Ubiquitin-conjugating enzyme E2 Z

Overview
NameUbiquitin-conjugating enzyme E2 Z
Smed IDSMED30014655
Length (bp)852
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ubiquitin-conjugating enzyme E2 Z (SMED30014655) t-SNE clustered cells

Violin plots show distribution of expression levels for Ubiquitin-conjugating enzyme E2 Z (SMED30014655) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ubiquitin-conjugating enzyme E2 Z (SMED30014655) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ubiquitin-conjugating enzyme E2 Z (SMED30014655) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014655

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30014655SMESG000055888.1 Contig953GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
parenchymal cellSMED30014655SMESG000055888.1 dd_Smed_v4_2349_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior sideSMED30014655SMESG000055888.1 dd_Smed_v4_2349_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30014655SMESG000055888.1 dd_Smed_v4_2349_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014655SMESG000055888.1 dd_Smed_v4_2349_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Human
Match: UBE2Z (ubiquitin conjugating enzyme E2 Z [Source:HGNC Symbol;Acc:HGNC:25847])

HSP 1 Score: 166.392 bits (420), Expect = 1.381e-48
Identity = 92/191 (48.17%), Postives = 123/191 (64.40%), Query Frame = 3 
Query:   69 RLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
            R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTGN TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  T+  AV  M++     P  L  + ++ F + Y  Y+  C+   +L+
Sbjct:  103 RIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQ 293
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Human
Match: UBE2Z (ubiquitin conjugating enzyme E2 Z [Source:HGNC Symbol;Acc:HGNC:25847])

HSP 1 Score: 125.561 bits (314), Expect = 6.048e-36
Identity = 58/97 (59.79%), Postives = 70/97 (72.16%), Query Frame = 3 
Query:   96 HNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSIST 386
            + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTGN TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+
Sbjct:    4 YKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISS 100
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Human
Match: BIRC6 (baculoviral IAP repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:13516])

HSP 1 Score: 103.605 bits (257), Expect = 5.006e-24
Identity = 52/103 (50.49%), Postives = 63/103 (61.17%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+S+QSL+
Sbjct: 4597 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLI 4699
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Human
Match: UBE2B (ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473])

HSP 1 Score: 90.1225 bits (222), Expect = 1.190e-21
Identity = 45/122 (36.89%), Postives = 68/122 (55.74%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N+++ +A+I GP+GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSK-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Human
Match: UBE2A (ubiquitin conjugating enzyme E2 A [Source:HGNC Symbol;Acc:HGNC:12472])

HSP 1 Score: 89.3521 bits (220), Expect = 2.273e-21
Identity = 45/122 (36.89%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N++  +A+I GP+GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSK-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Celegans
Match: ubc-17 (Probable ubiquitin-conjugating enzyme protein 17 [Source:UniProtKB/Swiss-Prot;Acc:Q11076])

HSP 1 Score: 113.62 bits (283), Expect = 5.086e-28
Identity = 58/122 (47.54%), Postives = 71/122 (58.20%), Query Frame = 3 
Query:   57 RNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTPIMSISTVLISIQSLL 413
            R  K L +  N    +  + I++ YD+  +  I  LI GP  TPY  G F F +  P  YP SPPK  F TTG+G VRFNPNLY  GK+CLSILGTW G     W P  S+  VL+SIQ L+
Sbjct:  406 RIAKELASIANALPLNASNSIYVCYDEGRVDIIKVLISGPDDTPYANGLFEFDIFFPTGYPFSPPKCAFLTTGSGNVRFNPNLYNDGKICLSILGTWEGRPEEKWNPYCSLMQVLVSIQGLI 527
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Celegans
Match: ubc-17 (Probable ubiquitin-conjugating enzyme protein 17 [Source:UniProtKB/Swiss-Prot;Acc:Q11076])

HSP 1 Score: 113.62 bits (283), Expect = 5.086e-28
Identity = 58/122 (47.54%), Postives = 71/122 (58.20%), Query Frame = 3 
Query:   57 RNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTPIMSISTVLISIQSLL 413
            R  K L +  N    +  + I++ YD+  +  I  LI GP  TPY  G F F +  P  YP SPPK  F TTG+G VRFNPNLY  GK+CLSILGTW G     W P  S+  VL+SIQ L+
Sbjct:  406 RIAKELASIANALPLNASNSIYVCYDEGRVDIIKVLISGPDDTPYANGLFEFDIFFPTGYPFSPPKCAFLTTGSGNVRFNPNLYNDGKICLSILGTWEGRPEEKWNPYCSLMQVLVSIQGLI 527
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Celegans
Match: ubc-13 (Ubiquitin-conjugating enzyme E2 13 [Source:UniProtKB/Swiss-Prot;Acc:Q95XX0])

HSP 1 Score: 86.6557 bits (213), Expect = 7.860e-21
Identity = 44/122 (36.07%), Postives = 69/122 (56.56%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            M+G+  +R+  +  +   DP  GI  + D+ N    H +I GP  +P+ GG F  ++ LP +YP + PKV F T       ++PN+ + G++CL IL       W+P + I TVL+SIQ+LL
Sbjct:    1 MAGQLPRRIIKETQRLLADPVPGISANPDESNARYFHVMIAGPDDSPFAGGVFKLELFLPEEYPMAAPKVRFMTK-----IYHPNIDKLGRICLDILKD----KWSPALQIRTVLLSIQALL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Celegans
Match: ubc-1 (Ubiquitin-conjugating enzyme E2 1 [Source:UniProtKB/Swiss-Prot;Acc:P52478])

HSP 1 Score: 86.2705 bits (212), Expect = 2.950e-20
Identity = 43/122 (35.25%), Postives = 65/122 (53.28%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            M+  + +RL  D  K   DPP G+     + N++   A+I GP+ TP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   ++ +L SIQSLL
Sbjct:    1 MTTPSRRRLMRDFKKLQEDPPAGVSGAPTEDNILTWEAIIFGPQETPFEDGTFKLSLEFTEEYPNKPPTVKFISK-----MFHPNVYADGSICLDILQN----RWSPTYDVAAILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Celegans
Match: ubc-14 (UBiquitin Conjugating enzyme [Source:UniProtKB/TrEMBL;Acc:Q9U1Q1])

HSP 1 Score: 83.1889 bits (204), Expect = 2.244e-19
Identity = 50/135 (37.04%), Postives = 70/135 (51.85%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFL-DYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPG------------WTPIMSISTVLISIQSLL 413
            M+G  +KRL  +  +    PP GI     D+ N  E   LI GP+ T +  G F  ++  P DYP SPPK+ F T G     F+PN+Y  G+VC+SIL     PG            W+P+ SI  +L+S+ S+L
Sbjct:    1 MAGYALKRLMTEYKELTTRPPEGIIAAPIDEDNFFEWECLITGPEETCFANGVFPARITFPQDYPLSPPKMRF-TCGI----FHPNIYADGRVCISIL---HAPGDDPTGYELSNERWSPVQSIEKILLSVVSML 127
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Fly
Match: Ubc7 (gene:FBgn0267384 transcript:FBtr0340157)

HSP 1 Score: 91.6633 bits (226), Expect = 1.738e-22
Identity = 49/132 (37.12%), Postives = 72/132 (54.55%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLD-YDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGT---------WSGPGWTPIMSISTVLISIQSLL 413
            M+G  ++RL A+  +   DPP GI      + N  E  ALI GP+GT +EGG F  ++  P DYP SPPK+ F         F+PN++  G+VC+SIL            S   W+P+ S+  +L+S+ S+L
Sbjct:    1 MAGSALRRLMAEYKQLTLDPPEGIVAGPISEDNFFEWEALIAGPEGTCFEGGVFPARLIFPTDYPLSPPKMKFTCD-----MFHPNIFADGRVCISILHAPGDDPMGYELSAERWSPVQSVEKILLSVVSML 127
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Fly
Match: Ubc7 (gene:FBgn0267384 transcript:FBtr0074283)

HSP 1 Score: 91.6633 bits (226), Expect = 1.738e-22
Identity = 49/132 (37.12%), Postives = 72/132 (54.55%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLD-YDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGT---------WSGPGWTPIMSISTVLISIQSLL 413
            M+G  ++RL A+  +   DPP GI      + N  E  ALI GP+GT +EGG F  ++  P DYP SPPK+ F         F+PN++  G+VC+SIL            S   W+P+ S+  +L+S+ S+L
Sbjct:    1 MAGSALRRLMAEYKQLTLDPPEGIVAGPISEDNFFEWEALIAGPEGTCFEGGVFPARLIFPTDYPLSPPKMKFTCD-----MFHPNIFADGRVCISILHAPGDDPMGYELSAERWSPVQSVEKILLSVVSML 127
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Fly
Match: CG3473 (gene:FBgn0028913 transcript:FBtr0080661)

HSP 1 Score: 86.2705 bits (212), Expect = 1.294e-20
Identity = 46/115 (40.00%), Postives = 64/115 (55.65%), Query Frame = 3 
Query:   69 RLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            R+  +  +   DP  GI    D+ N    H L+ GPK +P+EGG F  ++ LP DYP   PKV F T       F+PN+ + G++CL IL       W+P + I TVL+SIQ+LL
Sbjct:    7 RIIKETQRLLEDPVPGISATPDECNARYFHVLVTGPKDSPFEGGNFKLELFLPEDYPMKAPKVRFLTKI-----FHPNIDRVGRICLDILKD----KWSPALQIRTVLLSIQALL 112
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Fly
Match: CG3473 (gene:FBgn0028913 transcript:FBtr0343700)

HSP 1 Score: 86.2705 bits (212), Expect = 1.294e-20
Identity = 46/115 (40.00%), Postives = 64/115 (55.65%), Query Frame = 3 
Query:   69 RLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            R+  +  +   DP  GI    D+ N    H L+ GPK +P+EGG F  ++ LP DYP   PKV F T       F+PN+ + G++CL IL       W+P + I TVL+SIQ+LL
Sbjct:    7 RIIKETQRLLEDPVPGISATPDECNARYFHVLVTGPKDSPFEGGNFKLELFLPEDYPMKAPKVRFLTKI-----FHPNIDRVGRICLDILKD----KWSPALQIRTVLLSIQALL 112
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Fly
Match: Bruce (gene:FBgn0266717 transcript:FBtr0331684)

HSP 1 Score: 91.6633 bits (226), Expect = 2.537e-20
Identity = 48/103 (46.60%), Postives = 59/103 (57.28%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D   L  +  LI GP  TPY  G F F +  P DYP+ P  +  +TTG  +VRFNPNLY  GKVCLS+L TW G     W     S   VL+SIQSL+
Sbjct: 4545 VFVRCDTDRLDIMKVLITGPADTPYANGCFEFDVFFPPDYPNQPMLINLETTGRHSVRFNPNLYNDGKVCLSVLNTWHGRPEEKWNAQTSSFLQVLVSIQSLI 4647
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Zebrafish
Match: ube2z (ubiquitin-conjugating enzyme E2Z [Source:NCBI gene;Acc:436602])

HSP 1 Score: 171.014 bits (432), Expect = 2.474e-50
Identity = 95/199 (47.74%), Postives = 129/199 (64.82%), Query Frame = 3 
Query:   45 KMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
            K S + + R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTG+ TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  TM  AV  ML+     P  L+ + ++ F + Y  Y+  C++  +L+
Sbjct:  119 KASQQCILRIKRDIMSIYKEPPPGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLITTGHNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETMRVAVCDMLEGKVSCPEALWSVMEKSFLEYYDFYEGVCKERLHLQ 317
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Zebrafish
Match: ube2z (ubiquitin-conjugating enzyme E2Z [Source:NCBI gene;Acc:436602])

HSP 1 Score: 171.014 bits (432), Expect = 2.474e-50
Identity = 95/199 (47.74%), Postives = 129/199 (64.82%), Query Frame = 3 
Query:   45 KMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
            K S + + R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTG+ TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  TM  AV  ML+     P  L+ + ++ F + Y  Y+  C++  +L+
Sbjct:  119 KASQQCILRIKRDIMSIYKEPPPGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLITTGHNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETMRVAVCDMLEGKVSCPEALWSVMEKSFLEYYDFYEGVCKERLHLQ 317
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Zebrafish
Match: birc6 (baculoviral IAP repeat containing 6 [Source:ZFIN;Acc:ZDB-GENE-091202-7])

HSP 1 Score: 104.76 bits (260), Expect = 1.013e-24
Identity = 53/103 (51.46%), Postives = 64/103 (62.14%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP+SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+SIQSL+
Sbjct: 3164 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSIQSLI 3266
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Zebrafish
Match: birc6 (baculoviral IAP repeat containing 6 [Source:ZFIN;Acc:ZDB-GENE-091202-7])

HSP 1 Score: 104.76 bits (260), Expect = 1.013e-24
Identity = 53/103 (51.46%), Postives = 64/103 (62.14%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP+SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+SIQSL+
Sbjct: 4667 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSIQSLI 4769
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Zebrafish
Match: ube2g2 (ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-050417-288])

HSP 1 Score: 89.7373 bits (221), Expect = 1.227e-21
Identity = 50/135 (37.04%), Postives = 75/135 (55.56%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLD-YDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPG------------WTPIMSISTVLISIQSLL 413
            M+G  +KRL A+  +   +PP GI     +++N  E  ALI+GP+ T +EGG F   +  P+DYP SPPK+ F         F+PN+Y  G+VC+SIL     PG            W+P+ S+  +L+S+ S+L
Sbjct:    1 MAGTALKRLMAEYKQLTLNPPEGIVAGPVNEENFFEWEALIMGPEDTCFEGGVFPAILSFPSDYPLSPPKMKFTCD-----MFHPNIYPDGRVCISIL---HAPGDDPMGYESSAERWSPVQSVEKILLSVVSML 127
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Xenopus
Match: ube2z (ubiquitin conjugating enzyme E2Z [Source:NCBI gene;Acc:493338])

HSP 1 Score: 169.859 bits (429), Expect = 1.689e-50
Identity = 93/200 (46.50%), Postives = 128/200 (64.00%), Query Frame = 3 
Query:   42 SKMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
             + S + + R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTGN TVRFNPN Y+ GKVCLSILGTW+GP W+P  S+S+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  T+  AV  ML+     P+ L  + ++ F + Y  Y+  C+   +L+
Sbjct:   53 ERASNQCVLRIKRDIMSIYKEPPPGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSLSSVLISIQSLMTENPYHNEPGFEQERHSGDSKNYNECIRHETIRVAVCEMLEGKCQCPDALRSVMEKSFMEYYDFYEAVCKDRFHLQ 252
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Xenopus
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:Xenbase;Acc:XB-GENE-987109])

HSP 1 Score: 104.76 bits (260), Expect = 1.471e-24
Identity = 53/103 (51.46%), Postives = 64/103 (62.14%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP+SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+SIQSL+
Sbjct: 4579 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSIQSLI 4681
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Xenopus
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:Xenbase;Acc:XB-GENE-987109])

HSP 1 Score: 104.76 bits (260), Expect = 1.679e-24
Identity = 53/103 (51.46%), Postives = 64/103 (62.14%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP+SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+SIQSL+
Sbjct: 4550 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSIQSLI 4652
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Xenopus
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:Xenbase;Acc:XB-GENE-987109])

HSP 1 Score: 104.76 bits (260), Expect = 1.714e-24
Identity = 53/103 (51.46%), Postives = 64/103 (62.14%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP+SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+SIQSL+
Sbjct: 3244 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSIQSLI 3346
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Xenopus
Match: parp3 (poly(ADP-ribose) polymerase family member 3 [Source:Xenbase;Acc:XB-GENE-987109])

HSP 1 Score: 104.76 bits (260), Expect = 1.743e-24
Identity = 53/103 (51.46%), Postives = 64/103 (62.14%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP+SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+SIQSL+
Sbjct: 4547 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPNSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSIQSLI 4649
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Mouse
Match: Ube2z (ubiquitin-conjugating enzyme E2Z [Source:MGI Symbol;Acc:MGI:1343160])

HSP 1 Score: 166.392 bits (420), Expect = 8.478e-49
Identity = 92/191 (48.17%), Postives = 123/191 (64.40%), Query Frame = 3 
Query:   69 RLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
            R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTGN TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  T+  AV  M++     P  L  + ++ F + Y  Y+  C+   +L+
Sbjct:  105 RIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQ 295
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Mouse
Match: Birc6 (baculoviral IAP repeat-containing 6 [Source:MGI Symbol;Acc:MGI:1276108])

HSP 1 Score: 103.605 bits (257), Expect = 2.871e-24
Identity = 52/103 (50.49%), Postives = 63/103 (61.17%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+S+QSL+
Sbjct: 4593 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLI 4695
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Mouse
Match: Birc6 (baculoviral IAP repeat-containing 6 [Source:MGI Symbol;Acc:MGI:1276108])

HSP 1 Score: 103.605 bits (257), Expect = 2.871e-24
Identity = 52/103 (50.49%), Postives = 63/103 (61.17%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+S+QSL+
Sbjct: 4607 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLI 4709
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Mouse
Match: Birc6 (baculoviral IAP repeat-containing 6 [Source:MGI Symbol;Acc:MGI:1276108])

HSP 1 Score: 103.605 bits (257), Expect = 2.871e-24
Identity = 52/103 (50.49%), Postives = 63/103 (61.17%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+S+QSL+
Sbjct: 4609 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLI 4711
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Mouse
Match: Birc6 (baculoviral IAP repeat-containing 6 [Source:MGI Symbol;Acc:MGI:1276108])

HSP 1 Score: 103.605 bits (257), Expect = 2.872e-24
Identity = 52/103 (50.49%), Postives = 63/103 (61.17%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGWTP-IMSISTVLISIQSLL 413
            +F+  D++ L  +  LI GP  TPY  G F F +  P DYP SPP V  +TTG  +VRFNPNLY  GKVCLSIL TW G     W P   S   VL+S+QSL+
Sbjct: 4613 VFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLI 4715
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. UniProt/SwissProt
Match: sp|Q6DG60|UBE2Z_DANRE (Ubiquitin-conjugating enzyme E2 Z OS=Danio rerio OX=7955 GN=ube2z PE=2 SV=2)

HSP 1 Score: 171.4 bits (433), Expect = 3.109e-50
Identity = 95/200 (47.50%), Postives = 129/200 (64.50%), Query Frame = 3 
Query:   42 SKMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
             K S + + R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTG+ TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  TM  AV  ML+     P  L+ + ++ F + Y  Y+  C++  +L+
Sbjct:   66 EKASQQCILRIKRDIMSIYKEPPPGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLITTGHNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETMRVAVCDMLEGKVSCPEALWSVMEKSFLEYYDFYEGVCKERLHLQ 265
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. UniProt/SwissProt
Match: sp|Q66KB0|UBE2Z_XENTR (Ubiquitin-conjugating enzyme E2 Z OS=Xenopus tropicalis OX=8364 GN=ube2z PE=2 SV=2)

HSP 1 Score: 169.859 bits (429), Expect = 8.949e-50
Identity = 93/200 (46.50%), Postives = 128/200 (64.00%), Query Frame = 3 
Query:   42 SKMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
             + S + + R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTGN TVRFNPN Y+ GKVCLSILGTW+GP W+P  S+S+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  T+  AV  ML+     P+ L  + ++ F + Y  Y+  C+   +L+
Sbjct:   53 ERASNQCVLRIKRDIMSIYKEPPPGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSLSSVLISIQSLMTENPYHNEPGFEQERHSGDSKNYNECIRHETIRVAVCEMLEGKCQCPDALRSVMEKSFMEYYDFYEAVCKDRFHLQ 252
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. UniProt/SwissProt
Match: sp|Q6PCF7|UBE2Z_XENLA (Ubiquitin-conjugating enzyme E2 Z OS=Xenopus laevis OX=8355 GN=ube2z PE=2 SV=2)

HSP 1 Score: 169.859 bits (429), Expect = 1.018e-49
Identity = 93/200 (46.50%), Postives = 128/200 (64.00%), Query Frame = 3 
Query:   42 SKMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
             + S + + R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTGN TVRFNPN Y+ GKVCLSILGTW+GP W+P  S+S+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  T+  AV  ML+     P+ L  + ++ F + Y  Y+  C+   +L+
Sbjct:   53 ERASTQCVLRIKRDIMSIYKEPPPGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSLSSVLISIQSLMTENPYHNEPGFEQERHSGDSKNYNECIRHETIRVAVCEMLEGKCQCPDALRSVMEKSFMEYYDFYEAVCKDRFHLQ 252
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. UniProt/SwissProt
Match: sp|Q3UE37|UBE2Z_MOUSE (Ubiquitin-conjugating enzyme E2 Z OS=Mus musculus OX=10090 GN=Ube2z PE=1 SV=2)

HSP 1 Score: 166.392 bits (420), Expect = 5.930e-48
Identity = 92/191 (48.17%), Postives = 123/191 (64.40%), Query Frame = 3 
Query:   69 RLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
            R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTGN TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  T+  AV  M++     P  L  + ++ F + Y  Y+  C+   +L+
Sbjct:  105 RIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQ 295
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. UniProt/SwissProt
Match: sp|Q9H832|UBE2Z_HUMAN (Ubiquitin-conjugating enzyme E2 Z OS=Homo sapiens OX=9606 GN=UBE2Z PE=1 SV=2)

HSP 1 Score: 166.392 bits (420), Expect = 6.633e-48
Identity = 92/191 (48.17%), Postives = 123/191 (64.40%), Query Frame = 3 
Query:   69 RLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
            R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTGN TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  T+  AV  M++     P  L  + ++ F + Y  Y+  C+   +L+
Sbjct:  103 RIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQ 293
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. TrEMBL
Match: A0A0B7A662 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Arion vulgaris OX=1028688 GN=ORF95801 PE=4 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 5.828e-52
Identity = 97/192 (50.52%), Postives = 133/192 (69.27%), Query Frame = 3 
Query:   63 MKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYL 638
            ++R+  DI   ++DPP G+ +  D  N+ +IHAL+ GP  TPYEGGFFYF +  PADYP SPP+V   TTGNGTVRFNPNLY+ GKVCLSILGTW+GP W+P  ++STVLISIQSL+NE+PY+NEPG+++ +    S  YN  ++  T+  AV  M++ +  +P+ L  + +  F D Y  Y + C+   YL
Sbjct:   77 IRRIKNDILAIYSDPPPGLCVMPDPNNITKIHALLTGPFDTPYEGGFFYFLIRFPADYPISPPRVRLMTTGNGTVRFNPNLYKNGKVCLSILGTWAGPSWSPAQTLSTVLISIQSLMNEKPYHNEPGFKHERTSGDSKHYNDIIQHETLRVAVCDMIEGNIRIPDTLRAVMESSFPDYYKYYIQVCENLQYL 268
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. TrEMBL
Match: A0A0B7A3L2 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Arion vulgaris OX=1028688 GN=ORF95816 PE=4 SV=1)

HSP 1 Score: 182.57 bits (462), Expect = 6.640e-52
Identity = 97/192 (50.52%), Postives = 133/192 (69.27%), Query Frame = 3 
Query:   63 MKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYL 638
            ++R+  DI   ++DPP G+ +  D  N+ +IHAL+ GP  TPYEGGFFYF +  PADYP SPP+V   TTGNGTVRFNPNLY+ GKVCLSILGTW+GP W+P  ++STVLISIQSL+NE+PY+NEPG+++ +    S  YN  ++  T+  AV  M++ +  +P+ L  + +  F D Y  Y + C+   YL
Sbjct:   86 IRRIKNDILAIYSDPPPGLCVMPDPNNITKIHALLTGPFDTPYEGGFFYFLIRFPADYPISPPRVRLMTTGNGTVRFNPNLYKNGKVCLSILGTWAGPSWSPAQTLSTVLISIQSLMNEKPYHNEPGFKHERTSGDSKHYNDIIQHETLRVAVCDMIEGNIRIPDTLRAVMESSFPDYYKYYIQVCENLQYL 277
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. TrEMBL
Match: A0A0P4VIN3 (Putative inhibitor of apoptosis 1 (Fragment) OS=Rhodnius neglectus OX=72488 PE=2 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 1.408e-51
Identity = 101/194 (52.06%), Postives = 129/194 (66.49%), Query Frame = 3 
Query:   63 MKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKH--TVMPNKLYLIAKQYFQDNYSTYKETCQKFSYL 638
            + R+  D+   ++DPP GIF+  D+++L  IHALI G   TPYEGGFFYF +  P DYP  PPKV F TTG G VRFNPNLY+CGKVC+SILGTW+GP W+P ++IS+VLISIQSLL E+PY+NEPG+E  +    S  YN+ ++  T+  AV GMLD      +P  L     Q F   Y  Y+ T QK  +L
Sbjct:   16 ISRVKRDMLAIYHDPPPGIFIIQDEQDLTLIHALITGSFDTPYEGGFFYFILRCPPDYPIRPPKVKFMTTGGGKVRFNPNLYKCGKVCISILGTWAGPAWSPALTISSVLISIQSLLTEKPYHNEPGFERERCMGDSRRYNEIIQHETIRVAVCGMLDNDYGLTIPKPLVEAMNQAFLQFYEYYEATIQKKIHL 209
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. TrEMBL
Match: T1HEX4 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Rhodnius prolixus OX=13249 PE=4 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 3.699e-51
Identity = 101/194 (52.06%), Postives = 129/194 (66.49%), Query Frame = 3 
Query:   63 MKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKH--TVMPNKLYLIAKQYFQDNYSTYKETCQKFSYL 638
            + R+  D+   ++DPP GIF+  D+++L  IHALI G   TPYEGGFFYF +  P DYP  PPKV F TTG G VRFNPNLY+CGKVC+SILGTW+GP W+P ++IS+VLISIQSLL E+PY+NEPG+E  +    S  YN+ ++  T+  AV GMLD      +P  L     Q F   Y  Y+ T QK  +L
Sbjct:   48 ISRVKRDMLAIYHDPPPGIFIIQDEQDLTLIHALITGSFDTPYEGGFFYFILRCPPDYPIRPPKVKFMTTGGGKVRFNPNLYKCGKVCISILGTWAGPAWSPALTISSVLISIQSLLTEKPYHNEPGFERERCMGDSRRYNEIIQHETIRVAVCGMLDNDYGLTIPKPLVEAMNQAFLQFYEYYEATIQKKIHL 241
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. TrEMBL
Match: A0A1I8IIU7 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009681g1 PE=4 SV=1)

HSP 1 Score: 177.563 bits (449), Expect = 1.361e-50
Identity = 94/189 (49.74%), Postives = 126/189 (66.67%), Query Frame = 3 
Query:   63 MKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTV-MPNKLYLIAKQYFQDNYSTYKETCQK 626
            + R+  ++    NDP  GIF+  DD +L ++HAL+ GP  TPYEGGFFY  M +P  YP+ PP+    TTGNG VRFNPNLY+ GK+CLSILGTW GPGWTP+MS+ +VL+SIQ+LLNE PY+NEPG+E  + Q  + AYN  +   T+  AV  ML++    +P   Y + +  F D Y  Y E C++
Sbjct:   42 LARVKNELVSIFNDPIPGIFVVQDDADLGKVHALLTGPFETPYEGGFFYIIMRVPPQYPNQPPRARLVTTGNGQVRFNPNLYKNGKICLSILGTWQGPGWTPVMSLRSVLLSIQTLLNERPYHNEPGFEVERQQGDAQAYNDIITHETIRAAVCDMLERRVSNLPKPFYQVMQDNFPDYYQHYTEICRR 230
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Cavefish
Match: ube2z (ubiquitin conjugating enzyme E2 Z [Source:NCBI gene;Acc:103043332])

HSP 1 Score: 170.629 bits (431), Expect = 4.303e-50
Identity = 95/199 (47.74%), Postives = 129/199 (64.82%), Query Frame = 3 
Query:   45 KMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
            K S + + R+  DI   + +PP G+F+  D  ++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTG+ TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  TM  AV  ML+     P  L+ + ++ F + Y  Y+  C++  +L+
Sbjct:  138 KASQQCILRIKRDIMSIYKEPPPGMFVVPDPHDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLITTGHNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETMRVAVCDMLEGKVPCPEALWSVMEKSFLEYYDFYEGVCKERLHLQ 336
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Cavefish
Match: ube2g2 (ubiquitin conjugating enzyme E2 G2 [Source:NCBI gene;Acc:103032398])

HSP 1 Score: 90.1225 bits (222), Expect = 7.850e-22
Identity = 50/135 (37.04%), Postives = 75/135 (55.56%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLD-YDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPG------------WTPIMSISTVLISIQSLL 413
            M+G  +KRL A+  +   +PP GI     +++N  E  ALI+GP+ T +EGG F   +  P+DYP SPPK+ F         F+PN+Y  G+VC+SIL     PG            W+P+ S+  +L+S+ S+L
Sbjct:    1 MAGTALKRLMAEYKQLTLNPPEGIVAGPVNEENFFEWEALIMGPEDTCFEGGVFPAVLSFPSDYPLSPPKMKFTCD-----MFHPNIYPDGRVCISIL---HAPGDDPMGYESSAERWSPVQSVEKILLSVVSML 127
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Cavefish
Match: ube2a (ubiquitin conjugating enzyme E2 A [Source:NCBI gene;Acc:103035357])

HSP 1 Score: 89.3521 bits (220), Expect = 1.225e-21
Identity = 45/122 (36.89%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N++  +A+I GP+GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSK-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Cavefish
Match: ENSAMXT00000050020.1 (ubiquitin-conjugating enzyme E2 A-like [Source:NCBI gene;Acc:103029486])

HSP 1 Score: 89.3521 bits (220), Expect = 1.277e-21
Identity = 45/122 (36.89%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N++  +A+I GP+GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTVEFTEEYPNKPPTVRFISK-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Cavefish
Match: ube2al (ubiquitin-conjugating enzyme E2 A-like [Source:NCBI gene;Acc:103021436])

HSP 1 Score: 88.9669 bits (219), Expect = 1.463e-21
Identity = 45/122 (36.89%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N++  +A+I GP+GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMIWNAVIFGPEGTPFEDGTFKLTVEFTEEYPNKPPTVRFVSK-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Sea Lamprey
Match: ube2z (ubiquitin-conjugating enzyme E2Z [Source:NCBI gene;Acc:436602])

HSP 1 Score: 149.443 bits (376), Expect = 1.674e-44
Identity = 83/159 (52.20%), Postives = 108/159 (67.92%), Query Frame = 3 
Query:  150 EIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQK 626
            +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTG+ TVRFNPN Y+ GKVCLSILGTWSGP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ ++  T+  AV  ML+   + P+ L  + ++ F + Y  Y+  C++
Sbjct:    1 QIHALITGP-FTPYEGGFFLFLFRCPPDYPIKPPRVKLLTTGSNTVRFNPNFYRNGKVCLSILGTWSGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHSGDSKRYNECIQHETIRVAVCDMLEGRCLCPDALRSVMEKSFLEYYEFYETVCKE 158
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Sea Lamprey
Match: ube2t (ubiquitin-conjugating enzyme E2T (putative) [Source:NCBI gene;Acc:768152])

HSP 1 Score: 89.7373 bits (221), Expect = 1.563e-22
Identity = 44/119 (36.97%), Postives = 68/119 (57.14%), Query Frame = 3 
Query:   57 RNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            + + RL  ++ +  ++PP G+     D+   E+ A I+G  GTPYEGG F  ++ +P  YP  PPKVTF T       ++PN+   G++CL IL       W P +++STVL S+Q L+
Sbjct:    2 QRVSRLAREVERLASEPPPGVSCWLCDEASGELRAQILGGAGTPYEGGIFSLEVQIPDRYPFEPPKVTFLTP-----IYHPNIDTAGRICLDILKMPPKGAWRPSLNVSTVLTSVQQLM 115
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008817.1 (pep scaffold:Pmarinus_7.0:GL476329:1748443:1760143:-1 gene:ENSPMAG00000007968.1 transcript:ENSPMAT00000008817.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 89.7373 bits (221), Expect = 1.895e-22
Identity = 45/122 (36.89%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N++  +A+I GP+GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMLWNAVIFGPEGTPFEDGTFKLTLEFTEEYPNKPPTVKFVSK-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Sea Lamprey
Match: UBE2O (ubiquitin conjugating enzyme E2 O [Source:HGNC Symbol;Acc:HGNC:29554])

HSP 1 Score: 95.5153 bits (236), Expect = 2.528e-22
Identity = 50/105 (47.62%), Postives = 62/105 (59.05%), Query Frame = 3 
Query:  108 PHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPG---WTPIMSISTVLISIQSLL 413
            P GI +   +  +    ALI GP  TPYE G F F + LPA YP  PP   + +  +G  R NPNLY+ GKVC+S+LGTW G G   WT   S+  VLISIQ L+
Sbjct:  849 PEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSG--RLNPNLYENGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLI 951
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Sea Lamprey
Match: UBE2O (ubiquitin conjugating enzyme E2 O [Source:HGNC Symbol;Acc:HGNC:29554])

HSP 1 Score: 95.5153 bits (236), Expect = 2.542e-22
Identity = 50/105 (47.62%), Postives = 62/105 (59.05%), Query Frame = 3 
Query:  108 PHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPG---WTPIMSISTVLISIQSLL 413
            P GI +   +  +    ALI GP  TPYE G F F + LPA YP  PP   + +  +G  R NPNLY+ GKVC+S+LGTW G G   WT   S+  VLISIQ L+
Sbjct:  875 PEGIVVKTFEDRMDLFSALIHGPARTPYEDGLFVFDIQLPAIYPACPPSFHYLSQCSG--RLNPNLYENGKVCVSLLGTWVGKGTEKWTNKSSLLQVLISIQGLI 977
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Yeast
Match: UBC13 (E2 ubiquitin-conjugating enzyme; involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus [Source:SGD;Acc:S000002499])

HSP 1 Score: 85.8853 bits (211), Expect = 3.302e-21
Identity = 46/116 (39.66%), Postives = 65/116 (56.03%), Query Frame = 3 
Query:   66 KRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            KR+  +  K  +DP  GI  +  D NL      I GP+ +PYE G F  ++ LP DYP   PKV F T       ++PN+ + G++CL +L T     W+P + I TVL+SIQ+LL
Sbjct:    6 KRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEGPEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKI-----YHPNIDRLGRICLDVLKT----NWSPALQIRTVLLSIQALL 112
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Yeast
Match: RAD6 (Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, ERAD with Ubr1p in the absence of canonical ER membrane ligases, and Rpn4p turnover as part of proteasome homeostasis, in complex with Ubr2p and Mub1p [Source:SGD;Acc:S000003026])

HSP 1 Score: 82.4185 bits (202), Expect = 1.045e-19
Identity = 44/122 (36.07%), Postives = 64/122 (52.46%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   D P G+       N++  +A+IIGP  TPYE G F   ++   +YP+ PP V F +       F+PN+Y  G++CL IL       WTP   ++++L SIQSL 
Sbjct:    1 MSTPARRRLMRDFKRMKEDAPPGVSASPLPDNVMVWNAMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSE-----MFHPNVYANGEICLDILQN----RWTPTYDVASILTSIQSLF 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Yeast
Match: UBC7 (Ubiquitin conjugating enzyme; involved in the ER-associated protein degradation (ERAD) pathway and in the inner nuclear membrane-associated degradation (INMAD) pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly [Source:SGD;Acc:S000004624])

HSP 1 Score: 80.4925 bits (197), Expect = 4.812e-19
Identity = 50/135 (37.04%), Postives = 70/135 (51.85%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEI-HALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPG------------WTPIMSISTVLISIQSLL 413
            MS    KRL  ++ +   D P GI      +N I I   LI GP  TPY  G F  K++ P DYP SPPK+TF  +       +PN+Y  G+VC+SIL +   PG            W+P+ S+  +L+S+ S+L
Sbjct:    1 MSKTAQKRLLKELQQLIKDSPPGIVAGPKSENNIFIWDCLIQGPPDTPYADGVFNAKLEFPKDYPLSPPKLTFTPS-----ILHPNIYPNGEVCISILHS---PGDDPNMYELAEERWSPVQSVEKILLSVMSML 127
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Yeast
Match: UBC5 (Ubiquitin-conjugating enzyme; mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible; protein abundance increases in response to DNA replication stress; UBC5 has a paralog, UBC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002466])

HSP 1 Score: 78.1814 bits (191), Expect = 1.893e-18
Identity = 42/116 (36.21%), Postives = 60/116 (51.72%), Query Frame = 3 
Query:   66 KRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            KR+  +++    DPP          +L    A I+GP  +PY GG F+  +  P DYP  PPKV F T       ++PN+   G +CL IL       W+P +++S VL+SI SLL
Sbjct:    5 KRIAKELSDLGRDPPASCSAGPVGDDLYHWQASIMGPSDSPYAGGVFFLSIHFPTDYPFKPPKVNFTTK-----IYHPNINSSGNICLDILKD----QWSPALTLSKVLLSICSLL 111
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Yeast
Match: UBC1 (Ubiquitin-conjugating enzyme; key E2 partner with Ubc4p for the anaphase-promoting complex (APC); mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response; protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC) [Source:SGD;Acc:S000002584])

HSP 1 Score: 79.337 bits (194), Expect = 3.219e-18
Identity = 40/118 (33.90%), Postives = 67/118 (56.78%), Query Frame = 3 
Query:   66 KRLTADINKFHNDPPHGIFLDY-DDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQC-GKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            KR+  +I    +DP   I L++  + ++  +    +GP GTPYEGG F   +++P +YP  PPK+ F T       ++PN+    G +CL IL       W+P++++ + LIS+Q+LL
Sbjct:    5 KRIMKEIQAVKDDPAAHITLEFVSESDIHHLKGTFLGPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTK-----VYHPNISSVTGAICLDILKN----AWSPVITLKSALISLQALL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Nematostella
Match: EDO49586 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGR4])

HSP 1 Score: 154.451 bits (389), Expect = 1.444e-45
Identity = 89/169 (52.66%), Postives = 111/169 (65.68%), Query Frame = 3 
Query:  132 DDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYL 638
            D K    IHALI GP  TPYEGGFFYF +  P DYP  PP+V   TTG+G VRFNPNLY+ GKVCLSI+GTWSGP W+P  S+S+VLISIQSLLNE+PY+NEPG+E  +       YN+ ++  T+  AV  ML+     PN L  + ++ F + Y  Y     + SYL
Sbjct:   54 DFKEFSPIHALITGPFDTPYEGGFFYFLIRCPPDYPIRPPRVKLMTTGSGQVRFNPNLYRNGKVCLSIIGTWSGPAWSPAQSLSSVLISIQSLLNEKPYHNEPGFEQERQAGDCKRYNECIQHETLRVAVCDMLEGKIKCPNALKDVMEKSFPEFYDYYISVITEKSYL 222
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Nematostella
Match: EDO41556 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3W2])

HSP 1 Score: 100.908 bits (250), Expect = 2.039e-26
Identity = 61/149 (40.94%), Postives = 77/149 (51.68%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG----PGWTP-IMSISTVLISIQSLLXXX-----XXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGML 533
            I    D+  +    AL+ GP  TPY  G F F +  P  YP+ PP V   TTGNGTVRFNPNLY  GKVCLS+LGTW G      W P   S+  VL+SIQ ++            E      + +  S  YN  +R+ T+ HA+ G L
Sbjct:    5 ILFSQDENRMDFARALVTGPVDTPYSRGCFVFDIFFPGTYPNVPPLVKLITTGNGTVRFNPNLYADGKVCLSLLGTWYGGVASEKWDPKKSSLYQVLLSIQGMILIPDPCFNEPGYEGIRNTDEGEILSREYNAAIRLATVRHAMTGQL 153
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Nematostella
Match: EDO27608 (pep supercontig:ASM20922v1:NEMVEscaffold_3528:46:2297:-1 gene:NEMVEDRAFT_v1g150523 transcript:EDO27608 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 95.9005 bits (237), Expect = 2.911e-24
Identity = 51/106 (48.11%), Postives = 68/106 (64.15%), Query Frame = 3 
Query:  108 PHGIFL-DYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPG---WTPIMSISTVLISIQSLL 413
            P GI +  Y+D+  I    +I GP GTPY+ G F F + LPA+YP +PP   + +  NG  R NPNLY+ GKVC+S+LGTW+G G   WT   +I  VLIS+Q L+
Sbjct:   13 PEGILVRGYEDRMDI-FRVMIEGPAGTPYDHGLFAFDILLPANYPDAPPSFHYLSMCNG--RLNPNLYEDGKVCVSLLGTWTGRGSEIWTSKSNILQVLISVQGLI 115
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Nematostella
Match: EDO48919 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHV4])

HSP 1 Score: 94.7449 bits (234), Expect = 5.579e-24
Identity = 52/135 (38.52%), Postives = 75/135 (55.56%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLD-YDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPG------------WTPIMSISTVLISIQSLL 413
            M+G  +KRL A+  +   +PP GI      ++N  E  ALI GP+GTP+EGG F  ++  P DYP SPPK+ F         F+PN+Y  G+VC+SIL     PG            W+P+ S+  +L+S+ S+L
Sbjct:    1 MAGAALKRLMAEYKQLTVNPPEGIIAGPLTEENFFEWEALISGPEGTPFEGGVFTTRLVFPPDYPLSPPKMRFVGE-----MFHPNVYPDGRVCISIL---HAPGDDPMGYESSAERWSPVQSVEKILLSVISML 127
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Nematostella
Match: EDO28085 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7G6])

HSP 1 Score: 95.1301 bits (235), Expect = 1.292e-23
Identity = 59/150 (39.33%), Postives = 75/150 (50.00%), Query Frame = 3 
Query:  117 IFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSG---PGW-TPIMSISTVLISIQSLLXXX-----XXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDK 539
            +F+  D+  L  +  LI GP  TPY  G F F +  P +YP +P ++ F+TTG+ TVRFNPNLY  GKVCLSIL TW G     W     S   VL+S QSL+            E        Q  S  YN N+R   +  A+   L K
Sbjct:   62 VFVRCDEDRLDVMKVLITGPAETPYANGCFEFDVYFPQNYPEAPMQINFETTGHHTVRFNPNLYNDGKVCLSILNTWHGRPEEKWNAQTSSFLQVLVSTQSLILVAEPYFNEPGYERSRGTPSGQQNSQEYNANIRQACVRWAMLEQLRK 211
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Medaka
Match: ube2z (ubiquitin conjugating enzyme E2 Z [Source:NCBI gene;Acc:101168788])

HSP 1 Score: 172.17 bits (435), Expect = 1.227e-50
Identity = 95/199 (47.74%), Postives = 130/199 (65.33%), Query Frame = 3 
Query:   45 KMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLR 641
            K S + + R+  DI   + +PP G+F+  D +++ +IHALI GP  TPYEGGFF F    P DYP  PP+V   TTG+ TVRFNPN Y+ GKVCLSILGTW+GP W+P  SIS+VLISIQSL+ E PY+NEPG+E  ++   S  YN+ +R  TM  AV  ML+     P+ L+ + ++ F + Y  Y+  C+   +L+
Sbjct:  139 KASQQCILRIKRDIMSIYKEPPPGMFVVPDPQDMTKIHALITGPFDTPYEGGFFLFLFRCPPDYPIHPPRVKLITTGHNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETMRVAVCDMLEGKVPCPDALWSVMEKSFLEYYDFYEGVCKDRLHLQ 337
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Medaka
Match: ube2a (ubiquitin conjugating enzyme E2 A [Source:NCBI gene;Acc:101158032])

HSP 1 Score: 89.3521 bits (220), Expect = 1.218e-21
Identity = 45/122 (36.89%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N++  +A+I GP+GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSK-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Medaka
Match: ube2al (ubiquitin-conjugating enzyme E2 A [Source:NCBI gene;Acc:101155732])

HSP 1 Score: 88.5817 bits (218), Expect = 2.051e-21
Identity = 45/122 (36.89%), Postives = 67/122 (54.92%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N++  +A+I GP+GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLIVEFTEEYPNKPPTVRFVSK-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Medaka
Match: ube2g2 (ubiquitin conjugating enzyme E2 G2 [Source:NCBI gene;Acc:101158984])

HSP 1 Score: 90.5077 bits (223), Expect = 7.450e-21
Identity = 49/132 (37.12%), Postives = 74/132 (56.06%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLD-YDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGT---------WSGPGWTPIMSISTVLISIQSLL 413
            M+G  +KRL A+  +   +PP GI     +++N  E  ALI+GP+ T +EGG F   +  P+DYP SPPK+ F         F+PN+Y  G+VC+SIL            S   W+P+ S+  +L+S+ S+L
Sbjct:  122 MAGTALKRLMAEYKQLTLNPPEGIVAGPANEENFFEWEALIMGPEDTCFEGGVFPAVLSFPSDYPLSPPKMRFTCD-----MFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSML 248
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Medaka
Match: ube2b (ubiquitin conjugating enzyme E2 B [Source:NCBI gene;Acc:101172675])

HSP 1 Score: 87.0409 bits (214), Expect = 9.387e-21
Identity = 45/122 (36.89%), Postives = 66/122 (54.10%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLL 413
            MS    +RL  D  +   DPP G+     + N++  +A+I GP GTP+E G F   ++   +YP+ PP V F +       F+PN+Y  G +CL IL       W+P   +S++L SIQSLL
Sbjct:    1 MSTPARRRLMRDFKRLQEDPPTGVSGAPSENNIMLWNAVIFGPVGTPFEDGTFKLLIEFSEEYPNKPPTVRFVSR-----MFHPNVYADGSICLDILQN----RWSPTYDVSSILTSIQSLL 113
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Planmine SMEST
Match: SMESG000055888.1 (SMESG000055888.1)

HSP 1 Score: 393.275 bits (1009), Expect = 4.154e-140
Identity = 202/202 (100.00%), Postives = 202/202 (100.00%), Query Frame = 3 
Query:   48 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLRSAIK 653
            MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLNEEPYYNEPGYENSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLRSAIK
Sbjct:    1 MSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLNEEPYYNEPGYENSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQKFSYLRSAIK 202
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Planmine SMEST
Match: SMESG000032815.1 (SMESG000032815.1)

HSP 1 Score: 173.326 bits (438), Expect = 1.676e-52
Identity = 98/186 (52.69%), Postives = 122/186 (65.59%), Query Frame = 3 
Query:   69 RLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQK 626
            R+  D++  + DP  GIF+  D++NL  IHALI GP  TPYEGGFFYF +   ADYP  PPKV  KTTG GTVRFNPN Y+ GKVCLSILGTWSGP WTP  ++S+VLISIQSLLN++PY+NEPGY        SD YN  ++  T+  AV  +++    +P+    I +  F D Y  Y   C K
Sbjct:   38 RIKNDLSNIYKDPVPGIFVLPDNRNLSWIHALITGPFETPYEGGFFYFLIGCTADYPLKPPKVKLKTTGFGTVRFNPNFYKNGKVCLSILGTWSGPEWTPAQNLSSVLISIQSLLNDKPYFNEPGYSQESRPGDSDRYNNIIQHETIRCAVCEVMEDKMQLPDDFKAIVESTFPDYYDYYVSVCNK 223
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Planmine SMEST
Match: SMESG000013882.1 (SMESG000013882.1)

HSP 1 Score: 168.703 bits (426), Expect = 4.488e-51
Identity = 92/194 (47.42%), Postives = 128/194 (65.98%), Query Frame = 3 
Query:   42 SKMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETCQ 623
            S +S  ++ R+  ++N    DP  GI +  DDK++  IHALIIGPK TPYE GFFYF +   +DYP  PPK+  KTTG+GTVRFNPN Y+ GKVCLSI+GTWSGP WTP +++S++L+SIQSL N +PY+NEPG+    +   S+ YN  ++  T+  AV  +L+  T +P  +    ++ F   Y  Y +TC 
Sbjct:   10 SNISSSSVIRIKNELNNIARDPVPGILVLPDDKSISRIHALIIGPKDTPYENGFFYFLIGCSSDYPIKPPKIKLKTTGSGTVRFNPNFYKNGKVCLSIIGTWSGPEWTPALTLSSILLSIQSLFNNQPYFNEPGFVKESHPGVSNHYNDIIQHETIRCAVCDVLEGKTQLPADIKSYIEKSFPSYYDYYSKTCD 203
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Planmine SMEST
Match: SMESG000013882.1 (SMESG000013882.1)

HSP 1 Score: 168.703 bits (426), Expect = 5.761e-51
Identity = 92/193 (47.67%), Postives = 128/193 (66.32%), Query Frame = 3 
Query:   42 SKMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYSTYKETC 620
            S +S  ++ R+  ++N    DP  GI +  DDK++  IHALIIGPK TPYE GFFYF +   +DYP  PPK+  KTTG+GTVRFNPN Y+ GKVCLSI+GTWSGP WTP +++S++L+SIQSL N +PY+NEPG+    +   S+ YN  ++  T+  AV  +L+  T +P  +    ++ F   Y  Y +TC
Sbjct:   20 SNISSSSVIRIKNELNNIARDPVPGILVLPDDKSISRIHALIIGPKDTPYENGFFYFLIGCSSDYPIKPPKIKLKTTGSGTVRFNPNFYKNGKVCLSIIGTWSGPEWTPALTLSSILLSIQSLFNNQPYFNEPGFVKESHPGVSNHYNDIIQHETIRCAVCDVLEGKTQLPADIKSYIEKSFPSYYDYYSKTC 212
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Planmine SMEST
Match: SMESG000032815.1 (SMESG000032815.1)

HSP 1 Score: 156.377 bits (394), Expect = 5.782e-47
Identity = 88/147 (59.86%), Postives = 106/147 (72.11%), Query Frame = 3 
Query:   69 RLTADINKFHNDPPHGIFLDYDDKNLIEIHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPNLYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLXXXXXXXXXXXXXSKNQTQSDAYNQNVRMNTM 509
            R+  D++  + DP  GIF+  D++NL  IHALI GP  TPYEGGFFYF +   ADYP  PPKV  KTTG GTVRFNPN Y+ GKVCLSILGTWSGP WTP  ++S+VLISIQSLLN++PY+NEPGY        SD YN  ++  T+
Sbjct:   38 RIKNDLSNIYKDPVPGIFVLPDNRNLSWIHALITGPFETPYEGGFFYFLIGCTADYPLKPPKVKLKTTGFGTVRFNPNFYKNGKVCLSILGTWSGPEWTPAQNLSSVLISIQSLLNDKPYFNEPGYSQESRPGDSDRYNNIIQHETI 184
The following BLAST results are available for this feature:
BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
UBE2Z1.381e-4848.17ubiquitin conjugating enzyme E2 Z [Source:HGNC Sym... [more]
UBE2Z6.048e-3659.79ubiquitin conjugating enzyme E2 Z [Source:HGNC Sym... [more]
BIRC65.006e-2450.49baculoviral IAP repeat containing 6 [Source:HGNC S... [more]
UBE2B1.190e-2136.89ubiquitin conjugating enzyme E2 B [Source:HGNC Sym... [more]
UBE2A2.273e-2136.89ubiquitin conjugating enzyme E2 A [Source:HGNC Sym... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ubc-175.086e-2847.54Probable ubiquitin-conjugating enzyme protein 17 ... [more]
ubc-175.086e-2847.54Probable ubiquitin-conjugating enzyme protein 17 ... [more]
ubc-137.860e-2136.07Ubiquitin-conjugating enzyme E2 13 [Source:UniPro... [more]
ubc-12.950e-2035.25Ubiquitin-conjugating enzyme E2 1 [Source:UniProt... [more]
ubc-142.244e-1937.04UBiquitin Conjugating enzyme [Source:UniProtKB/Tr... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ubc71.738e-2237.12gene:FBgn0267384 transcript:FBtr0340157[more]
Ubc71.738e-2237.12gene:FBgn0267384 transcript:FBtr0074283[more]
CG34731.294e-2040.00gene:FBgn0028913 transcript:FBtr0080661[more]
CG34731.294e-2040.00gene:FBgn0028913 transcript:FBtr0343700[more]
Bruce2.537e-2046.60gene:FBgn0266717 transcript:FBtr0331684[more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2z2.474e-5047.74ubiquitin-conjugating enzyme E2Z [Source:NCBI gene... [more]
ube2z2.474e-5047.74ubiquitin-conjugating enzyme E2Z [Source:NCBI gene... [more]
birc61.013e-2451.46baculoviral IAP repeat containing 6 [Source:ZFIN;A... [more]
birc61.013e-2451.46baculoviral IAP repeat containing 6 [Source:ZFIN;A... [more]
ube2g21.227e-2137.04ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, ... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2z1.689e-5046.50ubiquitin conjugating enzyme E2Z [Source:NCBI gene... [more]
parp31.471e-2451.46poly(ADP-ribose) polymerase family member 3 [Sourc... [more]
parp31.679e-2451.46poly(ADP-ribose) polymerase family member 3 [Sourc... [more]
parp31.714e-2451.46poly(ADP-ribose) polymerase family member 3 [Sourc... [more]
parp31.743e-2451.46poly(ADP-ribose) polymerase family member 3 [Sourc... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ube2z8.478e-4948.17ubiquitin-conjugating enzyme E2Z [Source:MGI Symbo... [more]
Birc62.871e-2450.49baculoviral IAP repeat-containing 6 [Source:MGI Sy... [more]
Birc62.871e-2450.49baculoviral IAP repeat-containing 6 [Source:MGI Sy... [more]
Birc62.871e-2450.49baculoviral IAP repeat-containing 6 [Source:MGI Sy... [more]
Birc62.872e-2450.49baculoviral IAP repeat-containing 6 [Source:MGI Sy... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6DG60|UBE2Z_DANRE3.109e-5047.50Ubiquitin-conjugating enzyme E2 Z OS=Danio rerio O... [more]
sp|Q66KB0|UBE2Z_XENTR8.949e-5046.50Ubiquitin-conjugating enzyme E2 Z OS=Xenopus tropi... [more]
sp|Q6PCF7|UBE2Z_XENLA1.018e-4946.50Ubiquitin-conjugating enzyme E2 Z OS=Xenopus laevi... [more]
sp|Q3UE37|UBE2Z_MOUSE5.930e-4848.17Ubiquitin-conjugating enzyme E2 Z OS=Mus musculus ... [more]
sp|Q9H832|UBE2Z_HUMAN6.633e-4848.17Ubiquitin-conjugating enzyme E2 Z OS=Homo sapiens ... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0B7A6625.828e-5250.52UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
A0A0B7A3L26.640e-5250.52UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
A0A0P4VIN31.408e-5152.06Putative inhibitor of apoptosis 1 (Fragment) OS=Rh... [more]
T1HEX43.699e-5152.06UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
A0A1I8IIU71.361e-5049.74UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2z4.303e-5047.74ubiquitin conjugating enzyme E2 Z [Source:NCBI gen... [more]
ube2g27.850e-2237.04ubiquitin conjugating enzyme E2 G2 [Source:NCBI ge... [more]
ube2a1.225e-2136.89ubiquitin conjugating enzyme E2 A [Source:NCBI gen... [more]
ENSAMXT00000050020.11.277e-2136.89ubiquitin-conjugating enzyme E2 A-like [Source:NCB... [more]
ube2al1.463e-2136.89ubiquitin-conjugating enzyme E2 A-like [Source:NCB... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2z1.674e-4452.20ubiquitin-conjugating enzyme E2Z [Source:NCBI gene... [more]
ube2t1.563e-2236.97ubiquitin-conjugating enzyme E2T (putative) [Sourc... [more]
ENSPMAT00000008817.11.895e-2236.89pep scaffold:Pmarinus_7.0:GL476329:1748443:1760143... [more]
UBE2O2.528e-2247.62ubiquitin conjugating enzyme E2 O [Source:HGNC Sym... [more]
UBE2O2.542e-2247.62ubiquitin conjugating enzyme E2 O [Source:HGNC Sym... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
UBC133.302e-2139.66E2 ubiquitin-conjugating enzyme; involved in the e... [more]
RAD61.045e-1936.07Ubiquitin-conjugating enzyme (E2); involved in pos... [more]
UBC74.812e-1937.04Ubiquitin conjugating enzyme; involved in the ER-a... [more]
UBC51.893e-1836.21Ubiquitin-conjugating enzyme; mediates selective d... [more]
UBC13.219e-1833.90Ubiquitin-conjugating enzyme; key E2 partner with ... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO495861.444e-4552.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO415562.039e-2640.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO276082.911e-2448.11pep supercontig:ASM20922v1:NEMVEscaffold_3528:46:2... [more]
EDO489195.579e-2438.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO280851.292e-2339.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2z1.227e-5047.74ubiquitin conjugating enzyme E2 Z [Source:NCBI gen... [more]
ube2a1.218e-2136.89ubiquitin conjugating enzyme E2 A [Source:NCBI gen... [more]
ube2al2.051e-2136.89ubiquitin-conjugating enzyme E2 A [Source:NCBI gen... [more]
ube2g27.450e-2137.12ubiquitin conjugating enzyme E2 G2 [Source:NCBI ge... [more]
ube2b9.387e-2136.89ubiquitin conjugating enzyme E2 B [Source:NCBI gen... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 Z vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000055888.14.154e-140100.00SMESG000055888.1[more]
SMESG000032815.11.676e-5252.69SMESG000032815.1[more]
SMESG000013882.14.488e-5147.42SMESG000013882.1[more]
SMESG000013882.15.761e-5147.67SMESG000013882.1[more]
SMESG000032815.15.782e-4759.86SMESG000032815.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014655 ID=SMED30014655|Name=Ubiquitin-conjugating enzyme E2 Z|organism=Schmidtea mediterranea sexual|type=transcript|length=852bp
TTTTGAAAAATTGTTTATTTTTATTAAGGAAATGCAAATTTTCGAAAATG
AGTGGACGTAACATGAAACGCTTAACAGCTGATATTAATAAATTTCATAA
TGATCCTCCTCATGGTATATTTTTAGATTATGATGATAAAAATCTTATTG
AAATTCACGCCTTAATTATTGGCCCAAAAGGTACTCCTTATGAAGGAGGA
TTTTTCTATTTTAAAATGGATCTACCTGCAGACTATCCACACTCTCCACC
TAAAGTAACTTTTAAAACTACTGGAAATGGAACTGTTCGATTTAATCCTA
ACTTGTATCAATGTGGTAAAGTATGCTTAAGTATTCTGGGAACTTGGTCT
GGTCCCGGTTGGACTCCAATTATGTCGATATCTACAGTTCTAATATCTAT
TCAATCATTACTTAACGAAGAACCCTACTATAATGAACCAGGTTATGAAA
ATAGTAAAAATCAAACTCAAAGTGATGCGTATAATCAAAATGTACGAATG
AATACAATGATCCACGCTGTAGAAGGCATGCTTGACAAACATACTGTAAT
GCCAAATAAATTATATTTGATTGCAAAACAATATTTTCAAGATAATTATT
CAACTTATAAAGAAACTTGCCAAAAATTTTCTTATCTTAGATCTGCAATT
AAAAGACTAGAATCTTTAAGATCTAGATTATGATTGAATTATTTAAATTT
TACATATGTTAATTACAATTTTTTATTGTTTTTACAAAAATAGTGATTTA
TATTTTTCGTAAATGTTACTCGTCTTGAATTTAAATTTAATTTGTTTGTA
GATTAGTTATTTTTATCAAGTTTATAAAAATAATGTATTTTGATCAATTT
TT
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protein sequence of SMED30014655-orf-1

>SMED30014655-orf-1 ID=SMED30014655-orf-1|Name=SMED30014655-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=227bp
LKNCLFLLRKCKFSKMSGRNMKRLTADINKFHNDPPHGIFLDYDDKNLIE
IHALIIGPKGTPYEGGFFYFKMDLPADYPHSPPKVTFKTTGNGTVRFNPN
LYQCGKVCLSILGTWSGPGWTPIMSISTVLISIQSLLNEEPYYNEPGYEN
SKNQTQSDAYNQNVRMNTMIHAVEGMLDKHTVMPNKLYLIAKQYFQDNYS
TYKETCQKFSYLRSAIKRLESLRSRL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0010951negative regulation of endopeptidase activity
GO:0006915apoptotic process
GO:0016567protein ubiquitination
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR016135UBQ-conjugating_enzyme/RWD
IPR000608UBQ-conjugat_E2
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0005524ATP binding
GO:0016740transferase activity
GO:0031625ubiquitin protein ligase binding
GO:0061630ubiquitin protein ligase activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableSMARTSM00212ubc_7coord: 22..173
e-value: 1.3E-36
score: 137.6
NoneNo IPR availablePANTHERPTHR46116FAMILY NOT NAMEDcoord: 19..178
NoneNo IPR availablePANTHERPTHR46116:SF6BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 6-RELATEDcoord: 19..178
IPR000608Ubiquitin-conjugating enzyme E2PFAMPF00179UQ_concoord: 23..165
e-value: 2.5E-34
score: 117.9
IPR000608Ubiquitin-conjugating enzyme E2PROSITEPS50127UBIQUITIN_CONJUGAT_2coord: 22..146
score: 28.864
IPR000608Ubiquitin-conjugating enzyme E2CDDcd00195UBCccoord: 21..165
e-value: 4.59343E-46
score: 147.734
IPR016135Ubiquitin-conjugating enzyme/RWD-likeGENE3DG3DSA:3.10.110.10coord: 8..225
e-value: 1.7E-69
score: 236.3
IPR016135Ubiquitin-conjugating enzyme/RWD-likeSUPERFAMILYSSF54495UBC-likecoord: 13..176