Ring finger protein 145b

Overview
NameRing finger protein 145b
Smed IDSMED30014425
Length (bp)946
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ring finger protein 145b (SMED30014425) t-SNE clustered cells

Violin plots show distribution of expression levels for Ring finger protein 145b (SMED30014425) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014425

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30014425h1SMcG0004150 SmedASXL_010273SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
zeta neoblastSMED30014425h1SMcG0004150 dd_Smed_v4_24476_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Fly
Match: CG9014 (gene:FBgn0028847 transcript:FBtr0343664)

HSP 1 Score: 49.2914 bits (116), Expect = 1.966e-6
Identity = 22/48 (45.83%), Postives = 29/48 (60.42%), Query Frame = 1 
Query:   97 LCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFT 240
            +C IC D  +  E    S C+H FC +CI  W+I+  ICP+DRS L T
Sbjct:   17 ICPICTDVLE--EPVQSSECEHAFCRACIDKWMIQKQICPVDRSGLLT 62
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Fly
Match: CG9014 (gene:FBgn0028847 transcript:FBtr0080579)

HSP 1 Score: 49.2914 bits (116), Expect = 1.966e-6
Identity = 22/48 (45.83%), Postives = 29/48 (60.42%), Query Frame = 1 
Query:   97 LCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFT 240
            +C IC D  +  E    S C+H FC +CI  W+I+  ICP+DRS L T
Sbjct:   17 ICPICTDVLE--EPVQSSECEHAFCRACIDKWMIQKQICPVDRSGLLT 62
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Fly
Match: gol (gene:FBgn0004919 transcript:FBtr0300178)

HSP 1 Score: 48.1358 bits (113), Expect = 5.667e-6
Identity = 29/91 (31.87%), Postives = 44/91 (48.35%), Query Frame = 1 
Query:   94 DLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGDHPIQDLNVGDIISDQLSHEEQLIIA--EHLPIII 360
            D C+IC + YK  +   I PC+H+F  +CI  W+IE+  CP+ + D+                 VGD I    S +    IA  E +P+I+
Sbjct:  301 DCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLK----------FYGYVVGDQIYQTPSPQHTAPIASIEEVPVIV 381
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Fly
Match: gol (gene:FBgn0004919 transcript:FBtr0306330)

HSP 1 Score: 48.1358 bits (113), Expect = 5.667e-6
Identity = 29/91 (31.87%), Postives = 44/91 (48.35%), Query Frame = 1 
Query:   94 DLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGDHPIQDLNVGDIISDQLSHEEQLIIA--EHLPIII 360
            D C+IC + YK  +   I PC+H+F  +CI  W+IE+  CP+ + D+                 VGD I    S +    IA  E +P+I+
Sbjct:  301 DCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLK----------FYGYVVGDQIYQTPSPQHTAPIASIEEVPVIV 381
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Fly
Match: gol (gene:FBgn0004919 transcript:FBtr0300179)

HSP 1 Score: 48.1358 bits (113), Expect = 7.723e-6
Identity = 19/48 (39.58%), Postives = 30/48 (62.50%), Query Frame = 1 
Query:   94 DLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLF 237
            D C+IC + YK  +   I PC+H+F  +CI  W+IE+  CP+ + D+ 
Sbjct:  301 DCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVL 348
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Zebrafish
Match: si:dkeyp-86f7.4 (si:dkeyp-86f7.4 [Source:ZFIN;Acc:ZDB-GENE-091204-252])

HSP 1 Score: 49.6766 bits (117), Expect = 1.953e-6
Identity = 18/59 (30.51%), Postives = 33/59 (55.93%), Query Frame = 1 
Query:   91 DDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGDH 267
            D  C +C D Y+  E   + PC+H +   CI+ W++E+P CP+ + ++   S++   D 
Sbjct:  259 DTGCVVCTDSYQRGEQVTVLPCRHLYHKKCIEPWLLEHPTCPMCKYNILKSSVSLQADQ 317
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Zebrafish
Match: si:ch211-59o9.10 (si:ch211-59o9.10 [Source:ZFIN;Acc:ZDB-GENE-101206-1])

HSP 1 Score: 48.1358 bits (113), Expect = 8.646e-6
Identity = 19/45 (42.22%), Postives = 26/45 (57.78%), Query Frame = 1 
Query:  100 CSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDL 234
            C IC+  YK  E   + PC H + V CI  W+ EN  CP+ R+D+
Sbjct:  423 CQICFSEYKAGERLRMLPCLHDYHVKCIDRWLKENATCPICRADV 467
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Xenopus
Match: ENSXETT00000026890.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:6:49429561:49430820:-1 gene:ENSXETG00000013300.1 transcript:ENSXETT00000026890.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 47.7506 bits (112), Expect = 7.940e-7
Identity = 21/55 (38.18%), Postives = 31/55 (56.36%), Query Frame = 1 
Query:   88 FDDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISIT 252
             D  C IC D  + N+ +    C+HKFC  CI++WI +N  CPL R  + ++  T
Sbjct:   11 LDSRCPICLD--RFNDVSWTDACKHKFCFLCIEMWIQDNGSCPLCRQPVRSVKNT 63
[Close]
BLAST of Ring finger protein 145b vs. TrEMBL
Match: U3KK95 (RING-type domain-containing protein OS=Ficedula albicollis OX=59894 PE=4 SV=1)

HSP 1 Score: 53.5286 bits (127), Expect = 8.927e-6
Identity = 24/60 (40.00%), Postives = 33/60 (55.00%), Query Frame = 1 
Query:   85 EFDDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGD 264
            E D  C IC D  K  + A   PC+H+FC+ CI  W   NP CPL R+ + T+  +  G+
Sbjct:    4 ETDGNCPICQDSQK--DVASALPCRHRFCLGCILRWAHRNPSCPLCRTPIETVRFSEQGE 61
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Sea Lamprey
Match: rnf41l (ring finger protein 41, like [Source:ZFIN;Acc:ZDB-GENE-030131-9441])

HSP 1 Score: 45.0542 bits (105), Expect = 2.120e-6
Identity = 20/46 (43.48%), Postives = 27/46 (58.70%), Query Frame = 1 
Query:   97 LCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDL 234
            LC +C D   V E  + +PC+H FC +CI  W++ N  CP DR  L
Sbjct:   17 LCCVCRD---VLEDPLQAPCEHAFCSACIHGWLVHNHTCPEDRQPL 59
[Close]
BLAST of Ring finger protein 145b vs. Ensembl Yeast
Match: YBR062C_mRNA (Protein of unknown function that interacts with Msb2p; may play a role in activation of the filamentous growth pathway [Source:SGD;Acc:S000000266])

HSP 1 Score: 43.8986 bits (102), Expect = 7.668e-6
Identity = 20/55 (36.36%), Postives = 30/55 (54.55%), Query Frame = 1 
Query:   94 DLCSICYDCYKVNEYAII---SPCQHKFCVSCIKIWIIENPICPLDRSDLFTISI 249
            D CSICY  Y  +EY ++     C HKF + C+ +W+  +  CPL R ++    I
Sbjct:  107 DNCSICYTNYLEDEYPLVVELPHCHHKFDLECLSVWLSRSTTCPLCRDNVMGHRI 161
[Close]
BLAST of Ring finger protein 145b vs. Planmine SMEST
Match: SMESG000023870.1 (SMESG000023870.1)

HSP 1 Score: 398.282 bits (1022), Expect = 1.302e-139
Identity = 229/247 (92.71%), Postives = 230/247 (93.12%), Query Frame = 1 
Query:   85 EFDDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGDHPIQDLNVGDIISDQLSHEEQLIIAEHLPIIIDLLHNLEIYSKMFISLVESLKLYKTNFSEINFQKILFSNSTESKELFEIFSINIQNITKDYIHDFQDIAXXXXXXXXXXXXXXXXXXXXXEAYKTRLTNEIKLKEHYDLITNFIYCYECLEYLRSIFYHSSLFFNIANNRFQQHSFEKLIDKYFL 825
            EFDDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDR                 +LNVGDIISDQLSHEEQLIIAEHLPIIIDLLHNLEIYSKMFISLVESLKLYKTNFSEINFQKILFSNSTESKELFEIFSINIQNITKDYIHDFQDIALNIKNQLDLLNDKLDILDKKNEAYKTRLTNEIKLKEHYDLITNFIYCYECLEYLRSIFYHSSLFFNIANNRFQQHSFEKLIDKYFL
Sbjct:    3 EFDDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDR-----------------NLNVGDIISDQLSHEEQLIIAEHLPIIIDLLHNLEIYSKMFISLVESLKLYKTNFSEINFQKILFSNSTESKELFEIFSINIQNITKDYIHDFQDIALNIKNQLDLLNDKLDILDKKNEAYKTRLTNEIKLKEHYDLITNFIYCYECLEYLRSIFYHSSLFFNIANNRFQQHSFEKLIDKYFL 232

HSP 2 Score: 80.1073 bits (196), Expect = 7.339e-17
Identity = 40/44 (90.91%), Postives = 41/44 (93.18%), Query Frame = 3 
Query:  813 QIFP*HTWEIINNLNMEIPMLKLTNRIVNCIVLKFATISIDINK 944
            + F  HTWEIINNLNMEIPMLKLTNRIVNCIVLKFATISIDINK
Sbjct:  229 KYFLKHTWEIINNLNMEIPMLKLTNRIVNCIVLKFATISIDINK 272
[Close]
BLAST of Ring finger protein 145b vs. Planmine SMEST
Match: SMESG000043150.1 (SMESG000043150.1)

HSP 1 Score: 185.652 bits (470), Expect = 3.848e-56
Identity = 111/252 (44.05%), Postives = 158/252 (62.70%), Query Frame = 1 
Query:   97 LCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGDHPIQDLNVGDIISDQLSHEEQLIIAEHLPIIIDLLHNLEIYSKMFISLVESLKLYKTNFSEINFQKILFSN----STESKELFEIFSINIQNITKDYIHDFQDIAXXXXXXXXXXXXXXXXXXXXXEAYKTRLTNEIKLKEHYDLITNFIYCYECLEYLRSIFYHSSLFFNIANNRFQQHSFEKLIDKYFLNIHGK 840
            +CSIC D    NEYAI+ PCQH+FC+SCI+ W+ ENP CPLDRSD+  I I +N    +Q + V DI+ DQ+S  +Q+++  HLP+II+L    EI S   IS+++ LK +K  F + NFQKILFS+    S ES +LF++FS N   ITK+Y +D Q+I   ++NQ   +N+ L  LDK+ E Y   L N  + +E++ LI  FI+C+EC   +  IF  +S  F   NN+   + F  LID Y+L   G+
Sbjct:    7 ICSICLDYNSDNEYAIVLPCQHRFCLSCIRSWVTENPCCPLDRSDITNILIHNNSFDHVQSVTVSDILVDQISKNKQILLENHLPLIINLFKEFEINSGQLISIIQLLKEFKDKFRDCNFQKILFSDSFLTSFESIQLFQLFSDNYLRITKEYKYDAQNINKQLENQTKAVNEILGGLDKRFEKY---LENRSEFEEYFKLIGRFIFCHECFNTMNRIFLENSKSFRFFNNKLSLNYFGSLIDNYYLKYIGE 255
[Close]
BLAST of Ring finger protein 145b vs. Planmine SMEST
Match: SMESG000016408.1 (SMESG000016408.1)

HSP 1 Score: 171.014 bits (432), Expect = 2.415e-48
Identity = 98/245 (40.00%), Postives = 143/245 (58.37%), Query Frame = 1 
Query:   85 EFDDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGDHPIQDLNVGDIISDQLSHEEQLIIAEHLPIIIDLLHNLEIYSKMFISLVESLKLYKTNFSEINFQKILFSNSTESKELFEIFSINIQNITKDYIHDFQDIAXXXXXXXXXXXXXXXXXXXXXEAYKTRLTNEIKLKEHYDLITNFIYCYECLEYLRSIFYHSSLFFNIANNRFQQHSFEKLIDKY 819
            E  ++CSICYD    NE+AI+ PCQHKFCV CIK W+IENP CP+DRS++  I I  N  H IQ + V DI++D +   +Q++I +HLPI++DLL     YS   +S++ SLK +   F+E NFQ IL   S ESK LF+IFS   Q I  ++  DF  +        + +    DIL+   + YK  L  +I  +E++ L+   +YCYEC   + S+F  ++  F   +     +   ++IDKY
Sbjct:    3 EITEVCSICYDDQLENEFAIVLPCQHKFCVPCIKTWLIENPSCPIDRSEVIKILIHCNCIHDIQIMFVSDILNDYIKKNKQILITKHLPILVDLLSMFTKYSDKLVSVILSLKDFIMEFTENNFQSILIFKSNESKSLFKIFSTRYQRIIGNFKKDFNILD---DYIEEPIEILNDILEVLEDKYKIYLEEKISFQEYHSLVIRILYCYECFTMMSSLFNRNAGAFRYLSKELDNYYLCRMIDKY 244
[Close]
BLAST of Ring finger protein 145b vs. Planmine SMEST
Match: SMESG000013345.1 (SMESG000013345.1)

HSP 1 Score: 142.51 bits (358), Expect = 2.539e-40
Identity = 92/253 (36.36%), Postives = 139/253 (54.94%), Query Frame = 1 
Query:   85 EFDDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGDHPIQDLNVGDIISDQLSHEEQLIIAEHLPIIIDLLHNLEIYSKMFISLVESLKLYKTN----FSEINFQKILFSNSTESKELFEIFSINIQNITKDYI-HDFQDIAXXXXXXXXXXXXXXXXXXXXXEAYKTRLTNEIKLKEHYDLITNFIYCYECLEYLRSIFYHSSLFFNIANNRFQQHSFEKLIDKYFLN 828
            E D +C+IC D    NE++++SPC HKFC SCIK WI ENP CP+DR D+  ISI  +    ++ ++V DI+ D L   ++ +I +HL  I   L N EIYS+  I   +SL   KTN    F E N Q +L   S ESK +   FSIN ++ITK+++ H+  +I       L     ++  ++   E Y+  L    +L+  Y  I     CY CL+ L  +F  SS+     N+  + +SF+++ D+Y L+
Sbjct:    3 ETDKVCNICLDDDLNNEFSVLSPCGHKFCFSCIKKWITENPCCPMDRRDISKISINFHAFRTVKTVSVTDILIDHLILVKKQLIKDHLSKIKSFLENFEIYSEKVILFSQSLMTLKTNILKSFHE-NIQNVLIFESNESKGILREFSINFRDITKEFLYHETYNIE----ECLKKQKIQISNINLSMEKYEKYLVGRPELQTFYKFIDIITICYTCLKELNRLFQRSSILLKYFNDEMENNSFDQIQDRYILS 250
[Close]
BLAST of Ring finger protein 145b vs. Planmine SMEST
Match: SMESG000013495.1 (SMESG000013495.1)

HSP 1 Score: 144.821 bits (364), Expect = 2.355e-39
Identity = 87/248 (35.08%), Postives = 137/248 (55.24%), Query Frame = 1 
Query:   91 DDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRSDLFTISITSNGDHPIQDLNVGDIISDQLSHEEQLIIAEHLPIIIDLLHNLEIYSKMFISLVESLKLYKTNFSE---INFQKILFSNSTESKELFEIFSINIQNITKDYIHDFQDIAXXXXXXXXXXXXXXXXXXXXXEAYKTRLTNEIKLKEHYDLITNFIYCYECLEYLRSIFYHSSLFFNIANNRFQQHSFEKLIDKYFL 825
            + LCSIC +    ++ +++SPC HKFC  CIK WI ENP CPLDR++   ISI  N    ++ ++V  I++D LS   + +  +HL  +  LL +     K +IS+ +SL+L KT+F +     F+ +L S+S ESK+L + FS+N    T  +  +FQD   + +     ++  +      NE+ K  L N ++  E Y  +    YCYEC ++L  IF  S  FF   N + + +SF++  DKY L
Sbjct:    3 EKLCSICLEENPKDQLSVLSPCGHKFCFPCIKTWITENPRCPLDRTEAMNISIYCNQGDAMKIISVAHILTDHLSQTTKHLREDHLSKLTVLLQDCNKNCKKYISITQSLQLIKTDFLKSLPTYFENVLNSDSEESKDLLKTFSVNFYETTAKFTKEFQD---SREYLSTQISSLMGHFKLFNESNKKYLENTLEFHECYKTMKYLNYCYECYQHLDFIFVKSVSFFKYVNEKLRNNSFDQSFDKYVL 247
The following BLAST results are available for this feature:
BLAST of Ring finger protein 145b vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 145b vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 145b vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG90141.966e-645.83gene:FBgn0028847 transcript:FBtr0343664[more]
CG90141.966e-645.83gene:FBgn0028847 transcript:FBtr0080579[more]
gol5.667e-631.87gene:FBgn0004919 transcript:FBtr0300178[more]
gol5.667e-631.87gene:FBgn0004919 transcript:FBtr0306330[more]
gol7.723e-639.58gene:FBgn0004919 transcript:FBtr0300179[more]
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BLAST of Ring finger protein 145b vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
si:dkeyp-86f7.41.953e-630.51si:dkeyp-86f7.4 [Source:ZFIN;Acc:ZDB-GENE-091204-2... [more]
si:ch211-59o9.108.646e-642.22si:ch211-59o9.10 [Source:ZFIN;Acc:ZDB-GENE-101206-... [more]
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BLAST of Ring finger protein 145b vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSXETT00000026890.17.940e-738.18pep primary_assembly:Xenopus_tropicalis_v9.1:6:494... [more]
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BLAST of Ring finger protein 145b vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 145b vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 145b vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 1
Match NameE-valueIdentityDescription
U3KK958.927e-640.00RING-type domain-containing protein OS=Ficedula al... [more]
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BLAST of Ring finger protein 145b vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 145b vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnf41l2.120e-643.48ring finger protein 41, like [Source:ZFIN;Acc:ZDB-... [more]
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BLAST of Ring finger protein 145b vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
YBR062C_mRNA7.668e-636.36Protein of unknown function that interacts with Ms... [more]
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BLAST of Ring finger protein 145b vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 145b vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ring finger protein 145b vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000023870.11.302e-13992.71SMESG000023870.1[more]
SMESG000043150.13.848e-5644.05SMESG000043150.1[more]
SMESG000016408.12.415e-4840.00SMESG000016408.1[more]
SMESG000013345.12.539e-4036.36SMESG000013345.1[more]
SMESG000013495.12.355e-3935.08SMESG000013495.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014425 ID=SMED30014425|Name=Ring finger protein 145b|organism=Schmidtea mediterranea sexual|type=transcript|length=946bp
GAATTTCAGAAAAATAGAATTATATCAAATTCATTCATTAATAAAAAGTC
ACTAATGTGATTAACGTTAAACTAATTAATGAATGAATTCGATGACCTTT
GTAGCATTTGTTATGATTGCTATAAAGTGAATGAATATGCAATTATTTCA
CCGTGTCAACATAAATTCTGTGTTTCGTGTATTAAAATATGGATAATTGA
GAATCCAATCTGTCCGTTGGATCGAAGTGATTTATTCACTATATCAATTA
CCTCAAATGGTGATCACCCAATTCAAGATCTCAATGTCGGAGACATAATA
AGCGATCAATTATCTCATGAAGAACAATTGATCATTGCAGAACATTTGCC
AATAATTATTGATCTTTTGCACAACCTTGAAATCTATTCAAAAATGTTTA
TTTCTTTAGTTGAATCTTTGAAACTATATAAAACAAACTTTTCAGAAATT
AACTTCCAAAAGATTTTATTTTCAAATTCTACAGAGTCAAAAGAGCTATT
CGAAATTTTTTCTATAAATATCCAAAATATTACAAAAGATTACATTCATG
ATTTTCAAGACATCGCCCTAAACATAAAGAACCAACTTGATCTACTAAAT
GACAAATTAGACATCCTAGATAAGAAAAATGAAGCGTATAAGACGCGATT
GACCAACGAAATCAAACTGAAAGAACATTACGATTTGATCACCAACTTTA
TTTATTGTTATGAATGTTTGGAATATTTACGTTCCATATTTTATCACAGT
TCTCTTTTCTTTAATATCGCAAATAATAGATTTCAACAACATTCTTTCGA
GAAACTCATTGACAAATATTTCCTTAACATACATGGGAAATAATAAATAA
TCTAAACATGGAAATTCCTATGTTAAAATTAACTAATAGAATAGTCAACT
GTATAGTTTTAAAATTTGCAACAATTTCAATAGACATAAATAAATT
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protein sequence of SMED30014425-orf-1

>SMED30014425-orf-1 ID=SMED30014425-orf-1|Name=SMED30014425-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=255bp
MNEFDDLCSICYDCYKVNEYAIISPCQHKFCVSCIKIWIIENPICPLDRS
DLFTISITSNGDHPIQDLNVGDIISDQLSHEEQLIIAEHLPIIIDLLHNL
EIYSKMFISLVESLKLYKTNFSEINFQKILFSNSTESKELFEIFSINIQN
ITKDYIHDFQDIALNIKNQLDLLNDKLDILDKKNEAYKTRLTNEIKLKEH
YDLITNFIYCYECLEYLRSIFYHSSLFFNIANNRFQQHSFEKLIDKYFLN
IHGK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR017907Znf_RING_CS
IPR001841Znf_RING
IPR013083Znf_RING/FYVE/PHD
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0003674molecular_function
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 58..85