Choline dehydrogenase

Overview
NameCholine dehydrogenase
Smed IDSMED30014360
Length (bp)2267
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Choline dehydrogenase (SMED30014360) t-SNE clustered cells

Violin plots show distribution of expression levels for Choline dehydrogenase (SMED30014360) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Choline dehydrogenase (SMED30014360) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Choline dehydrogenase (SMED30014360) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30014360

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30014360h1SMcG0007578 SmedASXL_014058SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30014360h1SMcG0007578 Contig630GPL15192PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014360h1SMcG0007578 Contig49073uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30014360h1SMcG0007578 Contig49073newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30014360h1SMcG0007578 dd_Smed_v4_1744_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014360h1SMcG0007578 dd_Smed_v4_1744_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014360h1SMcG0007578 dd_Smed_v4_1744_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30014360h1SMcG0007578 dd_Smed_v4_1744_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30014360h1SMcG0007578 dd_Smed_v6_1744_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30014360h1SMcG0007578 dd_Smed_v4_1744_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Category 4 cellSMED30014360h1SMcG0007578 dd_Smed_v4_1744_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Choline dehydrogenase vs. Ensembl Human
Match: CHDH (choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24288])

HSP 1 Score: 593.193 bits (1528), Expect = 0.000e+0
Identity = 280/560 (50.00%), Postives = 383/560 (68.39%), Query Frame = 2
Query:  302 QTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            +++ +  YV+VGAGSAGCVLA RL  D    V L+EAG  D        +  I +P AL   +    +NWC+ T+ Q  L+ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW++QGA GW Y+ CLPYF+KA+ HE G + Y G +GPL V+R K N  LH  +++A  QAGY   ED NGF+QEGFG  DMTIH+G+RWS+A AYL P +   +L    ++LV++V+FEG RA+GV+ + K G+     A+KEVIL GGAINSP LL+LSG+G+ ++LKK  + +V H+PGVG+N QDH  IY++  C +P+TL S Q P  K  +  +W    TG GAT HL +GGFIRS+  V HPDIQFHF P  ++DHGR      ++Q+ V P+R  S G + L S +P++HP I PNY S+E DI +F+  +KLTREI AQ A   +RG+E+ PG  +Q+DK+++ F++  ++  YHP+ TCKMG  +    VVD Q RV+GVENLRVVDAS+MPS+VSGN NAPT+MIAEK AD+I G+  L   +VP++ P+  + QR
Sbjct:   36 ESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQGHELGASRYRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRWSAACAYLHPALSRTNLKAEAETLVSRVLFEGTRAVGVEYV-KNGQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTRPITLHSAQKPLRKVCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDHGRVPTQQEAYQVHVGPMRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRGKELQPGSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPALWDKDVPVYKPRTLATQR 594          
BLAST of Choline dehydrogenase vs. Ensembl Human
Match: CHDH (choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24288])

HSP 1 Score: 115.161 bits (287), Expect = 4.049e-29
Identity = 55/120 (45.83%), Postives = 77/120 (64.17%), Query Frame = 2
Query:  302 QTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGA 640
            +++ +  YV+VGAGSAGCVLA RL  D    V L+EAG  D        +  I +P AL   +    +NWC+ T+ Q  L+ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW++QGA
Sbjct:   36 ESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGA 155          
BLAST of Choline dehydrogenase vs. Ensembl Human
Match: CHDH (choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24288])

HSP 1 Score: 69.3218 bits (168), Expect = 1.770e-13
Identity = 36/91 (39.56%), Postives = 52/91 (57.14%), Query Frame = 2
Query:  302 QTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGK 553
            +++ +  YV+VGAGSAGCVLA RL  D    V L+EAG  D        +  I +P AL   +    +NWC+ T+ Q  L+ R ++ PRG+
Sbjct:   36 ESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGR 126          
BLAST of Choline dehydrogenase vs. Ensembl Celegans
Match: C34C6.4 (pep chromosome:WBcel235:II:8696591:8698928:-1 gene:WBGene00007917.1 transcript:C34C6.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C34C6.4)

HSP 1 Score: 522.316 bits (1344), Expect = 1.027e-177
Identity = 258/557 (46.32%), Postives = 357/557 (64.09%), Query Frame = 2
Query:  323 YVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK--NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAG---ENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKL----------ENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKK---KVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCR-VVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKP-LPKLNVPIW 1933
            ++IVGAGSAGCVLANRL  D  N V L+EAG  D   +  I +P AL   +    +NW + T  Q +L  R  + PRG+V GGSS++N M Y+RGH YDY+RWEK+GASGW+Y++CLPYFKKAE +       + Y G NGPL+V +      LH+ W+  G +   G   D NG +QEG    DMTIH GERWS++KAY+ P+    +L  ++    T+V+F+  +AIG++ + K   +          E +    +VIL GGAIN+P LL+LSGVG  + L+ H + IV ++PGVG+N QDH  IYV+ +  +PVTL++  S +F     K+  +W  ++TG GA+ HL +GGF RS+  VTHPDIQFHF P  + D GR   T H +Q+ V P+RS+SKG I L + DP+  P I+PNY   + D  EF+  I+++RE+ A  AFDE+RG+E++PGP  Q+D  ++ F+K  +   YHP+ TCKMG+ N    VV+ +   V G ENL+VVDASVMPSIVSGN NAP +M+AE+ AD+I  KK  LP  +  +W
Sbjct:   40 HIIVGAGSAGCVLANRLTEDPSNRVLLIEAGPVDHKWDWRIHMPAALMYNLCSDTYNWHYHTTAQKNLGNRVFYWPRGRVWGGSSTLNAMCYVRGHAYDYNRWEKEGASGWNYANCLPYFKKAETYSDATGPNDPYRGNNGPLYVKKGDAENPLHKAWLNVGKEHPLGWTNDMNGEKQEGISTMDMTIHNGERWSASKAYVHPIRNRPNLITSSGITCTRVLFDTNKAIGIEFIRKLNFVGTDSIDSYSREKIYCQGDVILAGGAINTPQLLMLSGVGPADHLRSHEIPIVANLPGVGQNLQDHLEIYVQQESTQPVTLYNKSSWKFPHNMIKIGLEWFTNRTGLGASSHLETGGFARSDDTVTHPDIQFHFLPSTVHDDGRTNGTCHGYQVHVGPMRSQSKGYIMLQAKDPRRAPIINPNYMEEDSDWREFRKCIRVSRELFASKAFDEFRGKELAPGPDCQSDADIDRFVKEKAASAYHPSCTCKMGSENDKMAVVNPETMGVYGTENLKVVDASVMPSIVSGNLNAPVIMMAERAADLIKHKKQLLPPSDANVW 596          
BLAST of Choline dehydrogenase vs. Ensembl Fly
Match: CG9518 (gene:FBgn0030590 transcript:FBtr0073983)

HSP 1 Score: 306.22 bits (783), Expect = 4.693e-93
Identity = 203/571 (35.55%), Postives = 298/571 (52.19%), Query Frame = 2
Query:  299 LQTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETKPQ----LHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHE---AGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFE--GKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIY-VRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSG-GFIR---SEANVTHPDIQFHFFPGLL-LDHGRQT-----MTSHSFQMFVSP-------------LRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQ-------TDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMI 1891
            L    + D+++VG+GSAG V+ANRL    K  V L+EAG  D+N    +P +L   +   + +W ++T+P     L +   +   PRG+V+GGSS +N M+Y+RG+ +DYD W   G  GW Y + L YFKK+E +       N YHG  G L V  S  +  L   +V+AGTQ GY +  D NG +Q GF     TI +G R S+AKA+L P+   K+  ++ +S VT+VI E    RA  V+   K GK+  + A +EVI+  GAIN+P L++LSG+G    L+KH + +++ +P VG+N QDH  +  + +   KPV +  +Q       V   +   + G   T+    G  F+    S  ++  PDIQFH  P  +  D+G +      +    +Q    P             LR  S+GS+ L S +P  +P I+ NY     D        K+   +     F ++ G  +   PL         +D  +E  ++  S   YHP  T KMG     + VVD + RV GV  LRV+DAS+MP+I SGNTNAP +MIAEK AD+I
Sbjct:   51 LNLYPEYDFIVVGSGSAGAVVANRLSEVRKWKVLLIEAGP-DENEISDVP-SLAAYLQLSKLDWAYKTEPSTKACLGMQNNRCNWPRGRVLGGSSVLNYMLYVRGNRHDYDHWASLGNPGWDYDNVLRYFKKSEDNRNPYLANNKYHGRGGLLTVQESPWHSPLVAAFVEAGTQLGYDN-RDINGAKQAGFMIAQGTIRRGSRCSTAKAFLRPIRMRKNFHLSMNSHVTRVIIEPGTMRAQAVE-FVKHGKVYRIAARREVIISAGAINTPQLMMLSGLGPRKHLEKHGIRVLQDLP-VGENMQDHVGMGGLTFLVDKPVAI--VQDRFNPTAVTFQYVLRERGPMTTLGGVEGLAFVHTPYSNRSLDWPDIQFHMAPASINSDNGARVKKVLGLKESVYQEVYHPIANKDSWTIMPLLLRPRSRGSVKLRSANPFHYPLINANYFDDPLDAKTLVEGAKIALRVAEAQVFKQF-GSRLWRKPLPNCKQHKFLSDAYLECHVRTISMTIYHPCGTAKMGPAWDPEAVVDPRLRVYGVRGLRVIDASIMPTISSGNTNAPVIMIAEKGADLI 613          
BLAST of Choline dehydrogenase vs. Ensembl Fly
Match: CG9518 (gene:FBgn0030590 transcript:FBtr0343598)

HSP 1 Score: 306.22 bits (783), Expect = 4.693e-93
Identity = 203/571 (35.55%), Postives = 298/571 (52.19%), Query Frame = 2
Query:  299 LQTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETKPQ----LHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHE---AGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFE--GKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIY-VRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSG-GFIR---SEANVTHPDIQFHFFPGLL-LDHGRQT-----MTSHSFQMFVSP-------------LRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQ-------TDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMI 1891
            L    + D+++VG+GSAG V+ANRL    K  V L+EAG  D+N    +P +L   +   + +W ++T+P     L +   +   PRG+V+GGSS +N M+Y+RG+ +DYD W   G  GW Y + L YFKK+E +       N YHG  G L V  S  +  L   +V+AGTQ GY +  D NG +Q GF     TI +G R S+AKA+L P+   K+  ++ +S VT+VI E    RA  V+   K GK+  + A +EVI+  GAIN+P L++LSG+G    L+KH + +++ +P VG+N QDH  +  + +   KPV +  +Q       V   +   + G   T+    G  F+    S  ++  PDIQFH  P  +  D+G +      +    +Q    P             LR  S+GS+ L S +P  +P I+ NY     D        K+   +     F ++ G  +   PL         +D  +E  ++  S   YHP  T KMG     + VVD + RV GV  LRV+DAS+MP+I SGNTNAP +MIAEK AD+I
Sbjct:   51 LNLYPEYDFIVVGSGSAGAVVANRLSEVRKWKVLLIEAGP-DENEISDVP-SLAAYLQLSKLDWAYKTEPSTKACLGMQNNRCNWPRGRVLGGSSVLNYMLYVRGNRHDYDHWASLGNPGWDYDNVLRYFKKSEDNRNPYLANNKYHGRGGLLTVQESPWHSPLVAAFVEAGTQLGYDN-RDINGAKQAGFMIAQGTIRRGSRCSTAKAFLRPIRMRKNFHLSMNSHVTRVIIEPGTMRAQAVE-FVKHGKVYRIAARREVIISAGAINTPQLMMLSGLGPRKHLEKHGIRVLQDLP-VGENMQDHVGMGGLTFLVDKPVAI--VQDRFNPTAVTFQYVLRERGPMTTLGGVEGLAFVHTPYSNRSLDWPDIQFHMAPASINSDNGARVKKVLGLKESVYQEVYHPIANKDSWTIMPLLLRPRSRGSVKLRSANPFHYPLINANYFDDPLDAKTLVEGAKIALRVAEAQVFKQF-GSRLWRKPLPNCKQHKFLSDAYLECHVRTISMTIYHPCGTAKMGPAWDPEAVVDPRLRVYGVRGLRVIDASIMPTISSGNTNAPVIMIAEKGADLI 613          
BLAST of Choline dehydrogenase vs. Ensembl Fly
Match: CG9518 (gene:FBgn0030590 transcript:FBtr0344175)

HSP 1 Score: 306.22 bits (783), Expect = 4.693e-93
Identity = 203/571 (35.55%), Postives = 298/571 (52.19%), Query Frame = 2
Query:  299 LQTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETKPQ----LHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHE---AGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFE--GKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIY-VRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSG-GFIR---SEANVTHPDIQFHFFPGLL-LDHGRQT-----MTSHSFQMFVSP-------------LRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQ-------TDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMI 1891
            L    + D+++VG+GSAG V+ANRL    K  V L+EAG  D+N    +P +L   +   + +W ++T+P     L +   +   PRG+V+GGSS +N M+Y+RG+ +DYD W   G  GW Y + L YFKK+E +       N YHG  G L V  S  +  L   +V+AGTQ GY +  D NG +Q GF     TI +G R S+AKA+L P+   K+  ++ +S VT+VI E    RA  V+   K GK+  + A +EVI+  GAIN+P L++LSG+G    L+KH + +++ +P VG+N QDH  +  + +   KPV +  +Q       V   +   + G   T+    G  F+    S  ++  PDIQFH  P  +  D+G +      +    +Q    P             LR  S+GS+ L S +P  +P I+ NY     D        K+   +     F ++ G  +   PL         +D  +E  ++  S   YHP  T KMG     + VVD + RV GV  LRV+DAS+MP+I SGNTNAP +MIAEK AD+I
Sbjct:   51 LNLYPEYDFIVVGSGSAGAVVANRLSEVRKWKVLLIEAGP-DENEISDVP-SLAAYLQLSKLDWAYKTEPSTKACLGMQNNRCNWPRGRVLGGSSVLNYMLYVRGNRHDYDHWASLGNPGWDYDNVLRYFKKSEDNRNPYLANNKYHGRGGLLTVQESPWHSPLVAAFVEAGTQLGYDN-RDINGAKQAGFMIAQGTIRRGSRCSTAKAFLRPIRMRKNFHLSMNSHVTRVIIEPGTMRAQAVE-FVKHGKVYRIAARREVIISAGAINTPQLMMLSGLGPRKHLEKHGIRVLQDLP-VGENMQDHVGMGGLTFLVDKPVAI--VQDRFNPTAVTFQYVLRERGPMTTLGGVEGLAFVHTPYSNRSLDWPDIQFHMAPASINSDNGARVKKVLGLKESVYQEVYHPIANKDSWTIMPLLLRPRSRGSVKLRSANPFHYPLINANYFDDPLDAKTLVEGAKIALRVAEAQVFKQF-GSRLWRKPLPNCKQHKFLSDAYLECHVRTISMTIYHPCGTAKMGPAWDPEAVVDPRLRVYGVRGLRVIDASIMPTISSGNTNAPVIMIAEKGADLI 613          
BLAST of Choline dehydrogenase vs. Ensembl Fly
Match: CG9503 (gene:FBgn0030598 transcript:FBtr0073974)

HSP 1 Score: 298.901 bits (764), Expect = 4.337e-91
Identity = 202/565 (35.75%), Postives = 295/565 (52.21%), Query Frame = 2
Query:  320 DYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETKPQ----LHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHE---AGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFE--GKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIY-VRYQCKKPVTL----FSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLL-LDHGRQTMTSHS-----FQMFVSP-------------LRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMS----PG----PLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMI 1891
            D++++GAGSAG V+ANRL       V L+EAG  D+     +PL  G L    + +W ++T+P     L +   +   PRGKV+GGSS +N M+Y+RG  +DYD WE  G   WSY   L YFKK+E +         YH   G L V  +  +  L  ++V+AG + GY +  D NG +  GF     T  +G R S++KA+L P     +L ++ +S VT+++ +   K A GV+   K+ KL +V A KEV+L GG++NSP LL+LSGVG   EL KH + +++ +  VG+N QDH  +  + +   +PV++    F   S   +  V        T  G    L       + +++  PDI+FHF  G    D G Q   +H      ++    P             LR  S G+I L S +P ++P I PNY + + D+      +K+   +    A   + G  +S    PG    PL  TD   E  ++ Y+   YHP  TCKMG     D VVD++ RV G+  LRV+DAS+MP +VS NTNAP +MIAEK +DMI
Sbjct:   61 DFIVIGAGSAGAVVANRLTEVENWNVLLLEAGG-DETELTDVPLMAGYLQLS-KIDWQYKTEPSGTSCLAMQGGRCNWPRGKVLGGSSVLNYMLYLRGSKHDYDNWEAMGNPSWSYRDALYYFKKSEDNTNQYLANTPYHATGGYLTVGEAPYHTPLAASFVEAGVEMGYEN-RDLNGEKMTGFMIAQGTTRRGSRCSTSKAFLRPARLRPNLHISMNSHVTRIMIDPVTKLAFGVE-FVKDQKLYHVRATKEVVLSGGSVNSPQLLMLSGVGPRKELAKHRIPLIKEL-SVGENLQDHIGLGGLTFLVNQPVSIVENRFHTMSTVLQYAVFGQ--GPLTILGGVEGLAYVNTKYANSSLDWPDIEFHFVSGSTNSDGGSQLRKAHGLTDAFYRAVFEPINNRDAWSIIPMLLRPRSVGNIRLRSGNPFDYPYIFPNYLTDDFDMKTLIEGVKIAVALSRTKAMQRF-GSRISSIRWPGCEQVPLF-TDAFWECMVRRYTSTIYHPVGTCKMGPYWDKDAVVDAKLRVYGIRGLRVIDASIMPKLVSANTNAPVIMIAEKGSDMI 616          
BLAST of Choline dehydrogenase vs. Ensembl Fly
Match: CG9514 (gene:FBgn0030592 transcript:FBtr0073980)

HSP 1 Score: 295.819 bits (756), Expect = 6.354e-89
Identity = 193/571 (33.80%), Postives = 295/571 (51.66%), Query Frame = 2
Query:  296 ILQTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETKPQ----LHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHE----AGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFE--GKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTI-YVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSE-ANVTH--PDIQFHFFPG-LLLDHGRQTMTSHS------------------FQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMS-PGP-----LVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMI 1891
            + Q     D++I+G GSAG VLA+RL       + L+EAG  +   +  +PL L   +   + +W + T+PQ      +  ++    RGKV+GGSS +N M+Y+RG+  D+D+W   G  GWSY   LPYF+K+E       A    YHG  G   V  +  N  +   +++AG + GY    D NG +Q GFG +   + +G R S+AK++L P     +L V   S VTKV+ +   KRA GV+ + ++G+L+NV A +EVIL  GAI SPHL++LSG+G G EL +  + +V+H+PGVG+N QDH  +  + +    P+++   +       +     E      +++ L +  FI ++ AN +   PD+ F      ++ D G Q  T+H                   F +F   LR +S+G I L S +P  +P +  NY +   D+   +  +K    +    A   +     + P P      + TD     FI+ Y+   YH + T KMG       VVD Q RV G+  LRV+DAS+MP+I +GN +AP +MI EK ADMI
Sbjct:   88 VQQVDLAYDFIIIGGGSAGTVLASRLSEIPHWKILLLEAGGHETEIS-DVPL-LSLYLHKSKMDWKYRTQPQPTACQAMKDKRCCWTRGKVLGGSSVLNTMLYIRGNKRDFDQWADFGNPGWSYEDILPYFRKSEDQRNPYLARNKRYHGTGGLWTVQDAPYNTPIGPAFLQAGEEMGY-DIVDVNGEQQTGFGFYQFNMRRGSRSSTAKSFLRPARLRPNLHVALFSHVTKVLTDPHTKRATGVQFI-RDGRLQNVYATREVILSAGAIGSPHLMMLSGIGHGEELGRVGIPLVQHLPGVGQNLQDHIAVGGIAFLIDYPISIVMKRMVNINTALRYAITEDGP-LTSSIGLEAVAFINTKYANASDDWPDMNFMMTSASVMSDGGSQVKTAHGLTDEFYQEVFGEVNNRDVFGVFPMMLRPKSRGYIKLASKNPLRYPLLYHNYLTHPDDVNVLREGVKAAVAMGETQAMKRFGARYWNKPVPNCKHLTLYTDDYWNCFIRQYTMTIYHMSGTAKMGPPTDPWAVVDPQLRVYGIPGLRVIDASIMPAITNGNIHAPVVMIGEKGADMI 653          
BLAST of Choline dehydrogenase vs. Ensembl Zebrafish
Match: chdh (choline dehydrogenase [Source:ZFIN;Acc:ZDB-GENE-120111-1])

HSP 1 Score: 606.29 bits (1562), Expect = 0.000e+0
Identity = 285/547 (52.10%), Postives = 378/547 (69.10%), Query Frame = 2
Query:  323 YVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPK 1942
            YVIVGAGSAGCVLA+RL  +  ++V L+EAG  DK       +  I +P AL   +    +NW + T PQ H++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW+ +GA GW+Y  CLPYF+KA+ HE G + Y GG+GPLHV+R K    LH  +++AG QAGY + ED NGF+QEG G  DMTIHKG+RWS+A AYL P +   +L+     +VT+V+F+G RA GV+   + G+++ V A KEVIL GGAINSP LLLLSGVG+ +ELK   + +V+H+PGVG N QDH  +YV++ C +P+TL+  Q P    K+  +W    TGYGAT HL SGGFIRS  +V HPDIQFHF P  ++DHGR +    +FQ+ V P+RS S G + L S DP++HP + PNY S+E D+ EF+  ++LTREI AQ AFDE+RG E+ PGP VQ+D +++ F++  ++  YHP+ TCKMG       VV  + RV GVE LRVVDASVMPS+VSGN NAPT+MIAEK AD I G   L    VP++ P+
Sbjct:   37 YVIVGAGSAGCVLASRLTENPSDSVLLLEAGPKDKHLGSTRLSWKIHMPAALTYNLCDDRYNWFYHTLPQAHMDDRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWQSEGADGWNYDHCLPYFRKAQTHELGPDRYRGGDGPLHVSRGKTQNPLHYAFIQAGQQAGYPYTEDMNGFQQEGVGWMDMTIHKGQRWSTASAYLRPALSRPNLSTEVRCMVTRVLFDGARARGVE-YQQNGQIKKVFAEKEVILSGGAINSPQLLLLSGVGNADELKTLDIPVVQHLPGVGCNLQDHLELYVQHACTQPITLYRAQKPLQMLKIGLEWLLKFTGYGATAHLESGGFIRSRPDVPHPDIQFHFLPSQVIDHGRVSSKIEAFQVHVGPMRSTSVGWLKLKSKDPRDHPILQPNYLSTETDVLEFRECVRLTREIFAQQAFDEFRGPEVQPGPAVQSDAEIDAFVRQKADSAYHPSCTCKMGRPEDRMAVVSPELRVFGVEGLRVVDASVMPSMVSGNLNAPTIMIAEKAADAIKGLPSLHDPGVPVYQPR 582          
BLAST of Choline dehydrogenase vs. Ensembl Zebrafish
Match: chdh (choline dehydrogenase [Source:ZFIN;Acc:ZDB-GENE-120111-1])

HSP 1 Score: 605.905 bits (1561), Expect = 0.000e+0
Identity = 285/547 (52.10%), Postives = 378/547 (69.10%), Query Frame = 2
Query:  323 YVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPK 1942
            YVIVGAGSAGCVLA+RL  +  ++V L+EAG  DK       +  I +P AL   +    +NW + T PQ H++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW+ +GA GW+Y  CLPYF+KA+ HE G + Y GG+GPLHV+R K    LH  +++AG QAGY + ED NGF+QEG G  DMTIHKG+RWS+A AYL P +   +L+     +VT+V+F+G RA GV+   + G+++ V A KEVIL GGAINSP LLLLSGVG+ +ELK   + +V+H+PGVG N QDH  +YV++ C +P+TL+  Q P    K+  +W    TGYGAT HL SGGFIRS  +V HPDIQFHF P  ++DHGR +    +FQ+ V P+RS S G + L S DP++HP + PNY S+E D+ EF+  ++LTREI AQ AFDE+RG E+ PGP VQ+D +++ F++  ++  YHP+ TCKMG       VV  + RV GVE LRVVDASVMPS+VSGN NAPT+MIAEK AD I G   L    VP++ P+
Sbjct:   97 YVIVGAGSAGCVLASRLTENPSDSVLLLEAGPKDKHLGSTRLSWKIHMPAALTYNLCDDRYNWFYHTLPQAHMDDRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWQSEGADGWNYDHCLPYFRKAQTHELGPDRYRGGDGPLHVSRGKTQNPLHYAFIQAGQQAGYPYTEDMNGFQQEGVGWMDMTIHKGQRWSTASAYLRPALSRPNLSTEVRCMVTRVLFDGARARGVE-YQQNGQIKKVFAEKEVILSGGAINSPQLLLLSGVGNADELKTLDIPVVQHLPGVGCNLQDHLELYVQHACTQPITLYRAQKPLQMLKIGLEWLLKFTGYGATAHLESGGFIRSRPDVPHPDIQFHFLPSQVIDHGRVSSKIEAFQVHVGPMRSTSVGWLKLKSKDPRDHPILQPNYLSTETDVLEFRECVRLTREIFAQQAFDEFRGPEVQPGPAVQSDAEIDAFVRQKADSAYHPSCTCKMGRPEDRMAVVSPELRVFGVEGLRVVDASVMPSMVSGNLNAPTIMIAEKAADAIKGLPSLHDPGVPVYQPR 642          
BLAST of Choline dehydrogenase vs. Ensembl Mouse
Match: Chdh (choline dehydrogenase [Source:MGI Symbol;Acc:MGI:1860776])

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 276/558 (49.46%), Postives = 387/558 (69.35%), Query Frame = 2
Query:  308 KKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            K +  +V+VGAGSAGCVLA+RL  D  + V L+EAG  D           I +P AL   +   ++NW + T+PQ  ++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA GW Y+ CLPYF+KA++HE G N+Y GG+GPLHV+R K N  LH+ +++A  QAGY   ED NGF+QEGFG  DMT+H+G+RWS+A AYL PV+   +L     +LV++V+FEG RA+GV+ + K+G+      ++EVIL GGAINSP LL+LSGVG+ ++L+K  + +V H+PGVG+N QDH  +YV+  C +P+TL S Q P  K  +  +W    TG GAT HL +GGFIRS   V HPDIQFHF P  ++DHGR+     ++Q+ V  +R+ S G + L S +P++HP I PNY S+E D+ +F+  ++L+REI AQ A   +RG+E+ PG  VQ+DK+++ F++  ++  YHP+ TCKMG ++    VVD+Q +V+GVENLRVVDAS+MPS+VSGN NAPT+MIAEK AD+I G   L   NVP++ P+    QR
Sbjct:   40 KDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYNWYYHTEPQPGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLPYFRKAQRHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRVLFEGTRAVGVEYI-KDGQRHKAYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACTQPITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRKPTQQEAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFRGKELQPGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDKNVPVYKPQTLDTQR 596          
BLAST of Choline dehydrogenase vs. Ensembl Mouse
Match: Chdh (choline dehydrogenase [Source:MGI Symbol;Acc:MGI:1860776])

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 276/558 (49.46%), Postives = 387/558 (69.35%), Query Frame = 2
Query:  308 KKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            K +  +V+VGAGSAGCVLA+RL  D  + V L+EAG  D           I +P AL   +   ++NW + T+PQ  ++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA GW Y+ CLPYF+KA++HE G N+Y GG+GPLHV+R K N  LH+ +++A  QAGY   ED NGF+QEGFG  DMT+H+G+RWS+A AYL PV+   +L     +LV++V+FEG RA+GV+ + K+G+      ++EVIL GGAINSP LL+LSGVG+ ++L+K  + +V H+PGVG+N QDH  +YV+  C +P+TL S Q P  K  +  +W    TG GAT HL +GGFIRS   V HPDIQFHF P  ++DHGR+     ++Q+ V  +R+ S G + L S +P++HP I PNY S+E D+ +F+  ++L+REI AQ A   +RG+E+ PG  VQ+DK+++ F++  ++  YHP+ TCKMG ++    VVD+Q +V+GVENLRVVDAS+MPS+VSGN NAPT+MIAEK AD+I G   L   NVP++ P+    QR
Sbjct:   40 KDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYNWYYHTEPQPGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLPYFRKAQRHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRVLFEGTRAVGVEYI-KDGQRHKAYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACTQPITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRKPTQQEAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFRGKELQPGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDKNVPVYKPQTLDTQR 596          
BLAST of Choline dehydrogenase vs. UniProt/SwissProt
Match: sp|Q6UPE0|CHDH_RAT (Choline dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Chdh PE=1 SV=1)

HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0
Identity = 282/558 (50.54%), Postives = 386/558 (69.18%), Query Frame = 2
Query:  308 KKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            K +  +++VGAGSAGCVLANRL  D  + V L+EAG  D           I +P AL   +   ++NW + T+ Q  L+ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW +QGA GW Y+ CLPYF+KA+KHE G N+Y GG+GPLHV+R K N  LH+ +++A  QAGY   ED NGF+QEGFG  DMTIH+G+RWS+A AYL P +   +L     +LV++V+FEG RA+GV+ + K+G+      ++EVIL GGAINSP LL+LSGVG+ ++LKK  + +V H+PGVG+N QDH  IY+++ C +P+TL S Q P  K  +  +W    TG GAT HL +GGFIRS   V HPDIQFHF P  ++DHGR+     ++Q+ V  +R+ S G + L S +P++HP I+PNY S+E D+ +F+  +KLTREI AQ AF  +RG+E+ PG  VQ+DK+++ F++  ++  YHP+ TCKMG  +    VVD Q RV+GVENLRV+DAS+MPS+VSGN NAPT+MIAEK AD+I G   L   NVP++ P+    QR
Sbjct:   43 KDEYTFIVVGAGSAGCVLANRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVANLCDDKYNWYYHTEAQPGLDGRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHRQGAEGWDYAHCLPYFRKAQKHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTIHQGKRWSTASAYLRPALSRPNLRAEVQTLVSRVLFEGTRAVGVEYI-KDGQSHKAYVSREVILSGGAINSPQLLMLSGVGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQHACTQPITLHSAQKPLRKVCIGLEWLWRFTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRKPTQQEAYQVHVGTMRATSVGWLKLRSTNPQDHPMINPNYLSTETDVEDFRQCVKLTREIFAQEAFAPFRGKELQPGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDQQTRVIGVENLRVIDASIMPSVVSGNLNAPTIMIAEKAADVIKGCPALGDENVPVYKPQTLDTQR 599          
BLAST of Choline dehydrogenase vs. UniProt/SwissProt
Match: sp|Q8BJ64|CHDH_MOUSE (Choline dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Chdh PE=1 SV=1)

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 276/558 (49.46%), Postives = 387/558 (69.35%), Query Frame = 2
Query:  308 KKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            K +  +V+VGAGSAGCVLA+RL  D  + V L+EAG  D           I +P AL   +   ++NW + T+PQ  ++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA GW Y+ CLPYF+KA++HE G N+Y GG+GPLHV+R K N  LH+ +++A  QAGY   ED NGF+QEGFG  DMT+H+G+RWS+A AYL PV+   +L     +LV++V+FEG RA+GV+ + K+G+      ++EVIL GGAINSP LL+LSGVG+ ++L+K  + +V H+PGVG+N QDH  +YV+  C +P+TL S Q P  K  +  +W    TG GAT HL +GGFIRS   V HPDIQFHF P  ++DHGR+     ++Q+ V  +R+ S G + L S +P++HP I PNY S+E D+ +F+  ++L+REI AQ A   +RG+E+ PG  VQ+DK+++ F++  ++  YHP+ TCKMG ++    VVD+Q +V+GVENLRVVDAS+MPS+VSGN NAPT+MIAEK AD+I G   L   NVP++ P+    QR
Sbjct:   40 KDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYNWYYHTEPQPGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLPYFRKAQRHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRVLFEGTRAVGVEYI-KDGQRHKAYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACTQPITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRKPTQQEAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFRGKELQPGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDKNVPVYKPQTLDTQR 596          
BLAST of Choline dehydrogenase vs. UniProt/SwissProt
Match: sp|Q8NE62|CHDH_HUMAN (Choline dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=CHDH PE=1 SV=2)

HSP 1 Score: 593.193 bits (1528), Expect = 0.000e+0
Identity = 280/560 (50.00%), Postives = 383/560 (68.39%), Query Frame = 2
Query:  302 QTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            +++ +  YV+VGAGSAGCVLA RL  D    V L+EAG  D        +  I +P AL   +    +NWC+ T+ Q  L+ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW++QGA GW Y+ CLPYF+KA+ HE G + Y G +GPL V+R K N  LH  +++A  QAGY   ED NGF+QEGFG  DMTIH+G+RWS+A AYL P +   +L    ++LV++V+FEG RA+GV+ + K G+     A+KEVIL GGAINSP LL+LSG+G+ ++LKK  + +V H+PGVG+N QDH  IY++  C +P+TL S Q P  K  +  +W    TG GAT HL +GGFIRS+  V HPDIQFHF P  ++DHGR      ++Q+ V P+R  S G + L S +P++HP I PNY S+E DI +F+  +KLTREI AQ A   +RG+E+ PG  +Q+DK+++ F++  ++  YHP+ TCKMG  +    VVD Q RV+GVENLRVVDAS+MPS+VSGN NAPT+MIAEK AD+I G+  L   +VP++ P+  + QR
Sbjct:   36 ESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQGHELGASRYRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRWSAACAYLHPALSRTNLKAEAETLVSRVLFEGTRAVGVEYV-KNGQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTRPITLHSAQKPLRKVCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDHGRVPTQQEAYQVHVGPMRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRGKELQPGSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPALWDKDVPVYKPRTLATQR 594          
BLAST of Choline dehydrogenase vs. UniProt/SwissProt
Match: sp|A6X2G7|BETA_OCHA4 (Oxygen-dependent choline dehydrogenase OS=Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / JCM 21032 / NBRC 15819 / NCTC 12168) OX=439375 GN=betA PE=3 SV=1)

HSP 1 Score: 528.48 bits (1360), Expect = 9.582e-180
Identity = 248/548 (45.26%), Postives = 354/548 (64.60%), Query Frame = 2
Query:  314 DTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQ 1957
            + D+VI+G+GSAG  +A RL  DG+ +V ++E G  D    IQ+P AL   M    ++W F T+P+ H+  R +  PRGKV+GGSSSINGM+Y+RGH  DYD W + GA GW+Y+  LPYFK+ E    G+  + G NGPL++ R K +  L   +V+AG +AG+   ED+NG +QEGFG  + TIH G RWS+A AYL P +K  ++ +    L  K++ EGKRA+GV++         + A +EVI+   +INSP LL+LSG+G   +LK+H + +V   PGVG+N QDH  +Y++ +C +P+TL+S  +   K K+  +W   KTG GAT H  S  F+RS+A V +PDIQ+HF P  +   G+    SH FQ  V P+RS+S+GS++L S +P+E P I  NY S E D  +F+  ++LTREI  Q+AF+ YRG E+ PG  VQ+D +++ FIK + E  +HP  TCKMGA +    VVD++CRV+GVE LRV D+S+ P I +GN N P++M+ EK +D ILG+ PL + +   W   NP  Q
Sbjct:    2 EADFVIIGSGSAGSAMAYRLSEDGRYSVIVIEYGVPDVGPLIQMPAALSFPMNMETYDWGFSTEPEPHIGGRSLVTPRGKVLGGSSSINGMVYVRGHARDYDHWSESGARGWAYADVLPYFKRMENSSGGQEGWRGTNGPLYIQRGKRDNPLFHAFVEAGHEAGFEVTEDYNGEKQEGFGPMEQTIHNGRRWSAANAYLKPALKRPNVKLVK-GLARKIVLEGKRAVGVEIEAGR-SFSTIRARREVIIAASSINSPKLLMLSGIGPAAQLKEHGIEVVADRPGVGQNLQDHLEVYIQQECTQPITLYSKLNLFSKAKIGAEWLFFKTGDGATNHFESAAFLRSKAGVEYPDIQYHFLPVAIRYDGKAAAQSHGFQAHVGPMRSKSRGSVTLRSANPREKPVIKFNYMSHEDDWADFRHCVRLTREIFGQAAFNPYRGAEIQPGAHVQSDDEIDNFIKEHVESAFHPCGTCKMGAVDDPMAVVDAECRVIGVEGLRVADSSIFPRITNGNLNGPSIMVGEKASDHILGRTPLARSDQEPWI--NPRWQ 545          
BLAST of Choline dehydrogenase vs. UniProt/SwissProt
Match: sp|A9M9H8|BETA_BRUC2 (Oxygen-dependent choline dehydrogenase OS=Brucella canis (strain ATCC 23365 / NCTC 10854) OX=483179 GN=betA PE=3 SV=1)

HSP 1 Score: 527.709 bits (1358), Expect = 1.612e-179
Identity = 248/548 (45.26%), Postives = 354/548 (64.60%), Query Frame = 2
Query:  314 DTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQ 1957
            + D+VI+G+GSAG  +A RL  DG+ +V ++E G  D    IQ+P AL   M    ++W F ++P+ H+  R +  PRGKV+GGSSSINGM+Y+RGH  D+D W + GA GW+Y+  LPYFK+ E  + G+  + G NGPL+V R K +  L   +V+AG QAG+  A+D+NG +QEGFG  + TIH G RWS+A AYL P +K  ++ +       K++ EGKRA+GV++         + A +EVI+   +INSP LL+LSG+G    LK+H +++V   PGVG+N QDH  +Y++ +C +P+TL+S  +   K ++  +W   KTG GAT H  S  F+RS+A V +PDIQ+HF P  +   G+    SH FQ  V P+RS+S+GS++L S +P+E P I  NY S E D  +F+  ++LTREI  Q+AFD YRG E+ PG  VQTD +++ FI+ + E  +HP  TCKMGA +    VVD +CRV+GVE LRV D+S+ P I +GN N P++M+ EK +D ILG+ PL + N   W   NP  Q
Sbjct:    2 EADFVIIGSGSAGSAMAYRLSEDGRYSVIVIEYGVPDVGPLIQMPAALSFPMNMETYDWGFSSEPEPHIGGRSLVTPRGKVLGGSSSINGMVYVRGHACDFDHWSQSGARGWAYADVLPYFKRMENSQGGQEGWRGTNGPLYVQRGKRDNPLFHAFVEAGHQAGFEVADDYNGEKQEGFGPMEQTIHNGRRWSAANAYLKPALKRPNVKLVK-GFARKIVLEGKRAVGVEIEAGR-TFSTIRARREVIIAASSINSPKLLMLSGIGPAAHLKEHGIDLVADRPGVGQNLQDHLEVYIQQECTQPITLYSELNLFSKARIGVEWLLFKTGDGATNHFESAAFVRSKAGVEYPDIQYHFLPVAIRYDGKAAAQSHGFQAHVGPMRSKSRGSVTLRSANPREKPVIKFNYMSHEDDWADFRHCVRLTREIFGQAAFDPYRGAEIQPGAHVQTDDEIDNFIREHVESAFHPCGTCKMGAVDDPMAVVDPECRVIGVEGLRVADSSIFPRITNGNLNGPSIMVGEKASDHILGRTPLARSNQEPWI--NPRWQ 545          
BLAST of Choline dehydrogenase vs. TrEMBL
Match: A0A091REX2 (Choline dehydrogenase OS=Merops nubicus OX=57421 GN=N331_07064 PE=3 SV=1)

HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 304/591 (51.44%), Postives = 410/591 (69.37%), Query Frame = 2
Query:  215 GYTLKSKIFDKNISVQNSQIRSLHLCRILQTKKDT--DYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            G   K+ I    + + + Q++       L ++K +  +YVIVGAGSAGCVLANRL  D  +TV L+EAG  D           I +P AL   +   ++NW + T  Q H++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA GW Y  CLPYFKKA+ HE G +LY GGNGPLHV+R K N  LH+ +++A  QAGY   +D NG++QEGFG  DMT+H+G+RWS+A AYL P M   +L+V   +LVTK++F+G ++IGV+ + K G+ + V A+KEVIL GGAINSP LL+LSG+G+ ++LKK  + +V H+PGVG+N QDH  +YV+ +C KP+TL++ Q P    ++  +W    TG GAT HL SGGFIRSE  V HPDIQFHF P  ++DHGR   T  ++Q+ V P+RS S G + L S DP++HP I+PNY S+ERDICEF+  +KLTREI AQ AF+++RG E+ PG  VQ+DK ++ FI+  ++  YHP+ TCKMG  + +  VVD Q +V+GVENLRVVDASVMPSIVSGN NAPT+MIAEK AD+I G   L + NVP++ PK    QR
Sbjct:    6 GTLFKAHILKNILGINDQQLKISRTSSHLSSEKASSYNYVIVGAGSAGCVLANRLTEDPHSTVLLLEAGPKDTLLGSKRLMWKIHMPAALTYNLCNEKYNWYYHTTSQKHMDNRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWSREGAVGWDYEHCLPYFKKAQTHELGPDLYRGGNGPLHVSRGKTNHPLHQAFLEATQQAGYPFTDDMNGYQQEGFGWMDMTVHEGQRWSTASAYLRPAMSRPNLSVAEKTLVTKILFQGTKSIGVEYV-KNGQKKKVFASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEVYVQQKCTKPITLYNAQKPVNMVRIGLEWLWKFTGEGATAHLESGGFIRSEPGVPHPDIQFHFLPSQVIDHGRVPSTMEAYQVHVGPMRSTSVGWLKLKSTDPRDHPIIEPNYLSTERDICEFRQCVKLTREIFAQKAFEKFRGPEIQPGNHVQSDKDIDAFIRQKADSAYHPSCTCKMGQFSDSTAVVDPQTKVIGVENLRVVDASVMPSIVSGNLNAPTIMIAEKAADIIKGLPLLQEKNVPVYKPKTLETQR 595          
BLAST of Choline dehydrogenase vs. TrEMBL
Match: A0A091MUR4 (Choline dehydrogenase OS=Acanthisitta chloris OX=57068 GN=N310_12240 PE=3 SV=1)

HSP 1 Score: 629.402 bits (1622), Expect = 0.000e+0
Identity = 305/596 (51.17%), Postives = 409/596 (68.62%), Query Frame = 2
Query:  209 FRGYTLKSKIFDKN-----ISVQNSQIRSLHLCRILQTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            F+ +TLK+ I   N     IS  +SQ+ S       +     +YVIVGAGSAGCVLANRL  D  +TV L+EAG  D           I +P AL   +   ++NW + T  Q H++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA+GW Y  CLPYFKKA+ HE G N Y GGNGPLHV+R K N  LH+ +++A  QAGY   +D NG++QEGFG  DMT+H+G+RWS+A AYL P M   +L+V   +LVTK++F+G + IGV+ + K G+ + V ANKE+IL GGAINSP LL+LSG+G+ ++LK   + +V H+PGVG+N QDH  +YV+ +C KP+TL++ Q P    ++  +W    TG GAT HL SGGFIRSE  V HPDIQFHF P  ++DHGR   T  ++Q+ V P+RS S GS+ L S DP +HP I+PNY S+ERDI EF+  +KLTREI AQ AF+ +RG E+ PG  VQ+DK+++ FI+  ++  YHP+ TCKMG  + +  VVD Q +V+G+ENLRVVDAS+MPSIV+GN NAPT+MIAEK AD+I G   L + NVP++ PK    QR
Sbjct:    9 FKAHTLKN-ILGINEQQFKISRASSQLSS-------EKANSYNYVIVGAGSAGCVLANRLTEDPLSTVLLLEAGPKDTLLGSKRLMWKIHMPAALTYNLCDEKYNWYYHTTAQKHMDNRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWSREGATGWDYEHCLPYFKKAQTHELGPNQYRGGNGPLHVSRGKTNHPLHQAFLEATQQAGYPFTDDMNGYQQEGFGWMDMTVHQGQRWSTASAYLRPAMSRPNLSVAEKTLVTKILFQGTKCIGVEYV-KNGQRKKVFANKEIILSGGAINSPQLLMLSGIGNADDLKNLGIPVVCHLPGVGQNLQDHLEVYVQQKCTKPITLYTAQKPLNMVRIGLEWLWKFTGEGATAHLESGGFIRSEPGVPHPDIQFHFLPSQVIDHGRVASTMEAYQVHVGPMRSTSVGSVKLKSTDPNDHPIIEPNYMSTERDIWEFRQCVKLTREIFAQKAFENFRGPEIQPGNHVQSDKEIDAFIRQKADSAYHPSCTCKMGQHSDSTAVVDPQTKVIGIENLRVVDASIMPSIVTGNLNAPTIMIAEKAADIIKGLPSLQEKNVPVYKPKTLETQR 595          
BLAST of Choline dehydrogenase vs. TrEMBL
Match: A0A091PFX1 (Choline dehydrogenase OS=Leptosomus discolor OX=188344 GN=N330_04833 PE=3 SV=1)

HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0
Identity = 299/591 (50.59%), Postives = 405/591 (68.53%), Query Frame = 2
Query:  215 GYTLKSKIFDKNISVQNSQIRSLHLCRILQTKKDT--DYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            G   +S I    + +   Q +       L ++K    +YVIVGAGSAGCVLANRL  D  +TV L+EAG  D           I +P AL   +   ++NW + T  Q H++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA+GW Y  CLPYFKKA+ HE G + Y GGNGPLHV+R K N  LH  +++A  QAGY   +D NG++QEGFG  DMT+H+G+RWS+A AYL P +   +L+V   +LVTK++F+G ++IGV+ +T  G+ +   A+KEVIL GGAINSP LL+LSG+G+ +ELKK  + +V H+PGVG+N QDH  +YV+ +C +P+TL++ Q P    K+  +W    TG GAT HL SGGFIRSE  V HPDIQFHF P  ++DHGR   T  ++Q+ V P+RS S G + L S DP +HP I+PNY S+ERDI EF+  +KLTREI AQ AF+++RG E+ PG  +Q+DK+++ FI+  ++  YHP+ TCKMG  + +  VVD Q +V+GVENLRVVDAS+MPS+VSGN NAPT+MIAEKVAD+I G   L + NVP++ PK    QR
Sbjct:    6 GTLFRSHILKNTLGINEQQFKISRTSSQLSSEKTNSYNYVIVGAGSAGCVLANRLTEDPLSTVLLLEAGPKDTLLGSKRLMWKIHMPAALTHNLCDEKYNWYYHTTSQKHMDNRIMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWSREGATGWDYEHCLPYFKKAQTHELGPDQYRGGNGPLHVSRGKTNHPLHHAFLEAAQQAGYPFTDDMNGYQQEGFGWMDMTVHQGQRWSTASAYLHPAISRPNLSVAEKTLVTKILFQGTKSIGVEYVTN-GQRKKAFASKEVILSGGAINSPQLLMLSGIGNADELKKLGIPVVCHLPGVGQNLQDHLEVYVQQKCTQPITLYNAQKPVNMVKIGLEWLWKFTGEGATAHLESGGFIRSEPGVPHPDIQFHFLPSQVIDHGRVASTMEAYQVHVGPMRSTSVGWLKLKSTDPNDHPIIEPNYLSTERDIWEFRQCVKLTREIFAQKAFEKFRGPEIQPGNHIQSDKEIDAFIRQKADSAYHPSCTCKMGQLSDSTAVVDPQTKVIGVENLRVVDASIMPSVVSGNLNAPTIMIAEKVADIIKGLPSLQEKNVPVYKPKTLETQR 595          
BLAST of Choline dehydrogenase vs. TrEMBL
Match: A0A091EN48 (Choline dehydrogenase OS=Corvus brachyrhynchos OX=85066 GN=N302_10150 PE=3 SV=1)

HSP 1 Score: 627.861 bits (1618), Expect = 0.000e+0
Identity = 301/593 (50.76%), Postives = 409/593 (68.97%), Query Frame = 2
Query:  209 FRGYTLKSKIFDKNISVQNSQIRSLHLCRILQTKKDT--DYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTD----KNR---TIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            F+ +TLK+ +      V   Q +       L ++K    +Y+IVGAGSAGCVLANRL  D ++TV L+EAG  D      R    I +P AL   +   ++NW + T PQ H++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA GW Y  CLPYFKKA+ HE G + Y GGNGPLHV+R K N  LH+ +++A  QAGY   +D NG++QEGFG  DMTIH+G+RWS+A AYL P +   + +V   +LVTK++F+G + IGV+ + K G+ + V ANK+VIL GGAINSP LL+LSG+G+ ++LKK  + +V H+PGVG+N QDH  +YV+ +C KP+TL+S Q P    ++  +W    TG GAT HL SGGFIRSE  V HPDIQFHF P  ++DHGR   T  ++Q+ V P+RS S G + L S DP +HP ++PNY S+ERDI EF+  +KLTREI AQ AF+++RG E+ PG  VQ+DK+++ FI+  ++  YHP+ TCKMG  + +  VVD Q +V+GVENLRVVDAS+MPS+V+GN NAPT+MIAEK AD+I G   L + NVP++ PK    QR
Sbjct:    9 FKAHTLKNML-----GVNEQQFKISRASSQLSSEKANSYNYIIVGAGSAGCVLANRLTEDSQSTVLLLEAGPKDTLLGSKRLLWKIHMPAALTYNLCDEKYNWYYHTTPQRHMDNRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWSREGALGWDYEHCLPYFKKAQTHELGPDQYRGGNGPLHVSRGKTNHPLHQAFLEAAQQAGYPFTDDMNGYQQEGFGWMDMTIHQGQRWSTASAYLRPAISRPNFSVAEKTLVTKILFQGTKCIGVEYV-KNGQRKKVFANKDVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEVYVQQKCTKPITLYSAQKPINMVRIGLEWLWKFTGEGATAHLESGGFIRSEPGVPHPDIQFHFLPSQVIDHGRVASTMEAYQVHVGPMRSTSVGWLKLKSSDPNDHPILEPNYLSTERDIWEFRQCVKLTREIFAQKAFEKFRGPEIQPGNHVQSDKEIDAFIRQKADSAYHPSCTCKMGQPSDSTAVVDPQTKVIGVENLRVVDASIMPSVVTGNLNAPTIMIAEKAADIIKGLPSLQEKNVPVYKPKTLETQR 595          
BLAST of Choline dehydrogenase vs. TrEMBL
Match: A0A3M0JI14 (Choline dehydrogenase OS=Hirundo rustica rustica OX=333673 GN=DUI87_23369 PE=3 SV=1)

HSP 1 Score: 627.861 bits (1618), Expect = 0.000e+0
Identity = 308/628 (49.04%), Postives = 417/628 (66.40%), Query Frame = 2
Query:  143 FIQNSRQFSIASNKL---ISANQNGFR----------GYTLKSKIFDKNISVQNSQIRSLHLCRILQTKKDT--DYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            F++NS     AS+KL   +S    GF+          G   K       + +   Q +       L ++K    +Y+IVGAGSAGCVLANRL  D ++TV L+EAG  D           I +P AL   +   ++NW + T PQ H++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW  QGA GW Y  CLPYFKKA+ HE G + Y GGNGPLHV+R K    LH+ +++A  QAGY   +D NG++QEGFG  DMTIH+G+RWS+A AYL P +   + +V   +LVTK++F+G + IGV+ + K G+ + V ANKEVIL GGAINSP LL+LSG+G+ ++LKK  + +V H+PGVG+N QDH  +YV+ +C KP+TL+S Q P    ++  +W    TG GAT HL SGGFIRSE  V HPDIQFHF P  ++DHGR   T+ ++Q+ V P+RS S G + L S DP +HP I+PNY S+ERDI EF+  +KLTREI AQ AF+++RG E+ PG  VQ+DK+++ F++  ++  YHP+ TCKMG  + +  VVD Q +V+GVENLRVVDAS+MPS+V+GN NAPT+MIAEK AD+I G   L + NVP++ PK    QR
Sbjct:  538 FVRNS-----ASDKLSVKMSYLMKGFKCHSPAMCKVAGSLFKVHTLRNTLGINERQFKISRASSQLSSEKANSYNYIIVGAGSAGCVLANRLTEDPQSTVLLLEAGPKDTLLGSKRLMWKIHMPAALTYNLCDEKYNWYYHTTPQRHMDNRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWSSQGAPGWDYEHCLPYFKKAQTHELGPDQYRGGNGPLHVSRGKTKHPLHQAFLEAAQQAGYPFTDDMNGYQQEGFGWMDMTIHRGQRWSTASAYLRPAISRPNFSVAEKTLVTKILFQGTKCIGVEYV-KNGQKKKVFANKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEVYVQQKCTKPITLYSAQKPLNMVRIGLEWLWKFTGEGATAHLESGGFIRSEPGVPHPDIQFHFLPSQVIDHGRVASTTEAYQVHVGPMRSTSVGWLKLKSSDPNDHPIIEPNYLSTERDIWEFRQCVKLTREIFAQKAFEKFRGPEIRPGDHVQSDKEIDAFVRQKADSAYHPSCTCKMGQPSDSTAVVDPQTKVIGVENLRVVDASIMPSVVTGNLNAPTIMIAEKAADIIKGLPSLQEKNVPVYKPKTLETQR 1159          
BLAST of Choline dehydrogenase vs. Ensembl Cavefish
Match: chdh (choline dehydrogenase [Source:NCBI gene;Acc:103039657])

HSP 1 Score: 585.489 bits (1508), Expect = 0.000e+0
Identity = 282/578 (48.79%), Postives = 383/578 (66.26%), Query Frame = 2
Query:  254 SVQNSQIRSLHLCRILQTKKDTD--YVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            S  N Q R  H   +  + K+    YVIVGAGSAGCVLANRL  +   +V L+EAG  D        +  I +P AL   +   ++NW + T PQ  ++ R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA GW Y  CLPYF+KA+ HE G + Y GG+GPLHV+R K +  LH  +++A  QAGY   +D NG++QEG G  DMTI+KG+RWS+A AYL P +   +L      L T V+F+G RA+GV+   + G+ + V+A+KEVIL GGAINSP LL+LSGVG+ + L+K  + +V+H+PGVG N QDH  +YV+ QC +P+TL+  Q P    K+  +W    TGYGAT HL SGGFIR   +VTHPDIQFHF P  ++DHGR      ++Q+ V P+RS S G + L S +P +HP + PNY S++ D+ EF+  +KL+REI AQ AFD +RG E  PGP VQ+D +++ F++  ++  YHP+ TCKMG ++    VVD Q RV G+E LRVVDAS+MPS+VSGN NAPT+MIAEK AD I G   L   +V ++ P +   QR
Sbjct:   27 SCLNPQHRHRHYSTVSASPKNPSFSYVIVGAGSAGCVLANRLSENSSESVLLLEAGPKDMVLGSRRLSWKIHMPAALTYNLCDDKYNWYYNTLPQDGMDGRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYDHCLPYFRKAQTHELGADRYRGGSGPLHVSRGKTDHPLHHAFIEASQQAGYPFTDDMNGYQQEGVGWMDMTIYKGKRWSTASAYLRPALSRPNLKAEVGCLTTHVLFDGTRAVGVE-YQQNGQTKKVLADKEVILSGGAINSPQLLMLSGVGNADYLQKLDIPVVQHLPGVGSNLQDHLELYVQQQCTQPITLYKAQKPFHMIKIGLEWMLKFTGYGATAHLESGGFIRGRPHVTHPDIQFHFLPSQVIDHGRVNSKIEAYQVHVGPIRSTSVGWLKLKSKNPHDHPLLQPNYLSTDIDVWEFRQCVKLSREIFAQKAFDPFRGPEAQPGPAVQSDAEIDAFVRQKADSAYHPSCTCKMGRSSDPMAVVDPQTRVYGLEGLRVVDASIMPSVVSGNLNAPTIMIAEKAADAIKGLPSLHDPDVLVYQPASLETQR 603          
BLAST of Choline dehydrogenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002402.1 (pep scaffold:Pmarinus_7.0:GL482915:11564:16540:1 gene:ENSPMAG00000002188.1 transcript:ENSPMAT00000002402.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 322.013 bits (824), Expect = 3.466e-104
Identity = 158/335 (47.16%), Postives = 221/335 (65.97%), Query Frame = 2
Query:  320 DYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQ-GASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTG 1300
             +V+VGAGSAGCV+A RL  D  + V L+EAG  D           I +P  L +++   ++   + T+PQ HL  R +  PRG+V GG+SS+NGMIY+RGH  DYD WE++ GASGWSY++CLPYF++A+ H  G + Y GG+GPL V+R      LH  +++A +QAG+   ED NGFRQEGFG +D+TIH+G+RWSSA AYL P +   +L V   ++ T+V+F G+RA+GV+VL + G  E V A +EVILCGGAINSP LLLLSG+G    LK+  + ++ + PGVG+N QDH  + V+ +C +P+T ++ Q P    +    W    TG
Sbjct:    9 SHVVVGAGSAGCVMAGRLSEDAASRVLLLEAGPRDTVLGSKRLAWHIHMPAGLSKVLHNSKYAVHYYTEPQEHLGGRSLLWPRGRVWGGTSSMNGMIYIRGHALDYDGWEQEHGASGWSYANCLPYFRRAQSHALGPDEYRGGDGPLRVSRVPTQSPLHVAFLEAASQAGHALNEDMNGFRQEGFGWYDLTIHQGKRWSSACAYLHPALSRPNLEVRDGAVATRVLFRGERAVGVEVL-RGGVKEQVFAEREVILCGGAINSPQLLLLSGIGPEKHLKQVGIPVLVNSPGVGRNLQDHLNVSVKQRCAQPLTAYTAQKPHNMIRTGLAWMLTSTG 342          
BLAST of Choline dehydrogenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007537.1 (pep scaffold:Pmarinus_7.0:GL493288:965:4963:-1 gene:ENSPMAG00000006807.1 transcript:ENSPMAT00000007537.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 122.479 bits (306), Expect = 4.982e-33
Identity = 58/127 (45.67%), Postives = 75/127 (59.06%), Query Frame = 2
Query: 1163 GVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSS 1543
            GVG N QDH  +YV+ +C +PVTL+ L  P+        W    TG  AT H+ +GGF RSE +V HPD+QFHF P  ++DHGR   T  +FQ  V  LR  S G + L S +P + P I PNY S+
Sbjct:    1 GVGMNLQDHLEVYVQQRCLQPVTLYGLLRPDRTLSAGLQWLLRFTGPCATAHMDTGGFARSEPSVAHPDVQFHFLPAQVIDHGRVDPTMEAFQAHVGSLRPTSVGWLKLRSANPTDPPVIQPNYLST 127          
BLAST of Choline dehydrogenase vs. Ensembl Nematostella
Match: EDO38956 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBJ6])

HSP 1 Score: 370.933 bits (951), Expect = 1.596e-122
Identity = 173/357 (48.46%), Postives = 249/357 (69.75%), Query Frame = 2
Query:  884 RWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSK 1954
            RW++A AYL P ++  +L   T +L+T+V+FEG +A+GV+    + ++  V A KEVI+ GGAINSP LL+LSGVG+  EL +  + +V ++PGVG+N QDH  +Y++ +CKKP+TL+S Q       +   W   +TG GA+ HL +GGFIRS   V HPDIQFHF P  ++DHGR  +  H++Q+ V  +RS+SKG + L S +  +HP ID NY S+E D  E ++ ++L+REI AQ AF+ +RG+EM PG  ++TD +++ F++ +++  YHP+ TCKMG+ +    VVD+  RV  V+NLRVVDAS+MPS+VSGN NAPT+MIAEK+AD ILGK PLP+   P++  K P K
Sbjct:    3 RWNTANAYLRPAIQRTNLQADTRALITRVLFEGNKAVGVE-YHADNQIRRVRAKKEVIISGGAINSPQLLMLSGVGNAEELTRLGIPVVVNLPGVGENLQDHLEMYIQQECKKPLTLYSAQKLMNMIPIGIRWFLFQTGLGASAHLEAGGFIRSREGVPHPDIQFHFLPSGVIDHGRTPIDRHAYQLHVGSMRSQSKGYVKLKSPNAYDHPIIDFNYMSTEDDWQEMRACVRLSREIFAQKAFEPFRGDEMRPGSHIRTDDEIDAFVREFADSAYHPSCTCKMGSASDPLAVVDNAARVFHVDNLRVVDASIMPSVVSGNLNAPTVMIAEKIADAILGKDPLPRSKAPVF--KTPEK 356          
BLAST of Choline dehydrogenase vs. Ensembl Nematostella
Match: EDO38958 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBK1])

HSP 1 Score: 276.559 bits (706), Expect = 4.621e-84
Identity = 127/256 (49.61%), Postives = 169/256 (66.02%), Query Frame = 2
Query:  320 DYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPH 1087
            DYVI GAGSAGCVLANRL AD  + V L+EAG  D+   I +P AL   +   ++NW + T PQ H+N R ++ PRG+V GGSSS+N M+Y+RGH YDYDRWE++GA GWSY+ CLPYF+K++ HE G + Y GG+GPLHV+R K N  L   +++   QAGY   ED NG++QEG G   MTIHKG RW++A AYL P ++  +L   T +L+T+V+FEG +A+GV+          V     +  C G    PH
Sbjct:   14 DYVICGAGSAGCVLANRLSADPDSKVLLLEAGPKDRTWKIHMPAALIYNLCDDKYNWYYHTAPQKHMNNRVMYCPRGRVWGGSSSLNAMVYIRGHAYDYDRWEREGAQGWSYADCLPYFRKSQTHELGADDYRGGDGPLHVSRGKTNNPLFHAFLEGAQQAGYPFTEDMNGYQQEGVGWMAMTIHKGIRWNTANAYLRPAIQRTNLHADTRALITRVLFEGNKAVGVEYHAD----NQVGLLARISYCAGGYPHPH 265          

HSP 2 Score: 103.219 bits (256), Expect = 5.385e-23
Identity = 49/82 (59.76%), Postives = 62/82 (75.61%), Query Frame = 2
Query: 1709 HPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSK 1954
            +P+ TCKMG+ +    VVD+  RV  V+NLRVVDAS+MPS+VSGN NAPT+MIAEK+AD ILGK PLP+   P++  K P K
Sbjct:  455 YPSCTCKMGSASDPLAVVDNAARVFHVDNLRVVDASIMPSVVSGNLNAPTVMIAEKIADAILGKDPLPRSKAPVF--KTPEK 534          
BLAST of Choline dehydrogenase vs. Ensembl Medaka
Match: chdh (choline dehydrogenase [Source:NCBI gene;Acc:101161152])

HSP 1 Score: 612.068 bits (1577), Expect = 0.000e+0
Identity = 286/560 (51.07%), Postives = 385/560 (68.75%), Query Frame = 2
Query:  302 QTKKDTDYVIVGAGSAGCVLANRLLADGKNTVHLMEAGSTDK-------NRTIQIPLALGELMGGHEFNWCFETKPQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQR 1960
            Q      YV+VGAGSAGCVLANRL  D   +V L+EAG  D        +  I +P AL   +   ++NW + T PQ H+N R ++ PRG+V GGSSS+N M+Y+RGH  DY+RW ++GA+GW Y  CLPYF+KA+ HE GEN Y GG GPLHV+R K N  LH+ +++AG QAGY   +D NG++QEG G  DMTI+KG+RWS+A AYL PV+   +L      + T+++F+G RA+GV+  T+ G+ + V A KEVIL GGAINSP LL+LSGVG+ ++LK+  + +V+H+PGVG N QDH  +YV+ QC +P+TL+  Q P    K+  +W    TGYGAT HL SGGFIRS  NVTHPDIQFHF P  ++DHGR      ++Q+ V P+RS S G I L S +P +HP + PNY S++ D+ EF+  +KL+REI AQ AFD +RG E+ PGP VQ+D +++ F++  ++  YHP+ TCKMG+ +    VV +  RV+G++ LRVVDAS+MPSIVSGN NAPT+MIAEK AD+I G+ PL    VP++ P     QR
Sbjct:   69 QRTPSFSYVVVGAGSAGCVLANRLTEDAHESVLLLEAGPKDLWLGSLRLSWKIHMPAALTYNLCDDKYNWYYHTLPQAHMNNRALYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAAGWDYQHCLPYFRKAQCHELGENRYRGGRGPLHVSRGKTNHPLHKAFIEAGRQAGYPFTDDMNGYQQEGLGWMDMTIYKGKRWSTASAYLRPVLSRPNLKTEVRCVATRILFDGGRAVGVE-YTQNGQKKKVFAEKEVILSGGAINSPQLLMLSGVGNADDLKELGIPVVQHLPGVGSNLQDHLELYVQQQCTQPITLYKAQKPFHMVKIGLEWLSVFTGYGATAHLESGGFIRSRPNVTHPDIQFHFLPSQVIDHGRIASKIEAYQVHVGPMRSTSIGWIKLKSPNPLDHPVLQPNYLSTDIDVWEFRQCVKLSREIFAQKAFDPFRGPEVQPGPQVQSDAEIDAFVRQKADSAYHPSCTCKMGSPSDPMAVVGADTRVLGLDRLRVVDASIMPSIVSGNLNAPTIMIAEKAADIIRGRPPLVDPGVPVYQPPTLETQR 627          
BLAST of Choline dehydrogenase vs. Planmine SMEST
Match: SMESG000055689.1 (SMESG000055689.1)

HSP 1 Score: 775.778 bits (2002), Expect = 0.000e+0
Identity = 367/381 (96.33%), Postives = 369/381 (96.85%), Query Frame = 2
Query:  584 MIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTC 1726
            MIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYL+PVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVL KEGKLENV ANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHP+IDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYR EEMSPGPLVQTDKQMEEFIKNY      P  T 
Sbjct:    1 MIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLEPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLNKEGKLENVFANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPSIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRSEEMSPGPLVQTDKQMEEFIKNYKTRKLMPDQTV 381          
BLAST of Choline dehydrogenase vs. Planmine SMEST
Match: SMESG000055689.1 (SMESG000055689.1)

HSP 1 Score: 771.155 bits (1990), Expect = 0.000e+0
Identity = 365/370 (98.65%), Postives = 367/370 (99.19%), Query Frame = 2
Query:  584 MIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNY 1693
            MIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYL+PVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVL KEGKLENV ANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHP+IDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYR EEMSPGPLVQTDKQMEEFIKNY
Sbjct:    1 MIYMRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLEPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLNKEGKLENVFANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPSIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRSEEMSPGPLVQTDKQMEEFIKNY 370          
BLAST of Choline dehydrogenase vs. Planmine SMEST
Match: SMESG000055689.1 (SMESG000055689.1)

HSP 1 Score: 768.074 bits (1982), Expect = 0.000e+0
Identity = 364/378 (96.30%), Postives = 366/378 (96.83%), Query Frame = 2
Query:  593 MRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTC 1726
            MRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYL+PVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVL KEGKLENV ANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHP+IDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYR EEMSPGPLVQTDKQMEEFIKNY      P  T 
Sbjct:    1 MRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLEPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLNKEGKLENVFANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPSIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRSEEMSPGPLVQTDKQMEEFIKNYKTRKLMPDQTV 378          
BLAST of Choline dehydrogenase vs. Planmine SMEST
Match: SMESG000055689.1 (SMESG000055689.1)

HSP 1 Score: 764.992 bits (1974), Expect = 0.000e+0
Identity = 362/367 (98.64%), Postives = 364/367 (99.18%), Query Frame = 2
Query:  593 MRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNY 1693
            MRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYL+PVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVL KEGKLENV ANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHP+IDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYR EEMSPGPLVQTDKQMEEFIKNY
Sbjct:    1 MRGHPYDYDRWEKQGASGWSYSSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAGYGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLEPVMKNKHLTVTTDSLVTKVIFEGKRAIGVKVLNKEGKLENVFANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPSIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRSEEMSPGPLVQTDKQMEEFIKNY 367          
BLAST of Choline dehydrogenase vs. Planmine SMEST
Match: SMESG000055659.1 (SMESG000055659.1)

HSP 1 Score: 452.981 bits (1164), Expect = 2.070e-154
Identity = 212/341 (62.17%), Postives = 269/341 (78.89%), Query Frame = 2
Query:  956 LVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSGVGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSL--QSPEFKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLDHGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDICEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHTYHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAPTMMIAEKVADMILGKKPLPKL-NVPIWTPKNPSKQREAE 1969
            +VTK++F+GK+A+G+++L K   L  +M NKE+IL GGA+NSP LL+LSGVGDG ELK+HS+++V H+PGVGKN QDH  +YV+++ KKPVTL+S   + P    ++   W   K+G GAT HL SGGFIRSE  V HPD+QFHF P  ++DHGR+  T H+FQ  V P+RS+SKGSI++ S DP++HP IDPNY S +RD  EF+ AI+LTREI +QSAFDE+RGEE+ PG   Q+D+Q++EFI+  ++  YHP+ TC+MG+T  NDTVVD QCRVVG++NLRVVDASVMPSIVSGN NAPTMMIAEKVADMILG  PLPKL NVPIW PK P KQRE+E
Sbjct:    1 MVTKILFDGKKAVGIEILDKNKILNKIMVNKEIILSGGAVNSPQLLMLSGVGDGAELKQHSIDVVNHVPGVGKNLQDHLELYVQHKSKKPVTLYSATWKFPHNVIRIGLQWFLFKSGMGATSHLDSGGFIRSEPGVAHPDLQFHFLPSTVIDHGRKLATFHAFQAHVGPMRSQSKGSITILSNDPRQHPLIDPNYNSLKRDFWEFRKAIRLTREIFSQSAFDEFRGEEILPGSDAQSDEQLDEFIRQKTDTAYHPSCTCRMGSTKSNDTVVDPQCRVVGLDNLRVVDASVMPSIVSGNLNAPTMMIAEKVADMILGNDPLPKLENVPIWIPKYPMKQRESE 341          
The following BLAST results are available for this feature:
BLAST of Choline dehydrogenase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CHDH0.000e+050.00choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC... [more]
CHDH4.049e-2945.83choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC... [more]
CHDH1.770e-1339.56choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Choline dehydrogenase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C34C6.41.027e-17746.32pep chromosome:WBcel235:II:8696591:8698928:-1 gene... [more]
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BLAST of Choline dehydrogenase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG95184.693e-9335.55gene:FBgn0030590 transcript:FBtr0073983[more]
CG95184.693e-9335.55gene:FBgn0030590 transcript:FBtr0343598[more]
CG95184.693e-9335.55gene:FBgn0030590 transcript:FBtr0344175[more]
CG95034.337e-9135.75gene:FBgn0030598 transcript:FBtr0073974[more]
CG95146.354e-8933.80gene:FBgn0030592 transcript:FBtr0073980[more]
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BLAST of Choline dehydrogenase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
chdh0.000e+052.10choline dehydrogenase [Source:ZFIN;Acc:ZDB-GENE-12... [more]
chdh0.000e+052.10choline dehydrogenase [Source:ZFIN;Acc:ZDB-GENE-12... [more]
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BLAST of Choline dehydrogenase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Choline dehydrogenase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Chdh0.000e+049.46choline dehydrogenase [Source:MGI Symbol;Acc:MGI:1... [more]
Chdh0.000e+049.46choline dehydrogenase [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of Choline dehydrogenase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6UPE0|CHDH_RAT0.000e+050.54Choline dehydrogenase, mitochondrial OS=Rattus nor... [more]
sp|Q8BJ64|CHDH_MOUSE0.000e+049.46Choline dehydrogenase, mitochondrial OS=Mus muscul... [more]
sp|Q8NE62|CHDH_HUMAN0.000e+050.00Choline dehydrogenase, mitochondrial OS=Homo sapie... [more]
sp|A6X2G7|BETA_OCHA49.582e-18045.26Oxygen-dependent choline dehydrogenase OS=Ochrobac... [more]
sp|A9M9H8|BETA_BRUC21.612e-17945.26Oxygen-dependent choline dehydrogenase OS=Brucella... [more]
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BLAST of Choline dehydrogenase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A091REX20.000e+051.44Choline dehydrogenase OS=Merops nubicus OX=57421 G... [more]
A0A091MUR40.000e+051.17Choline dehydrogenase OS=Acanthisitta chloris OX=5... [more]
A0A091PFX10.000e+050.59Choline dehydrogenase OS=Leptosomus discolor OX=18... [more]
A0A091EN480.000e+050.76Choline dehydrogenase OS=Corvus brachyrhynchos OX=... [more]
A0A3M0JI140.000e+049.04Choline dehydrogenase OS=Hirundo rustica rustica O... [more]
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BLAST of Choline dehydrogenase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
chdh0.000e+048.79choline dehydrogenase [Source:NCBI gene;Acc:103039... [more]
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BLAST of Choline dehydrogenase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000002402.13.466e-10447.16pep scaffold:Pmarinus_7.0:GL482915:11564:16540:1 g... [more]
ENSPMAT00000007537.14.982e-3345.67pep scaffold:Pmarinus_7.0:GL493288:965:4963:-1 gen... [more]
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BLAST of Choline dehydrogenase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Choline dehydrogenase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO389561.596e-12248.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO389584.621e-8449.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Choline dehydrogenase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
chdh0.000e+051.07choline dehydrogenase [Source:NCBI gene;Acc:101161... [more]
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BLAST of Choline dehydrogenase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000055689.10.000e+096.33SMESG000055689.1[more]
SMESG000055689.10.000e+098.65SMESG000055689.1[more]
SMESG000055689.10.000e+096.30SMESG000055689.1[more]
SMESG000055689.10.000e+098.64SMESG000055689.1[more]
SMESG000055659.12.070e-15462.17SMESG000055659.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014360 ID=SMED30014360|Name=Choline dehydrogenase|organism=Schmidtea mediterranea sexual|type=transcript|length=2267bp
GTGCAATCTTGACAATATCAAATTAAAATTCACTGCTAATCATTAAAACA
AAAAAATGTTTTCATGTGGCCGCCTGGTTCAAATTTCTAGGAAGACAGAA
AATCCCGTTCCAAAGCTGTTGAACATTGTTGGCAAAGGTTATTTTATTCA
AAACTCCAGACAATTCTCAATAGCATCCAATAAATTGATATCTGCCAACC
AGAATGGGTTTAGAGGTTATACTCTAAAATCGAAAATATTTGACAAAAAC
ATATCTGTGCAAAACAGTCAAATAAGGTCACTTCATTTATGCAGAATTCT
ACAAACCAAAAAGGACACTGATTATGTAATTGTTGGAGCCGGATCGGCAG
GATGTGTATTGGCGAATAGACTTTTGGCCGATGGCAAGAACACTGTACAC
TTAATGGAAGCCGGCTCAACAGATAAAAATAGAACTATTCAAATTCCATT
AGCTTTGGGAGAGTTGATGGGGGGACATGAGTTCAACTGGTGTTTCGAAA
CGAAACCTCAGTTGCATTTGAATAAACGGAAAATATTTCTTCCAAGGGGC
AAAGTTATTGGGGGCAGCTCATCAATTAACGGGATGATTTATATGCGAGG
TCATCCGTATGACTATGACCGATGGGAAAAACAGGGAGCTTCTGGTTGGT
CATACAGTTCTTGTTTGCCCTACTTCAAAAAGGCCGAAAAACACGAAGCA
GGAGAAAATTTATATCACGGTGGAAATGGGCCTTTGCACGTCACTAGAAG
TAAAATAAATCAAGTTCTTCATGAAACTTGGGTCAAAGCGGGAACACAAG
CTGGATACGGTCATGCGGAAGATTTCAACGGTTTTAGGCAGGAAGGATTT
GGTCATTTTGATATGACAATTCACAAAGGAGAGAGGTGGTCATCGGCTAA
AGCCTATCTTGATCCAGTCATGAAGAACAAGCATCTAACAGTTACTACAG
ACAGCTTGGTTACAAAAGTCATTTTTGAAGGTAAACGAGCAATCGGAGTT
AAAGTTTTGACCAAAGAAGGAAAATTAGAAAATGTTATGGCTAACAAAGA
GGTTATTTTGTGCGGTGGCGCGATTAACAGTCCACATTTACTGTTACTCA
GTGGTGTAGGTGACGGAAATGAGCTAAAAAAACATTCCGTTAATATTGTT
GAACACATTCCAGGAGTAGGGAAAAATTTTCAAGATCATCCTACAATTTA
TGTACGATATCAATGCAAAAAACCCGTTACGCTATTTTCACTGCAATCGC
CCGAGTTCAAGAAAAAAGTTGATCAGGATTGGGACGAACACAAAACTGGC
TACGGAGCTACAGTTCACTTGACATCCGGTGGATTCATAAGGTCCGAAGC
TAATGTCACCCATCCAGATATACAATTCCATTTTTTCCCGGGACTTTTAT
TAGATCACGGCCGACAGACGATGACAAGCCATTCTTTTCAAATGTTCGTT
TCTCCTTTGAGATCCGAATCAAAAGGCTCCATTTCACTGCATTCAATTGA
TCCGAAGGAGCACCCAGCAATAGACCCGAATTATTGCTCATCTGAAAGAG
ATATCTGTGAATTTAAATCGGCTATTAAACTAACTAGAGAAATCATAGCT
CAGTCAGCTTTTGATGAGTACAGAGGCGAGGAAATGAGTCCCGGTCCACT
TGTCCAGACCGATAAGCAGATGGAAGAATTCATTAAGAACTATAGCGAAC
ATACGTACCATCCAACGTCAACTTGCAAAATGGGAGCAACGAATGGCAAC
GATACAGTTGTTGATTCGCAATGTCGAGTAGTCGGAGTGGAGAATTTGCG
CGTAGTTGACGCGTCCGTTATGCCAAGCATTGTCAGTGGGAATACGAACG
CACCAACAATGATGATTGCTGAAAAAGTGGCAGATATGATTCTTGGGAAA
AAGCCACTGCCGAAATTAAACGTTCCAATTTGGACCCCAAAAAATCCTAG
CAAGCAAAGAGAAGCCGAATAAATTATTGGATAGCGAAAATAATTTGATT
TTTAATTTTATTAAATTCCATTACTATCAAAATTTCATCTCTAAATTTTA
TTTAATTATAACAATTTAGTTGAATATTTTTAATCCTAAACATTTTTAAC
CATTGGGTAGGCATAGACAGCATATTTGGAGCTTTTTGGCCACCCCTTAC
TACTTATGGAAAGACAGAAACTAATAAATAATTTACATTTCACATTGATG
AGCATTGATTAAACAAAATGTAGTAAAATATTGAAAGGTTAAACGTTAAT
TTTTATGAATTATTTAT
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protein sequence of SMED30014360-orf-1

>SMED30014360-orf-1 ID=SMED30014360-orf-1|Name=SMED30014360-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=639bp
MFSCGRLVQISRKTENPVPKLLNIVGKGYFIQNSRQFSIASNKLISANQN
GFRGYTLKSKIFDKNISVQNSQIRSLHLCRILQTKKDTDYVIVGAGSAGC
VLANRLLADGKNTVHLMEAGSTDKNRTIQIPLALGELMGGHEFNWCFETK
PQLHLNKRKIFLPRGKVIGGSSSINGMIYMRGHPYDYDRWEKQGASGWSY
SSCLPYFKKAEKHEAGENLYHGGNGPLHVTRSKINQVLHETWVKAGTQAG
YGHAEDFNGFRQEGFGHFDMTIHKGERWSSAKAYLDPVMKNKHLTVTTDS
LVTKVIFEGKRAIGVKVLTKEGKLENVMANKEVILCGGAINSPHLLLLSG
VGDGNELKKHSVNIVEHIPGVGKNFQDHPTIYVRYQCKKPVTLFSLQSPE
FKKKVDQDWDEHKTGYGATVHLTSGGFIRSEANVTHPDIQFHFFPGLLLD
HGRQTMTSHSFQMFVSPLRSESKGSISLHSIDPKEHPAIDPNYCSSERDI
CEFKSAIKLTREIIAQSAFDEYRGEEMSPGPLVQTDKQMEEFIKNYSEHT
YHPTSTCKMGATNGNDTVVDSQCRVVGVENLRVVDASVMPSIVSGNTNAP
TMMIAEKVADMILGKKPLPKLNVPIWTPKNPSKQREAE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000018Category 4 cell
PLANA:0000034epidermis
PLANA:0000420parapharyngeal region
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036188FAD/NAD-bd_sf
IPR000172GMC_OxRdtase_N
IPR012132GMC_OxRdtase
IPR007867GMC_OxRtase_C
IPR023753FAD/NAD-binding_dom
Vocabulary: molecular function
TermDefinition
GO:0050660flavin adenine dinucleotide binding
GO:0016614oxidoreductase activity, acting on CH-OH group of donors
GO:0016491oxidoreductase activity
GO:0008812choline dehydrogenase activity
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0019285glycine betaine biosynthetic process from choline
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.30.410.40coord: 3..98
e-value: 7.3E-58
score: 198.6
NoneNo IPR availablePANTHERPTHR11552GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASEcoord: 2..173
NoneNo IPR availablePANTHERPTHR11552:SF147CHOLINE DEHYDROGENASE, MITOCHONDRIALcoord: 2..173
NoneNo IPR availableSUPERFAMILYSSF54373FAD-linked reductases, C-terminal domaincoord: 3..101
IPR036188FAD/NAD(P)-binding domain superfamilyGENE3DG3DSA:3.50.50.60coord: 18..157
e-value: 7.3E-58
score: 198.6
IPR036188FAD/NAD(P)-binding domain superfamilySUPERFAMILYSSF51905FAD/NAD(P)-binding domaincoord: 97..161
IPR007867Glucose-methanol-choline oxidoreductase, C-terminalPFAMPF05199GMC_oxred_Ccoord: 16..152
e-value: 2.5E-41
score: 141.5