Cytochrome P450 3A31

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSI--YSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            R GL++ D     KYGK++  Y G +P+  ++D ++++ +L+K+    FT+R  +G  G + +  + + + + W+R+R+L+SPTFTSGKL++M P++    D+L + L    E   P+ +KD+FG  +MD+I  T FG++IDS  NP +PF+ + KK  KF   +P+ + I+ FP +TP+F     N     + T+NF   ++N+    R    +++  DFL  M+ +    N  + E       ++L++ E+ AQS +F+ AGYETT++ L++  Y LA +P+ QQ++ +EI  V       +Y+ +  + +L+  +NE+LR+ P A R++R C +DV        +IN     KG +  +P YA+H DP+ W EP +F   RF   SKK  SI  Y + PFG GPRNC+GMRFA++ MK+AL+ +L+ F   PC ET   +K        P KPI+LK+  R
Sbjct:   54 RQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFM-KSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEAL--NVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQ---NSKETES-----HKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDV--------EINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF---SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSR 495          

Query:  196 GLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEND-PIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            G    D+    KYGK++ FY G  P+  ++D +++K +L+K+    FT+R   G  G + +  + I + + W+R+R+L+SPTFTSGKL++M P++    D+L + L    E   P+ +KDVFG  +MD+I  T FG++IDS  NP +PF+ N KKL +F   +P  + I  FP + PI      N     R+  NF   ++ +  + R +  +++  DFL  M+ +    N  + E       ++L++ E++AQS +F+ AGYETT++ L+++ Y LA +P+ QQ++  EI  V       +Y+ +  + +L+  +NE+LR+ P A R++RVC +DV        +IN     KG V  +P YA+H DP+ W EP KF   RF  ++K     Y + PFG GPRNC+GMRFA++ MK+AL+ +L+ F   PC ET   +K        P KP++LK+  R
Sbjct:   56 GFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFM-KSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVL--NICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQ---NSKETES-----HKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDV--------EINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESR 496          

Query:   94 YKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEND-PIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            Y  GT    L KKLG  GP PLPF GN     R G +  D+    KY K++  Y    P+  ++D +++K +L+K+    FT+R   G  G + +  + I + + W+R+R+L+SPTFTSGKL++M P++    D+L + L    E   P+ +K VFG  +MD+I  T FG+ IDS  NP +PF+ N KKL +F+  +P ++ I  FP +TPI      N     R+ ++F   ++ +  + R K  +++  DFL  M+ +    N  D E       ++L++ E++AQS +F+ AGYETT++ L+++ Y LA +P+ QQ+V +EI  V       +Y+ +  L +L+  +NE+LR+ P A R++RVC +DV        +IN     KG V  +P Y +H DP+ W EP KF   RF  ++K     Y + PFG GPRNC+GMRFA++ MK+ALV +L+ F   PC ET   +K +      P KPI+LK+  R
Sbjct:   23 YLYGTRTHGLFKKLGIPGPTPLPFLGNALSF-RKGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFM-KNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEAL--NITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQ---NSKDSET-----HKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDV--------EINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRLGGLLQPEKPIVLKVESR 496          

Query:   94 YKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEND-PIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPV---KPIILKIVKR 1557
            Y  GT    L KKLG  GP PLPF GN     R G +  D+    KY K++  Y    P+  ++D +++K +L+K+    FT+R   G  G + +  + I + + W+R+R+L+SPTFTSGKL++M P++    D+L + L    E   P+ +K VFG  +MD+I  T FG+ IDS  NP +PF+ N KKL +F+  +P ++ I  FP +TPI      N     R+ ++F   ++ +  + R K  +++  DFL  M+ +    N  D E       ++L++ E++AQS +F+ AGYETT++ L+++ Y LA +P+ QQ+V +EI  V       +Y+ +  L +L+  +NE+LR+ P A R++RVC +DV        +IN     KG V  +P Y +H DP+ W EP KF   RF  ++K     Y + PFG GPRNC+GMRFA++ MK+ALV +L+ F   PC ET   +K +   FGG +   KPI+LK   R
Sbjct:   23 YLYGTRTHGLFKKLGIPGPTPLPFLGNALSF-RKGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFM-KNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEAL--NITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQ---NSKDSET-----HKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDV--------EINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLR---FGGLLLTEKPIVLKAESR 496          

Query:   94 YKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEND-PIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPV---KPIILKIVKR 1557
            Y  GT    L KKLG  GP PLPF GN     R G +  D+    KY K++  Y    P+  ++D +++K +L+K+    FT+R   G  G + +  + I + + W+R+R+L+SPTFTSGKL++M P++    D+L + L    E   P+ +K VFG  +MD+I  T FG+ IDS  NP +PF+ N KKL +F+  +P ++ I  FP +TPI      N     R+ ++F   ++ +  + R K  +++  DFL  M+ +    N  D E       ++L++ E++AQS +F+ AGYETT++ L+++ Y LA +P+ QQ+V +EI  V       +Y+ +  L +L+  +NE+LR+ P A R++RVC +DV        +IN     KG V  +P Y +H DP+ W EP KF   RF  ++K     Y + PFG GPRNC+GMRFA++ MK+ALV +L+ F   PC ET   +K +   FGG +   KPI+LK   R
Sbjct:   23 YLYGTRTHGLFKKLGIPGPTPLPFLGNALSF-RKGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFM-KNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEAL--NITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQ---NSKDSET-----HKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDV--------EINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLR---FGGLLLTEKPIVLKAESR 496          

Query:  229 KYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRL--DIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDL-LDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLF-KFSLFNPMLILILF-FPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASR-VDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            +YG+ +  YFG     ++S+EE +K++ IK+   F+DR+   I  + ++ Q +L       W+  R+ ++P F++GK++ M   +   +DL LD            D+ + F  LT+D+I +  F +  + Q + N+ F +NA+K      + +  +I   F  PE+ P++R  +        +     V  L+    ER++  E  +      +  ++E + S P          +T  E+I   F FLLAGYETT+T++TY +Y L+K P  QQ++Y EI++    +  ++Y+ I N+ +L+    E+LR  PP    ++R C  D+ +     +     KG V T   + +H++PE W  P +F   RF+N  +K+ S+  ++PFG+GPR CVGMRFA +E K  +V LL  FEL       D+I         P  P+ L +  R+
Sbjct:   73 QYGETFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQLNQSLLQNTYATGWKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREKASSGQKWDIYEDFQGLTLDVIGKCAFAIDSNCQRDRNDVFYVNARKFIANIDIRHSKVIAASFILPELAPLWRALYKYTPLADAEIP--LVEGLSNVY-ERRRGGEGSDSVDLLKLLLNREDDKSKP----------MTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEA-KENGGLTYDSIHNMKYLDYVYKETLRCYPPVIHFINRRCLADITI-----RGQFYPKGSVVTCLPHTVHLNPENWDSPEEFHPERFENWEEKSSSL-KWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFKGEADLIPDCNGVIMRPKDPVRLLLKPRN 502          

Query:  223 RDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRL--DIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDL-LDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKK-LFKFSLFNPMLILI-LFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASR-VDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
             ++YG+ +  Y+G     ++S+E+ +K++ IK+   F+DR    I    ++   +L+      W+  R+ ++P F++GK++ M   +   +DL LD            D+ D F  LT+D+I +  F +  + Q + N+ F +NAKK +    + +  +I   +  PE++  ++  +        +     V  L+    ER++  E  +      +  ++E + S P          +T  E+I   F FLLAGYETT+T++TY +Y L+K P  QQ++Y EI++    +  ++Y+ I N+ +L+    E+LR  PP    + R+C ED+ +      Q   K   V  +P + +H +PE W  P +F   RF+N  +K+ S+  ++PFG+GPR CVGMRFA +E K  +V LL  FEL       D+I         P  P+ L +  R+
Sbjct:   71 HEQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNSYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIGKCAFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVLLPELSTFWKALYKYTPLADAEIP--LVEGLSNVY-ERRRGGEGSDSVDLLKLLLNREDDKSKP----------MTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEA-KENGGLTYDSIHNMKYLDCVYKETLRFYPPVIHFIRRLCREDITI----RGQFYPKGAIVVCLP-HTVHRNPENWDSPEEFHPERFENWEEKSSSL-KWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFEGEADLIPDCNGVIMRPNDPVRLHLKPRN 502          

Query:  229 KYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLD--IGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLF-KFSLFNPMLILILF-FPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKA----------MDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRV-DRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            ++G+ +  YFG      +++EE +K++ IK+   F+DR    I  + K+ + +L       W+  R+ ++P F++GK++ M   +   +DL  + L          D+ D F  LT+D+I +  F +  + Q + N+ F +NA+K      + +  +I   F FPE++ +       W+ L R T      +L KA          + ER++  E  +      +  ++E + S P          +T  E+I   F FLLAGYETT+T++TY +Y L+K P  QQ++Y EI++    +  ++Y+ I N+ +L+    E+LR  PP     +R C +D+ +      Q   K   V  +P + +H +PE W  P +F   RF+N  +K+ S+  ++PFG+GPR CVGMRFA +E K  +  LL  FEL       D+I         P  P+ L +  R+
Sbjct:   73 QFGETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLKESLLQNTYESGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEKASSGQKWDIYDDFQGLTLDVIGKCAFAIDSNCQRDRNDVFYVNARKFITNIDIRHSKIISTSFLFPELSKL-------WKVLYRFT------DLAKAEIPLVEGLADVYERRRGGEGSDSVDLLKLLLNREDDKSKP----------MTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEA-KENGGLTYDSIHNMKYLDYVYKETLRCYPPVIHFSNRRCLKDITI----RGQFYPKGAIVVCLP-HTVHRNPENWDSPEEFHPERFENWEEKSSSL-KWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELKQFEGEADLIPDCNGVIMRPKDPVRLHLKPRN 502          

Query:  229 KYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRL--DIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLA-GIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLIL--ILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRS----LTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASR-VDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFEL 1464
            KYG I+  Y G      VS+EE +K+I I++   F+DR+  DI    ++ Q +L       W+  R+ ++P F++GK++ M   +   ID+  + L          D+ + F +L++D+I +  F +  + Q +  + F + A+K           IL   L  PE++ +       W FL      +  S+L+ A     K        L +  +A +  NDS  + L +L  R     +T  E+I   F FL+AGYETT+T++ + AY LA+ P  QQ++Y EI K    +  ++Y+ I N+ +L+    ESLR  PP +   +RVC  D+ +      QI  +   +   P Y IH +P  W  P +F   RF+N  +K+ S+  ++PFG+GPR CVGMRFA +E K  +  LL  FEL
Sbjct:   73 KYGPIFGLYCGTQLHITVSEEEDIKEIFIQNFSNFSDRMTPDIFGMNQLNQSLLQNTYATGWKHTRSAIAPIFSTGKMKAMHETLVSKIDIFLEVLKEKSSSGQKWDIFENFQSLSLDIIGKCAFAIDSNCQRDRTDLFYVQARKFVGAVDLKKSWILPVSLILPELSWL-------WRFL------YKFSDLSAAELPLVKGLVD----LYDRRRAGEGGNDST-DLLNLLIRRETIGKMTQREVIENCFAFLIAGYETTSTAMMFSAYLLAEYPIVQQKLYEEIKKT-KENAGLNYDSIHNMKYLDCVYKESLRFYPPTTHFTNRVCLNDMTI----RGQIYPEDSTLKVQP-YTIHRNPANWESPDEFQPERFENWEEKSSSL-KWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFEL 469          

Query:  229 KYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRL--DIGSNGKIGQKM-LIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKD-CIDLL---DKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKF---FPNWEFLGRQTMNFFVSNLNKAMDERKKSPE--QYNDFLTEMMKAHKEVNDSDPEQLEILDSRSL------TNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKT----RSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGP 1524
            KYGK+Y +  G     +V+D  ++ +I +K    F  R    I  N +  Q++ L+  +G  W+R+R + S +F++  L+KM   ++D  ++LL   +K+ AG    + ID+   +   TMD+I R  F M         NP +   +++F  S  N MLI  +F P I    R     FP        ++   V     A  ER+K  E  +  DF+   + A  +  D   E  E    R+L      +  E++ Q FLFL+ G++TTA SL+YV Y LA NP+ Q++V  EI + FGT  E+ +EK+  L +++  I E+LR+ P AS    +      + T+    +  + G    +  +++H DPE+W E    D+  F  E   T        +++PFG+GPR C+GMR A++E K+ L +LLK +      +T   +K   +A   P
Sbjct:   65 KYGKVYGYTDGTQRTLVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAAQGYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAG---GEQIDMLRFYQEYTMDVIGR--FAMGQTDSMMFKNPIVNVVREIFCGSRKNLMLICQVF-PPIGQFIRDLTFKFPRIPAFKLYSIMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAREDFSKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFGTS-EVEFEKLGRLKYMDCVIKEALRLYPLAS----ISNSRKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWGE----DVKEFKPERWSTDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFETGNKTRIPLKLVGSATTSP 503          

Query:  253 YFGGIPISIVSDEELLKQILIKDAKCFTDRL--DIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFF-PEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCT-----EDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPV----KPIILKIVKRS 1560
            Y    P  ++ D EL+K ++IK  + F +R+      N  +G K L   +   W  +R  +SP FTSGK+++M PLM      L      +     + VKD+    T D+IA   FG+  ++  +  + F  + + +F  +L   +   I+F  P +  + R      +   R+T  F  S++N  + ER+++ E+ ND L +++ A K    ++P ++    S+ +    ++AQ+ +F  AG+ET+A+++T   Y LAKN   Q  + +EI+  FG ++ ISYE+I  +P+L   +NE+LR  P    ++R C+     E   L    N ++    G    +   A+H DP+ WP+P K+D  RF++ ++   ++ ++MPFG+GPRNC+GMR  +L+ K+ LV++L+      C +T+  I++  T+   PV    + IIL++ K S
Sbjct:   74 YMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAERLGSGTEVQVKDLCSRFTTDLIATIAFGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLARV-----KLFSRETTKFIRSSVNYVLKERERTGEKRND-LIDILLALKREAAANPGKM----SKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMEL--PHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTS---PVMASKRDIILRVEKVS 506          

Query:  253 YFGGIPISIVSDEELLKQILIKDAKCFTDRL--DIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFF-PEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCT-----EDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPV----KPIILKIVKRS 1560
            Y    P  ++ D EL+K ++IK  + F +R+      N  +G K L   +   W  +R  +SP FTSGK+++M PLM      L      +     + VKD+    T D+IA   FG+  ++  +  + F  + + +F  +L   +   I+F  P +  + R      +   R+T  F  S++N  + ER+++ E+ ND L +++ A K    ++P ++    S+ +    ++AQ+ +F  AG+ET+A+++T   Y LAKN   Q  + +EI+  FG ++ ISYE+I  +P+L   +NE+LR  P    ++R C+     E   L    N ++    G    +   A+H DP+ WP+P K+D  RF++ ++   ++ ++MPFG+GPRNC+GMR  +L+ K+ LV++L+      C +T+  I++  T+   PV    + IIL++ K S
Sbjct:   74 YMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAERLGSGTEVQVKDLCSRFTTDLIATIAFGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLARV-----KLFSRETTKFIRSSVNYVLKERERTGEKRND-LIDILLALKREAAANPGKM----SKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMEL--PHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTS---PVMASKRDIILRVEKVS 506          

Query:  211 DIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGK---------IGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLM----KDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILF-FPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDE--EISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFG-GPVKPIILKIVKRS 1560
            D+  +    K +  +    P+ +V D +L+KQI IKD   F +  ++ +            +    L  ++   W+ +R+ +SP FT  K+R+M  LM    K+ +D L +  + + EN+ +D+KD     T D+IA T FG+ ++S  +  N F    KKL  F+    M  ++ F    +  I +      E   R++  +FV  +  AM  R++      D +  +M+A   +     E+ +    R  ++ +I+AQ F+F  AG+ET+A  + + A+ L +N + QQ +Y E+ +V    E  E++YE I  + +L+  +NE LR  P A  VDR C +D+     D +++  KKGDV  +P    H DP+ +  P KFD  RF +E+K++   +++ PFG+G RNC+G RFA+LE K  +  LLK +   P  ++   ++   + F   P     +K+V+R+
Sbjct:   60 DLYTKGGSKKFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENE-LDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNKILKV-----ELFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQ---TEKTKASAVREWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITF-DVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGFWIKLVQRN 516          

Query:  223 RDKYGKIYPFYFGGIPIS----------IVSDEELLKQILIKDAKCFTDR---LDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCI----DLLDKRL--AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDE--EISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAF 1515
            RD   +IY  + G  PI+          +++D + +KQ++IKD   F DR    +   +   G   L  L+G+ W  +R+ ++P FTSGK+++MS ++ D      D +DK +  A + E + +++KD+    T D+I    FG+  +S  +P+  F    +++F     + ++   +F      + RK     + L      FF+S +   +D R K+  + NDF+ +M++   E  ++  +   I  S  LT  ++ AQ+F+F +AG+ET++++++   Y LA  P+ QQ +  EI  V    +  E++Y+ ++ + +L+  ++E+LR  P    + R  T+D  +  SD   I   KG +  +P++ IH DPEI+PEP KFD SRFD E  K R   +++PFG GPRNC+G+RF  ++ K+ LV+LL++F+      T   + F K +F
Sbjct:   53 RDINQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGH--LFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN-VEIKDLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIF--TNARLARKL--RIKVLPDDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSD---IVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSF 494          

Query:  223 RDKYGKIYPFYFGGIPIS----------IVSDEELLKQILIKDAKCFTDR---LDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCI----DLLDKRL--AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDE--EISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAF 1515
            RD   +IY  + G  PI+          +++D + +KQ++IKD   F DR    +   +   G   L  L+G+ W  +R+ ++P FTSGK+++MS ++ D      D +DK +  A + E + +++KD+    T D+I    FG+  +S  +P+  F    +++F     + ++   +F      + RK     + L      FF+S +   +D R K+  + NDF+ +M++   E  ++  +   I  S  LT  ++ AQ+F+F +AG+ET++++++   Y LA  P+ QQ +  EI  V    +  E++Y+ ++ + +L+  ++E+LR  P    + R  T+D  +  SD   I   KG +  +P++ IH DPEI+PEP KFD SRFD E  K R   +++PFG GPRNC+G+RF  ++ K+ LV+LL++F+      T   + F K +F
Sbjct:   53 RDINQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGH--LFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN-VEIKDLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIF--TNARLARKL--RIKVLPDDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSD---IVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSF 494          

Query:   67 LCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSN--GKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAH---KEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            L F+VI L+Y  G       KKLG  GP P PFFG F    + G +  D+    KYGK++  Y G +PI +V+D E++K I++K+    FT+R ++  +  G +   +  + K + W+R+R  +SP FTSG+L+++ P+     D   K +       P+ +K+V    ++D++  + F + IDS  NP++PF+ N K   KFSLF+P+++ +  FP I  +  K         R  MNFF + L K  DE K S  +  DFL  M++      +  D+  EQ      + LT+ EI++QSF+F+L GYETT+T+L+++ + LA NP+  +++  EI K F  D  ISY+ +  + +LE +INES+R+ P A R++RVC + V L       I   K  +  +P Y ++ DP++W  P +F   RF  E+K     Y+FMPFG+GPRNC+GMRFA++ +K+ +V LL+ F L  C ET   I  + T    P  PI LK+  R
Sbjct:   13 LVFLVITLLYMYGVWPHGFFKKLGIPGPRPWPFFGTFLSYTK-GFFNFDMECAKKYGKVWGIYDGRLPILMVTDLEMIKTIMVKECYSTFTNRREVNVDLAGPLADGISAV-KDERWKRIRGTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKRDHEQPVKIKEVVAPYSLDVVTSSSFSVDIDSINNPDDPFVTNIKNFLKFSLFSPLILFLTLFPSIANLLGKM--GISVFSRSIMNFFYTALRKIKDEHKDSNGRV-DFLRLMIQNQIPDDQAKDTTSEQ----PVKGLTDHEILSQSFIFILGGYETTSTTLSFLLHNLATNPDCLEKLVEEIDKNFPLDTPISYDALMKMDYLEMSINESMRLLPTAPRLERVCKKTVEL-----NGITIPKDTLVAIPTYVLNRDPQLWDSPQEFRPERFSPENKSEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVKLLQNFSLETCKET--QIPLELTPVFQPKVPITLKLTPR 499          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLL-DKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDER------KKSPEQYNDFLTEMMKAHKEV-NDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            + G +  D+   +KYG+I+  Y G  P+  + D+ ++K +LIK+    FT+R +   NG +    + I +   W R+R+++SP+FTSG+L++M  +MK    +L D         +  D+K+ FG  +MD++  T F + IDS  NP +PF+ N KK+ KF L NP+ +LI FFP + P+  K   ++        +FF + L K   +R      K + ++  DFL  M+ +   V + SD E  E    + L++ EI++QS +F+ AGYET++++L+++ Y LA NPE  +++  EI + F     + YE + ++ +L+AA++ESLR+ P A+R++RVC + V        +IN     K  V  VP YA+H DP+ W EP  F   RF   +K++   Y +MPFG+GPRNC+GMRFA + MK+A+V +L++F++  C ET   ++        P  PI LK+  R
Sbjct:   50 KDGFHVFDMDCFEKYGRIWGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNFRLNGAL-YDAVSIAEDDDWRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGESADIKEFFGAYSMDVVTSTAFSVDIDSLNNPKDPFVTNIKKMLKFDLLNPLFLLIAFFPFMAPVLEKM--DFALFPTSVTDFFYAALQKIKSDRDTKTVAKDNTKKRVDFLQLMVDSQTGVKHKSDGEHTE----KGLSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETFPNQAPVDYETLMSMDYLDAALSESLRLYPVAARLERVCKKTV--------EINGLLIPKDLVVMVPTYALHRDPDYWSEPESFKPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGFNGLLSPKDPIKLKLQPR 502          

Query:  184 IIRHGLY--ELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEND-PIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMN-FFVSNLNKAMDERKK-SPEQYN-DFLTEMMKAHKE-----------VNDSDPEQLEILDS-------------RSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LID 1572
            + R+G +  + D+IN  KYG+I  +Y G     I++D ++L+Q+++K+   F +R+      K     LI+LKG+ W+RVR++++PTF++ K+++M PL+    + L + L    E++   ++   FG  TMD+IA   FG  +DSQ NP++PF+  A K F FS F P++I  + FP +  +     PN     R  MN FF   + K + +R   SPEQ   DFL  M+                VND+D E  +  ++             R +T  EI+ QSF+FL+AGYET++ +L +  Y LA +PE Q+++  E+ + F   E + Y  +  L +L+  I ESLR+ PPA RV R   ED VL    N Q    KG    +P   +H DPE W EP KF   RF  E+K  R  + ++PFG GPR+CVGMR A LE+K+ALV++ ++F ++ C +T   ++ K     GP   +++KI +R  L D
Sbjct:   62 MFRNGFFKSQADLIN--KYGRICGYYIGRRSTVIIADPDMLRQVMVKEFNKFPNRMTARGITKPMSDSLIMLKGEQWKRVRSILTPTFSAAKMKEMVPLINTATETLLRNLKSHAESENSFNIHKCFGCFTMDVIASVAFGTQVDSQNNPDDPFVHQASKFFAFSFFRPIMIFFMAFPFLLRLLAGLLPN---KSRDEMNSFFTQCIQKMIKQRDDLSPEQRRKDFLQLMLDVRTNKKFLSVEHFDVVNDADEEAYDGHENSPANESTKRSQQKRMMTEDEIVGQSFIFLVAGYETSSNTLAFTCYLLAVHPECQKKLQEEVDEFFSRHETVDYANVQELKYLDMVICESLRLYPPAFRVARDVEEDTVL----NGQF-LPKGASLEIPTGFLHYDPEHWTEPTKFIPERFTPEAKARRHPFVYLPFGAGPRSCVGMRLAQLEIKVALVHIFRRFNVLACEDTEIPLELKSHTTLGPKNGVMVKITERENLED 544          

Query:  196 GLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLD-----IGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAH---KEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            GL   D+    KYGK++  Y G +PI +V+D E++K +L+K+  C+++ ++      G  G      +I++K + W+R+R+ +SP FTSG+L+++ P+     D   K +       P+ +K+V    ++D+I  + F + IDS  NP +PF+IN KK  +F++FNP+L+LIL FP +    +K         +  M+FF S L K  D+  K  E   DFL  M++      ++ DSD  +     ++ LT+ EI++QS +F+L GYETT+T+LT++ Y LA NP+  +++  EI K F  D  I+Y+ +  + +LE AINES+R+ P A R++R   + VV+       +   +G +  +P Y +  DP+IW  P +F   RF  E+K     Y+F+PFG+GPRNC+GMR+AV+ MK+ +V LL+ F +  C ET   ++   T    P  PI LK++ RS
Sbjct:   55 GLCNFDMECAKKYGKVWGIYDGRLPILMVTDLEVIKVVLVKE--CYSNFINRRKRTTGLAGPFSDG-IIMVKDERWKRMRSTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKKDPEQPVKIKEVVAPYSLDVITSSSFSVDIDSINNPEDPFVINVKKFIQFNMFNPLLLLILLFPSLAIPLKKM--GVTLFSKSAMDFFYSVLKKIKDDHNKESEGRVDFLKLMLQNQIPDDQIQDSDTSEQP---AKGLTDHEILSQSLVFILGGYETTSTTLTFLLYNLATNPDCLEKLVEEIDKNFPLDTPITYDALMRMDYLEMAINESMRLLPTAPRLERSAKKTVVI-----NGLTIPEGTLVGIPTYVLSHDPDIWESPGEFRPERFSPENKSEFLQYAFIPFGLGPRNCIGMRYAVMIMKLFVVKLLQNFSVETCKETQIPLEINVTF--QPKVPITLKLIPRS 502          

Query:  196 GLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSN--GKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAH---KEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            G +  D+    KYGK++  Y G +PI +V+D E++K I++K+    FT+R +I  +  G +   +  + K + W+R+R  +SP FTSG+L+++ P+     D   K +       P+ +K+V  + ++D++  + F + IDS  NP++PF+ N K   KF+LF   ++L+  FP I  +  K         + T++FF   L K  +E K S  +  DF   M++      +V D+  EQ E    + LT+ EI++QSF+F++ GYETT+T+LT++ Y LA NP+  +++  +I K F  D  ISY+ +  + +LE +INES+R+ P A R++RVC + V +       I   K  + T+P Y ++ DP++W  P++F   RF  E+K     Y+FMPFG+GPRNC+GMR+A++ +K+ +V LL+ F +  C ET   I  +      P  PI LK+  R
Sbjct:   34 GFFNFDMECAKKYGKVWGIYDGRLPILMVTDLEMIKTIMVKECYSTFTNRREINVDLAGPLADGITAV-KDERWKRIRGTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKGDHEQPVKIKEVMASYSLDVVTSSAFSVDIDSINNPDDPFVTNIKNFLKFNLFGLFVLLLTVFPSIANLLGKM--GLSMFSKPTVDFFYKALRKIKEEHKDSNGRV-DFFRLMIQNEIPDDQVKDTTSEQPE----KGLTDHEILSQSFIFIMGGYETTSTTLTFLLYNLAINPDCLEKLVEKIDKNFPLDTPISYDALMKIDYLEMSINESMRLLPTAPRLERVCKKTVEM-----NGITIPKDTMITIPTYVLNQDPQLWDSPHEFRPERFSPENKSEFLQYAFMPFGLGPRNCIGMRYALMIVKLLVVKLLQNFSVETCKET--QIPLELNPVFQPKVPITLKLTPR 478          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKK-SPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            RHGL E D+    KYGK++  Y G  P+  + D  ++K I++K+    FT+R D G +G +   +LI  K + W+R+R ++SPTFTSGKL++M PLM    +LL K +   I   +P+D+K +FG+ +MD++  T F +++DS  NPN+PF+ NA+ LF FS FNP+ ++ +  P + P+  K   N+ FL  + +NFF   +     +R+K + E   DFL  M+ A      S PE+ E    + L+++EI+AQS +F++AGYETT+T+L ++AY +A +P+ Q+++  EI  +       +Y+ +  + +++  INESLR+ PPA R+DRVC +     T +   +    G V  VP++A+H++PEIWPEP +F   RF  E++K +  Y+F+PFG+GPRNC+GMRFA++ MK+AL  LL+ F L  C +T   +K     +  P KPIIL ++ +
Sbjct:   46 RHGLMEFDMECFKKYGKVWGIYEGQKPLLAIVDPVIIKSIMVKECYTNFTNRRDFGLSGPLKSSVLIS-KDEQWKRIRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNKEPLDMKHIFGSYSMDIVLSTSFSVNVDSMNNPNDPFVTNARNLFTFSFFNPLFLISILCPFLVPLLDKM--NFCFLSLKILNFFKDAVASIKKKRQKGTHEDRVDFLQLMVDAQSNEGKSVPEE-EKHGYKELSDTEILAQSLIFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEIDALLPNKAPPTYDALMKMEYMDMVINESLRMFPPAIRIDRVCKK-----TMEINGVTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLPFGVGPRNCIGMRFALVNMKVALTILLQNFRLETCKDTPVPLKICTKGYLKPTKPIILNLIPK 495          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKK-SPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            R GL E D+    KYGK++  Y G  P+  + D  ++K I+IK+    FT+R D+G  G +   +L+  K + W+R+R ++SPTFTSGKL++M PLMK   +LL K +   I   +P+D+K +FG+ +MD++  T F +++DS  NPN+PF+ NA+ LFKFS FNP+ ++ +  P + P+  K   N+ FL  + +NFF   +     +R+K + E   D L  M+ A     +S PE+ E    + L+++EI+AQS +F++AGYETT+T+L ++AY +A +P+ Q+++  EI  +       +Y+ +  + +++  INE+LR+ PPA R+DRVC +     T +   +    G V  VP++ +H++PEIWPEP +F   RF  E++K +  Y+F+PFG+GPRNC+GMRFA++ MK+ L  LL+ F    C +T   +K     +  P KPIIL ++ ++
Sbjct:   54 RKGLMEFDMECFKKYGKVWGIYEGQKPLLAIVDPVIIKSIMIKECYSNFTNRRDLGLTGPLKSSVLVS-KDEQWKRIRTVLSPTFTSGKLKQMFPLMKHYGELLVKNIHKKIDNKEPLDMKHIFGSYSMDIVLSTSFSVNVDSMNNPNDPFVTNARNLFKFSFFNPLFLIAILCPFLVPLLDKM--NFCFLSLKILNFFKDAVASIKKKRQKGTHEDRVDLLQLMVDAQSNEGESVPEE-EKHGYKELSDTEILAQSLIFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEIDALLPNKAPPTYDALMKMEYMDMVINETLRMFPPAIRIDRVCKK-----TMEINGVTIPAGVVIVVPLFVLHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLPFGVGPRNCIGMRFALVNMKLVLTILLQNFRFETCKDTPVPLKICTDGYLKPTKPIILNLIPKA 504          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            RHGL E D+    KYG ++ FY G  P+  + D  ++K I++K+    FT+R D G +G +   +L+  K + W+R+R ++SPTFTSGKL++M PLMK   +LL K +   I   +P+D+K +FG+ +MD I  T F +++DS  NPN+PF+ NA+ LF FS F P+ ++ +  P + P+  K   N+ FL  + + FF   +     +R+K       DFL  M+ A     +S PE+ E    + L+++EI+AQS +F++AGYETT+T+L ++ Y +A+ P+ Q+++  EI  +       +Y+ +  + +++  INE+LR+ PPA R+DRVC +     T +   +    G V  VP++A+H++PEIWPEP +F   RF  E++K +  Y+F+PFG+GPRNC+GMRFA++ +K+AL  LL+ F+L  C +T   +K        P KPIIL +V + 
Sbjct:   54 RHGLMEFDMKCFKKYGNVWGFYDGPQPVLAILDPVIIKSIMVKECYTNFTNRRDFGLSGPLKSSVLMS-KDEQWKRIRTVLSPTFTSGKLKQMFPLMKHYGELLVKNIHKKIDNKEPLDMKSIFGSYSMDTILSTSFSVNVDSMNNPNDPFVTNARNLFTFSFFKPLFLITILCPFLVPLLDKM--NFCFLSSKFLKFFKDAVASIKKKRQKGAHMDRVDFLQLMVDAQSNEGESVPEE-EKHRHKELSDTEILAQSLIFIMAGYETTSTTLMFLTYNIARYPDVQRKLEEEINTLLPNKAPPTYDALMKMEYMDMVINETLRLLPPAIRIDRVCKK-----TMEINGVTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLPFGVGPRNCIGMRFALVNIKLALTILLQNFKLETCKDTPVPLKVCTRGNLKPTKPIILNLVPKG 504          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKK-SPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAET 1482
            RHGL E D+    KYGK++  Y G  P+  + D  ++K I++K+    FT+R D G +G +   +LI  K + W+R+R ++SPTFTSGKL++M PLM    +LL K +   I   +P+D+K +FG+ +MD++  T F +++DS  NPN+PF+ NA+ LF FS FNP+ ++ +  P + P+  K   N+ FL  + +NFF   +     +R+K + E   DFL  M+ A      S PE+ E    + L+++EI+AQS +F++AGYETT+T+L ++AY +A +P+ Q+++  EI  +       +Y+ +  + +++  INESLR+ PPA R+DRVC +     T +   +    G V  VP++A+H++PEIWPEP +F   RF  E++K +  Y+F+PFG+GPRNC+GMRFA++ MK+AL  LL+ F L  C +T
Sbjct:   46 RHGLMEFDMECFKKYGKVWGIYEGQKPLLAIVDPVIIKSIMVKECYTNFTNRRDFGLSGPLKSSVLIS-KDEQWKRIRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNKEPLDMKHIFGSYSMDIVLSTSFSVNVDSMNNPNDPFVTNARNLFTFSFFNPLFLISILCPFLVPLLDKM--NFCFLSLKILNFFKDAVASIKKKRQKGTHEDRVDFLQLMVDAQSNEGKSVPEE-EKHGYKELSDTEILAQSLIFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEIDALLPNKAPPTYDALMKMEYMDMVINESLRMFPPAIRIDRVCKK-----TMEINGVTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLPFGVGPRNCIGMRFALVNMKVALTILLQNFRLETCKDT 470          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEND-PIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            R G+ + D     KYGK++  Y G  P+  + D  ++K IL+K+    FT+R + G NG   +  + I + + W+R+RN++SPTFTSGKL++M  +MKD  D+L K + G  E D P   KDV G  +MD+I  T F ++IDS   P++PF+I+ KKL K  L +P+LIL++ FP + PI      N  F+ +    FF++ +    ++RKK        L ++M   +    +D         ++LT++EI+AQS +F++AGYETT+T+L+Y+ Y LA +P+ QQ ++ EI          +Y+ +  + +L+  I E+LR+ PPA R++RV  ++V +       ++  KG V  +P Y +  DPE WPEP +F   RF  E++ T + ++F+PFG GPRNC+G+RFA+L MK+A+V+LL+ F + PCAETL  ++F    F  P KPI+LK + R+
Sbjct:   43 RKGMVQFDTECFKKYGKMWGTYDGRQPVLAIMDPAIIKTILVKECYTNFTNRRNFGLNGPF-ESAITIAEDEQWKRIRNVLSPTFTSGKLKEMFQIMKDYSDILVKNIQGYVEKDEPCATKDVIGAYSMDVITSTSFSVNIDSLNKPSDPFVIHMKKLLKTGLLSPLLILVVIFPFLRPILEGL--NLNFVPKDFTEFFMNAVTSFREKRKKGDHSGRVDLLQLMMDSRTTGGNDLSN----KHKALTDAEIMAQSVIFIVAGYETTSTALSYLFYNLATHPDVQQRLHEEIDSFLPDKASPTYDILMQMEYLDMVIQETLRLFPPAGRLERVSKQNVEI-----NGVSIPKGIVTLIPAYVLQRDPEYWPEPEEFRPERFSKENRATHTPFTFLPFGDGPRNCIGLRFALLSMKVAIVSLLQNFSVRPCAETLIPMEFSTIGFLQPKKPIVLKFLSRA 489          

Query:   64 LLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LI 1569
            +L  + + L+Y+ GT K  L KK G  GP PLPF G   +  + GL++ D+    KYGK +  + G  P+  V+D E +K +L+K+    FT+R D G  G I  K + I K   W+R R L+SPTFTSGKL++M P+++   D+L K L     +  P+ +KDV G  +MD+I  T FG+++DS  NP +PF+  AKKL +F  F+P+L  ++ FP +TP++     N     + ++ FF   +++  + R  S +++  DFL  MM +H    D        +  ++L++ EI AQS +F+ AGYETT+++L++  + LA +P+ Q+++  EI +        +Y+ +  + +L+  +NE+LR+ P A+R++RVC +DV L       +   KG    +P YA+H DP+ W EP +F   RF  E+K +   Y ++PFG GPRNC+GMRFA++ MK+AL  +++ F   PC ET   +K  +     P KPI+LK+V R  +I
Sbjct:   13 VLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYK-GLWKFDMECYKKYGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVG-IMSKAISISKDDEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVITSTSFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEML--NICMFPKDSIEFFKKFVDRMKESRLDSKQKHRVDFLQLMMNSHNNSKDK-------VSHKALSDMEITAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVEL-----NGVYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQGLLQPEKPIVLKVVPRDAVI 501          

Query:   64 LLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPE-QYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            +L    + L+Y  GT    + KKLG  GP PLPF G      + G +E DI    KYGK++  Y G  P+  ++D +++K +L+K+    FT+R   G  G I +K + I + + W+R+R L+SPTFTSG+L++M P++    D+L + +  G+ E  P  +KD+FG  +MD+I  T FG++IDS  NP +PF+   KKL KF +F+P+ + +  FP +TP+F     N     R  ++FF +++ +  + R K  E Q  DFL  M+ +                 ++L++ EI+AQS +F+ AGYETT+++L++  Y LA +P+ Q+++  EI          +Y+ +  + +L+  +NE+LR+ P A R++RVC  DV        +IN     KG V  +P +A+H DP+ WPEP +F   RF  +++ + + Y ++PFG GPRNC+GMRFA++ MK+ALV +L+ F + PC ET   +K  K     P  P++LK+V R
Sbjct:   13 MLLATSLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTIL-AYQKGFWECDIQCHKKYGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVG-ILKKAISISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSMDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDAL--NVSLFPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKES--------HKALSDVEIVAQSVIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDV--------EINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQGLLQPENPLLLKVVSR 496          

Query:   61 LLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            LL+  +V+F IY  GT    L KKLG  GP PLP  G  F+    G+++ D     KYGKI+ FY G  PI  + D E++K +L+K+    FT+R   G  G + +K + I + + W+R+R L+SPTFTSGKL++M P+M+   D+L + L    E  +PI +KD+FG  +MD+I  T FG+++DS  NP +PF+  AKK+ KF +F+P L+ I+ FP +TPI+     N+    R +MNFF   + +   ER  S ++   DFL  MM                   ++L++ E+ AQ+ +F+  GY+ T+TS++ + Y LA +P+ Q+++  EI +       ++Y+ + ++ +L+  +NESLR+ P A R++RV  +DV        +IN     KG V  +PIY +H +PE WPEP +F   RF  E+K     Y +MPFG GPRNC+GMRFA++ +K+A++ +L+ F + PC ET   +K  +     P KPIILK+V R
Sbjct:   14 LLVTSLVLFYIY--GTYSHGLFKKLGIPGPKPLPLLGTIFNYY-DGMWKFDEDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFM-KKAITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIYEML--NFSIFPRDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNSKGQES--------QKALSDLEMAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDV--------EINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISREPIFQPEKPIILKVVSR 496          

Query:   61 LLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            LL+  +V F IY  GT    L KKLG  GP PLP FG  F+    G+++ D     KYGKI+ FY G  PI  + D E++K +L+K+    FT+R  +G  G + +K + I + + W+R+R L+SPTFTSGKL++M P+M+   D+L + L    E  +PI++KD+FG  +MD+I  T FG++IDS  NP NPF+   KK+ KF +F+P L+  + FP +TPI+     N     R +MNFF   + +   ER  S ++   DFL  MM                   ++L++ E+ AQ+ +F+  GY+ T+TS++ + Y LA +P+ Q+++  EI +       ++Y+ + ++ +L+  +NESLR+ P A R++RV  +DV        +IN     KG V  +PIY +H +PE WPEP +F   RF  E++     Y +MPFG GPRNC+ MRFA++ MK+A++ +L+ F + PC ET   +K  +     P KPIILK+V R
Sbjct:   14 LLVTSLVFFYIY--GTYSHGLFKKLGIPGPKPLPLFGTIFNYF-DGMWKFDEDCYKKYGKIWGFYVGPKPILAIMDPEIIKIVLVKECYSVFTNRPTLGPVGFL-KKSITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFGAYSMDVITGTSFGVNIDSLNNPQNPFVQKTKKILKFKIFDPFLLSTILFPFLTPIYEML--NLSIFPRDSMNFFKKFVKRMKKERLASKQKNRVDFLQLMMNTQNSKGQES--------QKALSDLEMAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYPTAIRLERVSKKDV--------EINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPGRFSKENEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQIPLKISREPVFQPEKPIILKVVSR 496          

Query:   94 YKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LI 1569
            Y+ GT    L KK G  GP PLPF G   +  + GL++ D+   +KYGK +  + G +P+ +++D E++K +L+K+    FT+R + G  G I  K + I K + W+R R L+SPTFTSGKL++M P+++   D+L K L    E   P+ +KDV G  ++D+I  T FG+++DS  NP +PF+  AK + +   F+P++  ++ FP +TP++     N     + ++ FF   +N+  + R  S +++  DFL  MM AH    D D         ++L++ EI AQS +F+ AGYETT+++L++  Y LA +P+ Q+++  EI +        +Y+ +  + +L+  +NE+LR+ P  +R++R C +DV L       +   KG    +P YA+H DP+ WPEP +F   RF  E+K +   Y +MPFG+GPRNC+GMRFA + MK+AL  +++ F   PC ET   +K  +     P KPI+LK+V R  +I
Sbjct:   23 YRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYK-GLWKFDMECYEKYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVG-IMSKAISISKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEML--NICMFPKDSIEFFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKDKD-------SHKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVEL-----NGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLLQPEKPIVLKVVPRDVVI 501          

Query:   64 LLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LI 1569
            +L  + + L+Y+LGT K ++ KK G  GP PLPF GN  +  + G++  DI    KYGKI+  + G  P+  V+D E++K +L+K+    FT+R D G  G I  K + I K + W+R+R L+SPTFTSGKL++M P+++   D+L K L    E  +P+  K+VFG  +MD+I  T FG+ +DS  NP +  +   +KL +F  F+P+ + ++ FP + PI+ K   N     + +++FF   ++K  + R    +++  DFL  MM +H    DS          ++L++ EIIAQS +F+ AGY+TT+++L++  Y LA +P+ Q+++  EI          SY+K+  + +L+  +NE+LR+ P  SR++RVC +DV     +   +   KG +  VP++A+H DP+ WPEP KF   RF  E+K +   Y F+PFG GPRNC+GMRFA++ MK+AL  +L+ F L PC ET   +K  + A   P KPIILK+V R  +I
Sbjct:   13 VLLAISLVLLYRLGTHKYDIFKKQGIPGPKPLPFLGNVLNYYK-GIWTFDIECHKKYGKIWGLFEGQRPLFTVTDTEMIKNVLVKECYSIFTNRRDFGPVG-IMSKAVSISKDEEWKRIRALLSPTFTSGKLKEMFPIIEQYGDILVKFLRREAEKGNPVTTKEVFGAYSMDVITSTAFGVSVDSLNNPKD-LLWKGRKLLRFDFFDPLFLSVVLFPFLIPIYEKL--NVSMFPKDSISFFRKFVDKTKENRLDYNQKHRVDFLQLMMNSHDNSKDS---------HKALSDMEIIAQSIIFIFAGYDTTSSTLSFALYLLATHPDVQKKLQEEIDIALPNKARPSYDKVMEMEYLDMVLNETLRLYPIGSRLERVCKQDV-----EMDGVFVPKGSIVMVPVFALHYDPQYWPEPEKFRPERFSKENKGSIDPYIFLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSLQPCKETQIPMKLSRKAMLQPEKPIILKVVPRDAII 498          

Query:   94 YKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEND-PIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LID 1572
            Y+LGT +  + KK G  GP PLPF G   +  + GL   D+    KYGKI+  + G  P+  + D E++K +L+K+    FT+R D G  G +G K + + K + W+R R L+SPTFTSG+L++M P+++   D+L K L    E   P+ +K VFG  +MD+I  T FG+++DS  NP +PF+   KKL +F  F+P+ + ++ FP +TPI+     N     + ++ FF   +++  + R  S  ++  DFL  M+ AH    D        +  ++L++ EIIAQS +F+ AGYETT+++L++V YFLA +P+ Q+++  EI     +    +Y+ +  + +L+  +NE+LR+ P  +R++RVC +D+ L       +   KG V T+P YA+H DP+ WP+P +F   RF  E+K +   Y ++PFG GPRNC+GMRFA++ MK+AL  +L+ F   PC ET   +K  + A   P KPI+LK++ R  +I+
Sbjct:   23 YRLGTHRHGIFKKQGIPGPKPLPFLGTVLNYYK-GLGRFDMECYKKYGKIWGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVGIMG-KAVSVAKDEEWKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTMKKVFGAYSMDVITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEML--NICMFPKDSIAFFQKFVHRIKETRLDSKHKHRVDFLQLMLNAHNNSKDE-------VSHKALSDVEIIAQSVIFIFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKAPPTYDIVMEMEYLDMVLNETLRLYPIGNRLERVCKKDIEL-----DGLFIPKGSVVTIPTYALHHDPQHWPKPEEFHPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQAILEPEKPIVLKVLPRDAVIN 502          

Query:   34 MIEYFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            +I  F     +L    + L+Y  GT    L KKLG  GP PLP+FGN     R G+   D     +YGK++  Y G  P+  V+D  ++K +L+K+    FT+R   G  G + +  L + + + W+R+R L+SPTFTSGKL++M P++    DLL   L    E   P+ +KD+FG  +MD+I  T FG++IDS  NP +PF+ N+KKL KFS F+P L+ ++FFP +TPIF     N     + ++NFF  ++ +  + R    ++    L ++M   +   + DP        +SL+N E++AQ  +F+ AGYETT+++L+ +AY LA +P+ QQ++  EI   F      +Y+ ++ + +L+  +NE+LR+ P A+R++R C +DV +       +   KG V  VP++ +H DP++WPEP +F   RF  + K T + Y+++PFG GPRNC+GMRFA++ MK+ALV +L+ F   PC ET   +K        P KP++LKI+ R
Sbjct:    3 LIPGFSTETWVLLATSLVLLYLYGTYSHGLFKKLGIPGPRPLPYFGNILGY-RKGVDHFDKKCFQQYGKMWGVYDGRQPLLAVTDPNMIKSVLVKECYSVFTNRRSFGPLGAM-RNALSLAEDEEWKRIRTLLSPTFTSGKLKEMFPIISHYGDLLVSNLRKEAEKGKPVTMKDIFGAYSMDVITSTAFGVNIDSLNNPQDPFVENSKKLLKFSFFDPFLLSLIFFPFLTPIFEVL--NITLFPKSSVNFFTKSVKRMKESRLTDQQKRRVDLLQLMINSQNSKEMDPH-------KSLSNEELVAQGIIFIFAGYETTSSALSLLAYELATHPDVQQKLQEEIEATFPNKAPPTYDALAQMEYLDMVVNETLRLYPIAARLERACKKDVEI-----HGVFVPKGTVVVVPVFVLHRDPDLWPEPEEFRPERFSKKHKDTINPYTYLPFGTGPRNCIGMRFALMNMKLALVRVLQNFSFKPCKETQIPLKLTTQGLTQPEKPVVLKILPR 496          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPE-QYNDFLTEMMKAH-KEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            R G +E D     KYGK++  Y G  P+  ++D +++K +L+K+    FT+R + G  G I +K + I + + W+R+R L+SPTFTSGKL++M P++    D+L + +  G  E  P  +KD+FG  +MD+I  T FG+++DS  NP +PF+   KKL KF +F+P+ + +  FP +TP+F     N     R  ++FF +++ +  + R K  E Q  DFL  M+ +   +V DS          ++L++ EI+AQS +F+ AGYETT+++L++V Y LA +P+ Q+++  EI          +Y+ +  + +L+  +NE+LR+ P A R++RVC  DV        +IN     KG V  +P +A+H DP  WPEP +F   RF  +++   + Y ++PFG GPRNC+GMRFA++ MK+AL  +L+ F   PC ET   +K  K     P KP++LK+V R
Sbjct:   54 RKGFWEFDKYCHKKYGKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVG-ILKKAISISEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVITATSFGVNVDSLNNPQDPFVEKVKKLLKFDIFDPLFLSVTLFPFLTPLFEAL--NVSMFPRDVIDFFKTSVERMKENRMKEKEKQRMDFLQLMINSQNSKVKDS---------HKALSDVEIVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDV--------EINGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSFQPCKETQIPLKLSKQGLLQPEKPLLLKVVSR 496          

Query:  196 GLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEND-PIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LI 1569
            GL++ D+    KYGKI+  + G +P+  ++D E++K +L+K+    FT+R D G  G +G K + + K + W+R R L+SPTFTSG+L++M P+++   D+L K L    E   P+ +K VFG  +MD+I  T FG+++DS  NP +PF+   KKL +F  F+P+ + ++ FP +TPI+     N     + ++ FF   + +  + R  S +++  DFL  MM AH +  D +          +L++ EI AQS +F+ AGYE T+++L++V + LA +P+ Q+++  EI +        +Y+ +  + +L+  +NE+LR+ P  +R++RVC +DV        +IN     KG V  +P YA+H DP+ WPEP +F   RF  E+K +   Y ++PFG GPRNC+GMRFA++ MK+AL  +L+ F   PC ET   +K  +     P KPIILK+V R  +I
Sbjct:   56 GLWKFDVECHKKYGKIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMG-KAVSVAKDEEWKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTMKKVFGAYSMDVITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEML--NICMFPKDSIEFFKKFVYRMKETRLDSVQKHRVDFLQLMMNAHNDSKDKE-------SHTALSDMEITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERVCKKDV--------EINGVFMPKGSVVMIPSYALHRDPQHWPEPEEFRPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQGLLQPTKPIILKVVPRDEII 501          

Query:   64 LLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LI 1569
            +L  + + L+Y+LGT K ++ KK G  GP PLPF G      + G+++ DI  R KYGKI+  + G  P+  V+D E++K +L+K+    FT+R D G  G I  K + I K + W+R+R L+SPTFTSGKL++M P+++   D+L K L    E   P+  K+VFG  +MD+I  T FG+ +DS  NP +PF+  A+KL +F  F+P+ + ++ FP ITPI+ +   N     + ++ FF   + K  + R    +++  DFL  MM AH    D +         ++L++ EIIAQS +F+ AGYETT+++L +  Y LA +P+ Q+++  EI          +Y+K+  + +L+  +NE+LR+ P  +R++RVC  DV +       +   KG +  VP++A+H DP+ WPEP +F   RF  E+K +   Y FMPFG GPRNC+GMRFA++ MK+AL  +L+ F   PC ET   +K  + A   P KPI+LK+V RS +I
Sbjct:   13 VLLAISLVLLYRLGTHKHDIFKKQGIPGPKPLPFLGTLLSYYK-GVWKFDIECRKKYGKIWGLFDGQTPLFSVTDTEMIKNVLVKECYSVFTNRRDFGPVG-IMSKAVSISKDEEWKRIRALLSPTFTSGKLKEMFPIIEQYGDILVKYLRREAEKGKPVITKEVFGAYSMDVITSTAFGVSVDSLNNPKDPFVEKARKLLRFDFFDPLFLSVVLFPFITPIYERL--NVSLFPKDSIEFFRKFVYKMKEHRLDYNQKHRVDFLQLMMNAHDNSKDKE-------SHKALSDMEIIAQSIIFIFAGYETTSSTLAFALYLLATHPDIQKKLQEEIDVALPNKTRPTYDKVMEMEYLDMVMNETLRLYPIGNRLERVCKRDVQM-----DGVFVPKGSIVMVPVFALHYDPQYWPEPEEFRPERFSKENKGSIDPYVFMPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQMPMKLSRKAMLQPEKPIVLKVVPRSAII 501          

Query:   64 LLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LI 1569
            +L  + + L+Y+LGT K ++ KK G  GP PLPF G      + G+++ DI  R KYGKI+  + G  P+  V+D E++K +L+K+    FT+R D G  G +  K + I K + W+R+R L+SPTFTSGKL++M P+++   D+L K L    E   P+  K+VFG  +MD+I  T FG+ +DS  NP +PF+  A+KL +F  F+P+ + ++ FP ITPI+ +   N     + ++ FF   + K  + R    +++  DFL  MM AH    D +         ++L++ EIIAQS +F+ AGYETT+++L +  Y LA +P+ Q+++  EI          +Y+K+  + +L+  +NE+LR+ P  +R++RVC  DV +       +   KG +  VP++A+H DP+ WPEP +F   RF  E+K +   Y FMPFG GPRNC+GMRFA++ MK+AL  +L+ F   PC ET   +K  + A   P KPI+LK+V RS +I
Sbjct:   13 VLLAISLVLLYRLGTHKHDIFKKQGIPGPKPLPFLGTLLSYYK-GVWKFDIECRKKYGKIWGLFDGQTPLFSVTDTEMIKNVLVKECYSVFTNRRDFGPVG-LMSKAVSISKDEEWKRIRALLSPTFTSGKLKEMFPIIEQYGDILVKYLRREAEKGKPVITKEVFGAYSMDVITSTAFGVSVDSLNNPKDPFVEKARKLLRFDFFDPLFLSVVLFPFITPIYERL--NVSLFPKDSIEFFRKFVYKMKEHRLDYNQKHRVDFLQLMMNAHDNSKDKE-------SHKALSDMEIIAQSIIFIFAGYETTSSTLAFALYLLATHPDIQKKLQEEIDVALPNKTRPTYDKVMEMEYLDMVMNETLRLYPIGNRLERVCKRDVQM-----DGVFVPKGSIVMVPVFALHYDPQYWPEPEEFRPERFSKENKGSIDPYVFMPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQMPMKLSRKAMLQPEKPIVLKVVPRSAII 501          

Query:   55 FKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKD-AKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLL----DKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            + LL+ FV + ++Y  G     + KKLG  GP PLPFFG F +  R G+ E D     KYGK++ FY G +PI  + D +++K +L+K+    FT+R + G NG I    + + +G+ W+R+R+++SPTFT+GKL++M P++K  ID+L    +K++A   +++ +++KD+FG  ++D+I  T FG+ IDS   PN+P +++ KKL  FS  +P+LILIL FP + PI  K   N   L ++ ++F V+   + + +RKKS  +   DFL ++M   + +N S  E+      ++LT  EI+AQ+  F+ AGYETT+T+L ++ Y LA +PE Q+++  EI          +Y+ I  + +L+  +NE+LR+ P   R++R+C +     T++   I   KG V  +P+Y +H DPE WPEP +F   RFD E +K+   Y F+PFG GPRNCVGMRFA+L +K ALV LL+ F + PC ET   ++ +   F  P KPIILK+V R
Sbjct:   12 WTLLVAFVTLLILY--GIWPYGIFKKLGIPGPRPLPFFGTFLEY-RKGILEFDKQCFQKYGKMWGFYDGRLPILAILDPDIIKIVLVKEFYTLFTNRRNFGLNG-ILDSGITVAEGEKWKRIRSIISPTFTTGKLKEMFPIIKHHIDVLVNNIEKKVA---QDESVNMKDIFGAYSLDVITSTSFGVDIDSINKPNDPLLVHIKKLLSFSFMSPLLILILVFPSLVPILEKM--NLSLLSKENIDFLVNASRRIIADRKKSNSRDRVDFL-QLMIDSQVMNGSRSEKRNN-SPKALTEMEIVAQAVTFIFAGYETTSTTLNFITYNLATHPEIQKKLLEEIDSTLPNKAVPTYDTIFQMEYLDMVVNETLRLFPLGGRIERICQK-----TAEINGITIPKGTVMLIPVYVLHHDPEYWPEPEEFRPERFDQEGRKSIDPYVFLPFGAGPRNCVGMRFALLTLKTALVTLLQNFTMEPCKETPIPLELETKGFMQPKKPIILKLVPR 502          

Query:   55 FKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSP-EQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAK---KGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS*LIDK 1575
            + LL+ F+ +  +Y  GT    + KKLG  GP PLPF G F+   R G+ + D+    KYGK++  Y G +P+  +++  L+K IL+K+    FT+R + G NG + +  + I K   W+R+R ++SPTFTSGKL++M P++K   + L + +    E  + +D+K +FG  + D++  T FG+++DS  NPN+PF+ N K+LF F   NPM+I+I+ FP + PI  K    ++   R  M+F+++ +N+  ++R+K   E   DFL  M+ +    N  +P+ +     ++LT++EI+AQS +F+LAGYETT+T+L+++AY LA +P+ QQ +  EI K        +Y+ +  + + +  +NE+LR+ PPA R++RVC   +        +IN +   +G V  +PI+ +H DPE WPEP +F+  RF  E+K+T+  YSF+PFG GPRNC+GMRFA+L MK+A+  LL+ F    C+ET   ++     F  P KP +LK+V RS  + K
Sbjct:   12 WTLLVVFLTLCFLY--GTWTHGVFKKLGVPGPKPLPFIGTFYHY-RKGMMDFDMECFKKYGKVWGIYDGRVPVLAITNTALIKSILVKECYTHFTNRRNFGLNGPL-EDSITIAKDDHWKRIRTVLSPTFTSGKLKEMFPIIKHFGETLVRNVHKKAEKGEALDMKQIFGAYSTDVVISTSFGVNVDSMNNPNDPFVTNGKRLFNFRFLNPMIIVIVLFPFLVPILAKM--KFQMFPRDLMHFYMNAVNRIKEKRQKGKHEDRVDFLQLMVDSQTAENIPEPDGMN-HGYKALTDAEIMAQSIIFILAGYETTSTALSFLAYCLATHPDVQQRLQEEIDKHLPNKATPTYDALMQMEYFDMVVNETLRMYPPAGRLERVCKNTI--------EINGQTIPEGMVTMIPIHVLHRDPEYWPEPEEFNPERFSKENKETQDPYSFLPFGTGPRNCIGMRFALLNMKVAITVLLQHFTFQTCSETPIPMELDTRGFIKPKKPNMLKLVPRSAAVPK 509          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKK-SPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            RHGL E D+    KYGK++  Y G  P+  + D  ++K I++K+    FT+R D G +G +   +LI  K + W+R+R ++SPTFTSGKL++M PLM    +LL K +   I   +P+D+K +FG+ +MD++  T F +++DS  NPN+PF+ NA+ LF FS FNP+ ++ +  P + P+  K   N+ FL  + +NFF   +     +R+K + E   DFL  M+ A      S PE+ E    + L+++EI+AQS +F++AGYETT+T+L ++AY +A +P+ Q+++  EI  +       +Y+ +  + +++  INESLR+ PPA R+DRVC +     T +   +    G V  VP++A+H++PEIWPEP +F   RF  E++K +  Y+F+PFG+GPRNC+GMRFA++ MK+AL  LL+ F L  C +T   +K     +  P KPIIL ++ +
Sbjct:   46 RHGLMEFDMECFKKYGKVWGIYEGQKPLLAIVDPVIIKSIMVKECYTNFTNRRDFGLSGPLKSSVLIS-KDEQWKRIRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNKEPLDMKHIFGSYSMDIVLSTSFSVNVDSMNNPNDPFVTNARNLFTFSFFNPLFLISILCPFLVPLLDKM--NFCFLSLKILNFFKDAVASIKKKRQKGTHEDRVDFLQLMVDAQSNEGKSVPEE-EKHGYKELSDTEILAQSLIFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEIDALLPNKAPPTYDALMKMEYMDMVINESLRMFPPAIRIDRVCKK-----TMEINGVTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLPFGVGPRNCIGMRFALVNMKVALTILLQNFRLETCKDTPVPLKICTKGYLKPTKPIILNLIPK 495          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERK-KSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            R G +  D+    KYGKI+  + G  P+  ++D+ ++K IL+K+    FT+R D+G NG++    L + K + W+R+RN +SP+FTSG+L++M  +MK   + L K L    +N+ I VKDVFG  +MD+I  T F + IDS  NP +PF+ N KK+      +P+ I+ + FP   P+  K      F  +   +FF+ +L K   ER+ K+ +   D L  M+ +  E +D   E+++    + L++ EI++QS  F+ AGYET++++L++  Y +A NPE  +++ REI + F     ++Y+ + N+ +LEAA+NES+R+ P  +R++RVC E + +       +   +G    +P++ +H DPE W +P  F+  RF   +K+    Y +MPFG GPRNC+GMRFA+L MK+A+V +L++F+++        +K     F  P  PI LK + R+
Sbjct:   54 RKGFHAFDMECYRKYGKIWGIFDGREPVLSIADQTIVKSILVKECYTYFTNRRDVGLNGEL-YDALFVTKDEDWKRIRNHLSPSFTSGRLKEMFGIMKTHTNTLVKNLEKSRKNEGIAVKDVFGAYSMDVITSTAFSVDIDSMNNPKDPFVTNIKKMLDIDFLSPIFIVAMVFPFALPLLEKM--KISFFSQSVSDFFLGSLKKIKTEREAKNHKSRVDILQLMVDSQTE-DDQQGEEMK----KGLSDHEILSQSMSFIFAGYETSSSTLSFFFYNIATNPETMKKLQREIDQTFPNKTPVNYDAVMNMEYLEAALNESMRLFPVVARLERVCKETIEI-----NGLTIPQGTSIMIPVFPLHRDPEYWSDPSTFNPERFTKGNKENVDPYVYMPFGSGPRNCIGMRFALLAMKLAIVEILQRFDVINPDPNQVPLKLGIHPFLSPKYPIKLKFIPRA 499          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDS---RSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            + G    D+    KYGK++  Y    P+  + D E+LK ILIK+    FT+R +   NG +   + II +   W+R+R+++SP+FTSG+L++M  +MK     L + L    +  +  D+K++FG  +MD++  T F + IDS  NP++PF+ N KK+ KF   NP+ + +  FP I P+  K   N+ F     M+FF + L K   +R  S  +   DFL  M+ + K       E++E  D      LT+ EI++QS +F+ AGYETT+++L++  Y +A NPE  +++ +EI + F  +  I Y+ + N+ +L+AA++ESLR+ PPA+R++RVC + V +      ++   +  V   P++ +H DPE WPEP  F   RF   +K+    + +MPFG GPRNC+GMRFA++ +K+A+V +L++F+++   ET   ++   +    P  PI LK + R
Sbjct:   54 KQGFQNFDLECFKKYGKVWGIYDARQPVLCIMDREILKTILIKECYSLFTNRRNFRLNGPLYDAVSII-EDDDWKRIRSVLSPSFTSGRLKEMFGIMKTHSHTLVQNLGKTSKRGEAADIKEIFGAYSMDVVTSTAFSVDIDSLNNPDDPFVTNIKKMLKFDFLNPLFVAVALFPFIAPVLEKM--NFCFFPPAVMDFFYAALKKIKSQRVSSDNKKRVDFLQLMIDSQKS------EKVEHHDKGAIHGLTDHEILSQSMIFIFAGYETTSSTLSFFFYNIATNPETMKKLQQEIDQTFPNESLIQYDAVMNMDYLDAALSESLRLYPPAARLERVCKKTVEI-----NRLTIPQNTVVLAPVFPLHRDPEYWPEPDTFKPERFTKGNKENIDPFVYMPFGSGPRNCIGMRFALVTIKLAIVEILQRFDVILSEETKVPLELGISGLLAPKDPIKLKFIPR 501          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKC-FTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEN-DPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERK-KSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            R G +  D+    KYGKI+ F+ G   +  + D+ ++K IL+K+    FT+R D G NG++    L I K + W+R+RN +SP+FTSG+L++M  +++   + L K L    +N + + VK+VFG  +MD+I  T F + IDS  NP++PF+ N KKL  F +F+P+ +L   FP + P+  K    +        +FF  +L K   ERK K+ +   D L  M+ +  E      E       + LT+ EI++QS +F+ AGYET++++L++  Y +A NPE  +++ +EI + F  +  + Y+ + N+ +L+AA+NES+R+ P  +R++RVC E + +       +   +G    +P++ +H DPE WP+P  F+  RF   +K+    Y +MPFG GPRNC+GMRFA L MK+A+V +L++F ++        +K     F  P  PI LK   R+
Sbjct:   54 RKGFHVFDMECYRKYGKIWGFFEGRDRVLCIVDKSIVKSILVKECYTYFTNRRDFGLNGEL-YDALFITKDEDWKRIRNHLSPSFTSGRLKEMFGIIQTHANTLVKNLEKSSKNTEGVAVKEVFGAYSMDVITSTAFSVDIDSMNNPDDPFVTNIKKLLDFDVFSPLFLLAGLFPFLIPLLEKM--KFSIFPAAVADFFFVSLKKIKAERKAKNHKSRVDILQLMVDSQTEGEQQGEEM-----KKGLTDHEILSQSMIFIFAGYETSSSTLSFFFYNIATNPETMKKLQQEIDQTFPNNAPVQYDAVMNMEYLDAALNESMRLFPSVARLERVCKETIEI-----NGLTIPQGTSIMIPVFPLHRDPEYWPDPSTFNPERFTKGNKENIDPYVYMPFGSGPRNCIGMRFAQLAMKLAIVEILQRFNVINPDPDQVPLKLGTNIFLAPKDPIKLKFPPRA 500          

Query:   67 LCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSN--GKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPE-QLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            L  +VI L+Y  G       KKLG  GP P PFFG F    + G Y+ D     KYGK++  + G +PI +VSD E++K I++KD    FT+R +   +  G     + I+ K + W+R+R  VSP FTSGKL+++ P+ +   D   + L     + P+ VKDVF   +MD++A   F + IDS  NP++PF  + KK F FS F+P+ + ++ FP    I  K    +    +  M FF ++L K  D+      +  DF+  M++   +++D   E   E    + LT+ EI++QSF+F+L GYETT+T+LT++ Y LA NP+   ++ +EI ++F     ++Y+ +  L +LE  INES+R+ P A R++RVC + V L       I   K  + T+P Y +H DP++W  P +F   RF  E+      Y FMPFG+GPRNCVGMRFA++ MK+ +V LL+ F +  C ET   I  +      P  P+ LK   R+
Sbjct:   13 LVVLVITLLYIYGVWPYGFFKKLGIPGPKPWPFFGTFLSYTK-GFYKFDTECYKKYGKVWGIFDGRLPILMVSDYEMIKSIMVKDCYSVFTNRRETNKDLAGPFADGISIV-KDEKWKRIRASVSPFFTSGKLKEIFPIAEKYGDRFIENLKKRSPDGPVKVKDVFAPFSMDVVASASFSVDIDSINNPDDPFGAHIKKFFNFSFFSPLFLFLVLFPSAAGILGKM--GFSMFAKSDMEFFYTSLKKLKDQHNNMNHKRVDFMQLMIQG--QISDHQAESSSEEQPIKGLTDHEILSQSFIFMLGGYETTSTTLTFLLYNLATNPDCLNKLMKEIDEMFPHGAPVTYDALMKLEYLEMVINESMRLFPTAPRLERVCKKTVEL-----NGITIPKDTLVTIPAYVLHRDPQLWESPEEFRPERFSPEN--NIDPYLFMPFGLGPRNCVGMRFALMIMKLVVVKLLQNFNVETCKETQ--IPLQLDTLFRPKVPVTLKFTPRA 499          

Query:   67 LCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSN--GKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPE-QLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            L  +VI L+Y  G       KKLG  GP P PFFG F   I+ G    D     KYGK++  Y G +PI +V D E++K I++KD    FT+R ++     G     + ++ K + W R+R  +SP FTSG+L+++ P+ +   D   + L     + P+ VKDVF   +MD++A   F + IDS  NP++PF  + KK F FS F+P+ + ++ FP    I  K    +    +  M FF ++L K  D+      +  DF+  M++   +++D   E   E    + LT+ EI++QSF+F+L GYETT+T+LT++ Y LA NP+   ++ +EI ++F     ++Y+ +  L +LE  INES+R+ P A R++RVC + V L       I   K  + T+P Y +H DP++W  P +F   RF  E+   R  Y FMPFG+GPRNCVGMRFA + MK+ +V LL+ F +  C ET   I+   T F  P  P+ LK   R+
Sbjct:   13 LVVLVITLLYIYGVWPHGFFKKLGIPGPRPWPFFGTFLSYIK-GFQNFDTECYKKYGKVWGIYDGRLPILMVLDHEMIKSIMVKDCYSVFTNRREMNKELVGPFSDGITVV-KDEKWRRIRGSLSPFFTSGRLKEIFPIAEKYGDRFIENLKKRSPDGPVKVKDVFAPFSMDVVASASFSVDIDSINNPDDPFGAHIKKFFNFSFFSPLFLFLVLFPSAAGILGKM--GFSMFAKSDMEFFYTSLKKLKDQHNNMNHKRVDFMQLMIQG--QISDHQAESSSEEQPIKGLTDHEILSQSFIFMLGGYETTSTTLTFLLYNLATNPDCLNKLMKEIDEMFPHGAPVTYDALMKLEYLEMVINESMRLFPTAPRLERVCKKTVEL-----NGITIPKDTLVTIPAYVLHRDPQLWESPEEFRPERFSPENNIDR--YLFMPFGLGPRNCVGMRFAQMIMKLVVVKLLQNFSVETCKETQIPIQL-DTLF-RPTVPVTLKFTPRA 499          

Query:  196 GLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDV-FGTLTMDMIA--RTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFP-EITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN---DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            G  E D  +  KYG+++  Y G +P+ +V+D  +LKQIL+KD  + FT+R   G +G I + +L+I + + W+R+RN+++P F+ GK+++M PL++ C ++L + L    +   P+D+KD  FG+  +D +      FG  +  +  P++P +  A K      F+P+  +ILFFP  I+P+ R          ++ ++FF   + +  ++R+K         DFL +M+ A    N S+        +  LT+ E+ +Q+ LFL+AGY+ T+TS+T++AY LA NP+ Q +V +EI  +    +   YE +  + +L+  + E+LR+   +SR DRVC +  V+       +   KG V TVP++ +H DP+ W EP++F   RF  E+K+ R  Y ++PFG GPRNC+GMRFA++ +K+A+  +L+++    C+ET    +F K  F    KP+ +K+V R
Sbjct:   56 GFREFDAESFRKYGRVWGIYDGRVPVLMVTDTNMLKQILVKDCLESFTNRRKFGLSGPI-KDVLLIAEDEHWKRIRNVLTPAFSGGKIKQMCPLIQRCAEVLVQNLHEPCQLEQPVDLKDEKFGSGILDHLEFEGEGFGEIVKQKVFPHDP-VPKALKYIFLCEFSPLFAVILFFPFLISPLERL---GVTLFDKKAIHFFHKIVQQMKNKRQKGLNDMQGRVDFLQQMVNAQLSENTSN-------GNEDLTDGELESQAVLFLMAGYDNTSTSITFLAYCLACNPDVQTKVQQEIDTILPDGKLPDYETLKQMEYLDMVVCETLRMYSSSSRTDRVCKKTTVV-----NDLVIPKGVVVTVPLWVLHYDPQYWDEPHEFRPERFTKEAKEARDPYCYLPFGHGPRNCIGMRFALMSVKIAVCRILQRYSFQTCSETTIPPQFNKNTFLQLEKPLKVKVVAR 501          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDP-IDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLG-----RQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAH---KEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
              G  E D  +  KYG+I+  Y G +P+ +V+D  +LK +L+KD+ + FT+R +IG NG   + M I    + W+R+RN++SPTF+ GK+++M PL+  C D L K L    ++   +D+K++  +  + +         I    N            F       M++        TPIF +  P  EFLG     ++  +FF + + ++    KK+ +   DFL  M+         N ++P        + LT+SE+ AQ+ LFLLAGYETT+T++T+VAY LA NP+ Q +V +EI +    D   SYE +  + +L+  ++E+LR+ PP SR DRVC +  V+       +   KG V TVP++ +H DP+ W EP +F   RF  E+K+ R  Y ++PFG GPRNC+GMRFA++ MK+ +  +L+++    C ET    K  K  F     P+++++ +R
Sbjct:   49 HQGFKEFDQNSFKKYGRIWGTYDGRLPLLVVADTSILKTVLVKDSLEFFTNRRNIGLNGPFKEAMSIA-NDEKWKRIRNVLSPTFSGGKIKQMCPLIVRCADSLVKNLREKCQSGKLVDLKELHVSCKLRISLPKSLCALIGKYGN------------FTSDTSRQMVLCFTGINLTTPIFPELVPPLEFLGLSFFPKKASSFFTTIVRQSDVNIKKNNKGRVDFLQLMVDVQLSKSMQNGANPH-----SDKYLTDSELEAQAILFLLAGYETTSTAITFVAYCLACNPDVQTKVQQEIDRFLPNDTLPSYEILKQMEYLDMVVSETLRMYPPTSRTDRVCKKTTVV-----NDLVIPKGVVVTVPLWVLHYDPQYWDEPEEFRPERFSKEAKEARDPYCYLPFGQGPRNCIGMRFALMSMKIVVCRILQRYSFHACNETTIPPKLTKNPFLQLENPLLVQVSER 491          

Query:  196 GLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRL-AGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLG-----RQTMNFFVSNLNK-----AMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            G    D  +  +YG+++  Y G +P+ +V+D  +LKQIL+KD  + FT+   IG N   G+  L  +  + W+R+RN++SPTF+SGK+++M PL+  C D+L K L         +D+K   G   ++    T + + I     P  P +++  K+   +++N           ++ +F  F P +E++G     ++   FF + + +     +M+   K    +   + +   +    N ++P        + LT+SE+ AQ+ LFLLAG+ETT+T++T+VAY LA NP+ Q +V +EI +    D+  SYE ++ + +L+  ++E++R+ PPA+R+DRVC       T DN  I   K  V TV  + +H DP+ W EP +F   RF  E+K+ R  Y ++PFG GPRNC+GMRFA++ +K+A+  +L+++    C+ET    K  K +     KP++LK+ +R
Sbjct:   56 GFRAFDEESFQRYGRVWGIYDGRLPVLMVADTNMLKQILVKDCLEFFTNHRKIGLNELFGEG-LSTVDDEQWKRIRNILSPTFSSGKIKQMYPLILRCADVLVKNLHEKCQSGKSVDLKQGNGEWRLETNRVTAYKIFIALVKRPPPPLLLSRSKMININIYNVQRF------SLSALFPVFVPLFEYMGLSLFPKKICIFFKNIVQQFKTDISMNYSTKGRVDFLQLMVDAQLSETVQNGANPH-----SEKYLTDSELEAQAILFLLAGFETTSTAITFVAYCLACNPDVQTKVQQEIDEFLPDDKAPSYEILNEMEYLDMVVSETMRMYPPAARLDRVCKRTT---TVDNLVI--PKDVVITVSTWVLHYDPQHWEEPNEFRPERFTKEAKEARDPYCYLPFGQGPRNCIGMRFALMSVKIAVCRILQRYSFQMCSETTIPPKLAKGSILQTEKPLLLKVSER 504          

Query:  697 LFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSD-PEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            +FFP +TP+  +   N     +  ++FF+SNL +   ER+K       DFL  M+ A  +++DS   E   I+  ++LT+SEI++Q+ +FLLAGYETTA +LTY+AY LA + + Q ++  EI      +    Y  +     L   ++ESLR+ PPA R++R+   DV L       I   KG V  +P++ IH   E W +P  F   RF  E+++ R  Y ++PFG GPRNC+GMRFA++ +K+A+V+LL++F  V C ET    +        P +PIILK  +R+
Sbjct:    2 VFFPAVTPLLVRM--NVSMFPKDVLSFFMSNLQRLKSERRKGEHTDRVDFLQTMVDA--QISDSVMDEHGGIIPYKALTDSEILSQAMVFLLAGYETTAVTLTYIAYNLAVHVDVQDKLLEEIDATLPPEAPYCYRIL-----LPHVVSESLRLYPPAGRLERIAKMDVEL-----GGIPVPKGTVIGIPVFVIHRHSEHWDDPTAFRPERFSKEAREQRDQYCYLPFGAGPRNCIGMRFALINVKIAIVSLLRRFTFVTCPETKIPAEIGIRGLLEPKEPIILKFAERN 277          

Query:  382 LIILKGKSWERVRNLVSPTFTSGKLRK-MSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDM---IARTMFGMHIDSQTNPNNPFI--------INAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLN--KAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFEL 1464
            L++L G  W R R L++P F    L+  ++ + +    +LDK    + E  P    +VFG +++ M   I +  F    + QT   N ++        +  ++   F+L N  +  +      TP  R+F        + T +         K   ++ K+ ++ N DFL  ++ +               D +SL++ EI  +    + AG++TTA+ L++V + LA NP  Q+    E  +V     +  ++ ISNLP+    I ESLR+ PP   + R  T+ + L            G    V I+ IH + E W +P  FD  RF  E+   R  Y+F+PF  GPRNC+   FA+ E+++ +  +L +F +
Sbjct:  122 LLVLSGPKWFRNRRLLTPGFHYEILKPYIAIIGQSTASMLDK-WERLTEKQP--TLEVFGDISLLMLHSILKCAFSYEGNCQTEAGNSYVRAVYELTDLVHRRFRNFALHNKWVYYL------TPAGRRFQKAKGHAHKHTEDVIRRRRETLKLEAQQDKTQQKRNLDFLDILLSSRDA------------DGQSLSDEEIRTEVDTIMFAGHDTTASGLSWVLHALASNPHHQEVCRDEAARVLAGRSQPEWDDISNLPYTTMVIKESLRLYPPVPSIIRKLTQPLKLPHGHV----LPAGMRVCVSIFCIHRNEEFWKDPEVFDPLRFSQENSAHRHPYAFIPFSAGPRNCIDQNFALNELRVTVAMILSRFRI 472          

Query:  199 LYELDII-NRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKML--------IILKGKSWERVRNLVS---PTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPF---IINAKKLFKFSLFNPMLILILFFPEITPI------FRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIW--------PEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKI 1548
            LY+L I  + +KYG +  F+FG     +VS  E L QI  KD   F      G+  KI    L        I   G  W   RN V+     F    + K + ++  C  + ++ L G      I +  +   + +D I++   G    + T+  N F   +I  KK     +F+P  +   F  ++ PI      F+      E L ++  +  V+N            EQ     +++++AH           EI+D + LT++ +I      L+AG+E          Y LAK     QE  R+  +V G  +    + +++LP L A + E +R+ PP S +   CT     + +   +I   KG       +    DP+ W        PE +  D+       +  ++  +   F  G R C+G + A+ EM+++L  +LKQF       +LD    +K    GP+ P+ LK+
Sbjct:   54 LYDLYIRESMEKYGAV-KFFFGSRWNILVSRSEYLAQIF-KDEDTFAKS---GNQKKIPYSALAAYTGDNVISAYGAVWRNYRNAVTNGLQHFDDAPIFKNAKIL--CTLIKNRLLEG---QTSIPMGPLSQRMALDNISQVALGFDFGALTHEKNAFHEHLIRIKK----QIFHPFFLTFPFL-DVLPIPSRKKAFKDVVSFRELLVKRVQDELVNNYKF---------EQTTFAASDLIRAHNN---------EIIDYKQLTDNIVI-----ILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRK--EVNGITDP---KGLADLPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGA---EIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRW-----SLDPEWEEKLTPAGPLCPLNLKL 481          

Query:  910 DSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVF-GTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSI-----YSF-----------MPFGMGPRNCVGMRFAVLEMKMAL 1437
            D   +T+ EI       L+ G  T+A +  ++   LA+ P+ QQE+Y E ++V  G  +E++Y+ +  +P L   I E+LR+  P   + R   +D  +   +   +      V   P Y  H+  E +P  ++F++ R++ +S  + S+     Y F           +PFG G   C+G  FA  ++ + +
Sbjct:  295 DGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKD--MHVPNTSYVIPAGYHVLVSPGYT-HLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLM 484          

Query:  703 FPEITPIFRKFFPNWEFLGRQT----MNFFVSNLNKAMDE--RKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTD--EEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVG-----MRFAVLEMKMALVNLLKQFELVPCAETLDV 1491
            FP I P  + ++      G++T    M  F +    A D       P    D   ++M   K  ND D      +  R  TN EI    F FL A  + +++   ++   +A  P+   ++  E + V   D   E++ + I  + +    I E+LR  PP   V  V  ++  +    +    A KG +    +Y    DPE++  P +F   R+   SK + +  +++ FG GP  C+G     + FA L  K AL        + P +E + V
Sbjct:  252 FPIIIPYTKTWY------GKKTADMAMKIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSR----IYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPV----SPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHH-TVTPLSEKIKV 512          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGS-NGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKD-CIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKF-SLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMN-----FFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGT-DEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            +H  Y  + + +  YG++  +Y G     +V+D E+ KQIL+K+   F +R  + S       K L+ L+   W R+R+ ++PTF++ KL+++ PL+ + C  L++K      +   +DV   +G  TM+ I  T FG+   +QTNPN+ F+ NA++LF   SLF    +L + FP + PI          LG+QT       F V    + +  R+++  Q    L E++ +  E  D D  +        L++ EI+AQ F F+LAGYETT+ ++ + +Y LA NP+ Q  +  EI +V  T  +   Y+ +  + +LE  + E+LR+ PP  R  R C +   +    N Q    KG +  +P++A+H DPEIWPEP KF   RF  E+K+ R  Y+ +PFG GPRNC+GMRFA+LE KMALV +L+ + L  C ET   ++ + T    P   I LKI KR
Sbjct:   64 KHDTYAQEYLVK-TYGRLCGYYMGTRAAILVADPEMAKQILVKEFDKFVNRPIVQSAQTPPTDKTLLSLQDDDWRRLRHTITPTFSAVKLKQVLPLINESCRILVEKLGEACKDGKSVDVLRSYGKFTMETIVTTAFGIDCQTQTNPNDQFVPNAQRLFGGQSLFR---MLAVLFPYLQPIVSLMVKQLG-LGKQTETGKSAMFIVDAARQIIKHRRETGSQGRKDLLEILLS-AETTDDDGRR-----KNKLSDDEIVAQCFTFILAGYETTSNTMAFTSYLLALNPDKQDRLIEEIDEVAATVGDNFDYDTVLGMEYLEMVVQEALRLYPPGFRFGRTCNQSCTI----NGQF-FPKGCIVLIPVFAMHRDPEIWPEPEKFQPERFTAEAKQARHPYAHLPFGGGPRNCIGMRFALLEAKMALVYILRYYRLERCPETEVPVQLQGTITISPKHGIYLKITKR 512          

Query:  181 DIIRHGLYELDIIN--RDKYGKIYP-FYFGGIPISIVSDEELLKQILIKDAKCFTDRLD-IGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGT-LTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFP-----NWEFLGRQTMNFFVSNLNKAMDERKKS--PEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEI-SYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAET 1482
            D+IRH    L      R KYG++Y  F  G  P  +V+D E++K I++K+   F DR   +    +    M+   K + W R+RN +SP F++ K++ M PL+    D+L  +L  + E+        F   LTMD I +T FG+  ++QTN ++P    A+K    S    +++ +LF         K FP     N+E L   T         K + E KKS    +  D L  M+ A    N S          + L++ E++AQS +FL+AGYETT  +L++VAY LA NPE Q+++ REI  V+  ++E+ SY+ + NLP+L+  I+E+LR+ PP     R CT+D V+     K    +KG    +  Y++H DPE W +P +FD  RF +E+ ++R  YS++PFG GP NCVGMRFA +EMK+ALV +LK+F  V  A+T
Sbjct:   22 DLIRHKGQILKQFQEYRKKYGRLYAMFLVGKKPCVVVADPEIVKHIMVKEFSSFRDRPSFVMEQPEPFDSMMTSAKYEKWHRIRNTLSPAFSAHKMKLMVPLINSSCDVLINKLTKVAESGESFFTHKFHQGLTMDTILKTAFGIQSEAQTNYDDPAFKAARKSLSTSTTRRVIVTLLFLMPFKNYIFKAFPSLVIGNFEGLLEMT---------KMIVEVKKSNLHNEAKDMLDLMLSAAANENTS----------KKLSDMEVLAQSLIFLIAGYETTNITLSFVAYSLATNPEVQEKLQREIDSVWTEEDEMPSYDTVHNLPYLDMVISETLRLYPPGFVASRECTQDCVI-----KGYRFRKGLPIFIDAYSMHHDPEFWTDPERFDPERFSSEANQSRDPYSYLPFGHGPHNCVGMRFAQMEMKLALVRVLKKFSYVATADT 444          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDR------LDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLA-GIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQT-----MNFFVSNLNKAMDERKK----------------SPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGT-DEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            +H  Y  + + +  YG++  +Y G     +V+D E+ +QIL+K+   F +R      L + S+     K LI L+   W R+R+ V+PTF++ K++++ PL+ +   +L ++L     +   +DV   +   TM+ I  T FG+   +QTNPN+ F+ NA++ F     +P  IL + FP + PI          LGRQT     + F V    + +  R++                S  +  D L  ++ A  E  D D ++        L++ EI+AQ F F+LAG++ T+ ++ + +Y LA NP+ Q  +  EI  V  T  +   Y+ +  + +L+  + E+LR+ PP  R+ R C +   +    N Q    KG +  +P+YAIH DPEIWPEP KF   RF  E+K+ R  Y+++PFG GPRNC+GMRFA+L++KMALV +L+ + L  C ET   ++ +      P   + L+I KR
Sbjct:   31 KHDTYAQEYLVK-TYGRLCGYYRGTRASILVADPEMAQQILVKEFDKFVNRGVSEGLLPLSSHIPPTDKNLISLQDDDWRRLRHFVTPTFSAVKIKQVVPLISESCRILVEQLGQACKDGKSVDVCRTYVKFTMETIVSTAFGIDCQTQTNPNDQFLSNAQRYFGKP--SPFTILAVLFPYLQPIISVMVRRLG-LGRQTEIGKSVMFIVDAARQIIKHRRETGSKGVKYLHFPQGEPSGPRKKDLLEILLSA--ETTDDDGKR-----KNKLSDDEIVAQCFTFILAGFQNTSNTMAFTSYLLALNPDKQDRLIEEIDDVAATVGDNFDYDTVLGMEYLDMVVQEALRLYPPGFRLGRTCNQSCTI----NGQF-FPKGCLVMIPVYAIHRDPEIWPEPEKFQPERFTAEAKQARHPYAYLPFGEGPRNCIGMRFALLKVKMALVYILRHYRLERCPETEVPLQLQGFISMSPKHGMHLRITKR 499          

Query:   43 YFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIR-HGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDI--GSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISN-LPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAET 1482
            YF    L+L  +V+ +IY +G     + K L   GP PLP+ GN  DI R  G++   +    +YGK++ +  G  P  +V D E+LK +++K+ + F +R  +   +  ++   M      K W+R+R+ ++PTFTSGKLR+M+P +++  D L  ++  + +  + +D+  +F  +T+++I  T FG+  + Q NPNN F   AK++FK   F  M +++ F      IFR    N        M +F+    + + +R        DF+  M+ A       +P+      SR L++ EIIAQS  FLLAG+ET++ +L+  AY+LA NPE Q+ +  EI     T+ + S  +++N L +L+  +NE LR+ PP   ++R C +  V+       I    G   T+P Y++H DP+ WPEP KFD  RF   +K++R  + F+PFG GPRNC+GMRFA+ E+K+ L  +L +++ V   +T
Sbjct:   13 YFLAGTLIL-LIVLAVIYWVGVSSFRVLKGLNIPGPTPLPYIGNLRDIQRLGGIHVAPVRLMQEYGKVFAWSVGRTPAIVVGDPEILKHVMVKEFQNFRNRFLLFRDTRSEMLHGMFSATDDK-WKRIRSTLTPTFTSGKLRQMNPKIRESCDTLMDKIGKVADTGESVDILGMFCQMTLEVILSTAFGIDSEVQKNPNNTFSDKAKEIFKSPTFLRMFLMLPFASVFFKIFRFLIHN------NNMKYFIDLSKEILSKRHDKTFNRKDFVDLMLSA------VNPD-----GSRKLSDPEIIAQSVTFLLAGHETSSNALSATAYYLALNPEVQERLRLEIRMAAETNSDKSPHELANDLEYLDCVVNEVLRLHPPVHTMNRECAQACVI-----NGITIPAGMDVTIPFYSLHHDPDAWPEPDKFDPERFRGPAKESRHPFQFIPFGAGPRNCIGMRFALNEVKLVLFQILSKYKFVRSPDT 473          

Query:  208 LDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPE-NDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPML---ILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEI-SYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAET--LDVIKFKKTAFGGPVKPIILKIVKR 1557
            LD   +   G      F G P  +V D  LLK I++K+  CF DRL    +  +  KML IL G+ W  +R+ +SP F++ KL+ M PLM    D+  K++A   E  + IDV  +   LT+D+I    FG+  D Q NP +P +  A    + SL   +L   +L L       +  K   +  F     +N FV  +   +  +K+      D L  M++A    N            ++L+   IIA + +FLLAG+ETT++++ + +YFLAKNP+ Q+++ +EI  V+  +EE+ SY+ + +LP+LE  I+E+LR+CPP   V R CT+  ++      ++   +G      +Y+IH DP+ +P+P  FD  RF  E K +R  Y++MPFG GP NC+GMRFA +E+K+ LV +LK++ L    +T  L++I  +      PVK   L +V+R
Sbjct:   74 LDEFYKQYEGPAIRLSFMGKPSILVKDTALLKAIMVKNFDCFHDRLKADFSPPL-DKMLTILPGEEWRNLRHALSPNFSAHKLKGMVPLMNKACDVYMKKIACAAETGETIDVMKINPALTLDIIISCAFGVESDCQNNPKDPVMKKATAAMRPSLIRTILANAVLPLLPGGQKLVSSKIGASLFFREVLELNSFVQGV---IQMKKREGSSRKDMLDLMLEAAASDNTDG--------GKALSLDAIIANTIVFLLAGHETTSSTIAFASYFLAKNPKIQEKLQQEIDSVWSGEEEMPSYDTVHDLPYLEMVISETLRLCPPGFAVIRECTKTCII-----NKLRIPQGSRVLASVYSIHRDPKYYPDPDIFDPERFSPEGKASRDPYAYMPFGHGPHNCIGMRFAQMEIKLVLVRMLKRYTLCVTQDTKPLNIISNQTLTTNEPVK---LGVVRR 510          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKD-CIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            R G    D   R KYGK +  Y G  P+  ++D   +K +L+K+    FT+R +   NG +   +    +   W+R+R+++SP+FTSG+L++M  +MK    +L++       +++P+++KD FG  +MD++  T F + IDS  NP++PF+ N KK+ KF   NP+ +L+ FFP + PI  K      F      +FF S L K   + K + ++   DFL  M+ + K   +        L  + L++ EI++Q+ +F+ AGYETT++SLT++AY LA NPE  +++ +EI   F     I Y  +  + +L++ +NESLR+ P A+R++RV        T +   +   K  V  VP + I  DPE+WPEP KF   RF  E+K+T   Y++MPFG GPRNC+GMRFA++ MK+ALV +L+Q+    C ET    +        P +PI LK+V RS
Sbjct:   54 RKGFPIFDEECRKKYGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFHLNGPMYDSVFNA-EDDQWKRIRSVLSPSFTSGRLKEMFDIMKHHSANLVNSMKKKADKDEPLNLKDHFGPYSMDVVTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLLVAFFPFLGPIMEKM--ELSFFPASAFDFFYSALQKIKSDHKNNKQKSRIDFLQLMIDSQKNNQNG-------LQDKGLSDHEILSQAMIFIFAGYETTSSSLTFLAYNLATNPEVMKKLQKEIDATFPNKAPIQYAPLLEMEYLDSVVNESLRLYPIAARLERVAK-----ATVEVNGLVIPKDMVVMVPTWPIQRDPELWPEPEKFKPERFSKENKETFDPYTYMPFGAGPRNCIGMRFALVSMKLALVEILQQYSFSVCKETEIPFELDIQGLIAPKRPIFLKLVPRS 498          

Query:  190 RHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKD-CIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            R G +  D   R KYGK +  Y G  P+  ++D   +K +L+K+    FT+R +   NG +    + I +   W+R+R+++SP+FTSG+L++M  +MK    +L+      + +++P+++K+ FG  +MD++  T F + IDS  NP++PF+ N KK+ KF   NP+ + + FFP + PI  KF   +       M+FF + L K     + + ++   DFL  M+ + K   +        L  + L++ EI++Q+ +F+ AGYETT++SLT++AY LA NPE  +++ +EI   F     + Y  +  + +L+  +NESLR+ P A+R++RV        T +   +   K  V  VP + +H DPE+WPEP KF   RF  E+K T   Y++MPFG GPRNC+GMRFA++ MK+A+V +L+ ++   C ET    +     F  P +PI LK+  RS
Sbjct:   54 RKGFFNFDEECRKKYGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGPL-YDAVSIAEDDQWKRIRSVLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMKEYFGPYSMDVVTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVAFFPFLGPILEKF--EFSLFPSSVMDFFFAALRKIKANHENNKQKSRIDFLQLMIDSQKNNQNG-------LQDKGLSDHEILSQAMIFIFAGYETTSSSLTFLAYNLATNPEVMKKLQKEIDATFPNKAPVQYVPLMEMEYLDCVVNESLRLYPIAARLERVAK-----ATVEVNGLVIPKDMVVMVPTWPLHRDPELWPEPEKFKPERFSKENKDTFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSVCKETEVPFEMDVQGFLAPKRPIQLKLTPRS 498          

Query:  184 IIRHGLYEL--DIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPEN-DPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTM-NFFVSNLNKAMDERKKSP--EQYNDFLTEMMKAH------------------------------KEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            + R G ++   D+I    +G++  +Y G  P+ +++D +LL+Q+++KD   F +R+ +    K     L+ LK + W RVR++++P+F++ K+++M PL+    ++L K L    E+    D+   FG  TMD+IA   F   +DSQ  P++PF+ +A+  F FS F PM++  + FP +     +F PN     R  M NFF+ N+ K + +R++ P  ++  DFL  M+ A                               +E + S+   L     + +T  E++ Q+F+FLLAGYETT+++L +  Y LA +PE Q +V +E+ + F   E   Y  I  L +++  ++E+LR+ PP  R  R   ED V+       +   KG    +P   +H DPE W EP KF   RF  E+K +R  + ++PFG GPRNCVGMR A LE+KMAL +L + F +V C+ET   ++ K ++  GP   I +KI KR
Sbjct:   62 LFREGFFKPLNDLIK--THGRVCGYYLGRKPVVVIADPDLLRQVMVKDFSSFPNRMTLRFATKPMVDCLLALKDERWRRVRSILTPSFSAAKMKEMVPLINTVTEVLMKNLTTHAESGQAFDIHRCFGFFTMDVIASVAFATQVDSQNKPDDPFVHHAQMFFTFSFFRPMMMFFIAFPSLMAPVARFIPNKR---RDEMSNFFIHNIQKIIKQREEQPPDQRRRDFLQLMLDARTAKECASLDQFDTSNHGDETLTNPKAASSDQESSRSEESALRRPQKKMMTEDEVVGQAFIFLLAGYETTSSTLGFTCYLLAVHPECQHKVQQEVDQFFSRHESPDYTNIQELKYMDMVVSETLRLYPPGFRFAREVEEDCVV-----NGVRLPKGATLEIPAGFLHYDPEYWSEPEKFIPERFTAEAKASRHPFVYLPFGSGPRNCVGMRLAQLEIKMALAHLFRSFSVVACSETKVPLELKSSSTLGPKNGIFVKITKR 545          

Query:   55 FKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKD-CIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYN-DFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            + LL+ F+ + L+Y          K+LG  GP P+PFFG      R G +  D   R KYGK +  Y G  P+  ++D   +K +L+K+    FT+R +   NG +    + I +   W+R+R+++SP+FTSG+L++M  +MK    +L+      + +++P+++K+ FG  +MD++  T F + IDS  NP++PF+ N KK+ KF   NP+ + + FFP + PI  KF   +       M+FF + L K     + + ++   DFL  M+ + K   +        L  + L++ EI++Q+ +F+ AGYETT++SLT++AY LA NPE  +++ +EI   F     + Y  +  + +L+  +NESLR+ P A+R++RV        T +   +   K  V  VP + +H DPE+WPEP KF   RF  E+K T   Y++MPFG GPRNC+GMRFA++ MK+A+V +L+ ++   C ET    +  K  F  P +PI LK+  RS
Sbjct:   12 WTLLVAFITLLLVY--AYWPYGTFKRLGIPGPKPVPFFGTML-AYRKGFFNFDEECRKKYGKTWGIYDGRQPVLCITDPATIKAVLVKECYSLFTNRRNFRLNGPL-YDAVSIAEDDQWKRIRSVLSPSFTSGRLKEMFDIMKHHSANLIQSMKKKVDKDEPLEMKEYFGPYSMDVVTSTAFSVDIDSLNNPSDPFVTNIKKMLKFDFLNPLFLAVAFFPFLGPILEKF--EFSLFPSSVMDFFFAALRKIKANHENNKQKSRIDFLQLMIDSQKNNQNG-------LQDKGLSDHEILSQAMIFIFAGYETTSSSLTFLAYNLATNPEVMKKLQKEIDATFPNKAPVQYVPLMEMEYLDCVVNESLRLYPIAARLERVAK-----ATVEVNGLVIPKDMVVMVPTWPLHRDPELWPEPEKFKPERFSKENKDTFDPYTYMPFGAGPRNCIGMRFALVMMKLAVVEILQTYDFSVCKETEFPFEL-KMGFLAPKRPIQLKLTPRS 497          

Query:  196 GLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDA-KCFTDRLDI-GSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINA---KKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKR 1557
            GL+  +   + KYG ++  Y G  P+ +++D +++K +L+K+    FT+R ++   +G +G  +  + K + W+R+R+ +SP FTSG+L+++ P +    D L  +L  +  N+PID+K      ++D++    F +  D   NPN+P  + A K   F+L+ PM+I ++F P    + + F   +E + R +++FF   + K  D+         DFL  M+++  E+ +S+ +  +   S+ LT  EI+ Q+F F+L GYETT+T+L+++ Y LA NP+A   +  EI      D  +SY+K++ L +L+  + ESLR+ PPA  +DRVC + +        QIN     +G V  +P++ +H DP  W  P  F   RF  E++   + Y++MPFG+GPRNCVGMR+A+L MKM +V LL+ + L  C +TL  I+F       P+KPI LK V R
Sbjct:   55 GLFAFNRECQAKYGDVWGLYEGRSPLLMIADPKIIKTVLVKECYSTFTNRRNVFDDDGPLGNGVAAV-KDERWKRIRSTISPCFTSGRLKQVFPFVARYADRLVNKLQKMNLNEPIDIKQFVAPYSLDVVTSASFSVETDCINNPNDPVNVQAIKATNFNLW-PMIIRMIF-PLGARLLKHF--KFEIIPRSSVDFFCDVIKKIKDQHNAGKLTRPDFLQVMIES--EIPESEVKNKKDEPSKGLTEQEILFQAFSFILGGYETTSTTLSHIFYNLAINPDAMHTLQEEIDANLQKDVPVSYDKLNGLEYLDQVLCESLRLIPPAPLLDRVCKKTM--------QINGLTIPEGTVVGIPVHLLHRDPRFWDSPDLFRPDRFSKENEGALNPYAYMPFGLGPRNCVGMRYAILVMKMVIVRLLQNYTLESCKDTLIPIQFNWKF--QPLKPIKLKFVPR 496          

Query:   34 MIEYFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            MIEYFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQGPPPLPFFGNFFDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFG LTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS
Sbjct:    1 MIEYFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQGPPPLPFFGNFFDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGALTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 509          

Query:   37 IEYFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKK---SPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            + YF D K LL  + ++L YK G  KQNLH K+GH+GPPP P+ GNF DI R G++E+DI+N  KYG IYPFY G I   IVSDE++LKQILIK+AK FTDRLDIG NGK  +KML +LKGK WERVRNLVSPTFTSGKL+KMSPL+ D ++LL+KR+   P + PID K+ FG+LTMD+IARTMFGMHID+QTNP N F+I AKKLF  S  NP++++ LFFPE+  + +K  P WEF GR T  FF +NL KA++ER+K      +YNDFL  M+KAHKEV++SDP QL  +DS+SLTN EI+AQS +FLLAG+ETTAT+LT+++YFLAKNP  Q+EVY EI+   G D+EI+YE +  +  L+AAI+E+LRICPPASR+DR CT+DVVL  SD  +I A KGDVFTVPIY+IHMD  IWP P KFD+ RFD+E+KKTR  YSFMPFGMGPRNCVGMRFA+LE+K A+V +L++FE+VPC ETLD +KFKK+    P+KPI+LK+VKRS
Sbjct:    8 LNYFLDIKPLLFVLGLYLFYKYGQTKQNLHIKVGHKGPPPWPYIGNFIDIFRFGVHEMDIMNHKKYGNIYPFYLGNIRSCIVSDEKILKQILIKEAKYFTDRLDIGFNGKSTEKMLTVLKGKDWERVRNLVSPTFTSGKLKKMSPLIADGVNLLEKRIIEYPTDTPIDFKEFFGSLTMDVIARTMFGMHIDTQTNPKNMFMIQAKKLFNVSAINPLILIFLFFPELAGLVKKIIPKWEFFGRSTFQFFNNNLYKAIEEREKLKDDGREYNDFLALMLKAHKEVDESDPNQLHNMDSKSLTNQEIMAQSLIFLLAGFETTATTLTFLSYFLAKNPNYQREVYDEIVDSIGVDDEITYETLIKMRLLDAAISETLRICPPASRIDRACTQDVVLTASDGSKITANKGDVFTVPIYSIHMDSSIWPNPNKFDIHRFDDENKKTRGAYSFMPFGMGPRNCVGMRFALLEVKWAIVTILQKFEIVPCPETLDELKFKKSGLTAPIKPILLKVVKRS 518          

Query:   37 IEYFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKK---SPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            + YF D K LL  + ++L YK G  KQNLH K+GH+GPPP P+ GNF DI R G++E+DI+N  KYG IYPFY G I   IVSDE++LKQILIK+AK FTDRLDIG NGK  +KML +LKGK WERVRNLVSPTFTSGKL+KMSPL+ D ++LL+KR+   P + PID K+ FG+LTMD+IARTMFGMHID+QTNP N F+I AKKLF  S  NP++++ LFFPE+  + +K  P WEF GR T  FF +NL KA++ER+K      +YNDFL  M+KAHKEV++SDP QL  +DS+SLTN EI+AQS +FLLAG+ETTAT+LT+++YFLAKNP  Q+EVY EI+   G D+EI+YE +  +  L+AAI+E+LRICPPASR+DR CT+DVVL  SD  +I A KGDVFTVPIY+IHMD  IWP P KFD+ RFD+E+KKTR  YSFMPFGMGPRNCVGMRFA+LE+K A+V +L++FE+VPC ETLD +KFKK+    P+KPI+LK+VKRS
Sbjct:    6 LNYFLDIKPLLFVLGLYLFYKYGQTKQNLHIKVGHKGPPPWPYIGNFIDIFRFGVHEMDIMNHKKYGNIYPFYLGNIRSCIVSDEKILKQILIKEAKYFTDRLDIGFNGKSTEKMLTVLKGKDWERVRNLVSPTFTSGKLKKMSPLIADGVNLLEKRIIEYPTDTPIDFKEFFGSLTMDVIARTMFGMHIDTQTNPKNMFMIQAKKLFNVSAINPLILIFLFFPELAGLVKKIIPKWEFFGRSTFQFFNNNLYKAIEEREKLKDDGREYNDFLALMLKAHKEVDESDPNQLHNMDSKSLTNQEIMAQSLIFLLAGFETTATTLTFLSYFLAKNPNYQREVYDEIVDSIGVDDEITYETLIKMRLLDAAISETLRICPPASRIDRACTQDVVLTASDGSKITANKGDVFTVPIYSIHMDSSIWPNPNKFDIHRFDDENKKTRGAYSFMPFGMGPRNCVGMRFALLEVKWAIVTILQKFEIVPCPETLDELKFKKSGLTAPIKPILLKVVKRS 516          

Query:   37 IEYFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKK---SPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            + YF D K LL  + ++L YK G  KQNLH K+GH+GPPP P+ GNF DI R G++E+DI+N  KYG IYPFY G I   IVSDE++LKQILIK+AK FTDRLDIG NGK  +KML +LKGK WERVRNLVSPTFTSGKL+KMSPL+ D ++LL+KR+   P + PID K+ FG+LTMD+IARTMFGMHID+QTNP N F+I AKKLF  S  NP++++ LFFPE+  + +K  P WEF GR T  FF +NL KA++ER+K      +YNDFL  M+KAHKEV++SDP QL  +DS+SLTN EI+AQS +FLLAG+ETTAT+LT+++YFLAKNP  Q+EVY EI+   G D+EI+YE +  +  L+AAI+E+LRICPPASR+DR CT+DVVL  SD  +I A KGDVFTVPIY+IHMD  IWP P KFD+ RFD+E+KKTR  YSFMPFGMGPRNCVGMRFA+LE+K A+V +L++FE+VPC ETLD +KFKK+    P+KPI+LK+VKRS
Sbjct:    5 LNYFLDIKPLLFVLGLYLFYKYGQTKQNLHIKVGHKGPPPWPYIGNFIDIFRFGVHEMDIMNHKKYGNIYPFYLGNIRSCIVSDEKILKQILIKEAKYFTDRLDIGFNGKSTEKMLTVLKGKDWERVRNLVSPTFTSGKLKKMSPLIADGVNLLEKRIIEYPTDTPIDFKEFFGSLTMDVIARTMFGMHIDTQTNPKNMFMIQAKKLFNVSAINPLILIFLFFPELAGLVKKIIPKWEFFGRSTFQFFNNNLYKAIEEREKLKDDGREYNDFLALMLKAHKEVDESDPNQLHNMDSKSLTNQEIMAQSLIFLLAGFETTATTLTFLSYFLAKNPNYQREVYDEIVDSIGVDDEITYETLIKMRLLDAAISETLRICPPASRIDRACTQDVVLTASDGSKITANKGDVFTVPIYSIHMDSSIWPNPNKFDIHRFDDENKKTRGAYSFMPFGMGPRNCVGMRFALLEVKWAIVTILQKFEIVPCPETLDELKFKKSGLTAPIKPILLKVVKRS 515          

Query:   34 MIEYFYDFKLLLCFVVIFLIYKLGTLKQNLHKKLGHQXXXXXXXXXXXXDIIRHGLYELDIINRDKYGKIYPFYFGGIPISIVSDEELLKQILIKDAKCFTDRLDIGSNGKIGQKMLIILKGKSWERVRNLVSPTFTSGKLRKMSPLMKDCIDLLDKRLAGIPENDPIDVKDVFGTLTMDMIARTMFGMHIDSQTNPNNPFIINAKKLFKFSLFNPMLILILFFPEITPIFRKFFPNWEFLGRQTMNFFVSNLNKAMDERKKSPEQYNDFLTEMMKAHKEVNDSDPEQLEILDSRSLTNSEIIAQSFLFLLAGYETTATSLTYVAYFLAKNPEAQQEVYREIIKVFGTDEEISYEKISNLPFLEAAINESLRICPPASRVDRVCTEDVVLVTSDNKQINAKKGDVFTVPIYAIHMDPEIWPEPYKFDLSRFDNESKKTRSIYSFMPFGMGPRNCVGMRFAVLEMKMALVNLLKQFELVPCAETLDVIKFKKTAFGGPVKPIILKIVKRS 1560
            ++ Y +D K LL FVV++LIYK G   QNLH KLGH GPPPLPF GN  D+ + G +  D + R KYGK+YP YFGG P+++V DEELLKQI+IK+ KCFTDR+++    K   KML +LKGK WERVRNL++PTFTSGKLRKMSPL+ D I+LL KR++  P + PID+K+ FG LTMD+IARTMFGM IDSQTNPNN F+INAK+LF FSLFN  +I+ L FP++  +FRK  P WEF G+++  FF+ N+  A+DER KS ++YNDFL  +MKAHK+  ++D E  +++DS++L+N EI+AQS +FLLAGYETTAT+L +V+YFLAKNP+AQQ++Y EI++  G++ EI+ + +  +P L+A + ESLRICPPA RVDRVCT+DV L TSD  ++  KKGD+  +PIYA+H DP IWP+P KFD  RFD + KKT   YSFMPFGMGPRNCVGMRFA+LE+K A+V++L+ FE+VPC ETL+ + FK +    P+ PI+LKIVKR 
Sbjct:    5 LLSYIFDIKFLLAFVVVYLIYKFGKQNQNLHVKLGHNGPPPLPFLGNLLDVQKMGFHTFDKMCRQKYGKLYPMYFGGSPMTVVGDEELLKQIMIKEFKCFTDRMELAFRSKRAHKMLTVLKGKDWERVRNLITPTFTSGKLRKMSPLISDGIELLKKRISNNPPDTPIDIKEFFGALTMDVIARTMFGMQIDSQTNPNNQFVINAKRLFTFSLFNSFVIIFLMFPKLGILFRKILPKWEFFGKESFQFFIDNMQMAIDERAKSTDKYNDFLA-LMKAHKKETENDSESSKLMDSKTLSNDEIMAQSLVFLLAGYETTATTLAFVSYFLAKNPDAQQDLYNEIMECLGSEREIANDTLMTMPILDAIVCESLRICPPAVRVDRVCTQDVTLETSDKTKVCFKKGDIIAIPIYAVHSDPSIWPDPEKFDYHRFDPDRKKTNGQYSFMPFGMGPRNCVGMRFALLEVKWAIVSILQNFEIVPCQETLEKLTFKISGLLSPISPILLKIVKRG 512