RNA-binding protein with serine-rich domain

Overview
NameRNA-binding protein with serine-rich domain
Smed IDSMED30014413
Length (bp)1550
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RNA-binding protein with serine-rich domain (SMED30014413) t-SNE clustered cells

Violin plots show distribution of expression levels for RNA-binding protein with serine-rich domain (SMED30014413) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RNA-binding protein with serine-rich domain (SMED30014413) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RNA-binding protein with serine-rich domain (SMED30014413) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014413

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30014413SMESG000010413.1 SmedASXL_018989SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30014413SMESG000010413.1 SmedASXL_018989SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30014413SMESG000010413.1 dd_Smed_v4_1431_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014413SMESG000010413.1 dd_Smed_v4_1431_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014413SMESG000010413.1 dd_Smed_v4_1431_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30014413SMESG000010413.1 dd_Smed_v4_1431_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014413SMESG000010413.1 dd_Smed_v4_1431_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30014413SMESG000010413.1 dd_Smed_v4_1431_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30014413SMESG000010413.1 dd_Smed_v6_1431_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Human
Match: RNPS1 (RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080])

HSP 1 Score: 96.6709 bits (239), Expect = 1.127e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  164 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 234
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Human
Match: RNPS1 (RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080])

HSP 1 Score: 96.6709 bits (239), Expect = 1.609e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  164 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 234
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Human
Match: RNPS1 (RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080])

HSP 1 Score: 96.6709 bits (239), Expect = 1.609e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  164 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 234
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Human
Match: RNPS1 (RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080])

HSP 1 Score: 96.6709 bits (239), Expect = 1.609e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  164 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 234
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Human
Match: RNPS1 (RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080])

HSP 1 Score: 96.6709 bits (239), Expect = 1.609e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  164 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 234
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Celegans
Match: rnp-5 (RNP (RRM RNA binding domain) containing [Source:UniProtKB/TrEMBL;Acc:Q21155])

HSP 1 Score: 78.1814 bits (191), Expect = 9.469e-16
Identity = 30/69 (43.48%), Postives = 49/69 (71.01%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            +  L+RN+   HL+EIFS +G++K+V++P DRFH   +RG+ YVE+D    A+++I  M+ GQ+DG  +
Sbjct:  137 IKNLSRNVLKTHLEEIFSIYGAIKNVDLPPDRFHNHVHRGYGYVEYDNLEDAEKSIKHMDGGQIDGMAV 205
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Fly
Match: RnpS1 (gene:FBgn0037707 transcript:FBtr0082066)

HSP 1 Score: 92.8189 bits (229), Expect = 3.231e-20
Identity = 39/71 (54.93%), Postives = 52/71 (73.24%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            HV +LTRN+T  H+ EIFS++G VK+VE P DRFHP F RG A+VE+  P   + A+  M+ GQ+DGQEI+
Sbjct:  222 HVGRLTRNVTKDHVFEIFSSFGDVKNVEFPVDRFHPNFGRGVAFVEYATPEDCESAMKHMDGGQIDGQEIT 292
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Fly
Match: CG34334 (gene:FBgn0263829 transcript:FBtr0112536)

HSP 1 Score: 73.559 bits (179), Expect = 2.082e-13
Identity = 30/70 (42.86%), Postives = 42/70 (60.00%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            H+  LTR +T  H+ EIF  +G++  V+ P DRF     RG+A+VE+  P     AI  MN GQ+DG+ I
Sbjct:  538 HIKGLTRQVTKEHITEIFGHFGALTAVDFPMDRFQGRQGRGYAFVEYSRPEDCASAIKHMNGGQIDGKLI 607
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Fly
Match: SC35 (gene:FBgn0265298 transcript:FBtr0306252)

HSP 1 Score: 49.2914 bits (116), Expect = 1.714e-6
Identity = 25/69 (36.23%), Postives = 38/69 (55.07%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   T   L+ +F   G V  + +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   27 VDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRE-SRGFAFVRFYDKRDAEDALEAMDGRMLDGREL 94
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Fly
Match: SC35 (gene:FBgn0265298 transcript:FBtr0302910)

HSP 1 Score: 49.2914 bits (116), Expect = 1.714e-6
Identity = 25/69 (36.23%), Postives = 38/69 (55.07%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   T   L+ +F   G V  + +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   27 VDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRE-SRGFAFVRFYDKRDAEDALEAMDGRMLDGREL 94
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Fly
Match: SC35 (gene:FBgn0265298 transcript:FBtr0089899)

HSP 1 Score: 49.2914 bits (116), Expect = 1.714e-6
Identity = 25/69 (36.23%), Postives = 38/69 (55.07%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   T   L+ +F   G V  + +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   27 VDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRE-SRGFAFVRFYDKRDAEDALEAMDGRMLDGREL 94
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Zebrafish
Match: rnps1 (RNA binding protein S1, serine-rich domain [Source:NCBI gene;Acc:327020])

HSP 1 Score: 97.0561 bits (240), Expect = 5.597e-22
Identity = 35/71 (49.30%), Postives = 57/71 (80.28%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            ++ +LTRN+T  H++EIF+T+G +K +++PSDR HP  ++G+AYVE++ P  AQ+A+  M+ GQ+DGQEI+
Sbjct:  140 YLGRLTRNVTKDHIQEIFATYGKIKMIDMPSDRLHPNVSKGYAYVEYESPEDAQKALKHMDGGQIDGQEIT 210
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Zebrafish
Match: rnps1 (RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080])

HSP 1 Score: 97.0561 bits (240), Expect = 5.597e-22
Identity = 35/71 (49.30%), Postives = 57/71 (80.28%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            ++ +LTRN+T  H++EIF+T+G +K +++PSDR HP  ++G+AYVE++ P  AQ+A+  M+ GQ+DGQEI+
Sbjct:  140 YLGRLTRNVTKDHIQEIFATYGKIKMIDMPSDRLHPNVSKGYAYVEYESPEDAQKALKHMDGGQIDGQEIT 210
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Zebrafish
Match: rnps1 (pep chromosome:GRCz11:CHR_ALT_CTG3_1_31:9437481:9444722:-1 gene:ENSDARG00000015853.10 transcript:ENSDART00000128731.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:rnps1)

HSP 1 Score: 95.9005 bits (237), Expect = 6.087e-22
Identity = 35/71 (49.30%), Postives = 57/71 (80.28%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            ++ +LTRN+T  H++EIF+T+G +K +++PSDR HP  ++G+AYVE++ P  AQ+A+  M+ GQ+DGQEI+
Sbjct:  140 YLGRLTRNVTKDHIQEIFATYGKIKMIDMPSDRLHPNVSKGYAYVEYESPEDAQKALKHMDGGQIDGQEIT 210
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Zebrafish
Match: cirbpb (cold inducible RNA binding protein b [Source:ZFIN;Acc:ZDB-GENE-030131-5841])

HSP 1 Score: 52.373 bits (124), Expect = 1.868e-7
Identity = 25/70 (35.71%), Postives = 41/70 (58.57%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
             +  L+ + T   L+E FS +G++  V+V  DR   + +RGF +V F+ P  A+ A+  MN  Q+DG+ I
Sbjct:    8 FIGGLSYDTTEQSLEEAFSKYGTIAKVDVIRDR-ETDRSRGFGFVTFENPEDAKDAMAAMNGKQVDGRMI 76
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Zebrafish
Match: cirbpb (cold inducible RNA binding protein b [Source:ZFIN;Acc:ZDB-GENE-030131-5841])

HSP 1 Score: 51.9878 bits (123), Expect = 3.925e-7
Identity = 25/69 (36.23%), Postives = 41/69 (59.42%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            +  L+ + T   L+E FS +G++  V+V  DR   + +RGF +V F+ P  A+ A+  MN  Q+DG+ I
Sbjct:   26 IGGLSYDTTEQSLEEAFSKYGTIAKVDVIRDR-ETDRSRGFGFVTFENPEDAKDAMAAMNGKQVDGRMI 93
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Xenopus
Match: mapk8ip1 (mitogen-activated protein kinase 8 interacting protein 1 [Source:Xenbase;Acc:XB-GENE-478437])

HSP 1 Score: 97.4413 bits (241), Expect = 5.687e-22
Identity = 36/71 (50.70%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P DR+HP  ++G+AYVEF+ P  A++A+  M+ GQ+DGQEI+
Sbjct:  143 HIGRLTRNVTKDHILEIFSTYGKIKMIDMPVDRYHPHLSKGYAYVEFEAPEEAEKALKHMDGGQIDGQEIT 213
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Xenopus
Match: mapk8ip1 (mitogen-activated protein kinase 8 interacting protein 1 [Source:Xenbase;Acc:XB-GENE-478437])

HSP 1 Score: 97.4413 bits (241), Expect = 1.003e-21
Identity = 36/71 (50.70%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P DR+HP  ++G+AYVEF+ P  A++A+  M+ GQ+DGQEI+
Sbjct:  176 HIGRLTRNVTKDHILEIFSTYGKIKMIDMPVDRYHPHLSKGYAYVEFEAPEEAEKALKHMDGGQIDGQEIT 246
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Xenopus
Match: mapk8ip1 (mitogen-activated protein kinase 8 interacting protein 1 [Source:Xenbase;Acc:XB-GENE-478437])

HSP 1 Score: 96.6709 bits (239), Expect = 2.410e-21
Identity = 36/71 (50.70%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P DR+HP  ++G+AYVEF+ P  A++A+  M+ GQ+DGQEI+
Sbjct:  167 HIGRLTRNVTKDHILEIFSTYGKIKMIDMPVDRYHPHLSKGYAYVEFEAPEEAEKALKHMDGGQIDGQEIT 237
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Xenopus
Match: srsf2 (serine/arginine-rich splicing factor 2 [Source:NCBI gene;Acc:394953])

HSP 1 Score: 49.2914 bits (116), Expect = 4.125e-6
Identity = 25/69 (36.23%), Postives = 39/69 (56.52%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   +   L+ +F  +G V  V +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   18 VDNLTYRTSPETLRRVFEKYGRVGDVYIPRDRYTKE-SRGFAFVRFHDKRDAEDAMDAMDGAVLDGREL 85
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Xenopus
Match: srsf2 (serine/arginine-rich splicing factor 2 [Source:NCBI gene;Acc:394953])

HSP 1 Score: 49.2914 bits (116), Expect = 4.990e-6
Identity = 25/69 (36.23%), Postives = 39/69 (56.52%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   +   L+ +F  +G V  V +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   18 VDNLTYRTSPETLRRVFEKYGRVGDVYIPRDRYTKE-SRGFAFVRFHDKRDAEDAMDAMDGAVLDGREL 85
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Mouse
Match: Rnps1 (ribonucleic acid binding protein S1 [Source:MGI Symbol;Acc:MGI:97960])

HSP 1 Score: 96.6709 bits (239), Expect = 1.105e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  164 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 234
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Mouse
Match: Rnps1 (ribonucleic acid binding protein S1 [Source:MGI Symbol;Acc:MGI:97960])

HSP 1 Score: 96.6709 bits (239), Expect = 1.105e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  164 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 234
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Mouse
Match: Rnps1 (ribonucleic acid binding protein S1 [Source:MGI Symbol;Acc:MGI:97960])

HSP 1 Score: 95.9005 bits (237), Expect = 1.205e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  141 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 211
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Mouse
Match: Srsf2 (serine/arginine-rich splicing factor 2 [Source:MGI Symbol;Acc:MGI:98284])

HSP 1 Score: 48.9062 bits (115), Expect = 4.637e-6
Identity = 25/69 (36.23%), Postives = 39/69 (56.52%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   +   L+ +F  +G V  V +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   18 VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKE-SRGFAFVRFHDKRDAEDAMDAMDGAVLDGREL 85
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Mouse
Match: Srsf2 (serine/arginine-rich splicing factor 2 [Source:MGI Symbol;Acc:MGI:98284])

HSP 1 Score: 48.9062 bits (115), Expect = 4.637e-6
Identity = 25/69 (36.23%), Postives = 39/69 (56.52%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   +   L+ +F  +G V  V +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   18 VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKE-SRGFAFVRFHDKRDAEDAMDAMDGAVLDGREL 85
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. UniProt/SwissProt
Match: sp|Q3KPW1|RNP1B_XENLA (RNA-binding protein with serine-rich domain 1-B OS=Xenopus laevis OX=8355 GN=rnps1-b PE=2 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 2.566e-21
Identity = 36/71 (50.70%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P DR+HP  ++G+AYVEF+ P  A++A+  M+ GQ+DGQEI+
Sbjct:  141 HIGRLTRNVTKDHILEIFSTYGKIKMIDMPVDRYHPHLSKGYAYVEFEAPEEAEKALKHMDGGQIDGQEIT 211
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. UniProt/SwissProt
Match: sp|Q5XG24|RNP1A_XENLA (RNA-binding protein with serine-rich domain 1-A OS=Xenopus laevis OX=8355 GN=rnps1-a PE=2 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 2.992e-21
Identity = 36/71 (50.70%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P DR+HP  ++G+AYVEF+ P  A++A+  M+ GQ+DGQEI+
Sbjct:  141 HIGRLTRNVTKDHILEIFSTYGKIKMIDMPVDRYHPHLSKGYAYVEFEAPEEAEKALKHMDGGQIDGQEIT 211
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. UniProt/SwissProt
Match: sp|Q28E41|RNPS1_XENTR (RNA-binding protein with serine-rich domain 1 OS=Xenopus tropicalis OX=8364 GN=rnps1 PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 3.150e-21
Identity = 36/71 (50.70%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P DR+HP  ++G+AYVEF+ P  A++A+  M+ GQ+DGQEI+
Sbjct:  167 HIGRLTRNVTKDHILEIFSTYGKIKMIDMPVDRYHPHLSKGYAYVEFEAPEEAEKALKHMDGGQIDGQEIT 237
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. UniProt/SwissProt
Match: sp|Q6PG31|RNPS1_DANRE (RNA-binding protein with serine-rich domain 1 OS=Danio rerio OX=7955 GN=rnps1 PE=2 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 4.562e-21
Identity = 35/71 (49.30%), Postives = 57/71 (80.28%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            ++ +LTRN+T  H++EIF+T+G +K +++PSDR HP  ++G+AYVE++ P  AQ+A+  M+ GQ+DGQEI+
Sbjct:  140 YLGRLTRNVTKDHIQEIFATYGKIKMIDMPSDRLHPNVSKGYAYVEYESPEDAQKALKHMDGGQIDGQEIT 210
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. UniProt/SwissProt
Match: sp|Q6AYK1|RNPS1_RAT (RNA-binding protein with serine-rich domain 1 OS=Rattus norvegicus OX=10116 GN=Rnps1 PE=2 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 7.729e-21
Identity = 35/71 (49.30%), Postives = 56/71 (78.87%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H+ EIFST+G +K +++P +R HP  ++G+AYVEF+ P+ A++A+  M+ GQ+DGQEI+
Sbjct:  164 HIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEIT 234
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. TrEMBL
Match: W6V0Y9 (RNA-binding protein with serine-rich domain OS=Echinococcus granulosus OX=6210 GN=EGR_00522 PE=4 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 3.123e-22
Identity = 44/69 (63.77%), Postives = 55/69 (79.71%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            VTKL+RN+T AH+ EIFSTWG VK VE+PSD  HPEF+RGFAY++F  P +A  A+  MN GQ+DGQE+
Sbjct:  419 VTKLSRNVTQAHISEIFSTWGQVKAVEMPSDHMHPEFHRGFAYIDFTSPQAASDAVNYMNGGQIDGQEV 487
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. TrEMBL
Match: A0A068W956 (RNA recognition motif RNP 1 OS=Echinococcus granulosus OX=6210 GN=EgrG_000899300 PE=4 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 3.328e-22
Identity = 44/69 (63.77%), Postives = 55/69 (79.71%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            VTKL+RN+T AH+ EIFSTWG VK VE+PSD  HPEF+RGFAY++F  P +A  A+  MN GQ+DGQE+
Sbjct:  377 VTKLSRNVTQAHISEIFSTWGQVKAVEMPSDHMHPEFHRGFAYIDFTSPQAASDAVNYMNGGQIDGQEV 445
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. TrEMBL
Match: A0A068YDH2 (RNA recognition motif RNP 1 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000899300 PE=4 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 4.255e-22
Identity = 44/69 (63.77%), Postives = 55/69 (79.71%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            VTKL+RN+T AH+ EIFSTWG VK VE+PSD  HPEF+RGFAY++F  P +A  A+  MN GQ+DGQE+
Sbjct:  378 VTKLSRNVTQAHISEIFSTWGQVKAVEMPSDHMHPEFHRGFAYIDFTSPQAASDAVNYMNGGQIDGQEV 446
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. TrEMBL
Match: A0A4W6G8M0 (RNA binding protein S1, serine-rich domain OS=Lates calcarifer OX=8187 PE=4 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 9.717e-22
Identity = 41/71 (57.75%), Postives = 57/71 (80.28%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H++EIFST+G +K VE+P+DR HP  +RG+AYVEF+ P  AQ+A+  M+ GQ+DGQEIS
Sbjct:  135 HLGRLTRNVTKDHIQEIFSTYGKIKMVEMPTDRLHPHLSRGYAYVEFETPEEAQKALKHMDGGQIDGQEIS 205
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. TrEMBL
Match: A0A4W6G7Q7 (RNA binding protein S1, serine-rich domain OS=Lates calcarifer OX=8187 PE=4 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 1.692e-21
Identity = 41/71 (57.75%), Postives = 57/71 (80.28%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H++EIFST+G +K VE+P+DR HP  +RG+AYVEF+ P  AQ+A+  M+ GQ+DGQEIS
Sbjct:  143 HLGRLTRNVTKDHIQEIFSTYGKIKMVEMPTDRLHPHLSRGYAYVEFETPEEAQKALKHMDGGQIDGQEIS 213
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Cavefish
Match: rnps1 (RNA binding protein S1, serine-rich domain [Source:NCBI gene;Acc:327020])

HSP 1 Score: 92.8189 bits (229), Expect = 2.417e-20
Identity = 36/70 (51.43%), Postives = 54/70 (77.14%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            + +LTRN+T  H++EIFST+G +K +++P DR HP  +RG AY+EF+ P  AQ+A+  M+ GQ+DGQEI+
Sbjct:  145 LGRLTRNVTKDHIQEIFSTYGKIKIIDMPQDRLHPNLSRGHAYIEFETPEEAQKALKHMDGGQIDGQEIT 214
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Cavefish
Match: ENSAMXT00000035068.1 (RNA-binding protein with serine-rich domain 1-like [Source:NCBI gene;Acc:103024569])

HSP 1 Score: 90.8929 bits (224), Expect = 4.425e-20
Identity = 33/71 (46.48%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            ++ +LTRN+   H++EIFST+G +K +++P DR HP  ++G+AYVEF+  + A++A+  M+ GQ+DGQEI+
Sbjct:  134 YLGRLTRNVIKEHIQEIFSTYGKIKMIDMPVDRLHPHLSKGYAYVEFETADEAEKALRHMDGGQIDGQEIT 204
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Cavefish
Match: ENSAMXT00000048736.1 (RNA-binding protein with serine-rich domain 1-like [Source:NCBI gene;Acc:103024569])

HSP 1 Score: 91.2781 bits (225), Expect = 4.453e-20
Identity = 33/71 (46.48%), Postives = 55/71 (77.46%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            ++ +LTRN+   H++EIFST+G +K +++P DR HP  ++G+AYVEF+  + A++A+  M+ GQ+DGQEI+
Sbjct:  140 YLGRLTRNVIKEHIQEIFSTYGKIKMIDMPVDRLHPHLSKGYAYVEFETADEAEKALRHMDGGQIDGQEIT 210
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Cavefish
Match: ENSAMXT00000006493.2 (RNA-binding protein with serine-rich domain 1-like [Source:NCBI gene;Acc:103024569])

HSP 1 Score: 76.6406 bits (187), Expect = 2.207e-15
Identity = 28/65 (43.08%), Postives = 48/65 (73.85%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQL 837
            ++ +LTRN+   H++EIFST+G +K +++P DR HP  ++G+AYVEF+  + A++A+  M+ G L
Sbjct:  135 YLGRLTRNVIKEHIQEIFSTYGKIKMIDMPVDRLHPHLSKGYAYVEFETADEAEKALRHMDGGVL 199
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Cavefish
Match: cirbpb (cold inducible RNA binding protein b [Source:ZFIN;Acc:ZDB-GENE-030131-5841])

HSP 1 Score: 51.2174 bits (121), Expect = 6.140e-7
Identity = 24/69 (34.78%), Postives = 42/69 (60.87%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            +  L+ + T   L++ FS +G++  V+V  DR   + +RGF +V F+ P+ A+ A+V MN   +DG+ I
Sbjct:   48 IGGLSYDTTEQSLEDAFSKYGTIAKVDVIRDR-ETDRSRGFGFVTFENPDDAKDAMVAMNGKSIDGRMI 115
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Sea Lamprey
Match: srsf2b (serine and arginine rich splicing factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-2420])

HSP 1 Score: 48.9062 bits (115), Expect = 6.747e-7
Identity = 26/70 (37.14%), Postives = 38/70 (54.29%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
             V  LT   +   L+  F  +G V  V +P DRF  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   11 QVDNLTYRTSPEMLRRSFEKYGDVGDVYIPRDRFTRE-SRGFAFVRFYDKRDAEDAMDAMDGKMLDGREL 79
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Nematostella
Match: EDO44931 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUM9])

HSP 1 Score: 77.411 bits (189), Expect = 1.087e-17
Identity = 34/71 (47.89%), Postives = 52/71 (73.24%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            +V  LTRN+   H++EIFS +G VK V++P+DR +   +RGFAYVE+ +P   ++A+  M+ GQ+DGQEI+
Sbjct:    4 YVAHLTRNVNKDHVQEIFSVYGRVKTVDLPTDRTN-NLSRGFAYVEYVDPEECEKALKHMDGGQIDGQEIA 73
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Nematostella
Match: EDO29859 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S877])

HSP 1 Score: 49.2914 bits (116), Expect = 2.267e-7
Identity = 26/69 (37.68%), Postives = 40/69 (57.97%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   T+  LK++F  +G +  + +P DR   E +RGFA+V F E   A+ A+  M+   LDG+E+
Sbjct:   20 VDNLTYRTTVEDLKQVFKKYGDLGDIYIPRDRNTHE-SRGFAFVRFYEKRDAEDAMDCMDRHLLDGREV 87
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Nematostella
Match: EDO40056 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S877])

HSP 1 Score: 49.2914 bits (116), Expect = 2.267e-7
Identity = 26/69 (37.68%), Postives = 40/69 (57.97%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   T+  LK++F  +G +  + +P DR   E +RGFA+V F E   A+ A+  M+   LDG+E+
Sbjct:   20 VDNLTYRTTVEDLKQVFKKYGDLGDIYIPRDRNTHE-SRGFAFVRFYEKRDAEDAMDCMDRHLLDGREV 87
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Nematostella
Match: EDO29715 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2V2])

HSP 1 Score: 45.8246 bits (107), Expect = 1.273e-6
Identity = 25/70 (35.71%), Postives = 40/70 (57.14%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
             V  L  +I  A L+  F  +G+V  V++ SD+F    ++GF +VE      AQ+AI E+N G ++G+ I
Sbjct:    4 FVGSLPFSIEEADLRGFFEEYGAVDSVKIISDKFTGR-SKGFGFVEMPNDAEAQKAIDELNGGTVEGRTI 72
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Medaka
Match: rnps1 (RNA binding protein with serine rich domain 1 [Source:NCBI gene;Acc:101174024])

HSP 1 Score: 93.9745 bits (232), Expect = 1.099e-21
Identity = 37/71 (52.11%), Postives = 54/71 (76.06%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H++EIFST+G +K V++P +R  P   +GFAYVEF+ P  AQ+A+  M+ GQ+DGQEI+
Sbjct:  124 HLGRLTRNVTKEHIQEIFSTYGKIKAVDMPVERLFPNLTKGFAYVEFETPEEAQKALKHMDGGQIDGQEIT 194
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Medaka
Match: rnps1 (RNA binding protein with serine rich domain 1 [Source:NCBI gene;Acc:101174024])

HSP 1 Score: 94.7449 bits (234), Expect = 2.251e-21
Identity = 37/71 (52.11%), Postives = 54/71 (76.06%), Query Frame = 1 
Query:  643 HVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEIS 855
            H+ +LTRN+T  H++EIFST+G +K V++P +R  P   +GFAYVEF+ P  AQ+A+  M+ GQ+DGQEI+
Sbjct:  130 HLGRLTRNVTKEHIQEIFSTYGKIKAVDMPVERLFPNLTKGFAYVEFETPEEAQKALKHMDGGQIDGQEIT 200
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Medaka
Match: srsf2a (serine/arginine-rich splicing factor 2 [Source:NCBI gene;Acc:100049528])

HSP 1 Score: 49.6766 bits (117), Expect = 2.233e-6
Identity = 25/69 (36.23%), Postives = 39/69 (56.52%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   +   L+ +F  +G V  V +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   18 VDNLTYRTSPETLRRVFEKYGRVGDVYIPRDRYSKE-SRGFAFVRFFDKRDAEDAMDAMDGALLDGREL 85
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Medaka
Match: srsf2a (serine/arginine-rich splicing factor 2 [Source:NCBI gene;Acc:100049528])

HSP 1 Score: 49.6766 bits (117), Expect = 2.233e-6
Identity = 25/69 (36.23%), Postives = 39/69 (56.52%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   +   L+ +F  +G V  V +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   18 VDNLTYRTSPETLRRVFEKYGRVGDVYIPRDRYSKE-SRGFAFVRFFDKRDAEDAMDAMDGALLDGREL 85
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Medaka
Match: ENSORLT00000001514.2 (serine/arginine-rich splicing factor 2 [Source:NCBI gene;Acc:101163660])

HSP 1 Score: 49.2914 bits (116), Expect = 2.462e-6
Identity = 24/69 (34.78%), Postives = 39/69 (56.52%), Query Frame = 1 
Query:  646 VTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEI 852
            V  LT   +   L+ +F  +G V  + +P DR+  E +RGFA+V F +   A+ A+  M+   LDG+E+
Sbjct:   18 VDNLTYRTSPETLRYVFEKYGRVGDIYIPRDRYTKE-SRGFAFVRFHDKRDAEDAMDAMDGALLDGREL 85
[Close]
BLAST of RNA-binding protein with serine-rich domain vs. Planmine SMEST
Match: SMESG000010413.1 (SMESG000010413.1)

HSP 1 Score: 337.035 bits (863), Expect = 8.667e-112
Identity = 289/290 (99.66%), Postives = 290/290 (100.00%), Query Frame = 1 
Query:   67 MPETKTDRNKSNKEVSNATNREKDKSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPKKVRADXXXXXXXXXXXXXXXXDVRPENQSNKYKEKPKTQKPSDMPVPRDSRPNKEDNKVKHEKTKSDYFKETEVSTGKTAEKLIDXXXXXXXXXXXXXXXXXXXHVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEISXXXXXXXXXXHEKDRPRRLSRDRVMDN 936
            MPETKTDRNKSNKEVSNATNREKDKSRKVNNVKRNKKRSSSSASGSSTSSTTSSSSNSSSGSSSGSSSSSSSSSSNSSTSRSSSPSPKKVRADKKVINKKPEVKKPEIKDVRPENQSNKYKEKPKTQKPSDMPVPRDSRPNKE+NKVKHEKTKSDYFKETEVSTGKTAEKLIDKVVEKPKSEEKIPKKSNKIHVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEISVVEVPVPRVEHEKDRPRRLSRDRVMDN
Sbjct:    1 MPETKTDRNKSNKEVSNATNREKDKSRKVNNVKRNKKRSSSSASGSSTSSTTSSSSNSSSGSSSGSSSSSSSSSSNSSTSRSSSPSPKKVRADKKVINKKPEVKKPEIKDVRPENQSNKYKEKPKTQKPSDMPVPRDSRPNKEENKVKHEKTKSDYFKETEVSTGKTAEKLIDKVVEKPKSEEKIPKKSNKIHVTKLTRNITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIVEMNNGQLDGQEISVVEVPVPRVEHEKDRPRRLSRDRVMDN 290
The following BLAST results are available for this feature:
BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RNPS11.127e-2149.30RNA binding protein with serine rich domain 1 [Sou... [more]
RNPS11.609e-2149.30RNA binding protein with serine rich domain 1 [Sou... [more]
RNPS11.609e-2149.30RNA binding protein with serine rich domain 1 [Sou... [more]
RNPS11.609e-2149.30RNA binding protein with serine rich domain 1 [Sou... [more]
RNPS11.609e-2149.30RNA binding protein with serine rich domain 1 [Sou... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnp-59.469e-1643.48RNP (RRM RNA binding domain) containing [Source:U... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RnpS13.231e-2054.93gene:FBgn0037707 transcript:FBtr0082066[more]
CG343342.082e-1342.86gene:FBgn0263829 transcript:FBtr0112536[more]
SC351.714e-636.23gene:FBgn0265298 transcript:FBtr0306252[more]
SC351.714e-636.23gene:FBgn0265298 transcript:FBtr0302910[more]
SC351.714e-636.23gene:FBgn0265298 transcript:FBtr0089899[more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnps15.597e-2249.30RNA binding protein S1, serine-rich domain [Source... [more]
rnps15.597e-2249.30RNA binding protein with serine rich domain 1 [Sou... [more]
rnps16.087e-2249.30pep chromosome:GRCz11:CHR_ALT_CTG3_1_31:9437481:94... [more]
cirbpb1.868e-735.71cold inducible RNA binding protein b [Source:ZFIN;... [more]
cirbpb3.925e-736.23cold inducible RNA binding protein b [Source:ZFIN;... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mapk8ip15.687e-2250.70mitogen-activated protein kinase 8 interacting pro... [more]
mapk8ip11.003e-2150.70mitogen-activated protein kinase 8 interacting pro... [more]
mapk8ip12.410e-2150.70mitogen-activated protein kinase 8 interacting pro... [more]
srsf24.125e-636.23serine/arginine-rich splicing factor 2 [Source:NCB... [more]
srsf24.990e-636.23serine/arginine-rich splicing factor 2 [Source:NCB... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rnps11.105e-2149.30ribonucleic acid binding protein S1 [Source:MGI Sy... [more]
Rnps11.105e-2149.30ribonucleic acid binding protein S1 [Source:MGI Sy... [more]
Rnps11.205e-2149.30ribonucleic acid binding protein S1 [Source:MGI Sy... [more]
Srsf24.637e-636.23serine/arginine-rich splicing factor 2 [Source:MGI... [more]
Srsf24.637e-636.23serine/arginine-rich splicing factor 2 [Source:MGI... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q3KPW1|RNP1B_XENLA2.566e-2150.70RNA-binding protein with serine-rich domain 1-B OS... [more]
sp|Q5XG24|RNP1A_XENLA2.992e-2150.70RNA-binding protein with serine-rich domain 1-A OS... [more]
sp|Q28E41|RNPS1_XENTR3.150e-2150.70RNA-binding protein with serine-rich domain 1 OS=X... [more]
sp|Q6PG31|RNPS1_DANRE4.562e-2149.30RNA-binding protein with serine-rich domain 1 OS=D... [more]
sp|Q6AYK1|RNPS1_RAT7.729e-2149.30RNA-binding protein with serine-rich domain 1 OS=R... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
W6V0Y93.123e-2263.77RNA-binding protein with serine-rich domain OS=Ech... [more]
A0A068W9563.328e-2263.77RNA recognition motif RNP 1 OS=Echinococcus granul... [more]
A0A068YDH24.255e-2263.77RNA recognition motif RNP 1 OS=Echinococcus multil... [more]
A0A4W6G8M09.717e-2257.75RNA binding protein S1, serine-rich domain OS=Late... [more]
A0A4W6G7Q71.692e-2157.75RNA binding protein S1, serine-rich domain OS=Late... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnps12.417e-2051.43RNA binding protein S1, serine-rich domain [Source... [more]
ENSAMXT00000035068.14.425e-2046.48RNA-binding protein with serine-rich domain 1-like... [more]
ENSAMXT00000048736.14.453e-2046.48RNA-binding protein with serine-rich domain 1-like... [more]
ENSAMXT00000006493.22.207e-1543.08RNA-binding protein with serine-rich domain 1-like... [more]
cirbpb6.140e-734.78cold inducible RNA binding protein b [Source:ZFIN;... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
srsf2b6.747e-737.14serine and arginine rich splicing factor 2b [Sourc... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO449311.087e-1747.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO298592.267e-737.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO400562.267e-737.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO297151.273e-635.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rnps11.099e-2152.11RNA binding protein with serine rich domain 1 [Sou... [more]
rnps12.251e-2152.11RNA binding protein with serine rich domain 1 [Sou... [more]
srsf2a2.233e-636.23serine/arginine-rich splicing factor 2 [Source:NCB... [more]
srsf2a2.233e-636.23serine/arginine-rich splicing factor 2 [Source:NCB... [more]
ENSORLT00000001514.22.462e-634.78serine/arginine-rich splicing factor 2 [Source:NCB... [more]
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BLAST of RNA-binding protein with serine-rich domain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000010413.18.667e-11299.66SMESG000010413.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014413 ID=SMED30014413|Name=RNA-binding protein with serine-rich domain|organism=Schmidtea mediterranea sexual|type=transcript|length=1550bp
GAATGCTATAAGAGTTGTATGTTTAAATATTAAAATGGTGATAAATTGAG
TATTTTTAGCTTTAGTATGCCTGAAACGAAAACTGATAGGAATAAAAGTA
ATAAAGAAGTTTCAAATGCCACAAATAGAGAAAAGGATAAATCTAGGAAA
GTAAATAATGTTAAAAGAAATAAAAAAAGATCCAGTAGTAGTGCATCAGG
TTCATCGACAAGCTCAACTACTAGTTCATCATCAAACAGTAGTTCTGGTA
GCAGTAGTGGTTCCAGCTCATCGAGTTCAAGTTCTTCATCTAATTCTTCT
ACTAGTAGAAGTTCTTCTCCATCTCCAAAAAAAGTACGTGCAGATAAAAA
AGTAATTAATAAAAAGCCAGAAGTTAAAAAACCCGAAATCAAAGATGTTC
GACCTGAAAATCAAAGTAATAAGTATAAGGAGAAACCCAAAACACAAAAG
CCTTCTGATATGCCTGTGCCGAGGGATAGTAGACCTAATAAAGAAGATAA
TAAAGTTAAGCACGAGAAAACAAAGTCAGATTATTTCAAAGAAACAGAAG
TAAGTACTGGTAAAACAGCTGAAAAACTCATAGACAAAGTTGTTGAAAAG
CCGAAATCCGAAGAAAAAATTCCCAAAAAATCCAATAAAATTCACGTAAC
TAAACTTACGAGAAACATAACGATGGCTCATTTGAAGGAAATTTTTTCGA
CGTGGGGCTCAGTAAAGCACGTCGAAGTTCCCAGTGATAGATTCCATCCG
GAATTCAACCGGGGATTTGCTTATGTCGAGTTCGATGAGCCGAATTCCGC
CCAGCAGGCGATCGTGGAGATGAATAACGGCCAATTGGACGGACAGGAAA
TATCTGTGGTTGAAGTTCCAGTTCCTCGGGTCGAGCACGAGAAGGATCGT
CCCAGACGGCTGTCAAGAGATCGAGTAATGGACAATAGGCGATTCCGATC
GCCTCCGAGACGACACGTACGCAGCCCAGTTCGTCAGCGGTCACCGCCGC
AGCGACGGAGCTTGCCTGGTCGGCGCAATTCACCGTTCCGTCGTCGCAAC
GTCAGATCACCACCTAGAAGGCCACGCAGAGAGAGCCCGAGGCCTCGTCG
ACGCAGCAGAACTCCATTGAGTCCAAACCGTCGAAACGGCAAAGAAAGAG
GAGATCGGAAATCGCCGGTTCCAGTTCGACGAAGATCAAAATCGTCTACT
TCGAGGTCTCGATAATTTAGCGAAATAAATGTTACCGTTTCTATTTTAAT
ATTGCGAAATATATTTATAAACAATCGATTGTTCGATTTAAATTGGTTGG
TGCGTGTTGCTATGGTAATGATTCTGTGCTTGCGTTGTTCCGTTACGGGT
TTTATCTGGTTGCTATGGTAATGCTCAACAAAGGGTGCCGATTTACTGGT
TGTTTTTTCAAGACTTAATTGGATGTAATCAAATATTTTCCCACTTGTAC
CTTATGAGAACTTGAGCACCGTTATTGAGTTATGATGTTGGGTGTTTGTG
GCAGTATAATATTCGTATACTGTTTTCCCCAGCCTTGGAACTCATTTTCA
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protein sequence of SMED30014413-orf-1

>SMED30014413-orf-1 ID=SMED30014413-orf-1|Name=SMED30014413-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=383bp
MPETKTDRNKSNKEVSNATNREKDKSRKVNNVKRNKKRSSSSASGSSTSS
TTSSSSNSSSGSSSGSSSSSSSSSSNSSTSRSSSPSPKKVRADKKVINKK
PEVKKPEIKDVRPENQSNKYKEKPKTQKPSDMPVPRDSRPNKEDNKVKHE
KTKSDYFKETEVSTGKTAEKLIDKVVEKPKSEEKIPKKSNKIHVTKLTRN
ITMAHLKEIFSTWGSVKHVEVPSDRFHPEFNRGFAYVEFDEPNSAQQAIV
EMNNGQLDGQEISVVEVPVPRVEHEKDRPRRLSRDRVMDNRRFRSPPRRH
VRSPVRQRSPPQRRSLPGRRNSPFRRRNVRSPPRRPRRESPRPRRRSRTP
LSPNRRNGKERGDRKSPVPVRRRSKSSTSRSR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0003676nucleic acid binding
GO:0000166nucleotide binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR034201RNPS1_RRM
IPR035979RBD_domain_sf
IPR000504RRM_dom
IPR012677Nucleotide-bd_a/b_plait_sf
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000504RNA recognition motif domainSMARTSM00360rrm1_1coord: 191..265
e-value: 1.6E-16
score: 70.9
IPR000504RNA recognition motif domainPFAMPF00076RRM_1coord: 193..262
e-value: 7.3E-16
score: 57.8
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 190..264
score: 15.289
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 187..271
e-value: 9.0E-20
score: 72.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 36..86
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 353..370
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 319..352
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 87..164
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 268..294
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..29
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..164
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 268..382
NoneNo IPR availablePANTHERPTHR15481RIBONUCLEIC ACID BINDING PROTEIN S1coord: 9..380
IPR034201RNPS1, RNA recognition motifCDDcd12365RRM_RNPS1coord: 192..263
e-value: 7.91386E-32
score: 113.034
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 187..291