Protein VAC14 homolog

Overview
NameProtein VAC14 homolog
Smed IDSMED30014485
Length (bp)2672
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein VAC14 homolog (SMED30014485) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein VAC14 homolog (SMED30014485) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein VAC14 homolog (SMED30014485) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein VAC14 homolog (SMED30014485) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014485

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30014485h1SMcG0016809 Contig4299GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014485h1SMcG0023123 Contig4299GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30014485h1SMcG0023123 dd_Smed_v4_4616_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014485h1SMcG0023123 dd_Smed_v4_4616_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014485h1SMcG0023123 Contig4059GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Human
Match: VAC14 (VAC14 component of PIKFYVE complex [Source:HGNC Symbol;Acc:HGNC:25507])

HSP 1 Score: 396.741 bits (1018), Expect = 1.006e-124
Identity = 248/729 (34.02%), Postives = 401/729 (55.01%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSG-KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLEL--------------------------TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ S +  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    + +L  FL ++  +   + +  + NILV  I+  +  ++I  TA+ W+  FI+     MLP++S IL A+LP    D + + I+  A   +  L++LV   D           Q+  P P   L   E  +    + + D   S   + V    + + +P   +   + + L+  C  S       T++A L+WL+ L      +    +++LFP L++ + D S  VI   L ++A+ +        + ++   L  PD   +  EL                          T N YF KF  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +VH LN ILL++  L   R  +K + + ES N+FC LYR+W +N V  +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D + +  L + LYGLLML+PQS AF++L +RL C+P  ++
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVSFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILV--IHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDELDELRPGQRQAE-PTPDDALPKQEGTASGGPDGSCDSSFSSGIS-VFTAASTERAPVTLHLDGIVQVLN--CHLSDTAIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPA---GQTDDPGPLDGPDLQASHSELQVPTPGRAGLLNTSGTKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPEL 725
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Human
Match: VAC14 (VAC14 component of PIKFYVE complex [Source:HGNC Symbol;Acc:HGNC:25507])

HSP 1 Score: 149.058 bits (375), Expect = 2.934e-40
Identity = 74/157 (47.13%), Postives = 107/157 (68.15%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMR 603
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLK 162
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Human
Match: VAC14 (VAC14 component of PIKFYVE complex [Source:HGNC Symbol;Acc:HGNC:25507])

HSP 1 Score: 144.821 bits (364), Expect = 1.258e-38
Identity = 70/157 (44.59%), Postives = 105/157 (66.88%), Query Frame = 1 
Query: 1768 FAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
             A+I+ + + L+    +VH LN ILL++  L   R  +K + + ES N+FC LYR+W +N V  +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D + +  L + LYGLLML+PQS AF++L +RL C+P  ++
Sbjct:    1 MADILLREEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPEL 157
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Human
Match: VAC14 (VAC14 component of PIKFYVE complex [Source:HGNC Symbol;Acc:HGNC:25507])

HSP 1 Score: 120.939 bits (302), Expect = 6.457e-30
Identity = 69/204 (33.82%), Postives = 110/204 (53.92%), Query Frame = 1 
Query: 1627 TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            T N YF KF  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +VH LN ILL++  L   R  +K +                             T NY H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D + +  L + LYGLLML+PQS AF++L +RL C+P  ++
Sbjct:   66 TMNSYFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHALNTILLTSTELFQLRNQLKDLK----------------------------TLNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPEL 241
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Human
Match: VAC14 (VAC14 component of PIKFYVE complex [Source:HGNC Symbol;Acc:HGNC:25507])

HSP 1 Score: 45.0542 bits (105), Expect = 8.101e-6
Identity = 23/41 (56.10%), Postives = 30/41 (73.17%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKT 255
            ++ PLT NIVR L+DKLYEKRK AA++IE+      +QG T
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEK------TQGST 40
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Celegans
Match: vacl-14 (VAC (Yeast VACuole morphology)-Like [Source:UniProtKB/TrEMBL;Acc:Q21225])

HSP 1 Score: 172.17 bits (435), Expect = 1.907e-44
Identity = 104/313 (33.23%), Postives = 177/313 (56.55%), Query Frame = 1 
Query:  124 MTD-EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALG-KQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYR---RLVNILVFQI--NNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILP 1041
            M+D +Y P++  I+R++ DK YE+RK+AA+D+E+LV+   +  +  ++   +   GE    S N + RKGG IG+AA +IALG K A  + + ++ P I    D D ++RYYACESLYN  K+   +VL +F+ IFD L +   D+D++VR     L++ + E+V++    D+A +++ +RD+IY  ++  R F++ W+ ++D         Y+ EI DGL  ML +    + +  + +L NFL  + S    L      +++N+LV     N P  +      +L+W+  F++ +K  +L   S  L  ILP
Sbjct:    1 MSDGQYGPISAGIIRSITDKSYERRKAAALDVEKLVRDLFNNNQLSQLDKCLSVLGE-LINSGNSNQRKGGLIGMAAASIALGNKNAPPYTAKLVEPIIPCFHDADLQIRYYACESLYNIAKICKTSVLAHFEDIFDVLWRVTADSDQNVRGGAELLNRLITEIVLSEQEFDIAILMSLIRDRIYTQTSSNRRFILEWLNTIDSAPFFSFCNYISEISDGLFKMLGEQAPAVRDLCETVLGNFLTAIRSKPESLSLEDRIQMINVLVVHTHENEPFLA---RKLSLIWLEEFVKLYKTDLLVMLSTCLVGILP 309

HSP 2 Score: 129.413 bits (324), Expect = 1.219e-30
Identity = 87/304 (28.62%), Postives = 155/304 (50.99%), Query Frame = 1 
Query: 1327 LSETLHILCEFSGKYSQQTKLAALEW---LHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKD-VPLYSEINNSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            L +T+ +L ++      +T++  L W   LH+ M   L   +H    +FP L+  + D S  V+   L L++   + +  P   +++ S F     ++K V  ++  P+ +KF   L+    T+  +L E+  LII  LC  L P  ++     ++++         +V  L+ +LL+   L   R  ++++ ++ S ++F  ++R WS   +ALL LCLL+Q+Y+    +       ++ V+ L EID L+  +E+PV A++RM L+   +   L   L  LLML+PQSEAF  L  RL  +P
Sbjct:  339 LDKTIEVLLKYIKYDVVETRVTVLNWIRHLHSSMPGQLFVHMH---QIFPVLLNTLSDTSDEVLLLDLFLISNICQSESAP--DQVDVSTFGLNETELKQVSHIS--PFLIKFVLSLLEMFRTEPTLLRERGVLIIRQLCLLLEPAHIYRVICVLLERESKHNFAQEMVSTLHGVLLTATELFILRDELRALSNESSRSLFECIFRVWSNRPIALLGLCLLSQHYQQAADIALLLSQVDITVDVLLEIDKLVNLVESPVLAYVRMDLLSSIHRPPLCTVLSALLMLLPQSEAFVTLHKRLQAVP 635
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Fly
Match: CG5608 (gene:FBgn0038058 transcript:FBtr0082680)

HSP 1 Score: 304.679 bits (779), Expect = 1.844e-91
Identity = 212/708 (29.94%), Postives = 360/708 (50.85%), Query Frame = 1 
Query:  124 MTDEYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDH-LDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEH-IRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEII-QKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAA----LSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            M   Y PL+ +  + L DK+YEKRK A+ +IE++V ++ ++  + +I  +I+     + TS + + RKG  IGLAA+ + LGK + ++   ++ P +  L DPD RVRY+ACESLYN +KV    ++P+F  +F AL++   D+D+ V+     LD+ ++++V  S    ++ + +  LR+ IY     AR ++I+WI+ L+    + MV YL EILDGL +ML D+   +    +  ++ FL  + +    +     +N L+    +P  + +I   A+ WI  F++ F   +LP+ S I  AILP  + + + +  I+  A +V+  ++ LV T +    T ++                                  +D   +  +++Q L+                       S  TK+A L+W+H L      +    +  L  +L+  + D S  V+   L ++A           EI NS       Q    L      ++ KF   L+     +  +LE +  LII  LC  L    ++ TFAEII + + +L+    +V  LN ILL++  L   R  +++I +++S ++F  LY++W++  V+ LSLCLLTQ+Y+H  RL+  F D E+ +  L E D L+Q +E+P+FA LR+ L+    + A    L+  L+G+LML+PQ+EAF  L NRL C+P
Sbjct:    1 MEPPYAPLSESCAKALGDKVYEKRKLASQEIEKMVTEFNNKNNSAQIRKLIEVLATDYATSRDANRRKGALIGLAAMGLGLGKDSGKYVQGMVTPIMTCLSDPDIRVRYFACESLYNVVKVARSAIIPFFPELFAALSRLVTDSDQMVKDGSELLDRLLKDIVTESSQTFNLQAFIPLLREHIYVKDAFARQYVISWISILNAVPDINMVNYLTEILDGLFVMLEDNTLEIQRMCETTISQFLKSIRNDSSSVRMEDTINTLITHAQSP--NELIKSIAITWIREFVQIFGPNVLPYASGIFTAILPCLEYNVESKRSIKECAVSVNNSMMLLVSTKELKTETVAK----------------------------------IDLRSIMDVLSQYLT---------------------HNSMHTKIAVLKWIHHLFTNFPNEMSVHASNLNTNLLSTLADNSDEVVLQSLSVLA-----------EIVNS-------QESRELNDFNKSHYRKFLLSLLNLFSEEKLILENRASLIIRKLCVLLNAEYIYRTFAEIIAEGVPNLKFASTVVRLLNMILLTSTELFELRTSLRNISNEKSADLFQCLYKSWAHCPVSTLSLCLLTQSYQHVSRLVTLFADVEITLELLTEFDKLVQLIESPIFAPLRLTLVSKANNCADAQYLAHALFGILMLLPQTEAFDTLRNRLQCVP 633
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Zebrafish
Match: vac14 (vac14 homolog (S. cerevisiae) [Source:NCBI gene;Acc:447912])

HSP 1 Score: 399.053 bits (1024), Expect = 5.021e-126
Identity = 253/727 (34.80%), Postives = 412/727 (56.67%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVF--QINNPSCS--NIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSG------------KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFS-----KKDVPLYSEINNSDF-LTVPDQIKNVLELTE---NPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  + +I  +I+     F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ + V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L DS + +    + +L  FL ++  +   + +  + NILV   Q+++ S S  ++I  T++ W+  FI+     +LP++S IL A+LP    D + +  +  A   +  L++LV   D  D   S+   +S+PP        +E PS    +  GD   S++ +Q     +   S    +  A S+   +  +  G                 T++A L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +     + D     +I++S   L +P      L  +    N YF KF  +L++    + ++LE +   II  LC  L    +F++ A+I+ K + L+    +V  LN ILL++  L   R  +K + ++ESC +FC LYR+W +N VA +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E+P+F +LR+ L+D  ++  L + LYGLLML+PQS+AF++L +RL+C+P  ++
Sbjct:    6 DFSPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNSAQIRHVIQILATEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIDPVLTCFNDSDSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVAFVPLLRERIYSNNQYARQFIISWIHVLESVPDINLLDYLPEILDGLFQILGDSSKEIRRMCELVLGEFLKEIKKNPSSVKFAEMANILVIHCQVSDESKSTNDLIQLTSMTWMREFIQLAGRVVLPYSSGILTAVLPCLSYDDRKKSTKEAASACNHSLMKLVTPEDDEDDEESQT--KSSPPS-------DEAPS----KKEGDLNDSLNESQE----SVGFSNISFFTPASSDRSAVTLDLDGIVQVLDRHLHDSSTGMMTRIAVLKWLYHLYIKTPRKMFKHTDSLFPMLLKTLSDESDEVILKDLEVLAEIASSPAGQTDTSGSCDISDSKTELHIPGSKMTDLSPSTPSMNSYFYKFMINLLKRFSLERKLLEMRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMVQTLNTILLTSAELFQLRNQLKDLRTQESCALFCCLYRSWCHNPVATVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLMEVDKLVQLIESPIFTYLRLQLLDVEHNPYLIKALYGLLMLLPQSQAFQLLSHRLSCVPNPEL 715
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Zebrafish
Match: vac14 (vac14 homolog (S. cerevisiae) [Source:NCBI gene;Acc:447912])

HSP 1 Score: 397.127 bits (1019), Expect = 3.621e-125
Identity = 252/738 (34.15%), Postives = 415/738 (56.23%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVF--QINNPSCS--NIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSG------------KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFS-----KKDVPLYSEINNSDF-LTVPDQIKNVLEL--------------TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  + +I  +I+     F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ + V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L DS + +    + +L  FL ++  +   + +  + NILV   Q+++ S S  ++I  T++ W+  FI+     +LP++S IL A+LP    D + +  +  A   +  L++LV   D  D   S+   +S+PP        +E PS    +  GD   S++ +Q     +   S    +  A S+   +  +  G                 T++A L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +     + D     +I++S   L +P  +++   +              + N YF KF  +L++    + ++LE +   II  LC  L    +F++ A+I+ K + L+    +V  LN ILL++  L   R  +K + ++ESC +FC LYR+W +N VA +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E+P+F +LR+ L+D  ++  L + LYGLLML+PQS+AF++L +RL+C+P  ++
Sbjct:    6 DFSPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNSAQIRHVIQILATEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIDPVLTCFNDSDSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVAFVPLLRERIYSNNQYARQFIISWIHVLESVPDINLLDYLPEILDGLFQILGDSSKEIRRMCELVLGEFLKEIKKNPSSVKFAEMANILVIHCQVSDESKSTNDLIQLTSMTWMREFIQLAGRVVLPYSSGILTAVLPCLSYDDRKKSTKEAASACNHSLMKLVTPEDDEDDEESQT--KSSPPS-------DEAPS----KKEGDLNDSLNESQE----SVGFSNISFFTPASSDRSAVTLDLDGIVQVLDRHLHDSSTGMMTRIAVLKWLYHLYIKTPRKMFKHTDSLFPMLLKTLSDESDEVILKDLEVLAEIASSPAGQTDTSGSCDISDSKTELHIPGGVRDGQPVVVGSKMTDLSPSTPSMNSYFYKFMINLLKRFSLERKLLEMRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMVQTLNTILLTSAELFQLRNQLKDLRTQESCALFCCLYRSWCHNPVATVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLMEVDKLVQLIESPIFTYLRLQLLDVEHNPYLIKALYGLLMLLPQSQAFQLLSHRLSCVPNPEL 726
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Xenopus
Match: vac14 (Vac14 homolog [Source:NCBI gene;Acc:100216224])

HSP 1 Score: 407.142 bits (1045), Expect = 3.874e-129
Identity = 255/721 (35.37%), Postives = 405/721 (56.17%), Query Frame = 1 
Query:  142 PLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEEN-TGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCE--FSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINN-SDFLT--------VPD---QIKNVLEL-----------TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            PLT NIVR L+DK+YEKRK AA++IE+LV+++ SQ  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK + ++   +I P +    D D+R+RYYACE+LYN +KV  G+VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+   V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    +  L  FL ++      + +  + NILV  I+  S  ++I  TA+ W+  F++     MLP++S IL A+LP    D + ++I+  A   +  L++L+   D       ++TD           DV ++P+   +E+ + +HE     N  +Q  N   SP     L L   +H+L            T++  L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +        ++ + +D  T        VP+   Q  N  EL           T N YF +F  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +V  LN ILL++  L   R+ +K + + ESCN+FC LYR+W +N VA +SLC LTQNY+H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D      L   LYGLLML+PQS AF++L +RL C+P
Sbjct:    9 PLTPNIVRALNDKMYEKRKVAALEIEKLVREFVSQNNTAQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGQYLRELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVSLGEFLKEIKKLPDSVKFAEMANILV--IHCQSTDDLIQLTAMTWMREFLQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLITPED-------DETD-----------DVRQSPATQPDEDLSSNHE-----NSSQQTSNN--SPV---SLNLDGIVHVLDRHLHESTTGMMTRICVLKWLYHLYIKTPRKMFRHTDSLFPILLKTLSDESDEVILKDLEVLAEIASSPAGQTDKMTDCTDLPTGVSELHVPVPNKVAQAHNSGELIRGLECSPSTPTMNSYFHRFMINLLKRFSSERKLLETRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVQNLNSILLTSSELFQLRSQLKDLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHAYHLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENHPYLIRALYGLLMLLPQSSAFQLLSHRLQCVP 699
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Xenopus
Match: vac14 (Vac14 homolog [Source:NCBI gene;Acc:100216224])

HSP 1 Score: 406.757 bits (1044), Expect = 6.028e-129
Identity = 252/730 (34.52%), Postives = 407/730 (55.75%), Query Frame = 1 
Query:  142 PLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEEN-TGDHELSVDPNQVKQIINQKLSPFPT--YGLALSETLHILCE--FSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINN-SDFLT--------VPDQIKNV-------LEL-----TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDIAGLIP 2253
            PLT NIVR L+DK+YEKRK AA++IE+LV+++ SQ  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK + ++   +I P +    D D+R+RYYACE+LYN +KV  G+VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+   V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    +  L  FL ++      + +  + NILV  I+  S  ++I  TA+ W+  F++     MLP++S IL A+LP    D + ++I+  A   +  L++L+   D       ++TD           DV ++P+   +E+ + +HE S          +  +S F +    L L   +H+L            T++  L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +        ++ + +D  T        VP+++          LE      T N YF +F  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +V  LN ILL++  L   R+ +K + + ESCN+FC LYR+W +N VA +SLC LTQNY+H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D      L   LYGLLML+PQS AF++L +RL C+P    +   P
Sbjct:    9 PLTPNIVRALNDKMYEKRKVAALEIEKLVREFVSQNNTAQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGQYLRELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVSLGEFLKEIKKLPDSVKFAEMANILV--IHCQSTDDLIQLTAMTWMREFLQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLITPED-------DETD-----------DVRQSPATQPDEDLSSNHENSSQQTSNNSKFHLLISVFTSCPVSLNLDGIVHVLDRHLHESTTGMMTRICVLKWLYHLYIKTPRKMFRHTDSLFPILLKTLSDESDEVILKDLEVLAEIASSPAGQTDKMTDCTDLPTGVSELHVPVPNKVAQAHNSVIRGLECSPSTPTMNSYFHRFMINLLKRFSSERKLLETRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVQNLNSILLTSSELFQLRSQLKDLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHAYHLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENHPYLIRALYGLLMLLPQSSAFQLLSHRLQCVPNPQASKEAP 718
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Xenopus
Match: vac14 (Vac14 homolog [Source:NCBI gene;Acc:100216224])

HSP 1 Score: 406.757 bits (1044), Expect = 9.611e-129
Identity = 251/723 (34.72%), Postives = 404/723 (55.88%), Query Frame = 1 
Query:  142 PLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEEN-TGDHELSVDPNQVKQIINQKLSPFPTY----GLALSETLHILCE--FSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINN-SDFLT--------VPDQIKNV-------LEL-----TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            PLT NIVR L+DK+YEKRK AA++IE+LV+++ SQ  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK + ++   +I P +    D D+R+RYYACE+LYN +KV  G+VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+   V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    +  L  FL ++      + +  + NILV  I+  S  ++I  TA+ W+  F++     MLP++S IL A+LP    D + ++I+  A   +  L++L+   D       ++TD           DV ++P+   +E+ + +HE S          +  +    TY     L L   +H+L            T++  L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +        ++ + +D  T        VP+++          LE      T N YF +F  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +V  LN ILL++  L   R+ +K + + ESCN+FC LYR+W +N VA +SLC LTQNY+H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D      L   LYGLLML+PQS AF++L +RL C+P
Sbjct:    9 PLTPNIVRALNDKMYEKRKVAALEIEKLVREFVSQNNTAQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGQYLRELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVSLGEFLKEIKKLPDSVKFAEMANILV--IHCQSTDDLIQLTAMTWMREFLQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLITPED-------DETD-----------DVRQSPATQPDEDLSSNHENSSQQTSNNSKFHLLICTLSTYHGPVSLNLDGIVHVLDRHLHESTTGMMTRICVLKWLYHLYIKTPRKMFRHTDSLFPILLKTLSDESDEVILKDLEVLAEIASSPAGQTDKMTDCTDLPTGVSELHVPVPNKVAQAHNSVIRGLECSPSTPTMNSYFHRFMINLLKRFSSERKLLETRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVQNLNSILLTSSELFQLRSQLKDLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHAYHLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENHPYLIRALYGLLMLLPQSSAFQLLSHRLQCVP 711
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Xenopus
Match: vac14 (Vac14 homolog [Source:NCBI gene;Acc:100216224])

HSP 1 Score: 406.371 bits (1043), Expect = 1.423e-128
Identity = 248/718 (34.54%), Postives = 399/718 (55.57%), Query Frame = 1 
Query:  142 PLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCE--FSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINN-SDFLT--------VPDQIKNV-------LEL-----TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            PLT NIVR L+DK+YEKRK AA++IE+LV+++ SQ  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK + ++   +I P +    D D+R+RYYACE+LYN +KV  G+VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+   V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    +  L  FL ++      + +  + NILV  I+  S  ++I  TA+ W+  F++     MLP++S IL A+LP    D + ++I+  A   +  L++L+   D       E  D    P      D++ N   S ++ + + +       V +     +   P   L L   +H+L            T++  L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +        ++ + +D  T        VP+++          LE      T N YF +F  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +V  LN ILL++  L   R+ +K + + ESCN+FC LYR+W +N VA +SLC LTQNY+H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D      L   LYGLLML+PQS AF++L +RL C+P
Sbjct:    9 PLTPNIVRALNDKMYEKRKVAALEIEKLVREFVSQNNTAQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGQYLRELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVSLGEFLKEIKKLPDSVKFAEMANILV--IHCQSTDDLIQLTAMTWMREFLQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLITPED------DETDDVRQSPATQPDEDLSSNHENSSQQTSNNSKFHFIGGSVVEFSPATMHTGPV-SLNLDGIVHVLDRHLHESTTGMMTRICVLKWLYHLYIKTPRKMFRHTDSLFPILLKTLSDESDEVILKDLEVLAEIASSPAGQTDKMTDCTDLPTGVSELHVPVPNKVAQAHNSVIRGLECSPSTPTMNSYFHRFMINLLKRFSSERKLLETRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVQNLNSILLTSSELFQLRSQLKDLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHAYHLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENHPYLIRALYGLLMLLPQSSAFQLLSHRLQCVP 717
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Xenopus
Match: vac14 (Vac14 homolog [Source:NCBI gene;Acc:100216224])

HSP 1 Score: 405.216 bits (1040), Expect = 4.261e-128
Identity = 253/723 (34.99%), Postives = 405/723 (56.02%), Query Frame = 1 
Query:  142 PLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEEN-TGDHELSVD--PNQVKQIINQKLSPFPT--YGLALSETLHILCE--FSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINN-SDFLT--------VPDQIKNV-------LEL-----TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            PLT NIVR L+DK+YEKRK AA++IE+LV+++ SQ  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK + ++   +I P +    D D+R+RYYACE+LYN +KV  G+VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+   V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    +  L  FL ++      + +  + NILV  I+  S  ++I  TA+ W+  F++     MLP++S IL A+LP    D + ++I+  A   +  L++L+   D       ++TD           DV ++P+   +E+ + +HE S     N  K    Q+     T    L L   +H+L            T++  L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +        ++ + +D  T        VP+++          LE      T N YF +F  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +V  LN ILL++  L   R+ +K + + ESCN+FC LYR+W +N VA +SLC LTQNY+H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D      L   LYGLLML+PQS AF++L +RL C+P
Sbjct:    9 PLTPNIVRALNDKMYEKRKVAALEIEKLVREFVSQNNTAQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGQYLRELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVSLGEFLKEIKKLPDSVKFAEMANILV--IHCQSTDDLIQLTAMTWMREFLQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLITPED-------DETD-----------DVRQSPATQPDEDLSSNHENSSQQTSNNSKCSEEQRNGGMHTGPVSLNLDGIVHVLDRHLHESTTGMMTRICVLKWLYHLYIKTPRKMFRHTDSLFPILLKTLSDESDEVILKDLEVLAEIASSPAGQTDKMTDCTDLPTGVSELHVPVPNKVAQAHNSVIRGLECSPSTPTMNSYFHRFMINLLKRFSSERKLLETRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVQNLNSILLTSSELFQLRSQLKDLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHAYHLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENHPYLIRALYGLLMLLPQSSAFQLLSHRLQCVP 711
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Mouse
Match: Vac14 (Vac14 homolog (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2157980])

HSP 1 Score: 399.053 bits (1024), Expect = 8.936e-126
Identity = 253/735 (34.42%), Postives = 401/735 (54.56%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTM-DHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYG-------LALSETLHIL-CEFSG-KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFS-----KKDVPLYSE-----INNSDFLTVPDQIKNVLE-------------LTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+ + +Q  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S   D+ S +  LR++IY ++  AR F+I+WI  L     + ++ YLPEILDGL  +L D+ + +    + +L  FL ++  +   + +  + NILV  I+  +  ++I  TA+ W+  FI+     MLP++S IL A+LP    D + + I+  A   +  L++LV    D  D   S    Q+ P           NP  SL +  G    S  P          ++ F +         L L   + +L C  S       T++A L+WL+ L      +    +++LFP L++ + D S  V+   L ++A+ +     + D P   +     +N+S+         N+L               T N YF KF  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +VH LN ILL++  L   R  +K + + ES N+FC LYR+W +N V  +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D + +  L + LYGLLML+PQS AF++L +RL C+P  ++
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEKLVRDFVAQNNTMQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESSKFDLVSFIPLLRERIYSNNQYARQFIISWILVLVSVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILV--IHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKSVAQKQTEP-----------NPEDSLPKQEG--TASGGPGSCDSSFGSGINVFTSANTDRAPVTLHLDGIVQVLNCHLSDTTIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVVLKDLEVLAEIASSPAGQTDDPGAPDGPDLRVNHSELQVPTSGRANLLNPPSTKGLEGSPSTPTMNSYFYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSTELFQLRNQLKDLQTPESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPEL 725
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Mouse
Match: Vac14 (Vac14 homolog (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2157980])

HSP 1 Score: 243.047 bits (619), Expect = 5.141e-71
Identity = 161/471 (34.18%), Postives = 253/471 (53.72%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTM-DHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYG-------LALSETLHIL-CEFSG-KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRA 1515
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+ + +Q  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S   D+ S +  LR++IY ++  AR F+I+WI  L     + ++ YLPEILDGL  +L D+ + +    + +L  FL ++  +   + +  + NILV  I+  +  ++I  TA+ W+  FI+     MLP++S IL A+LP    D + + I+  A   +  L++LV    D  D   S    Q+ P           NP  SL +  G    S  P          ++ F +         L L   + +L C  S       T++A L+WL+ L      +    +++LFP L++ + D S  V +A
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEKLVRDFVAQNNTMQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESSKFDLVSFIPLLRERIYSNNQYARQFIISWILVLVSVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILV--IHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKSVAQKQTEP-----------NPEDSLPKQEG--TASGGPGSCDSSFGSGINVFTSANTDRAPVTLHLDGIVQVLNCHLSDTTIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVPKA 461
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Mouse
Match: Vac14 (Vac14 homolog (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2157980])

HSP 1 Score: 137.117 bits (344), Expect = 3.940e-37
Identity = 67/134 (50.00%), Postives = 93/134 (69.40%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDAL 534
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+ + +Q  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEKLVRDFVAQNNTMQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGL 139
[Close]
BLAST of Protein VAC14 homolog vs. UniProt/SwissProt
Match: sp|Q68F38|VAC14_XENLA (Protein VAC14 homolog OS=Xenopus laevis OX=8355 GN=vac14 PE=2 SV=1)

HSP 1 Score: 400.208 bits (1027), Expect = 2.370e-125
Identity = 255/726 (35.12%), Postives = 403/726 (55.51%), Query Frame = 1 
Query:  142 PLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIIN----QKLSPFPTYGLALSETLHILCE--FSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKK------------DVPL-YSEINNSDFLTVPDQIKNV-------LEL-----TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            PLT NIVR L+DK+YEKRK AA++IE+LV+++ SQ  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK + ++   +I P +    D D+R+RYYACE+LYN +KV  G+VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S   D+   V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    +  L  FL ++      + +  + NILV  I+  S  ++I  TA+ W+  F++     MLP++S IL A+LP    D + ++I+  A   +  L++L+   D  D T  ++  QS    P    D + N   S +  T +  L   P+      N      ++  P   L L   +H+L            T++  L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +              D+P   SE++    + VP ++          LE      T N YF +F  +L++    + ++LE +   II  LC  L    +F++ A+I+ + + L+    +V  LN ILL++  L   R+ +K + + ESCN+FC LYR+W +N VA +SLC LTQNY+H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D   +  L   LYGLLML+PQS AF++L +RL C+P
Sbjct:    9 PLTPNIVRALNDKMYEKRKVAALEIEKLVREFVSQNNTAQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGQYLRELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESSKFDLVGFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVSLGEFLKEIKKLPDSVKFAEMANILV--IHCQSTDDLIQLTAMTWMREFLQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLITPED--DET--DEVRQSPATQPDE--DFSSNHENSSQHTTYNRTLPSAPDSSLDNANIFAPSSMNTCPV-SLNLDGIVHVLDRHLHESTTGMMTRICVLKWLYHLYIKTPRKMFRHTDSLFPILLKTLSDESDEVILKDLEVLAEIASSPAGQTDIVTDCNDLPTGMSELH----VPVPTKVTQAHGSVIRGLECSPSTPTMNSYFHRFMVNLLKRFSNERKLLEIRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVQNLNSILLTSSELFQLRSQLKDLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHAYNLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENNPYLIRALYGLLMLLPQSSAFQLLSHRLQCVP 721
[Close]
BLAST of Protein VAC14 homolog vs. UniProt/SwissProt
Match: sp|Q66L58|VAC14_DANRE (Protein VAC14 homolog OS=Danio rerio OX=7955 GN=vac14 PE=2 SV=1)

HSP 1 Score: 399.053 bits (1024), Expect = 3.790e-125
Identity = 253/727 (34.80%), Postives = 412/727 (56.67%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVF--QINNPSCS--NIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSG------------KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFS-----KKDVPLYSEINNSDF-LTVPDQIKNVLELTE---NPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  + +I  +I+     F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ + V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L DS + +    + +L  FL ++  +   + +  + NILV   Q+++ S S  ++I  T++ W+  FI+     +LP++S IL A+LP    D + +  +  A   +  L++LV   D  D   S+   +S+PP        +E PS    +  GD   S++ +Q     +   S    +  A S+   +  +  G                 T++A L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +     + D     +I++S   L +P      L  +    N YF KF  +L++    + ++LE +   II  LC  L    +F++ A+I+ K + L+    +V  LN ILL++  L   R  +K + ++ESC +FC LYR+W +N VA +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E+P+F +LR+ L+D  ++  L + LYGLLML+PQS+AF++L +RL+C+P  ++
Sbjct:    6 DFSPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNSAQIRHVIQILATEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIDPVLTCFNDSDSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVAFVPLLRERIYSNNQYARQFIISWIHVLESVPDINLLDYLPEILDGLFQILGDSSKEIRRMCELVLGEFLKEIKKNPSSVKFAEMANILVIHCQVSDESKSTNDLIQLTSMTWMREFIQLAGRVVLPYSSGILTAVLPCLSYDDRKKSTKEAASACNHSLMKLVTPEDDEDDEESQT--KSSPPS-------DEAPS----KKEGDLNDSLNESQE----SVGFSNISFFTPASSDRSAVTLDLDGIVQVLDRHLHDSSTGMMTRIAVLKWLYHLYIKTPRKMFKHTDSLFPMLLKTLSDESDEVILKDLEVLAEIASSPAGQTDTSGSCDISDSKTELHIPGSKMTDLSPSTPSMNSYFYKFMINLLKRFSLERKLLEMRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMVQTLNTILLTSAELFQLRNQLKDLRTQESCALFCCLYRSWCHNPVATVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLMEVDKLVQLIESPIFTYLRLQLLDVEHNPYLIKALYGLLMLLPQSQAFQLLSHRLSCVPNPEL 715
[Close]
BLAST of Protein VAC14 homolog vs. UniProt/SwissProt
Match: sp|Q80WQ2|VAC14_MOUSE (Protein VAC14 homolog OS=Mus musculus OX=10090 GN=Vac14 PE=1 SV=1)

HSP 1 Score: 399.053 bits (1024), Expect = 6.251e-125
Identity = 253/735 (34.42%), Postives = 401/735 (54.56%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTM-DHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYG-------LALSETLHIL-CEFSG-KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFS-----KKDVPLYSE-----INNSDFLTVPDQIKNVLE-------------LTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+ + +Q  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S   D+ S +  LR++IY ++  AR F+I+WI  L     + ++ YLPEILDGL  +L D+ + +    + +L  FL ++  +   + +  + NILV  I+  +  ++I  TA+ W+  FI+     MLP++S IL A+LP    D + + I+  A   +  L++LV    D  D   S    Q+ P           NP  SL +  G    S  P          ++ F +         L L   + +L C  S       T++A L+WL+ L      +    +++LFP L++ + D S  V+   L ++A+ +     + D P   +     +N+S+         N+L               T N YF KF  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +VH LN ILL++  L   R  +K + + ES N+FC LYR+W +N V  +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D + +  L + LYGLLML+PQS AF++L +RL C+P  ++
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEKLVRDFVAQNNTMQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESSKFDLVSFIPLLRERIYSNNQYARQFIISWILVLVSVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILV--IHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDEPDEPKSVAQKQTEP-----------NPEDSLPKQEG--TASGGPGSCDSSFGSGINVFTSANTDRAPVTLHLDGIVQVLNCHLSDTTIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVVLKDLEVLAEIASSPAGQTDDPGAPDGPDLRVNHSELQVPTSGRANLLNPPSTKGLEGSPSTPTMNSYFYKFMINLLQTFSSERKLLEARGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHTLNTILLTSTELFQLRNQLKDLQTPESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPEL 725
[Close]
BLAST of Protein VAC14 homolog vs. UniProt/SwissProt
Match: sp|Q08AM6|VAC14_HUMAN (Protein VAC14 homolog OS=Homo sapiens OX=9606 GN=VAC14 PE=1 SV=1)

HSP 1 Score: 396.741 bits (1018), Expect = 4.829e-124
Identity = 248/729 (34.02%), Postives = 401/729 (55.01%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSG-KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLEL--------------------------TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ S +  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    + +L  FL ++  +   + +  + NILV  I+  +  ++I  TA+ W+  FI+     MLP++S IL A+LP    D + + I+  A   +  L++LV   D           Q+  P P   L   E  +    + + D   S   + V    + + +P   +   + + L+  C  S       T++A L+WL+ L      +    +++LFP L++ + D S  VI   L ++A+ +        + ++   L  PD   +  EL                          T N YF KF  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +VH LN ILL++  L   R  +K + + ES N+FC LYR+W +N V  +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D + +  L + LYGLLML+PQS AF++L +RL C+P  ++
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVSFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKEIKKNPSSVKFAEMANILV--IHCQTTDDLIQLTAMCWMREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKKSIKEVANVCNQSLMKLVTPEDDELDELRPGQRQAE-PTPDDALPKQEGTASGGPDGSCDSSFSSGIS-VFTAASTERAPVTLHLDGIVQVLN--CHLSDTAIGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLQTLSDESDEVILKDLEVLAEIASSPA---GQTDDPGPLDGPDLQASHSELQVPTPGRAGLLNTSGTKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLEVRGPFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVHALNTILLTSTELFQLRNQLKDLKTLESQNLFCCLYRSWCHNPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLAEVDKLVQLIECPIFTYLRLQLLDVKNNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPEL 725
[Close]
BLAST of Protein VAC14 homolog vs. UniProt/SwissProt
Match: sp|A2VE70|VAC14_BOVIN (Protein VAC14 homolog OS=Bos taurus OX=9913 GN=VAC14 PE=2 SV=1)

HSP 1 Score: 394.43 bits (1012), Expect = 2.970e-123
Identity = 248/728 (34.07%), Postives = 397/728 (54.53%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSG-KYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDV-------PL--------YSEI-----NNSDFLTVPDQIKNVLEL-----TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+   +  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    + +L  FL +   S   + +  + NILV  I+  +  ++I  TA+ W+  FI+     MLP++S IL A+LP    D +  +I+  A   +  L++LV   D           +   P P       E  +    + + D   S   + V    + + +P   +   + + L+  C  S       T++A L+WL+ L      +    +++LFP L++ + D S  VI   L ++A+ +           PL        +SE+       +  L  P      LE      T N YF KF  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L     +VH LN ILL++  L   R  +K + + ES N+FC LYR+W +  V  +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D + +  L + LYGLLML+PQS AF++L +RL C+P  ++
Sbjct:    6 DFAPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNTVQIKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFIPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLKETKKSPSSVKFAEMANILV--IHCQTTDDLIQLTAMCWLREFIQLAGRVMLPYSSGILTAVLPCLAYDDRKRNIKEVASVCNQSLMKLVTPEDDEPDEPRPVVQKQAGPSPEDCAAKQEGAASGGPDGSCDSSFSSGIS-VFTPASAERAPVTLHLDGIVQVLN--CHLSDTAIGMMTRIAVLKWLYHLYIKTPRKMSRHTDSLFPVLLQTLSDESDEVILKDLEVLAEIASSPAGQTDDPGPLDGPDLRVSHSELQAPIPGRAGLLNTPG--TKGLECSPSTPTMNSYFYKFMINLLKRFSSERKLLEVRGAFIIRQLCLLLHAESIFHSMADILLREEDLTFASTMVHTLNTILLTSTELFQLRNQLKDLKTPESRNLFCCLYRSWCHKPVTTVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVKSNPYLIKALYGLLMLLPQSSAFQLLSHRLQCVPNPEL 726
[Close]
BLAST of Protein VAC14 homolog vs. TrEMBL
Match: R7UP93 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_167776 PE=4 SV=1)

HSP 1 Score: 415.616 bits (1067), Expect = 3.312e-129
Identity = 251/716 (35.06%), Postives = 396/716 (55.31%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTY--------GLALSETLHILCEFSGKYSQQTKLAALEWL-HTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLELTE--NPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDIAGL 2247
            +Y PL+++ VR+L DKLYEKRK AA++IER+VK++     + +I  I+K  G+ F    N + RKGG IGLAA AIALGK+A+ +   ++ P +    D D+RVRYY CE+LYN +KV  G+VLPYF  IFD L+K   D D++VRS    L + M+++V  S   D+ + +  LR++IY  +  AR F+++W+ +L     ++M+++LPEILDGL  +L D +  +    +  L  FL  +  S   L Y  +VNIL+   ++ S  N+I  TA+ W+  F+      MLPFTS IL AILP      +  +IR  A+     L +++  +D          D S+P          E     L E   + +        + +    +S FP +         L  +  + +L +     + QT++A+L W+ H L+        H+ E LFP L+K + DPS  V+   L ++A+ S     L      S+ + +P   +  ++LTE  N YF +F   L++   TD  +LEE+   II  LC  L    ++   + ++Q  +  +    ++  LN ILL++  L   R+ +K + +KESC++FC LY +W +N VA + LC LTQNY+H   L+  FG+ E+ V+ L EID L+Q +E+P+F FLR+ L++   +  L ++LYGLLM++PQS+AF+ L +RL C+P   +  L
Sbjct:    5 DYAPLSVSCVRSLTDKLYEKRKVAALEIERMVKEFIMHNNSTQIKKILKVLGQDFTLGQNPNARKGGLIGLAATAIALGKEANNYVPELVKPVLTCFSDSDSRVRYYGCEALYNIVKVTRGSVLPYFNDIFDGLSKLASDPDQNVRSGSELLCRLMKDIVTESCAFDLVAFIPLLRERIYTINPFARQFIVSWVVTLHDVPDIDMLVFLPEILDGLFQILGDQNAEIRKMCEVALGEFLKMIERSPQRLKYPAMVNILI--THSQSQDNVIKFTAITWLKEFVAQSGRVMLPFTSGILTAILPCLSYSDECRNIREAAKATDSSLRDIIGPLD----------DLSDP---------EEVKGEKLTEKNKNEDREKSKEDTRSLPPFLMSHFPDFLNSNRCSDVLDQTSVVRVLMQQLVHDAMQTRIASLRWIYHLLIKTPNKMFAHVGE-LFPLLLKTLSDPSDEVVLLDLEVLAEVSSNPTGLSFPPMESNLIVLPSGERVAVQLTEGMNAYFTQFMLSLLKLFSTDHLLLEERGSFIIRQLCLLLKAEDIYRCCSNVLQHEEDTRFAAHMIQSLNNILLTSTELFELRSQLKDLKTKESCSLFCCLYESWCHNSVATVGLCFLTQNYKHACDLLALFGELEVTVDFLCEIDKLVQLIESPIFTFLRLQLLEAHKNIYLVKSLYGLLMVLPQSDAFRTLQHRLQCVPSMHLTSL 698
[Close]
BLAST of Protein VAC14 homolog vs. TrEMBL
Match: A0A2R5LB63 (Putative vacuolar protein OS=Ornithodoros turicata OX=34597 PE=4 SV=1)

HSP 1 Score: 411.764 bits (1057), Expect = 5.665e-128
Identity = 248/726 (34.16%), Postives = 407/726 (56.06%), Query Frame = 1 
Query:  124 MTDEYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFS------KKDVPLYSEINNSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDIAGLIPYTAVPDPNHK 2283
            M  ++ PL+   VR L+DKLYEKRK+AA++IE++VK   ++ +T EI  ++K  G+ F  S N ++RKGG IGLAA++IALGK A  +   ++ P +  L DP++RVRYYACE+LYN +KV  G+VLP F  IFD L+K   D D++V++    LD+ ++++V  S   D+A+ +  LR++IY  +  AR F+++W++ ++    ++M+++LPEILDGL  +L D    L    +  L+ FL  ++ +   + +  ++ IL+   ++P    ++ +TA+ W+  F+     K+LP  S IL+A+LP    D   ++IR  A+ V+  L++LV   D ++                 + +V E+P    E+   +   + D +Q   +++++L       +   + LH+        S QT++A L W   L      +     E +FP L++ + DPS  V+   L ++A+ S      K+  P    +N  D  T             N YF KF + L+    +D ++LE++   II  LC  L    ++ T A I+   + L     +V  LN ILL++  L   R  +K + ++ESC++FC LYR+W +N VA +SLCLLTQNY+H   L+  F D E+ V+ L EID L+Q +E+P+F +LR+ L+D  +++ L ++LYGLLML+PQSEAF  L  RL C+P   ++ L     +P  + K
Sbjct:    2 MEKDFAPLSAACVRALNDKLYEKRKTAAMEIEKMVKDCIAKNRTAEIQKLLKLLGQDFTLSHNPNSRKGGLIGLAAMSIALGKDASLYVDDLVKPVLACLSDPESRVRYYACEALYNVVKVARGSVLPNFNDIFDCLSKLAADPDQNVKNGCELLDRLLKDIVTESSSFDLAAFMLLLRERIYASNRFARTFIVSWVSVMNSVPDIDMLVFLPEILDGLFKILEDPSVELKKMCETTLSEFLRNIIKAPQKVDFAAMIVILINHSHSP--EEMVQYTAITWMKEFVNLAGCKLLPHASGILEAVLPALAYDDSRKNIRETAKAVNHSLMQLVTLEDDNN-----------------VAEVKEHPG-KREDGVTEGHPAADVSQAADVLDRELDLTLLVNVLSRQLLHV--------SMQTRIAVLRWFFHLYIKIPNKIFRQVEEIFPVLLQTLSDPSDEVVLLDLEVLAEISSSTAGCKQPAP-EGGVNAGDSSTS----------GMNSYFTKFMFSLLDIFSSDSQLLEDRGSFIIRQLCMLLSAEDIYRTMANILLTKEDLCFASHMVQTLNTILLTSTELFELRNHLKDLKTEESCSLFCCLYRSWCHNPVATISLCLLTQNYQHACHLLHLFSDLEVTVDFLTEIDKLVQLIESPIFTYLRLQLLDTPHNSHLVKSLYGLLMLLPQSEAFHTLRTRLACVPNVQLSPLQEQKILPSDDAK 688
[Close]
BLAST of Protein VAC14 homolog vs. TrEMBL
Match: A0A3P8YD53 (Vac14 homolog (S. cerevisiae) OS=Esox lucius OX=8010 PE=4 SV=1)

HSP 1 Score: 409.453 bits (1051), Expect = 9.572e-127
Identity = 252/727 (34.66%), Postives = 402/727 (55.30%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPG-----RLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLEL--------------------TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  + +I  +I+     F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ + V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L DS + +    + +L  FL ++  +   + Y  + NILV   N     ++I  TA+ W+  FI+     +LP++S IL A+LP    D + +  +  A   +  L++LV   D  D    E    S+ PC        LL +      SL ++T   ++++D + + Q++++ L    T                      T++A L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +       S    +D     D   N LEL                    + N YF KF  +L++    + ++LE +   II  LC  L    +F++ A+I+ K + L+    +V  LN ILL++  L   R  +K + ++ESC +FC LYR+W +N VA +SLC LTQNY+H   LI+ FGD E+ V+ L E+D L+Q +E+P+F +LR+ L+D   +  L + LYGLLML+PQS+AF++L +RL C+P  ++
Sbjct:    6 DFSPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNSTQIRHVIQILASEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDSDSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVAFVPLLRERIYSNNQYARQFIISWILVLESVPDINLIDYLPEILDGLFQILGDSSKEIRRTCEVVLGEFLKEIKKTPSSVKYAEMANILVIHSN-----DLIQLTAMTWMREFIQLAGRVVLPYSSGILTAVLPCLSYDDRKKSTKEAASACNHSLMKLVTPEDDEDE---EVAGDSDSPCKSLGISWLLLSLT---VFSLLDSTDRSQVTLDLDGIVQVLDRHLHDSTT-------------------GMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPMLLKTLSDESDEVILKDLEVLAEIAS------SPAGQTDASDSCDNSDNKLELQVPVAANASSKVGDSSPSTPSMNSYFYKFMINLLKRFSLERKLLENRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMVQTLNTILLTSAELFQLRNQLKDLRTQESCALFCCLYRSWCHNPVATVSLCFLTQNYQHAYDLIQKFGDLEVTVDFLMEVDKLVQLIESPIFTYLRLQLLDVENNPYLIKALYGLLMLLPQSQAFQLLSHRLRCVPNPEL 696
[Close]
BLAST of Protein VAC14 homolog vs. TrEMBL
Match: A0A1S3H7G1 (protein VAC14 homolog isoform X3 OS=Lingula unguis OX=7574 GN=LOC106152413 PE=4 SV=1)

HSP 1 Score: 407.142 bits (1045), Expect = 5.965e-126
Identity = 241/700 (34.43%), Postives = 398/700 (56.86%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCG-ETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEIN-NSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            ++ PLT   VR L+DKLYEKRK AA++IER V++Y +    EEI  +++  G + F TS N + RKGG IG+AA AIALGK++  +   ++ P++    D D RVRYYACE+LYN +KV  G+VLP F  IFD L+K   D D++V++    LD+ ++++V  S   D+ S +  LRD+IY  +  AR FL++WI++LD    +EM+++LPEILDGL  +L D ++ +    +A L  FL  +        +  + N+LV  +++ S   +I HTAL+W+  F++     +LP+ S I+ A+LP    D   ++    A+ V+  ++ L+     +   ++E+   S     G   +V E      E  +   +++    +V+ + +  L       L +   + +L ++    +  T+ A+L W++ L+     +     +  FP L+K + DPS  V+   L ++ + S    P  + I  N + + +P Q K       + YF+KF   L+   + D ++LE++   II  LC  L    ++ +F+EI+   + L+    +V  LN ILL++  L   R ++K + ++ESC++FC LY  W ++ VA +SLC LTQNYEH   ++  FGD E+ V  L EID L+Q +E+P+F +LR+ L+DP+ + +L  +LY LLML+PQ +AF+ L +RL C+P
Sbjct:    5 DFAPLTAACVRALNDKLYEKRKGAALEIERQVREYVATNNREEITRVLQVLGGKDFSTSQNPNGRKGGLIGMAATAIALGKESSLYVREMVKPTLACFYDQDGRVRYYACEALYNIVKVARGSVLPLFNDIFDGLSKLAADPDQNVKNGSELLDRLVKDIVTESSSFDLVSFMPLLRDRIYVRNAFARQFLVSWISTLDAVPDIEMIVFLPEILDGLFNILGDENDEIRKMCEACLGEFLQGIHKERSKADFAAMANVLV--MHSQSKDPLIQHTALLWLKDFLQLSGRVILPYASGIITAVLPCLAYDASRKNTLEVAKIVNSNMISLIAAEADAGAQSAEQKVHST----GGKDEVKEGTKS--ETESAATKVATRTGKVQGVSDDLL-------LDVGAVVRVLMKYLSHEAIATREASLRWIYHLLQKTPEKMFCFVDDFFPLLMKTLSDPSDEVVLLDLEVLTEVSSN--PAGNNITLNYEEMGLPSQAKVTKPTGLSAYFVKFMVILLDSFNKDKQLLEDRGSFIIRQLCLMLNAEAIYRSFSEILLHENDLRFACHMVQTLNIILLTSTELFDLRNLLKDLKNEESCSLFCCLYHTWCHSPVATVSLCFLTQNYEHASNVLLLFGDVEVTVEFLAEIDKLVQLIESPIFTYLRLQLLDPQLNQSLITSLYALLMLLPQGDAFRTLRHRLECVP 687
[Close]
BLAST of Protein VAC14 homolog vs. TrEMBL
Match: A0A5G3HCG8 (Uncharacterized protein OS=Xenopus tropicalis OX=8364 GN=vac14 PE=4 SV=1)

HSP 1 Score: 407.142 bits (1045), Expect = 6.083e-126
Identity = 255/721 (35.37%), Postives = 405/721 (56.17%), Query Frame = 1 
Query:  142 PLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEEN-TGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCE--FSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINN-SDFLT--------VPD---QIKNVLEL-----------TENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIP 2226
            PLT NIVR L+DK+YEKRK AA++IE+LV+++ SQ  T +I  +I+   + F  S + H+RKGG IGLAA +IALGK + ++   +I P +    D D+R+RYYACE+LYN +KV  G+VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+   V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L D+ + +    +  L  FL ++      + +  + NILV  I+  S  ++I  TA+ W+  F++     MLP++S IL A+LP    D + ++I+  A   +  L++L+   D       ++TD           DV ++P+   +E+ + +HE     N  +Q  N   SP     L L   +H+L            T++  L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +        ++ + +D  T        VP+   Q  N  EL           T N YF +F  +L++   ++ ++LE +   II  LC  L    +F++ A+I+ + + L+    +V  LN ILL++  L   R+ +K + + ESCN+FC LYR+W +N VA +SLC LTQNY+H   LI+ FGD E+ V+ L E+D L+Q +E P+F +LR+ L+D      L   LYGLLML+PQS AF++L +RL C+P
Sbjct:    9 PLTPNIVRALNDKMYEKRKVAALEIEKLVREFVSQNNTAQIKHVIQILSQEFALSQHPHSRKGGLIGLAACSIALGKDSGQYLRELIEPVLTCFNDADSRLRYYACEALYNIVKVARGSVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVGFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDNSKEIRKMCEVSLGEFLKEIKKLPDSVKFAEMANILV--IHCQSTDDLIQLTAMTWMREFLQLAGRVMLPYSSGILTAVLPCLSYDDRKKNIKEVANVCNQSLMKLITPED-------DETD-----------DVRQSPATQPDEDLSSNHE-----NSSQQTSNN--SPV---SLNLDGIVHVLDRHLHESTTGMMTRICVLKWLYHLYIKTPRKMFRHTDSLFPILLKTLSDESDEVILKDLEVLAEIASSPAGQTDKMTDCTDLPTGVSELHVPVPNKVAQAHNSGELIRGLECSPSTPTMNSYFHRFMINLLKRFSSERKLLETRGAFIIRQLCLLLNAENIFHSMADILLREEDLKFASTMVQNLNSILLTSSELFQLRSQLKDLQTPESCNLFCCLYRSWCHNPVATVSLCFLTQNYQHAYHLIQKFGDLEVTVDFLTEVDKLVQLIECPIFTYLRLQLLDVENHPYLIRALYGLLMLLPQSSAFQLLSHRLQCVP 699
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Cavefish
Match: vac14 (VAC14 component of PIKFYVE complex [Source:NCBI gene;Acc:103022437])

HSP 1 Score: 401.364 bits (1030), Expect = 4.053e-127
Identity = 252/731 (34.47%), Postives = 406/731 (55.54%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCP----GRLLDVNENPSISLEENTGDH-ELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDF-----LTVPDQIKNVLELTENP-------YFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDIAGLIPYTAVPDP 2274
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  + +I  +I+     F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ + V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L DS + +    + +L  FL ++  +   + +  + NILV   N     ++I  TA+ W+  FI+     +LP++S IL A+LP    D + +  +  A   +  L++LV   D  D   S+ T  ++PP       +  D+N   S     N  D  ++++D + + Q++++                H+    +G     T++A L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +         + + D      L VPD          +P       YF KF  +L++    + ++LE +   II  LC  L    +F++ A+I+ K + L+    +V  LN ILL++  L   R  +K + + ESC +FC LYR+W +N VA +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E+P+F +LR+ L+D   +  L + LYGLLML+PQS+AF++L +RL C+P  +   L+    +P P
Sbjct:    6 DFSPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNSTQIRHVIQILASEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDSDSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVAFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDSSKEIRRMCEVVLGEFLKEIKKTPSSVKFAEMANILVIHSN-----DLIQLTAMTWMREFIQLAGRVVLPYSSGILTAVLPCLSYDDRKKITKEAASACNHSLMKLVTPEDDEDEEESQST--TSPPSKDTSTKKEGDINGKIS-----NLADRSQVTLDLDGIVQVLDR----------------HLHDSLTG---MMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPMLLKTLSDESDEVILKDLEVLAEIASSPAGQTESLGSCDGSDKTELHVPDGSAGSKVADSSPSTPSMNSYFYKFMINLLQRFSLERKLLETRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMVQTLNTILLTSAELFQLRNQLKDLRTPESCTLFCCLYRSWCHNPVATVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLIEVDKLVQLIESPIFTYLRLQLLDVENNPYLIKALYGLLMLLPQSQAFQLLSHRLRCVPNPE---LMRTVEIPKP 702
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Cavefish
Match: vac14 (VAC14 component of PIKFYVE complex [Source:NCBI gene;Acc:103022437])

HSP 1 Score: 400.593 bits (1028), Expect = 1.691e-126
Identity = 259/748 (34.63%), Postives = 419/748 (56.02%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVF--QINNPS--CSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCP----GRLLDVNENPSISLEENTGDHELS------VDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDF-----LTVPDQIK---NVLELTE------------NPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDIAGLIPYTAVPDP 2274
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  + +I  +I+     F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ + V  LR++IY ++  AR F+I+WI  L+    + ++ YLPEILDGL  +L DS + +    + +L  FL ++  +   + +  + NILV   Q+++ S   +++I  TA+ W+  FI+     +LP++S IL A+LP    D + +  +  A   +  L++LV   D  D   S+ T  ++PP       +  D+N++ + S +E+TG   +S       D +QV   ++         G+      H+    +G     T++A L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +         + + D      L VPD  K   + L ++             N YF KF  +L++    + ++LE +   II  LC  L    +F++ A+I+ K + L+    +V  LN ILL++  L   R  +K + + ESC +FC LYR+W +N VA +SLC LTQNY H   LI+ FGD E+ V+ L E+D L+Q +E+P+F +LR+ L+D   +  L + LYGLLML+PQS+AF++L +RL C+P  +   L+    +P P
Sbjct:    6 DFSPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNSTQIRHVIQILASEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDSDSRLRYYACEALYNIVKVARGAVLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVAFVPLLRERIYSNNQYARQFIISWILVLESVPDINLLDYLPEILDGLFQILGDSSKEIRRMCEVVLGEFLKEIKKTPSSVKFAEMANILVIHCQVSDESKLTNDLIQLTAMTWMREFIQLAGRVVLPYSSGILTAVLPCLSYDDRKKITKEAASACNHSLMKLVTPEDDEDEEESQST--TSPPSKDTSTKKEGDINDSLNAS-QESTGLSNISFFNPTGADRSQVTLDLD---------GIVQVLDRHLHDSLTG---MMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPMLLKTLSDESDEVILKDLEVLAEIASSPAGQTESLGSCDGSDKTELHVPDGSKVGQHQLGMSSKVADSSPSTPSMNSYFYKFMINLLQRFSLERKLLETRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMVQTLNTILLTSAELFQLRNQLKDLRTPESCTLFCCLYRSWCHNPVATVSLCFLTQNYRHAYDLIQKFGDLEVTVDFLIEVDKLVQLIESPIFTYLRLQLLDVENNPYLIKALYGLLMLLPQSQAFQLLSHRLRCVPNPE---LMRTVEIPKP 735
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004408.1 (pep scaffold:Pmarinus_7.0:GL483904:3560:7746:1 gene:ENSPMAG00000004022.1 transcript:ENSPMAT00000004408.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.4774 bits (171), Expect = 9.564e-15
Identity = 35/85 (41.18%), Postives = 53/85 (62.35%), Query Frame = 1 
Query: 2005 LIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSD--IAGLIP 2253
            +++     E+ V+ L E+D L+Q +E+P+F +LR+ L+D      L + LYGLLML+PQS AF +L  RL C+P     +A L P
Sbjct:    1 IVRPSAGLEVTVDFLTEVDKLVQLIESPIFTYLRLQLLDVESLPYLIKALYGLLMLLPQSSAFTLLRQRLACVPDPQLMVADLSP 85
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Yeast
Match: VAC14 (Enzyme regulator; involved in synthesis of phosphatidylinositol 3,5-bisphosphate, in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; binds negative (Fig4p) and positive (Fab1p) regulators of PtdIns(3,5)P(2) to control endolysosome function; similar to mammalian Vac14p [Source:SGD;Acc:S000004378])

HSP 1 Score: 133.65 bits (335), Expect = 1.747e-32
Identity = 86/256 (33.59%), Postives = 123/256 (48.05%), Query Frame = 1 
Query:  154 NIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKH-CGETFCTSSNCHNRKGGTIGLAAVAIALG-KQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVM-----------NSDH---------------------------LDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDS 801
            +I + L DKLYEKRK+AA+++E+LVKQ   +G  + I  II   C +          R  G +GLAA AIALG      +   I+ P +    D + +VR+YACESLYN  K+  G +L YF  IFD L K   DT+  VR A   LD+ ++++V            N  H                             +   +  L ++IY  +   R+FL++W+  L  T G+E++ YLP  L GL   L DS
Sbjct:    4 SIAKGLSDKLYEKRKAAALELEKLVKQCVLEGDYDRIDKIIDELCRDYAYALHQPMARNAGLMGLAATAIALGINDVGRYLRNILPPVLACFGDQNDQVRFYACESLYNIAKIAKGEILVYFNEIFDVLCKISADTENSVRGAAELLDRLIKDIVAERASNYISIVNNGSHGLLPAIKTDPISGDVYQEEYEQDNQLAFSLPKFIPLLTERIYAINPDTRVFLVDWLKVLLNTPGLELISYLPSFLGGLFTFLGDS 259

HSP 2 Score: 115.161 bits (287), Expect = 1.292e-26
Identity = 73/281 (25.98%), Postives = 146/281 (51.96%), Query Frame = 1 
Query: 1381 TKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCI 2223
             K+A L+WL  +      Q L  ++++F +L+K + +  S +I   L L+         L S+ N++                   Y  +F  DL+     D ++++ + + I+  +  +L P  V+   + I+   +       ++  L+  L+++P ++S R  +++    E    F  L+++W  N V+++SLC + +NYE    +++T+ + E+ +N L ++D+LIQ  E+PVF  +R+ L++ +    L + L+G+LM+IPQS+AF+ L  RLN +
Sbjct:  496 AKIACLDWLILIYHKAPNQILKHNDSMFLTLLKSLSNRDSVLIEKALSLLQS-------LCSDSNDN-------------------YLRQFLQDLLTLFKRDTKLVKTRANFIMRQISSRLSPERVYKVISSILDNYNDTTFVKMMIQILSTNLITSPEMSSLRNKLRTC---EDGMFFNSLFKSWCPNPVSVISLCFVAENYELAYTVLQTYANYELKLNDLVQLDILIQLFESPVFTRMRLQLLEQQKHPFLHKCLFGILMIIPQSKAFETLNRRLNSL 747
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Nematostella
Match: EDO30641 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T069])

HSP 1 Score: 365.155 bits (936), Expect = 3.138e-114
Identity = 252/718 (35.10%), Postives = 403/718 (56.13%), Query Frame = 1 
Query:  124 MTD-EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDV------------PLYSEINNSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            MT+ +Y PLT N+VR L+DKLYEKRK+AA+++ER+VK++ +  + ++I  + +   E F  S N H RKGG IGLAA AIALGK A  +   +I P +    D D+RVRYYACE+LYN  KV  G+VLP+F  +F+ L+K   D D +V++    LD+ ++++V  S   D+ S +  LR++IY  +  A+ FL++W+  LD    ++++ +LPE LDGL ++  D    +    +ALL  FL +++ S   + +  ++NILV  +++ S   +I  TAL W+  FI      MLPF + ++KA+LP    D+  ++I+  A+ V+  ++ L+          +E  D+             E  +IS+E    D++++V   QV               L L   + +L +     S QT++A L W+  L      +     E LFP L+K + DPS  V+   L ++A+ S                P +S    SD  + P Q+        N YF KF + L+    T+ ++LEE+   I+  LC  L    ++ + +EI+ + + LQ    +V  LN ILL++  L   R  +K + + ESC++FC LY++W++N VA +SLCLLTQNY+H   L+  FGD E++V+ L +ID L+Q +E+P+F +LR+ L+D   +  L ++LYGLLML+PQS+AF  L +RL+C+P   +
Sbjct:    1 MTEKDYLPLTQNVVRGLNDKLYEKRKTAALEVERMVKEFVANNEVKQIKKLTQVLAEDFAVSHNSHARKGGLIGLAAAAIALGKDAGLYLKDLIPPVLSCFYDQDSRVRYYACEALYNIAKVARGSVLPFFNEVFEGLSKLAADPDPNVKNGAELLDRLVKDIVTESSSFDIISFMPLLRERIYTANPYAKQFLVSWLRVLDSVPELDLINHLPEFLDGLFVIFKDRSAEIRKMCEALLGEFLREIIKSPQTVNFAEMINILV--LHSQSEDEVIQFTALSWLKEFITLSGRTMLPFCAAVIKAVLPCVSYDQDKQNIKEVAKAVNQSMMRLI----------TEDDDK-------------EADAISME---CDNDITV--VQVH--------------LDLGPVVEVLTKQLTHKSIQTRIAMLRWVLLLHMKTPNKLFLQIEKLFPELLKTLSDPSDEVVLLDLEVLAEISASAAGPPRNTPPSPLTPAWSA-GLSD-ASPPRQL--------NKYFHKFMHSLMLLFRTERKLLEERGSFILRQLCLLLNVEDIYRSLSEILIQEEDLQFAALMVRYLNMILLTSGELFDLRMQLKDLQTAESCSLFCCLYQSWAHNAVATVSLCLLTQNYKHACDLLMIFGDLEVNVDFLVQIDKLVQLIESPIFTYLRLQLLDTGRNYYLLKSLYGLLMLLPQSDAFTTLRHRLDCVPNGRV 664
[Close]
BLAST of Protein VAC14 homolog vs. Ensembl Medaka
Match: vac14 (VAC14 component of PIKFYVE complex [Source:NCBI gene;Acc:101161405])

HSP 1 Score: 390.963 bits (1003), Expect = 8.490e-123
Identity = 248/733 (33.83%), Postives = 404/733 (55.12%), Query Frame = 1 
Query:  133 EYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVF--QINNPS--CSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPC----PGRLLDVNENPSISLEENTGDHELS-VDPNQVKQIINQKLSPFPTYGLALSETLHILCE--FSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSD------FLTVPDQIKNVLELTENP--------------YFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDI 2238
            ++ PLT NIVR L+DKLYEKRK AA++IE+LV+++ +Q  + +I  +I+     F  S + H+RKGG IGLAA +IALGK +  +   +I P +    D D+R+RYYACE+LYN +KV  G VLP+F  +FD L+K   D D +V+S    LD+ ++++V  S+  D+ + V  LR++IY ++  AR F+I+WI  ++    + ++ YLPEILDGL  +L D+ + +    + +L  FL ++  +   + +  + NILV   Q+ + +   +++I  TA+ W+  FI+     +LP++S IL A+LP    D + ++ +  A   +  L++LV   D  D          +P      P    D N+  + S +E+TG   +S   P   ++         P   L L   + +L            T++A L+WL+ L      +    +++LFP L+K + D S  VI   L ++A+ +        +  + D       L VP   K   + + NP              YF KF  +L++    + ++LE +   II  LC  L    +F++ A+I+ K + L+    +V  LN ILL++  L   R  +K + ++ESC +FC LYR+W +N VA +SLC LTQNY H   LI+ FG+ E+ V+ L E+D L+Q +E+P+F +LR+ L+D   +  L + LYGLLML+PQS+AF++L +RL C+P  ++
Sbjct:    6 DFTPLTPNIVRALNDKLYEKRKVAALEIEKLVREFVAQNNSTQIRHVIQILASEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDSDSRLRYYACEALYNIVKVARGAVLPHFNLLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNTFDLVAFVPLLRERIYSNNQYARQFIISWIHVMESVPDINLLDYLPEILDGLFQILGDNSKEIRRTCEVVLGEFLKEIKKTPSKVKFAEMANILVIHCQVADEAKVTNDLIQLTAMTWMREFIQLAGRVVLPYSSGILTAVLPCLSYDDRKKNTKEAASACNNSLMKLVTPEDDDDDEEEGSKSLGSPSTGDEQPKVEADSNDMLNAS-QESTGFSNISFFTPASTER---------PQVNLDLDGIVQVLNRHLHDSSTGMMTRIAVLKWLYHLYIKTPRKMFRHTDSLFPILLKTLSDESDEVILKDLEVLAEIASSPAGQTDQAFSCDSTVNNLVLKVPQGPKPGQQPSTNPKAVDSSPSTPSMNSYFYKFMINLLKRFSLERKLLEVRGAFIIRQLCLLLHAENIFHSMADILLKEEDLKFASTMVQTLNTILLTSAELFELRNQLKDLHTQESCTLFCCLYRSWCHNPVATVSLCFLTQNYRHAYDLIQKFGNLEVTVDFLMEVDKLVQLIESPIFTYLRLELLDVENNPYLIKALYGLLMLLPQSQAFQLLSHRLRCVPNPEL 728
[Close]
BLAST of Protein VAC14 homolog vs. Planmine SMEST
Match: SMESG000048581.1 (SMESG000048581.1)

HSP 1 Score: 1505.35 bits (3896), Expect = 0.000e+0
Identity = 772/773 (99.87%), Postives = 772/773 (99.87%), Query Frame = 1 
Query:  124 MTDEYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETXXXXXXXXXXXXXXXXXSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDIAGLIPYTAVPDPNHKXXXXXXXXXXXXXXXXXXQHRLHSQMLKRQHQQQSIHYVSSSKTSFIDGHLSL 2442
            MTDEYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETLVNKLKALLNNFLNQLLSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDIAGLIPYTAVPDPNHKLISENINFNNLLENLKNIQHRLHSQMLKRQHQQQSIHYVSSSKTSFID HLSL
Sbjct:    1 MTDEYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALIIKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLLKDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRSAIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSLDRTNGVEMVLYLPEILDGLLLMLNDSDETLVNKLKALLNNFLNQLLSSDVDLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLILKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSNPPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGLALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSLIKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLELTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFAEIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCRLYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQFLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCIPKSDIAGLIPYTAVPDPNHKLISENINFNNLLENLKNIQHRLHSQMLKRQHQQQSIHYVSSSKTSFIDSHLSL 773
The following BLAST results are available for this feature:
BLAST of Protein VAC14 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
VAC141.006e-12434.02VAC14 component of PIKFYVE complex [Source:HGNC Sy... [more]
VAC142.934e-4047.13VAC14 component of PIKFYVE complex [Source:HGNC Sy... [more]
VAC141.258e-3844.59VAC14 component of PIKFYVE complex [Source:HGNC Sy... [more]
VAC146.457e-3033.82VAC14 component of PIKFYVE complex [Source:HGNC Sy... [more]
VAC148.101e-656.10VAC14 component of PIKFYVE complex [Source:HGNC Sy... [more]
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BLAST of Protein VAC14 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
vacl-141.907e-4433.23VAC (Yeast VACuole morphology)-Like [Source:UniPr... [more]
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BLAST of Protein VAC14 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG56081.844e-9129.94gene:FBgn0038058 transcript:FBtr0082680[more]
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BLAST of Protein VAC14 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
vac145.021e-12634.80vac14 homolog (S. cerevisiae) [Source:NCBI gene;Ac... [more]
vac143.621e-12534.15vac14 homolog (S. cerevisiae) [Source:NCBI gene;Ac... [more]
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BLAST of Protein VAC14 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
vac143.874e-12935.37Vac14 homolog [Source:NCBI gene;Acc:100216224][more]
vac146.028e-12934.52Vac14 homolog [Source:NCBI gene;Acc:100216224][more]
vac149.611e-12934.72Vac14 homolog [Source:NCBI gene;Acc:100216224][more]
vac141.423e-12834.54Vac14 homolog [Source:NCBI gene;Acc:100216224][more]
vac144.261e-12834.99Vac14 homolog [Source:NCBI gene;Acc:100216224][more]
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BLAST of Protein VAC14 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Vac148.936e-12634.42Vac14 homolog (S. cerevisiae) [Source:MGI Symbol;A... [more]
Vac145.141e-7134.18Vac14 homolog (S. cerevisiae) [Source:MGI Symbol;A... [more]
Vac143.940e-3750.00Vac14 homolog (S. cerevisiae) [Source:MGI Symbol;A... [more]
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BLAST of Protein VAC14 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q68F38|VAC14_XENLA2.370e-12535.12Protein VAC14 homolog OS=Xenopus laevis OX=8355 GN... [more]
sp|Q66L58|VAC14_DANRE3.790e-12534.80Protein VAC14 homolog OS=Danio rerio OX=7955 GN=va... [more]
sp|Q80WQ2|VAC14_MOUSE6.251e-12534.42Protein VAC14 homolog OS=Mus musculus OX=10090 GN=... [more]
sp|Q08AM6|VAC14_HUMAN4.829e-12434.02Protein VAC14 homolog OS=Homo sapiens OX=9606 GN=V... [more]
sp|A2VE70|VAC14_BOVIN2.970e-12334.07Protein VAC14 homolog OS=Bos taurus OX=9913 GN=VAC... [more]
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BLAST of Protein VAC14 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
R7UP933.312e-12935.06Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A2R5LB635.665e-12834.16Putative vacuolar protein OS=Ornithodoros turicata... [more]
A0A3P8YD539.572e-12734.66Vac14 homolog (S. cerevisiae) OS=Esox lucius OX=80... [more]
A0A1S3H7G15.965e-12634.43protein VAC14 homolog isoform X3 OS=Lingula unguis... [more]
A0A5G3HCG86.083e-12635.37Uncharacterized protein OS=Xenopus tropicalis OX=8... [more]
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BLAST of Protein VAC14 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
vac144.053e-12734.47VAC14 component of PIKFYVE complex [Source:NCBI ge... [more]
vac141.691e-12634.63VAC14 component of PIKFYVE complex [Source:NCBI ge... [more]
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BLAST of Protein VAC14 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000004408.19.564e-1541.18pep scaffold:Pmarinus_7.0:GL483904:3560:7746:1 gen... [more]
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BLAST of Protein VAC14 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
VAC141.747e-3233.59Enzyme regulator; involved in synthesis of phospha... [more]
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BLAST of Protein VAC14 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO306413.138e-11435.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Protein VAC14 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
vac148.490e-12333.83VAC14 component of PIKFYVE complex [Source:NCBI ge... [more]
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BLAST of Protein VAC14 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000048581.10.000e+099.87SMESG000048581.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014485 ID=SMED30014485|Name=Protein VAC14 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=2672bp
TAATTAACTTTTTTAAATTGACTGAAATTTTGTAATTTTAATATACTTTT
ATTTTAAAATACTTTATTCCGTTTGGAAGTAATATTTGCAAATTGCAAGT
TCTTATACTAAAAATATTTACCAATGACTGATGAATATTATCCTTTGACT
CTGAATATTGTCAGGAACTTACATGATAAACTTTACGAAAAACGTAAATC
AGCGGCCATTGACATTGAAAGATTAGTAAAGCAATATCAGAGTCAAGGAA
AGACAGAAGAAATCGCTTTGATAATCAAACACTGTGGTGAAACGTTTTGT
ACCTCCAGCAATTGTCACAACCGGAAAGGTGGAACAATCGGACTTGCAGC
AGTGGCAATTGCATTGGGAAAACAAGCAGATGAATTTTGTAGTCTTATAA
TTTGTCCATCAATCAAATTGCTTAAAGATCCAGACGCAAGAGTTCGATAT
TATGCCTGTGAAAGCTTATATAATTGCATTAAAGTACTGGGAGGAAATGT
TTTACCTTATTTCCAGTCGATTTTTGATGCTTTAGCTAAAGGCTATGAGG
ACACTGATAAAGATGTCAGGTCTGCAATTATTCAGTTGGATAAGTCAATG
CGAGAAATGGTGATGAACTCCGATCATCTCGATGTTGCCAGCATTGTCAC
GTATTTGAGGGATAAAATATACCCAGATTCAACACAAGCTCGCCTATTTC
TGATTAATTGGATAACTTCTCTCGACAGGACAAACGGAGTTGAAATGGTT
CTTTATCTTCCTGAAATTTTGGATGGCCTCTTGTTAATGCTAAATGATTC
CGATGAAACTCTCGTTAACAAACTTAAAGCTTTATTGAACAATTTTTTAA
ACCAACTACTATCAAGCGATGTTGATTTGGTATATCGAAGATTAGTAAAC
ATTCTTGTTTTCCAAATAAACAATCCCAGTTGTAGCAATATTATCAATCA
CACTGCATTAGTCTGGATAGCAAGGTTTATTGAGTCATTCAAGTATAAAA
TGCTTCCATTTACATCGTTAATTTTGAAAGCTATTTTACCATTTTTTGAT
GTAGATAGAAAAGATGAACATATTCGAAATCAAGCAAGAAATGTCAGTCT
TTTGTTACTGGAGCTTGTTCGAACTATGGATCATTCGGATAGAACGACAT
CAGAAAAAACAGATCAATCAAATCCTCCATGTCCAGGTAGATTGTTGGAT
GTTAATGAAAATCCATCTATTTCCTTAGAAGAAAATACTGGAGACCACGA
ATTATCAGTCGACCCAAATCAAGTAAAACAGATAATAAATCAAAAATTGT
CTCCATTTCCAACGTATGGATTAGCCTTATCGGAAACTTTACACATTCTA
TGTGAATTTTCCGGTAAATATAGCCAACAAACCAAGCTGGCTGCATTGGA
ATGGTTACACACATTGATGGATGCAGATCTCTGTCAAACCCTTCACCTTT
CTGAAACTCTCTTTCCCTCATTAATCAAATTCGTTGTTGACCCATCATCA
GGGGTAATTCGAGCCGGATTGTTGTTAGTTGCCAAATTCTCCAAGAAGGA
TGTTCCCTTATATTCAGAAATCAACAACAGCGATTTTCTTACGGTTCCAG
ATCAAATAAAAAACGTTTTAGAGCTTACCGAAAATCCGTACTTTTTAAAA
TTTGCCTACGACCTTATTCGCCATCTTGATACCGACGTTGAAATGTTGGA
AGAGAAATGCGACCTAATAATTGGTGATCTCTGCTATCAACTCGGTCCCT
GTCTTGTGTTCAATACCTTCGCAGAGATAATACAAAAATTAGACTCATTA
CAAGAGAAGTTTCGGCTCGTTCACAAATTAAATCGAATATTGTTATCTAA
TCCTAATTTGACTAGTTTCAGGGCCATGATAAAATCTATTGATTCTAAAG
AATCATGTAACATTTTTTGTCGACTTTATCGAGCATGGTCCTATAATCGA
GTTGCTCTTCTAAGTCTATGCTTACTGACTCAAAATTACGAGCACTGTAG
AAGACTTATTAAAACATTTGGAGATCAAGAAATGGATGTAAATACGTTGA
ATGAAATAGATTTATTAATACAGTTTCTTGAAGCCCCAGTATTTGCATTT
CTTCGAATGCATTTAATGGATCCACGTTATTCTGCCGCGCTTAGTGAAAC
GCTTTACGGTCTTCTTATGCTAATTCCACAATCAGAAGCCTTTAAAATTT
TACTGAATCGACTTAATTGCATCCCAAAAAGCGATATAGCTGGATTAATT
CCATATACAGCTGTTCCCGATCCCAATCATAAGTTGATCAGTGAAAATAT
CAATTTTAACAACTTATTGGAAAATTTGAAAAACATTCAACACCGTCTGC
ATAGTCAGATGCTGAAGCGACAGCACCAACAGCAGAGCATTCATTATGTT
TCATCTTCTAAAACATCATTTATAGACGGCCATTTGAGTTTGTGATAAAT
GAGGTGAAGTGCATTATTGATTATGATTATTGCAAGTGGATTGAAGAGTT
AATTTTGTTTTTCTGAGTATTGAATTGAGATTTCTGCCAAAGTTTTAGTT
AATTCGACTTTATATTGAATTATCTAGAGTAGTGTGTCTCAAATGAGAGT
CGATTGGCCACAAGGGCAATGTTACAATCAAAATTTGAAAAATTTTAATT
TAATAACTAAATTACGACAAAT
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protein sequence of SMED30014485-orf-1

>SMED30014485-orf-1 ID=SMED30014485-orf-1|Name=SMED30014485-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=774bp
MTDEYYPLTLNIVRNLHDKLYEKRKSAAIDIERLVKQYQSQGKTEEIALI
IKHCGETFCTSSNCHNRKGGTIGLAAVAIALGKQADEFCSLIICPSIKLL
KDPDARVRYYACESLYNCIKVLGGNVLPYFQSIFDALAKGYEDTDKDVRS
AIIQLDKSMREMVMNSDHLDVASIVTYLRDKIYPDSTQARLFLINWITSL
DRTNGVEMVLYLPEILDGLLLMLNDSDETLVNKLKALLNNFLNQLLSSDV
DLVYRRLVNILVFQINNPSCSNIINHTALVWIARFIESFKYKMLPFTSLI
LKAILPFFDVDRKDEHIRNQARNVSLLLLELVRTMDHSDRTTSEKTDQSN
PPCPGRLLDVNENPSISLEENTGDHELSVDPNQVKQIINQKLSPFPTYGL
ALSETLHILCEFSGKYSQQTKLAALEWLHTLMDADLCQTLHLSETLFPSL
IKFVVDPSSGVIRAGLLLVAKFSKKDVPLYSEINNSDFLTVPDQIKNVLE
LTENPYFLKFAYDLIRHLDTDVEMLEEKCDLIIGDLCYQLGPCLVFNTFA
EIIQKLDSLQEKFRLVHKLNRILLSNPNLTSFRAMIKSIDSKESCNIFCR
LYRAWSYNRVALLSLCLLTQNYEHCRRLIKTFGDQEMDVNTLNEIDLLIQ
FLEAPVFAFLRMHLMDPRYSAALSETLYGLLMLIPQSEAFKILLNRLNCI
PKSDIAGLIPYTAVPDPNHKLISENINFNNLLENLKNIQHRLHSQMLKRQ
HQQQSIHYVSSSKTSFIDGHLSL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006661phosphatidylinositol biosynthetic process
GO:0043550regulation of lipid kinase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR026825Vac14
IPR021841VAC14_Fig4p-bd
IPR011989ARM-like
IPR032878Vac14_Fab1-bd
IPR016024ARM-type_fold
Vocabulary: molecular function
TermDefinition
GO:0005488binding
Vocabulary: cellular component
TermDefinition
GO:0005768endosome
GO:0010008endosome membrane
GO:0016020membrane
GO:0070772PAS complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR021841Vacuolar protein 14 C-terminal Fig4-binding domainPFAMPF11916Vac14_Fig4_bdcoord: 523..700
e-value: 9.1E-56
score: 188.3
IPR011989Armadillo-like helicalGENE3DG3DSA:1.25.10.10coord: 22..245
e-value: 3.7E-11
score: 45.0
IPR032878Vacuole morphology and inheritance protein 14, Fab1-binding regionPFAMPF12755Vac14_Fab1_bdcoord: 66..160
e-value: 1.6E-30
score: 105.6
IPR026825Vacuole morphology and inheritance protein 14PANTHERPTHR16023TAX1 BINDING PROTEIN-RELATEDcoord: 1..755
IPR016024Armadillo-type foldSUPERFAMILYSSF48371ARM repeatcoord: 12..685