELLKYLGFDWIL
LFMQPDVHPSTVVLAMRCLVTLLSVPQYILKFRDGILCSGWLTGTDLVLQ
KRHGLLLMDNARDQPAALREINLDSCHLPGFVYLQSLLPHHCRIPDIYFM
LIALLLGNKIKNIPDNLKETNPKTWLENMEANFEISCEANQSQFEFESVC
NFLFGNSTEQSQASNKQASGSGWTAGPIGVLLNRIDYQNNANKKSNVVKK
SVEMCSEAATILLTMMRVMLNQNCNECDNENHTWIRDYPITLLRFFVYLY
HSNAEFQSVAMQSDFLIGLTGAMYPSSDPGMKSSPKKINLFSPESIIFTE
NEKCGNVINNIRNTEMITLESLNSLPARKLIMDFFKMIIVDYFSLPKNSY
QHVIDIILECDIENTTQEHMKQFQTVFMNSLTEHFMAVDILSGQNLPLPP
GGSYANIPNNIYYFFSRVVDKVWQENYVDDPDVIISYLCRLISQGRKRQI
TQESLYRSFNRLILFRLSRRIAELKNKKLILKTLQKLLKKSETTDYGSGI
FNPANSDGEFVVCLVHLLIQLINGINIVGYSTWYNPDSISTDNIKDNENQ
MKYLKLNEQIRSNAESLWQEISTNKKQLLEEAFKIQLSSNLLSISPNIEQ
ICLKTWNSYIESENIGTASSHWGRISLNIPLSGGRDSSINTGSNVSQSLQ
HQISIKLNRMSRNSVLGRLSSSTSITTASGSGSFSSSIGASRLLNHVSLE
EARLWIPPHISVVKELMDYHKNVFLKKESFMMHYLESKWKSVESELNRER
GLWGPMVGSCLDKWMLDSAEGPCRMRKKMIPNEYFYQHYPYRPYHRSPCD
NNENHCQVYQIKKFKVAASADGELYYCFSMSKSILKTDEYQQLSPALDMN
DSNNPKTVEENINCSNEDPEESLRNTESLLRGRKVSVSILDTSIPMKGDN
KIDDEWQDTKFKPEDIIDQEDEETFNKDNMFSDTVDDSDFPLDTEKTSRS
ESKLKKLNSEQSLDSSAIIPNPSAQSQESAKKQSSISTQWDNQVAIEHMI
GSDEKIHFMFRCARIQGLDVHEGLLLFGQSYFYIIDGFTLLKTREIVEIN
NIPIDVHEPIVPSTPTVNTFNHRRKMSDKFSFGEIREVHKRRYLLQPIAV
EVFLGDGRNFLLAFPKKMQNKIYAKFIQVASSLTLNAQHSISGQKQNSKI
EAGSTSIFSNFMGEKSVTQRWEKGEISNFQYLMYLNTLAGRSYNDLMQYP
VFPWILADYESETLDLTSPSTFRQLDKPMGAQSENRLHQFEKRYREWDDP
SGETPPYHYGTHYSSAMIVAFYLVRMEPFTQHFLKLQGGHFDLADRMFHS
IKDTWESASQHNMADIKELIPEFFYLPNFLNNTNKFDLGNKQNGVVLGDI
LLPPWAKGDSREFIRAHREALECDYVSAHLNEWIDLIFGYKQLGDAAVEA
VNVFHHLFYEGNVDIYSIDDPLKRSAVIGFINNFGQIPKQLFKKPHPTKR
LLIPISIINKQIDPMAPLASSAPAERLFYHNLDNMEPSLQPVKELKNAVG
QIIQADLNGTNSNAVGSVPSSVLAVEQNKCLIPPLYTRYVAWGFSDGSLR
VGNYDSDKLIKVYEMPDPYGDIMCVLCLNERILITGGFSTVVRVWNMSVN
ASKPTASGSAGSRLTGGLAPALSLQANLYGHIEAVTCLAVAASYNLLVSG
SRDRTCIMWDLGRMCYLRQLSGHAAPVAAICISEVTGMVASCAGTYLHLW
SIDGEELASVNTATGRSKQILTVTMSTMMDWDPGNVVITGGTDGVVRMWS
LEYVQVPISTSFCSADFSEPQAVSSQPGFESVSSVCESSNLEEDEYDQEE
IWQSSKSIENKSQTATLTRSNMAISIDNKDKSSDELDEEYVVIGSNEINS
DLVNKSVLSEDGINIVERANNSKVQSTLLKSLSQPQMRPNMRKLRKGFHW
QRQLIFRSKLTMHTAYERSDNANPSPISSLAISRDHRSIYVGDQRGRVFF
WSVPQEPGRSMADHWIRDENAEVCIGCKIRFSLTERRHHCRNCGLVFCNK
CSKHETEIHRLRLFKPVRVCAKCFYSITSQQSS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0000103central nervous system
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036372BEACH_dom_sf
IPR036322WD40_repeat_dom_sf
IPR001680WD40_repeat
IPR000306Znf_FYVE
IPR000409BEACH_dom
IPR023362PH-BEACH_dom
IPR013083Znf_RING/FYVE/PHD
IPR015943WD40/YVTN_repeat-like_dom_sf
IPR019775WD40_repeat_CS
IPR017986WD40_repeat_dom
IPR017455Znf_FYVE-rel
IPR011011Znf_FYVE_PHD
IPR011993PH-like_dom_sf
IPR011528NERD
IPR027310Profilin_CS
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0046872metal ion binding
GO:0003779actin binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001680WD40 repeatSMARTSM00320WD40_4coord: 3413..3451
e-value: 2.2
score: 14.8
coord: 3464..3500
e-value: 0.3
score: 20.1
coord: 3663..3702
e-value: 5.2
score: 12.5
coord: 3306..3346
e-value: 1.1
score: 16.8
coord: 3371..3410
e-value: 2.2E-6
score: 37.2
IPR001680WD40 repeatPFAMPF00400WD40coord: 3375..3410
e-value: 3.8E-5
score: 24.4
IPR001680WD40 repeatPROSITEPS50082WD_REPEATS_2coord: 3484..3502
score: 8.771
IPR001680WD40 repeatPROSITEPS50082WD_REPEATS_2coord: 3378..3411
score: 12.246
IPR000409BEACH domainSMARTSM01026Beach_2coord: 2918..3199
e-value: 1.4E-207
score: 705.6
IPR000409BEACH domainPFAMPF02138Beachcoord: 2919..3198
e-value: 7.5E-123
score: 409.3
IPR000409BEACH domainPROSITEPS50197BEACHcoord: 2906..3199
score: 127.03
IPR000409BEACH domainCDDcd06071Beachcoord: 2918..3199
e-value: 2.0675E-148
score: 460.557
IPR000306FYVE zinc fingerSMARTSM00064fyve_4coord: 3710..3779
e-value: 6.9E-22
score: 88.7
IPR000306FYVE zinc fingerPFAMPF01363FYVEcoord: 3714..3777
e-value: 9.9E-17
score: 60.8
IPR036372BEACH domain superfamilyGENE3DG3DSA:1.10.1540.10coord: 2909..3199
e-value: 2.5E-136
score: 455.8
IPR036372BEACH domain superfamilySUPERFAMILYSSF81837BEACH domaincoord: 2909..3199
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 3703..3783
e-value: 2.2E-22
score: 80.5
IPR023362PH-BEACH domainPFAMPF14844PH_BEACHcoord: 2821..2875
e-value: 2.6E-11
score: 43.5
IPR023362PH-BEACH domainPROSITEPS51783PH_BEACHcoord: 2751..2877
score: 30.693
IPR023362PH-BEACH domainCDDcd01201PH_BEACHcoord: 2754..2880
e-value: 3.20847E-36
score: 132.359
NoneNo IPR availableGENE3DG3DSA:2.30.29.40coord: 2804..2875
e-value: 4.8E-9
score: 38.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 2709..2738
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 2655..2708
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 2655..2738
NoneNo IPR availablePANTHERPTHR46108FAMILY NOT NAMEDcoord: 1..1907
NoneNo IPR availablePANTHERPTHR46108:SF1WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 3coord: 1945..2546
NoneNo IPR availablePANTHERPTHR46108FAMILY NOT NAMEDcoord: 2725..3738
coord: 1945..2546
NoneNo IPR availablePANTHERPTHR46108:SF1WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 3coord: 2725..3738
coord: 1..1907
NoneNo IPR availableCDDcd15719FYVE_WDFY3coord: 3713..3777
e-value: 2.3816E-35
score: 127.887
NoneNo IPR availableSUPERFAMILYSSF50729PH domain-likecoord: 2754..2879
IPR015943WD40/YVTN repeat-like-containing domain superfamilyGENE3DG3DSA:2.130.10.10coord: 3265..3584
e-value: 6.2E-29
score: 102.9
IPR019775WD40 repeat, conserved sitePROSITEPS00678WD_REPEATS_1coord: 3397..3411
IPR017455Zinc finger, FYVE-relatedPROSITEPS50178ZF_FYVEcoord: 3718..3778
score: 12.636
IPR017986WD40-repeat-containing domainPROSITEPS50294WD_REPEATS_REGIONcoord: 3378..3509
score: 19.196
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILYSSF57903FYVE/PHD zinc fingercoord: 3713..3781
IPR036322WD40-repeat-containing domain superfamilySUPERFAMILYSSF50978WD40 repeat-likecoord: 3286..3705