Oxysterol-binding protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30014257 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 435.261 bits (1118), Expect = 1.070e-143 Identity = 211/429 (49.18%), Postives = 284/429 (66.20%), Query Frame = 3
Query: 1269 NTSNIATFSEVIPIRSKRT-RRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETV-----KGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDG--------TKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ N+ + ++P S + RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR DD G R EQ+ HHPPS A + S W W + ++S+KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T D+C L + PYS FS + ++VTG ++D VL+G+WDE++E V+ ++ + K +T T S+ LLW++YPLP N + YYFS A+TLNE EE +APTDSR RPDQ+LME+G+WDEAN EK RLEE+QR R L+ G ++ Y PLWF+ DP + G YWE K K+DW MC IF
Sbjct: 33 SADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQT-LSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF 460
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 436.417 bits (1121), Expect = 7.204e-143 Identity = 211/429 (49.18%), Postives = 284/429 (66.20%), Query Frame = 3
Query: 1269 NTSNIATFSEVIPIRSKRT-RRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETV-----KGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDG--------TKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ N+ + ++P S + RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR DD G R EQ+ HHPPS A + S W W + ++S+KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T D+C L + PYS FS + ++VTG ++D VL+G+WDE++E V+ ++ + K +T T S+ LLW++YPLP N + YYFS A+TLNE EE +APTDSR RPDQ+LME+G+WDEAN EK RLEE+QR R L+ G ++ Y PLWF+ DP + G YWE K K+DW MC IF
Sbjct: 122 SADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQT-LSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF 549
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 438.728 bits (1127), Expect = 1.372e-142 Identity = 211/426 (49.53%), Postives = 283/426 (66.43%), Query Frame = 3
Query: 1278 NIATFSEVIPIRSKRT-RRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETV-----KGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDG--------TKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
N+ + ++P S + RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR DD G R EQ+ HHPPS A + S W W + ++S+KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T D+C L + PYS FS + ++VTG ++D VL+G+WDE++E V+ ++ + K +T T S+ LLW++YPLP N + YYFS A+TLNE EE +APTDSR RPDQ+LME+G+WDEAN EK RLEE+QR R L+ G ++ Y PLWF+ DP + G YWE K K+DW MC IF
Sbjct: 212 NVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQT-LSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF 636 HSP 2 Score: 71.2478 bits (173), Expect = 5.560e-12 Identity = 43/134 (32.09%), Postives = 75/134 (55.97%), Query Frame = 3
Query: 411 DNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSS 812
D + D +EL + + L+ L+D+ D++ + LQ+S+ +LD K + GE KLK + ERAT+FR+++ +++ +C + E + KW++ + E+EQR +E +E LAKQH LE S+
Sbjct: 12 DEATTPADKSEL-HHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGE---KLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA 141
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 437.187 bits (1123), Expect = 1.375e-142 Identity = 211/429 (49.18%), Postives = 284/429 (66.20%), Query Frame = 3
Query: 1269 NTSNIATFSEVIPIRSKRT-RRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETV-----KGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDG--------TKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ N+ + ++P S + RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR DD G R EQ+ HHPPS A + S W W + ++S+KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T D+C L + PYS FS + ++VTG ++D VL+G+WDE++E V+ ++ + K +T T S+ LLW++YPLP N + YYFS A+TLNE EE +APTDSR RPDQ+LME+G+WDEAN EK RLEE+QR R L+ G ++ Y PLWF+ DP + G YWE K K+DW MC IF
Sbjct: 161 SADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQT-LSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF 588
BLAST of Oxysterol-binding protein vs. Ensembl Human
Match: OSBP2 (oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]) HSP 1 Score: 438.343 bits (1126), Expect = 3.791e-142 Identity = 212/427 (49.65%), Postives = 283/427 (66.28%), Query Frame = 3
Query: 1278 NIATFSEVIPI-RSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETV-----KGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDG---------TKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
N+ + ++P SK RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR DD G R EQ+ HHPPS A + S W W + ++S+KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T D+C L + PYS FS + ++VTG ++D VL+G+WDE++E V+ ++ + K +T T S+ LLW++YPLP N + YYFS A+TLNE EE +APTDSR RPDQ+LME+G+WDEAN EK RLEE+QR R L+ G ++ Y PLWF+ DP + G YWE K K+DW MC IF
Sbjct: 234 NVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQT-LSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEAEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF 659 HSP 2 Score: 71.2478 bits (173), Expect = 6.291e-12 Identity = 43/134 (32.09%), Postives = 75/134 (55.97%), Query Frame = 3
Query: 411 DNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSS 812
D + D +EL + + L+ L+D+ D++ + LQ+S+ +LD K + GE KLK + ERAT+FR+++ +++ +C + E + KW++ + E+EQR +E +E LAKQH LE S+
Sbjct: 33 DEATTPADKSEL-HHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGE---KLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA 162
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 382.874 bits (982), Expect = 5.411e-124 Identity = 198/410 (48.29%), Postives = 271/410 (66.10%), Query Frame = 3
Query: 1311 RSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS---NTETVKGRTYLATEESSI-LLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ R RRT +P +PN+ +NLWS++KNCIGK+LSKIPMPVNFSEPIS+LQR+ ED EY+++L+ A +EQ+ YVAA+ S+Y+ T +R NKPFNPLLGET+E DR DD GWR EQ+ HHPP+ A H E N W + DF+M+++FRGKY+ + PIG H++F +K H+ + +I T+HNIIVG++WIDNHG+M+I N T +KC L + PYS FS + P++V G + D V+ GTWD+ ++ V S N E K L +E+S+ +W PLP N +K + F+ AI LNE EE +APTDSR RPDQ+LME G+WDEAN++K +EE+QR R E+ G K EY+P WF V D + ++F G YWE K +++W C IF
Sbjct: 47 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLST-LEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPK----LEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGDK--YEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 449
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 388.652 bits (997), Expect = 6.737e-124 Identity = 198/410 (48.29%), Postives = 271/410 (66.10%), Query Frame = 3
Query: 1311 RSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS---NTETVKGRTYLATEESSI-LLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ R RRT +P +PN+ +NLWS++KNCIGK+LSKIPMPVNFSEPIS+LQR+ ED EY+++L+ A +EQ+ YVAA+ S+Y+ T +R NKPFNPLLGET+E DR DD GWR EQ+ HHPP+ A H E N W + DF+M+++FRGKY+ + PIG H++F +K H+ + +I T+HNIIVG++WIDNHG+M+I N T +KC L + PYS FS + P++V G + D V+ GTWD+ ++ V S N E K L +E+S+ +W PLP N +K + F+ AI LNE EE +APTDSR RPDQ+LME G+WDEAN++K +EE+QR R E+ G K EY+P WF V D + ++F G YWE K +++W C IF
Sbjct: 225 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLST-LEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPK----LEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGDK--YEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 627 HSP 2 Score: 55.0694 bits (131), Expect = 2.156e-7 Identity = 39/169 (23.08%), Postives = 89/169 (52.66%), Query Frame = 3
Query: 411 DNNDSELDSNELVNGFIL---KLNGHLEDIKKSQDVLYRKLDDLQKSIHD-LDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFE 905
D ++ DSN + IL +++G L D++ + +++ ++ D+L ++++ ++ DKNS + ERA + +++ +++L + + E A++ K++ E++++ ++ +E LAKQH LE S + +++ +QE D++F+DA E
Sbjct: 28 DAQMAKTDSNR-SDALILANRQMSGKLCDLRTAANMMNKQGDELMRALNGTVETDKNS------------LAERADLLKMTTSAVLQAAEEFVELSEQSAKRLNKIVAVEQKEKALLQEQLEALAKQHSSLERAASKCARGAAPVSVYSDQE--------DDEFHDAEE 175
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 389.423 bits (999), Expect = 7.389e-123 Identity = 198/410 (48.29%), Postives = 271/410 (66.10%), Query Frame = 3
Query: 1311 RSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS---NTETVKGRTYLATEESSI-LLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ R RRT +P +PN+ +NLWS++KNCIGK+LSKIPMPVNFSEPIS+LQR+ ED EY+++L+ A +EQ+ YVAA+ S+Y+ T +R NKPFNPLLGET+E DR DD GWR EQ+ HHPP+ A H E N W + DF+M+++FRGKY+ + PIG H++F +K H+ + +I T+HNIIVG++WIDNHG+M+I N T +KC L + PYS FS + P++V G + D V+ GTWD+ ++ V S N E K L +E+S+ +W PLP N +K + F+ AI LNE EE +APTDSR RPDQ+LME G+WDEAN++K +EE+QR R E+ G K EY+P WF V D + ++F G YWE K +++W C IF
Sbjct: 330 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLST-LEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPK----LEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGDK--YEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 732 HSP 2 Score: 140.198 bits (352), Expect = 5.588e-34 Identity = 85/271 (31.37%), Postives = 158/271 (58.30%), Query Frame = 3
Query: 117 GYLYKWTNYLKGYQKRWFVL-QNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSEL---DSNELVNGFIL---KLNGHLEDIKKSQDVLYRKLDDLQKSIHD-LDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFE 905
G+L KWTNYLKGY++RWFVL N LSYYRN SE+ CRG+IN+ A+++ +TS ++ QTFH+K QNE + ++WT++L + KA + ++ D+++ DSN + IL +++G L D++ + +++ ++ D+L ++++ ++ DKNS + ERA + +++ +++L + + E A++ K++ E++++ ++ +E LAKQH LE S + +++ +QE D++F+DA E
Sbjct: 31 GWLNKWTNYLKGYRQRWFVLDSNATLSYYRNPSEVGHTCRGSINLQEARVHTDKTTSCIVISGQSQTFHVKPQNEMDRQQWTNSLEYMRHKAITRAESEEDEDAQMAKTDSNR-SDALILANRQMSGKLCDLRTAANMMNKQGDELMRALNGTVETDKNS------------LAERADLLKMTTSAVLQAAEEFVELSEQSAKRLNKIVAVEQKEKALLQEQLEALAKQHSSLERAASKCARGAAPVSVYSDQE--------DDEFHDAEE 280
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 389.037 bits (998), Expect = 1.895e-122 Identity = 198/410 (48.29%), Postives = 271/410 (66.10%), Query Frame = 3
Query: 1311 RSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS---NTETVKGRTYLATEESSI-LLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ R RRT +P +PN+ +NLWS++KNCIGK+LSKIPMPVNFSEPIS+LQR+ ED EY+++L+ A +EQ+ YVAA+ S+Y+ T +R NKPFNPLLGET+E DR DD GWR EQ+ HHPP+ A H E N W + DF+M+++FRGKY+ + PIG H++F +K H+ + +I T+HNIIVG++WIDNHG+M+I N T +KC L + PYS FS + P++V G + D V+ GTWD+ ++ V S N E K L +E+S+ +W PLP N +K + F+ AI LNE EE +APTDSR RPDQ+LME G+WDEAN++K +EE+QR R E+ G K EY+P WF V D + ++F G YWE K +++W C IF
Sbjct: 364 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLST-LEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPK----LEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGDK--YEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 766 HSP 2 Score: 140.584 bits (353), Expect = 4.852e-34 Identity = 85/271 (31.37%), Postives = 158/271 (58.30%), Query Frame = 3
Query: 117 GYLYKWTNYLKGYQKRWFVL-QNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSEL---DSNELVNGFIL---KLNGHLEDIKKSQDVLYRKLDDLQKSIHD-LDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFE 905
G+L KWTNYLKGY++RWFVL N LSYYRN SE+ CRG+IN+ A+++ +TS ++ QTFH+K QNE + ++WT++L + KA + ++ D+++ DSN + IL +++G L D++ + +++ ++ D+L ++++ ++ DKNS + ERA + +++ +++L + + E A++ K++ E++++ ++ +E LAKQH LE S + +++ +QE D++F+DA E
Sbjct: 65 GWLNKWTNYLKGYRQRWFVLDSNATLSYYRNPSEVGHTCRGSINLQEARVHTDKTTSCIVISGQSQTFHVKPQNEMDRQQWTNSLEYMRHKAITRAESEEDEDAQMAKTDSNR-SDALILANRQMSGKLCDLRTAANMMNKQGDELMRALNGTVETDKNS------------LAERADLLKMTTSAVLQAAEEFVELSEQSAKRLNKIVAVEQKEKALLQEQLEALAKQHSSLERAASKCARGAAPVSVYSDQE--------DDEFHDAEE 314
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Match: obr-1 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7DTF2]) HSP 1 Score: 389.423 bits (999), Expect = 1.049e-121 Identity = 198/410 (48.29%), Postives = 271/410 (66.10%), Query Frame = 3
Query: 1311 RSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS---NTETVKGRTYLATEESSI-LLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ R RRT +P +PN+ +NLWS++KNCIGK+LSKIPMPVNFSEPIS+LQR+ ED EY+++L+ A +EQ+ YVAA+ S+Y+ T +R NKPFNPLLGET+E DR DD GWR EQ+ HHPP+ A H E N W + DF+M+++FRGKY+ + PIG H++F +K H+ + +I T+HNIIVG++WIDNHG+M+I N T +KC L + PYS FS + P++V G + D V+ GTWD+ ++ V S N E K L +E+S+ +W PLP N +K + F+ AI LNE EE +APTDSR RPDQ+LME G+WDEAN++K +EE+QR R E+ G K EY+P WF V D + ++F G YWE K +++W C IF
Sbjct: 440 KGGRQRRTTVPERPNLPINLWSIMKNCIGKELSKIPMPVNFSEPISVLQRVTEDLEYANLLETGAKLST-LEQMCYVAAYAASNYSTTCHRTNKPFNPLLGETFEFDRMDDLGWRSVTEQVSHHPPAAAHHAEGNGWTMYQDFTMTSRFRGKYLSVIPIGFTHVVFPATKSHFSYRKITTTVHNIIVGKLWIDNHGDMEITNHETNEKCLLKFVPYSYFSREQPRKVYGIVRDAEGIPKYVVQGTWDKSIDMLKVSSWNGNHEKPK----LEVDETSLKRIWTANPLPKNAEKMHNFTKLAIELNEPEEGVAPTDSRLRPDQRLMENGEWDEANRKKLEIEEKQRVVRRRREAEKELAMKKGDK--YEEYEPTWFVRVQDESNGALIHQFKGGYWEAKEQQNWEKCPDIF 842 HSP 2 Score: 95.9005 bits (237), Expect = 6.069e-20 Identity = 73/285 (25.61%), Postives = 148/285 (51.93%), Query Frame = 3
Query: 150 GYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSEL---DSNELVNGFIL---KLNGHLEDIKKSQDVLYRKLDDLQKSIHD-LDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLP-----SPEINLGVSL 968
G ++ F LQ RN SE+ CRG+IN+ A+++ +TS ++ QTFH+K QNE + ++WT++L + KA + ++ D+++ DSN + IL +++G L D++ + +++ ++ D+L ++++ ++ DKNS + ERA + +++ +++L + + E A++ K++ E++++ ++ +E LAKQH LE S + +++ +QE D++F+DA E ++ +P P GV L
Sbjct: 159 GDSEKLFGLQE------RNPSEVGHTCRGSINLQEARVHTDKTTSCIVISGQSQTFHVKPQNEMDRQQWTNSLEYMRHKAITRAESEEDEDAQMAKTDSNR-SDALILANRQMSGKLCDLRTAANMMNKQGDELMRALNGTVETDKNS------------LAERADLLKMTTSAVLQAAEEFVELSEQSAKRLNKIVAVEQKEKALLQEQLEALAKQHSSLERAASKCARGAAPVSVYSDQE--------DDEFHDAEE------DLAMPCSNSNGPPATAGVHL 410
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: Osbp (gene:FBgn0020626 transcript:FBtr0084801) HSP 1 Score: 573.163 bits (1476), Expect = 0.000e+0 Identity = 313/809 (38.69%), Postives = 471/809 (58.22%), Query Frame = 3
Query: 111 IKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXX---XXGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPSPEINLGVSLPSRCXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFFIGDSSTRGFEEVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTED--KCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYE----YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+KG+L KWTNY+KGYQ+RWFVL G+LSYYRNQSE+ CRGTI++ A I+ VDS +FVIS+ G QTFH+K+ E E + W +AL A+ KA + + + + ++ ++ + L LE ++ D++ + LQ++++DL+ ++ ++ + K + ERAT+FR+++ +++ + Y + + KW K++ EREQRQR+E ++E +AKQ +E Q + V+ ++ + SDE+ + F+++E ++ + SPE S C + + + S + + G SS E KR++Q +++ ++SA + + + +L S + + + RR ++P KPN ++LW ++KNCIGKDLSKIPMP+NF+EP+SMLQRL ED+EY+ ILD AA+CQ+ EQ++Y+AAFTVS+YA T R KPFNPLLGETYE DR DD+GWR AEQ+ HHPP A+HCES W CW +FSM++KFRGKY+QI+P+G ++ F S Y W ++ T++NIIVG++W+D HGEM+I + KC L++ PYS FS D + V G + +K N V V+ GTWD K+E V+ + +V TY E L W+R P PP+ DK+Y F++ A LNE EE +APTDSR RPDQ+LME+G WDE+NKEK RLEE+QR+ R Y+P+WF + ++ + F YWE KA +++ C I+
Sbjct: 17 MKGWLLKWTNYIKGYQRRWFVLSKGVLSYYRNQSEINHTCRGTISLHGALIHTVDSCTFVISNGGTQTFHIKAGTEVERQSWVTALELAKAKAIRAIECEEEEETETAHVVPSQEISSVVRDLTDRLESMRTCYDLITKHGAALQRALNDLETNEEESL----GSRTKIVNERATLFRITSNAMINAGNDYLHTAEAQGHKWSKMLHHEREQRQRLEEIIEQMAKQQSQME-QAAVLVRQNKPVSSTSGAGTAGSLVTSDEEM-EFFDAEEHGYSGSGRSPE-------SSDCERGTFILKMHKRR------------SSSEDQVEGHLEGSSS----ESDEQKRTVQTVQQVCLVSAPR----------VASGGQGDDDDDVDKALPAKESTDSIYGRNWNPDLIKKRRDRVPDKPNHPISLWGIMKNCIGKDLSKIPMPINFNEPLSMLQRLVEDYEYTEILDYAATCQDECEQLAYIAAFTVSAYATTTNRTGKPFNPLLGETYECDRMDDYGWRCLAEQVSHHPPVAALHCESKNWTCWQEFSMTSKFRGKYVQINPLGGVYVQFPNSGRRYSWRKVTTTVNNIIVGKLWVDQHGEMEIRGSQAAEGHKCILNFIPYSYFSRDVQRSVKGVVMNKDNEVKWVVRGTWDMKIEIAPVLKTSGSVSSPTYTTGEFK--LAWRRRPAPPDSDKFYNFTTLACQLNEEEEGVAPTDSRLRPDQRLMEQGDWDESNKEKLRLEEKQRTERRRRENEAEEAAAEGRPYPAYEPMWFKREKEEGSEEYVHVFKNTYWEAKAAQNFEGCPDIY 784
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG3860 (gene:FBgn0034951 transcript:FBtr0072201) HSP 1 Score: 225.713 bits (574), Expect = 6.498e-65 Identity = 148/453 (32.67%), Postives = 223/453 (49.23%), Query Frame = 3
Query: 1314 SKRTRRTQIPPK--PNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWID--------NHGEMDIINLT---------------------TEDKCHLSYKPYSMF--------------------------SNDTPKRVTGAITD-KLNNV--CCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEED------IAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECK 2474
++ RT++P +++W+++KNCIGKDLSKI MPV +EP+S LQRL E EY+ +L +AA ++P +++ YVAAF VS+ A+ R+ KPFNPLLGETYEL + D +R+ EQ+ HHPP A H ES ++ S KF GK ++++P G + F + Y W + +HNIIVGR+WI+ NH + +LT +E + Y ++ F N TPK++ + KLN+ + + +E + I +++ Y S LW P P N +YY F+ FA+ LN ++ + + PTDSR RPD +EEG D A+KEK RLEE+QR R + + ++ P WF T+P K + ++G YW+ K
Sbjct: 7 AEHVERTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGD---YRIVCEQVSHHPPVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNLHRVEGFVKDASETNLYFLYGKWTEFIKCCSAESYVQFLKQGTRKNDDYDGSPNGTPKKMFSKLNSFKLNSFRSLSIQDSDSYPPMEQEGDIPKSDSA----YSLDIPDSTTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSD-----DWSPRWFKYATNPHTKIDDWLYSGGYWDRK 447
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: CG3860 (gene:FBgn0034951 transcript:FBtr0343288) HSP 1 Score: 192.586 bits (488), Expect = 5.457e-53 Identity = 103/267 (38.58%), Postives = 155/267 (58.05%), Query Frame = 3
Query: 1314 SKRTRRTQIPPK--PNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRT 2108
++ RT++P +++W+++KNCIGKDLSKI MPV +EP+S LQRL E EY+ +L +AA ++P +++ YVAAF VS+ A+ R+ KPFNPLLGETYEL + D +R+ EQ+ HHPP A H ES ++ S KF GK ++++P G + F + Y W + +HNIIVGR+WI+ +G+M+I N T L++K + + RV G + D L G W E ++ + S + +K T
Sbjct: 7 AEHVERTELPATMISRKEVSIWAILKNCIGKDLSKITMPVMLNEPLSFLQRLCEYMEYAQLLTEAAQQEHPADRMKYVAAFAVSALASNWERLGKPFNPLLGETYELQKGD---YRIVCEQVSHHPPVSAFHAESKDFKFHGTISPKIKFWGKSVEVNPKGTVTVEFPKWNESYSWTNVNCCVHNIIVGRLWIEQYGKMEITNHATGHVASLTFKSAGSGAKNL-HRVEGFVKDASETNLYFLYGKWTEFIKCCSAESYVQFLKQGT 269 HSP 2 Score: 80.8777 bits (198), Expect = 1.714e-15 Identity = 46/121 (38.02%), Postives = 65/121 (53.72%), Query Frame = 3
Query: 2130 SILLWQRYPLPPNFDKYYYFSSFAITLNEIEED------IAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECK 2474
S LW P P N +YY F+ FA+ LN ++ + + PTDSR RPD +EEG D A+KEK RLEE+QR R + + ++ P WF T+P K + ++G YW+ K
Sbjct: 334 STTLWSCKPRPSNCSEYYQFTHFALQLNAMDSNMKPPLTLCPTDSRLRPDILHLEEGNLDGASKEKTRLEEKQRHTRKQRKSTNSD-----DWSPRWFKYATNPHTKIDDWLYSGGYWDRK 449
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: cert (gene:FBgn0027569 transcript:FBtr0345035) HSP 1 Score: 84.7297 bits (208), Expect = 1.715e-16 Identity = 68/287 (23.69%), Postives = 136/287 (47.39%), Query Frame = 3
Query: 102 SSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINL--VDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGC---DNNDSELDSN--ELVNGFILK-----LNGHLEDIKKSQDVLYRKLDDLQK---SIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENM---VEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFES 908
S ++GYL KWTNY+ G+Q R+ VL++G LSYY+++SE CRG I++ A I D F + + + + L+++ + W L + + + L SN L +G LK L + +++ +D+L+ +++ LQ+ + +++K+ + LK + K + FR + + +LT+ E + E W++ ++ E ++R+R E+ ++D ++ + L Y P+ E + +++F+DA E+
Sbjct: 39 SIELRGYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVVNNLNNWCLRAETSEDRMHWVDVLQLYKADSGSTDTTSLRRHGSTMSLQSNTISLTSGGSLKKTQRNLREKVGELETFKDILFGQIETLQRYFDACSEVNKNNAQPLDLGDGLKSIDFKGESITFRATTSGVLTTLQHCLEIIAESDESWKRKLEREIDKRRRSEDQSKKLKDEVEKMKRLSYP-------------GPDFEEGPHSTLPEDEFFDAVET 312
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Match: cert (gene:FBgn0027569 transcript:FBtr0076717) HSP 1 Score: 84.7297 bits (208), Expect = 1.715e-16 Identity = 68/287 (23.69%), Postives = 136/287 (47.39%), Query Frame = 3
Query: 102 SSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINL--VDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGC---DNNDSELDSN--ELVNGFILK-----LNGHLEDIKKSQDVLYRKLDDLQK---SIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENM---VEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFES 908
S ++GYL KWTNY+ G+Q R+ VL++G LSYY+++SE CRG I++ A I D F + + + + L+++ + W L + + + L SN L +G LK L + +++ +D+L+ +++ LQ+ + +++K+ + LK + K + FR + + +LT+ E + E W++ ++ E ++R+R E+ ++D ++ + L Y P+ E + +++F+DA E+
Sbjct: 39 SIELRGYLSKWTNYIYGWQPRYIVLKDGTLSYYKSESESDFGCRGAISLTKATIKAHESDELRFDVVVNNLNNWCLRAETSEDRMHWVDVLQLYKADSGSTDTTSLRRHGSTMSLQSNTISLTSGGSLKKTQRNLREKVGELETFKDILFGQIETLQRYFDACSEVNKNNAQPLDLGDGLKSIDFKGESITFRATTSGVLTTLQHCLEIIAESDESWKRKLEREIDKRRRSEDQSKKLKDEVEKMKRLSYP-------------GPDFEEGPHSTLPEDEFFDAVET 312
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: CR932437.1 (oxysterol binding protein 2 [Source:NCBI gene;Acc:794414]) HSP 1 Score: 448.743 bits (1153), Expect = 1.768e-149 Identity = 211/398 (53.02%), Postives = 277/398 (69.60%), Query Frame = 3
Query: 1338 IPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKG-----RTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EYS +LD+AA C + +EQ+ VAAF+VSSY+ T +RI KPFNPLLGETYELDR +++G+R EQ+ HHPP+ A H S W W + ++ +KFRGKYI I P+G HL F S HYVW ++ T+HNIIVG++WID G++ I+N ++D CHL + PYS FS D P++VTG +TD + +L+GTWD+K+E+ +I ++ G +T T LLW++YPLP N + YYFSS A+TLNE+E+ IAPTDSR RPDQ+LME G WDEAN EK RLEE+Q R+E K D E Y+P+WF TD E ++ + G YWE K ++DWS C IF
Sbjct: 39 IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYSELLDRAARCDSSLEQMCLVAAFSVSSYSTTVHRIGKPFNPLLGETYELDRLEEYGYRSICEQISHHPPAAAHHVISQRGWTLWQEITIDSKFRGKYISIMPLGNIHLKFHTSGNHYVWSKVTSTVHNIIVGKLWIDQSGDIIIVNHRSKDTCHLKFSPYSYFSRDVPRKVTGVVTDGEGSAHYILSGTWDDKMESAKIIESSHACGGSEGKQKTVYQTLPPK-LLWKKYPLPENAENMYYFSSLALTLNELEDGIAPTDSRLRPDQRLMEAGLWDEANTEKQRLEERQ---RLERRKRDAQANLEVETYQPIWFMKRTDLETGESSFMYKGGYWEAKDRQDWSQCPAIF 432
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: CR932437.1 (oxysterol binding protein 2 [Source:NCBI gene;Acc:794414]) HSP 1 Score: 451.44 bits (1160), Expect = 1.933e-149 Identity = 211/398 (53.02%), Postives = 277/398 (69.60%), Query Frame = 3
Query: 1338 IPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKG-----RTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EYS +LD+AA C + +EQ+ VAAF+VSSY+ T +RI KPFNPLLGETYELDR +++G+R EQ+ HHPP+ A H S W W + ++ +KFRGKYI I P+G HL F S HYVW ++ T+HNIIVG++WID G++ I+N ++D CHL + PYS FS D P++VTG +TD + +L+GTWD+K+E+ +I ++ G +T T LLW++YPLP N + YYFSS A+TLNE+E+ IAPTDSR RPDQ+LME G WDEAN EK RLEE+Q R+E K D E Y+P+WF TD E ++ + G YWE K ++DWS C IF
Sbjct: 120 IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYSELLDRAARCDSSLEQMCLVAAFSVSSYSTTVHRIGKPFNPLLGETYELDRLEEYGYRSICEQISHHPPAAAHHVISQRGWTLWQEITIDSKFRGKYISIMPLGNIHLKFHTSGNHYVWSKVTSTVHNIIVGKLWIDQSGDIIIVNHRSKDTCHLKFSPYSYFSRDVPRKVTGVVTDGEGSAHYILSGTWDDKMESAKIIESSHACGGSEGKQKTVYQTLPPK-LLWKKYPLPENAENMYYFSSLALTLNELEDGIAPTDSRLRPDQRLMEAGLWDEANTEKQRLEERQ---RLERRKRDAQANLEVETYQPIWFMKRTDLETGESSFMYKGGYWEAKDRQDWSQCPAIF 513 HSP 2 Score: 52.7582 bits (125), Expect = 1.725e-6 Identity = 28/93 (30.11%), Postives = 45/93 (48.39%), Query Frame = 3
Query: 660 SCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE--YQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVT 932
+C + + G + +W++ + EREQR +E +E LAKQH LE ++ S S NQ + +ED+ +F+DA E V
Sbjct: 2 ACQDFVDLAEGHSRRWQRALQYEREQRHHLEETIEQLAKQHNSLERAWRESPSTHNQAAEGTLEGESSEENEDI---EFFDAMEDSPAFITVV 91
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: CR932437.1 (oxysterol binding protein 2 [Source:NCBI gene;Acc:794414]) HSP 1 Score: 448.743 bits (1153), Expect = 5.703e-149 Identity = 211/398 (53.02%), Postives = 277/398 (69.60%), Query Frame = 3
Query: 1338 IPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKG-----RTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EYS +LD+AA C + +EQ+ VAAF+VSSY+ T +RI KPFNPLLGETYELDR +++G+R EQ+ HHPP+ A H S W W + ++ +KFRGKYI I P+G HL F S HYVW ++ T+HNIIVG++WID G++ I+N ++D CHL + PYS FS D P++VTG +TD + +L+GTWD+K+E+ +I ++ G +T T LLW++YPLP N + YYFSS A+TLNE+E+ IAPTDSR RPDQ+LME G WDEAN EK RLEE+Q R+E K D E Y+P+WF TD E ++ + G YWE K ++DWS C IF
Sbjct: 78 IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYSELLDRAARCDSSLEQMCLVAAFSVSSYSTTVHRIGKPFNPLLGETYELDRLEEYGYRSICEQISHHPPAAAHHVISQRGWTLWQEITIDSKFRGKYISIMPLGNIHLKFHTSGNHYVWSKVTSTVHNIIVGKLWIDQSGDIIIVNHRSKDTCHLKFSPYSYFSRDVPRKVTGVVTDGEGSAHYILSGTWDDKMESAKIIESSHACGGSEGKQKTVYQTLPPK-LLWKKYPLPENAENMYYFSSLALTLNELEDGIAPTDSRLRPDQRLMEAGLWDEANTEKQRLEERQ---RLERRKRDAQANLEVETYQPIWFMKRTDLETGESSFMYKGGYWEAKDRQDWSQCPAIF 471
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: osbp2 (oxysterol binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-091113-18]) HSP 1 Score: 455.677 bits (1171), Expect = 5.573e-148 Identity = 214/402 (53.23%), Postives = 280/402 (69.65%), Query Frame = 3
Query: 1338 IPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKG-----RTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEI-----LKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EYS +LD+AA C + +EQ+ VAAF+VSSY+ T +RI KPFNPLLGETYELDR +++G+R EQ+ HHPP+ A H S W W + ++ +KFRGKYI I P+G HL F S HYVW ++ T+HNIIVG++WID G++ I+N ++D CHL + PYS FS D P++VTG +TD + +L+GTWDEK+E+ +I ++ G +T T LLW++YPLP N + YYFSS A+TLNE+E+ IAPTDSR RPDQ+LME G WDEAN EK RLEE+QR R + L L+ KE V Y+P+WF TD E ++ + G YWE K ++DWS C IF
Sbjct: 340 IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYSELLDRAARCDSSLEQMCLVAAFSVSSYSTTVHRIGKPFNPLLGETYELDRLEEYGYRSICEQISHHPPAAAHHVISQRGWTLWQEITIDSKFRGKYISIMPLGNIHLKFHTSGNHYVWSKVTSTVHNIIVGKLWIDQSGDIIIVNHRSKDTCHLKFSPYSYFSRDVPRKVTGVVTDGEGSAHYILSGTWDEKMESAKIIESSHACGGSEGKQKTVYQTLPPK-LLWKKYPLPENAENMYYFSSLALTLNELEDGIAPTDSRLRPDQRLMEAGLWDEANTEKQRLEERQRLERRKRDAQANLALEEGKE-VETYQPIWFMKRTDLETGESSFMYKGGYWEAKDRQDWSQCPAIF 739 HSP 2 Score: 182.956 bits (463), Expect = 1.168e-47 Identity = 104/278 (37.41%), Postives = 161/278 (57.91%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSE----LDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE--YQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNV 929
KG+L+KWTNYLKGYQ+RWFVL NGLLSYYR Q+EMA CRGTI + I + D+ FV++ SG +++HLK+ +E E +RW SAL A+ A ++ D++ E L+ G + L LED+ +++ + LQ+S+ +L+ D + G KLK + ERAT+FR+++ +++ +C + + G + +W++ + EREQR +E +E LAKQH LE ++ S S NQ + +ED+ +F+DA E V
Sbjct: 24 KGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTITLATVHIEVGDTCHFVLT-SGGRSYHLKAYSEGECQRWVSALQQAKANATHMMPHSDDSGDEGPLAQPDRALIQGALKTLVSKLEDLSTCNELIGKHGAALQRSLSELE-DLRAPTDG--TDKLKTVNERATLFRITSNAMINACQDFVDLAEGHSRRWQRALQYEREQRHHLEETIEQLAKQHNSLERAWRESPSTLNQAAEGTLEGESSEENEDI---EFFDAMEDSPAFITV 294
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Match: osbp2 (oxysterol binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-091113-18]) HSP 1 Score: 456.062 bits (1172), Expect = 6.168e-148 Identity = 214/402 (53.23%), Postives = 280/402 (69.65%), Query Frame = 3
Query: 1338 IPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKG-----RTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEI-----LKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EYS +LD+AA C + +EQ+ VAAF+VSSY+ T +RI KPFNPLLGETYELDR +++G+R EQ+ HHPP+ A H S W W + ++ +KFRGKYI I P+G HL F S HYVW ++ T+HNIIVG++WID G++ I+N ++D CHL + PYS FS D P++VTG +TD + +L+GTWDEK+E+ +I ++ G +T T LLW++YPLP N + YYFSS A+TLNE+E+ IAPTDSR RPDQ+LME G WDEAN EK RLEE+QR R + L L+ KE V Y+P+WF TD E ++ + G YWE K ++DWS C IF
Sbjct: 349 IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYSELLDRAARCDSSLEQMCLVAAFSVSSYSTTVHRIGKPFNPLLGETYELDRLEEYGYRSICEQISHHPPAAAHHVISQRGWTLWQEITIDSKFRGKYISIMPLGNIHLKFHTSGNHYVWSKVTSTVHNIIVGKLWIDQSGDIIIVNHRSKDTCHLKFSPYSYFSRDVPRKVTGVVTDGEGSAHYILSGTWDEKMESAKIIESSHACGGSEGKQKTVYQTLPPK-LLWKKYPLPENAENMYYFSSLALTLNELEDGIAPTDSRLRPDQRLMEAGLWDEANTEKQRLEERQRLERRKRDAQANLALEEGKE-VETYQPIWFMKRTDLETGESSFMYKGGYWEAKDRQDWSQCPAIF 748 HSP 2 Score: 182.956 bits (463), Expect = 1.216e-47 Identity = 104/278 (37.41%), Postives = 161/278 (57.91%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSE----LDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE--YQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNV 929
KG+L+KWTNYLKGYQ+RWFVL NGLLSYYR Q+EMA CRGTI + I + D+ FV++ SG +++HLK+ +E E +RW SAL A+ A ++ D++ E L+ G + L LED+ +++ + LQ+S+ +L+ D + G KLK + ERAT+FR+++ +++ +C + + G + +W++ + EREQR +E +E LAKQH LE ++ S S NQ + +ED+ +F+DA E V
Sbjct: 24 KGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTITLATVHIEVGDTCHFVLT-SGGRSYHLKAYSEGECQRWVSALQQAKANATHMMPHSDDSGDEGPLAQPDRALIQGALKTLVSKLEDLSTCNELIGKHGAALQRSLSELE-DLRAPTDG--TDKLKTVNERATLFRITSNAMINACQDFVDLAEGHSRRWQRALQYEREQRHHLEETIEQLAKQHNSLERAWRESPSTLNQAAEGTLEGESSEENEDI---EFFDAMEDSPAFITV 294
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: ccdc6 (coiled-coil domain containing 6 [Source:Xenbase;Acc:XB-GENE-978266]) HSP 1 Score: 452.21 bits (1162), Expect = 3.398e-146 Identity = 213/421 (50.59%), Postives = 286/421 (67.93%), Query Frame = 3
Query: 1296 EVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSI-------LLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQ--------RSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
E+IP K+ RRT+IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LDKA C++ IEQ+ ++AAF+VSSY+ T +R KPFNPLLGET+ELDR DD G+R EQ+ HHPP+ A + S N W W + ++++KFRGKY+ I P+G HL F S HYVW ++ T+HNIIVG++WID G+++IIN T+DKC L + PYS FS D ++VTG +TD VL+GTWDEK+E ++ ++ G + ++ ++ LLW++YPLP N + Y+FS FA+TLNE +E +APTDSRNRPDQ+LME GKWDEAN EK RLEE+Q + +++ E Y+PLWF+ DP + G YWECK ++DWS C IF
Sbjct: 347 ELIP---KKRRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAVKCESSIEQMCFIAAFSVSSYSTTVHRTAKPFNPLLGETFELDRLDDLGFRSICEQVSHHPPAAAHYVHSKNGWKLWQEITIASKFRGKYLSIMPLGDIHLEFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIINYKTKDKCQLKFSPYSYFSRDIARKVTGVVTDANGKAHYVLSGTWDEKMECAKIVQSSH---GNSCAEGKQKTVYQTLPPKLLWKKYPLPENAENMYFFSEFALTLNESDESVAPTDSRNRPDQRLMENGKWDEANVEKQRLEEKQRAVRRRREAEAVEALEEVNQRSESPNRYQPLWFERKVDPYTGELICNYKGGYWECKERQDWSCCPDIF 761 HSP 2 Score: 182.956 bits (463), Expect = 2.459e-47 Identity = 109/288 (37.85%), Postives = 168/288 (58.33%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXX------XXXXXGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQI---------SSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVT 932
KG+L+KWTNYLKGYQ+RWFVL NGLLSYYR Q+EMA CRGTIN+ A I+ DS + V+++ G +T+HLK+ E E +RW +AL A+ KA Q G + S+ D +EL + + L L+D+ D++ + LQ+S+ +L+ N + E K+K++ ERAT+FR+++ +++ +C + + + KW + + EREQR R+E +E LAKQH LE ++ V N K N+ + ++DED + +++DA E VT
Sbjct: 21 KGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLSTAHIDTEDSCNIVLTNGG-RTYHLKASCEVERQRWVTALELAKAKAIRMMNNQSDDSGDEEPSSQSDKSEL-HSSLKALTSKLDDLSTCNDLIAKHGAALQRSLSELE---NLKLPAESGEKIKSVNERATLFRITSNAMINACRDFLDLAETHSRKWHRALQYEREQRVRLEETIEQLAKQHNSLERACRGAPGLTSNTTGVLNTPKGNVPAIKGEASDED-EETEYFDAMEDAPAFITVT 302
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: ccdc6 (coiled-coil domain containing 6 [Source:Xenbase;Acc:XB-GENE-978266]) HSP 1 Score: 452.595 bits (1163), Expect = 3.893e-146 Identity = 216/417 (51.80%), Postives = 286/417 (68.59%), Query Frame = 3
Query: 1296 EVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSI-------LLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFV---YE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
E+IP K+ RRT+IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LDKA C++ IEQ+ ++AAF+VSSY+ T +R KPFNPLLGET+ELDR DD G+R EQ+ HHPP+ A + S N W W + ++++KFRGKY+ I P+G HL F S HYVW ++ T+HNIIVG++WID G+++IIN T+DKC L + PYS FS D ++VTG +TD VL+GTWDEK+E ++ ++ G + ++ ++ LLW++YPLP N + Y+FS FA+TLNE +E +APTDSRNRPDQ+LME GKWDEAN EK RLEE+QR+ R YE Y+PLWF+ DP + G YWECK ++DWS C IF
Sbjct: 367 ELIP---KKRRRTRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAVKCESSIEQMCFIAAFSVSSYSTTVHRTAKPFNPLLGETFELDRLDDLGFRSICEQVSHHPPAAAHYVHSKNGWKLWQEITIASKFRGKYLSIMPLGDIHLEFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIINYKTKDKCQLKFSPYSYFSRDIARKVTGVVTDANGKAHYVLSGTWDEKMECAKIVQSSH---GNSCAEGKQKTVYQTLPPKLLWKKYPLPENAENMYFFSEFALTLNESDESVAPTDSRNRPDQRLMENGKWDEANVEKQRLEEKQRAVRRRREAEAVEALEEGNDYEGYQPLWFERKVDPYTGELICNYKGGYWECKERQDWSCCPDIF 777 HSP 2 Score: 186.808 bits (473), Expect = 1.311e-48 Identity = 111/295 (37.63%), Postives = 170/295 (57.63%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRW-TSXXXXXXXXXXXXXXGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQI---------SSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTL-----PSPEIN 953
KG+L+KWTNYLKGYQ+RWFVL NGLLSYYR Q+EMA CRGTIN+ A I+ DS + V+++ G +T+HLK+ E E +RW T+ LA K + G + S+ D +EL + + L L+D+ D++ + LQ+S+ +L+ N + E K+K++ ERAT+FR+++ +++ +C + + + KW + + EREQR R+E +E LAKQH LE ++ V N K N+ + ++DED + +++DA E VT SPE N
Sbjct: 72 KGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLSTAHIDTEDSCNIVLTNGG-RTYHLKASCEVERQRWVTALELAKAKLLAENDSGDEEPSSQSDKSEL-HSSLKALTSKLDDLSTCNDLIAKHGAALQRSLSELE---NLKLPAESGEKIKSVNERATLFRITSNAMINACRDFLDLAETHSRKWHRALQYEREQRVRLEETIEQLAKQHNSLERACRGAPGLTSNTTGVLNTPKGNVPAIKGEASDED-EETEYFDAMEDAPAFITVTADPKQHSSPESN 360
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBP (oxysterol binding protein [Source:NCBI gene;Acc:100488223]) HSP 1 Score: 422.55 bits (1085), Expect = 1.120e-135 Identity = 209/405 (51.60%), Postives = 277/405 (68.40%), Query Frame = 3
Query: 1317 KRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
++ RRT+IP KPN ++NLWSV+KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY ++LD+ A C++ +EQ+ VAAFTVSSY+ T +R +KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H ES W + ++++KFRGKY+ I P+G H +F S HY W+++ T+HNIIVG++WID E+DI+N T D+C L + PYS FS D ++V+G + D V L GTWDE++E V S TV ++ ILLW+R PLP N + YYF+ FA+TLN EE AP+DSR+RPDQ+LME G WDEAN EK RLEE+QR+ R E DG+ V YKP+WF+ DP +K T+ G YWECK ++DW+ C IF
Sbjct: 290 RKERRTRIPYKPNYSLNLWSVMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHTLLDRGAQCESALEQLCLVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRMEESGYRSLCEQVSHHPPAAAHHAESRHGWTLRQEITVTSKFRGKYLSIMPLGTIHCVFHNSGNHYTWKKVTTTVHNIIVGKLWIDQEREIDIVNHKTGDRCKLKFAPYSYFSRDVARKVSGEVMDATGRVHYTLMGTWDERMECIPVYS-VSTVSENGGDKAADNKILLWKRNPLPKNAEYMYYFTEFALTLNAPEEGTAPSDSRHRPDQRLMENGNWDEANSEKQRLEEKQRNTRKKREAERERAGEDGSP--VDTYKPMWFERKMDPVSKEMTHICRGIYWECKERQDWASCPDIF 691 HSP 2 Score: 129.028 bits (323), Expect = 4.310e-30 Identity = 70/202 (34.65%), Postives = 125/202 (61.88%), Query Frame = 3
Query: 201 RNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDSNEL----VNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE 794
R+++EM CRGTIN+ A I++ DS +FVIS+ G QT+HLK+ +E E +RW +AL A+ +A + D++ E S++ V+ + L+G +ED+ D++ + LQ+S+ +L+ + + E + K+K + ERAT+FR+++ +++ +C + +++W++ + ER+QR R+E +E LAKQH HLE
Sbjct: 9 RSKAEMRHTCRGTINLATANISVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKARAVKMQAESDDSGDEDPSSQTDKAEVHSTLRALSGKVEDLGTCNDLIAKHGTALQRSLSELESLR---LPQESSEKIKQVNERATLFRITSNAMINACRDFMSLAESHSKRWQRALQYERDQRLRLEETLEQLAKQHNHLE 207
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBP (oxysterol binding protein [Source:NCBI gene;Acc:100488223]) HSP 1 Score: 423.705 bits (1088), Expect = 1.347e-135 Identity = 209/405 (51.60%), Postives = 277/405 (68.40%), Query Frame = 3
Query: 1317 KRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
++ RRT+IP KPN ++NLWSV+KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY ++LD+ A C++ +EQ+ VAAFTVSSY+ T +R +KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H ES W + ++++KFRGKY+ I P+G H +F S HY W+++ T+HNIIVG++WID E+DI+N T D+C L + PYS FS D ++V+G + D V L GTWDE++E V S TV ++ ILLW+R PLP N + YYF+ FA+TLN EE AP+DSR+RPDQ+LME G WDEAN EK RLEE+QR+ R E DG+ V YKP+WF+ DP +K T+ G YWECK ++DW+ C IF
Sbjct: 339 RKERRTRIPYKPNYSLNLWSVMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHTLLDRGAQCESALEQLCLVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRMEESGYRSLCEQVSHHPPAAAHHAESRHGWTLRQEITVTSKFRGKYLSIMPLGTIHCVFHNSGNHYTWKKVTTTVHNIIVGKLWIDQEREIDIVNHKTGDRCKLKFAPYSYFSRDVARKVSGEVMDATGRVHYTLMGTWDERMECIPVYS-VSTVSENGGDKAADNKILLWKRNPLPKNAEYMYYFTEFALTLNAPEEGTAPSDSRHRPDQRLMENGNWDEANSEKQRLEEKQRNTRKKREAERERAGEDGSP--VDTYKPMWFERKMDPVSKEMTHICRGIYWECKERQDWASCPDIF 740 HSP 2 Score: 126.331 bits (316), Expect = 3.498e-29 Identity = 69/201 (34.33%), Postives = 124/201 (61.69%), Query Frame = 3
Query: 204 NQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDSNEL----VNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE 794
+++EM CRGTIN+ A I++ DS +FVIS+ G QT+HLK+ +E E +RW +AL A+ +A + D++ E S++ V+ + L+G +ED+ D++ + LQ+S+ +L+ + + E + K+K + ERAT+FR+++ +++ +C + +++W++ + ER+QR R+E +E LAKQH HLE
Sbjct: 66 SKAEMRHTCRGTINLATANISVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKARAVKMQAESDDSGDEDPSSQTDKAEVHSTLRALSGKVEDLGTCNDLIAKHGTALQRSLSELESLR---LPQESSEKIKQVNERATLFRITSNAMINACRDFMSLAESHSKRWQRALQYERDQRLRLEETLEQLAKQHNHLE 263
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Match: OSBP (oxysterol binding protein [Source:NCBI gene;Acc:100488223]) HSP 1 Score: 423.32 bits (1087), Expect = 2.244e-135 Identity = 209/405 (51.60%), Postives = 277/405 (68.40%), Query Frame = 3
Query: 1317 KRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRR------VEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
++ RRT+IP KPN ++NLWSV+KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY ++LD+ A C++ +EQ+ VAAFTVSSY+ T +R +KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H ES W + ++++KFRGKY+ I P+G H +F S HY W+++ T+HNIIVG++WID E+DI+N T D+C L + PYS FS D ++V+G + D V L GTWDE++E V S TV ++ ILLW+R PLP N + YYF+ FA+TLN EE AP+DSR+RPDQ+LME G WDEAN EK RLEE+QR+ R E DG+ V YKP+WF+ DP +K T+ G YWECK ++DW+ C IF
Sbjct: 336 RKERRTRIPYKPNYSLNLWSVMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHTLLDRGAQCESALEQLCLVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRMEESGYRSLCEQVSHHPPAAAHHAESRHGWTLRQEITVTSKFRGKYLSIMPLGTIHCVFHNSGNHYTWKKVTTTVHNIIVGKLWIDQEREIDIVNHKTGDRCKLKFAPYSYFSRDVARKVSGEVMDATGRVHYTLMGTWDERMECIPVYS-VSTVSENGGDKAADNKILLWKRNPLPKNAEYMYYFTEFALTLNAPEEGTAPSDSRHRPDQRLMENGNWDEANSEKQRLEEKQRNTRKKREAERERAGEDGSP--VDTYKPMWFERKMDPVSKEMTHICRGIYWECKERQDWASCPDIF 737 HSP 2 Score: 132.109 bits (331), Expect = 5.363e-31 Identity = 74/224 (33.04%), Postives = 131/224 (58.48%), Query Frame = 3
Query: 135 TNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDSNEL----VNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE 794
+ +L+G + L+ G R Q M CRGTIN+ A I++ DS +FVIS+ G QT+HLK+ +E E +RW +AL A+ +A + D++ E S++ V+ + L+G +ED+ D++ + LQ+S+ +L+ + + E + K+K + ERAT+FR+++ +++ +C + +++W++ + ER+QR R+E +E LAKQH HLE
Sbjct: 32 STFLRGGSEFLAFLREGGAGESREQKAMRHTCRGTINLATANISVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKARAVKMQAESDDSGDEDPSSQTDKAEVHSTLRALSGKVEDLGTCNDLIAKHGTALQRSLSELESLR---LPQESSEKIKQVNERATLFRITSNAMINACRDFMSLAESHSKRWQRALQYERDQRLRLEETLEQLAKQHNHLE 252
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbp2 (oxysterol binding protein 2 [Source:MGI Symbol;Acc:MGI:1921559]) HSP 1 Score: 430.639 bits (1106), Expect = 4.426e-142 Identity = 207/423 (48.94%), Postives = 281/423 (66.43%), Query Frame = 3
Query: 1269 NTSNIATFSEVIPIRS-KRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVE-----ILKLDGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ N+ + +P S K RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA +C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR +D G R EQ+ HHPPS A H S W W + ++++KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T+D+C L + PYS FS + ++VTG ++D VL+G+WD+++E ++ ++ + GR + + LLW++YPLP N + YYFS A+TLNE E+ +APTDSR RPDQ+LME G+WDEAN EK RLEE+QR R G +E + Y PLWF+ DP + G YWE K KKDW MC IF
Sbjct: 33 SADNVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEANTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF 455
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbp2 (oxysterol binding protein 2 [Source:MGI Symbol;Acc:MGI:1921559]) HSP 1 Score: 430.639 bits (1106), Expect = 1.797e-141 Identity = 207/423 (48.94%), Postives = 281/423 (66.43%), Query Frame = 3
Query: 1269 NTSNIATFSEVIPIRS-KRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVE-----ILKLDGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+ N+ + +P S K RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA +C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR +D G R EQ+ HHPPS A H S W W + ++++KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T+D+C L + PYS FS + ++VTG ++D VL+G+WD+++E ++ ++ + GR + + LLW++YPLP N + YYFS A+TLNE E+ +APTDSR RPDQ+LME G+WDEAN EK RLEE+QR R G +E + Y PLWF+ DP + G YWE K KKDW MC IF
Sbjct: 75 SADNVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEANTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF 497
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbp (oxysterol binding protein [Source:MGI Symbol;Acc:MGI:97447]) HSP 1 Score: 432.95 bits (1112), Expect = 2.271e-138 Identity = 216/410 (52.68%), Postives = 284/410 (69.27%), Query Frame = 3
Query: 1314 SKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS----NTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQR----SRRVEILKL--DGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+K+ +RT+IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LD+AA C+N +EQ+ YVAAFTVSSY+ T +R +KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H ES N W + +++KFRGKY+ I P+G H +F + +HY W+++ T+HNIIVG++WID GE+DI+N T DKC+L + PYS FS D ++VTG +TD V L GTWDEK++ V + N + R + A E+S ++LW+R PLP N + YYFS A+TLN E APTDSR RPDQ+LME G+WDEAN EK RLEE+QR R E K DGT YK LWF+ DP + T+ ++G+YWECK K+DW C IF
Sbjct: 399 TKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSICEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHSTGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQAASGENGGDARQRGHEA-EDSRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAAKATEDGTPH--DPYKALWFERKKDPVTRELTHIYSGEYWECKEKQDWGSCPDIF 805 HSP 2 Score: 186.037 bits (471), Expect = 2.500e-48 Identity = 116/299 (38.80%), Postives = 175/299 (58.53%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNND-----SELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINP--------NQEPSADEDVSDED----FYDAFESQEGVFNVTLPSPEINLG 959
+G+L+KWTNY+KGYQ+RWFVL NGLLSYYR+++EM CRGTIN+ A I + DS +F+IS+ G QT+HLK+ +E E +RW +AL A+ KA +L D++ S+ D EL + L+ +ED+ D++ + LQ+S+ +L+ K + E K+K + ERAT+FR+++ +++ +C + ++KW+K + ER+QR R+E +E LAKQH HLE + L NP +Q S D+SDED F+DA E +T+P NLG
Sbjct: 90 EGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDDSGDEESVSQTDKTEL-QSTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLK---LPAESNEKIKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATV----LPANPPGSAGSGKDQCCSGKGDMSDEDDENEFFDAPEI------ITMPE---NLG 371
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbp2 (oxysterol binding protein 2 [Source:MGI Symbol;Acc:MGI:1921559]) HSP 1 Score: 434.491 bits (1116), Expect = 7.855e-138 Identity = 207/420 (49.29%), Postives = 280/420 (66.67%), Query Frame = 3
Query: 1278 NIATFSEVIPIRS-KRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVE-----ILKLDGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
N+ + +P S K RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA +C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR +D G R EQ+ HHPPS A H S W W + ++++KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T+D+C L + PYS FS + ++VTG ++D VL+G+WD+++E ++ ++ + GR + + LLW++YPLP N + YYFS A+TLNE E+ +APTDSR RPDQ+LME G+WDEAN EK RLEE+QR R G +E + Y PLWF+ DP + G YWE K KKDW MC IF
Sbjct: 489 NVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEANTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF 908 HSP 2 Score: 157.918 bits (398), Expect = 4.116e-39 Identity = 94/240 (39.17%), Postives = 142/240 (59.17%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXX-------------GCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE 794
KG+L KWTNYLKGYQ+RWFVL NGLLSYYRNQ EMA CR TIN+ + DS ++ + G +T+HLK+ +E + + W +AL A+ KA ++K ++SEL + + LKLN D+ D++ + LQ+S+++LD K + GE KLK + ERAT+FR+++ +++ +C + E + KW++ ++ E+EQR +E +E LAKQH LE
Sbjct: 183 KGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRATINLASTHFETEDSCGILLCN-GARTYHLKASSEVDRQHWITALELAKAKAIRVMKTQSDDSGDDDEEPAAPADNSEL--HHTLKTLSLKLN----DLSTCNDLIAKHGAALQRSLNELDSLKIPSECGE---KLKVVNERATLFRITSNAMINACRDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLE 412
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Match: Osbpl3 (oxysterol binding protein-like 3 [Source:MGI Symbol;Acc:MGI:1918970]) HSP 1 Score: 280.026 bits (715), Expect = 4.564e-81 Identity = 155/396 (39.14%), Postives = 234/396 (59.09%), Query Frame = 3
Query: 1314 SKRTRRTQIP-PKPNIN-MNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRIN-KPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCH--LSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIE----EDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECK 2474
++ RRT +P P PN + ++LWS+++N IGKDLSK+ MPV +EP++ LQRL E+ EYS +LDKA+ +P+E++ YVAAF +S+YA++ +R KPFNP+LGETYE R D G++ FAEQ+ HHPP A H ES +V W D NKF GK ++I PIG H+ H+ W ++ IHNI+ G+ WI+++GE+DI NL +D CH +++ +S + + G + D+ L G W E + Y SS +W+ P+P +++YY F+ FA+ LNE++ + PTD+R RPDQ+L+EEG +EA +K R+E+ QR RR +L+ +G E++P +F +D + NG Y E +
Sbjct: 440 ARSKRRTSLPAPGPNTSSVSLWSILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKASRIPSPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDK-GFQFFAEQVSHHPPISACHAESGNFVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIDIKNL-NDDSCHCKVNFIKAKYWSTNA-HEIEGTVFDRSGKAVHRLFGKWHESI----------------YCGGASSSTCVWRANPMPKGYEQYYGFTQFALELNEMDPLSRSLLPPTDTRFRPDQRLLEEGNIEEAEVQKQRIEKLQRERR-RVLEENGV-----EHQPRFFRKSSD-----DAWVSNGTYLELR 805
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|P22059|OSBP1_HUMAN (Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1) HSP 1 Score: 439.113 bits (1128), Expect = 7.851e-140 Identity = 233/463 (50.32%), Postives = 305/463 (65.87%), Query Frame = 3
Query: 1185 NQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPI---------RSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLE---AKNVIS-NTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQR----SRRVEILKL--DGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
N+ + ++IT N HK SNI+ S I + +K+ +RT+IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LD+AA C+N +EQ+ YVAAFTVSSY+ T +R +KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H ES N W + +++KFRGKY+ I P+G H +F + +HY W+++ T+HNIIVG++WID GE+DI+N T DKC+L + PYS FS D ++VTG +TD V L GTWDEK+E + VI N + R + A EES ++LW+R PLP N + YYFS A+TLN E APTDSR RPDQ+LME G+WDEAN EK RLEE+QR R E +K DGT Y+ YK LWF+ DP K T+ + G+YWECK K+DWS C IF
Sbjct: 357 NEFFDAPEIITMPENLGHKRTG--------SNISGASSDISLDEQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMECFKVQPVIGENGGDARQRGHEA-EESRVMLWKRNPLPKNAENMYYFSELALTLNAWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTP---YDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWSSCPDIF 807 HSP 2 Score: 187.578 bits (475), Expect = 5.753e-48 Identity = 114/295 (38.64%), Postives = 178/295 (60.34%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNND-----SELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE--YQISSSVQNQLKLNINPNQEP--SADEDVSDED----FYDAFESQEGVFNVTLPSPEINLG 959
+G+L+KWTNY+KGYQ+RWFVL NGLLSYYR+++EM CRGTIN+ A I + DS +F+IS+ G QT+HLK+ +E E +RW +AL A+ KA +L D + S+ D EL N + L+ +ED+ D++ + LQ+S+ +L+ K + E K+K + ERAT+FR+++ +++ +C + ++KW+K + ER+QR R+E +E LAKQH HLE ++ ++ + N+ ++ S D+SDED F+DA E +T+P NLG
Sbjct: 92 EGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQN-TLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLK---LPAESNEKIKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPANTPGNVGSGKDQCCSGKGDMSDEDDENEFFDAPEI------ITMPE---NLG 373
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q969R2|OSBP2_HUMAN (Oxysterol-binding protein 2 OS=Homo sapiens OX=9606 GN=OSBP2 PE=1 SV=2) HSP 1 Score: 440.654 bits (1132), Expect = 3.291e-139 Identity = 211/426 (49.53%), Postives = 281/426 (65.96%), Query Frame = 3
Query: 1278 NIATFSEVIPIRSKRT-RRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETV-----KGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVY--------EYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
N+ + ++P S + RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR DD G R EQ+ HHPPS A + S W W + ++S+KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T D+C L + PYS FS + ++VTG ++D VL+G+WDE++E V+ ++ + K +T T S+ LLW++YPLP N + YYFS A+TLNE EE +APTDSR RPDQ+LME+G+WDEAN EK RLEE+QR R L+ G Y PLWF+ DP + G YWE K K+DW MC IF
Sbjct: 492 NVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQT-LSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF 916 HSP 2 Score: 164.851 bits (416), Expect = 2.234e-40 Identity = 93/241 (38.59%), Postives = 147/241 (61.00%), Query Frame = 3
Query: 108 NIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXX------XGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSS 812
+ +G+L KWTNYLKGYQ+RWFVL NGLLSYYRNQ EMA CRGTIN+ A I+ DS +++ SG +++HLK+ +E + ++W +AL A+ KA ++ G D+ + ++ + L+ L+D+ D++ + LQ+S+ +LD K + GE KLK + ERAT+FR+++ +++ +C + E + KW++ + E+EQR +E +E LAKQH LE S+
Sbjct: 184 SFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLT-SGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGE---KLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA 420
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|P16258|OSBP1_RABIT (Oxysterol-binding protein 1 OS=Oryctolagus cuniculus OX=9986 GN=OSBP PE=1 SV=1) HSP 1 Score: 435.647 bits (1119), Expect = 1.377e-138 Identity = 230/463 (49.68%), Postives = 303/463 (65.44%), Query Frame = 3
Query: 1185 NQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPI---------RSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVI----SNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQR----SRRVEILKL--DGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
N+ + ++IT N HK SNI+ S I + +K+ +RT+IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LD+AA C+N +EQ+ YVAAFTVSSY+ T +R +KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H ES N W + +++KFRGKY+ I P+G H +F + +HY W+++ T+HNIIVG++WID GE+DI+N T DKC+L + PYS FS D ++VTG +TD V L GTWDEK++ V N + R + A EES ++LW+R PLP N + YYFS A+TLN E APTDSR RPDQ+LME G+WDEAN EK RLEE+QR R E +K DGT Y+ YK LWF+ DP K T+ + G+YWECK K+DW+ C IF
Sbjct: 359 NEFFDAPEIITMPENLGHKRTG--------SNISGASSDISLDEQYKHQLEETKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQPVSGENGGDARQRGHEA-EESRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAMKATEDGTP---YDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWNSCPDIF 809 HSP 2 Score: 186.422 bits (472), Expect = 1.371e-47 Identity = 114/295 (38.64%), Postives = 172/295 (58.31%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNND-----SELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSS----VQNQLKLNINPNQEPSADEDVSDED----FYDAFESQEGVFNVTLPSPEINLG 959
+G+L+KWTNY+KGYQ+RWFVL NGLLSYYR+++EM CRGTIN+ A I + DS +F+IS+ G QT+HLK+ +E E +RW +AL A+ KA +L D + S+ D EL N + L+ +ED+ D++ + LQ+S+ +L+ K + E K+K + ERAT+FR+++ +++ +C + ++KW+K + ER+QR R+E +E LAKQH HLE + +Q S D+SDED F+DA E +T+P NLG
Sbjct: 94 EGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQN-TLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLK---LPAESNEKIKQVNERATLFRITSNAMINACRDFLVLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPAHTSGSAGSGKDQCCSGKGDMSDEDDENEFFDAPEI------ITMPE---NLG 375
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q3B7Z2|OSBP1_MOUSE (Oxysterol-binding protein 1 OS=Mus musculus OX=10090 GN=Osbp PE=1 SV=3) HSP 1 Score: 432.95 bits (1112), Expect = 1.588e-137 Identity = 216/410 (52.68%), Postives = 284/410 (69.27%), Query Frame = 3
Query: 1314 SKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS----NTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQR----SRRVEILKL--DGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+K+ +RT+IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LD+AA C+N +EQ+ YVAAFTVSSY+ T +R +KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H ES N W + +++KFRGKY+ I P+G H +F + +HY W+++ T+HNIIVG++WID GE+DI+N T DKC+L + PYS FS D ++VTG +TD V L GTWDEK++ V + N + R + A E+S ++LW+R PLP N + YYFS A+TLN E APTDSR RPDQ+LME G+WDEAN EK RLEE+QR R E K DGT YK LWF+ DP + T+ ++G+YWECK K+DW C IF
Sbjct: 399 TKKEKRTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAKCENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSICEQVSHHPPAAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHSTGHHYTWKKVTTTVHNIIVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKMDCFKVQAASGENGGDARQRGHEA-EDSRVMLWKRNPLPKNAENMYYFSELALTLNAWEGGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKREAEAAKATEDGTPH--DPYKALWFERKKDPVTRELTHIYSGEYWECKEKQDWGSCPDIF 805 HSP 2 Score: 186.037 bits (471), Expect = 1.749e-47 Identity = 116/299 (38.80%), Postives = 175/299 (58.53%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNND-----SELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINP--------NQEPSADEDVSDED----FYDAFESQEGVFNVTLPSPEINLG 959
+G+L+KWTNY+KGYQ+RWFVL NGLLSYYR+++EM CRGTIN+ A I + DS +F+IS+ G QT+HLK+ +E E +RW +AL A+ KA +L D++ S+ D EL + L+ +ED+ D++ + LQ+S+ +L+ K + E K+K + ERAT+FR+++ +++ +C + ++KW+K + ER+QR R+E +E LAKQH HLE + L NP +Q S D+SDED F+DA E +T+P NLG
Sbjct: 90 EGWLFKWTNYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDDSGDEESVSQTDKTEL-QSTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELESLK---LPAESNEKIKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATV----LPANPPGSAGSGKDQCCSGKGDMSDEDDENEFFDAPEI------ITMPE---NLG 371
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Match: sp|Q5QNQ6|OSBP2_MOUSE (Oxysterol-binding protein 2 OS=Mus musculus OX=10090 GN=Osbp2 PE=1 SV=1) HSP 1 Score: 434.491 bits (1116), Expect = 5.494e-137 Identity = 207/420 (49.29%), Postives = 280/420 (66.67%), Query Frame = 3
Query: 1278 NIATFSEVIPIRS-KRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVE-----ILKLDGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
N+ + +P S K RR +IP KPN ++NLWS++KNCIG++LS+IPMPVNF+EP+SMLQRL ED EY +LDKA +C + +EQ+ VAAF+VSSY+ T +RI KPFNP+LGET+ELDR +D G R EQ+ HHPPS A H S W W + ++++KFRGKYI I P+G HL F+ S HYVW + T+HNIIVG++WID G+++I+N T+D+C L + PYS FS + ++VTG ++D VL+G+WD+++E ++ ++ + GR + + LLW++YPLP N + YYFS A+TLNE E+ +APTDSR RPDQ+LME G+WDEAN EK RLEE+QR R G +E + Y PLWF+ DP + G YWE K KKDW MC IF
Sbjct: 489 NVLDGASFMPKNSCKVKRRVRIPDKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVNCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRMEDMGLRSLCEQVSHHPPSAAHHVFSKHGWSLWQEITIASKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTKDRCQLKFVPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDDQMECSKIVHSSPSSDGRQKTVYQTLPAKLLWRKYPLPENAENMYYFSELALTLNEQEDGVAPTDSRLRPDQRLMERGRWDEANTEKQRLEEKQRLSRRRRLESCTAGCGGEEEKESDGYVPLWFEKRLDPLTGEMACMYKGGYWEAKEKKDWHMCPNIF 908 HSP 2 Score: 157.918 bits (398), Expect = 2.879e-38 Identity = 94/240 (39.17%), Postives = 142/240 (59.17%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXX-------------GCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE 794
KG+L KWTNYLKGYQ+RWFVL NGLLSYYRNQ EMA CR TIN+ + DS ++ + G +T+HLK+ +E + + W +AL A+ KA ++K ++SEL + + LKLN D+ D++ + LQ+S+++LD K + GE KLK + ERAT+FR+++ +++ +C + E + KW++ ++ E+EQR +E +E LAKQH LE
Sbjct: 183 KGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRATINLASTHFETEDSCGILLCN-GARTYHLKASSEVDRQHWITALELAKAKAIRVMKTQSDDSGDDDEEPAAPADNSEL--HHTLKTLSLKLN----DLSTCNDLIAKHGAALQRSLNELDSLKIPSECGE---KLKVVNERATLFRITSNAMINACRDFLELAETHSRKWQRALNYEQEQRVHLEETIEQLAKQHNSLE 412
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A504XP16 (Oxysterol-binding protein OS=Fasciola gigantica OX=46835 GN=FGIG_00040 PE=3 SV=1) HSP 1 Score: 713.375 bits (1840), Expect = 0.000e+0 Identity = 378/884 (42.76%), Postives = 522/884 (59.05%), Query Frame = 3
Query: 108 NIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXX-------------------------------XGCDNNDSEL--------DSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPSPEINLGVSLPSRCXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFFIGDSSTRGFE-EVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIA--TFSEVIPIRS-KRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVY----------------------------------------EYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+++G+L+KWTNY+KGYQKRWF+LQNGLLSYYRNQ+EMA CRGTIN+ NA + ST+F+IS+S QTFHLK+ ESE K W S LL A+ KA L D++D E D+ LVN + K+ HL D+++ Q+ L K DDLQ+S+ DL+ ++ E + ++ER+T+F V++ +++ +CA +A S + +WR++ +S+RE+ +E M+E+LAKQ R LE + QN L ++ + ++D S G++ S + S + + S + + Y + + D E ++ +++ + L+EARVI + L+ + + + +L S N T + ++P RS R RRT IPP+PN ++NLWS++KNCIGK+L+KIPMPVNFSEP+SMLQRL EDFEYSS LD+AA CQ+ +EQ+++VAAFTVS+YA TA R+NKPFNPLLGETYE DRTDD GWR AEQ+ HHPP CA+HCESN W CWF+FSM+ KFRGKY+QI+P+G CHL+F+ + +HY W++IP+T+HNIIVGR+WIDN GEMDIIN +T +KCHLSYK YS FS++TP+RVTGAITDK V VLNGTWDE +E V++ + G+ L T + I WQR PLPP+ ++ +YF+ FA+ LNE E + PTD R RPDQ+LME GKWDEAN+EK LEE+QR RR +I K ++P+WF+ D + + FNGKYWE K +DWSMC I+
Sbjct: 8 SLRGFLFKWTNYIKGYQKRWFILQNGLLSYYRNQAEMAHTCRGTINLANATVASTGSTTFLISNSSTQTFHLKAACESEQKMWVSVLLTAKSKALALRKYGKLFCSFLRVIFRISVNLERRLSDDSDVYTEGDDDDVEYKNSSMSADDAMRLVNQLLAKMEQHLVDLQRHQETLGHKGDDLQRSLADLETARDPT---EATQRFSVVRERSTVFGVASLAMVNACAEFASSGRRQTHRWRRIFNSQRERCALLEQMIEELAKQLRQLETLVK---QNNLHTSLQLSTGGTSDRTES--------------------------GMASSSHLTGRSDSASMMSTSLGDENNGIPSVNDVAYEYESDVYGSDDDEDDAENQMKVQKTRKPLREARVIQPRMRRHDSRSATLVPSGDRSSDRKSDLNSELSQAQNETRNTDTTLVPTRSLSRPRRTTIPPRPNYSLNLWSIMKNCIGKELTKIPMPVNFSEPLSMLQRLTEDFEYSSCLDRAAQCQDTLEQMAHVAAFTVSAYATTAVRVNKPFNPLLGETYECDRTDDRGWRSLAEQVSHHPPKCALHCESNAWYCWFEFSMNTKFRGKYLQINPVGTCHLVFRNTGHHYTWQKIPLTVHNIIVGRLWIDNSGEMDIINHSTGEKCHLSYKAYSYFSSETPRRVTGAITDKSGAVRYVLNGTWDESMEYAPVVTTRQPRNGKPILETGPARI-AWQRNPLPPDSERMHYFTLFALQLNEEEPGVCPTDCRLRPDQRLMEVGKWDEANREKVVLEEKQRHRRRQIAASLAAKTLGLPDAASGHSDVNPSRRGSVAQSDISALTPSVVSSFLDQADSAHRPMWFERQFDQDTGEAIFAFNGKYWEKKVIQDWSMCPDIY 858
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A564YHR5 (Oxysterol-binding protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS6057 PE=3 SV=1) HSP 1 Score: 697.967 bits (1800), Expect = 0.000e+0 Identity = 396/893 (44.34%), Postives = 524/893 (58.68%), Query Frame = 3
Query: 102 SSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSEL-------------------DSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPS------------------------------------------ADEDVSDEDFYDAFE-SQEGVFNVTLPSPEINLGVSLPSRCXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFFIGDSSTRGFEEVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLN---EIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEI-LKLDGTK------------------------EFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
S+N+KGYL KWTNYLKGYQKRWFVLQNGLLSYYRNQ+E+ CRGTIN+ NAKI + VIS+S QTFHLK+ NE E K+W +AL + A L K +++D D+ +LV G I + D++ QD L RK D+LQK I+DL+ S+I ++A K+ +++RAT+++V++ ++ SC+ + E + +WRK+ +++ ++R R+E MVE+LAKQ LE Q+ S N I P Q + A ED D DFYDA E + F+V LPS P S+ + E E V+ S SD G + + Y + D+ +G + N+ A VI K + R T SS+ S A +IP+R RRT IPPKPNI++NLWS + NCIGK+L+KIPMPVNFSEP+SMLQRL+E+FEYS +LD+AA+C NP+EQ++YV+AF VSSYA+TA R+ KPFNPLL ETYE DRTDD GWR AEQ+ HHPP A HCES+ W WFDFS+S KFRG+Y+QI G CHL+F+++ YHY W +IP+T+HNIIVGR+WI+N GE+DIIN TT DKCHL++K YS FS++ P+RVTGA+TDK V ++ GTWDE +E VI++ + + T + LW+ PLPP DK Y F+ FA+ LN E E ++ PTDSR RPDQ+LMEEG WDEAN EK RLEE+QR RR E+ LKL GT +KPLWF+ V D + +T KFNGKYW+CK K DWS+C ++
Sbjct: 6 SANLKGYLLKWTNYLKGYQKRWFVLQNGLLSYYRNQAEVTHTCRGTINLANAKIVSAGHLTLVISNSSTQTFHLKATNEMEQKKWMAALTMGKANALSLGKSGNDSDDWDEADDDESDLAWSAPRLMPEDAAKLVEGAISNFESRIGDLQHYQDTLKRKADELQKVINDLE---GSDISSDLAEKISIVQDRATVYKVASLAMANSCSDFLEFARSQMRRWRKIFNTQVDRRARLEQMVEELAKQINKLESQVRSKSMNPGNWGI-PGQAVAVRRTSAETARARGATLSSNHGNSVRLTTDGSSSGPPGISSAIASEDEED-DFYDAAEDAGADEFDVILPSTN---SCPYPGPLSQTAAEKEGMVDARQSQTSDVPVGADVNMEYESDIEDSDTDDQGKGQQENR--------AHVIQ-KHAWGKAGRSPKETGSSSYA-----------GPSRSAPEKRIIPVRKPVQRRTSIPPKPNISLNLWSFLSNCIGKELTKIPMPVNFSEPLSMLQRLSENFEYSYVLDRAAACTNPLEQLAYVSAFVVSSYASTALRVAKPFNPLLNETYECDRTDDLGWRSVAEQVSHHPPVAAFHCESDLWYTWFDFSISTKFRGRYLQIKVNGVCHLVFRKTGYHYTWTKIPLTVHNIIVGRLWIENSGEIDIINHTTGDKCHLTFKQYSYFSSEVPRRVTGAVTDKTGKVHGIIGGTWDEFIEYAPVITDNTGSSNKHVIETG-PPVQLWRVSPLPPGADKMYNFTQFAMQLNNRPEDEPNLCPTDSRLRPDQRLMEEGLWDEANAEKVRLEEKQRMRRREMALKLLGTDGADSAAAVGGSVASSTPLPAALMDTLDQTHKPLWFEKVVDEDTGLETLKFNGKYWKCKEKNDWSVCPDLY 869
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: A0A0R3X2E0 (Oxysterol-binding protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS7436 PE=3 SV=1) HSP 1 Score: 686.026 bits (1769), Expect = 0.000e+0 Identity = 374/878 (42.60%), Postives = 521/878 (59.34%), Query Frame = 3
Query: 102 SSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYY-RNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRW-TSXXXXXXXXXXXXXXGCDNNDSEL-----------------DSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNI-----NPNQE-----------------------------PSADEDVS------DEDFYDAFESQEGVFNVTLPSPEINLGVSLPSRCXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFFIGDSSTRGFEEVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEI---EEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKL--------DGTKEFVYE-----YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
SSN+KGYL KWTNY+KGYQKRWFVLQNGLLSYY RNQSE+ CRGTIN+ NAKI + VIS+S QTFHLK+ NE E K+W T+ + G D++D + D LV + + D++ Q+ L RK D+LQ+SI++LD N+ + + N+ ++AT+++V++ +++ SC+ + + + ++WR++ ++ ++R +E MVE+LAKQ R LE Q + + + I P Q P A VS ++DFYDA + + F+V LP+ ++ S ++++L S + + + + D+ GD+ EE + R K+A VI R +A ++ I S ++A +IP+R RRT IPPKPNI++NLWS++ NCIGK+L+KIPMPVNFSEP+SMLQRL+E+FEYS +LD+AA+C +P+EQ++YV+AF VSSYA+TA R+NKPFNPLL ETYE DRTDD GWR AEQ+ HHPP A HCES+ W WFDFS+S KFRG+Y+QI G CHL+F+++ YHY W +IP+T+HNIIVG++WI+N GE+DI N T DKCHL++KPYS FS+D P+RVTGA++DK V ++NGTWDE +E V+++ + G + + LW+ PLPP DK Y F+ FAI LN+ E ++ PTDSR RPDQ+LMEEG WDEAN EK RLEE+QR RR ++ + DG V + +KPLWF+ DP+ +T KF G+YWE KAK DWSMC +F
Sbjct: 7 SSNLKGYLLKWTNYIKGYQKRWFVLQNGLLSYYSRNQSEVTHTCRGTINLANAKIVSTGHLTLVISNSSSQTFHLKAANEIEQKKWMTALTMGKANALALGKSGDDSDDWDDGEDDNDIAWSSPRLVPEDGARLVEHALSHFENRINDLQHYQETLKRKADELQRSINELDA---CNLPPDQIEIICNVMDKATVYKVASLAMVNSCSDFLDFARTQTKRWRRIFSAQVDRRAHLEQMVEELAKQIRKLEIQARNKSMHSGGVCILRSWAIPGQAVLVRRTSTETTRTRSTTLGACSGGGSGLPPCASTAVSSITSDDEDDFYDAQDVEGCEFDVILPTTS-TFAIAEKSSMTDIALPNSSTASIPVGSDLAMEYESDTA----DSDLGGDA-----EETEKGQQKFRGKQAHVIQ----KHAWGRAGRASAQPESLPAVIPGKSGAEAGVSVAADRRIIPVRKPVQRRTTIPPKPNISLNLWSILSNCIGKELTKIPMPVNFSEPLSMLQRLSENFEYSYVLDRAATCADPVEQLAYVSAFVVSSYASTALRVNKPFNPLLNETYECDRTDDLGWRSLAEQVSHHPPVAAFHCESDLWYTWFDFSISTKFRGRYLQIKVNGVCHLVFRKTGYHYTWTKIPLTVHNIIVGKLWIENSGEIDITNHKTGDKCHLTFKPYSYFSSDIPRRVTGAVSDKSGKVHGIINGTWDEFIEYAPVVTDKLSTGGEKPVLETGPPVQLWRVSPLPPEADKMYNFTQFAIQLNDKPNNEPNLCPTDSRLRPDQRLMEEGFWDEANVEKVRLEEKQRLRRRQMALMLINRESSSDGASSTVADTLDEAHKPLWFEKEVDPDTGLETMKFTGRYWEIKAKNDWSMCPDLF 867
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: W6UQH0 (Oxysterol-binding protein OS=Echinococcus granulosus OX=6210 GN=EGR_01540 PE=3 SV=1) HSP 1 Score: 683.715 bits (1763), Expect = 0.000e+0 Identity = 377/884 (42.65%), Postives = 523/884 (59.16%), Query Frame = 3
Query: 102 SSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSEL------------------DSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQI--------SSSVQNQLKL--------------------NINPNQEPSADEDVS------DEDFYDAFESQEGVFNVTLPSPEINLGVSLPSRCXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFFIGDSSTRGFEEVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEI---EEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEI-LKL-------DGTKEFVY------------------EYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
SSN++GYL KWTNY+KGYQ+RWFVLQNGLLSYYRNQSE+ CRGTIN+ NAKI + VIS+S QTFHLK+ NE E K+W +AL + A L K D++D D LV + + D++ QD L RK DDLQ+SI++LD N+ ++ K+ N+ ++AT+++V++ +++ SC+ + + ++WR++ +++ ++R +E M+E+LAKQ R LE Q S ++ Q L P A VS ++DFYDA + ++ F+V LP+ + PS + S + + + +S + D+ GD+ +E + R K+A VI K + R S ++ V TS +A +IP+R RRT IPPKPNI++NLWS++ NCIGK+L+KIPMPVNFSEP+SMLQRL+E+FEYS +LD+AA+C +P+EQ++YV+AF VSSYA+TA R+NKPFNPLL ETYE DRTDD GWR AEQ+ HHPP A HCES+ W WFDFS+S KFRG+Y+QI G CHL+F+++ YHY W +IP+T+HNIIVG++WI+N GE+DI N T DKCHL++KPYS FS+D +RVTGA++D+ V ++NGTWDE +E V++NT + G + + LW+ PLPP DK Y F+ FAI LN+ E ++ PTDSR RPDQ+LMEEG WDEAN EK RLEE+QR RR ++ LKL DG +KPLWF+ DP+ +T +F G+YWE K K +WSMC ++
Sbjct: 7 SSNLRGYLLKWTNYIKGYQRRWFVLQNGLLSYYRNQSEVTHTCRGTINLANAKIVSTGHLTLVISNSSSQTFHLKAANEIEQKKWMTALTMGKADALALGKSGDDSDDWDDGEDENDIAWSSPRLMPEDGARLVEHALSHFENRVNDLQHYQDTLKRKADDLQRSINELDA---CNLPPDLIEKICNVMDKATVYKVASLAMVNSCSDFLGFARTQTKRWRRIFNAQVDRRAHLEQMIEELAKQIRKLEIQARNKSVHSGSWAIPGQAVLVRRTSTETTRTRSTTLGTCSGGGAGLPPCASTAVSSITSDDEDDFYDAQDVEDCEFDVILPTTSTSAVTEKPSMINAASPSSTASIPVGTDLAMEYES------DTADSELEGDT-----DETEKGQQKFRGKQAHVIQ-KHTWGRAGRASAQPESPPSVAP--GKVGAEAGTS-VAPERRIIPVRKPVQRRTTIPPKPNISLNLWSILSNCIGKELTKIPMPVNFSEPLSMLQRLSENFEYSYVLDRAAACADPLEQLAYVSAFVVSSYASTALRVNKPFNPLLNETYECDRTDDLGWRSVAEQVSHHPPVAAFHCESDLWYTWFDFSISTKFRGRYLQIKVNGVCHLVFRKTGYHYTWTKIPLTVHNIIVGKLWIENSGEIDITNHKTGDKCHLTFKPYSYFSSDIARRVTGAVSDRSGKVHGIINGTWDEFIEYAPVVTNTLSTGGEKPILETGPPVQLWRVSPLPPEADKMYNFTQFAIQLNDRPDNEPNLCPTDSRLRPDQRLMEEGLWDEANVEKVRLEEKQRLRRRQMALKLINKESSSDGAPSTAGTSASSANVPASLMDTLDEAHKPLWFEKGVDPDTGLETMRFTGRYWESKEKNNWSMCPDLY 872
BLAST of Oxysterol-binding protein vs. TrEMBL
Match: R7TZ29 (PH domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_179200 PE=4 SV=1) HSP 1 Score: 679.863 bits (1753), Expect = 0.000e+0 Identity = 367/817 (44.92%), Postives = 501/817 (61.32%), Query Frame = 3
Query: 102 SSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNND---SELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLP---SPEINLGVSLPSRCXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFFIGDS--STRGFEEVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESN--EWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKL---DGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
S KG++YKWTNY+KGYQKRWFVLQNGLLSYYRNQ+EM+ CRGTIN+ NA I+ DS SFVIS+ G QTFHLK+ +E E +RW +AL A+ KA +LL+ D ++ ++ D NEL N I L+ LED+ D++ + LQK++ +L++ + ++ E + K K++ ERAT+FR+++ +++ +C Y E + ++W+K++ SE EQ+ R+E MVE LAKQH+ +E Q S+ + + Q ED D DF+DA + F V LP G+S+ S IG++ T + S+ S R EA+VIS K ++ + + + + P SLT +V SKR RR IP +PN ++NLWS++KNCIGK+LSKIPMPVNFSEP+S LQR+ EDFEYS L KAA C + EQ++Y+AAFT+SSYA T R KPFNPLLGET+E DR DD GWR FAEQ+ HHPP A+H ES +W W +F+MS+KFRGKY+QI P+G HLLF ++ HY W ++ T+HNIIVG++W+DNHGEMDI N D CHL Y YS F+ +TP++VTG ITD VL GTWDE++EA VI E+ KG+ T E+ ++ +RYP +K Y+F+ A+ LNEIEE +APTDSRNRPDQ++MEEG+WDEAN++K LEE+QR+ R E + E Y+ Y+P WF DP + Y + G+YW+CK K DWS C I+
Sbjct: 9 SDQYKGWVYKWTNYIKGYQKRWFVLQNGLLSYYRNQAEMSHTCRGTINLANAFIHTEDSCSFVISNGGTQTFHLKASSEVERQRWVTALELAKNKAINLLESDDEDEETHTQPDKNELQN-TIRTLSAKLEDLSTCNDLITKHGAALQKALGELEQIEAAS---EASAKFKSVNERATLFRITSNAMINACHDYLELAQTQGKRWQKLLQSEHEQKLRLEEMVEQLAKQHQSIEKQARKSLAHANHSSSGNTQGAEGSEDEED-DFFDAVDDHTEEFKVCLPPQTHKRTGSGISVDS--------------------------------------IGETLGPTADNYDSSDTDSESRGAEAKVISHKHGHKRTHSRDQMLKEGGSSSMPSTPNSLT----------KVAHPGSKRQRRMLIPERPNYSINLWSIMKNCIGKELSKIPMPVNFSEPLSFLQRITEDFEYSECLMKAAQCTDSCEQLAYIAAFTISSYANTTARTGKPFNPLLGETFECDRRDDMGWRSFAEQVSHHPPILAMHTESKDRDWSSWQEFTMSSKFRGKYLQIIPLGIAHLLFPKTGNHYTWRKVTTTVHNIIVGKLWVDNHGEMDITNHHNGDNCHLKYSAYSYFARETPRKVTGVITDASGQARWVLQGTWDERVEAAKVIKTVESGKGKIVYETAEAKVMWQRRYP-SKELEKCYFFTELAVQLNEIEEGVAPTDSRNRPDQRMMEEGRWDEANEKKVLLEEKQRTVRREREREASDAAANEAEYQGYEPKWFRKDIDPVTGNPAYVYTGEYWDCKEKGDWSRCPDIY 771
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 444.891 bits (1143), Expect = 7.626e-145 Identity = 212/414 (51.21%), Postives = 279/414 (67.39%), Query Frame = 3
Query: 1296 EVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTE----TVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVY---EYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
EV+P+R +RTR IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EPISMLQRL+ED EYS +LD+ A CQ+ +EQ+ YVAAFTVSSY+ T +R KPFNPLLGET+ELDR + G+R EQ+ HHPP+ A H S W + ++++KFRGKY+ I P+G H +F +S HY W+++ T+HNIIVG++WID GE+D+IN T D+CHL + PYS FS D ++VTG +TDK VL+GTWDEK+E V+ ++ +GR + + LW++ PLP + YYF+ A+TLNE E+ +APTDSR RPDQ+LME+G WDEAN EK RLEE+QRS R E + KE Y LWF+ V D T+ + G YWE K + W C IF
Sbjct: 255 EVVPVRKRRTR---IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEANAEKQRLEEKQRSVRREREREAWAKEHGAPQDNYTALWFEQVVDEATGEPTHIYKGGYWETKEQGTWENCPDIF 665 HSP 2 Score: 137.502 bits (345), Expect = 4.309e-33 Identity = 79/242 (32.64%), Postives = 139/242 (57.44%), Query Frame = 3
Query: 216 MAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPS 941
M CRGTIN+ A I + DS +FVIS+ G QT+HLK+ +E E +RW +AL A+ KA + ++ S+L E V + L +ED+ D++ + LQ+S+ +L+ K + G+ + K++ + ERAT+FR+++ +++ +C + +++W+K + +ER+QR R+E +E LAKQH HLE + + P + ++D+D D +F+DA E + +T+P+
Sbjct: 1 MGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRMQ--AESGQSQLGFTEGVQSTLRTLGSKVEDLSTCNDLIAKHGSALQRSLSELEGVK---LGGDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLERAFRGATVLPASPSSGPGKGDASDDD--DNEFFDACEDVQEF--ITIPA 233
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 437.958 bits (1125), Expect = 5.351e-141 Identity = 211/418 (50.48%), Postives = 278/418 (66.51%), Query Frame = 3
Query: 1296 EVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTE----TVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYE-------YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
EV+P+R +RTR IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EPISMLQRL+ED EYS +LD+ A CQ+ +EQ+ YVAAFTVSSY+ T +R KPFNPLLGET+ELDR + G+R EQ+ HHPP+ A H S W + ++++KFRGKY+ I P+G H +F +S HY W+++ T+HNIIVG++WID GE+D+IN T D+CHL + PYS FS D ++VTG +TDK VL+GTWDEK+E V+ ++ +GR + + LW++ PLP + YYF+ A+TLNE E+ +APTDSR RPDQ+LME+G WDEAN EK RLEE+QRS R E + E Y LWF+ V D T+ + G YWE K + W C IF
Sbjct: 347 EVVPVRKRRTR---IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEANAEKQRLEEKQRSVRREREREAVRLASTAEEGAPQDNYTALWFEQVVDEATGEPTHIYKGGYWETKEQGTWENCPDIF 761 HSP 2 Score: 193.741 bits (491), Expect = 3.270e-51 Identity = 112/305 (36.72%), Postives = 176/305 (57.70%), Query Frame = 3
Query: 96 TLSSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDS------------NELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADE--------DVSDED---FYDAFESQEGVFNVTLPS 941
T KG+L+KWTNY+KGYQ+RWFVL NGLLSYYR Q+EM CRGTIN+ A I + DS +FVIS+ G QT+HLK+ +E E +RW +AL A+ KA + D++ E + N V + L +ED+ D++ + LQ+S+ +L+ K + G+ + K++ + ERAT+FR+++ +++ +C + +++W+K + +ER+QR R+E +E LAKQH HLE + + L +P+ P+AD D SD+D F+DA E + +T+P+
Sbjct: 10 TPGDTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRMQAESDDSGDECSTSPPSAGQGLGARNSEVQSTLRTLGSKVEDLSTCNDLIAKHGSALQRSLSELEGVK---LGGDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLE----RAFRGATVLPASPSN-PTADSKGSGPGKGDASDDDDNEFFDACEDVQEF--ITIPA 304
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 435.261 bits (1118), Expect = 1.016e-139 Identity = 213/431 (49.42%), Postives = 281/431 (65.20%), Query Frame = 3
Query: 1296 EVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTE----TVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILK-----LDGTKEFVYE---------------YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
EV+P+R +RTR IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EPISMLQRL+ED EYS +LD+ A CQ+ +EQ+ YVAAFTVSSY+ T +R KPFNPLLGET+ELDR + G+R EQ+ HHPP+ A H S W + ++++KFRGKY+ I P+G H +F +S HY W+++ T+HNIIVG++WID GE+D+IN T D+CHL + PYS FS D ++VTG +TDK VL+GTWDEK+E V+ ++ +GR + + LW++ PLP + YYF+ A+TLNE E+ +APTDSR RPDQ+LME+G WDEAN EK RLEE+QRS R E + +E V E Y LWF+ V D T+ + G YWE K + W C IF
Sbjct: 347 EVVPVRKRRTR---IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEANAEKQRLEEKQRSVRREREREAVRLASTAEEAVIEDSITDSPLKSAPQDNYTALWFEQVVDEATGEPTHIYKGGYWETKEQGTWENCPDIF 774 HSP 2 Score: 193.741 bits (491), Expect = 3.731e-51 Identity = 112/305 (36.72%), Postives = 176/305 (57.70%), Query Frame = 3
Query: 96 TLSSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDS------------NELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADE--------DVSDED---FYDAFESQEGVFNVTLPS 941
T KG+L+KWTNY+KGYQ+RWFVL NGLLSYYR Q+EM CRGTIN+ A I + DS +FVIS+ G QT+HLK+ +E E +RW +AL A+ KA + D++ E + N V + L +ED+ D++ + LQ+S+ +L+ K + G+ + K++ + ERAT+FR+++ +++ +C + +++W+K + +ER+QR R+E +E LAKQH HLE + + L +P+ P+AD D SD+D F+DA E + +T+P+
Sbjct: 10 TPGDTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRMQAESDDSGDECSTSPPSAGQGLGARNSEVQSTLRTLGSKVEDLSTCNDLIAKHGSALQRSLSELEGVK---LGGDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLE----RAFRGATVLPASPSN-PTADSKGSGPGKGDASDDDDNEFFDACEDVQEF--ITIPA 304
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp (oxysterol binding protein [Source:NCBI gene;Acc:103044970]) HSP 1 Score: 429.869 bits (1104), Expect = 1.925e-137 Identity = 215/448 (47.99%), Postives = 282/448 (62.95%), Query Frame = 3
Query: 1296 EVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTE----TVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEI------------------------LKLDGTKEFVYE-------------YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
EV+P+R +RTR IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EPISMLQRL+ED EYS +LD+ A CQ+ +EQ+ YVAAFTVSSY+ T +R KPFNPLLGET+ELDR + G+R EQ+ HHPP+ A H S W + ++++KFRGKY+ I P+G H +F +S HY W+++ T+HNIIVG++WID GE+D+IN T D+CHL + PYS FS D ++VTG +TDK VL+GTWDEK+E V+ ++ +GR + + LW++ PLP + YYF+ A+TLNE E+ +APTDSR RPDQ+LME+G WDEAN EK RLEE+QRS R E LK D EF + Y LWF+ V D T+ + G YWE K + W C IF
Sbjct: 347 EVVPVRKRRTR---IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYSELLDRGAKCQSSLEQLCYVAAFTVSSYSTTVHRTGKPFNPLLGETFELDRLQESGYRSLCEQVSHHPPAAAHHVISERGWTLRQEITVASKFRGKYLSIMPLGSIHCIFDKSNNHYSWKKVTTTVHNIIVGKLWIDQSGEIDVINHRTGDRCHLKFAPYSYFSRDVARKVTGVVTDKDGKAHYVLSGTWDEKMECSRVMQSSRGGENGTEGRQKTVYQTLKARELWRKNPLPEGAENMYYFTQLALTLNEQEDGVAPTDSRRRPDQRLMEQGMWDEANAEKQRLEEKQRSVRREREREAVRLASTAEEAVIEDSITDSPLKTDDV-EFSSDPSDSAFKSAPQDNYTALWFEQVVDEATGEPTHIYKGGYWETKEQGTWENCPDIF 790 HSP 2 Score: 193.741 bits (491), Expect = 3.930e-51 Identity = 112/305 (36.72%), Postives = 176/305 (57.70%), Query Frame = 3
Query: 96 TLSSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDS------------NELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADE--------DVSDED---FYDAFESQEGVFNVTLPS 941
T KG+L+KWTNY+KGYQ+RWFVL NGLLSYYR Q+EM CRGTIN+ A I + DS +FVIS+ G QT+HLK+ +E E +RW +AL A+ KA + D++ E + N V + L +ED+ D++ + LQ+S+ +L+ K + G+ + K++ + ERAT+FR+++ +++ +C + +++W+K + +ER+QR R+E +E LAKQH HLE + + L +P+ P+AD D SD+D F+DA E + +T+P+
Sbjct: 10 TPGDTYKGWLFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATANIAVEDSCNFVISNGGAQTYHLKASSEVERQRWITALELAKAKAVRMQAESDDSGDECSTSPPSAGQGLGARNSEVQSTLRTLGSKVEDLSTCNDLIAKHGSALQRSLSELEGVK---LGGDTSDKIRQVTERATLFRITSNAMINACRDFLALAQAHSKRWQKALQAERDQRVRLEETLEQLAKQHNHLE----RAFRGATVLPASPSN-PTADSKGSGPGKGDASDDDDNEFFDACEDVQEF--ITIPA 304
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Match: osbp2 (oxysterol binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-091113-18]) HSP 1 Score: 426.402 bits (1095), Expect = 3.249e-136 Identity = 203/415 (48.92%), Postives = 282/415 (67.95%), Query Frame = 3
Query: 1308 IRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIG---KCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTET-----VKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQ----RSRRVEI-LKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
++ +R RR++IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EYS +LD+AA C +EQ+ VAAF+VSSY+ T +R KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H S W W + ++ +KFRGKYI I P+G + F S + ++ T+HNIIVG++WID G+++I+N T+D CHL + PYS FS D P++VTG + + +L+GTWD+K+E+ ++ ++ VK +T T LLW++YPLP N + +YFSS A+TLNE EE +APTDSR RPDQ+LME G WDEAN +K RLEE+Q R+R + + L+ +E V Y+P+WF+ DP+ T+ + G YWE K K+DWS C I+
Sbjct: 374 LQQRRGRRSRIPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYSELLDRAARCSCALEQMCLVAAFSVSSYSTTVHRTGKPFNPLLGETFELDRLEESGYRSICEQVSHHPPAAAHHVMSQRGWTLWQEITIDSKFRGKYISIMPLGFHISICIFFYISATGNIHLKVTSTVHNIIVGKLWIDQSGDIEIVNRRTKDTCHLKFSPYSYFSRDVPRKVTGVVAESDGLAHYILSGTWDDKMESAKIVESSRGCVGSEVKQKTVYQTLPPK-LLWKKYPLPENAENMHYFSSLALTLNEPEEGVAPTDSRLRPDQRLMEAGLWDEANAQKQRLEERQRLERRTREAQANIALEEGRE-VEGYRPMWFEKRMDPDNGESTFIYRGGYWESKEKQDWSQCPSIY 786 HSP 2 Score: 173.326 bits (438), Expect = 2.134e-44 Identity = 103/293 (35.15%), Postives = 165/293 (56.31%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSEL----DSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE--YQISSSVQNQLKLNINPNQEPSADEDVSDE----DFYDAFESQEGVFNVTLPSPEINLGV 962
+G+L KWTNYLKGYQ+RWFVL NGLLSYYR Q+EMA CR TI++ I L D+ V++ SG +++HLK+ +E+E +RW SAL A+ A ++ D++ E+ L + L L+D+ D++ + LQ+S+ +L+ + + + KLK + ERAT+FR+++ +++ +C + + + +W+K + EREQR +E +E LAKQH LE ++ + S Q E S + D SDE +F+DA E +T+P + G+
Sbjct: 95 RGWLLKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRATISLATVHIELGDNCHLVLT-SGGRSYHLKASSEAESQRWVSALQQAKANATQMMHHSDDSGDEVLVAQPDRALTPAALKTLVSKLDDLSTCNDLIGKHGAALQRSLSELEDLRCPSDGND---KLKTVNERATLFRITSNAMINACRDFVDLAEAHSRRWQKALQYEREQRHHLEETIEQLAKQHNSLERAWREAPSTHTQ-------GSERSGEVDTSDENEDVEFFDAMEDSPAF--ITVPDTSGSYGL 374
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbp (oxysterol binding protein [Source:ZFIN;Acc:ZDB-GENE-090312-18]) HSP 1 Score: 445.277 bits (1144), Expect = 9.164e-145 Identity = 216/445 (48.54%), Postives = 293/445 (65.84%), Query Frame = 3
Query: 1218 ASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS-----NTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQR-SRRVEILKLDGTKEFVYE-------YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
AS++ + N L + +S+ + E++ K+ RR +IP KPN ++NLWS++KNCIGKDLSKIPMPVNF+EP+SMLQRL ED EY +LDKAA C++ +EQ+ YVAAF+VSSY+ T YR KPFNPLLGET+ELDR ++ G+R EQ+ HHPP+ A H +S W W + ++S+KFRGKY+ I P+G H F S HY W+++ T+HNIIVGR+WID G++DI+N T DKC L + YS FS D P++V+G + D N +L+GTWDEK+E ++ + + +T T+ + LW+RYPLP N D YYF+ A+TLNE EE +APTDSR RPDQ+LME GKWDEAN EK RLEE+QR RR +L E + Y+P+WF+ DP + + + G YWE K K++W + IF
Sbjct: 301 ASASGHLEDWNSEDLKHASSSSSLGQEMV---VKKQRRARIPDKPNYSLNLWSIMKNCIGKDLSKIPMPVNFNEPLSMLQRLTEDLEYFDLLDKAAKCESSLEQLCYVAAFSVSSYSTTVYRTGKPFNPLLGETFELDRLEECGYRSICEQVSHHPPAAAHHVDSRRGWRLWQEITVSSKFRGKYLSIIPLGTIHCEFPSSGNHYTWKKVTTTVHNIIVGRLWIDQSGDIDIVNHHTGDKCQLKFIAYSYFSRDIPRKVSGVVMDAEGNAHYILSGTWDEKMEYAKIVQSSKGSSGSEGRQKTVYQTQPAK-HLWKRYPLPENSDNMYYFTELALTLNETEEGVAPTDSRLRPDQRLMENGKWDEANAEKQRLEEKQRLVRRRREAELASAAEPNGDAGRKHQSYRPMWFERKEDPFTREVSCVYRGGYWETKEKQEWKISQDIF 741 HSP 2 Score: 189.889 bits (481), Expect = 1.070e-50 Identity = 103/233 (44.21%), Postives = 149/233 (63.95%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRW-TSXXXXXXXXXXXXXXGCDNNDSE-----LDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE 794
KG+L+KWTNY+KGYQKRWFVL NGLLSYYR Q+EMA CRGTIN+ A I+ DS + V+S+ G QT+HLK+ +E E +RW T+ LA K + + D++D E D EL + L+ LED+ D++ + LQ+S++DL+ K + E + KLK + ERAT+FR+++ +++ +C + E + +KW+K + EREQR R+E +E LAKQH LE
Sbjct: 4 KGWLFKWTNYIKGYQKRWFVLSNGLLSYYRTQAEMAHTCRGTINLAGAYIDTEDSCNIVVSNGGTQTYHLKASSEVERQRWVTALELAKAKAIRMMQAESDDSDDEKSGAQADKTEL-QTTLRSLSSKLEDLSTCNDLIGKHGAALQRSLNDLETLK---LPPEGSEKLKAVNERATLFRITSNAMINACHDFLEQAQSQGKKWQKTVQYEREQRLRLEETLEQLAKQHNSLE 232
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 252.292 bits (643), Expect = 1.899e-71 Identity = 144/397 (36.27%), Postives = 227/397 (57.18%), Query Frame = 3
Query: 1326 RRTQIP-PKPNIN-MNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRIN-KPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTED-KCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIE----EDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWS 2492
RR +P P + + + LW +++ IGKDLSK+ MPV +EP+++LQRL E+ EYS +LD+AA +P +++ VA F VS+YA+T R KPFNP+LGETYE R +D G+R AEQ+ HHPP HC+S ++V W D + NKF GK ++I P+G ++ + Y W ++ IHNI+ G+ WI+++GE+ I N + +C +++ S +S++ +V G + D+ V L G W+E + Y + S+ +W+ LP + + YY F+ FAI LNE++ + PTD+R RPDQ+ +EEG + A +EK R+EE QR +R +L K + Y P +F +++ + + N YWE + +S
Sbjct: 518 RRMHLPAPAADTSSIGLWDILRKNIGKDLSKVAMPVELNEPLNVLQRLCEEMEYSDLLDRAADTDDPAQRMVLVATFAVSTYASTISRAGGKPFNPVLGETYECIR-EDRGFRFIAEQVSHHPPISVCHCDSKKFVLWQDVRLKNKFWGKSMEIIPVGTVNVKLLKYGDEYEWNKVTSCIHNIMGGQRWIEHYGEVIIKNKKSNVCQCKINFIKASYWSSEA-NQVQGTVMDQNGRVLHRLFGKWNEGM----------------YCGAQRSARCIWRPGSLPQDHELYYGFTRFAIELNELDPVLRPHLPPTDTRFRPDQRFLEEGNMESAQREKLRIEEFQREKR----RLMEDKNIL--YTPRFFRKNITQDSREE-WLMNNTYWELRKDPGFS 889
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl1a (oxysterol binding protein-like 1A [Source:ZFIN;Acc:ZDB-GENE-050208-657]) HSP 1 Score: 212.231 bits (539), Expect = 5.915e-61 Identity = 155/428 (36.21%), Postives = 225/428 (52.57%), Query Frame = 3
Query: 1359 NMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES--NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYK-----------PYSMFSNDTPKRVTGAITDKLNNVCCVLN-GTWD----------EKLEAKNVISNTETVKGRTYLATEESSI----------------LLWQRYPLPPNFDKYYYFSSFAITLNEIEED----IAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
N ++WS ++ CIG +LSKI MPV F+EP+S LQRL E E++ ++ KA + + IE++ VAAF VS+ A+ R KPFNPLLGETYE+ R +D G+RL +EQ+ HHPP A E ++V KF GK ++ P G L R Y W +HN+IVG++WI+ +G ++I N K LS++ P S F D+ K+V+ I K V ++ G ++ EKL AK V + + G+ A E I LLW+ +P P N + Y F+SFA+TLNE+E++ +APTD R RPD K ME+G D A +EK RLEE+QR+ R + K T+E E+ WF +P + + + G Y++ + + C IF
Sbjct: 13 NFSIWSFLRRCIGMELSKITMPVIFNEPLSFLQRLCEYMEHTYLIHKANTSSSSIERMQCVAAFAVSAVASNWERTGKPFNPLLGETYEMVR-EDLGFRLVSEQVSHHPPISAFFAEGLNKDFVFHGSVYPKLKFWGKSVEAEPRGIITLELPRYGEAYTWTNPSCCVHNVIVGKLWIEQYGTVEITNHKRGFKASLSFRARNITKRKSRRPLSAFRIDSKKKVS-VIYGKWTEVLWSVDPGIYEVGKKNDKKSTEKL-AKLVAAESSGPSGQQAEADEADDIPTPEVPETVTVLPGSKLLWRVHPRPANSTQMYNFTSFALTLNEMEKEMEGLLAPTDCRLRPDMKAMEQGDIDLAGEEKNRLEEKQRAARKQRAK---TEE---EWHTRWFRQDLNPHTSTADWIYAGNYFD----RRYENCPNIF 427
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: osbpl6 (oxysterol binding protein-like 6 [Source:ZFIN;Acc:ZDB-GENE-070912-206]) HSP 1 Score: 127.872 bits (320), Expect = 2.703e-31 Identity = 80/165 (48.48%), Postives = 115/165 (69.70%), Query Frame = 3
Query: 1317 KRTRRTQIP-PKPNIN-MNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRI-NKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHL 1802
+ RR+ +P P P+ + ++LW++++N IGKDL+K+ MPV +EP++ LQRL E+ EYS +L++A+ ++P +++ AAF VS+YA T YR NKPFNP+LGETYE R +D G+R AEQ+ HHPP A HCES +V W D NKF GK ++I P+G L
Sbjct: 340 RNGRRSFLPAPCPDTSGVSLWNILRNNIGKDLAKVSMPVELNEPLNTLQRLCEELEYSELLEQASDTEDPAQRMVLAAAFAVSAYAPTYYRSGNKPFNPVLGETYECIR-EDKGFRFVAEQVSHHPPISACHCESKTFVLWQDVRWKNKFWGKSMEILPLGTVSL 503
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Match: OSBPL8 (oxysterol binding protein like 8 [Source:HGNC Symbol;Acc:HGNC:16396]) HSP 1 Score: 75.485 bits (184), Expect = 3.562e-14 Identity = 72/290 (24.83%), Postives = 130/290 (44.83%), Query Frame = 3
Query: 1218 ASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCI-GKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYE---LDRTDDFGWRLFAEQLCHHPPSCA--VHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSY--KPYSMFSNDTPKRVTGAITDKLNN-VCCVLNGTWDEKL 2060
A+ +N P +V Y F EV +T+ + N + +W+++K G DLSK+ +P EP S L +L++ + ++ IL +AA +N ++I V + +S + + KP+NP++GET+ + +EQ+ HHPP A + + + + +KF G + G+ L F Y+ I+ G + ++ G++ I T K + + KP+ + S+D+ +V+G I KL V L G WD ++
Sbjct: 293 AAVSNGSPPEPVVETGYVAELGEEFGEV-----GEAAQTETVSEENKGL-IWTLLKQLRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADILSQAAVEENAYDRIKQVVRWYLSGFYKKPKGLKKPYNPIIGETFRCMWIHPQTSSKTYYISEQVSHHPPISAFFISNRKDGFCISGNILARSKFYGNSLSAILDGEGKLTFLNRGEEYLMTMPYAHCKGILYGTMTLELGGKIIIDCEKTNYKAEIEFKLKPF-LGSSDSVNQVSGKI--KLGKEVLATLQGHWDREV 573
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH2 (Member of an oxysterol-binding protein family with seven members; in S. cerevisiae, family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane and at the nuclear envelope; regulated by sterol binding; OSH2 has a paralog, SWH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002177]) HSP 1 Score: 275.018 bits (702), Expect = 5.884e-78 Identity = 148/399 (37.09%), Postives = 228/399 (57.14%), Query Frame = 3
Query: 1362 MNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFK----RSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLAT--------EESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEED----IAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
++LW+V+K+ +GKD++++ +PV F+EP S+LQR+AED EYS +LD+AA+ ++ + YVAAFT SSYA+T R+ KPFNPLLGET+E R D +R F EQ+ HHPP A ES W W + + KF G+ + +G H+ + + Y W++ T+ I++G +DNHGE++++N TT D C L +K S+ +TG + +K +L G W+E + AK V+ + + +T A + + L+W+ P ++ + + FAITLN + + PTD+R RPDQ+ ME+G++DEA EK R+EE+QR+ R + +E EY P WF T P K+K +++ GKYW + D C IF
Sbjct: 896 ISLWAVLKSMVGKDMTRMTLPVTFNEPTSLLQRVAEDLEYSELLDQAATFEDSTLRTLYVAAFTASSYASTTKRVAKPFNPLLGETFEYSRPDK-QYRFFTEQVSHHPPISATWTESPRWDFWGESFVDTKFNGRSFNVKHLGLWHIKLRPNDNEKEELYTWKKPNNTVIGILIGNPQVDNHGEVNVVNHTTGDHCKLYFKARGWRSSGA-YEITGEVYNKKKQKVWILGGHWNEAIFAKKVVKDGDLSLEKTRTAASAGNGPTDDGTKFLIWKANDRP---EEPFNLTPFAITLNAPQPHLLPWLPPTDTRLRPDQRAMEDGRYDEAGDEKFRVEEKQRAARRK------REENNLEYHPQWFVRDTHPITKAKYWRYTGKYWVKRRDHDLKDCGDIF 1283 HSP 2 Score: 56.6102 bits (135), Expect = 1.689e-8 Identity = 31/87 (35.63%), Postives = 51/87 (58.62%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQ-NGLLSYYRNQSEMAQICRGTINIVNAKINLVDST-----SFVISHSGMQTFHLKSQNESEMKRW 356
KG+L KWTN+ GY+ RWF+L +G LSYY++QS + + RGT+ + +++ +DS+ + +G + LK + E RW
Sbjct: 293 KGFLKKWTNFAHGYKLRWFILSGDGNLSYYKDQSHVDR-PRGTLKVSTCRLH-IDSSEKLNFELLGGITGTTRWRLKGNHPIETTRW 377
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: SWH1 (Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats and FFAT motif; interacts with ER anchor Scs2p at the nucleus-vacuole junction; regulated by sterol binding; SWH1 has a paralog, OSH2, that arose from the whole genome duplication [Source:SGD;Acc:S000000081]) HSP 1 Score: 256.529 bits (654), Expect = 5.496e-72 Identity = 152/426 (35.68%), Postives = 237/426 (55.63%), Query Frame = 3
Query: 1305 PIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRS------KYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNV-----------ISNTETVKGRTYLATEESSILLW---QRYPLPPNFDKYYYFSSFAITLNEIEED----IAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
P+R+K PK + LWSV+K+ +G+DL+K+ +PV+F+EP S+LQR++ED EYS ILD+AA+ ++ ++ YVAAFT S YA+T R++KPFNPLLGET+E RTD +R F EQ+ HHPP A ES +W + + ++ + F G+ + +G ++ + + Y W++ T+ I++G+ +DN G++ + N TT D C L YK + +++ V G + +K + VL G W++ + K V I + G L + S L+W +R +P + +SFA+TLN + +APTDSR RPDQ+ ME G++D+A EK R+E +QR+ + E ++ EY+P WF P KS +KFNG+YW + D+ C IF
Sbjct: 783 PVRTKLALDEDNRPK----IGLWSVLKSMVGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLYVAAFTASMYASTTNRVSKPFNPLLGETFEYARTDG-QYRFFTEQVSHHPPISATWTESPKWDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEETYSWKKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHG-WTSAGAYEVRGEVFNKDDKKLWVLGGHWNDSIYGKKVTARGGELTLDRIKTANSATGGPKL--DGSKFLIWKANERPSVP------FNLTSFALTLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAAKKE------REQKGEEYRPKWFVQEEHPVTKSLYWKFNGEYWNKRKNHDFKDCADIF 1188 HSP 2 Score: 72.4034 bits (176), Expect = 2.190e-13 Identity = 37/104 (35.58%), Postives = 62/104 (59.62%), Query Frame = 3
Query: 60 QIIMETKNQNNVTLSSNIKGYLYKWTNYLKGYQKRWFVL-QNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSF----VISHSGMQTFHLKSQNESEMKRW 356
Q +++ N NN+ + KGYL KWTN+ +GY+ RWF+L +G LSYY +Q++ CRG++N+ + ++L S + ++G+ +HLK + E RW
Sbjct: 268 QSVIDVTN-NNLHEAPTYKGYLKKWTNFAQGYKLRWFILSSDGKLSYYIDQADTKNACRGSLNMSSCSLHLDSSEKLKFEIIGGNNGVIRWHLKGNHPIETNRW 370
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH3 (Member of an oxysterol-binding protein family; this family has seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; contains FFAT motif; interacts with ER anchor Scs2p at patches at the plasma membrane; regulated by sterol binding [Source:SGD;Acc:S000001115]) HSP 1 Score: 193.741 bits (491), Expect = 1.811e-51 Identity = 133/401 (33.17%), Postives = 199/401 (49.63%), Query Frame = 3
Query: 1323 TRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPK-RVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEE----DIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
TRR IP +L S ++ +GKDLS I MPV +EPIS+LQ ++E FEY+ +L KA +PI +S A +S Y + KPFNPLL ET+EL R +D G+RL +E++ H PP A E +W C + + S KF GK I+++ G L FK + + W + + N+I G +++ E + ++ + DK H+ + MFS + +V+ N L G W + LA E + +W+ L N K Y F+ F LNEI E ++ PTDSR RPD + EEG D+A + K +LE+ QR RR + + +P +F+ V+ E K T YWE + K DWS ++++
Sbjct: 628 TRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIR-EDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFE-VHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQS------------------LANETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERRNK----------GQDVEPKYFEKVSKNEWKYITGP--KSYWERRKKHDWSDISQLW 996
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH6 (Member of an oxysterol-binding protein family; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery; overexpression extends lifespan by promoting vacuolar fusion; OSH6 has a paralog, OSH7, that arose from the whole genome duplication [Source:SGD;Acc:S000001711]) HSP 1 Score: 70.0922 bits (170), Expect = 5.555e-13 Identity = 67/279 (24.01%), Postives = 119/279 (42.65%), Query Frame = 3
Query: 1353 NINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYEL--DRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSM--SNKFRGKYIQIHPIGKCHLLFKRSK------YHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPL 2159
NI +N+ S ++ G DL++I +P E SML+R+ ++ L +A S ++P+++ YV + ++ + + KP NP+LGE + D + +EQ HHPP CA E D + ++F G G L F K YV + + + I+ G++ I+ M I + + K Y + D + G + D N ++G W++ + K++ + K +L T + S L + PL
Sbjct: 49 NIILNIISQLRP--GCDLTRITLPTFILEKKSMLERVTNQLQFPEFLLQAHSEKDPLKRFLYVMKWYLAGWHIAPKAVKKPLNPVLGEYFTAYWDLPNKQQAYYISEQTSHHPPECAYFYMIPESSIRVDGVVIPKSRFLGNSSAAMMDGSTVLQFLDIKDGNGKPEKYVLTQPNVYVRGILFGKMRIELGDHMIIKSPNFQADIEFKTKGYVFGTYDA---IEGTVKDYDGNAYYEISGKWNDVMYLKDLKQPRSSPK--VFLDTHKESPLRPKVRPL 320
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Match: OSH7 (Oxysterol-binding protein; part of family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability; OSH7 has a paralog, OSH6, that arose from the whole genome duplication [Source:SGD;Acc:S000001043]) HSP 1 Score: 58.5362 bits (140), Expect = 2.431e-9 Identity = 36/117 (30.77%), Postives = 61/117 (52.14%), Query Frame = 3
Query: 1353 NINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYEL--DRTDDFGWRLFAEQLCHHPPSCA 1697
+I +N+ S +K G DLS+I +P E SML+R+ ++ +L +A S ++ +++ V A+ ++ + + KP NP+LGE + D + AEQ HHPP A
Sbjct: 49 SILLNIISQLKP--GCDLSRITLPTFILEKKSMLERITNQLQFPDVLLEAHSNKDGLQRFVKVVAWYLAGWHIGPRAVKKPLNPILGEHFTAYWDLPNKQQAFYIAEQTSHHPPESA 163
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO44125 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7RWH9]) HSP 1 Score: 458.759 bits (1179), Expect = 1.070e-149 Identity = 215/410 (52.44%), Postives = 283/410 (69.02%), Query Frame = 3
Query: 1320 RTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVI---SNTETVKGRTYLATEESS---ILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRR-------VEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+T RT IPP+P+I++NLWS++KNCIGK+L+KIPMPVNF+EP+SMLQR+ E+ EYS +LDKAA+C + +EQ+ YVAAFTVSSY+ T+ R NKPFNPLLGET+E DR++D+GWR AEQ+ HHPP+ A H E +W+ W +FS ++KFRGKY+QI P G HL F +S HY W ++ T+HNIIVG++WID GEMDI N TT + CHL Y Y+ F DTP++VTG +TD V V++GTWD K+EA V+ S +G + + + ++LW+R PP +K Y +SFAITLNE E+ +APTDSR RPDQ+LME W+EAN+EK R+E+QQR+RR E L DG F Y P WF+ + D + + G YWE K KKDW C IF
Sbjct: 324 KTYRTSIPPRPDISINLWSILKNCIGKELTKIPMPVNFNEPLSMLQRITEELEYSEVLDKAAACTSSLEQMCYVAAFTVSSYSTTSNRTNKPFNPLLGETFECDRSEDYGWRSLAEQVSHHPPASAFHAEHKDWIFWQEFSATSKFRGKYLQIIPQGIAHLKFIKSGNHYTWRKVTTTVHNIIVGKLWIDQSGEMDIANHTTNENCHLKYDAYNYFGRDTPRKVTGVVTDSTKTVRYVISGTWDNKIEAAKVVYLKSPGVKAQGSSSQKGQPQTLPPVVLWKRVLPPPENEKMYAMTSFAITLNEPEDHVAPTDSRFRPDQRLMENCHWEEANQEKLRIEDQQRTRRRKREQEAAEALS-DGI--FYEGYSPSWFEKIVDELTDMPMHVYKGGYWEAKEKKDWGSCPDIF 730 HSP 2 Score: 176.792 bits (447), Expect = 4.047e-46 Identity = 94/229 (41.05%), Postives = 147/229 (64.19%), Query Frame = 3
Query: 108 NIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLE 794
+ +G+L KWTNY+KGYQ+RWFVL NGLLSYYRNQ+EMA CRGTIN+ A I+ D+ SFVIS+ G Q FHL++ E E +RW +AL A+ KA +L+ + + D E + L+ L D++ D++ + LQ++I +L + ++++ + KLK + E+AT+FR+++ +++++CA + E + +KW+K + ER QR +E VE L +QH LE
Sbjct: 10 HFRGWLLKWTNYIKGYQRRWFVLSNGLLSYYRNQAEMAHTCRGTINLAGAFIDTEDACSFVISNGGTQVFHLRASTEVERQRWVTALELAKAKAIKMLESDEEEEGASDHAENIK----PLSSKLSDLQTCNDLVGKHGSALQRAIGELQEIEDNHTLFN---KLKAVNEKATLFRITSNAMISACAEFLELAQAQEKKWQKSLQYERNQRINLEETVEVLGRQHYLLE 231
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO41441 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7S4A2]) HSP 1 Score: 288.115 bits (736), Expect = 1.049e-88 Identity = 154/387 (39.79%), Postives = 229/387 (59.17%), Query Frame = 3
Query: 1317 KRTRRTQIPP---KPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIA-PTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYW 2465
+R RRT +P + +I +L S +K +GKD++K+ MPV+F+EP+S LQRL+ED EY+ IL++A C+N + ++++VAAF S+YA R KPFNPLLGET+E D+ G+ L AEQ+ HHPP A+H ES+ WV W ++ + KFRG++ ++ P G CHL FK + +H+ W++ TIHNI+VG +++D G+M + N TT++ C + + P D K++ G + D V V+ G+WD+ LE + +T + SI LW P + K Y F+ F I LN+ + + PTD RNRPD + +E GK D + EK RLEE+QR+ R E Y+ K WF P DP ++ Y + G YW
Sbjct: 37 RRPRRTALPATRERSSIR-SLISFMKTVVGKDMTKVTMPVHFNEPVSFLQRLSEDLEYADILNRACVCKNNLVKLAHVAAFASSTYATVLSRFWKPFNPLLGETFEYIDNDN-GFALIAEQVSHHPPISALHAESSHWVFWQEYKLDTKFRGQFFKVIPTGHCHLKFKTNGHHFSWKKPVTTIHNILVGSLYVDQEGDMVVTNHTTKETCTVHFMPVRKV-QDNFKKLKGEVKDPEGKVRYVIEGSWDKSLEC--IPQDT---------GFNDDSIDLWTAVARPDDSYKMYAFTRFTIQLNDPDYGVTCPTDCRNRPDIRQLELGKIDSSAAEKHRLEEKQRASRRERDTKGEAWTPRYDKKDRWFVPKEDPYTRTFDYVYRGGYW 409
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO39767 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7S940]) HSP 1 Score: 239.58 bits (610), Expect = 3.666e-71 Identity = 139/401 (34.66%), Postives = 211/401 (52.62%), Query Frame = 3
Query: 1362 MNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKL---EAKNVISNTETVKGR-----------TYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEI----EEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
++W+V+K CIGKDLS+I MPV F+EP++ LQR+ E EYS +L AAS +P ++ ++ KPFNPLLGETYEL R G+RL AEQ+ HHPP A+ CES++++ KF GK +++ P G L F + Y W + +HNIIVG++WI+ +G+++I +L++ D+ + +KP F + K + L G W +K+ ++ ++ ++ +G+ S + LW PP+ + Y F+SFA+ LNE+ +E + PTDSR RPD + +E G D A EK RLEE+QR+ R E K D E+ P WF +P + ++G YW+ +DW C IF
Sbjct: 7 FSVWTVLKQCIGKDLSRITMPVIFNEPLTFLQRITEYMEYSELLHTAASQDDPTRRL----------------QVGKPFNPLLGETYELVRP---GFRLVAEQVSHHPPITALQCESDDFIFHVTVQPKLKFWGKGVEVQPKGMVTLKFPKHNEVYTWNNVNSCVHNIIVGQLWIEQYGQIEISSLSSGDRATIHFKPAGWFGKELNKVEATIHCAQDKKKRYTLKGDWTDKITCYRSETHVTRKQSKRGKQDFEIASTSSSETSLELHSPVTLWTCSHRPPHSKEMYNFTSFAMQLNELLPRDKETLPPTDSRLRPDCRALENGDLDRATAEKIRLEEKQRAARRERQKSD------QEWAPRWFKEEMNPYTGQMDWLYSGGYWD----RDWQECPDIF 378
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO28432 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6H1]) HSP 1 Score: 74.7146 bits (182), Expect = 3.223e-16 Identity = 46/114 (40.35%), Postives = 62/114 (54.39%), Query Frame = 3
Query: 2181 YYFSSFAITLNEI----EEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
Y F+SFA+ LNE+ +E + PTDSR RPD + +E G D A EK RLEE+QR+ R E K D E+ P WF +P + ++G YW+ +DW C IF
Sbjct: 2 YNFTSFAMQLNELLPRDKETLPPTDSRLRPDCRALENGDLDRATAEKIRLEEKQRAARRERQKSD------QEWAPRWFKEEMNPYTGQMDWLYSGGYWD----RDWQECPDIF 105
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Match: EDO47800 (Oxysterol-binding protein [Source:UniProtKB/TrEMBL;Acc:A7RL46]) HSP 1 Score: 78.9518 bits (193), Expect = 2.228e-15 Identity = 74/282 (26.24%), Postives = 123/282 (43.62%), Query Frame = 3
Query: 1353 NINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSY--AATAYRINKPFNPLLGETYE------------LDRT------------DDFGWRLFAEQLCHHPPSCAVHCES-NEWVCW-FDFSMSNKFRGKYIQIHPIGKC--HLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSY--KPYSMFSNDTPKRVTGAITD-KLNNVCCVLNGTWDEKLEAKNVISNTETVK 2099
++ ++L S +K +G DL+K+ +P EP S+L+ A+ F + + + A ++I V F ++S+ KP+NP+LGET+ ++R DD G R AEQ+ HHPP + E + +C +KF G I + +G+ LL +YH+ + P I+ W++ G++ I T +++ KP F RVTG + + V C + G W+ K+E N SN E K
Sbjct: 79 SVILHLLSQLK--LGMDLTKVVLPTFILEPRSLLEMYADFFAHPDMFIRIADGLTAEDRILAVLEFYLTSFHVGRKGSLAKKPYNPILGETFTCSWDVREECSTGMERNPLNLANDVSVMEDDRGLRFVAEQISHHPPVSGFYAECPRKKICLNAHIWTKSKFYGMSIGVANVGEAVITLLEHEEEYHFTF---PSAFCRSILTFPWVELGGKLHITCPKTGYNASVTFHTKP---FYGGKLHRVTGEVKNASTGKVICKVAGEWNGKIEF-NYTSNQEQAK 351
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: osbp2 (oxysterol-binding protein 2 [Source:NCBI gene;Acc:101170773]) HSP 1 Score: 454.907 bits (1169), Expect = 1.275e-147 Identity = 221/464 (47.63%), Postives = 303/464 (65.30%), Query Frame = 3
Query: 1212 ITASSNNMHKPI--NLVSLTYNTSNIATFSEVIP--IRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVI-----SNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVE-------------------ILK--LDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+TA+S+ HK + + + T+ S F + ++ +RTRRT+IP KPN ++NLWS++KNCIGKDLS+IPMPVNF+EP+SMLQRL ED EYS +LD+AA C + +EQ+ VAAF+VSSY+ T +R KPFNPLLGETYELDR ++G+R +EQ+ HHPP+ A H S W W ++ +KFRGKYI + P+G HL F S HYVW ++ T+HNIIVG++WID G++DI+N TT+D C L + PYS FS + P++VTG + D+ +L+GTWD+K+E+ ++ K +T T + LLW++YPLP N + ++FSS A+TLNE EE +APTDSR RPDQ+LMEEG WDEAN +K RLEE+QR R + LK + T + + Y+PLWFD TD TY + G YWE K +++WS C +IF
Sbjct: 293 VTAASDIQHKQLASQVSAFTFTESLFVCFKDTSTNHMQLRRTRRTRIPDKPNYSLNLWSIMKNCIGKDLSRIPMPVNFNEPLSMLQRLTEDLEYSELLDRAARCDSSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRL-EYGYRSISEQISHHPPAAAHHVTSQRGWTLWQHITIDSKFRGKYISVVPLGNIHLQFHSSGNHYVWSKVTSTVHNIIVGKLWIDQSGDIDIVNTTTKDTCRLKFSPYSYFSREVPRKVTGVVEDREGTAHYILSGTWDDKMESAKIVESSHGGGGSEGKQKTVYQTLQPK-LLWKKYPLPENAENMHFFSSLALTLNEPEEGVAPTDSRLRPDQRLMEEGLWDEANIQKQRLEERQRQERKKREAQANQALEDGEFMDCQIFLKNYMCSTGQDIEGYQPLWFDRKTDENTGDATYFYKGGYWEAKERQNWSQCPRIF 754 HSP 2 Score: 182.185 bits (461), Expect = 2.121e-47 Identity = 103/280 (36.79%), Postives = 162/280 (57.86%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSEL----DSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPS 941
KG+L+KWTNYLKGYQ+RWFVL NGLLSYYR Q+EMA CRGTI + A I + D+ V++ SG +++HLK+ +E+E +RW SAL A+ A L+ D++ E + L G + L L+D+ +++ + LQ+S+ +L++ + SN + K+K + ERAT+FR+++ ++L +C + + + +W+K + EREQR +E +E LAKQH LE + +N Q+ +D + +F+DA E VT S
Sbjct: 25 KGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTIPLATAHIGVGDACHLVLT-SGGRSYHLKATSEAECQRWVSALQQAKDNATVLMHHSDDSGDEAPIPHEERALTQGVLKTLASKLDDLSTCNELIGKHGAALQRSLSELEELRGSN---DNTDKVKAVNERATLFRITSNAMLNACRDFLDVAESHSRRWQKALHYEREQRHHLEETIEQLAKQHNSLE---RAWRENPSSYAGRRPQDGDVSDDNEEAEFFDAMEDSTAFITVTAAS 297
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: si:ch211-106a19.1 (oxysterol-binding protein 2 [Source:NCBI gene;Acc:101175572]) HSP 1 Score: 442.58 bits (1137), Expect = 9.676e-145 Identity = 208/404 (51.49%), Postives = 278/404 (68.81%), Query Frame = 3
Query: 1326 RRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS-----NTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRS--RRVEILKLDGTKEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
RRT++P KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LDKAA C++ +EQ+ VAAF+VSSY+ T +R KPFNPLLGETYELDR ++FG+R EQ+ HHPP+ A H S W W + ++++KFRGKY+ I P+G HL F S HYVW ++ T+HNIIVG++WID G+++I+N T++ C L + PYS FS D P++VTG + D +L+GTWD+K+E+ ++ + K +T T S LLW++YPLP N + YYFSS A+TLNE EE +A TDSR RPDQ+LME+G+WDEAN EK RLEE+QR+ RR E YE Y+PLWF D ++ + G YWE K +DW++C IF
Sbjct: 203 RRTRVPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCESSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVISQRGWTLWQEITIASKFRGKYLSIMPLGTIHLQFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIVNHRTKEACQLKFSPYSYFSRDVPRKVTGVVADSSGQAHYILSGTWDDKMESAKILQSSRGGSGSEGKQKTVYQT-LSPKLLWKKYPLPENAENMYYFSSLALTLNEPEEGVAVTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRAVRRRREGCPGPLCCASEYEGYQPLWFHQRRDSLTGETSFVYKGGYWETKESQDWNICPDIF 605 HSP 2 Score: 82.8037 bits (203), Expect = 6.459e-16 Identity = 55/182 (30.22%), Postives = 96/182 (52.75%), Query Frame = 3
Query: 405 GCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQ------ISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVT 932
G + S+ D +EL G + L L+D+ D++ + LQ+S+ +L+ K + GE K+K + ERAT+FR+++ +++ +C + + + +W++ + EREQR +E +E LAKQH LE ++SS + N EP++DED D +++DA E VT
Sbjct: 8 GDEEPTSQSDRSEL-QGTLKLLVSKLDDLSTCNDLIAKHGAALQRSLTELEGLKVTIEGGE---KIKAVNERATLFRITSNAMINACRDFLDLAETHSRRWQRALQYEREQRTHLEETIEQLAKQHNSLERAWREAPTLASSSPSAPTTN---KGEPASDED-EDTEYFDAMEDSPAFITVT 181
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: si:ch211-106a19.1 (oxysterol-binding protein 2 [Source:NCBI gene;Acc:101175572]) HSP 1 Score: 445.277 bits (1144), Expect = 2.539e-144 Identity = 213/441 (48.30%), Postives = 294/441 (66.67%), Query Frame = 3
Query: 1212 ITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS-----NTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKL--DGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+TAS ++ H+ ++ + N + E+ P +R RRT++P KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LDKAA C++ +EQ+ VAAF+VSSY+ T +R KPFNPLLGETYELDR ++FG+R EQ+ HHPP+ A H S W W + ++++KFRGKY+ I P+G HL F S HYVW ++ T+HNIIVG++WID G+++I+N T++ C L + PYS FS D P++VTG + D +L+GTWD+K+E+ ++ + K +T T S LLW++YPLP N + YYFSS A+TLNE EE +A TDSR RPDQ+LME+G+WDEAN EK RLEE+QR+ R + E Y+PLWF D ++ + G YWE K +DW++C IF
Sbjct: 288 VTASESSQHRSMS------PSCNDVSGKELQP---RRERRTRVPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCESSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVISQRGWTLWQEITIASKFRGKYLSIMPLGTIHLQFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIVNHRTKEACQLKFSPYSYFSRDVPRKVTGVVADSSGQAHYILSGTWDDKMESAKILQSSRGGSGSEGKQKTVYQT-LSPKLLWKKYPLPENAENMYYFSSLALTLNEPEEGVAVTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRAVRRRREAEASEALDEEYEGYQPLWFHQRRDSLTGETSFVYKGGYWETKESQDWNICPDIF 718 HSP 2 Score: 184.111 bits (466), Expect = 3.583e-48 Identity = 111/286 (38.81%), Postives = 170/286 (59.44%), Query Frame = 3
Query: 102 SSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXX---XXGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQ------ISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVT 932
S KG+L+KWTNYLKGYQ+RWFVL NGLLSYYR Q+EMA CRGTIN+ A I+ D+ + V+S SG +T+HLK+ E E +RW +AL A+ KA + G + S+ D +EL G + L L+D+ D++ + LQ+S+ +L+ K + GE K+K + ERAT+FR+++ +++ +C + + + +W++ + EREQR +E +E LAKQH LE ++SS ++ N+E ++DED D +++DA E VT
Sbjct: 15 SDTYKGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLATAHIDTEDACNIVLS-SGGRTYHLKASTEVERQRWVTALELAKAKAIRMMNDQSGDEEPTSQSDRSEL-QGTLKLLVSKLDDLSTCNDLIAKHGAALQRSLTELEGLKVTIEGGE---KIKAVNERATLFRITSNAMINACRDFLDLAETHSRRWQRALQYEREQRTHLEETIEQLAKQHNSLERAWREAPTLASSSPSE-----RSNKEEASDED-EDTEYFDAMEDSPAFITVT 289
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: si:ch211-106a19.1 (oxysterol-binding protein 2 [Source:NCBI gene;Acc:101175572]) HSP 1 Score: 441.039 bits (1133), Expect = 2.197e-142 Identity = 217/451 (48.12%), Postives = 297/451 (65.85%), Query Frame = 3
Query: 1212 ITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVIS-----NTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV-------EILKLDGT----KEFVYE-YKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
+TAS ++ H+ ++ + N + E+ P +R RRT++P KPN ++NLWS++KNCIGK+LSKIPMPVNF+EP+SMLQRL ED EY +LDKAA C++ +EQ+ VAAF+VSSY+ T +R KPFNPLLGETYELDR ++FG+R EQ+ HHPP+ A H S W W + ++++KFRGKY+ I P+G HL F S HYVW ++ T+HNIIVG++WID G+++I+N T++ C L + PYS FS D P++VTG + D +L+GTWD+K+E+ ++ + K +T T S LLW++YPLP N + YYFSS A+TLNE EE +A TDSR RPDQ+LME+G+WDEAN EK RLEE+QR+ R E L T YE Y+PLWF D ++ + G YWE K +DW++C IF
Sbjct: 299 VTASESSQHRSMS------PSCNDVSGKELQP---RRERRTRVPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDKAARCESSLEQMCLVAAFSVSSYSTTVHRTAKPFNPLLGETYELDRLEEFGYRSLCEQVSHHPPAAAHHVISQRGWTLWQEITIASKFRGKYLSIMPLGTIHLQFHSSGNHYVWRKVTSTVHNIIVGKLWIDQSGDIEIVNHRTKEACQLKFSPYSYFSRDVPRKVTGVVADSSGQAHYILSGTWDDKMESAKILQSSRGGSGSEGKQKTVYQT-LSPKLLWKKYPLPENAENMYYFSSLALTLNEPEEGVAVTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRAVRRRREAEASEALDEGNTCASSAGREYEGYQPLWFHQRRDSLTGETSFVYKGGYWETKESQDWNICPDIF 739 HSP 2 Score: 184.111 bits (466), Expect = 3.943e-48 Identity = 112/287 (39.02%), Postives = 167/287 (58.19%), Query Frame = 3
Query: 102 SSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXX---XXGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQ-------ISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVT 932
S KG+L+KWTNYLKGYQ+RWFVL NGLLSYYR Q+EMA CRGTIN+ A I+ D+ + V+S SG +T+HLK+ E E +RW +AL A+ KA + G + S+ D +EL G + L L+D+ D++ + LQ+S+ +L+ K + GE K+K + ERAT+FR+++ +++ +C + + + +W++ + EREQR +E +E LAKQH LE SSS N+E ++DED D +++DA E VT
Sbjct: 20 SDTYKGWLFKWTNYLKGYQRRWFVLSNGLLSYYRTQAEMAHTCRGTINLATAHIDTEDACNIVLS-SGGRTYHLKASTEVERQRWVTALELAKAKAIRMMNDQSGDEEPTSQSDRSEL-QGTLKLLVSKLDDLSTCNDLIAKHGAALQRSLTELEGLKVTIEGGE---KIKAVNERATLFRITSNAMINACRDFLDLAETHSRRWQRALQYEREQRTHLEETIEQLAKQHNSLERAWREAPTLASSSPSAPTTNKGESNKEEASDED-EDTEYFDAMEDSPAFITVT 300
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Match: ENSORLT00000007524.2 (oxysterol-binding protein 1 [Source:NCBI gene;Acc:101155887]) HSP 1 Score: 412.149 bits (1058), Expect = 5.379e-131 Identity = 207/416 (49.76%), Postives = 278/416 (66.83%), Query Frame = 3
Query: 1293 SEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNE-WVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTE----TVKGRTYLATEE-SSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRS----RRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
SE++P++ +RTR IP KPN ++NLWS++KNCIGK+LSKIPMPVNF+EPISMLQRL+ED EY +LDKAA N +EQ+ YVAAF VS+Y+ T YR KPFNPLLGETYELDR + G+R EQ+ HHPP+ A H S+ W + ++++KFRGKY+ I P+G H +F++S HY W+++ T+HNIIVG++WID GE+D++N TT D+CHL + PYS FS D ++VTG + DK VL+GTWDEK+E V+ ++ +GR + + LW+R PLP + YYF++ A+TLNE E+ +APTDSR RPDQ+LME+G+WDEAN EK RLEE+QR+ R E L + YK WF+ D + + G YWE K + W C IF
Sbjct: 351 SELVPLKKRRTR---IPDKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPISMLQRLSEDLEYHELLDKAAKSHNSLEQMCYVAAFCVSAYSTTVYRTGKPFNPLLGETYELDRQRESGYRSLCEQVSHHPPAAAHHAISDRGWTLRQEITVASKFRGKYLSIMPLGTIHAIFEKSNNHYTWKKVTTTVHNIIVGKLWIDQSGEIDVVNHTTGDRCHLKFAPYSYFSRDVARKVTGVVMDKTGKAHYVLSGTWDEKMEFSRVMQSSRGGENGTEGRQKTVYQTLKAKELWRRNPLPDGAETMYYFTALALTLNEPEDGVAPTDSRLRPDQRLMEDGRWDEANAEKQRLEEKQRTARREREREALNQRSSSVPHENYKARWFEHTEDKITGEAVHVYKGGYWEAKDQGKWDDCPDIF 763 HSP 2 Score: 193.356 bits (490), Expect = 4.307e-51 Identity = 106/290 (36.55%), Postives = 166/290 (57.24%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSEL-----------DSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDED---FYDAFESQEGVFNVTLPS 941
KG+++KWTNY+KGYQ+RWFVL NGLLSYYR Q+EM CRGTIN+ A I + D+ +F+I++ G QT+HLK+ E E ++W +AL A+ KA + D++ + N + L +ED+ D++ + LQ+S+ +LD N + GE K++ + ERAT+FR+++ +++ +C + +++W+K + +EREQR R+E +E LAKQH HLE + Q + P E VSD+D F+DA E E +T+P+
Sbjct: 43 KGWVFKWTNYIKGYQRRWFVLSNGLLSYYRTQAEMGHTCRGTINLATATITVDDACNFMITNGGAQTYHLKASCEVERQKWITALELAKAKAARMQAESDDSGDDFSPSAAPGQGAGSQNAEFQSAMRMLGSKVEDLSTCNDLISKHGSALQRSLSELD---NLTLTGEAGEKIRQVTERATLFRITSNAMINACRDFLSMAQTHSKRWQKALQAEREQRVRLEETLEQLAKQHNHLERAFRGAAQANASADSKSISGPGKGE-VSDDDDNEFFDAME--EAPEFITVPA 326
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000008795.1 (SMESG000008795.1) HSP 1 Score: 1620.14 bits (4194), Expect = 0.000e+0 Identity = 818/821 (99.63%), Postives = 821/821 (100.00%), Query Frame = 3
Query: 69 METKNQNNVTLSSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPSPEINLGVSLPSRCXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFFIGDSSTRGFEEVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIFDNQNHTV 2531
METKNQNNVTLSSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSALLAAQKKAQDLLKGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPSPEINLGVSLPSRCSELSLEYESDVEDELSDLSDNDSGLNCSRN+TDNFFIGDSSTRGFEEVSNKRSLQRLKEARVISAKQ+NQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETV+GRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIFDNQNHTV
Sbjct: 1 METKNQNNVTLSSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSALLAAQKKAQDLLKGCDNNDSELDSNELVNGFILKLNGHLEDIKKSQDVLYRKLDDLQKSIHDLDKDKNSNIVGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQISSSVQNQLKLNINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPSPEINLGVSLPSRCSELSLEYESDVEDELSDLSDNDSGLNCSRNHTDNFFIGDSSTRGFEEVSNKRSLQRLKEARVISAKQNNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVQGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIFDNQNHTV 821
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000023068.1 (SMESG000023068.1) HSP 1 Score: 613.994 bits (1582), Expect = 0.000e+0 Identity = 368/892 (41.26%), Postives = 496/892 (55.61%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRW-TSXXXXXXXXXXXXXXGCDNNDSE--LDSNELVNGF-----------------------------------ILKLNGHLEDIKKSQDVLYRKLDDLQK-------SIHDLDKDKNSNI---------------------------VGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQI---SSSVQNQLKL--------NINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPSPEINLGVSLPSR--------CXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFF--IGDSSTRGFEEVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRR------VEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDW 2489
KGYLYKWTNY+KGYQKRWFVL NGLLSYYRN++E++ CRGTIN+ + I DS S VIS+ QTFHLK+Q+ESE +W T+ LA D++DSE L S L N + LN + +KK+ + L L D+ K S + ++ D + ++ +G + + KE+ F V+ + + SC+ +A T K++K++++EREQR R+E MVE+LAKQ LE + S SV L N+ A +D DE FYDA E E VFNV+LP P V L + CS S + + + S N S++ N IGDSS VS+ Q L + + A + NQ N K + N+ ++ S ++ + S + + R RRT+I P+PN+++NLW ++KNCIGK+LSKIP+PVNF+EP+SM+QRL EDFEYS LD AA C + +EQ+S+VAAFTVSSY+ T R KPFNPLLGET+E DRTDD GWR AEQ+ HHPP+ ++HCES W CW +F+MS+KFRGKY+ I P+G HL F++S HY W ++ T+HNIIVG++WIDNHGEMDI N T + CHL+YK YS FS + +RVTG ITDK VLNGTWD + V+ + + T + L +R+P P + Y F++FA+ LNE EE++APTDSR RPDQ+LME G WDEANKEK RLEE+QR +R +E K G + E+KP+WF PV D E K+ T+ ++G YWE KA W
Sbjct: 10 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEAVLDDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESLLNVLKDVNKLNSPHIISNYSINSDSSVDMKAHDQSSLNSHSSVLLNIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIE-DEHVFNVSLPRPISQNNVKLEPKYTINEYESCSSDSEYEKDNSKGNSIARVIVRSTENKSKSNHKNKINNIGDSSQFHRRTVSSGFPSQSLCPSNSLKANK-NQCDNLGKDLY----NVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFP-PEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEANKEKERLEEKQREKRRNREKEIEQRKSQGLPP-IEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 893
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000023068.1 (SMESG000023068.1) HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0 Identity = 370/891 (41.53%), Postives = 500/891 (56.12%), Query Frame = 3
Query: 114 KGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMAQICRGTINIVNAKINLVDSTSFVISHSGMQTFHLKSQNESEMKRWTSXXXXXXXXXXXXXXGCDNNDSE--LDSNELVNGF-----------------------------------ILKLNGHLEDIKKSQDVLYRKLDDLQK-------SIHDLDKDKNSNI---------------------------VGEIALKLKNIKERATIFRVSAASILTSCAAYAESVTGEAEKWRKVIDSEREQRQRMENMVEDLAKQHRHLEYQI---SSSVQNQLKL--------NINPNQEPSADEDVSDEDFYDAFESQEGVFNVTLPSPEINLGVSLPSR--------CXXXXXXXXXXXXXXXXXXXXXXXXXNCSRNYTDNFF--IGDSSTRGFEEVSNKRSLQRLKEARVISAKQSNQLKNRQKLITASSNNMHKPINLVSLTYNTSNIATFSEVIPIRSKRTRRTQIPPKPNINMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCES-NEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRR------VEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDW 2489
KGYLYKWTNY+KGYQKRWFVL NGLLSYYRN++E++ CRGTIN+ + I DS S VIS+ QTFHLK+Q+ESE +W +AL A+ A L + D++DSE L S L N + LN + +KK+ + L L D+ K S + ++ D + ++ +G + + KE+ F V+ + + SC+ +A T K++K++++EREQR R+E MVE+LAKQ LE + S SV L N+ A +D DE FYDA E E VFNV+LP P V L + CS S + + + S N S++ N IGDSS VS+ Q L + + A + NQ N K + N+ ++ S ++ + S + + R RRT+I P+PN+++NLW ++KNCIGK+LSKIP+PVNF+EP+SM+QRL EDFEYS LD AA C + +EQ+S+VAAFTVSSY+ T R KPFNPLLGET+E DRTDD GWR AEQ+ HHPP+ ++HCES W CW +F+MS+KFRGKY+ I P+G HL F++S HY W ++ T+HNIIVG++WIDNHGEMDI N T + CHL+YK YS FS + +RVTG ITDK VLNGTWD + V+ + + T + L +R+P P + Y F++FA+ LNE EE++APTDSR RPDQ+LME G WDEANKEK RLEE+QR +R +E K G + E+KP+WF PV D E K+ T+ ++G YWE KA W
Sbjct: 10 KGYLYKWTNYIKGYQKRWFVLSNGLLSYYRNKNEVSHTCRGTINLSTSIIRKQDSFSIVISNDSNQTFHLKAQSESETNQWLTALHLAKDTAISLSEA-DDSDSEAPLGSPYLGNSLTKPHHSHSQNILPIDRLHSSDASDISLYYKEFEQRLFDLNTSVSLVKKTSESLLNVLKDVNKLNSPHIISNYSINSDSSVDMKAHDQSSLNSHSSVLLNIDHRAPSHSSIGPVPDLMHKFKEKNKTFFVATQACVNSCSEFANRATCIFSKYQKLLNTEREQRLRLEKMVEELAKQLGALEKKAVKQSESVGLNTSLPQHSDDEKNVRVKNTDQASDDSDDEYFYDAIE-DEHVFNVSLPRPISQNNVKLEPKYTINEYESCSSDSEYEKDNSKGNSIARVIVRSTENKSKSNHKNKINNIGDSSQFHRRTVSSGFPSQSLCPSNSLKANK-NQCDNLGKDLY----NVSGDVSTFSELKTAQSVPSLSTKVEKKPARVRRTKITPRPNMSINLWGIMKNCIGKELSKIPVPVNFNEPLSMIQRLTEDFEYSDCLDAAAECADSLEQLSWVAAFTVSSYSTTTNRTGKPFNPLLGETFEFDRTDDLGWRSLAEQVSHHPPAASLHCESIKGWKCWQEFTMSSKFRGKYLAIIPMGIAHLTFEKSNNHYTWRKVTSTVHNIIVGKLWIDNHGEMDIYNHKTGETCHLNYKAYSYFSKEPARRVTGVITDKDGVTKYVLNGTWDSHFQRAKVLHIRKDKNNQQVFETGPAETLWSRRFP-PEYTSEMYNFTNFALELNEPEENVAPTDSRLRPDQRLMETGFWDEANKEKERLEEKQREKRRNREKEIEQRKSQGLPP-IEEHKPVWFAPVFDEETKTTTHIYSGNYWETKATGAW 891
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000065901.1 (SMESG000065901.1) HSP 1 Score: 235.343 bits (599), Expect = 2.523e-68 Identity = 157/455 (34.51%), Postives = 228/455 (50.11%), Query Frame = 3
Query: 1323 TRRTQIP-PKPN-INMNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRINKPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDIINLTTEDKCHLSYKPYSMFSNDTPKRVTGAI---TDKLNNVCCVLNGTWDEKL-------------EAKNVISNTETV----KGRTYLATEESSI---------------LLWQRYPLPPNFDKYYYFSSFAITLNEIEE----DIAPTDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRV------------------EILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECKAKKDWSMCNKIF 2510
T RT +P P P+ +N ++W+ +K CIGK+LSKI MP+ F+EPIS LQRL E EYS +LD+A + +PI+++ + AF VS A+ RI KPFNPLLGETYEL R + ++ +EQ+CHHPP A H ES + + F GK + I P G L Y W+ + T+HN+I+G++WI++ G M IIN + L++ F + RV G I K +V + G W E L +K +++T+ + KG + + L+W+ P P N +Y F+SF + LN+I + ++ PTDSR R D + MEEG DEA K LEE+QR++RV EI + KE P+WF + ++F G+YW +DWS+C IF
Sbjct: 26 TYRTGLPKPMPSKLNFSVWTFLKQCIGKELSKITMPIVFNEPISFLQRLTEYIEYSELLDQAVAEIDPIKRMEKICAFAVSGGASNWGRIGKPFNPLLGETYELHRPN---FKYVSEQICHHPPVSAFHVESPTFKFYGAIHPKLNFWGKSVVITPKGNITLELLPWNEVYTWQNVVCTVHNVIIGKIWIEHSGPMRIINHSNNCIADLTFHSVGWFGKNM-HRVDGDIYYGQRKSRHVERKVYGKWTEALFSVSPEVWNDDSSTSKRHVNSTDQIENDEKGDNNNNDIDDPLPQDNTPCDMKLLNQRLIWKAKPRPDNSAIFYNFTSFTMGLNQITDSFSRELPPTDSRFRQDMRYMEEGLLDEAANAKNYLEEKQRAKRVALKSSNSKKNMNKSSSSHEITDIRNQKE-----GPVWFAEKLNSYTNKMEWQFTGEYW----NRDWSVCPDIF 467
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Match: SMESG000046022.1 (SMESG000046022.1) HSP 1 Score: 233.417 bits (594), Expect = 2.421e-64 Identity = 144/396 (36.36%), Postives = 220/396 (55.56%), Query Frame = 3
Query: 1311 RSKRTRRTQIPP-KPNIN-MNLWSVVKNCIGKDLSKIPMPVNFSEPISMLQRLAEDFEYSSILDKAASCQNPIEQISYVAAFTVSSYAATAYRIN-KPFNPLLGETYELDRTDDFGWRLFAEQLCHHPPSCAVHCESNEWVCWFDFSMSNKFRGKYIQIHPIGKCHLLFKRSKYHYVWERIPMTIHNIIVGRVWIDNHGEMDII-NLTTEDKCHLSYKPYSMFSNDTPKRVTGAITDKLNNVCCVLNGTWDEKLEAKNVISNTETVKGRTYLATEESSILLWQRYPLPPNFDKYYYFSSFAITLNEIEEDIAP----TDSRNRPDQKLMEEGKWDEANKEKARLEEQQRSRRVEILKLDGTKEFVYEYKPLWFDPVTDPEAKSKTYKFNGKYWECK 2474
+ K RR ++P +P+I+ +L +++ IG+DLSK+ +PV +EP+S+LQ L E+ EYS +LD AA + +E+++Y+AAF VS+YA+T YR KPFNP++GETYE R D GW+ AEQ+ HHPP +CES W W +F + NKF GK I+ P G + K+ W ++ I+NI +I+++G+M+ NL + K +K S VTG I+ ++ L G W E + Y+ +++ +W+ +P + DKYY F+ FAI LN ++ D+A TDSR RPDQ+ +E G EA EK ++EE Q R+ + K+ G +KPLWF +KS++Y+F +YW K
Sbjct: 497 QEKTGRRDKLPAVQPDISQFSLINLLCKNIGRDLSKVRLPVILNEPLSVLQMLCEELEYSDLLDAAAKSSDSLERMNYIAAFAVSAYASTFYRAGTKPFNPIIGETYEYVRPDK-GWKFIAEQVSHHPPVSVCYCESENWSIWQEFRLKNKFWGKSIEAIPTGSLRVYLKKFNETVHWNKVTTCIYNIFGSNRYIEHYGDMNFTSNLNSSAKITF-HKSNSWVHQKF--EVTGTISCP-DSRKSQLFGKWTEGI----------------YVG--DNARCIWRPGAIPKDHDKYYGFTQFAIDLNNLDSDLAATLPKTDSRFRPDQRYLEMGLITEAEAEKTKIEELQ---RIALAKVKGD----VNWKPLWFK--KHESSKSESYEFTNEYWSAK 860 The following BLAST results are available for this feature:
BLAST of Oxysterol-binding protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Oxysterol-binding protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Oxysterol-binding protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Oxysterol-binding protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30014257 ID=SMED30014257|Name=Oxysterol-binding protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2688bpback to top protein sequence of SMED30014257-orf-1 >SMED30014257-orf-1 ID=SMED30014257-orf-1|Name=SMED30014257-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=822bp METKNQNNVTLSSNIKGYLYKWTNYLKGYQKRWFVLQNGLLSYYRNQSEMback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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