Vasohibin-2

Overview


Name	Vasohibin-2
Smed ID	SMED30014325
Length (bp)	972

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30014325

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
reproductive organ	SMED30014325	SMESG000069763.1	Contig27162	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30014325	SMESG000069763.1	Contig27162	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
testis	SMED30014325	SMESG000069763.1	PL08009B1F09	ncbi_smed_ests	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Vasohibin-2 vs. Ensembl Human
Match: VASH1 (vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964])

HSP 1 Score: 176.792 bits (447), Expect = 5.949e-52
Identity = 82/239 (34.31%), Postives = 140/239 (58.58%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN G  P++  TW+ +       +P      + +   T+L +  +P VP F     + E++  VQ ++ +L+YN+TG QFF+I K + +  LMD AK++   +LPIKCLEA+ILGIYLTN + ++ERF I F + F G  ++HIVLG+    R+G++G+SRR +LMYKP  +++L +L+ +F+  Y    H+L    +  S+ H     + + W+   ++  +L  +   K+L  ++
Sbjct:   60 FFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHA 298

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BLAST of Vasohibin-2 vs. Ensembl Human
Match: VASH2 (vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723])

HSP 1 Score: 175.637 bits (444), Expect = 1.186e-51
Identity = 86/237 (36.29%), Postives = 139/237 (58.65%), Query Frame = 3

Query:  120 VNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            VN+  FP++  TW+ +       +P     +  +     L +  +PQVP +    +I + +  +Q+++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR+ LM KPL +++L DL+ +F+  Y++  H +    +   + H       + W+ L +N  K+    I K+L  Y+
Sbjct:   51 VNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYA 287

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BLAST of Vasohibin-2 vs. Ensembl Human
Match: VASH2 (vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723])

HSP 1 Score: 163.31 bits (412), Expect = 1.213e-47
Identity = 79/198 (39.90%), Postives = 124/198 (62.63%), Query Frame = 3

Query:  237 LIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            L +  +PQVP +    +I + +  +Q+++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR+ LM KPL +++L DL+ +F+  Y++  H +    +   + H       + W+ L +N  K+    I K+L  Y+
Sbjct:   25 LAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYA 222

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Query:  237 LIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            L +  +PQVP +    +I + +  +Q+++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR+ LM KPL +++L DL+ +F+  Y++  H +    +   + H       + W+ L +N  K+    I K+L  Y+
Sbjct:   25 LAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYA 222

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BLAST of Vasohibin-2 vs. Ensembl Human
Match: VASH2 (vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723])

HSP 1 Score: 154.066 bits (388), Expect = 1.455e-44
Identity = 74/182 (40.66%), Postives = 116/182 (63.74%), Query Frame = 3

Query:  285 SIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            +I + +  +Q+++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR+ LM KPL +++L DL+ +F+  Y++  H +    +   + H       + W+ L +N  K+    I K+L  Y+
Sbjct:    2 TIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYA 183

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BLAST of Vasohibin-2 vs. Ensembl Zebrafish
Match: VASH1 (vasohibin 1 [Source:NCBI gene;Acc:100001748])

HSP 1 Score: 191.43 bits (485), Expect = 7.941e-58
Identity = 90/239 (37.66%), Postives = 144/239 (60.25%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            +++N G  P+N  TW+++       +P      + +    +L +  +P VP F    SI  ++  +Q ++  L+YN+TG QFF+I K + + +LMD AK++   SLPIKCLEA+ILGIYLTN + SVERF + F +QF G  ++HIVLG+++  RFG++G+SRR +LMYK L YK+L DLL +F++ Y    H L    +   + H     + + W+   ++  KL  E + K+L  ++
Sbjct:   66 FIINRGGLPVNEETWEQMWRHVARIHPDGEQLARRIRGTRDLPKIPVPSVPTFQPSISIAHRLEAIQKYIRDLQYNHTGTQFFEIKKSRPLTALMDIAKEMTRESLPIKCLEAVILGIYLTNSMPSVERFPLSFKTQFSGSHFRHIVLGVHSGGRFGALGISRRQDLMYKSLQYKTLSDLLLDFQEAYRGHWHTLCRVRIGHYVSHDPHSVEQIEWKHSVLDVDKLTREELRKELERHT 304

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BLAST of Vasohibin-2 vs. Ensembl Zebrafish
Match: vash2 (vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355])

HSP 1 Score: 180.644 bits (457), Expect = 6.121e-55
Identity = 88/239 (36.82%), Postives = 142/239 (59.41%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN   FP+   TW+ + +     +P  +  +  +   T L +  +P VP F    S+ + +  VQ+++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN L SVERF I F +QF G  + H+VLG+Y N R+G++G+SRR++LM + L +++L +L+ +F+  Y   +H +    +   + H+  V   + W  L IN  K   E + K+L  + 
Sbjct:    4 FFVNRTGFPIESVTWERMWSHVAKVHPDGQEMVDRIRNATLLPKHSVPSVPNFKPSMSVPDWLHAVQNYMRNLQYNHTGTQFFEIKKTRPLSGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSVERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDRSLSFRTLSELVFDFEDSYRRYQHTMKKIKIGLYVPHNPHVFQPIEWNYLVINASKQGREDMRKELEKHG 242

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BLAST of Vasohibin-2 vs. Ensembl Zebrafish
Match: vash2 (vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355])

HSP 1 Score: 181.8 bits (460), Expect = 2.345e-54
Identity = 90/239 (37.66%), Postives = 145/239 (60.67%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQK-GLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSY 827
            + VN   FP+   TW+ + +     +P D  ++ D ++   L+ K  +P VP F    S+ + +  VQ+++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN L SVERF I F +QF G  + H+VLG+Y N R+G++G+SRR++LM + L +++L +L+ +F+  Y   +H +    +   + H+  V   + W  L IN  K   E + K+L  +
Sbjct:   62 FFVNRTGFPIESVTWERMWSHVAKVHP-DGQEMVDRIRNATLLPKHSVPSVPNFKPSMSVPDWLHAVQNYMRNLQYNHTGTQFFEIKKTRPLSGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSVERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDRSLSFRTLSELVFDFEDSYRRYQHTMKKIKIGLYVPHNPHVFQPIEWNYLVINASKQGREDMRKELEKH 299

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Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQK-GLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSY 827
            + VN   FP+   TW+ + +     +P D  ++ D ++   L+ K  +P VP F    S+ + +  VQ+++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN L SVERF I F +QF G  + H+VLG+Y N R+G++G+SRR++LM + L +++L +L+ +F+  Y   +H +    +   + H+  V   + W  L IN  K   E + K+L  +
Sbjct:   62 FFVNRTGFPIESVTWERMWSHVAKVHP-DGQEMVDRIRNATLLPKHSVPSVPNFKPSMSVPDWLHAVQNYMRNLQYNHTGTQFFEIKKTRPLSGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSVERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDRSLSFRTLSELVFDFEDSYRRYQHTMKKIKIGLYVPHNPHVFQPIEWNYLVINASKQGREDMRKELEKH 299

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BLAST of Vasohibin-2 vs. Ensembl Xenopus
Match: serinc5 (serine incorporator 5 [Source:Xenbase;Acc:XB-GENE-1008360])

HSP 1 Score: 189.504 bits (480), Expect = 3.935e-57
Identity = 87/239 (36.40%), Postives = 144/239 (60.25%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN G  P++  TW+ +  F    +P     ++ + +  +L +   P VP FH   ++ E+I  +Q ++ +L+YN+TG QFF+I K + +  LMD AK++   +LPIKCLEA+IL IYLTN +  +ERF I F +QF G  ++HIVLGL+    FG++G+SRR +LMYKPL +++L DLL +F+  Y +  H L    +   + H     + ++W+   ++  +L  E + ++L  +S
Sbjct:   45 FYVNRGGLPIDEPTWERMWQFVGKTHPDGEALVRRIREAQDLPRVPAPSVPSFHVGATVPERIEAIQRYIRELQYNHTGTQFFEIKKTRPLTGLMDLAKEMTKEALPIKCLEAVILAIYLTNSIAGLERFPISFKTQFSGGCFRHIVLGLHWGNHFGALGISRRDDLMYKPLKHRTLSDLLADFQDAYSKCWHTLRKVKIGRYVSHDPHSVEQIDWKHSVLDVQELGTEGLRRELERHS 283

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BLAST of Vasohibin-2 vs. Ensembl Xenopus
Match: mios (missing oocyte, meiosis regulator, homolog [Source:Xenbase;Acc:XB-GENE-5959761])

HSP 1 Score: 179.489 bits (454), Expect = 3.697e-53
Identity = 88/239 (36.82%), Postives = 143/239 (59.83%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN+  FP++ +TW+ +       +P  ++ +  +   T L +  +P VP +    SI E +  VQ ++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   SVERF I F +QF G  + H+VLG++ N  +G++G+SRRS+LM KPL +++L +L+ +F++ Y+   H +    +   + H       + W+ L IN  K+ +  I K L  ++
Sbjct:   72 FYVNKSGFPIDSQTWERMWGHVAKIHPEGKDMVDKIRNATLLAKPSIPAVPTYKASMSIPEWLQAVQRYMKLLQYNHTGTQFFEIRKTRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSVERFPISFKTQFSGSFFHHVVLGIHCNGHYGTLGMSRRSDLMDKPLTFRTLSELIFDFEESYKNYLHTVKKVKIGLYVPHDPHTFQPIEWKHLVINMGKMMKADIKKVLEKHA 310

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BLAST of Vasohibin-2 vs. Ensembl Xenopus
Match: mios (missing oocyte, meiosis regulator, homolog [Source:Xenbase;Acc:XB-GENE-5959761])

HSP 1 Score: 101.679 bits (252), Expect = 3.144e-24
Identity = 62/239 (25.94%), Postives = 109/239 (45.61%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN+  FP++ +TW+ +       +P  ++ +  +   T L +  +P VP +    SI E +  VQ ++  L+Y                                            LTN   SVERF I F +QF G  + H+VLG++ N  +G++G+SRRS+LM KPL +++L +L+ +F++ Y+   H +    +   + H       + W+ L IN  K+ +  I K L  ++
Sbjct:   72 FYVNKSGFPIDSQTWERMWGHVAKIHPEGKDMVDKIRNATLLAKPSIPAVPTYKASMSIPEWLQAVQRYMKLLQY--------------------------------------------LTNGQPSVERFPISFKTQFSGSFFHHVVLGIHCNGHYGTLGMSRRSDLMDKPLTFRTLSELIFDFEESYKNYLHTVKKVKIGLYVPHDPHTFQPIEWKHLVINMGKMMKADIKKVLEKHA 266

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BLAST of Vasohibin-2 vs. Ensembl Mouse
Match: Vash1 (vasohibin 1 [Source:MGI Symbol;Acc:MGI:2442543])

HSP 1 Score: 173.711 bits (439), Expect = 6.181e-51
Identity = 80/240 (33.33%), Postives = 138/240 (57.50%), Query Frame = 3

Query:  111 SYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
             + +N G  P++  TW+ +       +P        +   T+L +  +P VP F     + E++  VQ ++ +L+YN+TG QFF+I K + +  LMD AK++   +LPIKCLEA+ILGIYLTN + ++ERF I F + F G  ++HIVLG+    R+G++G+SRR +LMYKP  +++L +L+ +++  Y    H+L    +   + H     + + W+   ++  +L  E   K+L  ++
Sbjct:   69 PFFINRGGLPVDEATWERMWKHVAKIHPDGEKVALRIRGATDLPKIPIPSVPTFQPTTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFGGRYGALGMSRREDLMYKPPAFRTLSELVLDYEAAYGRCWHVLKKVKLGQCVSHDPHSVEQIEWKHSVLDVERLGREDFRKELERHA 308

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BLAST of Vasohibin-2 vs. Ensembl Mouse
Match: Vash2 (vasohibin 2 [Source:MGI Symbol;Acc:MGI:2444826])

HSP 1 Score: 171.4 bits (433), Expect = 2.997e-50
Identity = 85/237 (35.86%), Postives = 138/237 (58.23%), Query Frame = 3

Query:  120 VNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            VN+  FP++  TW+ +       +P     +  +     L +  +PQVP +    +I + +  +Q+++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   S+ERF I F + F G  + H+VLG+Y N  +GS+G+SRR+ LM KPL +++L DL+ +F+  Y++  H +    +   + H       + W+ L +N  K+    I K+L  Y+
Sbjct:   51 VNKSGFPIDSHTWERMWLHVAKVHPRGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGYYGSLGMSRRAELMDKPLTFRTLSDLVFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYA 287

[Close]

Query:  120 VNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            VN+  FP++  TW+ +       +P     +  +     L +  +PQVP +    +I + +  +Q+++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   S+ERF I F + F G  + H+VLG+Y N  +GS+G+SRR+ LM KPL +++L DL+ +F+  Y++  H +    +   + H       + W+ L +N  K+    I K+L  Y+
Sbjct:   51 VNKSGFPIDSHTWERMWLHVAKVHPRGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGYYGSLGMSRRAELMDKPLTFRTLSDLVFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYA 287

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BLAST of Vasohibin-2 vs. UniProt/SwissProt
Match: sp|Q7L8A9|VASH1_HUMAN (Tubulinyl-Tyr carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=VASH1 PE=1 SV=1)

HSP 1 Score: 176.792 bits (447), Expect = 2.857e-51
Identity = 82/239 (34.31%), Postives = 140/239 (58.58%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN G  P++  TW+ +       +P      + +   T+L +  +P VP F     + E++  VQ ++ +L+YN+TG QFF+I K + +  LMD AK++   +LPIKCLEA+ILGIYLTN + ++ERF I F + F G  ++HIVLG+    R+G++G+SRR +LMYKP  +++L +L+ +F+  Y    H+L    +  S+ H     + + W+   ++  +L  +   K+L  ++
Sbjct:   60 FFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHA 298

[Close]

BLAST of Vasohibin-2 vs. UniProt/SwissProt
Match: sp|Q86V25|VASH2_HUMAN (Tubulinyl-Tyr carboxypeptidase 2 OS=Homo sapiens OX=9606 GN=VASH2 PE=1 SV=2)

HSP 1 Score: 175.637 bits (444), Expect = 5.695e-51
Identity = 86/237 (36.29%), Postives = 139/237 (58.65%), Query Frame = 3

Query:  120 VNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            VN+  FP++  TW+ +       +P     +  +     L +  +PQVP +    +I + +  +Q+++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR+ LM KPL +++L DL+ +F+  Y++  H +    +   + H       + W+ L +N  K+    I K+L  Y+
Sbjct:   51 VNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYA 287

[Close]

BLAST of Vasohibin-2 vs. UniProt/SwissProt
Match: sp|Q8C1W1|VASH1_MOUSE (Tubulinyl-Tyr carboxypeptidase 1 OS=Mus musculus OX=10090 GN=Vash1 PE=1 SV=4)

HSP 1 Score: 173.711 bits (439), Expect = 4.323e-50
Identity = 80/240 (33.33%), Postives = 138/240 (57.50%), Query Frame = 3

Query:  111 SYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
             + +N G  P++  TW+ +       +P        +   T+L +  +P VP F     + E++  VQ ++ +L+YN+TG QFF+I K + +  LMD AK++   +LPIKCLEA+ILGIYLTN + ++ERF I F + F G  ++HIVLG+    R+G++G+SRR +LMYKP  +++L +L+ +++  Y    H+L    +   + H     + + W+   ++  +L  E   K+L  ++
Sbjct:   69 PFFINRGGLPVDEATWERMWKHVAKIHPDGEKVALRIRGATDLPKIPIPSVPTFQPTTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFGGRYGALGMSRREDLMYKPPAFRTLSELVLDYEAAYGRCWHVLKKVKLGQCVSHDPHSVEQIEWKHSVLDVERLGREDFRKELERHA 308

[Close]

BLAST of Vasohibin-2 vs. UniProt/SwissProt
Match: sp|Q8C5G2|VASH2_MOUSE (Tubulinyl-Tyr carboxypeptidase 2 OS=Mus musculus OX=10090 GN=Vash2 PE=1 SV=2)

HSP 1 Score: 171.4 bits (433), Expect = 2.096e-49
Identity = 85/237 (35.86%), Postives = 138/237 (58.23%), Query Frame = 3

Query:  120 VNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            VN+  FP++  TW+ +       +P     +  +     L +  +PQVP +    +I + +  +Q+++  L+YN+TG QFF+I K + +  LM+ AK++   SLPIKCLEA+ILGIYLTN   S+ERF I F + F G  + H+VLG+Y N  +GS+G+SRR+ LM KPL +++L DL+ +F+  Y++  H +    +   + H       + W+ L +N  K+    I K+L  Y+
Sbjct:   51 VNKSGFPIDSHTWERMWLHVAKVHPRGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGYYGSLGMSRRAELMDKPLTFRTLSDLVFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYA 287

[Close]

BLAST of Vasohibin-2 vs. TrEMBL
Match: A0A3B4BVF1 (Vasohibin 1 OS=Pygocentrus nattereri OX=42514 GN=VASH1 PE=4 SV=1)

HSP 1 Score: 200.675 bits (509), Expect = 6.816e-58
Identity = 93/240 (38.75%), Postives = 150/240 (62.50%), Query Frame = 3

Query:  111 SYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
             ++VN G  P+N  TW+++       +P      K +   T+L +  +P VP +    SI  ++  +Q ++  L+YN+TG QFF+I K + + +LMD AK++   SLPIKCLEA+ILGIYLTN++ SVERF I F +QF G  ++HIVLG+++  RFG++G+SRR +LM+KPL Y++L DLL+EF+  Y+   H L    +   + H     + + W+   ++  KL++E + K+L  ++
Sbjct:   69 PFIVNRGGLPVNEETWEQMWRHVARIHPDGEAVAKRIRGATDLPKIPIPTVPTYQPTTSIPHRLEAIQKYIRDLQYNHTGTQFFEIKKSRPLTALMDIAKEMTRESLPIKCLEAVILGIYLTNNMPSVERFPISFKTQFSGSHFRHIVLGIHSGGRFGALGISRREDLMFKPLEYRTLADLLQEFQTAYQGYWHTLRKVKIGQYVSHDPHSVEQIEWKHSVLDVDKLSKEELRKELERHT 308

[Close]

BLAST of Vasohibin-2 vs. TrEMBL
Match: A0A3B3H867 (Vasohibin 2 OS=Oryzias latipes OX=8090 GN=vash2 PE=4 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 2.110e-56
Identity = 95/265 (35.85%), Postives = 154/265 (58.11%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPRHWI 908
            + VN   FP++  TWD +     + +P  +  +  +   + L +  +P VP F    S+ + +  VQ ++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN + S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR +LM KPL +++L DL+ EF+  Y++ +H L    +   + H   V   + W+ L +N  +L  E + K+L  +   +  K   + S +    A  P+ W+
Sbjct:   65 FYVNRSGFPIDSSTWDRMWTHVAALHPEGQEMVTRIRNASYLPKHPVPAVPTFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHGRDMKMK---VLSGEETSRAQHPQRWL 326

[Close]

BLAST of Vasohibin-2 vs. TrEMBL
Match: A0A3B3CMW2 (Vasohibin 2 OS=Oryzias melastigma OX=30732 PE=4 SV=1)

HSP 1 Score: 196.052 bits (497), Expect = 3.059e-56
Identity = 91/239 (38.08%), Postives = 144/239 (60.25%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN G FP+   TWD + +   + +P  +  +  +     L +  +P VP F    S+ + +  VQ ++  L+YN+TG QFF++ K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN L ++ERF I F +QF G  + H+VLG+Y N R+GS+G+SRR +LM KPL +++L DL+ EF+  Y + +H L    +   + H   V   + W+ L +N  +L  E + K+L  + 
Sbjct:   63 FYVNRGGFPIEGSTWDRMWSHVAAVHPEGQEMVTRIRNAAFLPKHPVPAVPTFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEVKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGLTTLERFPISFKTQFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYRKYQHSLTKVKIGLYVPHDPHVFQPIEWKYLVLNVSRLGAEEMKKELEKHG 301

[Close]

BLAST of Vasohibin-2 vs. TrEMBL
Match: A0A3B1IP69 (Vasohibin 1 OS=Astyanax mexicanus OX=7994 GN=VASH1 PE=4 SV=1)

HSP 1 Score: 196.052 bits (497), Expect = 4.242e-56
Identity = 91/240 (37.92%), Postives = 150/240 (62.50%), Query Frame = 3

Query:  111 SYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
             +++N G  P+N  TW+++       +P      K +   T+L +  +P VP +    SI +++  +Q ++  L+YN+TG QFF+I K + + +LMD AK++   SLPIKCLEA+ILGIYLTN + SVERF I F +QF G  ++HIVLG+++  RFG++G+SRR +LMYKPL +++L DLL+E++  Y+   H L    +   + H     + + W+   ++  KL++E + K+L  ++
Sbjct:   69 PFIINRGGLPVNEETWEQMWRHVARIHPDGEVVGKRIRGVTDLPKIPIPTVPTYQPTTSIPQRLEAIQKYIRDLQYNHTGTQFFEIKKSRPLTALMDIAKEMTRESLPIKCLEAVILGIYLTNSMPSVERFPISFKTQFSGSHFRHIVLGIHSGGRFGALGISRREDLMYKPLEFRTLADLLQEYQTAYQGYWHTLRKVKIGQYVSHDPHSVEQIEWKHSVLDVDKLSKEELRKELERHT 308

[Close]

BLAST of Vasohibin-2 vs. TrEMBL
Match: A0A0S7KP44 (VASH2 (Fragment) OS=Poeciliopsis prolifica OX=188132 GN=VASH2 PE=4 SV=1)

HSP 1 Score: 193.356 bits (490), Expect = 6.536e-56
Identity = 90/244 (36.89%), Postives = 146/244 (59.84%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISH 845
            + VN   FP+   TW+ + +   + +P  +  +  +    NL ++ +P +P F    S  + +  VQ+++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILG+YLTN L S+ERF I F +QF G  + H+VLG+Y N R+GS+G+SRR +LM KPL +++L +L+ EF+  Y+  +H L    +   + H   V   + W+ L +N  +L  + + K L  +    SH
Sbjct:   61 FYVNRNGFPIESVTWERMWSHVAAVHPEGQEMVDRIRNAANLPKQAVPSIPTFKPSMSAPDWLVAVQNYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGVYLTNGLTSLERFPISFKTQFSGHCFHHVVLGVYCNGRYGSLGMSRRPDLMDKPLSHRTLSELVAEFESSYKRYQHTLKKVKIGLYVPHDPHVFQPIEWKYLVLNTTRLGAQEMRKDLEKHGRDFSH 304

[Close]

BLAST of Vasohibin-2 vs. Ensembl Cavefish
Match: VASH1 (vasohibin 1 [Source:NCBI gene;Acc:103022300])

HSP 1 Score: 196.052 bits (497), Expect = 1.607e-59
Identity = 91/240 (37.92%), Postives = 150/240 (62.50%), Query Frame = 3

Query:  111 SYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
             +++N G  P+N  TW+++       +P      K +   T+L +  +P VP +    SI +++  +Q ++  L+YN+TG QFF+I K + + +LMD AK++   SLPIKCLEA+ILGIYLTN + SVERF I F +QF G  ++HIVLG+++  RFG++G+SRR +LMYKPL +++L DLL+E++  Y+   H L    +   + H     + + W+   ++  KL++E + K+L  ++
Sbjct:   69 PFIINRGGLPVNEETWEQMWRHVARIHPDGEVVGKRIRGVTDLPKIPIPTVPTYQPTTSIPQRLEAIQKYIRDLQYNHTGTQFFEIKKSRPLTALMDIAKEMTRESLPIKCLEAVILGIYLTNSMPSVERFPISFKTQFSGSHFRHIVLGIHSGGRFGALGISRREDLMYKPLEFRTLADLLQEYQTAYQGYWHTLRKVKIGQYVSHDPHSVEQIEWKHSVLDVDKLSKEELRKELERHT 308

[Close]

BLAST of Vasohibin-2 vs. Ensembl Cavefish
Match: VASH1 (vasohibin 1 [Source:NCBI gene;Acc:103022300])

HSP 1 Score: 185.267 bits (469), Expect = 3.920e-55
Identity = 91/261 (34.87%), Postives = 151/261 (57.85%), Query Frame = 3

Query:  111 SYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQK---------------------GLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
             +++N G  P+N  TW+++       +P      K +   T+L ++                      +P VP +    SI +++  +Q ++  L+YN+TG QFF+I K + + +LMD AK++   SLPIKCLEA+ILGIYLTN + SVERF I F +QF G  ++HIVLG+++  RFG++G+SRR +LMYKPL +++L DLL+E++  Y+   H L    +   + H     + + W+   ++  KL++E + K+L  ++
Sbjct:   69 PFIINRGGLPVNEETWEQMWRHVARIHPDGEVVGKRIRGVTDLPKEMRTFCLADFALWLFFDTSCWIPIPTVPTYQPTTSIPQRLEAIQKYIRDLQYNHTGTQFFEIKKSRPLTALMDIAKEMTRESLPIKCLEAVILGIYLTNSMPSVERFPISFKTQFSGSHFRHIVLGIHSGGRFGALGISRREDLMYKPLEFRTLADLLQEYQTAYQGYWHTLRKVKIGQYVSHDPHSVEQIEWKHSVLDVDKLSKEELRKELERHT 329

[Close]

BLAST of Vasohibin-2 vs. Ensembl Cavefish
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:103025056])

HSP 1 Score: 181.415 bits (459), Expect = 6.372e-54
Identity = 86/239 (35.98%), Postives = 144/239 (60.25%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN   FP+   TW+ + +     +P  +  +  +    +L ++ +P VP F    S+ + +  VQ+++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN L S+ERF I F +QF G  + H+VLG+Y N R+G++G+SRR++LM K L +++L +L+ EF+  Y   +H +    +   + H+  V   + W+ L +N  +   E + K+L  + 
Sbjct:   66 FYVNRTGFPIESVTWERMWSHVAKVHPDGQEMVDRIRNAAHLPKQPVPLVPNFKPSMSVPDWLHAVQNYMKNLQYNHTGTQFFEIRKTRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSLERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDKSLSFRTLSELVFEFEDSYRRYQHTIKKVKIGLYVPHNPHVFQPIEWKYLVLNPCRQGREDMRKELEKHG 304

[Close]

BLAST of Vasohibin-2 vs. Ensembl Cavefish
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:103025056])

HSP 1 Score: 156.377 bits (394), Expect = 2.446e-44
Identity = 86/244 (35.25%), Postives = 139/244 (56.97%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSIL-----SLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN   FP+   TW+ + +     +P D  ++ D ++    + K +P VP F    S+ + +  VQ+++  L+Y     Q    NK KS L      LM+ A+++I  SLPIKCLEA+ILGIYLTN L S+ERF I F +QF G  + H+VLG+Y N R+G++G+SRR++LM K L +++L +L+ EF+  Y   +H +    +   + H+  V   + W+ L +N  +   E + K+L  + 
Sbjct:   66 FYVNRTGFPIESVTWERMWSHVAKVHP-DGQEMVDRIRNAAHLPKPVPLVPNFKPSMSVPDWLHAVQNYMKNLQYPSHETQ----NKDKSFLLTIGEVLMETAREMIRESLPIKCLEAVILGIYLTNGLTSLERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDKSLSFRTLSELVFEFEDSYRRYQHTIKKVKIGLYVPHNPHVFQPIEWKYLVLNPCRQGREDMRKELEKHG 304

[Close]

BLAST of Vasohibin-2 vs. Ensembl Sea Lamprey
Match: vash2 (vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355])

HSP 1 Score: 162.925 bits (411), Expect = 7.598e-49
Identity = 78/202 (38.61%), Postives = 121/202 (59.90%), Query Frame = 3

Query:  243 QKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHK 848
            Q   P VP F     I E++  VQ ++ +L+YN+TG QFF+I K + ++ LMD A++++  SLPIKCLEA+ILGI+LTN +  VERF + F SQF G  ++H+VL        GS+G+SRR +LM+K L ++SLYDL+ +F++ Y    H +    +  S+ H +   + + W  L ++ L+        +L  +S  I  K
Sbjct:    1 QPPFPAVPTFRPSMPIPERLLAVQIYMRELQYNHTGTQFFEIRKSRPLVGLMDAAREMVQESLPIKCLEAVILGIHLTNGIPGVERFPLSFKSQFCGRTFRHVVL--------GSLGMSRRPDLMHKQLTFRSLYDLIADFQEAYRGYLHTVTRIKVGLSVPHDSQSFETIAWGHLTLDTLRTGAAETRSRLERHSRDIRCK 194

[Close]

BLAST of Vasohibin-2 vs. Ensembl Sea Lamprey
Match: VASH1 (vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964])

HSP 1 Score: 125.176 bits (313), Expect = 2.827e-34
Identity = 59/196 (30.10%), Postives = 108/196 (55.10%), Query Frame = 3

Query:  243 QKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            Q  +P +P      ++ +++  +Q ++  L+YN+TG QFF+I K + I  LMD A+ ++  +L      +  L  YLTN L  VERF + F ++F G  ++H+VLG+    R+G++GLSRR  LM+K   +  L  L+ +F++ Y   +H +    +   + H       V W+ L ++  +L+ E + + L+ ++
Sbjct:    1 QVPVPSLPTLLPAVAMLDRLKAIQKYMMDLQYNHTGTQFFEIRKNRPIAGLMDLARDMVREALACNLCASNTLNCYLTNGLPGVERFPLSFRTRFGGSAFRHVVLGVCVGGRYGALGLSRRPELMFKAATHAGLAPLVADFRQAYSSYRHAVTRLKVGLYVPHDPRSFQQVEWRHLVVDVSRLSGEELRRDLDKHA 196

[Close]

BLAST of Vasohibin-2 vs. Ensembl Nematostella
Match: EDO40230 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7P4])

HSP 1 Score: 167.162 bits (422), Expect = 1.838e-50
Identity = 86/216 (39.81%), Postives = 134/216 (62.04%), Query Frame = 3

Query:  189 NPVDRNKIKDLLKKTNLIQKGLPQVPVFHQ--FQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            +P     +  + +K +L +      PVF      ++ EK+ L+Q +L QL+YN+TG Q F+I K++    LMD A++II  SLPIKCLEA+I+ +YLT+ +  ++RF IGF +QF    Y+H+VLG++AN ++G++GLSRR +LMYKPL +KSL DLL +F + Y    H +    +S  I H     + ++W+ L ++  KL+   + K L  YS
Sbjct:    9 HPDGMKMVYKIREKADLEEVPYASAPVFSPSCVLTVTEKLVLIQKYLQQLQYNHTGTQLFEIKKYRPYTGLMDTAREIIKESLPIKCLEAVIVSLYLTSSMSELQRFTIGFKTQFGSSIYRHVVLGVHANGKYGALGLSRRDDLMYKPLTFKSLCDLLNDFVESYGNYLHSVKKIKLSLPIVHDLHSCEKIHWKYLALSPAKLSASDMKKILEKYS 224

[Close]

BLAST of Vasohibin-2 vs. Ensembl Medaka
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:101157344])

HSP 1 Score: 196.438 bits (498), Expect = 7.943e-60
Identity = 95/265 (35.85%), Postives = 154/265 (58.11%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPRHWI 908
            + VN   FP++  TWD +     + +P  +  +  +   + L +  +P VP F    S+ + +  VQ ++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN + S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR +LM KPL +++L DL+ EF+  Y++ +H L    +   + H   V   + W+ L +N  +L  E + K+L  +   +  K   + S +    A  P+ W+
Sbjct:   65 FYVNRSGFPIDSSTWDRMWTHVAALHPEGQEMVTRIRNASYLPKHPVPAVPTFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHGRDMKMK---VLSGEETSRAQHPQRWL 326

[Close]

BLAST of Vasohibin-2 vs. Ensembl Medaka
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:101157344])

HSP 1 Score: 195.282 bits (495), Expect = 2.677e-59
Identity = 90/239 (37.66%), Postives = 144/239 (60.25%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN   FP++  TWD +     + +P  +  +  +   + L +  +P VP F    S+ + +  VQ ++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN + S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR +LM KPL +++L DL+ EF+  Y++ +H L    +   + H   V   + W+ L +N  +L  E + K+L  + 
Sbjct:   65 FYVNRSGFPIDSSTWDRMWTHVAALHPEGQEMVTRIRNASYLPKHPVPAVPTFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHG 303

[Close]

BLAST of Vasohibin-2 vs. Ensembl Medaka
Match: VASH1 (vasohibin 1 [Source:NCBI gene;Acc:101166671])

HSP 1 Score: 187.963 bits (476), Expect = 5.946e-57
Identity = 85/239 (35.56%), Postives = 148/239 (61.92%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN G  P++  TW+ +       +P      K++    +L +  +P VP +    +I +++  +Q ++ +L+YN+TG QFF+I K + + +LMD AK++   +LPIKCLEA+ILGIYLTN++  VERF + F SQ+ G  + HIVLG+Y+  RFG++G+SRR +LM+KP+ +++L DL++EF+  Y  + H L    +   + H     + + W+   I+  K+++E + K+L  ++
Sbjct:   31 FYVNRGGLPVDEETWERMWRHVARIHPNGEGLAKEIRSAADLPKIPIPSVPSYQLTTTIPQRLEAIQKYIRELQYNHTGTQFFEIKKSRPLTALMDIAKEMTREALPIKCLEAVILGIYLTNNMPGVERFPLSFKSQYSGNHFYHIVLGVYSGGRFGALGMSRREDLMFKPMEFRTLTDLVQEFEGAYRGNWHTLRKVKIGQYVSHDPHSVEQIEWKHSIIDIDKMSKEELRKELERHT 269

[Close]

BLAST of Vasohibin-2 vs. Ensembl Medaka
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:101157344])

HSP 1 Score: 176.407 bits (446), Expect = 2.576e-53
Identity = 81/193 (41.97%), Postives = 124/193 (64.25%), Query Frame = 3

Query:  252 LPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            +P VP F    S+ + +  VQ ++  L+YN+TG QFF+I K + +  LM+ A+++I  SLPIKCLEA+ILGIYLTN + S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR +LM KPL +++L DL+ EF+  Y++ +H L    +   + H   V   + W+ L +N  +L  E + K+L  + 
Sbjct:    4 VPAVPTFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHG 196

[Close]

BLAST of Vasohibin-2 vs. Ensembl Medaka
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:101157344])

HSP 1 Score: 115.161 bits (287), Expect = 1.278e-29
Identity = 64/239 (26.78%), Postives = 108/239 (45.19%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYS 830
            + VN   FP++  TWD +     + +P  +  +  +   + L +  +P VP F    S+ + +  VQ ++  L Y                                            LTN + S+ERF I F + F G  + H+VLG+Y N R+GS+G+SRR +LM KPL +++L DL+ EF+  Y++ +H L    +   + H   V   + W+ L +N  +L  E + K+L  + 
Sbjct:   33 FYVNRSGFPIDSSTWDRMWTHVAALHPEGQEMVTRIRNASYLPKHPVPAVPTFRASMSVSDWLLTVQKYMKALHY--------------------------------------------LTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHG 227

[Close]

BLAST of Vasohibin-2 vs. Planmine SMEST
Match: SMESG000069763.1 (SMESG000069763.1)

HSP 1 Score: 561.992 bits (1447), Expect = 0.000e+0
Identity = 275/275 (100.00%), Postives = 275/275 (100.00%), Query Frame = 3

Query:  105 MKSYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPRHWIHKVTWTQ 929
            MKSYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPRHWIHKVTWTQ
Sbjct:    1 MKSYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPRHWIHKVTWTQ 275

[Close]

BLAST of Vasohibin-2 vs. Planmine SMEST
Match: SMESG000069763.1 (SMESG000069763.1)

HSP 1 Score: 518.079 bits (1333), Expect = 0.000e+0
Identity = 258/275 (93.82%), Postives = 258/275 (93.82%), Query Frame = 3

Query:  105 MKSYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPRHWIHKVTWTQ 929
            MKSYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQF  I               YNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPRHWIHKVTWTQ
Sbjct:    1 MKSYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFHFIL--------------YNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPRHWIHKVTWTQ 261

[Close]

BLAST of Vasohibin-2 vs. Planmine SMEST
Match: SMESG000072424.1 (SMESG000072424.1)

HSP 1 Score: 177.948 bits (450), Expect = 1.989e-53
Identity = 103/265 (38.87%), Postives = 165/265 (62.26%), Query Frame = 3

Query:  114 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVP-VFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQ--LLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPR 899
            +++N G FPLN  ++  +I F+   N  D   I+ +LK+ ++ QK  P+VP + +    +  KI  +Q ++ +LEYN+TG QFF I   +++  LM+ AK+II+ SLPIKCLEA+ILGIYLTN +  +ERF IGF S F+G+ +KH+VLGLY+N  +G+IG+SRR  LM+KPL + SL DL+  + K Y++  H L    +  +I H +   + + W+  ++ +N L +N+    +++  YS  +  +    GS ++  L   PR
Sbjct:   13 FIINNGGFPLNEISFMRMIEFSKYLNSEDIESIESILKQ-HVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQ--FKEEIEKYSRKLRKQAAIRGSIQQHYLPFLPR 274

The following BLAST results are available for this feature:

BLAST of Vasohibin-2 vs. Ensembl Human
BLAST of Vasohibin-2 vs. Ensembl Celegans
BLAST of Vasohibin-2 vs. Ensembl Fly
BLAST of Vasohibin-2 vs. Ensembl Zebrafish
BLAST of Vasohibin-2 vs. Ensembl Xenopus
BLAST of Vasohibin-2 vs. Ensembl Mouse
BLAST of Vasohibin-2 vs. UniProt/SwissProt
BLAST of Vasohibin-2 vs. TrEMBL
BLAST of Vasohibin-2 vs. Ensembl Cavefish
BLAST of Vasohibin-2 vs. Ensembl Sea Lamprey
BLAST of Vasohibin-2 vs. Ensembl Yeast
BLAST of Vasohibin-2 vs. Ensembl Nematostella
BLAST of Vasohibin-2 vs. Ensembl Medaka
BLAST of Vasohibin-2 vs. Planmine SMEST

BLAST of Vasohibin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
VASH1	5.949e-52	34.31	vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964]	[more]
VASH2	1.186e-51	36.29	vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723]	[more]
VASH2	1.213e-47	39.90	vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723]	[more]
VASH2	1.213e-47	39.90	vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723]	[more]
VASH2	1.455e-44	40.66	vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723]	[more]

BLAST of Vasohibin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Vasohibin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Vasohibin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
VASH1	7.941e-58	37.66	vasohibin 1 [Source:NCBI gene;Acc:100001748]	[more]
vash2	6.121e-55	36.82	vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355]	[more]
vash2	2.345e-54	37.66	vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355]	[more]
vash2	2.345e-54	37.66	vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355]	[more]

BLAST of Vasohibin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
serinc5	3.935e-57	36.40	serine incorporator 5 [Source:Xenbase;Acc:XB-GENE-...	[more]
mios	3.697e-53	36.82	missing oocyte, meiosis regulator, homolog [Source...	[more]
mios	3.144e-24	25.94	missing oocyte, meiosis regulator, homolog [Source...	[more]

BLAST of Vasohibin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3


Match Name	E-value	Identity	Description
Vash1	6.181e-51	33.33	vasohibin 1 [Source:MGI Symbol;Acc:MGI:2442543]	[more]
Vash2	2.997e-50	35.86	vasohibin 2 [Source:MGI Symbol;Acc:MGI:2444826]	[more]
Vash2	2.997e-50	35.86	vasohibin 2 [Source:MGI Symbol;Acc:MGI:2444826]	[more]

BLAST of Vasohibin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4


Match Name	E-value	Identity	Description
sp\|Q7L8A9\|VASH1_HUMAN	2.857e-51	34.31	Tubulinyl-Tyr carboxypeptidase 1 OS=Homo sapiens O...	[more]
sp\|Q86V25\|VASH2_HUMAN	5.695e-51	36.29	Tubulinyl-Tyr carboxypeptidase 2 OS=Homo sapiens O...	[more]
sp\|Q8C1W1\|VASH1_MOUSE	4.323e-50	33.33	Tubulinyl-Tyr carboxypeptidase 1 OS=Mus musculus O...	[more]
sp\|Q8C5G2\|VASH2_MOUSE	2.096e-49	35.86	Tubulinyl-Tyr carboxypeptidase 2 OS=Mus musculus O...	[more]

BLAST of Vasohibin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3B4BVF1	6.816e-58	38.75	Vasohibin 1 OS=Pygocentrus nattereri OX=42514 GN=V...	[more]
A0A3B3H867	2.110e-56	35.85	Vasohibin 2 OS=Oryzias latipes OX=8090 GN=vash2 PE...	[more]
A0A3B3CMW2	3.059e-56	38.08	Vasohibin 2 OS=Oryzias melastigma OX=30732 PE=4 SV...	[more]
A0A3B1IP69	4.242e-56	37.92	Vasohibin 1 OS=Astyanax mexicanus OX=7994 GN=VASH1...	[more]
A0A0S7KP44	6.536e-56	36.89	VASH2 (Fragment) OS=Poeciliopsis prolifica OX=1881...	[more]

BLAST of Vasohibin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
VASH1	1.607e-59	37.92	vasohibin 1 [Source:NCBI gene;Acc:103022300]	[more]
VASH1	3.920e-55	34.87	vasohibin 1 [Source:NCBI gene;Acc:103022300]	[more]
vash2	6.372e-54	35.98	vasohibin 2 [Source:NCBI gene;Acc:103025056]	[more]
vash2	2.446e-44	35.25	vasohibin 2 [Source:NCBI gene;Acc:103025056]	[more]

BLAST of Vasohibin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
vash2	7.598e-49	38.61	vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355]	[more]
VASH1	2.827e-34	30.10	vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964]	[more]

BLAST of Vasohibin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Vasohibin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO40230	1.838e-50	39.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Vasohibin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
vash2	7.943e-60	35.85	vasohibin 2 [Source:NCBI gene;Acc:101157344]	[more]
vash2	2.677e-59	37.66	vasohibin 2 [Source:NCBI gene;Acc:101157344]	[more]
VASH1	5.946e-57	35.56	vasohibin 1 [Source:NCBI gene;Acc:101166671]	[more]
vash2	2.576e-53	41.97	vasohibin 2 [Source:NCBI gene;Acc:101157344]	[more]
vash2	1.278e-29	26.78	vasohibin 2 [Source:NCBI gene;Acc:101157344]	[more]

BLAST of Vasohibin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3


Match Name	E-value	Identity	Description
SMESG000069763.1	0.000e+0	100.00	SMESG000069763.1	[more]
SMESG000069763.1	0.000e+0	93.82	SMESG000069763.1	[more]
SMESG000072424.1	1.989e-53	38.87	SMESG000072424.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30014325 ID=SMED30014325|Name=Vasohibin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=972bp
TTTTATTGATTTTATTTGTTTATATTAAATAATTTAGAATTTTCTTTTTT
TAATTTTCAATACAAATAATTTAATGAATCACATCTAAAGATTGTTAGAG
AATAATGAAGTCTTATCTAGTAAATGAAGGAGATTTTCCTCTTAATGTTC
GAACCTGGGACGAATTAATAAATTTTGCCATTTCTAAAAATCCAGTTGAT
AGAAATAAAATAAAAGATTTATTGAAAAAAACAAACTTAATACAAAAAGG
ATTGCCTCAAGTTCCAGTTTTTCATCAATTCCAGTCGATCGAAGAAAAAA
TATTTTTAGTCCAAAGTTTCTTGAATCAACTGGAGTATAATTACACCGGA
ATGCAGTTTTTTAAAATTAATAAATTTAAGTCAATCTTGAGTCTAATGGA
CGAGGCCAAAAAGATAATCAGCAGCTCGTTGCCCATAAAATGCCTGGAGG
CGATTATTTTAGGAATATACCTCACAAATGATTTGGAAAGTGTAGAGAGA
TTCGGAATTGGGTTCATCTCACAGTTTGAAGGTGTCGAATATAAGCACAT
CGTATTGGGACTCTATGCAAATCAAAGGTTCGGATCAATTGGACTTAGTC
GCCGATCTAATTTAATGTATAAACCTTTAATATATAAATCGCTATATGAT
TTATTGAAAGAATTTAAAAAGTGCTACGAAGAGGATAAACACCTATTGTT
TGTCAACTATATGAGTAGTAGCATAGAGCACCATGCTTTTGTATCGGATG
TGGTGAATTGGCAACTGCTAAACATAAATTATTTGAAATTAAACGAAGAG
ACAATAGTAAAACAACTTAACAGTTACTCTGATTATATATCCCATAAGCC
TGAAAGAATGGGATCCAAAAAAAGGATTGAGCTTGCAGATAAACCTCGCC
ACTGGATTCACAAAGTCACCTGGACACAATAGTCATGAATTAAAAATGAA
TTTATAAAAGGTTTTGCATTTA

protein sequence of SMED30014325-orf-1

>SMED30014325-orf-1 ID=SMED30014325-orf-1|Name=SMED30014325-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=276bp
MKSYLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGL
PQVPVFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDE
AKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIV
LGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFV
NYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPE
RMGSKKRIELADKPRHWIHKVTWTQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000208	testis
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR028131	VASH1

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm

Vocabulary: **biological process**
Term	Definition
GO:0045765	regulation of angiogenesis

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR028131	Tubulinyl-Tyr carboxypeptidase	PFAM	PF14822	Vasohibin	coord: 4..243 e-value: 3.9E-79 score: 265.3
IPR028131	Tubulinyl-Tyr carboxypeptidase	PANTHER	PTHR15750	FAMILY NOT NAMED	coord: 35..259

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Vasohibin-2

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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