Mannosyl phosphorylinositol ceramide synthase SUR1

Overview
NameMannosyl phosphorylinositol ceramide synthase SUR1
Smed IDSMED30014403
Length (bp)1453
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Mannosyl phosphorylinositol ceramide synthase SUR1 (SMED30014403) t-SNE clustered cells

Violin plots show distribution of expression levels for Mannosyl phosphorylinositol ceramide synthase SUR1 (SMED30014403) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Mannosyl phosphorylinositol ceramide synthase SUR1 (SMED30014403) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Mannosyl phosphorylinositol ceramide synthase SUR1 (SMED30014403) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014403

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30014403SMESG000046033.1 Contig3050newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014403SMESG000046033.1 Contig3050uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30014403 dd_Smed_v4_9783_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014403 dd_Smed_v4_9783_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30014403 dd_Smed_v4_9783_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014403 dd_Smed_v4_9783_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30014403 dd_Smed_v6_9783_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30014403 dd_Smed_v4_9783_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
ventral epidermis progenitor cellSMED30014403 dd_Smed_v4_9783_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. UniProt/SwissProt
Match: sp|P38287|CSH1_YEAST (Mannosyl phosphorylinositol ceramide synthase CSH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CSH1 PE=1 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 1.509e-17
Identity = 55/182 (30.22%), Postives = 90/182 (49.45%), Query Frame = 3 
Query:  453 IPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQK---PMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTH------ILIQTGPLKLTKVYISYNK 971
            IPK+IH  YK+N IP+Q+V   + C++++ D  +I W+D  +   +  E+   L  + SY       ++ +D  RYFI+  +GGIY+DLD  C++   P+  +P     FL + +               N  MG VPRH FF  ++K +             I+  TGPL ++ V+  Y +
Sbjct:   62 IPKIIHQTYKTNDIPEQWVKGRQKCIDLHPDYTYILWTDEMSDTFIKQEYPWFLDTFRSY----EYPIERADAIRYFILSHYGGIYIDLDDGCERRLDPLLKVP----AFLRKTSPTG----------VSNDVMGSVPRHPFFLKVIKSLKHYKKNWYIPYMTIMGSTGPLFISVVWKQYKR 225
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. UniProt/SwissProt
Match: sp|P33300|SUR1_YEAST (Mannosyl phosphorylinositol ceramide synthase SUR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SUR1 PE=1 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 5.043e-17
Identity = 53/182 (29.12%), Postives = 89/182 (48.90%), Query Frame = 3 
Query:  453 IPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQK---PMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDS------THILIQTGPLKLTKVYISYNK 971
            IPK+IH  YK+  IP+ +    + C++++ D ++I W+D  AY+ +  E+   L  + +Y       ++ +D  RYFI+  +GG+Y+DLD  C++   P+   P     FL + +               N  MG VPRH FF   +K +   D         I+  TGPL L+ ++  Y +
Sbjct:   55 IPKIIHQTYKTEDIPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENY----KYPIERADAIRYFILSHYGGVYIDLDDGCERKLDPLLAFP----AFLRKTSP----------LGVSNDVMGSVPRHPFFLKALKSLKHYDKYWFIPYMTIMGSTGPLFLSVIWKQYKR 218
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. UniProt/SwissProt
Match: sp|Q10323|IMT3_SCHPO (Inositol phosphoceramide mannosyltransferase 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC17G8.11c PE=1 SV=1)

HSP 1 Score: 82.0333 bits (201), Expect = 1.074e-15
Identity = 45/180 (25.00%), Postives = 95/180 (52.78%), Query Frame = 3 
Query:  450 SIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTH------ILIQTGPLKLTKVYISYNK 971
            +IPK+IH  +K+N IP+++V   + C++++ D +++ W+D +  + +  ++   L  Y SY      +++ +D+ RYFI+ K+GGIY+DLD  C + +  + ++   ++ R +               N+ MG    H F   +V+ + +    +      ++  TGPL L+ ++ ++ K
Sbjct:   56 AIPKIIHQTWKTNEIPEKWVGAQKSCIDLHPDYEYVLWTDESMREFIATDYPWFLTQYDSY----PYNIERADVVRYFILYKYGGIYLDLDVGCNRTLDPL-LHYPAWVRRTSPSGIS----------NNVMGFAKGHPFLLQVVRNLPRFAFNYHFPYLTVMYSTGPLFLSIIWSAWRK 220
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. UniProt/SwissProt
Match: sp|Q9UT67|IMT2_SCHPO (Inositol phosphoceramide mannosyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=SPCC4F11.04c PE=3 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 1.145e-14
Identity = 42/182 (23.08%), Postives = 93/182 (51.10%), Query Frame = 3 
Query:  453 IPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTH------ILIQTGPLKLTKVYISYNKSLA 980
            IPK+IH  +K+  +P+ +    + C++++ D ++I W+D  +   + + +   L     YF     +++ +D+ RYF++  +GG Y+DLD  C++ +  + +    ++ R +               N  MG VP H +F ++++ + K+  ++      I++ TGPL ++ ++  Y + L 
Sbjct:   82 IPKIIHQTWKTTEVPEGWKGAQQSCIDLHPDYEYILWTDEMSRNFIADNYPWFL----PYFDAYPFNVQRADVIRYFVLYHYGGNYIDLDDGCRQRLDSL-LYYPVWVRRTDP----------VGVSNDVMGSVPHHPYFELIIQNLEKNAKSYWLPYLTIMLSTGPLSISFLWEKYKRQLP 248
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. UniProt/SwissProt
Match: sp|O14084|IMT1_SCHPO (Inositol phosphoceramide mannosyltransferase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=imt1 PE=3 SV=2)

HSP 1 Score: 73.559 bits (179), Expect = 4.862e-13
Identity = 51/198 (25.76%), Postives = 93/198 (46.97%), Query Frame = 3 
Query:  399 ISFENVQKFADENKYFNSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDA---QFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTH------ILIQTGPLKLTKVYISY 965
            +S  +V            IP++IH ++K   IP+++ + V  C   + D    QFI W+D      +   +   + V+ SY      +++  D +RYFI+  +GG+YMDLD  C+KPM  + ++++ F+    E    I Y+      N +    P+H F +  +  +SK +  +      + +  GPL L+  +  Y
Sbjct:   46 LSLSDVSDDTSAPGEMEKIPRVIHQLWKDENIPERWSNTVNSCRRQHPDENGWQFILWTDEKIMSFMNENYSWFMPVFHSY----PYNIQKFDAARYFILYHYGGVYMDLDIGCKKPMDPL-LSKATFILPSTEP---IGYS------NDWFAATPKHPFLYQAIHNLSKFNHRYFTKYPTVFLSAGPLFLSYQFCKY 229
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. TrEMBL
Match: A0A1I8I557 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031525g1 PE=4 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 5.686e-37
Identity = 93/275 (33.82%), Postives = 144/275 (52.36%), Query Frame = 3 
Query:  453 IPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTH-ILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVE--PYVEKNCKGKIEGQ-------WKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYSASKSRIEKLTHINRIN 1247
            IP+++H V +S  +  +Y   +  C  +N +  +I W D  A +L++ EF  D   Y + ++K    LK SD  RY I+  FGG+Y DLD +C KP       E+CFL +EN   + I +N + +AMNS MGC P H F   LV +++KS S   +++ TGPL LTK    +    A   ++D   ++ + D   FSP V+    +   C+ +  GQ       W  +GC+ L ++   ++   +  + VH FMHLG+ + K R     HI RIN
Sbjct:   38 IPRILHQVGESELVFAEYSFAIESCRRLNPNWTYILWRDKDA-ELLIKEFFPDF--YRTQYAKYTNRLKKSDSIRYIILYLFGGLYADLDVECMKPFSPDLDEEACFLDQENPAQSHIFWNKERSAMNSVMGCRPGHPFMLDLVSRMAKSPSNQAVMLSTGPLMLTKALDEWT---AQGSQRDWADSVRLMDPDIFSPHVDNADILMDACRKRF-GQPANDGELWVDRGCRDL-QFGGLKDNFTERTVAVHWFMHLGWYSLKER----EHIQRIN 300
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. TrEMBL
Match: A0A267G0Y6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012114g1 PE=4 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 1.662e-36
Identity = 87/281 (30.96%), Postives = 142/281 (50.53%), Query Frame = 3 
Query:  447 NSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFI----PINE-----------SCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLV-KQISKSDSTHILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVE-----------PYVEKN-CKGKIEGQ--WKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYS 1199
            + IPK++HYV+KS  + D Y  F++ C++ N D Q +FWSD  + +L+ + +   +  Y SY  +    L+ SD  RY I+ KFGG+Y+D+D +C+KP   +    P+ E           S FL  E  + TRILY   + AMNS MG  P H FF + + + +      H  + TGP  LT +Y  +    A      A + +++  +   SP+++           P++ K     K+EG+  W+  GC  L+    + +++    + VH F+HLGY 
Sbjct:   76 SGIPKILHYVFKSEQVFDSYKPFIKSCLDQNPDWQVLFWSDSHSEKLIADHYARFIHKYRSYRDR----LEKSDSVRYMILHKFGGVYLDMDVECRKPFSRLFTQPPVQERFAVASATAAPSAFLGEERREQTRILYGYSYCAMNSMMGSRPGHPFFQLAIDRMLGMPMLAHARLTTGPDFLTGLYRMWLNCSAGPASCQAKEPVLLYPARLVSPLMDTSLVNWESKCRPFLSKGKPDAKLEGRRKWEAMGCSQLVANGWNYDQTDDTTVAVHRFLHLGYG 352
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. TrEMBL
Match: A0A1I8GMC1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031525g2 PE=4 SV=1)

HSP 1 Score: 147.902 bits (372), Expect = 1.718e-36
Identity = 92/275 (33.45%), Postives = 144/275 (52.36%), Query Frame = 3 
Query:  453 IPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTH-ILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVE--PYVEKNCKGKIEGQ-------WKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYSASKSRIEKLTHINRIN 1247
            IP+++H V +S  +  +Y   +  C  +N +  +I W D  A +L++ EF  D   Y + ++K    LK SD  RY I+  FGG+Y DLD +C KP       E+CFL +EN   + I +N + +AMNS MGC P H F   LV ++++S S   +++ TGPL LTK    +    A   ++D   ++ + D   FSP V+    +   C+ +  GQ       W  +GC+ L ++   ++   +  + VH FMHLG+ + K R     HI RIN
Sbjct:   38 IPRILHQVGESELVFAEYSFAIESCRRLNPNWTYILWRDKDA-ELLIKEFFPDF--YRTQYAKYTNRLKKSDSIRYIILYLFGGLYADLDVECMKPFSPDLDEEACFLDQENPAQSHIFWNKERSAMNSVMGCRPGHPFMLDLVSRMAESPSNQAVMLSTGPLMLTKALDEWT---AQGSQRDWADSVRLMDPDIFSPHVDNADILMDACRKRF-GQPANDGELWVDRGCRDL-QFGGLKDNFTERTVAVHWFMHLGWYSLKER----EHIQRIN 300
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. TrEMBL
Match: A0A267H5Y6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000626g1 PE=4 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 1.878e-36
Identity = 87/281 (30.96%), Postives = 142/281 (50.53%), Query Frame = 3 
Query:  447 NSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFI----PINE-----------SCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLV-KQISKSDSTHILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVE-----------PYVEKN-CKGKIEGQ--WKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYS 1199
            + IPK++HYV+KS  + D Y  F++ C++ N D Q +FWSD  + +L+ + +   +  Y SY  +    L+ SD  RY I+ KFGG+Y+D+D +C+KP   +    P+ E           S FL  E  + TRILY   + AMNS MG  P H FF + + + +      H  + TGP  LT +Y  +    A      A + +++  +   SP+++           P++ K     K+EG+  W+  GC  L+    + +++    + VH F+HLGY 
Sbjct:   76 SGIPKILHYVFKSEQVFDSYKPFIKSCLDQNPDWQVLFWSDSHSEKLIADHYARFIHKYRSYRDR----LEKSDSVRYMILHKFGGVYLDMDVECRKPFSRLFTQPPVQESLAVASATVAPSAFLGEERREQTRILYGYSYCAMNSVMGSRPGHPFFQLAIDRMLGMPMLAHARLTTGPDFLTGLYRMWLNCSAGPASCQAKEPVLLYPARLVSPLMDTSLVNWESKCRPFLSKGKPDAKLEGRRKWEAMGCSQLVANGWNYDQTDDTTVAVHRFLHLGYG 352
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. TrEMBL
Match: A0A267FYT6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015448g3 PE=4 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 2.122e-36
Identity = 87/281 (30.96%), Postives = 142/281 (50.53%), Query Frame = 3 
Query:  447 NSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFI----PINE-----------SCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLV-KQISKSDSTHILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVEPYV---EKNCK---------GKIEGQ--WKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYS 1199
            + IPK++HYV+KS  + D Y  F++ C++ N D Q +FWSD  + +L+ + +   +  Y SY  +    L+ SD  RY I+ KFGG+Y+D+D +C+KP   +    P+ E           S FL  E  + TRILY   + AMNS MG  P H FF + + + +      H  + TGP  LT +Y  +    A      A + +++  +   SP+++  +   E  C+          K+EG+  W+  GC  L+    + +++    + VH F+HLGY 
Sbjct:   90 SGIPKILHYVFKSEQVFDSYKPFIKSCLDQNPDWQVLFWSDSHSEKLIADHYARFIHKYRSYRDR----LEKSDSVRYMILHKFGGVYLDMDVECRKPFSRLFTQPPVQESLAVASATAAPSAFLGEERREQTRILYGYSYCAMNSMMGSRPGHPFFQLAIDRMLGMPMLAHARLTTGPDFLTGLYRMWLNCSAGPASCQAKEPVLLYPARLVSPLMDTSLVNWESKCRPFFSKGKPDAKLEGRRKWEAMGCSQLVANGWNYDQTDDTTVAVHRFLHLGYG 366
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Yeast
Match: CSH1 (Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p; CSH1 has a paralog, SUR1, that arose from the whole genome duplication [Source:SGD;Acc:S000000365])

HSP 1 Score: 87.8113 bits (216), Expect = 2.173e-19
Identity = 55/182 (30.22%), Postives = 90/182 (49.45%), Query Frame = 3 
Query:  453 IPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQK---PMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTH------ILIQTGPLKLTKVYISYNK 971
            IPK+IH  YK+N IP+Q+V   + C++++ D  +I W+D  +   +  E+   L  + SY       ++ +D  RYFI+  +GGIY+DLD  C++   P+  +P     FL + +               N  MG VPRH FF  ++K +             I+  TGPL ++ V+  Y +
Sbjct:   62 IPKIIHQTYKTNDIPEQWVKGRQKCIDLHPDYTYILWTDEMSDTFIKQEYPWFLDTFRSY----EYPIERADAIRYFILSHYGGIYIDLDDGCERRLDPLLKVP----AFLRKTSPTG----------VSNDVMGSVPRHPFFLKVIKSLKHYKKNWYIPYMTIMGSTGPLFISVVWKQYKR 225
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Yeast
Match: SUR1 (Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p; SUR1 has a paralog, CSH1, that arose from the whole genome duplication [Source:SGD;Acc:S000005978])

HSP 1 Score: 86.2705 bits (212), Expect = 7.262e-19
Identity = 53/182 (29.12%), Postives = 89/182 (48.90%), Query Frame = 3 
Query:  453 IPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQK---PMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDS------THILIQTGPLKLTKVYISYNK 971
            IPK+IH  YK+  IP+ +    + C++++ D ++I W+D  AY+ +  E+   L  + +Y       ++ +D  RYFI+  +GG+Y+DLD  C++   P+   P     FL + +               N  MG VPRH FF   +K +   D         I+  TGPL L+ ++  Y +
Sbjct:   55 IPKIIHQTYKTEDIPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENY----KYPIERADAIRYFILSHYGGVYIDLDDGCERKLDPLLAFP----AFLRKTSP----------LGVSNDVMGSVPRHPFFLKALKSLKHYDKYWFIPYMTIMGSTGPLFLSVIWKQYKR 218
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Planmine SMEST
Match: SMESG000065880.1 (SMESG000065880.1)

HSP 1 Score: 296.59 bits (758), Expect = 2.185e-97
Identity = 151/327 (46.18%), Postives = 213/327 (65.14%), Query Frame = 3 
Query:  285 LFVFCFILYTCNFENPYIFINMESTENKTLNNSVVIRMISFENVQKFADENKYFNSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTHILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVEPYVEKNCKGKIEGQWKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYSASKSRIEKLTHINRINENIKVV 1265
            +F++  +L  C F    + IN  + E +T++ S    ++S+  VQ++A      N +PK+IHYVYK+ YIP QY   V++C+EIN+  +FIFWSDF  Y  VL  F  +  ++SSYFSKS+ESLKISD+ RYFI+ KFGGIYMDLDT+CQKP++    N SC LS+E  + TRIL+N  + AMNSFM  +P H FF  L+ +++ +DS HIL QTGP  +T    SYNK   +    D  K +I++DS  +SP  E Y+E +C G   G WK+KGCK L E++K Q    K+A V+HLFMHLGY+ +K  +  L ++ +  +NI +V
Sbjct:    4 IFIYFAVLIQCKFSCGQL-INFSNGECQTMSTS---DILSYGKVQQYA------NGVPKIIHYVYKTAYIPSQYSPHVKNCLEINKGVKFIFWSDFTTYGFVLKHFQQNAKLFSSYFSKSVESLKISDVIRYFILFKFGGIYMDLDTQCQKPLEEAMKNGSCILSQEINEQTRILWNAPYLAMNSFMATIPDHEFFQYLIGKLTVADSAHILYQTGPFFMTNALESYNK--LVRNVTDQSKLVILADSYLYSPFTERYLEGHCGGNPVGVWKVKGCKTLAEHRKQQKIRTKDAFVIHLFMHLGYNFAKHAVINLDYVCKTFKNITIV 318
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Planmine SMEST
Match: SMESG000052405.1 (SMESG000052405.1)

HSP 1 Score: 290.426 bits (742), Expect = 7.807e-95
Identity = 140/299 (46.82%), Postives = 202/299 (67.56%), Query Frame = 3 
Query:  369 TLNNSVVIRMISFENVQKFADENKYFNSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTHILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVEPYVEKNCKGKIEGQWKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYSASKSRIEKLTHINRINENIKVV 1265
            T+N + V  + S  ++ +F   ++Y N IPK+IHYVYK+ YIP QY   V++C++IN+DA+F+FW+DF AY+ ++N FH  + +YSSYFSKS  SLKISD+ RYFI+ KFGGIYMD DT+CQKP     +N SC LS+E  + TRIL+NL + AMNSFM  +P H+FF  L+ +++ +DS+ IL QTGP  L+    +Y K   +T  KD  K++ ++D  ++SP  E Y+E  CK    G WKI+GCK L  +++ Q   +  A+VVHLFMHLGY  +K  I+ L ++ R   N+ ++
Sbjct:   28 TINKNGVCEIFSTNSLMEFGRRHQYANGIPKIIHYVYKTAYIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSTHSLKISDVIRYFILYKFGGIYMDFDTRCQKPFNIAMLNGSCILSQEVLEQTRILWNLPYLAMNSFMAAIPDHDFFKFLIGKLTLADSSFILSQTGPFLLSNSLDAYKK--IITNTKDVKKSVTLADPYFYSPHTENYLESLCKSP-SGFWKIQGCKDLGSHRQQQKLKMNEAVVVHLFMHLGYEFAKGNIKLLDNVCRTFTNMTII 323
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Planmine SMEST
Match: SMESG000065849.1 (SMESG000065849.1)

HSP 1 Score: 286.96 bits (733), Expect = 1.607e-93
Identity = 148/327 (45.26%), Postives = 211/327 (64.53%), Query Frame = 3 
Query:  285 LFVFCFILYTCNFENPYIFINMESTENKTLNNSVVIRMISFENVQKFADENKYFNSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTHILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVEPYVEKNCKGKIEGQWKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYSASKSRIEKLTHINRINENIKVV 1265
            +F++  +L  C F    + IN  + E +T++ S    ++S+  VQ++A      N +PK+IHYVYK+ YIP QY   V++C+EIN+ A+FI WSDF AY  VL  F  +  ++SSYFSKS+ESLKISD+ RYFI+ KFGGIYMDLDT+CQKP++      SC LS+E  + TRIL+N  + AMNSFM  +P H FF  L+ +++ ++S  I+ QTGP  +T    SYNK   +    D  K +I++DS  +SP  E Y+E +C G   G WK+KGCK L E++K Q    K+A V+HLFMHLGY+ +K  +  L +  +  +NI +V
Sbjct:    4 IFIYFAVLIQCKFSCGQL-INFPNGECQTMSTS---DILSYGKVQQYA------NGVPKIIHYVYKTAYIPSQYSPHVKNCLEINKGAKFILWSDFTAYGFVLKHFQQNAKLFSSYFSKSVESLKISDVIRYFILFKFGGIYMDLDTQCQKPLEEAMKKGSCILSQEINEQTRILWNAPYAAMNSFMATIPDHEFFKYLIGKLTVANSFEIVYQTGPFFMTNALESYNK--LVRNVTDQSKLVILADSYLYSPFTEHYLEGHCYGNPVGDWKVKGCKTLAEHRKQQKIRTKDAFVIHLFMHLGYNFAKHAVINLDYACKTLKNITIV 318
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Planmine SMEST
Match: SMESG000054245.1 (SMESG000054245.1)

HSP 1 Score: 283.878 bits (725), Expect = 2.517e-92
Identity = 135/299 (45.15%), Postives = 201/299 (67.22%), Query Frame = 3 
Query:  369 TLNNSVVIRMISFENVQKFADENKYFNSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTHILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVEPYVEKNCKGKIEGQWKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYSASKSRIEKLTHINRINENIKVV 1265
            T+N + V  + S   + +F   ++Y N IPK+IHY+YK+ +IP QY   V++C++IN+DA+F+FW+DF AY+ ++N FH  + +YSSYFSKS  SLKISD+ RYFI+ KFGGIYMD DT+CQKP     +N SC LS+E  +  RI++NL + AMNSFM  +P H+FF  L+ +++ +DS+ IL QTGP  L+    +Y K   +T  KD  K++ ++D  ++SP  E Y+E  C+    G WKI+GCK L  +++ Q   + +A+VVHLFMHLGY  +K  I+ L ++ R   N+ ++
Sbjct:   28 TINKNGVCEIFSTNLLMEFGRRHQYANGIPKIIHYIYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSTHSLKISDVIRYFILYKFGGIYMDFDTRCQKPFDMAMLNGSCILSQEVHEQKRIMWNLPYLAMNSFMAAIPDHDFFKYLIGKLTLADSSFILSQTGPFLLSNSLDAYKK--IVTNTKDVKKSVTLADPYFYSPHTENYLESLCRSP-SGFWKIQGCKDLGSHRQQQKLKMNDAVVVHLFMHLGYEFAKGNIKLLDNVCRTFTNMTII 323
[Close]
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Planmine SMEST
Match: SMESG000054422.1 (SMESG000054422.1)

HSP 1 Score: 283.493 bits (724), Expect = 3.369e-92
Identity = 136/299 (45.48%), Postives = 200/299 (66.89%), Query Frame = 3 
Query:  369 TLNNSVVIRMISFENVQKFADENKYFNSIPKLIHYVYKSNYIPDQYVSFVRHCVEINRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYFIILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAMNSFMGCVPRHNFFHVLVKQISKSDSTHILIQTGPLKLTKVYISYNKSLALTERKDAMKNIIVSDSSYFSPIVEPYVEKNCKGKIEGQWKIKGCKGLIEYKKHQNESIKNAIVVHLFMHLGYSASKSRIEKLTHINRINENIKVV 1265
            T+N + V  + S  ++ +F   ++Y N IPK+IHYVYK+ +IP QY   V++C++IN+DA+F+FW+DF AY+ ++N FH  + +YSSYFSKS  SLKISD+ RYFI+ KFGGIYMD DT+CQK      +N SC LS+E  + TRIL+NL + AMNSFM  +P H+FF  L+ +++ +DS+ IL QTGP  L+    +Y     +T  KD  K++ ++D  ++SP  E Y+E  C+    G WKI+GCK L  +++ Q   +  A+VVHLFMHLGY  +K  I+ L ++ R   N+ ++
Sbjct:   28 TINKNGVCEIFSTNSLMEFGRRHQYVNGIPKIIHYVYKTAFIPTQYSPHVKNCMDINKDAKFVFWADFTAYRFIINNFHNYVKLYSSYFSKSTHSLKISDVIRYFILYKFGGIYMDFDTRCQKSFDMAMLNGSCILSQEVHEQTRILWNLPYLAMNSFMAAIPDHDFFKYLIGKLTLADSSFILSQTGPFLLSNSLDAYKN--IVTNTKDVKKSVTLADPYFYSPHTENYLESLCRSP-SGFWKIQGCKDLGSHRQQQKLKMNEAVVVHLFMHLGYEFAKGNIKLLDNVCRTFTNMTII 323
The following BLAST results are available for this feature:
BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P38287|CSH1_YEAST1.509e-1730.22Mannosyl phosphorylinositol ceramide synthase CSH1... [more]
sp|P33300|SUR1_YEAST5.043e-1729.12Mannosyl phosphorylinositol ceramide synthase SUR1... [more]
sp|Q10323|IMT3_SCHPO1.074e-1525.00Inositol phosphoceramide mannosyltransferase 3 OS=... [more]
sp|Q9UT67|IMT2_SCHPO1.145e-1423.08Inositol phosphoceramide mannosyltransferase 2 OS=... [more]
sp|O14084|IMT1_SCHPO4.862e-1325.76Inositol phosphoceramide mannosyltransferase 1 OS=... [more]
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8I5575.686e-3733.82Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267G0Y61.662e-3630.96Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8GMC11.718e-3633.45Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267H5Y61.878e-3630.96Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FYT62.122e-3630.96Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
CSH12.173e-1930.22Mannosylinositol phosphorylceramide (MIPC) synthas... [more]
SUR17.262e-1929.12Mannosylinositol phosphorylceramide (MIPC) synthas... [more]
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Mannosyl phosphorylinositol ceramide synthase SUR1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000065880.12.185e-9746.18SMESG000065880.1[more]
SMESG000052405.17.807e-9546.82SMESG000052405.1[more]
SMESG000065849.11.607e-9345.26SMESG000065849.1[more]
SMESG000054245.12.517e-9245.15SMESG000054245.1[more]
SMESG000054422.13.369e-9245.48SMESG000054422.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014403 ID=SMED30014403|Name=Mannosyl phosphorylinositol ceramide synthase SUR1|organism=Schmidtea mediterranea sexual|type=transcript|length=1453bp
TCAATCATGTTACATAAAAAAAAATTACAAATTTTTTGTGTAAATTGAGT
TATTGTCTAATAAATTTTCATGGTTGAACACGTATTTGACAAGACTCTCA
CTATGAATGACAACCATATATTTTTGAGTATAAAAATAATAATTAAAGAA
AGATTACCAAGTTTCTATGATTAAAAAAGAACACTCCTAACATTTCCACC
GTTTTATTTGAAAGATTTGACAGTTATTAATTTATGAAGATCAAACGAAA
TATTTTCAAAAATTATTTTATATTAATTGGTGTTTTATTTGTGTTTTGTT
TTATTTTATATACATGCAACTTTGAAAATCCATATATATTCATAAACATG
GAGAGTACAGAAAATAAAACACTGAATAATTCAGTTGTAATCAGAATGAT
TTCATTTGAAAATGTTCAAAAATTTGCAGATGAAAACAAATATTTCAATT
CGATTCCAAAACTAATTCATTACGTCTACAAATCCAACTACATTCCGGAT
CAGTATGTTTCCTTCGTTCGGCATTGCGTGGAAATTAATAGAGATGCGCA
ATTTATTTTCTGGAGTGATTTTGCTGCTTACCAACTGGTTCTCAATGAGT
TCCATGTTGATCTCCTCGTGTACTCTAGCTATTTTTCCAAGTCATTAGAA
TCTTTGAAGATATCAGATATGTCCAGATATTTTATTATTTTAAAATTCGG
AGGAATTTATATGGATCTCGATACAAAATGTCAGAAACCAATGAAGTTTA
TTCCGATTAATGAATCTTGTTTCCTAAGTCGAGAGAATGAGGATAGTACT
CGCATTTTGTATAATTTAGACTTCAATGCCATGAACAGTTTCATGGGCTG
TGTGCCTAGGCATAACTTTTTTCACGTTTTAGTAAAACAAATATCGAAAT
CCGATTCAACGCACATTCTTATCCAAACGGGTCCTTTGAAGTTAACAAAG
GTTTACATCTCTTATAACAAGTCACTGGCGTTGACAGAAAGAAAGGACGC
CATGAAAAATATTATTGTGTCCGATTCATCATATTTTTCACCGATAGTTG
AACCATATGTTGAAAAAAATTGTAAAGGTAAAATCGAAGGTCAATGGAAA
ATTAAGGGTTGTAAAGGTTTAATCGAATACAAGAAACATCAAAACGAAAG
TATTAAAAATGCCATTGTGGTTCATTTGTTTATGCATCTGGGATACAGTG
CATCGAAATCTCGCATCGAAAAATTGACTCATATTAACAGAATAAATGAA
AATATAAAAGTTGTATTATTTAGTAATTCTAAATTAATTTTGATTATTCT
TAATTTATTCTTAAAACAAATTTTATGTAAGTTTTCAGAAACCGTTGTTA
AAGTATCATTTATCAGCGGTGACGCTTTTGTGATTTGGACGCTTCTAGGT
GTTGCACAATGAAGCGCTATATAATTATATTTAAAATTAATCGATGAGAT
CGG
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protein sequence of SMED30014403-orf-1

>SMED30014403-orf-1 ID=SMED30014403-orf-1|Name=SMED30014403-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=393bp
MKIKRNIFKNYFILIGVLFVFCFILYTCNFENPYIFINMESTENKTLNNS
VVIRMISFENVQKFADENKYFNSIPKLIHYVYKSNYIPDQYVSFVRHCVE
INRDAQFIFWSDFAAYQLVLNEFHVDLLVYSSYFSKSLESLKISDMSRYF
IILKFGGIYMDLDTKCQKPMKFIPINESCFLSRENEDSTRILYNLDFNAM
NSFMGCVPRHNFFHVLVKQISKSDSTHILIQTGPLKLTKVYISYNKSLAL
TERKDAMKNIIVSDSSYFSPIVEPYVEKNCKGKIEGQWKIKGCKGLIEYK
KHQNESIKNAIVVHLFMHLGYSASKSRIEKLTHINRINENIKVVLFSNSK
LILIILNLFLKQILCKFSETVVKVSFISGDAFVIWTLLGVAQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000418head
PLANA:0003503ventral epidermis progenitor cell
Vocabulary: INTERPRO
TermDefinition
IPR007577GlycoTrfase_DXD_sugar-bd_CS
IPR029044Nucleotide-diphossugar_trans
Vocabulary: molecular function
TermDefinition
GO:0000030mannosyltransferase activity
GO:0016740transferase activity
GO:0016757transferase activity, transferring glycosyl groups
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
GO:0005789endoplasmic reticulum membrane
GO:0005794Golgi apparatus
GO:0016020membrane
GO:0016021integral component of membrane
GO:0032588trans-Golgi network membrane
GO:0033106cis-Golgi network membrane
Vocabulary: biological process
TermDefinition
GO:0051999mannosyl-inositol phosphorylceramide biosynthetic process
GO:0097502mannosylation