Inositol 1,4,5-trisphosphate receptor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014577 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]) HSP 1 Score: 2654.78 bits (6880), Expect = 0.000e+0 Identity = 1435/2785 (51.53%), Postives = 1900/2785 (68.22%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIP--MKVTQLDLDIESQ--------------------KPGSFKEXXXXXXXXXXXXXXXDAD--NTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PIVEEIPRSFD--------------QLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDII---SGKIGSDGDP------------EKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D P D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + +KEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T++ FE GV T +EEE + D+ K+ SK+++EL A K+D +L+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + ++++ E++ + G F + + + K ++ + + ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK +I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN + S ++E L++ P+ P ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + + Q E + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE F D+ SG+ S P +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVD--PDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKL--------------VLSRFE------FEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDETMDGASGENE------HKKTEEGNNKPQ-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGN--------VRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--DHYQPGEGTQATADK------------------AKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2681
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]) HSP 1 Score: 2651.31 bits (6871), Expect = 0.000e+0 Identity = 1436/2798 (51.32%), Postives = 1901/2798 (67.94%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD-------------PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIP--MKVTQLDLDIESQ--------------------KPGSFKEXXXXXXXXXXXXXXXDAD--NTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PIVEEIPRSFD--------------QLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDII---SGKIGSDGDP------------EKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D D P D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + +KEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T++ FE GV T +EEE + D+ K+ SK+++EL A K+D +L+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + ++++ E++ + G F + + + K ++ + + ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK +I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN + S ++E L++ P+ P ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + + Q E + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE F D+ SG+ S P +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKL--------------VLSRFE------FEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDETMDGASGENE------HKKTEEGNNKPQ-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGN--------VRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--DHYQPGEGTQATADK------------------AKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2696
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]) HSP 1 Score: 2634.75 bits (6828), Expect = 0.000e+0 Identity = 1435/2824 (50.81%), Postives = 1900/2824 (67.28%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIP--MKVTQLDLDIESQ--------------------KPGSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDK---------------------------------------ANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PI--------------VEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDII---SGKIGSDGDP------------EKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+ DP D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + +KEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T++ FE GV T +EEE + D+ K+ SK+++EL A K+D +L+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + ++++ E++ + G F + + + K ++ ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK +I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN + S ++E L++ P+ S ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + + Q E + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE F D+ SG+ S P +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEV--DPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKL--------------VLSRFE------FEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDETMDGASGENE------HKKTEEGNNKPQ-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGN--------VRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--DHYQPGEGTQATADK------------------AKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2720
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]) HSP 1 Score: 2633.21 bits (6824), Expect = 0.000e+0 Identity = 1438/2833 (50.76%), Postives = 1901/2833 (67.10%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD----FSAIPM------KVTQLDLDIESQKP---------------------GSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDK---------------------------------------ANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PI--------------VEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDII---SGKIGSDGDP------------EKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+ DP D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + +KEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T++ FE GV T +EEE + D+ K+ SK+++EL A K+D +L+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + P+ + + + D+E K G F + + + K ++ ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK +I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN + S ++E L++ P+ S ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + + Q E + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE F D+ SG+ S P +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEV--DPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKL--------------VLSRFE------FEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDETMDGASGENE------HKKTEEGNNKPQ-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGN--------VRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--DHYQPGEGTQATADK------------------AKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2729
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]) HSP 1 Score: 2633.21 bits (6824), Expect = 0.000e+0 Identity = 1438/2833 (50.76%), Postives = 1901/2833 (67.10%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD----FSAIPM------KVTQLDLDIESQKP---------------------GSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDK---------------------------------------ANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PI--------------VEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDII---SGKIGSDGDP------------EKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+ DP D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + +KEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T++ FE GV T +EEE + D+ K+ SK+++EL A K+D +L+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + P+ + + + D+E K G F + + + K ++ ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK +I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN + S ++E L++ P+ S ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + + Q E + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE F D+ SG+ S P +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEV--DPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKL--------------VLSRFE------FEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDETMDGASGENE------HKKTEEGNNKPQ-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGN--------VRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--DHYQPGEGTQATADK------------------AKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2729
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 1568.52 bits (4060), Expect = 0.000e+0 Identity = 1068/2879 (37.10%), Postives = 1568/2879 (54.46%), Query Frame = 3
Query: 102 LHIGDIISLYAEGNVS----GFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSL----LINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNP-----VNAGQ---PLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQ----YVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAE---IDKDPTPDLMRSKLRKSGDDDVFCLVS-----------------IPQ------------SNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDK-----EEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYN----LLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPL------SENFPI--KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANG--NSKDDESILTYYRYQLNLYSNMCLDRQYLAIN--------XXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQEN-EQKEEVKLNFG---PVMLFVEEYLNNIANNNLMFSNQEQN--KLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDI-------ESQKPGSFKEXXXXXXXXXXXXXXXDA----DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQA--EDIFSE------KDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSS-DKK---RKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHK----------------------------NYVTIKEILERLIVLC-ESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHK--NNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMM----ESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFR-LYQCTWLTADQKNNITFSMKT-----VLEIIKAKGILIPFELEHQIN------KHMLKDQAILKH-------SKAWLTIKNKKDSQFT------QYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTL-RMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQ-LSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLS-----PKQLVDVAKLAF--------------------YEDTL------------LDVDDVPSESSGETGLTGRSDLAS---------------PKEVGHNIYILAHQLSKHKRELAQLLQPG--QNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISF------YLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI----NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD-----IISGKIGS-----------------DGDPEKE-RYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRL 7967
LHIGDIISLY E + + GF+STLGLVDDRC+V+ G +PPKKFRDC FK+CP++R++AQK W K+ DS+ L+NKL AA+ E+ +NE E +K +G V+QYG+++QLLH+KSNK +TV K PA E+NAM+V LD GNEGSWF ++P YKH A+GDNV G+K++L P AG LH+SS++LLDH E+N ++ T WQ+ +FL + EN + +K GDVVRLFHA+Q+ FLT D K VFLR T R +A ATSS+ALWEV+VV +A RGG KW+ +RFKHLAT YL+AE + P + R+ L S ++ + S IP D +F++DP+ +S+ VPR S+VR+ + + WVH+T+ + +++ KV C + DKE FA++ V+ +EVRDLDFAND K L + IK + K+ + + L+ C I F+ + D +DPL + RDRQKLLREQ +L Q+F +L++P +E P+ +L+D ++ IF+ + +LCY +LK SQ YRKNQE++A++ +Q+QIG+ ++AEDT+TA+LHNN KLLEK++ + F+ L+R + +FL +L+DLC+ A QELIC + ++DI + T+I ++G EI V W + N ++LV+ A G ++ DD L YYR+QL+L S MC ++QYLAI+ +S +L L+L+C++++ P +LR SF RLM+HLHV R ++ +R+ARLW IP+ +++ Y+S E +++ G V+ VE YL + N + M Q N KLT EIVNLAK L F FY+F D L+L + LL I++ +V + +S G KE+S L + L + TKL EILQF+++VR D++IT L FK F + D S + + E + SE + + +E+ LDG GQ+ L +LL + M YP + S AL++ FRHF Q QE+L+ KQVQLLVS NDVENYRQI DL L+ L EKSELWV+ ++ S D K K+ + + D + DL + + + ++ A+ + P I C + Y I+++L RL +C DPK Q+LLKNM + V++E + +P DKK+D M +++ L+H FL+ FC N+ NQ L+K + + G L V + E T+ AI+++N +L ++VPE+++ H V IE + FL+ LQ ++ D+ I Q+ V +E+ + DEV Y D+ F L MM ES+ L+YHIELV+LLAM T GKN +E+KC S + ++ I +V C V VK YL L HCYIDT+ E+KD + + + N LL DI + ++ LE + HT+ V++ FF +P+S ++ + +V H + L + T+L +K + S + V E IK L + EH I + Q ++ S W+ I + + Q T Y + + +V+ H I + L PL AE SVLV V H PELLF + R +C GG +++LI+H + L+ + ++ LC +VLQTL +M + + LRQ LL +YFG+ + + +K E+ + E+ ++ Q IQ L+ GAS+L+ D+II S E +F + I ALL GN VQ SFY R+ + FF+A + I AQN +KS ++ +D + SL + RR +L +D N AL V + + S++ +S + N + T+S +++ + L V ++EPI R LQLLCENH LQ+ LR Q+ ++T++NLV ETL FLD +CGST G LG+ G I EHN LI Q L TLTE+CQGPCHENQN +A E NG++III+L+LN+I PL M+L LE+K ASKLLLAI+ESRHD ENA R+L N++ PKQLV K A+ ED L + + ++ ++SG + +++S P+EVGHNIYILAHQL+ H EL L + D T +AL YY + TAQIEIVR DR++ER+VFPI +IC Y+T++TK V TE D QGSKV FF E M+ EM WQ+ L+ + L W + + LW+ ++F F ++N L+ +YP P N+ ++ W + S + ++R+ + + T+L+I S + + L G L L+N I+ +++ N+G+ + ++I N +L+ IC +LGLLVHP+ Y + L D+I EETL NVI SVT+NY+S+V T +L +IL YFF+I G L+F+ DF +E + ++ IS I S D D EK+ + C+TL MC+ T YQGLRNGGGIGD+LR P+ E F +RV +D++F+ ++ VI+LNLIFGVIIDTF LR K EK++IL+N CFIC L+RS FDN++VTFE H EHN+WHYLY+IV++++KD TEFTGPESYV++ +K +NLDWFP+ +A+SL E + +Q+++K ++ +L
Sbjct: 37 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC-ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQG--KFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI--------------------------IDG-----------------EIEVGW-----APNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP--MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQS-MEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP-RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGML-----RVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEY-VDHILNNLLEDIRSLRVEKLTGAET-ATLEHYICHTVTEVLIKFFEAPYS----ALQQAKVDVHHHKKTFSEVLLELTYL---EKGKLRGSKSSRNWYRVAECIKR---LTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGKRLNRQNTLNPGHRLYGTSNSMTEHTSANVVTCYHMMIGEFKFYLHPLHAAEGSVLVEVLHTPELLFPEGSALRDQCARGGVVAKLIQHCKTLMQNKQDNLCARVLQTLCKMCDCTKQQLTHQGQQLRQLLLQRYFGHHNNHHPPLDRQQSKIGEVIEAVKEKKEETWSQERDLYAIQCKLNDAGASDLVTDIIIMEPSRE-IFLKAIHLARALLHEGNDKVQHSFYMRMKQKDIHEPFFKAILTRIQTAQNRLKSDMMSCSDSKPKVSLSATVSRRS-------STVLTPLIDAGDTGFNGALFEVPQQVRHPSIS------EMSQLSNDL----THSIPDLAPYQDEEKSTDALPPEVALVEPILRVLQLLCENHNSLLQNFLRKQS-DRTNHNLVSETLSFLDTVCGSTKGSLGVFGE-IGEHNFSLITQTLATLTEFCQGPCHENQNTMAMQE-NGLNIIISLVLNEIKPLADDHMELALEIKSQASKLLLAIMESRHDGENANRVLRNMANMSGGPKQLVHAIKQAYEMTNSNHHMLKSISRDLFRQAEDDLKKKSGPQITVNTVTLPEINVDASGIVSIHTEKNISSSLDDKFNDDDIPSVDPREVGHNIYILAHQLAIHDGELEIWLDGSDEKKDDLTREALNYYKERTAQIEIVRRDRTLERVVFPINDICSYLTKDTKDYVYNNTERDNQGSKVTEFFDEWETMYHEMIWQRKLQDRKWLSWCAFRLPLWTRLSFHFAFIVNALVARYYPLPEHSNSSISLGNLYSWFAVFSSFLLAHYLRHD-KIYLHKTSLLILASLCFLLLSSIGVTLTLYIFGILQLVNKIVHVVAFVSNKGLEDRPIAEILACRNLHYLL-VYLFIC-ILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQL 2819
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 1568.13 bits (4059), Expect = 0.000e+0 Identity = 1070/2884 (37.10%), Postives = 1568/2884 (54.37%), Query Frame = 3
Query: 102 LHIGDIISLYAEGNVS----GFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSL----LINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNP-----VNAGQ---PLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQ----YVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAE---IDKDPTPDLMRSKLRKSGDDDVFCLVS-----------------IPQ------------SNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMH----------KVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYN----LLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPL------SENFPI--KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANG--NSKDDESILTYYRYQLNLYSNMCLDRQYLAIN--------XXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQEN-EQKEEVKLNFG---PVMLFVEEYLNNIANNNLMFSNQEQN--KLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDI-------ESQKPGSFKEXXXXXXXXXXXXXXXDA----DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQA--EDIFSE------KDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSS-DKK---RKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHK----------------------------NYVTIKEILERLIVLC-ESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHK--NNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMM----ESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFR-LYQCTWLTADQKNNITFSMKT-----VLEIIKAKGILIPFELEHQIN------KHMLKDQAILKH-------SKAWLTIKNKKDSQFT------QYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTL-RMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQ-LSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLS-----PKQLVDVAKLAF--------------------YEDTL------------LDVDDVPSESSGETGLTGRSDLAS---------------PKEVGHNIYILAHQLSKHKRELAQLLQPG--QNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISF------YLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI----NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD-----IISGKIGS-----------------DGDPEKE-RYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRL 7967
LHIGDIISLY E + + GF+STLGLVDDRC+V+ G +PPKKFRDC FK+CP++R++AQK W K+ DS+ L+NKL AA+ E+ +NE E +K +G V+QYG+++QLLH+KSNK +TV K PA E+NAM+V LD GNEGSWF ++P YKH A+GDNV G+K++L P AG LH+SS++LLDH E+N ++ T WQ+ +FL + EN + +K GDVVRLFHA+Q+ FLT D K VFLR T R +A ATSS+ALWEV+VV +A RGG KW+ +RFKHLAT YL+AE + P + R+ L S ++ + S IP D +F++DP+ +S+ VPR S+VR+ + + WVH+T+ +K +H KV C + DKE FA++ V+ +EVRDLDFAND K L + IK + K+ + + L+ C I F+ + D +DPL + RDRQKLLREQ +L Q+F +L++P +E P+ +L+D ++ IF+ + +LCY +LK SQ YRKNQE++A++ +Q+QIG+ ++AEDT+TA+LHNN KLLEK++ + F+ L+R + +FL +L+DLC+ A QELIC + ++DI + T+I ++G EI V W + N ++LV+ A G ++ DD L YYR+QL+L S MC ++QYLAI+ +S +L L+L+C++++ P +LR SF RLM+HLHV R ++ +R+ARLW IP+ +++ Y+S E +++ G V+ VE YL + N + M Q N KLT EIVNLAK L F FY+F D L+L + LL I++ +V + +S G KE+S L + L + TKL EILQF+++VR D++IT L FK F + D S + + E + SE + + +E+ LDG GQ+ L +LL + M YP + S AL++ FRHF Q QE+L+ KQVQLLVS NDVENYRQI DL L+ L EKSELWV+ ++ S D K K+ + + D + DL + + + ++ A+ + P I C + Y I+++L RL +C DPK Q+LLKNM + V++E + +P DKK+D M +++ L+H FL+ FC N+ NQ L+K + + G L V + E T+ AI+++N +L ++VPE+++ H V IE + FL+ LQ ++ D+ I Q+ V +E+ + DEV Y D+ F L MM ES+ L+YHIELV+LLAM T GKN +E+KC S + ++ I +V C V VK YL L HCYIDT+ E+KD + + + N LL DI + ++ LE + HT+ V++ FF +P+S ++ + +V H + L + T+L +K + S + V E IK L + EH I + Q ++ S W+ I + + Q T Y + + +V+ H I + L PL AE SVLV V H PELLF + R +C GG +++LI+H + L+ + ++ LC +VLQTL +M + + LRQ LL +YFG+ + + +K E+ + E+ ++ Q IQ L+ GAS+L+ D+II S E +F + I ALL GN VQ SFY R+ + FF+A + I AQN +KS ++ +D + SL + RR +L +D N AL V + + S++ +S + N + T+S +++ + L V ++EPI R LQLLCENH LQ+ LR Q+ ++T++NLV ETL FLD +CGST G LG+ G I EHN LI Q L TLTE+CQGPCHENQN +A E NG++III+L+LN+I PL M+L LE+K ASKLLLAI+ESRHD ENA R+L N++ PKQLV K A+ ED L + + ++ ++SG + +++S P+EVGHNIYILAHQL+ H EL L + D T +AL YY + TAQIEIVR DR++ER+VFPI +IC Y+T++TK V TE D QGSKV FF E M+ EM WQ+ L+ + L W + + LW+ ++F F ++N L+ +YP P N+ ++ W + S + ++R+ + + T+L+I S + + L G L L+N I+ +++ N+G+ + ++I N +L+ IC +LGLLVHP+ Y + L D+I EETL NVI SVT+NY+S+V T +L +IL YFF+I G L+F+ DF +E + ++ IS I S D D EK+ + C+TL MC+ T YQGLRNGGGIGD+LR P+ E F +RV +D++F+ ++ VI+LNLIFGVIIDTF LR K EK++IL+N CFIC L+RS FDN++VTFE H EHN+WHYLY+IV++++KD TEFTGPESYV++ +K +NLDWFP+ +A+SL E + +Q+++K ++ +L
Sbjct: 27 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNA-----TEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC-ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQG--KFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI--------------------------IDG-----------------EIEVGW-----APNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP--MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQS-MEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP-RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGML-----RVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEY-VDHILNNLLEDIRSLRVEKLTGAET-ATLEHYICHTVTEVLIKFFEAPYS----ALQQAKVDVHHHKKTFSEVLLELTYL---EKGKLRGSKSSRNWYRVAECIKR---LTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGKRLNRQNTLNPGHRLYGTSNSMTEHTSANVVTCYHMMIGEFKFYLHPLHAAEGSVLVEVLHTPELLFPEGSALRDQCARGGVVAKLIQHCKTLMQNKQDNLCARVLQTLCKMCDCTKQQLTHQGQQLRQLLLQRYFGHHNNHHPPLDRQQSKIGEVIEAVKEKKEETWSQERDLYAIQCKLNDAGASDLVTDIIIMEPSRE-IFLKAIHLARALLHEGNDKVQHSFYMRMKQKDIHEPFFKAILTRIQTAQNRLKSDMMSCSDSKPKVSLSATVSRRS-------STVLTPLIDAGDTGFNGALFEVPQQVRHPSIS------EMSQLSNDL----THSIPDLAPYQDEEKSTDALPPEVALVEPILRVLQLLCENHNSLLQNFLRKQS-DRTNHNLVSETLSFLDTVCGSTKGSLGVFGE-IGEHNFSLITQTLATLTEFCQGPCHENQNTMAMQE-NGLNIIISLVLNEIKPLADDHMELALEIKSQASKLLLAIMESRHDGENANRVLRNMANMSGGPKQLVHAIKQAYEMTNSNHHMLKSISRDLFRQAEDDLKKKSGPQITVNTVTLPEINVDASGIVSIHTEKNISSSLDDKFNDDDIPSVDPREVGHNIYILAHQLAIHDGELEIWLDGSDEKKDDLTREALNYYKERTAQIEIVRRDRTLERVVFPINDICSYLTKDTKDYVYNNTERDNQGSKVTEFFDEWETMYHEMIWQRKLQDRKWLSWCAFRLPLWTRLSFHFAFIVNALVARYYPLPEHSNSSISLGNLYSWFAVFSSFLLAHYLRHD-KIYLHKTSLLILASLCFLLLSSIGVTLTLYIFGILQLVNKIVHVVAFVSNKGLEDRPIAEILACRNLHYLL-VYLFIC-ILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQL 2809
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 1566.98 bits (4056), Expect = 0.000e+0 Identity = 1070/2884 (37.10%), Postives = 1568/2884 (54.37%), Query Frame = 3
Query: 102 LHIGDIISLYAEGNVS----GFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSL----LINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNP-----VNAGQ---PLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQ----YVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAE---IDKDPTPDLMRSKLRKSGDDDVFCLVS-----------------IPQ------------SNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMH----------KVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYN----LLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPL------SENFPI--KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANG--NSKDDESILTYYRYQLNLYSNMCLDRQYLAIN--------XXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQEN-EQKEEVKLNFG---PVMLFVEEYLNNIANNNLMFSNQEQN--KLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDI-------ESQKPGSFKEXXXXXXXXXXXXXXXDA----DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQA--EDIFSE------KDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSS-DKK---RKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHK----------------------------NYVTIKEILERLIVLC-ESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHK--NNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMM----ESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFR-LYQCTWLTADQKNNITFSMKT-----VLEIIKAKGILIPFELEHQIN------KHMLKDQAILKH-------SKAWLTIKNKKDSQFT------QYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTL-RMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQ-LSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLS-----PKQLVDVAKLAF--------------------YEDTL------------LDVDDVPSESSGETGLTGRSDLAS---------------PKEVGHNIYILAHQLSKHKRELAQLLQPG--QNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISF------YLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI----NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD-----IISGKIGS-----------------DGDPEKE-RYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRL 7967
LHIGDIISLY E + + GF+STLGLVDDRC+V+ G +PPKKFRDC FK+CP++R++AQK W K+ DS+ L+NKL AA+ E+ +NE E +K +G V+QYG+++QLLH+KSNK +TV K PA E+NAM+V LD GNEGSWF ++P YKH A+GDNV G+K++L P AG LH+SS++LLDH E+N ++ T WQ+ +FL + EN + +K GDVVRLFHA+Q+ FLT D K VFLR T R +A ATSS+ALWEV+VV +A RGG KW+ +RFKHLAT YL+AE + P + R+ L S ++ + S IP D +F++DP+ +S+ VPR S+VR+ + + WVH+T+ +K +H KV C + DKE FA++ V+ +EVRDLDFAND K L + IK + K+ + + L+ C I F+ + D +DPL + RDRQKLLREQ +L Q+F +L++P +E P+ +L+D ++ IF+ + +LCY +LK SQ YRKNQE++A++ +Q+QIG+ ++AEDT+TA+LHNN KLLEK++ + F+ L+R + +FL +L+DLC+ A QELIC + ++DI + T+I ++G EI V W + N ++LV+ A G ++ DD L YYR+QL+L S MC ++QYLAI+ +S +L L+L+C++++ P +LR SF RLM+HLHV R ++ +R+ARLW IP+ +++ Y+S E +++ G V+ VE YL + N + M Q N KLT EIVNLAK L F FY+F D L+L + LL I++ +V + +S G KE+S L + L + TKL EILQF+++VR D++IT L FK F + D S + + E + SE + + +E+ LDG GQ+ L +LL + M YP + S AL++ FRHF Q QE+L+ KQVQLLVS NDVENYRQI DL L+ L EKSELWV+ ++ S D K K+ + + D + DL + + + ++ A+ + P I C + Y I+++L RL +C DPK Q+LLKNM + V++E + +P DKK+D M +++ L+H FL+ FC N+ NQ L+K + + G L V + E T+ AI+++N +L ++VPE+++ H V IE + FL+ LQ ++ D+ I Q+ V +E+ + DEV Y D+ F L MM ES+ L+YHIELV+LLAM T GKN +E+KC S + ++ I +V C V VK YL L HCYIDT+ E+KD + + + N LL DI + ++ LE + HT+ V++ FF +P+S ++ + +V H + L + T+L +K + S + V E IK L + EH I + Q ++ S W+ I + + Q T Y + + +V+ H I + L PL AE SVLV V H PELLF + R +C GG +++LI+H + L+ + ++ LC +VLQTL +M + + LRQ LL +YFG+ + + +K E+ + E+ ++ Q IQ L+ GAS+L+ D+II S E +F + I ALL GN VQ SFY R+ + FF+A + I AQN +KS ++ +D + SL + RR +L +D N AL V + + S++ +S + N + T+S +++ + L V ++EPI R LQLLCENH LQ+ LR Q+ ++T++NLV ETL FLD +CGST G LG+ G I EHN LI Q L TLTE+CQGPCHENQN +A E NG++III+L+LN+I PL M+L LE+K ASKLLLAI+ESRHD ENA R+L N++ PKQLV K A+ ED L + + ++ ++SG + +++S P+EVGHNIYILAHQL+ H EL L + D T +AL YY + TAQIEIVR DR++ER+VFPI +IC Y+T++TK V TE D QGSKV FF E M+ EM WQ+ L+ + L W + + LW+ ++F F ++N L+ +YP P N+ ++ W + S + ++R+ + + T+L+I S + + L G L L+N I+ +++ N+G+ + ++I N +L+ IC +LGLLVHP+ Y + L D+I EETL NVI SVT+NY+S+V T +L +IL YFF+I G L+F+ DF +E + ++ IS I S D D EK+ + C+TL MC+ T YQGLRNGGGIGD+LR P+ E F +RV +D++F+ ++ VI+LNLIFGVIIDTF LR K EK++IL+N CFIC L+RS FDN++VTFE H EHN+WHYLY+IV++++KD TEFTGPESYV++ +K +NLDWFP+ +A+SL E + +Q+++K ++ +L
Sbjct: 83 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNA-----TEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC-ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQG--KFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI--------------------------IDG-----------------EIEVGW-----APNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP--MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQS-MEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP-RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGML-----RVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEY-VDHILNNLLEDIRSLRVEKLTGAET-ATLEHYICHTVTEVLIKFFEAPYS----ALQQAKVDVHHHKKTFSEVLLELTYL---EKGKLRGSKSSRNWYRVAECIKR---LTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGKRLNRQNTLNPGHRLYGTSNSMTEHTSANVVTCYHMMIGEFKFYLHPLHAAEGSVLVEVLHTPELLFPEGSALRDQCARGGVVAKLIQHCKTLMQNKQDNLCARVLQTLCKMCDCTKQQLTHQGQQLRQLLLQRYFGHHNNHHPPLDRQQSKIGEVIEAVKEKKEETWSQERDLYAIQCKLNDAGASDLVTDIIIMEPSRE-IFLKAIHLARALLHEGNDKVQHSFYMRMKQKDIHEPFFKAILTRIQTAQNRLKSDMMSCSDSKPKVSLSATVSRRS-------STVLTPLIDAGDTGFNGALFEVPQQVRHPSIS------EMSQLSNDL----THSIPDLAPYQDEEKSTDALPPEVALVEPILRVLQLLCENHNSLLQNFLRKQS-DRTNHNLVSETLSFLDTVCGSTKGSLGVFGE-IGEHNFSLITQTLATLTEFCQGPCHENQNTMAMQE-NGLNIIISLVLNEIKPLADDHMELALEIKSQASKLLLAIMESRHDGENANRVLRNMANMSGGPKQLVHAIKQAYEMTNSNHHMLKSISRDLFRQAEDDLKKKSGPQITVNTVTLPEINVDASGIVSIHTEKNISSSLDDKFNDDDIPSVDPREVGHNIYILAHQLAIHDGELEIWLDGSDEKKDDLTREALNYYKERTAQIEIVRRDRTLERVVFPINDICSYLTKDTKDYVYNNTERDNQGSKVTEFFDEWETMYHEMIWQRKLQDRKWLSWCAFRLPLWTRLSFHFAFIVNALVARYYPLPEHSNSSISLGNLYSWFAVFSSFLLAHYLRHD-KIYLHKTSLLILASLCFLLLSSIGVTLTLYIFGILQLVNKIVHVVAFVSNKGLEDRPIAEILACRNLHYLL-VYLFIC-ILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQL 2865
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 1559.66 bits (4037), Expect = 0.000e+0 Identity = 1071/2905 (36.87%), Postives = 1569/2905 (54.01%), Query Frame = 3
Query: 102 LHIGDIISLYAEGNVS----GFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSL----LINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNP-----VNAGQ---PLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQ----YVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAE---IDKDPTPDLMRSKLRKSGDDDVFCLVS-----------------IPQ------------SNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMH----------KVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYN----LLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPL------SENFPI--KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANG--NSKDDESILTYYRYQLNLYSNMCLDRQYLAIN--------XXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQEN-EQKEEVKLNFG---PVMLFVEEYLNNIANNNLMFSNQEQN--KLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDI-------ESQKPGSFKEXXXXXXXXXXXXXXXDA----DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQA--EDIFSE------KDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSS-DKKR---KDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHK----------------------------NYVTIKEILERLIVLC-ESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHK--NNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMM----ESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFR-LYQCTWLTADQKNNITFSMKT-----VLEIIKAKGILIPFELEHQIN------KHMLKDQAILKH-------SKAWLTIKNKKDSQFT-----------QYERPSLQNGLE----------------TRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTL-RMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQ-LSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLS-----PKQLVDVAKLAF--------------------YEDTL------------LDVDDVPSESSGETGLTGRSDLAS---------------PKEVGHNIYILAHQLSKHKRELAQLLQPG--QNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISF------YLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI----NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD-----IISGKIGS-----------------DGDPEKE-RYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRL 7967
LHIGDIISLY E + + GF+STLGLVDDRC+V+ G +PPKKFRDC FK+CP++R++AQK W K+ DS+ L+NKL AA+ E+ +NE E +K +G V+QYG+++QLLH+KSNK +TV K PA E+NAM+V LD GNEGSWF ++P YKH A+GDNV G+K++L P AG LH+SS++LLDH E+N ++ T WQ+ +FL + EN + +K GDVVRLFHA+Q+ FLT D K VFLR T R +A ATSS+ALWEV+VV +A RGG KW+ +RFKHLAT YL+AE + P + R+ L S ++ + S IP D +F++DP+ +S+ VPR S+VR+ + + WVH+T+ +K +H KV C + DKE FA++ V+ +EVRDLDFAND K L + IK + K+ + + L+ C I F+ + D +DPL + RDRQKLLREQ +L Q+F +L++P +E P+ +L+D ++ IF+ + +LCY +LK SQ YRKNQE++A++ +Q+QIG+ ++AEDT+TA+LHNN KLLEK++ + F+ L+R + +FL +L+DLC+ A QELIC + ++DI + T+I ++G EI V W + N ++LV+ A G ++ DD L YYR+QL+L S MC ++QYLAI+ +S +L L+L+C++++ P +LR SF RLM+HLHV R ++ +R+ARLW IP+ +++ Y+S E +++ G V+ VE YL + N + M Q N KLT EIVNLAK L F FY+F D L+L + LL I++ +V + +S G KE+S L + L + TKL EILQF+++VR D++IT L FK F + D S + + E + SE + + +E+ LDG GQ+ L +LL + M YP + S AL++ FRHF Q QE+L+ KQVQLLVS NDVENYRQI DL L+ L EKSELWV+ ++ S D K K+ + + D + DL + + + ++ A+ + P I C + Y I+++L RL +C DPK Q+LLKNM + V++E + +P DKK+D M +++ L+H FL+ FC N+ NQ L+K + + G L V + E T+ AI+++N +L ++VPE+++ H V IE + FL+ LQ ++ D+ I Q+ V +E+ + DEV Y D+ F L MM ES+ L+YHIELV+LLAM T GKN +E+KC S + ++ I +V C V VK YL L HCYIDT+ E+KD + + + N LL DI + ++ LE + HT+ V++ FF +P+ + ++ + +V H + L + T+L +K + S + V E IK L + EH I + Q ++ S W+ I + Q R + QN L + +V+ H I + L PL AE SVLV V H PELLF + R +C GG +++LI+H + L+ + ++ LC +VLQTL +M + + LRQ LL +YFG+ + + +K E+ + E+ ++ Q IQ L+ GAS+L+ D+II S E +F + I ALL GN VQ SFY R+ + FF+A + I AQN +KS ++ +D + SL + RR +L +D N AL V + + S++ +S + N + T+S +++ + L V ++EPI R LQLLCENH LQ+ LR Q+ ++T++NLV ETL FLD +CGST G LG+ G I EHN LI Q L TLTE+CQGPCHENQN +A E NG++III+L+LN+I PL M+L LE+K ASKLLLAI+ESRHD ENA R+L N++ PKQLV K A+ ED L + + ++ ++SG + +++S P+EVGHNIYILAHQL+ H EL L + D T +AL YY + TAQIEIVR DR++ER+VFPI +IC Y+T++TK V TE D QGSKV FF E M+ EM WQ+ L+ + L W + + LW+ ++F F ++N L+ +YP P N+ ++ W + S + ++R+ + + T+L+I S + + L G L L+N I+ +++ N+G+ + ++I N +L+ IC +LGLLVHP+ Y + L D+I EETL NVI SVT+NY+S+V T +L +IL YFF+I G L+F+ DF +E + ++ IS I S D D EK+ + C+TL MC+ T YQGLRNGGGIGD+LR P+ E F +RV +D++F+ ++ VI+LNLIFGVIIDTF LR K EK++IL+N CFIC L+RS FDN++VTFE H EHN+WHYLY+IV++++KD TEFTGPESYV++ +K +NLDWFP+ +A+SL E + +Q+++K ++ +L
Sbjct: 37 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNA-----TEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC-ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQG--KFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI--------------------------IDG-----------------EIEVGW-----APNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP--MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQS-MEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP-RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLR-----VETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEY-VDHILNNLLEDIRSLRVEKLTGAET-ATLEHYICHTVTEVLIKFFEAPY----SALQQAKVDVHHHKKTFSEVLLELTYL---EKGKLRGSKSSRNWYRVAECIKR---LTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGKMSQDSQSDYDSDSSQGPCQISRLNRQNTLNPGHRLYGTSNSMTEHTSANVVTCYHMMIGEFKFYLHPLHAAEGSVLVEVLHTPELLFPEGSALRDQCARGGVVAKLIQHCKTLMQNKQDNLCARVLQTLCKMCDCTKQQLTHQGQQLRQLLLQRYFGHHNNHHPPLDRQQSKIGEVIEAVKEKKEETWSQERDLYAIQCKLNDAGASDLVTDIIIMEPSRE-IFLKAIHLARALLHEGNDKVQHSFYMRMKQKDIHEPFFKAILTRIQTAQNRLKSDMMSCSDSKPKVSLSATVSRRS-------STVLTPLIDAGDTGFNGALFEVPQQVRHPSIS------EMSQLSNDL----THSIPDLAPYQDEEKSTDALPPEVALVEPILRVLQLLCENHNSLLQNFLRKQS-DRTNHNLVSETLSFLDTVCGSTKGSLGVFGE-IGEHNFSLITQTLATLTEFCQGPCHENQNTMAMQE-NGLNIIISLVLNEIKPLADDHMELALEIKSQASKLLLAIMESRHDGENANRVLRNMANMSGGPKQLVHAIKQAYEMTNSNHHMLKSISRDLFRQAEDDLKKKSGPQITVNTVTLPEINVDASGIVSIHTEKNISSSLDDKFNDDDIPSVDPREVGHNIYILAHQLAIHDGELEIWLDGSDEKKDDLTREALNYYKERTAQIEIVRRDRTLERVVFPINDICSYLTKDTKDYVYNNTERDNQGSKVTEFFDEWETMYHEMIWQRKLQDRKWLSWCAFRLPLWTRLSFHFAFIVNALVARYYPLPEHSNSSISLGNLYSWFAVFSSFLLAHYLRHD-KIYLHKTSLLILASLCFLLLSSIGVTLTLYIFGILQLVNKIVHVVAFVSNKGLEDRPIAEILACRNLHYLL-VYLFIC-ILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQL 2840
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1]) HSP 1 Score: 1548.87 bits (4009), Expect = 0.000e+0 Identity = 1069/2904 (36.81%), Postives = 1566/2904 (53.93%), Query Frame = 3
Query: 102 LHIGDIISLYAEGNVS----GFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSL----LINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNP-----VNAGQ---PLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQ----YVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK-------DPTPDLMRSKLRKS----------------GDDDVF------CLVSIPQ------------SNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMH----------KVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYN----LLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPL------SENFPI--KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANG--NSKDDESILTYYRYQLNLYSNMCLDRQYLAIN--------XXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQEN-EQKEEVKLNFG---PVMLFVEEYLNNIANNNLMFSNQEQN--KLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDI-------ESQKPGSFKEXXXXXXXXXXXXXXXDA----DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQA--EDIFSE------KDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSS-DKKR---KDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHK----------------------------NYVTIKEILERLIVLC-ESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHK--NNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMM----ESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFR-LYQCTWLTADQKNNITFSMKT-----VLEIIKAKGILIPFELEHQIN------KHMLKDQAILKH-------SKAWLTIKNKKDSQFTQ------YERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIE------------FDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQ-LSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLS-----PKQLVDVAKLAF--------------------YEDTL------------LDVDDVPSESSGETGLTGRSDLAS---------------PKEVGHNIYILAHQLSKHKRELAQLLQPG--QNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISF------YLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI----NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD-----IISGKIGS-----------------DGDPEKE-RYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRL 7967
LHIGDIISLY E + + GF+STLGLVDDRC+V+ G +PPKKFRDC FK+CP++R++AQK W K+ DS+ L+NKL AA+ E+ +NE E +K +G V+QYG+++QLLH+KSNK +TV K PA E+NAM+V LD GNEGSWF ++P YKH A+GDNV G+K++L P AG LH+SS++LLDH E+N ++ T WQ+ +FL + EN + +K GDVVRLFHA+Q+ FLT D K VFLR T R +A ATSS+ALWEV+VV +A RGG KW+ +RFKHLAT YL+AE + + P L+ + +KS G + V +IP D +F++DP+ +S+ VPR S+VR+ + + WVH+T+ +K +H KV C + DKE FA++ V+ +EVRDLDFAND K L + IK + K+ + + L+ C I F+ + D +DPL + RDRQKLLREQ +L Q+F +L++P +E P+ +L+D ++ IF+ + +LCY +LK SQ YRKNQE++A++ +Q+QIG+ ++AEDT+TA+LHNN KLLEK++ + F+ L+R + +FL +L+DLC+ A QELIC + ++DI + T+I ++G EI V W + N ++LV+ A G ++ DD L YYR+QL+L S MC ++QYLAI+ +S +L L+L+C++++ P +LR SF RLM+HLHV R ++ +R+ARLW IP+ +++ Y+S E +++ G V+ VE YL + N + M Q N KLT EIVNLAK L F FY+F D L+L + LL I++ +V + +S G KE+S L + L + TKL EILQF+++VR D++IT L FK F + D S + + E + SE + + +E+ LDG GQ+ L +LL + M YP + S AL++ FRHF Q QE+L+ KQVQLLVS NDVENYRQI DL L+ L EKSELWV+ ++ S D K K+ + + D + DL + + + ++ A+ + P I C + Y I+++L RL +C DPK Q+LLKNM + V++E + +P DKK+D M +++ L+H FL+ FC N+ NQ L+K + + G L V + E T+ AI+++N +L ++VPE+++ H V IE + FL+ LQ ++ D+ I Q+ V +E+ + DEV Y D+ F L MM ES+ L+YHIELV+LLAM T GKN +E+KC S + ++ I +V C V VK YL L HCYIDT+ E+KD + + + N LL DI + ++ LE + HT+ V++ FF +P+S ++ + +V H + L + T+L +K + S + V E IK L + EH I + Q ++ S W+ I + + Q T Y + + +V+ H I + L PL AE SVLV V H PELLF + R +C GG +++LI+H + L+ + ++ LC +VLQTL M + +K LRQ LL +YFG+ + + +K E+ + E+ ++ Q IQ L+ GAS+L+ D+II S E +F + I ALL GN VQ SFY R+ + FF+A + I AQN +KS ++ +D + S + P +D N AL V + + S++ +S + N + T+S +++ + L V ++EPI R LQLLCENH LQ+ LR Q+ ++T++NLV ETL FLD +CGST G LG+ G I EHN LI Q L TLTE+CQGPCHENQN +A E NG++III+L+LN+I PL M+L LE+K ASKLLLAI+ESRHD ENA R+L N++ PKQLV K A+ ED L + + ++ ++SG + +++S P+EVGHNIYILAHQL+ H EL L + D T +AL YY + TAQIEIVR DR++ER+VFPI +IC Y+T++TK V TE D QGSKV FF E M+ EM WQ+ L+ + L W + + LW+ ++F F ++N L+ +YP P N+ ++ W + S + ++R+ + + T+L+I S + + L G L L+N I+ +++ N+G+ + ++I N +L+ IC +LGLLVHP+ Y + L D+I EETL NVI SVT+NY+S+V T +L +IL YFF+I G L+F+ DF +E + ++ IS I S D D EK+ + C+TL MC+ T YQGLRNGGGIGD+LR P+ E F +RV +D++F+ ++ VI+LNLIFGVIIDTF LR K EK++IL+N CFIC L+RS FDN++VTFE H EHN+WHYLY+IV++++KD TEFTGPESYV++ +K +NLDWFP+ +A+SL E + +Q+++K ++ +L
Sbjct: 37 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRPPLLSALSQKSRPMLERTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNA-----TEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC-ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQG--KFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI--------------------------IDG-----------------EIEVGW-----APNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP--MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQS-MEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP-RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLR-----VETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEY-VDHILNNLLEDIRSLRVEKLTGAET-ATLEHYICHTVTEVLIKFFEAPYS----ALQQAKVDVHHHKKTFSEVLLELTYL---EKGKLRGSKSSRNWYRVAECIKR---LTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGKRLNRQNTLNPGHRLYGTSNSMTEHTSANVVTCYHMMIGEFKFYLHPLHAAEGSVLVEVLHTPELLFPEGSALRDQCARGGVVAKLIQHCKTLMQNKQDNLCARVLQTLCKMCDCTKQQLTHQGHRVYNSSVEKGQQLRQLLLQRYFGHHNNHHPPLDRQQSKIGEVIEAVKEKKEETWSQERDLYAIQCKLNDAGASDLVTDIIIMEPSRE-IFLKAIHLARALLHEGNDKVQHSFYMRMKQKDIHEPFFKAILTRIQTAQNRLKSDMMSCSDSKPKVSSTVLTPL----------------IDAGDTGFNGALFEVPQQVRHPSIS------EMSQLSNDL----THSIPDLAPYQDEEKSTDALPPEVALVEPILRVLQLLCENHNSLLQNFLRKQS-DRTNHNLVSETLSFLDTVCGSTKGSLGVFGE-IGEHNFSLITQTLATLTEFCQGPCHENQNTMAMQE-NGLNIIISLVLNEIKPLADDHMELALEIKSQASKLLLAIMESRHDGENANRVLRNMANMSGGPKQLVHAIKQAYEMTNSNHHMLKSISRDLFRQAEDDLKKKSGPQITVNTVTLPEINVDASGIVSIHTEKNISSSLDDKFNDDDIPSVDPREVGHNIYILAHQLAIHDGELEIWLDGSDEKKDDLTREALNYYKERTAQIEIVRRDRTLERVVFPINDICSYLTKDTKDYVYNNTERDNQGSKVTEFFDEWETMYHEMIWQRKLQDRKWLSWCAFRLPLWTRLSFHFAFIVNALVARYYPLPEHSNSSISLGNLYSWFAVFSSFLLAHYLRHD-KIYLHKTSLLILASLCFLLLSSIGVTLTLYIFGILQLVNKIVHVVAFVSNKGLEDRPIAEILACRNLHYLL-VYLFIC-ILGLLVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIFGVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSLQDSELDTDQSEVKQMKDQL 2830
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0078687) HSP 1 Score: 2426.36 bits (6287), Expect = 0.000e+0 Identity = 1399/2899 (48.26%), Postives = 1882/2899 (64.92%), Query Frame = 3
Query: 78 NNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYG-TVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQP-LHVSS-YDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSG----------DDDVFC-----------------LVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVED--SGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP-----IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKG-KDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEI------------YKRXXXXXXXXXXXXXXGFEDD-------------DLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQ-KEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD---------FSAIPMKVTQLDLDIESQKP-----------------GSFKEXXXXXXXXXXXXXXXD---ADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------------NEID--------------------------ISKICQQAEDIFS-EKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLC-ESDDP----KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMES---QRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLF-NTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNV---------LKINSSTKKEEL--SNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMII-----LAADGNSQNSLENVMPRRRVRD---RSN---IPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVF------FKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQN------DSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSV---IWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEF--LIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD-----------IISGKIGSD-----------------------GDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
N I S SFLH+GDI+SLYAEG+V GF+STLGLVDDR VV P AGDL PPKKFRDC KICPM+R+SAQKQFW A KQ A TD L+ +LH AAE+EK QNE E+KKL+GT +QYG V+QLLH+KSNK LTVNKRLP+LLEKNAMRV LD+NGNEGSWF ++PFYK ++GD VVVGDKV L+PVNA Q LHV++ Y+L D+ GCKE+N ++ +TSW+I+LF+E+KEN + +LKGGDVVRLFHAEQEKFLT DEYKK +VFLRTTGRT+AT+ATSSKALWE+EVV D+CRGGAG W+SL+RFKHLATG YLAAE + D + M S SG D + C LVS+P S D+ S+F +D T R D VP+SS+VR+++ C+ WVH+TSIPID ++DKP+M V C+ +KEDKEAFA++ VS EVRDLDFAND KVL+ VT K+ + ++IN+++ + +LL +++F+ +E+ + + L+ +K RDRQKLLREQ ILKQ+FKIL+ P ++ +++D+L+D K+ ++NI RLCYRIL+LSQQDYRKNQEYIAK +MQKQIGY ILAEDTITALLHNNRKLLEKHIT +EI TF+ L+RK + RFL +LSDLC+SN AI +TQELICK + + N+DIL++T++ YK E D G ++D D ++N + T T ++ EI + W S+++ +L + G + +IL YYR+QLNL+SNMCL+RQYLA+N LS L I LILKC+++++ P LRASFCRLM+HLHVDRDPQE VTPV+YARLW++IP KM I +YD +Q+ +Q K+ + F + FVE YL N+A +F++QEQNKLT E+V LA+ LIYFGFY+F D LRL KTLL ILD F++ + + + + E++ GS ++ + I+ K+ + L+M+TKL+ IEILQFIL+VRLD++I+CLL IFK F+ NE D + I QAE IF E+ + +DLDG+GG+ FLRVLL+LIMH Y +VSGAL +LFRHF+QRQEVLQ F+QVQLLVS +DVE+Y+QIK+DLD LR VEKSELWVYK AK + + A+ G + A+ L+ + Q Y +KEIL R+ C + P K RKHEQRLL+N+G HTV+++LLQ P+D+K+D M+E++ LAH FLQ FC GN+ NQ +LH + DLFL PG L EA+T+ AI+KDN+ LCN V +KVVQH+V CIE HG V +L+FLQT+++A++Q+IR+CQDMV+ ELI+ G++VLVFYND F H + MM+ + +L + PL+YH+ELVKLLA T GKNVY+EIKC++LLS++DI I+CHP C VKEAY+ FL HCYIDTEVE+K+I++ + MW LF + L+DI + +K L+ V + + ++ +FF SPFS+Q+ +++++Q + LLQ R+ QC WL+ + N+ ++T+ E K + I +P ELE Q+ K + + + WL K ++ + SL RS+I+ L D + LE QL+P+++AE+S+LV + +R ELLF TEAR +CESGGFI +LIKHTE LL EE++C+KVL+TLR M+++D+ + +K + LRQ LL++YF K + + + K+ L P + + R+ L ++Q++LD +GAS+L+++L+I + +F E +E GIALLEGGN +QK +++ D + FF+ F + +AQ EIKS + +AA + N+ + R +SN I L+++L +A L R N +++ ++S IS NS + ++ K+ ++ +LSN V++++PI RFLQLLCENH ++Q+LLR+Q NKT+ NLV ETL FLDCICGST+GGLGLLGLYINEHNV LINQ L LTEYCQGPCHENQN IA HESNG+DII ALILN+INPLG RMDLVLELK+NASKLLLAI+ESR DSENAERIL N++PKQLV+VA A++++ L+D D E + G SP+EVGHNIYIL HQL++H +ELA LL+ ++ D+ T QAL YYA HTAQIEIVR+DR++E+IVFPIPEICEY+T +TK K+ E D+QGSKV FF + MF EM+WQK LR++ LLFW+S++M LWS+I F +V+N+++ +YPF +N P + + W+ + SLV + + + F+ ++I++ F L L +G + + + I+S+ GN+G +K I ++F L H + GL+ HP FYS+ L D++ REETL+NVIRSVT+N RS+VLT +L +IL Y F+I G++FF+DDF + +F + +S + D G KER CD+L MC+ TTL QGLRNGGGIGDILR PS KE F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+ IL+ TCFIC+LNRSAFDNKTV+FEEH + EHNMWHYLYFIVL+KVKDPTEFTGPESYV M+KA L+WFP+ RAMSLAA + + EQ +L+S+Q++L T +I NLS QL ELK+ MTEQRKQKQR LL
Sbjct: 4 NIIGSASFLHLGDIVSLYAEGSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQKQFWKAAKQSASSNTDPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYKKQYHVFLRTTGRTSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAM-SATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPVSPVEVRDLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKALEFTIKNPIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILRLSQQDYRKNQEYIAKHFGLMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMHNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILIETQVKALRTGSGPVRCYKGNSEDVCLATLAEDAGDDEDRSDVQSTSTTTTWDSASLNEDDGTP------STGDKYEIHLKWTGQPTSRSMADLASCDGGEL--EAAILNYYRHQLNLFSNMCLNRQYLALNELSPRLDIDLILKCMSDETMPYELRASFCRLMLHLHVDRDPQEPVTPVKYARLWSEIPSKMSIQDYDGKNQQPDQNKQACRAKFNTTIAFVENYLCNVATKVWLFTDQEQNKLTFEVVKLARDLIYFGFYSFSDLLRLTKTLLSILDCVSDTSSGEFASTDIDSVEEETNAEAEGGVLRSIGDINTVMTSLALGSVGQAIAAPTISLQQRKSVSQLMKEYPLVMDTKLKIIEILQFILDVRLDYRISCLLSIFKREFDESEVAASAASNEASQQQSQQQEPQTPGSSNETDPLDSAESVAAGAAAAAATTARQKNIDLESIGVQAEGIFDCERSDAANLDLDGQGGRTFLRVLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKSDLDILRQSVEKSELWVYK------------------------AKATDELGATDAGGD-AVSLEYNAALSQEQRNEYRKVKEILIRMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKELMCLAHEFLQNFCLGNQQNQVLLHNHLDLFLNPGIL-----------EAKTVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVAYLQFLQTVVRAENQFIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPLKYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYIDTEVEMKEIYA-SGHMWSLFEKSFLVDI--NQLITNPAAASNKTLQAYVLNGVTNLLGSFFASPFSDQSAIVQSRQLIFVQLLQAAHRITQCRWLSLGDRFNVENCIRTLTESAKMRSIALPPELEQQVATMSSKTAMLTRQTTKWLLA--SKQPKYEAQQAASLMRW--DRSIIEGLQDIVSLLEDQLKPVVEAELSLLVDILYRSELLFPAGTEARKRCESGGFIRKLIKHTEKLLEEKEERMCVKVLRTLREMMAIDVNYGEKGDALRQTLLLRYFQTKSTPRLPEDEVPLLAAPLMDPAKQNHLVTHGPGAKYLQRAGKTLH--EMQNHLDREGASDLVVELVIKSVHSPNIFVEAVELGIALLEGGNPIIQKGMFQKFLSDDLNQAFFKVFFEKMKDAQQEIKSTVTVNTTDIAAKAHEHKQDTNLELDKIARKHGLKSNGVVITEELKRELHNA------GLATARAYGNARNIHSGEESSAIS----------VNSPLEDILAEKLEKHKDSRDQRNQLSNKVLVMQPILRFLQLLCENHNPDMQNLLRNQN-NKTNNNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVALINQTLEALTEYCQGPCHENQNCIATHESNGLDIITALILNNINPLGENRMDLVLELKNNASKLLLAIMESRGDSENAERILYNMNPKQLVEVACKAYHQEELIDEQDDGDEP--DAGSDDDDATVSPREVGHNIYILCHQLAQHNKELAGLLKASEDPQSASFDAKTSQALMYYATHTAQIEIVRNDRTLEQIVFPIPEICEYLTTDTKIKILNTAERDDQGSKVADFFDKAEEMFNEMKWQKKLRSQPLLFWISSYMSLWSNILFNCVVVINMIVAFFYPF---DNTVPELSSHISLLFWIITIFSLVIVLALPRESGIRTFIGSVILRFIFLLGPESTLCLLGVVTVTLKSVHIVSIMGNKGTLEKQLIKIITDFQLLYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSIIGYMFFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGNCQAAKEVAPPSAGGGEVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRAPSSKEGLFVARVIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNLSTQLHELKDHMTEQRKQKQRLGLL 2826
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0078686) HSP 1 Score: 2425.97 bits (6286), Expect = 0.000e+0 Identity = 1400/2890 (48.44%), Postives = 1878/2890 (64.98%), Query Frame = 3
Query: 78 NNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYG-TVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQP-LHVSS-YDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSG----------DDDVFC-----------------LVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVED--SGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP-----IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKG-KDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEI------------YKRXXXXXXXXXXXXXXGFEDD-------------DLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQ-KEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKP-----------------GSFKEXXXXXXXXXXXXXXXD---ADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------------NEID--------------------------ISKICQQAEDIFS-EKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLC-ESDDP----KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMES---QRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLF-NTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNV---------LKINSSTKKEEL--SNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMII-----LAADGNSQNSLENVMPRRRVRD---RSN---IPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVF------FKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQN------DSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSV---IWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEF--LIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD-----------IISGKIGSD-----------------------GDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
N I S SFLH+GDI+SLYAEG+V GF+STLGLVDDR VV P AGDL PPKKFRDC KICPM+R+SAQKQFW A KQ A TD L+ +LH AAE+EK QNE E+KKL+GT +QYG V+QLLH+KSNK LTVNKRLP+LLEKNAMRV LD+NGNEGSWF ++PFYK ++GD VVVGDKV L+PVNA Q LHV++ Y+L D+ GCKE+N ++ +TSW+I+LF+E+KEN + +LKGGDVVRLFHAEQEKFLT DEYKK +VFLRTTGRT+AT+ATSSKALWE+EVV D+CRGGAG W+SL+RFKHLATG YLAAE + D + M S SG D + C LVS+P S D+ S+F +D T R D VP+SS+VR+++ C+ WVH+TSIPID ++DKP+M V C+ +KEDKEAFA++ VS EVRDLDFAND KVL+ VT K+ + ++IN+++ + +LL +++F+ +E+ + + L+ +K RDRQKLLREQ ILKQ+FKIL+ P ++ +++D+L+D K+ ++NI RLCYRIL+LSQQDYRKNQEYIAK +MQKQIGY ILAEDTITALLHNNRKLLEKHIT +EI TF+ L+RK + RFL +LSDLC+SN AI +TQELICK + + N+DIL++T++ YK E D G ++D D ++N + T T ++ EI + W S+++ +L + G + +IL YYR+QLNL+SNMCL+RQYLA+N LS L I LILKC+++++ P LRASFCRLM+HLHVDRDPQE VTPV+YARLW++IP KM I +YD +Q+ +Q K+ + F + FVE YL N+A +F++QEQNKLT E+V LA+ LIYFGFY+F D LRL KTLL ILD + DI+S+ GS ++ + I+ K+ + L+M+TKL+ IEILQFIL+VRLD++I+CLL IFK F+ NE D + I QAE IF E+ + +DLDG+GG+ FLRVLL+LIMH Y +VSGAL +LFRHF+QRQEVLQ F+QVQLLVS +DVE+Y+QIK+DLD LR VEKSELWVYK AK + + A+ G + A+ L+ + Q Y +KEIL R+ C + P K RKHEQRLL+N+G HTV+++LLQ P+D+K+D M+E++ LAH FLQ FC GN+ NQ +LH + DLFL PG L EA+T+ AI+KDN+ LCN V +KVVQH+V CIE HG V +L+FLQT+++A++Q+IR+CQDMV+ ELI+ G++VLVFYND F H + MM+ + +L + PL+YH+ELVKLLA T GKNVY+EIKC++LLS++DI I+CHP C VKEAY+ FL HCYIDTEVE+K+I++ + MW LF + L+DI + +K L+ V + + ++ +FF SPFS+Q+ +++++Q + LLQ R+ QC WL+ + N+ ++T+ E K + I +P ELE Q+ K + + + WL K ++ + SL RS+I+ L D + LE QL+P+++AE+S+LV + +R ELLF TEAR +CESGGFI +LIKHTE LL EE++C+KVL+TLR M+++D+ + +K + LRQ LL++YF K + + + K+ L P + + R+ L ++Q++LD +GAS+L+++L+I + +F E +E GIALLEGGN +QK +++ D + FF+ F + +AQ EIKS + +AA + N+ + R +SN I L+++L +A L R N +++ ++S IS NS + ++ K+ ++ +LSN V++++PI RFLQLLCENH ++Q+LLR+Q NKT+ NLV ETL FLDCICGST+GGLGLLGLYINEHNV LINQ L LTEYCQGPCHENQN IA HESNG+DII ALILN+INPLG RMDLVLELK+NASKLLLAI+ESR DSENAERIL N++PKQLV+VA A++++ L+D D E + G SP+EVGHNIYIL HQL++H +ELA LL+ ++ D+ T QAL YYA HTAQIEIVR+DR++E+IVFPIPEICEY+T +TK K+ E D+QGSKV FF + MF EM+WQK LR++ LLFW+S++M LWS+I F +V+N+++ +YPF +N P + + W+ + SLV + + + F+ ++I++ F L L +G + + + I+S+ GN+G +K I ++F L H + GL+ HP FYS+ L D++ REETL+NVIRSVT+N RS+VLT +L +IL Y F+I G++FF+DDF + +F + +S + D G KER CD+L MC+ TTL QGLRNGGGIGDILR PS KE F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+ IL+ TCFIC+LNRSAFDNKTV+FEEH + EHNMWHYLYFIVL+KVKDPTEFTGPESYV M+KA L+WFP+ RAMSLAA + + EQ +L+S+Q++L T +I NLS QL ELK+ MTEQRKQKQR LL
Sbjct: 4 NIIGSASFLHLGDIVSLYAEGSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQKQFWKAAKQSASSNTDPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYKKQYHVFLRTTGRTSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAM-SATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPVSPVEVRDLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKALEFTIKNPIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILRLSQQDYRKNQEYIAKHFGLMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMHNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILIETQVKALRTGSGPVRCYKGNSEDVCLATLAEDAGDDEDRSDVQSTSTTTTWDSASLNEDDGTP------STGDKYEIHLKWTGQPTSRSMADLASCDGGEL--EAAILNYYRHQLNLFSNMCLNRQYLALNELSPRLDIDLILKCMSDETMPYELRASFCRLMLHLHVDRDPQEPVTPVKYARLWSEIPSKMSIQDYDGKNQQPDQNKQACRAKFNTTIAFVENYLCNVATKVWLFTDQEQNKLTFEVVKLARDLIYFGFYSFSDLLRLTKTLLSILDCVSDTSSGEFASTDIDSEGGVLRSIGDINTVMTSLALGSVGQAIAAPTISLQQRKSVSQLMKEYPLVMDTKLKIIEILQFILDVRLDYRISCLLSIFKREFDESEVAASAASNEASQQQSQQQEPQTPGSSNETDPLDSAESVAAGAAAAAATTARQKNIDLESIGVQAEGIFDCERSDAANLDLDGQGGRTFLRVLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKSDLDILRQSVEKSELWVYK------------------------AKATDELGATDAGGD-AVSLEYNAALSQEQRNEYRKVKEILIRMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKELMCLAHEFLQNFCLGNQQNQVLLHNHLDLFLNPGIL-----------EAKTVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVAYLQFLQTVVRAENQFIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPLKYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYIDTEVEMKEIYA-SGHMWSLFEKSFLVDI--NQLITNPAAASNKTLQAYVLNGVTNLLGSFFASPFSDQSAIVQSRQLIFVQLLQAAHRITQCRWLSLGDRFNVENCIRTLTESAKMRSIALPPELEQQVATMSSKTAMLTRQTTKWLLA--SKQPKYEAQQAASLMRW--DRSIIEGLQDIVSLLEDQLKPVVEAELSLLVDILYRSELLFPAGTEARKRCESGGFIRKLIKHTEKLLEEKEERMCVKVLRTLREMMAIDVNYGEKGDALRQTLLLRYFQTKSTPRLPEDEVPLLAAPLMDPAKQNHLVTHGPGAKYLQRAGKTLH--EMQNHLDREGASDLVVELVIKSVHSPNIFVEAVELGIALLEGGNPIIQKGMFQKFLSDDLNQAFFKVFFEKMKDAQQEIKSTVTVNTTDIAAKAHEHKQDTNLELDKIARKHGLKSNGVVITEELKRELHNA------GLATARAYGNARNIHSGEESSAIS----------VNSPLEDILAEKLEKHKDSRDQRNQLSNKVLVMQPILRFLQLLCENHNPDMQNLLRNQN-NKTNNNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVALINQTLEALTEYCQGPCHENQNCIATHESNGLDIITALILNNINPLGENRMDLVLELKNNASKLLLAIMESRGDSENAERILYNMNPKQLVEVACKAYHQEELIDEQDDGDEP--DAGSDDDDATVSPREVGHNIYILCHQLAQHNKELAGLLKASEDPQSASFDAKTSQALMYYATHTAQIEIVRNDRTLEQIVFPIPEICEYLTTDTKIKILNTAERDDQGSKVADFFDKAEEMFNEMKWQKKLRSQPLLFWISSYMSLWSNILFNCVVVINMIVAFFYPF---DNTVPELSSHISLLFWIITIFSLVIVLALPRESGIRTFIGSVILRFIFLLGPESTLCLLGVVTVTLKSVHIVSIMGNKGTLEKQLIKIITDFQLLYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSIIGYMFFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGNCQAAKEVAPPSAGGGEVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRAPSSKEGLFVARVIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNLSTQLHELKDHMTEQRKQKQRLGLL 2817
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Fly
Match: Itp-r83A (gene:FBgn0010051 transcript:FBtr0344265) HSP 1 Score: 2425.97 bits (6286), Expect = 0.000e+0 Identity = 1400/2890 (48.44%), Postives = 1878/2890 (64.98%), Query Frame = 3
Query: 78 NNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYG-TVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQP-LHVSS-YDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSG----------DDDVFC-----------------LVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVED--SGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP-----IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKG-KDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEI------------YKRXXXXXXXXXXXXXXGFEDD-------------DLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQ-KEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKP-----------------GSFKEXXXXXXXXXXXXXXXD---ADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------------NEID--------------------------ISKICQQAEDIFS-EKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLC-ESDDP----KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMES---QRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLF-NTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNV---------LKINSSTKKEEL--SNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMII-----LAADGNSQNSLENVMPRRRVRD---RSN---IPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVF------FKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQN------DSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSV---IWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEF--LIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD-----------IISGKIGSD-----------------------GDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
N I S SFLH+GDI+SLYAEG+V GF+STLGLVDDR VV P AGDL PPKKFRDC KICPM+R+SAQKQFW A KQ A TD L+ +LH AAE+EK QNE E+KKL+GT +QYG V+QLLH+KSNK LTVNKRLP+LLEKNAMRV LD+NGNEGSWF ++PFYK ++GD VVVGDKV L+PVNA Q LHV++ Y+L D+ GCKE+N ++ +TSW+I+LF+E+KEN + +LKGGDVVRLFHAEQEKFLT DEYKK +VFLRTTGRT+AT+ATSSKALWE+EVV D+CRGGAG W+SL+RFKHLATG YLAAE + D + M S SG D + C LVS+P S D+ S+F +D T R D VP+SS+VR+++ C+ WVH+TSIPID ++DKP+M V C+ +KEDKEAFA++ VS EVRDLDFAND KVL+ VT K+ + ++IN+++ + +LL +++F+ +E+ + + L+ +K RDRQKLLREQ ILKQ+FKIL+ P ++ +++D+L+D K+ ++NI RLCYRIL+LSQQDYRKNQEYIAK +MQKQIGY ILAEDTITALLHNNRKLLEKHIT +EI TF+ L+RK + RFL +LSDLC+SN AI +TQELICK + + N+DIL++T++ YK E D G ++D D ++N + T T ++ EI + W S+++ +L + G + +IL YYR+QLNL+SNMCL+RQYLA+N LS L I LILKC+++++ P LRASFCRLM+HLHVDRDPQE VTPV+YARLW++IP KM I +YD +Q+ +Q K+ + F + FVE YL N+A +F++QEQNKLT E+V LA+ LIYFGFY+F D LRL KTLL ILD + DI+S+ GS ++ + I+ K+ + L+M+TKL+ IEILQFIL+VRLD++I+CLL IFK F+ NE D + I QAE IF E+ + +DLDG+GG+ FLRVLL+LIMH Y +VSGAL +LFRHF+QRQEVLQ F+QVQLLVS +DVE+Y+QIK+DLD LR VEKSELWVYK AK + + A+ G + A+ L+ + Q Y +KEIL R+ C + P K RKHEQRLL+N+G HTV+++LLQ P+D+K+D M+E++ LAH FLQ FC GN+ NQ +LH + DLFL PG L EA+T+ AI+KDN+ LCN V +KVVQH+V CIE HG V +L+FLQT+++A++Q+IR+CQDMV+ ELI+ G++VLVFYND F H + MM+ + +L + PL+YH+ELVKLLA T GKNVY+EIKC++LLS++DI I+CHP C VKEAY+ FL HCYIDTEVE+K+I++ + MW LF + L+DI + +K L+ V + + ++ +FF SPFS+Q+ +++++Q + LLQ R+ QC WL+ + N+ ++T+ E K + I +P ELE Q+ K + + + WL K ++ + SL RS+I+ L D + LE QL+P+++AE+S+LV + +R ELLF TEAR +CESGGFI +LIKHTE LL EE++C+KVL+TLR M+++D+ + +K + LRQ LL++YF K + + + K+ L P + + R+ L ++Q++LD +GAS+L+++L+I + +F E +E GIALLEGGN +QK +++ D + FF+ F + +AQ EIKS + +AA + N+ + R +SN I L+++L +A L R N +++ ++S IS NS + ++ K+ ++ +LSN V++++PI RFLQLLCENH ++Q+LLR+Q NKT+ NLV ETL FLDCICGST+GGLGLLGLYINEHNV LINQ L LTEYCQGPCHENQN IA HESNG+DII ALILN+INPLG RMDLVLELK+NASKLLLAI+ESR DSENAERIL N++PKQLV+VA A++++ L+D D E + G SP+EVGHNIYIL HQL++H +ELA LL+ ++ D+ T QAL YYA HTAQIEIVR+DR++E+IVFPIPEICEY+T +TK K+ E D+QGSKV FF + MF EM+WQK LR++ LLFW+S++M LWS+I F +V+N+++ +YPF +N P + + W+ + SLV + + + F+ ++I++ F L L +G + + + I+S+ GN+G +K I ++F L H + GL+ HP FYS+ L D++ REETL+NVIRSVT+N RS+VLT +L +IL Y F+I G++FF+DDF + +F + +S + D G KER CD+L MC+ TTL QGLRNGGGIGDILR PS KE F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+ IL+ TCFIC+LNRSAFDNKTV+FEEH + EHNMWHYLYFIVL+KVKDPTEFTGPESYV M+KA L+WFP+ RAMSLAA + + EQ +L+S+Q++L T +I NLS QL ELK+ MTEQRKQKQR LL
Sbjct: 4 NIIGSASFLHLGDIVSLYAEGSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQKQFWKAAKQSASSNTDPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYKKQYHVFLRTTGRTSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAM-SATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFVLDATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPVSPVEVRDLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKALEFTIKNPIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILRLSQQDYRKNQEYIAKHFGLMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMHNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILIETQVKALRTGSGPVRCYKGNSEDVCLATLAEDAGDDEDRSDVQSTSTTTTWDSASLNEDDGTP------STGDKYEIHLKWTGQPTSRSMADLASCDGGEL--EAAILNYYRHQLNLFSNMCLNRQYLALNELSPRLDIDLILKCMSDETMPYELRASFCRLMLHLHVDRDPQEPVTPVKYARLWSEIPSKMSIQDYDGKNQQPDQNKQACRAKFNTTIAFVENYLCNVATKVWLFTDQEQNKLTFEVVKLARDLIYFGFYSFSDLLRLTKTLLSILDCVSDTSSGEFASTDIDSEGGVLRSIGDINTVMTSLALGSVGQAIAAPTISLQQRKSVSQLMKEYPLVMDTKLKIIEILQFILDVRLDYRISCLLSIFKREFDESEVAASAASNEASQQQSQQQEPQTPGSSNETDPLDSAESVAAGAAAAAATTARQKNIDLESIGVQAEGIFDCERSDAANLDLDGQGGRTFLRVLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKSDLDILRQSVEKSELWVYK------------------------AKATDELGATDAGGD-AVSLEYNAALSQEQRNEYRKVKEILIRMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKELMCLAHEFLQNFCLGNQQNQVLLHNHLDLFLNPGIL-----------EAKTVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVAYLQFLQTVVRAENQFIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPLKYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYIDTEVEMKEIYA-SGHMWSLFEKSFLVDI--NQLITNPAAASNKTLQAYVLNGVTNLLGSFFASPFSDQSAIVQSRQLIFVQLLQAAHRITQCRWLSLGDRFNVENCIRTLTESAKMRSIALPPELEQQVATMSSKTAMLTRQTTKWLLA--SKQPKYEAQQAASLMRW--DRSIIEGLQDIVSLLEDQLKPVVEAELSLLVDILYRSELLFPAGTEARKRCESGGFIRKLIKHTEKLLEEKEERMCVKVLRTLREMMAIDVNYGEKGDALRQTLLLRYFQTKSTPRLPEDEVPLLAAPLMDPAKQNHLVTHGPGAKYLQRAGKTLH--EMQNHLDREGASDLVVELVIKSVHSPNIFVEAVELGIALLEGGNPIIQKGMFQKFLSDDLNQAFFKVFFEKMKDAQQEIKSTVTVNTTDIAAKAHEHKQDTNLELDKIARKHGLKSNGVVITEELKRELHNA------GLATARAYGNARNIHSGEESSAIS----------VNSPLEDILAEKLEKHKDSRDQRNQLSNKVLVMQPILRFLQLLCENHNPDMQNLLRNQN-NKTNNNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVALINQTLEALTEYCQGPCHENQNCIATHESNGLDIITALILNNINPLGENRMDLVLELKNNASKLLLAIMESRGDSENAERILYNMNPKQLVEVACKAYHQEELIDEQDDGDEP--DAGSDDDDATVSPREVGHNIYILCHQLAQHNKELAGLLKASEDPQSASFDAKTSQALMYYATHTAQIEIVRNDRTLEQIVFPIPEICEYLTTDTKIKILNTAERDDQGSKVADFFDKAEEMFNEMKWQKKLRSQPLLFWISSYMSLWSNILFNCVVVINMIVAFFYPF---DNTVPELSSHISLLFWIITIFSLVIVLALPRESGIRTFIGSVILRFIFLLGPESTLCLLGVVTVTLKSVHIVSIMGNKGTLEKQLIKIITDFQLLYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSIIGYMFFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGNCQAAKEVAPPSAGGGEVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRAPSSKEGLFVARVIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNLSTQLHELKDHMTEQRKQKQRLGLL 2817
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088639) HSP 1 Score: 109.383 bits (272), Expect = 5.206e-23 Identity = 77/231 (33.33%), Postives = 132/231 (57.14%), Query Frame = 3
Query: 7197 LFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFP 7889
F++ LLD+ +TL +++SVT N + LVLT +L I+ Y +T+ FF+ F ++ E D E ++ C + C LY+G+R GGGIGD + P + + +R++ D++F+F V +I+L +I G+IID F LR + + + + CFIC + + FD F+ H ++EHN+ +Y++F++ + K TE+TG E+YV M + ++ D+FP
Sbjct: 4878 FFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRK-FYIQEE-------------DEEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPD-GDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFP 5093 HSP 2 Score: 59.3066 bits (142), Expect = 8.250e-8 Identity = 131/572 (22.90%), Postives = 222/572 (38.81%), Query Frame = 3
Query: 420 YGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNG-NEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDV--LKGGDVVRLFHAEQEKFLTCDEYKKD--QYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFC-TGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHL---------TINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKE----IDRDRQKLLREQNILKQIFKILES---PLSENFP---IKMDDLTDQKHVIFRNICRLCYRILK-----LSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLL----EKHITVSEINTFINLIRK-GKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENN---QDILV 2021
YG I L H S+ L + +K + V L + E W+ V P K + G+ V VGD + L V + LH + + V NA T W + + M V + GGDV+R FH E + ++ Q + + +++LW +E+ + GG W R +H+ TG+YL D ++ K S FCL + +D + E D + + + C T W+ S K+ + K A+L E+ + + S + + A + K S+ TQ I L +I +KV N + + L + D ++ E K+ R+RQ L +E+ +L I + ++ S+ F + D+ +I + +L I+K +Q ++ +L G G+L D + +L ++ + L ++HI V I+L+ K G+D + L L LC+ N VA+ +Q IC L N Q +LV
Sbjct: 99 YGNAILLRHHNSDMYLAC-LSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKENEQSIV-----NASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWGREAGQNIVI----YEGGVVMAQARSLWRLELA-RTKWTGGFINWYHPMRIRHITTGRYLGV---NDSNELILVKKEEASIATTTFCLRQ--EKDDEKKVLE-DKDLEVIGSPIIKYGDTTVIVQHCETSLWLSYKSYETKKKGVGKVEEKQ--AILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFITALETLQSNRRHSIFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEEGVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQFANSNRLNWLFSRLGSQASSEGSGML--DVLHCVLIDSPEALNMMRDEHIKV-----IISLLEKHGRDP--KVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLV 642 HSP 3 Score: 52.7582 bits (125), Expect = 6.943e-6 Identity = 36/99 (36.36%), Postives = 49/99 (49.49%), Query Frame = 3
Query: 5844 IFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFL--------DCICGSTSXXXXXXXXYINEHN-VGLINQNLRTLTEYCQGPCHENQNAIAQ 6113
+FRF+QL CE H E Q+ LR QA N T+ N+V T+ +L D +S + N + + +Q TLTE QGPC NQ A+A
Sbjct: 4000 LFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKAIEVASQVFNTLTEVIQGPCTLNQQALAH 4098
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088640) HSP 1 Score: 109.383 bits (272), Expect = 5.296e-23 Identity = 77/231 (33.33%), Postives = 132/231 (57.14%), Query Frame = 3
Query: 7197 LFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFP 7889
F++ LLD+ +TL +++SVT N + LVLT +L I+ Y +T+ FF+ F ++ E D E ++ C + C LY+G+R GGGIGD + P + + +R++ D++F+F V +I+L +I G+IID F LR + + + + CFIC + + FD F+ H ++EHN+ +Y++F++ + K TE+TG E+YV M + ++ D+FP
Sbjct: 4892 FFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRK-FYIQEE-------------DEEVDKKCHDMLTCFVFHLYKGVRAGGGIGDEIGDPD-GDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFP 5107 HSP 2 Score: 59.3066 bits (142), Expect = 8.182e-8 Identity = 131/572 (22.90%), Postives = 222/572 (38.81%), Query Frame = 3
Query: 420 YGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNG-NEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDV--LKGGDVVRLFHAEQEKFLTCDEYKKD--QYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFC-TGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHL---------TINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKE----IDRDRQKLLREQNILKQIFKILES---PLSENFP---IKMDDLTDQKHVIFRNICRLCYRILK-----LSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLL----EKHITVSEINTFINLIRK-GKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENN---QDILV 2021
YG I L H S+ L + +K + V L + E W+ V P K + G+ V VGD + L V + LH + + V NA T W + + M V + GGDV+R FH E + ++ Q + + +++LW +E+ + GG W R +H+ TG+YL D ++ K S FCL + +D + E D + + + C T W+ S K+ + K A+L E+ + + S + + A + K S+ TQ I L +I +KV N + + L + D ++ E K+ R+RQ L +E+ +L I + ++ S+ F + D+ +I + +L I+K +Q ++ +L G G+L D + +L ++ + L ++HI V I+L+ K G+D + L L LC+ N VA+ +Q IC L N Q +LV
Sbjct: 99 YGNAILLRHHNSDMYLAC-LSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKENEQSIV-----NASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWGREAGQNIVI----YEGGVVMAQARSLWRLELA-RTKWTGGFINWYHPMRIRHITTGRYLGV---NDSNELILVKKEEASIATTTFCLRQ--EKDDEKKVLE-DKDLEVIGSPIIKYGDTTVIVQHCETSLWLSYKSYETKKKGVGKVEEKQ--AILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFITALETLQSNRRHSIFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEEGVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQFANSNRLNWLFSRLGSQASSEGSGML--DVLHCVLIDSPEALNMMRDEHIKV-----IISLLEKHGRDP--KVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLV 642 HSP 3 Score: 52.7582 bits (125), Expect = 6.715e-6 Identity = 36/99 (36.36%), Postives = 49/99 (49.49%), Query Frame = 3
Query: 5844 IFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFL--------DCICGSTSXXXXXXXXYINEHN-VGLINQNLRTLTEYCQGPCHENQNAIAQ 6113
+FRF+QL CE H E Q+ LR QA N T+ N+V T+ +L D +S + N + + +Q TLTE QGPC NQ A+A
Sbjct: 4014 LFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKEIIDPAGKANFFKAIEVASQVFNTLTEVIQGPCTLNQQALAH 4112
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2]) HSP 1 Score: 2633.98 bits (6826), Expect = 0.000e+0 Identity = 1409/2757 (51.11%), Postives = 1890/2757 (68.55%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGK---QSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPM--KVTQLDLDIESQ--------------------KPGSF---KEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFEN----------EIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPS-LQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN--------PIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGD-------------------------PEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL-RPENWPATNQQ*A 8108
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP +GDL+NPPKKFRDC F++CPM+R+SAQKQFW A K G TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LDS GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N + +LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWE+EVV D CRGGAG W+SLFRFKHLATG YLAAE+D + + +R++LR + ++ LVS+P ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDKEE+KP+M ++G + +KEDKEAFAIV V EVRDLDFAND SKVL+ + K++ TI N+++ V LL ++FF+ + ++G D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELIC + + N DIL++T++ +L+ VE + P + +EEE+ + W N +SK+++EL A KDD+ +++YYRYQLNL++ MCLDRQYLAI +S +L + LIL+C++++ P +LRASFCRLM+H+HVDRDPQE V PV+YARLW++IP K+ ID+YD+ + ++E+K F M FVE YL ++ N+ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + + +++ ES+ + G F ++ + + ++ L+M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGAL +LFRHF+QRQEVL FKQVQLLV++ DV+NY+QIK+DLD LR VEKSELWVYK + D ED G + K D NY +KEIL RL LC + P KS+K +QRLL+NMGAH+V++ELLQIP++K D++MQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L+ MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI +V ++ D LE VT T+M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C+WL QK ++ +K + ++ K++ I IP +L+ Q+N +K +++ TI N + S R S L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFIS+LIKHT+ LL NEE+LCIKVLQTLR M++ D + +K+ LRQ L+ +Y+GN +++ L+N S +LS ++Q +LD +GAS+L+IDLI++ +S +R+F+E I IALLEGGN +Q+SF+ RL D S+KFF+ F + AQ EIK+ + + +D S +++D + I +R+QL +A+ + +A R+ + + E+ N+ E ++ +S + I++PI R +QLLCENH RELQ+ LR Q NK +YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ + +LTEYCQGPCHENQN IA HE NGIDIIIALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + + +V GE G + ASP+ VGHNIYILAHQL++H +EL +L+PG D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K +V TE DEQGSK+ FF + +F EM WQK LRA+ +L+W S +M WS I+F ++MN+L+ +YP P+ + +++W +++SL + + + + + I+++ F + + P L +G N+ N +IF++S GNRG + + ++ EFL H +I LG+ VH FYS+ L DLI REETLLNVI+SVT+N RS+VLT +L +IL Y F+I G++ F+DDF + +D IS K + +KER CD+L MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTVTFEEH + EHNMWHYL+FIVL+KVKD TEFTGPESYV+EMI+ NLDWFP+ RAMSL + + E EQN+++SLQ +LE T ++ISNLS QLTELK QMTEQRKQKQR LL P++ QQ A
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPESGDLNNPPKKFRDCQFRLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKEAILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAELDSE--HEALRARLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPIDKEEEKPVMLRIGTSAVKEDKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKLLEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICNAVLNPANADILIETKL-----------------------VLSRFEVESGEGP--MESEIDEEEVWLFWKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDVDLILRCMSDEDLPYDLRASFCRLMLHMHVDRDPQEQVMPVKYARLWSEIPSKIAIDDYDN---DGTSRDEIKERFALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVSTIYPINKMEKGDESKSSNVMKSIHGVGELMTQVVLRGGGFLPTTPTTPPDGDVVKTQTEPEKEDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDENGPNSIPNIPALDFENIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSNVEKSELWVYKRQGDEGMDGGDGLPAEDS------------------GSDKK-------KTDGNGSDNYRDVKEILLRLSKLCVQEGPSGKKSKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVRMQEIMKLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAITMQHIFMNNFQLCSEMNERVVQHFVHCIETHGRHVQYLKFLQTIVKAENKFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHKDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRVCNNTSDRKHADTTLESYVTETVMSIVTTFFSSPFSDQSTSLQTRQPVFVQLLQGVFRVYHCSWLLPSQKGSVESCIKVLSDVAKSRAIAIPVDLDSQVNNLFVKSNNVVQK-----TILNWRLSARNASRRDSTLTASKDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFISKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKSEALRQVLVNRYYGN--------FKPGGRRDSLTNFRGGGGGGGGGGGSAGSRGELSLAEVQCHLDREGASDLVIDLIMNATS-DRIFQESILLAIALLEGGNPVIQRSFFCRLTGDNKSEKFFKVFYERMKLAQQEIKATVTVNTSDLGS-----------KLKDVAVITEEVREQLLEASTVTKKAFSTYRREADAD--------------------EHLNATEGPSSTAEKNQDENEMSVIITIMQPILRLMQLLCENHNRELQNFLRCQN-NKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTVESLTEYCQGPCHENQNCIATHECNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEI----EVEHTDDGENGEEEHA--ASPRNVGHNIYILAHQLARHNKELQAMLKPGGTYGEGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPNICEFLTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPILYWCSRNMSFWSSISFNLAVLMNLLVAFFYPLEGGGTLEPH-LSALLWAAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTLFLLGAFNVGNKVIFLMSFVGNRGTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFYSLLLFDLIYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIIFKDDFILT---VDRISNKTLGENSRCMGEFLAGAVCRKEENFQSSALVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQMTEQRKQKQRIGLLGHPQHMNVNPQQPA 2638
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3]) HSP 1 Score: 2613.18 bits (6772), Expect = 0.000e+0 Identity = 1414/2773 (50.99%), Postives = 1891/2773 (68.19%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQG--AQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD-------------PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW----DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKP---------------------GSF---KEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHF-------------------ENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDD---PKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN-------PI--VEEIPRSFD--QLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQ---NSLENVMPRRRVRDRSNIPAM--LRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPA-KENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------------PEFLDIISGKIGSDGDPEKE--RYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGD+ SLYAEG+ SGF+STLGLVDDRCVVQP AGDL+NPPKKFRDC F++CPM+R+SAQKQFW A K G + TD++L+NKLH AA+LEK QN+ E+KKL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD+ GNEGSWF +QPFYK ++GDNVV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+C TSW+I LF+++ +N + VLKGGDVVRLFHAEQEKFLTCDE++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE++ D +++R++ R D ++ LVS+P ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDKEE+KP+M ++G + LKEDKEAFAIV VS EVRDLDFAND SKVL+ + K++ TI N+++ V LL +++F+ + S D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELIC + N DIL++T+ L ++ E EEEE+ W D+G + SK+++EL A +D+ ++ YYRYQLNL++ MCLDRQYLAIN +S++L + LIL+C++++ P +LRASFCR+M+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YD+ + +EVK F M FVE YL ++ + FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD I + LD E K G F + + + L+M+TKL+ IEILQFILNVRLD++I+CLLCIFK F + +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VS AL +LFRHF+QRQEVLQ FKQVQLLV++ DVENY+QIK+DLD LR +VEKSELWVYK + S D + +V + H +K + +S PK++ T NY +KEIL RL LC + K++K +QRLL+NMGAH+V++ELLQIP++K D++MQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L+ MM +R +L + L+YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF+ L+D+ +V ++ D LE VT TIM ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK N+ +K + ++ K + I IP +L+ Q+N +K I+ K + +W L+++N ++DS T + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF HTEA KCESGGFI +LIKHT+ LL NEE+LCIKVLQTLR M++ D + +K LRQ L+ +Y+G S ++E L++ P+ ++ P ++S +++Q +LD +GAS+L+IDLI++ +S +RVF E I IALLEGGNT +Q SF++RL DK+S+KFF+ F + AQ EIK+ + + GN + N+ + P+RR S + R+QL +A+ + +A + R+ + +E + + + E +S ++I++PI RFLQLLCENH R+LQ+ LR Q NK +YNLVCETLQFLDCICGST+GGLGLLGLYIN+HNV LINQ + +LTEYCQGPCH+NQN IA HESNGIDIIIALILNDINPLGR RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K+A+ + +E E G ASP+ VGHNIYILAHQLS+H +EL LL+PG D QALEYY KHT+QIEIVR DR+ME+IVFP+P IC ++T E+K +V TE DEQGSK+ FF + +F EM+WQK LRA+ +L+W S +M WS+++F +++N+L+ +YP E+ + ++W+ ++ SL + +V + V + ++++ F + + L +G N+ N I+F++S GNRG + + + + EFL H ++ +LGL H FYS+ L DL+ REETLLNVI+SVT+N RS+VLT +LG+IL Y F+I G++FF+DDF +E F D +G SD E + R CD+L MC+ T L GLR+GGG+GD+LRKPS +E+ F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ K+EIL+ TCFIC L R FDNKTVTFEEH + EHN+WHYL+FIVL++VKD TE+TGPESYV++MIK NLDWFP+ RAMSL + + E EQN+L+SLQ +LE T +++SNL++QLTELK QMTEQRK KQR LL
Sbjct: 7 SFLHIGDVCSLYAEGSTSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGDVVRLFHAEQEKFLTCDEHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLRIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHICRLCYRVLRYSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETK-------------------------LVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAKDGHTEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQLDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDN---DGTSSDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHISTPF-HIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEVKAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKTEFDESNSQSEPSLSPESPASVQGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVYKRQGS------DSGLDAGEVTPEAH--HKGVINSSRSN---------KPKVESTSSSNYRVVKEILLRLSKLCVLEGISGKKNKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVQMQEIMTLAHQFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRSVHYLKFLQTIVKAENKFIKKCQDIVMAELVTAGEDVLVFYNDRASFQSLVQMMRLERERLDESSALRYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYVDTEVEMKEIYTSNH-MWKLFDDFLVDVCRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPFSDQSTSLQTRQPVFVQLLQGVFRVYHCNWLLPGQKGNVEACIKVLSDVAKGRAIAIPVDLDCQVNNLFMKSNNIVQKTALSWRLSVRNATRRDSVLT--------TSRDYRNIIERLQDIVSALEERLRPLVQAELSVLVDVLHRPELLFPEHTEAHRKCESGGFICKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKGEALRQLLVNRYYG---------FRSGGRRESLTSFGNSTLTPVGPIKSQPGGLSRAEMSLMEVQCHLDREGASDLVIDLIMNTTS-DRVFHESILLAIALLEGGNTIIQHSFFKRLTEDKNSEKFFRVFYDRMKVAQVEIKATVTVNTSDLGNKRRDDNTPDKDTPQRRRGKDSGVVVTDDAREQLLEASAATKKAFGSYRRDAD--------------------PEETFGTADGDKGGGDKGTEQGEMSPVILIMQPILRFLQLLCENHNRDLQNFLRCQN-NKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINQHNVALINQTVESLTEYCQGPCHDNQNCIATHESNGIDIIIALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVMKMAYQQGE--------AEFEDEEQENGEDHAASPRNVGHNIYILAHQLSRHNKELQILLKPGGED----QALEYYTKHTSQIEIVRQDRTMEQIVFPVPNICSFLTNESKLRVYYGTERDEQGSKINDFFLHADDLFNEMRWQKKLRAQPVLYWCSRNMSFWSNVSFNLAVLINLLVAFFYPLDGVSESQLEPSLSLLLWVCLLGSLGFVLMSPRPNAVRVLVISTVLQLGFSVGLQHMLTLLGAFNVCNKIVFMLSFVGNRGSFTRGYRVMVMDREFLFHLLYLLICILGLFGHVFFYSLLLFDLVNREETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYMFFKDDFILEVNRISNGTLEEGVTLPAGFCDARNGSCLSDDVDEDDVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMTEQRKHKQRLGLL 2668
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3]) HSP 1 Score: 2600.47 bits (6739), Expect = 0.000e+0 Identity = 1411/2794 (50.50%), Postives = 1887/2794 (67.54%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQG--AQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD-------------PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW----DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKP---------------------GSF---KEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHF-------------------ENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDD---PKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKY--------------FGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQ---NSLENVMPRRRVRDRSNIPAM--LRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPA-KENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWS--DINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGD------------------------------------PEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGD+ SLYAEG+ SGF+STLGLVDDRCVVQP AGDL+NPPKKFRDC F++CPM+R+SAQKQFW A K G + TD++L+NKLH AA+LEK QN+ E+KKL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD+ GNEGSWF +QPFYK ++GDNVV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+C TSW+I LF+++ +N + VLKGGDVVRLFHAEQEKFLTCDE++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE++ D +++R++ R D ++ LVS+P ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDKEE+KP+M ++G + LKEDKEAFAIV VS EVRDLDFAND SKVL+ + K++ TI N+++ V LL +++F+ + S D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELIC + N DIL++T+ L ++ E EEEE+ W D+G + SK+++EL A +D+ ++ YYRYQLNL++ MCLDRQYLAIN +S++L + LIL+C++++ P +LRASFCR+M+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YD+ + ++EVK F M FVE YL ++ + FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD I + LD E K G F + + + L+M+TKL+ IEILQFILNVRLD++I+CLLCIFK F + +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VS AL +LFRHF+QRQEVLQ FKQVQLLV++ DVENY+QIK+DLD LR +VEKSELWVYK + S D + +V + H K + PK++ T NY +KEIL RL LC + K++K +QRLL+NMGAH+V++ELLQIP++K D++MQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L+ MM +R +L + L+YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF+ L+D+ +V ++ D LE VT TIM ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK N+ +K + ++ K++ I IP +L+ Q+N +K I+ K + +W L+++N ++DS T + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF HTEA KCESGGFI +LIKHT+ LL NEE+LCIKVLQTLR M++ D + +K LRQ L+ +Y FGN V I S K +++ + + R+ ++S +++Q +LD +GAS+L+IDLI++ +S +RVF E I IALLEGGNT +Q SF++RL DK+S+KFF+ F + AQ EIK+ + + GN + N+ + P+RR S + R+QL +A+ + +A + R+ + +E + + + E +S ++I++PI RFLQLLCENH R+LQ+ LR Q NK +YNLVCETLQFLDCICGST+GGLGLLGLYIN+HNV LINQ + +LTEYCQGPCH+NQN IA HESNGIDIIIALILNDINPLGR RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K+A+ + +E E G ASP+ VGHNIYILAHQLS+H +EL LL+PG DQALEYY KHT+QIEIVR DR+ME+IVFP+P IC ++T E+K +V TE DEQGSK+ FF + +F EM+WQK LRA+ +L+W S +M WS+++F +++N+L+ +YP E+ + ++W+ ++ SL + +V + V + ++++ F + + L +G N+ N I+F++S GNRG + + ++ EFL H ++ +LGL H FYS+ L DL+ REETLLNVI+SVT+N RS+VLT +LG+IL Y F+I G++FF+DDF +E + + D + ER CD+L MC+ T L GLR+GGG+GD+LRKPS +E+ F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ K+EIL+ TCFIC L R FDNKTVTFEEH + EHN+WHYL+FIVL++VKD TE+TGPESYV++MIK NLDWFP+ RAMSL + + E EQN+L+SLQ +LE T +++SNL++QLTELK QMTEQRK KQR LL
Sbjct: 7 SFLHIGDVCSLYAEGSTSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGDVVRLFHAEQEKFLTCDEHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLRIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHICRLCYRVLRYSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETK-------------------------LVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAKDGHTEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQLDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDN---DGTSRDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHISTPF-HIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEVKAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKTEFDESNSQSEPSLSPESPASVQGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVYKRQGS------DSGLDAGEVTPEAHHKVRIRSNK--------------PKVESTSSSNYRVVKEILLRLSKLCVLEGISGKKNKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVQMQEIMTLAHQFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRSVHYLKFLQTIVKAENKFIKKCQDIVMAELVTAGEDVLVFYNDRASFQSLVQMMRLERERLDESSALRYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYVDTEVEMKEIYTSNH-MWKLFDDFLVDVCRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPFSDQSTSLQTRQPVFVQLLQGVFRVYHCNWLLPGQKGNVEACIKVLSDVGKSRAIAIPVDLDCQVNNLFMKSNNIVQKTALSWRLSVRNATRRDSVLT--------TSRDYRNIIERLQDIVSALEERLRPLVQAELSVLVDVLHRPELLFPEHTEAHRKCESGGFICKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKGEALRQLLVNRYYGFRSGGRRESLTSFGNSTLTPVGPIKSQPGKYIVTSGSIWGLSRA--EMSLMEVQCHLDREGASDLVIDLIMNTTS-DRVFHESILLAIALLEGGNTIIQHSFFKRLTEDKNSEKFFRVFYDRMKVAQVEIKATVTVNTSDLGNKRRDDNTPDKDTPQRRRGKDSGVVVTDDAREQLLEASAATKKAFGSYRRDAD--------------------PEETFGTADGDKGGGDKGTEQGEMSPVILIMQPILRFLQLLCENHNRDLQNFLRCQN-NKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINQHNVALINQTVESLTEYCQGPCHDNQNCIATHESNGIDIIIALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVMKMAYQQGE--------AEFEDEEQENGEDHAASPRNVGHNIYILAHQLSRHNKELQILLKPGGE----DQALEYYTKHTSQIEIVRQDRTMEQIVFPVPNICSFLTNESKLRVYYGTERDEQGSKINDFFLHADDLFNEMRWQKKLRAQPVLYWCSRNMSFWSNVSFNLAVLINLLVAFFYPLDGVSESQLEPSLSLLLWVCLLGSLGFVLMSPRPNAVRVLVISTVLQLGFSVGLQHMLTLLGAFNVCNKIVFMLSFVGNRGSFTRGYRVMVMDREFLFHLLYLLICILGLFGHVFFYSLLLFDLVNREETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYMFFKDDFILEVNRISNGTLAKAQTSDLLAVRRLFTIIINSCILILKCHKIHCLNPTDCVCFIDDVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMTEQRKHKQRLGLL 2693
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3]) HSP 1 Score: 2600.08 bits (6738), Expect = 0.000e+0 Identity = 1411/2794 (50.50%), Postives = 1885/2794 (67.47%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQG--AQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD-------------PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW----DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKP---------------------GSF---KEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHF-------------------ENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDD---PKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKY--------------FGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQ---NSLENVMPRRRVRDRSNIPAM--LRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPA-KENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWS--DINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGD------------------------------------PEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGD+ SLYAEG+ SGF+STLGLVDDRCVVQP AGDL+NPPKKFRDC F++CPM+R+SAQKQFW A K G + TD++L+NKLH AA+LEK QN+ E+KKL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD+ GNEGSWF +QPFYK ++GDNVV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+C TSW+I LF+++ +N + VLKGGDVVRLFHAEQEKFLTCDE++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE++ D +++R++ R D ++ LVS+P ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDKEE+KP+M ++G + LKEDKEAFAIV VS EVRDLDFAND SKVL+ + K++ TI N+++ V LL +++F+ + S D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELIC + N DIL++T+ L ++ E EEEE+ W D+G + SK+++EL A +D+ ++ YYRYQLNL++ MCLDRQYLAIN +S++L + LIL+C++++ P +LRASFCR+M+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YD+ + +EVK F M FVE YL ++ + FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD I + LD E K G F + + + L+M+TKL+ IEILQFILNVRLD++I+CLLCIFK F + +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VS AL +LFRHF+QRQEVLQ FKQVQLLV++ DVENY+QIK+DLD LR +VEKSELWVYK + S D + +V + H K + PK++ T NY +KEIL RL LC + K++K +QRLL+NMGAH+V++ELLQIP++K D++MQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L+ MM +R +L + L+YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF+ L+D+ +V ++ D LE VT TIM ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK N+ +K + ++ K + I IP +L+ Q+N +K I+ K + +W L+++N ++DS T + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF HTEA KCESGGFI +LIKHT+ LL NEE+LCIKVLQTLR M++ D + +K LRQ L+ +Y FGN V I S K +++ + + R+ ++S +++Q +LD +GAS+L+IDLI++ +S +RVF E I IALLEGGNT +Q SF++RL DK+S+KFF+ F + AQ EIK+ + + GN + N+ + P+RR S + R+QL +A+ + +A + R+ + +E + + + E +S ++I++PI RFLQLLCENH R+LQ+ LR Q NK +YNLVCETLQFLDCICGST+GGLGLLGLYIN+HNV LINQ + +LTEYCQGPCH+NQN IA HESNGIDIIIALILNDINPLGR RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K+A+ + +E E G ASP+ VGHNIYILAHQLS+H +EL LL+PG DQALEYY KHT+QIEIVR DR+ME+IVFP+P IC ++T E+K +V TE DEQGSK+ FF + +F EM+WQK LRA+ +L+W S +M WS+++F +++N+L+ +YP E+ + ++W+ ++ SL + +V + V + ++++ F + + L +G N+ N I+F++S GNRG + + ++ EFL H ++ +LGL H FYS+ L DL+ REETLLNVI+SVT+N RS+VLT +LG+IL Y F+I G++FF+DDF +E + + D + ER CD+L MC+ T L GLR+GGG+GD+LRKPS +E+ F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ K+EIL+ TCFIC L R FDNKTVTFEEH + EHN+WHYL+FIVL++VKD TE+TGPESYV++MIK NLDWFP+ RAMSL + + E EQN+L+SLQ +LE T +++SNL++QLTELK QMTEQRK KQR LL
Sbjct: 7 SFLHIGDVCSLYAEGSTSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGDVVRLFHAEQEKFLTCDEHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLRIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHICRLCYRVLRYSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETK-------------------------LVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAKDGHTEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQLDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDN---DGTSSDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHISTPF-HIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEVKAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKTEFDESNSQSEPSLSPESPASVQGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVYKRQGS------DSGLDAGEVTPEAHHKVRIRSNK--------------PKVESTSSSNYRVVKEILLRLSKLCVLEGISGKKNKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVQMQEIMTLAHQFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRSVHYLKFLQTIVKAENKFIKKCQDIVMAELVTAGEDVLVFYNDRASFQSLVQMMRLERERLDESSALRYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYVDTEVEMKEIYTSNH-MWKLFDDFLVDVCRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPFSDQSTSLQTRQPVFVQLLQGVFRVYHCNWLLPGQKGNVEACIKVLSDVAKGRAIAIPVDLDCQVNNLFMKSNNIVQKTALSWRLSVRNATRRDSVLT--------TSRDYRNIIERLQDIVSALEERLRPLVQAELSVLVDVLHRPELLFPEHTEAHRKCESGGFICKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKGEALRQLLVNRYYGFRSGGRRESLTSFGNSTLTPVGPIKSQPGKYIVTSGSIWGLSRA--EMSLMEVQCHLDREGASDLVIDLIMNTTS-DRVFHESILLAIALLEGGNTIIQHSFFKRLTEDKNSEKFFRVFYDRMKVAQVEIKATVTVNTSDLGNKRRDDNTPDKDTPQRRRGKDSGVVVTDDAREQLLEASAATKKAFGSYRRDAD--------------------PEETFGTADGDKGGGDKGTEQGEMSPVILIMQPILRFLQLLCENHNRDLQNFLRCQN-NKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINQHNVALINQTVESLTEYCQGPCHDNQNCIATHESNGIDIIIALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVMKMAYQQGE--------AEFEDEEQENGEDHAASPRNVGHNIYILAHQLSRHNKELQILLKPGGE----DQALEYYTKHTSQIEIVRQDRTMEQIVFPVPNICSFLTNESKLRVYYGTERDEQGSKINDFFLHADDLFNEMRWQKKLRAQPVLYWCSRNMSFWSNVSFNLAVLINLLVAFFYPLDGVSESQLEPSLSLLLWVCLLGSLGFVLMSPRPNAVRVLVISTVLQLGFSVGLQHMLTLLGAFNVCNKIVFMLSFVGNRGSFTRGYRVMVMDREFLFHLLYLLICILGLFGHVFFYSLLLFDLVNREETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYMFFKDDFILEVNRISNGTLAKAQTSDLLAVRRLFTIIINSCILILKCHKIHCLNPTDCVCFIDDVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMTEQRKHKQRLGLL 2693
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Zebrafish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2]) HSP 1 Score: 2595.46 bits (6726), Expect = 0.000e+0 Identity = 1417/2877 (49.25%), Postives = 1906/2877 (66.25%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDP--------------TP---------DLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQ---SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPM--KVTQLDLDIESQ--------------------KPGSF---KEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENE-----------------------IDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPS-LQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMD-------IEFDD---------------------------------KANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN-------PIVE-EIPRSF---------------DQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLEN-----VMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLR-------------AKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNV---MVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDF-------------QMEPEFLDIISGKIGSDGD--------------------PEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL-RPENWPATNQQ*A 8108
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP +GDL+NPPKKFRDC F++CPM+R+SAQKQFW A K G TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LDS GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N + +LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWE+EVV D CRGGAG W+SLFRFKHLATG YLAAE++ D +P + +R++LR + ++ LVS+P ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDKEE+KP+M ++G + +KEDKEAFAIV V EVRDLDFAND SKVL+ + K++ TI N+++ V LL ++FF+ + ++G D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELIC + + N DIL++T++ +L+ VE + P EEE + W N + SK+++EL A KDD+ +++YYRYQLNL++ MCLDRQYLAI +S +L + LIL+C++++ P +LRASFCRLM+H+HVDRDPQE V PV+YARLW++IP K+ ID+YD+ + ++E+K F M FVE YL ++ N+ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + + +++ ES+ + G F ++ + + ++ L+M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGAL +LFRHF+QRQEVL FKQVQLLV++ DV+NY+QIK+DLD LR VEKSELWVYK + D E SD H K ++S + K D NY +KEIL RL LC + P KS+K +QRLL+NMGAH+V++ELLQIP++K D++MQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L+ MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI +V ++ D LE VT T+M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C+WL QK ++ +K + ++ K++ I IP +L+ Q+N +K +++ TI N + S R S L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFIS+LIKHT+ LL NEE+LCIKVLQTLR M++ D I FDD ++ LRQ L+ +Y+GN +++ L+N P+ + + P +LS ++Q +LD +GAS+L+IDLI++ +S +R+F+E I IALLEGGN +Q+SF+ RL D S+KFF+ F + AQ EIK+ + + +D S+ E+ V R++V+D + I +R+QL +A+ + +A R+ + + E+ N+ E ++ +S + I++PI R +QLLCENH RELQ+ LR Q NK +YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ + +LTEYCQGPCHENQN IA HE NGIDIIIALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + + +V GE G + ASP+ VGHNIYILAHQL++H +EL +L+PG D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K +V TE DEQGSK+ FF + +F EM WQK LR ++ +L+W S +M WS I+F ++MN+L+ +YP + + +++W +++SL + + + + + I+++ F + + P L +G N+ N +IF++S GNRG + + ++ EFL H +I LG+ VH FYS+ L DLI REETLLNVI+SVT+N RS+VLT +L +IL Y F+I G++ F+DDF Q + + ++G + + +KER CD+L MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTVTFEEH + EHNMWHYL+FIVL+KVKD TEFTGPESYV+EMI+ NLDWFP+ RAMSL + + E EQN+++SLQ +LE T ++ISNLS QLTELK QMTEQRKQKQR LL P++ QQ A
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPESGDLNNPPKKFRDCQFRLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKEAILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEIEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEESQESRSSVADFSPFNFQLDSEHEALRARLRTPNEKVMYSLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPIDKEEEKPVMLRIGTSAVKEDKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKLLEDLVFFVVDIPNNGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELNDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICNAVLNPANADILIETKL-----------------------VLSRFEVESGEGPMESEIDEEEVWLF--WKNSNKEVKSKSIRELAQDAKEGQKDDQDVISYYRYQLNLFARMCLDRQYLAIEKISGQLDVDLILRCMSDEDLPYDLRASFCRLMLHMHVDRDPQEQVMPVKYARLWSEIPSKIAIDDYDN---DGTSRDEIKERFALTMDFVENYLRDVVLQNVPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVSTIYPINKMEKGDESKSSNVMKSIHGVGELMTQVVLRGGGFLPTTPTTPPDGDVVKTQTEPEKEDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNTQTDTAPAPNADGPNSIPNIPALDFENIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSNVEKSELWVYKRQGDEGMDGGDGLPAE----SD-HKKKRDSGSDKK-------------KTDGNGSDNYRDVKEILLRLSKLCVQEGPSGKKSKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVRMQEIMKLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAITMQHIFMNNFQLCSEMNERVVQHFVHCIETHGRHVQYLKFLQTIVKAENKFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHKDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRVCNNTSDRKHADTTLESYVTETVMSIVTTFFSSPFSDQSTSLQTRQPVFVQLLQGVFRVYHCSWLLPSQKGSVESCIKVLSDVAKSRAIAIPVDLDSQVNNLFVKSNNVVQK-----TILNWRLSARNASRRDSTLTASKDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFISKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKLIAFDDELDVAELAPPPEPEVPAEEFDPNQPQKQLEDQKRSEALRQVLVNRYYGN--------FKPGGRRDSLTNFSNGPLTPVGQTKTPAGGGGGGGGGGGGSAGSRGELSLAEVQCHLDREGASDLVIDLIMNATS-DRIFQESILLAIALLEGGNPVIQRSFFCRLTGDNKSEKFFKVFYERMKLAQQEIKATVTVNTSDLGSKRKDEDTNDKDVQSRKKVKDVAVITEEVREQLLEASTVTKKAFSTYRREADAD--------------------EHLNATEGPSSTAEKNQDENEMSVIITIMQPILRLMQLLCENHNRELQNFLRCQN-NKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTVESLTEYCQGPCHENQNCIATHECNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEI----EVEHTDDGENGEEEHA--ASPRNVGHNIYILAHQLARHNKELQAMLKPGGTYGEGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPNICEFLTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRGTQEATGNANSVPSQPILYWCSRNMSFWSSISFNLAVLMNLLVAFFYPLEGGGVRGGTLEPHLSALLWAAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTLFLLGAFNVGNKVIFLMSFVGNRGTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFYSLLLFDLIYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIIFKDDFILTVDRISNKTLEQSASKMGEFLAGAVCRKEENCSTETMMDAVGVQSSALVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEFTGPESYVAEMIRDHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLISNLSSQLTELKEQMTEQRKQKQRIGLLGHPQHMNVNPQQPA 2782
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Xenopus
Match: c1qbp (complement component 1, q subcomponent binding protein [Source:Xenbase;Acc:XB-GENE-973232]) HSP 1 Score: 2543.07 bits (6590), Expect = 0.000e+0 Identity = 1397/2770 (50.43%), Postives = 1872/2770 (67.58%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK----DPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW-DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD--------------FSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQI-----------TCLLCIFK-----------AHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHK---NYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAH-------------------------QLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVS----VIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIIS-----GKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL-RPENWPATNQQ*A 8108
SFLH+GDI+SLYAEG+V+GF++TLGLVDDRCVVQP AGDL+NPPKKFRDC F++CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+ D PD ++++ + + L+S+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDK+E+KP+M ++G + +KEDKEAFAIV VS EVRDLDFAND SKVLS + K++ TI N+++ V LL +++F+ + ++G D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T++ FE GV + P + E+EEE+ + W D+ K+ SK+++EL A K+D+ +L YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ ++++K F M FVEEYL ++ F+++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + +TQ+ L + G F + + ++ L+M+TKL+ IEILQ L L + TCLL + + +D I +QAE IF + N +DLD +GG+ FLRVLL+L MH YP +VSGAL +LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK G E E G K ++ NY ++EIL RL LC ++ ++RK +QRLL+NMGAH+V++ELLQIP++K D +MQEI+ +AH FLQ FC GN+ NQ +LHK+ +LFLTPG L EA TM I+ +N +LC+ + E+VVQH+ CIETHG V ++KFLQTI+KA+ ++I+KCQD+V++EL++ G++VLVFYND F L+ MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI ++ D LE VT T+M ++ TFF+SPFS+Q+T ++ +Q + LLQ +FR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK I+ K + +W ++++N ++DS T + R++I+ L D + +LE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESG FI +LI+HT+ LL NEEKLCIKVLQTLR M++ D F DK LR L+ +Y+GN I + ++ E +S D+Q +LD QGAS+L+IDLI++ +S +RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + N+ + L +QL +A++ + +A NS + ++ + G+ + E + +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLGR RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G +G ASP+ VGHNIYILAH QL++H +EL +L+PG D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W S +M WS I+F ++MN+L+ +YPF N H + S ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF+ S GNRG + + ++ EFL H ++ +G+ VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E + L + ++ + + EKE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTVTFEEH + EHNMWHYL+FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL +P + QQ A
Sbjct: 7 SFLHVGDIVSLYAEGSVNGFINTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGASSTTDTVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLADNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVTNPSHIDAEPDGGNARMQMVPEKMMCTLISVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNSPIDKDEEKPVMLRIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLSSIAGKLEKGTITQNERRSVTKLLEELVYFVTGLVNAGQDILEVLVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPANADILIETKL--------------VLSRFE------FEGVASGESP--LETGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDQDVLNYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPFDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GTSRDDIKERFAQTMEFVEEYLRDVVGQRFPFADKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVLLFEGGSNVMRSIHGVGELMTQVVL-----RGGGFLPMTPMAAPEGTIKAQREPEKEDILVMDTKLKIIEILQVSLASFLSLILFMNYLLFTSVFTCLLVYLECTSGLPYLFCSTYVSGTLDFEHIEEQAEGIFGGRKNT-PLDLDDDGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGS----------------------------------GPEEVTEAQAGGKSKKSESTSSYNYRVVREILLRLSKLCVQENTTGRRNRKQQQRLLRNMGAHSVVLELLQIPYEK--DTRMQEIMKIAHEFLQNFCAGNQQNQALLHKHINLFLTPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFAHCIETHGRNVQYIKFLQTIVKAEGRFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERERMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDIC-RVRITSDRKHADIVLERYVTETVMSIVNTFFSSPFSDQSTTLQTRQPVFVQLLQAIFRVYHCNWLLPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNIVQKTAMSWRMSVRNAARRDSVLTASR--------DYRNIIERLQDIVSSLEDRLRPLVQAELSVLVDVLHRPELLFPENTDARKKCESGQFICKLIRHTKLLLEENEEKLCIKVLQTLREMMAKDRGFGDKGEALRVILVNRYYGN--------IRTLSRGE----------------MSLSDVQCHLDKQGASDLVIDLIMNATS-DRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFFDRMKVAQQEIKATVTV----NTSD--------------------LGKQLIEASVATKKAY---------NSFRREADPDDHFSLGEGM-----------MAASEKGRDELEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYLQ----------GEVEFEDGESGEDYAASPRNVGHNIYILAHQVGYLYNKMSLYLLHNAKTLCVSPTQLARHNKELQHMLKPGVQTGEGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKIHDFFQRSEDLFNEMNWQKKLRAQHVLYWCSRNMTFWSSISFNLAVLMNLLVAFFYPFV---NVHGGTLDSRLSGLLWTAMMVSLAIVIVLPKPHGIRALIASTILRLIFSIGLQPTLFLLGAFNVCNKIIFLTSFVGNRGTFTRGYGAMVLDVEFLYHLLYLMICAMGVFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLHNETIFPELSQVTEEEEEEKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMRLVTNLSSQLSELKDQMTEQRKQKQRIGLLGQPAHLNINPQQPA 2603
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Xenopus
Match: c1qbp (complement component 1, q subcomponent binding protein [Source:Xenbase;Acc:XB-GENE-973232]) HSP 1 Score: 2534.98 bits (6569), Expect = 0.000e+0 Identity = 1387/2760 (50.25%), Postives = 1862/2760 (67.46%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK----DPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW-DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD-------------------FSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHK----NYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIK--NKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAH-------------------------QLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVS----VIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIIS---------GKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL-RPENWPATNQQ*A 8108
SFLH+GDI+SLYAEG+V+GF++TLGLVDDRCVVQP AGDL+NPPKKFRDC F++CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+ D PD ++++ + + L+S+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDK+E+KP+M ++G + +KEDKEAFAIV VS EVRDLDFAND SKVLS + K++ TI N+++ V LL +++F+ + ++G D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T E + G +++++ W D+ K+ SK+++EL A K+D+ +L YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ ++++K F M FVEEYL ++ F+++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + +TQ+ L + G F + + ++ L+M+TKL+ IEILQ L L + +F + F + I +QAE IF + +DLD +GG+ FLRVLL+L MH YP +VSGAL +LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK S E+ + H K + + +I L P + NY ++EIL RL LC ++ ++RK +QRLL+NMGAH+V++ELLQIP++K D +MQEI+ +AH FLQ FC GN+ NQ +LHK+ +LFLTPG L EA TM I+ +N +LC+ + E+VVQH+ CIETHG V ++KFLQTI+KA+ ++I+KCQD+V++EL++ G++VLVFYND F L+ MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE VT T+M ++ TFF+SPFS+Q+T ++ ++ LLQ +FR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK I+ K + +W ++++N ++DS T + R++I+ L D + +LE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESG FI +LI+HT+ LL NEEKLCIKVLQTLR M++ D F DK LR L+ +Y+GN I + ++E + S ++S D+Q +LD QGAS+L+IDLI++ +S +RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + L +A +A +K+ NS + ++ + G+ + E + +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLGR RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G +G ASP+ VGHNIYILAH QL++H +EL +L+PG D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W S +M WS I+F ++MN+L+ +YPF N H + S ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF+ S GNRG + + ++ EFL H ++ +G+ VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E + D I ++ + + EKE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTVTFEEH + EHNMWHYL+FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL +P + QQ A
Sbjct: 7 SFLHVGDIVSLYAEGSVNGFINTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGASSTTDTVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLADNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVSGLLKIDAEPDGGNARMQMVPEKMMCTLISVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNSPIDKDEEKPVMLRIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLSSIAGKLEKGTITQNERRSVTKLLEELVYFVTGLVNAGQDILEVLVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPANADILIETN-----------GESPLETGEDEEEVWLF------------------------WRDSNKEIRSKSVRELAQDAKEGQKEDQDVLNYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPFDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GTSRDDIKERFAQTMEFVEEYLRDVVGQRFPFADKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCMCPSPTRFLLSGSNVMRSIHGVGELMTQVVL-----RGGGFLPMTPMAAPEGTIKAQREPEKEDILVMDTKLKIIEILQVSLASFLSLILFMNYLLFTSVFTCLLHIE---EQAEGIFGGRKENTPLDLDDDGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKG-----------SGPEEVTEAQWHV-LKLCIPLTWAHGHDSIYLQETPGKSKKSESTSSYNYRVVREILLRLSKLCVQENTTGRRNRKQQQRLLRNMGAHSVVLELLQIPYEKTEDTRMQEIMKIAHEFLQNFCAGNQQNQALLHKHINLFLTPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFAHCIETHGRNVQYIKFLQTIVKAEGRFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERERMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDIC---RVRIDRKHADIVLERYVTETVMSIVNTFFSSPFSDQSTTLQVCGGWGQIKMLLQAIFRVYHCNWLLPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNIVQKTAMSWRMSVRNAARRDSVLTASR--------DYRNIIERLQDIVSSLEDRLRPLVQAELSVLVDVLHRPELLFPENTDARKKCESGQFICKLIRHTKLLLEENEEKLCIKVLQTLREMMAKDRGFGDKGEALRVILVNRYYGN--------IRPAGRRESGG---IGSGTLSRGEMSLSDVQCHLDKQGASDLVIDLIMNATS-DRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFFDRMKVAQQEIKATVTLI----------------------------------------EASVATKKAY--NSFRREADPDDHFSLGEGM-----------MAASEKGRDELEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYLQ----------GEVEFEDGESGEDYAASPRNVGHNIYILAHQVGYLYNKMSLYLLHNAKTLCVSPTQLARHNKELQHMLKPGVQTGEGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKIHDFFQRSEDLFNEMNWQKKLRAQHVLYWCSRNMTFWSSISFNLAVLMNLLVAFFYPFV---NVHGGTLDSRLSGLLWTAMMVSLAIVIVLPKPHGIRALIASTILRLIFSIGLQPTLFLLGAFNVCNKIIFLTSFVGNRGTFTRGYGAMVLDVEFLYHLLYLMICAMGVFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRSDFIFSIRFNQEELSQVTEEEEEEKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMRLVTNLSSQLSELKDQMTEQRKQKQRIGLLGQPAHLNINPQQPA 2604
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Xenopus
Match: c1qbp (complement component 1, q subcomponent binding protein [Source:Xenbase;Acc:XB-GENE-973232]) HSP 1 Score: 2516.49 bits (6521), Expect = 0.000e+0 Identity = 1389/2771 (50.13%), Postives = 1853/2771 (66.87%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLR-KSGDDDVFC-LVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW-DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAI-------PMKVTQLDLDIESQ---KPGSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQI-----------TCLLCIFK-----------AHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIK-EILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAH-------------------------QLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVS----VIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFL---DIISGKIGSDGDPEKE----------RYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL-RPENWPATNQQ*A 8108
SFLH+GDI+SLYAEG+V+GF++TLGLVDDRCVVQP AGDL+NPPKKFRDC F++CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+ P R + + + C L+S+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDK+E+KP+M ++G + +KEDKEAFAIV VS EVRDLDFAND SKVLS + K++ TI N+++ V LL +++F+ + ++G D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T++ FE GV + P + E+EEE+ + W D+ K+ SK+++EL A K+D+ +L YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ ++++K F M FVEEYL ++ F+++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + M+ ++ +Q + G F + + ++ L+M+TKL+ IEILQ L L + TCLL + + +D I +QAE IF + N +DLD +GG+ FLRVLL+L MH YP +VSGAL +LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK G E E G Y I +IL RL LC ++ ++RK +QRLL+NMGAH+V++ELLQIP++K D +MQEI+ +AH FLQ FC GN+ NQ +LHK+ +LFLTPG L EA TM I+ +N +LC+ + E+VVQH+ CIETHG V ++KFLQTI+KA+ ++I+KCQD+V++EL++ G++VLVFYND F L+ MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI ++ D LE VT T+M ++ TFF+SPFS+Q+T ++ +Q + LLQ +FR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK I+ K + +W ++++N ++DS T + R++I+ L D + +LE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESG FI +LI+HT+ LL NEEKLCIKVLQTLR M++ D+ + L Q + Y + V +I+ L+ P+ E +S D+Q +LD QGAS+L+IDLI++ +S +RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + +D S+ E R + + R+ D + ++A E + +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLGR RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G +G ASP+ VGHNIYILAH QL++H +EL +L+PG D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W S +M WS I+F ++MN+L+ +YPF N H + S ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF+ S GNRG + + ++ EFL H ++ +G+ VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E + L I G+ D + C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTVTFEEH + EHNMWHYL+FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL +P + QQ A
Sbjct: 7 SFLHVGDIVSLYAEGSVNGFINTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGASSTTDTVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLADNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVSASPRRAGYGGNARMQMVPEKMMCTLISVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNSPIDKDEEKPVMLRIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLSSIAGKLEKGTITQNERRSVTKLLEELVYFVTGLVNAGQDILEVLVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPANADILIETKL--------------VLSRFE------FEGVASGESP--LETGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDQDVLNYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPFDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GTSRDDIKERFAQTMEFVEEYLRDVVGQRFPFADKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCQNVLVAGGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAPEGTIKAQREPEKEDILVMDTKLKIIEILQVSLASFLSLILFMNYLLFTSVFTCLLVYLECTSGLPYLFCSTYVSGTLDFEHIEEQAEGIFGGRKNT-PLDLDDDGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGS----------------------------------GPEEVTEAQAGGADKVVITPCYWFISLQILLRLSKLCVQENTTGRRNRKQQQRLLRNMGAHSVVLELLQIPYEK--DTRMQEIMKIAHEFLQNFCAGNQQNQALLHKHINLFLTPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFAHCIETHGRNVQYIKFLQTIVKAEGRFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERERMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDIC-RVRITSDRKHADIVLERYVTETVMSIVNTFFSSPFSDQSTTLQTRQPVFVQLLQAIFRVYHCNWLLPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNIVQKTAMSWRMSVRNAARRDSVLTASR--------DYRNIIERLQDIVSSLEDRLRPLVQAELSVLVDVLHRPELLFPENTDARKKCESGQFICKLIRHTKLLLEENEEKLCIKVLQTLREMMA-----KDRGHSLTQICIPNYV-----QMVTRIS-------LTLPLRGE-------MSLSDVQCHLDKQGASDLVIDLIMNATS-DRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFFDRMKVAQQEIKATVTVNTSDLGSKKRDEEQSERETPHRKRAYNSFRREADPDDHFSLGEGMMAA---------------------------------------SEKGRDELEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYLQ----------GEVEFEDGESGEDYAASPRNVGHNIYILAHQVGYLYNKMSLYLLHNAKTLCVSPTQLARHNKELQHMLKPGVQTGEGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKIHDFFQRSEDLFNEMNWQKKLRAQHVLYWCSRNMTFWSSISFNLAVLMNLLVAFFYPFV---NVHGGTLDSRLSGLLWTAMMVSLAIVIVLPKPHGIRALIASTILRLIFSIGLQPTLFLLGAFNVCNKIIFLTSFVGNRGTFTRGYGAMVLDVEFLYHLLYLMICAMGVFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLHNETIFPGESTCLSDELSQVTEEEEEEKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMRLVTNLSSQLSELKDQMTEQRKQKQRIGLLGQPAHLNINPQQPA 2614
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811]) HSP 1 Score: 2338.92 bits (6060), Expect = 0.000e+0 Identity = 1333/2809 (47.45%), Postives = 1823/2809 (64.90%), Query Frame = 3
Query: 87 ESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ-----TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEID---KDPTPDL----------MRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP----IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW---DNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXX---------------------------XXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHF-------ENEID--------------ISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNK-----LSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALI--AVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQ----------------NDSYT--------------DQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVS-----VIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIG-------------------------SDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPEN 8081
E SFLHIGDI+SLYAEG V GF+STLGLVDDRCVV+P+AGDL NPPKKFRDC F++CPM+R+SAQKQ+W A KQ Q +D LL+ KL AA LE+ QNE E+KK+ G VV+YG+VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPF+K + GDNVVVGDKV LNPVNAGQPLH S+Y+L D+ GCKE+N+++ NTSW+INLF++Y++ M+DVLKGGDVVRLFHAEQEKFLTCDEYK +VFLRTT R +ATSATSS ALWEVEVV+ D CRGGAG W+SL+RFKHLATG YLAAE + K P+ R + +G+ F LV++P ND+ S+FE+DPT ++D VPR+SFVR+++ CT W+ ST++PID +E++PI +G KEDKEAFAIV V E+RDLDFAND S +L+ +++ ++ ND++ LL ++FF+ V ++G + LD+ + + +R+RQKL+REQNILKQIF IL++P E +++++L+DQK+ ++ + RLCYR+L+ SQ+DYRKNQE+IAKQ +MQ QIGY ILAEDTITALLHNNRKLLEKHIT +E+ TF+NL+RK ++ RFL +LSDLC+SN++AIP+TQELICKC+ N DIL+KTE+ K PE + +EE+ +TW +N K++++L A + DE++LTYYRYQL L++ MCLDRQYLAI+ +S +LS+ LI C+A++ P +RASFC LM+H+HVDRDPQE+VTPV++ARLWT+IP + I +YDS N+ ++ K F M FVE+YLNN+ + ++ FS++++NKLT E+V+LA+HLIYFGFY+F + LRL +TLL I+D P + + E + + S + + + K D +N ++M TKL+ +EILQFILNVRLD++I+ LL +FK F +N D + +I + AE +F + +++D EGG++FLRVL+ L M+ YP+++SG+LQ+LF+HF+QRQEVL TFKQVQLL+ST DV+NY+ IK++LD LR +VEKSELWV K S+D +KD H + +++ G + + +NY +K ILE L +C + + RK +QRLLKNM AH V+++LLQ+P++K+ D KM+EIL H FLQ+FC N NQ +LHK+ LFLTPG L EAETM I+ +N +LC+ + E V+QH++ C+ THG V +L FL TIIKA+ +YI+KCQDM+++EL + GD+V+VFYND F ++ MM + R + N PL+YHI LV LLA EGKNVY+EIKC SLL +ED+ +V H C VK +Y+ F+ HCY+DTEVE+K+I++ N +W LF +LD+A KR VD LE+ V ++ I +FFNSPFSE +T ++ QT V+ LLQ+ RL +C WL K ++ ++ + + K++ I +P +L+ ++ + + L+ +++ T K F + + QN + +++++ L D I LE +L+PL++AE+SVLV V PELLF T+AR +CESGGFIS+LI+HT+ L++S EEKLCIKVL+TL+ M+ + ++ N LR+ LL Y NK K+N K E S+ I + D IQ LD +GA+ L+ DLI+ S NE++F+E I I LL+GGNT +Q SFY + D S+KFF+ + + AQ EIKS + + + N L P + + P R +NQ +I + +++ S +K +++D NG E+ + +V+I+EPI RFLQLLCENH +LQ+ LR+Q NKT+YNLVCETLQFLD +CGST+GGLGLLGLYINE NV LI Q L TLTEYCQGPCHENQ+ I HESNGIDII AL+LNDI+PL + RMDLVL+LKDNASKLLLA++ESRHDSENAERILI+L P++LV V K A+ ++ D DV SP+EVGHNIYILA QLS+H + L LL+P + N T + L YYAKHTAQIEIVR DRSME+IVF +P IC+++TEETK +V T TE D+QGSKV FF +++++ EM+WQ+ LR+ L++W S M LW I+F + +N+++ +YP+ E ++ S + W + S+++ R LI ALI++ +YL I P L +G LNL N I+F++S GNRG + + ++ EFL H + ++ +VLGL +H LFYS+ L DLI REETL NVI+SVT+N RS++LT +L +IL Y F+I G LF +DDF ME + L + + D + + ER CDTL MC+ T L GLRNGGG+GDILRKPS E F R+++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTV+FEEH + EHN+W+YLYFIVL++VK+ T++TGPESYV++MIK KNLDWFP+ RAMSL ++E E EQN+++ LQ +L T +++S+L+ QL+ELK QMTEQRK++QR + +N
Sbjct: 3 EMSSFLHIGDIVSLYAEGTVCGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFRVCPMNRYSAQKQYWKA-KQAKQDKEKISDVLLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNAGQPLHASNYELTDNPGCKEVNSLNSNTSWKINLFMQYRDYMEDVLKGGDVVRLFHAEQEKFLTCDEYKSRLHVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEENPAYKGDAPEFKSGSSNAVVSTRPSRKNAGEKIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWIQSTNVPIDVDEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLANFVERLNEGFISQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGVMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRKNREP--RFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTELRPL----------------------------KEMSPEYMSLEYCDEEVWLTWTDKNNDSHEKSIRQLSQEARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEISKQLSVDLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPMAITIKDYDS--NLNDSRDNKKNKFTSTMEFVEDYLNNVVSESMPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDNAADGTAPAFDSTNASLNLDRIGELAEAMFGVGKSTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKVIKSELDRLRTMVEKSELWVDKKGNTGIIGSTDGNKKD---------KKEHVENQDNS---------------GKPVMEKSSENYQIVKGILETLNKMCNGPE-QVRKKQQRLLKNMDAHKVMLDLLQVPYEKE-DTKMKEILKYTHQFLQKFCATNPENQALLHKHLSLFLTPG-----------LQEAETMQHIFLNNYQLCSEIHEAVLQHFIHCLATHGRHVQYLDFLHTIIKAEGKYIKKCQDMIMTELTNAGDDVVVFYNDKASFASMLEMMATAREAIEENSPLKYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVRVVTHEDCITEVKISYVNFVNHCYVDTEVEMKEIYTSNH-IWTLFENFILDMA-RVCNKREKRIVDSTLEKYVLTVVLETIRSFFNSPFSENSTSLQTHQTIVVQLLQSTTRLLECPWLLQQYKVSVEACIRALAMLAKSRSISLPMDLDTHVSSLLNSSSSALQRNQS--TYKTTSTRSFAR--GSATQNQWDYKNIVEKLQDIINILEERLKPLVEAELSVLVDVLQHPELLFAEGTDARLRCESGGFISKLIQHTKNLMSS-EEKLCIKVLRTLQQMLMKKRNYGEQGNMLRRTLLNIYLHNK------KLNP---KGETSDSFA--IAQDQDWAMIASIQCKLDREGATKLVSDLIM-SSKNEKIFQESILLAIRLLDGGNTEIQNSFYNLMKGDNKSEKFFKVLNERMKCAQQEIKSTMSV-----NMNDLGAHEPD---DENAEYPPKGR---------NNQYVIHASTSRAITGGSF---RKGHDVAD--NG--------------------ESNEVGPAVLIMEPILRFLQLLCENHNSDLQNFLRNQT-NKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEKNVALIIQTLETLTEYCQGPCHENQSCIVTHESNGIDIITALVLNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVSVIKKAYMQEEEGDSSDV-----------------SPQEVGHNIYILALQLSRHNKHLQHLLKPVKRIQEEEESISTMLSLNNKQLTQMLKSTTAPVQEEEEDPLAYYAKHTAQIEIVRMDRSMEQIVFSVPSICKFLTEETKHRVFTTTEQDDQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGTISFNLAVFINLIIAFFYPYV--EGTSIGILDSPLISLLFWGMVCFSVMSLFTKRYGFRPLI--VALILRSVYYLGIGPTLYILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDVEFLYHVAYILTSVLGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFIMEVDRLPKATSPMAPNNFAEFCEKDQTDCTVGVTTLDEIEDEEGDVERACDTLLMCIITVLNHGLRNGGGVGDILRKPSKDETLFPARIVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLGSTMRLVSHLTMQLSELKEQMTEQRKRRQRMGFVDVQN 2658
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811]) HSP 1 Score: 2331.21 bits (6040), Expect = 0.000e+0 Identity = 1325/2775 (47.75%), Postives = 1811/2775 (65.26%), Query Frame = 3
Query: 87 ESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ-----TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTP------DLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP----IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW---DNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXX---------------------------XXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHF-------ENEID--------------ISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNK-----LSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALI--AVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQ----------------NDSYT--------------DQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVS-----VIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSD---------------GDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQM 8030
E SFLHIGDI+SLYAEG V GF+STLGLVDDRCVV+P+AGDL NPPKKFRDC F++CPM+R+SAQKQ+W A KQ Q +D LL+ KL AA LE+ QNE E+KK+ G VV+YG+VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPF+K + GDNVVVGDKV LNPVNAGQPLH S+Y+L D+ GCKE+N+++ NTSW+INLF++Y++ M+DVLKGGDVVRLFHAEQEKFLTCDEYK +VFLRTT R +ATSATSS ALWEVEVV+ D CRGGAG W+SL+RFKHLATG YLAAE+ + +L R + +G+ F LV++P ND+ S+FE+DPT ++D VPR+SFVR+++ CT W+ ST++PID +E++PI +G KEDKEAFAIV V E+RDLDFAND S +L+ +++ ++ ND++ LL ++FF+ V ++G + LD+ + + +R+RQKL+REQNILKQIF IL++P E +++++L+DQK+ ++ + RLCYR+L+ SQ+DYRKNQE+IAKQ +MQ QIGY ILAEDTITALLHNNRKLLEKHIT +E+ TF+NL+RK ++ RFL +LSDLC+SN++AIP+TQELICKC+ N DIL+KTE+ K PE + +EE+ +TW +N K++++L A + DE++LTYYRYQL L++ MCLDRQYLAI+ +S +LS+ LI C+A++ P +RASFC LM+H+HVDRDPQE+VTPV++ARLWT+IP + I +YDS N+ ++ K F M FVE+YLNN+ + ++ FS++++NKLT E+V+LA+HLIYFGFY+F + LRL +TLL I+D P + + E + + S + + + K D +N ++M TKL+ +EILQFILNVRLD++I+ LL +FK F +N D + +I + AE +F + +++D EGG++FLRVL+ L M+ YP+++SG+LQ+LF+HF+QRQEVL TFKQVQLL+ST DV+NY+ IK++LD LR +VEKSELWV K S+D +KD +D NS G + + +NY +K ILE L +C + + RK +QRLLKNM AH V+++LLQ+P++K+ D KM+EIL H FLQ+FC N NQ +LHK+ LFLTPG L EAETM I+ +N +LC+ + E V+QH++ C+ THG V +L FL TIIKA+ +YI+KCQDM+++EL + GD+V+VFYND F ++ MM + R + N PL+YHI LV LLA EGKNVY+EIKC SLL +ED+ +V H C VK +Y+ F+ HCY+DTEVE+K+I++ N +W LF +LD+A KR VD LE+ V ++ I +FFNSPFSE +T ++ QT V+ LLQ+ RL +C WL K ++ ++ + + K++ I +P +L+ ++ + + L+ +++ T K F + + QN + +++++ L D I LE +L+PL++AE+SVLV V PELLF T+AR +CESGGFIS+LI+HT+ L++S EEKLCIKVL+TL+ M+ + ++ N LR+ LL Y NK K+N K E S+ I + D IQ LD +GA+ L+ DLI+ S NE++F+E I I LL+GGNT +Q SFY + D S+KFF+ + + AQ EIKS + + + N L P + + P R +NQ +I + +++ S +K +++D NG E+ + +V+I+EPI RFLQLLCENH +LQ+ LR+Q NKT+YNLVCETLQFLD +CGST+GGLGLLGLYINE NV LI Q L TLTEYCQGPCHENQ+ I HESNGIDII AL+LNDI+PL + RMDLVL+LKDNASKLLLA++ESRHDSENAERILI+L P++LV V K A+ ++ D DV SP+EVGHNIYILA QLS+H + L LL+P + N T + L YYAKHTAQIEIVR DRSME+IVF +P IC+++TEETK +V T TE D+QGSKV FF +++++ EM+WQ+ LR+ L++W S M LW I+F + +N+++ +YP+ E ++ S + W + S+++ R LI ALI++ +YL I P L +G LNL N I+F++S GNRG + + ++ EFL H + ++ +VLGL +H LFYS+ L DLI REETL NVI+SVT+N RS++LT +L +IL Y F+I G LF +DDF ME + L + + + G+ + ER CDTL MC+ T L GLRNGGG+GDILRKPS E F R+++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTV+FEEH + EHN+W+YLYFIVL++VK+ T++TGPESYV++MIK KNLDWFP+ RAMSL ++E E EQN+++ LQ +L T +++S+L+ QL+ELK Q+
Sbjct: 3 EMSSFLHIGDIVSLYAEGTVCGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFRVCPMNRYSAQKQYWKA-KQAKQDKEKISDVLLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNAGQPLHASNYELTDNPGCKEVNSLNSNTSWKINLFMQYRDYMEDVLKGGDVVRLFHAEQEKFLTCDEYKSRLHVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLGGAGERRELTRPSRKNAGEKIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWIQSTNVPIDVDEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLANFVERLNEGFISQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGVMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRKNREP--RFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTELRPL----------------------------KEMSPEYMSLEYCDEEVWLTWTDKNNDSHEKSIRQLSQEARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEISKQLSVDLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPMAITIKDYDS--NLNDSRDNKKNKFTSTMEFVEDYLNNVVSESMPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDNAADGTAPAFDSTNASLNLDRIGELAEAMFGVGKSTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKVIKSELDRLRTMVEKSELWVDKKGNTGIIGSTDGNKKDKKENQD-----------NS----------------GKPVMEKSSENYQIVKGILETLNKMCNGPE-QVRKKQQRLLKNMDAHKVMLDLLQVPYEKE-DTKMKEILKYTHQFLQKFCATNPENQALLHKHLSLFLTPG-----------LQEAETMQHIFLNNYQLCSEIHEAVLQHFIHCLATHGRHVQYLDFLHTIIKAEGKYIKKCQDMIMTELTNAGDDVVVFYNDKASFASMLEMMATAREAIEENSPLKYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVRVVTHEDCITEVKISYVNFVNHCYVDTEVEMKEIYTSNH-IWTLFENFILDMA-RVCNKREKRIVDSTLEKYVLTVVLETIRSFFNSPFSENSTSLQTHQTIVVQLLQSTTRLLECPWLLQQYKVSVEACIRALAMLAKSRSISLPMDLDTHVSSLLNSSSSALQRNQS--TYKTTSTRSFAR--GSATQNQWDYKNIVEKLQDIINILEERLKPLVEAELSVLVDVLQHPELLFAEGTDARLRCESGGFISKLIQHTKNLMSS-EEKLCIKVLRTLQQMLMKKRNYGEQGNMLRRTLLNIYLHNK------KLNP---KGETSDSFA--IAQDQDWAMIASIQCKLDREGATKLVSDLIM-SSKNEKIFQESILLAIRLLDGGNTEIQNSFYNLMKGDNKSEKFFKVLNERMKCAQQEIKSTMSV-----NMNDLGAHEPD---DENAEYPPKGR---------NNQYVIHASTSRAITGGSF---RKGHDVAD--NG--------------------ESNEVGPAVLIMEPILRFLQLLCENHNSDLQNFLRNQT-NKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEKNVALIIQTLETLTEYCQGPCHENQSCIVTHESNGIDIITALVLNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVSVIKKAYMQEEEGDSSDV-----------------SPQEVGHNIYILALQLSRHNKHLQHLLKPVKRIQEEEESISTMLSLNNKQLTQMLKSTTAPVQEEEEDPLAYYAKHTAQIEIVRMDRSMEQIVFSVPSICKFLTEETKHRVFTTTEQDDQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGTISFNLAVFINLIIAFFYPYV--EGTSIGILDSPLISLLFWGMVCFSVMSLFTKRYGFRPLI--VALILRSVYYLGIGPTLYILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDVEFLYHVAYILTSVLGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFIMEVDRLPKATSPMAPNNFAEFCEKDQTDCTVGEGDVERACDTLLMCIITVLNHGLRNGGGVGDILRKPSKDETLFPARIVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLGSTMRLVSHLTMQLSELKEQV 2621
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Mouse
Match: Itpr1 (inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]) HSP 1 Score: 2634.75 bits (6828), Expect = 0.000e+0 Identity = 1433/2839 (50.48%), Postives = 1902/2839 (67.00%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK-------------DPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTE-IYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW-DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD----FSAIPM-KVTQLDLDIESQ-----------------KPGSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDK---------------------------------------ANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PI--------------VEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDIISGKIG---------------SDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP AGDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D DP D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + LKEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T+ + R + ED++ + + W D+ K+ SK+++EL A K+D IL+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + P+ K+T+ + + S + G F + + + K ++ ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN I S ++E L++ P+ S ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + ++ S + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE + D+ + G + + +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMI+ +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWL-----------------------FWRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDEPMDGASGENE------HKKTEEGTSKPL-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNIVQKTALNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKQISIDESENAELPQAPEAENSTEELEPSPPLRQLEDHKRGEALRQILVNRYYGN--------IRPSGRRESLTSFGNGPLSPGGPSKPGGGGGGPGSSSTSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--------------------DHYQSGEGTQATTDKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2734
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Mouse
Match: Itpr1 (inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]) HSP 1 Score: 2634.37 bits (6827), Expect = 0.000e+0 Identity = 1433/2840 (50.46%), Postives = 1902/2840 (66.97%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK-------------DPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTE-IYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW-DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD----FSAIPM-KVTQLDLDIESQ-----------------KPGSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDK----------------------------------------ANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PI--------------VEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDIISGKIG---------------SDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP AGDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D DP D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + LKEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T+ + R + ED++ + + W D+ K+ SK+++EL A K+D IL+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + P+ K+T+ + + S + G F + + + K ++ ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN I S ++E L++ P+ S ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + ++ S + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE + D+ + G + + +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMI+ +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWL-----------------------FWRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDEPMDGASGENE------HKKTEEGTSKPL-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNIVQKTALNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKQISIDESENAELPQAPEAENSTEQELEPSPPLRQLEDHKRGEALRQILVNRYYGN--------IRPSGRRESLTSFGNGPLSPGGPSKPGGGGGGPGSSSTSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--------------------DHYQSGEGTQATTDKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2735
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Mouse
Match: Itpr2 (inositol 1,4,5-triphosphate receptor 2 [Source:MGI Symbol;Acc:MGI:99418]) HSP 1 Score: 2519.58 bits (6529), Expect = 0.000e+0 Identity = 1395/2793 (49.95%), Postives = 1857/2793 (66.49%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNA--TKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD----------------PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP----IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMK--------------------------VTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENE---------------------IDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHA-KYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQA--ILKHSKAWLTIKNKKDSQFTQYERPSLQNGL-----ETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYF--GNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLEN-----VMPRRRVRDRS-NIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFP--AKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD--------------------------------IISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
SFL+IGDI+SLYAEG+V+GF+STLGLVDDRCVV P AGDL NPPKKFRDC FK+CPM+R+SAQKQ+W A KQG T++ L+ KL AAELE+ QNE E++KL+G +V+Y VIQLLHIKSNK LTVNKRLPALLEKNAMRVSLD+ GNEGSWF + PF+K + GDN+VVGDKV L PVNAGQPLH S+ +LLD+ GCKE+NAV+CNTSW+I LF+++ +DVLKGGDVVRLFHAEQEKFLTCD+Y+K Q++FLRTT R +ATSATSSKALWE+EVV+ D CRGGAG+W+SLFRFKHLATG YLAAE++ D PTP K R++G+ ++ LVS+P ND+ S+FE+D T R+D VPR+S+VR+++ CT WV ST+IPID EE++P+M K+G KEDKEAFAIV V EVRDLDFAND +KVL+ +K+++ +T N+++ V LL +IFF+ V ++G D LD+ + + +R+RQKL+REQNIL Q+F IL++P E ++++DL DQ++ ++ + RLCYR+L+ SQQDYRKNQEYIAK +MQ QIGY ILAEDTITALLHNNRKLLEKHIT EI TF++L+R+ ++ RFL +LSDLC+SN+ AIP+TQELICK + N DIL++T++ VE E DD DD+ + + ++ K P K ++ L A +K D +LTYYRYQLNL++ MCLDRQYLAIN +S++LS+ LIL+C++++S P +LRASFCRLM+H+HVDRDPQE V PVRYARLWT+IP K+ I YDS + + ++K F M FVEEYL + N F ++E+NKLT E+V+LA++LIYFGFY+F + LRL +TLL ILD PM +TQ+ L S P S ++ + +K +S D T +M+TKL+ IEILQFIL+VRLD++I+ +L I+K F + DI +I QAE +F+ + + LD EGG+ FLRVL++LIMH Y ++SGALQ+LF+HF+QR EVLQ FKQVQLLVS DV+NY+QIKADLD LRL VEKSELWV K S + DV E Q A + N ++ G ++ P+ID NY +KEIL RL LC + K R QRLLKNMGAH+V+++LLQIP++K D KM E++ LAH FLQ FC GN NQ +LHK+ +LFLTPG L EAETM I+ +N LCN + E+VVQH+V CIETHG V +L+FLQTI+KA +Y++KCQDMV++ELI+ G++VL+FYND F L+NMM S+RA+ +GPL YHI LV+LLA TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ F+ HCY+DTEVE+K+I++ N +W LF L+D+A+V T ++ D LE CVT ++M ++ FFNSPFS+ +T ++ Q I LLQ+ FR+Y CTW QK ++ ++ + E+ K +GI IP +L+ Q+N +K+ + + + + W + + P + L + R++I+ L D + +LE Q P+MQAE SVLV V + PELLF ++AR +C G F+S+LI HT+ L+ EEKLCIK+LQTLR M+ F ++ + LR+ LL +YF + +S N + K ++ + +S DIQ LD +GAS L+ID+I+ ++ N+R+F E I GIALLEGGNT Q SFY++L K S+KFF+ + AQ EI+S + + D S+ E+ + PR RVRD S ++ ++ QL +A+ +++A R+ ++ I + G QE ++ +E + E +S ++ I+ PI RFLQLLCENH RELQ+ LR+Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV L+NQ L +LTEYCQGPCHENQ IA HESNGIDIIIALILNDINPLG+ RMDLVL+LK+NASKLLLAI+ESRHDSENAERIL N+ P++LVDV K A+ + D D E G+ G+ SPK+VGHNIYILAHQL++H + L Q+L+PG + D+AL+YYA HTAQIEIVR DR+ME+IVFP+P ICE++T E+K++V TE DEQGSKV FF +T ++ EM+WQK +R LFW S H+ LW I+F + +N+ + ++YPF E + ++W+ + + F + + F+ +++++ + + + P L+ +G NL N I+F++S GNRG + + + + FL H + ++ +LGL VH FYS L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G LF +DDF ME + L S G +G+ ER CDTL MC+ T L QGLRNGGG+GD+LR+PS E F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTV+FEEH + EHNMWHYLYFIVL+KVKDPTE+TGPESYV++MI KNLDWFP+ RAMSL ++E + EQN++++LQ +LE T ++ LS QL ELK QMTEQRK KQR L N P N
Sbjct: 7 SFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQPLHASNVELLDNPGCKEVNAVNCNTSWKITLFMKFSSYREDVLKGGDVVRLFHAEQEKFLTCDDYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVKDGEIPTP----KKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKLENGSITQNERRFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREP--RFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPMESSILPDD--IDDEEVWLYWIDSNKEP--------------------HGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSIT--DSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSVPDAQPIVHPSKQASPGEQEDVT-VMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGDNNDNGDPSASGTPDTLLPSALVPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEK---SGSYENGDVG--EGQAKGGEEANEESNLLSPVQDGAKT-------PQIDSNKGNNYRIVKEILIRLSKLC-VQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEK-TDEKMNEVMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLL-----------EAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNH-IWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQTHQPVFIQLLQSAFRIYNCTWPNPAQKASVESCIRALAEVAKNRGIAIPVDLDSQVNTLFMKNHSSTVQRAAMGW---------RLSARSGPRFKEALGGPAWDYRNIIEKLQDVVASLEQQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRC--GAFMSKLINHTKKLM-EKEEKLCIKILQTLREMLEKKDSFMEEGSTLRRILLNRYFKGDHSISVNGPLSGAYAKTAQVGGSFSGQ-DSDKKGISMSDIQCLLDKEGASELVIDVIV-NTKNDRIFSEGILLGIALLEGGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGSKKREEDSDVMALGPRMRVRDSSLHLREGMKGQLTEASSATSKAYCVYRREMD----------PEIDTMCPG--QEAGSA-------EEKSAEEVTMSPAITIMRPILRFLQLLCENHNRELQNFLRNQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINERNVALVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGD---EEGGDDGV-------SPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPEEGDEALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEFLTRESKYRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPMFSVLLWVAVAICTSMLFFFSKPVGIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNHGVPTMTLSSMMETCQKENCSPTIPSSNTAGEEGEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFL-GSNTPHVNHH 2697
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Mouse
Match: Itpr2 (inositol 1,4,5-triphosphate receptor 2 [Source:MGI Symbol;Acc:MGI:99418]) HSP 1 Score: 2452.94 bits (6356), Expect = 0.000e+0 Identity = 1372/2793 (49.12%), Postives = 1829/2793 (65.49%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNA--TKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD----------------PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP----IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMK--------------------------VTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENE---------------------IDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHA-KYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQA--ILKHSKAWLTIKNKKDSQFTQYERPSLQNGL-----ETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYF--GNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLEN-----VMPRRRVRDRS-NIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFP--AKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD--------------------------------IISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
SFL+IGDI+SLYAEG+V+GF+STLGLVDDRCVV P AGDL NPPKKFRDC FK+CPM+R+SAQKQ+W A KQG T++ L+ KL AAELE+ QNE E++KL+G +V+Y VIQLLHIKSNK LTVNKRLPALLEKNAMRVSLD+ GNEGSWF + PF+K + GDNV NAV+CNTSW+I LF+++ +DVLKGGDVVRLFHAEQEKFLTCD+Y+K Q++FLRTT R +ATSATSSKALWE+EVV+ D CRGGAG+W+SLFRFKHLATG YLAAE++ D PTP K R++G+ ++ LVS+P ND+ S+FE+D T R+D VPR+S+VR+++ CT WV ST+IPID EE++P+M K+G KEDKEAFAIV V EVRDLDFAND +KVL+ +K+++ +T N+++ V LL +IFF+ V ++G D LD+ + + +R+RQKL+REQNIL Q+F IL++P E ++++DL DQ++ ++ + RLCYR+L+ SQQDYRKNQEYIAK +MQ QIGY ILAEDTITALLHNNRKLLEKHIT EI TF++L+R+ ++ RFL +LSDLC+SN+ AIP+TQELICK + N DIL++T++ VE E DD DD+ + + ++ K P K ++ L A +K D +LTYYRYQLNL++ MCLDRQYLAIN +S++LS+ LIL+C++++S P +LRASFCRLM+H+HVDRDPQE V PVRYARLWT+IP K+ I YDS + + ++K F M FVEEYL + N F ++E+NKLT E+V+LA++LIYFGFY+F + LRL +TLL ILD PM +TQ+ L S P S ++ + +K +S D T +M+TKL+ IEILQFIL+VRLD++I+ +L I+K F + DI +I QAE +F+ + + LD EGG+ FLRVL++LIMH Y ++SGALQ+LF+HF+QR EVLQ FKQVQLLVS DV+NY+QIKADLD LRL VEKSELWV K S + DV E Q A + N ++ G ++ P+ID NY +KEIL RL LC + K R QRLLKNMGAH+V+++LLQIP++K D KM E++ LAH FLQ FC GN NQ +LHK+ +LFLTPG L EAETM I+ +N LCN + E+VVQH+V CIETHG V +L+FLQTI+KA +Y++KCQDMV++ELI+ G++VL+FYND F L+NMM S+RA+ +GPL YHI LV+LLA TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ F+ HCY+DTEVE+K+I++ N +W LF L+D+A+V T ++ D LE CVT ++M ++ FFNSPFS+ +T ++ Q I LLQ+ FR+Y CTW QK ++ ++ + E+ K +GI IP +L+ Q+N +K+ + + + + W + + P + L + R++I+ L D + +LE Q P+MQAE SVLV V + PELLF ++AR +C G F+S+LI HT+ L+ EEKLCIK+LQTLR M+ F ++ + LR+ LL +YF + +S N + K ++ + +S DIQ LD +GAS L+ID+I+ ++ N+R+F E I GIALLEGGNT Q SFY++L K S+KFF+ + AQ EI+S + + D S+ E+ + PR RVRD S ++ ++ QL +A+ +++A R+ ++ I + G QE ++ +E + E +S ++ I+ PI RFLQLLCENH RELQ+ LR+Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV L+NQ L +LTEYCQGPCHENQ IA HESNGIDIIIALILNDINPLG+ RMDLVL+LK+NASKLLLAI+ESRHDSENAERIL N+ P++LVDV K A+ + D D E G+ G+ SPK+VGHNIYILAHQL++H + L Q+L+PG + D+AL+YYA HTAQIEIVR DR+ME+IVFP+P ICE++T E+K++V TE DEQGSKV FF +T ++ EM+WQK +R LFW S H+ LW I+F + +N+ + ++YPF E + ++W+ + + F + + F+ +++++ + + + P L+ +G NL N I+F++S GNRG + + + + FL H + ++ +LGL VH FYS L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G LF +DDF ME + L S G +G+ ER CDTL MC+ T L QGLRNGGG+GD+LR+PS E F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTV+FEEH + EHNMWHYLYFIVL+KVKDPTE+TGPESYV++MI KNLDWFP+ RAMSL ++E + EQN++++LQ +LE T ++ LS QL ELK QMTEQRK KQR L N P N
Sbjct: 7 SFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNV---------------------------------NAVNCNTSWKITLFMKFSSYREDVLKGGDVVRLFHAEQEKFLTCDDYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVKDGEIPTP----KKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKLENGSITQNERRFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREP--RFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPMESSILPDD--IDDEEVWLYWIDSNKEP--------------------HGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSIT--DSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSVPDAQPIVHPSKQASPGEQEDVT-VMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGDNNDNGDPSASGTPDTLLPSALVPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEK---SGSYENGDVG--EGQAKGGEEANEESNLLSPVQDGAKT-------PQIDSNKGNNYRIVKEILIRLSKLC-VQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEK-TDEKMNEVMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLL-----------EAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNH-IWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQTHQPVFIQLLQSAFRIYNCTWPNPAQKASVESCIRALAEVAKNRGIAIPVDLDSQVNTLFMKNHSSTVQRAAMGW---------RLSARSGPRFKEALGGPAWDYRNIIEKLQDVVASLEQQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRC--GAFMSKLINHTKKLM-EKEEKLCIKILQTLREMLEKKDSFMEEGSTLRRILLNRYFKGDHSISVNGPLSGAYAKTAQVGGSFSGQ-DSDKKGISMSDIQCLLDKEGASELVIDVIV-NTKNDRIFSEGILLGIALLEGGNTQTQYSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGSKKREEDSDVMALGPRMRVRDSSLHLREGMKGQLTEASSATSKAYCVYRREMD----------PEIDTMCPG--QEAGSA-------EEKSAEEVTMSPAITIMRPILRFLQLLCENHNRELQNFLRNQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINERNVALVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILNDINPLGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPRELVDVMKNAYNQGLECDHGD---EEGGDDGV-------SPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPEEGDEALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEFLTRESKYRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPMFSVLLWVAVAICTSMLFFFSKPVGIRPFLVSVMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNHGVPTMTLSSMMETCQKENCSPTIPSSNTAGEEGEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFL-GSNTPHVNHH 2664
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Mouse
Match: Itpr3 (inositol 1,4,5-triphosphate receptor 3 [Source:MGI Symbol;Acc:MGI:96624]) HSP 1 Score: 2358.56 bits (6111), Expect = 0.000e+0 Identity = 1339/2805 (47.74%), Postives = 1830/2805 (65.24%), Query Frame = 3
Query: 87 ESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNA--TKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEID-------KDPTPDLM----RSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPL----SENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW---DNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQ--------------------LDLDIESQKPGSFKEXXXXXXXXXX----XXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHF---------------------ENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLENVMPRRRVRDRSNI-PAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQ----------------NDSYTDQALE--------------YYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPF--PAKENNHPNVMVSVI-WLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPE--------------------FLDIISGK-------------IGSDGDPEK-ERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPEN 8081
E SFLHIGDI+SLYAEG+V+GF+STLGLVDDRCVV+P+AGDL NPPKKFRDC FK+CPM+R+SAQKQ+W A TKQ + D +L+ KL AA++E+ QN+ E+KK+ G VV+YG+VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD+ GNEGSW +QPF+K + GDNVVVGDKV LNPVNAGQPLH S+Y+L D+ GCKE+N+V+CNTSW+INLF+++++++++VLKGGDVVRLFHAEQEKFLTCDEY+ VFLRTT R +ATSATSS ALWEVEVV+ D CRGGAG W+ L+RFKHLATG YLAAE + DP + R+ R +G+ + LV++P ND+ S+FE+DPT ++D +VPR+S+VR+++ CT W+ ST+ PID EE++PI +G KEDKEAFAIV V E+RDLDFAND S +L+ +K+ ++ ND++ V LL ++FF+ V ++G + LD+ V + +R+RQKL+REQNILKQIF IL++P E +++++L+DQK+ ++ + RLCYR+L+ SQ+DYRKNQE+IAKQ MMQ QIGY ILAEDTITALLHNNRKLLEKHIT +E+ TF++L+RK ++ RFL +LSDLC+SN +AIP+TQELICKC+ N DIL++TE+ R V+ + + ++++ W +N K++++L A + DE++L+YYRYQL L++ MCLDRQYLAI+ +S +L + L+ C+A++ P +LRASFC LM+H+HVDRDPQE+VTPV++ARLWT+IP + I +YDS N +++ K F M FVE+YLNN+ + + F+N E+N LT E+V+LA +LIYFGFY+F + LRL +TLL I+D P + Q + + S+K F SS + SK D ++T++M TKL+ +EILQFILNVRLD++I+ LL +FK F +++ +I +QAE +F +++D EGG++FLRVLL+L MH YP++VSGALQ+LF+HF+QRQE + TFKQVQLL+S DVENY+ IK++LD LR +VEKSELWV DKK S++ ++V + T S E L P +++ +NY +K ILERL +C + + RK +QRLLKNM AH V+++LLQIP+D K+D KM EIL H FLQ+FC GN NQ +LHK+ LFLTPG L EAETM I+ +N +LC+ + E V+QH+V + THG V +L FL T+IKA+ +Y++KCQDM+++EL + GD+V+VFYND HL++MM++ R + + PL YHI LV LLA EGKNVY+EIKC SLL +ED+ +V H C VK AY+ F+ HCY+DTEVE+K+I++ N +W LF LD+A + KR D LE+ V ++ I FF+SPFSE +T ++ QT V+ LLQ+ RL +C WL K ++ ++T+ + K++ IL+P +L+ ++ + + + A + N K + T N + +++I+ L D I+ALE +L+PL+QAE+SVLV + H PELLF +EA +CESGGF+S+LI+HT+ L+ S EEKLC+KVL+TL+ M+ +F D+ N LR+ LL Y N+ S + EL++P + + + ++ Q LD +GA+ L+ DLI + NE++F+E I I LL+GGNT +QKSFY + DK S++FF+ + AQ E KS + + +D SQ PR DR PA + + S++ L+ + L+R G D E A+ N + SV+I+ PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLD +CGST+GGLGLLGLYINE NVGL+ Q L TLTEYCQGPCHENQ I HESNGIDII ALILNDI+PL + RMDLVL+LKDNASKLLLA++ESRHDSENAERILI+L P++LVDV K A+ ++ + +V SP+EVGHNIYILA QLS+H ++L LL+P + N+ Q L+ YY HT+QIEIVR DRSME+IVFP+P IC+++TEETK ++ T TE DEQGSKV FF +++++ EM+WQ+ LR+ L++W S M LW I+F + +NI++ +YP+ A + ++S++ W+ I S +A +F + SV + ALI++ +YL I P L +G LNL N I+F++S GNRG + + ++ EFL H ++ +VLGL H LFYS+ L DLI REETL NVI+SVT+N RS++LT +L +IL Y F+I G LF +DDF +E + F+ SG + D +P+ ER CDTL MC+ T + GLRNGGG+GDILRKPS E F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTV+FEEH + EHNMW+YLYFIVL++VK+ T++TGPESYV++MIK KNLDWFP+ RAMSL + E E EQN+++ LQ +L T +++S+L+ QL ELK QMTEQRK++QR + +N
Sbjct: 3 EMSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYRGKLQVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGLGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPLVRLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREP--RFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTEL--RPVKEMAQSHEYLSIEYSEEEVWLT------------------------WTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISKQLGVELLFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDS--NLNASRDDKKNKFASTMEFVEDYLNNVVSEAVPFANDEKNILTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCIQAPAAMLQAYEEPGGKNVRRSIQGVGHMMSTMVLSRKQSVFGASSLPAGVGVPEQLDRSKFEDNEHTVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSSTATMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLLHLTMHDYPSLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWV-------DKKG---SVKGEEV--------EAGATKDKKERPSDEEGFLQPHGEKSS-ENYQIVKGILERLNKMCGVGE-QMRKKQQRLLKNMDAHKVMLDLLQIPYD-KSDNKMLEILRYTHQFLQKFCAGNPGNQALLHKHLQLFLTPG-----------LLEAETMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKAEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGVEDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVTVVTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNH-IWTLFENFTLDMA-LVCNKREKRLSDPTLEKYVLTVVLDTISAFFSSPFSENSTSLQTHQTIVVQLLQSTTRLLECPWLQQQHKGSVEACVRTLAMVAKSRAILLPMDLDAHMSALLSSGGSC--SAAAQRSAANYKTATRTFPRVIPTANQWDYKNIIEKLQDIIMALEERLKPLVQAELSVLVDMLHWPELLFPEGSEAYQRCESGGFLSKLIRHTKGLMES-EEKLCVKVLRTLQQMLLKKSKFGDRGNQLRKMLLQNYLQNR---------KSGARGELTDPTGSGLDQDWSAIAAT--QCRLDKEGATKLVCDLIT-STKNEKIFQESIGLAIRLLDGGNTEIQKSFYNLMTSDKKSERFFKVLHDRMKRAQQETKSTVAVNMSDLGSQ-------PR---EDREPADPATKGRVSSFSMPSSSRYLLGL--GLHR-----------------GHD------------MSERAQNN-EMGTSVLIMRPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCIVTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVDVIKKAYLQEEERENSEV-----------------SPREVGHNIYILALQLSRHNKQLQHLLKPVRRIQEEEAEGISSMLSLNNKQLSQMLKSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPAICQFLTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRRLRSMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFYPYVEGASTGVLGSPLISLLFWILICFS-IAALFTKR-YSVRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPGNHSRASPLGMPHGAATFMGTCSGDKMDCVSEVSVPEILEEDEEPDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTSQLNELKEQMTEQRKRRQRLGFVDVQN 2666
BLAST of Inositol 1,4,5-trisphosphate receptor vs. UniProt/SwissProt
Match: sp|P11881|ITPR1_MOUSE (Inositol 1,4,5-trisphosphate receptor type 1 OS=Mus musculus OX=10090 GN=Itpr1 PE=1 SV=2) HSP 1 Score: 2634.37 bits (6827), Expect = 0.000e+0 Identity = 1433/2840 (50.46%), Postives = 1902/2840 (66.97%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK-------------DPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTE-IYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW-DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD----FSAIPM-KVTQLDLDIESQ-----------------KPGSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDK----------------------------------------ANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PI--------------VEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDIISGKIG---------------SDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP AGDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D DP D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + LKEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T+ + R + ED++ + + W D+ K+ SK+++EL A K+D IL+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + P+ K+T+ + + S + G F + + + K ++ ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN I S ++E L++ P+ S ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + ++ S + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE + D+ + G + + +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMI+ +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWL-----------------------FWRDSNKEIRSKSVRELAQDAKEGQKEDRDILSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDEPMDGASGENE------HKKTEEGTSKPL-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNIVQKTALNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKQISIDESENAELPQAPEAENSTEQELEPSPPLRQLEDHKRGEALRQILVNRYYGN--------IRPSGRRESLTSFGNGPLSPGGPSKPGGGGGGPGSSSTSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--------------------DHYQSGEGTQATTDKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2735
BLAST of Inositol 1,4,5-trisphosphate receptor vs. UniProt/SwissProt
Match: sp|Q14643|ITPR1_HUMAN (Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3) HSP 1 Score: 2630.51 bits (6817), Expect = 0.000e+0 Identity = 1439/2846 (50.56%), Postives = 1902/2846 (66.83%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK-------------DPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD----FSAIPM------KVTQLDLDIESQKP---------------------GSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDK---------------------------------------ANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PI--------------VEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDII---SGKIGSDGDP------------EKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D DP D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + +KEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T++ FE GV T +EEE + D+ K+ SK+++EL A K+D +L+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + P+ + + + D+E K G F + + + K ++ ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK +I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN + S ++E L++ P+ S ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + + Q E + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF +E PE F D+ SG+ S P +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKL--------------VLSRFE------FEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDETMDGASGENE------HKKTEEGNNKPQ-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGN--------VRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--DHYQPGEGTQATADK------------------AKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2744
BLAST of Inositol 1,4,5-trisphosphate receptor vs. UniProt/SwissProt
Match: sp|P29994|ITPR1_RAT (Inositol 1,4,5-trisphosphate receptor type 1 OS=Rattus norvegicus OX=10116 GN=Itpr1 PE=1 SV=2) HSP 1 Score: 2627.82 bits (6810), Expect = 0.000e+0 Identity = 1432/2841 (50.40%), Postives = 1901/2841 (66.91%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK-------------DPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTE-IYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW-DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD----FSAIPM-KVTQLDLDIESQ-----------------KPGSFKEXXXXXXXXXXXXXXXDA--DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPL-QYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDK----------------------------------------ANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PIVEEIPR--------------SFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME----------PE----------FLDIISGKIG---------------SDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP AGDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D DP D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + LKEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T+ + R + ED++ + + W D+ K+ SK+++EL A K+D +L+YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + P+ K+T+ + + S + G F + + + K ++ ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + + K + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D KMQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK I+ K + W L+ +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN I S ++E L++ P+ P S ++S ++Q +LD +GASNL+IDLI++ SS+ RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + + ++ S + A+++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N R ++LT L +IL Y F+I G+LFF+DDF +E PE + D+ + G + + +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMI+ +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS QL+ELK+QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWL-----------------------FWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDEPMDGASGENE------HKKTEEGTSKPL-------------KHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLFMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSVLEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNIVQKTAMNWRLSARNAARRDS--------VLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKQISIDELENAELPQPPEAENSTEQELEPSPPLRQLEDHKRGEALRQILVNRYYGN--------IRPSGRRESLTSFGNGPLSPGGPSKPGGGGGGPGSGSTSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSD-RVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPD--------------------DHYQSGEGTQATTDKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDG--DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRPIILTAALALILVYLFSIVGYLFFKDDFILEVDRLPNETAGPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPVEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLL 2736
BLAST of Inositol 1,4,5-trisphosphate receptor vs. UniProt/SwissProt
Match: sp|Q9TU34|ITPR1_BOVIN (Inositol 1,4,5-trisphosphate receptor type 1 OS=Bos taurus OX=9913 GN=ITPR1 PE=1 SV=1) HSP 1 Score: 2620.11 bits (6790), Expect = 0.000e+0 Identity = 1417/2797 (50.66%), Postives = 1888/2797 (67.50%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD-------------PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTE-IYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIP--MKVTQLDLDIESQ--------------------KPGSFKEXXXXXXXXXXXXXXXDAD--NTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSN----PI--------------VEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQNSLE---NVMPRRRVRD-RSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME------------------PEFL--DIISGKIG---------------SDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K GA TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N DD+LKGGDVVRLFHAEQEKFLTCDE++K Q+VFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D D P D RS+LR + + V+ LVS+P+ ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+IPIDKEE+KP+M K+G + +KEDKEAFAIV VS EVRDLDFAND SKVL + K++ TI N+++ V LL +++F+ +SG D L++ + +R+RQKL+REQNILKQIFK+L++P ++ + P +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELICK + + N DIL++T+ + R + ED++ + V + K +SK+++EL A K+D +L YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C+++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YDS+ K+E+K F M FVEEYL ++ FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + ++++ E++ + G F + + + + K ++ + + ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLV++ DV+NY+QIK DLD LR +VEKSELWVYK + D+ S + + H K + S + + T NY +KEIL RL LC + KSRK +QRLL+NMGAH V++ELLQIP++K D MQEI+ LAH FLQ FC GN NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V ++KFLQTI+KA+ ++I+KCQDMV++EL++ G++VLVFYND F LI MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+D EVE+K+I++ N MW LF L+DI + ++ D LE+ VT +M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ ++ + ++ K++ I IP +L+ Q+N LK ++ K + W LT +N ++DS L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFI +LIKHT+ LL NEEKLCIKVLQTLR M++ D + +K LRQ L+ +Y+GN I S ++E L++ P+ P S ++S ++Q +LD +GASNL+IDLI++ SS +RVF E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + GN + E + R++ ++ + I +R QL +A+ + +A R+ + D ++ D+ ++++ +S + I++PI RFLQLLCENH R+LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + E E G G ASP+ VGHNIYILAHQL++H +EL +L+P GQ D D+ L++YA+ T EIVR DR+ME+IVFP+P ICE++T+E+K ++ TE DEQGSK+ FF + +F EM WQK LRA+ +L+W + +M WS I+F ++MN+L+ +YPF P+ ++W +++SL + + + + + I+++ F + + P L +G N+ N IIF++S GN G + + ++ EFL H ++ +GL VH FYS+ L DL+ REETLLNVI+SVT+N RS++L +L +IL Y F+I G+LFF+DDF +E EFL D+ + G + + +KE C+TL MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL FIVL+KVKD TE+TGPESYV+EMIK +NLDWFP+ RAMSL + + E EQN+L++LQ +LE T ++++NLS L+ELK+QMT+QRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWVFWRDSNKE--------------------VRSKSVRELAQDAKEGQKEDRDVLGYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPSDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSS---GTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPTATAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEETTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ-GPDEAMDGASGENE------HKKTEEGNNKSQ-------------QHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTMMQEIMRLAHEFLQNFCAGNHPNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDPEVEMKEIYTSNH-MWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNLVQKTAMNWRLTARNAARRDS--------VLPVSRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQILVNRYYGN--------IRPSGRRESLTSFGNGPLSPGGPSKPGGGGGGSGSSPMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASS-DRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPATQITEEVRDQLLEASAATRKAFTTFRR-----EADPDDHYQSGEGAQAAADK---------------SKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQ----------GEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDG--DETLDFYAQPTGPNEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPH-WSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLXLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILMAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETSLPEASESLASEFLYSDVCRVETGENCSSPAPKEELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGLLSELKDQMTDQRKQKQRMGLL 2695
BLAST of Inositol 1,4,5-trisphosphate receptor vs. UniProt/SwissProt
Match: sp|Q8WSR4|ITPR_PATPE (Inositol 1,4,5-trisphosphate receptor OS=Patiria pectinifera OX=7594 GN=IP3R PE=1 SV=1) HSP 1 Score: 2585.45 bits (6700), Expect = 0.000e+0 Identity = 1433/2790 (51.36%), Postives = 1882/2790 (67.46%), Query Frame = 3
Query: 90 SKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQ--GAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTIN-DKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLT--VNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQ-ENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAI-PMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXX---------------------DADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE------NEI----------DISKICQQAEDIFS-EKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERL--IVLCESDDP-KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMV-TEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIK-NKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNK----LSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLENVMPRRRVRDRSNI--------PAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYE---------DTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP-GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIK-ISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME------------------------------PEFLDI---------------ISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWP 8087
S SFLH GDI+SLYAEG+V+GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FKICPM+R++AQKQFW + K + TD++L+ KL AAE+EK QNE E+KKL+G+V+ YG VIQLLHIKS+K +TVNKRLPALLEKNAMRV+LDS+ EGSWF + PFYK + GDNVVVGDKV LNPVNAGQPLH S+Y+L+D+ GCKE+N+V+CNT W+++LF+E+KEN+D LKGGDVVRLFHAEQEKFLTCDEYKK Y+FLRTTGR +AT+ATSSKALWE EVV D CRGGAG W+SLFRFKHLATGQY+AAE+D D T D R KLR V+ +V I ND+ SIFE+DPT D VPRSS+VR+++ CT WVHSTSIP+DK EDKP+M KVG A ++ED+EAFAI+ VS EVRDLDFAND +KVLS + K++ +I +++ V LL+ +++F+ + ++G D L++ V+ DRDRQKL+REQ+ILKQIFKIL++P ++N +KM++L D +H +R+ICRLCYRIL+LSQQ YRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI TF+NL+RK + RFL++LSDLC+SNN AIP+TQELICK + E N DIL++T++ + +E+E E E DD T V +E+ + +++ W NG +SK+++ + N K+D ++L YYRYQL+L+S MCLDRQYLAIN + +L I LI +C++++S P +LRASF RLM+H+HVDRDP+E VTPV+YA LW++IP ++ ID+YD A+ + KE+ + F + FVEEYL N+ + L+ ++EQNKLT E+VNLAKHLIYFGFY+F + LRL KTLL ILD +A+ +LD + K G F+ + + + L+M TKL+ I+ILQFILNVRLD++I+CLL IFK F+ +EI D I +QAE IF ++N D +GG+ FLRVL++L MH Y +VSGALQ+LF+HF+QRQEVL+ FKQ+QLLVS+ DV+NY+QIK DLD LRL VEKSELWVYK + D+ S +++ H K + + K + T NY +KEIL RL +V E + K+RKHEQRLL+NMGA TV++ELLQIP++K +D +M E++ LAH FLQ FC N SNQ +LHK+ DLFLTPG L EA+TM I+ +N +LC+ V E+VVQH+V CI THG V +LKFLQ I+KA QYIRK QDMV++EL++ G++VL+FYND F INMM ++R ++ + P QY + LL + TEGKNVY+EIKCHSLL ++DI + H C VK AY+ FL HCY+DTEVE+K+I++ N +W+LF L+D+A V ++ D LE+ VT T+M +I FF+SPF++Q+T ++ +Q + LLQ FR+ QC WLT QK ++ +KT+ +I K +GI IP +L+ Q+N + ++KH++ WL I N+ R + RS+I+ L D + LE QL+PL+QAE+SVLV V HRPELLF AR KCESG FIS+LIKHTE LL EEKLCIKVLQTL+ M+++DI++ +K LRQ LL++Y+G + V+ P + R+ +++ ++Q LD +GAS+L+IDL+I +SSN RVF E +E GIALLEGGNTN+QKS L DK+S+KFF+ F + EA +EIK+ + + +G Q + +R R P L Q+ + + ++ AL + S V + + G ++ A+E ++S + I++PI RFLQLLCENH RELQ LRHQ NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE+NV LINQ L +LTEYCQG CHENQNAIA HESNG+DII ALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL+N+SPKQLVDV K A+ + + +++ DD + SP+EVGHNIYILAHQL+ H +ELA LL+P G N YTD+ALEYY KHTAQIEIVR DR+ME+IVFP+P++CEY+T ETK KV T+ E D+QGSKV FF +T MF EM+WQK LRA+ +LF S++M WS + F +++N+L+ +YPF + + ++WL + SL A V +R + V A I++ + F + + P LLF+ L + N IFI+S GN G+ K I + E L H +I LGL VH FYS+ LLD++ +E+TL+NVI SVT+N+RS+ T +L +IL Y F+I G+LF QDDF E P L++ +S G + E+ER C+TL M + TTL G+R+GGGIGD+LR PS +E + RV++DL F+ +V +I+LNLIFGVIIDTFA LR KQ+K+EIL+NTCFIC LNRS+FDNK+V+FEEH++ EH+MWHYLYFIVL+KVKDPTEFTGPESYV M K KN DWFP+ RAMSL +DE E EQN+++ LQ++LE T+ ++ LS QL ELK+QMTEQRKQKQR +LL + P
Sbjct: 5 SASFLHFGDIVSLYAEGSVNGFISTLGLVDDRCVVQPDFGDLNNPPKKFRDCLFKICPMNRYTAQKQFWKSAKPNVSSATDAVLLKKLQHAAEMEKKQNETENKKLMGSVIVYGNVIQLLHIKSHKYMTVNKRLPALLEKNAMRVTLDSSATEGSWFYIVPFYKLRSAGDNVVVGDKVVLNPVNAGQPLHPSNYELIDNPGCKEVNSVNCNTCWKVSLFMEHKENLDG-LKGGDVVRLFHAEQEKFLTCDEYKKKSYIFLRTTGRVSATAATSSKALWETEVVQHDPCRGGAGHWNSLFRFKHLATGQYMAAEVDNDNTKDHTREKLRGPHGGTVYQMVPIIHGNDIASIFELDPTTLQGGDSMVPRSSYVRLRHLCTNTWVHSTSIPLDKGEDKPVMLKVGTAQIREDREAFAIIPVSPTEVRDLDFANDANKVLSAIASKLEKSSITQNERFVTQLLTDLVYFVSILPNNGGDALNVVVQNPDRDRQKLMREQDILKQIFKILKAPFTDNGDGAMLKMEELADPRHAPYRHICRLCYRILRLSQQAYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITATEIETFVNLVRKNGEC--RFLEYLSDLCVSNNQAIPVTQELICKSVLVERNSDILIETKLVRTQMEVEME--------VEADDGTTEPVYTIEEEEE------------VVLFWKNGTKSKSIRS-CHGGTENVKEDANVLKYYRYQLDLFSQMCLDRQYLAINQIGPQLDIDLIHRCMSDESLPYDLRASFTRLMLHMHVDRDPKEQVTPVKYAELWSEIPTQITIDDYDGANNLTHAGKEDAQPKFSLTIKFVEEYLCNVVSGVLVVYDKEQNKLTFEVVNLAKHLIYFGFYSFSELLRLTKTLLSILDCTALHGTAPGKLDPKADIGKGGVFRSIHGVGAVMTNMVLGKRLPTPVTRDPAWPLGWGLDNHNKQDELVMETKLKIIQILQFILNVRLDYRISCLLSIFKRDFDESKDSTDEITTSGKVWTASDFEHIEEQAEGIFGGSEENTPLDLDDDDGGRTFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEVLEAFKQLQLLVSSQDVDNYKQIKQDLDQLRL-VEKSELWVYKGQ-GPDEPMDGASGEQE------HKKTEEGTSKPL-------------KHESTSSYNYRVVKEILLRLSKLVCVEGNGTRKNRKHEQRLLRNMGAFTVVLELLQIPYEKNHDTRMNELMRLAHEFLQNFCWANPSNQVLLHKHIDLFLTPGLL-----------EAQTMCHIFMNNFQLCSEVTEQVVQHFVHCIATHGRHVQYLKFLQAIVKADGQYIRKTQDMVMAELVNAGEDVLLFYNDKASFQMFINMMRTERERMDASSPSQYRHQPWTLLGLACTEGKNVYTEIKCHSLLPLDDIVRVATHEDCLPEVKNAYINFLNHCYVDTEVEMKEIYTSNH-VWNLFENFLVDMAMVCNATHDRKHHDHMLEKTVTETVMNIITMFFSSPFADQSTTVQTRQPVFVRLLQGAFRVSQCDWLTGHQKYHVENCIKTLTDIAKNRGIAIPVDLDSQVNT-LFSKSIVMKHTRHWLAINPNRSRDSMVAISR-------DYRSIIEGLQDIVSLLEDQLRPLVQAELSVLVDVLHRPELLFPFRHRARQKCESGAFISKLIKHTEKLLEEKEEKLCIKVLQTLKEMMTVDIDYSEKGEDLRQCLLLRYYGKSHLRMKHRGVVASGRGQTNVTSCGPGSRVLSRA--EMTLAEVQCQLDKEGASSLVIDLVIKNSSN-RVFLESVELGIALLEGGNTNIQKSIINCLMSDKNSEKFFKVFFDRMREA-SEIKATVTVNTGEGIGQTKPTEGRNGQHLRRRLTWPHEKGWTRPQRLNQRRAEDQLLADAALHTSKASRQSARVATTTLLASCQVLAGGAEK---------------AKEEEKMSMEIAIMQPILRFLQLLCENHNRELQSYLRHQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINENNVALINQTLESLTEYCQGACHENQNAIANHESNGLDIITALILNDINPLGKNRMDLVLELKNNASKLLLAIMESRHDSENAERILLNMSPKQLVDVIKQAYQQEDLERDDDDELIIEEDD---------------EAISPREVGHNIYILAHQLAHHNKELAALLKPTGPNSEYTDRALEYYFKHTAQIEIVRQDRTMEQIVFPVPQLCEYLTAETKIKVFTKAERDDQGSKVADFFEKTEDMFMEMKWQKKLRAQPILFLASSNMSKWSLVCFNLAVIVNLLVAFFYPFDVTTTELDHGLSMLVWL-MAASLAAIVTLRRPSGIRPLVFATILRMLIFSIGVEPTLLFLAVLTIFNKCIFILSFLGNCGLLYKGVRGIFTDMEVLYHILYLIICFLGLFVHEFFYSLLLLDVVYQEDTLINVIHSVTRNWRSIAFTALLALILVYLFSIVGYLFLQDDFVYEVNPLRPAIATATATNKTGTSPPMPLPPESCPAGLEMEDCLKNNLSHVQAKEVSYDSGIEVGTERERACETLIMYIITTLNFGVRSGGGIGDVLRSPSTREPLYMARVIYDLLFFIVVIIIVLNLIFGVIIDTFADLRSEKQQKEEILKNTCFICGLNRSSFDNKSVSFEEHYKEEHSMWHYLYFIVLVKVKDPTEFTGPESYVYNMTKEKNQDWFPRMRAMSLDSDEGESEQNEMRILQNQLENTNSLVKVLSGQLRELKDQMTEQRKQKQRINLLSSPSIP 2693
BLAST of Inositol 1,4,5-trisphosphate receptor vs. TrEMBL
Match: R9S1J3 (Inositol 1,4,5-trisphosphate receptor OS=Dugesia japonica OX=6161 PE=2 SV=1) HSP 1 Score: 4766.45 bits (12362), Expect = 0.000e+0 Identity = 2413/2682 (89.97%), Postives = 2542/2682 (94.78%), Query Frame = 3
Query: 75 MNNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXX-XXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE---NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLS-KNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN-HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
M NIESKSFLHIGDIISLYAEG+VSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQG+QTDSLLINKLHSAAELEKTQN+IEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVS+YDLLDHVGCKE+NAVSCNTSWQINLFLEYKENM+DVLKGGDVVRLFHAEQEKFLTCDEYKK+QYVFLRTTGRTTATSATSSKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEID DPT DLMR KLRKS DDDVFCLVSIPQSNDVTSIFEIDPTICTRSDD+VPRSSFVRMKNFC GAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVI+FLCSVEDSGSDPLDLEVKEI+RDRQKLLREQNILKQIFKILESPLSENFPIKMDDL DQK+VIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGIL+EDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSS+RFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRI EIEYEV D +DDDLL+V+ EK K ETI ETEEE+EI++TWDNGKQSK+LQELVNA+ NSKD+ESILTYYRYQLNLYSNMCLDRQYLAINYLS+ELSIYLILKCI+N+SFPQNLRASFCRLMIHLHVDRDPQEIV PVRYARLWTDIPK M+IDNYDSADQE+ QKE VK +FGPVM+FVEEYLN+IA+ NLMF++QE NKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDF IPMK+ LDLDI+SQKP +FKESSNSLI+NK++SK+SD DNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE N+IDISKICQQ+EDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQ QLLVST+DVENYRQIK DLD LRLLVEKSELWVYKNKLSSDKKRKD S+ E+Q+ +D+ KYK SV+ S IG ESAIELDLGPKI Q+CHKNYVTIKEILERLI LCESDD KSRKHEQRLLKNMGAH+VIIELLQIPFDKKND+KM EIL LAHVFLQRFC GNESNQ VLHK N+LFLTPG LHEAETMSAIYKDN+KLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIK QDQYIRKCQDMVISELISVGDEVLVFYND+LKF HL+NMMESQRAQLL NGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICN++C+PSCT+ VKEAYLMFLCHCYIDTEVEIKDIFS NSP+WDL N LDIAKV+TTVVSKRSVDKELEECVTHTIM V+VTFFNSPFSEQNT I+NK+ EV+HL+QN+FRLYQCTWLT Q+NNI+FS+KTV+EIIKAKGI+IPF+LEHQ+NKH+LKDQA+LKHSK WL KNKKDSQ Q ERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLV VFHRPELLFLPHTEAR+KCESGGFISRLIKH +CLL SNEEKLCIKVLQTLRMMVSMDIEF++KAN LRQKLL KYFGNK+S + N++ KKEE N +EEIP+ DQLSFVDIQDYLD+QGASNLIIDLII+HSSNERVFREII+FGIALLEGGN+NVQKSFYERLCHDKSSDKFFQAFS++I+EAQN+IKSMIILAADGNSQNSLENVMPRRRVRDRSNIP+MLRQQLDDAA+ESNQALIAVRK+LN+N++ ++Q EN S G DQ+ T++ ISNVF KE+ EENYRLSNSV+IIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSGGLGLLGLYINE NVGLINQ LRTLTEYCQGPCHENQNAIAQHESNGIDIIIALILNDINPLGR RMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLD DD+P+ES+GET GRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEY+TEETKFK+KTQTELDEQGSKVPGFF+ET YMFQEMQWQKSLRAKSLLFW+SNHM+LWSDINFFF+LVMNILLIIWYPFPAK+NN H +VMVS+IWLFI+LSLV TVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNI+FIISLWGNRGIAKKSWS+INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD++SG+IGSDGD +ERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKE FFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLI+VKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQ +LEFTDQIISNLSDQL ELKNQMTEQRKQKQRYSLLRPENWP NQQ
Sbjct: 1 MINIESKSFLHIGDIISLYAEGSVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGSQTDSLLINKLHSAAELEKTQNDIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSNYDLLDHVGCKEVNAVSCNTSWQINLFLEYKENMEDVLKGGDVVRLFHAEQEKFLTCDEYKKEQYVFLRTTGRTTATSATSSKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDTDPTQDLMRMKLRKSEDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDHVPRSSFVRMKNFCIGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIYFLCSVEDSGSDPLDLEVKEINRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLADQKNVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILSEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSYRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRITEIEYEVGPSFDDGFEDDDDLLSVSETEKCKDSETILETEEEDEIVLTWDNGKQSKSLQELVNASANNSKDEESILTYYRYQLNLYSNMCLDRQYLAINYLSNELSIYLILKCISNESFPQNLRASFCRLMIHLHVDRDPQEIVIPVRYARLWTDIPKNMNIDNYDSADQESGQKEVVKQSFGPVMVFVEEYLNSIASCNLMFNDQELNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFGGIPMKIASLDLDIDSQKPPTFKESSNSLILNKVTSKSSDVDNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENGNNDIDISKICQQSEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQAQLLVSTSDVENYRQIKPDLDNLRLLVEKSELWVYKNKLSSDKKRKDTSVSEEQLSTDVSTKYKTSVSTSFIGNESAIELDLGPKIQQSCHKNYVTIKEILERLIGLCESDDMKSRKHEQRLLKNMGAHSVIIELLQIPFDKKNDVKMLEILGLAHVFLQRFCRGNESNQLVLHKYNELFLTPG-----------LHEAETMSAIYKDNLKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKVQDQYIRKCQDMVISELISVGDEVLVFYNDELKFEHLVNMMESQRAQLLSNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNVICYPSCTISVKEAYLMFLCHCYIDTEVEIKDIFSTNSPVWDLLNVFSLDIAKVATTVVSKRSVDKELEECVTHTIMSVLVTFFNSPFSEQNTGIQNKRKEVLHLIQNMFRLYQCTWLTIVQRNNISFSLKTVMEIIKAKGIVIPFDLEHQMNKHILKDQAVLKHSKTWLNAKNKKDSQSNQSERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVSVFHRPELLFLPHTEARNKCESGGFISRLIKHPKCLLASNEEKLCIKVLQTLRMMVSMDIEFEEKANLLRQKLLTKYFGNKMSKNVLKVKNNNNKKEEQINSNIEEIPKPIDQLSFVDIQDYLDAQGASNLIIDLIINHSSNERVFREIIDFGIALLEGGNSNVQKSFYERLCHDKSSDKFFQAFSNNISEAQNDIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPSMLRQQLDDAAVESNQALIAVRKNLNKNTMCLNQM-ENGS----GTDQDATSAPISNVFAKEVNEENYRLSNSVMIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSGGLGLLGLYINEQNVGLINQTLRTLTEYCQGPCHENQNAIAQHESNGIDIIIALILNDINPLGRRRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDADDMPAESAGETSSIGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYLTEETKFKIKTQTELDEQGSKVPGFFTETTYMFQEMQWQKSLRAKSLLFWLSNHMILWSDINFFFSLVMNILLIIWYPFPAKDNNQHGSVMVSIIWLFILLSLVTTVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIVFIISLWGNRGIAKKSWSEINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDLLSGQIGSDGDSGRERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKENFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIRVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQVKLEFTDQIISNLSDQLAELKNQMTEQRKQKQRYSLLRPENWPTNNQQ 2666
BLAST of Inositol 1,4,5-trisphosphate receptor vs. TrEMBL
Match: A0A4Y2F2N2 (Inositol 1,4,5-trisphosphate receptor type 1 OS=Araneus ventricosus OX=182803 GN=ITPR1_3 PE=4 SV=1) HSP 1 Score: 2786.52 bits (7222), Expect = 0.000e+0 Identity = 1514/2815 (53.78%), Postives = 1961/2815 (69.66%), Query Frame = 3
Query: 90 SKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGA--QTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVED--SGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFPI-KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELV-NAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDF----SAIPMKVTQLDLD---------------IESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENE--------------------IDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRK-----DVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLET-RSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSK--NVLKINSSTKKEELSNPIVE---EIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAA------DGNSQNSLENVMPR--RRVRD--RSNIPAM---LRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEI-----AEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP--GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEF--LIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDI-ISGKIG---------------SDG------------------DPEK-------------------------ERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
S SFLHIGDI+SLYAEGNV GF+STLGLVDDRCVVQP AGDL +PPKKFRDC F++CPMSR+SAQKQF A KQ A TD++L+ KLH AAELEK QNE E+KKL+GTV+QYG V+QLLH+KSNK LTVNKRLPALLEKNAMRV LDS GNEGSWF + PFYK + GDNVVVGDKV L PVNAGQPLH S+Y+L D+ GCKE+NAV+ NTSW+I+LF+EYKEN+DDVLKGGDVVRLFHAEQEKFLT D+YKK+QYVFLR+TGRTTAT+ATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D D TPD+MR+KLR + ++V+CLV++P S D+ SIFE+D T TR DD VP+SS+VR+++ CT WVHST+IPIDKEE++P+M KVGCA +KEDKEAFAIV VSA EVRDLDFAND KVL ++ ++ I N+++ V LL VI+F+ E+ DPLDL V +R+RQKLLREQNILKQ+FKIL++P ++ + PI +M++L+D +H F++ICRLCYRIL+LSQQDYRKNQEYIAK MQKQIGY +LAEDTITALLH+NRKLLEKHIT +EI TF++L+RK +S RFL +LSDLCISN VAIPITQELICK + N DIL++T + + E + ++T+ E ++ WDNG++SK+++EL AANGN K+D++IL+YYR+QL+L+S MCLDRQYLAIN LS L I LI KC+A+++ P +LRA+FCRLM+H+HVDRDPQE +TPV+YARLW+DI +K+ I +YD+ + KE V+ F P + FVE+YL N+ + F+++EQNKLT E+V LA+ LIYFGFY+F D LRL KTLL ILD S + K+T DLD + + G+ + + + + A++TL+M+TKL+ IEILQFILNVRLD++IT LL IFK F+ ID+ +I AE IF KD+ EIDLDG+GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLVS +DVENY+QIK+DLD LRLLVEKSELWV+K+K K+K D ++++ K N SAI+LD+GP +D +KNY TI++IL RL LC + P K RKHEQRLL+NMGAH VI+ELLQIP+DKK DI+M E++ LAH FLQ FC N +NQ +LHK DLF+ PG L EA+TM +I+ DN+ LCN + ++VVQH+V CIETHG V +LKFLQTI+KA+ QYIRKCQDMV+ E+++ ++VLVFYND F HL+ MM S+R ++ GPLQYHI LVKLLA TEGKNV++EIKCHSLLS++DI +V HP C VKEAY+ FL HC+IDTEVE+K+I++ N +W LF L+D+A V +R D LE +T+++M +I TFFNSPFS+Q+T ++ Q + LLQ FRL C WL+ Q+ N+ +KT+ +I K +GI IP +L+ Q+ K+ I KH++AWL+ + T PS N + RS+I+ L D + LE QL PL+Q+E+SVLV V HRPELLF P TEAR KCE+GGFIS+LI HTE LL EEKLCIKVLQTL+ M+S+D ++ +K LRQ LL +YFG SK +++ + + + PI + + +++ ++Q +LD +GASNL+++LI+ + SN +F E +E GIALLEGGN +QKS +L S+KFF+ F + +AQ EIKS + + G+ ++++ + + RR++ + N M L++QL+DAA +++A VR + + SD++N +T+ + + ++ AEEN +L V++++PI RFLQLLCENH +LQ+ LR+Q NKT+YNLV ETL FLDCICGST+GGLGLLGLYINEHNV L++Q L TLTEYCQGPCHENQN IA HESNGIDIIIALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESR DSENAERIL N+SPKQLV+VA A++++ E + D SPKEVGHNIYIL HQL++H +ELA +L+P DS +QAL+YYA HTAQIEIVR DR+ME+IVFP+P+ICE++T E+K +V + E DEQGSKV FF T+ +F EM+WQK LR + LL+W+S HM +WS I F +++NI++ I+YPFP + ++W + SL A + + T + I+V + I+++ + + + P L +G +N++ + ++S+ GN G KS+ I ++F L H ++ +LGL HP FYSV LLD++ +EETL NVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF ME + I ++G IG +DG PE+ ER CD+L MC+ TTL QGLRNGGGIGD+LR PS KE F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+NTCFIC L+R++FDNKTV+FEEH R EHNMWHYLYFIVL+ VKDPTEFTGPESYV+ MIK +NLDWFP+ RAMSLAADE E EQN++++LQ +LE T +++S LS QL ELK+QMTEQRKQKQR LL P + Q
Sbjct: 3 SASFLHIGDIVSLYAEGNVCGFLSTLGLVDDRCVVQPDAGDLASPPKKFRDCLFRMCPMSRYSAQKQFLKAAKQSATSATDAVLLKKLHHAAELEKKQNESENKKLIGTVMQYGGVMQLLHLKSNKYLTVNKRLPALLEKNAMRVCLDSAGNEGSWFYIVPFYKLRSSGDNVVVGDKVVLTPVNAGQPLHASNYELQDNPGCKEVNAVNSNTSWKISLFMEYKENIDDVLKGGDVVRLFHAEQEKFLTMDDYKKNQYVFLRSTGRTTATAATSSKALWEVEVVQHDPCRGGAGHWNSLFRFKHLATGHYLAAEVDNDDTPDVMRNKLRGNASNNVYCLVAVPHSTDIASIFELDATTLTRGDDLVPQSSYVRLRHLCTNTWVHSTTIPIDKEEERPVMSKVGCAPIKEDKEAFAIVPVSATEVRDLDFANDACKVLDSISGSLEKGQIIQNERRFVTQLLCEVIYFVAMKENDPKKPDPLDLIVSHPNRERQKLLREQNILKQLFKILQAPFNDCGDGPILRMEELSDPRHAPFKHICRLCYRILRLSQQDYRKNQEYIAKWFGFMQKQIGYDVLAEDTITALLHSNRKLLEKHITAAEIETFVSLVRKNHES--RFLDYLSDLCISNKVAIPITQELICKAVLSPKNSDILIETRMVR---TQLEVEVEVESQNGEVEPMVTIEEEEDV---------------VLFWDNGRKSKSIRELAPGAANGN-KEDQNILSYYRHQLDLFSGMCLDRQYLAINNLSPHLDIDLIQKCMADENLPFDLRAAFCRLMLHMHVDRDPQEQITPVKYARLWSDITQKLSIQDYDANKHPDPNKEAVRAKFAPTIAFVEDYLCNVVGHMWSFADREQNKLTFEVVKLARELIYFGFYSFSDLLRLTKTLLSILDCVPESSFLNGKLTAADLDARGGVLKSIGDMGAVMTNMVLGTSGMTKQVSATMQKKASITGAEDTLVMDTKLKIIEILQFILNVRLDYRITGLLSIFKREFDESQDKSSSDDNSVNIEDKGTSGIDLERISYHAESIFGGKDDCTEIDLDGQGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVSASDVENYKQIKSDLDELRLLVEKSELWVFKSKQEETSKKKKSADDDGDGEQERKKVSKAKKKANLDLGPAGNEGSAIDLDIGPPVDPVQNKNYKTIQQILLRLTRLCVQEMPNGKKPRKHEQRLLRNMGAHAVILELLQIPYDKKEDIRMNELMRLAHEFLQHFCLDNHANQALLHKYIDLFMNPGLL-----------EAQTMRSIFMDNVSLCNELNDRVVQHFVHCIETHGRHVQYLKFLQTIVKAEGQYIRKCQDMVMQEMVNASEDVLVFYNDKTSFNHLVEMMRSERQRMDEAGPLQYHINLVKLLACCTEGKNVFTEIKCHSLLSLDDIVQVVTHPDCLPEVKEAYINFLSHCFIDTEVEMKEIYTSNH-IWTLFENFLVDMAMVCNATHDRRHADVALENYITNSVMNIITTFFNSPFSDQSTTVQTHQPVFVRLLQGAFRLSNCPWLSVHQRMNVESCIKTLSDIGKNRGIAIPVDLDTQVAAMFNKNAMISKHTRAWLS------AARTPRRVPSSTNVFKNDRSIIEGLQDIVSLLEDQLHPLVQSELSVLVDVLHRPELLFPPGTEARKKCENGGFISKLISHTERLLEEKEEKLCIKVLQTLKEMMSLDPDYGEKGEALRQTLLQRYFGKVQSKRDSIVNGKQALHPPKAATPITHGPGGVILTRAEMTLAEVQCHLDEEGASNLVVELIMKNPSNA-IFLESVELGIALLEGGNPVIQKSMLLKLTSGNISEKFFKVFYDKMKDAQQEIKSSVTVNTVELTNRTGDEKDTIGKDLGKDGRRIKTGLKQNGLVMTDELKEQLEDAAAATSKAYAHVRNLGTTGAAAAATE----SDLLNLGQGTHTHVALEEILAEKAEKAKDAEEN-KLPQEVVVMQPILRFLQLLCENHNYDLQNFLRNQN-NKTNYNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVSLVDQTLETLTEYCQGPCHENQNCIAVHESNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRGDSENAERILYNMSPKQLVEVACNAYHQEGED------EEDEDSEEVAEMDDGVSPKEVGHNIYILCHQLAQHNKELAAMLKPNLADPDSKMNQALQYYASHTAQIEIVRHDRTMEQIVFPVPQICEFLTRESKMQVYLKAERDEQGSKVSDFFERTDDLFNEMKWQKKLRGQPLLYWVSRHMSMWSTIAFNLAVLVNIIVAIFYPFPDFSGKIDPRLSGLMWTVMFASLAAVITVPGTTVIRIYVFSSILRMIYSVGLQPTLWILGTVNVVVTAVHLVSIMGNHGTFTKSFRQILTDFELLYHMVYLLFCILGLCAHPFFYSVLLLDVVYQEETLKNVIKSVTRNGRSIILTAVLALILVYLFSIIGYLFFRDDFLMEVDVKHIDLAGAIGVEENANNVSSEPFLSADGYCPADDTACQNRVENIYKSPEQNETVFEVQKVTPSENDDDDDDDTTPERACDSLLMCIVTTLNQGLRNGGGIGDVLRPPSAKEPLFVARVIYDLLFFFVVIIIVLNLIFGVIIDTFADLRSEKQQKEEILKNTCFICGLDRASFDNKTVSFEEHIRCEHNMWHYLYFIVLVIVKDPTEFTGPESYVASMIKDRNLDWFPRMRAMSLAADEAEGEQNEIRTLQVQLENTQKLVSTLSHQLAELKDQMTEQRKQKQRLGLLGTPPVPGSYHQ 2765
BLAST of Inositol 1,4,5-trisphosphate receptor vs. TrEMBL
Match: A0A4Y2EYH5 (Inositol 1,4,5-trisphosphate receptor type 1 OS=Araneus ventricosus OX=182803 GN=ITPR1_3 PE=4 SV=1) HSP 1 Score: 2781.13 bits (7208), Expect = 0.000e+0 Identity = 1514/2815 (53.78%), Postives = 1960/2815 (69.63%), Query Frame = 3
Query: 90 SKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGA--QTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVED--SGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFPI-KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELV-NAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDF----SAIPMKVTQLDLD---------------IESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENE--------------------IDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRK-----DVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLET-RSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSK--NVLKINSSTKKEELSNPIVE---EIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAA------DGNSQNSLENVMPR--RRVRD--RSNIPAM---LRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEI-----AEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP--GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEF--LIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDI-ISGKIG---------------SDG------------------DPEK-------------------------ERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
S SFLHIGDI+SLYAEGNV GF+STLGLVDDRCVVQP AGDL +PPKKFRDC F++CPMSR+SAQKQF A KQ A TD++L+ KLH AAELEK QNE E+KKL+GTV+QYG V+QLLH+KSNK LTVNKRLPALLEKNAMRV LDS GNEGSWF + PFYK + GDNVVVGDKV L PVNAGQPLH S+Y+L D+ GCKE+NAV+ NTSW+I+LF+EYKEN+DDVLKGGDVVRLFHAEQEKFLT D+YKK+QYVFLR+TGRTTAT+ATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D D TPD+MR+KLR + ++V+CLV++P S D+ SIFE+D T TR DD VP+SS+VR+++ CT WVHST+IPIDKEE++P+M KVGCA +KEDKEAFAIV VSA EVRDLDFAND KVL ++ ++ I N+++ V LL VI+F+ E+ DPLDL V +R+RQKLLREQNILKQ+FKIL++P ++ + PI +M++L+D +H F++ICRLCYRIL+LSQQDYRKNQEYIAK MQKQIGY +LAEDTITALLH+NRKLLEKHIT +EI TF++L+RK +S RFL +LSDLCISN VAIPITQELICK + N DIL++T + + E + ++T+ E ++ WDNG++SK+++EL AANGN K+D++IL+YYR+QL+L+S MCLDRQYLAIN LS L I LI KC+A+++ P +LRA+FCRLM+H+HVDRDPQE +TPV+YARLW+DI +K+ I +YD+ + KE V+ F P + FVE+YL N+ + F+++EQNKLT E+V LA+ LIYFGFY+F D LRL KTLL ILD S + K+T DLD + + G+ + + + + A++TL+M+TKL+ IEILQFILNVRLD++IT LL IFK F+ ID+ +I AE IF KD+ EIDLDG+GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLVS +DVENY+QIK+DLD LRLLVEKSELWV+K+K K+K D ++++ K N SAI+LD+GP +D +KNY TI++IL RL LC + P K RKHEQRLL+NMGAH VI+ELLQIP+DKK DI+M E++ LAH FLQ FC N +NQ +LHK DLF+ PG L EA+TM +I+ DN+ LCN + ++VVQH+V CIETHG V +LKFLQTI+KA+ QYIRKCQDMV+ E+++ ++VLVFYND F HL+ MM S+R ++ GPLQYHI LVKLLA TEGKNV++EIKCHSLLS++DI +V HP C VKEAY+ FL HC+IDTEVE+K+I++ N +W LF L+D+A V +R D LE +T+++M +I TFFNSPFS+Q+T + Q + LLQ FRL C WL+ Q+ N+ +KT+ +I K +GI IP +L+ Q+ K+ I KH++AWL+ + T PS N + RS+I+ L D + LE QL PL+Q+E+SVLV V HRPELLF P TEAR KCE+GGFIS+LI HTE LL EEKLCIKVLQTL+ M+S+D ++ +K LRQ LL +YFG SK +++ + + + PI + + +++ ++Q +LD +GASNL+++LI+ + SN +F E +E GIALLEGGN +QKS +L S+KFF+ F + +AQ EIKS + + G+ ++++ + + RR++ + N M L++QL+DAA +++A VR + + SD++N +T+ + + ++ AEEN +L V++++PI RFLQLLCENH +LQ+ LR+Q NKT+YNLV ETL FLDCICGST+GGLGLLGLYINEHNV L++Q L TLTEYCQGPCHENQN IA HESNGIDIIIALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESR DSENAERIL N+SPKQLV+VA A++++ E + D SPKEVGHNIYIL HQL++H +ELA +L+P DS +QAL+YYA HTAQIEIVR DR+ME+IVFP+P+ICE++T E+K +V + E DEQGSKV FF T+ +F EM+WQK LR + LL+W+S HM +WS I F +++NI++ I+YPFP + ++W + SL A + + T + I+V + I+++ + + + P L +G +N++ + ++S+ GN G KS+ I ++F L H ++ +LGL HP FYSV LLD++ +EETL NVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF ME + I ++G IG +DG PE+ ER CD+L MC+ TTL QGLRNGGGIGD+LR PS KE F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+NTCFIC L+R++FDNKTV+FEEH R EHNMWHYLYFIVL+ VKDPTEFTGPESYV+ MIK +NLDWFP+ RAMSLAADE E EQN++++LQ +LE T +++S LS QL ELK+QMTEQRKQKQR LL P + Q
Sbjct: 3 SASFLHIGDIVSLYAEGNVCGFLSTLGLVDDRCVVQPDAGDLASPPKKFRDCLFRMCPMSRYSAQKQFLKAAKQSATSATDAVLLKKLHHAAELEKKQNESENKKLIGTVMQYGGVMQLLHLKSNKYLTVNKRLPALLEKNAMRVCLDSAGNEGSWFYIVPFYKLRSSGDNVVVGDKVVLTPVNAGQPLHASNYELQDNPGCKEVNAVNSNTSWKISLFMEYKENIDDVLKGGDVVRLFHAEQEKFLTMDDYKKNQYVFLRSTGRTTATAATSSKALWEVEVVQHDPCRGGAGHWNSLFRFKHLATGHYLAAEVDNDDTPDVMRNKLRGNASNNVYCLVAVPHSTDIASIFELDATTLTRGDDLVPQSSYVRLRHLCTNTWVHSTTIPIDKEEERPVMSKVGCAPIKEDKEAFAIVPVSATEVRDLDFANDACKVLDSISGSLEKGQIIQNERRFVTQLLCEVIYFVAMKENDPKKPDPLDLIVSHPNRERQKLLREQNILKQLFKILQAPFNDCGDGPILRMEELSDPRHAPFKHICRLCYRILRLSQQDYRKNQEYIAKWFGFMQKQIGYDVLAEDTITALLHSNRKLLEKHITAAEIETFVSLVRKNHES--RFLDYLSDLCISNKVAIPITQELICKAVLSPKNSDILIETRMVR---TQLEVEVEVESQNGEVEPMVTIEEEEDV---------------VLFWDNGRKSKSIRELAPGAANGN-KEDQNILSYYRHQLDLFSGMCLDRQYLAINNLSPHLDIDLIQKCMADENLPFDLRAAFCRLMLHMHVDRDPQEQITPVKYARLWSDITQKLSIQDYDANKHPDPNKEAVRAKFAPTIAFVEDYLCNVVGHMWSFADREQNKLTFEVVKLARELIYFGFYSFSDLLRLTKTLLSILDCVPESSFLNGKLTAADLDARGGVLKSIGDMGAVMTNMVLGTSGMTKQVSATMQKKASITGAEDTLVMDTKLKIIEILQFILNVRLDYRITGLLSIFKREFDESQDKSSSDDNSVNIEDKGTSGIDLERISYHAESIFGGKDDCTEIDLDGQGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVSASDVENYKQIKSDLDELRLLVEKSELWVFKSKQEETSKKKKSADDDGDGEQERKKVSKAKKKANLDLGPAGNEGSAIDLDIGPPVDPVQNKNYKTIQQILLRLTRLCVQEMPNGKKPRKHEQRLLRNMGAHAVILELLQIPYDKKEDIRMNELMRLAHEFLQHFCLDNHANQALLHKYIDLFMNPGLL-----------EAQTMRSIFMDNVSLCNELNDRVVQHFVHCIETHGRHVQYLKFLQTIVKAEGQYIRKCQDMVMQEMVNASEDVLVFYNDKTSFNHLVEMMRSERQRMDEAGPLQYHINLVKLLACCTEGKNVFTEIKCHSLLSLDDIVQVVTHPDCLPEVKEAYINFLSHCFIDTEVEMKEIYTSNH-IWTLFENFLVDMAMVCNATHDRRHADVALENYITNSVMNIITTFFNSPFSDQSTTV---QPVFVRLLQGAFRLSNCPWLSVHQRMNVESCIKTLSDIGKNRGIAIPVDLDTQVAAMFNKNAMISKHTRAWLS------AARTPRRVPSSTNVFKNDRSIIEGLQDIVSLLEDQLHPLVQSELSVLVDVLHRPELLFPPGTEARKKCENGGFISKLISHTERLLEEKEEKLCIKVLQTLKEMMSLDPDYGEKGEALRQTLLQRYFGKVQSKRDSIVNGKQALHPPKAATPITHGPGGVILTRAEMTLAEVQCHLDEEGASNLVVELIMKNPSNA-IFLESVELGIALLEGGNPVIQKSMLLKLTSGNISEKFFKVFYDKMKDAQQEIKSSVTVNTVELTNRTGDEKDTIGKDLGKDGRRIKTGLKQNGLVMTDELKEQLEDAAAATSKAYAHVRNLGTTGAAAAATE----SDLLNLGQGTHTHVALEEILAEKAEKAKDAEEN-KLPQEVVVMQPILRFLQLLCENHNYDLQNFLRNQN-NKTNYNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVSLVDQTLETLTEYCQGPCHENQNCIAVHESNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRGDSENAERILYNMSPKQLVEVACNAYHQEGED------EEDEDSEEVAEMDDGVSPKEVGHNIYILCHQLAQHNKELAAMLKPNLADPDSKMNQALQYYASHTAQIEIVRHDRTMEQIVFPVPQICEFLTRESKMQVYLKAERDEQGSKVSDFFERTDDLFNEMKWQKKLRGQPLLYWVSRHMSMWSTIAFNLAVLVNIIVAIFYPFPDFSGKIDPRLSGLMWTVMFASLAAVITVPGTTVIRIYVFSSILRMIYSVGLQPTLWILGTVNVVVTAVHLVSIMGNHGTFTKSFRQILTDFELLYHMVYLLFCILGLCAHPFFYSVLLLDVVYQEETLKNVIKSVTRNGRSIILTAVLALILVYLFSIIGYLFFRDDFLMEVDVKHIDLAGAIGVEENANNVSSEPFLSADGYCPADDTACQNRVENIYKSPEQNETVFEVQKVTPSENDDDDDDDTTPERACDSLLMCIVTTLNQGLRNGGGIGDVLRPPSAKEPLFVARVIYDLLFFFVVIIIVLNLIFGVIIDTFADLRSEKQQKEEILKNTCFICGLDRASFDNKTVSFEEHIRCEHNMWHYLYFIVLVIVKDPTEFTGPESYVASMIKDRNLDWFPRMRAMSLAADEAEGEQNEIRTLQVQLENTQKLVSTLSHQLAELKDQMTEQRKQKQRLGLLGTPPVPGSYHQ 2762
BLAST of Inositol 1,4,5-trisphosphate receptor vs. TrEMBL
Match: R7TPX0 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_222687 PE=4 SV=1) HSP 1 Score: 2778.82 bits (7202), Expect = 0.000e+0 Identity = 1529/2808 (54.45%), Postives = 1979/2808 (70.48%), Query Frame = 3
Query: 81 NIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQ-GAQT-DSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSEN--FPI-KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIP-------------------MKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQ---------QAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKK-RKDVSIQEDQVLSDLHAKYKN-----------SVTA-STIGV---ESAIELDLGPKIDQTCHKNYVTIKEILERLIVLC----ESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTI-KNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPR------------SFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMI-ILAADGNSQNSLENVMPRRRVR-----------------DRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPF-PAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLD--------------------IISGKIGSDGD------------PEKE------------------RYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWP 8087
N SFLHIGDI+SLYAEGNV+GF+STLGLVDDRCVVQP AGDL NPPKKFRDC FKICPM+R+SAQKQFW KQ G+ T +++L+ KLH AAELEK QNE E++KL+G+V+QYG+V+QLLH+KSNK LTVNKRLPALLEKNAMRVSLD+NGNEGSWF +QPFYK + GDNVVVGDKV LNPVNAGQPLH S+Y+L+D+ GCKE+N+V+CNT W+INLF++++EN DDVLKGGDVVR+FHAEQEKFLT DEYKK QYVFLRTTGRT+AT+ATSSKALWE+EVV D CRGGAG W+SLFRFKHLATGQYLAAE+D DPTPD+MRSKLR + V+CLVS+P +D+ SIFE+DPT TR D VPRSSFVR ++ CT WVHSTS+PIDKEEDKPIM KVGCA +KEDKEAFAIV VS +EVRDLDFAND SKVL+ + K++ +T N+++ V LLS +I F+ +++GSDPL++ V + DR+RQKLLREQNILKQ+FKIL++P ++N P+ KM++L+DQ+H FR ICRLCYR LKLSQQ+YRKNQEYIAKQ P MQKQIGY +LAEDTITALLHNNRKLLEKHIT SEI TF+NL+R K+ RFL +LSDLC+SN VAIP+TQELICKC+ ++N DIL++T + + VE+E E EDD + + + P I EEEEE++V WD+G +SK ++EL A + K+D+ IL YYR++L+L+SNMCLDRQYLAIN LS EL I LIL+C++++ LRASFCR+M+H+HVDRDPQE VTPV+YARLW++IP + I++Y+S ++ KE VK F +LFVE+YL N+ ++ F+++EQNKLT E+V LA+HLIYFGFY+F D LRL KTLL ILD +P K T D+ ++ GS K D ++ L+M TKL+ IEILQFILNVRLD++I+CLL IFK F++ D SK Q QAEDIF E+DLDG GG+ FLRVLLNL+MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLVS +DVENY+QIK+DLD LRLLVEKSELWVYK K KK +K+V +++ + + S++A S G+ ESAI+LD+GP +D + KNY TIKEI RL+ LC K RKHEQRLL+NMGAH+V++ELLQIP+DKK+D +M EI+ LAH FLQ FC GN SNQ +LHKN DLFLT G L EAET+ AI++DNI+LCN V E+VVQH+V CIETHG V +L+FLQTI+K++ +IRKCQD V++EL++VG+EVL+FYND + F L+ +M ++ ++ + PL YHI LV+LLA TEGKNVY+EIKCHSLL ++DI +V HP C VK AY+ FL HCYIDTEVE+K+I++ N MW LF L+D+A V ++ D+ +E+ VT T+M VI TFFNSPFS+Q+T +Q + LLQ FR TWL+ QK ++ +KT+ +I K++ I IP +L+ Q+N K Q ++KH++ W+ K+++DS ++Q + R++I+ L D + LE QL+PL+QAE+SVLV V HRPELLF +TEARHKCESGGFIS+LI HTE LL EEKLCIKVLQTL+ M+++D+E+ +K LRQ LL +Y+G++ + + +KE P V++ S +++ ++Q +LD +GAS+L++DLI+++ S+ R+F E +E GIALLEGGN+ +Q+S Y RL DK+S++FF+ F + EAQ+EIK+ + + ++ +Q S E R + + + L++QLDDAAI +++AL + + + + V E + ++ +E ++S + +++PI RFLQLLCENH R+LQ+ LR+Q+ NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINEHNV LINQ L +LTEYCQGPCHENQNAIA HESNGIDIIIALILNDINPLG+ RMDLVL LK+NASKLLLAI+ESRHDSENAERIL N+SPKQLVDVA+ A+ + +D + E E +PK+ LSKH ++LA+LL+P D D ALEYY KHTAQIEIVR DR+ME+IVFPIPEICEY+T +TK +V TE D+QGSKV FF T MF EM+WQK LRA ++LFW+ +HM LW I+F F +++NIL+ +YPF P P+ + ++W + +SL + + + + F+ A I+++ + + L+ +G LN+ N ++ +S+ GN G K+ I + EFL +I ++L L +H FYS+ LLD++ REETLLNVIRSVT+N RS++LT +L VIL Y F+I G +FF+DDF ME + LD ++SG D P+KE R+CD+L MC+ T+L +GLRNGGGIGD+LRKPS E F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+EIL+NTCFIC L+RS+FDNK+V+FEEH +H+MWHYL+FIVLIKVKDPTEFTGPESYV MIK KNL+WFP+ RAMSLAAD+ E EQN+L++LQ++LE T++++ LS QL+ELK+QMTEQRKQKQR LL + P
Sbjct: 2 NESPASFLHIGDIVSLYAEGNVNGFISTLGLVDDRCVVQPDAGDLTNPPKKFRDCLFKICPMNRYSAQKQFWKNMKQSGSHTANAVLLKKLHHAAELEKKQNESENRKLLGSVIQYGSVVQLLHLKSNKYLTVNKRLPALLEKNAMRVSLDNNGNEGSWFYIQPFYKLRSPGDNVVVGDKVVLNPVNAGQPLHASNYELVDNPGCKEVNSVNCNTCWKINLFIDHRENQDDVLKGGDVVRMFHAEQEKFLTGDEYKKKQYVFLRTTGRTSATAATSSKALWEIEVVQHDPCRGGAGHWNSLFRFKHLATGQYLAAEVDIDPTPDMMRSKLRGNPSAPVYCLVSVPHGHDIASIFELDPTTMTRGDSLVPRSSFVRFRHLCTNTWVHSTSVPIDKEEDKPIMSKVGCASIKEDKEAFAIVPVSPQEVRDLDFANDASKVLATIASKLEKSSITQNERRFVMQLLSDIICFVAVQDNTGSDPLEVTVSKPDRERQKLLREQNILKQVFKILQAPFADNGEGPVLKMEELSDQRHAPFRQICRLCYRTLKLSQQNYRKNQEYIAKQFPFMQKQIGYDVLAEDTITALLHNNRKLLEKHITASEIETFVNLVRINKEP--RFLDYLSDLCVSNRVAIPVTQELICKCVLSDSNADILIETRLVRTQVEVEMIPET------EDD-------ISENQEP--IITIEEEEEVVVFWDSGSKSKGIRELGMGAIDSIKEDQEILDYYRHELDLFSNMCLDRQYLAINRLSPELDIDLILRCMSDEMLTYELRASFCRMMLHMHVDRDPQETVTPVKYARLWSEIPTVISIEDYESNKAKDPIKEAVKHKFADTILFVEDYLCNVVCHSWSFADKEQNKLTYEVVKLARHLIYFGFYSFSDLLRLTKTLLGILD--CVPDADKSKATEDAAEGAAAAPAKTTLADV-VKKATSGSGK--------------AQDGEDGLVMETKLKIIEILQFILNVRLDYRISCLLSIFKREFDDNNDASKSAQGLDLESIGTQAEDIFGGSAESAELDLDGHGGRTFLRVLLNLVMHNYPLLVSGALQLLFRHFSQRQEVLQAFKQVQLLVSESDVENYKQIKSDLDELRLLVEKSELWVYKAKSEDGKKEKKEVRGGQEEQGQEEEERQPQHGTRHLCLLSFSLSAFSCQGLPTEESAIDLDIGPPLDASAAKNYKTIKEIFTRLMKLCVQGVGGAAAKPRKHEQRLLRNMGAHSVVLELLQIPYDKKDDTRMHEIMRLAHEFLQSFCLGNHSNQTLLHKNLDLFLTTG-----------LLEAETVRAIFQDNIQLCNEVTERVVQHFVHCIETHGRHVQYLRFLQTIVKSEGSFIRKCQDTVMAELVNVGEEVLLFYNDKVSFQTLVELMCAEGHRIDQSSPLTYHINLVQLLACCTEGKNVYTEIKCHSLLPLDDIVRVVTHPDCIPEVKNAYINFLNHCYIDTEVEMKEIYTSNH-MWTLFENFLVDMAMVCNATHDRKHADRAMEDYVTITVMNVISTFFNSPFSDQSTT--TRQPVFVRLLQGAFRTSHSTWLSGQQKFHVENCIKTLSDIAKSRSIAIPVDLDSQVNTLFNKSQLVMKHTQHWIKAGKSRRDS--------TMQINRDYRTIIEGLQDIVSLLEDQLKPLVQAELSVLVDVLHRPELLFPLNTEARHKCESGGFISKLINHTERLLEEKEEKLCIKVLQTLKEMMTVDLEYGEKGEALRQGLLTRYYGSQHPR------VAGRKEGPGPPAVQQAGGHGVNSSPGSRLLSRAEMTLHEVQCHLDREGASDLVVDLIVNNHSS-RIFLETVELGIALLEGGNSAIQRSLYNRLLSDKNSERFFKVFYDRMREAQSEIKATVSVNTSESLAQKSQEEEQDSGRKKCQCVTCPDYQLCFVLTAKSTPLSPELKEQLDDAAINTSKALTHAKAASHPDDGQVVVTDE--------------------LLAEKKEKEEKKISAEIAVMQPILRFLQLLCENHNRDLQNYLRNQS-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEHNVALINQTLESLTEYCQGPCHENQNAIASHESNGIDIIIALILNDINPLGKYRMDLVLVLKNNASKLLLAIMESRHDSENAERILYNMSPKQLVDVARQAYQQAENIDEEGEEEEEEEEDEEEK----TNPKD-----------LSKHNKDLAELLKPPP-DIPMDPALEYYEKHTAQIEIVRQDRTMEQIVFPIPEICEYLTPDTKSRVYQTTERDDQGSKVSDFFERTEDMFSEMKWQKKLRANAILFWLCSHMTLWKSISFNFAVLINILVAAFYPFSPTIIEIDPH-LSGLVWTAMFVSLAIVITLPRPLGLRTFIVAAILRLILSVGLECTLMLLGALNVCNGVLLAVSIMGNSGTFTKALRLILMDKEFLYMMGYLITSMLSLCLHEFFYSILLLDIVYREETLLNVIRSVTKNGRSILLTAMLAVILIYLFSIVGFIFFKDDFVMEVDALDAIGINKDVVAAAATSLSGAAVMSGTCTKDAKDCNVTEEQARVIPDKEAVADLVAVEEEEEEEERERFCDSLIMCIVTSLNEGLRNGGGIGDVLRKPSRTEPLFVARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEEILKNTCFICGLDRSSFDNKSVSFEEHCAFDHSMWHYLFFIVLIKVKDPTEFTGPESYVYAMIKEKNLEWFPRMRAMSLAADDGEGEQNELRNLQTQLESTNKLVQTLSSQLSELKDQMTEQRKQKQRIGLLSNPSMP 2708
BLAST of Inositol 1,4,5-trisphosphate receptor vs. TrEMBL
Match: A0A4Y2EYJ7 (Inositol 1,4,5-trisphosphate receptor type 1 OS=Araneus ventricosus OX=182803 GN=ITPR1_3 PE=4 SV=1) HSP 1 Score: 2776.5 bits (7196), Expect = 0.000e+0 Identity = 1514/2836 (53.39%), Postives = 1962/2836 (69.18%), Query Frame = 3
Query: 90 SKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGA--QTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVED--SGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFPI-KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELV-NAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD----FSAIPMKVTQLDLD---------------IESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENE--------------------IDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRK-----DVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNK----------------------QTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLET-RSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSK--NVLKINSSTKKEELSNPIVE---EIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAA------DGNSQNSLENVMPR--RRVRD-RSNIPAM---LRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEI-----AEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQP--GQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEF--LIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDI-ISGKIG---------------SDG------------------DPEK-------------------------ERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
S SFLHIGDI+SLYAEGNV GF+STLGLVDDRCVVQP AGDL +PPKKFRDC F++CPMSR+SAQKQF A KQ A TD++L+ KLH AAELEK QNE E+KKL+GTV+QYG V+QLLH+KSNK LTVNKRLPALLEKNAMRV LDS GNEGSWF + PFYK + GDNVVVGDKV L PVNAGQPLH S+Y+L D+ GCKE+NAV+ NTSW+I+LF+EYKEN+DDVLKGGDVVRLFHAEQEKFLT D+YKK+QYVFLR+TGRTTAT+ATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE+D D TPD+MR+KLR + ++V+CLV++P S D+ SIFE+D T TR DD VP+SS+VR+++ CT WVHST+IPIDKEE++P+M KVGCA +KEDKEAFAIV VSA EVRDLDFAND KVL ++ ++ I N+++ V LL VI+F+ E+ DPLDL V +R+RQKLLREQNILKQ+FKIL++P ++ + PI +M++L+D +H F++ICRLCYRIL+LSQQDYRKNQEYIAK MQKQIGY +LAEDTITALLH+NRKLLEKHIT +EI TF++L+RK +S RFL +LSDLCISN VAIPITQELICK + N DIL++T + + E + ++T+ E ++ WDNG++SK+++EL AANGN K+D++IL+YYR+QL+L+S MCLDRQYLAIN LS L I LI KC+A+++ P +LRA+FCRLM+H+HVDRDPQE +TPV+YARLW+DI +K+ I +YD+ + KE V+ F P + FVE+YL N+ + F+++EQNKLT E+V LA+ LIYFGFY+F D LRL KTLL ILD S + K+T DLD + + G+ + + + + A++TL+M+TKL+ IEILQFILNVRLD++IT LL IFK F+ ID+ +I AE IF KD+ EIDLDG+GG+ FLRVLL+L MH YP +VSGALQ+LFRHF+QRQEVLQ FKQVQLLVS +DVENY+QIK+DLD LRLLVEKSELWV+K+K K+K D ++++ K N SAI+LD+GP +D +KNY TI++IL RL LC + P K RKHEQRLL+NMGAH VI+ELLQIP+DKK DI+M E++ LAH FLQ FC N +NQ +LHK DLF+ PG L EA+TM +I+ DN+ LCN + ++VVQH+V CIETHG V +LKFLQTI+KA+ QYIRKCQDMV+ E+++ ++VLVFYND F HL+ MM S+R ++ GPLQYHI LVKLLA TEGKNV++EIKCHSLLS++DI +V HP C VKEAY+ FL HC+IDTEVE+K+I++ N +W LF L+D+A V +R D LE +T+++M +I TFFNSPFS+Q+T ++ + Q + LLQ FRL C WL+ Q+ N+ +KT+ +I K +GI IP +L+ Q+ K+ I KH++AWL+ + T PS N + RS+I+ L D + LE QL PL+Q+E+SVLV V HRPELLF P TEAR KCE+GGFIS+LI HTE LL EEKLCIKVLQTL+ M+S+D ++ +K LRQ LL +YFG SK +++ + + + PI + + +++ ++Q +LD +GASNL+++LI+ + SN +F E +E GIALLEGGN +QKS +L S+KFF+ F + +AQ EIKS + + G+ ++++ + + RR++ + N M L++QL+DAA +++A VR + + SD++N +T+ + + ++ AEEN +L V++++PI RFLQLLCENH +LQ+ LR+Q NKT+YNLV ETL FLDCICGST+GGLGLLGLYINEHNV L++Q L TLTEYCQGPCHENQN IA HESNGIDIIIALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESR DSENAERIL N+SPKQLV+VA A++++ E + D SPKEVGHNIYIL HQL++H +ELA +L+P DS +QAL+YYA HTAQIEIVR DR+ME+IVFP+P+ICE++T E+K +V + E DEQGSKV FF T+ +F EM+WQK LR + LL+W+S HM +WS I F +++NI++ I+YPFP + ++W + SL A + + T + I+V + I+++ + + + P L +G +N++ + ++S+ GN G KS+ I ++F L H ++ +LGL HP FYSV LLD++ +EETL NVI+SVT+N RS++LT +L +IL Y F+I G+LFF+DDF ME + I ++G IG +DG PE+ ER CD+L MC+ TTL QGLRNGGGIGD+LR PS KE F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+NTCFIC L+R++FDNKTV+FEEH R EHNMWHYLYFIVL+ VKDPTEFTGPESYV+ MIK +NLDWFP+ RAMSLAADE E EQN++++LQ +LE T +++S LS QL ELK+QMTEQRKQKQR LL P + Q
Sbjct: 3 SASFLHIGDIVSLYAEGNVCGFLSTLGLVDDRCVVQPDAGDLASPPKKFRDCLFRMCPMSRYSAQKQFLKAAKQSATSATDAVLLKKLHHAAELEKKQNESENKKLIGTVMQYGGVMQLLHLKSNKYLTVNKRLPALLEKNAMRVCLDSAGNEGSWFYIVPFYKLRSSGDNVVVGDKVVLTPVNAGQPLHASNYELQDNPGCKEVNAVNSNTSWKISLFMEYKENIDDVLKGGDVVRLFHAEQEKFLTMDDYKKNQYVFLRSTGRTTATAATSSKALWEVEVVQHDPCRGGAGHWNSLFRFKHLATGHYLAAEVDNDDTPDVMRNKLRGNASNNVYCLVAVPHSTDIASIFELDATTLTRGDDLVPQSSYVRLRHLCTNTWVHSTTIPIDKEEERPVMSKVGCAPIKEDKEAFAIVPVSATEVRDLDFANDACKVLDSISGSLEKGQIIQNERRFVTQLLCEVIYFVAMKENDPKKPDPLDLIVSHPNRERQKLLREQNILKQLFKILQAPFNDCGDGPILRMEELSDPRHAPFKHICRLCYRILRLSQQDYRKNQEYIAKWFGFMQKQIGYDVLAEDTITALLHSNRKLLEKHITAAEIETFVSLVRKNHES--RFLDYLSDLCISNKVAIPITQELICKAVLSPKNSDILIETRMVR---TQLEVEVEVESQNGEVEPMVTIEEEEDV---------------VLFWDNGRKSKSIRELAPGAANGN-KEDQNILSYYRHQLDLFSGMCLDRQYLAINNLSPHLDIDLIQKCMADENLPFDLRAAFCRLMLHMHVDRDPQEQITPVKYARLWSDITQKLSIQDYDANKHPDPNKEAVRAKFAPTIAFVEDYLCNVVGHMWSFADREQNKLTFEVVKLARELIYFGFYSFSDLLRLTKTLLSILDCVPESSFLNGKLTAADLDARGGVLKSIGDMGAVMTNMVLGTSGMTKQVSATMQKKASITGAEDTLVMDTKLKIIEILQFILNVRLDYRITGLLSIFKREFDESQDKSSSDDNSVNIEDKGTSGIDLERISYHAESIFGGKDDCTEIDLDGQGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVSASDVENYKQIKSDLDELRLLVEKSELWVFKSKQEETSKKKKSADDDGDGEQERKKVSKAKKKANLDLGPAGNEGSAIDLDIGPPVDPVQNKNYKTIQQILLRLTRLCVQEMPNGKKPRKHEQRLLRNMGAHAVILELLQIPYDKKEDIRMNELMRLAHEFLQHFCLDNHANQALLHKYIDLFMNPGLL-----------EAQTMRSIFMDNVSLCNELNDRVVQHFVHCIETHGRHVQYLKFLQTIVKAEGQYIRKCQDMVMQEMVNASEDVLVFYNDKTSFNHLVEMMRSERQRMDEAGPLQYHINLVKLLACCTEGKNVFTEIKCHSLLSLDDIVQVVTHPDCLPEVKEAYINFLSHCFIDTEVEMKEIYTSNH-IWTLFENFLVDMAMVCNATHDRRHADVALENYITNSVMNIITTFFNSPFSDQSTTVQKQLLHARVFWAQGQLTAIDLSDTHQPVFVRLLQGAFRLSNCPWLSVHQRMNVESCIKTLSDIGKNRGIAIPVDLDTQVAAMFNKNAMISKHTRAWLS------AARTPRRVPSSTNVFKNDRSIIEGLQDIVSLLEDQLHPLVQSELSVLVDVLHRPELLFPPGTEARKKCENGGFISKLISHTERLLEEKEEKLCIKVLQTLKEMMSLDPDYGEKGEALRQTLLQRYFGKVQSKRDSIVNGKQALHPPKAATPITHGPGGVILTRAEMTLAEVQCHLDEEGASNLVVELIMKNPSNA-IFLESVELGIALLEGGNPVIQKSMLLKLTSGNISEKFFKVFYDKMKDAQQEIKSSVTVNTVELTNRTGDEKDTIGKDLGKDGRRIKSLKQNGLVMTDELKEQLEDAAAATSKAYAHVRNLGTTGAAAAATE----SDLLNLGQGTHTHVALEEILAEKAEKAKDAEEN-KLPQEVVVMQPILRFLQLLCENHNYDLQNFLRNQN-NKTNYNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVSLVDQTLETLTEYCQGPCHENQNCIAVHESNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRGDSENAERILYNMSPKQLVEVACNAYHQEGED------EEDEDSEEVAEMDDGVSPKEVGHNIYILCHQLAQHNKELAAMLKPNLADPDSKMNQALQYYASHTAQIEIVRHDRTMEQIVFPVPQICEFLTRESKMQVYLKAERDEQGSKVSDFFERTDDLFNEMKWQKKLRGQPLLYWVSRHMSMWSTIAFNLAVLVNIIVAIFYPFPDFSGKIDPRLSGLMWTVMFASLAAVITVPGTTVIRIYVFSSILRMIYSVGLQPTLWILGTVNVVVTAVHLVSIMGNHGTFTKSFRQILTDFELLYHMVYLLFCILGLCAHPFFYSVLLLDVVYQEETLKNVIKSVTRNGRSIILTAVLALILVYLFSIIGYLFFRDDFLMEVDVKHIDLAGAIGVEENANNVSSEPFLSADGYCPADDTACQNRVENIYKSPEQNETVFEVQKVTPSENDDDDDDDTTPERACDSLLMCIVTTLNQGLRNGGGIGDVLRPPSAKEPLFVARVIYDLLFFFVVIIIVLNLIFGVIIDTFADLRSEKQQKEEILKNTCFICGLDRASFDNKTVSFEEHIRCEHNMWHYLYFIVLVIVKDPTEFTGPESYVASMIKDRNLDWFPRMRAMSLAADEAEGEQNEIRTLQVQLENTQKLVSTLSHQLAELKDQMTEQRKQKQRLGLLGTPPVPGSYHQ 2786
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Cavefish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3]) HSP 1 Score: 2595.85 bits (6727), Expect = 0.000e+0 Identity = 1408/2742 (51.35%), Postives = 1882/2742 (68.64%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQG--AQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSK-----------LRKSGDDD--VFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGK---QSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQ-----------------KPGSF---KEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE----------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESD---DPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD--GNSQ---NSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVI-WLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPE----------FLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ SGF+STLGLVDDRCVVQP AGDL+NPPKKFRDC F++CPM+R+SAQKQFW A K G + TD++L+NKLH AA+LEK QNE E+KKL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LD+ GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH S + L+D+ GC E+N+V+C+TSW+I LF+++ +N + VLKGGDVVRLFHAEQEKFLTCD+++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE++ D + + S+ L K D ++ LVS+P ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDKEE+KP+M ++G + LKEDKEAFAIV VS EVRDLDFAND SKVL+ + K++ TI N+++ V LL +++F+ + +S D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELIC + N DIL++T+ D + N T E+EEE+ + W + +SK+++EL A +D+ +++YYRYQLNL++ MCLDRQYLAIN +S++L + LIL+C++++ P +LRASFCR+M+H+HVDRDPQE VTPV+YARLW++IP ++ ID+YD+ + ++EVK F M FVE YL ++ + FS++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + V + + S + G F + + + L+M+TKL+ IEILQFILNVRLD++I+CLL IFK F+ + +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VS AL +LFRHF+QRQEVLQ FKQVQLLV++ DVENY+QIKADLD LR +VEKSELWVYK + S + + S+ H K +S++ G++ PK++ T NY +KEIL RL LC + K++K +QRLL+NMGAH+V++ELLQIP++K D+ MQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L+ MM +R +L N L+YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF+ L+DI +V ++ D LE VT TIM ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ +K + ++ K + I IP +L+ Q+N +K I+ K + +W L+ +N ++DS T + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF HTEA KCESGGFI +LIKHT+ LL NEE+LCIKVLQTLR M++ D + +K LRQ L+ +Y+GN S + S ++S ++Q +LD +GAS+L+IDLI++ +S +RVF E I IALLEGGNT +Q+SF++RL DK S+KFF+ F + AQ EIK+ + + GN + + + P+RR + R QL +A+ + +A + R+ + +E + + EE +S ++I+EPI RFLQLLCENH R+LQ+ LR Q NK +YNLVCETLQFLDCICGST+GGLGLLGLYIN+HNV LINQ + +LTEYCQGPCH+NQN IA HESNGIDIIIALILNDINPLGR RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A Y+ D D+ E +GE ASP+ VGHNIYILAHQLS+H +EL LL+P S DQA+E Y KHTAQIEIVR DR+ME+IVFP+P IC ++T E+K +V TE DEQGSK+ FF + ++ EM+WQK LRA+ +L+W S +M WS+++F +++N+L+ +YP + ++ +S++ W+ ++ SL V + + +V I V + ++++ F L + L +G N+ N I+F++S GNRG + + + + EFL H ++ LGL H FYS+ L DL+ REETLLNVI+SVT+N RS+VLT +LG+IL Y F+I G++FF+DDF +E ++ + +D + ER CD+L MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ K+E+L+ TCFIC L R FDNKTVTFEEH + EHN+WHYLYFIVL++VKD TE+TGPESYV++MIK NLDWFP+ RAMSL + + E EQN+L+ LQ +LE T +++SNL++QLTELK QMTEQRK KQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWKAAKPGGTSTTDTVLLNKLHHAADLEKKQNESENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASGHQLVDNPGCNEVNSVNCSTSWKIVLFMKWSDNQEVVLKGGDVVRLFHAEQEKFLTCDDHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSVSVCLLYTQLWKKLRDHFIMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNHPIDKEEEKPVMLRIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRAVTKLLEDLVYFVVDIPNSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICNAVLDPANGDILIETKY---------------------DKICATNHCRLTDR-------EDEEEVWLFWKDSSGEVKSKSIRELAQDAKDGHTEDQEVISYYRYQLNLFARMCLDRQYLAINKISAQLDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDN---DGTSRDEVKEKFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVSYLVFLVSVCAGSNVMRSIHGVGELMTQVVLRGGGFLPPTSRVAPDRDSVKAQAEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLSIFKREFDESNSQVEPSINPDSHTSALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKADLDQLRSIVEKSELWVYKRQGSDSGLHTG-----EGIASETHHK-SDSISD---GMDK-------PKVESTSSSNYRLMKEILLRLSKLCVMECLSGRKNKKQQQRLLRNMGAHSVVLELLQIPYEK--DVWMQEIMTLAHQFLQNFCAGNQQNQTLLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRSVHYLKFLQTIVKAENKFIKKCQDIVMAELVNAGEDVLVFYNDRASFQTLVQMMRLERERLDDNSALRYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYVDTEVEMKEIYTSNH-MWKLFDDFLVDICRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPFSDQSTSLQTRQPVFVQLLQGVFRVYHCNWLLPSQKGSVEGCIKVLSDVAKGRAIAIPVDLDCQVNNLFIKSNNIVQKTALSWRLSARNATRRDSVLTASR--------DYRNIIERLQDIVSALEERLRPLVQAELSVLVDVLHRPELLFPEHTEAHRKCESGGFICKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKGEALRQLLVNRYYGNFRSGAL----------------------SRAEMSLTEVQCHLDREGASDLVIDLIMNTNS-DRVFHESILLAIALLEGGNTTIQRSFFKRLTEDKKSEKFFRVFYDRMKAAQLEIKATVTVNTSDLGNKRRDDHGSDRDTPQRRRDSVVMVTDDARDQLLEASAVTKKAYGSYRRDAD--------------------PEEAYGHTDGDRGGGDKGEEQGEMSPVILIMEPILRFLQLLCENHNRDLQNFLRCQN-NKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINQHNVALINQTIESLTEYCQGPCHDNQNCIATHESNGIDIIIALILNDINPLGRKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKA-YQQGEADFDE--EEENGE------DHAASPRNVGHNIYILAHQLSRHNKELQLLLKP----SGEDQAVECYTKHTAQIEIVRQDRTMEQIVFPVPHICSFLTSESKLRVYYSTERDEQGSKINDFFLRADDLYNEMRWQKKLRAQPVLYWCSRNMSFWSNVSFNLAVLINVLVAFFYPLDSVRDSTLEPSLSLLLWVCVLGSLGFVVLLPSPNAVRILVISSVLRLGFSLGLQHMLSLLGAFNVCNKIVFLLSFVGNRGTFTRGYRAMVMDREFLFHLLYLLICTLGLCGHVFFYSLLLFDLVNREETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYIFFKDDFILEVNRIPNRNINVCVFGMLCPFVCAD---DVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFLVIIIVLNLIFGVIIDTFADLRSEKQRKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLYFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRCLQEKLESTMRLVSNLTNQLTELKEQMTEQRKHKQRIGLL 2617
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Cavefish
Match: itpr1b (inositol 1,4,5-trisphosphate receptor, type 1b [Source:ZFIN;Acc:ZDB-GENE-070604-2]) HSP 1 Score: 2593.15 bits (6720), Expect = 0.000e+0 Identity = 1406/2803 (50.16%), Postives = 1885/2803 (67.25%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD-------------PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW----DNGKQ--SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPM--KVTQLDLDIESQ--------------------KPGSF---KEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQ-----FILNVRLDFQ-ITCLLCIFKAHFE-----------------------NEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLC---ESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPS-LQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGN-----------KLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLENVMPRRRVRDRSNIPAM-----LRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVS-VIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDF----------QMEPEFLDIISGKIGSDGDPE-----------------KERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL-RPENWPATNQQ*A 8108
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP GDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K G TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LDS GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH S++ L+D+ GC E+N+V+CNTSW+I LF+++ +N + +LKGGDVVRLFHAEQEKFLTCD+++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE++ D + +R++LR + ++ LVS+P ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDKEE+KP+M ++G + +KEDKEAFAIV V EVRDLDFAND SKVL+ + K++ TI N+++ V LL ++FF+ + +SG D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF++L+RK ++ RFL +LSDLC+S N +IP+TQELIC + N DIL++T+ L ++ E E EE+ W D+ K+ SK+++EL A K+D+ +++YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP K+ ID+YD+ + ++E+K F M FVE YL ++ N+ FS++E+NKLT E+VNLA++LIYFGFY+F D LRL K LL ILD + + +++ D E++ + G F ++ + + ++ L+M+TKL+ IEILQ + L L + I+CLLCIFK F+ +D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGAL +LFRHF+QRQEVL FKQVQLLV++ DV+NY+QIK+DLD LR +VEKSELWVYK + D + D +H+K K + T NY +KEIL RL LC + KS+K +QRLL+NMGAH+V++ELLQIP++K D++MQEI+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V CIETHG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L+ MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI +V ++ D LE VT T+M ++ TFF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ +K + ++ K++ I IP +L+ Q+N +K +++ TI N + S R S L + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +T+AR KCESGGFIS+LIKHT+ LL NEE+LCIKVLQTLR M++ D + +K LRQ L+ +Y+GN S L +K + S ++S ++Q +LD +GAS+L+IDLI++ +S +R+F+E I IALLEGGNT +Q+SF+ RL D S+KFF+ F + AQ EIK+ + + +D S+ E+ + + +R+QL +A+ + +A A R+ ++ D+ + + ++I +EN +S ++ I++PI R +QLLCENH RELQ+ LR Q NK +YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ + +LTEYCQGPCHENQN IA HE NGIDIIIALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + ++ E + E G ASP+ VGHNIYILAHQL++H +EL +L+ + D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K +V TE DEQGSK+ FF + +F EM WQK LRA+ +L+W S +M WS I+F ++MN+L+ +YP + +S ++W+ +++SL + + + + + I+++ F + + P L +G N+ N +IF++S GNRG + + + + EFL H +I LG+ VH FYS+ L DLI REETLLNVI+SVT+N RS+VLT +L +IL Y F+I G++FF+DDF M EFL G +G E KER CD+L MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTVTFEEH + EHNMWHYL+FIVLIKVKD TE+TGPESYV+EMI+ NLDWFP+ RAMSL + + E EQN+++SLQ +LE T +++SNLS QLTELK QMTEQRKQKQR LL P++ QQ A
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPDTGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASTHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKEVILKGGDVVRLFHAEQEKFLTCDDHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEESHESRSSLDSEHEALRARLRTPNEKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNNPIDKEEEKPVMLRIGTSAIKEDKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKLLEDLVFFVVDIPNSGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETK-------------------------LVLSRFEIEAVNVGEPPVEAEEDEEEVWLFWKDSTKEIRSKSIRELAQDAKEGQKEDQEVVSYYRYQLNLFARMCLDRQYLAINKISGQLDVDLILRCMSDEDLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSKIAIDDYDN---DGTTRDEIKERFALTMDFVENYLRDVVCQNVPFSDKEKNKLTFEVVNLARNLIYFGFYSFSDLLRLTKILLAILDCVHVSTIYPINKMEKDDENKGSNVMRSIHGVGELMTQVVLRGGGFLPTTPTAPPDGEVGKTQTEPEKEDILVMDTKLKIIEILQVTGKLWTLGTVLSYGLISCLLCIFKREFDETNTQTDSLINSNANANSEWSIAKSLDFENIEEQAEGIFGASEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSIVEKSELWVYKRQGDDALDGGDGPAESDHK-KKVHSK----------------------KPESTSSYNYRVVKEILVRLSRLCVQEGASGKKSKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVRMQEIMKLAHEFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAITMQHIFMNNFQLCSEINERVVQHFVHCIETHGRHVQYLKFLQTIVKAENKFIKKCQDIVMAELVNAGEDVLVFYNDRASFQTLVQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYIDFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRVCNNTSDRKHADATLERYVTETVMSIVTTFFSSPFSDQSTSLQTRQPVFVQLLQGVFRVYHCNWLVPTQKASVESCIKVLSDVAKSRAIAIPVDLDSQVNNLFVKSNNVVQK-----TILNWRMSARNASRRDSTLTTSKDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARTKCESGGFISKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKGEALRQILVNRYYGNFKPGGRRDSLTSFSNGPLGAGGQSKAPAAAAGGSGG---SRGEMSLAEVQCHLDREGASDLVIDLIMNATS-DRIFQESILLAIALLEGGNTVIQRSFFIRLTRDNKSEKFFKVFYERMKLAQQEIKATVTVNTSDLGSKRKDEDTNDKEAPTKKKVKDVAVVTDEVREQLLEASTVTKKAFAAYRREVDS-------------------DEHLSGGEVQTSTAEKIQDEN-EMSVTITIMQPILRLMQLLCENHNRELQNFLRCQN-NKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTVESLTEYCQGPCHENQNCIATHECNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQG------EIEVEHTDEEGEGEEEHAASPRNVGHNIYILAHQLARHNKELQAMLKAAGSYGEGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPNICEFLTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPILYWCSRNMSFWSSISFNLAVLMNLLVAFFYPLGGIRGGTLDPHLSALLWVAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTLFLLGAFNVCNKVIFLMSFVGNRGTFTRGYKAMIMDVEFLYHLLYLIICSLGVFVHVFFYSLLLFDLIYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIFFKDDFILAVDRIPNKTMMSEFL--TGGVCRKEGGGENCSSEVTTETVAMVVEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLIKVKDSTEYTGPESYVAEMIREHNLDWFPRMRAMSLVSSDAEGEQNEIRSLQEKLESTMKLVSNLSGQLTELKEQMTEQRKQKQRIGLLGHPQHMNVNPQQPA 2706
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Cavefish
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192]) HSP 1 Score: 2400.55 bits (6220), Expect = 0.000e+0 Identity = 1352/2730 (49.52%), Postives = 1790/2730 (65.57%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNAT--KQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLS--ENFPI-KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMK-------------------------VTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHF---------------------ENEIDISKICQQAEDIFS----EKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWV-----YKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQA--ILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGN-KLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFP--AKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSE--FLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPE---FLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI+SLYAEG V+GF+STLGLVDDRCVVQP AGDL NPPKKFRDC FK+CPM+R+SAQKQFW A KQG T+ L KL AAELE+ QNE E+KKL+G VV+Y VIQLLHIKSNK LTVNKRLPALLEKNAMRVSLD +GNEGSWF +QPF+K + GDNVVVGDKV L PVNAGQPLH S+ +LLD+ GC E+NAV+CNTSW++ LF+++ + DD+LKGGDVVRLFHAEQEKFLTCD+YK Q++FLRTT R +ATSATSSKALWEVEVV+ D CRGGAG+W+SLFRFKHLATG+YLAAE + D + SK ++ + + LVS+P ND+ S+FE+D T R+D VPR+S+VR++N CT WV ST+ ID EE++P+M K+G KEDKEAFAIV V EVRDLDFAND +KVL +K++ T ND++ V LL ++FF+C V ++G D L + + +R+RQKL+REQNIL QIF IL++P + E+ PI K++DL DQ++ F+ + +LCYRIL+ SQQDYRKNQEYIAK+ +MQ QIGY ILAEDTITALLHNNRKLLEKHIT EI TF+ L+R+ ++ RFL +LSDLC+SN AIP+TQELICK + + N DIL++T++ + D++ + + ++ K P K+++ L + GN K D I+TYYR QLNL++ MCLDRQYLAIN +S++L + LIL+C+ +D P NLRASFCRLM+H+HVDRDPQE V PVRYARLW +IP K+ + +E+ + ++K F P M FV+EYL ++ + F ++E+N+LTLE+VNLA++L+YFGFY+F + L L +TLL ILD P+ +TQ+ L S P S + S ++ + D + ++M+TKLR IEILQFIL+VRLD++IT LL I+K F E+ ++ +I ++AE +F+ E+D V LD EGG+ FLRVL++LIM YP +VSG+LQ++F+HF+QR EVLQ FKQVQLLVS DVENY+QIKADLD LRL VEKSELWV Y N+ ++ + KD I E + L H Y N NY+ +KEIL+RL LC S KSR +QRLLKNMGAH V+++LLQIP++ K D KM EI+ LAH FLQ FCN N NQ +LHK+ +LFLTPG L EA TM I+++N LCN + ++VV H+V CIETHG + +L+FLQTI+K+ +Y++KCQD V++EL++ G+EVL+FYND F L+ +M S+R + N L YHI LV+LLA TEGKNVY+EIKC+SLL ++DI N+V H C VK AY+ F+ HCY+DTEVE+K+I++ N +W LF + +D+ +V + ++ D +E+ VT TIM ++ FF S FS N+ ++ Q I LLQ FR+Y C+W+++ QK+NI +KT+ ++ K +L P +L+ Q+N LK + + +K W Q + R + +++I+ L + L+ Q P +QAE SVLV V H PELLF P AR +CESG F+++LIKHT+ L+ EEKLCIK+LQTLR M+ FDD+ N LR+ +L YFGN +L L SS + E V V+IQ LDS GAS L+IDLI+ + N+RVF E I+ GIALL GGN+ Q SF+ +L K S+KFF+ F + AQ EI+S + S N E I+ RK +++ E V+G+ + +++S++ ++S ++ I+EPI RFLQLLCENH R LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV L+ Q L T+TEYCQGPCHENQ+ IA+HESNGIDIIIALI+N I PLG+ RMDLVL+LK+NASKLLLAI+ES HDSENAE+IL + P +LV ++ A P E T H+++ L++H+++L Q L+P DS T+ +L YYAKHTAQIEIVR DRSME+IVFP+P ICEY+TEE+K +V T TE D+QGSKV FF + + ++ EM WQK +R+ L H+ LW I+F +++N+ + ++YPF E P ++ ++W+ +V+S + +L F+ +I++ + + + P L+ +G NL+N I+F++S GN+G + + + + FL+H +I +LGL VH FYS+ L DL+RREETLLNV+RSVT+N RS+ LT +L +IL Y F+I G LF Q DF ME + LD ++ K+ +PE ER C+TL MC+ T L GLRNGGGI DILRKPS E F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ K+EIL+ TCFIC L R FDNKTV+FEEH + EHNMWHYLYF+VL++VKDPTE+TGPESYV++MIK KNLDWFP+ +AMSL E EQN+++SLQ +L+ T ++S LS QL ELK QMTEQRK KQR L
Sbjct: 7 SFLHIGDIVSLYAEGTVNGFISTLGLVDDRCVVQPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQFWKAKQGKQGGNTEGDLFKKLQHAAELEQKQNETENKKLLGEVVKYSQVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDPSGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNAGQPLHASNIELLDNPGCNEVNAVNCNTSWKVTLFMKFSDYKDDILKGGDVVRLFHAEQEKFLTCDDYKDQQHIFLRTTLRQSATSATSSKALWEVEVVHYDPCRGGAGQWNSLFRFKHLATGKYLAAETESDA----VYSKKKRPVEKITYILVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRNLCTNTWVTSTNNSIDHEEERPVMLKIGTCPTKEDKEAFAIVSVPLSEVRDLDFANDANKVLEAFVRKLEKNTFAQNDRRFVIKLLEDLVFFVCEVPNNGQDVLSVVISNPNRERQKLMREQNILAQIFGILKAPFADREDGPILKLEDLGDQRYAPFKYMLQLCYRILRHSQQDYRKNQEYIAKKFSIMQSQIGYEILAEDTITALLHNNRKLLEKHITAREIETFVKLLRRNREP--RFLDYLSDLCVSNKTAIPVTQELICKFMLNPTNADILIQTKLIPHTENSMDSSLMHEEG---DEEEVWLYWIDHNKEP--------------------HGKSIRHLAQDSKGNHKLDIDIITYYRCQLNLFAKMCLDRQYLAINQISTQLPVDLILRCMFDDCLPYNLRASFCRLMLHMHVDRDPQEAVVPVRYARLWNEIPSKISV-------KEDTSRADMKRKFAPTMDFVDEYLKDVLSQPFPFGDEEKNELTLEVVNLARNLVYFGFYSFSELLCLTRTLLAILDIVQHPLTFMSKLSKGPDGGNNVLRTIHGVGEMMTQMVLSRGSMLPHSLPD-SQPMMGHGKPLCVLDNQDVMVMDTKLRIIEILQFILSVRLDYRITYLLSIYKKEFGEQNVTDNTLSVSDFPPAQSGESLPNVEEIAEKAEIMFTGSGVERDLVA---LDDEGGRTFLRVLIHLIMQDYPPLVSGSLQLIFKHFSQRAEVLQAFKQVQLLVSEKDVENYKQIKADLDQLRLTVEKSELWVEKSGSYGNEDMTENQNKD-QIMEVRPLLACHFIYSN---------------------------NYIIVKEILQRLSKLCYSVK-KSRVQQQRLLKNMGAHVVVLDLLQIPYE-KGDEKMLEIMTLAHTFLQNFCNDNPQNQILLHKHLNLFLTPGIL-----------EARTMHYIFQNNYHLCNEISDRVVHHFVHCIETHGRSIHYLRFLQTIVKSDGKYVKKCQDKVMTELVNGGEEVLLFYNDRASFPALLQLMNSERERHDENSALSYHINLVELLAACTEGKNVYTEIKCNSLLPLDDIVNVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNH-IWKLFESFRVDMDRVCNSTTDRKHADTMMEKYVTETIMAIVKGFFASQFSVNNSNLQTHQPIFIQLLQAAFRVYNCSWVSSLQKSNIEACIKTLSDVGKTVTLLSPVDLDSQVNTFSLKSHTNMVQRAAKDW--------RQSARRPRKEPLGAPDYKNIIEKLQGVVSFLKEQFSPRVQAEFSVLVDVLHSPELLF-PEA-ARMRCESGAFMTKLIKHTKKLM-EKEEKLCIKILQTLREMLDKKETFDDRGNALRKTMLTHYFGNQRLHSKALDYGSSGQDSEKPGTTV------------VEIQCLLDSVGASELVIDLIV-STKNDRVFEESIQLGIALLRGGNSQTQNSFHHQLHKQKKSEKFFKVFYDRMQLAQKEIRSTV-------SVNMFE---------------------------------ISCRKR--------EEEGE-----VSGVRHKKGGAHLSHL--------EVQMSQAITIMEPILRFLQLLCENHNRHLQNFLRDQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINERNVDLVIQTLETITEYCQGPCHENQSCIAKHESNGIDIIIALIVNPIEPLGKNRMDLVLKLKNNASKLLLAIMESCHDSENAEQILDKMRPNELVSESRPA-----------APGAVHLENTCT------------HSLF-----LARHRKQLQQSLKPCP-DSDTEDSLGYYAKHTAQIEIVRHDRSMEQIVFPVPNICEYLTEESKVRVFTTTERDDQGSKVNHFFQQFDDLYNEMWWQKKMRSMFLF-----HISLWGSISFNLAVLVNMAVALFYPFGDDDDEGVLPPLLSVLLWVAVVVSTSLLFILPRQGGILAFLVTIILRSIYTIGLHPTLVLLGAANLLNKIVFLVSFVGNQGTFTRGYKAVIMDIFFLLHVFYVIVCMLGLFVHEFFYSILLFDLVRREETLLNVMRSVTKNGRSIFLTAVLAIILVYLFSIVGFLFLQSDFLMEVDRHPALD-LTCKVEKSDEPEMERVCETLLMCIVTVLNHGLRNGGGIADILRKPSKDEPMFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVSFEEHIKVEHNMWHYLYFLVLVRVKDPTEYTGPESYVAQMIKEKNLDWFPRMQAMSLVTSAGESEQNEMRSLQEKLDITVTLVSQLSAQLAELKEQMTEQRKNKQRMGFL 2533
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Cavefish
Match: ryr1b (ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:ZDB-GENE-070705-417]) HSP 1 Score: 152.525 bits (384), Expect = 5.890e-36 Identity = 84/241 (34.85%), Postives = 133/241 (55.19%), Query Frame = 3
Query: 7173 VLGLLVH--PLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFP 7889
V+ LL H F++ LLD+ +TL ++ SVT N + L++T L ++ Y +T+ FF+ + M S+ + E + CD + C +Y G+R GGGIGD + P+ E + +RV+ D++F+F V VI+L +I G+IID F LR +++ E + CFIC + FD FE H EHN+ +Y++F++ + KD TE TG ESYV +M + + D+FP
Sbjct: 4717 VMSLLGHYNNFFFACHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNM-------------SEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDE-YELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4943 HSP 2 Score: 82.8037 bits (203), Expect = 6.700e-15 Identity = 129/591 (21.83%), Postives = 249/591 (42.13%), Query Frame = 3
Query: 345 LHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSL--DSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVS--SYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCD--EYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPT---PDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHL-------------TINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHV-IFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQI-----GYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEI 2033
L + +L ++ H+ L+ YG I L H S+ L+ +L +K A+ V L DS G E W+ + P K + G+ V VGD + L V++ + LH+S S DL+ ++A T W +N E + L GG V+RLFH ++ L + +DQ + + +++LW +E + + + GG KW FR +H++TG+Y+ + +K P+ +KL FC + + +V +++ + Y FV ++ TG W+ ++ + +V +L ++ + +S + + A + + Q IK L T+ V+ +L + +F E+ + +++ + R+RQ L +E+ ++ + + ++ N + ++ ++ I L Y +L + R N L + ++ GIL + + +L + ++L I + I + I+L+ K + + L L LC+ N VA+ Q LI + L +D+L++T I
Sbjct: 65 LANTVDLSESSQGGAHRTLL-----YGHAILLRHNHSSMYLSCLTTSRSLTDKLAIDVGLQEDSTG-EACWWTIHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSMASGDLM-------VDASFMQTLWNMNPVCSGCELAEGFLTGGHVLRLFHGHMDECLAISPPDQGEDQIA-----QYESGAVCSQARSLWRLEPL-RISWSGGHMKWGQAFRIRHISTGRYVCLDEEKGLMVLDPEKANTKL------SAFCFRASKEKVEVAKKRDVE-GMGIPEIKYGESMCFV--QHVSTGLWLTYAALDAKAARLGTMKRRV---ILHQEGHMDDALLLSRSQTEESQAARMIYSTTGLFNQFIKGLDSLSGKNRAPGPVTLPLDAVILSLQDLIHYFRPPEEELEHEEKQTKLRSL-RNRQNLFQEEGMITIVLECVDRLNVYNTAAHFSEFAGEEAAESWKEIVNLLYELLASLIRGNRSNCALFCDNLDWLVSKLDRLEASSGIL--EVLYCVLIESPEVLNI-IQENHIKSIISLLDK-HGRNHKVLDVLRSLCVCNGVAVRSNQNLITENLL--PGRDLLLQTSI 617
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Cavefish
Match: ryr3 (ryanodine receptor 3 [Source:ZFIN;Acc:ZDB-GENE-041001-165]) HSP 1 Score: 149.058 bits (375), Expect = 6.267e-35 Identity = 80/231 (34.63%), Postives = 127/231 (54.98%), Query Frame = 3
Query: 7197 LFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFP 7889
F++ LLD+ +TL ++ SVT N + LVLT L ++ Y +T+ FF+ + S+ + + CD + C +Y G+R GGGIGD + P+ + + +R+L D++F+F V VI+L +I G+IID F LR +++ E + CFIC + FD FE H +EHN+ +YL+F++ + KD TE TG ESYV +M + + D+FP
Sbjct: 4473 FFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNK-------------SEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPA-GDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4689 HSP 2 Score: 61.6178 bits (148), Expect = 1.744e-8 Identity = 43/166 (25.90%), Postives = 73/166 (43.98%), Query Frame = 3
Query: 540 EGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLT--CDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDK 1031
E W+ + P K + G+ V +GD + L V++ + LH+S + G +++A T W + L GG V+RLFH E D+ + Q V + +++LW +E + + + G +W FR +HL+TG YL D+
Sbjct: 111 EACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERFLHLSMSN-----GNIQVDASFMQTLWNVQPTCSGSNVAVGYLLGGHVIRLFHGHDESLTVPGSDQSGEQQRV----ANYEAGKGGSRARSLWRLEPL-RISWSGSHIRWGQPFRLRHLSTGHYLGQTEDR 266 HSP 3 Score: 56.9954 bits (136), Expect = 3.810e-7 Identity = 35/99 (35.35%), Postives = 50/99 (50.51%), Query Frame = 3
Query: 5844 IFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTS--XXXXXXXXYINEHN-------VGLINQNLRTLTEYCQGPCHENQNAIAQ 6113
+FRFLQLLCE H + Q+ LR Q N T+ N++ T+ +L + S S I+E + + Q +LTEY QGPC NQ ++A
Sbjct: 3585 LFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDIIDEQGQRNFSKALAVAKQIFNSLTEYIQGPCIGNQQSLAH 3683
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007816.1 (pep scaffold:Pmarinus_7.0:GL476823:160879:205429:-1 gene:ENSPMAG00000007060.1 transcript:ENSPMAT00000007816.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 690.263 bits (1780), Expect = 0.000e+0 Identity = 433/952 (45.48%), Postives = 560/952 (58.82%), Query Frame = 3
Query: 5415 QKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAH------------------------------QLSKHKRELAQLLQ-PGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNH--PNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFL------------DIISGKIGSDGDPEKERYCDTLGM-CLTTTLYQGLRNGGGIGDILR------------------------------KPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICA--LNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQM 8030
Q SFY RL DK S+KFF+ F + AQ EIK+ + + S E DD A + L +V S G + + E+ +S + I+EPI RFLQLLCENH LQ+ LR Q NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NVGLINQ L +LTEYCQGPCHENQN IA HESNGIDIIIALILNDINPLG+ RM+LVLELKDNASKLLLAI+ESRHDSENAERIL N+ PK+LV V K A++++ D V E S SPKEVGHNIYILAH QL++H +EL Q+L +AL+YY KHT+QIEIVR DR ME IVFP+P +CE++T ++K +V TE D+QGSK+ FF ++ +F EM WQK LR ++LLF V+W I+ T+ MN+L+ +YPF + P + ++WL +++ L V + SV V +I+++ F + P L+ +G N++N ++F++S GN+G + ++ EFL H S +I LGL++H FYS+ L DL+ REETLLNVI+SVT+N RS+VLT +L +IL Y F+I G LF +DDF ME + L IS + + G + M CL L L+ + R +P +E F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFICA L R FDNKTV+FEEH + EHNMW+YLYFIVLIKVKDPTE+TGPESYV++MI+ +N+DWFP+ RAMSL + E E EQN+++ LQ +LE T ++IS L QL+ELK Q+
Sbjct: 1 QHSFYRRLTEDKKSEKFFRVFYERMKAAQQEIKATVTVNTAELGGESKE----------------------DDGA---EKDLPSVSHS-----------------TAGGSGATASGFGEGGGGERATYVESDEISPLISIMEPILRFLQLLCENHNPALQNFLRCQN-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINERNVGLINQTLESLTEYCQGPCHENQNCIATHESNGIDIIIALILNDINPLGKDRMELVLELKDNASKLLLAIMESRHDSENAERILYNMRPKELVAVIKKAYHQEGEESEDGVVEEQS-----------TSPKEVGHNIYILAHQVGTGEVNSARHLSETLTGLKDMSSPSLAAQLARHNKELDQMLHLSSSQGEEGSEALDYYTKHTSQIEIVRHDRVMEEIVFPVPNVCEFLTSQSKTRVYLTTERDDQGSKISDFFQSSHELFSEMVWQKQLRGRALLFLAVALPVVWGTISSNLTVFMNLLVAFFYPFNSSSGGGTLPLRLSGLLWLAVLVVLALVVLLPRPHSVRALVVVVILRLIFSVGCQPILILLGTANVLNKVVFLVSFVGNKGTFTHGYQAMVMDVEFLFHLSYLIICALGLVMHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGFLFLKDDFVMEVDRLPALTVHSRGTRHSAISPRPFAHGFSTVSSWTRVERMNCLFCPLPHYLQRATSVTQTARTVRTQPETISTVICCTGVTSNTTHQIRCLHQPGGQEPLFVARVIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICAAGLERDKFDNKTVSFEEHIKVEHNMWNYLYFIVLIKVKDPTEYTGPESYVAQMIREENVDWFPRMRAMSLVSSEGEGEQNEMRVLQEKLEMTARLISGLCSQLSELKEQV 898
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003582.1 (pep scaffold:Pmarinus_7.0:GL477251:10655:41631:-1 gene:ENSPMAG00000003274.1 transcript:ENSPMAT00000003582.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 478.019 bits (1229), Expect = 1.311e-152 Identity = 240/375 (64.00%), Postives = 288/375 (76.80%), Query Frame = 3
Query: 171 LVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQG--AQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEI-----------------DKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHST 1238
LVDDRCVVQP GDL NPPKKFRDC F++CPM+R+SAQKQF A K + TDSLL+ KL AA+LEK QNE E+KKL+GTV+QYG V+QLLH+KSNK +TVNKRLPALLEKNAMRV L+ +GNEGSWF VQPFYK +MGD+VVVGDKV LNPVNAGQPLH S+Y+L+D+ GCKE+N+V+C+TSW+I+LF+ + EN +D+LKGGDVVRLFHAEQEKFLT DEY+K Q+VFLRTTGR +ATSATSSKALWE+EVV D CR GAG W+SLFRFKHLATG YLAAE+ D P + D +F LV + +D+ SIFE+DPT R D VPR+S+VR+++ CT WVHST
Sbjct: 13 LVDDRCVVQPDVGDLGNPPKKFRDCLFRMCPMNRYSAQKQFLKAAKPAIHSSTDSLLLKKLQHAADLEKKQNESENKKLLGTVIQYGNVVQLLHMKSNKYMTVNKRLPALLEKNAMRVVLNGSGNEGSWFYVQPFYKLRSMGDSVVVGDKVVLNPVNAGQPLHASNYELVDNPGCKEVNSVNCSTSWKISLFMTWSENKEDILKGGDVVRLFHAEQEKFLTSDEYRKKQHVFLRTTGRQSATSATSSKALWEIEVVQHDPCREGAGHWNSLFRFKHLATGDYLAAEVTAWAPRNVSVPPPPRRSQADAEPAASSTSRSSKRDRMMFTLVPVDHGSDIASIFELDPTTMQRGDSLVPRNSYVRLRHLCTNTWVHST 387
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007822.1 (pep scaffold:Pmarinus_7.0:GL476823:160879:181935:-1 gene:ENSPMAG00000007060.1 transcript:ENSPMAT00000007822.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 325.094 bits (832), Expect = 1.285e-98 Identity = 184/402 (45.77%), Postives = 248/402 (61.69%), Query Frame = 3
Query: 6966 SVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGI-------------------------------------------GDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICA--LNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQM 8030
SV V +I+++ F + P L+ +G N++N ++F++S GN+G + + + EFL H S +I LGL++H FYS+ L DL+ REETLLNVI+SVT+N RS+VLT +L +IL Y F+I G LF +DDF ME + L ++ + S G T+ LT LY R GG G++ R P E F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFICA L R FDNKTV+FEEH + EHNMW+YLYFIVLIKVKDPTE+TGPESYV++MI+ +N+DWFP+ RAMSL + E E EQN+++ LQ +LE T ++IS L QL+ELK Q+
Sbjct: 50 SVRALVVVVILRLIFSVGCQPILILLGTANVLNKVVFLVSFVGNKGTFTHGYQAMVMDVEFLFHLSYLIICALGLVMHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGFLFLKDDFVMEVDRLPALT--VHSRG------LNSTVPEDLTVVLYLNERGGGAFSGMKKKLGVGQNEWRLSQKRNCHLMPSAILSIGVHFMMSLSLGGEVYRAPPRVEPLFVARVIYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICAAGLERDKFDNKTVSFEEHIKVEHNMWNYLYFIVLIKVKDPTEYTGPESYVAQMIREENVDWFPRMRAMSLVSSEGEGEQNEMRVLQEKLEMTARLISGLCSQLSELKEQV 443
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010602.1 (pep scaffold:Pmarinus_7.0:GL476450:29:322425:-1 gene:ENSPMAG00000009553.1 transcript:ENSPMAT00000010602.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 72.4034 bits (176), Expect = 1.658e-12 Identity = 61/222 (27.48%), Postives = 100/222 (45.05%), Query Frame = 3
Query: 363 LEKTQNEIEHKKLVG--TVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSL--DSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLA 1016
L T+ + E L G + YG I L H S L+ + + +K A V L D+ G E W+ + P K + G+ V VGD + L +++ + LH+S + G ++A T W ++ E L GGDV+RLFH E + D++ R+ + +++LW +E + + + G W FR +H+ TG+YLA
Sbjct: 66 LANTEEKAEGTALGGGHRTLLYGHAIILRHAHSGMYLSCLRTSHSSSDKLAFDVGLQEDTTG-EACWWTIHPASKQRSEGEKVRVGDDLILVSISSERYLHLSHAN-----GSLHVDASFQQTLWNVSPVCSGSEMAQGYLIGGDVLRLFHGHDECVTVPPADRGDEH--RRSVHYEGGAVCSHARSLWRLETL-RVSWSGNHLHWGQPFRLRHVTTGKYLA 278
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Nematostella
Match: EDO37876 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEK1]) HSP 1 Score: 2599.31 bits (6736), Expect = 0.000e+0 Identity = 1423/2733 (52.07%), Postives = 1867/2733 (68.31%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATK-QGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIK--HLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSE--NFP-IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD-----FSAI--PMKVTQLDLDIESQKP--------------GSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE------------NEIDISKICQQAEDIFSEKDNVYEIDLD--GEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP----KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLT-IKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFG--------NKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAAD-GNSQNSL-ENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDS-----YTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENW---PATN 8096
SFLHIGDI+SLYAEGNV+GF+STLGL+DDRCVVQP AGDL NPPKKFRDC FKICPM+R+SAQKQFW A K + TD++L+ KLH AAELEK QNE E+KK++ +VVQYG+V+QLLH+KSNK LTVNKRLPAL EKNAMRV+LD NGNEGSWF + PFYK A GDNVVVGD V LNPVNAGQPLH S+ +L+D+ GCKE+N V+C TSW+I+LFL Y EN +D+LKGGDVVRLFHAEQEKFLTCD++KK Y+FLRTT R TATSATSSKALWEVEVV D CRGGAG W+ LFRFKHLATG YLAAE D D T D R KL+ G D VF LV P ND+ SIFE+DPT TRSD VPR S+VR+++ CT WVHST IPIDK E++P+M K+G A +KEDKEAFAIV V A EVRDLDFAND SKVL K++ + T ++++ V LL+ +++F+ + G D L+++V++ +RDRQKL+REQNILK++F +L++P ++ N P +++++L+DQ++ R+I RLCYR+L+ SQQDYRKNQEYIAKQ MQ QIGY ILAEDTIT L+HNNRKLLEKHIT +EI TF++L+RK K+ RFL +LSDLC+SN+ AIP TQELICK + H +N D+L++T + D+L V + K E + + W+ G++ K +++ K+D IL YYRYQLNL+S MCLDRQYLAIN +S +L + LIL+C+A+ P +LRA+FCRLM+H+H+DRDPQE VTPV+YARLW++IP +M I YD + E++E+++ F V+ FVE YL+NI++N FS++EQNKLT E+V +A+HLIYFGFY F D LRL +TLL ILD F+ I K D +E K GS + + D+ ++M TKL+ IEIL+FI+NVRLD++I+ LL IFK F+ N ID+ I QAE IF +IDLD G+GG+ FLRVLL L MH YP++V+G+LQ+L RHF+QRQEVLQ FKQVQLLVST+DVENY+QI++DLD LRLLVEKSELWVYK+K K+S+ ++ E+A G + K ++IL+R+ LC + P K+RKHEQRLL+NMGAHTV++ELLQIP+ K DI+M++I+ALAH FLQ FC GN NQ +LHK+ DLFLTPG L E++T+ I+ DN LC V E+VVQH + CIE+ G V +LK LQT++KA+ Q IRK QDMV++EL++VG++VLVFY+D F HLI MM+S+R +L G L YHI LV+LLA TEGKNVY+EIKCHSLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N +W LF L+D+A+V ++ + D LE+ VT TIM +I FFNSPFS+ +T IK++Q + LL+ FR+ QC+WL+ QK ++ +K + +I K + I IP +LE QI + Q ++KH++ WL+ K ++DS ++ + RS+I+ L D + LE QL+PL+QAE S+LV V ++P+L+F H+EAR K GGF++RL+ HT+ LL NE LCI+VLQTL+ M++ D +F +K LR LL +Y+G K S+ L +S++ S P + R+ ++ ++Q +LD+ G S+LIIDLI+ + N R+F+EI+E IALLEGGN +QKSF R DK + FF +T+A EIK+ I + A G + L E + + +R+QL DAA +N+A +AVR+S + D E ++S ++ R VI ++PI RFLQLLCENH R+LQ+ +R Q NK +YNLV ETLQFLDCICGSTSGGLGLLGLYINE+NV LINQ L +LTEYCQGPCH+NQ+AIA+HESNGIDIIIAL+LNDINPLG+ RMDLVLELK+ ASK LLA++ESRHDSENAERIL N++PKQLVDV K A+ +D +++ DD SE S ++VGHNIY+LA QLS+H +ELA LL+ + + D ALEYYAK+TAQIEIVR DR+ME+IVFP+P+ICE++T+E+K V E D+Q SKV FF T +FQEMQWQK LR LLF +S+ + LW I+ F +++N+L+ +YPF + + ++WL +++S + + FV + I+++ F L + P L +G N++N I ++S GNRG + I + E ++H + VLGL VH FYSV LLD+I RE+TLLNVIRSVT+N RS++LT IL +I+ Y F+I G LF +DDF +E + + IG G+ KER CDTL MC+ TTL QGLRNGGGIGD+LR+ S KEK F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ K+E+L+NTCFIC L+RSAFDNK+V+F+EH + +HNMWHYLY+IVL++VKDPTEFTGPESYVS M K KNLDWFP+ +AMSLA DE EQN++++LQ +LE T +++ LS QL++LK QMTEQRKQKQR LL P++ P TN
Sbjct: 6 SFLHIGDIVSLYAEGNVTGFISTLGLIDDRCVVQPGAGDLSNPPKKFRDCLFKICPMNRYSAQKQFWKAAKPTTSATDAVLLKKLHHAAELEKKQNESEYKKMLSSVVQYGSVMQLLHVKSNKFLTVNKRLPALREKNAMRVTLDPNGNEGSWFYIVPFYKLRAAGDNVVVGDMVILNPVNAGQPLHASNQELIDNPGCKEVNCVNCQTSWKISLFLSYDENDEDILKGGDVVRLFHAEQEKFLTCDDFKKKSYIFLRTTARQTATSATSSKALWEVEVVQHDPCRGGAGHWNCLFRFKHLATGDYLAAEADDDNTKDATRHKLK--GSDPVFHLVPAPHGNDIASIFELDPTTLTRSDSLVPRCSYVRLRHLCTNTWVHSTGIPIDKGEERPVMLKIGTASIKEDKEAFAIVPVPALEVRDLDFANDASKVLGTFASKLETGNYTQHERRFVTQLLTDLVYFVTEHDTGGEDVLNIQVQDPNRDRQKLMREQNILKEVFHLLKAPFTDKGNGPMLRIEELSDQRNAPLRHIFRLCYRVLRHSQQDYRKNQEYIAKQFGFMQAQIGYDILAEDTITDLVHNNRKLLEKHITRTEIETFVSLVRKKKEC--RFLDYLSDLCVSNHTAIPATQELICKTVLHPSNSDLLIETSM---------------------GDVLLVWEMNNGKR----CVPGLGEYVFLVWERGEKMKAQKDIAKGVKMMVKEDIKILDYYRYQLNLFSQMCLDRQYLAINSISKQLDVDLILRCMADKELPCDLRAAFCRLMLHMHIDRDPQETVTPVKYARLWSEIPTEMTIHVYDQHEAVGEEREDIRRRFEGVIQFVENYLHNISSNVFSFSDKEQNKLTFEVVQIARHLIYFGFYGFSDLLRLTQTLLSILDCEQRAFTRIHNGGKNDVNDNKVEMTKSIHLLGATMTRVAFGGSLDPWGLIQHSEGGTKGEIEIDH-VVMETKLKVIEILEFIMNVRLDYRISSLLTIFKKDFDESNANIGDVNADNGIDLENISAQAEAIFGGSIGSADIDLDLDGQGGRTFLRVLLYLCMHDYPSLVTGSLQLLIRHFSQRQEVLQAFKQVQLLVSTSDVENYKQIRSDLDELRLLVEKSELWVYKSK-------------------------KDSIGSTKKKKETAD----GDNDKEALDKQDKAAQQILQRISQLCVTYGPDDVKKNRKHEQRLLRNMGAHTVVLELLQIPYAKDEDIRMEDIMALAHEFLQNFCLGNPQNQSLLHKHLDLFLTPGLL-----------ESQTLRYIFMDNSALCYEVTERVVQHIIHCIESRGRHVEYLKLLQTLVKAEGQSIRKTQDMVMAELVNVGEDVLVFYSDTKSFNHLIEMMQSERERLDEAGALLYHINLVQLLACCTEGKNVYTEIKCHSLLPLDDIVRVVTHEDCIPEVKNAYVNFLNHCYVDTEVEMKEIYTSNH-IWRLFEDFLVDMARVCNNMMDRYHADTMLEKYVTETIMNLITFFFNSPFSDASTTIKSRQPVFVKLLRGAFRVSQCSWLSGAQKYHVETCIKALSDIAKNRNIAIPGDLETQIQALFTRSQLVMKHTRHWLSHGKVRRDS--------TMHLSRDYRSIIEGLQDIVSLLEDQLRPLIQAESSLLVDVLYKPDLMFPGHSEARQKAGDGGFVTRLVNHTKRLLQDNE-VLCIRVLQTLKAMMARDTDFGEKGETLRVSLLKRYYGANYAMTRDKKRSRERLSRKTSSQSCN-SGPGATLLSRA--GVTLFEMQCHLDACGTSDLIIDLIVA-TPNHRIFQEIMELAIALLEGGNGVIQKSFLHRFLTDKLCEGFFNYMMERMTDAAAEIKANITIGARVGIGEGGLFELRQASISYGSLTGVSEEIREQLMDAAAHTNKAYLAVRRSRDP-------------------DTETETPSLSGTSAQQSISVLIRCQQKVIAMKPILRFLQLLCENHNRDLQNYIRRQDNNKANYNLVHETLQFLDCICGSTSGGLGLLGLYINENNVELINQCLESLTEYCQGPCHDNQDAIARHESNGIDIIIALVLNDINPLGKQRMDLVLELKNTASKTLLAVMESRHDSENAERILYNMTPKQLVDVCKQAYQQDDMVEEDD--SE-------------VSARDVGHNIYLLATQLSQHNKELASLLKLTHTEFEMEQIHGDSALEYYAKNTAQIEIVRQDRTMEQIVFPVPQICEFLTDESKINVYATCERDDQNSKVSDFFHRTEDLFQEMQWQKKLREHRLLFGLSSRLSLWEQISINFAVLINLLVGFFYPFSDGPGDLDPRLSILVWLAMLVSFAIIITFPRPSGIRTFVGSTILRLIFSLGLEPTLRILGLANVINKAISVVSFVGNRGTFQYGVRRILTDKELILHLTYFGFGVLGLTVHTFFYSVLLLDVIFREDTLLNVIRSVTRNGRSIILTGILALIIVYMFSIVGFLFLKDDFLIETDPPPALPS-IGEGGESVKERACDTLIMCIVTTLNQGLRNGGGIGDVLRRRSSKEKMFAGRVVYDLMFFFIVIIIVLNLIFGVIIDTFADLRSEKQNKEEVLKNTCFICGLDRSAFDNKSVSFDEHIKSQHNMWHYLYYIVLLRVKDPTEFTGPESYVSHMTKDKNLDWFPRMQAMSLAIDEGGNEQNEMRNLQDKLENTTKLVQTLSQQLSDLKEQMTEQRKQKQRMGLLGPQHGLAAPPTN 2619
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Nematostella
Match: EDO28592 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T616]) HSP 1 Score: 800.431 bits (2066), Expect = 0.000e+0 Identity = 436/778 (56.04%), Postives = 561/778 (72.11%), Query Frame = 3
Query: 5814 LSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQND-----SYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDI--NSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQME---PEFL--------DIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPAT 8093
++ VI ++PI RFLQLLCENH R+LQ+ +R Q NK +YNLV ETLQFLDCICGSTSGGLGLLGLYINE+NV LINQ L +LTEYCQGPCH+NQ+AIA+HESNGIDIIIAL+LNDINPLG+ RMDLVLELK+ ASK LLA++ESRHDSENAERIL N++PKQLVDV K A+ +D +++ DD SE S ++VGHNIY+LA QLS+H +ELA LL+ + + D ALEYYAK+TAQIEIVR DR+ME+IVFP+P+ICE++T+E+K V E D+Q SKV FF T +FQEMQWQK LR LLF +S+ + LW I+ F +++N+L+ +YPF + + ++WL +++S + + FV + I+++ F L + P L +G N++N I ++S GNRG + I + E ++H + VLGL VH FYSV LLD+I RE+TLLNVIRSVT+N RS++LT IL +I+ Y F+I G LF +DDF +E P L + + G G+ KER CDTL MC+ TTL QGLRNGGGIGD+LR+ S KEK F RV++DL F+FIV +I+LNLIFGVIIDTFA LR KQ K+E+L+NTCFIC L+RSAFDNK+V+F+EH + +HNMWHYLY+IVL++VKDPTEFTGPESYVS M K KNLDWFP+ +AMSLA DE EQN++++LQ +LE T +++ LS QL++LK QMTEQRKQKQR LL P++ A
Sbjct: 1 MAPEVIAMKPILRFLQLLCENHNRDLQNYIRRQDNNKANYNLVHETLQFLDCICGSTSGGLGLLGLYINENNVELINQCLESLTEYCQGPCHDNQDAIARHESNGIDIIIALVLNDINPLGKQRMDLVLELKNTASKTLLAVMESRHDSENAERILYNMTPKQLVDVCKQAYQQDDIVEEDD--SE-------------VSARDVGHNIYLLATQLSQHNKELASLLKLTHTEFEMEQIHGDSALEYYAKNTAQIEIVRQDRTMEQIVFPVPQICEFLTDESKINVYATCERDDQNSKVSDFFHRTEDLFQEMQWQKKLREHRLLFGLSSRLSLWEQISINFAVLINLLVGFFYPFSDGPGDLDPRLSILVWLAMLVSFAIIITFPRPSGIRTFVGSTILRLIFSLGLEPTLRILGLANVINKAISVVSFVGNRGTFQYGVRRILTDKELILHLTYFGFGVLGLTVHTFFYSVLLLDVIFREDTLLNVIRSVTRNGRSIILTGILALIIVYMFSIVGFLFLKDDFLIETDPPPALPSIGSPRGGVCASSGGEGGESVKERACDTLIMCIVTTLNQGLRNGGGIGDVLRRRSSKEKMFAGRVVYDLMFFFIVIIIVLNLIFGVIIDTFADLRSEKQNKEEVLKNTCFICGLDRSAFDNKSVSFDEHIKSQHNMWHYLYYIVLLRVKDPTEFTGPESYVSHMTKDKNLDWFPRMQAMSLAIDEGGNEQNEMRNLQDKLENTTKLVQTLSQQLSDLKEQMTEQRKQKQRMGLLGPQHGLAA 763
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Nematostella
Match: EDO29741 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2S4]) HSP 1 Score: 155.221 bits (391), Expect = 7.148e-44 Identity = 83/110 (75.45%), Postives = 96/110 (87.27%), Query Frame = 3
Query: 597 VVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVE 926
VVVGD V LNPVNAGQPLH S+ +L+D+ GCKE+N V+C TSW+I+LFL Y EN +D+LKGGDVVRLFHAEQEKFLTCD++KK Y+FLRTT R TATSATSSKALWEVE
Sbjct: 5 VVVGDMVILNPVNAGQPLHASNQELIDNPGCKEVNCVNCQTSWKISLFLSYDENDEDILKGGDVVRLFHAEQEKFLTCDDFKKKSYIFLRTTARQTATSATSSKALWEVE 114
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Medaka
Match: itpr1b (inositol 1,4,5-trisphosphate receptor type 1 [Source:NCBI gene;Acc:101155104]) HSP 1 Score: 2600.47 bits (6739), Expect = 0.000e+0 Identity = 1414/2756 (51.31%), Postives = 1894/2756 (68.72%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQ--TDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKD---PTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW-DNGK--QSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILD------------FSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFE----------NEI-------DISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLC---ESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHS-KAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIIL-AADGNSQNSLENVMPR----RRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENN--HPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGK---------------IGSDGDP-----------EKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL-RPENWPATNQQ*A 8108
SFLHIGDI SLYAEG+ SGF+STLGLVDDRCVVQP AGDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K G TD++L+NKLH AA+LEK QNE E++KL+GTV+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV+LDS GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW++ LF+++ +N + +LKGGDVVRLFHAEQEKFLTCD++KK Q+VFLRTTGR +ATSATSSKALWEVEVV++D CRGGAG W+SLFRFKHLATG YLAAE++ D + +R +LR + + LV +P +++SIFE+DPT D VPRSS+VR+K+ T WVHST+ PIDKEE+KP+M ++G + +KEDKEAFAIV V EVRDLDFAND SKVL+ + K++ TI N+++ V LL ++FF+ + +SG D L++ V + +R+RQKL+REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF+ L+RK ++ RFL +LSDLC+S + +IP+TQELIC + NN DIL++T+ FE +E + + + + E+EEE+ + W DN K +SK+++EL A K+D+ +++YYR QLNL++ MCLDRQYLAIN +S++L + LIL+C++++ P +LRASFCRLM+H+HVDRDPQE VTPV+YARLW++IP K+ ID+YD+ + ++E+K F M FVE YL + + N+ F+++E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + +TQ+ L P + + + + ++ ++M+TKL+ IEILQFILNVRLD++I+CLLCIFK F+ N+I D I +QAE IF + +DLD GG+ FLRVLL+L MH YP +VSGAL +LFRHF+QRQEVL FKQVQLLV++ DV+NY+QIK+DLD LR +VEKSELWVYK + ED + D ++ +N S +SA++ NY +KEIL RL LC S KS+K +QRLL+NMGAH+V++ELLQIP++K D++MQ+I+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + E+VVQH+V C E+HG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L+ MM S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI +V H C VK AY+ FL HCY+DTEVE+K+I++ N MW LF L+DI +V T ++ D LE VT T+M ++ FF+SPFS+Q+T ++ +Q + LLQ VFR+Y C WL QK ++ +K + ++ K++ I IP +L+ Q+N +K +++ S W L+ KN ++DS PS + R++I+ L D + ALE +L+PL+QAE+SVLV V HRPELLF +TEAR KCESGGFIS+LIKHT+ LL NEE+LCIKVLQTLR M++ D F +K LRQ L+ +Y+GN K V+ + + LS ++Q +LD +GAS+L+IDLI++ +S +R+F+E I IALLEGGNT +Q+SFY+RL D S+KFF+ F+ + AQ EIK+ + + +D S+ E + + +R R +++QL +A+ + +A R+ I + + +++ +S + I++PI R +QLLCENH R+LQ+ LR+Q NK +YNLVCETLQFLDCICGST+GGLGLLGLYINE NVGLINQ + +LTEYCQGPCHENQN IA HE NGIDIIIALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV + LA P E GE G S ASP+ VGHNIYILAHQL++H +EL +L+PG D+ALE+YAKHTAQIEIVR DR+ME+IVFP+P ICE++T+E+K +V TE DEQGSK+ FF + +F EM WQK LRA+ +L+W S +M WS I+F ++MNIL+ +YP P+ + +++W+ +++SL + + + + + I+++ F + + P LL +G N N +IF+ S GNRG + + ++ EFL H +I LG+ VH FYS+ L DL+ REETLLNVI+SVT+N RS+VLT +L +IL Y F+I G++FF+DDF + +D I K + S P +KER CD+L MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYL+FIVL+KVKD TE+TGPESYV+EMI+ NLDWFP+ RAMSL + + + EQN++++LQ +LE T ++++NLS QLTELK QMTEQRKQKQR LL +P + QQ A
Sbjct: 7 SFLHIGDICSLYAEGSTSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGGNSTTDTVLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSLGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKVVLFMKWSDNKETILKGGDVVRLFHAEQEKFLTCDDHKKKQHVFLRTTGRQSATSATSSKALWEVEVVHRDPCRGGAGYWNSLFRFKHLATGCYLAAEVNPDFEEENNEALRGRLRTPQEKVMCTLVPVPDGMEISSIFELDPTTLRGGDSMVPRSSYVRLKHLFTNTWVHSTNNPIDKEEEKPVMLRIGTSEVKEDKEAFAIVPVPPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRFVTKLLEDLVFFVVDIPNSGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVTLVRKNREP--RFLDYLSDLCVSMSKSIPVTQELICNAVLDSNNADILIETK-------------------FE---------IETSTNGDIPLQAEDEEEVWLFWKDNAKDIRSKSVRELAQDAREGQKEDQEVVSYYRCQLNLFARMCLDRQYLAINKISNQLDVDLILRCMSDEDLPFDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSKIAIDDYDN---DGNSRDEIKERFSLTMDFVENYLREVVSQNIPFTDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLNILDCVHVTGSNVMKSIHGVGELMTQVVLRGGGLLPTA--PAHQPEGEVVKTQTEPEREDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKCEFDENNPPGENAPNQIPSLTGNFDFENIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDLDQLRSIVEKSELWVYKRQ------------GEDGMDGDGPSESENKKKVSR--TKSAVDNSY----------NYRVVKEILIRLSKLCVQEGSTGKKSKKQQQRLLRNMGAHSVVLELLQIPYEK--DVRMQDIMKLAHEFLQNFCAGNQPNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINERVVQHFVHCTESHGRHVQYLKFLQTIVKAENKFIKKCQDIVMAELVNSGEDVLVFYNDRASFQTLVQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFENFLVDICRVCNTTSDRKHADTMLERYVTETVMSIVTCFFSSPFSDQSTSLQTRQPVFVQLLQGVFRIYHCNWLNPVQKASVEACIKVLSDVAKSRAIAIPVDLDSQVNNLFVKSNNVVQKSILNWRLSAKNTSRRDSC------PSTSK--DYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTEARKKCESGGFISKLIKHTKQLLEENEERLCIKVLQTLREMMTKDGGFGEKGEALRQILVNRYYGN--VKAVVSSGVGGRGD----------------LSLAEVQCHLDKEGASDLVIDLIMNATS-DRIFQESILLAIALLEGGNTVIQRSFYQRLTTDNKSEKFFKVFNERMKLAQQEIKATVTVNTSDLGSKKKDEEPPDKGTCGQDIRWRETPLPEVKEQLVEASTVTKKAYTTYRREAEAEEHQAAADGSPIPTV-------------------DKSQDEGEMSVIITIMQPILRLMQLLCENHNRDLQNFLRYQN-NKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVGLINQTVESLTEYCQGPCHENQNCIATHECNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVRLMSLASSHGE-------PQE--GEDGEEEHS--ASPRNVGHNIYILAHQLARHNKELQAMLKPGGTYGEGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPNICEFLTQESKLRVYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPILYWCSRNMSFWSSISFNLAVLMNILVAFFYPLEGVRGGTLEPH-LSALLWIAMLVSLAIVIVLPQPHGIRALIASTILRLIFSVGLEPTLLLLGGFNFCNKVIFLTSFVGNRGTFTRGYKAMIMDVEFLYHLLYLIICGLGVFVHVFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIFFKDDFILA---VDRIPNKTLGTTEAHFQLNTLTLSSQPCPKLSFHPSVVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIREHNLDWFPRMRAMSLVSSDADGEQNEIRNLQEKLESTMKLVTNLSSQLTELKEQMTEQRKQKQRIGLLGQPAHMNINPQQPA 2627
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Medaka
Match: itpr1a (inositol 1,4,5-trisphosphate receptor type 1 [Source:NCBI gene;Acc:101167700]) HSP 1 Score: 2530.36 bits (6557), Expect = 0.000e+0 Identity = 1380/2759 (50.02%), Postives = 1872/2759 (67.85%), Query Frame = 3
Query: 96 SFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEID---KDPTPD----LMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTI--NDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFP---IKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXW----DNGKQ---SKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIP------------------MKVTQLDLDIESQ---KPGSFKEXXXXXXXXXXXXXXX---DADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHF---------------------ENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDP---KSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAIL-KHSKAW-LTIKN--KKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPR----SFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVS-VIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFL-DIISGKIGSDG----------------------DPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
SFLHIGDI SLYAEG+ +GF+STLGLVDDRCVVQP AGDL+NPPKKFRDC FK+CPM+R+SAQKQFW A K G TD++L+NKLH AA+LEK QN+ E+KKL+G+V+QYG VIQLLH+KSNK LTVNKRLPALLEKNAMRV LD+ GNEGSWF +QPFYK ++GD+VV+GDKV LNPVNAGQPLH SS+ L+D+ GC E+N+V+CNTSW+I LF+++ +N + VLKGGDVVRLFHAEQEKFLTCD+++K QYVFLRTTGR +ATSATSSKALWEVEVV D CRGGAG W+SLFRFKHLATG YLAAE++ ++ PD +R++LR + + ++ LV++P ND++SIFE+DPT D VPR+S+VR+++ CT WVHST+ PIDKEE+KP+M ++G + KEDKEAFAIV VS EVRDLDFAND SKVL+ + K++ TI N+++ V LL ++FF+ + ++G D L++ V + +R+RQK++REQNILKQIFK+L++P +++ +++++L DQ+H FR+ICRLCYR+L+ SQQDYRKNQEYIAKQ MQKQIGY +LAEDTITALLHNNRKLLEKHIT +EI+TF+NL+RK ++ RFL +LSDLC+S N +IP+TQELIC + N DIL++T++ FE + GV P E EE+ W +N K+ SK+++EL A K+D+ +++YYRYQLNL++ MCLDRQYLAIN +S +L + LIL+C++++ P +LRASFCR+M+H+HVDRDPQE VTPV+YARLW++IP K+ I++YD+ + K+E+K F M FVE YL N+ + NL F N+E+NKLT E+VNLA++LIYFGFY F D LRL K LL ILD + M+ ++ SQ + G F ++ N + KT + + L+M+TKL+ IEILQFILNVRLD++I+CLL IFK F + +D + +QAE IF + +DLD GG+ FLRVLL+L MH YP +VS AL +LFRHF+QRQEVLQ FKQVQLLV++ DVENY+QIK+DLD LR +VEKSELWVYK +L D+ + L+ H K + G K + T NY +KEIL RL LC + P K+RK +QRLL+NMGAH V++ELLQIP++K D++MQ+I+ LAH FLQ FC GN+ NQ +LHK+ +LFL PG L EA TM I+ +N +LC+ + ++VVQH+V CIETHG V +LKFLQTI+KA++++I+KCQD+V++EL++ G++VLVFYND F L++MM+S+R ++ N PL YHI LV+LLA+ TEGKNVY+EIKC+SLL ++DI IV + C VK AY+ FL HCY+DTEVE+K+I++ N MW LF+ L+DI +V ++ D LE+ VT T+M ++ TFF+SPFS+Q+T ++ +Q + LLQ V+R+Y C WL QK + +K + ++ K++ I IP +L++Q+N +K +++ K + +W L+++N ++DS T P+ +N +I+ L I L + + E+ +C+F RLIKHT+ LL NEEKLCIKVLQTLR M++ D + DK LRQ L+ +Y+GN + + + ++ +P+ + S ++S ++Q +LD +GAS+L+IDLI++ +S +RVF+E I IALLEGGNT +Q SF+ RL DK S+KFF+ F + AQ EIK+ + + + + L N P +++ + A E+ + + S + + + ++ + + D + ++ + + ++ +S ++I++PI RFLQLLCENH R+LQ+ LR Q K +YNLVCETLQFLDCICGST+GGLGLLGLYINE NV LINQ L +LTEYCQGPCHENQN IA HESNGIDIIIALILNDINPLG+ RMDLVLELK+NASKLLLAI+ESRHDSENAERIL N+ PK+LV+V K A+ + +++ ++ + D ASP+ VGHNIYILAHQL++H +EL+ +L+PG D+ALE+YAKHTAQIEIVR DR+ME IVFP+P ICE++T E+K +V TE DEQGSK+ FF +F EM WQK LRA+ +L+W S +M +WS+I+F ++MN+L+ +YP + +S ++W+ + +L + + + + V I+++ F + + P L +G N+ N IIF+IS GNRG + + ++ EFL H +I LG+ H FYS+ L DL+ REETLLNVI+SVT+N RS+VLT +L +IL Y F+I G++FF+DDF +E + + +I +DG D ER CD+L MC+ T L GLR+GGG+GD+LRKPS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ+K+E+L+ TCFIC L R FDNKTVTFEEH EH+MWHYLYFIVL+KVKD TE+TGPESYV++MIK NLDWFP+ RAMSL + + E EQN+++SLQ +L+ T ++++NLS QLTELK QMTEQRKQKQR LL
Sbjct: 7 SFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGGNTDTVLLNKLHHAADLEKKQNDSENKKLLGSVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVMLDTAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWGDNQEVVLKGGDVVRLFHAEQEKFLTCDDHRKKQYVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPEYEEERPDNQHEALRARLRCAQEKVMYALVAVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLRIGTSPHKEDKEAFAIVPVSPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRAVTKLLEDLVFFVVDIPNNGQDVLEIMVNKHNRERQKVMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVNLVRKNREP--RFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKL--------------VLSRFE------IQGV-----PLGENSVESEEDEEEVWLFWKENNKKEIRSKSIRELAQDAKEGQKEDKEVISYYRYQLNLFARMCLDRQYLAINKISCQLDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPLKISIEDYDN---DGTSKDEIKERFSQTMEFVETYLRNVVSPNLSFGNKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLGILDCVHVGAIYSFNKQEKEDSKGSNVMRSIHGVGELMSQVVLRGGGFLPTTTVNTSNGEAVKTQIEPEKQDILVMDTKLKIIEILQFILNVRLDYRISCLLSIFKTEFDERNSQSDLSINGVIESQNNMQGALDFEHMEEQAEGIFGGSEQNNPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVYK-RLGPDE-----GMDGGDALASEHKK-----------------VHWGKKTESTSSYNYRVVKEILLRLSKLCVQEGPTGRKNRKQQQRLLRNMGAHAVVLELLQIPYEKGEDLRMQDIMKLAHQFLQNFCAGNQQNQALLHKHINLFLNPGIL-----------EAVTMQHIFMNNFQLCSEINDRVVQHFVHCIETHGRNVQYLKFLQTIVKAENKFIKKCQDIVMAELVNAGEDVLVFYNDRASFQTLVHMMQSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRIVTNEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNH-MWKLFDNFLVDICRVCNNTSDRKHSDVILEQYVTETVMSIVTTFFSSPFSDQSTSLQTRQPVFVQLLQGVYRVYHCQWLIPTQKGFVESCIKVLSDVAKSRTIAIPVDLDNQVNNLFVKSNSLVQKTAMSWRLSVRNAARRDSVVT--SSPNYRN------IIERLQVQIYILGCCIPCKICREIEDFLCIF------------------------RLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGDKGEALRQILVSRYYGNFHQSSGRRDSLTSFGNSHLSPVGPVLGGHGGLSRGEMSLTEVQCHLDREGASDLVIDLIMNATS-DRVFQESILLAIALLEGGNTTIQHSFFCRLTDDKKSEKFFRVFYDRMKSAQMEIKATVTV-----NTSDLGNKKPDEDDQEKEVTVGKKVTESGVAMTENAKEQLLEASSATKKAFSSYRRHTDPDEHFPATDGQPSSGDKN--------QDEGEMSFVIVIMQPILRFLQLLCENHNRDLQNFLRCQN-KKNNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIIIALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMKPKELVEVIKKAYLQG---EIEFEDAKEEDDDIDEEEHDAASPRNVGHNIYILAHQLARHNKELSMMLKPGGAGGEGDEALEFYAKHTAQIEIVRQDRTMEEIVFPVPNICEFLTSESKLRVYYTTERDEQGSKINDFFLRAEDLFNEMNWQKKLRAQPVLYWCSRNMSVWSNISFNLAVLMNLLVCFFYPLEGVHGGMLDPHLSALLWIGVFATLAIVILMPQPLGIRALVFVTILRLIFSVGLEPTLFLLGAFNVCNKIIFMISFVGNRGTFTRGYKAMVMDFEFLYHLLYLIICCLGVFGHVFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIFFKDDFILEVDRIPNITLSADDADGELLSAVCHNGAGENCSTAVHEEDSNMERTCDSLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIMEEHSMWHYLYFIVLVKVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNEIRSLQDKLDSTMKLVANLSGQLTELKEQMTEQRKQKQRIGLL 2650
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Medaka
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192]) HSP 1 Score: 1438.71 bits (3723), Expect = 0.000e+0 Identity = 802/1667 (48.11%), Postives = 1093/1667 (65.57%), Query Frame = 3
Query: 3153 MHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQ--NGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNK--LSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMI---ILAADGNSQNSLENVMPRRRVRDRSN---IPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYE--DTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSY-TDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFP--AKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSE--FLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDG-------DPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPEN 8081
M YP +VSG+LQ++F+HF+QR E+LQ FKQVQLLVS DV+NY+QIKADLD LRL VEKSELWV K+ + S ++ +ED VLS + E D P+ID NY +KEIL+RL LC + KSR +QRLLKNMGAHTV+++LLQI +++ ND KMQ+I+ LAH FLQ FC GN NQ +LHK+ +LFLTPG L EAETM I+ +N +LCN + ++VV HYV CIETHG +LKFL+TI+K+ +Y++KCQD V++EL++ G++VLVFYND F L ++M S+R + +G L YH LV+LLA TEGKNVY+E+KC+SLL ++DI +V +C VK AY+ F+ HCY+DTEVE+K+I++ + +W LF+ L+D+A V T + + D LE+ VT +MG++ FF+SPFS ++V+++ Q+ I LLQ+ FRL C W T+ QK NI +KT+ ++ KA+ I IP +L+ Q+N LK A KD + + RP + G + +++ID L + LE Q PL+QAE SVLV V + PELLF P AR +CESG F+S+LIKHT+ L+ EEKLC+K+LQTLR M+ F++ N LR+ LL +YFGN+ LS++ L +++ S + +I + + + VDIQ LD GAS L+IDLI++ + N+ VF E I G+ALL GGNT Q SFY +L K S+KFF+ F + AQ EI++ + + ++ +V R + + + + +R QL +A+ +++A A RK L+ D E S +S +EI EE ++S ++ I++PI R+LQLLCENH +LQ+ LR+Q+ NKT+YNLVCETLQFLDCICGST+GGLGLLGLYINE NV L+ Q L T+TEYCQGPCH+NQ+ I +HESNGIDIIIALI+N INPL + R+DLV+ELK+NASKLLLAI+ESRHDSENAE+IL + P +LV+V K + + ++ D D++ S+ + ++VGHNIYILAHQL++H + L Q L+P Y + AL YYAKHTAQIEIVR DR+ME+IVFP+P ICEYITEE+K +V T TE D+QGSKV FF + + ++ EM+WQK +R +LFW S+H+ LW I+F+ ++N ++ +YPF E ++ +W + L +L F+ +LI++ + + +AP L +G +NL N ++F+ S GN+G + + + + F+ H + I VLGL VH FYS L DL+ REETLLNVI+SVT+N RS+ LT +L + L YFF+I G LF +DDF+ME + L + G D D ER CDTL MC+ T L QGLRNGGG+GDILR+PS +E F RV++DL F+F+V +I+LNLIFGVIIDTFA LR KQ K+EIL+ TCFIC L R FDNKTVTFEEH + EHNMWHYLYF+VL+KVKDPTE+TGPESYV++MI KNL+WFP+ RAMSL ++E + EQN+++SLQ +L T +IS LS QL ELK QMTEQRK KQR L P++
Sbjct: 1 MQDYPPLVSGSLQLIFKHFSQRAEMLQAFKQVQLLVSEQDVDNYKQIKADLDQLRLTVEKSELWVEKSGVYSSEELGVRLAEEDVVLSPVQ------------------EEDNKPQIDSNKGNNYNIVKEILQRLTKLC-NQSKKSRVQQQRLLKNMGAHTVVLDLLQIQYEQ-NDEKMQQIMTLAHTFLQNFCKGNHQNQVLLHKHLNLFLTPGLL-----------EAETMRHIFMNNYQLCNEISDRVVHHYVHCIETHGRHTKYLKFLETIVKSDGKYVKKCQDKVMTELVNAGEDVLVFYNDRSSFQVLKDLMRSERERSDEDGALAYHNTLVELLAACTEGKNVYTELKCNSLLPLDDIVKVVTEENCVPEVKTAYVNFVNHCYVDTEVEMKEIYT-SCHIWKLFDNFLVDMATVCNTTIDRNHADPLLEKYVTDAVMGIVKGFFSSPFSVNHSVLQSNQSTFIKLLQSAFRLTNCNWTTSAQKANIESCIKTLADVAKARAIAIPVDLDSQVNHLSLKIHTSTVQRAA-------KDWRISARSRPRKEPLGGPDYKNIIDKLQGVVSLLEEQFSPLVQAEFSVLVDVLYSPELLF-PEN-ARLRCESGIFMSKLIKHTKKLM-DKEEKLCVKILQTLREMLDQKECFNESGNELRKILLNRYFGNQKPLSRSELVSGNNS-----SGSTIMDIDKPCN--TMVDIQCLLDCVGASELVIDLIMN-TKNDLVFEESILLGVALLRGGNTQTQNSFYSQLSKQKKSEKFFKVFYDRMRLAQQEIRATVSVNMFELGSRKRDEDSDVSSNRFKKGKESGLYLREEMRGQLKEASSVTSKAFCAFRKELDS-------------------DLEGQTSEMSGT--EEIIEE-IQMSPAITIMKPILRYLQLLCENHNSDLQNFLRNQS-NKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINESNVDLVLQTLETITEYCQGPCHDNQSCIVKHESNGIDIIIALIINSINPLEKNRLDLVMELKNNASKLLLAIMESRHDSENAEKILYKMRPMELVEVMKEVYAQGLESEEDEDNIGSQ-------------ITSRDVGHNIYILAHQLARHNKLLQQCLRPSPGKEYDREDALHYYAKHTAQIEIVRHDRTMEQIVFPVPNICEYITEESKMRVFTTTERDDQGSKVNDFFQQFDNLYNEMKWQKKIRKNRVLFWFSSHISLWGSISFYLANLLNFVVATFYPFGDDGDEGTLSSMWNITLWASLGLFTALLPVFPKPWGILFFLVSLILRAIYTMGLAPALFLLGSVNLFNKLVFLASFVGNQGTFTRGYKAVVMDMLFVYHLAYAIICVLGLFVHEFFYSFLLFDLVSREETLLNVIKSVTRNGRSIFLTAVLAIFLVYFFSIIGFLFLKDDFRMEVDPLPL-PGHPSQDTCLCERCEDDGMERVCDTLLMCIITVLNQGLRNGGGVGDILRRPSKEEPLFAARVVYDLLFFFVVIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIAEKNLEWFPRMRAMSLVSNEGDNEQNEMRSLQEKLTNTVTLISQLSSQLAELKEQMTEQRKNKQRMGFLAPQS 1580
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Medaka
Match: itpr3 (inositol 1,4,5-trisphosphate receptor type 3 [Source:NCBI gene;Acc:101170574]) HSP 1 Score: 1365.9 bits (3534), Expect = 0.000e+0 Identity = 795/1720 (46.22%), Postives = 1088/1720 (63.26%), Query Frame = 3
Query: 438 LLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKH--LTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSEN----FPI-KMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGS-FKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFEN-----------------EIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMI 5522
LLH+KSNK LTVNKRLPALLEKNAMRV+LD GNEGSW +QPF+K A GDNV+VGDKV LNPVNAGQPLH S+YDL DH GCKE+N+V+CNTSW+INLF+ + ++ +DVLKGGDVVRLFHAEQEKFLTCDEYK +VFLRTT R +ATSATSS ALWE+EVV+ D CRGGAG W+SL+RFKHLATG YLAAE+D R R G+ + LV + ND+ S+FE+DPT ++D +VP +S+VR+++ CT W+ ST++PID +E++PI +G KEDKEAFAIV V E+RDLDFAND S +LS V +++ ++ ND+ + LL V+FF+ V ++G LD+ +K+ +R+RQKL+REQNILKQIF IL++P ++ P+ ++++L DQK+ ++ + +LCYR+L+ SQ+DYRKNQ +IAKQ MMQ QIGY ILAEDTITALLHNNRKLLEKHIT +E+ TF+NL+R ++ FL +LSDLC+SNNVAIP+TQELICKC+ NQDIL+KT LL + +++ K K++++L A + DE++LTYY YQL L++ MCLDRQYLAI+ +S +L + LI C+ ++ P +LRASFCRLM+H HVDRDPQE+VTPV++ARLWT+IP + I YDS ++ ++ K F M+F+EEYLNN+ N+ + F N E+NKLT E+V+LA+HLIYFGFY+F + LRL +TLL I+D P PG F++ + NK S + D +M+TK + +EILQFILNVRLD++++ LL +FK F + I++ +I +QAE +F K N +++D EGG++FLRVL++L MH+Y +VSGALQ+LFRHF+QRQEVL TFKQVQLL+S DVENY+ IKA+LD LR LVEKSELWV K SS ++ + +S++ K T + +E E NY +KEILERL +C S K +QRLLKNMGAH V+++LLQ+ +D KND+KMQEI+ H+FLQ+FC GN+ NQ +LHKN +LFL PG L EAET+ I+ +N +LC+ + E V+QH++ C+ THG V +L FL TIIKA+ +Y++KCQDM+++E YHI LV+LLA EGKNVY+EIKC SLL +ED+ +V H C VK AY+ F+ HCY+DTEVE+K+I++ N +W+LF +D+A R D LE+ + + ++ I FF+SPFSE +T ++ T VI LLQ+ RL C WL K + ++T L + K++ I++P E+E I + L + + S N + +++ID L + I LE +L+PL+ AE+SVLV V H+PELLF T+ R +CESG FIS LI+HT+ L+ S EEKLCIKVL+TL+ M+ ++FD+K LR+ LL +N L N ++E D + V +Q LD +G + L DL++ + N+++F+E I+ I LLEGGNT +Q SFY+ + D S+KFF+ + EAQ +IK+ +
Sbjct: 31 LLHMKSNKYLTVNKRLPALLEKNAMRVTLDGTGNEGSWLFIQPFWKLRANGDNVLVGDKVILNPVNAGQPLHASNYDLNDHSGCKEVNSVNCNTSWKINLFMMFSDHREDVLKGGDVVRLFHAEQEKFLTCDEYKSKLHVFLRTTLRQSATSATSSNALWEIEVVHHDPCRGGAGHWNSLYRFKHLATGNYLAAEMDGR------RISKRSQGERIKYKLVVLSDGNDIASLFELDPTTLQKTDSFVP-NSYVRLRHLCTNTWIQSTNVPIDIDEERPIRLMLGTCPTKEDKEAFAIVSVPVMEIRDLDFANDASAMLSTVVEQLTRGFISPNDRFAI-KLLEDVVFFVTDVANAGQSVLDVVMKKPNRERQKLMREQNILKQIFGILKTPSAKREGGEAPLFRLEELGDQKNSHYQYMFQLCYRVLRHSQEDYRKNQ-HIAKQFGMMQGQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRTNREP---FLDYLSDLCVSNNVAIPVTQELICKCVLDPKNQDILIKTVW-----------------------LLWTDKIKE-----------------------KHEKSIRQLAQEARQGNTHDENVLTYY-YQLKLFARMCLDRQYLAIDEISKQLDVELIFLCMMDEMLPFDLRASFCRLMLHAHVDRDPQELVTPVKFARLWTEIPTSISI-KYDS--NMDDSRDNKKNRFANTMVFMEEYLNNVLNDEMPFHNVEKNKLTYEVVSLARHLIYFGFYSFFELLRLTRTLLGIIDSRPNP------------GHPGPIFQDDGPAQRGNKDSLEKMDLT---VMDTKSKILEILQFILNVRLDYRLSFLLSVFKKEFVDVYPMADADATTNMEQAATINLQRIGEQAEAMFGIKGNSI-LEVDDEGGRMFLRVLIHLTMHEYAPLVSGALQLLFRHFSQRQEVLHTFKQVQLLISAQDVENYKLIKANLDRLRTLVEKSELWVEKK--SSAGGDGKKDKKDKKEISEVSDK----PTPTKEKLEKGNE-------------NYQMVKEILERLHRMCSSG---VWKKQQRLLKNMGAHKVMLDLLQVSYD-KNDVKMQEIIKYTHLFLQKFCMGNQENQALLHKNLNLFLNPGQLL----------EAETVQHIFSNNYQLCSEISESVLQHFIHCLATHGRHVQYLNFLHTIIKAEGKYVKKCQDMIMTE---------------------------------------YHISLVELLAACAEGKNVYTEIKCTSLLPLEDVVKVVTHVDCITEVKTAYVNFVNHCYVDTEVEMKEIYTSNH-IWNLFEDFTVDMA-RVCNKRESRLADPVLEKYIVNVVLDTINAFFSSPFSENSTSLQTHHTIVIKLLQSCIRLLDCQWLQQQHKVQVDACIRT-LSMTKSRSIVVPPEVESHIKQMSASSYNTLSRTNP------QYKSVSRSSRPIPSSNPWDYKNIIDKLQEVINTLEDRLKPLVNAELSVLVDVLHQPELLFPEGTDVRRRCESGSFIS-LIQHTKALM-STEEKLCIKVLKTLQEMLIRTLDFDEKGLSLRKVLL---------QNYLYQNRKGEQER-------------DWATVVAVQCRLDREGGTKLFTDLVM-STKNDKIFQESIQLAICLLEGGNTEIQNSFYKLMMGDNKSEKFFKVLHDRMKEAQTDIKATV 1566 HSP 2 Score: 679.478 bits (1752), Expect = 0.000e+0 Identity = 388/762 (50.92%), Postives = 526/762 (69.03%), Query Frame = 3
Query: 5799 EENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSD--INSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEK--ERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSH-KEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLL 8069
E + +V I++PI RFLQLLCENH +LQ+ LR Q NKT+YNLVCETLQFLD +CGST+GGLGLLGLYINE NV LI Q L TLTEYCQGPC ENQ I HESNGIDII ALILNDI+PL +M++VL+LKDNASKLLLA++ESRHD+ENAERIL NL P++LV+V K A+ +D + +V SP EVGHNIYILA QL++H + L LL+P + + ++ + + ++IVR DRSME+IVFP+ ICE++T+E++ +V TE DEQGSKV +F +T+++ EM+WQK LR +L+W S M LW I+F + +N+++ ++YP+ + ++++ + W+ LS++ R + L ALI++ ++L I L+ +G LNL+N ++F++S GN G + ++ EFL H + ++ ++LGL +H LFYS+ L DLI REETL NVI+SVT+N RS++LT +L +IL Y F+I G L ++DF ME DPE ER CDTL MC+ T L GLRNGGG+GD+LRKPS +E F RV++DL FYFIV +I+LNLIFGVIIDTFA LR KQ+K+EIL+ TCFIC L R FDNKTV+FEEH EHN+W+YLYFIVL++ K+ T++TGPESYV+ M+K NLDWFP+ +AMSL + + EQN+++ LQ +L T ++++ L+ QLTELK QMTEQRK++QR +
Sbjct: 1579 EGEMEMGPAVTIMKPILRFLQLLCENHNLDLQNFLRSQN-NKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEFNVHLIIQTLETLTEYCQGPCQENQTCIVTHESNGIDIITALILNDISPLCHYQMEMVLQLKDNASKLLLALMESRHDNENAERILFNLRPQELVEVIKKAYNQDIECEEMEV-----------------SPLEVGHNIYILAQQLARHNKVLQNLLKPPKKNVEGEEGI-------SSMQIVREDRSMEQIVFPVHPICEFLTKESRLRVFNTTEQDEQGSKVTHYFEQTSFLHGEMEWQKKLRM-PMLYWFSRRMSLWGTISFRLAVYINLIIALFYPYAIDD----SLLLMLFWILTGLSVMGVFSQRYGLQPL--TAALILRSIYHLGIGNTLILLGSLNLINKVVFVVSFVGNNGTFIMGYKAMVMDVEFLYHLAYVLTSILGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLCLKEDFIMEV--------------DPESNLERACDTLLMCIVTVLNHGLRNGGGVGDVLRKPSKDQEPLFPARVVYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFIC-LERDKFDNKTVSFEEHINMEHNIWNYLYFIVLLREKNKTDYTGPESYVAHMMKNNNLDWFPRMQAMSLVVTDSDGEQNEMRILQDKLGSTMKVVTTLTAQLTELKEQMTEQRKRRQRMGFV 2293
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Medaka
Match: ENSORLT00000014249.2 (pep primary_assembly:ASM223467v1:6:21638618:21648331:1 gene:ENSORLG00000026619.1 transcript:ENSORLT00000014249.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 597.43 bits (1539), Expect = 0.000e+0 Identity = 317/596 (53.19%), Postives = 413/596 (69.30%), Query Frame = 3
Query: 510 MRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIK--HLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPL---SENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYR 2282
MRVSLD GNEGSWF +QPF+K + GDNVVVGDKV L PVNAGQPLH S+ +LLD++GCKE+NAV+CNTSW++ LF+++ + +DVLKGGDVVRLFHAEQEKFLTCD YK+ Q+VFLRTT R +ATSATSSKALWEVEVV+ D CRGGAG W+SLFRFKHLATG YLAAE+ TP ++ + + LVS+P S D+ S+FE+DPT R+D VPR+S+VR+++ CT WV ST+ PID EE++P+M K+G KEDKEAFAIV V EVRDLDFAND SKVL +KI+ +L N+++ V LL ++FF+C V ++G D L + +R+RQKL+REQNIL QIF ILE+P E +K++ L DQ++ + I +LCYR+L+ SQQDYRKNQEYIAK +MQ QIGY ILAEDTITALLHNNRKLLE+HIT EI TF+N +R+ ++ R+L +LSDLC+SN +AIP+TQELICK + + +N +IL +T+ + E+++ + + ++ K P K+++ L A N K D +TYYR
Sbjct: 1 MRVSLDPAGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNAGQPLHASNIELLDNLGCKEVNAVNCNTSWKVTLFMKFSDYREDVLKGGDVVRLFHAEQEKFLTCDGYKRQQHVFLRTTLRQSATSATSSKALWEVEVVHYDPCRGGAGHWNSLFRFKHLATGNYLAAEVCL--TPRDASFFYHQAAERIAYTLVSLPGS-DIASLFELDPTTLQRTDCPVPRNSYVRLRHLCTNTWVTSTNFPIDAEEERPVMLKIGTCRSKEDKEAFAIVSVPLSEVRDLDFANDASKVLEATVKKIQNDNLPQNERRFVTKLLEDLVFFVCVVPNNGQDVLSVATSSPNRERQKLMREQNILAQIFGILEAPFIDNGEGAMLKLEQLGDQRYAHIKYILKLCYRVLRHSQQDYRKNQEYIAKNFSIMQSQIGYEILAEDTITALLHNNRKLLEQHITAREIETFVNQLRRNREP--RYLDYLSDLCVSNKMAIPVTQELICKFMLNPSNAEILFQTKYLSTLGSS------------EEEEEVWLYWIDSNKEPY--------------------GKSIRHLAQDAKSNHKKDVENITYYR 559
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Planmine SMEST
Match: SMESG000061586.1 (SMESG000061586.1) HSP 1 Score: 5282.61 bits (13702), Expect = 0.000e+0 Identity = 2676/2676 (100.00%), Postives = 2676/2676 (100.00%), Query Frame = 3
Query: 75 MNNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
MNNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLRTTGRTTATSATSSKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRIVEIEYEVEPEYDDGFEDDDLLTVNGVEKTKHPETIFETEEEEEIIVTWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINYLSSELSIYLILKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKESSNSLIINKISSKTSDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAKVSTTVVSKRSVDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSGGLGLLGLYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGIDIIIALILNDINPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ
Sbjct: 1 MNNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLRTTGRTTATSATSSKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRIVEIEYEVEPEYDDGFEDDDLLTVNGVEKTKHPETIFETEEEEEIIVTWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINYLSSELSIYLILKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKESSNSLIINKISSKTSDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAKVSTTVVSKRSVDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSGGLGLLGLYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGIDIIIALILNDINPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 2676
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Planmine SMEST
Match: SMESG000061586.1 (SMESG000061586.1) HSP 1 Score: 5252.95 bits (13625), Expect = 0.000e+0 Identity = 2665/2676 (99.59%), Postives = 2665/2676 (99.59%), Query Frame = 3
Query: 75 MNNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
MNNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLRTTGRTTATSATSSKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRIVEIEYEVEPEYDDGFEDDDLLTVNGVEKTKHPETIFETEEEEEIIVTWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINYLSSELSIYLILKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKESSNSLIINKISSKTSDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPG LHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAKVSTTVVSKRSVDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSGGLGLLGLYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGIDIIIALILNDINPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ
Sbjct: 1 MNNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLRTTGRTTATSATSSKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRIVEIEYEVEPEYDDGFEDDDLLTVNGVEKTKHPETIFETEEEEEIIVTWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINYLSSELSIYLILKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKESSNSLIINKISSKTSDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPG-----------LHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAKVSTTVVSKRSVDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSGGLGLLGLYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGIDIIIALILNDINPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 2665
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Planmine SMEST
Match: SMESG000061586.1 (SMESG000061586.1) HSP 1 Score: 5220.98 bits (13542), Expect = 0.000e+0 Identity = 2649/2652 (99.89%), Postives = 2649/2652 (99.89%), Query Frame = 3
Query: 156 MSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLXXXXXXXXXXXXXXKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRXXXXXXXXXXXXXXGFEDDDLLTVNGVEKTKHPXXXXXXXXXXXXXXXWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFEN---EIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAXXXXXXXXXXXXDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 8102
MSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLRTTGRTTATSATSSKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRIVEIEYEVEPEYDDGFEDDDLLTVNGVEKTKHPETIFETEEEEEIIVTWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINYLSSELSIYLILKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKESSNSLIINKISSKTSDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFEN EIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAKVSTTVVSKRSVDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSGGLGLLGLYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGIDIIIALILNDINPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ
Sbjct: 1 MSTLGLVDDRCVVQPSAGDLHNPPKKFRDCHFKICPMSRFSAQKQFWNATKQGAQTDSLLINKLHSAAELEKTQNEIEHKKLVGTVVQYGTVIQLLHIKSNKLLTVNKRLPALLEKNAMRVSLDSNGNEGSWFCVQPFYKHCAMGDNVVVGDKVTLNPVNAGQPLHVSSYDLLDHVGCKEINAVSCNTSWQINLFLEYKENMDDVLKGGDVVRLFHAEQEKFLTCDEYKKDQYVFLRTTGRTTATSATSSKALWEVEVVNKDACRGGAGKWSSLFRFKHLATGQYLAAEIDKDPTPDLMRSKLRKSGDDDVFCLVSIPQSNDVTSIFEIDPTICTRSDDYVPRSSFVRMKNFCTGAWVHSTSIPIDKEEDKPIMHKVGCALLKEDKEAFAIVQVSAEEVRDLDFANDVSKVLSVVTQKIKHLTINDKKVVYNLLSCVIFFLCSVEDSGSDPLDLEVKEIDRDRQKLLREQNILKQIFKILESPLSENFPIKMDDLTDQKHVIFRNICRLCYRILKLSQQDYRKNQEYIAKQLPMMQKQIGYGILAEDTITALLHNNRKLLEKHITVSEINTFINLIRKGKDSSFRFLKHLSDLCISNNVAIPITQELICKCLFHENNQDILVKTEIYKRIVEIEYEVEPEYDDGFEDDDLLTVNGVEKTKHPETIFETEEEEEIIVTWDNGKQSKNLQELVNAANGNSKDDESILTYYRYQLNLYSNMCLDRQYLAINYLSSELSIYLILKCIANDSFPQNLRASFCRLMIHLHVDRDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLRLVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKESSNSLIINKISSKTSDADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENGNNEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVSTNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQTCHKNYVTIKEILERLIVLCESDDPKSRKHEQRLLKNMGAHTVIIELLQIPFDKKNDIKMQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAETMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVPFLKFLQTIIKAQDQYIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQLLPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEVEIKDIFSVNSPMWDLFNTLLLDIAKVSTTVVSKRSVDKELEECVTHTIMGVIVTFFNSPFSEQNTVIKNKQTEVIHLLQNVFRLYQCTWLTADQKNNITFSMKTVLEIIKAKGILIPFELEHQINKHMLKDQAILKHSKAWLTIKNKKDSQFTQYERPSLQNGLETRSVIDFLHDTIVALETQLQPLMQAEVSVLVCVFHRPELLFLPHTEARHKCESGGFISRLIKHTECLLTSNEEKLCIKVLQTLRMMVSMDIEFDDKANYLRQKLLVKYFGNKLSKNVLKINSSTKKEELSNPIVEEIPRSFDQLSFVDIQDYLDSQGASNLIIDLIIHHSSNERVFREIIEFGIALLEGGNTNVQKSFYERLCHDKSSDKFFQAFSSSITEAQNEIKSMIILAADGNSQNSLENVMPRRRVRDRSNIPAMLRQQLDDAAIESNQALIAVRKSLNRNSVNVDQKSENISDIVNGIDQENTNSNISNVFFKEIAEENYRLSNSVIIIEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSGGLGLLGLYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGIDIIIALILNDINPLGRTRMDLVLELKDNASKLLLAIVESRHDSENAERILINLSPKQLVDVAKLAFYEDTLLDVDDVPSESSGETGLTGRSDLASPKEVGHNIYILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFPAKENNHPNVMVSVIWLFIVLSLVATVFIRNTMSVLIFVTALIIKISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRKPSHKEKFFGFRVLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENWPATNQQ 2652
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1) HSP 1 Score: 206.838 bits (525), Expect = 9.450e-53 Identity = 191/790 (24.18%), Postives = 366/790 (46.33%), Query Frame = 3
Query: 5835 IEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHD--SENAERILINLSPKQLVDVAKLAFYEDTLLD-VDDVPSESSGETGLTGRSDLASPKEVGHNI--YILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFP-----------AKENNH-PNVMVSVI------------WLFIVLSLVATVFIRNTMSVLIFVTALII------KISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRK--PSHKEK-FFGFR--VLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENW 8084
IE + + L +C+ + LQ LR Q N S+NLV E +QFL+ + + IN+ + L++Q T+ E+ G +N + +++ ID I ++ P + ++ELK N L+++++E + ++ A + L + + V A+ + D + D+ S+ E G + LA ++ N+ ++ L K + L ++ P Q +A ++Y K++ IE+++ D ++++ F I I EE K VK + +K+ F + + ++++QK + + + +LW+ ++++N++++ + P +K NN P+ + + W+F A + N + + T + +I +Y + L L+ + I G+ G +S I+S+ + + + ++ G P F++ L++++ + L VI +VTQN +SL+ ILG+++ Y + I G FF+ F + EK YCD+L C + + GL +GD+ P EK FF F V++ LSF+ ++ I LN+IFG+I+DTF+ LR K + +R+TCFIC+ N F++ FE H EHNMW Y++F + ++ ++T + +V+ ++K + D+FP RA+ L A + + S S++ D+++ N+S T + +Q +E ++K+ LLR + W
Sbjct: 1426 IELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYAN-----------INKDTIDLVSQVFSTINEFVAG---NQENRVTVYDNKIIDYINYILRGGNYP--DCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHEVKDEIKDLKSKLC-EVGFSYYFILARLYDLDPNLGKKVIGDSLIKTTKSL--IITPNQQ-----KAFKFYKKNSVSIELLKGDY-LQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMF------AFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDII---QQGDEGCKMRSHL-ISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF------------------NTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDED-------STDSKI---DELLKNVS---TLINHQKSEDSERKRFEELLRQKRW 2143 HSP 2 Score: 76.2554 bits (186), Expect = 3.775e-13 Identity = 157/723 (21.72%), Postives = 297/723 (41.08%), Query Frame = 3
Query: 2253 DDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXK---CIANDSFPQNLRASFCRLMIHLHVD-RDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLR-LVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXD-----ADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVST--NDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQT--CHKNYVTIKEILERLIVLCESDDPKSRKH--EQRLLKNMGAHTVIIELLQIPFDKKNDIK---MQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAE---TMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVP-FLKFLQTIIKAQDQ--YIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQL---LPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEV 4337
DDE + + QL+L++ +C R I ++ +LS + + ++ P ++RA +C ++I L VD + +V + ++ + K D + ++DQ K+ V + F + ++ +L+ N ++ S E N L +++ L L+ FG+Y D +R L+ L+ ++D S DL ++ G KE S + D + + I+N K +E+LQ ILN F+ L F A F K C++ E + +K+ P+ ++ AL + FN ++ ++ +L++ EN Q+K D T L+ + N+L+ + S ++D + + + + + E A ++ L + ++ + ++ I LI C H QR+L + V++E+L + D + K +++L A L+ Q + +N D+ L L E+E T+ ++ +N LC + + + V H + P FL L I+K + +++ Q +V+ ++ L ME++ A L L +QY I L++LL+ EG+N Y E C ++LSVEDI N++ HP +K +L +L Y+ +
Sbjct: 201 DDEKV-QFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTK-DQNKTTTSDQY-AAKDLVTI-FPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSR--------DLPFPPERQG--KELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILN----FESNARLAGFMAKF-------KECERNEGLLKKKN---------------------------PSSLACAL---YEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVK-----------LVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYI---------LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPI 846
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Planmine SMEST
Match: SMESG000023213.1 (SMESG000023213.1) HSP 1 Score: 206.838 bits (525), Expect = 1.005e-52 Identity = 191/790 (24.18%), Postives = 366/790 (46.33%), Query Frame = 3
Query: 5835 IEPIFRFLQLLCENHYRELQDLLRHQACNKTSYNLVCETLQFLDCICGSTSXXXXXXXXYINEHNVGLINQNLRTLTEYCQGPCHENQNAIAQHESNGXXXXXXXXXXXXXPLGRTRMDLVLELKDNASKLLLAIVESRHD--SENAERILINLSPKQLVDVAKLAFYEDTLLD-VDDVPSESSGETGLTGRSDLASPKEVGHNI--YILAHQLSKHKRELAQLLQPGQNDSYTDQALEYYAKHTAQIEIVRSDRSMERIVFPIPEICEYITEETKFKVKTQTELDEQGSKVPGFFSETNYMFQEMQWQKSLRAKSLLFWMSNHMVLWSDINFFFTLVMNILLIIWYPFP-----------AKENNH-PNVMVSVI------------WLFIVLSLVATVFIRNTMSVLIFVTALII------KISFYLDIAPFLLFMGCLNLMNNIIFIISLWGNRGIAKKSWSDINSEFLIHSSSMICNVLGLLVHPLFYSVTLLDLIRREETLLNVIRSVTQNYRSLVLTTILGVILSYFFTIFGHLFFQDDFQMEPEFLDIISGKIGSDGDPEKERYCDTLGMCLTTTLYQGLRNGGGIGDILRK--PSHKEK-FFGFR--VLHDLSFYFIVNVIILNLIFGVIIDTFASLRQNKQEKDEILRNTCFICALNRSAFDNKTVTFEEHFRREHNMWHYLYFIVLIKVKDPTEFTGPESYVSEMIKAKNLDWFPKKRAMSLAADEHEVEQNDLKSLQSRLEFTDQIISNLSDQLTELKNQMTEQRKQKQRYSLLRPENW 8084
IE + + L +C+ + LQ LR Q N S+NLV E +QFL+ + + IN+ + L++Q T+ E+ G +N + +++ ID I ++ P + ++ELK N L+++++E + ++ A + L + + V A+ + D + D+ S+ E G + LA ++ N+ ++ L K + L ++ P Q +A ++Y K++ IE+++ D ++++ F I I EE K VK + +K+ F + + ++++QK + + + +LW+ ++++N++++ + P +K NN P+ + + W+F A + N + + T + +I +Y + L L+ + I G+ G +S I+S+ + + + ++ G P F++ L++++ + L VI +VTQN +SL+ ILG+++ Y + I G FF+ F + EK YCD+L C + + GL +GD+ P EK FF F V++ LSF+ ++ I LN+IFG+I+DTF+ LR K + +R+TCFIC+ N F++ FE H EHNMW Y++F + ++ ++T + +V+ ++K + D+FP RA+ L A + + S S++ D+++ N+S T + +Q +E ++K+ LLR + W
Sbjct: 1435 IELVLKLLARICDGQHPGLQTYLREQPDNVKSFNLVAEVVQFLNVVYAN-----------INKDTIDLVSQVFSTINEFVAG---NQENRVTVYDNKIIDYINYILRGGNYP--DCSIHQMIELKQNIGNLVISMIEENNPDATQIANEVKDTLDKEAIYRVMTEAYEMHEVKDEIKDLKSKLC-EVGFSYYFILARLYDLDPNLGKKVIGDSLIKTTKSL--IITPNQQ-----KAFKFYKKNSVSIELLKGDY-LQKVHFRIRN-KNIIREEVKEVVKWNVDRSSPSNKIRDFMDWSKSILNDIRYQKKAMNNPIAKFFTGGWLLWNYAITILSVILNLMMLTVFKAPKDGSFDENFNISKFNNSLPDFFRNPVPDWKPRFENLKSWMF------AFGLVHNVLCGFLLFTYFLADHPSPPRIQYYFILIKRRLKQNELDPADEDII---QQGDEGCKMRSHL-ISSKTFYYFAILGFSLAGQWYSPYFFAFHLVNIVHNNQLLQGVISAVTQNGKSLIWVAILGMVVIYLYAIIGFAFFRSGF------------------NTEKNLYCDSLWHCFVSVMRFGL-----VGDLFENLLPHDSEKSFFTFSMLVIYHLSFFILITTIGLNIIFGIIVDTFSELRDLKWTAESDMRDTCFICSRNSYDFEHHGQGFEYHVLNEHNMWSYIFFFIHLQDTKANDYTSLDMFVATLLKEQKFDFFPLNRALCLTAKDED-------STDSKI---DELLKNVS---TLINHQKSEDSERKRFEELLRQKRW 2152 HSP 2 Score: 76.2554 bits (186), Expect = 3.873e-13 Identity = 157/723 (21.72%), Postives = 297/723 (41.08%), Query Frame = 3
Query: 2253 DDESILTYYRYQLNLYSNMCLDRQYLAINXXXXXXXXXXXXK---CIANDSFPQNLRASFCRLMIHLHVD-RDPQEIVTPVRYARLWTDIPKKMDIDNYDSADQENEQKEEVKLNFGPVMLFVEEYLNNIANNNLMFSNQEQNKLTLEIVNLAKHLIYFGFYTFRDHLR-LVKTLLRILDFSAIPMKVTQLDLDIESQKPGSFKEXXXXXXXXXXXXXXXD-----ADNTLIMNTKLRNIEILQFILNVRLDFQITCLLCIFKAHFENEIDISKICQQAEDIFSEKDNVYEIDLDGEGGQVFLRVLLNLIMHKYPAVVSGALQMLFRHFNQRQEVLQTFKQVQLLVS--TNDVENYRQIKADLDTLRLLVEKSELWVYKNKLSSDKKRKDVSIQEDQVLSDLHAKYKNSVTASTIGVESAIELDLGPKIDQT--CHKNYVTIKEILERLIVLCESDDPKSRKH--EQRLLKNMGAHTVIIELLQIPFDKKNDIK---MQEILALAHVFLQRFCNGNESNQFVLHKNNDLFLTPGHLFCTEDFVYCLHEAE---TMSAIYKDNIKLCNSVPEKVVQHYVRCIETHGHQVP-FLKFLQTIIKAQDQ--YIRKCQDMVISELISVGDEVLVFYNDDLKFVHLINMMESQRAQL---LPNGPLQYHIELVKLLAMVTEGKNVYSEIKCHSLLSVEDICNIVCHPSCTVPVKEAYLMFLCHCYIDTEV 4337
DDE + + QL+L++ +C R I ++ +LS + + ++ P ++RA +C ++I L VD + +V + ++ + K D + ++DQ K+ V + F + ++ +L+ N ++ S E N L +++ L L+ FG+Y D +R L+ L+ ++D S DL ++ G KE S + D + + I+N K +E+LQ ILN F+ L F A F K C++ E + +K+ P+ ++ AL + FN ++ ++ +L++ EN Q+K D T L+ + N+L+ + S ++D + + + + + E A ++ L + ++ + ++ I LI C H QR+L + V++E+L + D + K +++L A L+ Q + +N D+ L L E+E T+ ++ +N LC + + + V H + P FL L I+K + +++ Q +V+ ++ L ME++ A L L +QY I L++LL+ EG+N Y E C ++LSVEDI N++ HP +K +L +L Y+ +
Sbjct: 210 DDEKV-QFLLAQLDLFNAICYGRNEYCIRLITKDLSYLSWEEGFLSLQSEILPDDVRAKYCEMIIGLFVDVGNNYSVVDHPERSFVYEYVGTK-DQNKTTTSDQY-AAKDLVTI-FPALRDWIAAFLDE--NTYMIASKIEHNMLIEQVLRLLNFLVKFGYYGDVDDVRSLLDKLIGLIDGSR--------DLPFPPERQG--KELSKEKKKIVQKYQQGDRYLQSKETSAIVNAKYAALEVLQMILN----FESNARLAGFMAKF-------KECERNEGLLKKKN---------------------------PSSLACAL---YEGFNPYEKKPSAVRKQKLMIKELREMFENTTQVKIDQMTNILINLAHYKYAKMNQLALEVLNLLYSGKQDTFQAATESLVLMTTDSCCVHREVAKQVPLLRMMAKSKWSDEQVNRMENIFSELIEFCHLPKAPEEPHPMNQRILDSDNVIGVVMEILSVETDSQLTEKYSQTEKVLRKALQLLKAMALQYPDVQNQIFENLDMLLRVK-----------LVESELAITLKEVFVNNQNLCLKILPRQIHKIVSLAAEHQQKAPEFLDLLCAIVKVEGLGLALKRNQTLVMKYIMQSYSSAAYI---------LEQPMETREAVLKEELGEDHVQYLISLIELLSTCAEGENRYIESLCQTILSVEDILNVLNHPEIANHLKRPFLKYLMFAYLKKPI 855 The following BLAST results are available for this feature:
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Inositol 1,4,5-trisphosphate receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014577 ID=SMED30014577|Name=Inositol 1,4,5-trisphosphate receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=8263bpback to top protein sequence of SMED30014577-orf-1 >SMED30014577-orf-1 ID=SMED30014577-orf-1|Name=SMED30014577-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2677bp MNNIESKSFLHIGDIISLYAEGNVSGFMSTLGLVDDRCVVQPSAGDLHNPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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