neural proliferation differentiation and control protein 1

Overview
Nameneural proliferation differentiation and control protein 1
Smed IDSMED30014321
Length (bp)1066
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of neural proliferation differentiation and control protein 1 (SMED30014321) t-SNE clustered cells

Violin plots show distribution of expression levels for neural proliferation differentiation and control protein 1 (SMED30014321) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of neural proliferation differentiation and control protein 1 (SMED30014321) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for neural proliferation differentiation and control protein 1 (SMED30014321) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014321

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30014321SMESG000034753.1 dd_Smed_v4_5338_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30014321SMESG000034753.1 dd_Smed_v4_5338_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30014321SMESG000034753.1 dd_Smed_v4_5338_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30014321SMESG000066467.1 SMESG000034753.1 OX_Smed_1.0.08771ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Category 4 cellSMED30014321SMESG000034753.1 dd_Smed_v4_5338_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Human
Match: NPDC1 (neural proliferation, differentiation and control 1 [Source:HGNC Symbol;Acc:HGNC:7899])

HSP 1 Score: 60.8474 bits (146), Expect = 7.768e-10
Identity = 41/127 (32.28%), Postives = 61/127 (48.03%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSNDE---CTVYECSGMGKMQNMEIRNPLF 707
             I+  CV+G        L +     C+ ++  +L +K   +  K   S         D++LA+SA+MYHYQ  +Q ++  E+       KE  T  SD  +E    TVYEC G+     ME+RNPLF
Sbjct:  187 LILAFCVAG-----AAALSVASLCWCRLQREIRLTQKADYATAKAPGSPAAPRISPGDQRLAQSAEMYHYQHQRQQMLCLERH--KEPPKELDTASSDEENEDGDFTVYECPGLAPTGEMEVRNPLF 306
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Human
Match: NPDC1 (neural proliferation, differentiation and control 1 [Source:HGNC Symbol;Acc:HGNC:7899])

HSP 1 Score: 60.8474 bits (146), Expect = 1.170e-9
Identity = 41/127 (32.28%), Postives = 61/127 (48.03%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSNDE---CTVYECSGMGKMQNMEIRNPLF 707
             I+  CV+G        L +     C+ ++  +L +K   +  K   S         D++LA+SA+MYHYQ  +Q ++  E+       KE  T  SD  +E    TVYEC G+     ME+RNPLF
Sbjct:  265 LILAFCVAG-----AAALSVASLCWCRLQREIRLTQKADYATAKAPGSPAAPRISPGDQRLAQSAEMYHYQHQRQQMLCLERH--KEPPKELDTASSDEENEDGDFTVYECPGLAPTGEMEVRNPLF 384
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Celegans
Match: cab-1 (pep chromosome:WBcel235:X:12199655:12205632:-1 gene:WBGene00000277.1 transcript:C23H4.1.4 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cab-1)

HSP 1 Score: 48.521 bits (114), Expect = 4.878e-6
Identity = 35/124 (28.23%), Postives = 58/124 (46.77%), Query Frame = 3 
Query:  345 IGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKAD--LNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFS 710
            +G V    +GL+ T+  G +     R+ +   + +Y       P    N     D  LA  AQ++ YQ +KQ +I  E A   + S G+    D +D  +  +VYEC G+    ++E+ NP F+
Sbjct:  305 VGTV--MCVGLIGTVAGGTYYYKNNRRTETPDDGEYAPYAGTGPGFRKNKGNKGDETLAYKAQLHQYQQAKQKIICGEDAPGIIESDGE----DGADEENNYSVYECPGLAPTGDIEVCNPNFA 422
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Celegans
Match: cab-1 (pep chromosome:WBcel235:X:12199656:12212946:-1 gene:WBGene00000277.1 transcript:C23H4.1.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cab-1)

HSP 1 Score: 48.521 bits (114), Expect = 4.878e-6
Identity = 35/124 (28.23%), Postives = 58/124 (46.77%), Query Frame = 3 
Query:  345 IGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKAD--LNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFS 710
            +G V    +GL+ T+  G +     R+ +   + +Y       P    N     D  LA  AQ++ YQ +KQ +I  E A   + S G+    D +D  +  +VYEC G+    ++E+ NP F+
Sbjct:  305 VGTV--MCVGLIGTVAGGTYYYKNNRRTETPDDGEYAPYAGTGPGFRKNKGNKGDETLAYKAQLHQYQQAKQKIICGEDAPGIIESDGE----DGADEENNYSVYECPGLAPTGDIEVCNPNFA 422
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Celegans
Match: cab-1 (pep chromosome:WBcel235:X:12199656:12213049:-1 gene:WBGene00000277.1 transcript:C23H4.1.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cab-1)

HSP 1 Score: 48.521 bits (114), Expect = 4.878e-6
Identity = 35/124 (28.23%), Postives = 58/124 (46.77%), Query Frame = 3 
Query:  345 IGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKAD--LNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFS 710
            +G V    +GL+ T+  G +     R+ +   + +Y       P    N     D  LA  AQ++ YQ +KQ +I  E A   + S G+    D +D  +  +VYEC G+    ++E+ NP F+
Sbjct:  305 VGTV--MCVGLIGTVAGGTYYYKNNRRTETPDDGEYAPYAGTGPGFRKNKGNKGDETLAYKAQLHQYQQAKQKIICGEDAPGIIESDGE----DGADEENNYSVYECPGLAPTGDIEVCNPNFA 422
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Celegans
Match: cab-1 (pep chromosome:WBcel235:X:12199656:12212901:-1 gene:WBGene00000277.1 transcript:C23H4.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cab-1)

HSP 1 Score: 48.521 bits (114), Expect = 4.878e-6
Identity = 35/124 (28.23%), Postives = 58/124 (46.77%), Query Frame = 3 
Query:  345 IGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKAD--LNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFS 710
            +G V    +GL+ T+  G +     R+ +   + +Y       P    N     D  LA  AQ++ YQ +KQ +I  E A   + S G+    D +D  +  +VYEC G+    ++E+ NP F+
Sbjct:  305 VGTV--MCVGLIGTVAGGTYYYKNNRRTETPDDGEYAPYAGTGPGFRKNKGNKGDETLAYKAQLHQYQQAKQKIICGEDAPGIIESDGE----DGADEENNYSVYECPGLAPTGDIEVCNPNFA 422
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Fly
Match: CG44247 (gene:FBgn0265182 transcript:FBtr0339097)

HSP 1 Score: 70.4774 bits (171), Expect = 5.987e-13
Identity = 50/142 (35.21%), Postives = 70/142 (49.30%), Query Frame = 3 
Query:  339 IIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDK-ISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQE-KADLNSQG-KERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDSISTIDNSVTPSKD 755
            +I G  +  T+GLL   +     + K     + P       +K +SPS         DRKLA+SAQMYHYQ  KQ +I  E +A   S G  +  +DD +   + TVYEC G+     ME++NPLF D     +   TPS +
Sbjct:  334 LIAGVSAAVTVGLLALGVTWFHNRHKAAADVEYPAYGVTGPNKDVSPSG--------DRKLAQSAQMYHYQHQKQQIIAMENQATDGSCGMSDVESDDDNEEGDYTVYECPGLAPTGEMEVKNPLFLD-----ETPATPSNN 462
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Fly
Match: CG44247 (gene:FBgn0265182 transcript:FBtr0339098)

HSP 1 Score: 70.4774 bits (171), Expect = 5.987e-13
Identity = 50/142 (35.21%), Postives = 70/142 (49.30%), Query Frame = 3 
Query:  339 IIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDK-ISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQE-KADLNSQG-KERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDSISTIDNSVTPSKD 755
            +I G  +  T+GLL   +     + K     + P       +K +SPS         DRKLA+SAQMYHYQ  KQ +I  E +A   S G  +  +DD +   + TVYEC G+     ME++NPLF D     +   TPS +
Sbjct:  334 LIAGVSAAVTVGLLALGVTWFHNRHKAAADVEYPAYGVTGPNKDVSPSG--------DRKLAQSAQMYHYQHQKQQIIAMENQATDGSCGMSDVESDDDNEEGDYTVYECPGLAPTGEMEVKNPLFLD-----ETPATPSNN 462
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Zebrafish
Match: npdc1b (neural proliferation, differentiation and control, 1b [Source:ZFIN;Acc:ZDB-GENE-140106-58])

HSP 1 Score: 76.2554 bits (186), Expect = 3.114e-15
Identity = 42/128 (32.81%), Postives = 75/128 (58.59%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLID-QEKADLNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDS 716
            F+++G V+    G+       C+++  QR  +   + DY +   I P+ +++G    D+KLA+SAQMYH+QL KQ ++  ++++D        ++D+ + + + TVYEC G+     ME++NPLF DS
Sbjct:  185 FLMVGSVAMVLTGV-------CWVR-MQRGCRLAQKVDYPAFGLIGPNSYDSGMS-GDKKLAQSAQMYHFQLQKQQMMSLKQRSDSKIPDSGATSDEENEDGDFTVYECPGLAPTGEMEVKNPLFDDS 303
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Zebrafish
Match: npdc1a (neural proliferation, differentiation and control, 1a [Source:ZFIN;Acc:ZDB-GENE-031204-31])

HSP 1 Score: 72.0182 bits (175), Expect = 8.130e-14
Identity = 44/141 (31.21%), Postives = 72/141 (51.06%), Query Frame = 3 
Query:  312 PSLSP---RDQFIIIGCVSGFTLGLLVTLIIG-CFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERS--TDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDS 716
            P +SP   RD  +++       +G +  +++  C+++  QR+ +   + DY +  + +     N T   D+ LA SAQMYHYQ  KQ ++  EK     +  E    +D+     + TVYEC G+     ME++NPLF DS
Sbjct:  162 PVISPNPSRDSLLVLMISLCIIVGAMALILVTVCWVRL-QRETRLAQKVDYPAFQEAA---NRNNTSSGDKTLAHSAQMYHYQHQKQQMLSMEKHKAEPKVSESGGHSDEETEEGDFTVYECPGLAPTGEMEVKNPLFDDS 298
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Mouse
Match: Npdc1 (neural proliferation, differentiation and control 1 [Source:MGI Symbol;Acc:MGI:1099802])

HSP 1 Score: 62.003 bits (149), Expect = 1.544e-10
Identity = 36/108 (33.33%), Postives = 57/108 (52.78%), Query Frame = 3 
Query:  399 CFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSND-ECTVYECSGMGKMQNMEIRNPLFSDSI 719
            C+ +  QR+ +   + DY +  K   S         D++LA SA+MYHYQ  +Q ++  E+     +  E ++ D ++ D + TVYEC G+     ME+RNPLF  S 
Sbjct:  153 CWCRL-QREIRLTQKADYAATAKGPTSPSTPRISPGDQRLAHSAEMYHYQHQRQQMLCLERHKEPPKELESASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHST 259
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Mouse
Match: Npdc1 (neural proliferation, differentiation and control 1 [Source:MGI Symbol;Acc:MGI:1099802])

HSP 1 Score: 62.003 bits (149), Expect = 2.563e-10
Identity = 36/108 (33.33%), Postives = 57/108 (52.78%), Query Frame = 3 
Query:  399 CFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSND-ECTVYECSGMGKMQNMEIRNPLFSDSI 719
            C+ +  QR+ +   + DY +  K   S         D++LA SA+MYHYQ  +Q ++  E+     +  E ++ D ++ D + TVYEC G+     ME+RNPLF  S 
Sbjct:  220 CWCRL-QREIRLTQKADYAATAKGPTSPSTPRISPGDQRLAHSAEMYHYQHQRQQMLCLERHKEPPKELESASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHST 326
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Mouse
Match: Npdc1 (neural proliferation, differentiation and control 1 [Source:MGI Symbol;Acc:MGI:1099802])

HSP 1 Score: 62.003 bits (149), Expect = 2.711e-10
Identity = 33/92 (35.87%), Postives = 49/92 (53.26%), Query Frame = 3 
Query:  447 DYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSND-ECTVYECSGMGKMQNMEIRNPLFSDSI 719
            DY +  K   S         D++LA SA+MYHYQ  +Q ++  E+     +  E ++ D ++ D + TVYEC G+     ME+RNPLF  S 
Sbjct:  226 DYAATAKGPTSPSTPRISPGDQRLAHSAEMYHYQHQRQQMLCLERHKEPPKELESASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHST 317
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. UniProt/SwissProt
Match: sp|Q64322|NPDC1_MOUSE (Neural proliferation differentiation and control protein 1 OS=Mus musculus OX=10090 GN=Npdc1 PE=2 SV=2)

HSP 1 Score: 62.003 bits (149), Expect = 1.896e-9
Identity = 33/92 (35.87%), Postives = 49/92 (53.26%), Query Frame = 3 
Query:  447 DYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSND-ECTVYECSGMGKMQNMEIRNPLFSDSI 719
            DY +  K   S         D++LA SA+MYHYQ  +Q ++  E+     +  E ++ D ++ D + TVYEC G+     ME+RNPLF  S 
Sbjct:  226 DYAATAKGPTSPSTPRISPGDQRLAHSAEMYHYQHQRQQMLCLERHKEPPKELESASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHST 317
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. UniProt/SwissProt
Match: sp|Q9NQX5|NPDC1_HUMAN (Neural proliferation differentiation and control protein 1 OS=Homo sapiens OX=9606 GN=NPDC1 PE=1 SV=2)

HSP 1 Score: 60.8474 bits (146), Expect = 3.730e-9
Identity = 41/127 (32.28%), Postives = 61/127 (48.03%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSNDE---CTVYECSGMGKMQNMEIRNPLF 707
             I+  CV+G        L +     C+ ++  +L +K   +  K   S         D++LA+SA+MYHYQ  +Q ++  E+       KE  T  SD  +E    TVYEC G+     ME+RNPLF
Sbjct:  187 LILAFCVAG-----AAALSVASLCWCRLQREIRLTQKADYATAKAPGSPAAPRISPGDQRLAQSAEMYHYQHQRQQMLCLERH--KEPPKELDTASSDEENEDGDFTVYECPGLAPTGEMEVRNPLF 306
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. TrEMBL
Match: A0A2G9S9R5 (Uncharacterized protein OS=Lithobates catesbeianus OX=8400 GN=AB205_0163180 PE=4 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 2.069e-16
Identity = 48/143 (33.57%), Postives = 75/143 (52.45%), Query Frame = 3 
Query:  300 GQIEPSLSPRDQFIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEK-DYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKA--DLNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDSI 719
            G  + +  P    +++G V    L  L+ L I     C+ R+  +L EK DY +  +  P  +   +   D+KLA++AQMYHYQ  KQ +I  EK   +L       ++D+ + + + TVYEC G+     ME++NPLF DS 
Sbjct:   42 GSPKTTRRPPGDALLLGVVVACALAGLMALTIAGVCWCRMRREIKLAEKTDYPAYRQSPPPPYEKTSSPGDKKLAQNAQMYHYQHQKQQMISMEKNKDELKHSDSAVTSDEENEDGDFTVYECPGLAPTGEMEVKNPLFDDST 184
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. TrEMBL
Match: A0A1L8F0W4 (Uncharacterized protein OS=Xenopus laevis OX=8355 GN=XELAEV_18041476mg PE=4 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 7.123e-16
Identity = 50/137 (36.50%), Postives = 73/137 (53.28%), Query Frame = 3 
Query:  315 SLSPRDQFIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEK-DYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSNDEC--TVYECSGMGKMQNMEIRNPLFSDS 716
            S  P    +I+G V G  +  LV L++     C+  + K+L +K DY S     P  +   T   D+KLA+SAQMYHYQ  KQ ++  EK    ++  + +    D N++   TVYEC G+     ME++NPLF DS
Sbjct:  149 STKPLSDALILGVVVGCAIAGLVALVVAGIYWCRMNREKKLAQKVDYTSYKSSPPPPYEK-TSPGDKKLAQSAQMYHYQHQKQQMLSMEKNKDETKHPDSALTSEDENEDGDFTVYECPGLAPTGEMEVKNPLFDDS 284
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. TrEMBL
Match: A0A3Q2QKB3 (Neural proliferation, differentiation and control, 1a OS=Fundulus heteroclitus OX=8078 PE=4 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 7.479e-16
Identity = 58/165 (35.15%), Postives = 82/165 (49.70%), Query Frame = 3 
Query:  252 VMPIFSQDSNKLVANSGQIEPSLSPRDQ------FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEK-DYNSLDKIS-PSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLID--QEKADLNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDS 716
             +P        L    G+  P + PR Q       II  CV   T+ +++  +  C++K   R   +L EK DY +    S P+   NG+ + D+ LAKSAQMYHYQ  KQ +I     K D  S   E ++D+ +     TVYEC G+     ME++NPLF DS
Sbjct:   36 TLPHTPTTQESLTGVDGRAGPLVVPRPQNDTTIVIIISLCVIVGTVAVILASV--CYVKL--RTESRLAEKVDYPAFKGPSLPATTANGSSVGDKNLAKSAQMYHYQHQKQQMISMGNPKPDPKSADTEVTSDEEEVAGGFTVYECPGLAPTGEMEVKNPLFDDS 196
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. TrEMBL
Match: W4YFM2 (Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 2.576e-15
Identity = 51/134 (38.06%), Postives = 72/134 (53.73%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISP-----SDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSNDE---CTVYECSGMGKMQNMEIRNPLFSD 713
             I++GCV+   +G+ +  I  C+ K  Q   K   E DY +     P     S  NNG    DRKLA+SAQMYHYQ  KQ +I  EK +     ++ S  DS+  +E    TVYEC G+     M+++NPLF++
Sbjct:  116 LIVVGCVAVAIIGVAIAFI--CWYKI-QTTSKAQNEADYPAYGVTGPGAQVTSSMNNG----DRKLAQSAQMYHYQHQKQQMIAMEKREKGDVARDASDYDSEEENEDGDLTVYECPGLAPTGEMQVKNPLFAE 242
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. TrEMBL
Match: A0A1S3K7P7 (neural proliferation differentiation and control protein 1 OS=Lingula unguis OX=7574 GN=LOC106179524 PE=4 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 2.598e-15
Identity = 55/145 (37.93%), Postives = 76/145 (52.41%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIG--CFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKA--DLNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDSISTIDNSVTPSKDN 758
            FI I  V+G +L  LV LI+   C+ K ++   K   E DY +     P    +     DRKLA+SAQMYHYQ  KQ +I  EKA  D+   G E  +D+ +   + TVYEC G+     ME++NPLFS+ ++         K N
Sbjct:  175 FIFIMLVAGCSLAGLVGLILAGVCWYKIRKSS-KAASEVDYPAYGVTGPQGREHVISPGDRKLAQSAQMYHYQHQKQQMIAMEKANGDMKHDGSEEDSDEENEEGDYTVYECPGLAPTGEMEVKNPLFSEDVTPTPGDKDKEKGN 318
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Cavefish
Match: npdc1b (neural proliferation differentiation and control protein 1-like [Source:NCBI gene;Acc:103026922])

HSP 1 Score: 75.485 bits (184), Expect = 6.486e-15
Identity = 48/147 (32.65%), Postives = 81/147 (55.10%), Query Frame = 3 
Query:  291 ANSGQIEPSLSP---RDQFIIIGCVSGFTLGLLVTLIIG-CFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSND-ECTVYECSGMGKMQNMEIRNPLFSDS 716
            A++ Q  P + P    +  +II       +G +  ++ G C+++  QR  +   + DY +   +SP  +++ T   D+KLA+SAQMYHYQ  KQ ++  ++ D     +  +T D ++ D + TVYEC G+     ME++NPLF DS
Sbjct:  172 ASAVQSAPIIIPYPSEEHSVIIMTGVCLMVGSVALVLAGVCWVR-MQRGSRLAQKVDYPAFGVMSPHSYDS-TSSGDKKLAQSAQMYHYQHQKQQMLSLKQRDETKIPESGATSDEENEDGDFTVYECPGLAPTGEMEVKNPLFDDS 316
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Cavefish
Match: npdc1a (neural proliferation differentiation and control protein 1-like [Source:NCBI gene;Acc:103027713])

HSP 1 Score: 72.0182 bits (175), Expect = 8.953e-14
Identity = 49/164 (29.88%), Postives = 84/164 (51.22%), Query Frame = 3 
Query:  243 NSFVMPIFSQDSNKLVANSGQIEPSLSP--RDQFIII---GCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKER-STDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDS 716
            ++   P  S+ +     +SG+ +P   P  RD  ++I    C+   T  L++  +  C+++  QR+ +   + DY +    + +  +      D+KLA SAQMYHYQ  KQ ++  +K     +  E  +T D ++  + TVYEC G+     ME++NPLF DS
Sbjct:  152 STSAQPHTSKTTEPHTDSSGRGKPIAVPLPRDSLLVILMSVCIIIGTAALILAAV--CWVRL-QREARLAQKVDYPAYPATA-TSSSTNASSGDKKLAHSAQMYHYQHQKQQMLSMDKHKAEPKVSESGATSDEETEGDFTVYECPGLAPTGEMEVKNPLFDDS 311
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Nematostella
Match: EDO36499 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF2])

HSP 1 Score: 54.6842 bits (130), Expect = 2.823e-8
Identity = 44/132 (33.33%), Postives = 60/132 (45.45%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKAD-LNSQG-----KERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSD 713
            FI+IGC      GL   L   C+ K      K + E +Y        +     TQ  D+KL  SA+MYHYQ +K  L   EKA  +  +G      +    D     + TVYEC G+    +M + NP+FSD
Sbjct:  261 FIVIGCSVAGIAGL--ALAGYCWYKL-HTTAKAVSETEYTGYGLKGSTKHPPPTQ-GDQKLDYSAEMYHYQQTKSQLAAMEKAGTVTPKGGALDDDDDENSDEGDEGDYTVYECPGLAPTGDMTVVNPMFSD 388
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Medaka
Match: npdc1a (neural proliferation differentiation and control protein 1 [Source:NCBI gene;Acc:101172509])

HSP 1 Score: 69.707 bits (169), Expect = 5.109e-13
Identity = 44/131 (33.59%), Postives = 66/131 (50.38%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEK-DYNSLDKISPSDF-NNGTQLMDRKLAKSAQMYHYQLSKQSLID--QEKADLNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDS 716
            F+++G V+       V + + C++K +     +L EK DY +      S      T + D  LAKSAQMYHY+  KQ +I     K +      E ++D+ +     TVYEC G+     ME++NPLF DS
Sbjct:  190 FVVMGTVA-------VIMAVACYVKLQTES--RLAEKVDYPAFKGTGVSSAKTTATPMGDNTLAKSAQMYHYKHQKQQMISMGNNKPEQKPVDSEFTSDEEEVGGGFTVYECPGLAPTGEMEVKNPLFDDS 311
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Medaka
Match: ENSORLT00000039373.1 (neural proliferation, differentiation and control 1 [Source:NCBI gene;Acc:101155607])

HSP 1 Score: 67.0106 bits (162), Expect = 3.613e-12
Identity = 47/163 (28.83%), Postives = 79/163 (48.47%), Query Frame = 3 
Query:  240 LNSFVMPIFSQDSNKLVANSGQIEPSLSPRDQFIIIGCVSGFTLGLLVTLIIGCFIKCKQ--RQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKER--STDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDS 716
            L+S   P  + +   +      I P  S    F+II  V     GL++ +   C+++ ++  R  +++    Y  +   +   F       D+KLA +AQMYHYQ  KQ ++  E+     +  +   STD+ + + + TVYEC G+     ME++NPLF DS
Sbjct:  126 LSSSWAPPTTTNHTSIPPRDPIILPYPSSDRVFVIISSVFIAAGGLVLLVAGACWLRLQKGLRLTQKVDYPAYGLMRAQNICSFPG-----DKKLAHNAQMYHYQHQKQQMLSMERHRDEPKVPDSGASTDEENEDGDFTVYECPGLAPTGEMEVKNPLFDDS 283
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Medaka
Match: npdc1a (neural proliferation differentiation and control protein 1 [Source:NCBI gene;Acc:101172509])

HSP 1 Score: 52.373 bits (124), Expect = 3.101e-7
Identity = 36/116 (31.03%), Postives = 56/116 (48.28%), Query Frame = 3 
Query:  336 FIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEK-DYNSLDKISPSDF-NNGTQLMDRKLAKSAQMYHYQLSKQSLID--QEKADLNSQGKERSTDDSDSNDECTVYECSGMG 671
            F+++G V+       V + + C++K +     +L EK DY +      S      T + D  LAKSAQMYHY+  KQ +I     K +      E ++D+ +     TVYEC G+ 
Sbjct:  190 FVVMGTVA-------VIMAVACYVKLQTES--RLAEKVDYPAFKGTGVSSAKTTATPMGDNTLAKSAQMYHYKHQKQQMISMGNNKPEQKPVDSEFTSDEEEVGGGFTVYECPGLA 296
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Medaka
Match: ENSORLT00000034941.1 (neural proliferation, differentiation and control 1 [Source:NCBI gene;Acc:101155607])

HSP 1 Score: 50.8322 bits (120), Expect = 8.751e-7
Identity = 41/156 (26.28%), Postives = 73/156 (46.79%), Query Frame = 3 
Query:  315 SLSPRDQ-----------FIIIGCVSGFTLGLLVTLIIGCFIKCKQ--RQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKER--STDDSDSNDECTVYECSGMG-----KMQNMEIRNPLFSDSIS 722
            S+ PRD            F+II  V     GL++ +   C+++ ++  R  +++    Y  +   +   F       D+KLA +AQMYHYQ  KQ ++  E+     +  +   STD+ + + + TVYEC G+      +  ++ +  P  S S+S
Sbjct:  140 SIPPRDPIILPYPSSDRVFVIISSVFIAAGGLVLLVAGACWLRLQKGLRLTQKVDYPAYGLMRAQNICSFPG-----DKKLAHNAQMYHYQHQKQQMLSMERHRDEPKVPDSGASTDEENEDGDFTVYECPGLAPVSQPRSSSLSVHQPGVSQSLS 290
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Medaka
Match: ENSORLT00000040575.1 (neural proliferation, differentiation and control 1 [Source:NCBI gene;Acc:101155607])

HSP 1 Score: 50.447 bits (119), Expect = 1.073e-6
Identity = 41/156 (26.28%), Postives = 73/156 (46.79%), Query Frame = 3 
Query:  315 SLSPRDQ-----------FIIIGCVSGFTLGLLVTLIIGCFIKCKQ--RQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKER--STDDSDSNDECTVYECSGMG-----KMQNMEIRNPLFSDSIS 722
            S+ PRD            F+II  V     GL++ +   C+++ ++  R  +++    Y  +   +   F       D+KLA +AQMYHYQ  KQ ++  E+     +  +   STD+ + + + TVYEC G+      +  ++ +  P  S S+S
Sbjct:  139 SIPPRDPIILPYPSSDRVFVIISSVFIAAGGLVLLVAGACWLRLQKGLRLTQKVDYPAYGLMRAQNICSFPG-----DKKLAHNAQMYHYQHQKQQMLSMERHRDEPKVPDSGASTDEENEDGDFTVYECPGLAPVSQPRSSSLSVHQPGVSQSLS 289
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Planmine SMEST
Match: SMESG000034753.1 (SMESG000034753.1)

HSP 1 Score: 413.305 bits (1061), Expect = 6.269e-147
Identity = 202/203 (99.51%), Postives = 203/203 (100.00%), Query Frame = 3 
Query:  156 MDCMTISLGNGIYQSLKLNYLAYLGIYVLNSFVMPIFSQDSNKLVANSGQIEPSLSPRDQFIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDSISTIDNSVTPSKDNAK 764
            MDCMTISLGNGIYQSLKLNYL+YLGIYVLNSFVMPIFSQDSNKLVANSGQIEPSLSPRDQFIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDSISTIDNSVTPSKDNAK
Sbjct:    1 MDCMTISLGNGIYQSLKLNYLSYLGIYVLNSFVMPIFSQDSNKLVANSGQIEPSLSPRDQFIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYNSLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDSISTIDNSVTPSKDNAK 203
[Close]
BLAST of neural proliferation differentiation and control protein 1 vs. Planmine SMEST
Match: SMESG000059206.1 (SMESG000059206.1)

HSP 1 Score: 71.633 bits (174), Expect = 3.839e-14
Identity = 39/75 (52.00%), Postives = 50/75 (66.67%), Query Frame = 3 
Query:  492 GTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGKERSTDDS---DSNDECTVYECSGMGKMQNMEIRNPLF 707
            G+   D+KLA+SAQMYHYQ  KQ +I  EKAD N +  E S D+S   D+ D+ TVYEC GM     +E++NPLF
Sbjct:  160 GSNSGDKKLAQSAQMYHYQHQKQQMIALEKADSNLR-NEASDDESEPDDAVDDFTVYECPGMAMGGELEVKNPLF 233
The following BLAST results are available for this feature:
BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
NPDC17.768e-1032.28neural proliferation, differentiation and control ... [more]
NPDC11.170e-932.28neural proliferation, differentiation and control ... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
cab-14.878e-628.23pep chromosome:WBcel235:X:12199655:12205632:-1 gen... [more]
cab-14.878e-628.23pep chromosome:WBcel235:X:12199656:12212946:-1 gen... [more]
cab-14.878e-628.23pep chromosome:WBcel235:X:12199656:12213049:-1 gen... [more]
cab-14.878e-628.23pep chromosome:WBcel235:X:12199656:12212901:-1 gen... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG442475.987e-1335.21gene:FBgn0265182 transcript:FBtr0339097[more]
CG442475.987e-1335.21gene:FBgn0265182 transcript:FBtr0339098[more]
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
npdc1b3.114e-1532.81neural proliferation, differentiation and control,... [more]
npdc1a8.130e-1431.21neural proliferation, differentiation and control,... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Npdc11.544e-1033.33neural proliferation, differentiation and control ... [more]
Npdc12.563e-1033.33neural proliferation, differentiation and control ... [more]
Npdc12.711e-1035.87neural proliferation, differentiation and control ... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q64322|NPDC1_MOUSE1.896e-935.87Neural proliferation differentiation and control p... [more]
sp|Q9NQX5|NPDC1_HUMAN3.730e-932.28Neural proliferation differentiation and control p... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2G9S9R52.069e-1633.57Uncharacterized protein OS=Lithobates catesbeianus... [more]
A0A1L8F0W47.123e-1636.50Uncharacterized protein OS=Xenopus laevis OX=8355 ... [more]
A0A3Q2QKB37.479e-1635.15Neural proliferation, differentiation and control,... [more]
W4YFM22.576e-1538.06Uncharacterized protein OS=Strongylocentrotus purp... [more]
A0A1S3K7P72.598e-1537.93neural proliferation differentiation and control p... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
npdc1b6.486e-1532.65neural proliferation differentiation and control p... [more]
npdc1a8.953e-1429.88neural proliferation differentiation and control p... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO364992.823e-833.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npdc1a5.109e-1333.59neural proliferation differentiation and control p... [more]
ENSORLT00000039373.13.613e-1228.83neural proliferation, differentiation and control ... [more]
npdc1a3.101e-731.03neural proliferation differentiation and control p... [more]
ENSORLT00000034941.18.751e-726.28neural proliferation, differentiation and control ... [more]
ENSORLT00000040575.11.073e-626.28neural proliferation, differentiation and control ... [more]
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BLAST of neural proliferation differentiation and control protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000034753.16.269e-14799.51SMESG000034753.1[more]
SMESG000059206.13.839e-1452.00SMESG000059206.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014321 ID=SMED30014321|Name=neural proliferation differentiation and control protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1066bp
CAAAATCATTCTTTAGAAACACACCTTGGTACTACTGCGATTATTATAAA
ATTGAATTATAAAGAAATTTATATTGATTTTCTTAAAATTTCCATGTATT
GTCAAAATCCTACTGTCAAAATCCCTGGTCAATAATTTATCGATCGTGAT
AAAAAATGGATTGTATGACAATAAGTTTAGGCAATGGAATTTATCAGTCT
CTAAAATTGAATTATTTAGCGTACCTAGGAATATATGTTTTAAATTCTTT
TGTGATGCCAATATTTTCTCAAGATTCAAATAAACTAGTAGCAAATTCTG
GTCAAATCGAACCTTCACTTAGTCCCAGGGATCAATTTATTATTATTGGT
TGTGTATCTGGGTTCACTTTAGGACTTTTGGTAACTTTAATTATTGGATG
CTTTATAAAATGCAAACAAAGACAGCCGAAGCAGCTGCCAGAAAAAGATT
ACAATTCACTGGACAAGATATCGCCATCGGATTTCAATAACGGGACACAG
CTAATGGACCGGAAATTGGCTAAATCCGCTCAAATGTATCATTATCAATT
GAGTAAGCAGAGCCTGATTGATCAAGAAAAAGCAGATTTGAATAGTCAGG
GTAAAGAAAGATCAACAGATGACTCAGATTCTAATGATGAGTGCACAGTT
TATGAGTGTTCTGGAATGGGAAAGATGCAAAATATGGAAATTCGTAATCC
GTTATTTTCTGACTCGATATCTACTATAGATAACAGTGTAACACCATCCA
AAGATAACGCGAAATAATTTACGTTGCAAAAAATTGCTGTTGTAGTTCAA
ATTTTACCTCATTTATCCGACTGTGGCTCTGGATTTAGATACAAATGGTG
ATAAATTGTAAATTATCTATTTTTATAATTGAGTAGAACCATTCTTATTT
GAAAAAAAAATATTTTACCTATATGATTTTGAGTGATCGTTTTGCTTATG
GTGCTGGAATTAATGATGGTGGTAAATTTCGGTAATATAACGTTGGGACT
GAGTTCCTTGCATTCAATATTCTAGCAAAGATGTTCGTAATAAATTATTC
TGTGATTTAAAAATAA
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protein sequence of SMED30014321-orf-1

>SMED30014321-orf-1 ID=SMED30014321-orf-1|Name=SMED30014321-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=204bp
MDCMTISLGNGIYQSLKLNYLAYLGIYVLNSFVMPIFSQDSNKLVANSGQ
IEPSLSPRDQFIIIGCVSGFTLGLLVTLIIGCFIKCKQRQPKQLPEKDYN
SLDKISPSDFNNGTQLMDRKLAKSAQMYHYQLSKQSLIDQEKADLNSQGK
ERSTDDSDSNDECTVYECSGMGKMQNMEIRNPLFSDSISTIDNSVTPSKD
NAK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000018Category 4 cell
PLANA:0000418head
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR009635NPDC1
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009635Neural proliferation differentiation control-1PFAMPF06809NPDC1coord: 70..188
e-value: 5.2E-15
score: 55.3
IPR009635Neural proliferation differentiation control-1PANTHERPTHR23352NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN-1 NPDC-1 PROTEINcoord: 41..189
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 179..203
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 180..203
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 142..162
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 144..159
NoneNo IPR availableTMHMMTMhelixcoord: 61..83
NoneNo IPR availableTMHMMTMhelixcoord: 20..37