Degenerin unc-8

Overview
NameDegenerin unc-8
Smed IDSMED30014274
Length (bp)1559
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Degenerin unc-8 (SMED30014274) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Degenerin unc-8 (SMED30014274) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30014274

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30014274SMESG000069054.1 dd_Smed_v4_19835_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30014274SMESG000069054.1 dd_Smed_v4_19835_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: S5W2R2 (Asic OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 539.65 bits (1389), Expect = 0.000e+0
Identity = 264/496 (53.23%), Postives = 375/496 (75.60%), Query Frame = 2 
Query:    8 MIELVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFY 1495
            MI+L++SSTIHGI HI+SA  K+ K LWC+LF+ G+I IIVNI F+S+++ S PV+ISYTFEHEPF+WPDITFCNPT P+     S+ Y +W++  N+++ V   + ++T + Q+I   +E D+ELEERTIAM+S++P KL A  F+N++  +GY + H G+YF+K+ Q+++ K    D K LF++QIVQ++NNIPCHTFH+ KS I+    ++SL+F  + N +SY+IFNSSYT +S+FLYISN+DEI Q   I L+PG+NN++ L+QNRH Y GLRR CR++ F+ E+YD+L Q+ + + GSY+DCK+IVSQ+ +V  C CY+ FLPIFKN +GFPRLCLNA+ FS+ ++L+NAKCM+N +  + +S   R+ + N+C +++   C+ + Y++D RK++LV+LWSK  N +R   IK ++   F  NE+  DF E ++DNI+ LII R  E  DL+KEEREYPFSELLSD+GGLMGLWLG+SV+GLFEI+EF Y
Sbjct:    1 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTK-LNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFVY 495
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: A0A5J4NUF1 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0013022 PE=3 SV=1)

HSP 1 Score: 292.352 bits (747), Expect = 4.549e-87
Identity = 182/524 (34.73%), Postives = 272/524 (51.91%), Query Frame = 2 
Query:   17 LVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHM-HKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFL--PIFKNQTGFPR---LCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRK-HYNNQCLIFKLHKCDLLSYQM-DLRKDMLVELWSKVYNGKRLNSIKFMHSYYFG-------------------KNESKKDFNEV------MRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEF 1489
            L++ ST+HG++H+ +A  KL +  W  L + GI G   N+ F+  RY + PVL SY  E+E F+WPDIT CN  AP+ L    +  K W  + NQ+    + L   + LF  I    + +  ++   +  ++ +P + G    E  ++FV     + GI    +I  N     P  LK  F TQ++Q + N+PC+T  + H    +  N V S+  G++FN +SY I NSSY +  I L+IS+      D  I + PG+   LSL  +R      R  CR   +  EV+D      +   GS   C +IVSQ L+++ C CYSPFL  P+  N   F +   LC N + FS  ++  NA CM+ +YE ++ S  +        C  F+   CD + Y++ D+R+  +VELWS  YN  R   I F+ S +                     K+++ KD + +      MRDN   L + RK E  +L +EE EYP SEL+SD+GGLMGLW+G+SV+GLFEI+E 
Sbjct:   30 LLEHSTVHGLSHVSTAATKLGRITWFCLLLAGIAGFFTNLSFIIDRYLTRPVLTSYISEYEGFIWPDITLCNAMAPYSLHLHGRIPK-WQALRNQASAFAQKL--NSSLFASIDSQDQNEIAIQ--ALMYSTLSPPEYGVGEPEEFIQFVATDVGYQGIILTVEISGNMTHLNP-PLKKYFHTQVLQKRYNVPCYTLQLRHSLTAVQSNQVNSIGLGVKFNVESYRIINSSYASPYIDLFISHPGHAPHDDPIEMLPGYTLSLSLRMSRLRREPARLSCRTDFYTTEVFDPDLVTKRRVNGSATFCHRIVSQHLYLNSCHCYSPFLPYPVVYNHKLFSKMAILCFNMSRFSVAQINRNADCMLRIYERYQLSSVYNSVPEARACEQFRKPLCDDVEYKLSDIRRTAMVELWSNSYNEAR---IAFLTSSFQNLFSSDIPPEQLVSWLDSDTKDDNTKDNDSMPKILKYMRDNFGLLSVNRKSELGELVREELEYPLSELMSDVGGLMGLWIGISVIGLFEIVEL 544
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: A0A183A5V1 (Uncharacterized protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS2336 PE=3 SV=1)

HSP 1 Score: 284.263 bits (726), Expect = 6.775e-84
Identity = 174/547 (31.81%), Postives = 294/547 (53.75%), Query Frame = 2 
Query:   17 LVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQN-----NNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHM----HKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFL--PIFKNQT---GFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQ-CLIFK-LHKCDLLSYQMD-LRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEV-------------MRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLFS-------INACLNKKNKSRFS 1546
            L++ ST+HG++H+ +A+ ++ + +W +L++ G+ G   N+ F+  RY + PVL SY  +HE F+WPDIT CNP AP+ +  +++  K W ++  ++  V K + ++  LF  I ++++   E+  + +  ++ +P + G    +  ++FV   +  SGI+   ++ +     + PKT        F  Q++Q ++NIPC+T  +     + + L+ N V     GL+FN+DS+ I NSSY  R+I L+IS      +D+++ L  G+ + +S+S  R      R  CR   F  +++DA  +  +   GS + C ++VSQRL+++ C CYSPFL  P+        G P LC N + F+ T + +NAKCM +VY  +     +      Q C  F+    C+  SY  + LR+  ++ELWS   N  R   +       FG +  ++   ++             MR+N   + I RKF    L  EE EYP SELLSD+GGLMGLW+G+SV+GLFE++E     S       I  C + +++++ S
Sbjct:   33 LLEHSTVHGLSHVSTASSRIGRSIWLILWLAGVAGFFTNLSFIVSRYMTRPVLTSYKHDHESFIWPDITLCNPMAPYPVHLRNRTEK-WNELRLRATRVAKNISED--LFAAIDDAEQ--LEIAIQALLYSTISPEQFGVGEPQELIQFVAADKGRSGIHLTVEMYSTFTDLDAPKT------QYFHAQMLQKRHNIPCYTLQLAHVLSQEDCLSTNQVS---LGLKFNHDSFLIINSSYAPRNIDLFISLPGHFPEDESMELLSGYTHKVSVSMTRFIREPNRLPCRTDEFVAQMFDANLKTRREIVGSADFCHKLVSQRLYINNCGCYSPFLPYPVVDEHLLVHGQPVLCFNMSHFNITSIDQNAKCMYDVYTQYHDHSVYMNLPEAQYCETFRSTPPCESTSYMPESLRRTPIIELWSDTINEGRTAFLTSTFESVFGPDLPEERIRQLLNNSGNNSNMFTYMRNNFGMVTISRKFPRGTLTHEELEYPLSELLSDLGGLMGLWIGISVIGLFEVVELLAFVSLSMISALIERCYSSRSRTKCS 565
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: A0A4S2L913 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009406 PE=3 SV=1)

HSP 1 Score: 273.478 bits (698), Expect = 3.913e-80
Identity = 175/524 (33.40%), Postives = 279/524 (53.24%), Query Frame = 2 
Query:   17 LVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYL---DRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNS-VQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFL--PIFKNQTGF---PRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRK-HYNNQC-LIFKLHKCDLLSYQM-DLRKDMLVELWSKVYNGKRLNSIKFMHSYYFG----KNESKKDFN---------EVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLFSINA 1513
            L++ ST+HG++H+ SA+  + +  W VLF+ GI G  +N+  +  RY S PVL S   +H+ FVWPDIT CNP+AP+ +   DR  K    W+++ + +++V + +  E  LF  I E+ +   E++ + +  ++ +P   G  +    V FV     H GI    ++ + N       ++  F T I+Q + NIPC+T  + +    +    V+ +  GL+FN +S+ I N+SY + ++   IS    +  D+ I L PG+ + + L+  R      +R CR+  F  EV+DA         GS   C +I+SQ L++  C CYSPFL  P+  +   F   P LC N + F   +L +NAKCM N+ E ++    +       +C  +  +  C+ + +Q+   R+  L ELWS+ YN  RL+ +K      F     +N   K F+           +R+N   + IERK E  +L +E+ EYP +ELLSDIGGLMGLW+G+SV+GLFE+LE   L S+  
Sbjct:   72 LLEHSTVHGLSHVSSASSHVGRITWFVLFVAGITGFCINLSLIVSRYVSRPVLTSIFNDHDDFVWPDITICNPSAPYVVHLYDRHEK----WLRLRDWAKNVAQYIPSE--LFAAIDEADKV--EIKTQALMHSTMSPSDFGVGIPNETVNFVAADTGHYGIVLTVEL-DGNLTYLSAPMEQYFRTHILQKRYNIPCYTLQIEQGMPEDERKRVRKVALGLKFNIESHMIINTSYVSPTLDFIISRPGHMPHDEPIELLPGYMHYIGLNFQRFKREPSKRPCRNNVFDVEVFDANLATKYPVHGSATLCHRILSQNLYIKYCGCYSPFLPYPVIPSHPDFDDSPVLCFNMSRFKIEQLNQNAKCMFNLLEKYRDPVTYMNIPEARECEYLGSVPPCEDIEHQLIQTRRTPLWELWSEKYNDARLSFLKAAFQLVFEVDIVQNRLGKSFHINNDSEPALRYLRENFALITIERKVEKGELIREDLEYPLAELLSDIGGLMGLWIGISVIGLFEVLELLGLMSVTV 586
[Close]
BLAST of Degenerin unc-8 vs. TrEMBL
Match: A0A4E0RSD9 (Degenerin unc-8 OS=Fasciola hepatica OX=6192 GN=D915_000009 PE=3 SV=1)

HSP 1 Score: 266.544 bits (680), Expect = 6.913e-77
Identity = 168/536 (31.34%), Postives = 289/536 (53.92%), Query Frame = 2 
Query:   17 LVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPF--YLDRKSKAYKYWMQINNQ-SRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKP---LFSTQIVQIQNNIPCHTFHMHKSNILNPN---SVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLP---IFKNQTGF--PRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRK-HYNNQCLIFKLH-KCDLLSYQMD-LRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEV-------------MRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFY---LFSINACLNK 1525
            L++ ST+HG++H+ +A  ++ + +W +L++ G+ G   N+ F+  RY + PVL SY  +HE F+WPDIT CNP AP+  +L+ +S+ +    Q+    SR++         LF  I E+++   E+  + +  ++ +P++ GA+     V FV   +  +GI+   ++      TF     P    F  Q++Q + NIPC+T  + +  +LN     S + +  GL+FN+DS  I NSSY   +I L+IS    + +D+ + +  G+++ ++++  R      R  CR + F  +V+DA  +  +   GS + C +++SQRL++D C CYSPFLP   + ++   +  P LC N + F+ + +  NA+CM +VY  FK+   +        C  F+    C+ ++Y ++  R+  ++E W+   N  R   +       FG++  ++   ++             MR+N   + I RK     L  EE EYP SELLSD+GGLMGLW+G+SV+GLFE++E F    L  I+A L +
Sbjct:   34 LLEHSTVHGLSHVSTAGTRIGRSVWLILWMAGVAGFFTNLSFIVSRYMTRPVLTSYKHDHELFIWPDITLCNPMAPYPVHLNNRSEKWNLLHQLATAVSRNI------SGNLFATIDEAEQE--EVTVQALIHSTVSPMEFGANDPHELVHFVAVDKGQTGIHLTIEMD----ATFTNLDIPKHRYFHVQVLQKRYNIPCYTLRLDQ--VLNEEECASTKQVSLGLKFNHDSNLIINSSYAPFNIDLFISLPGHMPEDEPMEILSGYSHKVTVTMGRFTRERTRLPCRTEQFVTQVFDADLKTQREVVGSADFCLKLLSQRLYIDHCGCYSPFLPYPVMGQDHPLYQQPVLCFNMSHFNASGIDRNARCMYDVYTQFKEDFVYMNLPEAGYCETFRATPPCESINYVLESPRRTPIIEFWADTVNEARSAFVTSTFESVFGQDLPEERLKQMVNNSGNTSSLLFYMRNNFGLVKITRKLPRGTLTHEELEYPLSELLSDVGGLMGLWVGISVIGLFEVVELFAFVGLTVISALLER 555
[Close]
BLAST of Degenerin unc-8 vs. Ensembl Sea Lamprey
Match: asic1a (acid-sensing (proton-gated) ion channel 1a [Source:NCBI gene;Acc:791696])

HSP 1 Score: 49.2914 bits (116), Expect = 1.805e-6
Identity = 32/108 (29.63%), Postives = 57/108 (52.78%), Query Frame = 2 
Query: 1241 GKRLNSIKF---MHSYYFGKNESKKDFNEVMRDNIV--DLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLF---SINACLNKKNKSR 1540
            GK L+ +K      + Y  K  +K +  + +R+N++  D+  E    Y +  ++++ Y  + LL DIGG MGL++G S++ + EI ++ Y      +  C  K NK R
Sbjct:  387 GKELSMVKIPSKASAKYLAKKYNKTE--DYIRENVLVLDIFFEAALNY-ETIEQKKAYEVAGLLGDIGGQMGLFIGASILTILEIFDYLYEVLKDKVCKCRKKHNKKR 491
[Close]
BLAST of Degenerin unc-8 vs. Ensembl Sea Lamprey
Match: ASIC5 (acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537])

HSP 1 Score: 48.521 bits (114), Expect = 2.720e-6
Identity = 24/60 (40.00%), Postives = 40/60 (66.67%), Query Frame = 2 
Query: 1322 MRDNIVDLIIERKFEYSDL----FKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEF 1489
            MR+N++ + +     Y+DL     ++++  P S LLSDIGG +GL++G SV+ + E+LEF
Sbjct:  384 MRENLLSIDVA----YTDLNYALIQQQKTLPESVLLSDIGGQLGLFVGASVITIIEVLEF 439
[Close]
BLAST of Degenerin unc-8 vs. Ensembl Sea Lamprey
Match: ASIC5 (acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537])

HSP 1 Score: 48.521 bits (114), Expect = 2.753e-6
Identity = 24/60 (40.00%), Postives = 40/60 (66.67%), Query Frame = 2 
Query: 1322 MRDNIVDLIIERKFEYSDL----FKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEF 1489
            MR+N++ + +     Y+DL     ++++  P S LLSDIGG +GL++G SV+ + E+LEF
Sbjct:  394 MRENLLSIDVA----YTDLNYALIQQQKTLPESVLLSDIGGQLGLFVGASVITIIEVLEF 449
[Close]
BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000069054.1 (SMESG000069054.1)

HSP 1 Score: 1046.57 bits (2705), Expect = 0.000e+0
Identity = 517/517 (100.00%), Postives = 517/517 (100.00%), Query Frame = 2 
Query:    8 MIELVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLFSINACLNKKNKSRFSPKNI 1558
            MIELVKSSTIHGINHIYSANGKLAKFLWCVLFIFGIIGIIVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLFSINACLNKKNKSRFSPKNI
Sbjct:    1 MIELVKSSTIHGINHIYSANGKLAKFLWCVLFIFGIIGIIVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLFSINACLNKKNKSRFSPKNI 517
[Close]
BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000020604.1 (SMESG000020604.1)

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 273/498 (54.82%), Postives = 391/498 (78.51%), Query Frame = 2 
Query:    8 MIELVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLF 1501
            MI+L++SSTIHGI HIYSA GK++K LWC+LF+FG++GIIVNI FVS+++FS PV+ISYTFE+EPF+WPDITFCNPT P+  +  S+ Y YW++  NQ++ + + + +E+++ Q+I    + DFELEERTIAM++++P KLGA+ F+N++  +GY + H G+YF+K+ Q+++P  F  +LKPLF++Q +QI+NNIPCHTFH+ KS  L+   ++SL+F  +FN  SY++FNSSYT +SIFLYI+N++EI  +  I L+PG+NNI+ L+QNR+ +NG+RR CR K +K E+Y+AL Q+ +TF G+++DC QI SQR++V+ C CYSPFLPI+KN++GFPRLCLNA+ FS +++L N KC+++ Y +F+ +   +  Y ++C  +K   C+ +SY++D RK+MLV+LWSK  N +RL  +K ++ + F  NE+  DF   ++DNI+ LII R  EY DLFKEEREYPF+ELLSDIGGLMGLWLG+SVVGLFEI+EF YLF
Sbjct:    1 MIDLIQSSTIHGIGHIYSAPGKVSKGLWCILFLFGVVGIIVNIVFVSMKFFSNPVIISYTFEYEPFIWPDITFCNPTDPYAFEIDSEPYLYWIKTLNQTKPIAERVFRESEISQVIHSQNDNDFELEERTIAMSTADPEKLGANGFQNYLTRIGYVKAHRGLYFSKEYQSSSPSKFSENLKPLFTSQTIQIRNNIPCHTFHLDKSRFLSQRRIRSLIFRFKFNEKSYKMFNSSYTFQSIFLYINNKNEIPIENEIILTPGYNNIVQLTQNRYVHNGMRRPCRTKEYKVELYEALLQSTETFFGNFDDCNQITSQRMYVENCHCYSPFLPIYKNESGFPRLCLNASIFSLSEILNNTKCLIDTYNDFQSAPKIKAKYYSECREYKPIPCERISYKIDHRKEMLVDLWSKSANDRRLGIVKQIYYHVFETNETSSDFVHKVKDNIMQLIINRDSEYGDLFKEEREYPFAELLSDIGGLMGLWLGLSVVGLFEIVEFLYLF 498
[Close]
BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000011523.1 (SMESG000011523.1)

HSP 1 Score: 545.814 bits (1405), Expect = 0.000e+0
Identity = 267/498 (53.61%), Postives = 378/498 (75.90%), Query Frame = 2 
Query:    8 MIELVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLF 1501
            MI+L++SSTIHGI HI+SA  K+ K LWC+LF+ G+I IIVNI F+S+++ S PV+ISYTFEHEPF+WPDITFCNPT P+     S+ Y +W++  N+++ V   + ++T + Q+I   +E D+ELEERTIAM+S++P KL A  F+N++  +GY + H G+YF+K+ Q+++ K    D K LF++QIVQ++NNIPCHTFH+ KS I+    ++SL+F  + N +SY+IFNSSYT +S+FLYISN+DEI Q   I L+PG+NN++ L+QNRH Y GLRR CR++ F+ E+YD+L Q+ + + GSY+DCK+IVSQ+ +V  C CY+ FLPIFKN +GFPRLCLNA+ FS+ ++L+NAKCM+N +  + +S   R+ + N+C +++   C+ + Y++D RK++LV+LWSK  N +R   IK ++   F  NE+  DF E ++DNI+ LII R  E  DL+KEEREYPFSELLSD+GGLMGLWLG+SV+GLFEI+EFFYLF
Sbjct:    1 MIDLIQSSTIHGIGHIFSATNKIFKVLWCILFLVGVIAIIVNIVFISMKFLSNPVIISYTFEHEPFIWPDITFCNPTDPYAFTINSQPYLHWIETLNKTKRVAGKVARQTSMSQLIHSRRENDYELEERTIAMSSADPAKLQATAFQNYLYRIGYIKAHKGLYFSKEFQSSSTK-LNEDWKSLFTSQIVQMRNNIPCHTFHLDKSRIVKQKFIKSLLFRFKLNEESYKIFNSSYTFQSMFLYISNKDEIPQSNEIILTPGYNNVVQLTQNRHSYTGLRRTCRNEKFEAELYDSLLQSTEKYSGSYDDCKKIVSQQKYVKYCNCYNSFLPIFKNSSGFPRLCLNASIFSEAEVLKNAKCMINTFRKYAESDKARRRFYNRCKMYRPIPCNKVLYKIDHRKEILVDLWSKSTNDRRREIIKTLYLKTFQTNETSLDFVEKVKDNIMQLIINRDNESGDLYKEEREYPFSELLSDVGGLMGLWLGLSVIGLFEIVEFFYLF 497
[Close]
BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000017678.1 (SMESG000017678.1)

HSP 1 Score: 543.502 bits (1399), Expect = 0.000e+0
Identity = 267/503 (53.08%), Postives = 363/503 (72.17%), Query Frame = 2 
Query:    8 MIELVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLFSINAC 1516
            MIE+++SSTIHG++HI+ A  ++ K LW  LFIFGIIGI VNI FV I+YFS PVLIS+  +HEPF+WPD+TFC PTAP+Y    S+AY +W  +  ++R +V+ L  ET++F+II   + TD+ELEERTIAM+S++P KL  + F  H+  + + +   GIY++ D       +F  DLKPLF+  +VQI+NNIPC TFH+ KS  LN N ++S+ F L+FN +SY +FNSSY  RS+FLYI+NR+ I     I L+PGFNNI+SLSQ+R+ Y G+ RKCR+K F+ E+YD L Q+  TFEG Y+DCK++ SQ+LFV  CKCYSPFLPI+KN+TG PR+CLNATF+S+ +++ NAKCM +VY  F+    FR HY  +C  ++  KC+ + Y+++  K++ VE WS + N +R   +K + SYY  +    K++ E MRDN + + I R+F+  DL+KEE EYPFSELLSDIGGLMGLWLGMSVVGLFEI E  YL+  N C
Sbjct:    1 MIEILQSSTIHGVSHIHGAKSQITKVLWIFLFIFGIIGIFVNIVFVIIKYFSNPVLISHKLDHEPFIWPDVTFCKPTAPYYFGENSQAYTHWSHVFWRTRRIVERLANETEVFKIINGKRNTDYELEERTIAMSSADPYKLKTNDFRYHIMAIYFNKMQRGIYYHIDNSGIAVTSFAEDLKPLFTAPLVQIRNNIPCFTFHIDKSKFLNQNQIKSISFYLKFNLESYLLFNSSYLHRSVFLYITNRNGIPHKNEILLAPGFNNIVSLSQSRYEYRGVLRKCRNKIFETELYDGLLQSTSTFEGHYDDCKKVESQKLFVGICKCYSPFLPIYKNETGPPRICLNATFYSEDEIVRNAKCMTDVYTKFQSYKAFRNHYRLKCQDYRFIKCNEVKYKIEKDKELFVEFWSGLTNQRRNELLKKV-SYYLMEKFDIKNYFERMRDNFIGITINREFQKGDLYKEEYEYPFSELLSDIGGLMGLWLGMSVVGLFEIFELMYLYLKNLC 502
[Close]
BLAST of Degenerin unc-8 vs. Planmine SMEST
Match: SMESG000069546.1 (SMESG000069546.1)

HSP 1 Score: 508.449 bits (1308), Expect = 5.817e-177
Identity = 262/507 (51.68%), Postives = 358/507 (70.61%), Query Frame = 2 
Query:    8 MIELVKSSTIHGINHIYSANGKLAKFLWCVLXXXXXXXXXVNICFVSIRYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQSRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFENHVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCHTFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDEIQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNVKTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFSKTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLRKDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLIIERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLFSINACLNKK 1528
            MIE+++SSTIHG++HI+ A  ++ K LW +LFI G+IGI VNI FV +RYFS PVLIS   +HEPF+WPDITFC PTAP+Y    S+ Y +W ++  ++R +V+ L  ET+ F+I+   + TD+ELEERTIAM+S++P KL  D F  H+  + + R  +  Y N    N   + F  DLKPLF+  +VQIQNNIPC TFH++KS  L+ +++ S+ F L FN  SY +FNSS+  RS+FLYI+NR+ I Q   + L PGFNNI+SLSQNR  Y G++RKCR+KT+K E+YDAL Q+   FEG Y DC ++ SQ+L V  CKCY+PFLPI+KN+TG PR+CLNATF+S+ ++L+NAKCMVN    FK    +R+ +N +C  ++L KC+ + Y+++  K +  EL S     +R   IK   S +F + +++ DF E +RDN + + I+R+F   DL+KEE EYPFS+LLSDIGGLMGLWLGMSVVGLFEI E  Y++  N  LNKK
Sbjct:    1 MIEILQSSTIHGVSHIHGAKSRITKMLWIILFILGLIGIFVNIVFVIMRYFSNPVLISRNLDHEPFIWPDITFCKPTAPYYFVENSQPYNHWTEVFRRTRRIVERLSNETEFFKIMNGKRNTDYELEERTIAMSSADPYKLKMDNFSYHIMLIVFNRIRT--YTNYISDNEFFENFHEDLKPLFTAPLVQIQNNIPCFTFHINKSKSLHQDNITSIRFHLNFNIKSYMLFNSSFLHRSVFLYITNRNGIPQKYEMLLEPGFNNIVSLSQNRFEYRGVQRKCRNKTYKVELYDALLQSTSIFEGYYADCMKVESQKLCVSNCKCYNPFLPIYKNETGSPRICLNATFYSEEEILKNAKCMVNRLRKFKSFFLYRRFFNPKCQDYQLIKCNEVKYKIEKEKLLFAELSSGFTTQRRRKVIKGF-SKWFQRIDNRSDF-ERIRDNYIVITIKREFPKGDLYKEEYEYPFSQLLSDIGGLMGLWLGMSVVGLFEIFEIIYMYFTN--LNKK 501
The following BLAST results are available for this feature:
BLAST of Degenerin unc-8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
S5W2R20.000e+053.23Asic OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
A0A5J4NUF14.549e-8734.73Uncharacterized protein OS=Paragonimus westermani ... [more]
A0A183A5V16.775e-8431.81Uncharacterized protein OS=Echinostoma caproni OX=... [more]
A0A4S2L9133.913e-8033.40Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A4E0RSD96.913e-7731.34Degenerin unc-8 OS=Fasciola hepatica OX=6192 GN=D9... [more]
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BLAST of Degenerin unc-8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
asic1a1.805e-629.63acid-sensing (proton-gated) ion channel 1a [Source... [more]
ASIC52.720e-640.00acid sensing ion channel subunit family member 5 [... [more]
ASIC52.753e-640.00acid sensing ion channel subunit family member 5 [... [more]
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BLAST of Degenerin unc-8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Degenerin unc-8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000069054.10.000e+0100.00SMESG000069054.1[more]
SMESG000020604.10.000e+054.82SMESG000020604.1[more]
SMESG000011523.10.000e+053.61SMESG000011523.1[more]
SMESG000017678.10.000e+053.08SMESG000017678.1[more]
SMESG000069546.15.817e-17751.68SMESG000069546.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30014274 ID=SMED30014274|Name=Degenerin unc-8|organism=Schmidtea mediterranea sexual|type=transcript|length=1559bp
ATATAAGATGATCGAACTCGTTAAAAGCAGTACAATTCATGGGATAAATC
ACATTTACAGTGCCAACGGGAAACTTGCCAAATTTCTTTGGTGTGTTTTA
TTTATTTTCGGAATAATTGGGATAATTGTCAACATTTGTTTTGTTTCAAT
CAGATATTTCTCATATCCGGTACTGATTAGTTACACTTTTGAGCATGAAC
CATTCGTATGGCCTGATATTACATTCTGCAATCCTACGGCACCATTTTAT
TTGGACCGAAAATCAAAAGCGTACAAATATTGGATGCAGATCAACAATCA
GTCAAGAGATGTAGTAAAAATGTTGGTTAAGGAAACCAAATTATTTCAAA
TCATTCGTGAGTCAAAAGAAACTGACTTTGAATTGGAAGAAAGAACGATA
GCAATGGCCAGTTCCAATCCGGTCAAATTAGGAGCTGATCTATTTGAAAA
TCACGTCAAATTCGTTGGCTATACTCGTCCGCATTCGGGCATATATTTTA
ATAAAGATATTCAAAACAACAATCCAAAAACATTTCCCGGAGATCTGAAA
CCATTATTTTCGACACAGATTGTTCAAATACAAAACAATATTCCATGCCA
TACGTTTCATATGCACAAATCTAATATTCTGAACCCAAACTCAGTTCAGT
CTCTAGTATTCGGTCTAAGGTTCAATTATGACAGCTATGAGATCTTTAAT
TCGAGTTATACAACAAGATCTATCTTTCTCTACATTTCTAACAGAGACGA
GATTCAACAAGACCAAAATATATTTTTATCACCGGGTTTTAATAACATTT
TATCCTTGTCCCAGAATCGACATCATTATAACGGGTTGAGAAGAAAATGC
CGTCACAAGACCTTCAAATTTGAGGTCTATGACGCTCTATTTCAAAACGT
AAAAACATTCGAAGGTAGTTATGAAGACTGCAAACAGATAGTCAGTCAAA
GGTTGTTTGTCGATAAATGCAAATGCTATAGTCCGTTTTTACCAATATTC
AAGAATCAAACTGGTTTCCCGAGACTTTGTTTAAATGCAACATTTTTTTC
TAAAACTAAACTATTGGAAAACGCCAAATGCATGGTGAATGTATATGAAA
ACTTTAAAAAATCCGGAAATTTCCGAAAACATTACAATAACCAATGTTTG
ATTTTTAAGCTACATAAATGCGACCTGTTATCATACCAAATGGACCTAAG
GAAGGATATGTTGGTTGAGTTGTGGTCTAAAGTTTACAATGGAAAACGGC
TCAACTCAATTAAATTCATGCATAGTTATTATTTCGGTAAAAATGAATCC
AAAAAAGATTTTAATGAAGTAATGAGGGATAATATTGTTGATTTAATCAT
TGAGAGAAAGTTTGAATATAGTGACTTGTTCAAGGAGGAGAGGGAATATC
CCTTTTCGGAGTTGTTATCAGATATTGGGGGATTAATGGGACTTTGGTTG
GGAATGAGTGTCGTAGGATTATTTGAAATTCTCGAATTCTTTTATCTATT
CTCCATCAATGCTTGTTTAAACAAAAAAAACAAATCTCGATTTTCACCTA
AAAATATTC
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protein sequence of SMED30014274-orf-1

>SMED30014274-orf-1 ID=SMED30014274-orf-1|Name=SMED30014274-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=519bp
YKMIELVKSSTIHGINHIYSANGKLAKFLWCVLFIFGIIGIIVNICFVSI
RYFSYPVLISYTFEHEPFVWPDITFCNPTAPFYLDRKSKAYKYWMQINNQ
SRDVVKMLVKETKLFQIIRESKETDFELEERTIAMASSNPVKLGADLFEN
HVKFVGYTRPHSGIYFNKDIQNNNPKTFPGDLKPLFSTQIVQIQNNIPCH
TFHMHKSNILNPNSVQSLVFGLRFNYDSYEIFNSSYTTRSIFLYISNRDE
IQQDQNIFLSPGFNNILSLSQNRHHYNGLRRKCRHKTFKFEVYDALFQNV
KTFEGSYEDCKQIVSQRLFVDKCKCYSPFLPIFKNQTGFPRLCLNATFFS
KTKLLENAKCMVNVYENFKKSGNFRKHYNNQCLIFKLHKCDLLSYQMDLR
KDMLVELWSKVYNGKRLNSIKFMHSYYFGKNESKKDFNEVMRDNIVDLII
ERKFEYSDLFKEEREYPFSELLSDIGGLMGLWLGMSVVGLFEILEFFYLF
SINACLNKKNKSRFSPKNI
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Aliases
The feature 'Degenerin unc-8' has the following synonyms
Synonym
asic
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0005272sodium channel activity
Vocabulary: biological process
TermDefinition
GO:0006814sodium ion transport
GO:0006810transport
GO:0006811ion transport
GO:0035725sodium ion transmembrane transport
Vocabulary: INTERPRO
TermDefinition
IPR001873ENaC
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001873Epithelial sodium channelPRINTSPR01078AMINACHANNELcoord: 476..492
score: 49.88
coord: 462..476
score: 36.53
coord: 66..82
score: 26.12
coord: 316..333
score: 31.78
IPR001873Epithelial sodium channelPFAMPF00858ASCcoord: 8..496
e-value: 8.7E-45
score: 153.5
IPR001873Epithelial sodium channelPANTHERPTHR11690AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATEDcoord: 9..510
NoneNo IPR availableGENE3DG3DSA:2.60.470.10coord: 57..464
e-value: 2.7E-27
score: 97.7
NoneNo IPR availableGENE3DG3DSA:1.10.287.820coord: 276..390
e-value: 2.7E-27
score: 97.7
NoneNo IPR availableGENE3DG3DSA:1.10.287.770coord: 27..494
e-value: 2.7E-27
score: 97.7
NoneNo IPR availableGENE3DG3DSA:1.10.3590.10coord: 79..240
e-value: 2.7E-27
score: 97.7
NoneNo IPR availableTMHMMTMhelixcoord: 478..500
NoneNo IPR availableTMHMMTMhelixcoord: 28..50