4-hydroxyphenylpyruvate dioxygenase

Overview
Name4-hydroxyphenylpyruvate dioxygenase
Smed IDSMED30014546
Length (bp)1302
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of 4-hydroxyphenylpyruvate dioxygenase (SMED30014546) t-SNE clustered cells

Violin plots show distribution of expression levels for 4-hydroxyphenylpyruvate dioxygenase (SMED30014546) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 4-hydroxyphenylpyruvate dioxygenase (SMED30014546) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 4-hydroxyphenylpyruvate dioxygenase (SMED30014546) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014546

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pigment cellSMED30014546h1SMcG0006430 SmedASXL_007979SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
cephalic gangliaSMED30014546h1SMcG0006430 dd_Smed_v4_1114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014546h1SMcG0006430 dd_Smed_v4_1114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014546h1SMcG0006430 Contig39300newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014546h1SMcG0006430 Contig39300uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
tail regionSMED30014546h1SMcG0006430 dd_Smed_v6_1114_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
pigment cellSMED30014546h1SMcG0006430 dd_Smed_v6_1114_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014546h1SMcG0006430 dd_Smed_v6_1114_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Human
Match: HPD (4-hydroxyphenylpyruvate dioxygenase [Source:HGNC Symbol;Acc:HGNC:5147])

HSP 1 Score: 493.041 bits (1268), Expect = 1.203e-173
Identity = 232/381 (60.89%), Postives = 289/381 (75.85%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            TTY+DKG K E G+F  F+ +TF VGNAKQA S YC+++GF   AY+GLETG+REV +HV+KQ  I+F  SS L P   KE+G+HL  HGD VKDIAFEVED D I  KA E+GA ++++ W E D+ G VKFA ++T+ DTTHT +++  Y G +LP Y      DP+        L  IDHIVGNQPD +M +  EWY K LQFHRFWSVDD+Q+HTEYS+LRSIV+ NY+E++K+PINEPA GK+KSQIQEYVDY G  GVQHIA+ T DII AI+ L+ RGL+FL  P TYY  LR++L++AKIKV E++D LE+L IL+D+D+ GYLLQIFTK +QDRPT+FLEVIQRHNH GFGAGNF SLF+A E +Q  RGNL
Sbjct:    2 TTYSDKGAKPERGRFLHFHSVTFWVGNAKQATSFYCSKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWN-KEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQNLRGNL 381
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Human
Match: HPD (4-hydroxyphenylpyruvate dioxygenase [Source:HGNC Symbol;Acc:HGNC:5147])

HSP 1 Score: 442.195 bits (1136), Expect = 3.225e-154
Identity = 209/343 (60.93%), Postives = 260/343 (75.80%), Query Frame = 1 
Query:  178 LGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            +GF   AY+GLETG+REV +HV+KQ  I+F  SS L P   KE+G+HL  HGD VKDIAFEVED D I  KA E+GA ++++ W E D+ G VKFA ++T+ DTTHT +++  Y G +LP Y      DP+        L  IDHIVGNQPD +M +  EWY K LQFHRFWSVDD+Q+HTEYS+LRSIV+ NY+E++K+PINEPA GK+KSQIQEYVDY G  GVQHIA+ T DII AI+ L+ RGL+FL  P TYY  LR++L++AKIKV E++D LE+L IL+D+D+ GYLLQIFTK +QDRPT+FLEVIQRHNH GFGAGNF SLF+A E +Q  RGNL
Sbjct:    1 MGFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWN-KEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQNLRGNL 342
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Human
Match: HPDL (4-hydroxyphenylpyruvate dioxygenase like [Source:HGNC Symbol;Acc:HGNC:28242])

HSP 1 Score: 110.538 bits (275), Expect = 3.317e-26
Identity = 77/303 (25.41%), Postives = 144/303 (47.52%), Query Frame = 1 
Query:  337 AVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDT-THTFIDRSQYKGVYLPNYRLINDEDPINKIFESPG-LNFIDHIVGNQPDDQMNNIVEWYEKTLQF-HRFWSV-DDSQIHTEYSA---LRSIVITNYD-------ETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRK--QLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEER 1197
            +  ++ F+V D  A   +    G +V        D  G   +A + +     + T ++R+ Y+G +LP +R ++           PG ++ +DH+           ++ W+   L F H   S  +D ++  E +A   L  + +T           T+ L  + P A  R+ Q+++++  +   G+QH+ + T +I++A + +   G +FL  P  YY    K  Q+ +A      +   L +  IL+D D   +LLQ+FTK++    T FLE+IQR    GFG GN ++L+++++ +Q  R
Sbjct:   77 SATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPAGILSLTLLERAGYRGPFLPGFRPVSSAP-------GPGWVSRVDHLTLACTPGSSPTLLRWFHDCLGFCHLPLSPGEDPELGLEMTAGFGLGGLRLTALQAQPGSIVPTLVLAESLPGATTRQDQVEQFLARHKGPGLQHVGLYTPNIVEATEGVATAGGQFLAPPGAYYQQPGKERQIRAAG----HEPHLLARQGILLDGDKGKFLLQVFTKSLFTEDTFFLELIQRQGATGFGQGNIRALWQSVQ-EQSAR 367
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Celegans
Match: hpd-1 (4-hydroxyphenylpyruvate dioxygenase [Source:UniProtKB/Swiss-Prot;Acc:Q22633])

HSP 1 Score: 472.626 bits (1215), Expect = 4.775e-166
Identity = 220/382 (57.59%), Postives = 286/382 (74.87%), Query Frame = 1 
Query:   67 TYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRK--SQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T  DKG K + G F +F  + F+VGNAKQAA  YCA  GF  FAY+GLETG+R  A H ++Q+ I+F F S LLP+   E+G HL  HGD VKD+ FEVEDLD+I   A   GA +V DI  ESD +G++++A ++T+ +T HT ++R  Y+G +LP ++         K     GLNF+DH VGNQPD QM++ V+WYEK L+FHRFWSVDDS IHTEYSALRSIV+TN++ET+K+PINEPA   +K  SQIQEYVDYYG  GVQHIA+NT+DII AI+ L+ RG +FL  P +YY  L+++L ++ + V ED+D+L+KL IL+DFD+NGYLLQIF+K  QDRPT+FLE+IQR NH GFGAGNFK+LFE+IE++Q +RGNL
Sbjct:    2 TTFDKGAKPDIGTFVAFDHVRFVVGNAKQAAYWYCANFGFEPFAYKGLETGSRITAQHAIRQDKIVFIFESALLPDN-SELGNHLVQHGDGVKDVCFEVEDLDSIIAHAKAAGATIVHDITEESDADGSIRYATLRTYGETDHTLLERKNYRGAFLPGFKAHPMPATFFKTLPRVGLNFLDHCVGNQPDLQMDSAVQWYEKVLKFHRFWSVDDSMIHTEYSALRSIVVTNFEETIKMPINEPATSDKKAISQIQEYVDYYGGSGVQHIALNTSDIITAIEALRARGCEFLSIPSSYYDNLKERLAASSMVVKEDMDRLQKLHILVDFDENGYLLQIFSKPCQDRPTLFLEIIQRQNHEGFGAGNFKALFESIELEQTKRGNL 382
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Celegans
Match: C31H2.4 (pep chromosome:WBcel235:X:5155093:5159667:-1 gene:WBGene00016294.1 transcript:C31H2.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C31H2.4)

HSP 1 Score: 277.33 bits (708), Expect = 6.335e-90
Identity = 145/371 (39.08%), Postives = 230/371 (61.99%), Query Frame = 1 
Query:  100 GKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKT-FYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKR-KSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            G   + + I F+V NA Q+A  YC+  GF +FA + +   +  +A        II +++S  +        + L  HGD +KD++F V++LDA+    VE    V++     S ++G V+ A + +   D THT  +  ++KG +LP +  I++ +    I + P +  +DH+V N P  +M    +WY KT++  RFWSVDD    +E+SA+ + ++ N D TV++ + E   G++ KSQI+E+++Y+G  GVQH A+   DII A++++K R ++FL  P  YY  L ++L    + V EDL  + +L+IL+DFD+NGYLLQIF+K +QDRPT+F+E+IQR N  GFGAGNFK+LF+A+E +QE+RG L
Sbjct:    2 GSISAIHHIEFIVSNALQSAYWYCSGFGFEKFA-EKITDESTSIALRNGTARVIITSYNSQNIYT------DQLIKHGDFIKDVSFRVDNLDAVLQNLVENDIKVIQQSEV-STKDGLVRTATLLSEGGDVTHTLFELGEFKGNFLPFFTPISNFELFENIEKMPAI-LMDHVVQNYPIGEMEAAADWYFKTMRLKRFWSVDDKVATSEFSAMTAWLLVNDDHTVQVTLAEGVKGRKGKSQIEEFINYHGGSGVQHFALLVEDIISAVQIMKSRSVEFLTIPSQYYDNLEERLSKTNLIVKEDLKMIRELNILMDFDENGYLLQIFSKPLQDRPTLFIEIIQRANFKGFGAGNFKALFDAVEREQEKRGTL 363
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Fly
Match: Hpd (gene:FBgn0036992 transcript:FBtr0078225)

HSP 1 Score: 518.079 bits (1333), Expect = 0.000e+0
Identity = 249/381 (65.35%), Postives = 302/381 (79.27%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKG K EAGKF SF  +TF VGNAKQAAS+Y  RLGF    YQGLETG R  A H V+QN I+F F S   P+  +E G HL  HGD VKD+AFEVEDL+AIF  AV +GA VV+DIW ESD+ G V+FA IKT+ DTTHTF++R+ Y G +LP ++    +  +N +  S  LNFIDH+VGNQPD QM ++  WYE+ LQFHRFWSVDDSQIHTEYSALRSIV+ NY+ETVK+PINEPA GK+KSQIQEYV+YYG GGVQHIA+NT+DII+A+  LK RG +FL  P +YY  L++QL  ++ K+ ED++ L+KL+ILIDFD+NGYLLQIFTKN QDRPT+FLEVIQR+NHNGFGAGNFKSLF AIE++Q +RGNL
Sbjct:    2 TSYTDKGTKPEAGKFLSFDHLTFYVGNAKQAASYYTTRLGFEPLGYQGLETGERRFAKHAVRQNKIVFVFVSAYTPDD-EEHGLHLMRHGDGVKDVAFEVEDLNAIFTLAVSRGAEVVRDIWEESDDQGFVRFATIKTYGDTTHTFVERNGYAGDFLPGFQRSPKDVLLNGL-PSTKLNFIDHVVGNQPDLQMESVASWYERILQFHRFWSVDDSQIHTEYSALRSIVMANYEETVKMPINEPANGKKKSQIQEYVEYYGGGGVQHIALNTDDIIEAVSNLKARGTEFLTIPSSYYEILQEQLSHSRTKIKEDMEVLKKLNILIDFDENGYLLQIFTKNCQDRPTLFLEVIQRYNHNGFGAGNFKSLFTAIEIEQAKRGNL 380
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Fly
Match: Hpd (gene:FBgn0036992 transcript:FBtr0078226)

HSP 1 Score: 420.239 bits (1079), Expect = 7.646e-147
Identity = 197/293 (67.24%), Postives = 243/293 (82.94%), Query Frame = 1 
Query:  328 HGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            HGD VKD+AFEVEDL+AIF  AV +GA VV+DIW ESD+ G V+FA IKT+ DTTHTF++R+ Y G +LP ++  + +D +     S  LNFIDH+VGNQPD QM ++  WYE+ LQFHRFWSVDDSQIHTEYSALRSIV+ NY+ETVK+PINEPA GK+KSQIQEYV+YYG GGVQHIA+NT+DII+A+  LK RG +FL  P +YY  L++QL  ++ K+ ED++ L+KL+ILIDFD+NGYLLQIFTKN QDRPT+FLEVIQR+NHNGFGAGNFKSLF AIE++Q +RGNL
Sbjct:    3 HGDGVKDVAFEVEDLNAIFTLAVSRGAEVVRDIWEESDDQGFVRFATIKTYGDTTHTFVERNGYAGDFLPGFQR-SPKDVLLNGLPSTKLNFIDHVVGNQPDLQMESVASWYERILQFHRFWSVDDSQIHTEYSALRSIVMANYEETVKMPINEPANGKKKSQIQEYVEYYGGGGVQHIALNTDDIIEAVSNLKARGTEFLTIPSSYYEILQEQLSHSRTKIKEDMEVLKKLNILIDFDENGYLLQIFTKNCQDRPTLFLEVIQRYNHNGFGAGNFKSLFTAIEIEQAKRGNL 294
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Zebrafish
Match: hpda (4-hydroxyphenylpyruvate dioxygenase a [Source:NCBI gene;Acc:394142])

HSP 1 Score: 499.59 bits (1285), Expect = 2.237e-176
Identity = 243/385 (63.12%), Postives = 299/385 (77.66%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFID-RSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL*VV 1215
            T+YTDKG K E GKF +F+ I F VGNAKQAA  YC + GF   AY+GLETG+REV +H VKQ+ IIF F S L P   +E+GEHL  HGD VKD+AF VED D +  KA E+GA V+K+ W E D  G VK+A ++T+ DTTHTF++    YKG++LP Y+     DP+     S  L+FIDHIVGNQPDD+M  + +WY+K L FHRFWS+DD QIHTEYSALRSIV+TNY+ET+K+PINEPA GK+KSQIQEY+DY G  GVQHIA+NT++II+AI  L+ RGL+FL AP  YY +LR++L++AKIKV EDL  L++L IL+DFDD GYLLQIFTK +QDRPT+FLEVIQR+NH GFGAGNFKSLFEAIE DQ+ RGNL V+
Sbjct:    2 TSYTDKGEKPERGKFLNFHHIKFWVGNAKQAAVFYCDKFGFEPLAYKGLETGSREVVSHAVKQDKIIFVFESALNPGN-EEMGEHLIKHGDGVKDVAFLVEDCDFLVKKAKERGAAVLKEPWVEQDAGGKVKYAIVQTYGDTTHTFVEYLGPYKGLFLPGYKEPLFRDPLLPKLPSGHLSFIDHIVGNQPDDEMVPVSDWYQKCLLFHRFWSIDDKQIHTEYSALRSIVVTNYEETIKMPINEPAMGKKKSQIQEYIDYNGGPGVQHIALNTSNIIQAIVNLRARGLEFLSAPDNYYESLREKLKTAKIKVKEDLKTLQELKILVDFDDKGYLLQIFTKPVQDRPTLFLEVIQRNNHFGFGAGNFKSLFEAIEKDQDARGNLTVL 385
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Zebrafish
Match: hpdb (4-hydroxyphenylpyruvate dioxygenase b [Source:ZFIN;Acc:ZDB-GENE-040808-62])

HSP 1 Score: 496.123 bits (1276), Expect = 3.751e-175
Identity = 237/381 (62.20%), Postives = 293/381 (76.90%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+Y DKG K E GKF  F  ITF VGNAKQAAS+YC +LGF   AY+GLETG+R+V +H VKQ  II+ F+S L P   KE+G+HL  HGD VKD+AF VE+ D +  KA E+GA ++K+     D+ G VK A ++T+ DTTHTF++R+ Y G++LP +      DP      S  L+FIDH+VGNQPD +M  IVEWY++ L FHRFWSVDD Q+ TEYSALRSIV+ NY+ETVK+PINEPA GKRKSQIQEYV+YYG  GVQHIAMNT+DII AI+ LK RG++F+  P TYY  L+++L+ +K+++ EDL+ LE+L IL+D+DDNGYLLQIFTK +QDRPTVFLEVIQRHNH GFGAGNFKSLFEAIE DQ  RGNL
Sbjct:    2 TSYIDKGEKHEEGKFICFDHITFWVGNAKQAASYYCNKLGFEPLAYRGLETGSRDVVSHAVKQGKIIYVFTSALNPGN-KEMGDHLVKHGDGVKDVAFTVENCDFLVEKARERGAIIIKESHAVEDKFGRVKMAVVQTYGDTTHTFVERTGYNGLFLPGFHAPLFCDPFLAKLPSGKLDFIDHVVGNQPDSEMVPIVEWYQRNLLFHRFWSVDDKQLQTEYSALRSIVVANYEETVKMPINEPAMGKRKSQIQEYVEYYGGAGVQHIAMNTSDIISAIRNLKERGMEFMSVPDTYYQQLKEKLKLSKVRIIEDLNILEELKILVDYDDNGYLLQIFTKPVQDRPTVFLEVIQRHNHQGFGAGNFKSLFEAIEADQNARGNL 381
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Zebrafish
Match: hpdb (4-hydroxyphenylpyruvate dioxygenase b [Source:ZFIN;Acc:ZDB-GENE-040808-62])

HSP 1 Score: 486.493 bits (1251), Expect = 1.806e-171
Identity = 232/371 (62.53%), Postives = 286/371 (77.09%), Query Frame = 1 
Query:   94 EAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            E GKF  F  ITF VGNAKQAAS+YC +LGF   AY+GLETG+REV +H VKQ  II+ F+S L P   KE+G+HL  HGD VKD+AF VE+ D +  KA E+GA ++K+     D+ G VK A ++T+ DTTHTF++R+ Y G++LP +      DP      S  L+FIDH+VGNQPD +M  IVEWY++ L FHRFWSVDD Q+ TEYSALRSIV+ NY+ETVK+PINEPA GKRKSQIQEYV+YYG  GVQHIAMNT+DII AI+ LK RG++F+  P TYY  L+++L+ +K+++ EDL+ LE+L IL+D+DDNGYLLQIFTK +QDRPTVFLEVIQRHNH GFGAGNFKSLFEAIE DQ  RGNL
Sbjct:    4 EEGKFICFDHITFWVGNAKQAASYYCNKLGFEPLAYRGLETGSREVVSHAVKQGKIIYVFTSALNPGN-KEMGDHLVKHGDGVKDVAFTVENCDFLVEKARERGAIIIKESHAVEDKFGRVKMAVVQTYGDTTHTFVERTGYNGLFLPGFHAPLFCDPFLAKLPSGKLDFIDHVVGNQPDSEMVPIVEWYQRNLLFHRFWSVDDKQLQTEYSALRSIVVANYEETVKMPINEPAMGKRKSQIQEYVEYYGGAGVQHIAMNTSDIISAIRNLKERGMEFMSVPDTYYQQLKEKLKLSKVRIIEDLNILEELKILVDYDDNGYLLQIFTKPVQDRPTVFLEVIQRHNHQGFGAGNFKSLFEAIEADQNARGNL 373
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Zebrafish
Match: hpda (4-hydroxyphenylpyruvate dioxygenase a [Source:NCBI gene;Acc:394142])

HSP 1 Score: 129.798 bits (325), Expect = 5.070e-36
Identity = 66/117 (56.41%), Postives = 81/117 (69.23%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHK-AVEKGAN 411
            T+YTDKG K E GKF +F+ I F VGNAKQAA  YC + GF   AY+GLETG+REV +H VKQ+ IIF F S L P   +E+GEHL  HGD VKD+AF VED D +  +  ++ G N
Sbjct:    2 TSYTDKGEKPERGKFLNFHHIKFWVGNAKQAAVFYCDKFGFEPLAYKGLETGSREVVSHAVKQDKIIFVFESALNPGN-EEMGEHLIKHGDGVKDVAFLVEDCDFLVKRMCLDCGGN 117
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Zebrafish
Match: hpdl (4-hydroxyphenylpyruvate dioxygenase-like [Source:ZFIN;Acc:ZDB-GENE-071004-50])

HSP 1 Score: 126.331 bits (316), Expect = 8.450e-32
Identity = 100/409 (24.45%), Postives = 175/409 (42.79%), Query Frame = 1 
Query:   97 AGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHG----------DAVKDIAFEVEDLDAIFHKAVEK-GANVVKDIWTESDENGTVKFARIKT-FYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYS------ALRSIVITNY---DETVKLP------------INEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILID-----------FDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQE 1191
            A      + I+  V N  + A    +R  F  FA +  +   +++A   +++   +F  +    P+    + +H  A            D V ++ FEV D+ +      ++ G   ++      D+ G V F+ +++   +  HT ID S+Y+G +LP +R ++           P  +F DHI    P     +I  WY +   F RF+   +  +   Y        LR   +  +   +  +KLP            I E    + ++Q+  ++D +   G+QHI + T DI+K  + L   G++F   P  YYT + KQ E   +    D   L +  IL+D            D   +LLQ+FTK +    T FLE+I+R    GFG GN ++L+ +++   E
Sbjct:    2 AAYLSRLHHISLQVSNVDKVAHELVSRFQFNVFAARRTDRA-KQLA---LRRGSAVFVVNERPSPSDCGAVRDHRDAGCVFGTHEHYPVDTVSNVCFEVTDVPSASRALRDQDGCEFLQPPAELQDDCGRVTFSIVRSPVGNVCHTLIDSSRYQGPFLPGFREVSSGCQGADRSRCPITHF-DHITYACPRSSTVHITNWYRRNFGFQRFFIDRNEDVDEGYVLNHDGIGLRLTAMEYWKCSESGIKLPFKDEKEPDCKFVIAESLPEQGRNQVDTFLDEHRGAGIQHIGLYTEDIVKTAQTLSQAGVQFFSPPPAYYTEVGKQQE--MLDAGYDPQTLSRYGILLDTDIQTDTDRQTTDGQRHLLQVFTKPVFAEDTFFLELIERRGATGFGEGNIRALWRSVQAYME 403
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Xenopus
Match: hpd (uncharacterized loc100125092 [Source:Xenbase;Acc:XB-GENE-5817456])

HSP 1 Score: 513.842 bits (1322), Expect = 0.000e+0
Identity = 246/382 (64.40%), Postives = 304/382 (79.58%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDR-SQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKG K   G+F SF+ +TF VGNAKQAAS YC + GF   AY+GLETG+R+V +H +KQ+ IIF F S L P   +E+G+H+  HGD VKD+AF+VED D +F KA + GA VV++ W E DE G VK+A ++T+ DTTHT ++    Y+GV+LP Y+     DP+     S  L+FIDHIVGNQPD++M  IVEWY+K L FHRFWSVDD QIHTEYS+LRSIV+TNY+ET+K+PINEPAAGK+KSQIQEYVDYYGS GVQHIA+NT++IIKA+K LK RG++FL AP TYY  LRK+L++AKI V EDL+ L++L IL+D+DD GYLLQIFTK MQDRPT+FLEVIQR+NH GFGAGNFKSLFEAIE DQ+ RGNL
Sbjct:    2 TSYTDKGEKHARGRFLSFHHLTFWVGNAKQAASFYCDKFGFEPCAYKGLETGSRDVVSHAIKQDKIIFVFQSPLNPGN-QEMGQHMIKHGDGVKDVAFQVEDCDFLFQKAKDHGAVVVREPWIEEDEGGKVKYAVLQTYGDTTHTLLEYLGPYRGVFLPGYKEPLFRDPLLPTLPSGCLSFIDHIVGNQPDNEMVPIVEWYQKCLLFHRFWSVDDKQIHTEYSSLRSIVVTNYEETIKMPINEPAAGKKKSQIQEYVDYYGSAGVQHIALNTSNIIKAVKNLKSRGIEFLSAPDTYYEELRKKLKTAKITVKEDLNVLQELKILVDYDDKGYLLQIFTKPMQDRPTLFLEVIQRYNHFGFGAGNFKSLFEAIETDQDARGNL 382
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Xenopus
Match: hpd (uncharacterized loc100125092 [Source:Xenbase;Acc:XB-GENE-5817456])

HSP 1 Score: 512.301 bits (1318), Expect = 0.000e+0
Identity = 246/382 (64.40%), Postives = 303/382 (79.32%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDR-SQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKG K   G+F SF+ +TF VGNAKQAAS YC + GF   AY+GLETG+R+V +H +KQ+ IIF F S L P   +E+G+H+  HGD VKD+AF+VED D +F KA + GA VV++ W E DE G VK+A ++T+ DTTHT ++    Y+GV+LP Y+     DP+     S  L+FIDHIVGNQPD++M  IVEWY K L FHRFWSVDD QIHTEYS+LRSIV+TNY+ET+K+PINEPAAGK+KSQIQEYVDYYGS GVQHIA+NT++IIKA+K LK RG++FL AP TYY  LRK+L++AKI V EDL+ L++L IL+D+DD GYLLQIFTK MQDRPT+FLEVIQR+NH GFGAGNFKSLFEAIE DQ+ RGNL
Sbjct:    2 TSYTDKGEKHARGRFLSFHHLTFWVGNAKQAASFYCDKFGFEPCAYKGLETGSRDVVSHAIKQDKIIFVFQSPLNPGN-QEMGQHMIKHGDGVKDVAFQVEDCDFLFQKAKDHGAVVVREPWIEEDEGGKVKYAVLQTYGDTTHTLLEYLGPYRGVFLPGYKEPLFRDPLLPTLPSGCLSFIDHIVGNQPDNEMVPIVEWYVKCLLFHRFWSVDDKQIHTEYSSLRSIVVTNYEETIKMPINEPAAGKKKSQIQEYVDYYGSAGVQHIALNTSNIIKAVKNLKSRGIEFLSAPDTYYEELRKKLKTAKITVKEDLNVLQELKILVDYDDKGYLLQIFTKPMQDRPTLFLEVIQRYNHFGFGAGNFKSLFEAIETDQDARGNL 382
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Xenopus
Match: hpd (4-hydroxyphenylpyruvate dioxygenase [Source:NCBI gene;Acc:779829])

HSP 1 Score: 504.212 bits (1297), Expect = 3.310e-178
Identity = 235/381 (61.68%), Postives = 295/381 (77.43%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKG K E G+F SF+ +T  V NAKQAAS YC +LGF   AY+GLETG+R++ THVVKQ+ II  F S L P   +E G HL  HGD VKD+AFEVED + +  KA ++GA +VK+ W E D+ G VKFA ++T+ DTTHT +++  Y G++LP Y     +DP+        LNFIDHIVGNQPDD+M ++ +WY+K L FHRFWSVDD Q+HTE+SALRSIV+ NY+ET+K+PINEPA GK++SQIQEYVDYYG  GVQHIA+NT+DII A+  L+ RG++F+  P  YY TLR+ L++AKIKV ED+D+LE+L IL+D+DDNGYLLQIFTK +QDRPT+F EVIQRHNH GFGAGNFKSLF+AIE DQ  RGNL
Sbjct:    2 TSYTDKGEKHEQGRFLSFHSVTLWVSNAKQAASFYCNKLGFEPLAYKGLETGSRKLVTHVVKQDKIILLFVSALTPGN-EEFGAHLQKHGDGVKDVAFEVEDCEFLVQKARQRGAVIVKEPWVEEDKFGKVKFAIVQTYGDTTHTLVEKLGYNGIFLPGYEPPLFQDPLLPKLPDCKLNFIDHIVGNQPDDEMVSVADWYQKALLFHRFWSVDDKQLHTEFSALRSIVVANYEETIKMPINEPAPGKKRSQIQEYVDYYGGPGVQHIALNTSDIITAVSNLQERGMEFMSVPSAYYQTLRENLKTAKIKVAEDIDKLEELKILVDYDDNGYLLQIFTKPVQDRPTLFFEVIQRHNHQGFGAGNFKSLFQAIEADQAARGNL 381
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Xenopus
Match: hpd (uncharacterized loc100125092 [Source:Xenbase;Acc:XB-GENE-5817456])

HSP 1 Score: 501.13 bits (1289), Expect = 6.040e-177
Identity = 239/370 (64.59%), Postives = 296/370 (80.00%), Query Frame = 1 
Query:  100 GKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDR-SQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            G+F SF+ +TF VGNAKQAAS YC + GF   AY+GLETG+R+V +H +KQ+ IIF F S L P   +E+G+H+  HGD VKD+AF+VED D +F KA + GA VV++ W E DE G VK+A ++T+ DTTHT ++    Y+GV+LP Y+     DP+     S  L+FIDHIVGNQPD++M  IVEWY+K L FHRFWSVDD QIHTEYS+LRSIV+TNY+ET+K+PINEPAAGK+KSQIQEYVDYYGS GVQHIA+NT++IIKA+K LK RG++FL AP TYY  LRK+L++AKI V EDL+ L++L IL+D+DD GYLLQIFTK MQDRPT+FLEVIQR+NH GFGAGNFKSLFEAIE DQ+ RGNL
Sbjct:   16 GRFLSFHHLTFWVGNAKQAASFYCDKFGFEPCAYKGLETGSRDVVSHAIKQDKIIFVFQSPLNPGN-QEMGQHMIKHGDGVKDVAFQVEDCDFLFQKAKDHGAVVVREPWIEEDEGGKVKYAVLQTYGDTTHTLLEYLGPYRGVFLPGYKEPLFRDPLLPTLPSGCLSFIDHIVGNQPDNEMVPIVEWYQKCLLFHRFWSVDDKQIHTEYSSLRSIVVTNYEETIKMPINEPAAGKKKSQIQEYVDYYGSAGVQHIALNTSNIIKAVKNLKSRGIEFLSAPDTYYEELRKKLKTAKITVKEDLNVLQELKILVDYDDKGYLLQIFTKPMQDRPTLFLEVIQRYNHFGFGAGNFKSLFEAIETDQDARGNL 384
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Xenopus
Match: hpd (4-hydroxyphenylpyruvate dioxygenase [Source:NCBI gene;Acc:779829])

HSP 1 Score: 488.804 bits (1257), Expect = 4.742e-172
Identity = 227/373 (60.86%), Postives = 287/373 (76.94%), Query Frame = 1 
Query:   88 KVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            K +  +F SF+ +T  V NAKQAAS YC +LGF   AY+GLETG+R++ THVVKQ+ II  F S L P   +E G HL  HGD VKD+AFEVED + +  KA ++GA +VK+ W E D+ G VKFA ++T+ DTTHT +++  Y G++LP Y     +DP+        LNFIDHIVGNQPDD+M ++ +WY+K L FHRFWSVDD Q+HTE+SALRSIV+ NY+ET+K+PINEPA GK++SQIQEYVDYYG  GVQHIA+NT+DII A+  L+ RG++F+  P  YY TLR+ L++AKIKV ED+D+LE+L IL+D+DDNGYLLQIFTK +QDRPT+F EVIQRHNH GFGAGNFKSLF+AIE DQ  RGNL
Sbjct:    7 KSDRCRFLSFHSVTLWVSNAKQAASFYCNKLGFEPLAYKGLETGSRKLVTHVVKQDKIILLFVSALTPGN-EEFGAHLQKHGDGVKDVAFEVEDCEFLVQKARQRGAVIVKEPWVEEDKFGKVKFAIVQTYGDTTHTLVEKLGYNGIFLPGYEPPLFQDPLLPKLPDCKLNFIDHIVGNQPDDEMVSVADWYQKALLFHRFWSVDDKQLHTEFSALRSIVVANYEETIKMPINEPAPGKKRSQIQEYVDYYGGPGVQHIALNTSDIITAVSNLQERGMEFMSVPSAYYQTLRENLKTAKIKVAEDIDKLEELKILVDYDDNGYLLQIFTKPVQDRPTLFFEVIQRHNHQGFGAGNFKSLFQAIEADQAARGNL 378
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Mouse
Match: Hpd (4-hydroxyphenylpyruvic acid dioxygenase [Source:MGI Symbol;Acc:MGI:96213])

HSP 1 Score: 489.574 bits (1259), Expect = 1.985e-172
Identity = 231/381 (60.63%), Postives = 287/381 (75.33%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            TTY +KGPK E G+F  F+ +TF VGNAKQAAS YC ++GF   AY+GLETG+REV +HV+KQ  I+F   S L P   KE+G+HL  HGD VKDIAFEVED D I  KA E+GA +V++ W E D+ G VKFA ++T+ DTTHT +++  Y G +LP +     +D +        L  IDHIVGNQPD +M +  EWY K LQFHRFWSVDD+Q+HTEYS+LRSIV+TNY+E++K+PINEPA G++KSQIQEYVDY G  GVQHIA+ T DII AI+ L+ RG +FL AP +YY  LR+ L+SAKI+V E +D LE+L IL+D+D+ GYLLQIFTK MQDRPT+FLEVIQRHNH GFGAGNF SLF+A E +Q  RGNL
Sbjct:    2 TTYNNKGPKPERGRFLHFHSVTFWVGNAKQAASFYCNKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLCSALNPWN-KEMGDHLVKHGDGVKDIAFEVEDCDHIVQKARERGAKIVREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKINYTGRFLPGFEAPTYKDTLLPKLPRCNLEIIDHIVGNQPDQEMQSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVTNYEESIKMPINEPAPGRKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGTEFLAAPSSYYKLLRENLKSAKIQVKESMDVLEELHILVDYDEKGYLLQIFTKPMQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQALRGNL 381
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Mouse
Match: Hpd (4-hydroxyphenylpyruvic acid dioxygenase [Source:MGI Symbol;Acc:MGI:96213])

HSP 1 Score: 163.31 bits (412), Expect = 2.765e-48
Identity = 79/160 (49.38%), Postives = 104/160 (65.00%), Query Frame = 1 
Query:  178 LGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVE 657
            +GF   AY+GLETG+REV +HV+KQ  I+F   S L P   KE+G+HL  HGD VKDIAFEVED D I  KA E+GA +V++ W E D+ G VKFA ++T+ DTTHT +++  Y G +LP +     +D +        L  IDHIVGNQPD +M +  E
Sbjct:    1 MGFEPLAYRGLETGSREVVSHVIKQGKIVFVLCSALNPWN-KEMGDHLVKHGDGVKDIAFEVEDCDHIVQKARERGAKIVREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKINYTGRFLPGFEAPTYKDTLLPKLPRCNLEIIDHIVGNQPDQEMQSASE 159
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Mouse
Match: Hpd (4-hydroxyphenylpyruvic acid dioxygenase [Source:MGI Symbol;Acc:MGI:96213])

HSP 1 Score: 120.939 bits (302), Expect = 5.355e-33
Identity = 57/88 (64.77%), Postives = 70/88 (79.55%), Query Frame = 1 
Query:  871 NTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHN 1134
             T DII AI+ L+ RG +FL AP +YY  LR+ L+SAKI+V E +D LE+L IL+D+D+ GYLLQIFTK MQDRPT+FLEVIQRHNH 
Sbjct:    2 KTEDIITAIRHLRERGTEFLAAPSSYYKLLRENLKSAKIQVKESMDVLEELHILVDYDEKGYLLQIFTKPMQDRPTLFLEVIQRHNHQ 89
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Mouse
Match: Hpdl (4-hydroxyphenylpyruvate dioxygenase-like [Source:MGI Symbol;Acc:MGI:2444646])

HSP 1 Score: 109.768 bits (273), Expect = 3.679e-26
Identity = 88/373 (23.59%), Postives = 165/373 (44.24%), Query Frame = 1 
Query:  109 KSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGN-REVATHVVKQNDIIFAFSSMLLPNKPK-EIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFY-DTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPG-LNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRF--WSVDDSQIHTEYSA------LRSIVI----TNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIE 1179
            +    I F V   +  A       GF   A +  E G  R++A   ++  D +F  +    P +P   +  H +    +  ++ F+VED+D        +G  +        D  GT  +  + +   + + T + R+ Y+G +LP +R +            PG ++ +DH+           ++ W+   L FH       +D ++  + +A      LR   +     N   T+ L  + P    ++ Q+++++  +G  G+QH+ + T +II A + +   G + L  P+ YY    K  E   +        LE+  IL+D D + +LLQ+FTK++    T FLE+IQR    GFG  N ++L+++++
Sbjct:    6 RRLCHIAFHVPAGQPLARDLHRVFGFQPLAVR--EAGGWRQLA---LRSGDAVFLVNEGTGPQEPLYSLDPHHSV--PSATNLCFDVEDVDGAARALAARGCIMPVPPTRVRDAQGTATYTVLSSPAGNLSLTLLQRAGYRGSFLPGFRPL-------PCTPGPGWVSHVDHLTLACTSGSSPMLMRWFHDCLGFHHLPLSPGEDPEMGLKVAAGSGRGGLRLTALQTPPNNTVPTLVLAESLPGLNSKQDQVEQFLTRHGGPGLQHVGLYTPNIIDASEGMAKAGCRLLTPPEAYYQQPGK--EEQILAAGHKPGLLERQGILLDGDKDEFLLQVFTKSLFAEDTFFLELIQRQGATGFGQNNIRALWQSVQ 362
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. UniProt/SwissProt
Match: sp|Q5BKL0|HPPD_XENTR (4-hydroxyphenylpyruvate dioxygenase OS=Xenopus tropicalis OX=8364 GN=hpd PE=2 SV=1)

HSP 1 Score: 513.842 bits (1322), Expect = 0.000e+0
Identity = 246/382 (64.40%), Postives = 304/382 (79.58%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDR-SQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKG K   G+F SF+ +TF VGNAKQAAS YC + GF   AY+GLETG+R+V +H +KQ+ IIF F S L P   +E+G+H+  HGD VKD+AF+VED D +F KA + GA VV++ W E DE G VK+A ++T+ DTTHT ++    Y+GV+LP Y+     DP+     S  L+FIDHIVGNQPD++M  IVEWY+K L FHRFWSVDD QIHTEYS+LRSIV+TNY+ET+K+PINEPAAGK+KSQIQEYVDYYGS GVQHIA+NT++IIKA+K LK RG++FL AP TYY  LRK+L++AKI V EDL+ L++L IL+D+DD GYLLQIFTK MQDRPT+FLEVIQR+NH GFGAGNFKSLFEAIE DQ+ RGNL
Sbjct:    2 TSYTDKGEKHARGRFLSFHHLTFWVGNAKQAASFYCDKFGFEPCAYKGLETGSRDVVSHAIKQDKIIFVFQSPLNPGN-QEMGQHMIKHGDGVKDVAFQVEDCDFLFQKAKDHGAVVVREPWIEEDEGGKVKYAVLQTYGDTTHTLLEYLGPYRGVFLPGYKEPLFRDPLLPTLPSGCLSFIDHIVGNQPDNEMVPIVEWYQKCLLFHRFWSVDDKQIHTEYSSLRSIVVTNYEETIKMPINEPAAGKKKSQIQEYVDYYGSAGVQHIALNTSNIIKAVKNLKSRGIEFLSAPDTYYEELRKKLKTAKITVKEDLNVLQELKILVDYDDKGYLLQIFTKPMQDRPTLFLEVIQRYNHFGFGAGNFKSLFEAIETDQDARGNL 382
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. UniProt/SwissProt
Match: sp|Q6TGZ5|HPPD_DANRE (4-hydroxyphenylpyruvate dioxygenase OS=Danio rerio OX=7955 GN=hpd PE=2 SV=1)

HSP 1 Score: 497.664 bits (1280), Expect = 7.629e-175
Identity = 241/385 (62.60%), Postives = 299/385 (77.66%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFID-RSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL*VV 1215
            T+YTDKG K E GKF +F+ I F VGNAKQAA  YC + GF   AY+GLETG+REV +H V+Q+ IIF F S L P   +E+GEH+  HGD VKD+AF VED D +  KA E+GA V+K+ W E D  G VK+A ++T+ DTTHTF++    YKG++LP Y+     DP+     S  L+FIDHIVGNQPDD+M  + +WY+K L FHRFWS+DD QIHTEYSALRSIV+TNY+ET+K+PINEPA GK+KSQIQEY+DY G  GVQHIA+NT++II+AI  L+ RGL+FL AP  YY +LR++L++AKIKV EDL  L++L IL+DFDD GYLLQIFTK +QDRPT+FLEVIQR+NH GFGAGNFKSLFEAIE DQ+ RGNL V+
Sbjct:    2 TSYTDKGEKPERGKFLNFHHIKFWVGNAKQAAVFYCDKFGFEPLAYKGLETGSREVVSHAVRQDKIIFVFESALNPGN-EEMGEHMIKHGDGVKDVAFLVEDCDFLVKKAKERGAAVLKEPWVEQDAGGKVKYAIVQTYGDTTHTFVEYLGPYKGLFLPGYKEPLFRDPLLPKLPSGHLSFIDHIVGNQPDDEMVPVSDWYQKCLLFHRFWSIDDKQIHTEYSALRSIVVTNYEETIKMPINEPAMGKKKSQIQEYIDYNGGPGVQHIALNTSNIIQAIVNLRARGLEFLSAPDNYYESLREKLKTAKIKVKEDLKTLQELKILVDFDDKGYLLQIFTKPVQDRPTLFLEVIQRNNHFGFGAGNFKSLFEAIEKDQDARGNLTVL 385
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. UniProt/SwissProt
Match: sp|Q5EA20|HPPD_BOVIN (4-hydroxyphenylpyruvate dioxygenase OS=Bos taurus OX=9913 GN=HPD PE=2 SV=3)

HSP 1 Score: 496.893 bits (1278), Expect = 1.503e-174
Identity = 235/381 (61.68%), Postives = 292/381 (76.64%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            TTY+DKG K E G+F  F+ +TF VGNAKQAAS+YC++LGF   AY+GLETG+REV +HVVKQ  I+F FSS L P   KE+G+HL  HGD VKDIAFEVED D I  KA E+GA +V++ W E D+ G VKFA ++T+ DTTHT +++  Y G +LP +      DP      S  L  IDHIVGNQPD +M +  EWY K LQFHRFWSVDD+Q+HTEYS+LRS+V+ NY+E++K+PINEPA GK+KSQIQEYVDY G  GVQHIA+ T DII AI+ L+ RG++FL  P TYY  LR++L+ AKI+V E++D LE+L IL+D+D+ GYLLQIFTK MQDRPT+FLEVIQRHNH GFGAGNF SLF+A E +Q+ RGNL
Sbjct:    2 TTYSDKGEKPERGRFLHFHSVTFWVGNAKQAASYYCSKLGFEPLAYKGLETGSREVVSHVVKQGQIVFVFSSALNPWN-KEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIVREPWVEQDKLGKVKFAVLQTYGDTTHTLVEKMNYTGRFLPGFEAPPFMDPQLSKLPSCSLEIIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSVVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTKDIITAIRHLRERGVEFLAVPSTYYKQLREKLKMAKIRVKENIDILEELKILVDYDEKGYLLQIFTKPMQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQDLRGNL 381
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. UniProt/SwissProt
Match: sp|P32754|HPPD_HUMAN (4-hydroxyphenylpyruvate dioxygenase OS=Homo sapiens OX=9606 GN=HPD PE=1 SV=2)

HSP 1 Score: 494.582 bits (1272), Expect = 1.279e-173
Identity = 233/381 (61.15%), Postives = 290/381 (76.12%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            TTY+DKG K E G+F  F+ +TF VGNAKQAAS YC+++GF   AY+GLETG+REV +HV+KQ  I+F  SS L P   KE+G+HL  HGD VKDIAFEVED D I  KA E+GA ++++ W E D+ G VKFA ++T+ DTTHT +++  Y G +LP Y      DP+        L  IDHIVGNQPD +M +  EWY K LQFHRFWSVDD+Q+HTEYS+LRSIV+ NY+E++K+PINEPA GK+KSQIQEYVDY G  GVQHIA+ T DII AI+ L+ RGL+FL  P TYY  LR++L++AKIKV E++D LE+L IL+D+D+ GYLLQIFTK +QDRPT+FLEVIQRHNH GFGAGNF SLF+A E +Q  RGNL
Sbjct:    2 TTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWN-KEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQNLRGNL 381
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. UniProt/SwissProt
Match: sp|P49429|HPPD_MOUSE (4-hydroxyphenylpyruvate dioxygenase OS=Mus musculus OX=10090 GN=Hpd PE=1 SV=3)

HSP 1 Score: 489.574 bits (1259), Expect = 1.388e-171
Identity = 231/381 (60.63%), Postives = 287/381 (75.33%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            TTY +KGPK E G+F  F+ +TF VGNAKQAAS YC ++GF   AY+GLETG+REV +HV+KQ  I+F   S L P   KE+G+HL  HGD VKDIAFEVED D I  KA E+GA +V++ W E D+ G VKFA ++T+ DTTHT +++  Y G +LP +     +D +        L  IDHIVGNQPD +M +  EWY K LQFHRFWSVDD+Q+HTEYS+LRSIV+TNY+E++K+PINEPA G++KSQIQEYVDY G  GVQHIA+ T DII AI+ L+ RG +FL AP +YY  LR+ L+SAKI+V E +D LE+L IL+D+D+ GYLLQIFTK MQDRPT+FLEVIQRHNH GFGAGNF SLF+A E +Q  RGNL
Sbjct:    2 TTYNNKGPKPERGRFLHFHSVTFWVGNAKQAASFYCNKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLCSALNPWN-KEMGDHLVKHGDGVKDIAFEVEDCDHIVQKARERGAKIVREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKINYTGRFLPGFEAPTYKDTLLPKLPRCNLEIIDHIVGNQPDQEMQSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVTNYEESIKMPINEPAPGRKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGTEFLAAPSSYYKLLRENLKSAKIQVKESMDVLEELHILVDYDEKGYLLQIFTKPMQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQALRGNL 381
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. TrEMBL
Match: K1QX22 (4-hydroxyphenylpyruvate dioxygenase OS=Crassostrea gigas OX=29159 GN=CGI_10022007 PE=4 SV=1)

HSP 1 Score: 592.038 bits (1525), Expect = 0.000e+0
Identity = 274/392 (69.90%), Postives = 325/392 (82.91%), Query Frame = 1 
Query:   31 LHLKFVAYKMGTTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            L+ K V    GTTYT+KGPK E+G+F  F  +TF VGNAKQAAS+YC R+GF  FAY+GLETG+R+V +H VKQN +IF F S L P+ PKEIGEHL  HGD VKDIAFEVEDL AIF +AV KGA VVK+ W ESD++GTVK A IKT+ DTTHT IDRS YKG++LP YR    +DP+ ++   P L FIDHIVGNQPD++M +I +WYEK L FHRFWSVDDSQIHTEYSALRSIV+TN++ET+K+PINEPA GKRKSQIQEYVDYYG  GVQHIAMNTNDII+ + +L+ RGL+FL+ P TYY  LR++L+ +K+KVTEDLD+++KL ILID+DD+GYLLQIFTK MQDRPT+FLEVIQRHNH GFGAGNFKSLFEAIE+DQ ERGNL
Sbjct: 1480 LNYKVVVDMDGTTYTNKGPKPESGRFVCFDHLTFWVGNAKQAASYYCTRVGFEPFAYKGLETGSRQVVSHAVKQNKMIFNFQSALEPDNPKEIGEHLVKHGDGVKDIAFEVEDLQAIFKRAVAKGAIVVKEPWEESDDSGTVKMAMIKTYGDTTHTLIDRSGYKGLFLPGYRASTFKDPLVELLPKPNLQFIDHIVGNQPDNEMTSIADWYEKNLMFHRFWSVDDSQIHTEYSALRSIVVTNFEETIKMPINEPAPGKRKSQIQEYVDYYGGAGVQHIAMNTNDIIQTVSLLRERGLQFLEIPSTYYKNLRERLKKSKVKVTEDLDKIQKLHILIDYDDDGYLLQIFTKIMQDRPTLFLEVIQRHNHQGFGAGNFKSLFEAIELDQAERGNL 1871
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. TrEMBL
Match: A0A210PRQ4 (4-hydroxyphenylpyruvate dioxygenase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT16203 PE=3 SV=1)

HSP 1 Score: 585.489 bits (1508), Expect = 0.000e+0
Identity = 270/381 (70.87%), Postives = 321/381 (84.25%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            TTYTDKG K E+G+F SF  ITF VGNAKQAASHYCARLGF   AY+GLETG+REVA HVV+QN I+F F SML P+KPKE+GEHL  HGD+VKD+AFEVEDLDAIF +A+E+GA VVK  W E+DE GTVKFA +KT+ DTTHTF+DRS+YKG +LP YR I  +DP+  +    GLNFIDHIVGNQP+D M ++ EWYE+ L FHRFWSVDD QIHTEYSALRSIV+TNY+ET+K+PINEPA+G+RKSQIQEYVD+ G  GVQHIAMNTNDII+ +  +K RG +FL+ P  YY  LRK+L+ + IKVTE++D L+KL IL+DFD+NGYLLQIFT+ MQDRPTVFLEVIQRHN++GFGAGNFKSLFEAIE++Q ERGNL
Sbjct:    2 TTYTDKGEKPESGRFVSFDHITFWVGNAKQAASHYCARLGFELLAYKGLETGSREVAAHVVRQNKIMFVFQSMLQPHKPKEMGEHLVKHGDSVKDVAFEVEDLDAIFTRAIERGAIVVKKPWEETDEGGTVKFAMVKTYGDTTHTFVDRSKYKGAFLPGYRAITIQDPLCDLLPKTGLNFIDHIVGNQPEDDMVSVAEWYERNLMFHRFWSVDDKQIHTEYSALRSIVVTNYEETIKMPINEPASGRRKSQIQEYVDFNGGAGVQHIAMNTNDIIETVTRMKARGQQFLEIPTKYYDNLRKRLKLSNIKVTENMDTLQKLRILVDFDENGYLLQIFTRMMQDRPTVFLEVIQRHNNSGFGAGNFKSLFEAIELEQAERGNL 382
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. TrEMBL
Match: A0A1I8IMR3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 581.637 bits (1498), Expect = 0.000e+0
Identity = 264/378 (69.84%), Postives = 317/378 (83.86%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEER 1197
            T+YTDKGPK + GKFK+F  +TF VGNAKQAA+HYCARLGF   AY+GLETG+R+VA+HVV+QN +IF F SML P KP+E+G+HL  HGD VKDIAFEVEDLD I+ KA++ GA VV++ WTESD+NG+V+FAR+KT+ DTTHTF +RS Y G++LPN+ +   EDP+  +    GL FIDHIVGNQP+D+M  + +WYEKTL FHRFWSVDD QIHT+YSALRSIV+TN++ET+K+PINEPA GKRKSQIQEYVDYYG  GVQHIA+NTNDII+ I  LK RG  FL+ P  YY  LR +L+ AKIKVTED+D+L+KL IL+D+DD+GYLLQIFTKNMQDRPT+FLEVIQRHNH GFGAGNFKSLFEAIE DQ ER
Sbjct:  610 TSYTDKGPKPDKGKFKAFGHVTFWVGNAKQAAAHYCARLGFKPLAYRGLETGSRQVASHVVQQNRVIFVFESMLEPFKPEEMGQHLIKHGDGVKDIAFEVEDLDGIYKKAIDCGAAVVREPWTESDKNGSVRFARMKTYGDTTHTFFERSSYTGLFLPNF-VPAKEDPLLSLLPEVGLQFIDHIVGNQPNDEMAGVADWYEKTLMFHRFWSVDDKQIHTDYSALRSIVVTNWEETIKMPINEPAPGKRKSQIQEYVDYYGGAGVQHIALNTNDIIQTITDLKARGQMFLEVPDKYYDNLRARLKHAKIKVTEDMDKLQKLKILVDYDDDGYLLQIFTKNMQDRPTLFLEVIQRHNHQGFGAGNFKSLFEAIEQDQAER 986
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. TrEMBL
Match: A0A267H602 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027845g1 PE=4 SV=1)

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 268/381 (70.34%), Postives = 320/381 (83.99%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKGPK + GKFK+F  +TF VGNAKQAA+HYCARLGF   AY+GLETG+R+VA+HVV+QN +IF F SML P KP+E+G+HL  HGD VKDIAFEVEDLD I+ KA++ GA VV++ WTESD+NG+V+FAR+KT+ DTTHTF +RS Y G++LPN+ +   EDP+  +    GL FIDHIVGNQP+D+M  + +WYEKTL FHRFWSVDD QIHT+YSALRSIV+TN+DET+K+PINEPA GKRKSQIQEYVDYYG  GVQHIA+NTNDII+ I  LK RG  FL+ P  YY  LR +L+ AKIKVTED+D+L+KL IL+D+DD+GYLLQIFTKNMQDRPT+FLEVIQRHNH GFGAGNFKSLFEAIE DQ ERGNL
Sbjct:    1 TSYTDKGPKPDKGKFKAFGHVTFWVGNAKQAAAHYCARLGFKPLAYRGLETGSRQVASHVVQQNRVIFVFESMLEPFKPEEMGQHLIKHGDGVKDIAFEVEDLDGIYKKAIDCGAAVVREPWTESDKNGSVRFARVKTYGDTTHTFFERSSYTGLFLPNF-VPAKEDPLLSLLPEVGLQFIDHIVGNQPNDEMAGVADWYEKTLMFHRFWSVDDKQIHTDYSALRSIVVTNWDETIKMPINEPAPGKRKSQIQEYVDYYGGAGVQHIALNTNDIIQTITDLKARGQMFLEVPDKYYDNLRARLKHAKIKVTEDMDKLQKLKILVDYDDDGYLLQIFTKNMQDRPTLFLEVIQRHNHQGFGAGNFKSLFEAIEQDQAERGNL 380
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. TrEMBL
Match: A0A267E053 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017936g2 PE=4 SV=1)

HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0
Identity = 264/380 (69.47%), Postives = 317/380 (83.42%), Query Frame = 1 
Query:   67 TYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            +YTDKGPK + GKFK+F  +TF VGNAKQAA+HYCARLGF   AY+GLETG+R+VA+HVV+QN +IF F SML P KP+E+G+HL  HGD VKDIAFEVEDLD I+ KA++ GA VV++ WTESD+NG+V+FAR+KT+ DTTHTF +RS Y G++LPN+ +   EDP+  +    GL FIDHIVGNQP+D+M  + +WYEKTL FHRFWSVDD QIHT+YSALRSIV+TN++ET+K+PINEPA GKRKSQIQEYVDYYG  GVQHIA+NTNDII+ I  LK RG  FL+ P  YY  LR +L+ AKIKVTED+D+L+KL IL+D+DD+GYLLQIFTKNMQDRPT+FLEVIQRHNH GFGAGNFKSLFEAIE DQ ERG  
Sbjct:    1 SYTDKGPKPDKGKFKAFGHVTFWVGNAKQAAAHYCARLGFKPLAYRGLETGSRQVASHVVQQNRVIFVFESMLEPFKPEEMGQHLIKHGDGVKDIAFEVEDLDGIYKKAIDCGAAVVREPWTESDKNGSVRFARVKTYGDTTHTFFERSSYTGLFLPNF-VPAKEDPLLSLLPEVGLQFIDHIVGNQPNDEMAGVADWYEKTLMFHRFWSVDDKQIHTDYSALRSIVVTNWEETIKMPINEPAPGKRKSQIQEYVDYYGGAGVQHIALNTNDIIQTITDLKARGQMFLEVPDKYYDNLRARLKHAKIKVTEDMDKLQKLKILVDYDDDGYLLQIFTKNMQDRPTLFLEVIQRHNHQGFGAGNFKSLFEAIEQDQAERGRF 379
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Cavefish
Match: hpda (4-hydroxyphenylpyruvate dioxygenase [Source:NCBI gene;Acc:103021345])

HSP 1 Score: 503.056 bits (1294), Expect = 7.844e-178
Identity = 238/382 (62.30%), Postives = 304/382 (79.58%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFID-RSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKG K E GKF  F+ +TF VGNAKQAA+ YC ++GF   AY+GLETG+RE+ +HV+KQ+ I+F F S L P   +E+G HL  HGD+VKDIAF+VED D +  KA E+GA +VK+ W E D++G VK+A ++T+ DTTHT ++  + YKG++LP Y+    +DP+        L+FIDHIVGNQPDD+M  I +WY+K L FHRFWS+DD QIHT+YS+LRSIV+TNY+ET+K+PINEPA GK+KSQIQEYVDY G  GVQHIA+NT+DIIKAI  LK RG++FL AP +YY +LR++L++AKIKV EDL  L++L IL+D+DD GYLLQIF+K +QDRPT+FLEVIQR+NH GFGAGNFKSLFEAIE DQ+ RGNL
Sbjct:    2 TSYTDKGEKPERGKFVRFHHLTFWVGNAKQAAAFYCDKMGFEPVAYKGLETGSREIVSHVIKQDKILFVFESALNPGN-EEMGRHLMQHGDSVKDIAFQVEDCDFLVKKAKERGAVIVKEPWVEQDKHGKVKYAVVQTYGDTTHTLVEYMTPYKGLFLPGYQEPLFKDPLLPKLPPGCLSFIDHIVGNQPDDEMVPISDWYQKCLMFHRFWSIDDKQIHTQYSSLRSIVVTNYEETIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALNTSDIIKAIVNLKARGMEFLSAPDSYYDSLREKLKTAKIKVKEDLKTLQELKILVDYDDKGYLLQIFSKPVQDRPTLFLEVIQRNNHFGFGAGNFKSLFEAIEKDQDARGNL 382
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Cavefish
Match: hpdb (4-hydroxyphenylpyruvate dioxygenase [Source:NCBI gene;Acc:103024912])

HSP 1 Score: 494.967 bits (1273), Expect = 1.058e-174
Identity = 239/384 (62.24%), Postives = 293/384 (76.30%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL*VV 1215
            TTYTDKG K E G+F  F  ITF VGNAKQAAS YC +LGF   AY GLETG+R++ +HVVKQ  II+ FSS L P   KE+GEHL  HGD VKD+AF V + + +  KA E+GA VVK+     D+ G VK A ++T+ DTTHT ++R  Y G++LP +      DP+        L+FIDH+VGNQPDD+M  +VEWY+K L FHRFWSVDD Q+ T++SALRSIV+ NY+ETVK+PINEPA GKRKSQIQEYV+YYG  GVQHIAMNT++II+AI+ LK RG++F+  P TYY  LR+ L+ +K+K+TED+  LE+L IL+D+DDNGYLLQIFTK +QDRPTVFLEVIQRHNH GFGAGNFKSLFEAIE DQ  RGNL V+
Sbjct:    2 TTYTDKGEKHEQGRFVCFDHITFWVGNAKQAASFYCNKLGFEPLAYSGLETGSRDMVSHVVKQGKIIYVFSSALNPGN-KEMGEHLVQHGDGVKDVAFTVNNCEFLVQKARERGAIVVKEPHVLEDKFGRVKLAVLQTYGDTTHTLVEREGYNGLFLPGFHAPLFRDPLLDKLPCGKLDFIDHVVGNQPDDEMVPVVEWYQKNLLFHRFWSVDDKQLQTQFSALRSIVVANYEETVKMPINEPAMGKRKSQIQEYVEYYGGPGVQHIAMNTSNIIEAIRNLKERGMEFMSVPGTYYQQLRENLKLSKVKITEDISILEELKILVDYDDNGYLLQIFTKPVQDRPTVFLEVIQRHNHQGFGAGNFKSLFEAIEADQNARGNLTVL 384
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Cavefish
Match: hpda (4-hydroxyphenylpyruvate dioxygenase [Source:NCBI gene;Acc:103021345])

HSP 1 Score: 394.045 bits (1011), Expect = 9.679e-136
Identity = 201/383 (52.48%), Postives = 260/383 (67.89%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFID-RSQYKGVYLPNYRLINDEDPINKIFESPGL-NFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKG K E GKF  F+ +TF VGNAKQAA+ YC ++GF   AY+GLETG+RE+ +HV+KQ+ I+F F S L P   +E+G HL  HGD+VKDIAF+VED D +  KA E+GA +VK+ W E D++G VK+A ++T+ DTTHT ++  + YKG++LP Y+          +F+ P L   + H   +     + ++   Y+K L FHRFWS+DD QIHT+YS+LRSIV+TNY+ET+K+PINEPA GK+KSQIQEYVDY G  GVQHIA+NT+DIIKA                                         +L IL+D+DD GYLLQIF+K +QDRPT+FLEVIQR+NH GFGAGNFKSLFEAIE DQ+ RGNL
Sbjct:    2 TSYTDKGEKPERGKFVRFHHLTFWVGNAKQAAAFYCDKMGFEPVAYKGLETGSREIVSHVIKQDKILFVFESALNPGN-EEMGRHLMQHGDSVKDIAFQVEDCDFLVKKAKERGAVIVKEPWVEQDKHGKVKYAVVQTYGDTTHTLVEYMTPYKGLFLPGYQ--------EPLFKDPLLPKLMPHCCSH-----LLSVSLRYQKCLMFHRFWSIDDKQIHTQYSSLRSIVVTNYEETIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALNTSDIIKA-----------------------------------------ELKILVDYDDKGYLLQIFSKPVQDRPTLFLEVIQRNNHFGFGAGNFKSLFEAIEKDQDARGNL 329
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Cavefish
Match: hpdl (4-hydroxyphenylpyruvate dioxygenase-like [Source:ZFIN;Acc:ZDB-GENE-071004-50])

HSP 1 Score: 100.908 bits (250), Expect = 6.269e-23
Identity = 76/299 (25.42%), Postives = 138/299 (46.15%), Query Frame = 1 
Query:  334 DAVKDIAFEVEDLDAIFHKAVEKGANVVKDIW--TESDENGTVKFARIKTFY-DTTHTFIDRSQYK--GVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFW-----SVDDSQI-----------HTEYSALRSIVIT-----NYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFD----------DNG-YLLQIFTKNMQDRPTVFLEVIQ 1119
            D+  ++ FEVED+     +  ++G +V+       + D  G+V ++ I++   +  HT +DRS+Y+  G +LP ++ + D          P  +F DH+    P      +++WY++   F RF+      VD+  +             EY     I ++     +     K  I E    K ++Q+  ++  +   G+QHI ++T +I+   + +   G++F   P  YYT + KQ E   ++      +L++  IL+D D           NG YLLQ+FTK +    T FLE+I+
Sbjct:   87 DSACNVCFEVEDVTESCARLSDRGCDVLVPPTEVCDPDGGGSVTYSVIRSVVGNVCHTLLDRSRYQDQGGFLPGFQRVGDGTDSEPDSRCPVTHF-DHVTFACPRRSTGEVMKWYQENFGFQRFFIGSNEDVDEGYVLNQDGIGLRLTAMEYWKCSEIGLSIPFKDSQTPDCKFVIAESLPEKGQNQVDTFLKQHRGPGIQHIGLSTQNIVSTAETMAQAGVEFFTPPPAYYTEVGKQQE--ILEAGHHPKELKQHGILLDTDLRNHEDSSTMPNGRYLLQVFTKPIFSEDTFFLELIE 382
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001974.1 (pep scaffold:Pmarinus_7.0:GL487872:2:2713:1 gene:ENSPMAG00000001795.1 transcript:ENSPMAT00000001974.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.14 bits (383), Expect = 1.885e-45
Identity = 70/101 (69.31%), Postives = 82/101 (81.19%), Query Frame = 1 
Query:  913 RGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL*VV 1215
            RG++F+  P TYY  L ++L  AKIKV EDLD+L +L IL+DFDD GYLLQIF+K MQDRPT+FLEVIQRHNH GFG GNFKSLFEAIE DQ  RGNL ++
Sbjct:    2 RGMEFMSVPDTYYDLLYEKLACAKIKVVEDLDKLRELKILVDFDDKGYLLQIFSKPMQDRPTLFLEVIQRHNHQGFGVGNFKSLFEAIEADQNARGNLTII 102
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Nematostella
Match: EDO35286 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLZ3])

HSP 1 Score: 120.553 bits (301), Expect = 8.364e-31
Identity = 92/334 (27.54%), Postives = 155/334 (46.41%), Query Frame = 1 
Query:  334 DAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKT-FYDTTHTFIDRSQYKGVYLPNYRLINDED--PINKIFESPG--LNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFW-------------------SVDDSQIHTEYSALRSIVI-----TNYDETVKLPINEPAAGKR--------KSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRK--QLESAKIKVTEDLDQLEKLSILIDF--------------DDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAI 1176
            D VKDIA EVE++          G  V++      D  GTV  + I++   +  H+ ++ ++Y G++LP ++    +    +N  F  P   +  +DH+        M  I++WY K L F RF                    SV       EY     I I     ++ D  VK  + E   G+          +QI+ ++  +G  GVQHI ++T+DI +A+      G+  +  P+ YY  + K  ++E A     + ++ L + +IL+D               D++ YL+Q+FTK + D+ T F+E+IQRH   GFGAGN ++L++A+
Sbjct:    1 DTVKDIALEVENVSYATEIVAVNGGTVLEFTKVCDDCYGTVTSSMIRSPCGNVCHSLLNTTKYTGLFLPGFKRSPTQTYCQLNFNFTKPNNVITHVDHVAIACEKGSMLEIIDWYVKCLGFKRFCLNSSEESDGFTIESPVNSASVGLKLTAMEYWRCNEIGIESNKDSHLDGAVKFVLAEALPGQGFFSDLFSGSNQIETFLHAHGGPGVQHIGLHTSDIARAMDEWTKAGVSIIPQPREYYNQVEKIKEIEQAG----KSVNSLMEHNILLDAESIDHKSENNQASTDNSVYLMQVFTKPLFDQDTFFMELIQRHGATGFGAGNIQALWKAL 330
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Medaka
Match: hpda (4-hydroxyphenylpyruvate dioxygenase [Source:NCBI gene;Acc:101165831])

HSP 1 Score: 504.212 bits (1297), Expect = 2.243e-178
Identity = 242/382 (63.35%), Postives = 300/382 (78.53%), Query Frame = 1 
Query:   64 TTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFID-RSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            T+YTDKG K   GKF SF+ +TF VGNAKQAAS YC ++GF   AY+GLETG RE+ +HV++Q+ IIF F S L P   +E+GEHL  HGDAVKDIAF+VED D +   A E+GA +VK+ W E D +G VK+  I+T+ DTTHT I+    YKG++LP+Y+     DP+       GL FIDHIVGNQPDDQM  + +WY+K L FHRFWS+DD QIHT+YSALRSIV+TNY+ET+K+PINEPA GK+KSQIQEYVDY G  GVQHIA+NT++II+AI  L+ RG++FL AP++YY +LRK+L++A  KV EDLD+L++L IL+DFDD GYLLQIFTK +QDRPT+FLEVIQR NH GFGAGNFKSLFEAIE DQ+ RGNL
Sbjct:    2 TSYTDKGEKPPRGKFISFHHVTFWVGNAKQAASFYCDKMGFEPLAYKGLETGTREMVSHVIRQDKIIFQFQSPLNPGN-EEMGEHLIKHGDAVKDIAFKVEDCDFLVKMAKERGAVIVKEPWVEQDSHGRVKYGVIQTYGDTTHTLIEYLGPYKGLFLPDYKEPLFRDPLLPKLPPAGLKFIDHIVGNQPDDQMVPVSDWYQKCLMFHRFWSIDDKQIHTQYSALRSIVVTNYEETIKMPINEPAMGKKKSQIQEYVDYNGGPGVQHIALNTSNIIQAIVNLRERGMEFLSAPESYYESLRKKLKAANFKVDEDLDRLQELKILVDFDDKGYLLQIFTKPVQDRPTLFLEVIQRKNHFGFGAGNFKSLFEAIEKDQDARGNL 382
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Medaka
Match: hpdb (4-hydroxyphenylpyruvate dioxygenase-like [Source:NCBI gene;Acc:101157460])

HSP 1 Score: 427.943 bits (1099), Expect = 2.247e-149
Identity = 212/359 (59.05%), Postives = 256/359 (71.31%), Query Frame = 1 
Query:  139 GNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL*VV 1215
            GNAKQAAS+YC +LGF   AYQGLETG+REV +H VKQ  II+ FSS L P   KE+G+H+  HGD VKDIAF VED D +  KA E+GAN++K+  T  D+ G V+ A ++T+ DTTHTF++++ YKG++LP +     +DP+     S  L+FIDH+VGNQPDD+M  IV+WY+KTL FHRFWSVDD Q+ TE+SALRSIV+ NY+ETVK+PINEPA GKRKSQIQEYVDYYG  GVQHIAMNT+DII +                                         +L ILID+DDNGYLLQIFTK +QDRPTVFLEVIQRHNH GFGAGNFKSLFEAIE DQ+ RGNL V+
Sbjct:    1 GNAKQAASYYCNKLGFEPLAYQGLETGSREVVSHAVKQGKIIYVFSSALNPGN-KEMGDHMVKHGDGVKDIAFTVEDCDFLVQKARERGANIIKEPHTLEDKKGKVRLAVLRTYGDTTHTFVEKTGYKGLFLPGFHPPLFQDPLLTKLPSGKLDFIDHVVGNQPDDEMVPIVDWYQKTLLFHRFWSVDDKQLQTEFSALRSIVVANYEETVKMPINEPAMGKRKSQIQEYVDYYGGPGVQHIAMNTSDIITS-----------------------------------------ELKILIDYDDNGYLLQIFTKPVQDRPTVFLEVIQRHNHQGFGAGNFKSLFEAIEADQQARGNLTVL 317
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Medaka
Match: hpda (4-hydroxyphenylpyruvate dioxygenase [Source:NCBI gene;Acc:101165831])

HSP 1 Score: 410.994 bits (1055), Expect = 1.387e-142
Identity = 206/358 (57.54%), Postives = 250/358 (69.83%), Query Frame = 1 
Query:  136 VGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFID-RSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            VGNAKQAAS YC ++GF   AY+GLETG RE+ +HV++Q+ IIF F S L P   +E+GEHL  HGDAVKDIAF+VED D +   A E+GA +VK+ W E D +G VK+  I+T+ DTTHT I+    YKG++LP+Y+     DP+       GL FIDHIVGNQPDDQM  + +WY+K L FHRFWS+DD QIHT+YSALRSIV+TNY+ET+K+PINEPA GK+KSQIQEYVDY G  GVQHIA+NT++II+A                                         +L IL+DFDD GYLLQIFTK +QDRPT+FLEVIQR NH GFGAGNFKSLFEAIE DQ+ RGNL
Sbjct:    1 VGNAKQAASFYCDKMGFEPLAYKGLETGTREMVSHVIRQDKIIFQFQSPLNPGN-EEMGEHLIKHGDAVKDIAFKVEDCDFLVKMAKERGAVIVKEPWVEQDSHGRVKYGVIQTYGDTTHTLIEYLGPYKGLFLPDYKEPLFRDPLLPKLPPAGLKFIDHIVGNQPDDQMVPVSDWYQKCLMFHRFWSIDDKQIHTQYSALRSIVVTNYEETIKMPINEPAMGKKKSQIQEYVDYNGGPGVQHIALNTSNIIQA-----------------------------------------ELKILVDFDDKGYLLQIFTKPVQDRPTLFLEVIQRKNHFGFGAGNFKSLFEAIEKDQDARGNL 316
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Medaka
Match: hpdl (4-hydroxyphenylpyruvate dioxygenase like [Source:NCBI gene;Acc:101165105])

HSP 1 Score: 136.346 bits (342), Expect = 2.334e-35
Identity = 88/321 (27.41%), Postives = 156/321 (48.60%), Query Frame = 1 
Query:  334 DAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFY-DTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFW-----SVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKR----------------KSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFD-------------DNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQE 1191
            D+V ++ FEVED++         G + +    T  D+NG V ++ +K+   +  HT +D+++Y G +LP +  + ++D  ++  +S  +   DHI    P      ++ WYEK   F RF+      VD+  +  +      +    Y +  K  I+ P A ++                ++Q+  +++++ + G+QHIA+ TN+I+    ++   G++F   P  YYT + KQLE    +V  D   L +  IL+D D             +  YLLQ+FTK +    T FLE+I+R    GFG GN K+L+ +++   E
Sbjct:   99 DSVSNVCFEVEDVERSARDLHHLGCSFLVPPTTVEDQNGLVTYSVVKSVVGNVCHTLVDKTKYGGAFLPGFD-VTEQDWSSE--DSDSVTHFDHITYACPRKSTQQVMSWYEKMFGFKRFFIDRNEDVDEGFVVNQKGVGLRLTAMQYWKCSKAGISVPFADRKEPDCKFVIAESLPHQGRNQVDTFLEHHRAPGIQHIALYTNNIVSTANLMAAAGVQFFSPPPAYYTEVGKQLEIE--EVGHDPQVLAQHGILLDTDLHTDPSAQEASRENRRYLLQVFTKPIFAEDTFFLELIERRGATGFGEGNIKALWRSVQAYME 414
[Close]
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Planmine SMEST
Match: SMESG000056251.1 (SMESG000056251.1)

HSP 1 Score: 793.497 bits (2048), Expect = 0.000e+0
Identity = 383/383 (100.00%), Postives = 383/383 (100.00%), Query Frame = 1 
Query:   58 MGTTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 1206
            MGTTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL
Sbjct:    1 MGTTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQGLETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAFEVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFIDRSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVEWYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL 383
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Planmine SMEST
Match: SMESG000045752.1 (SMESG000045752.1)

HSP 1 Score: 96.2857 bits (238), Expect = 5.663e-22
Identity = 55/148 (37.16%), Postives = 86/148 (58.11%), Query Frame = 1 
Query:  790 PAAGKRKSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTE-DLDQLEKLSILIDFDD--------NG--YLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERG 1200
            P  G  K+QI E++  +   G+QHI ++ +DII A ++    G+ FL  P  YY  +++   + KI+  E  +D+ EK  IL+D +         NG  +L Q+FT  + DR T FLE+IQR    GFG+GN K+L++A+++ QE  G
Sbjct:  161 PGVGSGKNQINEFLMDHKGPGIQHIGLSVSDIIHATEISINNGVTFLKPPIGYYEIIKR---NPKIQTLEWCMDKFEKYGILVDAETEFSCSENTNGENFLYQVFTNPIFDRHTFFLELIQRQGATGFGSGNIKALWDAVDLSQESIG 305
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Planmine SMEST
Match: SMESG000037881.1 (SMESG000037881.1)

HSP 1 Score: 86.2705 bits (212), Expect = 4.027e-20
Identity = 49/128 (38.28%), Postives = 76/128 (59.38%), Query Frame = 1 
Query:  850 GVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTTLRKQLESAKIKVTE-DLDQLEKLSILIDFDD--------NG--YLLQIFTKNMQDRPTVFLEVIQRHNHNGFGAGNFKSLFEAIEVDQEERG 1200
            G+QHI ++ +DII A ++    G+ FL  P  YY  +++   + KI+  E  +D+ EK  IL+D +         NG  +L Q+FT  + DR T FLE+IQR    GFG+GN K+L++A+++ QE  G
Sbjct:    7 GIQHIGLSVSDIIHATEISINNGVIFLKPPTGYYEIIKR---NPKIQTLEWCMDKFEKYGILVDAETEFSCSENTNGKNFLYQVFTNPIFDRHTFFLELIQRQGATGFGSGNIKALWDAVDLSQESIG 131
The following BLAST results are available for this feature:
BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
HPD1.203e-17360.894-hydroxyphenylpyruvate dioxygenase [Source:HGNC S... [more]
HPD3.225e-15460.934-hydroxyphenylpyruvate dioxygenase [Source:HGNC S... [more]
HPDL3.317e-2625.414-hydroxyphenylpyruvate dioxygenase like [Source:H... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
hpd-14.775e-16657.594-hydroxyphenylpyruvate dioxygenase [Source:UniPr... [more]
C31H2.46.335e-9039.08pep chromosome:WBcel235:X:5155093:5159667:-1 gene:... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Hpd0.000e+065.35gene:FBgn0036992 transcript:FBtr0078225[more]
Hpd7.646e-14767.24gene:FBgn0036992 transcript:FBtr0078226[more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hpda2.237e-17663.124-hydroxyphenylpyruvate dioxygenase a [Source:NCBI... [more]
hpdb3.751e-17562.204-hydroxyphenylpyruvate dioxygenase b [Source:ZFIN... [more]
hpdb1.806e-17162.534-hydroxyphenylpyruvate dioxygenase b [Source:ZFIN... [more]
hpda5.070e-3656.414-hydroxyphenylpyruvate dioxygenase a [Source:NCBI... [more]
hpdl8.450e-3224.454-hydroxyphenylpyruvate dioxygenase-like [Source:Z... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hpd0.000e+064.40uncharacterized loc100125092 [Source:Xenbase;Acc:X... [more]
hpd0.000e+064.40uncharacterized loc100125092 [Source:Xenbase;Acc:X... [more]
hpd3.310e-17861.684-hydroxyphenylpyruvate dioxygenase [Source:NCBI g... [more]
hpd6.040e-17764.59uncharacterized loc100125092 [Source:Xenbase;Acc:X... [more]
hpd4.742e-17260.864-hydroxyphenylpyruvate dioxygenase [Source:NCBI g... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Hpd1.985e-17260.634-hydroxyphenylpyruvic acid dioxygenase [Source:MG... [more]
Hpd2.765e-4849.384-hydroxyphenylpyruvic acid dioxygenase [Source:MG... [more]
Hpd5.355e-3364.774-hydroxyphenylpyruvic acid dioxygenase [Source:MG... [more]
Hpdl3.679e-2623.594-hydroxyphenylpyruvate dioxygenase-like [Source:M... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5BKL0|HPPD_XENTR0.000e+064.404-hydroxyphenylpyruvate dioxygenase OS=Xenopus tro... [more]
sp|Q6TGZ5|HPPD_DANRE7.629e-17562.604-hydroxyphenylpyruvate dioxygenase OS=Danio rerio... [more]
sp|Q5EA20|HPPD_BOVIN1.503e-17461.684-hydroxyphenylpyruvate dioxygenase OS=Bos taurus ... [more]
sp|P32754|HPPD_HUMAN1.279e-17361.154-hydroxyphenylpyruvate dioxygenase OS=Homo sapien... [more]
sp|P49429|HPPD_MOUSE1.388e-17160.634-hydroxyphenylpyruvate dioxygenase OS=Mus musculu... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1QX220.000e+069.904-hydroxyphenylpyruvate dioxygenase OS=Crassostrea... [more]
A0A210PRQ40.000e+070.874-hydroxyphenylpyruvate dioxygenase OS=Mizuhopecte... [more]
A0A1I8IMR30.000e+069.84Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267H6020.000e+070.34Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267E0530.000e+069.47Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
hpda7.844e-17862.304-hydroxyphenylpyruvate dioxygenase [Source:NCBI g... [more]
hpdb1.058e-17462.244-hydroxyphenylpyruvate dioxygenase [Source:NCBI g... [more]
hpda9.679e-13652.484-hydroxyphenylpyruvate dioxygenase [Source:NCBI g... [more]
hpdl6.269e-2325.424-hydroxyphenylpyruvate dioxygenase-like [Source:Z... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000001974.11.885e-4569.31pep scaffold:Pmarinus_7.0:GL487872:2:2713:1 gene:E... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO352868.364e-3127.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
hpda2.243e-17863.354-hydroxyphenylpyruvate dioxygenase [Source:NCBI g... [more]
hpdb2.247e-14959.054-hydroxyphenylpyruvate dioxygenase-like [Source:N... [more]
hpda1.387e-14257.544-hydroxyphenylpyruvate dioxygenase [Source:NCBI g... [more]
hpdl2.334e-3527.414-hydroxyphenylpyruvate dioxygenase like [Source:N... [more]
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BLAST of 4-hydroxyphenylpyruvate dioxygenase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000056251.10.000e+0100.00SMESG000056251.1[more]
SMESG000045752.15.663e-2237.16SMESG000045752.1[more]
SMESG000037881.14.027e-2038.28SMESG000037881.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014546 ID=SMED30014546|Name=4-hydroxyphenylpyruvate dioxygenase|organism=Schmidtea mediterranea sexual|type=transcript|length=1302bp
TCTTCCGATCTGTTATAAACAGCGGTAACATTGCATTTAAAATTTGTCGC
GTACAAAATGGGAACTACTTATACGGATAAAGGTCCAAAGGTTGAAGCTG
GAAAATTCAAATCGTTTTATCAAATTACATTTTTGGTCGGAAATGCCAAA
CAAGCAGCCTCACATTATTGTGCTAGACTTGGTTTTACGGAATTCGCTTA
TCAAGGTCTTGAAACCGGAAATAGGGAAGTTGCAACTCACGTTGTTAAGC
AAAATGATATTATTTTTGCCTTTTCCAGCATGCTGCTTCCAAATAAACCG
AAAGAAATAGGAGAACACCTCACGGCCCATGGAGATGCAGTAAAAGATAT
AGCCTTTGAAGTAGAGGATTTAGATGCCATATTTCATAAAGCAGTTGAGA
AAGGAGCAAATGTTGTCAAAGATATTTGGACAGAAAGTGATGAGAACGGC
ACTGTGAAATTCGCGCGTATCAAAACATTTTATGACACAACTCATACCTT
TATCGATAGATCTCAATATAAAGGAGTTTATCTTCCGAATTATAGACTGA
TAAATGACGAAGACCCAATAAATAAAATTTTCGAATCACCTGGGCTAAAC
TTTATTGATCACATAGTAGGAAATCAGCCAGATGATCAAATGAATAATAT
TGTAGAATGGTATGAAAAGACTTTACAATTTCACCGATTTTGGTCAGTTG
ATGATTCCCAAATTCATACCGAATATTCAGCTCTGCGATCTATAGTCATC
ACGAATTACGATGAAACGGTAAAGTTGCCCATTAATGAACCAGCTGCGGG
GAAAAGGAAAAGTCAAATTCAAGAATACGTTGATTATTATGGAAGTGGAG
GAGTGCAACACATCGCCATGAATACAAATGACATTATCAAAGCGATAAAA
GTACTCAAAGGTCGAGGACTGAAATTTCTGGATGCACCAAAGACATATTA
CACAACTCTACGGAAGCAATTAGAAAGTGCAAAAATTAAAGTAACAGAAG
ATTTGGACCAGTTGGAGAAATTGTCCATTCTCATTGACTTCGATGACAAC
GGTTATTTGTTACAAATATTTACGAAAAATATGCAAGATCGGCCGACTGT
GTTTTTAGAAGTTATTCAAAGGCATAATCATAATGGTTTTGGGGCCGGAA
ATTTCAAAAGTCTTTTTGAAGCTATTGAAGTTGATCAAGAAGAAAGAGGA
AATCTCTAAGTCGTAAAACAAGAAATTATTTTTTAACTTAGGACAATTTA
ATAGTAACAATTTTATTCTTAATATATTTTATTGATTTTTCTTCAAAAAA
AA
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protein sequence of SMED30014546-orf-1

>SMED30014546-orf-1 ID=SMED30014546-orf-1|Name=SMED30014546-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=384bp
MGTTYTDKGPKVEAGKFKSFYQITFLVGNAKQAASHYCARLGFTEFAYQG
LETGNREVATHVVKQNDIIFAFSSMLLPNKPKEIGEHLTAHGDAVKDIAF
EVEDLDAIFHKAVEKGANVVKDIWTESDENGTVKFARIKTFYDTTHTFID
RSQYKGVYLPNYRLINDEDPINKIFESPGLNFIDHIVGNQPDDQMNNIVE
WYEKTLQFHRFWSVDDSQIHTEYSALRSIVITNYDETVKLPINEPAAGKR
KSQIQEYVDYYGSGGVQHIAMNTNDIIKAIKVLKGRGLKFLDAPKTYYTT
LRKQLESAKIKVTEDLDQLEKLSILIDFDDNGYLLQIFTKNMQDRPTVFL
EVIQRHNHNGFGAGNFKSLFEAIEVDQEERGNL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000421tail
PLANA:0002075pigment cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR037523VOC
IPR0417354OHPhenylPyrv_dOase_C
IPR0417364OHPhenylPyrv_dOase_N
IPR029068Glyas_Bleomycin-R_OHBP_Dase
IPR004360Glyas_Fos-R_dOase_dom
IPR0059564OHPhenylPyrv_dOase
Vocabulary: biological process
TermDefinition
GO:0009072aromatic amino acid family metabolic process
GO:0055114oxidation-reduction process
GO:0006260DNA replication
GO:0032508DNA duplex unwinding
Vocabulary: molecular function
TermDefinition
GO:0016701oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:00038684-hydroxyphenylpyruvate dioxygenase activity
GO:0003678DNA helicase activity
GO:0005524ATP binding
GO:0051213dioxygenase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 302..322
NoneNo IPR availablePFAMPF13669Glyoxalase_4coord: 22..122
e-value: 1.4E-6
score: 28.5
NoneNo IPR availablePANTHERPTHR11959:SF124-HYDROXYPHENYLPYRUVATE DIOXYGENASEcoord: 4..383
IPR0059564-hydroxyphenylpyruvate dioxygenasePIRSFPIRSF0092834HPP_dioxygenasecoord: 6..383
e-value: 1.7E-133
score: 443.1
IPR0059564-hydroxyphenylpyruvate dioxygenaseTIGRFAMTIGR01263TIGR01263coord: 20..383
e-value: 8.2E-133
score: 441.2
IPR0059564-hydroxyphenylpyruvate dioxygenasePANTHERPTHR119594-HYDROXYPHENYLPYRUVATE DIOXYGENASEcoord: 4..383
IPR004360Glyoxalase/fosfomycin resistance/dioxygenase domainPFAMPF00903Glyoxalasecoord: 183..337
e-value: 1.6E-17
score: 63.9
IPR029068Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenaseGENE3DG3DSA:3.10.180.10coord: 2..176
e-value: 3.8E-53
score: 181.7
IPR029068Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenaseGENE3DG3DSA:3.10.180.10coord: 179..383
e-value: 4.8E-86
score: 289.6
IPR029068Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenaseSUPERFAMILYSSF54593Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenasecoord: 16..370
IPR037523Vicinal oxygen chelate (VOC) domainPROSITEPS51819VOCcoord: 182..340
score: 22.896
IPR037523Vicinal oxygen chelate (VOC) domainPROSITEPS51819VOCcoord: 19..151
score: 22.3
IPR0417354-hydroxyphenylpyruvate dioxygenase, C-terminalCDDcd07250HPPD_C_likecoord: 180..374
e-value: 2.39801E-113
score: 326.82
IPR0417364-hydroxyphenylpyruvate dioxygenase, N-terminalCDDcd08342HPPD_N_likecoord: 23..163
e-value: 6.17042E-59
score: 185.876