Transcription factor 7-like 1

Overview
NameTranscription factor 7-like 1
Smed IDSMED30014712
Length (bp)2726
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transcription factor 7-like 1 (SMED30014712) t-SNE clustered cells

Violin plots show distribution of expression levels for Transcription factor 7-like 1 (SMED30014712) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transcription factor 7-like 1 (SMED30014712) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transcription factor 7-like 1 (SMED30014712) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014712

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30014712h1SMcG0018146 dd_Smed_v4_8152_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30014712h1SMcG0018146 dd_Smed_v4_8152_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30014712h1SMcG0018146 dd_Smed_v6_8152_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30014712h1SMcG0018146 OX_Smed_1.0.04122ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30014712h1SMcG0018146 KY196228smed_ncbi_20240424PMID:28976975
Su et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
cephalic gangliaSMED30014712h1SMcG0018146 KY196228smed_ncbi_20240424PMID:28976975
Su et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30014712h1SMcG0018146 KY196228smed_ncbi_20240424PMID:28976975
Su et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30014712h1SMcG0018146 KY196228.1smed_ncbi_20240424PMID:28976975
Su et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
cephalic gangliaSMED30014712h1SMcG0018146 KY196228.1smed_ncbi_20240424PMID:28976975
Su et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30014712h1SMcG0018146 KY196228.1smed_ncbi_20240424PMID:28976975
Su et al., 2017		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Human
Match: TCF7 (transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639])

HSP 1 Score: 155.221 bits (391), Expect = 1.397e-41
Identity = 79/146 (54.11%), Postives = 98/146 (67.12%), Query Frame = 3 
Query: 1140 KDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            K++ KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY      KKKRR                    S+  + ++T     D  + KKCRAR+G+ Q + W
Sbjct:  147 KEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKRR--------------------SREKHQEST----TDPGSPKKCRARFGLNQQTDW 263
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Human
Match: TCF7 (transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639])

HSP 1 Score: 157.532 bits (397), Expect = 2.060e-40
Identity = 80/152 (52.63%), Postives = 100/152 (65.79%), Query Frame = 3 
Query: 1122 CKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
             +S   K++ KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY      KKKRR                    S+  + ++T     D  + KKCRAR+G+ Q + W
Sbjct:  256 AESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKRR--------------------SREKHQEST----TDPGSPKKCRARFGLNQQTDW 378
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Human
Match: TCF7 (transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639])

HSP 1 Score: 147.517 bits (371), Expect = 9.152e-40
Identity = 68/98 (69.39%), Postives = 80/98 (81.63%), Query Frame = 3 
Query: 1122 CKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR 1415
             +S   K++ KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY      KKKRR
Sbjct:   45 AESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKRR 137
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Human
Match: TCF7 (transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639])

HSP 1 Score: 144.821 bits (364), Expect = 1.448e-39
Identity = 68/98 (69.39%), Postives = 80/98 (81.63%), Query Frame = 3 
Query: 1122 CKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR 1415
             +S   K++ KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY      KKKRR
Sbjct:   34 AESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKRR 126
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Human
Match: TCF7 (transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639])

HSP 1 Score: 146.362 bits (368), Expect = 1.564e-38
Identity = 68/98 (69.39%), Postives = 80/98 (81.63%), Query Frame = 3 
Query: 1122 CKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR 1415
             +S   K++ KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY      KKKRR
Sbjct:  141 AESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKRR 233
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Celegans
Match: pop-1 (pep chromosome:WBcel235:I:2823254:2830311:-1 gene:WBGene00004077.1 transcript:W10C8.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:pop-1)

HSP 1 Score: 110.923 bits (276), Expect = 1.595e-25
Identity = 60/142 (42.25%), Postives = 84/142 (59.15%), Query Frame = 3 
Query: 1158 HIKKPLNAFMLFMKEMRQTVQEECT--LKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            H+KKPLNAFM FMKE R+ + EE     K+SA +N+ LGK+WH LS+EEQ+KY+E+AKK+K+ H + +P+WSAR+NYA++ K  KKR                                  ++NN+ KKCRAR+G+     W
Sbjct:  191 HVKKPLNAFMWFMKENRKALLEEIGNNEKQSAELNKELGKRWHDLSKEEQAKYFEMAKKDKETHKERYPEWSARENYAVNKKKTKKR----------------------------RDKSIPSENNDQKKCRARFGVNNTEMW 304
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Celegans
Match: gei-3 (GEX Interacting protein [Source:UniProtKB/TrEMBL;Acc:Q0G834])

HSP 1 Score: 68.9366 bits (167), Expect = 1.712e-11
Identity = 24/71 (33.80%), Postives = 52/71 (73.24%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDW 1364
            +PH+++P+NAFM+F K  R  V ++   K++  +++ILG+ W++L+ +++++Y+++A + K+ H +  PDW
Sbjct:  840 EPHVRRPMNAFMIFSKRHRPLVHQQYPNKDNRTVSKILGEWWYSLAADQKAEYHKLATQVKEAHFKAHPDW 910
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Celegans
Match: gei-3 (GEX Interacting protein [Source:UniProtKB/TrEMBL;Acc:Q0G834])

HSP 1 Score: 67.781 bits (164), Expect = 2.215e-11
Identity = 24/71 (33.80%), Postives = 52/71 (73.24%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDW 1364
            +PH+++P+NAFM+F K  R  V ++   K++  +++ILG+ W++L+ +++++Y+++A + K+ H +  PDW
Sbjct:   75 EPHVRRPMNAFMIFSKRHRPLVHQQYPNKDNRTVSKILGEWWYSLAADQKAEYHKLATQVKEAHFKAHPDW 145
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Celegans
Match: egl-13 (Transcription factor egl-13 [Source:UniProtKB/Swiss-Prot;Acc:Q23045])

HSP 1 Score: 58.151 bits (139), Expect = 1.672e-8
Identity = 26/82 (31.71%), Postives = 49/82 (59.76%), Query Frame = 3 
Query: 1146 SPKP------HIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSAR 1373
            +P+P      HIK+P+NAFM++ ++ R+ + +      ++ I++ILG +W  +S  E+  YYE   +  +LH++  PD+  R
Sbjct:  270 TPRPQAKSPNHIKRPMNAFMVWARDERRKILKAYPDMHNSNISKILGSRWKGMSNSEKQPYYEEQSRLSKLHMEQHPDYRYR 351
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Celegans
Match: egl-13 (Transcription factor egl-13 [Source:UniProtKB/Swiss-Prot;Acc:Q23045])

HSP 1 Score: 57.3806 bits (137), Expect = 1.789e-8
Identity = 24/72 (33.33%), Postives = 45/72 (62.50%), Query Frame = 3 
Query: 1158 HIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSAR 1373
            HIK+P+NAFM++ ++ R+ + +      ++ I++ILG +W  +S  E+  YYE   +  +LH++  PD+  R
Sbjct:  174 HIKRPMNAFMVWARDERRKILKAYPDMHNSNISKILGSRWKGMSNSEKQPYYEEQSRLSKLHMEQHPDYRYR 245
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Fly
Match: pan (gene:FBgn0085432 transcript:FBtr0308615)

HSP 1 Score: 162.925 bits (411), Expect = 1.906e-42
Identity = 77/145 (53.10%), Postives = 97/145 (66.90%), Query Frame = 3 
Query: 1143 DSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            D  KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH L REEQ+KYYE+A++E+QLH+Q++PDWS+R N    S+ KK++R  D                             ++  NNMKKCRAR+G++Q SQW
Sbjct:  267 DKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALGREEQAKYYELARRERQLHMQMYPDWSSRTNA---SRGKKRKRKQDT----------------------------NDGGNNMKKCRARFGLDQQSQW 380
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Fly
Match: pan (gene:FBgn0085432 transcript:FBtr0100246)

HSP 1 Score: 160.999 bits (406), Expect = 2.049e-42
Identity = 77/145 (53.10%), Postives = 97/145 (66.90%), Query Frame = 3 
Query: 1143 DSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            D  KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH L REEQ+KYYE+A++E+QLH+Q++PDWS+R N    S+ KK++R  D                             ++  NNMKKCRAR+G++Q SQW
Sbjct:  267 DKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALGREEQAKYYELARRERQLHMQMYPDWSSRTNA---SRGKKRKRKQDT----------------------------NDGGNNMKKCRARFGLDQQSQW 380
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Fly
Match: pan (gene:FBgn0085432 transcript:FBtr0100245)

HSP 1 Score: 163.696 bits (413), Expect = 2.324e-41
Identity = 77/145 (53.10%), Postives = 97/145 (66.90%), Query Frame = 3 
Query: 1143 DSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            D  KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH L REEQ+KYYE+A++E+QLH+Q++PDWS+R N    S+ KK++R  D                             ++  NNMKKCRAR+G++Q SQW
Sbjct:  267 DKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALGREEQAKYYELARRERQLHMQMYPDWSSRTNA---SRGKKRKRKQDT----------------------------NDGGNNMKKCRARFGLDQQSQW 380
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Fly
Match: pan (gene:FBgn0085432 transcript:FBtr0334301)

HSP 1 Score: 160.999 bits (406), Expect = 1.682e-40
Identity = 80/152 (52.63%), Postives = 93/152 (61.18%), Query Frame = 3 
Query: 1143 DSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSND-------NNNMKKCRARYGIEQMSQW 1577
            D  KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQSKYYE A++E+QLH++L+P WSARDNY                                  GYV     +  D        NNMKKCRAR+G++Q SQW
Sbjct:  267 DKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNY----------------------------------GYVSKKKKRKKDRSTTDSGGNNMKKCRARFGLDQQSQW 384
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Fly
Match: pan (gene:FBgn0085432 transcript:FBtr0089161)

HSP 1 Score: 160.999 bits (406), Expect = 1.955e-40
Identity = 80/152 (52.63%), Postives = 93/152 (61.18%), Query Frame = 3 
Query: 1143 DSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSND-------NNNMKKCRARYGIEQMSQW 1577
            D  KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQSKYYE A++E+QLH++L+P WSARDNY                                  GYV     +  D        NNMKKCRAR+G++Q SQW
Sbjct:  267 DKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNY----------------------------------GYVSKKKKRKKDRSTTDSGGNNMKKCRARFGLDQQSQW 384
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Zebrafish
Match: tcf7l2 (transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB-GENE-991110-8])

HSP 1 Score: 152.525 bits (384), Expect = 2.672e-39
Identity = 78/146 (53.42%), Postives = 98/146 (67.12%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKS----NDNNNMKKCRARYGIEQMSQW 1577
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY    K K++++  +               G     Y  N  C S     D +  KKCRAR+G++Q + W
Sbjct:  291 QPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKQAGE---------------GNEHREYFPNP-CLSLPPITDLSAPKKCRARFGLDQQNNW 420
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Zebrafish
Match: tcf7l2 (transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB-GENE-991110-8])

HSP 1 Score: 152.525 bits (384), Expect = 3.082e-39
Identity = 78/146 (53.42%), Postives = 98/146 (67.12%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKS----NDNNNMKKCRARYGIEQMSQW 1577
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY    K K++++  +               G     Y  N  C S     D +  KKCRAR+G++Q + W
Sbjct:  291 QPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKQAGE---------------GNEHREYFPNP-CLSLPPITDLSAPKKCRARFGLDQQNNW 420
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Zebrafish
Match: tcf7l2 (transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB-GENE-991110-8])

HSP 1 Score: 155.221 bits (391), Expect = 4.760e-39
Identity = 73/142 (51.41%), Postives = 90/142 (63.38%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY                             G  +    +    + ND N  KKCRA +G++Q+  W
Sbjct:  350 QPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNY-----------------------------GKKKKRKREKQAGEGNDANTPKKCRALFGLDQLGLW 462
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Zebrafish
Match: tcf7l2 (transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB-GENE-991110-8])

HSP 1 Score: 152.91 bits (385), Expect = 5.706e-39
Identity = 78/146 (53.42%), Postives = 98/146 (67.12%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKS----NDNNNMKKCRARYGIEQMSQW 1577
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY    K K++++  +               G     Y  N  C S     D +  KKCRAR+G++Q + W
Sbjct:  330 QPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKQAGE---------------GNEHREYFPNP-CLSLPPITDLSAPKKCRARFGLDQQNNW 459
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Zebrafish
Match: tcf7l2 (transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB-GENE-991110-8])

HSP 1 Score: 152.525 bits (384), Expect = 5.979e-39
Identity = 78/146 (53.42%), Postives = 98/146 (67.12%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKS----NDNNNMKKCRARYGIEQMSQW 1577
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY    K K++++  +               G     Y  N  C S     D +  KKCRAR+G++Q + W
Sbjct:  325 QPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKQAGE---------------GNEHREYFPNP-CLSLPPITDLSAPKKCRARFGLDQQNNW 454
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Xenopus
Match: tcf7 (transcription factor 7 [Source:NCBI gene;Acc:395061])

HSP 1 Score: 153.68 bits (387), Expect = 6.188e-40
Identity = 78/142 (54.93%), Postives = 96/142 (67.61%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQSKYYE+A+KE+QLH+QL+P WSARDNY      K+KRR                    ++  + D+    S+D  + KKCRAR+G+ Q + W
Sbjct:  247 KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQSKYYELARKERQLHMQLYPGWSARDNYG-----KRKRR--------------------TREKHQDS----SSDPGSPKKCRARFGLNQQTDW 359
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Xenopus
Match: tcf7 (transcription factor 7 [Source:NCBI gene;Acc:395061])

HSP 1 Score: 155.221 bits (391), Expect = 7.552e-40
Identity = 77/142 (54.23%), Postives = 93/142 (65.49%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQSKYYE+A+KE+QLH+QL+P WSARDNY      K+KRR  + +                           S+D  + KKCRAR+G+ Q + W
Sbjct:  247 KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQSKYYELARKERQLHMQLYPGWSARDNYG-----KRKRRTREKHQDS------------------------SSDPGSPKKCRARFGLNQQTDW 359
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Xenopus
Match: tcf7 (transcription factor 7 [Source:NCBI gene;Acc:395061])

HSP 1 Score: 155.992 bits (393), Expect = 8.658e-40
Identity = 77/142 (54.23%), Postives = 93/142 (65.49%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQSKYYE+A+KE+QLH+QL+P WSARDNY      K+KRR  + +                           S+D  + KKCRAR+G+ Q + W
Sbjct:  276 KPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQSKYYELARKERQLHMQLYPGWSARDNYG-----KRKRRTREKHQDS------------------------SSDPGSPKKCRARFGLNQQTDW 388
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Xenopus
Match: lef1 (lymphoid enhancer binding factor 1 [Source:NCBI gene;Acc:100493178])

HSP 1 Score: 144.821 bits (364), Expect = 4.914e-37
Identity = 61/78 (78.21%), Postives = 71/78 (91.03%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY 
Sbjct:  268 RPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG 345
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Xenopus
Match: lef1 (lymphoid enhancer binding factor 1 [Source:NCBI gene;Acc:100493178])

HSP 1 Score: 144.436 bits (363), Expect = 8.212e-37
Identity = 61/77 (79.22%), Postives = 71/77 (92.21%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNY 1382
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY
Sbjct:  281 RPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNY 357
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Mouse
Match: Tcf7 (transcription factor 7, T cell specific [Source:MGI Symbol;Acc:MGI:98507])

HSP 1 Score: 144.05 bits (362), Expect = 8.205e-39
Identity = 67/92 (72.83%), Postives = 78/92 (84.78%), Query Frame = 3 
Query: 1140 KDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR 1415
            K++ KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY      KKKRR
Sbjct:   91 KEAKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKRR 177
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Mouse
Match: Tcf7 (transcription factor 7, T cell specific [Source:MGI Symbol;Acc:MGI:98507])

HSP 1 Score: 145.976 bits (367), Expect = 3.758e-38
Identity = 67/92 (72.83%), Postives = 78/92 (84.78%), Query Frame = 3 
Query: 1140 KDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR 1415
            K++ KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY      KKKRR
Sbjct:  181 KEAKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKRR 267
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Mouse
Match: Lef1 (lymphoid enhancer binding factor 1 [Source:MGI Symbol;Acc:MGI:96770])

HSP 1 Score: 146.747 bits (369), Expect = 4.032e-38
Identity = 61/78 (78.21%), Postives = 71/78 (91.03%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY 
Sbjct:  228 RPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG 305
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Mouse
Match: Lef1 (lymphoid enhancer binding factor 1 [Source:MGI Symbol;Acc:MGI:96770])

HSP 1 Score: 145.206 bits (365), Expect = 2.863e-37
Identity = 61/78 (78.21%), Postives = 71/78 (91.03%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY 
Sbjct:  266 RPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG 343
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Mouse
Match: Lef1 (lymphoid enhancer binding factor 1 [Source:MGI Symbol;Acc:MGI:96770])

HSP 1 Score: 145.591 bits (366), Expect = 3.387e-37
Identity = 61/78 (78.21%), Postives = 71/78 (91.03%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY 
Sbjct:  294 RPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG 371
[Close]
BLAST of Transcription factor 7-like 1 vs. UniProt/SwissProt
Match: sp|P91943|PANG1_DROME (Protein pangolin, isoforms A/H/I/S OS=Drosophila melanogaster OX=7227 GN=pan PE=1 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 2.345e-39
Identity = 80/152 (52.63%), Postives = 93/152 (61.18%), Query Frame = 3 
Query: 1143 DSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSND-------NNNMKKCRARYGIEQMSQW 1577
            D  KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQSKYYE A++E+QLH++L+P WSARDNY                                  GYV     +  D        NNMKKCRAR+G++Q SQW
Sbjct:  267 DKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNY----------------------------------GYVSKKKKRKKDRSTTDSGGNNMKKCRARFGLDQQSQW 384
[Close]
BLAST of Transcription factor 7-like 1 vs. UniProt/SwissProt
Match: sp|Q8IMA8|PANG2_DROME (Protein pangolin, isoform J OS=Drosophila melanogaster OX=7227 GN=pan PE=1 SV=2)

HSP 1 Score: 161.384 bits (407), Expect = 4.715e-39
Identity = 80/152 (52.63%), Postives = 93/152 (61.18%), Query Frame = 3 
Query: 1143 DSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSND-------NNNMKKCRARYGIEQMSQW 1577
            D  KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQSKYYE A++E+QLH++L+P WSARDNY                                  GYV     +  D        NNMKKCRAR+G++Q SQW
Sbjct:  708 DKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNY----------------------------------GYVSKKKKRKKDRSTTDSGGNNMKKCRARFGLDQQSQW 825
[Close]
BLAST of Transcription factor 7-like 1 vs. UniProt/SwissProt
Match: sp|P36402|TCF7_HUMAN (Transcription factor 7 OS=Homo sapiens OX=9606 GN=TCF7 PE=1 SV=3)

HSP 1 Score: 145.976 bits (367), Expect = 1.480e-36
Identity = 68/98 (69.39%), Postives = 80/98 (81.63%), Query Frame = 3 
Query: 1122 CKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR 1415
             +S   K++ KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY      KKKRR
Sbjct:  256 AESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG-----KKKRR 348
[Close]
BLAST of Transcription factor 7-like 1 vs. UniProt/SwissProt
Match: sp|Q9QXN1|LEF1_RAT (Lymphoid enhancer-binding factor 1 OS=Rattus norvegicus OX=10116 GN=Lef1 PE=2 SV=1)

HSP 1 Score: 145.976 bits (367), Expect = 2.176e-36
Identity = 61/78 (78.21%), Postives = 71/78 (91.03%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY 
Sbjct:  294 RPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG 371
[Close]
BLAST of Transcription factor 7-like 1 vs. UniProt/SwissProt
Match: sp|P27782|LEF1_MOUSE (Lymphoid enhancer-binding factor 1 OS=Mus musculus OX=10090 GN=Lef1 PE=1 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 2.369e-36
Identity = 61/78 (78.21%), Postives = 71/78 (91.03%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            +PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY 
Sbjct:  294 RPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG 371
[Close]
BLAST of Transcription factor 7-like 1 vs. TrEMBL
Match: A0A291LM05 (TCF-3 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1038.1 bits (2683), Expect = 0.000e+0
Identity = 635/654 (97.09%), Postives = 635/654 (97.09%), Query Frame = 3 
Query:  123 MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMFEHLWHSLPPGPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLXXXXXXXXXXXXXXXNIKVEXXXXXXXXXXXXXQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWXXXXXXXXXXXXFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTXXXXXXXXXXXXXXXXXXXXXXVNQEKLNSTQLITI 2084
            MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMFEHLWHSLPPGPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVVTGSESSSSSIATTSTTVIASTSSNSTLTTSKDTLNSNGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLSNISVASSTTSSCITNIKVEKSNNTHSKNNNKKQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR                   LSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWCKPCRRKKKCIRFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTNSEFSSNIIPSPSSAFSSLKSSVNQEKLNSTQLITI
Sbjct:    1 MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMFEHLWHSLPPGPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVVTGSESSSSSIATTSTTVIASTSSNSTLTTSKDTLNSNGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLSNISVASSTTSSCITNIKVEKSNNTHSKNNNKKQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR-------------------LSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWCKPCRRKKKCIRFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTNSEFSSNIIPSPSSAFSSLKSSVNQEKLNSTQLITI 635
[Close]
BLAST of Transcription factor 7-like 1 vs. TrEMBL
Match: A0A423TF02 (HMG box domain-containing protein OS=Penaeus vannamei OX=6689 GN=C7M84_006431 PE=4 SV=1)

HSP 1 Score: 169.859 bits (429), Expect = 6.553e-44
Identity = 100/189 (52.91%), Postives = 127/189 (67.20%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWXXXXXXXXXXXXFLKNDDNDMIA---KDSKHITFQKSKDSSIYDLDS 1709
            KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG+KWH LSREEQ+KYYE+A+KE+QLH+Q++P WS+R NY   S+ KKK+R  D                            K+ D  NMKKCRARYG+EQ SQWCKPCRRKKKCIR+++ ++ + +A    DS   + +  ++  + D+ S
Sbjct:   10 KPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHALSREEQAKYYEMARKERQLHMQMYPGWSSRQNY---SQGKKKKRNRD----------------------------KTQDGANMKKCRARYGLEQQSQWCKPCRRKKKCIRYMEGEEGEDMAPGSADSVDASQESEEEDDLQDMSS 167
[Close]
BLAST of Transcription factor 7-like 1 vs. TrEMBL
Match: A0A183SW48 (HMG box domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS8446 PE=4 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 1.163e-43
Identity = 92/161 (57.14%), Postives = 107/161 (66.46%), Query Frame = 3 
Query: 1158 HIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMF-------------DXXXXXXXXXXXXCFSGLSQTG-YVDNTDCKS-------NDNNNMKKCRARYGIEQMSQW 1577
            HIKKPLNAFMLFMKEMR  +QEECTLKESAAINQILGKKWH LS+ EQSKYYE+A+KEK++H QLFP WSARDNYAIHSK K+KR++                N       I +   GL+  G Y  N+   S        D  N KKCRAR+G+EQ S+W
Sbjct:  148 HIKKPLNAFMLFMKEMRPKIQEECTLKESAAINQILGKKWHELSKPEQSKYYEMARKEKEIHRQLFPGWSARDNYAIHSKRKRKRKLAAAAAAAAAAAAVNSVNRRGPGGEIYDGLDGLNSAGNYFQNSSLNSVVAVAAAVDLGNPKKCRARFGLEQQSRW 308
[Close]
BLAST of Transcription factor 7-like 1 vs. TrEMBL
Match: E0VI91 (T-cell specific transcription factor, tcf, putative OS=Pediculus humanus subsp. corporis OX=121224 GN=8237863 PE=4 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 2.067e-43
Identity = 86/163 (52.76%), Postives = 105/163 (64.42%), Query Frame = 3 
Query: 1098 DSLHELRFCKS---THHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            D  H +R  KS   +   D  KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH L REEQ+KYYE+A++E+QLH+QL+PDWS+R N +   K K+K+   D               G+            S D NNMKKCRARYG++Q SQW
Sbjct:   62 DHNHRIRDSKSQDASSQNDKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALGREEQAKYYELARRERQLHMQLYPDWSSRANSSRGKKRKRKQEAND---------------GVLLPTPPGRGRGPSYDRNNMKKCRARYGLDQQSQW 209
[Close]
BLAST of Transcription factor 7-like 1 vs. TrEMBL
Match: A0A0X3PXG7 (HMG box domain-containing protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR167471 PE=4 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 4.214e-43
Identity = 106/188 (56.38%), Postives = 125/188 (66.49%), Query Frame = 3 
Query: 1158 HIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXC-------------FSGLSQTG-YVDNTDCKS-------NDNNNMKKCRARYGIEQMSQWXXXXXXXXXXXXFLKNDDNDMIAKDSK 1658
            HIKKPLNAFMLFMKEMR  +QEECTLKESAAINQILGKKWH LS+ EQSKYYE+A+KEK++H QLFP WSARDNYAIHSK K+KR++         +   N                GL+  G Y  N+   S        D  N KKCRAR+G+EQ S+WCKPCRRKKKC+RFL + + D   +  K
Sbjct:  409 HIKKPLNAFMLFMKEMRPKIQEECTLKESAAINQILGKKWHELSKPEQSKYYEMARKEKEIHRQLFPGWSARDNYAIHSKRKRKRKLAAAAAAAAAAAAVNSVNRRGPGGEIYDGLDGLNSAGNYFQNSSLNSVVAVAAAVDLGNPKKCRARFGLEQQSRWCKPCRRKKKCVRFLTDTEYDEAVQSGK 596
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Cavefish
Match: tcf7l2 (transcription factor 7 like 2 [Source:NCBI gene;Acc:103031257])

HSP 1 Score: 155.221 bits (391), Expect = 4.340e-39
Identity = 73/141 (51.77%), Postives = 89/141 (63.12%), Query Frame = 3 
Query: 1155 PHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY                             G  +    +    + ND N  KKCRA +G++Q+  W
Sbjct:  350 PHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNY-----------------------------GKKKKRKREKQQAEGNDANTPKKCRALFGLDQLVLW 461
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Cavefish
Match: tcf7l2 (transcription factor 7 like 2 [Source:NCBI gene;Acc:103031257])

HSP 1 Score: 152.91 bits (385), Expect = 6.806e-39
Identity = 81/145 (55.86%), Postives = 99/145 (68.28%), Query Frame = 3 
Query: 1155 PHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKS----NDNNNMKKCRARYGIEQMSQW 1577
            PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNYA + + KKK+R  +               G     Y  N  C S     D +  KKCRAR+G++Q + W
Sbjct:  350 PHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYAANQQGKKKKRKREKQQA----------EGNEHREYFPNP-CLSLPPITDLSAPKKCRARFGLDQQNNW 483
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Cavefish
Match: tcf7l2 (transcription factor 7 like 2 [Source:NCBI gene;Acc:103031257])

HSP 1 Score: 154.066 bits (388), Expect = 1.100e-38
Identity = 77/141 (54.61%), Postives = 96/141 (68.09%), Query Frame = 3 
Query: 1155 PHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNYA + + KKK+R                          +    + ND +  KKCRAR+G++Q + W
Sbjct:  350 PHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYAANQQGKKKKRK------------------------REKQQAEGNDLSAPKKCRARFGLDQQNNW 466
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Cavefish
Match: tcf7l2 (transcription factor 7 like 2 [Source:NCBI gene;Acc:103031257])

HSP 1 Score: 153.68 bits (387), Expect = 1.564e-38
Identity = 81/145 (55.86%), Postives = 99/145 (68.28%), Query Frame = 3 
Query: 1155 PHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKS----NDNNNMKKCRARYGIEQMSQW 1577
            PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNYA + + KKK+R  +               G     Y  N  C S     D +  KKCRAR+G++Q + W
Sbjct:  330 PHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYAANQQGKKKKRKREKQQA----------EGNEHREYFPN-PCLSLPPITDLSAPKKCRARFGLDQQNNW 463
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Cavefish
Match: tcf7l2 (transcription factor 7 like 2 [Source:NCBI gene;Acc:103031257])

HSP 1 Score: 153.68 bits (387), Expect = 1.858e-38
Identity = 78/145 (53.79%), Postives = 96/145 (66.21%), Query Frame = 3 
Query: 1155 PHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKS----NDNNNMKKCRARYGIEQMSQW 1577
            PHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY    K K++++  +               G     Y  N  C S     D N  KKCRA +G++Q+  W
Sbjct:  350 PHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKQQAE---------------GNEHREYFPN-PCLSLPPITDANTPKKCRALFGLDQLVLW 478
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004973.1 (pep scaffold:Pmarinus_7.0:GL479925:4219:8952:-1 gene:ENSPMAG00000004519.1 transcript:ENSPMAT00000004973.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.4185 bits (202), Expect = 3.462e-19
Identity = 45/111 (40.54%), Postives = 68/111 (61.26%), Query Frame = 3 
Query: 1257 QILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDC----KSNDNNNMKKCRARYGIEQMSQW 1577
            QILG++WH LSREEQ+KYYE+A+KE+QLH QL+P WSARDNY    K K++++  +                + +  +++   C      ++  + KKCRARYG++Q + W
Sbjct:    1 QILGRRWHALSREEQAKYYELARKERQLHSQLYPGWSARDNYGKKKKRKREKQPAEQ-------------PAVIEPLHLNTRPCVKPSPPSEQESAKKCRARYGVDQQNNW 98
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006684.1 (pep scaffold:Pmarinus_7.0:GL477399:28105:35473:-1 gene:ENSPMAG00000006026.1 transcript:ENSPMAT00000006684.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 2.032e-11
Identity = 29/90 (32.22%), Postives = 57/90 (63.33%), Query Frame = 3 
Query: 1098 DSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMK-EMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDW 1364
            +S+ + R  + +  + S +PHIK+P+NAFM++ K E R+ +Q    +K +  I++  G +W ++S +E+  YYE   +  +LH++ +PD+
Sbjct:   40 NSMSDARVFRESRSRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMKHTLQISECPGSRWKSMSNQEKQPYYEEQARLSKLHLEKYPDY 129
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008165.1 (pep scaffold:Pmarinus_7.0:GL479973:18969:29522:-1 gene:ENSPMAG00000007384.1 transcript:ENSPMAT00000008165.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.6178 bits (148), Expect = 4.280e-11
Identity = 25/83 (30.12%), Postives = 52/83 (62.65%), Query Frame = 3 
Query: 1125 KSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSAR 1373
            +    + + +PHIK+P+NAFM++ K+ R+ + +      +++I++ILG +W  +S +E+  YYE   +  +LH++ +P +  R
Sbjct:   49 RDGRGRHAGEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKAMSSQEKQPYYEEQARLSKLHLERYPGYKYR 131
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Sea Lamprey
Match: sox10 (SRY-box transcription factor 10 [Source:ZFIN;Acc:ZDB-GENE-011207-1])

HSP 1 Score: 53.1434 bits (126), Expect = 1.113e-7
Identity = 22/71 (30.99%), Postives = 44/71 (61.97%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDW 1364
            KPH+K+P+NAFM++ +  R+ + ++     +A +++ LGK W  L+  E+  + E A++ +  H +  PD+
Sbjct:  109 KPHVKRPMNAFMVWAQAARRKLSDQYPQLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRMQHKKDHPDY 179
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010223.1 (pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 gene:ENSPMAG00000009255.1 transcript:ENSPMAT00000010223.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.1358 bits (113), Expect = 2.990e-7
Identity = 23/74 (31.08%), Postives = 45/74 (60.81%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSAR 1373
            +P I +P+NAFM++ K+ R+ + ++     +A ++++LGK W  L+ E +    E A++ + LH+   PD+  R
Sbjct:    3 EPRIPRPMNAFMVWAKDERRRLAKQNPDLHNAELSKMLGKSWRALTPESRRPCVEEAERLRLLHLSEHPDYKYR 76
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Nematostella
Match: EDO32618 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUJ9])

HSP 1 Score: 127.872 bits (320), Expect = 6.924e-35
Identity = 59/76 (77.63%), Postives = 67/76 (88.16%), Query Frame = 3 
Query: 1158 HIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            HIKKPLNAFML+MK+MR  V  ECTLKESAAINQILGKKWH L R EQ+KYYE+A+KE+ LH+QL+P WSARDNYA
Sbjct:   11 HIKKPLNAFMLYMKDMRPKVVAECTLKESAAINQILGKKWHALDRSEQAKYYEMARKERALHLQLYPGWSARDNYA 86
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Nematostella
Match: EDO47688 (Predicted protein; Sox family protein 2 [Source:UniProtKB/TrEMBL;Acc:Q3S383])

HSP 1 Score: 60.8474 bits (146), Expect = 3.014e-10
Identity = 26/72 (36.11%), Postives = 50/72 (69.44%), Query Frame = 3 
Query: 1149 PKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDW 1364
            P  HIK+P+NA+M++ ++ R+ + EEC    ++ I++ LG +W++L+ +E+  Y E AK+ ++LH +  PD+
Sbjct:    4 PGDHIKRPMNAYMVWSRKERRRIAEECPRMLNSEISKRLGLEWNSLTLDEKQPYVEEAKRLRELHKKDHPDY 75
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Nematostella
Match: EDO32843 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STW6])

HSP 1 Score: 52.373 bits (124), Expect = 1.301e-8
Identity = 28/83 (33.73%), Postives = 51/83 (61.45%), Query Frame = 3 
Query: 1122 CKSTHH--KDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDW 1364
             ++TH   K S   H+K+P+NAFM++ +  R+ + EE     +A I++ LGK+W  LS  E+  + E +++ +  H+Q +PD+
Sbjct:    8 TQATHESKKKSDMQHVKRPMNAFMVWSQIERRKMAEEHPDMHNAEISKRLGKRWKLLSESEKRPFVEESERLRIRHMQAYPDY 90
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Nematostella
Match: EDO33516 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRZ8])

HSP 1 Score: 51.2174 bits (121), Expect = 3.433e-8
Identity = 26/68 (38.24%), Postives = 44/68 (64.71%), Query Frame = 3 
Query: 1161 IKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDW 1364
            IK+PLNAF+L+ K+ R+ +  E     +  I++ LG +W  L+ EE++ Y+E AKK K+ H + +P +
Sbjct:    6 IKRPLNAFILWSKKRRRVIANENPQMHNFDISRKLGLEWQKLTEEEKAYYFEEAKKLKEEHKERYPHY 73
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Nematostella
Match: EDO36144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJD9])

HSP 1 Score: 51.2174 bits (121), Expect = 3.940e-8
Identity = 26/66 (39.39%), Postives = 42/66 (63.64%), Query Frame = 3 
Query: 1164 KKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPD 1361
            K+P+NAFMLF K  R  + +    K++ AI+ ILG KW ++ +EE+ +Y   AK+  + H ++ PD
Sbjct:   13 KRPMNAFMLFAKRYRLEITQAHPGKDNRAISVILGDKWKSMKQEERKQYVMEAKQLAEEHKKVNPD 78
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Medaka
Match: lef1 (lymphoid enhancer binding factor 1 [Source:NCBI gene;Acc:101167344])

HSP 1 Score: 145.591 bits (366), Expect = 1.818e-37
Identity = 62/78 (79.49%), Postives = 71/78 (91.03%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY 
Sbjct:  267 KPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG 344
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Medaka
Match: lef1 (lymphoid enhancer binding factor 1 [Source:NCBI gene;Acc:101167344])

HSP 1 Score: 145.591 bits (366), Expect = 2.114e-37
Identity = 62/78 (79.49%), Postives = 71/78 (91.03%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYA 1385
            KPHIKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH LSREEQ+KYYE+A+KE+QLH+QL+P WSARDNY 
Sbjct:  261 KPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG 338
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Medaka
Match: tcf7 (transcription factor 7 [Source:NCBI gene;Acc:101162309])

HSP 1 Score: 146.362 bits (368), Expect = 1.049e-36
Identity = 73/146 (50.00%), Postives = 94/146 (64.38%), Query Frame = 3 
Query: 1140 KDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            K+  KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH L+REEQ+KYYE+A+KE+QLH+QL+P WSARDNY             +  +  +    N    G  +    +     + D  + KKCRAR+G+ Q + W
Sbjct:  246 KEPKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALTREEQAKYYELARKERQLHMQLYPTWSARDNY-------------EAGLSGVAGEKNKADWGKKKRRKREKQQDSNTDPGSPKKCRARFGLNQQTDW 378
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Medaka
Match: tcf7 (transcription factor 7 [Source:NCBI gene;Acc:101162309])

HSP 1 Score: 146.362 bits (368), Expect = 1.231e-36
Identity = 72/146 (49.32%), Postives = 90/146 (61.64%), Query Frame = 3 
Query: 1140 KDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            K+  KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH L+REEQ+KYYE+A+KE+QLH+QL+P WSARDNY                             G  +    +     + D  + KKCRAR+G+ Q + W
Sbjct:  276 KEPKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALTREEQAKYYELARKERQLHMQLYPTWSARDNY-----------------------------GKKKRRKREKQQDSNTDPGSPKKCRARFGLNQQTDW 392
[Close]
BLAST of Transcription factor 7-like 1 vs. Ensembl Medaka
Match: tcf7 (transcription factor 7 [Source:NCBI gene;Acc:101162309])

HSP 1 Score: 146.747 bits (369), Expect = 1.246e-36
Identity = 73/146 (50.00%), Postives = 94/146 (64.38%), Query Frame = 3 
Query: 1140 KDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQW 1577
            K+  KP IKKPLNAFML+MKEMR  V  ECTLKESAAINQILG++WH L+REEQ+KYYE+A+KE+QLH+QL+P WSARDNY             +  +  +    N    G  +    +     + D  + KKCRAR+G+ Q + W
Sbjct:  276 KEPKKPVIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALTREEQAKYYELARKERQLHMQLYPTWSARDNY-------------EAGLSGVAGEKNKADWGKKKRRKREKQQDSNTDPGSPKKCRARFGLNQQTDW 408
[Close]
BLAST of Transcription factor 7-like 1 vs. Planmine SMEST
Match: SMESG000038786.1 (SMESG000038786.1)

HSP 1 Score: 1038.1 bits (2683), Expect = 0.000e+0
Identity = 635/654 (97.09%), Postives = 635/654 (97.09%), Query Frame = 3 
Query:  123 MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMFEHLWHSLPPGPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLXXXXXXXXXXXXXXXNIKVEXXXXXXXXXXXXXQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWXXXXXXXXXXXXFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTXXXXXXXXXXXXXXXXXXXXXXVNQEKLNSTQLITI 2084
            MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMFEHLWHSLPPGPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVVTGSESSSSSIATTSTTVIASTSSNSTLTTSKDTLNSNGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLSNISVASSTTSSCITNIKVEKSNNTHSKNNNKKQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR                   LSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWCKPCRRKKKCIRFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTNSEFSSNIIPSPSSAFSSLKSSVNQEKLNSTQLITI
Sbjct:    1 MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMFEHLWHSLPPGPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVVTGSESSSSSIATTSTTVIASTSSNSTLTTSKDTLNSNGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLSNISVASSTTSSCITNIKVEKSNNTHSKNNNKKQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR-------------------LSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWCKPCRRKKKCIRFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTNSEFSSNIIPSPSSAFSSLKSSVNQEKLNSTQLITI 635
[Close]
BLAST of Transcription factor 7-like 1 vs. Planmine SMEST
Match: SMESG000038786.1 (SMESG000038786.1)

HSP 1 Score: 1009.59 bits (2609), Expect = 0.000e+0
Identity = 626/654 (95.72%), Postives = 626/654 (95.72%), Query Frame = 3 
Query:  123 MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMFEHLWHSLPPGPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLXXXXXXXXXXXXXXXNIKVEXXXXXXXXXXXXXQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXCFSGLSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWXXXXXXXXXXXXFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTXXXXXXXXXXXXXXXXXXXXXXVNQEKLNSTQLITI 2084
            MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMF         GPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVVTGSESSSSSIATTSTTVIASTSSNSTLTTSKDTLNSNGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLSNISVASSTTSSCITNIKVEKSNNTHSKNNNKKQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR                   LSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWCKPCRRKKKCIRFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTNSEFSSNIIPSPSSAFSSLKSSVNQEKLNSTQLITI
Sbjct:    1 MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPFMPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMF---------GPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVVTGSESSSSSIATTSTTVIASTSSNSTLTTSKDTLNSNGLMYVPSPLKPTPINLSTYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLSNISVASSTTSSCITNIKVEKSNNTHSKNNNKKQDSLHELRFCKSTHHKDSPKPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRR-------------------LSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWCKPCRRKKKCIRFLKNDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSPQGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGKIEPTIKGLEQSNSASTNTNSEFSSNIIPSPSSAFSSLKSSVNQEKLNSTQLITI 626
[Close]
BLAST of Transcription factor 7-like 1 vs. Planmine SMEST
Match: SMESG000017328.1 (SMESG000017328.1)

HSP 1 Score: 172.17 bits (435), Expect = 8.134e-44
Identity = 109/218 (50.00%), Postives = 137/218 (62.84%), Query Frame = 3 
Query: 1143 DSPK-PHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXC------FSGLSQTGYVD-----------NTDCKSNDN-------------------------------NNMKKCRARYGIEQMSQWXXXXXXXXXXXXFLKNDDNDMIAK 1649
            DSPK PHIKKPLNAFMLFMKEMR  VQEECTLKESAAINQILGKKWH LSRE+Q+KYYE+A+KEK+LH QL+P WSARDNYA H+K +KKR++ +++++       +         G + +GY D           NTD  S +N                               +N KKCRAR+G+E  + WCKPCRRKKKC+RF+ N  +D +A+
Sbjct:  375 DSPKKPHIKKPLNAFMLFMKEMRPKVQEECTLKESAAINQILGKKWHELSREDQTKYYELARKEKELHQQLYPGWSARDNYASHAKRRKKRKLLNSSMLNSRDGFLSMNMMPMNHYGPNNSGYGDRHPCDMRTNRSNTDSGSRNNSMDILMCNETGRRPNGASIQGMHASGPTTNGSNPKKCRARFGLEHQNLWCKPCRRKKKCVRFIYNTTDDSLAE 592

HSP 2 Score: 82.4185 bits (202), Expect = 1.107e-15
Identity = 57/128 (44.53%), Postives = 76/128 (59.38%), Query Frame = 3 
Query:  123 MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDA-VFNAP------FADYLFPPYPGSYAAAFSQDSSFT-SKVPFMPP---NPGTFGFMPFSMRD 473
            M  + +SS++ T  DEV+VYKDEG+EE E+ +S+ENL EDKV LV EGE++ PL F DI+   Y A +F  P      FA+Y    Y G Y    S  S+F  +K+P M     NP  F F+PF + D
Sbjct:    1 MPHMNSSSDDLTFTDEVKVYKDEGDEE-EQEKSAENLKEDKVGLVNEGEEKTPLEF-DIYNKQYAASMFKVPFSTDPRFANYFMSNYSG-YMNGSSNPSTFMGNKMPLMSSSVQNP--FNFIPFPIHD 123
[Close]
BLAST of Transcription factor 7-like 1 vs. Planmine SMEST
Match: SMESG000017328.1 (SMESG000017328.1)

HSP 1 Score: 172.17 bits (435), Expect = 8.805e-44
Identity = 109/218 (50.00%), Postives = 137/218 (62.84%), Query Frame = 3 
Query: 1143 DSPK-PHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDXXXXXXXXXXXXC------FSGLSQTGYVD-----------NTDCKSNDN-------------------------------NNMKKCRARYGIEQMSQWXXXXXXXXXXXXFLKNDDNDMIAK 1649
            DSPK PHIKKPLNAFMLFMKEMR  VQEECTLKESAAINQILGKKWH LSRE+Q+KYYE+A+KEK+LH QL+P WSARDNYA H+K +KKR++ +++++       +         G + +GY D           NTD  S +N                               +N KKCRAR+G+E  + WCKPCRRKKKC+RF+ N  +D +A+
Sbjct:  372 DSPKKPHIKKPLNAFMLFMKEMRPKVQEECTLKESAAINQILGKKWHELSREDQTKYYELARKEKELHQQLYPGWSARDNYASHAKRRKKRKLLNSSMLNSRDGFLSMNMMPMNHYGPNNSGYGDRHPCDMRTNRSNTDSGSRNNSMDILMCNETGRRPNGASIQGMHASGPTTNGSNPKKCRARFGLEHQNLWCKPCRRKKKCVRFIYNTTDDSLAE 589

HSP 2 Score: 80.8777 bits (198), Expect = 3.027e-15
Identity = 56/122 (45.90%), Postives = 73/122 (59.84%), Query Frame = 3 
Query:  141 SSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGEDQKPLNFSDIFRPSYDA-VFNAP------FADYLFPPYPGSYAAAFSQDSSFT-SKVPFMPP---NPGTFGFMPFSMRD 473
            SS++ T  DEV+VYKDEG+EE E+ +S+ENL EDKV LV EGE++ PL F DI+   Y A +F  P      FA+Y    Y G Y    S  S+F  +K+P M     NP  F F+PF + D
Sbjct:    4 SSDDLTFTDEVKVYKDEGDEE-EQEKSAENLKEDKVGLVNEGEEKTPLEF-DIYNKQYAASMFKVPFSTDPRFANYFMSNYSG-YMNGSSNPSTFMGNKMPLMSSSVQNP--FNFIPFPIHD 120
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BLAST of Transcription factor 7-like 1 vs. Planmine SMEST
Match: SMESG000052392.1 (SMESG000052392.1)

HSP 1 Score: 153.295 bits (386), Expect = 1.456e-39
Identity = 68/87 (78.16%), Postives = 78/87 (89.66%), Query Frame = 3 
Query: 1152 KPHIKKPLNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIAKKEKQLHIQLFPDWSARDNYAIHSKHKKKR 1412
            K HIKKPLNAFMLFMKEMR  V  ECTLKESAAINQILG++WH L+REEQ+KYYE+A+KEK+LH QL+P+WSARDNYA H+K KKKR
Sbjct:  226 KTHIKKPLNAFMLFMKEMRSRVVAECTLKESAAINQILGRRWHALTREEQTKYYEMARKEKELHQQLYPNWSARDNYASHTKRKKKR 312
The following BLAST results are available for this feature:
BLAST of Transcription factor 7-like 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TCF71.397e-4154.11transcription factor 7 [Source:HGNC Symbol;Acc:HGN... [more]
TCF72.060e-4052.63transcription factor 7 [Source:HGNC Symbol;Acc:HGN... [more]
TCF79.152e-4069.39transcription factor 7 [Source:HGNC Symbol;Acc:HGN... [more]
TCF71.448e-3969.39transcription factor 7 [Source:HGNC Symbol;Acc:HGN... [more]
TCF71.564e-3869.39transcription factor 7 [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pop-11.595e-2542.25pep chromosome:WBcel235:I:2823254:2830311:-1 gene:... [more]
gei-31.712e-1133.80GEX Interacting protein [Source:UniProtKB/TrEMBL;... [more]
gei-32.215e-1133.80GEX Interacting protein [Source:UniProtKB/TrEMBL;... [more]
egl-131.672e-831.71Transcription factor egl-13 [Source:UniProtKB/Swi... [more]
egl-131.789e-833.33Transcription factor egl-13 [Source:UniProtKB/Swi... [more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pan1.906e-4253.10gene:FBgn0085432 transcript:FBtr0308615[more]
pan2.049e-4253.10gene:FBgn0085432 transcript:FBtr0100246[more]
pan2.324e-4153.10gene:FBgn0085432 transcript:FBtr0100245[more]
pan1.682e-4052.63gene:FBgn0085432 transcript:FBtr0334301[more]
pan1.955e-4052.63gene:FBgn0085432 transcript:FBtr0089161[more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tcf7l22.672e-3953.42transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB... [more]
tcf7l23.082e-3953.42transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB... [more]
tcf7l24.760e-3951.41transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB... [more]
tcf7l25.706e-3953.42transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB... [more]
tcf7l25.979e-3953.42transcription factor 7 like 2 [Source:ZFIN;Acc:ZDB... [more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tcf76.188e-4054.93transcription factor 7 [Source:NCBI gene;Acc:39506... [more]
tcf77.552e-4054.23transcription factor 7 [Source:NCBI gene;Acc:39506... [more]
tcf78.658e-4054.23transcription factor 7 [Source:NCBI gene;Acc:39506... [more]
lef14.914e-3778.21lymphoid enhancer binding factor 1 [Source:NCBI ge... [more]
lef18.212e-3779.22lymphoid enhancer binding factor 1 [Source:NCBI ge... [more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tcf78.205e-3972.83transcription factor 7, T cell specific [Source:MG... [more]
Tcf73.758e-3872.83transcription factor 7, T cell specific [Source:MG... [more]
Lef14.032e-3878.21lymphoid enhancer binding factor 1 [Source:MGI Sym... [more]
Lef12.863e-3778.21lymphoid enhancer binding factor 1 [Source:MGI Sym... [more]
Lef13.387e-3778.21lymphoid enhancer binding factor 1 [Source:MGI Sym... [more]
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BLAST of Transcription factor 7-like 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P91943|PANG1_DROME2.345e-3952.63Protein pangolin, isoforms A/H/I/S OS=Drosophila m... [more]
sp|Q8IMA8|PANG2_DROME4.715e-3952.63Protein pangolin, isoform J OS=Drosophila melanoga... [more]
sp|P36402|TCF7_HUMAN1.480e-3669.39Transcription factor 7 OS=Homo sapiens OX=9606 GN=... [more]
sp|Q9QXN1|LEF1_RAT2.176e-3678.21Lymphoid enhancer-binding factor 1 OS=Rattus norve... [more]
sp|P27782|LEF1_MOUSE2.369e-3678.21Lymphoid enhancer-binding factor 1 OS=Mus musculus... [more]
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BLAST of Transcription factor 7-like 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A291LM050.000e+097.09TCF-3 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
A0A423TF026.553e-4452.91HMG box domain-containing protein OS=Penaeus vanna... [more]
A0A183SW481.163e-4357.14HMG box domain-containing protein OS=Schistocephal... [more]
E0VI912.067e-4352.76T-cell specific transcription factor, tcf, putativ... [more]
A0A0X3PXG74.214e-4356.38HMG box domain-containing protein (Fragment) OS=Sc... [more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tcf7l24.340e-3951.77transcription factor 7 like 2 [Source:NCBI gene;Ac... [more]
tcf7l26.806e-3955.86transcription factor 7 like 2 [Source:NCBI gene;Ac... [more]
tcf7l21.100e-3854.61transcription factor 7 like 2 [Source:NCBI gene;Ac... [more]
tcf7l21.564e-3855.86transcription factor 7 like 2 [Source:NCBI gene;Ac... [more]
tcf7l21.858e-3853.79transcription factor 7 like 2 [Source:NCBI gene;Ac... [more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000004973.13.462e-1940.54pep scaffold:Pmarinus_7.0:GL479925:4219:8952:-1 ge... [more]
ENSPMAT00000006684.12.032e-1132.22pep scaffold:Pmarinus_7.0:GL477399:28105:35473:-1 ... [more]
ENSPMAT00000008165.14.280e-1130.12pep scaffold:Pmarinus_7.0:GL479973:18969:29522:-1 ... [more]
sox101.113e-730.99SRY-box transcription factor 10 [Source:ZFIN;Acc:Z... [more]
ENSPMAT00000010223.12.990e-731.08pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 ge... [more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transcription factor 7-like 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO326186.924e-3577.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO476883.014e-1036.11Predicted protein; Sox family protein 2 [Source:U... [more]
EDO328431.301e-833.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO335163.433e-838.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361443.940e-839.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Transcription factor 7-like 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lef11.818e-3779.49lymphoid enhancer binding factor 1 [Source:NCBI ge... [more]
lef12.114e-3779.49lymphoid enhancer binding factor 1 [Source:NCBI ge... [more]
tcf71.049e-3650.00transcription factor 7 [Source:NCBI gene;Acc:10116... [more]
tcf71.231e-3649.32transcription factor 7 [Source:NCBI gene;Acc:10116... [more]
tcf71.246e-3650.00transcription factor 7 [Source:NCBI gene;Acc:10116... [more]
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BLAST of Transcription factor 7-like 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000038786.10.000e+097.09SMESG000038786.1[more]
SMESG000038786.10.000e+095.72SMESG000038786.1[more]
SMESG000017328.18.134e-4450.00SMESG000017328.1[more]
SMESG000017328.18.805e-4450.00SMESG000017328.1[more]
SMESG000052392.11.456e-3978.16SMESG000052392.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014712 ID=SMED30014712|Name=Transcription factor 7-like 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2726bp
ATATTTGTTATGCAATTAATTTATATAGTTTGTTTAGTTAACTTAGTTTT
GTTTTTTAATTTATAACATTTGTATGGCTACCCTAAAAAATTAATGTTAT
TCGAATTAAATTTTAATTTATTATGGCACAAATTGTAAATTCATCAGAGG
AATGTACATGTAAAGATGAAGTGAGAGTTTATAAAGATGAAGGAGAAGAA
GAGGATGAAAAAAATCGTTCATCAGAAAACTTGTCTGAAGATAAAGTTAA
TTTAGTGACAGAAGGTGAAGATCAGAAGCCATTGAATTTTAGTGATATAT
TTCGACCAAGTTATGATGCTGTTTTTAATGCACCATTTGCCGATTATCTT
TTTCCTCCATATCCTGGGTCTTATGCTGCCGCGTTTTCTCAAGATTCATC
ATTTACATCCAAAGTGCCTTTTATGCCTCCAAATCCGGGTACATTTGGTT
TTATGCCTTTCTCAATGCGAGATGCAATTGAGTCATGTGGATTAAACGGA
GCGTTAGGGTTTTCAAATGCATATCCATTTTCTTCCAGAAATGGATTTAT
GTTCGAACATCTTTGGCATTCGCTTCCTCCAGGACCTCACATATCTGCAT
TATGTTCGGAAAATTTTGCATCGATGTGGGCTAACTCGAATTCTCAGTCA
TTTTCATTACTTAATCCATTTATGTCTTCTGTAGCTTCATCAACAAACAA
TCCAGTAGTTACTGGGAGTGAATCAAGTTCATCATCAATTGCTACAACAT
CAACAACTGTTATCGCCTCAACTTCTTCAAACAGTACTCTCACAACTAGT
AAAGATACACTGAATTCTAATGGTCTCATGTATGTGCCTTCACCATTGAA
GCCCACTCCTATTAATTTATCCACTTATTCTCCGCTTTCACTGAAATGCT
CATCAGCTTCAAAAGAGACAACCAATAATTCAAATTCAGAGAAATGGAAC
GAAACATCTACTTCCAATGCAATTTATCCTGCTCTTCAATTTTTATCTAA
TATATCAGTCGCATCTTCGACAACGTCATCGTGCATAACTAACATTAAAG
TTGAGAAGTCAAATAACACTCATAGTAAAAACAATAATAAAAAACAGGAC
TCACTTCATGAATTGCGATTTTGCAAATCAACTCATCACAAAGATAGTCC
AAAACCTCATATTAAAAAACCTTTAAATGCATTTATGTTGTTTATGAAAG
AAATGAGGCAGACAGTTCAAGAAGAGTGTACACTTAAAGAGTCAGCTGCT
ATCAATCAAATTCTAGGTAAAAAGTGGCATACATTAAGTCGCGAGGAACA
ATCAAAATATTATGAAATAGCGAAAAAGGAAAAGCAACTGCATATACAAT
TATTTCCTGATTGGTCAGCCAGAGATAATTATGCAATACACAGTAAGCAT
AAAAAGAAAAGGCGTATGTTTGATAATAATATCATTTATATTTATTCACT
GATTAATAATTGTTTTTCAGGGCTTAGTCAAACTGGCTACGTCGACAATA
CAGATTGTAAAAGCAATGACAACAATAATATGAAGAAATGTAGAGCGCGT
TATGGTATAGAACAAATGTCGCAGTGGTGTAAGCCATGCAGACGTAAGAA
AAAATGCATTCGATTTTTGAAAAATGATGATAATGATATGATAGCAAAAG
ATTCAAAACACATCACATTCCAGAAATCGAAAGATTCATCGATATATGAT
CTCGATTCTATTGGTGATAAAGACCCTTTTAGTGATGATAGAAAATCTTA
TAGTAGCCAAGCTCCTTCTCCTCAAGGTCCATTTTTAAGTGATAATGAGC
CTTCGGTACCACCTAATAATTGTATAAATGAAATAAACAAAACTACTTCA
TCATCACAGTCATCAATTGTTAATAAAATGAGCTGTAGTTCTTTCAAGCC
TCAAATTGAATTTGGAGGTAAAATCGAACCTACTATCAAAGGACTTGAAC
AGTCTAACAGTGCTTCCACGAATACAAATTCTGAATTTTCATCAAATATT
ATTCCCTCTCCATCTTCTGCCTTTTCTTCATTGAAGTCTTCAGTTAATCA
AGAAAAATTAAACTCCACGCAACTTATAACTATATGAAACCAGAATAGGC
ACAGTCGTTACGTAGTGGTTATAGTTGAAGAATTTTTTATATGTAGCTCT
GTTCGGTAATTTTTGAGATGAAAATTGTCTGATTTGTGAATTTCATGAGA
TCTCATTTTGGTATTAATTTAACACTGATATTTTTGTGAATGCTTATTAT
TATTATTATTATTAAAGTGTATAATAATTATTATTTATATGAATGCTAGT
ATTTGCTAGTGTCAACAACGTCTGTAATGCAACATACCTTTACACAGAAG
CCCAATGTTGATTATATATTTATTTATGTATAGGAAAGTTTTAGTTATTC
TGACAATAGATGTATGTAATCATTTTTTTTAATTGCAAATGTTATTTCTG
GTAAATTTGTATTGTTTTCAGTAATATTACTACTGAATGATTTGTACTGG
TGGTAAATTCATACAGGGTTTTTAATTTCCTTGGCTTTAAATCAGGGTAT
CCTAAAACAGAATTATATTATGACTAGTTTGACTAGTGTTATTAATTTGT
TCATTTTGTTAATATTAAATGTTGAAAATTTGGTATTGAGAATACTCATG
TCATTTTAATTCATGCAAAGTATTGCATTCACTGTATTTTTGGCATTATA
TAAATATTTGGGCTTTATTTATTAAC
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protein sequence of SMED30014712-orf-1

>SMED30014712-orf-1 ID=SMED30014712-orf-1|Name=SMED30014712-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=655bp
MAQIVNSSEECTCKDEVRVYKDEGEEEDEKNRSSENLSEDKVNLVTEGED
QKPLNFSDIFRPSYDAVFNAPFADYLFPPYPGSYAAAFSQDSSFTSKVPF
MPPNPGTFGFMPFSMRDAIESCGLNGALGFSNAYPFSSRNGFMFEHLWHS
LPPGPHISALCSENFASMWANSNSQSFSLLNPFMSSVASSTNNPVVTGSE
SSSSSIATTSTTVIASTSSNSTLTTSKDTLNSNGLMYVPSPLKPTPINLS
TYSPLSLKCSSASKETTNNSNSEKWNETSTSNAIYPALQFLSNISVASST
TSSCITNIKVEKSNNTHSKNNNKKQDSLHELRFCKSTHHKDSPKPHIKKP
LNAFMLFMKEMRQTVQEECTLKESAAINQILGKKWHTLSREEQSKYYEIA
KKEKQLHIQLFPDWSARDNYAIHSKHKKKRRMFDNNIIYIYSLINNCFSG
LSQTGYVDNTDCKSNDNNNMKKCRARYGIEQMSQWCKPCRRKKKCIRFLK
NDDNDMIAKDSKHITFQKSKDSSIYDLDSIGDKDPFSDDRKSYSSQAPSP
QGPFLSDNEPSVPPNNCINEINKTTSSSQSSIVNKMSCSSFKPQIEFGGK
IEPTIKGLEQSNSASTNTNSEFSSNIIPSPSSAFSSLKSSVNQEKLNSTQ
LITI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005667transcription factor complex
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0006357regulation of transcription from RNA polymerase II promoter
GO:0007275multicellular organism development
GO:0060070canonical Wnt signaling pathway
GO:0016055Wnt signaling pathway
Vocabulary: molecular function
TermDefinition
GO:0008013beta-catenin binding
GO:0008134transcription factor binding
GO:0003677DNA binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000044cephalic ganglia
PLANA:0000097ventral nerve cord
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR036910HMG_box_dom_sf
IPR024940TCF/LEF
IPR009071HMG_box_dom
IPR027397Catenin_binding_dom_sf
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009071High mobility group box domainSMARTSM00398hmgende2coord: 346..416
e-value: 2.0E-19
score: 80.5
IPR009071High mobility group box domainPFAMPF00505HMG_boxcoord: 347..414
e-value: 1.2E-18
score: 67.3
IPR009071High mobility group box domainPROSITEPS50118HMG_BOX_2coord: 347..415
score: 15.618
NoneNo IPR availableSMARTSM01366c_clamp_2coord: 470..500
e-value: 8.4E-15
score: 65.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 20..43
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 541..561
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 537..561
NoneNo IPR availablePANTHERPTHR10373:SF38PROTEIN PANGOLIN, ISOFORM Jcoord: 11..631
NoneNo IPR availableCDDcd01388SOX-TCF_HMG-boxcoord: 346..417
e-value: 9.53868E-35
score: 123.948
IPR036910High mobility group box domain superfamilyGENE3DG3DSA:1.10.30.10coord: 345..431
e-value: 4.3E-22
score: 80.3
IPR036910High mobility group box domain superfamilySUPERFAMILYSSF47095HMG-boxcoord: 346..425
IPR024940Transcription factor TCF/LEFPANTHERPTHR10373TRANSCRIPTION FACTOR 7 FAMILY MEMBERcoord: 11..631