SMED30014336

Overview
NameSMED30014336
Smed IDSMED30014336
Length (bp)1358
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30014336 (SMED30014336) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30014336 (SMED30014336) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30014336 (SMED30014336) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30014336 (SMED30014336) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30014336

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30014336SMESG000007194.1 Contig3313GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30014336SMESG000075510.1 SMESG000009592.1 Contig3313GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
epidermisSMED30014336SMESG000075510.1 SMESG000009592.1 dd_Smed_v4_6087_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014336SMESG000075510.1 SMESG000009592.1 dd_Smed_v4_6087_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30014336SMESG000075510.1 SMESG000009592.1 dd_Smed_v4_6087_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30014336SMESG000075510.1 SMESG000009592.1 dd_Smed_v6_6087_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30014336SMESG000075510.1 SMESG000009592.1 dd_Smed_v4_6087_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30014336 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.009524:6980..8382 -6707
Homology
BLAST of SMED30014336 vs. Planmine SMEST
Match: SMESG000075510.1 (SMESG000075510.1)

HSP 1 Score: 736.873 bits (1901), Expect = 0.000e+0
Identity = 418/424 (98.58%), Postives = 421/424 (99.29%), Query Frame = 1
Query:   82 MGNFDQISELLKKYQFEKNPQLKSNLIRRICQQIAINRCHGDCGCNFFFKFMENFIPVDNKLFPTDCSDCKWFKIIFNINVFDDNHIDIVENSLIKYPFKSHNCDTESEIMSDNGNICIQFLLVYPVAEFGCTTSNMRGESVIDRLVGGIRQRKFIVNELMVSRCSQSQEYLKEYXXXXXXXXXXXXNYIKIVFNLNALKNEVHELKQRISDTMNETIRMIFHLKEELDKIIMDXXXXXXXXXXXXXXXXXXXXXXXXXXXDSNLIKMGDGNTIDHFDREIPDVNLWTSPMKPFRSFCFCFNNISHLKTKWAVDSDKFLSNDGQYEIILQLWPRGCSHGHQDSHVCMEXXXXXXXXXXXXXXXKCRVKLCLGSHSTINVEKYLMFFDDSTVRGLPQFHFHKSDLNRSGVIEIDSLKISCEIFID 1353
            MGNFDQISELLKKYQFEKNPQLKSNLIRRICQQIA+NRCHGDCGCNFFFKFMENFIP DNKLFPTDCSDCKWFKIIFN+NVFDDNHIDIVENSLIKYPFKSHNCDTESEIMSDNGNICIQFLLVY VAEFGCTTSNMRGESVIDRL+GGIRQRKFIVNELMVSRCSQSQEYLKEYLPLISSSQSLLLNYIKIVFNLNALKNEVHELKQRISD MNETIRMIFHLKEELDKIIMDIENINNELIVENQEIKKENIKLKKQIKDSNLIKMGDGNTIDHFDREIPDVNLWTSPMKPFRSFCFCFNNISHLKTKWAVDSDKFLSNDGQYEIILQLWPRGCSHGHQDSHVCMELSISSLVDSLSVPSLKCRVKLCLGSHSTINVEKYLMFFDDSTVRGLPQFHFHKSDLNRSGVIEIDSLKISCEIFID
Sbjct:    1 MGNFDQISELLKKYQFEKNPQLKSNLIRRICQQIAVNRCHGDCGCNFFFKFMENFIPADNKLFPTDCSDCKWFKIIFNLNVFDDNHIDIVENSLIKYPFKSHNCDTESEIMSDNGNICIQFLLVYSVAEFGCTTSNMRGESVIDRLIGGIRQRKFIVNELMVSRCSQSQEYLKEYLPLISSSQSLLLNYIKIVFNLNALKNEVHELKQRISDIMNETIRMIFHLKEELDKIIMDIENINNELIVENQEIKKENIKLKKQIKDSNLIKMGDGNTIDHFDREIPDVNLWTSPMKPFRSFCFCFNNISHLKTKWAVDSDKFLSNDGQYEIILQLWPRGCSHGHQDSHVCMELSISSLVDSLSVPSLKCRVKLCLGSHSTINVEKYLMFFDDSTVRGLPQFHFHKSDLNRSGVIEIDSLKISCEIFID 424          
BLAST of SMED30014336 vs. Planmine SMEST
Match: SMESG000009592.1 (SMESG000009592.1)

HSP 1 Score: 736.873 bits (1901), Expect = 0.000e+0
Identity = 418/424 (98.58%), Postives = 421/424 (99.29%), Query Frame = 1
Query:   82 MGNFDQISELLKKYQFEKNPQLKSNLIRRICQQIAINRCHGDCGCNFFFKFMENFIPVDNKLFPTDCSDCKWFKIIFNINVFDDNHIDIVENSLIKYPFKSHNCDTESEIMSDNGNICIQFLLVYPVAEFGCTTSNMRGESVIDRLVGGIRQRKFIVNELMVSRCSQSQEYLKEYXXXXXXXXXXXXNYIKIVFNLNALKNEVHELKQRISDTMNETIRMIFHLKEELDKIIMDXXXXXXXXXXXXXXXXXXXXXXXXXXXDSNLIKMGDGNTIDHFDREIPDVNLWTSPMKPFRSFCFCFNNISHLKTKWAVDSDKFLSNDGQYEIILQLWPRGCSHGHQDSHVCMEXXXXXXXXXXXXXXXKCRVKLCLGSHSTINVEKYLMFFDDSTVRGLPQFHFHKSDLNRSGVIEIDSLKISCEIFID 1353
            MGNFDQISELLKKYQFEKNPQLKSNLIRRICQQIA+NRCHGDCGCNFFFKFMENFIP DNKLFPTDCSDCKWFKIIFN+NVFDDNHIDIVENSLIKYPFKSHNCDTESEIMSDNGNICIQFLLVY VAEFGCTTSNMRGESVIDRL+GGIRQRKFIVNELMVSRCSQSQEYLKEYLPLISSSQSLLLNYIKIVFNLNALKNEVHELKQRISD MNETIRMIFHLKEELDKIIMDIENINNELIVENQEIKKENIKLKKQIKDSNLIKMGDGNTIDHFDREIPDVNLWTSPMKPFRSFCFCFNNISHLKTKWAVDSDKFLSNDGQYEIILQLWPRGCSHGHQDSHVCMELSISSLVDSLSVPSLKCRVKLCLGSHSTINVEKYLMFFDDSTVRGLPQFHFHKSDLNRSGVIEIDSLKISCEIFID
Sbjct:    1 MGNFDQISELLKKYQFEKNPQLKSNLIRRICQQIAVNRCHGDCGCNFFFKFMENFIPADNKLFPTDCSDCKWFKIIFNLNVFDDNHIDIVENSLIKYPFKSHNCDTESEIMSDNGNICIQFLLVYSVAEFGCTTSNMRGESVIDRLIGGIRQRKFIVNELMVSRCSQSQEYLKEYLPLISSSQSLLLNYIKIVFNLNALKNEVHELKQRISDIMNETIRMIFHLKEELDKIIMDIENINNELIVENQEIKKENIKLKKQIKDSNLIKMGDGNTIDHFDREIPDVNLWTSPMKPFRSFCFCFNNISHLKTKWAVDSDKFLSNDGQYEIILQLWPRGCSHGHQDSHVCMELSISSLVDSLSVPSLKCRVKLCLGSHSTINVEKYLMFFDDSTVRGLPQFHFHKSDLNRSGVIEIDSLKISCEIFID 424          
BLAST of SMED30014336 vs. Planmine SMEST
Match: SMESG000049832.1 (SMESG000049832.1)

HSP 1 Score: 71.2478 bits (173), Expect = 5.071e-13
Identity = 58/238 (24.37%), Postives = 116/238 (48.74%), Query Frame = 1
Query:   91 FDQISELLKKYQFEKNPQLKSNLIRRICQQIAINRCHGDCGCNFFFKFMENFIPVDNKLFPTDCSDCKWFKIIFNINVFDDNHIDI-VENSLIKYPFKSHNCDTESEI--MSDNGNICIQFLLVYPVAEFGCTTSNMRGESVIDRLVGGIRQRKFIVNELMVSRCS----QSQEYLKEYXXXXXXXXXXXXNYIKIVFNLNALKN---EVHELKQRISDTMNETIRMIFHLKEELDKI 774
            F  + +++++ +FE + ++ S L  RIC+ + I  C+  CGC F    +E ++  D+K  P +   C++  I F  NV +D+ I++ +   ++K P    NC+ ++E+  M ++ N C + L+ YP   FGC  +    E   D +   + +  +  ++L+++  +    Q +  + E + L      +  N +K   N+  L N    V +  Q + D M E  +     K+++D I
Sbjct:    2 FTNLWKMMRENKFESDNEISSELKCRICKCLMIKACNAPCGCRFCSDCIEQYLRKDDKFCPGEAEYCQFQMINFTRNVSEDHPINLRISKVIVKCP--RQNCEIKTELIKMEEHMNNCDKRLISYPFNTFGCAIN----EVASDEMNAHLNESNYCHSKLLIAMINNLNRQMESMMNENMKLRQRMGHMEANEMKNTKNIEDLNNAIVAVEKNNQSLRDEMTELSKENRKFKQQIDTI 233          
BLAST of SMED30014336 vs. Planmine SMEST
Match: SMESG000049832.1 (SMESG000049832.1)

HSP 1 Score: 69.707 bits (169), Expect = 1.349e-12
Identity = 57/232 (24.57%), Postives = 113/232 (48.71%), Query Frame = 1
Query:  109 LLKKYQFEKNPQLKSNLIRRICQQIAINRCHGDCGCNFFFKFMENFIPVDNKLFPTDCSDCKWFKIIFNINVFDDNHIDI-VENSLIKYPFKSHNCDTESEI--MSDNGNICIQFLLVYPVAEFGCTTSNMRGESVIDRLVGGIRQRKFIVNELMVSRCS----QSQEYLKEYXXXXXXXXXXXXNYIKIVFNLNALKN---EVHELKQRISDTMNETIRMIFHLKEELDKI 774
            ++++ +FE + ++ S L  RIC+ + I  C+  CGC F    +E ++  D+K  P +   C++  I F  NV +D+ I++ +   ++K P    NC+ ++E+  M ++ N C + L+ YP   FGC  +    E   D +   + +  +  ++L+++  +    Q +  + E + L      +  N +K   N+  L N    V +  Q + D M E  +     K+++D I
Sbjct:    1 MMRENKFESDNEISSELKCRICKCLMIKACNAPCGCRFCSDCIEQYLRKDDKFCPGEAEYCQFQMINFTRNVSEDHPINLRISKVIVKCP--RQNCEIKTELIKMEEHMNNCDKRLISYPFNTFGCAIN----EVASDEMNAHLNESNYCHSKLLIAMINNLNRQMESMMNENMKLRQRMGHMEANEMKNTKNIEDLNNAIVAVEKNNQSLRDEMTELSKENRKFKQQIDTI 226          
BLAST of SMED30014336 vs. Planmine SMEST
Match: SMESG000049567.1 (SMESG000049567.1)

HSP 1 Score: 66.6254 bits (161), Expect = 1.304e-11
Identity = 38/142 (26.76%), Postives = 77/142 (54.23%), Query Frame = 1
Query:   91 FDQISELLKKYQFEKNPQLKSNLIRRICQQIAINRCHGDCGCNFFFKFMENFIPVDNKLFPTDCSDCKWFKIIFNINVFDDNHIDI-VENSLIKYPFKSHNCDTESEI--MSDNGNICIQFLLVYPVAEFGCTTSNMRGESV 507
            F  + +++++ +FE + ++ S+L+ RIC+++ I  CH  CGC F    +E ++   +K  P +   C+  KI F  NV +D+  +I +   ++K P  + NC+T++E+  M ++   C +  +  P    GC  + +  E +
Sbjct:    2 FTNLWKMMRENKFESDNEISSDLLCRICKRLMIKACHTPCGCRFCSDCIEQYLNETDKFCPGEAKYCQVQKINFTRNVSEDHPTNIRISEVIVKCP--TQNCETKTELSMMEEHIRTCDKRPISCPFISIGCEINEIANEEI 141          
The following BLAST results are available for this feature:
BLAST of SMED30014336 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30014336 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000075510.10.000e+098.58SMESG000075510.1[more]
SMESG000009592.10.000e+098.58SMESG000009592.1[more]
SMESG000049832.15.071e-1324.37SMESG000049832.1[more]
SMESG000049832.11.349e-1224.57SMESG000049832.1[more]
SMESG000049567.11.304e-1126.76SMESG000049567.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014336 ID=SMED30014336|Name=SMED30014336|organism=Schmidtea mediterranea sexual|type=transcript|length=1358bp
GTTATAATAGTTAATGAACCAAATCGATATTTTATTGATTGAAGAATTAA
TTTAATTTTTGGATTTAAACCATCAAAATAAATGGGAAACTTTGATCAAA
TTTCCGAATTATTGAAAAAATATCAATTCGAAAAAAATCCTCAACTGAAA
AGTAATTTAATTCGTAGAATTTGTCAGCAAATAGCTATCAATCGATGCCA
TGGAGATTGCGGATGTAATTTTTTTTTCAAATTCATGGAAAATTTTATAC
CTGTTGACAATAAATTATTTCCTACTGATTGTTCCGATTGTAAATGGTTT
AAAATTATCTTTAATATCAATGTTTTCGATGACAACCATATAGATATAGT
TGAAAATTCATTAATAAAATACCCTTTCAAGTCTCATAATTGTGATACTG
AATCGGAAATAATGTCGGACAACGGTAACATTTGTATTCAATTTCTATTG
GTTTATCCTGTTGCTGAGTTCGGATGCACAACAAGTAATATGAGAGGAGA
ATCTGTTATCGATCGTCTGGTTGGTGGAATTCGTCAACGGAAATTTATAG
TAAATGAACTAATGGTTTCCAGGTGTTCCCAAAGTCAAGAATATCTTAAG
GAATATTTACCACTTATCAGTTCAAGCCAGTCCCTGTTACTCAATTATAT
TAAAATTGTATTTAACTTGAATGCGCTAAAGAACGAAGTCCATGAGTTAA
AACAAAGAATTTCTGACACTATGAATGAAACGATTAGAATGATTTTTCAT
TTGAAAGAAGAATTGGATAAAATTATTATGGACATAGAAAACATAAACAA
CGAGCTAATTGTGGAAAACCAAGAAATAAAAAAGGAAAATATTAAATTAA
AAAAACAAATTAAAGATTCAAACCTAATCAAAATGGGAGACGGAAATACA
ATTGATCATTTTGATAGGGAAATACCTGATGTTAATTTATGGACTTCTCC
GATGAAACCGTTTCGGTCATTTTGCTTTTGTTTTAATAATATTTCTCATT
TGAAAACTAAATGGGCAGTCGATAGTGATAAATTTCTTTCTAATGATGGC
CAATATGAAATAATATTACAATTGTGGCCTCGAGGTTGTTCACATGGTCA
TCAAGACAGCCACGTTTGTATGGAATTGTCGATCAGTAGTCTTGTTGATT
CTCTCTCAGTTCCATCATTAAAATGCCGAGTGAAATTATGTTTAGGATCT
CATTCCACAATAAACGTCGAGAAATATCTGATGTTTTTCGATGATTCCAC
TGTACGTGGTTTGCCTCAATTCCATTTCCACAAGTCTGATCTCAATCGGT
CTGGGGTCATTGAAATTGATTCACTGAAAATTAGCTGTGAGATCTTTATC
GACTAAGG
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protein sequence of SMED30014336-orf-1

>SMED30014336-orf-1 ID=SMED30014336-orf-1|Name=SMED30014336-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=425bp
MGNFDQISELLKKYQFEKNPQLKSNLIRRICQQIAINRCHGDCGCNFFFK
FMENFIPVDNKLFPTDCSDCKWFKIIFNINVFDDNHIDIVENSLIKYPFK
SHNCDTESEIMSDNGNICIQFLLVYPVAEFGCTTSNMRGESVIDRLVGGI
RQRKFIVNELMVSRCSQSQEYLKEYLPLISSSQSLLLNYIKIVFNLNALK
NEVHELKQRISDTMNETIRMIFHLKEELDKIIMDIENINNELIVENQEIK
KENIKLKKQIKDSNLIKMGDGNTIDHFDREIPDVNLWTSPMKPFRSFCFC
FNNISHLKTKWAVDSDKFLSNDGQYEIILQLWPRGCSHGHQDSHVCMELS
ISSLVDSLSVPSLKCRVKLCLGSHSTINVEKYLMFFDDSTVRGLPQFHFH
KSDLNRSGVIEIDSLKISCEIFID*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR002083MATH/TRAF_dom
IPR008974TRAF-like
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0004842ubiquitin-protein transferase activity
GO:0008270zinc ion binding
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006955immune response
GO:0007165signal transduction
GO:0016567protein ubiquitination
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 196..216
NoneNo IPR availableCOILSCoilCoilcoord: 221..259
IPR008974TRAF-likeGENE3DG3DSA:2.60.210.10coord: 295..424
e-value: 4.9E-6
score: 28.7
IPR008974TRAF-likeSUPERFAMILYSSF49599TRAF domain-likecoord: 296..423
IPR002083MATH/TRAF domainPROSITEPS50144MATHcoord: 294..421
score: 9.473