Angiotensin-converting enzyme

Overview
NameAngiotensin-converting enzyme
Smed IDSMED30014565
Length (bp)2360
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Angiotensin-converting enzyme (SMED30014565) t-SNE clustered cells

Violin plots show distribution of expression levels for Angiotensin-converting enzyme (SMED30014565) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Angiotensin-converting enzyme (SMED30014565) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Angiotensin-converting enzyme (SMED30014565) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014565

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 15

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30014565h1SMcG0014372 Contig4969GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014565h1SMcG0014371 Contig48165newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014565h1SMcG0014371 Contig48165uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014565h1SMcG0014371 Contig4969GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
protonephridiaSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014565h1SMcG0017955 Contig4969GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Category 3 cellSMED30014565h1SMcG0014372 dd_Smed_v6_3745_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014565h1SMcG0014372 dd_Smed_v4_3745_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Human
Match: ACE (angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707])

HSP 1 Score: 392.889 bits (1008), Expect = 4.172e-125
Identity = 222/566 (39.22%), Postives = 331/566 (58.48%), Query Frame = 3 
Query:  354 NRYANLNYRYGSNINKTNLELL--KKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG-----EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            N YA  N+ Y +NI     ++L  K  QI    L    Q  A+KF   +  +  +++I+ K+    R+    +    +E  +KI            +C P G     EP + ++    + Y+ L   W  WR+  G  I   + K VEL N  AR NG+ D A       +E  + ++ + +L++ + PLY  LH++VR  L ++Y  +  +  GPIPAH+ GN+W+Q W+NI+++V     +   +    +A  K +  + R+MF+ A++F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  +L D    HHEMGHI+YFM Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + LL     S E DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV R++ DFD GAK+HI  SVPYIRYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG +L   +K G    W E M+++TG   + + ++L +F+PL  WL+ +N     ++GW
Sbjct:   91 NEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQ--ARKFDVNQLQNTTIKRIIKKVQDLERAA---LPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD-AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLK-QGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Human
Match: AC113554.1 (novel protein)

HSP 1 Score: 392.889 bits (1008), Expect = 5.721e-125
Identity = 222/566 (39.22%), Postives = 331/566 (58.48%), Query Frame = 3 
Query:  354 NRYANLNYRYGSNINKTNLELL--KKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG-----EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            N YA  N+ Y +NI     ++L  K  QI    L    Q  A+KF   +  +  +++I+ K+    R+    +    +E  +KI            +C P G     EP + ++    + Y+ L   W  WR+  G  I   + K VEL N  AR NG+ D A       +E  + ++ + +L++ + PLY  LH++VR  L ++Y  +  +  GPIPAH+ GN+W+Q W+NI+++V     +   +    +A  K +  + R+MF+ A++F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  +L D    HHEMGHI+YFM Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + LL     S E DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV R++ DFD GAK+HI  SVPYIRYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG +L   +K G    W E M+++TG   + + ++L +F+PL  WL+ +N     ++GW
Sbjct:   91 NEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQ--ARKFDVNQLQNTTIKRIIKKVQDLERAA---LPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD-AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLK-QGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Human
Match: ACE (angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707])

HSP 1 Score: 396.356 bits (1017), Expect = 1.449e-121
Identity = 227/597 (38.02%), Postives = 346/597 (57.96%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELL--KKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG-----EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++YPE  +  ++E  A  ++ + +  +    N YA  N+ Y +NI     ++L  K  QI    L    Q  A+KF   +  +  +++I+ K+    R+    +    +E  +KI            +C P G     EP + ++    + Y+ L   W  WR+  G  I   + K VEL N  AR NG+ D A       +E  + ++ + +L++ + PLY  LH++VR  L ++Y  +  +  GPIPAH+ GN+W+Q W+NI+++V     +   +    +A  K +  + R+MF+ A++F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  +L D    HHEMGHI+YFM Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + LL     S E DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV R++ DFD GAK+HI  SVPYIRYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG +L   +K G    W E M+++TG   + + ++L +F+PL  WL+ +N     ++GW
Sbjct:  634 DNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQ--ARKFDVNQLQNTTIKRIIKKVQDLERAA---LPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD-AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLK-QGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221

HSP 2 Score: 382.489 bits (981), Expect = 1.870e-116
Identity = 211/565 (37.35%), Postives = 331/565 (58.58%), Query Frame = 3 
Query:  372 NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQ---WKRFSSPNVRKILDKLSKTVRSQDENISRNLV--EVKSKIEYIYNNGKPCFGICLP-------AGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ + +NI   N    ++  ++  +   +   KAK+     W+ F+ P +R+I+  + +T+ S +  +++      + S +  IY+  K    +CLP       + +P + ++    + Y  L   W  W N  G  ++ L+     L N   +++GF+D  ++     +    F++ +  LY+ + PLY  LH+FVR  L + Y  ++ +  GPIPAH+ G++W+Q W NI+++V        + +    ++   +  +   MF +AEEF+ S+ L  M  EFWE S++E+   GR + CH SA DF N  D+RI  CT+  ++  +T+HHEMGHI+Y++ Y  LP   R  AN GFHEAIGD +AL+V TPEHLHKIGLL  +    E DI YL+  ALEK+AFLPF   +D + W V++G  P S+ N  WW L  KYQGI PPV R+E  FDAGAK+H+    PYIRYF+SF++QFQF+E++C  +GY+GPLH+CD Y+S KAG KL ++L+ G    W+E +K + G   + +  LLK+F+P+  WL+ +N+     +GW
Sbjct:   68 SWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAV-RTLGSANLPLAKRQQYNALLSNMSRIYSTAK----VCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY-WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPD---KPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Human
Match: ACE (angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707])

HSP 1 Score: 396.356 bits (1017), Expect = 3.870e-121
Identity = 227/597 (38.02%), Postives = 346/597 (57.96%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELL--KKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG-----EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++YPE  +  ++E  A  ++ + +  +    N YA  N+ Y +NI     ++L  K  QI    L    Q  A+KF   +  +  +++I+ K+    R+    +    +E  +KI            +C P G     EP + ++    + Y+ L   W  WR+  G  I   + K VEL N  AR NG+ D A       +E  + ++ + +L++ + PLY  LH++VR  L ++Y  +  +  GPIPAH+ GN+W+Q W+NI+++V     +   +    +A  K +  + R+MF+ A++F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  +L D    HHEMGHI+YFM Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + LL     S E DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV R++ DFD GAK+HI  SVPYIRYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG +L   +K G    W E M+++TG   + + ++L +F+PL  WL+ +N     ++GW
Sbjct:  634 DNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQ--ARKFDVNQLQNTTIKRIIKKVQDLERAA---LPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD-AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLK-QGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221

HSP 2 Score: 382.489 bits (981), Expect = 5.693e-116
Identity = 211/565 (37.35%), Postives = 331/565 (58.58%), Query Frame = 3 
Query:  372 NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQ---WKRFSSPNVRKILDKLSKTVRSQDENISRNLV--EVKSKIEYIYNNGKPCFGICLP-------AGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ + +NI   N    ++  ++  +   +   KAK+     W+ F+ P +R+I+  + +T+ S +  +++      + S +  IY+  K    +CLP       + +P + ++    + Y  L   W  W N  G  ++ L+     L N   +++GF+D  ++     +    F++ +  LY+ + PLY  LH+FVR  L + Y  ++ +  GPIPAH+ G++W+Q W NI+++V        + +    ++   +  +   MF +AEEF+ S+ L  M  EFWE S++E+   GR + CH SA DF N  D+RI  CT+  ++  +T+HHEMGHI+Y++ Y  LP   R  AN GFHEAIGD +AL+V TPEHLHKIGLL  +    E DI YL+  ALEK+AFLPF   +D + W V++G  P S+ N  WW L  KYQGI PPV R+E  FDAGAK+H+    PYIRYF+SF++QFQF+E++C  +GY+GPLH+CD Y+S KAG KL ++L+ G    W+E +K + G   + +  LLK+F+P+  WL+ +N+     +GW
Sbjct:   68 SWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAV-RTLGSANLPLAKRQQYNALLSNMSRIYSTAK----VCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY-WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPD---KPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Human
Match: ACE (angiotensin I converting enzyme [Source:HGNC Symbol;Acc:HGNC:2707])

HSP 1 Score: 341.273 bits (874), Expect = 8.018e-106
Identity = 195/566 (34.45%), Postives = 296/566 (52.30%), Query Frame = 3 
Query:  354 NRYANLNYRYGSNINKTNLELL--KKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG-----EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            N YA  N+ Y +NI     ++L  K  QI    L    Q  A+KF   +  +  +++I+ K+    R+    +    +E  +KI            +C P G     EP + ++    + Y+ L   W  WR+  G  I   + K VEL N  AR NG+ D A       +E  + ++ + +L++ + PLY  LH++VR  L ++Y  +  +  GPIPAH+ GN+W+Q W+NI+++V     +   +    +A  K +  + R+MF+ A++F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  +L D    HHEMGHI+YFM Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + LL     S E DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV R++ DFD GAK+HI  SVPY                                         +   +K G    W E M+++TG   + + ++L +F+PL  WL+ +N     ++GW
Sbjct:   91 NEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQ--ARKFDVNQLQNTTIKRIIKKVQDLERAA---LPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD-AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLK-QGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPY-----------------------------------------IRTAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 606
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Celegans
Match: acn-1 (Inactive angiotensin-converting enzyme-related protein [Source:UniProtKB/Swiss-Prot;Acc:Q18581])

HSP 1 Score: 167.933 bits (424), Expect = 9.025e-43
Identity = 149/615 (24.23%), Postives = 271/615 (44.07%), Query Frame = 3 
Query:  294 NENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLS-------KTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDL---FKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFS----------DLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY--PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLS--------VRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCH-GSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIE------YLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIA-FSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +E   +SWL       I+     A   +RY ++ + +    L + + +      S  ++AK+F     +   V + L  +S          R  D + ++  +   SK   I +   P      P      ID+   F+ EKD  +L   WV++     A+ +  +   + + N GA+ NGF+          D++S +   +F+     + + ++Y  I P Y+ LH+++R  L   Y  P    K+GPIPAH+FG++    W+  +E  K          F E++      LS         +KMF  A  ++ S G   +   +W  S+  ++  + + CH  +A D     D+R+  C +    DF   H  +    Y   Y      +R  A+    +AI +  A     P +L+   L+P    S+  DI+       L   +LE    LPF +  D++ + +++GT+P +KLN+ WW++  KY+G++ P   +  + DA     ++    P  R  IS++++FQ  +++C     +G +       S     KL E +K G    W + +++++G  E+ +  LL+++EPL  WL++ N      VGW
Sbjct:  177 DEEKLRSWLAGYEAEAIKVLREVALSGWRYFNDASPSLKLALDEAENVLTMFVRSTSMQAKQFDMASVTDEKVMRQLGYVSFEGMSALAPSRFADYSQAQAALNRDSKDSTICDKDVP------PPCALQKIDMDSIFRNEKDASRLQHLWVSYVTAI-AKSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFD---LNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTKP---------FEEESETPEAMLSAFNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWSKDMICHPAAALDMRAPNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLFREQASPVITDAIANAFAHLSTNPHYLYSQKLVP----SEHLDIKDSVIINKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPATRTLISYVLKFQILKALCP----EGTILSEGCILSEDTTEKLRETMKLGSSITWLKALEMISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGW 764
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Celegans
Match: acn-1 (Inactive angiotensin-converting enzyme-related protein [Source:UniProtKB/Swiss-Prot;Acc:Q18581])

HSP 1 Score: 167.933 bits (424), Expect = 9.025e-43
Identity = 149/615 (24.23%), Postives = 271/615 (44.07%), Query Frame = 3 
Query:  294 NENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLS-------KTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDL---FKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFS----------DLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY--PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLS--------VRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCH-GSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIE------YLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIA-FSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +E   +SWL       I+     A   +RY ++ + +    L + + +      S  ++AK+F     +   V + L  +S          R  D + ++  +   SK   I +   P      P      ID+   F+ EKD  +L   WV++     A+ +  +   + + N GA+ NGF+          D++S +   +F+     + + ++Y  I P Y+ LH+++R  L   Y  P    K+GPIPAH+FG++    W+  +E  K          F E++      LS         +KMF  A  ++ S G   +   +W  S+  ++  + + CH  +A D     D+R+  C +    DF   H  +    Y   Y      +R  A+    +AI +  A     P +L+   L+P    S+  DI+       L   +LE    LPF +  D++ + +++GT+P +KLN+ WW++  KY+G++ P   +  + DA     ++    P  R  IS++++FQ  +++C     +G +       S     KL E +K G    W + +++++G  E+ +  LL+++EPL  WL++ N      VGW
Sbjct:  177 DEEKLRSWLAGYEAEAIKVLREVALSGWRYFNDASPSLKLALDEAENVLTMFVRSTSMQAKQFDMASVTDEKVMRQLGYVSFEGMSALAPSRFADYSQAQAALNRDSKDSTICDKDVP------PPCALQKIDMDSIFRNEKDASRLQHLWVSYVTAI-AKSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFD---LNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTKP---------FEEESETPEAMLSAFNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWSKDMICHPAAALDMRAPNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLFREQASPVITDAIANAFAHLSTNPHYLYSQKLVP----SEHLDIKDSVIINKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPATRTLISYVLKFQILKALCP----EGTILSEGCILSEDTTEKLRETMKLGSSITWLKALEMISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGW 764
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Fly
Match: Ance (gene:FBgn0012037 transcript:FBtr0080553)

HSP 1 Score: 355.91 bits (912), Expect = 1.548e-112
Identity = 213/592 (35.98%), Postives = 329/592 (55.57%), Query Frame = 3 
Query:  306 AKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKT-VRSQDENISRNLVEVKSKIEYIYNNGKPC----FGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK--LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMC------DLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW*ANN 2036
            AK +L  +N+   +  N      + YGSNI   N +   +      K    +     KFQW+ + S ++++    L+K    +  E+    L++  S +E  +   K C       C  A +P I ++  K +D+++L  YW  + +  G  +R+ F + VEL    A+ N F+  A   L +++E++ F++ +  ++  I PLY+++H +VR+ L K+Y      + GPIP H+ GN+W+QQW+ I +IV     S +        SA++EK   +  KMF+M ++F+ S+ L K+  +FW++S++E+   GR + CH SA DF    D RI  CT+   +   T+HHE+GHI+YF+ Y   P  YR  AN GFHEA+GD ++L+V TP+HL KIGLL +  +  E  I  L  +AL+K+ FLPFA  MD Y WS++ G +  +  N  +W L  +Y GI+PPV RSEKDFDA AKYHI+  V Y+RY +SFIIQFQFY+S C      D    + PL  CD Y S  AG     ML  G    W + ++   G + +   ++ ++FEPL VWL+ +N   +  +GW  +N
Sbjct:   25 AKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWL-DEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIV-----SPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSN 610
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Fly
Match: Ance (gene:FBgn0012037 transcript:FBtr0343667)

HSP 1 Score: 355.91 bits (912), Expect = 1.548e-112
Identity = 213/592 (35.98%), Postives = 329/592 (55.57%), Query Frame = 3 
Query:  306 AKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKT-VRSQDENISRNLVEVKSKIEYIYNNGKPC----FGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK--LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMC------DLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW*ANN 2036
            AK +L  +N+   +  N      + YGSNI   N +   +      K    +     KFQW+ + S ++++    L+K    +  E+    L++  S +E  +   K C       C  A +P I ++  K +D+++L  YW  + +  G  +R+ F + VEL    A+ N F+  A   L +++E++ F++ +  ++  I PLY+++H +VR+ L K+Y      + GPIP H+ GN+W+QQW+ I +IV     S +        SA++EK   +  KMF+M ++F+ S+ L K+  +FW++S++E+   GR + CH SA DF    D RI  CT+   +   T+HHE+GHI+YF+ Y   P  YR  AN GFHEA+GD ++L+V TP+HL KIGLL +  +  E  I  L  +AL+K+ FLPFA  MD Y WS++ G +  +  N  +W L  +Y GI+PPV RSEKDFDA AKYHI+  V Y+RY +SFIIQFQFY+S C      D    + PL  CD Y S  AG     ML  G    W + ++   G + +   ++ ++FEPL VWL+ +N   +  +GW  +N
Sbjct:   25 AKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWL-DEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIV-----SPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSN 610
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Fly
Match: Ance (gene:FBgn0012037 transcript:FBtr0080552)

HSP 1 Score: 355.91 bits (912), Expect = 1.548e-112
Identity = 213/592 (35.98%), Postives = 329/592 (55.57%), Query Frame = 3 
Query:  306 AKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKT-VRSQDENISRNLVEVKSKIEYIYNNGKPC----FGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK--LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMC------DLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW*ANN 2036
            AK +L  +N+   +  N      + YGSNI   N +   +      K    +     KFQW+ + S ++++    L+K    +  E+    L++  S +E  +   K C       C  A +P I ++  K +D+++L  YW  + +  G  +R+ F + VEL    A+ N F+  A   L +++E++ F++ +  ++  I PLY+++H +VR+ L K+Y      + GPIP H+ GN+W+QQW+ I +IV     S +        SA++EK   +  KMF+M ++F+ S+ L K+  +FW++S++E+   GR + CH SA DF    D RI  CT+   +   T+HHE+GHI+YF+ Y   P  YR  AN GFHEA+GD ++L+V TP+HL KIGLL +  +  E  I  L  +AL+K+ FLPFA  MD Y WS++ G +  +  N  +W L  +Y GI+PPV RSEKDFDA AKYHI+  V Y+RY +SFIIQFQFY+S C      D    + PL  CD Y S  AG     ML  G    W + ++   G + +   ++ ++FEPL VWL+ +N   +  +GW  +N
Sbjct:   25 AKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNFTSGAEAWL-DEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMHLLGNMWAQQWSEIADIV-----SPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSN 610
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Fly
Match: Ance-3 (gene:FBgn0032536 transcript:FBtr0343641)

HSP 1 Score: 317.39 bits (812), Expect = 1.288e-95
Identity = 171/465 (36.77%), Postives = 268/465 (57.63%), Query Frame = 3 
Query:  657 PAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGY------KGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            P + D+  K +D+D+L   WV +    G  +R+ + + +++    A  N  ++   +     +E  NF++ +  ++E I PLY+ LH++VR  L  YY P + ++  PIP+HI GN++ Q W+N+ +I+       Y        + ++  +  + + MF++AEEF+ SI +  +  EF+  S+ EQ   R + C  SA DF N  D+R+ +CT  +     ++HHEM HI+YF+ Y  LP  +RN AN  FH+A+GD I L+V TP HL  +GLL        +DI YL   A++KVAFLPFAL +D++ + V++G      +N ++W+L  KY GIKPPV RSEKDFD GAKYHI  ++PYI+YF S ++QFQ Y  +C  SG       + PLH+CD Y+   AGN L  ++ +G    W+E ++       +   +L ++F PL  WL+ +N   +  VGW
Sbjct:  335 PQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGGEYWYLA-YESGNFRQDMDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSHILGNMYGQSWSNVLDILIP-----YPGRKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQPLDRRVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPAFHQAVGDAIGLSVSTPRHLQTLGLLQRSLDESSYDINYLFTMAIDKVAFLPFALSLDNWRYDVFSGNANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFFSTVLQFQIYRGLCRESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALREYFAPLEEWLRQENLRTNEYVGW 793
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Fly
Match: Ance-3 (gene:FBgn0032536 transcript:FBtr0100327)

HSP 1 Score: 317.39 bits (812), Expect = 1.288e-95
Identity = 171/465 (36.77%), Postives = 268/465 (57.63%), Query Frame = 3 
Query:  657 PAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGY------KGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            P + D+  K +D+D+L   WV +    G  +R+ + + +++    A  N  ++   +     +E  NF++ +  ++E I PLY+ LH++VR  L  YY P + ++  PIP+HI GN++ Q W+N+ +I+       Y        + ++  +  + + MF++AEEF+ SI +  +  EF+  S+ EQ   R + C  SA DF N  D+R+ +CT  +     ++HHEM HI+YF+ Y  LP  +RN AN  FH+A+GD I L+V TP HL  +GLL        +DI YL   A++KVAFLPFAL +D++ + V++G      +N ++W+L  KY GIKPPV RSEKDFD GAKYHI  ++PYI+YF S ++QFQ Y  +C  SG       + PLH+CD Y+   AGN L  ++ +G    W+E ++       +   +L ++F PL  WL+ +N   +  VGW
Sbjct:  335 PQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGGEYWYLA-YESGNFRQDMDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSHILGNMYGQSWSNVLDILIP-----YPGRKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQPLDRRVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPAFHQAVGDAIGLSVSTPRHLQTLGLLQRSLDESSYDINYLFTMAIDKVAFLPFALSLDNWRYDVFSGNANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFFSTVLQFQIYRGLCRESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALREYFAPLEEWLRQENLRTNEYVGW 793
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Zebrafish
Match: ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:ZFIN;Acc:ZDB-GENE-030131-1826])

HSP 1 Score: 416.387 bits (1069), Expect = 1.070e-128
Identity = 239/605 (39.50%), Postives = 364/605 (60.17%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKT--------NLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVE---VKSKIEYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E YPE   + ++E  AK +L + N       N Y   ++ Y ++I +         NLE+    +I YG       L+A+K+    F   +V++IL KLS   R+     + +LVE   + + +E +Y+    C     CLP  +P +  +  + +DYD+L   W  WRN +G  IR+ + + VEL N  A+ NG +D  +F     +E   F++ +  L++ + PLY  +H++VR  L+K Y P + +  GPIPAH+ GN+W+Q W+ I ++V       Y +     A+  +  +  + ++MFE ++ F+ S+GL  M  EFW +S++E+   GR + CH SA DF N  D+RI  CT   ++D  T+HHEMGH++YF+ Y   P  +R+ AN GFHEAIGD +AL+V TP+HL  IGLL ++  + E  I +LM  AL+K+AFLPF   MD + W V++G I SS+ N+ WW+L +KYQG+ PPV R+EKDFD GAK+HI  +VPYIRYF+SF+IQFQF++ +CD +G+KGPLH CD YQS +AG  L +++K G    W E MKI+TG  ++    L+++F+PL  WL+ +N    + +GW
Sbjct:  662 EGYPEDIGKITDEMQAKQFLDEYNSTAEEVWNAYTESSWTYNTDITEAHKDNMLQKNLEMANHTKI-YG-------LEARKYDTSDFQDESVKRILSKLSDLERAALS--AEDLVEYNNLLASMETLYSVATVCKDKSNCLPL-DPDLNKIMAESRDYDELLFAWQGWRNASGREIRDSYKRYVELANSAAKSNGHTDNGAF-WRSLYETPTFEQDLEALWKDLEPLYLSVHAYVRRALYKKYGPERINLKGPIPAHLLGNMWAQTWSGIMDLVNP-----YPDATQVDATPAMIAQGWTPKRMFEESDRFFTSLGLLPMPPEFWNKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPISFRDGANPGFHEAIGDVLALSVATPKHLQSIGLLDKVEDNAESTINFLMSIALDKIAFLPFGYLMDQWRWKVFDGRISSSEYNKEWWNLRMKYQGLCPPVPRTEKDFDPGAKFHIPANVPYIRYFVSFVIQFQFHKGLCDAAGHKGPLHNCDIYQSKEAGKLLSDVMKMGFSKPWPEAMKIITGQPKMSVQPLMEYFKPLIEWLEKENEKNGDVLGW 1249

HSP 2 Score: 373.244 bits (957), Expect = 9.406e-113
Identity = 205/516 (39.73%), Postives = 309/516 (59.88%), Query Frame = 3 
Query:  495 FSSPNVRKILDKLSKTVRSQDENISRNLV-EVKSKIEYIYNNGKPCFGI--CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQN-DFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            F++P+++KI+ K++    +      R L   + S+++ IY+  K C     C  + EP + ++    + Y +L   W  W N +G  +++L+ + V++ N  ++ +GF D   +     +E   FK+ +  L++ + PLY+ LH+FVR  L+ YY P   +  GPIPAH+ GN+WSQ W NI+ ++      N  N D      AK    +   MF +AEEF+ S+GL +M  EFW++S++E+   GR + CH SA DF N  D+RI  CT   +    T+HHEMGH+EY++ Y   P  +R  AN GFHEAIGD ++L+V TP+HLH I LL ++    E DI YL+  ALEK+AFLPF   +D + WSV++G  P  + N  WW L  KYQGI PP  R+E+ FDAG KYHI  + PYIRYF+SFI+QFQF+E +C  +G+ GPLH+CD Y+S +AG  L ++LK G    W + ++   GT ++ +  L+ +F P+  WL+ +N      +GW
Sbjct:  142 FTNPDLKKIIKKINVLEAANLAITDRELYNTILSQMDSIYSTAKVCPSPEECW-SLEPELQEIMATSRSYKRLLYAWEGWHNSSGVPLKSLYAEFVKISNKASQMDGFKDTGEY-WRSWYESPTFKQDLENLFKQLEPLYQNLHAFVRRKLYDYYGPKYINLKGPIPAHLLGNMWSQTWNNIYNMMIPF--PNRPNVDVTNTMIAK--GYNATHMFRVAEEFFTSLGLLEMPPEFWDKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVSFRRGANPGFHEAIGDVLSLSVSTPKHLHSIDLLDQLTDDAESDINYLLKMALEKIAFLPFGYLIDQWRWSVFSGETPPDRYNADWWYLRTKYQGICPPTRRTEEHFDAGGKYHIPGNTPYIRYFVSFILQFQFHEKLCKEAGHTGPLHKCDIYKSREAGAVLEKVLKAGSSEPWTQVLQEALGTDKMDATPLMSYFLPVTTWLREQNEKTGETLGW 651
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Zebrafish
Match: ace2 (angiotensin I converting enzyme 2 [Source:ZFIN;Acc:ZDB-GENE-041114-6])

HSP 1 Score: 314.309 bits (804), Expect = 6.569e-95
Identity = 193/595 (32.44%), Postives = 320/595 (53.78%), Query Frame = 3 
Query:  297 ENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKL-SKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG----EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFIL--FEDFEEENF---KETVIQ----LYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLP-EIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRV-GW*AN 2033
            E+ A+ +L K +E       +Y   ++ Y ++I++ N +   +   I+ +  N +  ++  +   + S P ++  L KL  K   +   + +  L  + S++  IYN    C  I  P      EP +  +  + +DYD+    W  WR  TG ++R L+ K V+L+N  A+ N + D   +    +E  ++  +   ++ VI+    +Y+ ILPLYKELH++VR  L   YPG    +  +PAH+ G++W + WTN++ ++   +    + D    ++   +     ++F+ AE+F+ S+ +  M + FW  S+  +   R + CH +A D  N  D+RI MCTK +++DF T+HHEMGH +Y MAY   P   R+ AN GFHEA+G+ ++L+  TP HL  +GLLP +  +  E DI +L+  AL  V  LPF   ++ + W V+   IP  +  + WW +  +  G+   V R E   D  A +H++    +IRYF   I QFQF E++C  +G+ GPL++CD   S KAG+KL  ML+ G   +W   ++ + GT ++ S  LL +F  L  WLK +N+  +NRV GW  N
Sbjct:   21 EDRAREFLNKFDEEASDIMYQYTLASWAYNTDISQENADKEAEAYAIWSEYYNKMSEESNAYPIDQISDPIIKMQLQKLQDKGSGALSPDKASELRNIMSEMSTIYNTATVC-KIDDPTDCQTLEPGLESIMAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNNYEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYPGHIGSDACLPAHLLGDMWGRFWTNLYPLM---IPYPDRPDIDVSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMFDNFWNNSMFIKPEERDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTRTIYQFQFQEALCKAAGHTGPLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEENQK-NNRVPGWNVN 610
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Zebrafish
Match: ace2 (angiotensin I converting enzyme 2 [Source:ZFIN;Acc:ZDB-GENE-041114-6])

HSP 1 Score: 313.923 bits (803), Expect = 1.669e-94
Identity = 193/595 (32.44%), Postives = 320/595 (53.78%), Query Frame = 3 
Query:  297 ENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKL-SKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG----EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFIL--FEDFEEENF---KETVIQ----LYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLP-EIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRV-GW*AN 2033
            E+ A+ +L K +E       +Y   ++ Y ++I++ N +   +   I+ +  N +  ++  +   + S P ++  L KL  K   +   + +  L  + S++  IYN    C  I  P      EP +  +  + +DYD+    W  WR  TG ++R L+ K V+L+N  A+ N + D   +    +E  ++  +   ++ VI+    +Y+ ILPLYKELH++VR  L   YPG    +  +PAH+ G++W + WTN++ ++   +    + D    ++   +     ++F+ AE+F+ S+ +  M + FW  S+  +   R + CH +A D  N  D+RI MCTK +++DF T+HHEMGH +Y MAY   P   R+ AN GFHEA+G+ ++L+  TP HL  +GLLP +  +  E DI +L+  AL  V  LPF   ++ + W V+   IP  +  + WW +  +  G+   V R E   D  A +H++    +IRYF   I QFQF E++C  +G+ GPL++CD   S KAG+KL  ML+ G   +W   ++ + GT ++ S  LL +F  L  WLK +N+  +NRV GW  N
Sbjct:   21 EDRAREFLNKFDEEASDIMYQYTLASWAYNTDISQENADKEAEAYAIWSEYYNKMSEESNAYPIDQISDPIIKMQLQKLQDKGSGALSPDKASELRNIMSEMSTIYNTATVC-KIDDPTDCQTLEPGLESIMAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNNYEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYPGHIGSDACLPAHLLGDMWGRFWTNLYPLM---IPYPDRPDIDVSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMFDNFWNNSMFIKPEERDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTRTIYQFQFQEALCKAAGHTGPLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEENQK-NNRVPGWNVN 610
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634])

HSP 1 Score: 419.853 bits (1078), Expect = 7.014e-137
Identity = 225/534 (42.13%), Postives = 334/534 (62.55%), Query Frame = 3 
Query:  450 GNSIQ--LKAKKFQWKRFSSPNVRKILDKLS---KTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGI---CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            G+++Q  L+A+ + +  F  P  ++IL KLS   K   S++E    N  ++ S +E IY+  K C      C P  +P + ++  K +DYD+L   W  WR+ +G +IR  + + V+L N  A+ NG++D  ++     +E    +  V +LY+ + PLY  LH++VR  L+K Y  K  +  GPIPAH+ GN+W+Q W+NI+E++       Y N     A+  +   + ++MFE ++ F+ S+GL  M  EFW++S++E+   R + CH SA DF N  D+RI  CT  +++D  T+HHEMGH++YF+ Y   P  +R  AN GFHEAIGD +AL+V TP+HL  IGLL ++  + E DI YLM  AL+K+AFLPF   MD + W V++G  P S+ N+ WW+L LKYQG+ PPV R+E DFD GAK+HI  SVPYIRYFISF+IQFQF+E++C  +  +GPLH+CD YQS +AG  L + +K G    W E M+ +TG + + + +LLK+F+PL  WL  +N      +GW
Sbjct:    3 GHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQKEYN--QITSDMETIYSVAKVCKDGNTNCHPL-DPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVP-----YPNAAQVDATPAMINWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 527
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634])

HSP 1 Score: 431.795 bits (1109), Expect = 1.913e-134
Identity = 238/597 (39.87%), Postives = 361/597 (60.47%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQ--LKAKKFQWKRFSSPNVRKILDKLS---KTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGI---CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            + YP   E+ +NE  A ++L    +      N Y   ++ Y +NI + N +++    +     G+++Q  L+A+ + +  F  P  ++IL KLS   K   S++E    N  ++ S +E IY+  K C      C P  +P + ++  K +DYD+L   W  WR+ +G +IR  + + V+L N  A+ NG++D  ++     +E    +  V +LY+ + PLY  LH++VR  L+K Y  K  +  GPIPAH+ GN+W+Q W+NI+E++       Y N     A+  +   + ++MFE ++ F+ S+GL  M  EFW++S++E+   R + CH SA DF N  D+RI  CT  +++D  T+HHEMGH++YF+ Y   P  +R  AN GFHEAIGD +AL+V TP+HL  IGLL ++  + E DI YLM  AL+K+AFLPF   MD + W V++G  P S+ N+ WW+L LKYQG+ PPV R+E DFD GAK+HI  SVPYIRYFISF+IQFQF+E++C  +  +GPLH+CD YQS +AG  L + +K G    W E M+ +TG + + + +LLK+F+PL  WL  +N      +GW
Sbjct:  628 DGYPGDIEKIANEKEADTFLSDYTKSAEVVWNDYTEASWAYNTNITEANKQVMLDKNLAMS--GHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQKEYN--QITSDMETIYSVAKVCKDGNTNCHPL-DPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVP-----YPNAAQVDATPAMINWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1213

HSP 2 Score: 382.874 bits (982), Expect = 2.923e-116
Identity = 207/534 (38.76%), Postives = 324/534 (60.67%), Query Frame = 3 
Query:  465 LKAKKF---QWKRFSSPNVRKILDKLSKTVRSQDENIS--RNLVEVKSKIEYIYNNGKPCFGICLPAG-------EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +KAK+     W+ F+ P ++KI+  + +T+ + + N++       + S+++ IY+  K    +C P         EP I ++    + Y KL   W  W N  G  ++  +++ V+L N   R +G+ D  ++     +    F+E +  LY+ + PLY  LH+FVR  L++ Y  K+ +  GPIPAH+FGN+WSQQW NI++++   +    + +     + + +  +   MF ++EEF+ S+GL +M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   +    T+HHEMGH+EY++ Y   P  YR  AN GFHEAIGD ++L+V TP HL  IGLL  +   KE DI YL+  ALEK+AFLPF   +D + W+V++G  P ++ N  WW+L  KYQGI PP+ R +  FDAGAKYHI  + PYIRYF+SF++QFQF++++C  + + GPLH CD Y+S +AG  L ++L+ G   +W+E +K +TG++++  G LL++F P+  WL  +N   +  +GW
Sbjct:   93 MKAKELFNDVWENFTDPLLKKIISSI-RTLGASNLNLTAREEYNTILSEMDSIYSTAK----VCPPNATAKCWSLEPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAY-WRSWYASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMM---IPFPDKTNIDVTNTMREKGWNATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDTVTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 617
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634])

HSP 1 Score: 431.795 bits (1109), Expect = 4.444e-134
Identity = 238/597 (39.87%), Postives = 361/597 (60.47%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQ--LKAKKFQWKRFSSPNVRKILDKLS---KTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGI---CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            + YP   E+ +NE  A ++L    +      N Y   ++ Y +NI + N +++    +     G+++Q  L+A+ + +  F  P  ++IL KLS   K   S++E    N  ++ S +E IY+  K C      C P  +P + ++  K +DYD+L   W  WR+ +G +IR  + + V+L N  A+ NG++D  ++     +E    +  V +LY+ + PLY  LH++VR  L+K Y  K  +  GPIPAH+ GN+W+Q W+NI+E++       Y N     A+  +   + ++MFE ++ F+ S+GL  M  EFW++S++E+   R + CH SA DF N  D+RI  CT  +++D  T+HHEMGH++YF+ Y   P  +R  AN GFHEAIGD +AL+V TP+HL  IGLL ++  + E DI YLM  AL+K+AFLPF   MD + W V++G  P S+ N+ WW+L LKYQG+ PPV R+E DFD GAK+HI  SVPYIRYFISF+IQFQF+E++C  +  +GPLH+CD YQS +AG  L + +K G    W E M+ +TG + + + +LLK+F+PL  WL  +N      +GW
Sbjct:  677 DGYPGDIEKIANEKEADTFLSDYTKSAEVVWNDYTEASWAYNTNITEANKQVMLDKNLAMS--GHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQKEYN--QITSDMETIYSVAKVCKDGNTNCHPL-DPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVP-----YPNAAQVDATPAMINWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1262

HSP 2 Score: 382.104 bits (980), Expect = 1.107e-115
Identity = 207/537 (38.55%), Postives = 325/537 (60.52%), Query Frame = 3 
Query:  465 LKAKKF---QWKRFSSPNVRKILDKLSKTVRSQDENISR-----NLVEVKSKIEYIYNNGKPCFGICLPAG-------EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +KAK+     W+ F+ P ++KI+  + +T+ + + N++      +   + S+++ IY+  K    +C P         EP I ++    + Y KL   W  W N  G  ++  +++ V+L N   R +G+ D  ++     +    F+E +  LY+ + PLY  LH+FVR  L++ Y  K+ +  GPIPAH+FGN+WSQQW NI++++   +    + +     + + +  +   MF ++EEF+ S+GL +M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   +    T+HHEMGH+EY++ Y   P  YR  AN GFHEAIGD ++L+V TP HL  IGLL  +   KE DI YL+  ALEK+AFLPF   +D + W+V++G  P ++ N  WW+L  KYQGI PP+ R +  FDAGAKYHI  + PYIRYF+SF++QFQF++++C  + + GPLH CD Y+S +AG  L ++L+ G   +W+E +K +TG++++  G LL++F P+  WL  +N   +  +GW
Sbjct:  139 MKAKELFNDVWENFTDPLLKKIISSI-RTLGASNLNLTTQGKRPSYNTILSEMDSIYSTAK----VCPPNATAKCWSLEPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAY-WRSWYASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMM---IPFPDKTNIDVTNTMREKGWNATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDTVTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 666
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634])

HSP 1 Score: 429.869 bits (1104), Expect = 7.125e-134
Identity = 240/599 (40.07%), Postives = 362/599 (60.43%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQ--LKAKKFQWKRFSSPNVRKILDKLS---KTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGI---CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            + YP   E+ +NE  A ++L    +      N Y   ++ Y +NI + N +L K   +     G+++Q  L+A+ + +  F  P  ++IL KLS   K   S++E    N  ++ S +E IY+  K C      C P  +P + ++  K +DYD+L   W  WR+ +G +IR  + + V+L N  A+ NG++D  ++     +E    +  V +LY+ + PLY  LH++VR  L+K Y  K  +  GPIPAH+ GN+W+Q W+NI+E++       Y N     A+  +  +  + ++MFE ++ F+ S+GL  M  EFW++S++E+   R + CH SA DF N  D+RI  CT  +++D  T+HHEMGH++YF+ Y   P  +R  AN GFHEAIGD +AL+V TP+HL  IGLL ++  + E DI YLM  AL+K+AFLPF   MD + W V++G  P S+ N+ WW+L LKYQG+ PPV R+E DFD GAK+HI  SVPYIRYFISF+IQFQF+E++C  +  +GPLH+CD YQS +AG  L + +K G    W E M+ +TG + + + +LLK+F+PL  WL  +N      +GW
Sbjct:  605 DGYPGDIEKIANEKEADTFLSDYTKSAEVVWNDYTEASWAYNTNITEANKQLDKNLAMS----GHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQKEYN--QITSDMETIYSVAKVCKDGNTNCHPL-DPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVP-----YPNAAQVDATPAMIAKNWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1190

HSP 2 Score: 382.104 bits (980), Expect = 3.217e-116
Identity = 207/534 (38.76%), Postives = 324/534 (60.67%), Query Frame = 3 
Query:  465 LKAKKF---QWKRFSSPNVRKILDKLSKTVRSQDENIS--RNLVEVKSKIEYIYNNGKPCFGICLPAG-------EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +KAK+     W+ F+ P ++KI+  + +T+ + + N++       + S+++ IY+  K    +C P         EP I ++    + Y KL   W  W N  G  ++  +++ V+L N   R +G+ D  ++     +    F+E +  LY+ + PLY  LH+FVR  L++ Y  K+ +  GPIPAH+FGN+WSQQW NI++++   +    + +     + + +  +   MF ++EEF+ S+GL +M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   +    T+HHEMGH+EY++ Y   P  YR  AN GFHEAIGD ++L+V TP HL  IGLL  +   KE DI YL+  ALEK+AFLPF   +D + W+V++G  P ++ N  WW+L  KYQGI PP+ R +  FDAGAKYHI  + PYIRYF+SF++QFQF++++C  + + GPLH CD Y+S +AG  L ++L+ G   +W+E +K +TG++++  G LL++F P+  WL  +N   +  +GW
Sbjct:   70 MKAKELFNDVWENFTDPLLKKIISSI-RTLGASNLNLTAREEYNTILSEMDSIYSTAK----VCPPNATAKCWSLEPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAY-WRSWYASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMM---IPFPDKTNIDVTNTMREKGWNATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDTVTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 594
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Xenopus
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:100144634])

HSP 1 Score: 429.869 bits (1104), Expect = 7.554e-134
Identity = 240/599 (40.07%), Postives = 362/599 (60.43%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQ--LKAKKFQWKRFSSPNVRKILDKLS---KTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGI---CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            + YP   E+ +NE  A ++L    +      N Y   ++ Y +NI + N +L K   +     G+++Q  L+A+ + +  F  P  ++IL KLS   K   S++E    N  ++ S +E IY+  K C      C P  +P + ++  K +DYD+L   W  WR+ +G +IR  + + V+L N  A+ NG++D  ++     +E    +  V +LY+ + PLY  LH++VR  L+K Y  K  +  GPIPAH+ GN+W+Q W+NI+E++       Y N     A+  +  +  + ++MFE ++ F+ S+GL  M  EFW++S++E+   R + CH SA DF N  D+RI  CT  +++D  T+HHEMGH++YF+ Y   P  +R  AN GFHEAIGD +AL+V TP+HL  IGLL ++  + E DI YLM  AL+K+AFLPF   MD + W V++G  P S+ N+ WW+L LKYQG+ PPV R+E DFD GAK+HI  SVPYIRYFISF+IQFQF+E++C  +  +GPLH+CD YQS +AG  L + +K G    W E M+ +TG + + + +LLK+F+PL  WL  +N      +GW
Sbjct:  623 DGYPGDIEKIANEKEADTFLSDYTKSAEVVWNDYTEASWAYNTNITEANKQLDKNLAMS----GHTLQYGLQARNYDYSDFQDPETQRILRKLSEIDKAALSEEEQKEYN--QITSDMETIYSVAKVCKDGNTNCHPL-DPDLTEILAKSRDYDELLFAWKGWRDASGKQIREKYKRYVQLANKAAQLNGYNDNGAY-WRSWYETPTLESDVEKLYDELQPLYLNLHAYVRRALYKKYGDKRINLKGPIPAHLLGNMWAQSWSNIYELLVP-----YPNAAQVDATPAMIAKNWTPKRMFEESDNFFKSLGLLPMPQEFWDKSMIEKPKDREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYKDQPILFREGANPGFHEAIGDVLALSVSTPKHLQSIGLLDKVEDNPESDINYLMSIALDKIAFLPFGFLMDQWRWKVFDGRTPDSEYNQQWWNLRLKYQGLVPPVLRTENDFDPGAKFHIPASVPYIRYFISFVIQFQFHEALCKAANQEGPLHKCDIYQSTQAGKLLGDAMKLGNSKPWPEAMQTITGQRNMSAHALLKYFQPLTDWLIKENTKNGETLGW 1208

HSP 2 Score: 382.489 bits (981), Expect = 3.476e-116
Identity = 207/534 (38.76%), Postives = 324/534 (60.67%), Query Frame = 3 
Query:  465 LKAKKF---QWKRFSSPNVRKILDKLSKTVRSQDENIS--RNLVEVKSKIEYIYNNGKPCFGICLPAG-------EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +KAK+     W+ F+ P ++KI+  + +T+ + + N++       + S+++ IY+  K    +C P         EP I ++    + Y KL   W  W N  G  ++  +++ V+L N   R +G+ D  ++     +    F+E +  LY+ + PLY  LH+FVR  L++ Y  K+ +  GPIPAH+FGN+WSQQW NI++++   +    + +     + + +  +   MF ++EEF+ S+GL +M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   +    T+HHEMGH+EY++ Y   P  YR  AN GFHEAIGD ++L+V TP HL  IGLL  +   KE DI YL+  ALEK+AFLPF   +D + W+V++G  P ++ N  WW+L  KYQGI PP+ R +  FDAGAKYHI  + PYIRYF+SF++QFQF++++C  + + GPLH CD Y+S +AG  L ++L+ G   +W+E +K +TG++++  G LL++F P+  WL  +N   +  +GW
Sbjct:   88 MKAKELFNDVWENFTDPLLKKIISSI-RTLGASNLNLTAREEYNTILSEMDSIYSTAK----VCPPNATAKCWSLEPEITEIMATSRSYKKLLYAWEGWHNSAGIPLKEKYLRFVQLSNEAYRMDGYKDTGAY-WRSWYASPTFEEDLDGLYQQLEPLYLNLHAFVRRKLYERYGAKYINLKGPIPAHLFGNMWSQQWNNIYDMM---IPFPDKTNIDVTNTMREKGWNATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVEYYLQYKDQPVTYRRGANPGFHEAIGDVLSLSVSTPGHLKTIGLLDTVTNDKESDINYLLKMALEKIAFLPFGFLIDQWRWNVFSGRTPPTRYNYDWWNLRTKYQGICPPISRDDNQFDAGAKYHIPGNTPYIRYFVSFVLQFQFHKALCTAAKHTGPLHTCDIYRSQEAGKILGDVLRSGSSKSWQEVLKDMTGSEKMDVGPLLEYFTPVTQWLIEQNTKNNEILGW 612
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Mouse
Match: Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:MGI Symbol;Acc:MGI:87874])

HSP 1 Score: 392.119 bits (1006), Expect = 7.603e-125
Identity = 218/570 (38.25%), Postives = 338/570 (59.30%), Query Frame = 3 
Query:  354 NRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEY---------IYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            N YA  N++Y +NI     ++L +              +AK F    F + ++++I+ KL        +N+ R ++  K   EY          Y+    C+  G C+P  EP + ++    + Y++L   W +WR+  G  I   F K VE  N  A+ NG++D A       +E +N ++ + +LY+ + PLY  LH++VR  L ++Y  ++ + +GPIPAH+ GN+W+Q W+NI+++V     +   N    +A  K +  + R++F+ A+ F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  ++ D    HHEMGHI+YFM Y  LP  +R  AN GFHEAIGD +AL+V TP+HL+ + LL       E+DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV RS+ DFD G+K+H+  +VPY+RYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG  L + +K G    W E MK++TG   + + +++ +F+PL  WL  +NR     +GW
Sbjct:   90 NEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKL--------QNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPL-EPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTD-AGDSWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSA--PNIDATEAMIK-QGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 646
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Mouse
Match: Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:MGI Symbol;Acc:MGI:87874])

HSP 1 Score: 393.275 bits (1009), Expect = 2.437e-122
Identity = 223/601 (37.10%), Postives = 352/601 (58.57%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEY---------IYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++YPE  +  ++E  A  ++ + +       N YA  N++Y +NI     ++L +              +AK F    F + ++++I+ KL        +N+ R ++  K   EY          Y+    C+  G C+P  EP + ++    + Y++L   W +WR+  G  I   F K VE  N  A+ NG++D A       +E +N ++ + +LY+ + PLY  LH++VR  L ++Y  ++ + +GPIPAH+ GN+W+Q W+NI+++V     +   N    +A  K +  + R++F+ A+ F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  ++ D    HHEMGHI+YFM Y  LP  +R  AN GFHEAIGD +AL+V TP+HL+ + LL       E+DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV RS+ DFD G+K+H+  +VPY+RYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG  L + +K G    W E MK++TG   + + +++ +F+PL  WL  +NR     +GW
Sbjct:  406 DNYPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKL--------QNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPL-EPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTD-AGDSWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSA--PNIDATEAMIK-QGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 993

HSP 2 Score: 336.65 bits (862), Expect = 2.892e-101
Identity = 177/402 (44.03%), Postives = 258/402 (64.18%), Query Frame = 3 
Query:  843 FEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +E  +F+E++  +Y  + PLY  LH++VR  L + Y  K+ +  GPIPAH+ G++W+Q W NI+++V           F ++ +  +    V+K      MF ++EEF+ S+GL  M  EFW  S++E+   GR + CH SA DF N  D+RI  CT+  +    T+HHEMGH++Y++ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGLL  +    E DI YL+  ALEK+AFLPF   +D + W V++G  P S+ N  WW L  KYQGI PPV R+E  FDAGAK+HI    PYIRYF+SF++QFQF++++C  +G++GPLH+CD YQS +AG KL ++L+ G    W+E +K L G+  + + +LL++F+P+  WL+ +N+     +GW
Sbjct:    3 YESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVP---------FPDKPNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 395
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Mouse
Match: Ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:MGI Symbol;Acc:MGI:87874])

HSP 1 Score: 394.045 bits (1011), Expect = 2.289e-120
Identity = 223/601 (37.10%), Postives = 352/601 (58.57%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEY---------IYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++YPE  +  ++E  A  ++ + +       N YA  N++Y +NI     ++L +              +AK F    F + ++++I+ KL        +N+ R ++  K   EY          Y+    C+  G C+P  EP + ++    + Y++L   W +WR+  G  I   F K VE  N  A+ NG++D A       +E +N ++ + +LY+ + PLY  LH++VR  L ++Y  ++ + +GPIPAH+ GN+W+Q W+NI+++V     +   N    +A  K +  + R++F+ A+ F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  ++ D    HHEMGHI+YFM Y  LP  +R  AN GFHEAIGD +AL+V TP+HL+ + LL       E+DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV RS+ DFD G+K+H+  +VPY+RYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG  L + +K G    W E MK++TG   + + +++ +F+PL  WL  +NR     +GW
Sbjct:  639 DNYPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKL--------QNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPL-EPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTD-AGDSWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSA--PNIDATEAMIK-QGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1226

HSP 2 Score: 373.244 bits (957), Expect = 8.352e-113
Identity = 210/568 (36.97%), Postives = 331/568 (58.27%), Query Frame = 3 
Query:  372 NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQ---WKRFSSPNVRKILDKLSKTVRSQDENISRNLV--EVKSKIEYIYNNGKPCF----GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ + +NI + N    ++  ++  +       KAK+     W+ F+   +R+I+  + +T+   +  +++      + S +  IY+ GK CF      C  + +P + ++    + Y KL   W  W +  G  ++ L+     + N   R++ FSD  +F     +E  +F+E++  +Y  + PLY  LH++VR  L + Y  K+ +  GPIPAH+ G++W+Q W NI+++V           F ++ +  +    V+K      MF ++EEF+ S+GL  M  EFW  S++E+   GR + CH SA DF N  D+RI  CT+  +    T+HHEMGH++Y++ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGLL  +    E DI YL+  ALEK+AFLPF   +D + W V++G  P S+ N  WW L  KYQGI PPV R+E  FDAGAK+HI    PYIRYF+SF++QFQF++++C  +G++GPLH+CD YQS +AG KL ++L+ G    W+E +K L G+  + + +LL++F+P+  WL+ +N+     +GW
Sbjct:   73 SWAHDTNITEENARRQEEAALVSQEFAEVWGKKAKELYESIWQNFTDSKLRRIIGSI-RTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCW-SLDPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWR-SWYESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVP---------FPDKPNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 628
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Mouse
Match: Ace3 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 [Source:MGI Symbol;Acc:MGI:3644400])

HSP 1 Score: 360.147 bits (923), Expect = 1.180e-112
Identity = 203/566 (35.87%), Postives = 324/566 (57.24%), Query Frame = 3 
Query:  354 NRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYI---YNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASA--KLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            N +    + Y +NI K N + + + +    +       +A+ F+   F + +V+++L KL    +S     + +L+E    + Y+   YN  + C   G CL   EP + ++    +D  +L   W  WR+  G ++R +F   V L N  A+ NG+ D+ + +    +E +  +E + QLY+ + PLY  LH++VR  L++YY P   D  GPIPAH+ GN+W+Q W NI ++V       Y     E  +A  K++     KMFE A  F+ S+G+      FW +S++E+   GR ++CH S+ +F    D+R+  CT+  L D  ++ H+MGHI+YF+ Y  L   Y+  A+  F EA+G  IAL+V + ++L   GLL +  +  E ++ +L+G ALEK+AF+PF+  +D + W +++GTI     N+ WW+  LKYQG+ PPV RS+ DFD GAK+HI  +VPYIRYF+  I+QFQ +E++C+ SG+ GPLH+CD Y S  AG  L ++LK G    WRE ++ +TG   I + + L +F+PL  WL  +N    + +GW
Sbjct:   54 NEFMEATWNYVTNITKQNQKNMLQKEADRSQFMLYFSTRARMFRTDHFLNQDVKRMLRKLQNIDKSALP--TEDLLEYNRLLTYMETAYNRAEVCLDEGPCLTL-EPDLQEIMATSRDQKELLWAWQGWRDAVGRQLRPVFEDYVRLSNKAAQYNGYKDMGA-LWRSKYESDTLEEDLEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLP-----YPTKAPEDITAIMKIQHWRPEKMFEEANLFFTSMGMLPAPPAFWIKSMMEKPADGREVECHTSSWNFYKFNDFRVKKCTEVTLEDLLSVFHQMGHIQYFLQYQNLSVIYQEGASPAFEEAVGSVIALSVSSHKYLLARGLLSQPHQDSEEEVNFLLGIALEKIAFIPFSYLVDKFRWKIFDGTISKITYNQEWWNFRLKYQGLCPPVPRSDDDFDPGAKFHIPANVPYIRYFLGLILQFQLHEALCEASGHVGPLHQCDNYNSKVAGKILGDLLKLGSSRPWREVLQEVTGESNISTKAFLTYFKPLMDWLVTENVKQGDTLGW 610
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Mouse
Match: Ace2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [Source:MGI Symbol;Acc:MGI:1917258])

HSP 1 Score: 305.064 bits (780), Expect = 3.097e-91
Identity = 187/575 (32.52%), Postives = 302/575 (52.52%), Query Frame = 3 
Query:  372 NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKT---VRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG-------EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEE----------NFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEI-VKKCMKSNYQNDFHEQASAKLEK-LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVV-EQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLP-EIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ Y +NI + N + + +    +          A+ F  +   +P +++ L  L ++     S D+N  + L  + + +  IY+ GK    +C P         EP + ++     DY+     W  WR   G ++R L+ + V L+N  AR N ++D   +    D+E E             E V + +  I PLY+ LH++VR  L   YP      G +PAH+ G++W + WTN++ + V    K N      +   A + +     ++F+ AE+F+ S+GL  MT  FW  S++ E   GR + CH +A D  +G D+RI MCTK  +++F T HHEMGHI+Y MAY++ P   RN AN GFHEA+G+ ++L+  TP+HL  IGLLP +  +  E +I +L+  AL  V  LPF   ++ + W V+ G IP  +  + WW++  +  G+  P+   E   D  + +H++    +IRY+   I QFQF E++C  + Y G LH+CD   S +AG KLL+ML  G    W + ++ + G + +    LL +F+PL  WLK +NR+  + VGW
Sbjct:   47 SWNYNTNITEENAQKMSEAAAKWSAFYEEQSKTAQSFSLQEIQTPIIKRQLQALQQSGSSALSADKN--KQLNTILNTMSTIYSTGK----VCNPKNPQECLLLEPGLDEIMATSTDYNSRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMARANNYNDYGDY-WRGDYEAEGADGYNYNRNQLIEDVERTFAEIKPLYEHLHAYVRRKLMDTYPSYISPTGCLPAHLLGDMWGRFWTNLYPLTVPFAQKPNI-----DVTDAMMNQGWDAERIFQEAEKFFVSVGLPHMTQGFWANSMLTEPADGRKVVCHPTAWDLGHG-DFRIKMCTKVTMDNFLTAHHEMGHIQYDMAYARQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLPSDFQEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFRGEIPKEQWMKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYTRTIYQFQFQEALCQAAKYNGSLHKCDISNSTEAGQKLLKMLSLGNSEPWTKALENVVGARNMDVKPLLNYFQPLFDWLKEQNRN--SFVGW 606
[Close]
BLAST of Angiotensin-converting enzyme vs. UniProt/SwissProt
Match: sp|Q10751|ACE_CHICK (Angiotensin-converting enzyme (Fragment) OS=Gallus gallus OX=9031 GN=ACE PE=2 SV=1)

HSP 1 Score: 405.601 bits (1041), Expect = 9.356e-125
Identity = 233/592 (39.36%), Postives = 352/592 (59.46%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQ-DENISRNLVEVKSKIEYIYNNGKPCF-GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLW-KYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E YPE  ++  +E  AK +L + N       N Y   ++ Y +NI   N E++ +  +   K      ++A++F    F    V +IL+KLS   R+   E+  +    + S +E  Y+  K C         +P + D+    +DY++L   W  W + +GA+I++ + + VEL N  A  NG++D  ++     +E   F+E + +LY  + PLY  LH++VR  L+ KY        GPIPAH+ GN+W+Q W+NIF++V   M            + K +  + + MFE ++ F+ S+GL  M  EFW++S++E+   GR + CH SA DF N  D+RI  CT  +++D  T+HHEMGH++YF+ Y   P  +R+ AN GFHEAIGD +AL+V TP+HLH I LL ++ +++E DI YLM  AL+K+AFLPF   MD + W V++G I   + N+ WW+L LKYQG+ PPV RSE DFD GAK+HI  +VPYIRYF+SF+IQFQF++++C  +G+ GPLH CD YQS +AG  L + +K G    W E M+++TG   + + +L+ +FEPL  WL  KN +    +GW
Sbjct:  532 EGYPEGIDKIVDEAQAKEFLSEYNSTAEVVWNAYTEASWEYNTNITDHNKEVMLEKNLAMSKHTIEYGMRARQFDPSDFQDETVTRILNKLSVLERAALPEDELKEYNTLLSDMETTYSVAKVCRENNTFHPLDPDLTDILATSRDYNELLFAWKGWWDASGAKIKDKYKRYVELSNKAAVLNGYTDNGAYWR-SLYETPTFEEDLERLYLQLQPLYLNLHAYVRRALYNKYGAEHISLKGPIPAHLLGNMWAQSWSNIFDLV---MPFPDATKVDATPAMKQQGWTPKMMFEESDRFFTSLGLIPMPQEFWDKSMIEKPADGREVVCHASAWDFYNRKDFRIKQCTVVNMDDLITVHHEMGHVQYFLQYMDQPISFRDGANPGFHEAIGDVMALSVSTPKHLHSINLLDQVTENEESDINYLMSIALDKIAFLPFGYLMDQWRWKVFDGRIKEDEYNQQWWNLRLKYQGLCPPVPRSEDDFDPGAKFHIPANVPYIRYFVSFVIQFQFHQALCKAAGHTGPLHTCDIYQSKEAGKLLGDAMKLGFSKPWPEAMQLITGQPNMSAEALMSYFEPLMTWLVKKNTENGEVLGW 1119

HSP 2 Score: 377.867 bits (969), Expect = 2.072e-114
Identity = 211/522 (40.42%), Postives = 310/522 (59.39%), Query Frame = 3 
Query:  486 WKRFSSPNVRKILDKLSKTVRSQ---DENISRNLVEVKSKIEYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLW-KYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            W  FS P ++KI+  +     S    D+    N +   S ++ IY+  K C   G C    EP I D+    + Y KL   W  W N  G  +R  + + V L N   + +GF D  S+     ++   F++ +  LY  + PLY  LH+FVR  L+ +Y P   +  GPIPAH+ GN+W+QQW NI++++       Y +  +   +  +  +  +   MF ++EEF+ S+GL +M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   +    T+HHEMGH++Y++ Y   P  +R  AN GFHEAIGD ++L+V TP HL KIGLL    + +E +I YL+  ALEK+AFLPF   +D + W+V++G  P S+ N  WW L  KYQGI  PV R+E +FD GAKYHI  + PYIRYF+SFI+QFQF++++C  + + GPLH CD Y S +AG KL E+LK G   +W+E +  LTGT ++ +G+LL++F P+  WL+ +N   +  +GW
Sbjct:    9 WSNFSDPQLKKIIGSIQTLGPSNLPLDKRQQYNTI--LSDMDKIYSTAKVCLDNGTCWDL-EPDISDIMATSRSYKKLLYAWEGWHNAAGNPLRAKYQEFVTLSNEAYQMDGFEDTGSYWR-SWYDSTTFEDDLEHLYNQLEPLYLNLHAFVRRKLYDRYGPKYINLKGPIPAHLLGNMWAQQWNNIYDLMVP-----YPDKPNLDVTNTMVNQGWNATHMFRVSEEFFTSLGLLEMPPEFWEKSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHVQYYLQYKDQPVSFRGGANPGFHEAIGDVLSLSVSTPSHLQKIGLLSSAVEDEESNINYLLKMALEKIAFLPFGYLIDQWRWNVFSGRTPPSRYNYDWWYLRTKYQGICAPVSRNESNFDPGAKYHIPGNTPYIRYFVSFILQFQFHKALCQAANHTGPLHTCDIYMSKEAGAKLREVLKAGSSKSWQEILFNLTGTDKMDAGALLEYFSPVTTWLQEQNNKTNEVLGW 521
[Close]
BLAST of Angiotensin-converting enzyme vs. UniProt/SwissProt
Match: sp|P12821|ACE_HUMAN (Angiotensin-converting enzyme OS=Homo sapiens OX=9606 GN=ACE PE=1 SV=1)

HSP 1 Score: 396.356 bits (1017), Expect = 1.858e-120
Identity = 227/597 (38.02%), Postives = 346/597 (57.96%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELL--KKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAG-----EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++YPE  +  ++E  A  ++ + +  +    N YA  N+ Y +NI     ++L  K  QI    L    Q  A+KF   +  +  +++I+ K+    R+    +    +E  +KI            +C P G     EP + ++    + Y+ L   W  WR+  G  I   + K VEL N  AR NG+ D A       +E  + ++ + +L++ + PLY  LH++VR  L ++Y  +  +  GPIPAH+ GN+W+Q W+NI+++V     +   +    +A  K +  + R+MF+ A++F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  +L D    HHEMGHI+YFM Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + LL     S E DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV R++ DFD GAK+HI  SVPYIRYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG +L   +K G    W E M+++TG   + + ++L +F+PL  WL+ +N     ++GW
Sbjct:  634 DNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQ--ARKFDVNQLQNTTIKRIIKKVQDLERAA---LPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD-AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLK-QGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221

HSP 2 Score: 382.489 bits (981), Expect = 2.734e-115
Identity = 211/565 (37.35%), Postives = 331/565 (58.58%), Query Frame = 3 
Query:  372 NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQ---WKRFSSPNVRKILDKLSKTVRSQDENISRNLV--EVKSKIEYIYNNGKPCFGICLP-------AGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ + +NI   N    ++  ++  +   +   KAK+     W+ F+ P +R+I+  + +T+ S +  +++      + S +  IY+  K    +CLP       + +P + ++    + Y  L   W  W N  G  ++ L+     L N   +++GF+D  ++     +    F++ +  LY+ + PLY  LH+FVR  L + Y  ++ +  GPIPAH+ G++W+Q W NI+++V        + +    ++   +  +   MF +AEEF+ S+ L  M  EFWE S++E+   GR + CH SA DF N  D+RI  CT+  ++  +T+HHEMGHI+Y++ Y  LP   R  AN GFHEAIGD +AL+V TPEHLHKIGLL  +    E DI YL+  ALEK+AFLPF   +D + W V++G  P S+ N  WW L  KYQGI PPV R+E  FDAGAK+H+    PYIRYF+SF++QFQF+E++C  +GY+GPLH+CD Y+S KAG KL ++L+ G    W+E +K + G   + +  LLK+F+P+  WL+ +N+     +GW
Sbjct:   68 SWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAV-RTLGSANLPLAKRQQYNALLSNMSRIYSTAK----VCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY-WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPD---KPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
[Close]
BLAST of Angiotensin-converting enzyme vs. UniProt/SwissProt
Match: sp|Q9GLN7|ACE_PANTR (Angiotensin-converting enzyme OS=Pan troglodytes OX=9598 GN=ACE PE=3 SV=1)

HSP 1 Score: 394.815 bits (1013), Expect = 5.971e-120
Identity = 229/598 (38.29%), Postives = 349/598 (58.36%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELL--KKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKI----EYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++YPE  +  ++E  A  ++ + +  +    N YA  N+ Y +NI     ++L  K  QI    L    Q  A++F   +  +  +++I+ K+    R+    +    +E  +KI    E  Y+    C   G CL   EP + ++    + Y+ L   W  WR+  G  I   + K VEL N  AR NG+ D A       +E  + ++ + +L++ + PLY  LH++VR  L ++Y  +  +  GPIPAH+ GN+W+Q W+NI+++V     +   +    +A  K +  + R+MF+ A++F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  +L D    HHEMGHI+YFM Y  LP   R  AN GFHEAIGD +AL+V TP+HLH + LL     S E DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV R++ DFD GAK+HI  SVPYIRYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG +L   +K G    W E M+++TG   + + ++L +F+PL  WL+ +N     ++GW
Sbjct:  632 DNYPEGIDLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQ--ARRFDVNQLQNTTIKRIIKKVQDLERAA---LPAQELEEYNKILLDMETTYSVATVCHTNGSCLQL-EPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD-AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDT--TEAMLK-QGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1219

HSP 2 Score: 382.104 bits (980), Expect = 3.536e-115
Identity = 211/565 (37.35%), Postives = 331/565 (58.58%), Query Frame = 3 
Query:  372 NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQ---WKRFSSPNVRKILDKLSKTVRSQDENISRNLV--EVKSKIEYIYNNGKPCFGICLP-------AGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ + +NI   N    ++  ++  +   +   KAK+     W+ F+ P +R+I+  + +T+ S +  +++      + S +  IY+  K    +CLP       + +P + ++    + Y  L   W  W N  G  ++ L+     L N   +++GF+D  ++     +    F++ +  LY+ + PLY  LH+FVR  L + Y  ++ +  GPIPAH+ G++W+Q W NI+++V        + +    ++   +  +   MF +AEEF+ S+ L  M  EFWE S++E+   GR + CH SA DF N  D+RI  CT+  ++  +T+HHEMGHI+Y++ Y  LP   R  AN GFHEAIGD +AL+V TP HLHKIGLL  +    E DI YL+  ALEK+AFLPF   +D + W V++G  P+S+ N  WW L  KYQGI PPV R+E  FDAGAK+H+    PYIRYF+SF++QFQF+E++C  +GY+GPLH+CD YQS KAG KL ++L+ G    W+E +K + G   + +  LLK+F+P+  WL+ +N+     +GW
Sbjct:   66 SWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPVWQNFTDPQLRRIIGAV-RTLGSANLPLAKRQQYNALLSNMSRIYSTAK----VCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWR-SWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPD---KPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRGGANPGFHEAIGDVLALSVSTPAHLHKIGLLDNVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPNSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYQSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 621
[Close]
BLAST of Angiotensin-converting enzyme vs. UniProt/SwissProt
Match: sp|Q50JE5|ACE_MESAU (Angiotensin-converting enzyme OS=Mesocricetus auratus OX=10036 GN=Ace PE=2 SV=1)

HSP 1 Score: 394.815 bits (1013), Expect = 7.979e-120
Identity = 231/608 (37.99%), Postives = 358/608 (58.88%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNIN-KTNLELLKKFQII------YGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEY---------IYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQI-PGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++YPE  +  ++E  A+ ++ + +       N YA  N++Y +NI  + +  LL+K + +      YG L       AKKF    F +  +++I+ K+        +N+ R ++  K   EY          Y+    C+  G CL   EP + ++    + Y++L   W +WR+  G  I  LF K VEL N  A  NG++D         +E ++ ++ + QLY+ + PLY  LH++VR  L ++Y  +  + +GPIPAH+ GN+W+Q W+NI+++V     +   N    +A  K +  + R++F+ A++F+ S+GL  ++ EFW +S++E+   GR + CH SA DF NG D+RI  CT  ++ D    HHEMGHI+YFM Y  LP  +R  AN GFHEAIGD +AL+V TP+HLH + LL       E DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV RS+ DFD G+K+H+  +VPYIRYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG  L + +K G    W E MK++TG   + + +++ +F+PL  WL  +NR     +GW
Sbjct:  640 DNYPEGIDLVTDETEAERFVEEYDRTARVLWNEYAEANWQYNTNITLEASKILLQKNKKVANHTLKYGTL-------AKKFDVSNFQNYTIKRIIKKV--------QNMDRAVLPPKELEEYNQILMDMETTYSIANVCYLNGTCLHL-EPDLTNVMATSRKYEELLWVWKSWRDKVGRAILPLFPKYVELSNKIAHLNGYAD-GGDSWRSSYESKSLEQDLEQLYQELQPLYLNLHAYVRRSLHRHYGSQHINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSA--PNLDATEAMIK-QGWTPRRIFKEADDFFTSLGLLPVSEEFWNKSMLEKPGDGREVVCHASAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGGYEHDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQDDFDPGSKFHVPANVPYIRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADTMKMGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1227

HSP 2 Score: 375.555 bits (963), Expect = 8.737e-113
Identity = 212/565 (37.52%), Postives = 337/565 (59.65%), Query Frame = 3 
Query:  372 NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKK-FQWKR--FSSPNVRKILDKLSKTVRSQDENISRNLV--EVKSKIEYIYNNGKPCFGICLP-------AGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ Y +N+ + N  L ++ ++I+ +       KAK+ F   R  F+   +R++++ + +T+   +  ++R      +++ +  IY+  K    +CLP       + EP + ++    + Y KL   W +W +V G  ++ L+     L N   +++GFSD  ++     ++  +F+ET+  LY  + PLY  LH++VR  L + Y  K+ +  GPIPAH+ G++W+Q W NI+++V   +    + +     +   +  +V  MF +AEEF+ S+GL  M  EFW  S++E+   GR + CH SA DF N  D+RI  CT+  +   +T+HHEMGH++Y++ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGLL  +    E DI YL+  ALEK+AFLPF   +D + W V++G  P S+ N  WW    KYQGI PPV R+E  FDAGAK+HI    PYIRYF+SFI+QFQF++++C  +G++GPLH+CD YQS +AG KL  +L+ G    W+E +K + G+  + + +LL++F+P+  WL+ +N+     +GW
Sbjct:   74 SWAYDTNMTEENARLQEEAELIWQEFAEVWGKKAKELFDAIRQNFTDSKLRRVIETI-RTLGPANLPLARRQQYNSLQNNMNRIYSTSK----VCLPNKTATCWSLEPELTNILASSRSYAKLLFAWESWHDVVGIPLKPLYQDFTALSNEAYKQDGFSDTGAY-WRSAYDSPSFEETLEHLYHQLEPLYLNLHAYVRRALHRRYGDKYINLRGPIPAHLLGDMWAQSWDNIYDMV---VPFPNKPNLDVTNTMVQKGWNVTHMFRVAEEFFTSMGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFFNRKDFRIKQCTRITMEQLSTVHHEMGHVQYYLQYKDLTVPLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDRVANDLESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGHTPPSRYNFDWWYFRTKYQGICPPVVRNETHFDAGAKFHIPSGTPYIRYFVSFILQFQFHQALCKEAGHQGPLHQCDIYQSTQAGAKLQRVLQAGYSRPWQEVLKEMVGSDTLDAQALLEYFQPVIRWLQEQNQRNGEVLGW 629
[Close]
BLAST of Angiotensin-converting enzyme vs. UniProt/SwissProt
Match: sp|P09470|ACE_MOUSE (Angiotensin-converting enzyme OS=Mus musculus OX=10090 GN=Ace PE=1 SV=3)

HSP 1 Score: 394.045 bits (1011), Expect = 1.601e-119
Identity = 223/601 (37.10%), Postives = 352/601 (58.57%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEY---------IYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++YPE  +  ++E  A  ++ + +       N YA  N++Y +NI     ++L +              +AK F    F + ++++I+ KL        +N+ R ++  K   EY          Y+    C+  G C+P  EP + ++    + Y++L   W +WR+  G  I   F K VE  N  A+ NG++D A       +E +N ++ + +LY+ + PLY  LH++VR  L ++Y  ++ + +GPIPAH+ GN+W+Q W+NI+++V     +   N    +A  K +  + R++F+ A+ F+ S+GL  +  EFW +S++E+   GR + CH SA DF NG D+RI  CT  ++ D    HHEMGHI+YFM Y  LP  +R  AN GFHEAIGD +AL+V TP+HL+ + LL       E+DI +LM  AL+K+AF+PF+  +D + W V++G+I     N+ WW L LKYQG+ PPV RS+ DFD G+K+H+  +VPY+RYF+SFIIQFQF+E++C  +G+ GPLH+CD YQS +AG  L + +K G    W E MK++TG   + + +++ +F+PL  WL  +NR     +GW
Sbjct:  639 DNYPEGIDLETDEAKADRFVEEYDRTAQVLLNEYAEANWQYNTNITIEGSKILLEKSTEVSNHTLKYGTRAKTFDVSNFQNSSIKRIIKKL--------QNLDRAVLPPKELEEYNQILLDMETTYSLSNICYTNGTCMPL-EPDLTNMMATSRKYEELLWAWKSWRDKVGRAILPFFPKYVEFSNKIAKLNGYTD-AGDSWRSLYESDNLEQDLEKLYQELQPLYLNLHAYVRRSLHRHYGSEYINLDGPIPAHLLGNMWAQTWSNIYDLVAPFPSA--PNIDATEAMIK-QGWTPRRIFKEADNFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHPSAWDFYNGKDFRIKQCTSVNMEDLVIAHHEMGHIQYFMQYKDLPVTFREGANPGFHEAIGDIMALSVSTPKHLYSLNLLSTEGSGYEYDINFLMKMALDKIAFIPFSYLIDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRSQGDFDPGSKFHVPANVPYVRYFVSFIIQFQFHEALCRAAGHTGPLHKCDIYQSKEAGKLLADAMKLGYSKPWPEAMKLITGQPNMSASAMMNYFKPLTEWLVTENRRHGETLGW 1226

HSP 2 Score: 373.244 bits (957), Expect = 5.842e-112
Identity = 210/568 (36.97%), Postives = 331/568 (58.27%), Query Frame = 3 
Query:  372 NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQ---WKRFSSPNVRKILDKLSKTVRSQDENISRNLV--EVKSKIEYIYNNGKPCF----GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ + +NI + N    ++  ++  +       KAK+     W+ F+   +R+I+  + +T+   +  +++      + S +  IY+ GK CF      C  + +P + ++    + Y KL   W  W +  G  ++ L+     + N   R++ FSD  +F     +E  +F+E++  +Y  + PLY  LH++VR  L + Y  K+ +  GPIPAH+ G++W+Q W NI+++V           F ++ +  +    V+K      MF ++EEF+ S+GL  M  EFW  S++E+   GR + CH SA DF N  D+RI  CT+  +    T+HHEMGH++Y++ Y  L    R  AN GFHEAIGD +AL+V TP HLHKIGLL  +    E DI YL+  ALEK+AFLPF   +D + W V++G  P S+ N  WW L  KYQGI PPV R+E  FDAGAK+HI    PYIRYF+SF++QFQF++++C  +G++GPLH+CD YQS +AG KL ++L+ G    W+E +K L G+  + + +LL++F+P+  WL+ +N+     +GW
Sbjct:   73 SWAHDTNITEENARRQEEAALVSQEFAEVWGKKAKELYESIWQNFTDSKLRRIIGSI-RTLGPANLPLAQRQQYNSLLSNMSRIYSTGKVCFPNKTATCW-SLDPELTNILASSRSYAKLLFAWEGWHDAVGIPLKPLYQDFTAISNEAYRQDDFSDTGAFWR-SWYESPSFEESLEHIYHQLEPLYLNLHAYVRRALHRRYGDKYVNLRGPIPAHLLGDMWAQSWENIYDMVVP---------FPDKPNLDVTSTMVQKGWNATHMFRVSEEFFTSLGLSPMPPEFWAESMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTRVTMEQLATVHHEMGHVQYYLQYKDLHVSLRRGANPGFHEAIGDVLALSVSTPAHLHKIGLLDHVTNDIESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVARNETHFDAGAKFHIPNVTPYIRYFVSFVLQFQFHQALCKEAGHQGPLHQCDIYQSAQAGAKLKQVLQAGCSRPWQEVLKDLVGSDALDAKALLEYFQPVSQWLEEQNQRNGEVLGW 628
[Close]
BLAST of Angiotensin-converting enzyme vs. TrEMBL
Match: I1ZIB1 (Angiotensin-converting enzyme (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 627.476 bits (1617), Expect = 0.000e+0
Identity = 298/590 (50.51%), Postives = 417/590 (70.68%), Query Frame = 3 
Query:  258 LEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLP-EIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            LE YP VC  +S+ENCA+ WL +VNEI IRN+NR AN+N++Y +NIN  NL  L K +     L   + LKAKKF+ K F SP V++ L+ L K+ R  D + +  L++++ +IE IYN   PCF  C P GEP II++F + KDYD L GYWVAWRN TG+RIRNLF++++ LEN  A ++GF D A F L  DF+E NF + +   ++ I  LYKELH +VR+CL KYYP +F+K+GPIPAHI G+ WS+ W N+F I+KKC K+ ++ D  ++    + KL+V +MF+++E FY+S+G+  MT+EFW+RS+ +++  +++DCH  +  F NGVD+RI MCT KDL D T+I HEMGHI+YFMAY  L  ++R SANSGF E  GD + LA +TP +L KIGLL   I   +  +I YL+ SAL+ + F+PFA+ ++ Y+ SVYNG++ ++++N+ +WD+  K QGI PPVER+E  FDAGAKYH+A    Y R+  S++ Q+  +E+MC+LSGYKGPLH+C F+ S + G K LEM+K G   NWR+TMKILTGT  + S SLL F+ PL+ WLK KN++L+ + GW
Sbjct:    2 LEPYPNVCNGHSDENCARKWLQRVNEIMIRNNNRLANVNFKYATNINGNNLRELIKMKKKSAILSWKMHLKAKKFRLKFFKSPWVKRSLEMLKKSSRIFDSSTTLRLIDIRFQIENIYNTATPCFKGCQPPGEPGIIEIFNRVKDYDDLAGYWVAWRNATGSRIRNLFIERMNLENQKATDSGFHDSAEFKLATDFQETNFSQKLRNHFDNIFSLYKELHGYVRHCLHKYYPNRFNKSGPIPAHIVGSPWSESWHNVFSILKKCHKNIHEYDLRKEIDENIGKLTVHEMFKLSESFYSSLGMHNMTDEFWKRSITKKLKHKIMDCHPYSDSFENGVDFRIKMCTVKDLKDLTSIFHEMGHIQYFMAYRNLSVWFRESANSGFAELFGDVMGLAFRTPAYLRKIGLLSTNINNLRNSEINYLLTSALDNIVFIPFAISIEEYVNSVYNGSVGNNEMNKIYWDIVRKNQGIVPPVERTENYFDAGAKYHVAIGFAYTRHLFSYLFQYNIFEAMCNLSGYKGPLHQCHFFNSKEVGAKTLEMMKLGNTRNWRKTMKILTGTTSLNSDSLLTFYHPLYEWLKKKNKELNVKTGW 591
[Close]
BLAST of Angiotensin-converting enzyme vs. TrEMBL
Match: A0A1S3GZX9 (Angiotensin-converting enzyme OS=Lingula unguis OX=7574 GN=LOC106150791 PE=3 SV=1)

HSP 1 Score: 455.292 bits (1170), Expect = 7.365e-147
Identity = 257/630 (40.79%), Postives = 385/630 (61.11%), Query Frame = 3 
Query:  195 LINSHNIYQKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKR---FSSPNVRKI-LDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCF----GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK--LSVRKMFEMAEEFYNSIGLFKMTNEFWERS-VVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEF----DIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW*ANN 2036
            L  S    ++Q+ D   +  +++ + +   +   E  A++WL   N           NLN+ Y +NI+  N + ++  Q+   +       +A+++  K+   FS   +R+  L  +  ++R  D+   R +  + S++E IY+ GK C       CLP  EP +++L    +DYD+L   W +WR+VTG  IR+L+ + V  +N  A+ENGF+D+  F    +FE++N  + V  L++ + PLY++LH++VR  L   Y  K+    GPIPAH+ GN+W+QQW  I ++++      Y N      ++ L+K   +V+KMF+ AE F+ S+G+  MT EFWE+S VV+   GR + CH SA DF N  DYRI MCT+ D ++   IHHEMGH++Y+M YS  P  YRN AN+GFHEA+GDTIAL+V TPEHLHK+ LL +I   KE     D+ +LM  AL+K+AFLPF L +D + W V+ G   +S  N+ WWDL L+YQGI PPV RSE DFD GAK+H+  +VPYIRYF+SF+IQFQF  ++CD +G+ GP+H CD YQS  AG KL +ML  G    W + M++LTG +EI   ++L++F+PL  +L  +N++    +GW  N+
Sbjct:   15 LCRSDEELREQLIDMLEDAFKVDKFSDGKFDAGVEEKAEAWLKDYNTKLAVRSGIACNLNWNYETNISNANAKKIENNQVEQAEWNRKKAQEAREWLKKKTSKFSEDTLRQFKLITMDASLR--DDADVRRMSYLLSQMESIYDKGKVCRPHSEASCLPL-EPDLVNLMMTSRDYDELLWAWKSWRDVTGPPIRDLYREFVVFQNKAAKENGFADMGEFWRISNFEDKNLDKIVDGLFDQVKPLYQQLHAYVRRKLINQYGEKYVSPTGPIPAHLLGNMWAQQWDLILDLLQP-----YPNVPSVDVTSALKKQNYTVQKMFKTAEAFFCSLGMDNMTKEFWEKSMVVKPTDGREVQCHASAEDFHNASDYRIKMCTEIDYDNLYVIHHEMGHVQYYMQYSHQPDIYRNGANAGFHEAVGDTIALSVATPEHLHKLKLLDDIGDDKELREKQDLNFLMKMALQKLAFLPFGLLIDKWRWDVFRGHTNASNYNQKWWDLRLRYQGIAPPVPRSELDFDPGAKFHVPANVPYIRYFVSFLIQFQFQRALCDAAGHTGPIHHCDIYQSTAAGEKLKKMLSLGSSRPWPDAMEVLTGQREIDPSAILEYFKPLQDFLVKENKN--EIIGWEENS 634
[Close]
BLAST of Angiotensin-converting enzyme vs. TrEMBL
Match: A0A4Y2HGM0 (Angiotensin-converting enzyme OS=Araneus ventricosus OX=182803 GN=ACE_6 PE=3 SV=1)

HSP 1 Score: 440.654 bits (1132), Expect = 1.466e-141
Identity = 242/583 (41.51%), Postives = 360/583 (61.75%), Query Frame = 3 
Query:  342 IRNDNRYANL--------NYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVR-----KILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPC-FGI-----CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYP-GKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTG--TKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +RN++R A++        N+ Y SN+ + N + + + +  Y +        A  F WK F   NV      K L  L K     D+   + L E+ + ++ IY   K C F       C  + EP I ++    ++  +L   W  WR+VTG  +++ F++ VEL N  A  NGF D    +  E +E E F++ + +L+  + P Y++LH++VR  L + YP      NGPIPAH+ GN+W+Q+W NIF+IVK     N+  D  E    K  K++   MF+M+EEF+ S+GL KMT +FW RS++E+   R + CH SA DF++G D+RI MCT+ ++ D  T+HHEMGHIEY++ Y++ P  +R  AN+GFHEA+GDT+AL+V TP+HL  IGLL E  +  E DI  LM +AL+K+AF+PF+  +DS+ W V++GTI   KLN  WW+L LKYQG+ PPV R+E D DA AKYH+A  VPY+RYF+S+IIQFQF +++CD +GY+GPLH+CD Y++ KAG  L +ML  G   +W + M I+T   T ++ +  ++++F PL  WL+ +N++    VGW
Sbjct:   43 LRNNDRRASVVANKASIANWNYQSNLTEPNKKAMLQMRQEYARFAKETWKNATSFAWKDFKDKNVTAYRWFKSLSNLGKAALPNDK--FKELSELTADMQDIYGKAKVCRFNASDNKPCDLSLEPEITEILIHSRNDAELKHVWSQWRDVTGKVMKDKFLRYVELSNEAACLNGFKDNGE-MWREAYESETFEDEIEELWNTMKPFYEQLHAYVRRRLMQRYPRSGIKPNGPIPAHLLGNMWAQRWANIFDIVKPYPNKNFV-DVTETMEEK--KMTALDMFKMSEEFFASLGLIKMTPQFWNRSIIEKPTDREMVCHASAWDFSDGKDFRIKMCTRVNMEDLITVHHEMGHIEYYLQYARQPLVFRKGANNGFHEAVGDTMALSVATPKHLETIGLLQEYKEDDENDINTLMKTALDKIAFVPFSYLIDSWRWKVFDGTISKDKLNTKWWELRLKYQGLCPPVRRTEDDLDAAAKYHVAADVPYVRYFVSYIIQFQFQKALCDAAGYEGPLHKCDIYKNKKAGQLLSDMLSLGGSVHWNKAMSIITQGKTDKMDAKPMVEYFAPLLKWLREQNKN--ETVGW 617
[Close]
BLAST of Angiotensin-converting enzyme vs. TrEMBL
Match: C3Z9J8 (Angiotensin-converting enzyme OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_287032 PE=3 SV=1)

HSP 1 Score: 431.795 bits (1109), Expect = 1.347e-137
Identity = 254/614 (41.37%), Postives = 355/614 (57.82%), Query Frame = 3 
Query:  222 KQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEEN--FKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVR------KMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIP--KSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            K++ DS   L EL+  P       +E  A  WL + NE   +   + A  N+   +NI   N   +    +   K       + KKF    FS  +V++    ++K+  S DE  +R + E+ +++E IY+    C   G CL   +P +  +  K +DYD+LT  W++WR+  G  +++ + + V L N GA+ENG++D    I    +E  N   +E V  ++E + PLY +LH++VR  L + Y   K    G IPAH+FGN+W+QQW NI++IV           F +Q +  +    V       +MF+ AE F+ SIGL  M   FW++S++ +   R + CH SA DF +  D RI MCTK +  D  TIHHEMGHIEYF+ Y    T YR  AN GFHEA+GDTIAL+V TP HL KIGLL  I   +  EF I  L+  AL KVAFLPF L +D + W V++G I   K N  WW+L +KYQGIKPPVER+++DFD GAKYHI    PYIRYF SF+ QFQF +++C+ +G+ GPLH CD YQS KAG KL  ML  GE   W E MK +TG  ++   ++LK+FEPL  WL+ +N+  +  +GW
Sbjct:   77 KELIDS---LKELKSTP-------DEEKAMKWLEEYNEELRQRQAKSAEANWAQSTNITDENAAKVVDVTMELTKWSLKKMEEGKKFDTSGFSD-DVKRQFGMITKSGSSSDEEKTRKVAEIGTELEKIYSTSTACLPSGTCLKL-DPDLEGILAKSRDYDRLTWAWLSWRDAVGPPMKDKYAEWVALMNEGAQENGYAD-KGVIWRGAYEMPNDTLEEMVDGVWEKVKPLYTQLHAYVRRKLSETYGEDKVLTTGHIPAHLFGNMWAQQWNNIYDIVVP---------FPDQPAIDVSDTMVEQGYDPLRMFKTAEAFFVSIGLRPMPQVFWDKSMIVRPVDREVVCHASAEDFYHDSDVRIKMCTKVNQEDLQTIHHEMGHIEYFLTYEDQKTLYRGGANPGFHEAVGDTIALSVNTPGHLKKIGLLQNIEGNQGTEFQINELLKMALSKVAFLPFGLLIDKWRWRVFSGDITPDKFNTEWWNLRMKYQGIKPPVERTDEDFDPGAKYHIPSGTPYIRYFFSFVAQFQFQQALCEEAGHDGPLHTCDIYQSKKAGAKLKNMLSMGESKPWPEAMKAITGQDKLDPSAILKYFEPLEKWLREQNK--NEELGW 666
[Close]
BLAST of Angiotensin-converting enzyme vs. TrEMBL
Match: A0A2L2Y254 (Angiotensin-converting enzyme (Fragment) OS=Parasteatoda tepidariorum OX=114398 PE=2 SV=1)

HSP 1 Score: 427.943 bits (1099), Expect = 4.357e-137
Identity = 240/576 (41.67%), Postives = 351/576 (60.94%), Query Frame = 3 
Query:  342 IRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVR-----KILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPC------FGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDK-NGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK-LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILT--GTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            I N    A  NY+  SN+ + N +   + +    K        A  F WK F   N       K L  L        EN    L  + + ++ +Y   K C         C  + EP + ++ K+  +Y +L   W  WR+ TG +++N F++ VEL N  A +NGFSD A  +  E+FE +N  E   QL+E I P Y++LH++VR  L K Y     K +GPIPAH+ GN+W+Q W NI+ +V    K        +     LEK ++ R MFE++EEF+ S+GL  MT  FW++S++E+   R + CH SA DF N  D RI MCT+ D+ D  T+HHEMGH+EYF+ Y   P  +RN ANSGFHEAIGD +AL+V TP+H+ KIGLL E+    E +I  L+ +AL+K+AF+PF   +D++ W V++G++ +++LN  WW+L LKYQG+ PPV R+EKD DA AKYH+   VPYIRYF+SF+IQFQF++++CD +G+KGPLH+CD YQ+  AG  L + LK G   +WRE MK++T   T ++ + ++L++F+PL+ WLK +N++ +  +GW
Sbjct:   28 ITNKGVIAQWNYQ--SNLTEHNKKEFLRMEEEMAKFAKETWKNATSFAWKNFKGKNETAYRWFKALSVLGSAALP--ENKFNELGNINADMQDVYAKAKVCSYMSSLLDPCTLSIEPELTEIMKESTNYYELKHVWAQWRDETGKKMKNKFLRYVELSNEAACKNGFSD-AGEMWREEFETDNITEEFDQLWETIKPFYEQLHAYVRRKLIKEYTDIHIKPDGPIPAHLLGNMWAQTWGNIYRLVAPYPKKKAV----DVTDTMLEKKMNARDMFEISEEFFTSLGLIPMTPTFWKKSIIEKPTDREMVCHASAWDFYNDGDVRIKMCTRIDMEDLITVHHEMGHVEYFLQYKVQPVVFRNGANSGFHEAIGDVLALSVATPDHMKKIGLLKEVNHDPEAEINNLLKTALDKIAFVPFGFLIDAWRWRVFDGSVKTNQLNSAWWNLRLKYQGVCPPVLRTEKDLDAAAKYHVIADVPYIRYFVSFVIQFQFHKALCDEAGFKGPLHKCDIYQNKNAGKLLSDTLKLGSSVSWREAMKVITKGKTDKMDASAILEYFKPLYDWLKDQNKNEY--IGW 592
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Cavefish
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:103040258])

HSP 1 Score: 437.187 bits (1123), Expect = 1.151e-136
Identity = 242/597 (40.54%), Postives = 368/597 (61.64%), Query Frame = 3 
Query:  261 EDYPE-VCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRS--QDENISR--NLVEVKSKIEYIYNNGKPC--FGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E YPE V ++ ++E  AK +L + N       N Y   ++ Y +NIN+ N + + +  +       +  L+A+K+    F   +V++IL KLS   R+   D+++    NL+   + +E  Y+  K C   G CLP  +P +  +  + +DYD+L   W  WRN +G  +R  +V+ VEL NL AR NG +D  +F     +E   F+E +  L++ + PLY  LHS+VR  L+K Y  K  +  GPIPAH+ GN+W+Q W+ I ++V+    +  Q D  +   AK       +MF  +E F+ S+GL  M +EFW++S++E+   GR + CH SA DF N  D+RI  CT  +++D  T+HHEMGH++YF+ Y   P  +R+ AN GFHEAIGD +AL+V TP+HLH IGLL ++ ++ E  I +LM  AL+K+AFLPF   MD + W V++G I SS+ N+ WW+L LKYQG+ PPV R+E DFD GAK+HI  +VPY+RYF+SF++QFQF++++CD +G+ GPLH CD YQS +AG  L +++K G    W E M ++TG  ++    L+++F+PL  WL+ +N    + +GW
Sbjct:  621 EGYPEDVADKITDEAQAKQFLAEYNSTAETVWNAYTEASWSYNTNINEANKQNMLEKNLEMANHTKTYGLEARKYDTSDFQDSSVKRILKKLSDLERAVLSDDDLKEYNNLL---ASMETTYSVAKVCKDDGTCLPL-DPDLNKIMAESRDYDELLFAWQGWRNASGRELRQSYVRYVELANLAARSNGHADNGAF-WRSLYETPTFEEDLEALWKDLQPLYLNLHSYVRRALFKKYGAKRINLKGPIPAHLLGNMWAQTWSGIMDLVRPYPNAA-QVDVTQAMIAK--GWDANRMFRESENFFTSVGLLPMPDEFWQKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVINMDDLITVHHEMGHVQYFLQYKDQPISFRDGANPGFHEAIGDVLALSVSTPKHLHTIGLLDKLEENAESTINFLMSIALDKIAFLPFGYLMDQWRWKVFDGRISSSEYNKEWWNLRLKYQGLCPPVTRTEVDFDPGAKFHIPANVPYVRYFVSFVVQFQFHKALCDTAGHTGPLHNCDIYQSKEAGKLLGDVMKLGFSKPWPEAMAMITGQPQMSVQPLMEYFQPLITWLEQENAKNGDVLGW 1209

HSP 2 Score: 374.4 bits (960), Expect = 2.031e-113
Identity = 215/562 (38.26%), Postives = 328/562 (58.36%), Query Frame = 3 
Query:  390 NINKTNLELLKKFQ--IIYGKLGNSIQLKAKKF----QWKRFSSPNVRKILDKLSKTVRSQDENISRNLV-EVKSKIEYIYNNGKPCFGI--CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQIP-GRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            N N TN   L++ Q  +I  +   +  +KAK        + F++P++ KI+ K++    +      R     + S+++ IY+  K C     C  A EP + ++    + Y KL   W  W NV+G  +++L+ + V+L N  +  +GF D  ++     +E   F++ +  L++ + PLY+ LH+FVR  L+ +Y P   +  GPIPAH+ GN+WSQ W NI+         N    F ++ +  +    V K      MF +AEEF+ S+GL +M  +FW++S++E+   GR + CH SA DF N  D+RI  CT   +    T+HHEMGH+EY++ Y   P  +R  AN GFHEA+GD ++L+V TP+HLH IGLL  +P   E DI YL+  ALEK+AFLPF   +D + W V++G  P  + N  WW L  KYQGI PPV R+E+ FD GAKYHI  + PYIRYF+SFI+QFQF++ +C  +G+ GPLH CD Y+S +AG  L ++L+ G    W E ++   GT ++ + +L+++F P+  WL+ +NR     +GW
Sbjct:   60 NTNLTNENSLQQIQASMIEQEFTEAWGMKAKATFPDALMETFTNPDLIKIIKKINVLGAANLPTAERERYNTILSQMDNIYSTAKVCPKPEECW-ALEPELKEILANSQSYKKLLYAWEGWHNVSGIPLKDLYPEFVQLSNNASVMDGFDDTGAY-WRSWYESPTFEQDLENLFKQLQPLYQNLHAFVRRKLYDFYGPKYINLKGPIPAHLLGNMWSQTWNNIY---------NMMIPFPDKPNVDVTNAMVEKNYNATHMFRVAEEFFTSLGLKEMPQKFWDKSMLEKPDDGREVVCHASAWDFYNREDFRIKQCTIVTMEQLFTVHHEMGHVEYYLQYKDQPVSFRRGANPGFHEAVGDVLSLSVSTPKHLHTIGLLDTLPNDNETDINYLLKMALEKIAFLPFGYLIDQWRWGVFSGRTPPERYNAEWWYLRTKYQGICPPVRRTEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHQKLCQEAGHTGPLHTCDIYRSTQAGAVLEKVLQAGSSKPWTEVLQEALGTNKMDAAALMEYFLPVTTWLEEQNRLTGETLGW 610
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Cavefish
Match: ace2 (angiotensin I converting enzyme 2 [Source:NCBI gene;Acc:103030208])

HSP 1 Score: 312.383 bits (799), Expect = 3.811e-94
Identity = 188/592 (31.76%), Postives = 309/592 (52.20%), Query Frame = 3 
Query:  297 ENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLS-KTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLP----AGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASF----ILFED-----FEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLP-EIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E+ AK +L+K +E   R   +Y+  ++ Y +NI   N   L +   I+ +  + +  ++ +F   + S   V   L  L  K   +   + +  L +V +++  IY+ G  C  I  P      EP + ++    +DY +    W  WR   G ++R L+ +  +L+N  A+ N + D   +       ED     +  +     V  +Y  I+PLYKELH++VR  L   YPG    NG +PAH+ G++W + WTN++ +    +    + D     +   +     ++F+ AE+F+ S+ +  M   FW  S++ +   G  + CH +A D  N  D+RI MCTK +++DF T HHEMGH +Y MAY  LP   R+ AN GFHEA+G+ ++L+  TP HL  +GLLP +  +  E DI +L+  AL  VA LPF   ++ + W V+ GTIP  +    WW++  +  G+  P+ R E   D  A +H++    +IRYF   + QFQ  +++C  +G+ GPL++CD   S  AGNKL +ML+ G   +W   ++ + G   + +  LL +F  L+ WLK +N+  +   GW
Sbjct:   21 EDRAKDFLLKFDEDASRLMYQYSLASWAYNTNITTENSNKLAEQGAIWSEYYSRVSEESNEFPIDQMSDELVILQLKSLQDKGSGALSPDKASRLSKVLNEMSTIYSTGTVC-KIDNPFDCQTLEPGLEEIMANSRDYYERLHVWEGWRVQVGKKMRKLYEEYADLKNEAAKLNNYKDYGDYWRANYETEDEPKYSYSRDELMRDVRSIYSEIMPLYKELHAYVRAKLQNTYPGHIASNGGLPAHLLGDMWGRFWTNLYPL---AVPYPDKPDIDVSPAMVAQGWDEERLFKEAEKFFVSVNMSAMFPNFWTNSMLTKPTDGTKVVCHPTAWDMGNREDFRIKMCTKVNMDDFLTAHHEMGHNQYQMAYRHLPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPADFTEDMETDINFLLKQALTIVATLPFTYMLEEWRWQVFQGTIPKDQWMLRWWEMKRELVGVTEPLPRDESYCDPPALFHVSGDYSFIRYFTRTVYQFQLQDALCKEAGHTGPLYKCDITNSTDAGNKLRDMLELGRSKSWTRALEQVCGDTRMDARPLLSYFSTLYEWLKEENQKNNRASGW 608
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Sea Lamprey
Match: ace (angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [Source:ZFIN;Acc:ZDB-GENE-030131-1826])

HSP 1 Score: 413.69 bits (1062), Expect = 1.256e-128
Identity = 221/592 (37.33%), Postives = 357/592 (60.30%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKT-VRSQDENISRNLVEVKSKIEYIYNNGKPCFG-ICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGK-FDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +DYP   ++ ++E  A + L + N    +  + Y   ++ Y ++I + + +L+++  +            A  + W  F    VR+ L K+S+    +  E   +   E+ S++E  Y+  K C G  C+P  +P I  +  + ++YD+L  YW  WR+ +G ++R  +V+ VEL N  A  NGF D  +      ++ E F+  + ++YE + PLY  LH++VR  L ++Y  +  +  GPIPAH+ GN+W+Q W N+  +V     +          + + +K + + MF +++ F+ S+G+  M  EFW++S++E+   GR + CH SA DF N  D+RI  CT   ++D  T+HHEMGH++YF+ Y + P  +R+ AN GFHEAIGD +AL+V TP+HL +IGLL  +  + E DI +L+  AL+K+AFLPF   MD + W V++G IP+   N+ WW+L +KYQG+ PPV R+E DFD G+K+HI  SVPY RYF+SF+IQFQF E++C  +G KG LH+CD Y+S  AG+KL ++++ G    W+E M+++TG + + + +LLK+F+PL  WL  +N+     +GW
Sbjct:  639 DDYPGNLDKITDETQAIALLEEYNTTAEKYWSEYNEASWTYNTDITEEHDKLVQEANLRMANHSLYFGRDALLYDWSNFQDEGVRRQLKKISQIGTAALPETELKEYNEIVSRMETAYSVAKVCRGETCIPL-DPDITAIMAESRNYDELLYYWQGWRDASGRKMREDYVRYVELSNKAAIANGFPDNGA-QWRSAYDTETFEADLERIYEELKPLYLNLHAYVRRKLHQHYGDEHVNLKGPIPAHLLGNMWAQSWNNLNSLVAPFPNAP---SVDATPAMQAQKWTPKMMFNVSDVFFTSLGMIPMPREFWDKSMLEKPTDGREVVCHASAWDFYNRKDFRIKQCTVVTMDDLVTVHHEMGHVQYFLQYKEQPVPFRDGANPGFHEAIGDVMALSVATPKHLKEIGLLETVEDNSESDINFLLSMALDKIAFLPFGFLMDQWRWKVFDGRIPTEDYNKEWWNLRMKYQGLCPPVARTEDDFDPGSKFHIPASVPYDRYFVSFVIQFQFQEALCAAAGQKGDLHKCDIYKSKDAGDKLAKVMQLGSSRRWQEAMEMITGQQNMSAAALLKYFKPLTDWLVKENQKNGEVLGW 1225

HSP 2 Score: 352.829 bits (904), Expect = 3.236e-106
Identity = 202/490 (41.22%), Postives = 290/490 (59.18%), Query Frame = 3 
Query:  591 SKIEYIYNNGKPC------FGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIV---KKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLL-PEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            S ++ IY+ GK C         C P  +P I D+    + Y KL  YW  W NV G  + + + + VEL N  ++ + F+D   +     +E   F++ + ++YE + PLY  LH++VR  L ++Y  KF +  GPIPAH+ GN+WSQQW NIF++V         +  +   EQ        +   MF  +E+F+  +GL +M  EFW  S++E+   GR + CH SA DF N  D+RI  CT   +    T+HHEMGHIEY++ Y      +R  AN GFHEAIGD ++L+V TP HL  IGLL P+    KE DI YLM  ALEK+AFLPF   +D + W V++G  P  + N+ WW L  KYQGI P V R   DFDAGAK+HI  + PYIRYF+SFIIQFQF +++C  +  KGPL++CD  ++  AGN L + ++ G    W E MK +TGT ++ +  L+++F+P+  WL+ +N  ++  +GW
Sbjct:  149 SDMDAIYSTGKVCKPGQTSGTDCAPL-DPTITDILATSRSYKKLLYYWEGWHNVVGRPLHSKYARFVELSNAASQLDDFADTGEY-WRSWYESATFRDDLERIYEELKPLYLNLHAYVRRKLHQHYGEKFVNLKGPIPAHLLGNMWSQQWNNIFDMVVPYPGKTSVDVTDTMVEQG------WNATHMFRTSEDFFKDLGLLEMPPEFWSGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTIPTMEQLFTVHHEMGHIEYYLQYKDQHVSFRGGANPGFHEAIGDVLSLSVSTPTHLKTIGLLGPDYVGDKESDINYLMKMALEKIAFLPFGYLIDLWRWDVFSGKTPPERYNQDWWYLRTKYQGICPGVPRKSTDFDAGAKFHIPGNTPYIRYFVSFIIQFQFQKALCTAAQDKGPLYKCDIDKNQAAGNLLRKAMQMGSSRPWTEVMKEMTGTDKMSALPLIEYFKPVIDWLEKEN--VNETLGW 628
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004373.1 (pep scaffold:Pmarinus_7.0:GL477858:25443:42821:1 gene:ENSPMAG00000003990.1 transcript:ENSPMAT00000004373.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 255.758 bits (652), Expect = 8.161e-78
Identity = 133/349 (38.11%), Postives = 197/349 (56.45%), Query Frame = 3 
Query:  609 YNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK-LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPE--IPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDL 1640
            +++G  CF +     EP +  +    + Y +L  YW  WR   G  +R  +   V+L N  +R +GF+D   F     +E E F+  + +LY+ + PLY  +H++VR  L + Y  +  +  GPIPAH+ G++W+QQW  I+++V         +      SA +E+  +   MF ++EEF+ S+GL +M  EFW  S++E+   GR + CH SA DF N  D+RI  CT   + D    HHEMGH++YF+ Y + P  +R  AN GFHEAIGD +AL+V TP HL KIGLL    +    E DI +L+  AL K+AFLPF   +D + W V++G  P  + N  WW L
Sbjct:   66 HSSGPDCFPL-----EPELDHIMATSRSYTQLLYYWEGWRTDVGRPLRAPYAHFVQLSNEASRADGFADTGEFWR-SVYETETFRADLERLYDELRPLYLHMHAYVRRRLHRRYGERLVNLRGPIPAHLLGDMWAQQWQGIYDLVVPYPGKTRVD----VTSAMVEQGWNTTHMFRVSEEFFTSLGLMEMPPEFWNGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTSVTMTDLVRAHHEMGHVQYFLQYKEQPVPFRRGANPGFHEAIGDVMALSVATPRHLKKIGLLEPSYVEDPAESDINFLLWMALGKIAFLPFGFLVDQWRWDVFSGHTPPGRYNHDWWHL 404
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004370.1 (pep scaffold:Pmarinus_7.0:GL477858:22090:39821:1 gene:ENSPMAG00000003990.1 transcript:ENSPMAT00000004370.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 216.853 bits (551), Expect = 1.906e-63
Identity = 112/292 (38.36%), Postives = 167/292 (57.19%), Query Frame = 3 
Query:  609 YNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK-LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQ-IPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLL 1475
            +++G  CF +     EP +  +    + Y +L  YW  WR   G  +R  +   V+L N  +R +GF+D   F     +E E F+  + +LY+ + PLY  +H++VR  L + Y  +  +  GPIPAH+ G++W+QQW  I+++V         +      SA +E+  +   MF ++EEF+ S+GL +M  EFW  S++E+   GR + CH SA DF N  D+RI  CT   + D    HHEMGH++YF+ Y + P  +R  AN GFHEAIGD +AL+V TP HL KIGLL
Sbjct:  122 HSSGPDCFPL-----EPELDHIMATSRSYTQLLYYWEGWRTDVGRPLRAPYAHFVQLSNEASRADGFADTGEF-WRSVYETETFRADLERLYDELRPLYLHMHAYVRRRLHRRYGERLVNLRGPIPAHLLGDMWAQQWQGIYDLVVPYPGKTRVD----VTSAMVEQGWNTTHMFRVSEEFFTSLGLMEMPPEFWNGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTSVTMTDLVRAHHEMGHVQYFLQYKEQPVPFRRGANPGFHEAIGDVMALSVATPRHLKKIGLL 403
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Nematostella
Match: EDO37947 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEG1])

HSP 1 Score: 385.185 bits (988), Expect = 5.723e-124
Identity = 221/573 (38.57%), Postives = 322/573 (56.20%), Query Frame = 3 
Query:  354 NRYANLNYR--------YGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGK--PCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVR------KMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            NR A   YR        Y +N+   N  L  +  + +     S  + A KF   + S    R+I    +        +I R   E+ S+++ IY++GK     G  L +  P +  +  + +DY++L   W  WR+  G  IR L+ + V++ N GA+ENG+ D   +     +E EN +     LY  + PLY+ELH++VRY L + Y  +      IPAH+FGN+W+Q W NI+++V+          +  Q+S  + +  V+      +M ++AE F+ SIGL  +   F+ RS++ +   R + CH SA DF    D RI  CT    +   T HHE+GHI+YF+ Y+  P  YR  AN GFHEA+GDT++L+V TP HLH+IGLL  +  + E DI  LM  AL KVAFLPF   +D + W V+ G I     N  WW+L  KYQGIKPPV R+E DFD GAKYHI  + PYIRYF+S++IQFQF+++ C+ +G+ GPLH+C  Y S  AG KL  MLK G+   W + +K +TGT+E+  G L ++F+PL  W+K +       +GW
Sbjct:   37 NRRAPFEYRNSELALWNYETNLTDFNQALKTQASLAFSMFTQSALVNASKFDANKLSEDTKRQIKLIAASASPKNPADIKRK-SELNSQMDKIYSSGKVKDANGEML-SLNPDLYKILAESRDYERLLFVWKGWRDAVGPAIRPLYQQFVDISNKGAKENGWKDNGEY-WRSSYEVENLERIAEGLYSDLKPLYQELHAYVRYKLSQQY-SQVKSGDAIPAHLFGNMWAQSWANIYDLVEP---------YGNQSSLDVTRNMVKQGYTELRMVQLAESFFTSIGLDPLPQSFYNRSMIVKPKDRGVVCHASAWDFLISRDVRIKQCTTITHDSLVTTHHELGHIQYFLQYAHQPYEYRTGANPGFHEAVGDTLSLSVDTPAHLHRIGLLDAVSNNTESDINALMKMALSKVAFLPFGFLIDQWRWRVFRGEITPQNYNRKWWELRTKYQGIKPPVCRTENDFDPGAKYHIPANTPYIRYFVSYVIQFQFHKAACEAAGHTGPLHKCSIYNSTAAGGKLGAMLKLGKSKPWPQALKAMTGTEEMDVGPLTEYFKPLITWMKAQRAKHGYPIGW 596
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Nematostella
Match: EDO35659 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKY7])

HSP 1 Score: 395.201 bits (1014), Expect = 6.699e-123
Identity = 220/527 (41.75%), Postives = 325/527 (61.67%), Query Frame = 3 
Query:  468 KAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGK--PCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVR------KMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +AKKF   + S+ + R+ +  +++T  S D+++ + L +V+ K++ IY +GK     G  L + +P +  +    +DY++L   W  WR+ TG  +R L+ + VEL N GA+ENG++D   +     +E +N + +V  LYE + PLY+ELH++VRY L K Y  +    GPIPAH+FGN+W+Q W NI++I++      Y+N    Q S  + K  V       +M ++AE F+ SIGL  +   F+E+S++ +  GR + CH SA DF    D RI  CT    N   T HHE+GHI+Y++ Y   P  YR  AN GFHEA+GDT++L+V TP HL  IGLL  +    + DI  LM  AL KVAFLPF   +D + W V++G I S   N  WW L  KYQGIKPPV R+E DFD GAKYHI  + PYIRYF+SF++QFQF+++ C+ +G++GPLH+C  Y S +AG KL +ML  G+   W   ++ +TGT+++   SL ++F+PL  WLK + ++    +GW
Sbjct:  550 EAKKFDLTKLSN-DTRRQIKMVTETASSSDKDVQKTLNDVEGKMDQIYGSGKVIDTDGSKL-SLDPHLYKILSNSRDYERLKFVWKGWRDATGPELRPLYKQFVELANKGAKENGWADNGEW-WRSWYEIDNLESSVEALYEDLRPLYEELHAYVRYKLSKKY-SQVKPTGPIPAHVFGNMWAQSWVNIYDIIEP-----YEN----QPSLDVTKTMVAQNYTQLRMVQLAESFFTSIGLKALPMSFYEKSMIVKPEGREVQCHASAWDFKINRDVRIKQCTTITHNYLVTTHHELGHIQYYLQYWDQPFEYRTGANPGFHEAVGDTLSLSVDTPTHLKLIGLLDAVSNDSKSDINALMKMALRKVAFLPFGFLIDQWRWKVFSGDITSDNYNREWWKLRTKYQGIKPPVCRTENDFDPGAKYHIPGNTPYIRYFVSFVLQFQFHKAACEAAGHQGPLHKCSIYNSTEAGKKLGDMLSLGKSKPWPLALEQMTGTRKMDVSSLKEYFKPLSDWLKSQRQEYKYTIGW 1063

HSP 2 Score: 337.421 bits (864), Expect = 1.834e-101
Identity = 187/487 (38.40%), Postives = 284/487 (58.32%), Query Frame = 3 
Query:  588 KSKIEYIYNNGK---PCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDF-----ANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +S++  IY++ K   P  G  L +  P + +L    ++  +L   W  WR VTG ++R LF   V L N GA++NGF ++  +     +E  N +E +  +++ +  LY ELH++VR  L + YP        IPAH+ GN+W+Q W NI+ +V+     + +       + + +  +  KM ++AE F+ SIG  K+   F+ +S+ E+   R + CH +A DF         D RI  CT+    D    HHEMGHI YF+ Y   P  YR+ AN  FHEA+GDTIAL+V TP HL K+ LL E  + KE +I  LM  AL K+AFLPF   ++ + W VY G I SS+ N+ WW+L +K+QG++PP+ R E  FD G+K+HIA +  YI+YF+S I+QFQ ++++CD++G   PLH+C  Y S KAG KL  ML+ G    WR+T++  TG++++    L ++F PL+ WL  +      ++GW
Sbjct:    7 ESEMTEIYSSAKVTNPAIGTNL-SLNPQLTELMANSRNSPELLAAWRDWRQVTGPKMRPLFKDCVTLANQGAKDNGFQNMYEYQT-HLYELPNLEEYIDGIWQELKVLYLELHAYVRQRLSEQYPHVLSSQA-IPAHLLGNMWAQNWVNIYPLVEPY---SGKPSLDVTKNLRQQNYTAVKMVQLAEAFFRSIGFEKLPGSFYSKSMFEKPEDREVLCHAAALDFFEKNSKGEKDVRIKQCTEITHQDLIITHHEMGHIYYFLKYWDQPYIYRDGANPAFHEALGDTIALSVDTPRHLVKVKLLDEYMEDKEAEINALMKMALSKIAFLPFGYLLEKWRWQVYTGEIDSSEYNKKWWELRVKHQGVRPPISRDETTFDPGSKFHIAANARYIQYFLSRILQFQLHKTVCDIAGINEPLHKCSIYNSTKAGQKLSAMLEMGRSKPWRDTLEAFTGSRDMSVNPLKEYFHPLYQWLVEQRCQNKYKIGW 487
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Nematostella
Match: EDO29688 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2Y1])

HSP 1 Score: 369.777 bits (948), Expect = 5.542e-120
Identity = 200/467 (42.83%), Postives = 278/467 (59.53%), Query Frame = 3 
Query:  606 IYNNGKPCFGI-----CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK--LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWL 1985
            IY+ GK C  I     C+ + +P + +L  + ++ D+L   W  WR+     +R +F + V+L N GAR++G  D   F   E     +F   + +L+  + PLYKELH++VR+ L K Y G    +GPIPAH+ GN+W+Q W  I+++V+      Y +      +  L K   +  KMF++A+ F+ SIGL  M   FW +S++ +   + + CH SA DF+      I MCT+    D  TIHHEMGH EYF+AY   P  YRN AN GFHEAIGDTIAL+V TP+HL+ +GLL  +PK  E  I +LM  AL  VA LPF   +D + W V  G I  S  N  WW +   YQG+KPPV R+E DFD GAK+HI  + PYI YF+S I+QFQF+ ++C+L+ + GPLH C  YQS +AG K  EML  G    W +T+  LTG +E+ +  LL++F PL  WL
Sbjct:    8 IYSTGKVCLNITRNNTCM-SLDPDLGNLMSRSRNQDELVWAWRGWRDAVAPPVRGMFQQMVDLLNKGARQHGLGDYGHFERGEYEMGNDFTAVIKKLWTDVKPLYKELHAYVRFQLKKKYAG-MSGSGPIPAHLLGNMWAQNWDGIYDMVQP-----YPDATPLDVTPSLIKQHYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFSKMTSGAIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYTLPKGDEASINFLMTQALSHVAPLPFTYLVDQWRWKVLAGEISPSNYNSAWWRMRTLYQGVKPPVARNESDFDPGAKFHIVSNSPYIGYFVSLILQFQFHRALCNLAKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRVWPQTLFKLTGEREMSADPLLEYFAPLRKWL 467
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Nematostella
Match: EDO34063 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQE7])

HSP 1 Score: 369.007 bits (946), Expect = 8.500e-120
Identity = 204/480 (42.50%), Postives = 283/480 (58.96%), Query Frame = 3 
Query:  606 IYNNGKPCFGI-----CLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEK--LSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            IY+ GK C  I     C+ + +P + +L  + ++ D+L   W  WR+     +R +F + V+L N GAR++G  D   F   E     +F   + +L+  + PLYKELH++VR+ L K Y G    +GPIPAH+ GN+W+Q W  I+++V+      Y +      +  L K   +  KMF++A+ F+ SIGL  M   FW +S++ +   + + CH SA DF    D RI MCT+    D  TIHHEMGH EYF+AY   P  YRN AN GFHEAIGDTIAL+V TP+HL+ +GLL  +PK  E  I +LM  AL  VA LPF   +D + W V  G I  S  N  WW +   YQG+KPPV R+E DFD GAK+HI  + PYI YF+S I+QFQF+ ++C+L  + GPLH C  YQS +AG K  EML  G    W +T+  LTG +E+ +  LL++F PL  WL +     +  +GW
Sbjct:    8 IYSTGKVCLNITRNNTCM-SLDPDLGNLMSRSRNQDELVWAWRGWRDAVAPPVRGMFQQMVDLLNKGARQHGLGDYGHFERGEYEMGNDFTAVIKKLWTDVKPLYKELHAYVRFQLKKKYAG-MSGSGPIPAHLLGNMWAQNWDGIYDMVQP-----YPDATPLDVTPSLIKQHYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFLKD-DVRIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYTLPKGDEASINFLMTQALSHVAPLPFTYLVDQWRWKVLAGEISPSNYNSAWWRMRTLYQGVKPPVARNESDFDPGAKFHIVSNSPYIGYFVSLILQFQFHRALCNLVKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRPWPQTLFKLTGEREMSADPLLEYFAPLRKWLFNYRIKNNYTLGW 479
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Nematostella
Match: EDO28297 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6V7])

HSP 1 Score: 229.18 bits (583), Expect = 1.111e-68
Identity = 133/362 (36.74%), Postives = 186/362 (51.38%), Query Frame = 3 
Query:  969 NGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALK------MDSYIWSVYN----GTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +GPIPAH+ GN+W+Q W  I+++V+    +          S   +  +  KMF++A+ F+ SIGL  M   FW +S++ +   + + CH SA DF    D RI MCT+    D  TIHHEMGH EYF+AY   P  YRN AN GFHEAIGDTIAL+V TP+HL+ +GLL  +PK  E  I +LM  AL  VA LPF         +D  ++  Y+      I  + L  Y+  L L++Q                  +H                      ++C+L  + GPLH C  YQS +AG K  EML  G    W +T+  LTG +E+ +  LL++F PL  WL +     +  +GW
Sbjct:    4 SGPIPAHLLGNMWAQNWDGIYDMVQPYPDAT---PLDVTPSLIKQHYTPEKMFKLAQSFFVSIGLDPMPKSFWNKSMLRKPGNKSVVCHASAFDFLKD-DVRIKMCTRLKQEDLITIHHEMGHCEYFLAYKDQPYAYRNGANPGFHEAIGDTIALSVVTPKHLNSVGLLYTLPKGDEASINFLMTQALSHVAPLPFTFDFYRHDFIDITLFHRYDFIDMTFIDMTLLYRYFVSLILQFQ------------------FH---------------------RALCNLVKHTGPLHECSIYQSKEAGKKFKEMLAAGRSRPWPQTLFKLTGEREMSADPLLEYFAPLRKWLFNYRIKNNYTLGW 322
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772])

HSP 1 Score: 400.979 bits (1029), Expect = 6.695e-124
Identity = 227/597 (38.02%), Postives = 354/597 (59.30%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQ---DENISRNLVEVKSKIEYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIP-GRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E YPE  E+ ++E  AK  L + N       N Y   +++Y ++I   N + +    +          LKA+++    F  P V++++ KLS   R+    +E    N   + S +E  Y+  + C   G C P  +P +  +  + +DY++L   W  WR+  G  +R  + + VEL N  A  +G+SD  + +    +E   F+E +  L+  + PLY+ +H++VR  L+K Y P   +  GPIPAH+ GN+W+Q W+ I +         Y       A+  +  +  +  +MF+ ++ F+ S+GL  M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   ++D  T+HHEMGH++YF+ Y   P  +R+ AN GFHEAIGD +AL+V TP+HL  IGLL ++ ++ E DI +LM  AL+K+AFLPF   MD + W V++G IP ++ N+ WW+L LKYQG+ PPV R+E+DFD GAK+HI  +VPY+RYF+SFIIQFQF++++C+ + + GPLH CD YQS +AG  L +++K G    W E M I+TG  ++ +  L+++FEPL  WL+ +N+   + +GW
Sbjct:  545 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYN--TLLSNMETKYSVAEVCREDGRCHPL-DPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGA-MWRSLYETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIP-----YPGATQVDATPAMLAQGWNATRMFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1132

HSP 2 Score: 366.311 bits (939), Expect = 5.212e-111
Identity = 197/464 (42.46%), Postives = 283/464 (60.99%), Query Frame = 3 
Query:  654 EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            EP + D+    + Y KL   W  W N +G  ++ L+ + VEL N  ++ +GF+D  +      +E E F++ +  LY+ I PLY  LH+FVR  L+  Y  K+ +  GPIPAH+ GN+W+Q W NI++++           F  + +  +    VR+      MF ++EEF+ S+GL +M  EFWE S++ +   R + CH SA DF N  D+RI  CT   +    T+HHEMGHI+Y++ Y   P  +R  AN GFHEAIGD ++L+V TP+HLH I LL       E DI YL+  ALEK+AFLPF   +D + W V+NG  P  K N  WW L  K+QGI PP +RSE+ FD GAKYHI  + PYIRYF+SFI+QFQF+E +C+ + + GPLH CD Y+S +AG  L ++L+ G    W E ++   GT+E+ + SLLK+FEP+  WL+ +N  ++  +GW
Sbjct:   83 EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGA-DWRSWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIP---------FPNKPNLDVTDEMVRQGYNATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 534
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772])

HSP 1 Score: 400.979 bits (1029), Expect = 6.695e-124
Identity = 227/597 (38.02%), Postives = 354/597 (59.30%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQ---DENISRNLVEVKSKIEYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIP-GRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E YPE  E+ ++E  AK  L + N       N Y   +++Y ++I   N + +    +          LKA+++    F  P V++++ KLS   R+    +E    N   + S +E  Y+  + C   G C P  +P +  +  + +DY++L   W  WR+  G  +R  + + VEL N  A  +G+SD  + +    +E   F+E +  L+  + PLY+ +H++VR  L+K Y P   +  GPIPAH+ GN+W+Q W+ I +         Y       A+  +  +  +  +MF+ ++ F+ S+GL  M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   ++D  T+HHEMGH++YF+ Y   P  +R+ AN GFHEAIGD +AL+V TP+HL  IGLL ++ ++ E DI +LM  AL+K+AFLPF   MD + W V++G IP ++ N+ WW+L LKYQG+ PPV R+E+DFD GAK+HI  +VPY+RYF+SFIIQFQF++++C+ + + GPLH CD YQS +AG  L +++K G    W E M I+TG  ++ +  L+++FEPL  WL+ +N+   + +GW
Sbjct:  545 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYN--TLLSNMETKYSVAEVCREDGRCHPL-DPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGA-MWRSLYETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIP-----YPGATQVDATPAMLAQGWNATRMFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1132

HSP 2 Score: 366.311 bits (939), Expect = 5.212e-111
Identity = 197/464 (42.46%), Postives = 283/464 (60.99%), Query Frame = 3 
Query:  654 EPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            EP + D+    + Y KL   W  W N +G  ++ L+ + VEL N  ++ +GF+D  +      +E E F++ +  LY+ I PLY  LH+FVR  L+  Y  K+ +  GPIPAH+ GN+W+Q W NI++++           F  + +  +    VR+      MF ++EEF+ S+GL +M  EFWE S++ +   R + CH SA DF N  D+RI  CT   +    T+HHEMGHI+Y++ Y   P  +R  AN GFHEAIGD ++L+V TP+HLH I LL       E DI YL+  ALEK+AFLPF   +D + W V+NG  P  K N  WW L  K+QGI PP +RSE+ FD GAKYHI  + PYIRYF+SFI+QFQF+E +C+ + + GPLH CD Y+S +AG  L ++L+ G    W E ++   GT+E+ + SLLK+FEP+  WL+ +N  ++  +GW
Sbjct:   83 EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGA-DWRSWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIP---------FPNKPNLDVTDEMVRQGYNATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 534
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772])

HSP 1 Score: 402.519 bits (1033), Expect = 8.706e-124
Identity = 227/597 (38.02%), Postives = 354/597 (59.30%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQ---DENISRNLVEVKSKIEYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIP-GRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E YPE  E+ ++E  AK  L + N       N Y   +++Y ++I   N + +    +          LKA+++    F  P V++++ KLS   R+    +E    N +   S +E  Y+  + C   G C P  +P +  +  + +DY++L   W  WR+  G  +R  + + VEL N  A  +G+SD  + +    +E   F+E +  L+  + PLY+ +H++VR  L+K Y P   +  GPIPAH+ GN+W+Q W+ I +         Y       A+  +  +  +  +MF+ ++ F+ S+GL  M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   ++D  T+HHEMGH++YF+ Y   P  +R+ AN GFHEAIGD +AL+V TP+HL  IGLL ++ ++ E DI +LM  AL+K+AFLPF   MD + W V++G IP ++ N+ WW+L LKYQG+ PPV R+E+DFD GAK+HI  +VPY+RYF+SFIIQFQF++++C+ + + GPLH CD YQS +AG  L +++K G    W E M I+TG  ++ +  L+++FEPL  WL+ +N+   + +GW
Sbjct:  625 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYNTL--LSNMETKYSVAEVCREDGRCHPL-DPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGA-MWRSLYETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIP-----YPGATQVDATPAMLAQGWNATRMFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1212

HSP 2 Score: 367.466 bits (942), Expect = 6.569e-111
Identity = 207/522 (39.66%), Postives = 303/522 (58.05%), Query Frame = 3 
Query:  495 FSSPNVRKILDKLSKTVRSQDENISRNLV-EVKSKIEYIYNNGK----PCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
               P  +K+++K+     +      R     + S ++ IY+  K    P     L   EP + D+    + Y KL   W  W N +G  ++ L+ + VEL N  ++ +GF+D  +      +E E F++ +  LY+ I PLY  LH+FVR  L+  Y  K+ +  GPIPAH+ GN+W+Q W NI++++           F  + +  +    VR+      MF ++EEF+ S+GL +M  EFWE S++ +   R + CH SA DF N  D+RI  CT   +    T+HHEMGHI+Y++ Y   P  +R  AN GFHEAIGD ++L+V TP+HLH I LL       E DI YL+  ALEK+AFLPF   +D + W V+NG  P  K N  WW L  K+QGI PP +RSE+ FD GAKYHI  + PYIRYF+SFI+QFQF+E +C+ + + GPLH CD Y+S +AG  L ++L+ G    W E ++   GT+E+ + SLLK+FEP+  WL+ +N  ++  +GW
Sbjct:  108 LPDPKDKKLMEKIKSLGAANLPQAEREKYNTILSTMDSIYSTAKVYPQPNVSWSL---EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGA-DWRSWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIP---------FPNKPNLDVTDEMVRQGYNATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 614
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772])

HSP 1 Score: 402.134 bits (1032), Expect = 1.068e-123
Identity = 227/597 (38.02%), Postives = 354/597 (59.30%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQ---DENISRNLVEVKSKIEYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIP-GRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E YPE  E+ ++E  AK  L + N       N Y   +++Y ++I   N + +    +          LKA+++    F  P V++++ KLS   R+    +E    N   + S +E  Y+  + C   G C P  +P +  +  + +DY++L   W  WR+  G  +R  + + VEL N  A  +G+SD  + +    +E   F+E +  L+  + PLY+ +H++VR  L+K Y P   +  GPIPAH+ GN+W+Q W+ I +         Y       A+  +  +  +  +MF+ ++ F+ S+GL  M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   ++D  T+HHEMGH++YF+ Y   P  +R+ AN GFHEAIGD +AL+V TP+HL  IGLL ++ ++ E DI +LM  AL+K+AFLPF   MD + W V++G IP ++ N+ WW+L LKYQG+ PPV R+E+DFD GAK+HI  +VPY+RYF+SFIIQFQF++++C+ + + GPLH CD YQS +AG  L +++K G    W E M I+TG  ++ +  L+++FEPL  WL+ +N+   + +GW
Sbjct:  623 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYN--TLLSNMETKYSVAEVCREDGRCHPL-DPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGA-MWRSLYETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIP-----YPGATQVDATPAMLAQGWNATRMFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1210

HSP 2 Score: 367.081 bits (941), Expect = 7.915e-111
Identity = 207/522 (39.66%), Postives = 303/522 (58.05%), Query Frame = 3 
Query:  495 FSSPNVRKILDKLSKTVRSQDENISRNLV-EVKSKIEYIYNNGK----PCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
               P  +K+++K+     +      R     + S ++ IY+  K    P     L   EP + D+    + Y KL   W  W N +G  ++ L+ + VEL N  ++ +GF+D  +      +E E F++ +  LY+ I PLY  LH+FVR  L+  Y  K+ +  GPIPAH+ GN+W+Q W NI++++           F  + +  +    VR+      MF ++EEF+ S+GL +M  EFWE S++ +   R + CH SA DF N  D+RI  CT   +    T+HHEMGHI+Y++ Y   P  +R  AN GFHEAIGD ++L+V TP+HLH I LL       E DI YL+  ALEK+AFLPF   +D + W V+NG  P  K N  WW L  K+QGI PP +RSE+ FD GAKYHI  + PYIRYF+SFI+QFQF+E +C+ + + GPLH CD Y+S +AG  L ++L+ G    W E ++   GT+E+ + SLLK+FEP+  WL+ +N  ++  +GW
Sbjct:  106 LPDPKDKKLMEKIKSLGAANLPQAEREKYNTILSTMDSIYSTAKVYPQPNVSWSL---EPELTDIMATSRSYKKLLFAWDGWHNASGVPLKKLYPEFVELSNKASQADGFADTGA-DWRSWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIP---------FPNKPNLDVTDEMVRQGYNATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 612
[Close]
BLAST of Angiotensin-converting enzyme vs. Ensembl Medaka
Match: ace (angiotensin I converting enzyme [Source:NCBI gene;Acc:101172772])

HSP 1 Score: 402.134 bits (1032), Expect = 1.582e-123
Identity = 227/597 (38.02%), Postives = 354/597 (59.30%), Query Frame = 3 
Query:  261 EDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQ---DENISRNLVEVKSKIEYIYNNGKPCF--GICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYY-PGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKL--EKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIP-GRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            E YPE  E+ ++E  AK  L + N       N Y   +++Y ++I   N + +    +          LKA+++    F  P V++++ KLS   R+    +E    N   + S +E  Y+  + C   G C P  +P +  +  + +DY++L   W  WR+  G  +R  + + VEL N  A  +G+SD  + +    +E   F+E +  L+  + PLY+ +H++VR  L+K Y P   +  GPIPAH+ GN+W+Q W+ I +         Y       A+  +  +  +  +MF+ ++ F+ S+GL  M  EFWE+S++E+   GR + CH SA DF N  D+RI  CT   ++D  T+HHEMGH++YF+ Y   P  +R+ AN GFHEAIGD +AL+V TP+HL  IGLL ++ ++ E DI +LM  AL+K+AFLPF   MD + W V++G IP ++ N+ WW+L LKYQG+ PPV R+E+DFD GAK+HI  +VPY+RYF+SFIIQFQF++++C+ + + GPLH CD YQS +AG  L +++K G    W E M I+TG  ++ +  L+++FEPL  WL+ +N+   + +GW
Sbjct:  649 EGYPEDIEKNTDELDAKRLLDEYNTTAEEVWNAYTEASWKYNTDITDANKQAMLNRSLEMSAHTLKYGLKAREYDTTDFQDPLVKRVIAKLSDIERAALPPEELEEYN--TLLSNMETKYSVAEVCREDGRCHPL-DPDLQKIMAESRDYNELLFAWKGWRDAAGKVLRQDYERYVELANKAAVLDGYSDNGA-MWRSLYETPTFEEDLESLWMELQPLYQNVHAYVRRALYKKYGPQHINLKGPIPAHLLGNMWAQTWSGIMDFAIP-----YPGATQVDATPAMLAQGWNATRMFQESDRFFTSLGLLPMPEEFWEKSMLEKPSDGRQVVCHASAWDFYNRKDFRIKQCTVVTMDDLITVHHEMGHVQYFLQYKDQPVSFRDGANPGFHEAIGDVLALSVSTPKHLKSIGLLDKVEENYESDINFLMSMALDKIAFLPFGYLMDQWRWKVFDGRIPPNEYNKEWWNLRLKYQGLCPPVARTEEDFDPGAKFHIPANVPYVRYFVSFIIQFQFHKALCEAANHNGPLHTCDIYQSKEAGKLLSDVMKLGSSKPWPEAMAIITGQSKMSAQPLMQYFEPLIQWLQRENQMNGDVIGW 1236

HSP 2 Score: 369.777 bits (948), Expect = 1.311e-111
Identity = 198/459 (43.14%), Postives = 284/459 (61.87%), Query Frame = 3 
Query:  669 DLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKF-DKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRK------MFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++  K + Y+KL   W AWRN +G  ++ L+ + VEL N  +R +GF+D  +      +E E F++ +  LY+ I PLY  LH+FVR  L+  Y  K+ +  GPIPAH+ GN+W+Q W NI++++           F  + +  +    VR+      MF ++EEF+ S+GL +M  EFWE S++ +   R + CH SA DF N  D+RI  CT   +    T+HHEMGHI+Y++ Y   P  +R  AN GFHEAIGD ++L+V TP+HLH I LL       E DI YL+  ALEK+AFLPF   +D + W V+NG  P  K N  WW L  K+QGI PP +RSE+ FD GAKYHI  + PYIRYF+SFI+QFQF+E +C+ + + GPLH CD Y+S +AG  L ++L+ G    W E ++   GT+E+ + SLLK+FEP+  WL+ +N  ++  +GW
Sbjct:  192 EIMAKSRSYEKLLFVWEAWRNESGVPLKQLYTRFVELSNKASRADGFADTGA-DWRSWYESETFEQDIDNLYKTIEPLYLHLHAFVRRKLYNQYGSKYINLKGPIPAHLLGNMWAQTWNNIYDLMIP---------FPNKPNLDVTDEMVRQGYNATHMFRVSEEFFTSLGLLEMPTEFWEGSMIVKPDDREVVCHASAWDFYNRKDFRIKQCTTVTMEQLFTVHHEMGHIQYYLQYKDQPVGFRRGANPGFHEAIGDVLSLSVSTPKHLHTINLLESAASDTETDINYLLKMALEKIAFLPFGYLIDLWRWGVFNGRTPPEKYNSEWWYLRTKFQGICPPTKRSEEHFDPGAKYHIPGNTPYIRYFVSFILQFQFHEKLCEAAKHTGPLHTCDIYRSAEAGEILRKVLQAGSSKPWPEVLQEAIGTREMNANSLLKYFEPVIKWLEEQN--VNETLGW 638
[Close]
BLAST of Angiotensin-converting enzyme vs. Planmine SMEST
Match: SMESG000005698.1 (SMESG000005698.1)

HSP 1 Score: 1270.37 bits (3286), Expect = 0.000e+0
Identity = 630/630 (100.00%), Postives = 630/630 (100.00%), Query Frame = 3 
Query:  135 MYLIILFVAVDFIYCKHISYLINSHNIYQKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            MYLIILFVAVDFIYCKHISYLINSHNIYQKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW
Sbjct:    1 MYLIILFVAVDFIYCKHISYLINSHNIYQKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 630
[Close]
BLAST of Angiotensin-converting enzyme vs. Planmine SMEST
Match: SMESG000005698.1 (SMESG000005698.1)

HSP 1 Score: 1211.05 bits (3132), Expect = 0.000e+0
Identity = 601/601 (100.00%), Postives = 601/601 (100.00%), Query Frame = 3 
Query:  222 KQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            KQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW
Sbjct:   10 KQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 610
[Close]
BLAST of Angiotensin-converting enzyme vs. Planmine SMEST
Match: SMESG000005704.1 (SMESG000005704.1)

HSP 1 Score: 1204.12 bits (3114), Expect = 0.000e+0
Identity = 597/605 (98.68%), Postives = 603/605 (99.67%), Query Frame = 3 
Query:  210 NIYQKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++ +KQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQ+WTNIFEIVKKCMKSNYQN+FHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQG+KNNWRETMK LTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW
Sbjct:   22 DLNKKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQKWTNIFEIVKKCMKSNYQNNFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGKKNNWRETMKTLTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 626
[Close]
BLAST of Angiotensin-converting enzyme vs. Planmine SMEST
Match: SMESG000005710.1 (SMESG000005710.1)

HSP 1 Score: 801.586 bits (2069), Expect = 0.000e+0
Identity = 373/602 (61.96%), Postives = 489/602 (81.23%), Query Frame = 3 
Query:  219 QKQIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            +  +FDSY+++T+LE YP VC+EY++E CAK W  K+NEI+IRN NR+AN++++Y ++INK NLEL K+FQ I  K+G  ++ K+KKF WK F SP +R+    ++ ++R+++E++   L+ + + I YIYNN KPCF  CL  GE  II LFK EKDY+KL GYW AWRNVTG +I+ LF+++++LEN+G+RENG  D A++ L  DFE+++FK T ++LY  ILPLYKELH +VRYCL K+YPGKFDK+GPIPAHIFGNVW+QQWTNIF I++ C +     ++ ++A+  L K+ V +MF +AEEFY SIG+FKMT+EFWERS++ +   ++++CHGSAHDF+NGVD+RI MCT+K++ DFTTIHHEMGHIEY+MAYS LPT +R SANSGFHEAIGDTIALAVKTPEHLHKIGL+  +P SK FDI+YLM +ALEKVAFLPFAL MDSYIW +YNG++P S++N++WWDL  +YQG+ PPV+R+E DFD G+KYHI+F V YIRYF+SF+IQFQFYESMC++SGYKGPLHRC+FYQS +AG KL+EML +G+  NWRETMKILTG  EIKS SLLKFF+PL+ WLK  N+ L+  +GW
Sbjct:   40 EPSVFDSYYHMTDLEGYPNVCDEYASEKCAKLWFDKINEISIRNRNRFANIHFKYSTDINKKNLELKKRFQRIGSKIGLKLKRKSKKFHWKSFKSPELRRKFRLITASIRNENESLVHELIHINNDISYIYNNAKPCFNKCLEVGESGIIKLFKTEKDYEKLAGYWTAWRNVTGQKIKKLFLRRMQLENIGSRENGHEDAATYGLSFDFEDDDFKSTALKLYGAILPLYKELHGYVRYCLNKFYPGKFDKSGPIPAHIFGNVWAQQWTNIFPIIRDCGQKLSAENYQDEATENLSKMPVEQMFTIAEEFYESIGMFKMTDEFWERSMLSKPQDKVVNCHGSAHDFSNGVDFRIKMCTEKNIVDFTTIHHEMGHIEYYMAYSHLPTIFRGSANSGFHEAIGDTIALAVKTPEHLHKIGLISRVPDSKGFDIDYLMATALEKVAFLPFALSMDSYIWGLYNGSVPLSEVNKHWWDLRYRYQGLMPPVKRTEDDFDPGSKYHISFGVSYIRYFVSFLIQFQFYESMCNISGYKGPLHRCNFYQSKEAGLKLMEMLSKGKSQNWRETMKILTGATEIKSESLLKFFDPLYKWLKFTNKKLNIPIGW 641
[Close]
BLAST of Angiotensin-converting enzyme vs. Planmine SMEST
Match: SMESG000005712.1 (SMESG000005712.1)

HSP 1 Score: 640.958 bits (1652), Expect = 0.000e+0
Identity = 299/602 (49.67%), Postives = 440/602 (73.09%), Query Frame = 3 
Query:  225 QIFDSYHNLTELEDYPEVCEEYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQIIYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVEVKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNVTGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLYEGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFEIVKKCMKSNYQNDFH--EQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEFWERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMGHIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEIPKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWWDLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPXXXXXXXXXXXXXXXESMCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKEIKSGSLLKFFEPLHVWLKHKNRDLHNRVGW 2024
            ++FDS++ LT LE YP+ C    +E CA++WL+KVNEI IRN+NR AN+ YRY +NI   NL LL +F+I   K  N++   AK F W++F S  +R++ + ++ +V+S D  + + ++++K++IE+IYN  +PC+  CL AGE  I++LF  EK+YD L GYW+ WR  TG +IR+L++ +  LE   A+ENG  ++ASF +FEDF+EENF ET+++L++ ++P+YK+LH++VRYCL +YYP +F+K GPIPAHI G+VW+Q W NIF I+K+C ++N  N FH   + + KL K+SV ++F+  E  Y  +G+++MTNEFWERS+  +   R++DCH S+ DF+NG D+R+ MC+KK ++ F+ IHHEMGHI+YFMAY  LP  YR SANS F E IGDT+AL++KT   L KIGLL  IPK+ + +I+YLM  ALE V F+PFA+    ++ S+YNG++P+S++N YWW L   YQGIKPP+ER+E++FD G+KYHIAF +PYIR+F+S +++FQF+ES+C+++    PLH C  YQS   G+ L+E++K G++  WRE +KI+   ++I+S SLL+FF PL  WL   N+ L+  VGW
Sbjct:   37 EVFDSFYWLTPLEYYPDSC---LSETCAENWLVKVNEIMIRNENRIANVYYRYATNITSDNLMLLNQFRITKVKYENNLISIAKGFPWQQFYSKKMREMFEIITTSVKSVDPEVFKRIIKIKNRIEHIYNKARPCYKTCLSAGESGIVNLFNTEKNYDTLLGYWIVWRKETGVQIRDLYIDRFNLEIQAAKENGIQNIASFKMFEDFQEENFLETLMKLFDNVMPIYKQLHAYVRYCLAEYYPDRFNKTGPIPAHILGDVWAQNWINIFPIIKQCSRNN--NPFHVFHEVNFKLSKMSVNQIFKTVESNYVGMGMYQMTNEFWERSLFTKPNDRIVDCHSSSEDFSNGFDFRVKMCSKKTVSYFSAIHHEMGHIQYFMAYQHLPILYRASANSAFQEIIGDTMALSMKTLSSLEKIGLLSNIPKTFDLEIDYLMLLALENVPFVPFAMINSVFVNSLYNGSVPTSRMNSYWWKLVHTYQGIKPPIERTEENFDPGSKYHIAFGIPYIRHFVSSLLKFQFFESLCEMNKGIEPLHFCTLYQSKNVGSLLIEIMKNGQRKPWREIIKIINRNEDIQSDSLLRFFAPLTQWLIKTNKMLNIHVGW 633
The following BLAST results are available for this feature:
BLAST of Angiotensin-converting enzyme vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ACE4.172e-12539.22angiotensin I converting enzyme [Source:HGNC Symbo... [more]
AC113554.15.721e-12539.22novel protein[more]
ACE1.449e-12138.02angiotensin I converting enzyme [Source:HGNC Symbo... [more]
ACE3.870e-12138.02angiotensin I converting enzyme [Source:HGNC Symbo... [more]
ACE8.018e-10634.45angiotensin I converting enzyme [Source:HGNC Symbo... [more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
acn-19.025e-4324.23Inactive angiotensin-converting enzyme-related pro... [more]
acn-19.025e-4324.23Inactive angiotensin-converting enzyme-related pro... [more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ance1.548e-11235.98gene:FBgn0012037 transcript:FBtr0080553[more]
Ance1.548e-11235.98gene:FBgn0012037 transcript:FBtr0343667[more]
Ance1.548e-11235.98gene:FBgn0012037 transcript:FBtr0080552[more]
Ance-31.288e-9536.77gene:FBgn0032536 transcript:FBtr0343641[more]
Ance-31.288e-9536.77gene:FBgn0032536 transcript:FBtr0100327[more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ace1.070e-12839.50angiotensin I converting enzyme (peptidyl-dipeptid... [more]
ace26.569e-9532.44angiotensin I converting enzyme 2 [Source:ZFIN;Acc... [more]
ace21.669e-9432.44angiotensin I converting enzyme 2 [Source:ZFIN;Acc... [more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ace7.014e-13742.13angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace1.913e-13439.87angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace4.444e-13439.87angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace7.125e-13440.07angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace7.554e-13440.07angiotensin I converting enzyme [Source:NCBI gene;... [more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ace7.603e-12538.25angiotensin I converting enzyme (peptidyl-dipeptid... [more]
Ace2.437e-12237.10angiotensin I converting enzyme (peptidyl-dipeptid... [more]
Ace2.289e-12037.10angiotensin I converting enzyme (peptidyl-dipeptid... [more]
Ace31.180e-11235.87angiotensin I converting enzyme (peptidyl-dipeptid... [more]
Ace23.097e-9132.52angiotensin I converting enzyme (peptidyl-dipeptid... [more]
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BLAST of Angiotensin-converting enzyme vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q10751|ACE_CHICK9.356e-12539.36Angiotensin-converting enzyme (Fragment) OS=Gallus... [more]
sp|P12821|ACE_HUMAN1.858e-12038.02Angiotensin-converting enzyme OS=Homo sapiens OX=9... [more]
sp|Q9GLN7|ACE_PANTR5.971e-12038.29Angiotensin-converting enzyme OS=Pan troglodytes O... [more]
sp|Q50JE5|ACE_MESAU7.979e-12037.99Angiotensin-converting enzyme OS=Mesocricetus aura... [more]
sp|P09470|ACE_MOUSE1.601e-11937.10Angiotensin-converting enzyme OS=Mus musculus OX=1... [more]
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BLAST of Angiotensin-converting enzyme vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
I1ZIB10.000e+050.51Angiotensin-converting enzyme (Fragment) OS=Schmid... [more]
A0A1S3GZX97.365e-14740.79Angiotensin-converting enzyme OS=Lingula unguis OX... [more]
A0A4Y2HGM01.466e-14141.51Angiotensin-converting enzyme OS=Araneus ventricos... [more]
C3Z9J81.347e-13741.37Angiotensin-converting enzyme OS=Branchiostoma flo... [more]
A0A2L2Y2544.357e-13741.67Angiotensin-converting enzyme (Fragment) OS=Parast... [more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ace1.151e-13640.54angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace23.811e-9431.76angiotensin I converting enzyme 2 [Source:NCBI gen... [more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ace1.256e-12837.33angiotensin I converting enzyme (peptidyl-dipeptid... [more]
ENSPMAT00000004373.18.161e-7838.11pep scaffold:Pmarinus_7.0:GL477858:25443:42821:1 g... [more]
ENSPMAT00000004370.11.906e-6338.36pep scaffold:Pmarinus_7.0:GL477858:22090:39821:1 g... [more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Angiotensin-converting enzyme vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO379475.723e-12438.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO356596.699e-12341.75Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO296885.542e-12042.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO340638.500e-12042.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO282971.111e-6836.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Angiotensin-converting enzyme vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ace6.695e-12438.02angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace6.695e-12438.02angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace8.706e-12438.02angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace1.068e-12338.02angiotensin I converting enzyme [Source:NCBI gene;... [more]
ace1.582e-12338.02angiotensin I converting enzyme [Source:NCBI gene;... [more]
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BLAST of Angiotensin-converting enzyme vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000005698.10.000e+0100.00SMESG000005698.1[more]
SMESG000005698.10.000e+0100.00SMESG000005698.1[more]
SMESG000005704.10.000e+098.68SMESG000005704.1[more]
SMESG000005710.10.000e+061.96SMESG000005710.1[more]
SMESG000005712.10.000e+049.67SMESG000005712.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014565 ID=SMED30014565|Name=Angiotensin-converting enzyme|organism=Schmidtea mediterranea sexual|type=transcript|length=2360bp
TTTCAACTGAAATTTGTGGATTGGTCTAATCAAGTCATTATTATGCTTTG
GTGCTAATTTGTAGCTAATTTGCATGCGTACAATCTTAAAAATCGATTTG
GTAAGTTTGTAGATTGATATCATTCAGTAATTAAATGTACTTGATTATTT
TATTTGTTGCTGTGGATTTTATTTATTGCAAACATATTTCCTATTTAATA
AATTCGCATAATATCTATCAGAAACAAATATTCGACAGCTACCATAATTT
GACAGAGCTGGAAGATTACCCTGAAGTCTGCGAGGAGTATTCAAACGAAA
ATTGTGCCAAGTCTTGGTTAATAAAAGTCAATGAAATAACAATAAGAAAT
GATAATCGCTATGCCAATCTTAATTATCGTTACGGATCAAATATCAACAA
AACAAATTTGGAATTATTGAAAAAATTTCAGATAATCTATGGAAAACTGG
GAAATTCAATCCAGCTGAAAGCCAAAAAATTTCAATGGAAAAGATTTTCC
TCACCAAATGTCAGAAAAATCTTGGACAAACTTTCCAAAACCGTACGAAG
TCAGGATGAAAACATTTCGCGAAATTTGGTTGAAGTTAAAAGCAAAATTG
AATACATTTACAATAATGGAAAGCCGTGTTTTGGAATATGTCTGCCAGCC
GGGGAGCCCGCAATTATTGATTTATTTAAGAAGGAAAAGGATTATGATAA
ATTAACCGGATATTGGGTGGCATGGAGAAATGTGACGGGGGCAAGAATTA
GAAATTTGTTTGTGAAGAAAGTTGAACTGGAAAATCTTGGAGCTCGTGAA
AACGGATTTAGTGATTTGGCTTCGTTTATTCTATTTGAGGATTTCGAGGA
GGAAAACTTCAAAGAGACAGTGATACAATTGTATGAGGGCATTCTGCCGC
TGTATAAAGAATTGCATTCGTTTGTGAGATATTGTCTTTGGAAATATTAT
CCCGGGAAATTCGATAAAAATGGACCAATTCCGGCCCATATTTTCGGAAA
TGTTTGGTCCCAACAATGGACCAATATTTTTGAGATAGTAAAAAAATGTA
TGAAAAGTAATTATCAAAATGATTTTCACGAACAAGCAAGCGCGAAATTG
GAGAAATTATCGGTGAGAAAAATGTTTGAAATGGCCGAAGAATTTTACAA
TTCTATTGGATTGTTCAAAATGACAAATGAATTCTGGGAAAGAAGCGTTG
TAGAACAAATTCCAGGACGCCTGATTGACTGTCATGGATCGGCTCATGAT
TTTGCAAACGGTGTCGATTATAGAATTTTAATGTGTACGAAGAAAGATTT
AAATGATTTCACAACTATTCATCATGAAATGGGTCACATCGAATATTTCA
TGGCTTACAGCAAATTGCCTACGTTTTATCGTAATTCAGCGAATTCTGGA
TTCCACGAAGCTATTGGAGACACAATCGCATTAGCTGTGAAAACGCCAGA
ACACCTTCACAAAATTGGTCTGTTGCCAGAGATTCCAAAATCCAAAGAAT
TTGACATTGAATATTTGATGGGTTCCGCTTTAGAAAAAGTAGCATTCTTA
CCATTTGCGTTAAAGATGGATAGTTATATATGGAGTGTATATAATGGAAC
GATTCCTTCTTCAAAGCTTAATGAATATTGGTGGGATCTATCATTGAAGT
ATCAAGGAATCAAGCCACCAGTTGAGAGATCAGAGAAAGATTTTGATGCG
GGTGCAAAATATCACATTGCATTTAGTGTTCCTTATATTCGATATTTTAT
AAGTTTTATAATTCAATTTCAATTTTATGAATCAATGTGTGATTTGAGCG
GTTACAAAGGTCCCTTGCATAGATGTGACTTTTATCAATCACATAAAGCA
GGAAACAAACTTTTGGAAATGTTAAAGCAAGGGGAAAAGAATAACTGGAG
AGAAACAATGAAAATTCTAACAGGAACAAAAGAAATCAAATCTGGATCCC
TTTTGAAATTTTTCGAGCCGCTTCATGTTTGGTTGAAACATAAAAACAGA
GATTTACATAATCGTGTTGGCTGGTAAGCAAACAACATTATTGAACGTCA
AATTGTTTGTATTAAACGTTTGTTGTAAATCAATTTGTTTTTAGAATTCA
GTTGACAATTTTTCTTTTAAATATAACCTACACAATGTATATTTTTATAT
TTTAGGTTCTTAATTTAAAACAATGCTACTCAAACAAATATCCCTGCACC
GCACAATTTTGAAAAAAATATTACTGTACAAAAAATCAAAGCAAATTTGA
ATCTCACGCTGTTGCAAAGTTCGTTGAAATAAACTGTTATTTTCATGAAA
TGGAATTTGACAAATTTTGAAATAATTTTTATTATTAATAAAATAAATAA
AATTTAATAG
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protein sequence of SMED30014565-orf-1

>SMED30014565-orf-1 ID=SMED30014565-orf-1|Name=SMED30014565-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=631bp
MYLIILFVAVDFIYCKHISYLINSHNIYQKQIFDSYHNLTELEDYPEVCE
EYSNENCAKSWLIKVNEITIRNDNRYANLNYRYGSNINKTNLELLKKFQI
IYGKLGNSIQLKAKKFQWKRFSSPNVRKILDKLSKTVRSQDENISRNLVE
VKSKIEYIYNNGKPCFGICLPAGEPAIIDLFKKEKDYDKLTGYWVAWRNV
TGARIRNLFVKKVELENLGARENGFSDLASFILFEDFEEENFKETVIQLY
EGILPLYKELHSFVRYCLWKYYPGKFDKNGPIPAHIFGNVWSQQWTNIFE
IVKKCMKSNYQNDFHEQASAKLEKLSVRKMFEMAEEFYNSIGLFKMTNEF
WERSVVEQIPGRLIDCHGSAHDFANGVDYRILMCTKKDLNDFTTIHHEMG
HIEYFMAYSKLPTFYRNSANSGFHEAIGDTIALAVKTPEHLHKIGLLPEI
PKSKEFDIEYLMGSALEKVAFLPFALKMDSYIWSVYNGTIPSSKLNEYWW
DLSLKYQGIKPPVERSEKDFDAGAKYHIAFSVPYIRYFISFIIQFQFYES
MCDLSGYKGPLHRCDFYQSHKAGNKLLEMLKQGEKNNWRETMKILTGTKE
IKSGSLLKFFEPLHVWLKHKNRDLHNRVGW*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000035Category 3 cell
PLANA:0002032epidermal cell
PLANA:0002056medial muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR001548Peptidase_M2
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0008237metallopeptidase activity
GO:0008241peptidyl-dipeptidase activity
GO:0004180carboxypeptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001548Peptidase M2, peptidyl-dipeptidase APRINTSPR00791PEPDIPTASEAcoord: 360..385
score: 55.45
coord: 246..273
score: 37.8
coord: 496..523
score: 59.23
coord: 420..440
score: 68.65
coord: 392..408
score: 64.22
coord: 461..486
score: 46.79
coord: 280..301
score: 55.68
coord: 524..552
score: 68.97
IPR001548Peptidase M2, peptidyl-dipeptidase APFAMPF01401Peptidase_M2coord: 53..630
e-value: 2.5E-182
score: 607.5
IPR001548Peptidase M2, peptidyl-dipeptidase APANTHERPTHR10514ANGIOTENSIN-CONVERTING ENZYMEcoord: 37..630
IPR001548Peptidase M2, peptidyl-dipeptidase ACDDcd06461M2_ACEcoord: 61..621
e-value: 0.0
score: 709.377
NoneNo IPR availableGENE3DG3DSA:1.10.1370.30coord: 369..623
e-value: 4.7E-6
score: 27.6
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..15
score: 0.535
NoneNo IPR availableSUPERFAMILYSSF55486Metalloproteases ("zincins"), catalytic domaincoord: 58..630