F-BAR domain only protein 2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014362 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of F-BAR domain only protein 2 vs. Ensembl Human
Match: FCHO2 (FCH and mu domain containing endocytic adaptor 2 [Source:HGNC Symbol;Acc:HGNC:25180]) HSP 1 Score: 172.94 bits (437), Expect = 1.154e-43 Identity = 96/280 (34.29%), Postives = 152/280 (54.29%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
M F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + + + L ++++ Y+A+ +E +L K G R+IE+ K KKA D YK +EKY F+ KM E+ FQ+IE HL +K+ I S + ++ + + F TV++L++ F +SK TGK P FE+ +++
Sbjct: 1 MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTA 276 HSP 2 Score: 125.946 bits (315), Expect = 9.853e-29 Identity = 90/316 (28.48%), Postives = 163/316 (51.58%), Query Frame = 2
Query: 2126 PSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDI---NIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P+ + P +S+ + + +P+A+A TE+VNA F+ + T V +G + +SFP +++ F S + + F + SRL + LP ++ + Q D+ T D ++++ + L L PA+ ++NVD+++Y V++N G + P++++ W+ + + + L ++Y + P VA P+ N ++ +V DG MQSLPP+IWN++ +A W+L + +S S+++KF LS GP P + QF +EGS SGV ++ G +R+S K R +GRY+
Sbjct: 524 PTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGA-DPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAV-----LCFRVKNISRLEQI--LPNAQLVFSDPSQCDSNTKD---FWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSN----GIQSTPLNLATYWKCSAS-TTDLRVDYKYN-PEAMVA-------PSVLSN--------IQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYL 807
BLAST of F-BAR domain only protein 2 vs. Ensembl Human
Match: FCHO2 (FCH and mu domain containing endocytic adaptor 2 [Source:HGNC Symbol;Acc:HGNC:25180]) HSP 1 Score: 161.77 bits (408), Expect = 1.280e-42 Identity = 96/280 (34.29%), Postives = 152/280 (54.29%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
M F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + + + L ++++ Y+A+ +E +L K G R+IE+ K KKA D YK +EKY F+ KM E+ FQ+IE HL +K+ I S + ++ + + F TV++L++ F +SK TGK P FE+ +++
Sbjct: 1 MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTA 276
BLAST of F-BAR domain only protein 2 vs. Ensembl Human
Match: FCHO1 (FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002]) HSP 1 Score: 156.377 bits (394), Expect = 2.802e-38 Identity = 83/285 (29.12%), Postives = 154/285 (54.04%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQ 1009
F ++FWG+K+ GF+VLY ++K G S+ E DF+RE ++E++ +K+ KLSK N G+ P W+ + S+K + H+EL++ +Q +IK V +Y +EQ K K+ + T + +L S L ++R+ Y R ++ +L + + +++++ E K KKA + + +EKYN+ F+ KML+S FQ +E HL MK + ++ + + + F++ ++V+ LL F +SK TG+ P FE ++ ++ +++
Sbjct: 4 FGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQ----KEMDKAETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLR 284 HSP 2 Score: 96.2857 bits (238), Expect = 1.859e-19 Identity = 81/325 (24.92%), Postives = 157/325 (48.31%), Query Frame = 2
Query: 2087 SNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDV-HTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTD---DSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSL-PPSIWNSDLGRASWRL-DLSTNQSS--IKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISG 3037
+++ +E F S + + P + + S + +P+A AFTE V+A FR ++P + +G+L ++FP +++ F + + F L + + + +P + ++ +P+ ++ ++++ L + L P + ++NV ++RY + RP G + P+ +SA+WQ TL + + + Y ++ T V P+P N +I ++ G P L P + WN + R +WRL D+S S + + + +GP TP PV QF++EG+ SGV L++ G+ +R+S K R +
Sbjct: 594 ASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFR---GHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPV-----LSFRLVHTTAIEHFQP-----NADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFS---RP-GPQSVPLQLSAHWQCGATL-TQVSVEYGYRPGATAV------PTPLT--NVQI---------LLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATA 883
BLAST of F-BAR domain only protein 2 vs. Ensembl Human
Match: FCHO1 (FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002]) HSP 1 Score: 156.377 bits (394), Expect = 3.037e-38 Identity = 83/285 (29.12%), Postives = 154/285 (54.04%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQ 1009
F ++FWG+K+ GF+VLY ++K G S+ E DF+RE ++E++ +K+ KLSK N G+ P W+ + S+K + H+EL++ +Q +IK V +Y +EQ K K+ + T + +L S L ++R+ Y R ++ +L + + +++++ E K KKA + + +EKYN+ F+ KML+S FQ +E HL MK + ++ + + + F++ ++V+ LL F +SK TG+ P FE ++ ++ +++
Sbjct: 4 FGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQ----KEMDKAETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLR 284 HSP 2 Score: 101.679 bits (252), Expect = 3.320e-21 Identity = 83/328 (25.30%), Postives = 160/328 (48.78%), Query Frame = 2
Query: 2087 SNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDV-HTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTD---DSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSL-PPSIWNSDLGRASWRL-DLSTNQSS--IKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
+++ +E F S + + P + + S + +P+A AFTE V+A FR ++P + +G+L ++FP +++ F + + F L + + + +P + ++ +P+ ++ ++++ L + L P + ++NV ++RY + RP G + P+ +SA+WQ TL + + + Y ++ T V P+P N +I ++ G P L P + WN + R +WRL D+S S + + + +GP TP PV QF++EG+ SGV L++ G+ +R+S K R +G Y+
Sbjct: 594 ASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFR---GHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPV-----LSFRLVHTTAIEHFQP-----NADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFS---RP-GPQSVPLQLSAHWQCGATL-TQVSVEYGYRPGATAV------PTPLT--NVQI---------LLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYL 886
BLAST of F-BAR domain only protein 2 vs. Ensembl Human
Match: FCHO1 (FCH and mu domain containing endocytic adaptor 1 [Source:HGNC Symbol;Acc:HGNC:29002]) HSP 1 Score: 156.377 bits (394), Expect = 3.037e-38 Identity = 83/285 (29.12%), Postives = 154/285 (54.04%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQ 1009
F ++FWG+K+ GF+VLY ++K G S+ E DF+RE ++E++ +K+ KLSK N G+ P W+ + S+K + H+EL++ +Q +IK V +Y +EQ K K+ + T + +L S L ++R+ Y R ++ +L + + +++++ E K KKA + + +EKYN+ F+ KML+S FQ +E HL MK + ++ + + + F++ ++V+ LL F +SK TG+ P FE ++ ++ +++
Sbjct: 4 FGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQ----KEMDKAETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLR 284 HSP 2 Score: 101.679 bits (252), Expect = 3.320e-21 Identity = 83/328 (25.30%), Postives = 160/328 (48.78%), Query Frame = 2
Query: 2087 SNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDV-HTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTD---DSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSL-PPSIWNSDLGRASWRL-DLSTNQSS--IKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
+++ +E F S + + P + + S + +P+A AFTE V+A FR ++P + +G+L ++FP +++ F + + F L + + + +P + ++ +P+ ++ ++++ L + L P + ++NV ++RY + RP G + P+ +SA+WQ TL + + + Y ++ T V P+P N +I ++ G P L P + WN + R +WRL D+S S + + + +GP TP PV QF++EG+ SGV L++ G+ +R+S K R +G Y+
Sbjct: 594 ASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFR---GHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPV-----LSFRLVHTTAIEHFQP-----NADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFS---RP-GPQSVPLQLSAHWQCGATL-TQVSVEYGYRPGATAV------PTPLT--NVQI---------LLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYL 886
BLAST of F-BAR domain only protein 2 vs. Ensembl Celegans
Match: fcho-1 (FCH domain Only (FCH stands for Fes/CIP4 homology domain) [Source:UniProtKB/TrEMBL;Acc:Q9TXS0]) HSP 1 Score: 131.339 bits (329), Expect = 8.789e-31 Identity = 79/284 (27.82%), Postives = 149/284 (52.46%), Query Frame = 2
Query: 146 ETLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQIN--VNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKS 991
E L ++D+FWGDKH GF VL +N+K ++ +E F++E S+ED K+ N+ +++ + + S+ W K E + H+ L +N+Q + + V KY ++ +K K Q +L+ T+T L +A++ Y R E K+ K N ++I ++E K+ +A ++YK ++KY F++KM +SC FQ + ++ F+ F+ H ++ ++ F+++ + L D + F+K+KSTG P +FE++E+ + +
Sbjct: 4 EGLLYADHFWGDKHHGFQVLQENLKKSEETVAEVAQFVKERLSVEDEYVKAINRSVNKVSHYIQNGSSIDAMWLLTKGTMELMAEIHVMLVKNLQDLSREVLKYKEDVNRTRKELKQP--QVAEAVNLMQTTTTCLQKAKETYQHRCQELEKVKKETNVN---VKEISKVELKVARAREEYKSYVDKYELVREDFETKMSDSCKKFQTFDRSLYASIQQFMLLFANHSTEMSSASHQVAEQFKESIQHLNADEFVRKFVKTKSTGTEKPPRVLFEESENGQLPA 282
BLAST of F-BAR domain only protein 2 vs. Ensembl Celegans
Match: fcho-1 (FCH domain Only (FCH stands for Fes/CIP4 homology domain) [Source:UniProtKB/TrEMBL;Acc:Q9TXS0]) HSP 1 Score: 101.679 bits (252), Expect = 1.476e-21 Identity = 68/266 (25.56%), Postives = 135/266 (50.75%), Query Frame = 2
Query: 200 VLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQIN--VNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKS 991
VL +N+K ++ +E F++E S+ED K+ N+ +++ + + S+ W K E + H+ L +N+Q + + V KY ++ +K K Q +L+ T+T L +A++ Y R E K+ K N ++I ++E K+ +A ++YK ++KY F++KM +SC FQ + ++ F+ F+ H ++ ++ F+++ + L D + F+K+KSTG P +FE++E+ + +
Sbjct: 5 VLQENLKKSEETVAEVAQFVKERLSVEDEYVKAINRSVNKVSHYIQNGSSIDAMWLLTKGTMELMAEIHVMLVKNLQDLSREVLKYKEDVNRTRKELKQP--QVAEAVNLMQTTTTCLQKAKETYQHRCQELEKVKKETNVN---VKEISKVELKVARAREEYKSYVDKYELVREDFETKMSDSCKKFQTFDRSLYASIQQFMLLFANHSTEMSSASHQVAEQFKESIQHLNADEFVRKFVKTKSTGTEKPPRVLFEESENGQLPA 265
BLAST of F-BAR domain only protein 2 vs. Ensembl Fly
Match: CG8176 (gene:FBgn0037702 transcript:FBtr0334650) HSP 1 Score: 178.333 bits (451), Expect = 3.595e-45 Identity = 96/272 (35.29%), Postives = 160/272 (58.82%), Query Frame = 2
Query: 149 TLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFE 964
T+ F+D FWG+K+ G+DVLY NMK G+ +S E +FLRE ++E+ +K +KL+ + +S + P W ++ +EK ST H+++ Q + ++K V KY DE K KS K+ + QT + ++ + + RD+Y ++ E KL K +NG+ +D E++E+KLKK ++YK L++K+N +F+ +M ++C FQEIE HL QMK+F+S + L + + F++ ++VD LLE F+ +K TG P+ E
Sbjct: 2 TVDFNDYFWGEKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAHKAGTLNS-TFAPVWTILRTSAEKLSTLHLQMVQKLTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVAVQKLRDLYASKVQELEKLRK---DNGSH-KDAEKLESKLKKLQEEYKALLDKHNPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKPEMPELE 268 HSP 2 Score: 112.079 bits (279), Expect = 1.352e-24 Identity = 90/310 (29.03%), Postives = 150/310 (48.39%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRR---NEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLSTNQ-----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWE 3052
P L+I + IPLA+AF E ++A FR S + V SG +++SFP + N N A+ + F + L N+ +P K + QID S S ++ F + LRR N P + +FNVDI++Y V +P G+ + P + + W+ +S+ + ++++ N +AS + P V V +GS +QS P S W + R W D+S N +++++ L++GP TP + QF+ EG+ SG+ ++ G+ +R+S K R +SG+YV E
Sbjct: 829 PSPLTIGISDTIPLAVAFHEIIHAYFRGS-DESRCQVKVSGDMMLSFPAGIAGLLA----NNPNPAK-LGFRIKHVQNLENL--VPNGKLV--QIDRQQSSSVSTMLE-FNMGALTALLRRQAENNPTASYFNVDILKYQV--RTKP-GASSCPFQLVSYWKCE---SSYTALKVDYKYNNHAMASAS--------------PLLNVTLSVPVNGSVRNVQSKPHSAWLGESNRLVWNFTDISQNSQDGGVGTLRARLELNDGPSTPALLATQFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKYVCE 1107
BLAST of F-BAR domain only protein 2 vs. Ensembl Fly
Match: CG8176 (gene:FBgn0037702 transcript:FBtr0082065) HSP 1 Score: 178.333 bits (451), Expect = 3.595e-45 Identity = 96/272 (35.29%), Postives = 160/272 (58.82%), Query Frame = 2
Query: 149 TLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFE 964
T+ F+D FWG+K+ G+DVLY NMK G+ +S E +FLRE ++E+ +K +KL+ + +S + P W ++ +EK ST H+++ Q + ++K V KY DE K KS K+ + QT + ++ + + RD+Y ++ E KL K +NG+ +D E++E+KLKK ++YK L++K+N +F+ +M ++C FQEIE HL QMK+F+S + L + + F++ ++VD LLE F+ +K TG P+ E
Sbjct: 2 TVDFNDYFWGEKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAHKAGTLNS-TFAPVWTILRTSAEKLSTLHLQMVQKLTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVAVQKLRDLYASKVQELEKLRK---DNGSH-KDAEKLESKLKKLQEEYKALLDKHNPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKPEMPELE 268 HSP 2 Score: 112.079 bits (279), Expect = 1.352e-24 Identity = 90/310 (29.03%), Postives = 150/310 (48.39%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRR---NEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLSTNQ-----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWE 3052
P L+I + IPLA+AF E ++A FR S + V SG +++SFP + N N A+ + F + L N+ +P K + QID S S ++ F + LRR N P + +FNVDI++Y V +P G+ + P + + W+ +S+ + ++++ N +AS + P V V +GS +QS P S W + R W D+S N +++++ L++GP TP + QF+ EG+ SG+ ++ G+ +R+S K R +SG+YV E
Sbjct: 829 PSPLTIGISDTIPLAVAFHEIIHAYFRGS-DESRCQVKVSGDMMLSFPAGIAGLLA----NNPNPAK-LGFRIKHVQNLENL--VPNGKLV--QIDRQQSSSVSTMLE-FNMGALTALLRRQAENNPTASYFNVDILKYQV--RTKP-GASSCPFQLVSYWKCE---SSYTALKVDYKYNNHAMASAS--------------PLLNVTLSVPVNGSVRNVQSKPHSAWLGESNRLVWNFTDISQNSQDGGVGTLRARLELNDGPSTPALLATQFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKYVCE 1107
BLAST of F-BAR domain only protein 2 vs. Ensembl Fly
Match: CG8176 (gene:FBgn0037702 transcript:FBtr0334651) HSP 1 Score: 177.563 bits (449), Expect = 7.270e-45 Identity = 96/272 (35.29%), Postives = 160/272 (58.82%), Query Frame = 2
Query: 149 TLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFE 964
T+ F+D FWG+K+ G+DVLY NMK G+ +S E +FLRE ++E+ +K +KL+ + +S + P W ++ +EK ST H+++ Q + ++K V KY DE K KS K+ + QT + ++ + + RD+Y ++ E KL K +NG+ +D E++E+KLKK ++YK L++K+N +F+ +M ++C FQEIE HL QMK+F+S + L + + F++ ++VD LLE F+ +K TG P+ E
Sbjct: 2 TVDFNDYFWGEKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAHKAGTLNS-TFAPVWTILRTSAEKLSTLHLQMVQKLTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVAVQKLRDLYASKVQELEKLRK---DNGSH-KDAEKLESKLKKLQEEYKALLDKHNPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKPEMPELE 268 HSP 2 Score: 112.464 bits (280), Expect = 1.150e-24 Identity = 90/310 (29.03%), Postives = 150/310 (48.39%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRR---NEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLSTNQ-----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWE 3052
P L+I + IPLA+AF E ++A FR S + V SG +++SFP + N N A+ + F + L N+ +P K + QID S S ++ F + LRR N P + +FNVDI++Y V +P G+ + P + + W+ +S+ + ++++ N +AS + P V V +GS +QS P S W + R W D+S N +++++ L++GP TP + QF+ EG+ SG+ ++ G+ +R+S K R +SG+YV E
Sbjct: 916 PSPLTIGISDTIPLAVAFHEIIHAYFRGS-DESRCQVKVSGDMMLSFPAGIAGLLA----NNPNPAK-LGFRIKHVQNLENL--VPNGKLV--QIDRQQSSSVSTMLE-FNMGALTALLRRQAENNPTASYFNVDILKYQV--RTKP-GASSCPFQLVSYWKCE---SSYTALKVDYKYNNHAMASAS--------------PLLNVTLSVPVNGSVRNVQSKPHSAWLGESNRLVWNFTDISQNSQDGGVGTLRARLELNDGPSTPALLATQFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKYVCE 1194
BLAST of F-BAR domain only protein 2 vs. Ensembl Fly
Match: CG8176 (gene:FBgn0037702 transcript:FBtr0113207) HSP 1 Score: 177.563 bits (449), Expect = 7.270e-45 Identity = 96/272 (35.29%), Postives = 160/272 (58.82%), Query Frame = 2
Query: 149 TLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFE 964
T+ F+D FWG+K+ G+DVLY NMK G+ +S E +FLRE ++E+ +K +KL+ + +S + P W ++ +EK ST H+++ Q + ++K V KY DE K KS K+ + QT + ++ + + RD+Y ++ E KL K +NG+ +D E++E+KLKK ++YK L++K+N +F+ +M ++C FQEIE HL QMK+F+S + L + + F++ ++VD LLE F+ +K TG P+ E
Sbjct: 2 TVDFNDYFWGEKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAHKAGTLNS-TFAPVWTILRTSAEKLSTLHLQMVQKLTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVAVQKLRDLYASKVQELEKLRK---DNGSH-KDAEKLESKLKKLQEEYKALLDKHNPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKPEMPELE 268 HSP 2 Score: 112.464 bits (280), Expect = 1.150e-24 Identity = 90/310 (29.03%), Postives = 150/310 (48.39%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRR---NEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLSTNQ-----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWE 3052
P L+I + IPLA+AF E ++A FR S + V SG +++SFP + N N A+ + F + L N+ +P K + QID S S ++ F + LRR N P + +FNVDI++Y V +P G+ + P + + W+ +S+ + ++++ N +AS + P V V +GS +QS P S W + R W D+S N +++++ L++GP TP + QF+ EG+ SG+ ++ G+ +R+S K R +SG+YV E
Sbjct: 916 PSPLTIGISDTIPLAVAFHEIIHAYFRGS-DESRCQVKVSGDMMLSFPAGIAGLLA----NNPNPAK-LGFRIKHVQNLENL--VPNGKLV--QIDRQQSSSVSTMLE-FNMGALTALLRRQAENNPTASYFNVDILKYQV--RTKP-GASSCPFQLVSYWKCE---SSYTALKVDYKYNNHAMASAS--------------PLLNVTLSVPVNGSVRNVQSKPHSAWLGESNRLVWNFTDISQNSQDGGVGTLRARLELNDGPSTPALLATQFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKYVCE 1194
BLAST of F-BAR domain only protein 2 vs. Ensembl Fly
Match: CG8176 (gene:FBgn0037702 transcript:FBtr0334652) HSP 1 Score: 177.178 bits (448), Expect = 7.678e-45 Identity = 96/272 (35.29%), Postives = 160/272 (58.82%), Query Frame = 2
Query: 149 TLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFE 964
T+ F+D FWG+K+ G+DVLY NMK G+ +S E +FLRE ++E+ +K +KL+ + +S + P W ++ +EK ST H+++ Q + ++K V KY DE K KS K+ + QT + ++ + + RD+Y ++ E KL K +NG+ +D E++E+KLKK ++YK L++K+N +F+ +M ++C FQEIE HL QMK+F+S + L + + F++ ++VD LLE F+ +K TG P+ E
Sbjct: 2 TVDFNDYFWGEKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAHKAGTLNS-TFAPVWTILRTSAEKLSTLHLQMVQKLTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVAVQKLRDLYASKVQELEKLRK---DNGSH-KDAEKLESKLKKLQEEYKALLDKHNPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKPEMPELE 268 HSP 2 Score: 112.079 bits (279), Expect = 1.308e-24 Identity = 90/310 (29.03%), Postives = 150/310 (48.39%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRR---NEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLSTNQ-----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWE 3052
P L+I + IPLA+AF E ++A FR S + V SG +++SFP + N N A+ + F + L N+ +P K + QID S S ++ F + LRR N P + +FNVDI++Y V +P G+ + P + + W+ +S+ + ++++ N +AS + P V V +GS +QS P S W + R W D+S N +++++ L++GP TP + QF+ EG+ SG+ ++ G+ +R+S K R +SG+YV E
Sbjct: 857 PSPLTIGISDTIPLAVAFHEIIHAYFRGS-DESRCQVKVSGDMMLSFPAGIAGLLA----NNPNPAK-LGFRIKHVQNLENL--VPNGKLV--QIDRQQSSSVSTMLE-FNMGALTALLRRQAENNPTASYFNVDILKYQV--RTKP-GASSCPFQLVSYWKCE---SSYTALKVDYKYNNHAMASAS--------------PLLNVTLSVPVNGSVRNVQSKPHSAWLGESNRLVWNFTDISQNSQDGGVGTLRARLELNDGPSTPALLATQFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKYVCE 1135
BLAST of F-BAR domain only protein 2 vs. Ensembl Zebrafish
Match: fcho2 (FCH and mu domain containing endocytic adaptor 2 [Source:NCBI gene;Acc:553949]) HSP 1 Score: 177.178 bits (448), Expect = 3.779e-45 Identity = 103/294 (35.03%), Postives = 161/294 (54.76%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKEST 1021
M T F +NFWGDK+ GF VLY NMK G SS E DF+RE ++E++ ++S KL+K N + G+ P W K+ +EK + HMEL + +Q +IK VQKY+DEQ K TK+ T + + S L+++++ Y + LE ++ K G + D+++ K+KKA + YK +EKY T+F+ +M E+ FQ IE H+ +M++ I +S + + + E Q F +V++L+E +SK TGK P FE+ S I ++ K +K T
Sbjct: 1 MITPYFLENFWGDKNSGFYVLYHNMKHGQISSKELSDFIRERATIEEAYSRSMTKLAKTASNFSQLGTFAPVWDVFKQSTEKLAACHMELVRKLQELIKEVQKYVDEQAKNHKKTKEEVASTLEAVHNIQSVSQALLKSKENYINKTLEQERMRK----EGAKQGDLDKAGLKVKKATESYKSYVEKYATAKTEFEQRMTETAQKFQGIEEEHILRMQEIIHSYSLSVEETHIQIGEVQQEFVNNMENTSVESLIEKLAESKGTGKERPGPIEFEECNVS-IATEGAKPRKRKT 289 HSP 2 Score: 125.561 bits (314), Expect = 7.199e-29 Identity = 89/305 (29.18%), Postives = 159/305 (52.13%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL----DLSTNQSS--IKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P +++ S + +P+A+AFTE+VNA F+ + + V +G + +SFP +++ F S + + F L ASRL + +P + ++ ++ ++++ L L PA+ ++NVDI++Y V +N G + P+++ W+ + + L ++Y + N E +P PA P V+ LV +G MQSLP +IWN++ ++ W+L D S N+ S +++KF LS GP P + QF +EGS SGV +++ G+ +R+S +K R +GRY+
Sbjct: 550 PSPVTLASQDALPIAVAFTESVNAYFKGA-DPSKCIVKITGDMTLSFPSGIIKIFTSSPSPAV-----LSFKLLNASRLEQI--MPNQQLLHSDSSQSDTNTKDFWMNMPALTSFLRKSSEQNPAASYYNVDILKYQVCSN----GIQSTPLNLVVYWKCARS-TTDLRVDYRY---NPEA----MQP-PA--------PLTNVQVLVPVNGGVMNMQSLPNAIWNAEQNKSLWKLSDISDKSENEGSGSLRAKFELSEGPSIPATLAVQFFSEGSSLSGVDMELAGSGYRLSLNKKRFATGRYM 825
BLAST of F-BAR domain only protein 2 vs. Ensembl Zebrafish
Match: fcho2 (FCH and mu domain containing endocytic adaptor 2 [Source:NCBI gene;Acc:553949]) HSP 1 Score: 176.792 bits (447), Expect = 5.746e-45 Identity = 103/294 (35.03%), Postives = 161/294 (54.76%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKEST 1021
M T F +NFWGDK+ GF VLY NMK G SS E DF+RE ++E++ ++S KL+K N + G+ P W K+ +EK + HMEL + +Q +IK VQKY+DEQ K TK+ T + + S L+++++ Y + LE ++ K G + D+++ K+KKA + YK +EKY T+F+ +M E+ FQ IE H+ +M++ I +S + + + E Q F +V++L+E +SK TGK P FE+ S I ++ K +K T
Sbjct: 1 MITPYFLENFWGDKNSGFYVLYHNMKHGQISSKELSDFIRERATIEEAYSRSMTKLAKTASNFSQLGTFAPVWDVFKQSTEKLAACHMELVRKLQELIKEVQKYVDEQAKNHKKTKEEVASTLEAVHNIQSVSQALLKSKENYINKTLEQERMRK----EGAKQGDLDKAGLKVKKATESYKSYVEKYATAKTEFEQRMTETAQKFQGIEEEHILRMQEIIHSYSLSVEETHIQIGEVQQEFVNNMENTSVESLIEKLAESKGTGKERPGPIEFEECNVS-IATEGAKPRKRKT 289 HSP 2 Score: 125.561 bits (314), Expect = 8.713e-29 Identity = 89/305 (29.18%), Postives = 159/305 (52.13%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL----DLSTNQSS--IKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P +++ S + +P+A+AFTE+VNA F+ + + V +G + +SFP +++ F S + + F L ASRL + +P + ++ ++ ++++ L L PA+ ++NVDI++Y V +N G + P+++ W+ + + L ++Y + N E +P PA P V+ LV +G MQSLP +IWN++ ++ W+L D S N+ S +++KF LS GP P + QF +EGS SGV +++ G+ +R+S +K R +GRY+
Sbjct: 570 PSPVTLASQDALPIAVAFTESVNAYFKGA-DPSKCIVKITGDMTLSFPSGIIKIFTSSPSPAV-----LSFKLLNASRLEQI--MPNQQLLHSDSSQSDTNTKDFWMNMPALTSFLRKSSEQNPAASYYNVDILKYQVCSN----GIQSTPLNLVVYWKCARS-TTDLRVDYRY---NPEA----MQP-PA--------PLTNVQVLVPVNGGVMNMQSLPNAIWNAEQNKSLWKLSDISDKSENEGSGSLRAKFELSEGPSIPATLAVQFFSEGSSLSGVDMELAGSGYRLSLNKKRFATGRYM 845
BLAST of F-BAR domain only protein 2 vs. Ensembl Zebrafish
Match: fcho2 (pep chromosome:GRCz11:CHR_ALT_CTG5_1_30:35169667:35188100:-1 gene:ENSDARG00000112245.1 transcript:ENSDART00000165473.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:fcho2) HSP 1 Score: 149.443 bits (376), Expect = 1.902e-39 Identity = 90/259 (34.75%), Postives = 144/259 (55.60%), Query Frame = 2
Query: 173 WGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPP 946
+GDK+ GF VLY NMK G SS E DF+RE ++E++ ++S KL+K N + G+ P W K+ +EK + HMEL + +Q +IK VQKY+DEQ K TK+ T + + S L+++++ Y + LE ++ K G + D+++ K+KKA + YK +EKY T+F+ +M E+ FQ IE H+ +M++ I +S + + + E Q F +V++L+E +SK TGK P
Sbjct: 2 FGDKNSGFYVLYHNMKHGQISSKELSDFIRERATIEEAYSRSMTKLAKTASNFSQLGTFAPVWDVFKQSTEKLAACHMELVRKLQELIKEVQKYVDEQAKNHKKTKEEVASTLEAVHNIQSVSQALLKSKENYINKTLEQERMRK----EGAKQGDLDKAGLKVKKATESYKSYVEKYATAKTEFEQRMTETAQKFQGIEEEHILRMQEIIHSYSLSVEETHIQIGEVQQEFVNNMENTSVESLIEKLAESKGTGKERP 256
BLAST of F-BAR domain only protein 2 vs. Ensembl Zebrafish
Match: fcho1 (FCH and mu domain containing endocytic adaptor 1 [Source:NCBI gene;Acc:100913078]) HSP 1 Score: 156.377 bits (394), Expect = 3.205e-38 Identity = 91/278 (32.73%), Postives = 153/278 (55.04%), Query Frame = 2
Query: 176 GDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSS-GSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQT-QNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNK 1003
G+K+ GFDVLY NMK G ++ E +F+RE ++E++ +KS +KL+K + S G+ P W + S+K + H+EL + + +I+ + KY DEQ + TK+ + T +++ SL V L + R+ YH++ +E +L K G +++E+ E K KKA + + IEK+N F+ KM ES FQ+IE HL QMK I +S + + + F++ + ++ L++ F + K TGK P FE+ SS + S+++K
Sbjct: 13 GEKNAGFDVLYHNMKHGQIATKELAEFVRERAAIEETYSKSMSKLAKMASNGSPLGTFAPMWDVFRVSSDKLALCHLELMRKMNDLIRDINKYSDEQVKIHRKTKEEAIGTLESVQSLQVQNG-HLQKTREGYHSKCVELERLRK----EGVPQKELEKAELKCKKAAESFAGSIEKFNRAGGDFEQKMSESAQKFQDIEEAHLRQMKLLIKGYSHSIEDTHVQVGQVHEEFKQNVENIGIENLIQKFTEQKGTGKERPGPVGFEEYLSS-LASENSK 284 HSP 2 Score: 81.2629 bits (199), Expect = 4.555e-15 Identity = 82/315 (26.03%), Postives = 144/315 (45.71%), Query Frame = 2
Query: 2126 PSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPI-HFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLS-TNQS----SIKSKFMLSNGPGTPQP-VVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P+ + P +S+++ E P+A A TE +NA FR N V +G L +SFP + + F + N P+ F L SR+ + LP K + D+ + ++ L L P + ++NV +++Y ++ AP+ +SA Q + T+ T V SL + PA + +++ V+ L+ D S +Q PP+ WN++ R W+L +LS TN S ++ + + P P P + QF G+ SG+ +++ G+R+R+S K R +G+Y+
Sbjct: 856 PARGLSRGPSPISLSAQESWPVAAAITEYINAYFRGGEHNR-CLVKITGDLTMSFPAGITRIFTA------NPNAPVLSFRLVNISRVDHF--LPNQKLLYSDPSQSDPDTKDFWFNMQALTLHLQREAELNPQASYYNVALLKYQASSQ----DPSRAPLLLSAECQRSGTV--------------TRV-SLDYHCCPATAPATQLT---SVQVLLPLDHSATDLQCQPPAAWNAEERRLLWKLANLSPTNHSKGSGTLCASWQCLEVPRGPAPSLAVQFVGSGASLSGLDVELVGSRYRMSLVKKRFATGKYM 1139
BLAST of F-BAR domain only protein 2 vs. Ensembl Zebrafish
Match: fcho1 (FCH and mu domain containing endocytic adaptor 1 [Source:NCBI gene;Acc:100913078]) HSP 1 Score: 151.369 bits (381), Expect = 8.039e-37 Identity = 89/286 (31.12%), Postives = 154/286 (53.85%), Query Frame = 2
Query: 152 LTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQT-QNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNK 1003
+ F G+K+ GFDVLY NMK G ++ E +F+RE ++E++ +KS +KL+K N + G+ P W + S+K + H+EL + + +I+ + KY DEQ + TK+ + T +++ SL V L + R+ YH++ +E +L K G +++E+ E K KKA + + IEK+N F+ KM ES FQ+IE HL QMK I +S + + + F++ + ++ L++ F + K TGK P+ + + S + S+++K
Sbjct: 2 IHFFHTLQGEKNAGFDVLYHNMKHGQIATKELAEFVRERAAIEETYSKSMSKLAKMASNGSPLGTFAPMWDVFRVSSDKLALCHLELMRKMNDLIRDINKYSDEQVKIHRKTKEEAIGTLESVQSLQVQNG-HLQKTREGYHSKCVELERLRK----EGVPQKELEKAELKCKKAAESFAGSIEKFNRAGGDFEQKMSESAQKFQDIEEAHLRQMKLLIKGYSHSIEDTHVQVGQVHEEFKQNVENIGIENLIQKFTEQKGTGKERPEGPVGFEEYLSSLASENSK 282 HSP 2 Score: 84.3445 bits (207), Expect = 5.378e-16 Identity = 81/325 (24.92%), Postives = 147/325 (45.23%), Query Frame = 2
Query: 2087 SNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPI-HFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLD---LSTNQSSIKSKFMLSNGPGTPQP-VVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
S + S+ + P+ + P +S+++ E P+A A TE +NA FR N V +G L +SFP + + F + N P+ F L SR+ + LP K + D+ + ++ L L P + ++NV +++Y ++ P+ AP+ +SA Q + T+ T V SL + PA + +++ V+ L+ D S +Q PP+ WN++ R W+LD + ++ + + P P P + QF G+ SG+ +++ G+R+R+S K R +G+Y+
Sbjct: 602 STCVLYSKMLNCAPAG-LSRGPSPISLSAQESWPVAAAITEYINAYFRGGEHNRCL-VKITGDLTMSFPAGITRIFTA------NPNAPVLSFRLVNISRVDHF--LPNQKLLYSDPSQSDPDTKDFWFNMQALTLHLQREAELNPQASYYNVALLKYQASSQ-DPS---RAPLLLSAECQRSGTV--------------TRV-SLDYHCCPATAPATQLT---SVQVLLPLDHSATDLQCQPPAAWNAEERRLLWKLDDLSCVSGSGTLCASWQCLEVPRGPAPSLAVQFVGSGASLSGLDVELVGSRYRMSLVKKRFATGKYM 894
BLAST of F-BAR domain only protein 2 vs. Ensembl Xenopus
Match: fcho2 (FCH and mu domain containing endocytic adaptor 2 [Source:NCBI gene;Acc:100216087]) HSP 1 Score: 172.17 bits (435), Expect = 2.085e-43 Identity = 106/281 (37.72%), Postives = 158/281 (56.23%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQT----QNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDI 985
F DNFWG+K+ GFDVLY NMK G S+ E +F+RE ++E+ ++S NKL+K N G+ P W K +EK + H+EL + +Q +IK VQKY +EQ K TK+ T QNI S+ + L +A+D+Y+A+ LE KL K G +++IE+ K KKA + YK +EKY F+ KM E+ FQ+IE HL ++K+ I +S + +V + + F +TVD+LL+ F +SK TGK P FE+ ++ +
Sbjct: 6 FPDNFWGEKNSGFDVLYHNMKHGQISTKELSEFIRERSTIEEVYSRSMNKLAKSASNYTQLGTFGPVWDVFKTSTEKLAGCHLELVKKLQDLIKEVQKYGEEQLKSHKKTKEEVSGTLEAVQNIQSI----TQALHKAKDLYNAKCLEQEKLKK----EGAAAKEIEKAAIKTKKATESYKICVEKYAAAKLDFEQKMTETAQKFQDIEEAHLMRVKEIIESYSHSVSEVHIQIGQVHEDFINNMANITVDSLLQKFAESKGTGKERPGPIEFEECNTAVV 278 HSP 2 Score: 122.094 bits (305), Expect = 1.154e-27 Identity = 94/353 (26.63%), Postives = 178/353 (50.42%), Query Frame = 2
Query: 2033 PPLPAKITPPRSASTVPFSNSTIESRKFS-----SIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFC--LSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWE 3052
PPL + +PP SAS +P + S+ + + P+ I P +++ + + +P+A+A +E+VNA FR + T V +G++ +SFP +++ F S P C L SRL + LP ++ + ++ ++++ + L P++ ++NVDI++Y V +N G + P++++ W+ T + + + ++Y + N E ++ P+ N V+ LV DG MQSLP +IWN++ +A W++ + + +S S+++KF LS+GP P + QF ++G SGV +++ G +R+S K R +G+Y+ E
Sbjct: 491 PPLTSNTSPPPSAS-LPRAESSSSISSSASISAANTPTFGISRGPSPVTLGNQDTLPVAVALSESVNAYFRGA-DPTKCIVKITGEMTVSFPSGIIKVFTSN-------PSPAVLCFRLKNTSRLEQI--LPNNQLLYSDPSQSDNNCKDFWMNMQAVTAYLKKSSEQNPSASYYNVDILKYQVLSN----GIQSTPLNLATYWKCTSS-TTDVRLDYKY---NPESMAM-----PSILSN--------VQVLVPVDGGVTSMQSLPSAIWNAEQMKALWKVSVISEKSENGGAGSLRAKFDLSDGPSNPSTLAVQFVSDGCTLSGVDIELVGTGYRLSLVKKRFGTGKYMAE 811
BLAST of F-BAR domain only protein 2 vs. Ensembl Xenopus
Match: pak6 (p21 protein (Cdc42/Rac)-activated kinase 6 [Source:Xenbase;Acc:XB-GENE-960331]) HSP 1 Score: 167.548 bits (423), Expect = 8.830e-42 Identity = 92/270 (34.07%), Postives = 145/270 (53.70%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSS-GSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFE 964
F ++FWGDK+ GF VLY NMK G S E DF+RE ++E+S +KS KLSK ++ S G+ P W+ + S+K + H+ELS+ + +IK + +Y DEQ K +KD T LL S L ++RD Y +F E +L + G+ +++E+ E K +KA D + +EKYN +F+ KML+S +FQ+ E HL MK ++ +S + + + F+ + V+ L+ F +S TG P+ +E
Sbjct: 4 FGEHFWGDKNSGFAVLYHNMKHGQLSVKELADFVRERAAIEESYSKSMQKLSKMVSSGSHLGTFAPMWEMFRVSSDKLALCHLELSKKLHDLIKDISRYGDEQIKMHKKSKDEMSGTLEAIQLLQCNSQMLQKSRDNYCTKFSEQERLRR----EGSLQKELEKAELKTRKAADSLRCSVEKYNAVRKEFEQKMLQSAQTFQDTEATHLRHMKRLVTAYSHSVEDTHVQIGQVHEEFKHNMENVAVEKLIRRFAESNGTGTDRPEPVEYE 269 HSP 2 Score: 78.1814 bits (191), Expect = 5.029e-14 Identity = 82/329 (24.92%), Postives = 149/329 (45.29%), Query Frame = 2
Query: 2081 PFSNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFK-MQSLPPSIWNSDLGRASWRL--DLSTNQ----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
PFS S S PS I + S E +P+A AFTE V+A F E + + SG+L +SFP +L+ F S + + F L S + + P S+ + + +S ++++ L L + A+P++NV +++Y V + G AP+++++ W+ + ++ L ++Y +A L +V+ L+ D PF +QS PP+ R W++ + + N+ I +++ + P P V QF++EGS SGV +++ G+ +R+S K R +G+Y+
Sbjct: 623 PFSLGVGTSLGLSRGPSPVI--------LGSQESLPVAAAFTEYVHAVF-EGGALEGSSLRISGELTMSFPAGILRVFASTATPPV-----LSFRLIHTSHVEHFAP--NSELLFSDLSQSDPNSRDFWLNMPGLTSYLNNMAEQH-AAPYYNVTLLKYQVLKS----GISAAPLYLTSTWKCGPS-STDLCLDYR-----QNIAFLC-----------------DVQILLPLD-EPFSNLQSDPPARCAER--RLHWQIPHEPAGNEHDGWGRICARWQPLHAPSRPTSAVAQFTSEGSTLSGVDIELVGSGYRMSLVKKRFAAGKYL 904
BLAST of F-BAR domain only protein 2 vs. Ensembl Xenopus
Match: fcho2 (FCH and mu domain containing endocytic adaptor 2 [Source:NCBI gene;Acc:100216087]) HSP 1 Score: 155.992 bits (393), Expect = 2.168e-38 Identity = 100/274 (36.50%), Postives = 154/274 (56.20%), Query Frame = 2
Query: 176 GDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQT----QNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDI 985
G+K+ GFDVLY NMK G S+ E +F+RE ++E+ ++S NKL+K + N + + P W K +EK + H+EL + +Q +IK VQKY +EQ K TK+ T QNI S+ + L +A+D+Y+A+ LE KL K G +++IE+ K KKA + YK +EKY F+ KM E+ FQ+IE HL ++K+ I +S + +V + + F +TVD+LL+ F +SK TGK P FE+ ++ +
Sbjct: 3 GEKNSGFDVLYHNMKHGQISTKELSEFIRERSTIEEVYSRSMNKLAKSAS-NYTQTFGPVWDVFKTSTEKLAGCHLELVKKLQDLIKEVQKYGEEQLKSHKKTKEEVSGTLEAVQNIQSI----TQALHKAKDLYNAKCLEQEKLKK----EGAAAKEIEKAAIKTKKATESYKICVEKYAAAKLDFEQKMTETAQKFQDIEEAHLMRVKEIIESYSHSVSEVHIQIGQVHEDFINNMANITVDSLLQKFAESKGTGKERPGPIEFEECNTAVV 267 HSP 2 Score: 117.087 bits (292), Expect = 4.611e-26 Identity = 92/349 (26.36%), Postives = 175/349 (50.14%), Query Frame = 2
Query: 2033 PPLPAKITPPRSASTVPFSNSTIESRKFS-----SIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFC--LSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGR 3040
PPL + +PP SAS +P + S+ + + P+ I P +++ + + +P+A+A +E+VNA FR + T V +G++ +SFP +++ F S P C L SRL + LP ++ + ++ ++++ + L P++ ++NVDI++Y V +N G + P++++ W+ T + + + ++Y + N E ++ P+ N V+ LV DG MQSLP +IWN++ +A W++ + + +S S+++KF LS+GP P + QF ++G SGV +++ G +R+S K R +G+
Sbjct: 426 PPLTSNTSPPPSAS-LPRAESSSSISSSASISAANTPTFGISRGPSPVTLGNQDTLPVAVALSESVNAYFRGA-DPTKCIVKITGEMTVSFPSGIIKVFTSN-------PSPAVLCFRLKNTSRLEQI--LPNNQLLYSDPSQSDNNCKDFWMNMQAVTAYLKKSSEQNPSASYYNVDILKYQVLSN----GIQSTPLNLATYWKCTSS-TTDVRLDYKY---NPESMAM-----PSILSN--------VQVLVPVDGGVTSMQSLPSAIWNAEQMKALWKVSVISEKSENGGAGSLRAKFDLSDGPSNPSTLAVQFVSDGCTLSGVDIELVGTGYRLSLVKKRFGTGK 742
BLAST of F-BAR domain only protein 2 vs. Ensembl Xenopus
Match: fcho2 (FCH and mu domain containing endocytic adaptor 2 [Source:NCBI gene;Acc:100216087]) HSP 1 Score: 155.606 bits (392), Expect = 3.973e-38 Identity = 100/274 (36.50%), Postives = 154/274 (56.20%), Query Frame = 2
Query: 176 GDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQT----QNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDI 985
G+K+ GFDVLY NMK G S+ E +F+RE ++E+ ++S NKL+K + N + + P W K +EK + H+EL + +Q +IK VQKY +EQ K TK+ T QNI S+ + L +A+D+Y+A+ LE KL K G +++IE+ K KKA + YK +EKY F+ KM E+ FQ+IE HL ++K+ I +S + +V + + F +TVD+LL+ F +SK TGK P FE+ ++ +
Sbjct: 3 GEKNSGFDVLYHNMKHGQISTKELSEFIRERSTIEEVYSRSMNKLAKSAS-NYTQTFGPVWDVFKTSTEKLAGCHLELVKKLQDLIKEVQKYGEEQLKSHKKTKEEVSGTLEAVQNIQSI----TQALHKAKDLYNAKCLEQEKLKK----EGAAAKEIEKAAIKTKKATESYKICVEKYAAAKLDFEQKMTETAQKFQDIEEAHLMRVKEIIESYSHSVSEVHIQIGQVHEDFINNMANITVDSLLQKFAESKGTGKERPGPIEFEECNTAVV 267 HSP 2 Score: 117.472 bits (293), Expect = 4.167e-26 Identity = 91/347 (26.22%), Postives = 176/347 (50.72%), Query Frame = 2
Query: 2033 PPLPAKITPPRSASTVPFSNSTIESRKFS-----SIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGR 3040
PPL + +PP SAS +P + S+ + + P+ I P +++ + + +P+A+A +E+VNA FR + T V +G++ +SFP +++ F S + + F L SRL + LP ++ + ++ ++++ + L P++ ++NVDI++Y V +N G + P++++ W+ T + + + ++Y + N E ++ P+ N V+ LV DG MQSLP +IWN++ +A W++ + + +S S+++KF LS+GP P + QF ++G SGV +++ G +R+S K R +G+
Sbjct: 484 PPLTSNTSPPPSAS-LPRAESSSSISSSASISAANTPTFGISRGPSPVTLGNQDTLPVAVALSESVNAYFRGA-DPTKCIVKITGEMTVSFPSGIIKVFTSNPSPAV-----LCFRLKNTSRLEQI--LPNNQLLYSDPSQSDNNCKDFWMNMQAVTAYLKKSSEQNPSASYYNVDILKYQVLSN----GIQSTPLNLATYWKCTSS-TTDVRLDYKY---NPESMAM-----PSILSN--------VQVLVPVDGGVTSMQSLPSAIWNAEQMKALWKVSVISEKSENGGAGSLRAKFDLSDGPSNPSTLAVQFVSDGCTLSGVDIELVGTGYRLSLVKKRFGTGK 800
BLAST of F-BAR domain only protein 2 vs. Ensembl Xenopus
Match: fcho2 (FCH and mu domain containing endocytic adaptor 2 [Source:NCBI gene;Acc:100216087]) HSP 1 Score: 151.754 bits (382), Expect = 3.154e-37 Identity = 99/276 (35.87%), Postives = 152/276 (55.07%), Query Frame = 2
Query: 170 FWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQT----QNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDI 985
F+ GFDVLY NMK G S+ E +F+RE ++E+ ++S NKL+K + N + + P W K +EK + H+EL + +Q +IK VQKY +EQ K TK+ T QNI S+ + L +A+D+Y+A+ LE KL K G +++IE+ K KKA + YK +EKY F+ KM E+ FQ+IE HL ++K+ I +S + +V + + F +TVD+LL+ F +SK TGK P FE+ ++ +
Sbjct: 6 FYETHKHGFDVLYHNMKHGQISTKELSEFIRERSTIEEVYSRSMNKLAKSAS-NYTQTFGPVWDVFKTSTEKLAGCHLELVKKLQDLIKEVQKYGEEQLKSHKKTKEEVSGTLEAVQNIQSI----TQALHKAKDLYNAKCLEQEKLKK----EGAAAKEIEKAAIKTKKATESYKICVEKYAAAKLDFEQKMTETAQKFQDIEEAHLMRVKEIIESYSHSVSEVHIQIGQVHEDFINNMANITVDSLLQKFAESKGTGKERPGPIEFEECNTAVV 272 HSP 2 Score: 112.464 bits (280), Expect = 9.001e-25 Identity = 87/347 (25.07%), Postives = 169/347 (48.70%), Query Frame = 2
Query: 2042 PAKITPPRSASTVPFSNSTIESRKFSSIPSN------TIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFC--LSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGR 3040
PA+ T P S ++ + K ++ +I P +++ + + +P+A+A +E+VNA FR + T V +G++ +SFP +++ F S P C L SRL + LP ++ + ++ ++++ + L P++ ++NVDI++Y V +N G + P++++ W+ T + + + ++Y + N E ++ P+ N V+ LV DG MQSLP +IWN++ +A W++ + + +S S+++KF LS+GP P + QF ++G SGV +++ G +R+S K R +G+
Sbjct: 351 PARPTTPLSVGSIVPPPRPVSRPKLTAAKLCGINEVVSISRGPSPVTLGNQDTLPVAVALSESVNAYFRGA-DPTKCIVKITGEMTVSFPSGIIKVFTSN-------PSPAVLCFRLKNTSRLEQI--LPNNQLLYSDPSQSDNNCKDFWMNMQAVTAYLKKSSEQNPSASYYNVDILKYQVLSN----GIQSTPLNLATYWKCTSS-TTDVRLDYKY---NPESMAM-----PSILSN--------VQVLVPVDGGVTSMQSLPSAIWNAEQMKALWKVSVISEKSENGGAGSLRAKFDLSDGPSNPSTLAVQFVSDGCTLSGVDIELVGTGYRLSLVKKRFGTGK 666
BLAST of F-BAR domain only protein 2 vs. Ensembl Mouse
Match: Fcho2 (FCH domain only 2 [Source:MGI Symbol;Acc:MGI:3505790]) HSP 1 Score: 164.081 bits (414), Expect = 1.109e-44 Identity = 96/275 (34.91%), Postives = 150/275 (54.55%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + N + L ++++ Y A+ +E +L K G R+IE+ K KKA D YK +EKY T F+ KM E+ FQ+IE HL +K+ I S + ++ + + F T+++L++ F +SK TGK P FE+ + +
Sbjct: 6 FVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPMWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYTAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAVKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECDPA 276
BLAST of F-BAR domain only protein 2 vs. Ensembl Mouse
Match: Fcho2 (FCH domain only 2 [Source:MGI Symbol;Acc:MGI:3505790]) HSP 1 Score: 174.866 bits (442), Expect = 2.027e-44 Identity = 96/273 (35.16%), Postives = 149/273 (54.58%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAE 973
F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + N + L ++++ Y A+ +E +L K G R+IE+ K KKA D YK +EKY T F+ KM E+ FQ+IE HL +K+ I S + ++ + + F T+++L++ F +SK TGK P FE+ +
Sbjct: 6 FVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPMWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYTAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAVKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECD 274 HSP 2 Score: 126.716 bits (317), Expect = 3.646e-29 Identity = 92/316 (29.11%), Postives = 164/316 (51.90%), Query Frame = 2
Query: 2126 PSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDI---NIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P+ + P +S+ + + +P+AIA TE+VNA F+ + T V +G + ISFP +++ F S + + F + SRL + LP S+ + Q D+ T D ++++ + L L PA+ ++NVD+++Y V++N G + P++++ W+ + + + L ++Y + P VA P+ N ++ +V DG MQSLPP+IWN++ +A W+L + +S S+++KF LS GP P + QF +EG+ SGV +++ G +R+S K R +GRY+
Sbjct: 523 PTVGVSRGPSPVSLGNQDTLPVAIALTESVNAYFKGA-DPTKCIVKITGDVTISFPSGIIKVFTSNPSPAV-----LCFRVKNISRLEQI--LPNSQLVFSDPSQCDSNTKD---FWMNMQAVTIYLKKLSEQNPAASYYNVDVLKYQVSSN----GIQSTPLNLATYWKCSAS-TTDLRVDYKYN-PEAMVA-------PSVLSN--------IQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSGISEKSDSGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGNTLSGVDIELVGTGYRLSLVKKRFATGRYL 806
BLAST of F-BAR domain only protein 2 vs. Ensembl Mouse
Match: Fcho2 (FCH domain only 2 [Source:MGI Symbol;Acc:MGI:3505790]) HSP 1 Score: 166.777 bits (421), Expect = 2.661e-44 Identity = 96/275 (34.91%), Postives = 150/275 (54.55%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + N + L ++++ Y A+ +E +L K G R+IE+ K KKA D YK +EKY T F+ KM E+ FQ+IE HL +K+ I S + ++ + + F T+++L++ F +SK TGK P FE+ + +
Sbjct: 6 FVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPMWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYTAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAVKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECDPA 276
BLAST of F-BAR domain only protein 2 vs. Ensembl Mouse
Match: Fcho2 (FCH domain only 2 [Source:MGI Symbol;Acc:MGI:3505790]) HSP 1 Score: 166.777 bits (421), Expect = 2.999e-44 Identity = 96/275 (34.91%), Postives = 150/275 (54.55%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + N + L ++++ Y A+ +E +L K G R+IE+ K KKA D YK +EKY T F+ KM E+ FQ+IE HL +K+ I S + ++ + + F T+++L++ F +SK TGK P FE+ + +
Sbjct: 6 FVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPMWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYTAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAVKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECDPA 276
BLAST of F-BAR domain only protein 2 vs. Ensembl Mouse
Match: Fcho2 (FCH domain only 2 [Source:MGI Symbol;Acc:MGI:3505790]) HSP 1 Score: 166.777 bits (421), Expect = 3.761e-44 Identity = 96/275 (34.91%), Postives = 150/275 (54.55%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + N + L ++++ Y A+ +E +L K G R+IE+ K KKA D YK +EKY T F+ KM E+ FQ+IE HL +K+ I S + ++ + + F T+++L++ F +SK TGK P FE+ + +
Sbjct: 6 FVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPMWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYTAKCVEQERLKKE----GATQREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAVKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECDPA 276
BLAST of F-BAR domain only protein 2 vs. UniProt/SwissProt
Match: sp|D3ZYR1|FCHO2_RAT (F-BAR domain only protein 2 OS=Rattus norvegicus OX=10116 GN=Fcho2 PE=1 SV=1) HSP 1 Score: 175.637 bits (444), Expect = 8.600e-44 Identity = 96/273 (35.16%), Postives = 150/273 (54.95%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAE 973
F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + N + L ++++ Y+A+ +E +L K G R+IE+ K KKA D YK +EKY T F+ KM E+ FQ+IE HL +K+ I S + ++ + + F T+++L++ F +SK TGK P FE+ +
Sbjct: 6 FVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYNAKCVEQERLKK----EGATPREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECD 274 HSP 2 Score: 126.716 bits (317), Expect = 2.400e-28 Identity = 92/316 (29.11%), Postives = 164/316 (51.90%), Query Frame = 2
Query: 2126 PSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDI---NIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P+ + P +S+ + + +P+AIA TE+VNA F+ + T V +G + ISFP +++ F S + + F + SRL + LP S+ + Q D+ T D ++++ + L L PA+ ++NVD+++Y V++N G + P++++ W+ + + + L ++Y + P VA P+ N ++ +V DG MQSLPP+IWN++ +A W+L + +S S+++KF LS GP P + QF +EG+ SGV +++ G +R+S K R +GRY+
Sbjct: 523 PTVGVSRGPSPVSLGNQDTLPVAIALTESVNAYFKGA-DPTKCIVKITGDVTISFPSGIIKVFTSNPSPAV-----LCFRVKNISRLEQI--LPNSQLVFSDPSQCDSNTKD---FWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSN----GIQSTPLNLATYWKCSAS-TTDLRVDYKYN-PEAMVA-------PSVLSN--------IQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSGISEKSDSGGSGSLRAKFDLSEGPSKPATLAVQFLSEGNTLSGVDIELVGTGYRLSLVKKRFATGRYL 806
BLAST of F-BAR domain only protein 2 vs. UniProt/SwissProt
Match: sp|Q3UQN2|FCHO2_MOUSE (F-BAR domain only protein 2 OS=Mus musculus OX=10090 GN=Fcho2 PE=1 SV=1) HSP 1 Score: 174.866 bits (442), Expect = 1.418e-43 Identity = 96/273 (35.16%), Postives = 149/273 (54.58%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAE 973
F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + N + L ++++ Y A+ +E +L K G R+IE+ K KKA D YK +EKY T F+ KM E+ FQ+IE HL +K+ I S + ++ + + F T+++L++ F +SK TGK P FE+ +
Sbjct: 6 FVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPMWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYTAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAVKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECD 274 HSP 2 Score: 126.716 bits (317), Expect = 2.551e-28 Identity = 92/316 (29.11%), Postives = 164/316 (51.90%), Query Frame = 2
Query: 2126 PSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDI---NIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P+ + P +S+ + + +P+AIA TE+VNA F+ + T V +G + ISFP +++ F S + + F + SRL + LP S+ + Q D+ T D ++++ + L L PA+ ++NVD+++Y V++N G + P++++ W+ + + + L ++Y + P VA P+ N ++ +V DG MQSLPP+IWN++ +A W+L + +S S+++KF LS GP P + QF +EG+ SGV +++ G +R+S K R +GRY+
Sbjct: 523 PTVGVSRGPSPVSLGNQDTLPVAIALTESVNAYFKGA-DPTKCIVKITGDVTISFPSGIIKVFTSNPSPAV-----LCFRVKNISRLEQI--LPNSQLVFSDPSQCDSNTKD---FWMNMQAVTIYLKKLSEQNPAASYYNVDVLKYQVSSN----GIQSTPLNLATYWKCSAS-TTDLRVDYKYN-PEAMVA-------PSVLSN--------IQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSGISEKSDSGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGNTLSGVDIELVGTGYRLSLVKKRFATGRYL 806
BLAST of F-BAR domain only protein 2 vs. UniProt/SwissProt
Match: sp|Q5R807|FCHO2_PONAB (F-BAR domain only protein 2 OS=Pongo abelii OX=9601 GN=FCHO2 PE=2 SV=1) HSP 1 Score: 174.481 bits (441), Expect = 1.603e-43 Identity = 97/280 (34.64%), Postives = 153/280 (54.64%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
M F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + +T+ L ++++ Y+A+ +E +L K G R+IE+ K KKA D YK +EKY F+ KM E+ FQ+IE HL +K+ I S + ++ + + F TV++L++ F +SK TGK P FE+ +++
Sbjct: 1 MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSTTQALQKSKENYNAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEVIGSLSNAIKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTA 276 HSP 2 Score: 126.716 bits (317), Expect = 2.304e-28 Identity = 90/316 (28.48%), Postives = 163/316 (51.58%), Query Frame = 2
Query: 2126 PSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDI---NIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P+ + P +S+ + + +P+A+A TE+VNA F+ + T V +G + +SFP +++ F S + + F + SRL + LP ++ + Q D+ T D ++++ + L L PA+ ++NVD+++Y V++N G + P++++ W+ + + + L ++Y + P VA P+ N ++ +V DG MQSLPP+IWN++ +A W+L + +S S+++KF LS GP P + QF +EGS SGV ++ G +R+S K R +GRY+
Sbjct: 524 PTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGA-DPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAV-----LCFRVKNISRLEQI--LPNAQLVFSDPSQCDSNTKD---FWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSN----GIQSTPLNLATYWKCSAS-TTDLRVDYKYN-PEAMVA-------PSVLSN--------IQVVVPVDGGVMNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYL 807
BLAST of F-BAR domain only protein 2 vs. UniProt/SwissProt
Match: sp|Q502I9|FCHO2_DANRE (F-BAR domain only protein 2 OS=Danio rerio OX=7955 GN=fcho2 PE=2 SV=1) HSP 1 Score: 173.711 bits (439), Expect = 3.924e-43 Identity = 101/294 (34.35%), Postives = 161/294 (54.76%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKEST 1021
M T F +NFWG+K+ GF VLY NMK G SS E DF+RE ++E++ ++S KL+K N + G+ P W K+ +EK + HMEL + +Q +IK VQKY+DEQ K TK+ T + + S L+++++ Y + LE ++ K G + D+++ K+KKA + YK +EKY T+F+ +M E+ FQ IE H+ +M++ I +S + + + E Q F +V++L+E +S+ TGK P FE+ S I ++ K +K T
Sbjct: 1 MITPYFLENFWGNKNSGFYVLYHNMKHGQISSKELSDFIRERATIEEAYSRSMTKLAKTASNFSQLGTFAPVWDVFKQSTEKLAACHMELVRKLQELIKEVQKYVDEQAKNHKKTKEEVASTLEAVHNIQSVSQALLKSKENYINKTLEQERMRK----EGAKQGDLDKAGLKVKKATESYKSYVEKYATAKTEFEQRMTETAQKFQGIEEEHILRMQEIIHSYSLSVEETHIQIGEVQQEFVNNMENTSVESLIEKLAESRGTGKERPGPIEFEECNVS-IATEGAKPRKRKT 289 HSP 2 Score: 125.561 bits (314), Expect = 5.581e-28 Identity = 89/305 (29.18%), Postives = 160/305 (52.46%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL----DLSTNQSS--IKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P +++ S + +P+A+AFTE+VNA F+ + + V +G + +SFP +++ F S + + F L ASRL + +P + ++ ++ ++++ L L PA+ ++NVDI++Y V +N G + P+++ W+ + + + L ++Y + N E +P PA P V+ LV +G MQSLP +IWN++ ++ W+L D S N+ S +++KF LS GP P + QF +EGS SGV +++ G+ +R+S +K R +GRY+
Sbjct: 570 PSPVTLASQDALPIAVAFTESVNAYFKGA-DPSKCIVKITGDMTLSFPSGIIKIFTSSPSPAV-----LSFKLLNASRLEQI--MPNQQLLHSDSSQSDTNTKDFWMNMPALTSFLRKSSEQNPAASYYNVDILKYQVCSN----GIQSTPLNLVVYWKCSRS-TTDLRVDYRY---NPEA----MQP-PA--------PLTNVQVLVPVNGGVMNMQSLPNAIWNAEQNKSLWKLSDISDKSENEGSGSLRAKFELSEGPSIPATLAVQFFSEGSSLSGVDMELAGSGYRLSLNKKRFATGRYM 845
BLAST of F-BAR domain only protein 2 vs. UniProt/SwissProt
Match: sp|Q0JRZ9|FCHO2_HUMAN (F-BAR domain only protein 2 OS=Homo sapiens OX=9606 GN=FCHO2 PE=1 SV=2) HSP 1 Score: 172.94 bits (437), Expect = 5.539e-43 Identity = 96/280 (34.29%), Postives = 152/280 (54.29%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
M F +NFWG+K+ GFDVLY NMK G S+ E DF+RE ++E++ ++S KL+K N + G+ P W K +EK + H++L + +Q +IK VQKY +EQ K TK+ T + + + L ++++ Y+A+ +E +L K G R+IE+ K KKA D YK +EKY F+ KM E+ FQ+IE HL +K+ I S + ++ + + F TV++L++ F +SK TGK P FE+ +++
Sbjct: 1 MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKK----EGATQREIEKAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTA 276 HSP 2 Score: 125.946 bits (315), Expect = 4.732e-28 Identity = 90/316 (28.48%), Postives = 163/316 (51.58%), Query Frame = 2
Query: 2126 PSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDI---NIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P+ + P +S+ + + +P+A+A TE+VNA F+ + T V +G + +SFP +++ F S + + F + SRL + LP ++ + Q D+ T D ++++ + L L PA+ ++NVD+++Y V++N G + P++++ W+ + + + L ++Y + P VA P+ N ++ +V DG MQSLPP+IWN++ +A W+L + +S S+++KF LS GP P + QF +EGS SGV ++ G +R+S K R +GRY+
Sbjct: 524 PTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGA-DPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAV-----LCFRVKNISRLEQI--LPNAQLVFSDPSQCDSNTKD---FWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSN----GIQSTPLNLATYWKCSAS-TTDLRVDYKYN-PEAMVA-------PSVLSN--------IQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYL 807
BLAST of F-BAR domain only protein 2 vs. TrEMBL
Match: A0A224Z5G6 (Proline serine threonine phosphatase interacting protein pstpip OS=Rhipicephalus zambeziensis OX=60191 PE=4 SV=1) HSP 1 Score: 281.567 bits (719), Expect = 1.770e-76 Identity = 269/1002 (26.85%), Postives = 445/1002 (44.41%), Query Frame = 2
Query: 149 TLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTD----PSLNGNHIGDVITGNLVNXXXXXXXXXTHVSNVNITTPNAKDSINDIFDQLS-NISDNNSINQTTVSHIDGGTVSIPIKKQKKYNNIFRRKRNSPSNGVTQKQLQDTDKEKSSQSLGEYMVDDEGYTIKP-NDPWPXXXXXXXXXXXXXXXXXXXIFKAIKIEIKPKDNKSDSSSIPDNDLPIKAKSKNNDNLELFKAVQAFKISPNIFRDGNRRTGDSRSNTP-SLPNVLA-----DDGSPPTSTRLNSISVSIRD-SRRKKNSRSQSEQAQSLAQPYFQVEFTNSFESNGLDLAGVTSDPFNSRFESFQSSKADLPLKTNENKIDPWGSSTVNDKSIQPPPLPAKITPPRSASTVPFSNSTIESRKFSSIPSNTIPA----TPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNF-----QWPNTEVASLTFRPS---PAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLD-------LSTNQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEP 3055
T+ F D FWG+K+ GFDVLY NMK G ++ + +F RE +E+S +K +KL++Q S+G+ P W ++ SEK S+ H ++ +Q +++ VQ+Y +EQ + K K+ + T + L T+ L +AR+ Y AR LE KL + + +D+++ EAK +KA ++Y+ L+E++ F+ +M SC FQE+E HL+ MK+F++ ++ L + F + L +D LL F ++ TG P+ FE+ + S + N S T PS +G+ G V+ + +++ S+ +N P A + + F + + +S D T S + D ++S + E VD+EGYT++P ++ +++++S SS D + ++ + I IEIKP N + S+ D EL + + +SP I + RR +S S+TP P A D + T + + + D S +R QS Q +P Q + S S D SD FN + + SS T P +S ++ PP AS +P S + S + +P P L+I + IPLA+AF E V+A+FR + T V G + +SFP ++ V N + A + F ++ A R NV LP I + T D ++ L L P++ +FN+DI++Y V G+ +AP+H+ A W+ T + L I+Y + P A+ +P+ PA S + P + V DG +Q+ PP IWN + RA WRL S+ ++F L+ GP TP+P+ +F EG+ SG ++ G +R+S K +++SG+Y+ EP
Sbjct: 2 TVDFRDYFWGEKNNGFDVLYHNMKYGYLAAKDLAEFFRERSLVEESHSKLLSKLARQAAGSCSTGTFGPLWGVLRSTSEKLSSLHAQMVAQLQDLVREVQRYCEEQHRRHKQVKEEEAPTLEVVQGLQQTTGALAKAREAYAARCLELEKLKRE-----SSPKDLDKAEAKARKACEEYRQLVERHGVVRADFERRMAGSCQRFQELEVGHLQHMKEFLAGYARVLDSSHALVGQVHAEFRQQCDALDIDALLRQFASARQTGSEKPEAITFEEPDPSLQLTPTNAASTGSPPFFTTSTPAPSASGSENGPVLPADFCPASAAAAAPSSAATN----GPQAPAAKKEGFLRTKWERQKEKRKRKKEMSSKDASTTS-----------------------------GEADSKESEEQNAE--VDEEGYTVRPSSERHKENDRDSFYSSSDGDSDDEDRDRRIHIEIKPLSNGAPMSASVD---------------ELRATIGSLSLSP-IPQHSARRAYNSASSTPDEAPKRPANQSSKDSAGIGSGTEADMLGLFPLDTSASTPTTRLQSPLGQ--GEPASQPSASGSVPS--WDRYAALSDLFNDKAPAESSSSEASKGATTSRGGTP--TSAFTGPALPRPPSRRSEAVRGRASPLPMSRTESVGSLSSDFKTTPMPLGSSRGPSPLTIGLCDSIPLAVAFQEVVHARFRGT-DETLCQVKLLGDMKVSFPAGIVH----VLTNNPSPAA-LTFRVNTA-RFDNV--LPNKNLITLDASQSTSDRCVYEFNMSVLTGLLRRQHEQTPSASYFNIDILKYHVRAG---PGARSAPLHLVAFWK-TQEDNTDLKIDYEYNAKALSLPAGTGATGVGQPASSNPAPSAPG-LPPLTGLCLGVPMDGGVTSVQAKPPCIWNGETQRALWRLSDPLGGTAGGQRGGSLLARFALTRGPSTPRPLEARFLCEGATLSGASFELIGQGYRVSLVKRQILSGKYLCEP 927
BLAST of F-BAR domain only protein 2 vs. TrEMBL
Match: A0A183AXU1 (F-BAR domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS11776 PE=4 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 4.693e-62 Identity = 118/288 (40.97%), Postives = 181/288 (62.85%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINV---NSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQD 997
ME F+ NFWG+K+ GFDVLYQN+K +S+SEF +F+R+ S+ED+ KS KL+KQ NS S +P W +++L E+ H+ +Q+ Q + K VQKY++EQQ + KS +D + TQ + T+ QL RA++VYH+R+ E+ + +S+ ++ +R+ E+MEAKLKKA D+YKY +EKYNN +F SKM SC FQE+E HLEQM++F+ R+S+ + ++ F + ++T LL+MF+ + TG P+ FEDAE + + S +
Sbjct: 1 MEPCLFARNFWGEKNTGFDVLYQNLKLSYRSTSEFAEFVRDSSSIEDAYYKSLLKLAKQTGSYSNNSVSSFKPCWSILRQLVEQLGQLHLVFAQSRQSLSKDVQKYLEEQQKRHKSIRDAEASTQEVVHAFQVTAVQLHRAKEVYHSRYAEYERTMRSESSS---TREQEKMEAKLKKAQDEYKYSVEKYNNLRNQFVSKMAASCAQFQEVEVAHLEQMREFMQRYSSVWSAARDTMDKLCAQFNQDLTQMTTARLLDMFVAERGTGTTEPRIVPFEDAEVAAVFSAN 285
BLAST of F-BAR domain only protein 2 vs. TrEMBL
Match: A0A4E0S0B5 (FCH domain only protein 2 OS=Fasciola hepatica OX=6192 GN=D915_003796 PE=4 SV=1) HSP 1 Score: 238.81 bits (608), Expect = 5.520e-61 Identity = 119/284 (41.90%), Postives = 182/284 (64.08%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINV---NSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDI 985
ME F++NFWG+K+ GFDVLYQN+K+ +S+S+F +F+RE S+ED+ KS KL+KQ N+ S +P W +++L E+ H+ SQ+ Q + K VQKY++EQQ + KS +D + TQ + T+ QL RA++VYH+R+ E+ + +S+ ++ +R+ E++EAKLKKA D+YKY +EKYNN +F SKM SC FQEIE HLEQM++F+ R+S+ + ++ F++ K+T LLEMF+ + TG P+ FEDAE + +
Sbjct: 1 MERCLFAENFWGEKNTGFDVLYQNLKSSCRSTSDFAEFVRESSSIEDAYYKSLLKLAKQTASYSNNNVSSFKPCWSVLRQLVEQLGQLHLAFSQSRQSLSKDVQKYLEEQQKRHKSIRDAETSTQEVVHAFQVTAVQLHRAKEVYHSRYAEYERTVRSESSS---TREQEKVEAKLKKAQDEYKYSVEKYNNLRNQFVSKMSASCAQFQEIEVAHLEQMREFMQRYSSVWSTTRETMDKLCAQFDEDLTKMTTMKLLEMFVAERGTGSTQPRIVPFEDAEVAAV 281 HSP 2 Score: 114.39 bits (285), Expect = 7.753e-22 Identity = 105/387 (27.13%), Postives = 173/387 (44.70%), Query Frame = 2
Query: 2090 NSTIESRKFSSI---PSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFR----ESFSN----TPHDVHT-SGQLVISFPCSMLQQF---ESVGENQLNLAEPIHFCLSQASRLRNVE-----------PLPTSKD---------INIQIDNPTDDSYSIYIDLF--TLHKKLTTLR-RNEPASPFFNVDIIRYDV----TNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWP-NTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTN---------------QSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEPSTNTTGF 3076
NST+ FSS P N +P N I +A AFTET A+F SFS TP + SG+L ++FP + ++Q +VG P+ L+ A RL++++ PL ++ ++ + P ++DL T K T + N A + +DI+ Y V ++ P ++ P+H+ W+ T+ + ++Y +WP + ++ S T R G++R ++ DG +MQSLP W +L RA+W++ L+ + ++++KF L +GPG PQPV QF E + SGV L + +R+S K R+I RYV +P ++T F
Sbjct: 788 NSTMSIPSFSSGTVGPWNQVP-------TNQAGSISVAAAFTETWRARFHNGGGSSFSTAAMITPPPIQAVSGELTLAFPRTSVEQMVTHSAVG--------PLVLRLNNAVRLKDLQLRVVGSSMVGCPLESAAPMSSPSSGVTMDFVLTVPGSVLMERFVDLLAETASSKTGTGKTSNNQAMSYLKMDILSYTVDVCQGSDCAPYPALTPPIHLCTYWRCDQTV-TDFRLDYATRWPSDKQITSRTSR--------------GDLRVILNVDGGVTRMQSLPMGTWMPELSRATWQIPLTPSTDALGVNSRETSIDTSGTVRAKFTLDHGPGRPQPVALQFFREDCLASGVQLILDCPMYRLSLCKRRVIGDRYVCDPPNHSTRF 1144
BLAST of F-BAR domain only protein 2 vs. TrEMBL
Match: A0A5J4NMJ2 (F-BAR domain only protein OS=Paragonimus westermani OX=34504 GN=DEA37_0010067 PE=4 SV=1) HSP 1 Score: 234.572 bits (597), Expect = 1.546e-59 Identity = 112/287 (39.02%), Postives = 183/287 (63.76%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQIN-VNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDN 1000
M++ F+ +FWGDKH GFDVLYQN+K +S+++F +FLRE +S++D+ K+ +KL+KQ N + + +P W +++ E+ H +Q+ Q ++K VQKY++EQQ + KS K+ ++ TQ + T+ QL +A+++Y R E+ ++ + N + +RD E++EAKLKK+ D+YKYLIEKYNN +F KM SC FQEIE HL+QM++F+ R+S+ F + ++ FE+ +++ + LL++F+K + TG P+ FEDAE + S N
Sbjct: 1 MDSCLFAQHFWGDKHMGFDVLYQNLKLACRSTNDFAEFLRESFSVDDAYCKAISKLAKQAGSYNIASTFKPCWSIVRQFIEQIGQLHSNFTQDRQALLKDVQKYIEEQQKRYKSVKEGEVSTQEVVHAFQVTTVQLQKAKELYFCRHTEYQRMLR---NESSSTRDQEKLEAKLKKSQDEYKYLIEKYNNLRNQFVGKMQTSCAQFQEIEVSHLDQMREFLHRYSSAWFTGRQGLDKLLLQFEEYFAQMSTEQLLQLFVKERGTGSTIPQGIAFEDAEVAAAFSTPN 284 HSP 2 Score: 112.079 bits (279), Expect = 4.428e-21 Identity = 100/371 (26.95%), Postives = 153/371 (41.24%), Query Frame = 2
Query: 2120 SIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFR----ESFSNT-----PHDVHTSGQLVISFPCSMLQQF---ESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDN-------------------PTDDSYSIYIDLFTLHKK----LTTLRRNEPASP------FFNVDIIRYDVTNNVRPN-GSINAPVHISANWQITDTLASHLMINYNFQWP-NTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL----------------DLSTNQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEP 3055
++P +PA P IP+A AFTET +F SFS P SG L ++FP ++Q SVG L L I F K+I +++D P+ D Y I I L + L+T R+ S + +D++ Y V N N ++ P+H+ W+ + A+ ++Y WP N + S + R G++R + DG +MQSLP +W D+ RA+W++ L+ ++++KF L NGPG PQPV QF E + SGV L V G +++S K R+I RY+ +P
Sbjct: 845 TLPRTLLPAKP----------IPIAAAFTETWRVRFHNGGGSSFSTAASIIPPPLQAVSGTLTLAFPTLAVEQLVREPSVGPLVLRLNNAIRF-----------------KNIQLKLDGSFISDCSSDSTSTCGASTYPSAD-YVITIPGTALVQHFTNILSTFSRSAADSSGANISNYVKLDVLSYAVELNAIMNLQALTPPIHLCTYWRC-ERGATDFRLDYTSHWPSNDQAVSRSIR--------------GDLRISLNVDGGVSRMQSLPMGVWLPDVHRATWQIPFSQPLDNVSSRAASDSLTVCSGTVRAKFTLVNGPGRPQPVALQFVREDCLASGVRLAVEGLEYKLSLCKQRIIGDRYICDP 1172
BLAST of F-BAR domain only protein 2 vs. TrEMBL
Match: A0A183WKJ9 (F-BAR domain-containing protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS12651 PE=4 SV=1) HSP 1 Score: 214.542 bits (545), Expect = 1.330e-58 Identity = 112/278 (40.29%), Postives = 170/278 (61.15%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQIN-VNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAE 973
M FS +FWG+KH GFD +YQN K ++S+EF +FLRE YS ED+ K+ KLSKQ N++ S +P W +K+L ++ S H+ ++Q Q + + VQKY++EQ +QK KD + TQ + TS QL +A++ YH+R+ E+ + + + + SR+ E++E KLKKA D+YKY +EKYNN +F SKM SC F+EIE HLEQM++F+ R+++ + F++ +LT D LL + + + TG + P+ FEDAE
Sbjct: 1 MSACLFSQHFWGEKHSGFDAMYQNFKLCYRTSAEFAEFLRESYSAEDNYYKALIKLSKQAGSYNNTSSFKPCWSLLKQLIDQVSQVHLNIAQERQNLSRDVQKYLEEQHKRQKLIKDTEASTQEVVHAFQVTSMQLQKAKEAYHSRYSEYERAMRLESGS---SREQEKLEVKLKKAQDEYKYSVEKYNNLRNQFVSKMHISCAQFEEIEVAHLEQMREFLHRYASVWSVTGDALGKLHNQFDQDLAELTTDRLLNILVSERGTGTLEPQGVQFEDAE 275
BLAST of F-BAR domain only protein 2 vs. Ensembl Cavefish
Match: fcho1 (FCH and mu domain containing endocytic adaptor 1 [Source:NCBI gene;Acc:100913078]) HSP 1 Score: 159.073 bits (401), Expect = 2.226e-39 Identity = 91/290 (31.38%), Postives = 154/290 (53.10%), Query Frame = 2
Query: 170 FWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTD 1036
F G+K+ GFDVLY NMK G ++ E +F+RE ++E++ +KS +KL+K N ++ G+ P W + S+K + H+EL + + +I+ + KY DEQ + TK+ + T L + L ++R+ YHA+ E +L K G +++E+ E K KKA + + IEK+N F+ KM ES FQ+IE HL QMK I +S + + + F++ + + +L++ F + K TGK P FE+ SS + + K + +++ + D
Sbjct: 22 FQGEKNAGFDVLYHNMKHGQIATKELAEFVRERAAVEETYSKSMSKLAKMASNGSTLGTFAPMWDVFRVSSDKLALCHLELMRKMNDLIRDINKYGDEQAKVHRKTKEEVMGTLEAVQTLQVQNGHLQKSREGYHAKCTELERLRK----EGAPQKELEKAELKSKKAAESFASSIEKFNRAGGDFEQKMSESAQKFQDIEEAHLRQMKQLIKGYSHSIEDTHVQVGQVHEEFKQNVENIGIGSLIQKFTEQKGTGKDRPVPVGFEEYLSSQLPDNNKKSRAKNSPLEVD 307 HSP 2 Score: 81.2629 bits (199), Expect = 3.662e-15 Identity = 83/305 (27.21%), Postives = 140/305 (45.90%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPI-HFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLS-TNQSS---IKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P +S+++ E P+A A TE +NA F+ N V +G L +SFP + + F + N P+ F L SR+ + LP K + DS + ++ L L P + ++NV +++Y V++ AP+ +SA Q + T+ T V SL + PA + +++ V+ L+ D + +Q PP+ WN++ R W+L +LS TN SS S L G P + QF G+ SG+ +++ G+R+R+S K R +G+Y+
Sbjct: 566 PSPISLSTQEAWPVAAAITEYINAYFKGGEHNRCL-VKITGDLTMSFPAGITRLFTA------NPNAPVLSFRLVNISRVDHF--LPNQKLLFSDPSQNDPDSRDFWFNMQALTFHLQREAELNPQASYYNVGLLKYQVSSQ----DPARAPLLLSAECQRSGTV--------------TRV-SLDYHCCPATAPATQLT---AVQVLLPLDHTATDLQCQPPASWNAEERRLLWKLPNLSPTNHSSGTLCASWQCLEVPRGPPPSLAVQFVGSGASLSGMDVELVGSRYRMSLVKKRFATGKYM 839
BLAST of F-BAR domain only protein 2 vs. Ensembl Cavefish
Match: fcho2 (FCH and mu domain containing endocytic adaptor 2 [Source:NCBI gene;Acc:553949]) HSP 1 Score: 125.946 bits (315), Expect = 4.130e-29 Identity = 87/308 (28.25%), Postives = 155/308 (50.32%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHG---EVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLST-----NQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P +++ S + +P+A+AFTE+VNA F+ + + V +G + +SFP +++ F S + + F L S+L + LP ++ D+ ++++ L L P S ++NVD+++Y V +N G + P++++ W+ T + L ++Y + N E ++PHG V+ LV +G MQS+P +IWN+D ++ W+L D+S S+++KF LS+GP P + QF EGS SG +++ G+ +R+S +K R SGRY+
Sbjct: 503 PSPVTLASQDALPIAVAFTESVNAYFKGA-DPSKCIVKITGDMTLSFPSGIIKIFTSSPSPAV-----LSFKLKNTSKLEQI--LPNQHLLHSDSSQSDTDTRDFWLNMPALTAYLRKNSEQNPTSSYYNVDVLKYQVCSN----GIQSTPLNLAVYWKCGPT-TTDLRVDYRY---NPEA----------------MQPHGPLSSVQVLVPVNGGVTNMQSIPNAIWNADQNKSLWKLNDISEKSENEGSGSLRAKFELSDGPSIPATLAVQFFNEGSTLSGADMELVGSGYRLSLNKKRFASGRYM 778 HSP 2 Score: 124.02 bits (310), Expect = 1.643e-28 Identity = 75/228 (32.89%), Postives = 120/228 (52.63%), Query Frame = 2
Query: 341 SLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQT----QNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQK 1012
+ P W K +EK ++ HMEL + +Q +IK VQKY+DEQ K TK+ T QNI S+ S L ++++ Y+++ LE ++ K G RD+++ K+KKA + YK +EKY T T+F+ KM E+ FQ+IE H+ MK+ I +S + + E F +V++L++ +SK TGK P FE+ S + ++ K +K
Sbjct: 37 TFAPIWDVFKVSTEKLASCHMELVRKLQELIKEVQKYVDEQAKAHKKTKEEVASTLEAVQNIQSV----SQALQKSKENYNSKTLEQERMRK----EGATQRDLDKTGVKVKKATEVYKSFVEKYATTKTEFEQKMAETAQKFQDIEESHILHMKEIIQSYSCSVEDTHKQIEEVHQEFVNNMENTSVESLIQKLAESKGTGKERPGPIEFEECNVSTVATEAAKPRK 256
BLAST of F-BAR domain only protein 2 vs. Ensembl Cavefish
Match: sgip1a (SH3GL interacting endocytic adaptor 1a [Source:ZFIN;Acc:ZDB-GENE-131121-25]) HSP 1 Score: 119.013 bits (297), Expect = 2.638e-27 Identity = 86/310 (27.74%), Postives = 158/310 (50.97%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEP--IHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHG--EVRFLVIADGSPFKMQS-LPPSIWNSDLGRASWRL-DLSTNQ-----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P L++ + + +P+A AFTETVN+ F+ + + V +G++V+SFP + + F N P + F ++ S L +V P P + NP +S ++++ L L + +P + ++NVD+++Y V+ G + P++++ NW+ T ++ L I+Y + +GN+ P V+FL+ DG K+Q+ LPP+ WN++ R W++ D+S S+ ++F L++GP P P+ QF++EGS SG +++ G +R S K R +G+Y+
Sbjct: 302 PSPLTMGAQDTLPVAAAFTETVNSYFKGT-DPSKCVVKITGEMVLSFPAGITRHFA-------NNPSPAVLTFSITNYSCLEHVLPNPQLLCCDTTQSNP--NSKEFWVNMTNLMAHLKKVAEQKPQATYYNVDMLKYQVS----AQGPQSTPLNLAVNWRCEPT-STDLRIDYKY------------------NGNAMTTPVALNNVQFLIPVDGGVNKLQAVLPPAAWNAEQQRILWKIPDISQKSENGGVGSLLARFQLTDGPSKPAPLAVQFTSEGSTLSGCDIELVGPGYRFSLIKKRFAAGKYM 578
BLAST of F-BAR domain only protein 2 vs. Ensembl Cavefish
Match: sgip1b (SH3GL interacting endocytic adaptor 1b [Source:ZFIN;Acc:ZDB-GENE-131121-110]) HSP 1 Score: 103.99 bits (258), Expect = 2.965e-22 Identity = 79/307 (25.73%), Postives = 146/307 (47.56%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEP--IHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P L++ + +P+A AFTET++A F+ + + V +G++V+SFP + + F N P + F +S SRL V LP + + D ++++ L L + P + ++NVD+++Y V+ G + P++++ +W+ D ++ L I+Y + A P P + ++F+V DG K+Q++ P N + + W++ + +S ++ +F LS GP P + QFS+EGS SG Q+ G+ +R+S K R S +Y+
Sbjct: 458 PSPLTMGPQDTLPVAAAFTETISAYFKGA--DPSCVVKITGEMVLSFPAGITRHFS-------NHPTPPVLTFTISHYSRLEQV--LPNPQLLCSDTMPTASDCKEFWVNMPNLMTHLKKVADQRPQATYYNVDMLKYQVSTQ----GIQSTPLNLAVSWR-GDPNSTDLRIDYKYN------AEAMLSPVPLTN----------IQFMVPVDGGVMKVQAMLPPATNQETQKILWKISELSQKSENGGVGALLGRFQLSEGPSKPSQLAVQFSSEGSTLSGCDFQLMGSGYRLSLVKKRF-SAKYL 731
BLAST of F-BAR domain only protein 2 vs. Ensembl Cavefish
Match: pstpip1a (proline-serine-threonine phosphatase interacting protein 1 [Source:NCBI gene;Acc:103046241]) HSP 1 Score: 51.2174 bits (121), Expect = 4.875e-6 Identity = 67/327 (20.49%), Postives = 141/327 (43.12%), Query Frame = 2
Query: 143 METLTFSDNFWGD---KHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSS-GSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQ--NNGNRSRDIERMEAKLKK-------AVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQC-----EFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTDPS--LNGNHIG 1063
M L F D FWG + G++ L Q + G ++ + + L+ E+ K ++++ S G+L+ + +K E H+ LS ++ +K ++++ + Q+ ++K + + + ++ V+ + I ++ Y R E + ++ + NN + E+++ K K+ A Y I++ + ++++ +C FQ+ E + +++ I H F +QC + E +T E +T D + FI+ K TG PP +FE + + + N + ++ S L GN G
Sbjct: 1 MTPLQFKDAFWGPDFVSNAGYEALTQRLYDGRRACKDMEELLKMRAMAEEKYGKELVAIARKAGGQSEIGTLKASFDQLKAQIENIGNLHIHLSGMLKEEVKRMEQFRERQKEQRKKFEGI---MEKVHKTKVSQYKKTIESKRSYEQRCREADEAEQAAEKINNTTTPKQAEKVQNKAKQCREAAGDAEKQYMSNIDQLDKIRQEWETTHESTCEVFQQQEGDRISILRNAIWVHCNH-FSMQCVKDDESYEEVRTVMEGCD--ITAD--INSFIELKRTGSSPPPPVLFESYYNREFAGESNGTARFGGGVIKRFSNLLQGNCSG 319
BLAST of F-BAR domain only protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007464.1 (pep scaffold:Pmarinus_7.0:GL477111:2188:43613:-1 gene:ENSPMAG00000006739.1 transcript:ENSPMAT00000007464.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 161.384 bits (407), Expect = 1.015e-44 Identity = 96/267 (35.96%), Postives = 151/267 (56.55%), Query Frame = 2
Query: 152 LTFSDNFWG-DKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSS-GSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPP 946
L F + WG +K+ GFD+LY NMK G S+ E DF+RE ++E+ KS KL+K + NS G+ P W+ + SE+ ++ H ELS+ + +I+ VQKY DEQ + K TK+ T + +T+ L++A++VY+++ E +L K GN ++ E+ + K +KA++ YK ++KY N + F+ KM E+ FQEIE HL+ + DFI FS + + F + R +T D L+E + +SK TGK P
Sbjct: 4 LHFVEPEWGGEKNNGFDILYHNMKHGQISTKEVADFIRERMTVEEVYAKSLTKLAKTASNNSQLGTFAPMWEVFRASSERLASCHQELSRKLMELIREVQKYGDEQTKQHKKTKEEVSGTLEAVQGMQSTTQALLKAKEVYNSKHQETERLKK----EGNH-KEYEKAQVKSRKAMEAYKVFVDKYANVRSDFEHKMTETAQRFQEIEEAHLQSLHDFIKAFSQAVEDTHTLIGQVHMEFRQQVRDITADNLIEKYSESKGTGKERP 265
BLAST of F-BAR domain only protein 2 vs. Ensembl Sea Lamprey
Match: gas7a (growth arrest-specific 7a [Source:ZFIN;Acc:ZDB-GENE-130128-1]) HSP 1 Score: 60.077 bits (144), Expect = 1.556e-9 Identity = 61/280 (21.79%), Postives = 128/280 (45.71%), Query Frame = 2
Query: 155 TFSDNFWGDK--------HQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSK-QINVNSSGSLQPFWQAIKELSEKRSTAHME----LSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLK--KAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQ-QTAFEKTQRKLTVDTLLEMFIKSKSTGKIPP 946
++ D+FW DK GF+VL G + S E +F+R+ +E+ K+ +KLS+ + + G+L W +K + H++ LS ++ + + +++ ++ K+ + N LL + + +AR V R E K ++ + + E M+A+++ + DD K ++ YN ++ +M+ S + +E +EQ++ ++R+ T L FN+ A ++ +K+ + E+++K TG + P
Sbjct: 138 SYCDHFWADKLDAHSKKATSGFNVLLAKQMKGQQMSREMAEFIRQRVKIEEEYAKNLSKLSQCPLALQEEGTLGESWAQVKISLSAEAEVHLKFAAKLSSEVEKPLFSFREHFGKEMRKK------EHHIANHRKLLTTRYSSVQKARKVLAKRQRELEMKVKHNEIKPSNKAEEEIMKARMRSTQGGDDLKKCVDLYNQAQFRWFEEMVTSSLELERLEVERIEQIEQHLNRY-TQLRHETDVFNQSTMEAVNQSLQKVDPNRDRELWVKDTRTGSVRP 410
BLAST of F-BAR domain only protein 2 vs. Ensembl Nematostella
Match: EDO36238 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ57]) HSP 1 Score: 136.346 bits (342), Expect = 8.968e-36 Identity = 90/272 (33.09%), Postives = 157/272 (57.72%), Query Frame = 2
Query: 176 GDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSK-QINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRF-STHLF------KVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFED 967
G+K+ GFDVLY NMK G +S++ ++F+RE ++E++ KS KL+K + + G+ +P W ++ +EK S AH ++ +Q ++K +++Y D+Q+ + K+ KD T I + + L +A++ Y+AR EF + ++ +G ++++E+ EAK+KKA ++YK L+EK F KM+++C FQ+IE HL+ + + + +H+ KV EF EQ A L V+ LL+ F++SK TG P+ FE+
Sbjct: 1 GEKNAGFDVLYHNMKYGNNASTKLVEFIRERSAIEENYCKSLVKLAKSACSASQLGTFEPLWGVLRVATEKLSNAHHQVVVRLQELVKEIKEYGDKQKERHKAAKDEFTTTAEIVQTIQTMTAALTKAKETYYARCQEFER----NKRDGTSTKELEKAEAKMKKAAEEYKALVEKREIIRNDFHDKMVDTCRKFQQIEEEHLQIISRHLETYIGSHMAGWEIMEKVHTEFREQVAA-------LAVEKLLDQFVRSKGTGMNIPEVITFEE 261
BLAST of F-BAR domain only protein 2 vs. Ensembl Nematostella
Match: EDO40558 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6P0]) HSP 1 Score: 62.3882 bits (150), Expect = 1.300e-10 Identity = 63/271 (23.25%), Postives = 122/271 (45.02%), Query Frame = 2
Query: 2258 VHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPA--SPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLSTNQ-------SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGR 3040
V +G + +SFP S++ + + + L + F + S L + P + Q+ SY F + + LR+ A S ++N+DI++Y+V +G + P+ + + W+ + +++ I+Y + N+ S +P P V + +G MQS P + W+++ RA W + ++S++Q S + +KF LS GP TP + QF+ G+ S + ++ +R+S K + SG+
Sbjct: 4 VKVTGDITVSFPASLVTRLCNRESSPL-----LTFQIKGTSSLEQILPNKSLILSEGQLSGGDIVSYK-----FIMPSLIEHLRKQLEATSSAYYNIDIMKYEV----HTSGIQSTPLQLCSYWK-CEQPTTNIRIDYRY---NSSCMS-----APC--------PLSNVSIIAPVNGGVTIMQSKPSATWSAENERAVWVIPEISSSQEPDGQYLSIVGAKFDLSGGPSTPSRIAVQFTCNGATISKLNFELKSEDYRLSLVKKKFSSGK 243
BLAST of F-BAR domain only protein 2 vs. Ensembl Nematostella
Match: EDO34808 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNC2]) HSP 1 Score: 56.6102 bits (135), Expect = 3.804e-8 Identity = 77/340 (22.65%), Postives = 149/340 (43.82%), Query Frame = 2
Query: 158 FSDNFWGDKH---QGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSS-GSLQPFWQAIKELSEKRSTAHMELSQNI-QLIIKAVQKYMDEQQLKQKSTKDLDLQTQ--------NINSLLVNTSTQLIRARD---------VYHARFLEFHKLHKS-DQNNGNRSRDIERMEAKLKKAVDD--YKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQC-EFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFED---AESSDIKSQDNKIQKESTDILTDPSLNGNHIGDVITGNLVN 1090
F D FWG + GFD L + M+ G ++ E +F+++ +E+ KS +L+K G+L+ W +++ +E AH+ L+Q + + K +Q++ + Q+ +K +D ++Q N++ L T Q R ++ V A E LH S + + KL D Y+ + ++T ++ +M CN FQ +E + +++++ ++ +L + C + +E ++ VD +++FI + TG P H +E+ +SS + T L+ S+N IG I G+L +
Sbjct: 4 FVDCFWGTEFTSTAGFDALSKRMRDGKQTCQEMEEFVKQRADIEEKYGKSLMRLAKTSEAKDEIGTLKSSWDSLRNETENIGKAHVALAQQLLDSLEKGLQEFRENQKETRKKLEDSVKRSQRNKKTCYENLHKL-KRTYEQKCREKEAADDALKKSVSMAAKDEEKTLHSSIVYGHTTEKAPVLVRSPKLSSVEHDSAYQTSVRVLDDTRVVWEREMATCCNVFQNLEEERIAFLRNWMWLYA-NLGSINCVKVDEMYEVVRQSLEGCNVDQDIKLFISMRQTGSERPSHIDYENYYMVQSS-----------QKTSPLSGGSVN---IGGPIPGSLTH 327
BLAST of F-BAR domain only protein 2 vs. Ensembl Nematostella
Match: EDO43872 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXM7]) HSP 1 Score: 51.9878 bits (123), Expect = 9.656e-7 Identity = 54/258 (20.93%), Postives = 113/258 (43.80%), Query Frame = 2
Query: 158 FSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLS----KQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQL-IIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLH------KSDQNNGNRSRDIERMEAKLKKAVD-------DYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQ 877
F ++FW + +G++ L ++ + G E E +E S S +KLS K + + G+L+ W+ I E + H L+ + K ++ +++ Q K+ K ++++ + + + ++ + H++ E LH K + +DI ++EAK+KK ++ DY+ + K T ++++ M + C + +++E + +KD S + L V E Q +E Q
Sbjct: 4 FEESFW--EQKGYEELRKSCRQGSDFCKEIAAIFNERSKIELSYADSLSKLSVKAQKLLAKDVVGTLKSSWEKISWNIESEADIHRTLANQLHGEAAKQIKAFVETQS---KTRKPVEVEVEKAYKNFSDRLSDSLKKKGASHSKSKEVETLHDQMEDTKQGKGKAVSDKDITKLEAKIKKGMESAIKSDKDYREMYMKTERTRLEWEATMSKYCQTCEKLEEERVGHLKDMFSLYGNMLAAV---IPELQQVYESIQ 253
BLAST of F-BAR domain only protein 2 vs. Ensembl Medaka
Match: fcho1 (F-BAR domain only protein 1 [Source:NCBI gene;Acc:101171653]) HSP 1 Score: 177.563 bits (449), Expect = 7.662e-45 Identity = 92/274 (33.58%), Postives = 150/274 (54.74%), Query Frame = 2
Query: 152 LTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDA 970
+ F DNFWG+K+ GFDVLY NMK G ++ E +F+RE ++E++ +KS +KL+K N + G+ P W + S+K + H+EL + + +I+ + KY +EQ + TK+ + T L S+ L ++++ YH + LE +L K G +++E+ E K KKA + + IEKYN +F+ KM ES +FQEIE HL QMK + +S + + + F++ + +DTL++ + K TGK P FE+
Sbjct: 1 MAFQDNFWGEKNAGFDVLYHNMKHGQLATKELAEFVRERAAIEETYSKSMSKLAKMASNGSPQGTFAPMWDVFRVSSDKVALCHLELMKKMNDLIREINKYGEEQVKIHRKTKEKMVGTVEAVQALQVQSSHLQKSKEGYHGKCLELDRLRK----EGAPQKELEKAELKSKKAAESFALCIEKYNRVGGEFEQKMSESAQNFQEIEEAHLRQMKQLMKSYSHSIEDTHVQVGQVHEEFKQNVENIGIDTLIQKLAEQKGTGKDRPAPVGFEEC 270 HSP 2 Score: 80.4925 bits (197), Expect = 8.604e-15 Identity = 86/345 (24.93%), Postives = 154/345 (44.64%), Query Frame = 2
Query: 2036 PLPAKITPPRSASTVPFSNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPI-HFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLSTNQSSIKSKFMLSNGP------GTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P PA+I AS + + + ++ R + P +S+++ E P+A A TE +NA F+ N V +G L +SFP + + F + N PI F L SR+ + LP K + +S + ++ L L P + ++NV +++Y V++ AP+ +SA Q + T+ T V SL + PA + ++++ V+ L+ D + +Q PP+ WN++ R W+L +LS S S + ++ G P + QF G+ SG+ +++ G+R+R+S K R +G+Y+
Sbjct: 912 PSPARIG---QASPLSYQHQELQQRSLH------LSRGPSPISLSAQEAWPVAAAITEYINAYFKGGQHNR-CLVKITGDLTMSFPAGITRIFSA------NPNIPILSFRLVNISRIDHF--LPNQKLLYSDPSQTDPNSRDFWFNMQALQLHLQREAELNPQASYYNVGLLKYQVSSQ----DPGRAPLLLSAECQRSGTV--------------TRV-SLDYHCCPATAPSTQLT---SVQVLLPLDHAATDVQCQPPASWNAEERRLLWKLPNLSPTNHSKGSGTLCASWQCLEVPRGPPPSLAVQFVGSGTSLSGMGVELVGSRYRMSLVKKRFATGKYM 1216
BLAST of F-BAR domain only protein 2 vs. Ensembl Medaka
Match: fcho2 (FCH and mu domain containing endocytic adaptor 2 [Source:NCBI gene;Acc:101175493]) HSP 1 Score: 168.318 bits (425), Expect = 2.184e-42 Identity = 96/283 (33.92%), Postives = 158/283 (55.83%), Query Frame = 2
Query: 146 ETLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQI-NVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQT----QNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESS 979
E L N+ G+K+ GFDVLY NMK G S+ E DF+RE ++E++ +S KL K N + G+ P W K +EK++ HM+L++ +Q +IK VQKY++EQ K TK+ T QNI ++ S L +++++Y+A+ +E +L K G RD+++ K KKA + YK +EKY ++F+ KM E+ FQ+IE H+ Q+K+ I +S ++ + + E F + +V++L++ +SK TGK P FE+ ++
Sbjct: 13 EPLLLCRNY-GEKNNGFDVLYHNMKHGQISTKELTDFIRERSTIEEAYARSMTKLVKTAGNFSQLGTFAPVWDVFKSSTEKQAVCHMDLARKLQELIKEVQKYIEEQAKAHKKTKEEVAPTLEAVQNIQTI----SQSLQKSKEIYNAKTVEQERLRK----EGATQRDVDKAGVKAKKATESYKSYVEKYATAKSEFEQKMAETAQKFQDIEENHILQLKEIIHSYSEYVEETHVQIGEVHKEFVRNIENTSVESLIQKLSESKGTGKERPGPVEFEECNAA 286 HSP 2 Score: 123.635 bits (309), Expect = 2.368e-28 Identity = 90/305 (29.51%), Postives = 158/305 (51.80%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRL-DLST-----NQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P +++ S + +P+A+AFTE+VNA F+ + T V +G + +SFP +++ F S + + F L ASRL + LP + ++ DS S + ++ L L P++ ++NVDI++Y V ++ G + P++++ W+ T + + L ++Y + + + SP N ++ LV DG +QSLP SIW+S+ + W+L DLS+ SI++KF LS+GP P + QF +EG+ SGV +++ G+ +R+S K R +GRY+
Sbjct: 548 PSPVTLASQDALPIAVAFTESVNAYFKGA-DPTKCIVKITGDMTLSFPMGIIKVFTSNPSPAV-----LTFKLKNASRLEQI--LPNVQLLHSDPSQSDSDSKSFWFNMQALTTYLRKASEQNPSASYYNVDILKYQVQSD----GIHSTPLNLAVYWKCTPS-TTDLRVDYRYNPESMD--------SPGSLTNLQV--------LVPVDGGVTSVQSLPNSIWSSEQNKCLWKLSDLSSKSENEGAGSIRAKFDLSHGPSNPSTLAVQFMSEGATLSGVDMELLGSGYRLSLSKKRFATGRYM 823
BLAST of F-BAR domain only protein 2 vs. Ensembl Medaka
Match: sgip1a (SH3GL interacting endocytic adaptor 1 [Source:NCBI gene;Acc:101164635]) HSP 1 Score: 120.939 bits (302), Expect = 2.114e-27 Identity = 88/306 (28.76%), Postives = 156/306 (50.98%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPT--SKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQS-LPPSIWNSDLGRASWRL-DLSTNQ-----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGR 3040
P L++ + + +P+A AFTETVNA F+ + + V G++V+SFP + + F + + + F ++ SRL +V P P D Q DS ++++ L L + +P + ++NVD+++Y V+ G ++P++++ +W+ T ++ L I+Y + N E S +P N V+FLV DG K+Q+ LPP+ WN++ R W++ D+S S+ ++F L+ GP P P+ QF++EGS SG +++ G +R S K R +G+
Sbjct: 628 PSPLTMGAQDTLPVAAAFTETVNAVFKGADPSK-CVVKIIGEMVLSFPAGITRHFANNPSPAV-----LTFSITNYSRLEHVLPNPQLLCCDTTTQAKA---DSKDFWVNMPNLISHLKKVSEQKPQATYYNVDMLKYQVSTQ----GLQSSPLNLAVSWRCEST-STDLRIDYKY---NGEAMS-----TPMALNN--------VQFLVPVDGGVSKLQAVLPPAAWNAEQQRILWKIPDISQKSENGGVGSLLARFQLTEGPSKPAPLAVQFTSEGSTLSGCDIELAGPGYRFSLIKKRFAAGQ 903
BLAST of F-BAR domain only protein 2 vs. Ensembl Medaka
Match: SGIP1 (SH3-containing GRB2-like protein 3-interacting protein 1 [Source:NCBI gene;Acc:105356194]) HSP 1 Score: 117.857 bits (294), Expect = 1.725e-26 Identity = 86/318 (27.04%), Postives = 160/318 (50.31%), Query Frame = 2
Query: 2123 IPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPI-HFCLSQASRLRNVEPLPTSKDINIQIDNPTD--DSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSL-PPSIWNSDLGRASWRLDLSTNQS------SIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
+PS P L++ + +P+A AFTET+NA F+ + + V +G++V+SFP + + F S + +PI F +S +RL V P P + D+ T+ + ++++ L L + +P + ++NVD+I+Y V+ G + P++++ +W+ +D+ ++ L I+Y + NTE + P ++FLV D K+Q++ PP+IWN + W + +++S ++ +F + GP P + QFS+EGS SG +Q+ G +R+S K R +G+Y+
Sbjct: 584 MPSTGCSRGPSPLTMGPQDTLPVAAAFTETINAYFKGA-DPSKCLVKITGEIVLSFPAGITRHFAS------HPTQPILTFSISNYNRLEQVLPNPQL----LCCDSTTNVVGTKEFWVNMPNLLSHLKKVAEQKPQATYYNVDMIKYQVSAE----GIQSTPLNLALSWR-SDSTSTDLRIDYKY---NTEAMAAPV-------------PLHNIQFLVPVDAGVAKLQAMVPPAIWNPEHRTIQWNISSLSHRSENGGVGALLGRFQMVEGPCKPSQLAVQFSSEGSTLSGCDIQLVGTGYRLSLVKKRFAAGKYL 869
BLAST of F-BAR domain only protein 2 vs. Ensembl Medaka
Match: sgip1a (SH3GL interacting endocytic adaptor 1 [Source:NCBI gene;Acc:101164635]) HSP 1 Score: 108.227 bits (269), Expect = 1.832e-23 Identity = 80/306 (26.14%), Postives = 146/306 (47.71%), Query Frame = 2
Query: 2150 PVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQS-LPPSIWNSDLGRASWRL-DLSTNQ-----SSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYV 3046
P L++ + + +P+A AFTETVNA F+ + + +V++F + + E V L P C ++ + DS ++++ L L + +P + ++NVD+++Y V+ G ++P++++ +W+ T ++ L I+Y + N E S +P N V+FLV DG K+Q+ LPP+ WN++ R W++ D+S S+ ++F L+ GP P P+ QF++EGS SG +++ G +R S K R +G+Y+
Sbjct: 612 PSPLTMGAQDTLPVAAAFTETVNAVFKGADPSK----CVVKIIVLTFSITNYSRLEHV------LPNPQLLCCDTTTQAKA-------------------DSKDFWVNMPNLISHLKKVSEQKPQATYYNVDMLKYQVSTQ----GLQSSPLNLAVSWRCEST-STDLRIDYKY---NGEAMS-----TPMALNN--------VQFLVPVDGGVSKLQAVLPPAAWNAEQQRILWKIPDISQKSENGGVGSLLARFQLTEGPSKPAPLAVQFTSEGSTLSGCDIELAGPGYRFSLIKKRFAAGKYL 867
BLAST of F-BAR domain only protein 2 vs. Planmine SMEST
Match: SMESG000078045.1 (SMESG000078045.1) HSP 1 Score: 1950.64 bits (5052), Expect = 0.000e+0 Identity = 978/980 (99.80%), Postives = 980/980 (100.00%), Query Frame = 2
Query: 143 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTDPSLNGNHIGDVITGNLVNXXXXXXXXXTHVSNVNITTPNAKDSINDIFDQLSNISDNNSINQTTVSHIDGGTVSIPIKKQKKYNNIFRRKRNSPSNGVTQKQLQDTDKEKSSQSLGEYMVDDEGYTIKPNDPWPXXXXXXXXXXXXXXXXXXXIFKAIKIEIKPKDNKSDSSSIPDNDLPIKAKSKNNDNLELFKAVQAFKISPNIFRDGNRRTGDSRSNTPSLPNVLADDGSPPTSTRLNSISVSIRDSRRKKNSRSQSEQAQSLAQPYFQVEFTNSFESNGLDLAGVTSDPFNSRFESFQSSKADLPLKTNENKIDPWGSSTVNDKSIQPPPLPAKITPPRSASTVPFSNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEPSTNTTGFCV 3082
METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTDPSLNGNHIGDVITGNLVNIDSSSDISSTHVSNVNITTPNAKDSINDIFDQLSNISDNNSINQTTVSHIDGGTVSIPIKKQKKYNNIFRRKRNSPSNGVTQKQLQDTDKEKSSQSLGEYMVDDEGYTIKPNDPWPDHNQ+SSSDSSSDDDNADNIFKAIKIEIKPKDNKSDSSSIPDNDLPIKAKSKNNDNLELFKAVQAFKISPNIFRDGNRRTGDSRSNTPSLPNVLADDGSPPTSTRLNSISVSIRDSRRKKNSRSQSEQAQSLAQPYFQVEFTNSFESNGLDLAGVTSDPFNSRFESFQSSKADLPLKTNENKIDPWGSSTVNDKSIQPPPLPAKITPPRSASTVPFSNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCL+QASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEPSTNTTGFCV
Sbjct: 1 METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTDPSLNGNHIGDVITGNLVNIDSSSDISSTHVSNVNITTPNAKDSINDIFDQLSNISDNNSINQTTVSHIDGGTVSIPIKKQKKYNNIFRRKRNSPSNGVTQKQLQDTDKEKSSQSLGEYMVDDEGYTIKPNDPWPDHNQHSSSDSSSDDDNADNIFKAIKIEIKPKDNKSDSSSIPDNDLPIKAKSKNNDNLELFKAVQAFKISPNIFRDGNRRTGDSRSNTPSLPNVLADDGSPPTSTRLNSISVSIRDSRRKKNSRSQSEQAQSLAQPYFQVEFTNSFESNGLDLAGVTSDPFNSRFESFQSSKADLPLKTNENKIDPWGSSTVNDKSIQPPPLPAKITPPRSASTVPFSNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLTQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEPSTNTTGFCV 980
BLAST of F-BAR domain only protein 2 vs. Planmine SMEST
Match: SMESG000078045.1 (SMESG000078045.1) HSP 1 Score: 1896.32 bits (4911), Expect = 0.000e+0 Identity = 954/956 (99.79%), Postives = 956/956 (100.00%), Query Frame = 2
Query: 215 MKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTDPSLNGNHIGDVITGNLVNXXXXXXXXXTHVSNVNITTPNAKDSINDIFDQLSNISDNNSINQTTVSHIDGGTVSIPIKKQKKYNNIFRRKRNSPSNGVTQKQLQDTDKEKSSQSLGEYMVDDEGYTIKPNDPWPXXXXXXXXXXXXXXXXXXXIFKAIKIEIKPKDNKSDSSSIPDNDLPIKAKSKNNDNLELFKAVQAFKISPNIFRDGNRRTGDSRSNTPSLPNVLADDGSPPTSTRLNSISVSIRDSRRKKNSRSQSEQAQSLAQPYFQVEFTNSFESNGLDLAGVTSDPFNSRFESFQSSKADLPLKTNENKIDPWGSSTVNDKSIQPPPLPAKITPPRSASTVPFSNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLSQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEPSTNTTGFCV 3082
MKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTDPSLNGNHIGDVITGNLVNIDSSSDISSTHVSNVNITTPNAKDSINDIFDQLSNISDNNSINQTTVSHIDGGTVSIPIKKQKKYNNIFRRKRNSPSNGVTQKQLQDTDKEKSSQSLGEYMVDDEGYTIKPNDPWPDHNQ+SSSDSSSDDDNADNIFKAIKIEIKPKDNKSDSSSIPDNDLPIKAKSKNNDNLELFKAVQAFKISPNIFRDGNRRTGDSRSNTPSLPNVLADDGSPPTSTRLNSISVSIRDSRRKKNSRSQSEQAQSLAQPYFQVEFTNSFESNGLDLAGVTSDPFNSRFESFQSSKADLPLKTNENKIDPWGSSTVNDKSIQPPPLPAKITPPRSASTVPFSNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCL+QASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEPSTNTTGFCV
Sbjct: 1 MKTGVKSSSEFLDFLREIYSMEDSCTKSWNKLSKQINVNSSGSLQPFWQAIKELSEKRSTAHMELSQNIQLIIKAVQKYMDEQQLKQKSTKDLDLQTQNINSLLVNTSTQLIRARDVYHARFLEFHKLHKSDQNNGNRSRDIERMEAKLKKAVDDYKYLIEKYNNTCTKFKSKMLESCNSFQEIETYHLEQMKDFISRFSTHLFKVQCEFNEQQTAFEKTQRKLTVDTLLEMFIKSKSTGKIPPKHAMFEDAESSDIKSQDNKIQKESTDILTDPSLNGNHIGDVITGNLVNIDSSSDISSTHVSNVNITTPNAKDSINDIFDQLSNISDNNSINQTTVSHIDGGTVSIPIKKQKKYNNIFRRKRNSPSNGVTQKQLQDTDKEKSSQSLGEYMVDDEGYTIKPNDPWPDHNQHSSSDSSSDDDNADNIFKAIKIEIKPKDNKSDSSSIPDNDLPIKAKSKNNDNLELFKAVQAFKISPNIFRDGNRRTGDSRSNTPSLPNVLADDGSPPTSTRLNSISVSIRDSRRKKNSRSQSEQAQSLAQPYFQVEFTNSFESNGLDLAGVTSDPFNSRFESFQSSKADLPLKTNENKIDPWGSSTVNDKSIQPPPLPAKITPPRSASTVPFSNSTIESRKFSSIPSNTIPATPVRLSINSIEGIPLAIAFTETVNAKFRESFSNTPHDVHTSGQLVISFPCSMLQQFESVGENQLNLAEPIHFCLTQASRLRNVEPLPTSKDINIQIDNPTDDSYSIYIDLFTLHKKLTTLRRNEPASPFFNVDIIRYDVTNNVRPNGSINAPVHISANWQITDTLASHLMINYNFQWPNTEVASLTFRPSPAKSGNSEIRPHGEVRFLVIADGSPFKMQSLPPSIWNSDLGRASWRLDLSTNQSSIKSKFMLSNGPGTPQPVVCQFSAEGSIESGVLLQVTGNRFRISRHKYRLISGRYVWEPSTNTTGFCV 956 The following BLAST results are available for this feature:
BLAST of F-BAR domain only protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of F-BAR domain only protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of F-BAR domain only protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of F-BAR domain only protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of F-BAR domain only protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of F-BAR domain only protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014362 ID=SMED30014362|Name=F-BAR domain only protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=3154bpback to top protein sequence of SMED30014362-orf-1 >SMED30014362-orf-1 ID=SMED30014362-orf-1|Name=SMED30014362-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=981bp METLTFSDNFWGDKHQGFDVLYQNMKTGVKSSSEFLDFLREIYSMEDSCTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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